locus-tag	class	description
V529_RS00010	COG0592	DNA-directed DNA polymerase activity
V529_RS00015	COG2501	S4 domain
V529_RS00030	COG0187	DNA topoisomerase II activity
V529_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
V529_RS00070	COG0516	GMP reductase activity
V529_RS00070	COG0517	IMP dehydrogenase activity
V529_RS00075	COG1686	Belongs to the peptidase S11 family
V529_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
V529_RS00105	COG1428	Deoxynucleoside kinase
V529_RS00110	COG1428	Deoxynucleoside kinase
V529_RS00115	COG3858	chitin binding
V529_RS00115	COG1388	LysM domain
V529_RS00120	COG1335	isochorismatase
V529_RS00125	COG0590	tRNA wobble adenosine to inosine editing
V529_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
V529_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
V529_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
V529_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
V529_RS00190	COG3853	Toxic anion resistance protein (TelA)
V529_RS00195	COG1982	Orn Lys Arg decarboxylase major
V529_RS00205	COG3870	Protein conserved in bacteria
V529_RS00210	COG1728	Protein conserved in bacteria
V529_RS00215	COG0470	DNA polymerase III
V529_RS00220	COG1774	PSP1 C-terminal conserved region
V529_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
V529_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
V529_RS00245	COG2002	toxin-antitoxin pair type II binding
V529_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V529_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V529_RS00255	COG0084	hydrolase, TatD family'
V529_RS00260	COG3584	3D domain protein
V529_RS00260	COG3583	domain protein
V529_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
V529_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
V529_RS00280	COG4466	Protein conserved in bacteria
V529_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
V529_RS00300	COG0251	oxidation-reduction process
V529_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
V529_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
V529_RS00340	COG2002	toxin-antitoxin pair type II binding
V529_RS00345	COG2244	polysaccharide biosynthetic process
V529_RS00350	COG3956	TIGRFAM MazG family protein
V529_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
V529_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
V529_RS00375	COG1098	S1 RNA binding domain
V529_RS00390	COG2208	phosphoserine phosphatase activity
V529_RS00395	COG2304	oxidoreductase activity
V529_RS00400	COG0515	serine threonine protein kinase
V529_RS00405	COG0037	tRNA processing
V529_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
V529_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
V529_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
V529_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V529_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
V529_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
V529_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V529_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
V529_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
V529_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
V529_RS00470	COG1396	sequence-specific DNA binding
V529_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
V529_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
V529_RS00500	COG4463	regulation of RNA biosynthetic process
V529_RS00505	COG3880	PFAM UvrB UvrC protein
V529_RS00515	COG0542	response to heat
V529_RS00520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
V529_RS00525	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
V529_RS00530	COG4956	integral membrane protein (PIN domain superfamily)
V529_RS00550	COG1045	serine acetyltransferase
V529_RS00560	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
V529_RS00565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
V529_RS00570	COG3688	RNA-binding protein containing a PIN domain
V529_RS00575	COG1595	DNA-templated transcription, initiation
V529_RS00585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
V529_RS00590	COG0250	Participates in transcription elongation, termination and antitermination
V529_RS00615	COG2813	Specifically methylates the guanine in position
V529_RS00630	COG1358	cellular component organization or biogenesis
V529_RS00655	COG0596	Alpha beta hydrolase
V529_RS00760	COG0201	protein transport
V529_RS00770	COG0024	Methionine aminopeptidase
V529_RS00780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
V529_RS00805	COG1122	ATPase activity
V529_RS00810	COG1122	ATPase activity
V529_RS00815	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
V529_RS00835	COG2226	methyltransferase
V529_RS00840	COG2318	DinB family
V529_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS00855	COG0489	protein tyrosine kinase activity
V529_RS00865	COG2194	sulfuric ester hydrolase activity
V529_RS00870	COG0726	polysaccharide deacetylase
V529_RS00890	COG0738	Major facilitator superfamily
V529_RS00895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
V529_RS00905	COG1063	alcohol dehydrogenase
V529_RS00910	COG0659	secondary active sulfate transmembrane transporter activity
V529_RS00915	COG0385	Bile acid
V529_RS00920	COG2819	hydrolase of the alpha beta superfamily
V529_RS00925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS00930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS00935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V529_RS00940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V529_RS00940	COG2207	Transcriptional regulator
V529_RS00945	COG3876	Protein conserved in bacteria
V529_RS00950	COG1472	Belongs to the glycosyl hydrolase 3 family
V529_RS00955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V529_RS00960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS00960	COG1263	PTS System
V529_RS00970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V529_RS00975	COG1683	Conserved Protein
V529_RS01005	COG1595	DNA-templated transcription, initiation
V529_RS01010	COG5662	AntiSigma factor
V529_RS01015	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
V529_RS01020	COG4856	YbbR-like protein
V529_RS01055	COG5002	protein histidine kinase activity
V529_RS01060	COG1136	(ABC) transporter
V529_RS01065	COG0577	efflux transmembrane transporter activity
V529_RS01070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
V529_RS01085	COG1346	cytolysis
V529_RS01090	COG1380	Effector of murein hydrolase LrgA
V529_RS01095	COG1846	Transcriptional regulator
V529_RS01100	COG1113	amino acid transport
V529_RS01105	COG1011	Hydrolase
V529_RS01110	COG4585	Histidine kinase
V529_RS01115	COG2197	response regulator
V529_RS01120	COG1131	(ABC) transporter
V529_RS01160	COG0531	amino acid
V529_RS01165	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
V529_RS01180	COG0584	glycerophosphoryl diester phosphodiesterase
V529_RS01185	COG2271	Major facilitator Superfamily
V529_RS01195	COG2368	4-hydroxyphenylacetate
V529_RS01205	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS01220	COG0371	Dehydrogenase
V529_RS01230	COG1183	phosphatidylcholine synthase activity
V529_RS01235	COG0586	Pfam SNARE associated Golgi protein
V529_RS01240	COG0688	phosphatidylethanolamine metabolic process
V529_RS01255	COG1301	dicarboxylic acid transport
V529_RS01260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V529_RS01265	COG0833	amino acid
V529_RS01270	COG2040	homocysteine
V529_RS01275	COG1115	amino acid carrier protein
V529_RS01280	COG2066	Belongs to the glutaminase family
V529_RS01285	COG4191	Histidine kinase
V529_RS01290	COG0784	Response regulator, receiver
V529_RS01295	COG3173	Aminoglycoside phosphotransferase
V529_RS01310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V529_RS01315	COG0778	Nitroreductase
V529_RS01320	COG0346	lactoylglutathione lyase activity
V529_RS01325	COG2259	Doxx family
V529_RS01330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS01340	COG3773	Cell wall hydrolase
V529_RS01345	COG3540	Alkaline phosphatase
V529_RS01350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
V529_RS01355	COG0805	protein transport
V529_RS01365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
V529_RS01370	COG0477	Major facilitator Superfamily
V529_RS01375	COG1309	transcriptional regulator
V529_RS01385	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
V529_RS01390	COG3012	SEC-C Motif Domain Protein
V529_RS01390	COG1405	negative regulation of cell septum assembly
V529_RS01395	COG0667	Aldo Keto reductase
V529_RS01405	COG1595	DNA-templated transcription, initiation
V529_RS01410	COG1595	DNA-templated transcription, initiation
V529_RS01415	COG1876	peptidase activity
V529_RS01420	COG0457	Tetratricopeptide repeat
V529_RS01425	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS01430	COG0366	Alpha amylase catalytic
V529_RS01435	COG0803	Belongs to the bacterial solute-binding protein 9 family
V529_RS01440	COG1121	(ABC) transporter
V529_RS01445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
V529_RS01450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS01455	COG2310	stress, protein
V529_RS01460	COG2310	stress, protein
V529_RS01465	COG2310	stress, protein
V529_RS01470	COG0861	Integral membrane protein TerC family
V529_RS01480	COG3853	Toxic anion resistance protein (TelA)
V529_RS01485	COG0477	Major facilitator Superfamily
V529_RS01490	COG0517	IMP dehydrogenase activity
V529_RS01490	COG4175	Glycine betaine
V529_RS01495	COG4176	ABC-type proline glycine betaine transport system permease component
V529_RS01500	COG2113	Glycine betaine
V529_RS01505	COG1473	amidohydrolase
V529_RS01510	COG1288	antiporter activity
V529_RS01520	COG0366	Alpha amylase catalytic
V529_RS01530	COG2814	Major facilitator Superfamily
V529_RS01535	COG1846	Transcriptional regulator
V529_RS01540	COG1280	lysine exporter protein (LysE YggA)
V529_RS01545	COG3403	YqcI/YcgG family
V529_RS01550	COG1113	amino acid transport
V529_RS01555	COG3665	Urea carboxylase-associated protein
V529_RS01570	COG1660	Displays ATPase and GTPase activities
V529_RS01575	COG1082	Xylose isomerase domain protein TIM barrel
V529_RS01580	COG2271	Major facilitator Superfamily
V529_RS01585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
V529_RS01590	COG3458	cephalosporin-C deacetylase activity
V529_RS01595	COG3541	Predicted nucleotidyltransferase
V529_RS01600	COG0506	proline dehydrogenase activity
V529_RS01605	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS01610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V529_RS01615	COG2508	Transcriptional regulator
V529_RS01625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
V529_RS01625	COG1587	Uroporphyrinogen-III synthase
V529_RS01630	COG2146	nitrite reductase [NAD(P)H] activity
V529_RS01635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
V529_RS01640	COG0243	molybdopterin cofactor binding
V529_RS01645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
V529_RS01650	COG2223	nitrite transmembrane transporter activity
V529_RS01655	COG0523	cobalamin synthesis protein
V529_RS01660	COG1063	alcohol dehydrogenase
V529_RS01665	COG1714	RDD family
V529_RS01680	COG3209	COG3209 Rhs family protein
V529_RS01685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
V529_RS01690	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
V529_RS01695	COG1733	regulation of RNA biosynthetic process
V529_RS01705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS01710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS01715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS01720	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
V529_RS01735	COG2364	Membrane
V529_RS01740	COG1126	abc transporter atp-binding protein
V529_RS01745	COG0765	amino acid transport
V529_RS01750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS01755	COG0583	DNA-binding transcription factor activity
V529_RS01760	COG0163	prenyltransferase activity
V529_RS01765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
V529_RS01780	COG3104	oligopeptide transport
V529_RS01785	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS01795	COG0697	spore germination
V529_RS01805	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
V529_RS01810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS01815	COG0456	acetyltransferase
V529_RS01820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS01825	COG0765	amino acid transport
V529_RS01830	COG1126	abc transporter atp-binding protein
V529_RS01835	COG1473	amidohydrolase
V529_RS01840	COG2079	MmgE PrpD family protein
V529_RS01845	COG1136	(ABC) transporter
V529_RS01850	COG0577	efflux transmembrane transporter activity
V529_RS01855	COG0745	RESPONSE REGULATOR receiver
V529_RS01860	COG5002	protein histidine kinase activity
V529_RS01860	COG3850	Histidine kinase
V529_RS01865	COG0457	Tetratricopeptide repeat
V529_RS01875	COG0527	aspartate kinase activity
V529_RS01880	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS01885	COG4605	iron ion homeostasis
V529_RS01890	COG4604	ABC transporter, ATP-binding protein
V529_RS01895	COG4607	ABC-type enterochelin transport system periplasmic component
V529_RS01900	COG2814	Major facilitator Superfamily
V529_RS01905	COG1309	transcriptional regulator
V529_RS01910	COG0778	Nitroreductase
V529_RS01915	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
V529_RS01920	COG0640	Transcriptional regulator
V529_RS01925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V529_RS01930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
V529_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS01940	COG4975	Glucose uptake
V529_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS01950	COG4549	nuclear export factor GLE1
V529_RS01955	COG1276	copper resistance
V529_RS01955	COG2372	response to copper ion
V529_RS01960	COG1349	DNA-binding transcription factor activity
V529_RS01970	COG2213	PTS system mannitol-specific
V529_RS01975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS01985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
V529_RS01990	COG0561	phosphatase activity
V529_RS02000	COG1914	H( )-stimulated, divalent metal cation uptake system
V529_RS02010	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
V529_RS02015	COG1984	allophanate hydrolase subunit 2
V529_RS02020	COG1414	Transcriptional regulator
V529_RS02025	COG2755	lipolytic protein G-D-S-L family
V529_RS02035	COG2329	Antibiotic biosynthesis monooxygenase
V529_RS02040	COG0768	penicillin binding
V529_RS02045	COG4989	oxidoreductase activity
V529_RS02050	COG3711	transcriptional antiterminator
V529_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS02065	COG1917	Cupin 2, conserved barrel domain protein
V529_RS02070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V529_RS02075	COG3871	stress protein (general stress protein 26)
V529_RS02085	COG2814	Major facilitator Superfamily
V529_RS02090	COG1522	sequence-specific DNA binding
V529_RS02095	COG0551	DNA topoisomerase type I activity
V529_RS02095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
V529_RS02100	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
V529_RS02105	COG3706	GGDEF domain
V529_RS02110	COG5298	Protein conserved in bacteria
V529_RS02115	COG1215	transferase activity, transferring glycosyl groups
V529_RS02125	COG0531	amino acid
V529_RS02130	COG0494	nUDIX hydrolase
V529_RS02135	COG0028	Belongs to the TPP enzyme family
V529_RS02170	COG1914	H( )-stimulated, divalent metal cation uptake system
V529_RS02180	COG4876	unkown
V529_RS02190	COG2076	Multidrug Resistance protein
V529_RS02195	COG2217	Heavy metal translocating P-type atpase
V529_RS02200	COG3729	General stress protein
V529_RS02205	COG0662	Cupin 2, conserved barrel domain protein
V529_RS02210	COG2329	Antibiotic biosynthesis monooxygenase
V529_RS02215	COG3546	catalase activity
V529_RS02220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
V529_RS02225	COG3290	protein histidine kinase activity
V529_RS02230	COG4565	transcriptional regulatory protein
V529_RS02235	COG1301	dicarboxylic acid transport
V529_RS02240	COG0628	permease
V529_RS02245	COG1131	(ABC) transporter
V529_RS02250	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V529_RS02260	COG1960	acyl-CoA dehydrogenase activity
V529_RS02270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V529_RS02275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS02285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
V529_RS02290	COG0513	Belongs to the DEAD box helicase family
V529_RS02295	COG3402	PFAM membrane-flanked domain
V529_RS02300	COG3428	Bacterial PH domain
V529_RS02305	COG0705	Rhomboid family
V529_RS02315	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
V529_RS02320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
V529_RS02325	COG0864	Transcriptional regulator
V529_RS02330	COG2337	Toxic component of a toxin-antitoxin (TA) module
V529_RS02335	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS02340	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS02345	COG2172	sigma factor antagonist activity
V529_RS02350	COG2208	phosphoserine phosphatase activity
V529_RS02355	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS02365	COG1191	sigma factor activity
V529_RS02370	COG2208	phosphoserine phosphatase activity
V529_RS02375	COG2183	response to ionizing radiation
V529_RS02435	COG5444	nuclease activity
V529_RS02440	COG2249	NAD(P)H dehydrogenase (quinone) activity
V529_RS02445	COG0457	Tetratricopeptide repeat
V529_RS02450	COG0477	Major facilitator Superfamily
V529_RS02465	COG2030	dehydratase
V529_RS02475	COG1959	2 iron, 2 sulfur cluster binding
V529_RS02480	COG2910	NAD(P)H-binding
V529_RS02485	COG3239	Fatty acid desaturase
V529_RS02490	COG1278	Cold shock
V529_RS02495	COG1329	Transcriptional regulator
V529_RS02500	COG1794	racemase activity, acting on amino acids and derivatives
V529_RS02515	COG3621	Patatin-like phospholipase
V529_RS02525	COG0662	Cupin 2, conserved barrel domain protein
V529_RS02540	COG0277	FAD linked oxidase domain protein
V529_RS02560	COG0662	Cupin 2, conserved barrel domain protein
V529_RS02575	COG1064	alcohol dehydrogenase
V529_RS02580	COG0789	Transcriptional regulator
V529_RS02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V529_RS02600	COG2814	Major facilitator Superfamily
V529_RS02605	COG1309	transcriptional regulator
V529_RS02610	COG5577	PFAM Coat F domain
V529_RS02620	COG1063	alcohol dehydrogenase
V529_RS02625	COG5577	PFAM Coat F domain
V529_RS02640	COG4585	Histidine kinase
V529_RS02645	COG2197	response regulator
V529_RS02650	COG2409	Drug exporters of the RND superfamily
V529_RS02655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
V529_RS02660	COG0488	(ABC) transporter
V529_RS02665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V529_RS02670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS02680	COG2814	Major facilitator Superfamily
V529_RS02685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V529_RS02695	COG0730	response to heat
V529_RS02700	COG0456	acetyltransferase
V529_RS02705	COG1051	belongs to the nudix hydrolase family
V529_RS02710	COG2226	methyltransferase
V529_RS02715	COG1802	Transcriptional regulator
V529_RS02720	COG1819	glycosyl
V529_RS02735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V529_RS02740	COG1388	LysM domain
V529_RS02745	COG2814	Major facilitator Superfamily
V529_RS02750	COG2188	Transcriptional regulator
V529_RS02755	COG2186	Transcriptional regulator
V529_RS02760	COG2807	transmembrane transport
V529_RS02765	COG2076	Multidrug Resistance protein
V529_RS02770	COG2076	Multidrug Resistance protein
V529_RS02775	COG1309	transcriptional regulator
V529_RS02780	COG0531	amino acid
V529_RS02790	COG3832	glyoxalase III activity
V529_RS02795	COG0604	alcohol dehydrogenase
V529_RS02800	COG2814	Major facilitator Superfamily
V529_RS02840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
V529_RS02845	COG0802	atpase or kinase
V529_RS02850	COG1214	PFAM Peptidase M22, glycoprotease
V529_RS02855	COG0456	acetyltransferase
V529_RS02860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
V529_RS02865	COG0488	(ABC) transporter
V529_RS02880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
V529_RS02885	COG0805	protein transport
V529_RS02895	COG1266	CAAX protease self-immunity
V529_RS02915	COG5444	nuclease activity
V529_RS02935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
V529_RS02940	COG0457	Tetratricopeptide repeat
V529_RS02945	COG1063	alcohol dehydrogenase
V529_RS02950	COG2211	Major facilitator Superfamily
V529_RS02955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V529_RS02965	COG1842	Phage shock protein A
V529_RS02970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
V529_RS02975	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
V529_RS02980	COG4260	virion core protein, lumpy skin disease virus
V529_RS02985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
V529_RS02985	COG2755	lipolytic protein G-D-S-L family
V529_RS02995	COG1595	DNA-templated transcription, initiation
V529_RS03000	COG1063	alcohol dehydrogenase
V529_RS03005	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
V529_RS03010	COG0823	Involved in the tonB-independent uptake of proteins
V529_RS03025	COG2132	Multicopper oxidase
V529_RS03030	COG1113	amino acid transport
V529_RS03035	COG0714	Associated with various cellular activities
V529_RS03040	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
V529_RS03045	COG1305	Transglutaminase-like
V529_RS03065	COG2252	PERMEase
V529_RS03070	COG3064	Membrane
V529_RS03085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
V529_RS03090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
V529_RS03095	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
V529_RS03100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
V529_RS03105	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
V529_RS03120	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
V529_RS03130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
V529_RS03135	COG0138	bifunctional purine biosynthesis protein purh
V529_RS03140	COG0151	Belongs to the GarS family
V529_RS03150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
V529_RS03155	COG1470	cell adhesion involved in biofilm formation
V529_RS03160	COG4496	protein, YerC YecD
V529_RS03165	COG0069	glutamate synthase activity
V529_RS03180	COG0210	DNA helicase
V529_RS03190	COG4851	CamS sex pheromone cAM373 precursor
V529_RS03195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V529_RS03200	COG1285	pathogenesis
V529_RS03205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V529_RS03225	COG1309	transcriptional regulator
V529_RS03230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
V529_RS03235	COG1597	lipid kinase activity
V529_RS03240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
V529_RS03245	COG0745	RESPONSE REGULATOR receiver
V529_RS03260	COG5002	protein histidine kinase activity
V529_RS03265	COG1024	Enoyl-CoA hydratase
V529_RS03270	COG1024	Enoyl-CoA hydratase
V529_RS03275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03290	COG1131	(ABC) transporter
V529_RS03305	COG4221	oxidoreductase activity
V529_RS03305	COG3321	synthase
V529_RS03305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03305	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03310	COG3321	synthase
V529_RS03310	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03315	COG3321	synthase
V529_RS03315	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03320	COG3321	synthase
V529_RS03325	COG4221	oxidoreductase activity
V529_RS03325	COG0300	oxidoreductase activity
V529_RS03325	COG3321	synthase
V529_RS03325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03330	COG3321	synthase
V529_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03335	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03335	COG3321	synthase
V529_RS03345	COG3321	synthase
V529_RS03345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS03350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03350	COG3321	synthase
V529_RS03350	COG4221	oxidoreductase activity
V529_RS03360	COG2070	2-Nitropropane dioxygenase
V529_RS03360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V529_RS03365	COG3425	synthase
V529_RS03370	COG5444	nuclease activity
V529_RS03400	COG3546	catalase activity
V529_RS03405	COG0454	-acetyltransferase
V529_RS03415	COG2323	membrane
V529_RS03420	COG2329	Antibiotic biosynthesis monooxygenase
V529_RS03425	COG0346	lactoylglutathione lyase activity
V529_RS03430	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS03435	COG0196	riboflavin kinase activity
V529_RS03440	COG0670	Belongs to the BI1 family
V529_RS03445	COG1846	Transcriptional regulator
V529_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
V529_RS03460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V529_RS03460	COG2124	cytochrome p450
V529_RS03470	COG1368	sulfuric ester hydrolase activity
V529_RS03475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
V529_RS03480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS03485	COG1442	glycosyl transferase family 8
V529_RS03490	COG1216	Glycosyl transferase, family 2
V529_RS03495	COG1442	glycosyl transferase family 8
V529_RS03500	COG2223	nitrite transmembrane transporter activity
V529_RS03505	COG0531	amino acid
V529_RS03510	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS03515	COG0840	transmembrane signaling receptor activity
V529_RS03520	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS03525	COG0463	Glycosyl transferase, family 2
V529_RS03525	COG0457	Tetratricopeptide repeat
V529_RS03530	COG0488	(ABC) transporter
V529_RS03535	COG0789	Transcriptional regulator
V529_RS03540	COG2814	Major facilitator Superfamily
V529_RS03545	COG0488	(ABC) transporter
V529_RS03550	COG0513	Belongs to the DEAD box helicase family
V529_RS03555	COG0456	acetyltransferase
V529_RS03560	COG2130	NADP-dependent
V529_RS03575	COG3866	Pectate lyase
V529_RS03580	COG0471	metal ion transport
V529_RS03600	COG0784	Response regulator, receiver
V529_RS03600	COG2205	protein histidine kinase activity
V529_RS03605	COG3279	Response regulator of the LytR AlgR family
V529_RS03615	COG3764	Sortase (surface protein transpeptidase)
V529_RS03625	COG3290	protein histidine kinase activity
V529_RS03630	COG4565	transcriptional regulatory protein
V529_RS03635	COG3181	Tripartite tricarboxylate transporter family receptor
V529_RS03640	COG2851	Citrate transporter
V529_RS03645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS03650	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
V529_RS03660	COG2258	MOSC domain
V529_RS03670	COG0024	Methionine aminopeptidase
V529_RS03675	COG1263	PTS System
V529_RS03675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS03685	COG1368	sulfuric ester hydrolase activity
V529_RS03695	COG0071	Belongs to the small heat shock protein (HSP20) family
V529_RS03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS03710	COG1263	PTS System
V529_RS03715	COG0366	Alpha amylase catalytic
V529_RS03720	COG2188	Transcriptional regulator
V529_RS03725	COG0778	Nitroreductase
V529_RS03740	COG0737	Belongs to the 5'-nucleotidase family
V529_RS03745	COG0693	protein deglycase activity
V529_RS03750	COG1609	Transcriptional regulator
V529_RS03765	COG2814	Major facilitator Superfamily
V529_RS03775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
V529_RS03780	COG4980	gas vesicle protein
V529_RS03785	COG1295	ribonuclease BN
V529_RS03790	COG0477	Major facilitator Superfamily
V529_RS03795	COG0387	Pfam Sodium calcium exchanger
V529_RS03805	COG0668	transmembrane transport
V529_RS03810	COG0535	radical SAM domain protein
V529_RS03820	COG0726	polysaccharide deacetylase
V529_RS03840	COG0745	RESPONSE REGULATOR receiver
V529_RS03845	COG2205	protein histidine kinase activity
V529_RS03850	COG2084	Dehydrogenase
V529_RS03860	COG0598	Magnesium transport protein CorA
V529_RS03865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
V529_RS03870	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
V529_RS03880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
V529_RS03885	COG4637	Psort location Cytoplasmic, score
V529_RS03890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V529_RS03895	COG0022	dehydrogenase e1 component
V529_RS03900	COG0508	dehydrogenase complex catalyzes the overall conversion of
V529_RS03905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V529_RS03910	COG3284	Transcriptional regulator
V529_RS03920	COG1486	melibiose metabolic process
V529_RS03925	COG1737	Transcriptional regulator
V529_RS03930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS03930	COG1263	PTS System
V529_RS03935	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS03940	COG1132	(ABC) transporter
V529_RS03945	COG1132	(ABC) transporter
V529_RS03950	COG2259	Doxx family
V529_RS03955	COG2514	catechol 2,3-dioxygenase activity
V529_RS03965	COG1695	Transcriptional regulator
V529_RS03970	COG2249	NAD(P)H dehydrogenase (quinone) activity
V529_RS03975	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
V529_RS03980	COG0574	Belongs to the PEP-utilizing enzyme family
V529_RS03980	COG3848	Pyruvate phosphate dikinase
V529_RS03985	COG2732	(Barnase) inhibitor
V529_RS03990	COG2318	DinB family
V529_RS03995	COG2814	Major facilitator Superfamily
V529_RS04000	COG1846	Transcriptional regulator
V529_RS04005	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
V529_RS04005	COG0392	lysyltransferase activity
V529_RS04010	COG0384	phenazine biosynthesis protein PhzF
V529_RS04015	COG0778	Nitroreductase
V529_RS04025	COG1090	epimerase
V529_RS04040	COG2814	Major facilitator Superfamily
V529_RS04050	COG3591	Belongs to the peptidase S1B family
V529_RS04065	COG3103	Sh3 type 3 domain protein
V529_RS04070	COG5658	integral membrane protein
V529_RS04075	COG0596	Alpha beta hydrolase
V529_RS04080	COG0463	Glycosyl transferase, family 2
V529_RS04085	COG4485	Bacterial membrane protein, YfhO
V529_RS04090	COG1988	membrane-bound metal-dependent
V529_RS04095	COG1194	a g-specific adenine glycosylase
V529_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS04125	COG1132	(ABC) transporter
V529_RS04130	COG4129	membrane
V529_RS04140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
V529_RS04145	COG0735	belongs to the Fur family
V529_RS04255	COG1757	Na H antiporter
V529_RS04260	COG3340	Belongs to the peptidase S51 family
V529_RS04270	COG0277	FAD linked oxidase domain protein
V529_RS04280	COG0747	negative chemotaxis
V529_RS04285	COG0601	transmembrane transport
V529_RS04290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V529_RS04295	COG0444	Belongs to the ABC transporter superfamily
V529_RS04300	COG4608	Belongs to the ABC transporter superfamily
V529_RS04305	COG0753	catalase activity
V529_RS04315	COG1116	anion transmembrane transporter activity
V529_RS04320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
V529_RS04325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
V529_RS04345	COG1476	TRANSCRIPTIONal
V529_RS04355	COG3382	B3 4 domain protein
V529_RS04360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
V529_RS04370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
V529_RS04375	COG0789	Transcriptional regulator
V529_RS04380	COG1664	Polymer-forming cytoskeletal
V529_RS04385	COG1664	Polymer-forming cytoskeletal
V529_RS04390	COG2766	serine protein kinase
V529_RS04400	COG1846	Transcriptional regulator
V529_RS04405	COG1566	PFAM secretion protein HlyD family protein
V529_RS04410	COG2814	Major facilitator Superfamily
V529_RS04415	COG0655	NAD(P)H dehydrogenase (quinone) activity
V529_RS04430	COG1725	Transcriptional regulator
V529_RS04435	COG1131	(ABC) transporter
V529_RS04440	COG1131	(ABC) transporter
V529_RS04445	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V529_RS04450	COG1278	Cold shock
V529_RS04455	COG1464	Belongs to the NlpA lipoprotein family
V529_RS04460	COG3706	GGDEF domain
V529_RS04465	COG1823	symporter activity
V529_RS04485	COG5577	PFAM Coat F domain
V529_RS04490	COG4085	toxin activity
V529_RS04490	COG1525	nuclease
V529_RS04490	COG0737	Belongs to the 5'-nucleotidase family
V529_RS04495	COG3764	Sortase (surface protein transpeptidase)
V529_RS04500	COG0564	pseudouridine synthase activity
V529_RS04510	COG0517	IMP dehydrogenase activity
V529_RS04515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
V529_RS04520	COG3153	acetyltransferase
V529_RS04520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
V529_RS04525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V529_RS04530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
V529_RS04535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
V529_RS04545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
V529_RS04550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
V529_RS04555	COG4585	Histidine kinase
V529_RS04555	COG2203	Gaf domain
V529_RS04560	COG2197	response regulator
V529_RS04565	COG0431	NADPH-dependent FMN reductase
V529_RS04580	COG1388	LysM domain
V529_RS04580	COG0791	NLP P60 protein
V529_RS04585	COG1959	2 iron, 2 sulfur cluster binding
V529_RS04590	COG0668	transmembrane transport
V529_RS04595	COG2719	SpoVR family
V529_RS04600	COG1785	Belongs to the alkaline phosphatase family
V529_RS04605	COG1388	LysM domain
V529_RS04605	COG0791	NLP P60 protein
V529_RS04610	COG0583	DNA-binding transcription factor activity
V529_RS04615	COG0372	Belongs to the citrate synthase family
V529_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS04625	COG0531	amino acid
V529_RS04630	COG0733	neurotransmitter:sodium symporter activity
V529_RS04645	COG1595	DNA-templated transcription, initiation
V529_RS04650	COG0204	Acyl-transferase
V529_RS04655	COG1253	flavin adenine dinucleotide binding
V529_RS04660	COG0789	Transcriptional regulator
V529_RS04665	COG0436	Aminotransferase
V529_RS04670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V529_RS04675	COG1253	flavin adenine dinucleotide binding
V529_RS04680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
V529_RS04685	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
V529_RS04690	COG0584	glycerophosphoryl diester phosphodiesterase
V529_RS04695	COG0668	transmembrane transport
V529_RS04700	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
V529_RS04705	COG0726	polysaccharide deacetylase
V529_RS04710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V529_RS04715	COG3226	Transcriptional regulator
V529_RS04725	COG0589	response to stress
V529_RS04730	COG1132	(ABC) transporter
V529_RS04735	COG1132	(ABC) transporter
V529_RS04740	COG0702	epimerase
V529_RS04755	COG0189	ligase activity
V529_RS04760	COG0189	ligase activity
V529_RS04775	COG4335	DNA alkylation repair
V529_RS04780	COG0561	phosphatase activity
V529_RS04785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
V529_RS04795	COG0475	glutathione-regulated potassium exporter activity
V529_RS04800	COG0490	domain, Protein
V529_RS04810	COG1024	Enoyl-CoA hydratase
V529_RS04820	COG4152	abc transporter atp-binding protein
V529_RS04825	COG1668	transmembrane transport
V529_RS04830	COG0420	3'-5' exonuclease activity
V529_RS04835	COG4717	serine-type aminopeptidase activity
V529_RS04850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
V529_RS04885	COG4980	gas vesicle protein
V529_RS04900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
V529_RS04905	COG0537	adenosine 5'-monophosphoramidase activity
V529_RS04910	COG1131	(ABC) transporter
V529_RS04915	COG4473	ABC transporter
V529_RS04925	COG1473	amidohydrolase
V529_RS04930	COG3069	C4-dicarboxylate transmembrane transporter activity
V529_RS04935	COG2329	Antibiotic biosynthesis monooxygenase
V529_RS04940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V529_RS04950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
V529_RS04955	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
V529_RS04960	COG1309	transcriptional regulator
V529_RS04965	COG1511	domain protein
V529_RS04970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V529_RS04980	COG1363	Peptidase, m42
V529_RS04985	COG1301	dicarboxylic acid transport
V529_RS04990	COG1234	tRNA 3'-trailer cleavage
V529_RS04995	COG0095	Lipoate-protein ligase
V529_RS05000	COG0702	epimerase
V529_RS05005	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS05015	COG0501	Belongs to the peptidase M48B family
V529_RS05020	COG1404	Belongs to the peptidase S8 family
V529_RS05030	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
V529_RS05035	COG0406	alpha-ribazole phosphatase activity
V529_RS05040	COG0183	Belongs to the thiolase family
V529_RS05045	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS05050	COG1268	BioY protein
V529_RS05055	COG0840	transmembrane signaling receptor activity
V529_RS05060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V529_RS05060	COG0723	plastoquinol--plastocyanin reductase activity
V529_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS05075	COG4903	ComK protein
V529_RS05085	COG5646	InterPro IPR014922
V529_RS05110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V529_RS05125	COG0398	Pfam SNARE associated Golgi protein
V529_RS05130	COG0681	Belongs to the peptidase S26 family
V529_RS05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
V529_RS05140	COG1846	Transcriptional regulator
V529_RS05145	COG3180	Ammonia monooxygenase
V529_RS05150	COG2814	Major facilitator Superfamily
V529_RS05160	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
V529_RS05165	COG2323	membrane
V529_RS05180	COG0420	3'-5' exonuclease activity
V529_RS05185	COG0419	ATPase involved in DNA repair
V529_RS05190	COG1403	HNH endonuclease
V529_RS05230	COG0179	Fumarylacetoacetate (FAA) hydrolase
V529_RS05250	COG0367	asparagine synthase
V529_RS05255	COG1562	ergosterol biosynthetic process
V529_RS05260	COG0534	Mate efflux family protein
V529_RS05265	COG1917	Cupin 2, conserved barrel domain protein
V529_RS05265	COG2207	Transcriptional regulator
V529_RS05270	COG0673	inositol 2-dehydrogenase activity
V529_RS05275	COG2318	DinB family
V529_RS05280	COG1279	arginine transmembrane transporter activity
V529_RS05285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V529_RS05290	COG1357	PFAM Pentapeptide repeats (8 copies)
V529_RS05295	COG2153	protein acetylation
V529_RS05300	COG0646	methionine synthase
V529_RS05300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
V529_RS05310	COG2996	Protein conserved in bacteria
V529_RS05315	COG1744	ABC transporter substrate-binding protein PnrA-like
V529_RS05320	COG0840	transmembrane signaling receptor activity
V529_RS05325	COG2124	cytochrome p450
V529_RS05330	COG1307	EDD domain protein, DegV family
V529_RS05335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS05350	COG0561	phosphatase activity
V529_RS05355	COG1073	alpha beta
V529_RS05360	COG2151	metal-sulfur cluster biosynthetic enzyme
V529_RS05370	COG0277	FAD linked oxidase domain protein
V529_RS05375	COG2271	Major facilitator Superfamily
V529_RS05385	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
V529_RS05395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
V529_RS05400	COG0505	Belongs to the CarA family
V529_RS05405	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
V529_RS05410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
V529_RS05430	COG2267	carboxylic ester hydrolase activity
V529_RS05440	COG1744	ABC transporter substrate-binding protein PnrA-like
V529_RS05455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V529_RS05460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
V529_RS05465	COG5504	Zn-dependent protease
V529_RS05470	COG0444	Belongs to the ABC transporter superfamily
V529_RS05475	COG4608	Belongs to the ABC transporter superfamily
V529_RS05485	COG0601	transmembrane transport
V529_RS05490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V529_RS05500	COG0180	Tryptophanyl-tRNA synthetase
V529_RS05505	COG4166	transmembrane transport
V529_RS05510	COG0601	transmembrane transport
V529_RS05515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V529_RS05520	COG0444	Belongs to the ABC transporter superfamily
V529_RS05525	COG4608	Belongs to the ABC transporter superfamily
V529_RS05540	COG1393	Belongs to the ArsC family
V529_RS05545	COG0861	Integral membrane protein TerC family
V529_RS05550	COG4862	establishment of competence for transformation
V529_RS05555	COG4469	Competence protein
V529_RS05560	COG1164	Oligoendopeptidase f
V529_RS05570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
V529_RS05575	COG2346	COG2346, Truncated hemoglobins
V529_RS05580	COG0741	lytic transglycosylase activity
V529_RS05585	COG4116	CYTH
V529_RS05595	COG2357	RelA SpoT domain protein
V529_RS05600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
V529_RS05605	COG0564	pseudouridine synthase activity
V529_RS05615	COG0475	glutathione-regulated potassium exporter activity
V529_RS05615	COG0569	domain protein
V529_RS05620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
V529_RS05625	COG0352	thiamine-phosphate diphosphorylase activity
V529_RS05630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V529_RS05635	COG2104	thiamine diphosphate biosynthetic process
V529_RS05645	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V529_RS05650	COG0351	phosphomethylpyrimidine kinase
V529_RS05655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
V529_RS05710	COG0210	DNA helicase
V529_RS05725	COG2153	protein acetylation
V529_RS05735	COG2382	esterase
V529_RS05740	COG0626	cystathionine gamma-synthase activity
V529_RS05745	COG0626	cystathionine gamma-synthase activity
V529_RS05775	COG5444	nuclease activity
V529_RS05785	COG0346	lactoylglutathione lyase activity
V529_RS05790	COG2367	Beta-lactamase
V529_RS05795	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
V529_RS05800	COG0477	Major facilitator Superfamily
V529_RS05805	COG1846	Transcriptional regulator
V529_RS05815	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
V529_RS05820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
V529_RS05825	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
V529_RS05830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS05830	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS05835	COG1447	Phosphotransferase system cellobiose-specific component IIA
V529_RS05865	COG1285	pathogenesis
V529_RS05870	COG2205	protein histidine kinase activity
V529_RS05880	COG3383	formate dehydrogenase (NAD+) activity
V529_RS05885	COG2427	Protein of unknown function (DUF1641)
V529_RS05890	COG2124	cytochrome p450
V529_RS05895	COG1819	glycosyl
V529_RS05905	COG1587	Uroporphyrinogen-III synthase
V529_RS05910	COG0390	transport system, permease component
V529_RS05915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V529_RS05920	COG0697	spore germination
V529_RS05925	COG4297	protein containing double-stranded beta helix domain
V529_RS05935	COG1252	NADH dehydrogenase
V529_RS05945	COG2211	Major facilitator Superfamily
V529_RS05950	COG1609	Transcriptional regulator
V529_RS05955	COG0246	Mannitol dehydrogenase
V529_RS05960	COG2721	sulfolactate sulfo-lyase activity
V529_RS05965	COG0730	response to heat
V529_RS05970	COG2318	DinB family
V529_RS05975	COG0457	Tetratricopeptide repeat
V529_RS05985	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS05985	COG5632	N-Acetylmuramoyl-L-alanine amidase
V529_RS05985	COG1388	LysM domain
V529_RS05995	COG4195	phage-related replication protein
V529_RS06000	COG2856	Zn peptidase
V529_RS06005	COG1396	sequence-specific DNA binding
V529_RS06015	COG1522	sequence-specific DNA binding
V529_RS06020	COG1484	DNA-dependent DNA replication
V529_RS06035	COG1595	DNA-templated transcription, initiation
V529_RS06040	COG3728	DNA packaging
V529_RS06040	COG5484	DNA packaging
V529_RS06075	COG5632	N-Acetylmuramoyl-L-alanine amidase
V529_RS06075	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS06090	COG0306	phosphate transporter
V529_RS06095	COG1392	Phosphate transport regulator
V529_RS06100	COG0531	amino acid
V529_RS06105	COG0346	lactoylglutathione lyase activity
V529_RS06110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
V529_RS06115	COG0463	Glycosyl transferase, family 2
V529_RS06120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V529_RS06125	COG0477	Major facilitator Superfamily
V529_RS06130	COG2362	D-Aminopeptidase
V529_RS06135	COG0601	transmembrane transport
V529_RS06140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
V529_RS06145	COG0444	Belongs to the ABC transporter superfamily
V529_RS06150	COG4166	transmembrane transport
V529_RS06155	COG1619	proteins homologs of microcin C7 resistance protein MccF
V529_RS06160	COG4948	Mandelate Racemase Muconate Lactonizing
V529_RS06165	COG0791	NLP P60 protein
V529_RS06170	COG4608	Belongs to the ABC transporter superfamily
V529_RS06175	COG2706	6-phosphogluconolactonase activity
V529_RS06180	COG1834	amidinotransferase
V529_RS06185	COG1607	acyl-coa hydrolase
V529_RS06190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V529_RS06195	COG2076	Multidrug Resistance protein
V529_RS06200	COG2076	Multidrug Resistance protein
V529_RS06205	COG0788	formyltetrahydrofolate deformylase activity
V529_RS06210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
V529_RS06220	COG1764	response to oxidative stress
V529_RS06225	COG1846	Transcriptional regulator
V529_RS06230	COG1764	response to oxidative stress
V529_RS06245	COG0457	Tetratricopeptide repeat
V529_RS06245	COG0463	Glycosyl transferase, family 2
V529_RS06255	COG2814	Major facilitator Superfamily
V529_RS06260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V529_RS06270	COG1404	Belongs to the peptidase S8 family
V529_RS06275	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS06280	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
V529_RS06285	COG1122	ATPase activity
V529_RS06290	COG4721	ABC-type cobalt transport system, permease component
V529_RS06300	COG3858	chitin binding
V529_RS06300	COG1388	LysM domain
V529_RS06305	COG2239	Acts as a magnesium transporter
V529_RS06310	COG0789	Transcriptional regulator
V529_RS06320	COG1846	Transcriptional regulator
V529_RS06325	COG0726	polysaccharide deacetylase
V529_RS06330	COG3285	dna ligase
V529_RS06330	COG1793	dna ligase
V529_RS06335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
V529_RS06345	COG0586	Pfam SNARE associated Golgi protein
V529_RS06350	COG0861	Integral membrane protein TerC family
V529_RS06355	COG1191	sigma factor activity
V529_RS06380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
V529_RS06385	COG2323	membrane
V529_RS06390	COG3594	Acyltransferase
V529_RS06395	COG5002	protein histidine kinase activity
V529_RS06400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
V529_RS06415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
V529_RS06420	COG0436	Aminotransferase
V529_RS06450	COG3852	Histidine kinase
V529_RS06455	COG1846	Transcriptional regulator
V529_RS06460	COG1360	Flagellar Motor Protein
V529_RS06465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
V529_RS06470	COG0542	response to heat
V529_RS06480	COG3949	Membrane
V529_RS06495	COG0720	synthase
V529_RS06500	COG0602	queuosine metabolic process
V529_RS06515	COG1733	regulation of RNA biosynthetic process
V529_RS06520	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS06530	COG4873	Protein conserved in bacteria
V529_RS06540	COG3773	Cell wall hydrolase
V529_RS06545	COG2244	polysaccharide biosynthetic process
V529_RS06550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS06555	COG2217	Heavy metal translocating P-type atpase
V529_RS06560	COG0006	proline dipeptidase activity
V529_RS06565	COG1609	Transcriptional regulator
V529_RS06570	COG3711	transcriptional antiterminator
V529_RS06575	COG1263	PTS System
V529_RS06575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS06575	COG2190	(PTS) system
V529_RS06580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS06585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
V529_RS06595	COG1533	DNA photolyase activity
V529_RS06600	COG0840	transmembrane signaling receptor activity
V529_RS06605	COG2084	Dehydrogenase
V529_RS06610	COG2340	Cysteine-rich secretory protein family
V529_RS06615	COG0768	penicillin binding
V529_RS06620	COG4191	Histidine kinase
V529_RS06625	COG0436	Aminotransferase
V529_RS06630	COG0784	Response regulator, receiver
V529_RS06630	COG0835	chemotaxis
V529_RS06640	COG2814	Major facilitator Superfamily
V529_RS06645	COG1376	ErfK ybiS ycfS ynhG family protein
V529_RS06650	COG1408	metallophosphoesterase
V529_RS06655	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS06665	COG2200	EAL domain
V529_RS06670	COG4703	Protein of unknown function (DUF1797)
V529_RS06675	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
V529_RS06685	COG0517	IMP dehydrogenase activity
V529_RS06690	COG0583	DNA-binding transcription factor activity
V529_RS06695	COG0716	FMN binding
V529_RS06705	COG0716	FMN binding
V529_RS06725	COG0668	transmembrane transport
V529_RS06730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS06750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V529_RS06755	COG0303	'Molybdopterin
V529_RS06760	COG1763	Mo-molybdopterin cofactor biosynthetic process
V529_RS06765	COG0314	molybdopterin synthase activity
V529_RS06770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
V529_RS06780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
V529_RS06785	COG1136	(ABC) transporter
V529_RS06790	COG0577	efflux transmembrane transporter activity
V529_RS06795	COG1349	DNA-binding transcription factor activity
V529_RS06800	COG1105	Belongs to the carbohydrate kinase PfkB family
V529_RS06805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS06805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V529_RS06805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V529_RS06810	COG0681	Belongs to the peptidase S26 family
V529_RS06820	COG0488	(ABC) transporter
V529_RS06825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
V529_RS06830	COG2309	aminopeptidase activity
V529_RS06835	COG1077	Cell shape determining protein MreB Mrl
V529_RS06845	COG2002	toxin-antitoxin pair type II binding
V529_RS06850	COG3852	Histidine kinase
V529_RS06855	COG2105	PFAM AIG2 family protein
V529_RS06855	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
V529_RS06860	COG0569	domain protein
V529_RS06870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
V529_RS06880	COG0561	phosphatase activity
V529_RS06885	COG0242	peptide deformylase activity
V529_RS06895	COG0497	DNA recombination
V529_RS06905	COG4221	oxidoreductase activity
V529_RS06905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS06905	COG3321	synthase
V529_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS06910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS06910	COG4221	oxidoreductase activity
V529_RS06910	COG0300	oxidoreductase activity
V529_RS06910	COG3321	synthase
V529_RS06915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS06915	COG3321	synthase
V529_RS06915	COG4221	oxidoreductase activity
V529_RS06920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS06920	COG0300	oxidoreductase activity
V529_RS06920	COG3321	synthase
V529_RS06920	COG4221	oxidoreductase activity
V529_RS06925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS06925	COG0300	oxidoreductase activity
V529_RS06925	COG3321	synthase
V529_RS06925	COG4221	oxidoreductase activity
V529_RS06930	COG0300	oxidoreductase activity
V529_RS06930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS06930	COG3321	synthase
V529_RS06930	COG4221	oxidoreductase activity
V529_RS06935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS06935	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS06935	COG3321	synthase
V529_RS06935	COG4221	oxidoreductase activity
V529_RS06940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
V529_RS06945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V529_RS06950	COG0022	dehydrogenase e1 component
V529_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
V529_RS06960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V529_RS06965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS06975	COG1982	Orn Lys Arg decarboxylase major
V529_RS06995	COG0483	inositol monophosphate 1-phosphatase activity
V529_RS07005	COG3227	Zinc metalloprotease (Elastase)
V529_RS07025	COG1217	gtp-binding protein TYPA
V529_RS07035	COG4896	Protein conserved in bacteria
V529_RS07045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
V529_RS07050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
V529_RS07055	COG2066	Belongs to the glutaminase family
V529_RS07065	COG0772	Belongs to the SEDS family
V529_RS07070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
V529_RS07085	COG2010	Cytochrome c
V529_RS07085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
V529_RS07090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
V529_RS07095	COG1845	cytochrome c oxidase, subunit III
V529_RS07100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
V529_RS07105	COG3336	cytochrome c oxidase
V529_RS07115	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
V529_RS07120	COG2340	Cysteine-rich secretory protein family
V529_RS07135	COG3679	Belongs to the UPF0342 family
V529_RS07145	COG0742	ribosomal rna small subunit methyltransferase
V529_RS07155	COG3314	Sporulation integral membrane protein YlbJ
V529_RS07160	COG1752	Esterase of the alpha-beta hydrolase superfamily
V529_RS07165	COG3480	Lon protease (S16) C-terminal proteolytic domain
V529_RS07175	COG1399	metal-binding, possibly nucleic acid-binding protein
V529_RS07190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
V529_RS07210	COG4839	cell division protein FtsL
V529_RS07215	COG0768	penicillin binding
V529_RS07220	COG0768	penicillin binding
V529_RS07240	COG0772	Belongs to the SEDS family
V529_RS07255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
V529_RS07260	COG0849	cell division
V529_RS07265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
V529_RS07270	COG1404	Belongs to the peptidase S8 family
V529_RS07270	COG4412	M6 family metalloprotease domain protein
V529_RS07280	COG1191	sigma factor activity
V529_RS07285	COG1191	sigma factor activity
V529_RS07290	COG1119	ATPase activity
V529_RS07295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V529_RS07300	COG1873	PFAM PRC-barrel domain
V529_RS07305	COG1496	oxidoreductase activity
V529_RS07310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
V529_RS07320	COG0762	integral membrane protein
V529_RS07325	COG2302	S4 RNA-binding domain
V529_RS07330	COG3599	regulation of cell shape
V529_RS07340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
V529_RS07345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V529_RS07355	COG0564	pseudouridine synthase activity
V529_RS07365	COG2233	PERMEase
V529_RS07375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
V529_RS07380	COG0505	Belongs to the CarA family
V529_RS07385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
V529_RS07400	COG0284	orotidine-5'-phosphate decarboxylase activity
V529_RS07405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
V529_RS07415	COG0306	phosphate transporter
V529_RS07430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
V529_RS07435	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
V529_RS07440	COG1648	precorrin-2 dehydrogenase activity
V529_RS07455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
V529_RS07460	COG1561	YicC-like family, N-terminal region
V529_RS07470	COG0194	GDP metabolic process
V529_RS07480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
V529_RS07485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
V529_RS07490	COG0242	peptide deformylase activity
V529_RS07500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
V529_RS07500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
V529_RS07510	COG0631	protein serine/threonine phosphatase activity
V529_RS07515	COG0515	serine threonine protein kinase
V529_RS07515	COG2815	serine threonine protein kinase
V529_RS07525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
V529_RS07530	COG1564	THIamine pyrophosphokinase
V529_RS07545	COG1302	Protein conserved in bacteria
V529_RS07550	COG1461	Dihydroxyacetone kinase
V529_RS07555	COG1760	l-serine dehydratase
V529_RS07560	COG1760	l-serine dehydratase
V529_RS07565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
V529_RS07580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V529_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS07600	COG1196	nuclear chromosome segregation
V529_RS07605	COG0552	protein localization to endoplasmic reticulum
V529_RS07620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
V529_RS07630	COG1837	Belongs to the UPF0109 family
V529_RS07655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
V529_RS07670	COG2257	FlhB HrpN YscU SpaS Family
V529_RS07680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
V529_RS07685	COG0758	DNA mediated transformation
V529_RS07690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
V529_RS07700	COG4974	Belongs to the 'phage' integrase family
V529_RS07720	COG1815	bacterial-type flagellum-dependent cell motility
V529_RS07725	COG1558	bacterial-type flagellum-dependent cell motility
V529_RS07730	COG1677	Flagellar hook-basal body complex protein FliE
V529_RS07735	COG1766	The M ring may be actively involved in energy transduction
V529_RS07740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V529_RS07745	COG1317	bacterial-type flagellum organization
V529_RS07750	COG1157	protein secretion by the type III secretion system
V529_RS07755	COG2882	bacterial-type flagellum organization
V529_RS07760	COG3334	PFAM MgtE intracellular
V529_RS07765	COG3144	bacterial-type flagellum assembly
V529_RS07770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
V529_RS07775	COG4786	Flagellar basal body rod
V529_RS07780	COG1582	Flagellar protein (FlbD)
V529_RS07785	COG1580	Controls the rotational direction of flagella during chemotaxis
V529_RS07790	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V529_RS07795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
V529_RS07795	COG1776	CheC inhibitor of MCP methylation
V529_RS07800	COG2201	protein-glutamate methylesterase activity
V529_RS07805	COG3190	flagellar
V529_RS07810	COG1338	Plays a role in the flagellum-specific transport system
V529_RS07815	COG1987	bacterial-type flagellum assembly
V529_RS07820	COG1684	flagellar biosynthetic protein fliR
V529_RS07825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
V529_RS07830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
V529_RS07835	COG1419	protein localization to endoplasmic reticulum
V529_RS07840	COG0455	bacterial-type flagellum organization
V529_RS07845	COG2201	protein-glutamate methylesterase activity
V529_RS07850	COG0643	Histidine kinase
V529_RS07850	COG2198	Histidine kinase
V529_RS07855	COG0835	chemotaxis
V529_RS07860	COG1776	CheC inhibitor of MCP methylation
V529_RS07870	COG1191	sigma factor activity
V529_RS07900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
V529_RS07905	COG4589	Belongs to the CDS family
V529_RS07915	COG0750	zinc metalloprotease
V529_RS07925	COG2176	DNA-directed DNA polymerase activity
V529_RS07935	COG0195	Participates in both transcription termination and antitermination
V529_RS07940	COG2740	Nucleic-acid-binding protein implicated in transcription termination
V529_RS07945	COG1358	cellular component organization or biogenesis
V529_RS07955	COG1550	Protein conserved in bacteria
V529_RS07970	COG0196	riboflavin kinase activity
V529_RS07985	COG0726	polysaccharide deacetylase
V529_RS07990	COG0612	Peptidase, M16
V529_RS07995	COG1873	PFAM PRC-barrel domain
V529_RS08000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
V529_RS08005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
V529_RS08010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
V529_RS08015	COG0527	aspartate kinase activity
V529_RS08025	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
V529_RS08030	COG0740	serine-type endopeptidase activity
V529_RS08040	COG4980	gas vesicle protein
V529_RS08040	COG1674	ftsk spoiiie
V529_RS08045	COG2188	Transcriptional regulator
V529_RS08050	COG2814	Major facilitator Superfamily
V529_RS08055	COG1846	Transcriptional regulator
V529_RS08060	COG2409	Drug exporters of the RND superfamily
V529_RS08060	COG1033	growth of symbiont in host cell
V529_RS08065	COG0612	Peptidase, M16
V529_RS08070	COG0612	Peptidase, M16
V529_RS08075	COG0300	oxidoreductase activity
V529_RS08090	COG1426	Protein conserved in bacteria
V529_RS08095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
V529_RS08120	COG1692	metallophosphoesterase
V529_RS08125	COG2359	stage V sporulation protein S
V529_RS08145	COG4550	Control of competence regulator ComK, YlbF/YmcA
V529_RS08190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS08195	COG3425	synthase
V529_RS08200	COG1024	Enoyl-CoA hydratase
V529_RS08205	COG1024	Enoyl-CoA hydratase
V529_RS08210	COG3321	synthase
V529_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08210	COG0300	oxidoreductase activity
V529_RS08210	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS08210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08215	COG3321	synthase
V529_RS08215	COG0300	oxidoreductase activity
V529_RS08215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS08215	COG4221	oxidoreductase activity
V529_RS08220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS08220	COG3321	synthase
V529_RS08220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS08220	COG3321	synthase
V529_RS08220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08225	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08225	COG4221	oxidoreductase activity
V529_RS08225	COG3321	synthase
V529_RS08225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
V529_RS08230	COG3321	synthase
V529_RS08230	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
V529_RS08230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS08235	COG2124	cytochrome p450
V529_RS08240	COG3209	COG3209 Rhs family protein
V529_RS08245	COG3619	membrane
V529_RS08255	COG1404	Belongs to the peptidase S8 family
V529_RS08265	COG4195	phage-related replication protein
V529_RS08270	COG1764	response to oxidative stress
V529_RS08280	COG2076	Multidrug Resistance protein
V529_RS08320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V529_RS08325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V529_RS08330	COG4112	unkown
V529_RS08335	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS08345	COG0464	growth
V529_RS08350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
V529_RS08355	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
V529_RS08360	COG0789	Transcriptional regulator
V529_RS08365	COG0174	glutamine synthetase
V529_RS08400	COG2211	Major facilitator Superfamily
V529_RS08405	COG3507	Belongs to the glycosyl hydrolase 43 family
V529_RS08420	COG1070	Carbohydrate kinase
V529_RS08425	COG0574	Belongs to the PEP-utilizing enzyme family
V529_RS08425	COG3848	Pyruvate phosphate dikinase
V529_RS08440	COG2318	DinB family
V529_RS08445	COG1064	alcohol dehydrogenase
V529_RS08450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
V529_RS08450	COG4451	ribulose bisphosphate carboxylase, small
V529_RS08495	COG3397	chitin binding
V529_RS08510	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS08520	COG0756	dUTP diphosphatase activity
V529_RS08525	COG4195	phage-related replication protein
V529_RS08555	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
V529_RS08565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
V529_RS08585	COG0785	Cytochrome C biogenesis protein
V529_RS08590	COG2201	protein-glutamate methylesterase activity
V529_RS08595	COG4846	Membrane protein involved in cytochrome C biogenesis
V529_RS08605	COG0071	Belongs to the small heat shock protein (HSP20) family
V529_RS08620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
V529_RS08625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS08645	COG0824	Thioesterase
V529_RS08655	COG4841	protein insertion into membrane
V529_RS08665	COG1832	CoA-binding protein
V529_RS08670	COG0187	DNA topoisomerase II activity
V529_RS08675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
V529_RS08685	COG1115	amino acid carrier protein
V529_RS08695	COG1063	alcohol dehydrogenase
V529_RS08700	COG0800	Aldolase
V529_RS08705	COG1312	Catalyzes the dehydration of D-mannonate
V529_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08715	COG1609	Transcriptional regulator
V529_RS08720	COG2271	Major facilitator Superfamily
V529_RS08765	COG2205	protein histidine kinase activity
V529_RS08770	COG0745	RESPONSE REGULATOR receiver
V529_RS08780	COG3507	Belongs to the glycosyl hydrolase 43 family
V529_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS08810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
V529_RS08815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
V529_RS08820	COG2610	gluconate transmembrane transporter activity
V529_RS08825	COG2124	cytochrome p450
V529_RS08845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V529_RS08855	COG2246	polysaccharide biosynthetic process
V529_RS08860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
V529_RS08865	COG0586	Pfam SNARE associated Golgi protein
V529_RS08870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
V529_RS08875	COG1024	Enoyl-CoA hydratase
V529_RS08880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
V529_RS08885	COG0511	ligase activity, forming carbon-carbon bonds
V529_RS08890	COG0439	Biotin carboxylase
V529_RS08895	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS08900	COG1960	acyl-CoA dehydrogenase activity
V529_RS08905	COG1649	PFAM Uncharacterised BCR, COG1649
V529_RS08915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08915	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
V529_RS08920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS08940	COG2027	D-alanyl-D-alanine carboxypeptidase
V529_RS08945	COG2017	converts alpha-aldose to the beta-anomer
V529_RS08950	COG0534	Mate efflux family protein
V529_RS08960	COG5444	nuclease activity
V529_RS08975	COG5632	N-Acetylmuramoyl-L-alanine amidase
V529_RS08975	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS08980	COG4824	toxin secretion phage lysis holin
V529_RS09000	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS09005	COG1705	Flagellar rod assembly protein muramidase FlgJ
V529_RS09005	COG1388	LysM domain
V529_RS09080	COG4626	Terminase
V529_RS09080	COG1802	Transcriptional regulator
V529_RS09120	COG0582	viral genome integration into host DNA
V529_RS09125	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
V529_RS09225	COG0582	viral genome integration into host DNA
V529_RS09230	COG0166	Belongs to the GPI family
V529_RS09235	COG0405	Gamma-glutamyltransferase
V529_RS09240	COG2814	Major facilitator Superfamily
V529_RS09245	COG0640	Transcriptional regulator
V529_RS09260	COG0604	alcohol dehydrogenase
V529_RS09265	COG0493	'glutamate synthase
V529_RS09270	COG0070	glutamate synthase
V529_RS09270	COG0067	glutamate synthase
V529_RS09270	COG0069	glutamate synthase activity
V529_RS09275	COG0583	DNA-binding transcription factor activity
V529_RS09280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
V529_RS09295	COG0300	oxidoreductase activity
V529_RS09300	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
V529_RS09310	COG2814	Major facilitator Superfamily
V529_RS09315	COG1070	Carbohydrate kinase
V529_RS09320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
V529_RS09325	COG0243	molybdopterin cofactor binding
V529_RS09355	COG5444	nuclease activity
V529_RS09360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V529_RS09365	COG2207	Transcriptional regulator
V529_RS09365	COG0662	Cupin 2, conserved barrel domain protein
V529_RS09370	COG1309	transcriptional regulator
V529_RS09375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS09385	COG0640	Transcriptional regulator
V529_RS09390	COG0741	lytic transglycosylase activity
V529_RS09395	COG2322	membrane
V529_RS09410	COG1619	proteins homologs of microcin C7 resistance protein MccF
V529_RS09420	COG3584	3D domain protein
V529_RS09420	COG1388	LysM domain
V529_RS09425	COG0514	ATP-dependent DNA helicase (RecQ)
V529_RS09430	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
V529_RS09435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V529_RS09450	COG0071	Belongs to the small heat shock protein (HSP20) family
V529_RS09475	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS09480	COG1657	PFAM Prenyltransferase squalene oxidase
V529_RS09485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
V529_RS09490	COG0733	neurotransmitter:sodium symporter activity
V529_RS09495	COG0385	Bile acid
V529_RS09500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS09505	COG0508	dehydrogenase complex catalyzes the overall conversion of
V529_RS09515	COG4548	von Willebrand factor, type A
V529_RS09520	COG0714	Associated with various cellular activities
V529_RS09525	COG2032	superoxide dismutase activity
V529_RS09530	COG0791	NLP P60 protein
V529_RS09530	COG1388	LysM domain
V529_RS09535	COG1819	glycosyl
V529_RS09540	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
V529_RS09545	COG0534	Mate efflux family protein
V529_RS09550	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS09555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V529_RS09560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V529_RS09570	COG2962	Rard protein
V529_RS09585	COG1942	4-Oxalocrotonate Tautomerase
V529_RS09595	COG1733	regulation of RNA biosynthetic process
V529_RS09600	COG0778	Nitroreductase
V529_RS09605	COG0400	carboxylic ester hydrolase activity
V529_RS09610	COG0346	lactoylglutathione lyase activity
V529_RS09620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
V529_RS09630	COG2723	6-phospho-beta-galactosidase activity
V529_RS09635	COG2188	Transcriptional regulator
V529_RS09640	COG0793	Belongs to the peptidase S41A family
V529_RS09640	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS09645	COG2226	methyltransferase
V529_RS09655	COG1876	peptidase activity
V529_RS09670	COG0671	phosphoesterase, PA-phosphatase related
V529_RS09700	COG1509	lysine 2,3-aminomutase activity
V529_RS09710	COG3331	DNA recombination
V529_RS09740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
V529_RS09780	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
V529_RS09820	COG0756	dUTP diphosphatase activity
V529_RS09835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS09850	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V529_RS09865	COG1372	Participates in initiation and elongation during chromosome replication
V529_RS09865	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V529_RS09870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
V529_RS09875	COG1780	Probably involved in ribonucleotide reductase function
V529_RS09965	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
V529_RS09970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
V529_RS09980	COG3584	3D domain protein
V529_RS09985	COG0587	DNA-directed DNA polymerase activity
V529_RS09990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
V529_RS09995	COG0358	DNA primase activity
V529_RS10000	COG0305	Participates in initiation and elongation during chromosome replication
V529_RS10010	COG2887	Belongs to the helicase family. UvrD subfamily
V529_RS10045	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS10045	COG3420	alginic acid biosynthetic process
V529_RS10050	COG4195	phage-related replication protein
V529_RS10065	COG2135	peptidase activity
V529_RS10070	COG1793	dna ligase
V529_RS10115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
V529_RS10160	COG3655	Transcriptional regulator
V529_RS10255	COG3655	Transcriptional regulator
V529_RS10280	COG3645	SOS response
V529_RS10280	COG3646	Phage regulatory protein
V529_RS10350	COG0776	regulation of translation
V529_RS10485	COG0741	lytic transglycosylase activity
V529_RS10485	COG0739	heme binding
V529_RS10485	COG1196	nuclear chromosome segregation
V529_RS10495	COG2433	Pfam Transposase IS66
V529_RS10510	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS10515	COG5632	N-Acetylmuramoyl-L-alanine amidase
V529_RS10515	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS10540	COG0457	Tetratricopeptide repeat
V529_RS10545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
V529_RS10575	COG5444	nuclease activity
V529_RS10585	COG4282	regulation of fungal-type cell wall biogenesis
V529_RS10590	COG1525	nuclease
V529_RS10595	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
V529_RS10600	COG1509	lysine 2,3-aminomutase activity
V529_RS10605	COG0456	acetyltransferase
V529_RS10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V529_RS10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
V529_RS10620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
V529_RS10625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
V529_RS10630	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
V529_RS10640	COG0456	acetyltransferase
V529_RS10645	COG0463	Glycosyl transferase, family 2
V529_RS10660	COG4641	Protein conserved in bacteria
V529_RS10670	COG1086	Polysaccharide biosynthesis protein
V529_RS10685	COG1846	Transcriptional regulator
V529_RS10690	COG4698	Protein conserved in bacteria
V529_RS10695	COG2755	lipolytic protein G-D-S-L family
V529_RS10700	COG1999	signal sequence binding
V529_RS10710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
V529_RS10715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
V529_RS10720	COG1272	protein, Hemolysin III
V529_RS10725	COG0204	Acyl-transferase
V529_RS10730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
V529_RS10745	COG2136	Putative SAM-dependent methyltransferase
V529_RS10745	COG2521	methyltransferase
V529_RS10760	COG1413	lyase activity
V529_RS10765	COG1418	mRNA catabolic process
V529_RS10770	COG0386	Belongs to the glutathione peroxidase family
V529_RS10780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
V529_RS10785	COG1278	Cold shock
V529_RS10805	COG0328	RNA-DNA hybrid ribonuclease activity
V529_RS10810	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
V529_RS10815	COG0328	RNA-DNA hybrid ribonuclease activity
V529_RS10825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V529_RS10835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
V529_RS10840	COG1755	Isoprenylcysteine carboxyl methyltransferase
V529_RS10845	COG3424	synthase
V529_RS10865	COG2323	membrane
V529_RS10870	COG1335	isochorismatase
V529_RS10910	COG4824	toxin secretion phage lysis holin
V529_RS10930	COG5434	Belongs to the glycosyl hydrolase 28 family
V529_RS10935	COG1705	Flagellar rod assembly protein muramidase FlgJ
V529_RS10945	COG5280	Phage tail tape measure protein TP901
V529_RS10945	COG3953	SLT domain
V529_RS11040	COG1595	DNA-templated transcription, initiation
V529_RS11065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
V529_RS11070	COG1484	DNA-dependent DNA replication
V529_RS11075	COG3935	DnaD domain protein
V529_RS11115	COG3645	SOS response
V529_RS11115	COG3646	Phage regulatory protein
V529_RS11130	COG3620	sequence-specific DNA binding
V529_RS11135	COG0582	viral genome integration into host DNA
V529_RS11140	COG2233	PERMEase
V529_RS11150	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
V529_RS11155	COG1199	ATP-dependent helicase activity
V529_RS11165	COG0116	Belongs to the methyltransferase superfamily
V529_RS11180	COG3359	exonuclease
V529_RS11185	COG1205	dead DEAH box helicase
V529_RS11185	COG1111	helicase
V529_RS11190	COG2190	(PTS) system
V529_RS11195	COG0071	Belongs to the small heat shock protein (HSP20) family
V529_RS11235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V529_RS11235	COG4499	WXG100 protein secretion system (Wss), protein YukC
V529_RS11245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
V529_RS11250	COG3935	DnaD domain protein
V529_RS11260	COG0436	Aminotransferase
V529_RS11265	COG5353	protein conserved in bacteria
V529_RS11270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
V529_RS11270	COG1199	ATP-dependent helicase activity
V529_RS11300	COG0438	transferase activity, transferring glycosyl groups
V529_RS11305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V529_RS11320	COG1694	Mazg nucleotide pyrophosphohydrolase
V529_RS11325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS11330	COG2140	Oxalate decarboxylase
V529_RS11340	COG4347	Protein of unknown function (DUF1405)
V529_RS11345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
V529_RS11345	COG2010	Cytochrome c
V529_RS11350	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
V529_RS11355	COG0723	plastoquinol--plastocyanin reductase activity
V529_RS11370	COG0457	Tetratricopeptide repeat
V529_RS11380	COG0287	Prephenate dehydrogenase
V529_RS11415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
V529_RS11420	COG4401	Chorismate mutase type I
V529_RS11435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
V529_RS11440	COG0105	UTP biosynthetic process
V529_RS11445	COG0142	geranyltranstransferase activity
V529_RS11455	COG0142	geranyltranstransferase activity
V529_RS11470	COG0776	regulation of translation
V529_RS11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
V529_RS11510	COG0539	negative regulation of cytoplasmic translation
V529_RS11520	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
V529_RS11525	COG2959	enzyme of heme biosynthesis
V529_RS11530	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS11530	COG3773	Cell wall hydrolase
V529_RS11535	COG2339	peptidase activity
V529_RS11540	COG0492	ferredoxin-NADP+ reductase activity
V529_RS11545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V529_RS11550	COG4862	establishment of competence for transformation
V529_RS11555	COG1408	metallophosphoesterase
V529_RS11565	COG1388	LysM domain
V529_RS11570	COG1266	CAAX protease self-immunity
V529_RS11575	COG0514	ATP-dependent DNA helicase (RecQ)
V529_RS11580	COG4955	Helix-turn-helix domain
V529_RS11585	COG1141	Ferredoxin
V529_RS11590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
V529_RS11595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
V529_RS11605	COG1595	DNA-templated transcription, initiation
V529_RS11610	COG5002	protein histidine kinase activity
V529_RS11615	COG0745	RESPONSE REGULATOR receiver
V529_RS11620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
V529_RS11625	COG1333	cytochrome c biogenesis protein
V529_RS11630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS11635	COG1187	pseudouridine synthase activity
V529_RS11640	COG0700	Nucleoside recognition
V529_RS11645	COG2715	membrane protein required for spore maturation
V529_RS11650	COG1686	Belongs to the peptidase S11 family
V529_RS11670	COG1547	Domain of unknown function (DUF309)
V529_RS11675	COG0456	acetyltransferase
V529_RS11690	COG0307	riboflavin synthase, alpha
V529_RS11695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
V529_RS11695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
V529_RS11705	COG0681	Belongs to the peptidase S26 family
V529_RS11715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
V529_RS11720	COG4086	secreted protein
V529_RS11725	COG0019	diaminopimelate decarboxylase activity
V529_RS11730	COG0697	spore germination
V529_RS11745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
V529_RS11765	COG1191	sigma factor activity
V529_RS11775	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS11780	COG1686	Belongs to the peptidase S11 family
V529_RS11785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
V529_RS11790	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
V529_RS11795	COG4974	Belongs to the 'phage' integrase family
V529_RS11805	COG0735	belongs to the Fur family
V529_RS11810	COG1300	Membrane
V529_RS11825	COG0281	malic enzyme
V529_RS11830	COG1757	Na H antiporter
V529_RS11835	COG1027	Aspartate ammonia-lyase
V529_RS11840	COG0252	asparaginase activity
V529_RS11845	COG1396	sequence-specific DNA binding
V529_RS11850	COG1379	DNA repair
V529_RS11855	COG0494	nUDIX hydrolase
V529_RS11865	COG0667	Aldo Keto reductase
V529_RS11875	COG1073	alpha beta
V529_RS11885	COG4918	Iron-sulphur cluster biosynthesis
V529_RS11890	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
V529_RS11890	COG0456	acetyltransferase
V529_RS11895	COG2329	Antibiotic biosynthesis monooxygenase
V529_RS11900	COG0456	acetyltransferase
V529_RS11905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
V529_RS11920	COG0628	permease
V529_RS11925	COG0346	lactoylglutathione lyase activity
V529_RS11935	COG3048	D-serine ammonia-lyase activity
V529_RS11940	COG0300	oxidoreductase activity
V529_RS11945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS11950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
V529_RS11955	COG1024	Enoyl-CoA hydratase
V529_RS11960	COG3425	synthase
V529_RS11965	COG2124	cytochrome p450
V529_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS11970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS11970	COG3321	synthase
V529_RS11970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS11975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11975	COG3321	synthase
V529_RS11975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS11980	COG3321	synthase
V529_RS11980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS11980	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11980	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS11980	COG0300	oxidoreductase activity
V529_RS11985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS11985	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS11985	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11985	COG0300	oxidoreductase activity
V529_RS11985	COG3321	synthase
V529_RS11990	COG3321	synthase
V529_RS11990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS11990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS11995	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS11995	COG0300	oxidoreductase activity
V529_RS11995	COG3321	synthase
V529_RS11995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS12000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS12000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS12000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS12000	COG3321	synthase
V529_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS12010	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS12025	COG2070	2-Nitropropane dioxygenase
V529_RS12025	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
V529_RS12030	COG0250	Participates in transcription elongation, termination and antitermination
V529_RS12050	COG0596	Alpha beta hydrolase
V529_RS12065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
V529_RS12070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
V529_RS12085	COG0706	membrane insertase activity
V529_RS12090	COG2195	Cleaves the N-terminal amino acid of tripeptides
V529_RS12095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
V529_RS12100	COG0346	lactoylglutathione lyase activity
V529_RS12105	COG1376	ErfK ybiS ycfS ynhG family protein
V529_RS12110	COG4129	membrane
V529_RS12115	COG1126	abc transporter atp-binding protein
V529_RS12120	COG0765	amino acid transport
V529_RS12125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS12135	COG1597	lipid kinase activity
V529_RS12140	COG0508	dehydrogenase complex catalyzes the overall conversion of
V529_RS12145	COG0022	dehydrogenase e1 component
V529_RS12150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
V529_RS12155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
V529_RS12160	COG3426	butyrate kinase activity
V529_RS12165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V529_RS12170	COG0280	phosphate acetyltransferase
V529_RS12175	COG3829	transcription factor binding
V529_RS12175	COG3290	protein histidine kinase activity
V529_RS12185	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
V529_RS12190	COG2079	MmgE PrpD family protein
V529_RS12195	COG0372	Belongs to the citrate synthase family
V529_RS12200	COG1960	acyl-CoA dehydrogenase activity
V529_RS12205	COG1250	3-hydroxyacyl-CoA dehydrogenase
V529_RS12210	COG0183	Belongs to the thiolase family
V529_RS12215	COG0584	glycerophosphoryl diester phosphodiesterase
V529_RS12220	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS12245	COG1902	pentaerythritol trinitrate reductase activity
V529_RS12260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
V529_RS12265	COG0745	RESPONSE REGULATOR receiver
V529_RS12270	COG0750	zinc metalloprotease
V529_RS12275	COG0497	DNA recombination
V529_RS12285	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
V529_RS12295	COG0142	geranyltranstransferase activity
V529_RS12305	COG1570	exodeoxyribonuclease VII activity
V529_RS12320	COG1302	Protein conserved in bacteria
V529_RS12325	COG0439	Biotin carboxylase
V529_RS12330	COG0511	ligase activity, forming carbon-carbon bonds
V529_RS12370	COG3854	ATPases associated with a variety of cellular activities
V529_RS12385	COG0006	proline dipeptidase activity
V529_RS12395	COG3872	metal-dependent enzyme
V529_RS12405	COG1752	Esterase of the alpha-beta hydrolase superfamily
V529_RS12420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
V529_RS12440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
V529_RS12455	COG1396	sequence-specific DNA binding
V529_RS12465	COG0681	Belongs to the peptidase S26 family
V529_RS12490	COG4940	Competence protein ComGF
V529_RS12500	COG4970	Tfp pilus assembly protein FimT
V529_RS12505	COG4537	Required for transformation and DNA binding
V529_RS12510	COG1459	type II secretion system
V529_RS12515	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
V529_RS12520	COG0598	Magnesium transport protein CorA
V529_RS12525	COG1253	flavin adenine dinucleotide binding
V529_RS12530	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS12540	COG1393	Belongs to the ArsC family
V529_RS12550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS12560	COG0011	TIGRFAM Protein of
V529_RS12570	COG2866	Carboxypeptidase
V529_RS12575	COG1940	carbohydrate kinase activity
V529_RS12580	COG4483	Protein conserved in bacteria
V529_RS12585	COG1757	Na H antiporter
V529_RS12590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
V529_RS12600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
V529_RS12605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V529_RS12610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
V529_RS12615	COG0581	inorganic phosphate transmembrane transporter activity
V529_RS12620	COG0573	inorganic phosphate transmembrane transporter activity
V529_RS12625	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
V529_RS12630	COG0768	penicillin binding
V529_RS12635	COG0477	Major facilitator Superfamily
V529_RS12640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
V529_RS12645	COG2839	Protein conserved in bacteria
V529_RS12650	COG5521	maltodextrose utilization protein MalA
V529_RS12655	COG1388	LysM domain
V529_RS12665	COG4709	membrane
V529_RS12670	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
V529_RS12675	COG0735	belongs to the Fur family
V529_RS12680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS12695	COG0513	Belongs to the DEAD box helicase family
V529_RS12710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
V529_RS12715	COG2384	SAM-dependent methyltransferase
V529_RS12720	COG2010	Cytochrome c
V529_RS12725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
V529_RS12730	COG0358	DNA primase activity
V529_RS12745	COG0517	IMP dehydrogenase activity
V529_RS12750	COG0751	glycine-tRNA ligase activity
V529_RS12765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
V529_RS12770	COG0295	cytidine deaminase activity
V529_RS12775	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
V529_RS12785	COG1480	7TM receptor with intracellular HD hydrolase
V529_RS12790	COG1702	phosphate starvation-inducible protein PhoH
V529_RS12795	COG0561	phosphatase activity
V529_RS12810	COG4864	UPF0365 protein
V529_RS12815	COG1030	water channel activity
V529_RS12820	COG1610	YqeY-like protein
V529_RS12830	COG1283	sodium-dependent phosphate transmembrane transporter activity
V529_RS12835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
V529_RS12840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
V529_RS12870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
V529_RS12885	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS12900	COG1466	dna polymerase III delta subunit
V529_RS12910	COG0658	competence protein
V529_RS12910	COG2333	competence protein COMEC
V529_RS12915	COG2131	deaminase
V529_RS12920	COG1596	polysaccharide export
V529_RS12920	COG1555	photosystem II stabilization
V529_RS12925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
V529_RS12930	COG2226	methyltransferase
V529_RS12935	COG0799	negative regulation of ribosome biogenesis
V529_RS12940	COG1713	HD superfamily hydrolase involved in NAD metabolism
V529_RS12950	COG1534	Rna-binding protein
V529_RS12955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
V529_RS12960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
V529_RS12965	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
V529_RS12975	COG2755	lipolytic protein G-D-S-L family
V529_RS12985	COG0398	Pfam SNARE associated Golgi protein
V529_RS13005	COG3628	GPW Gp25 family protein
V529_RS13010	COG1794	racemase activity, acting on amino acids and derivatives
V529_RS13035	COG0642	Histidine kinase
V529_RS13035	COG5002	protein histidine kinase activity
V529_RS13040	COG0745	RESPONSE REGULATOR receiver
V529_RS13045	COG2311	Membrane
V529_RS13050	COG0454	-acetyltransferase
V529_RS13055	COG0563	adenylate kinase activity
V529_RS13065	COG2814	Major facilitator Superfamily
V529_RS13070	COG0456	acetyltransferase
V529_RS13075	COG2318	DinB family
V529_RS13085	COG0561	phosphatase activity
V529_RS13090	COG0561	phosphatase activity
V529_RS13100	COG1482	cell wall glycoprotein biosynthetic process
V529_RS13105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS13105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V529_RS13105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
V529_RS13110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS13110	COG3711	transcriptional antiterminator
V529_RS13120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
V529_RS13125	COG0583	DNA-binding transcription factor activity
V529_RS13130	COG2814	Major facilitator Superfamily
V529_RS13135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V529_RS13135	COG2124	cytochrome p450
V529_RS13140	COG1309	transcriptional regulator
V529_RS13145	COG2226	methyltransferase
V529_RS13155	COG2116	formate transmembrane transporter activity
V529_RS13160	COG5609	conserved protein (DUF2294)
V529_RS13165	COG3383	formate dehydrogenase (NAD+) activity
V529_RS13170	COG2427	Protein of unknown function (DUF1641)
V529_RS13180	COG0626	cystathionine gamma-synthase activity
V529_RS13185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V529_RS13210	COG0768	penicillin binding
V529_RS13225	COG0826	peptidase U32
V529_RS13230	COG0826	peptidase U32
V529_RS13235	COG4122	O-methyltransferase activity
V529_RS13240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
V529_RS13265	COG0628	permease
V529_RS13270	COG1126	abc transporter atp-binding protein
V529_RS13275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS13280	COG0765	amino acid transport
V529_RS13285	COG0765	amino acid transport
V529_RS13295	COG3881	PFAM PRC-barrel domain
V529_RS13300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
V529_RS13305	COG0457	Tetratricopeptide repeat
V529_RS13315	COG1104	cysteine desulfurase activity
V529_RS13320	COG1959	2 iron, 2 sulfur cluster binding
V529_RS13325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
V529_RS13330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
V529_RS13345	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS13345	COG4991	sh3 domain protein
V529_RS13345	COG3103	Sh3 type 3 domain protein
V529_RS13355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
V529_RS13365	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
V529_RS13365	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
V529_RS13370	COG5416	Lipopolysaccharide assembly protein A domain
V529_RS13375	COG0490	domain, Protein
V529_RS13380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
V529_RS13380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
V529_RS13390	COG2244	polysaccharide biosynthetic process
V529_RS13395	COG2323	membrane
V529_RS13405	COG1862	Preprotein translocase
V529_RS13450	COG1388	LysM domain
V529_RS13460	COG0157	Belongs to the NadC ModD family
V529_RS13465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
V529_RS13470	COG1104	cysteine desulfurase activity
V529_RS13475	COG1827	regulation of RNA biosynthetic process
V529_RS13480	COG0077	Prephenate dehydratase
V529_RS13495	COG3290	protein histidine kinase activity
V529_RS13500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
V529_RS13505	COG2868	ribosomal protein
V529_RS13515	COG1994	Peptidase M50
V529_RS13520	COG0739	heme binding
V529_RS13525	COG2894	cell division
V529_RS13535	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
V529_RS13545	COG1077	Cell shape determining protein MreB Mrl
V529_RS13565	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
V529_RS13570	COG0285	dihydrofolate synthase activity
V529_RS13575	COG0525	valine-tRNA ligase activity
V529_RS13585	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V529_RS13590	COG1388	LysM domain
V529_RS13600	COG0113	porphobilinogen synthase activity
V529_RS13605	COG1587	Uroporphyrinogen-III synthase
V529_RS13615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
V529_RS13635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
V529_RS13640	COG1067	ATP-dependent peptidase activity
V529_RS13640	COG0470	DNA polymerase III
V529_RS13655	COG1477	protein flavinylation
V529_RS13655	COG0457	Tetratricopeptide repeat
V529_RS13670	COG0473	3-isopropylmalate dehydrogenase activity
V529_RS13685	COG0440	acetolactate synthase activity
V529_RS13690	COG0028	Belongs to the TPP enzyme family
V529_RS13715	COG0622	Phosphoesterase
V529_RS13720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
V529_RS13730	COG5401	PFAM Sporulation and spore germination
V529_RS13740	COG1846	Transcriptional regulator
V529_RS13745	COG2197	response regulator
V529_RS13750	COG0824	Thioesterase
V529_RS13755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
V529_RS13760	COG1053	succinate dehydrogenase
V529_RS13765	COG2009	succinate dehydrogenase
V529_RS13770	COG1719	4-vinyl reductase, 4VR
V529_RS13775	COG0527	aspartate kinase activity
V529_RS13785	COG3118	belongs to the thioredoxin family
V529_RS13790	COG3534	alpha-L-arabinofuranosidase
V529_RS13795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
V529_RS13800	COG2086	electron transfer activity
V529_RS13805	COG1024	Enoyl-CoA hydratase
V529_RS13810	COG1309	transcriptional regulator
V529_RS13815	COG0318	PFAM AMP-dependent synthetase and ligase
V529_RS13825	COG3766	membrane
V529_RS13835	COG1796	DNA polymerase
V529_RS13835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
V529_RS13840	COG1286	toxin biosynthetic process
V529_RS13855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V529_RS13855	COG0072	phenylalanine-tRNA ligase activity
V529_RS13860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
V529_RS13865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
V529_RS13875	COG3835	regulator
V529_RS13880	COG0277	FAD linked oxidase domain protein
V529_RS13885	COG0247	lactate metabolic process
V529_RS13890	COG1966	Carbon starvation protein
V529_RS13895	COG3534	alpha-L-arabinofuranosidase
V529_RS13900	COG0395	ABC-type sugar transport system, permease component
V529_RS13905	COG1175	transmembrane transport
V529_RS13910	COG1653	transport
V529_RS13920	COG0647	UMP catabolic process
V529_RS13925	COG0235	Class ii aldolase
V529_RS13930	COG1069	ribulokinase activity
V529_RS13935	COG2160	L-arabinose isomerase activity
V529_RS13940	COG3507	Belongs to the glycosyl hydrolase 43 family
V529_RS13945	COG1363	Peptidase, m42
V529_RS13955	COG3326	Membrane
V529_RS13970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
V529_RS13975	COG1346	cytolysis
V529_RS13980	COG1380	Effector of murein hydrolase LrgA
V529_RS13985	COG3279	Response regulator of the LytR AlgR family
V529_RS13990	COG3275	phosphorelay sensor kinase activity
V529_RS13995	COG1011	Hydrolase
V529_RS14010	COG0398	Pfam SNARE associated Golgi protein
V529_RS14015	COG1484	DNA-dependent DNA replication
V529_RS14020	COG3611	Membrane attachment protein
V529_RS14035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
V529_RS14040	COG1733	regulation of RNA biosynthetic process
V529_RS14045	COG2814	Major facilitator Superfamily
V529_RS14050	COG0656	L-ascorbic acid biosynthetic process
V529_RS14055	COG0237	dephospho-CoA kinase activity
V529_RS14060	COG1971	Probably functions as a manganese efflux pump
V529_RS14065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
V529_RS14070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V529_RS14070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
V529_RS14075	COG5002	protein histidine kinase activity
V529_RS14080	COG0745	RESPONSE REGULATOR receiver
V529_RS14090	COG0538	isocitrate dehydrogenase activity
V529_RS14095	COG0372	Belongs to the citrate synthase family
V529_RS14110	COG0628	permease
V529_RS14115	COG3030	protein affecting phage T7 exclusion by the F plasmid
V529_RS14120	COG0469	pyruvate kinase activity
V529_RS14145	COG0281	malic enzyme
V529_RS14150	COG0587	DNA-directed DNA polymerase activity
V529_RS14170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
V529_RS14180	COG4109	DRTGG domain
V529_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS14205	COG0521	Mo-molybdopterin cofactor biosynthetic process
V529_RS14215	COG0827	DNA restriction-modification system
V529_RS14220	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
V529_RS14225	COG3874	Sporulation protein YtfJ
V529_RS14235	COG1714	RDD family
V529_RS14240	COG0616	signal peptide processing
V529_RS14245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
V529_RS14250	COG1574	metal-dependent hydrolase with the TIM-barrel fold
V529_RS14255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
V529_RS14270	COG1104	cysteine desulfurase activity
V529_RS14275	COG1114	Component of the transport system for branched-chain amino acids
V529_RS14285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
V529_RS14290	COG1309	transcriptional regulator
V529_RS14295	COG1956	GAF domain-containing protein
V529_RS14300	COG2203	Gaf domain
V529_RS14300	COG2199	diguanylate cyclase activity
V529_RS14310	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS14315	COG4282	regulation of fungal-type cell wall biogenesis
V529_RS14320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
V529_RS14320	COG1017	nitric oxide dioxygenase activity
V529_RS14330	COG0693	protein deglycase activity
V529_RS14345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
V529_RS14350	COG1378	Sugar-specific transcriptional regulator TrmB
V529_RS14370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
V529_RS14375	COG0454	-acetyltransferase
V529_RS14380	COG0517	IMP dehydrogenase activity
V529_RS14385	COG0123	including yeast histone deacetylase and acetoin utilization protein
V529_RS14390	COG1360	Flagellar Motor Protein
V529_RS14395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
V529_RS14400	COG1609	Transcriptional regulator
V529_RS14405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
V529_RS14405	COG1605	Chorismate mutase
V529_RS14410	COG3118	belongs to the thioredoxin family
V529_RS14415	COG4980	gas vesicle protein
V529_RS14420	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
V529_RS14430	COG1674	ftsk spoiiie
V529_RS14435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
V529_RS14445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS14455	COG1363	Peptidase, m42
V529_RS14460	COG5584	Small secreted protein
V529_RS14465	COG0281	malic enzyme
V529_RS14470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
V529_RS14485	COG0510	thiamine kinase activity
V529_RS14490	COG1597	lipid kinase activity
V529_RS14500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
V529_RS14505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
V529_RS14510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V529_RS14515	COG2252	PERMEase
V529_RS14520	COG4473	ABC transporter
V529_RS14525	COG1131	(ABC) transporter
V529_RS14530	COG1349	DNA-binding transcription factor activity
V529_RS14535	COG1187	pseudouridine synthase activity
V529_RS14540	COG2244	polysaccharide biosynthetic process
V529_RS14545	COG2081	HI0933 family
V529_RS14550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
V529_RS14560	COG1609	Transcriptional regulator
V529_RS14565	COG1653	transport
V529_RS14570	COG1175	transmembrane transport
V529_RS14575	COG0395	ABC-type sugar transport system, permease component
V529_RS14580	COG1486	melibiose metabolic process
V529_RS14590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
V529_RS14605	COG1366	Belongs to the anti-sigma-factor antagonist family
V529_RS14605	COG2202	Pas domain
V529_RS14610	COG2814	Major facilitator Superfamily
V529_RS14615	COG5522	Integral membrane protein (intg_mem_TP0381)
V529_RS14620	COG0577	efflux transmembrane transporter activity
V529_RS14625	COG1136	(ABC) transporter
V529_RS14630	COG2205	protein histidine kinase activity
V529_RS14635	COG0745	RESPONSE REGULATOR receiver
V529_RS14640	COG0577	efflux transmembrane transporter activity
V529_RS14645	COG1136	(ABC) transporter
V529_RS14665	COG1131	(ABC) transporter
V529_RS14670	COG1725	Transcriptional regulator
V529_RS14680	COG1242	4 iron, 4 sulfur cluster binding
V529_RS14685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
V529_RS14700	COG2267	carboxylic ester hydrolase activity
V529_RS14705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
V529_RS14710	COG1113	amino acid transport
V529_RS14715	COG0367	asparagine synthase
V529_RS14735	COG1506	peptidase
V529_RS14740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
V529_RS14745	COG1116	anion transmembrane transporter activity
V529_RS14750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
V529_RS14755	COG0494	nUDIX hydrolase
V529_RS14760	COG4824	toxin secretion phage lysis holin
V529_RS14765	COG0783	Belongs to the Dps family
V529_RS14790	COG0288	reversible hydration of carbon dioxide
V529_RS14800	COG1271	oxidase subunit
V529_RS14805	COG1294	oxidase, subunit
V529_RS14810	COG4948	Mandelate Racemase Muconate Lactonizing
V529_RS14820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
V529_RS14825	COG0596	Alpha beta hydrolase
V529_RS14835	COG1169	isochorismate synthase
V529_RS14840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
V529_RS14845	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
V529_RS14970	COG3859	Proton-coupled thiamine transporter YuaJ
V529_RS14975	COG2268	Band 7 protein
V529_RS14980	COG1585	Membrane protein implicated in regulation of membrane protease activity
V529_RS14985	COG2318	DinB family
V529_RS14995	COG1454	alcohol dehydrogenase
V529_RS15000	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS15005	COG1510	regulation of RNA biosynthetic process
V529_RS15015	COG0569	domain protein
V529_RS15020	COG1705	Flagellar rod assembly protein muramidase FlgJ
V529_RS15025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
V529_RS15025	COG1017	nitric oxide dioxygenase activity
V529_RS15050	COG0628	permease
V529_RS15055	COG0673	inositol 2-dehydrogenase activity
V529_RS15060	COG0693	protein deglycase activity
V529_RS15065	COG0840	transmembrane signaling receptor activity
V529_RS15070	COG0840	transmembrane signaling receptor activity
V529_RS15075	COG0840	transmembrane signaling receptor activity
V529_RS15080	COG0840	transmembrane signaling receptor activity
V529_RS15095	COG2070	2-Nitropropane dioxygenase
V529_RS15100	COG0432	Pfam Uncharacterised protein family UPF0047
V529_RS15105	COG0366	Alpha amylase catalytic
V529_RS15110	COG1253	flavin adenine dinucleotide binding
V529_RS15115	COG2738	Putative neutral zinc metallopeptidase
V529_RS15130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
V529_RS15155	COG1335	isochorismatase
V529_RS15160	COG1979	alcohol dehydrogenase
V529_RS15165	COG1979	alcohol dehydrogenase
V529_RS15170	COG2155	Conserved Protein
V529_RS15175	COG1098	S1 RNA binding domain
V529_RS15180	COG0436	Aminotransferase
V529_RS15185	COG1522	sequence-specific DNA binding
V529_RS15190	COG2267	carboxylic ester hydrolase activity
V529_RS15200	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
V529_RS15205	COG2205	protein histidine kinase activity
V529_RS15215	COG5018	Exonuclease
V529_RS15220	COG2814	Major facilitator Superfamily
V529_RS15225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V529_RS15230	COG3011	Protein conserved in bacteria
V529_RS15240	COG3290	protein histidine kinase activity
V529_RS15245	COG4565	transcriptional regulatory protein
V529_RS15250	COG1744	ABC transporter substrate-binding protein PnrA-like
V529_RS15255	COG3845	ABC transporter
V529_RS15260	COG4603	Belongs to the binding-protein-dependent transport system permease family
V529_RS15265	COG1079	Belongs to the binding-protein-dependent transport system permease family
V529_RS15275	COG2111	Na H antiporter
V529_RS15275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
V529_RS15280	COG2111	Na H antiporter
V529_RS15285	COG1006	Multisubunit Na H antiporter MnhC subunit
V529_RS15290	COG0651	ATP synthesis coupled electron transport
V529_RS15295	COG1863	multisubunit Na H antiporter MnhE subunit
V529_RS15300	COG2212	antiporter activity
V529_RS15305	COG1320	monovalent cation:proton antiporter activity
V529_RS15310	COG2050	protein possibly involved in aromatic compounds catabolism
V529_RS15315	COG2197	response regulator
V529_RS15320	COG4585	Histidine kinase
V529_RS15330	COG0142	geranyltranstransferase activity
V529_RS15345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
V529_RS15350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
V529_RS15355	COG1335	isochorismatase
V529_RS15360	COG5506	Protein of unknown function (DUF1694)
V529_RS15375	COG0628	permease
V529_RS15385	COG1418	mRNA catabolic process
V529_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS15400	COG1511	domain protein
V529_RS15405	COG1674	ftsk spoiiie
V529_RS15405	COG0433	COG0433 Predicted ATPase
V529_RS15410	COG4499	WXG100 protein secretion system (Wss), protein YukC
V529_RS15415	COG5417	Belongs to the EsaB family
V529_RS15420	COG4842	Belongs to the WXG100 family
V529_RS15425	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
V529_RS15425	COG2508	Transcriptional regulator
V529_RS15430	COG0686	Belongs to the AlaDH PNT family
V529_RS15435	COG5634	Uncharacterized conserved protein (DUF2278)
V529_RS15440	COG3251	PFAM MbtH domain protein
V529_RS15445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS15450	COG1535	isochorismatase
V529_RS15450	COG3433	isochorismatase activity
V529_RS15455	COG1021	2,3-dihydroxybenzoate-AMP ligase
V529_RS15460	COG1169	isochorismate synthase
V529_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS15470	COG2819	hydrolase of the alpha beta superfamily
V529_RS15475	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
V529_RS15480	COG1268	BioY protein
V529_RS15485	COG2056	Na+-H+ antiporter family
V529_RS15495	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
V529_RS15500	COG3584	3D domain protein
V529_RS15515	COG1252	NADH dehydrogenase
V529_RS15545	COG1131	(ABC) transporter
V529_RS15565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
V529_RS15570	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
V529_RS15575	COG0316	Belongs to the HesB IscA family
V529_RS15585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V529_RS15595	COG1252	NADH dehydrogenase
V529_RS15600	COG4837	Protein of unknown function (DUF1462)
V529_RS15605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
V529_RS15610	COG4946	Tricorn protease homolog
V529_RS15610	COG1506	peptidase
V529_RS15610	COG0823	Involved in the tonB-independent uptake of proteins
V529_RS15620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
V529_RS15625	COG0460	homoserine dehydrogenase
V529_RS15630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
V529_RS15635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
V529_RS15640	COG0647	UMP catabolic process
V529_RS15645	COG2445	Protein of unknown function DUF86
V529_RS15650	COG4470	Protein conserved in bacteria
V529_RS15660	COG0739	heme binding
V529_RS15670	COG0737	Belongs to the 5'-nucleotidase family
V529_RS15675	COG0730	response to heat
V529_RS15680	COG1801	Protein of unknown function DUF72
V529_RS15695	COG2508	Transcriptional regulator
V529_RS15700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
V529_RS15715	COG2814	Major facilitator Superfamily
V529_RS15720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
V529_RS15725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
V529_RS15730	COG2356	endonuclease I
V529_RS15735	COG3842	ATPase activity
V529_RS15740	COG2188	Transcriptional regulator
V529_RS15745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V529_RS15750	COG0395	ABC-type sugar transport system, permease component
V529_RS15755	COG1175	transmembrane transport
V529_RS15760	COG1653	transport
V529_RS15765	COG2222	sugar isomerase
V529_RS15775	COG0322	excinuclease ABC activity
V529_RS15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
V529_RS15785	COG2226	methyltransferase
V529_RS15795	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS15800	COG0719	Fe-S assembly protein
V529_RS15805	COG0822	iron-sulfur transferase activity
V529_RS15810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
V529_RS15815	COG0719	Fe-S assembly protein
V529_RS15820	COG0396	ATPase activity
V529_RS15825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
V529_RS15830	COG1464	Belongs to the NlpA lipoprotein family
V529_RS15835	COG2011	ABC-type metal ion transport system permease component
V529_RS15840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
V529_RS15850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
V529_RS15855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
V529_RS15870	COG1393	Belongs to the ArsC family
V529_RS15875	COG1960	acyl-CoA dehydrogenase activity
V529_RS15880	COG0183	Belongs to the thiolase family
V529_RS15885	COG1024	Enoyl-CoA hydratase
V529_RS15885	COG1250	3-hydroxyacyl-CoA dehydrogenase
V529_RS15905	COG5577	PFAM Coat F domain
V529_RS15910	COG1846	Transcriptional regulator
V529_RS15915	COG0477	Major facilitator Superfamily
V529_RS15920	COG0583	DNA-binding transcription factor activity
V529_RS15940	COG1120	ATPase activity
V529_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS15960	COG0783	Belongs to the Dps family
V529_RS15965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V529_RS15970	COG0745	RESPONSE REGULATOR receiver
V529_RS15975	COG2770	Histidine kinase
V529_RS15975	COG2205	protein histidine kinase activity
V529_RS15980	COG1309	transcriptional regulator
V529_RS15985	COG0114	fumarate hydratase activity
V529_RS15995	COG0697	spore germination
V529_RS16000	COG0814	amino acid
V529_RS16010	COG2197	response regulator
V529_RS16015	COG4585	Histidine kinase
V529_RS16020	COG4758	membrane
V529_RS16025	COG3595	metallopeptidase activity
V529_RS16030	COG1842	Phage shock protein A
V529_RS16035	COG4758	membrane
V529_RS16040	COG2814	Major facilitator Superfamily
V529_RS16045	COG2096	Adenosyltransferase
V529_RS16050	COG1120	ATPase activity
V529_RS16055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS16060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V529_RS16065	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS16070	COG3386	PFAM SMP-30 Gluconolaconase
V529_RS16075	COG2205	protein histidine kinase activity
V529_RS16080	COG0745	RESPONSE REGULATOR receiver
V529_RS16090	COG1191	sigma factor activity
V529_RS16095	COG2140	Oxalate decarboxylase
V529_RS16105	COG1120	ATPase activity
V529_RS16110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS16115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS16120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V529_RS16125	COG0531	amino acid
V529_RS16135	COG1988	membrane-bound metal-dependent
V529_RS16140	COG1368	sulfuric ester hydrolase activity
V529_RS16145	COG1910	domain protein
V529_RS16150	COG0725	ABC transporter, periplasmic molybdate-binding protein
V529_RS16155	COG4149	molybdate abc transporter
V529_RS16160	COG2197	response regulator
V529_RS16165	COG3850	Histidine kinase
V529_RS16170	COG1131	(ABC) transporter
V529_RS16180	COG0842	Transport permease protein
V529_RS16185	COG0656	L-ascorbic acid biosynthetic process
V529_RS16210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
V529_RS16215	COG3973	AAA domain
V529_RS16220	COG2860	membrane
V529_RS16230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
V529_RS16235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
V529_RS16240	COG2217	Heavy metal translocating P-type atpase
V529_RS16245	COG2217	Heavy metal translocating P-type atpase
V529_RS16250	COG2608	mercury ion transmembrane transporter activity
V529_RS16255	COG1937	Protein conserved in bacteria
V529_RS16260	COG0673	inositol 2-dehydrogenase activity
V529_RS16270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS16275	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
V529_RS16280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS16285	COG1126	abc transporter atp-binding protein
V529_RS16290	COG0765	amino acid transport
V529_RS16295	COG0765	amino acid transport
V529_RS16300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS16305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
V529_RS16310	COG0454	-acetyltransferase
V529_RS16315	COG0583	DNA-binding transcription factor activity
V529_RS16320	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS16325	COG2732	(Barnase) inhibitor
V529_RS16335	COG2732	(Barnase) inhibitor
V529_RS16345	COG0557	exoribonuclease II activity
V529_RS16350	COG1647	Serine aminopeptidase, S33
V529_RS16355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
V529_RS16360	COG1476	TRANSCRIPTIONal
V529_RS16365	COG1396	sequence-specific DNA binding
V529_RS16370	COG1396	sequence-specific DNA binding
V529_RS16375	COG1733	regulation of RNA biosynthetic process
V529_RS16400	COG1131	(ABC) transporter
V529_RS16405	COG1174	glycine betaine transport
V529_RS16410	COG1732	Glycine betaine
V529_RS16415	COG1174	glycine betaine transport
V529_RS16420	COG0517	IMP dehydrogenase activity
V529_RS16420	COG1125	glycine betaine transport
V529_RS16425	COG1510	regulation of RNA biosynthetic process
V529_RS16430	COG1174	glycine betaine transport
V529_RS16435	COG1732	Glycine betaine
V529_RS16440	COG1174	glycine betaine transport
V529_RS16445	COG0517	IMP dehydrogenase activity
V529_RS16445	COG1125	glycine betaine transport
V529_RS16450	COG1510	regulation of RNA biosynthetic process
V529_RS16455	COG2095	MarC family integral membrane protein
V529_RS16460	COG3064	Membrane
V529_RS16465	COG4640	response to antibiotic
V529_RS16470	COG0456	acetyltransferase
V529_RS16485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
V529_RS16505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS16510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V529_RS16520	COG2234	aminopeptidase activity
V529_RS16540	COG0126	phosphoglycerate kinase activity
V529_RS16550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
V529_RS16555	COG2390	Transcriptional regulator
V529_RS16560	COG2814	Major facilitator Superfamily
V529_RS16565	COG1609	Transcriptional regulator
V529_RS16570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS16580	COG0583	DNA-binding transcription factor activity
V529_RS16585	COG0697	spore germination
V529_RS16590	COG1113	amino acid transport
V529_RS16600	COG1609	Transcriptional regulator
V529_RS16610	COG0561	phosphatase activity
V529_RS16615	COG1737	Transcriptional regulator
V529_RS16620	COG1070	Carbohydrate kinase
V529_RS16645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V529_RS16650	COG2186	Transcriptional regulator
V529_RS16655	COG1620	l-lactate permease
V529_RS16660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
V529_RS16670	COG5039	Polysaccharide pyruvyl transferase
V529_RS16675	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V529_RS16680	COG0110	maltose O-acetyltransferase activity
V529_RS16685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
V529_RS16690	COG2244	polysaccharide biosynthetic process
V529_RS16695	COG1216	Glycosyl transferase, family 2
V529_RS16700	COG5039	Polysaccharide pyruvyl transferase
V529_RS16705	COG1216	Glycosyl transferase, family 2
V529_RS16715	COG0438	transferase activity, transferring glycosyl groups
V529_RS16720	COG1215	transferase activity, transferring glycosyl groups
V529_RS16725	COG0438	transferase activity, transferring glycosyl groups
V529_RS16730	COG1086	Polysaccharide biosynthesis protein
V529_RS16735	COG0489	protein tyrosine kinase activity
V529_RS16740	COG3944	biosynthesis protein
V529_RS16745	COG1396	sequence-specific DNA binding
V529_RS16750	COG2272	Belongs to the type-B carboxylesterase lipase family
V529_RS16760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
V529_RS16765	COG2364	Membrane
V529_RS16770	COG0456	acetyltransferase
V529_RS16775	COG3479	Phenolic acid decarboxylase
V529_RS16825	COG2223	nitrite transmembrane transporter activity
V529_RS16830	COG1609	Transcriptional regulator
V529_RS16840	COG0583	DNA-binding transcription factor activity
V529_RS16845	COG2828	Protein conserved in bacteria
V529_RS16850	COG2814	Major facilitator Superfamily
V529_RS16850	COG0477	Major facilitator Superfamily
V529_RS16855	COG1611	Belongs to the LOG family
V529_RS16860	COG1694	Mazg nucleotide pyrophosphohydrolase
V529_RS16865	COG0659	secondary active sulfate transmembrane transporter activity
V529_RS16870	COG0288	reversible hydration of carbon dioxide
V529_RS16875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
V529_RS16880	COG4290	ribonuclease
V529_RS16885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
V529_RS16890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS16900	COG0391	Required for morphogenesis under gluconeogenic growth conditions
V529_RS16910	COG1051	belongs to the nudix hydrolase family
V529_RS16915	COG0492	ferredoxin-NADP+ reductase activity
V529_RS16920	COG0791	NLP P60 protein
V529_RS16920	COG3883	PFAM NLP P60 protein
V529_RS16925	COG0457	Tetratricopeptide repeat
V529_RS16930	COG5002	protein histidine kinase activity
V529_RS16935	COG0745	RESPONSE REGULATOR receiver
V529_RS16940	COG1132	(ABC) transporter
V529_RS16945	COG0140	phosphoribosyl-ATP diphosphatase activity
V529_RS16945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
V529_RS16970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
V529_RS16985	COG4990	cell redox homeostasis
V529_RS16990	COG0110	maltose O-acetyltransferase activity
V529_RS17010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
V529_RS17020	COG2188	Transcriptional regulator
V529_RS17025	COG1309	transcriptional regulator
V529_RS17030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
V529_RS17035	COG1950	PFAM Membrane protein of
V529_RS17040	COG1983	PspC domain protein
V529_RS17045	COG3595	metallopeptidase activity
V529_RS17060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
V529_RS17070	COG4897	Protein conserved in bacteria
V529_RS17075	COG0574	Belongs to the PEP-utilizing enzyme family
V529_RS17075	COG3848	Pyruvate phosphate dikinase
V529_RS17080	COG1309	transcriptional regulator
V529_RS17085	COG2814	Major facilitator Superfamily
V529_RS17090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V529_RS17100	COG0793	Belongs to the peptidase S41A family
V529_RS17100	COG3409	Peptidoglycan-binding domain 1 protein
V529_RS17105	COG3420	alginic acid biosynthetic process
V529_RS17110	COG2177	Part of the ABC transporter FtsEX involved in
V529_RS17115	COG2884	Cell division ATP-binding protein ftsE
V529_RS17120	COG2010	Cytochrome c
V529_RS17125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS17130	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
V529_RS17140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
V529_RS17155	COG1516	flagellar protein fliS
V529_RS17160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
V529_RS17165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
V529_RS17185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
V529_RS17190	COG4786	Flagellar basal body rod
V529_RS17190	COG1256	bacterial-type flagellum assembly
V529_RS17195	COG3418	PFAM FlgN family protein
V529_RS17200	COG2747	anti-sigma28 factor FlgM
V529_RS17210	COG1040	competence protein
V529_RS17220	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
V529_RS17225	COG1307	EDD domain protein, DegV family
V529_RS17230	COG2197	response regulator
V529_RS17235	COG4585	Histidine kinase
V529_RS17240	COG1739	Uncharacterized protein family UPF0029
V529_RS17245	COG1316	TRANSCRIPTIONal
V529_RS17250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
V529_RS17255	COG0438	transferase activity, transferring glycosyl groups
V529_RS17260	COG1215	transferase activity, transferring glycosyl groups
V529_RS17265	COG3206	protein involved in exopolysaccharide biosynthesis
V529_RS17270	COG3307	-O-antigen
V529_RS17275	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
V529_RS17280	COG0297	glycogen (starch) synthase activity
V529_RS17280	COG0438	transferase activity, transferring glycosyl groups
V529_RS17285	COG2244	polysaccharide biosynthetic process
V529_RS17295	COG2247	cell wall binding repeat
V529_RS17295	COG0860	N-Acetylmuramoyl-L-alanine amidase
V529_RS17300	COG2385	sporulation resulting in formation of a cellular spore
V529_RS17300	COG2247	cell wall binding repeat
V529_RS17310	COG1316	TRANSCRIPTIONal
V529_RS17315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
V529_RS17320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
V529_RS17325	COG1134	teichoic acid transport
V529_RS17330	COG1682	transport, permease protein
V529_RS17335	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V529_RS17345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
V529_RS17350	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
V529_RS17355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V529_RS17360	COG4193	domain, Protein
V529_RS17365	COG1482	cell wall glycoprotein biosynthetic process
V529_RS17370	COG0697	spore germination
V529_RS17375	COG0814	amino acid
V529_RS17385	COG1215	transferase activity, transferring glycosyl groups
V529_RS17390	COG2814	Major facilitator Superfamily
V529_RS17395	COG1316	TRANSCRIPTIONal
V529_RS17400	COG0561	phosphatase activity
V529_RS17405	COG2433	Pfam Transposase IS66
V529_RS17410	COG0791	NLP P60 protein
V529_RS17415	COG2843	Capsule synthesis protein
V529_RS17425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
V529_RS17430	COG0697	spore germination
V529_RS17435	COG0814	amino acid
V529_RS17445	COG1609	Transcriptional regulator
V529_RS17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
V529_RS17460	COG1129	ABC transporter
V529_RS17465	COG1172	Belongs to the binding-protein-dependent transport system permease family
V529_RS17470	COG1879	ABC-type sugar transport system periplasmic component
V529_RS17475	COG3103	Sh3 type 3 domain protein
V529_RS17480	COG2249	NAD(P)H dehydrogenase (quinone) activity
V529_RS17485	COG3527	Alpha-acetolactate decarboxylase
V529_RS17490	COG0028	Belongs to the TPP enzyme family
V529_RS17495	COG0583	DNA-binding transcription factor activity
V529_RS17500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
V529_RS17515	COG5337	Spore coat protein CotH
V529_RS17525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
V529_RS17535	COG0405	Gamma-glutamyltransferase
V529_RS17540	COG1522	sequence-specific DNA binding
V529_RS17545	COG2059	Chromate
V529_RS17550	COG2059	Chromate
V529_RS17560	COG0655	NAD(P)H dehydrogenase (quinone) activity
V529_RS17565	COG0583	DNA-binding transcription factor activity
V529_RS17585	COG5444	nuclease activity
V529_RS17600	COG3878	Protein conserved in bacteria
V529_RS17605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
V529_RS17610	COG4464	protein tyrosine phosphatase activity
V529_RS17615	COG0489	protein tyrosine kinase activity
V529_RS17620	COG3944	biosynthesis protein
V529_RS17630	COG4715	Zinc finger, swim domain protein
V529_RS17635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
V529_RS17640	COG0561	phosphatase activity
V529_RS17645	COG1349	DNA-binding transcription factor activity
V529_RS17650	COG0629	single-stranded DNA binding
V529_RS17675	COG0457	Tetratricopeptide repeat
V529_RS17680	COG4786	Flagellar basal body rod
V529_RS17685	COG4786	Flagellar basal body rod
V529_RS17690	COG1077	Cell shape determining protein MreB Mrl
V529_RS17695	COG1609	Transcriptional regulator
V529_RS17700	COG1846	Transcriptional regulator
V529_RS17705	COG2814	Major facilitator Superfamily
V529_RS17710	COG1953	Uracil, thiamine, allantoin
V529_RS17715	COG0477	Major facilitator Superfamily
V529_RS17720	COG1335	isochorismatase
V529_RS17725	COG0004	ammonium transporteR
V529_RS17730	COG0347	Belongs to the P(II) protein family
V529_RS17735	COG0772	Belongs to the SEDS family
V529_RS17740	COG0671	phosphoesterase, PA-phosphatase related
V529_RS17750	COG0739	heme binding
V529_RS17755	COG1247	-acetyltransferase
V529_RS17770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V529_RS17785	COG0726	polysaccharide deacetylase
V529_RS17790	COG1959	2 iron, 2 sulfur cluster binding
V529_RS17805	COG0831	urea catabolic process
V529_RS17815	COG1994	Peptidase M50
V529_RS17820	COG0457	Tetratricopeptide repeat
V529_RS17830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
V529_RS17835	COG2304	oxidoreductase activity
V529_RS17840	COG2304	oxidoreductase activity
V529_RS17845	COG2385	sporulation resulting in formation of a cellular spore
V529_RS17850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
V529_RS17860	COG4836	Membrane
V529_RS17930	COG0698	ribose 5-phosphate isomerase
V529_RS17935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
V529_RS17945	COG0009	L-threonylcarbamoyladenylate synthase
V529_RS17950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
V529_RS17970	COG2890	protein-(glutamine-N5) methyltransferase activity
V529_RS17975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
V529_RS17980	COG0346	lactoylglutathione lyase activity
V529_RS17985	COG0789	Transcriptional regulator
V529_RS17990	COG0679	Auxin Efflux Carrier
V529_RS17995	COG0281	malic enzyme
V529_RS18010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
V529_RS18015	COG1494	fructose-1,6-bisphosphatase
V529_RS18020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
V529_RS18030	COG0191	fructose-bisphosphate aldolase activity
V529_RS18035	COG2204	response regulator
V529_RS18040	COG4821	SIS domain
V529_RS18055	COG0247	lactate metabolic process
V529_RS18055	COG2181	nitrate reductase activity
V529_RS18060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V529_RS18075	COG1132	(ABC) transporter
V529_RS18080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
V529_RS18090	COG2181	nitrate reductase activity
V529_RS18095	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
V529_RS18100	COG1140	nitrate reductase beta subunit
V529_RS18105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
V529_RS18110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V529_RS18120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
V529_RS18125	COG2223	nitrite transmembrane transporter activity
V529_RS18135	COG4506	Protein conserved in bacteria
V529_RS18145	COG3391	amine dehydrogenase activity
V529_RS18150	COG3391	amine dehydrogenase activity
V529_RS18155	COG0457	Tetratricopeptide repeat
V529_RS18200	COG0010	Belongs to the arginase family
V529_RS18205	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
V529_RS18210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
V529_RS18225	COG1994	Peptidase M50
V529_RS18230	COG1942	4-Oxalocrotonate Tautomerase
V529_RS18235	COG1846	Transcriptional regulator
V529_RS18240	COG0531	amino acid
V529_RS18245	COG3465	dGTPase activity
V529_RS18250	COG1078	dGTPase activity
V529_RS18265	COG1695	Transcriptional regulator
V529_RS18275	COG1131	(ABC) transporter
V529_RS18280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
V529_RS18310	COG0583	DNA-binding transcription factor activity
V529_RS18315	COG2855	membrane
V529_RS18320	COG0280	phosphate acetyltransferase
V529_RS18330	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS18335	COG0436	Aminotransferase
V529_RS18365	COG2814	Major facilitator Superfamily
V529_RS18370	COG2814	Major facilitator Superfamily
V529_RS18375	COG0833	amino acid
V529_RS18380	COG4187	Peptidase family M20/M25/M40
V529_RS18385	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS18390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
V529_RS18395	COG2205	protein histidine kinase activity
V529_RS18400	COG0745	RESPONSE REGULATOR receiver
V529_RS18415	COG1131	(ABC) transporter
V529_RS18420	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
V529_RS18425	COG1091	dTDP-4-dehydrorhamnose reductase activity
V529_RS18430	COG1088	dTDP-glucose 4,6-dehydratase activity
V529_RS18435	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
V529_RS18440	COG3980	spore coat polysaccharide biosynthesis protein
V529_RS18445	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
V529_RS18450	COG2089	acid synthase
V529_RS18455	COG0456	acetyltransferase
V529_RS18460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
V529_RS18465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
V529_RS18470	COG0463	Glycosyl transferase, family 2
V529_RS18480	COG2363	Small membrane protein
V529_RS18485	COG2233	PERMEase
V529_RS18500	COG1216	Glycosyl transferase, family 2
V529_RS18515	COG1695	Transcriptional regulator
V529_RS18520	COG0351	phosphomethylpyrimidine kinase
V529_RS18530	COG1621	beta-fructofuranosidase activity
V529_RS18535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
V529_RS18535	COG1263	PTS System
V529_RS18540	COG3711	transcriptional antiterminator
V529_RS18550	COG1404	Belongs to the peptidase S8 family
V529_RS18555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
V529_RS18560	COG0778	Nitroreductase
V529_RS18565	COG0772	Belongs to the SEDS family
V529_RS18570	COG0454	-acetyltransferase
V529_RS18590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
V529_RS18595	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
V529_RS18600	COG2261	transglycosylase associated protein
V529_RS18605	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
V529_RS18610	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
V529_RS18615	COG2246	polysaccharide biosynthetic process
V529_RS18620	COG1309	transcriptional regulator
V529_RS18640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
V529_RS18645	COG2837	iron assimilation
V529_RS18650	COG2822	iron ion transport
V529_RS18665	COG0583	DNA-binding transcription factor activity
V529_RS18675	COG1346	cytolysis
V529_RS18680	COG4895	conserved protein (DUF2196)
V529_RS18685	COG0789	Transcriptional regulator
V529_RS18690	COG5504	Zn-dependent protease
V529_RS18695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
V529_RS18700	COG0346	lactoylglutathione lyase activity
V529_RS18705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS18710	COG1404	Belongs to the peptidase S8 family
V529_RS18715	COG1442	glycosyl transferase family 8
V529_RS18720	COG1846	Transcriptional regulator
V529_RS18725	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
V529_RS18730	COG2357	RelA SpoT domain protein
V529_RS18735	COG1575	Belongs to the MenA family. Type 1 subfamily
V529_RS18750	COG1696	Membrane protein involved in D-alanine export
V529_RS18760	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
V529_RS18765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
V529_RS18770	COG1486	melibiose metabolic process
V529_RS18775	COG1447	Phosphotransferase system cellobiose-specific component IIA
V529_RS18780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS18785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS18790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
V529_RS18790	COG3711	transcriptional antiterminator
V529_RS18800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
V529_RS18815	COG0640	Transcriptional regulator
V529_RS18820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
V529_RS18825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS18830	COG1447	Phosphotransferase system cellobiose-specific component IIA
V529_RS18835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
V529_RS18840	COG2723	6-phospho-beta-galactosidase activity
V529_RS18845	COG1940	carbohydrate kinase activity
V529_RS18850	COG1482	cell wall glycoprotein biosynthetic process
V529_RS18860	COG0753	catalase activity
V529_RS18865	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
V529_RS18870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
V529_RS18875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
V529_RS18880	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
V529_RS18885	COG4988	ABC transporter
V529_RS18890	COG1294	oxidase, subunit
V529_RS18895	COG1271	oxidase subunit
V529_RS18900	COG3493	citrate carrier protein
V529_RS18905	COG0726	polysaccharide deacetylase
V529_RS18910	COG3842	ATPase activity
V529_RS18915	COG2508	Transcriptional regulator
V529_RS18920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS18930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
V529_RS18940	COG4894	glucomannan catabolic process
V529_RS18945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
V529_RS18950	COG0500	methyltransferase
V529_RS18955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V529_RS18975	COG0753	catalase activity
V529_RS18975	COG0693	protein deglycase activity
V529_RS18980	COG2851	Citrate transporter
V529_RS18985	COG2273	Hydrolase Family 16
V529_RS18990	COG3711	transcriptional antiterminator
V529_RS18995	COG2270	Major facilitator Superfamily
V529_RS19000	COG0513	Belongs to the DEAD box helicase family
V529_RS19035	COG3209	COG3209 Rhs family protein
V529_RS19045	COG0697	spore germination
V529_RS19050	COG0589	response to stress
V529_RS19060	COG0494	nUDIX hydrolase
V529_RS19065	COG3507	Belongs to the glycosyl hydrolase 43 family
V529_RS19090	COG0010	Belongs to the arginase family
V529_RS19095	COG0833	amino acid
V529_RS19100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
V529_RS19105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
V529_RS19115	COG2390	Transcriptional regulator
V529_RS19120	COG0561	phosphatase activity
V529_RS19150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
V529_RS19155	COG5294	Protein conserved in bacteria
V529_RS19160	COG0577	efflux transmembrane transporter activity
V529_RS19165	COG1136	(ABC) transporter
V529_RS19170	COG2205	protein histidine kinase activity
V529_RS19175	COG0745	RESPONSE REGULATOR receiver
V529_RS19190	COG1082	Xylose isomerase domain protein TIM barrel
V529_RS19200	COG2814	Major facilitator Superfamily
V529_RS19230	COG1349	DNA-binding transcription factor activity
V529_RS19235	COG0667	Aldo Keto reductase
V529_RS19240	COG2814	Major facilitator Superfamily
V529_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS19260	COG2197	response regulator
V529_RS19265	COG4585	Histidine kinase
V529_RS19270	COG3239	Fatty acid desaturase
V529_RS19280	COG1309	transcriptional regulator
V529_RS19285	COG1012	belongs to the aldehyde dehydrogenase family
V529_RS19290	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
V529_RS19300	COG0640	Transcriptional regulator
V529_RS19305	COG2814	Major facilitator Superfamily
V529_RS19310	COG1714	RDD family
V529_RS19320	COG0450	alkyl hydroperoxide reductase
V529_RS19325	COG3634	alkyl hydroperoxide reductase activity
V529_RS19330	COG3177	Filamentation induced by cAMP protein fic
V529_RS19335	COG1113	amino acid transport
V529_RS19345	COG2080	2 iron, 2 sulfur cluster binding
V529_RS19360	COG2068	MobA-Related Protein
V529_RS19365	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
V529_RS19400	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
V529_RS19405	COG0667	Aldo Keto reductase
V529_RS19410	COG0456	acetyltransferase
V529_RS19415	COG0457	Tetratricopeptide repeat
V529_RS19420	COG0010	Belongs to the arginase family
V529_RS19425	COG0833	amino acid
V529_RS19430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
V529_RS19435	COG5658	integral membrane protein
V529_RS19440	COG0640	Transcriptional regulator
V529_RS19445	COG3829	transcription factor binding
V529_RS19455	COG0488	(ABC) transporter
V529_RS19470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
V529_RS19475	COG5002	protein histidine kinase activity
V529_RS19480	COG0745	RESPONSE REGULATOR receiver
V529_RS19485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
V529_RS19490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
V529_RS19495	COG4853	Protein conserved in bacteria
V529_RS19500	COG4863	YycH protein
V529_RS19505	COG5002	protein histidine kinase activity
V529_RS19510	COG0745	RESPONSE REGULATOR receiver
V529_RS19545	COG0346	lactoylglutathione lyase activity
V529_RS19550	COG0305	Participates in initiation and elongation during chromosome replication
V529_RS19565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
V529_RS19580	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
V529_RS19585	COG0438	transferase activity, transferring glycosyl groups
V529_RS19605	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
V529_RS19610	COG4241	membrane
V529_RS19620	COG5577	PFAM Coat F domain
V529_RS19625	COG1733	regulation of RNA biosynthetic process
V529_RS19635	COG0697	spore germination
V529_RS19640	COG1621	beta-fructofuranosidase activity
V529_RS19645	COG1621	beta-fructofuranosidase activity
V529_RS19655	COG2318	DinB family
V529_RS19660	COG2211	Major facilitator Superfamily
V529_RS19675	COG0778	Nitroreductase
V529_RS19680	COG1846	Transcriptional regulator
V529_RS19685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
V529_RS19690	COG1846	Transcriptional regulator
V529_RS19695	COG2153	protein acetylation
V529_RS19705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
V529_RS19710	COG0583	DNA-binding transcription factor activity
V529_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS19735	COG1404	Belongs to the peptidase S8 family
V529_RS19740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
V529_RS19745	COG0697	spore germination
V529_RS19760	COG1959	2 iron, 2 sulfur cluster binding
V529_RS19770	COG1331	Highly conserved protein containing a thioredoxin domain
V529_RS19775	COG1266	CAAX protease self-immunity
V529_RS19780	COG0477	Major facilitator Superfamily
V529_RS19780	COG2814	Major facilitator Superfamily
V529_RS19785	COG0346	lactoylglutathione lyase activity
V529_RS19790	COG1609	Transcriptional regulator
V529_RS19795	COG0708	Exodeoxyribonuclease III
V529_RS19800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
V529_RS19805	COG2169	Transcriptional regulator
V529_RS19815	COG0629	single-stranded DNA binding
V529_RS19825	COG0012	GTP binding
V529_RS19830	COG0243	molybdopterin cofactor binding
V529_RS19835	COG4481	Protein conserved in bacteria
V529_RS19840	COG3949	Membrane
V529_RS19855	COG1475	DNA binding
V529_RS19860	COG1192	Involved in chromosome partitioning
V529_RS19885	COG1847	R3H domain protein
V529_RS19890	COG0706	membrane insertase activity
V529_RS19905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS19905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS19905	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS19905	COG3321	synthase
V529_RS19905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS19910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
V529_RS19910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS19910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
V529_RS19910	COG3321	synthase
V529_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
V529_RS19915	COG4221	oxidoreductase activity
V529_RS19915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
V529_RS19915	COG3321	synthase
V529_RS19915	COG0300	oxidoreductase activity
V529_RS19925	COG2337	Toxic component of a toxin-antitoxin (TA) module
V529_RS19935	COG1388	LysM domain