locus-tag	class	description
S100072_RS00010	COG0592	DNA-directed DNA polymerase activity
S100072_RS00015	COG2501	S4 domain
S100072_RS00030	COG0187	DNA topoisomerase II activity
S100072_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S100072_RS00070	COG0516	GMP reductase activity
S100072_RS00070	COG0517	IMP dehydrogenase activity
S100072_RS00075	COG1686	Belongs to the peptidase S11 family
S100072_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
S100072_RS00105	COG1428	Deoxynucleoside kinase
S100072_RS00110	COG1428	Deoxynucleoside kinase
S100072_RS00115	COG3858	chitin binding
S100072_RS00115	COG1388	LysM domain
S100072_RS00120	COG1335	isochorismatase
S100072_RS00125	COG0590	tRNA wobble adenosine to inosine editing
S100072_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S100072_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S100072_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S100072_RS00195	COG3853	Toxic anion resistance protein (TelA)
S100072_RS00200	COG1982	Orn Lys Arg decarboxylase major
S100072_RS00210	COG3870	Protein conserved in bacteria
S100072_RS00215	COG1728	Protein conserved in bacteria
S100072_RS00220	COG0470	DNA polymerase III
S100072_RS00225	COG1774	PSP1 C-terminal conserved region
S100072_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S100072_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S100072_RS00250	COG2002	toxin-antitoxin pair type II binding
S100072_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS00260	COG0084	hydrolase, TatD family'
S100072_RS00265	COG3583	domain protein
S100072_RS00265	COG3584	3D domain protein
S100072_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S100072_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S100072_RS00285	COG4466	Protein conserved in bacteria
S100072_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S100072_RS00305	COG0251	oxidation-reduction process
S100072_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S100072_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S100072_RS00345	COG2002	toxin-antitoxin pair type II binding
S100072_RS00355	COG3956	TIGRFAM MazG family protein
S100072_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S100072_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S100072_RS00380	COG1098	S1 RNA binding domain
S100072_RS00395	COG2208	phosphoserine phosphatase activity
S100072_RS00400	COG2304	oxidoreductase activity
S100072_RS00405	COG0515	serine threonine protein kinase
S100072_RS00410	COG0037	tRNA processing
S100072_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
S100072_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S100072_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S100072_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S100072_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S100072_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
S100072_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S100072_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
S100072_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S100072_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S100072_RS00475	COG1396	sequence-specific DNA binding
S100072_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S100072_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S100072_RS00565	COG4463	regulation of RNA biosynthetic process
S100072_RS00570	COG3880	PFAM UvrB UvrC protein
S100072_RS00580	COG0542	response to heat
S100072_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S100072_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S100072_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
S100072_RS00615	COG1045	serine acetyltransferase
S100072_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S100072_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S100072_RS00635	COG3688	RNA-binding protein containing a PIN domain
S100072_RS00640	COG1595	DNA-templated transcription, initiation
S100072_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S100072_RS00695	COG1358	cellular component organization or biogenesis
S100072_RS00720	COG0596	Alpha beta hydrolase
S100072_RS00830	COG0201	protein transport
S100072_RS00840	COG0024	Methionine aminopeptidase
S100072_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S100072_RS00880	COG1122	ATPase activity
S100072_RS00885	COG1122	ATPase activity
S100072_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S100072_RS00910	COG2226	methyltransferase
S100072_RS00915	COG2318	DinB family
S100072_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
S100072_RS00930	COG0489	protein tyrosine kinase activity
S100072_RS00940	COG2194	sulfuric ester hydrolase activity
S100072_RS00945	COG0726	polysaccharide deacetylase
S100072_RS01005	COG0738	Major facilitator superfamily
S100072_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S100072_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
S100072_RS01030	COG0385	Bile acid
S100072_RS01035	COG2819	hydrolase of the alpha beta superfamily
S100072_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S100072_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S100072_RS01055	COG2207	Transcriptional regulator
S100072_RS01060	COG3876	Protein conserved in bacteria
S100072_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
S100072_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S100072_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S100072_RS01075	COG1263	PTS System
S100072_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S100072_RS01090	COG1683	Conserved Protein
S100072_RS01120	COG1595	DNA-templated transcription, initiation
S100072_RS01125	COG5662	AntiSigma factor
S100072_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S100072_RS01135	COG4856	YbbR-like protein
S100072_RS01175	COG1346	cytolysis
S100072_RS01180	COG1380	Effector of murein hydrolase LrgA
S100072_RS01185	COG1846	Transcriptional regulator
S100072_RS01190	COG1113	amino acid transport
S100072_RS01195	COG1011	Hydrolase
S100072_RS01205	COG2197	response regulator
S100072_RS01210	COG1131	(ABC) transporter
S100072_RS01250	COG0531	amino acid
S100072_RS01275	COG0584	glycerophosphoryl diester phosphodiesterase
S100072_RS01280	COG2271	Major facilitator Superfamily
S100072_RS01295	COG2368	4-hydroxyphenylacetate
S100072_RS01305	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS01320	COG0371	Dehydrogenase
S100072_RS01330	COG1183	phosphatidylcholine synthase activity
S100072_RS01335	COG0586	Pfam SNARE associated Golgi protein
S100072_RS01340	COG0688	phosphatidylethanolamine metabolic process
S100072_RS01355	COG1301	dicarboxylic acid transport
S100072_RS01365	COG0833	amino acid
S100072_RS01370	COG2040	homocysteine
S100072_RS01375	COG1115	amino acid carrier protein
S100072_RS01380	COG2066	Belongs to the glutaminase family
S100072_RS01390	COG0784	Response regulator, receiver
S100072_RS01395	COG3173	Aminoglycoside phosphotransferase
S100072_RS01415	COG3773	Cell wall hydrolase
S100072_RS01425	COG3540	Alkaline phosphatase
S100072_RS01430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S100072_RS01435	COG0805	protein transport
S100072_RS01445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S100072_RS01450	COG0477	Major facilitator Superfamily
S100072_RS01455	COG1309	transcriptional regulator
S100072_RS01460	COG0252	asparaginase activity
S100072_RS01465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S100072_RS01470	COG1405	negative regulation of cell septum assembly
S100072_RS01470	COG3012	SEC-C Motif Domain Protein
S100072_RS01475	COG0667	Aldo Keto reductase
S100072_RS01485	COG1595	DNA-templated transcription, initiation
S100072_RS01490	COG1595	DNA-templated transcription, initiation
S100072_RS01495	COG1876	peptidase activity
S100072_RS01500	COG0457	Tetratricopeptide repeat
S100072_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS01520	COG0366	Alpha amylase catalytic
S100072_RS01525	COG0803	Belongs to the bacterial solute-binding protein 9 family
S100072_RS01530	COG1121	(ABC) transporter
S100072_RS01535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S100072_RS01540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S100072_RS01545	COG2310	stress, protein
S100072_RS01550	COG2310	stress, protein
S100072_RS01555	COG2310	stress, protein
S100072_RS01560	COG0861	Integral membrane protein TerC family
S100072_RS01570	COG3853	Toxic anion resistance protein (TelA)
S100072_RS01575	COG0477	Major facilitator Superfamily
S100072_RS01580	COG4175	Glycine betaine
S100072_RS01580	COG0517	IMP dehydrogenase activity
S100072_RS01585	COG4176	ABC-type proline glycine betaine transport system permease component
S100072_RS01590	COG2113	Glycine betaine
S100072_RS01595	COG1473	amidohydrolase
S100072_RS01620	COG2814	Major facilitator Superfamily
S100072_RS01625	COG1846	Transcriptional regulator
S100072_RS01630	COG1280	lysine exporter protein (LysE YggA)
S100072_RS01640	COG1113	amino acid transport
S100072_RS01645	COG3665	Urea carboxylase-associated protein
S100072_RS01660	COG1660	Displays ATPase and GTPase activities
S100072_RS01670	COG2271	Major facilitator Superfamily
S100072_RS01680	COG3458	cephalosporin-C deacetylase activity
S100072_RS01685	COG3541	Predicted nucleotidyltransferase
S100072_RS01690	COG0506	proline dehydrogenase activity
S100072_RS01695	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS01705	COG2508	Transcriptional regulator
S100072_RS01715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S100072_RS01715	COG1587	Uroporphyrinogen-III synthase
S100072_RS01720	COG2146	nitrite reductase [NAD(P)H] activity
S100072_RS01725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S100072_RS01730	COG0243	molybdopterin cofactor binding
S100072_RS01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S100072_RS01745	COG0523	cobalamin synthesis protein
S100072_RS01750	COG1063	alcohol dehydrogenase
S100072_RS01755	COG1714	RDD family
S100072_RS01765	COG2723	6-phospho-beta-galactosidase activity
S100072_RS01775	COG3209	COG3209 Rhs family protein
S100072_RS01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S100072_RS01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S100072_RS01790	COG1733	regulation of RNA biosynthetic process
S100072_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS01815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S100072_RS01830	COG2364	Membrane
S100072_RS01835	COG1126	abc transporter atp-binding protein
S100072_RS01840	COG0765	amino acid transport
S100072_RS01845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S100072_RS01850	COG0583	DNA-binding transcription factor activity
S100072_RS01855	COG0163	prenyltransferase activity
S100072_RS01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S100072_RS01875	COG3104	oligopeptide transport
S100072_RS01880	COG5434	Belongs to the glycosyl hydrolase 28 family
S100072_RS01890	COG0697	spore germination
S100072_RS01900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S100072_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S100072_RS01910	COG0456	acetyltransferase
S100072_RS01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S100072_RS01920	COG0765	amino acid transport
S100072_RS01925	COG1126	abc transporter atp-binding protein
S100072_RS01930	COG1473	amidohydrolase
S100072_RS01935	COG2079	MmgE PrpD family protein
S100072_RS01940	COG1136	(ABC) transporter
S100072_RS01945	COG0577	efflux transmembrane transporter activity
S100072_RS01955	COG3850	Histidine kinase
S100072_RS01955	COG5002	protein histidine kinase activity
S100072_RS01960	COG0457	Tetratricopeptide repeat
S100072_RS01975	COG0527	aspartate kinase activity
S100072_RS01980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS01985	COG4605	iron ion homeostasis
S100072_RS01990	COG4604	ABC transporter, ATP-binding protein
S100072_RS01995	COG4607	ABC-type enterochelin transport system periplasmic component
S100072_RS02000	COG2814	Major facilitator Superfamily
S100072_RS02005	COG1309	transcriptional regulator
S100072_RS02010	COG0778	Nitroreductase
S100072_RS02015	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S100072_RS02020	COG0640	Transcriptional regulator
S100072_RS02025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S100072_RS02030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S100072_RS02035	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS02050	COG4549	nuclear export factor GLE1
S100072_RS02055	COG1276	copper resistance
S100072_RS02055	COG2372	response to copper ion
S100072_RS02060	COG1349	DNA-binding transcription factor activity
S100072_RS02070	COG2213	PTS system mannitol-specific
S100072_RS02075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S100072_RS02095	COG0561	phosphatase activity
S100072_RS02105	COG1914	H( )-stimulated, divalent metal cation uptake system
S100072_RS02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S100072_RS02125	COG1414	Transcriptional regulator
S100072_RS02130	COG2755	lipolytic protein G-D-S-L family
S100072_RS02140	COG2329	Antibiotic biosynthesis monooxygenase
S100072_RS02145	COG0768	penicillin binding
S100072_RS02150	COG4989	oxidoreductase activity
S100072_RS02155	COG3711	transcriptional antiterminator
S100072_RS02160	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS02165	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS02170	COG1917	Cupin 2, conserved barrel domain protein
S100072_RS02175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S100072_RS02180	COG3871	stress protein (general stress protein 26)
S100072_RS02190	COG2814	Major facilitator Superfamily
S100072_RS02195	COG1522	sequence-specific DNA binding
S100072_RS02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S100072_RS02200	COG0551	DNA topoisomerase type I activity
S100072_RS02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S100072_RS02230	COG0531	amino acid
S100072_RS02235	COG0494	nUDIX hydrolase
S100072_RS02240	COG0028	Belongs to the TPP enzyme family
S100072_RS02245	COG1388	LysM domain
S100072_RS02245	COG5632	N-Acetylmuramoyl-L-alanine amidase
S100072_RS02245	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS02265	COG0457	Tetratricopeptide repeat
S100072_RS02295	COG1914	H( )-stimulated, divalent metal cation uptake system
S100072_RS02310	COG4876	unkown
S100072_RS02320	COG2076	Multidrug Resistance protein
S100072_RS02325	COG2217	Heavy metal translocating P-type atpase
S100072_RS02330	COG3729	General stress protein
S100072_RS02335	COG0662	Cupin 2, conserved barrel domain protein
S100072_RS02340	COG2329	Antibiotic biosynthesis monooxygenase
S100072_RS02345	COG3546	catalase activity
S100072_RS02350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S100072_RS02360	COG4565	transcriptional regulatory protein
S100072_RS02365	COG1301	dicarboxylic acid transport
S100072_RS02370	COG0628	permease
S100072_RS02375	COG1131	(ABC) transporter
S100072_RS02380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S100072_RS02390	COG1960	acyl-CoA dehydrogenase activity
S100072_RS02405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S100072_RS02410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS02420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S100072_RS02425	COG0513	Belongs to the DEAD box helicase family
S100072_RS02430	COG3402	PFAM membrane-flanked domain
S100072_RS02435	COG3428	Bacterial PH domain
S100072_RS02440	COG0705	Rhomboid family
S100072_RS02450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S100072_RS02455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S100072_RS02460	COG0864	Transcriptional regulator
S100072_RS02465	COG2337	Toxic component of a toxin-antitoxin (TA) module
S100072_RS02470	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS02475	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS02480	COG2172	sigma factor antagonist activity
S100072_RS02485	COG2208	phosphoserine phosphatase activity
S100072_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS02500	COG1191	sigma factor activity
S100072_RS02505	COG2208	phosphoserine phosphatase activity
S100072_RS02510	COG2183	response to ionizing radiation
S100072_RS02560	COG2249	NAD(P)H dehydrogenase (quinone) activity
S100072_RS02570	COG0477	Major facilitator Superfamily
S100072_RS02590	COG2030	dehydratase
S100072_RS02605	COG1959	2 iron, 2 sulfur cluster binding
S100072_RS02610	COG2910	NAD(P)H-binding
S100072_RS02620	COG1309	transcriptional regulator
S100072_RS02635	COG1278	Cold shock
S100072_RS02640	COG1329	Transcriptional regulator
S100072_RS02645	COG1794	racemase activity, acting on amino acids and derivatives
S100072_RS02660	COG3621	Patatin-like phospholipase
S100072_RS02670	COG0662	Cupin 2, conserved barrel domain protein
S100072_RS02710	COG0662	Cupin 2, conserved barrel domain protein
S100072_RS02715	COG2318	DinB family
S100072_RS02720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S100072_RS02745	COG1064	alcohol dehydrogenase
S100072_RS02750	COG0789	Transcriptional regulator
S100072_RS02760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S100072_RS02780	COG1309	transcriptional regulator
S100072_RS02785	COG5577	PFAM Coat F domain
S100072_RS02795	COG1063	alcohol dehydrogenase
S100072_RS02800	COG5577	PFAM Coat F domain
S100072_RS02810	COG4585	Histidine kinase
S100072_RS02815	COG2197	response regulator
S100072_RS02820	COG2409	Drug exporters of the RND superfamily
S100072_RS02830	COG0488	(ABC) transporter
S100072_RS02835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S100072_RS02840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS02850	COG2814	Major facilitator Superfamily
S100072_RS02855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S100072_RS02870	COG0456	acetyltransferase
S100072_RS02875	COG0789	Transcriptional regulator
S100072_RS02875	COG4978	Transcriptional regulator
S100072_RS02880	COG0697	spore germination
S100072_RS02885	COG1051	belongs to the nudix hydrolase family
S100072_RS02890	COG2226	methyltransferase
S100072_RS02910	COG1802	Transcriptional regulator
S100072_RS02915	COG1819	glycosyl
S100072_RS02930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S100072_RS02935	COG1388	LysM domain
S100072_RS02940	COG2814	Major facilitator Superfamily
S100072_RS02945	COG2188	Transcriptional regulator
S100072_RS02950	COG2186	Transcriptional regulator
S100072_RS02955	COG2807	transmembrane transport
S100072_RS02960	COG2076	Multidrug Resistance protein
S100072_RS02965	COG2076	Multidrug Resistance protein
S100072_RS02970	COG1309	transcriptional regulator
S100072_RS02975	COG0531	amino acid
S100072_RS02985	COG3832	glyoxalase III activity
S100072_RS02990	COG0604	alcohol dehydrogenase
S100072_RS02995	COG2814	Major facilitator Superfamily
S100072_RS03035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S100072_RS03040	COG0802	atpase or kinase
S100072_RS03045	COG1214	PFAM Peptidase M22, glycoprotease
S100072_RS03050	COG0456	acetyltransferase
S100072_RS03055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S100072_RS03060	COG0488	(ABC) transporter
S100072_RS03075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S100072_RS03080	COG0805	protein transport
S100072_RS03115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS03150	COG2814	Major facilitator Superfamily
S100072_RS03155	COG0457	Tetratricopeptide repeat
S100072_RS03160	COG1063	alcohol dehydrogenase
S100072_RS03165	COG2211	Major facilitator Superfamily
S100072_RS03170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S100072_RS03180	COG1842	Phage shock protein A
S100072_RS03185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S100072_RS03190	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S100072_RS03195	COG4260	virion core protein, lumpy skin disease virus
S100072_RS03200	COG2755	lipolytic protein G-D-S-L family
S100072_RS03200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S100072_RS03210	COG1595	DNA-templated transcription, initiation
S100072_RS03215	COG1063	alcohol dehydrogenase
S100072_RS03220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S100072_RS03225	COG0823	Involved in the tonB-independent uptake of proteins
S100072_RS03250	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
S100072_RS03255	COG1305	Transglutaminase-like
S100072_RS03280	COG2252	PERMEase
S100072_RS03285	COG3064	Membrane
S100072_RS03305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S100072_RS03310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
S100072_RS03315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S100072_RS03320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S100072_RS03325	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S100072_RS03340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S100072_RS03355	COG0138	bifunctional purine biosynthesis protein purh
S100072_RS03360	COG0151	Belongs to the GarS family
S100072_RS03370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S100072_RS03380	COG4496	protein, YerC YecD
S100072_RS03385	COG0069	glutamate synthase activity
S100072_RS03400	COG0210	DNA helicase
S100072_RS03410	COG4851	CamS sex pheromone cAM373 precursor
S100072_RS03415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S100072_RS03420	COG1285	pathogenesis
S100072_RS03425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S100072_RS03445	COG1309	transcriptional regulator
S100072_RS03450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S100072_RS03455	COG1597	lipid kinase activity
S100072_RS03460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S100072_RS03465	COG1136	(ABC) transporter
S100072_RS03475	COG1131	(ABC) transporter
S100072_RS03515	COG5444	nuclease activity
S100072_RS03540	COG3546	catalase activity
S100072_RS03545	COG0454	-acetyltransferase
S100072_RS03560	COG2329	Antibiotic biosynthesis monooxygenase
S100072_RS03565	COG0346	lactoylglutathione lyase activity
S100072_RS03575	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS03580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
S100072_RS03590	COG4208	sulfate ABC transporter
S100072_RS03600	COG5583	Uncharacterized small protein (DUF2292)
S100072_RS03605	COG0196	riboflavin kinase activity
S100072_RS03615	COG1846	Transcriptional regulator
S100072_RS03620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S100072_RS03645	COG1131	(ABC) transporter
S100072_RS03660	COG1368	sulfuric ester hydrolase activity
S100072_RS03665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S100072_RS03670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S100072_RS03675	COG1442	glycosyl transferase family 8
S100072_RS03685	COG1442	glycosyl transferase family 8
S100072_RS03690	COG2223	nitrite transmembrane transporter activity
S100072_RS03695	COG0531	amino acid
S100072_RS03700	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS03705	COG0840	transmembrane signaling receptor activity
S100072_RS03720	COG0488	(ABC) transporter
S100072_RS03725	COG0789	Transcriptional regulator
S100072_RS03730	COG2814	Major facilitator Superfamily
S100072_RS03735	COG0488	(ABC) transporter
S100072_RS03740	COG0513	Belongs to the DEAD box helicase family
S100072_RS03750	COG2130	NADP-dependent
S100072_RS03765	COG3866	Pectate lyase
S100072_RS03770	COG0471	metal ion transport
S100072_RS03785	COG3290	protein histidine kinase activity
S100072_RS03790	COG4565	transcriptional regulatory protein
S100072_RS03795	COG3181	Tripartite tricarboxylate transporter family receptor
S100072_RS03805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S100072_RS03810	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S100072_RS03820	COG2258	MOSC domain
S100072_RS03840	COG0024	Methionine aminopeptidase
S100072_RS03845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S100072_RS03845	COG1263	PTS System
S100072_RS03855	COG1368	sulfuric ester hydrolase activity
S100072_RS03865	COG0071	Belongs to the small heat shock protein (HSP20) family
S100072_RS03885	COG0366	Alpha amylase catalytic
S100072_RS03890	COG2188	Transcriptional regulator
S100072_RS03895	COG0778	Nitroreductase
S100072_RS03910	COG0737	Belongs to the 5'-nucleotidase family
S100072_RS03915	COG0693	protein deglycase activity
S100072_RS03920	COG1609	Transcriptional regulator
S100072_RS03935	COG2814	Major facilitator Superfamily
S100072_RS03945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S100072_RS03950	COG4980	gas vesicle protein
S100072_RS03955	COG1295	ribonuclease BN
S100072_RS03960	COG0477	Major facilitator Superfamily
S100072_RS03965	COG0387	Pfam Sodium calcium exchanger
S100072_RS03975	COG0668	transmembrane transport
S100072_RS03980	COG0535	radical SAM domain protein
S100072_RS03990	COG0726	polysaccharide deacetylase
S100072_RS03995	COG2084	Dehydrogenase
S100072_RS04005	COG0598	Magnesium transport protein CorA
S100072_RS04015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S100072_RS04030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S100072_RS04035	COG4637	Psort location Cytoplasmic, score
S100072_RS04040	COG0022	dehydrogenase e1 component
S100072_RS04045	COG0508	dehydrogenase complex catalyzes the overall conversion of
S100072_RS04065	COG1486	melibiose metabolic process
S100072_RS04070	COG1737	Transcriptional regulator
S100072_RS04080	COG1132	(ABC) transporter
S100072_RS04085	COG1132	(ABC) transporter
S100072_RS04090	COG2259	Doxx family
S100072_RS04095	COG2514	catechol 2,3-dioxygenase activity
S100072_RS04105	COG1695	Transcriptional regulator
S100072_RS04110	COG2249	NAD(P)H dehydrogenase (quinone) activity
S100072_RS04115	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S100072_RS04120	COG3848	Pyruvate phosphate dikinase
S100072_RS04120	COG0574	Belongs to the PEP-utilizing enzyme family
S100072_RS04125	COG2732	(Barnase) inhibitor
S100072_RS04130	COG2318	DinB family
S100072_RS04135	COG2814	Major facilitator Superfamily
S100072_RS04140	COG1846	Transcriptional regulator
S100072_RS04145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S100072_RS04145	COG0392	lysyltransferase activity
S100072_RS04150	COG0384	phenazine biosynthesis protein PhzF
S100072_RS04155	COG0778	Nitroreductase
S100072_RS04170	COG1090	epimerase
S100072_RS04185	COG2814	Major facilitator Superfamily
S100072_RS04195	COG3591	Belongs to the peptidase S1B family
S100072_RS04210	COG3103	Sh3 type 3 domain protein
S100072_RS04215	COG5658	integral membrane protein
S100072_RS04220	COG0596	Alpha beta hydrolase
S100072_RS04225	COG0463	Glycosyl transferase, family 2
S100072_RS04230	COG4485	Bacterial membrane protein, YfhO
S100072_RS04235	COG1988	membrane-bound metal-dependent
S100072_RS04240	COG1194	a g-specific adenine glycosylase
S100072_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS04270	COG1132	(ABC) transporter
S100072_RS04275	COG4129	membrane
S100072_RS04285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S100072_RS04290	COG0735	belongs to the Fur family
S100072_RS04430	COG5577	PFAM Coat F domain
S100072_RS04435	COG3340	Belongs to the peptidase S51 family
S100072_RS04455	COG0747	negative chemotaxis
S100072_RS04460	COG0601	transmembrane transport
S100072_RS04465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S100072_RS04470	COG0444	Belongs to the ABC transporter superfamily
S100072_RS04475	COG4608	Belongs to the ABC transporter superfamily
S100072_RS04480	COG0753	catalase activity
S100072_RS04495	COG1116	anion transmembrane transporter activity
S100072_RS04500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S100072_RS04505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S100072_RS04525	COG1476	TRANSCRIPTIONal
S100072_RS04535	COG3382	B3 4 domain protein
S100072_RS04540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S100072_RS04550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S100072_RS04555	COG0789	Transcriptional regulator
S100072_RS04560	COG1664	Polymer-forming cytoskeletal
S100072_RS04565	COG1664	Polymer-forming cytoskeletal
S100072_RS04570	COG2766	serine protein kinase
S100072_RS04585	COG1846	Transcriptional regulator
S100072_RS04590	COG1566	PFAM secretion protein HlyD family protein
S100072_RS04595	COG2814	Major facilitator Superfamily
S100072_RS04600	COG0655	NAD(P)H dehydrogenase (quinone) activity
S100072_RS04615	COG1725	Transcriptional regulator
S100072_RS04620	COG1131	(ABC) transporter
S100072_RS04625	COG1131	(ABC) transporter
S100072_RS04630	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S100072_RS04635	COG1278	Cold shock
S100072_RS04645	COG1464	Belongs to the NlpA lipoprotein family
S100072_RS04650	COG3706	GGDEF domain
S100072_RS04655	COG1823	symporter activity
S100072_RS04675	COG5577	PFAM Coat F domain
S100072_RS04680	COG0737	Belongs to the 5'-nucleotidase family
S100072_RS04680	COG1525	nuclease
S100072_RS04680	COG4085	toxin activity
S100072_RS04685	COG3764	Sortase (surface protein transpeptidase)
S100072_RS04690	COG0564	pseudouridine synthase activity
S100072_RS04700	COG0517	IMP dehydrogenase activity
S100072_RS04705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S100072_RS04710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S100072_RS04710	COG3153	acetyltransferase
S100072_RS04715	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S100072_RS04720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S100072_RS04725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S100072_RS04735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
S100072_RS04740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S100072_RS04745	COG2203	Gaf domain
S100072_RS04745	COG4585	Histidine kinase
S100072_RS04750	COG2197	response regulator
S100072_RS04755	COG0431	NADPH-dependent FMN reductase
S100072_RS04770	COG1388	LysM domain
S100072_RS04770	COG0791	NLP P60 protein
S100072_RS04775	COG1959	2 iron, 2 sulfur cluster binding
S100072_RS04785	COG0668	transmembrane transport
S100072_RS04790	COG2719	SpoVR family
S100072_RS04795	COG1785	Belongs to the alkaline phosphatase family
S100072_RS04800	COG0791	NLP P60 protein
S100072_RS04800	COG1388	LysM domain
S100072_RS04810	COG0372	Belongs to the citrate synthase family
S100072_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS04820	COG0531	amino acid
S100072_RS04825	COG0733	neurotransmitter:sodium symporter activity
S100072_RS04840	COG1595	DNA-templated transcription, initiation
S100072_RS04845	COG0204	Acyl-transferase
S100072_RS04850	COG1253	flavin adenine dinucleotide binding
S100072_RS04855	COG0789	Transcriptional regulator
S100072_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S100072_RS04870	COG1253	flavin adenine dinucleotide binding
S100072_RS04875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S100072_RS04885	COG0584	glycerophosphoryl diester phosphodiesterase
S100072_RS04895	COG0668	transmembrane transport
S100072_RS04905	COG0726	polysaccharide deacetylase
S100072_RS04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S100072_RS04915	COG3226	Transcriptional regulator
S100072_RS04925	COG0589	response to stress
S100072_RS04930	COG1132	(ABC) transporter
S100072_RS04935	COG1132	(ABC) transporter
S100072_RS04940	COG0702	epimerase
S100072_RS04960	COG0189	ligase activity
S100072_RS04965	COG0189	ligase activity
S100072_RS04980	COG4335	DNA alkylation repair
S100072_RS04990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S100072_RS05000	COG0475	glutathione-regulated potassium exporter activity
S100072_RS05005	COG0490	domain, Protein
S100072_RS05025	COG4152	abc transporter atp-binding protein
S100072_RS05030	COG1668	transmembrane transport
S100072_RS05035	COG0420	3'-5' exonuclease activity
S100072_RS05040	COG4717	serine-type aminopeptidase activity
S100072_RS05055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S100072_RS05095	COG4980	gas vesicle protein
S100072_RS05110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S100072_RS05115	COG0537	adenosine 5'-monophosphoramidase activity
S100072_RS05120	COG1131	(ABC) transporter
S100072_RS05125	COG4473	ABC transporter
S100072_RS05135	COG1473	amidohydrolase
S100072_RS05140	COG3069	C4-dicarboxylate transmembrane transporter activity
S100072_RS05145	COG2329	Antibiotic biosynthesis monooxygenase
S100072_RS05150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S100072_RS05160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
S100072_RS05170	COG1309	transcriptional regulator
S100072_RS05175	COG1511	domain protein
S100072_RS05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S100072_RS05190	COG1363	Peptidase, m42
S100072_RS05195	COG1301	dicarboxylic acid transport
S100072_RS05205	COG1234	tRNA 3'-trailer cleavage
S100072_RS05210	COG0095	Lipoate-protein ligase
S100072_RS05215	COG0702	epimerase
S100072_RS05220	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS05230	COG0501	Belongs to the peptidase M48B family
S100072_RS05235	COG1404	Belongs to the peptidase S8 family
S100072_RS05250	COG0406	alpha-ribazole phosphatase activity
S100072_RS05255	COG0183	Belongs to the thiolase family
S100072_RS05260	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS05265	COG1268	BioY protein
S100072_RS05270	COG0840	transmembrane signaling receptor activity
S100072_RS05275	COG0723	plastoquinol--plastocyanin reductase activity
S100072_RS05275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S100072_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS05290	COG4903	ComK protein
S100072_RS05300	COG5646	InterPro IPR014922
S100072_RS05325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S100072_RS05340	COG0398	Pfam SNARE associated Golgi protein
S100072_RS05345	COG0681	Belongs to the peptidase S26 family
S100072_RS05350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S100072_RS05355	COG1846	Transcriptional regulator
S100072_RS05360	COG3180	Ammonia monooxygenase
S100072_RS05375	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S100072_RS05380	COG2323	membrane
S100072_RS05395	COG0420	3'-5' exonuclease activity
S100072_RS05400	COG0419	ATPase involved in DNA repair
S100072_RS05405	COG1403	HNH endonuclease
S100072_RS05445	COG0179	Fumarylacetoacetate (FAA) hydrolase
S100072_RS05470	COG0534	Mate efflux family protein
S100072_RS05475	COG2207	Transcriptional regulator
S100072_RS05475	COG1917	Cupin 2, conserved barrel domain protein
S100072_RS05480	COG1609	Transcriptional regulator
S100072_RS05485	COG0673	inositol 2-dehydrogenase activity
S100072_RS05490	COG2318	DinB family
S100072_RS05495	COG1279	arginine transmembrane transporter activity
S100072_RS05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S100072_RS05505	COG1357	PFAM Pentapeptide repeats (8 copies)
S100072_RS05510	COG2153	protein acetylation
S100072_RS05515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S100072_RS05515	COG0646	methionine synthase
S100072_RS05525	COG2996	Protein conserved in bacteria
S100072_RS05530	COG1744	ABC transporter substrate-binding protein PnrA-like
S100072_RS05535	COG0840	transmembrane signaling receptor activity
S100072_RS05540	COG2124	cytochrome p450
S100072_RS05555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS05570	COG0561	phosphatase activity
S100072_RS05575	COG1073	alpha beta
S100072_RS05580	COG2151	metal-sulfur cluster biosynthetic enzyme
S100072_RS05590	COG0277	FAD linked oxidase domain protein
S100072_RS05595	COG2271	Major facilitator Superfamily
S100072_RS05605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
S100072_RS05620	COG0505	Belongs to the CarA family
S100072_RS05625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S100072_RS05650	COG2267	carboxylic ester hydrolase activity
S100072_RS05660	COG1744	ABC transporter substrate-binding protein PnrA-like
S100072_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S100072_RS05680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S100072_RS05685	COG5504	Zn-dependent protease
S100072_RS05690	COG0444	Belongs to the ABC transporter superfamily
S100072_RS05695	COG4608	Belongs to the ABC transporter superfamily
S100072_RS05705	COG0601	transmembrane transport
S100072_RS05710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S100072_RS05720	COG0180	Tryptophanyl-tRNA synthetase
S100072_RS05725	COG4166	transmembrane transport
S100072_RS05730	COG0601	transmembrane transport
S100072_RS05735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S100072_RS05740	COG0444	Belongs to the ABC transporter superfamily
S100072_RS05745	COG4608	Belongs to the ABC transporter superfamily
S100072_RS05755	COG0456	acetyltransferase
S100072_RS05760	COG1393	Belongs to the ArsC family
S100072_RS05765	COG0861	Integral membrane protein TerC family
S100072_RS05770	COG4862	establishment of competence for transformation
S100072_RS05775	COG4469	Competence protein
S100072_RS05780	COG1164	Oligoendopeptidase f
S100072_RS05785	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S100072_RS05790	COG2346	COG2346, Truncated hemoglobins
S100072_RS05795	COG0741	lytic transglycosylase activity
S100072_RS05800	COG4116	CYTH
S100072_RS05810	COG2357	RelA SpoT domain protein
S100072_RS05815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S100072_RS05820	COG0564	pseudouridine synthase activity
S100072_RS05830	COG0475	glutathione-regulated potassium exporter activity
S100072_RS05830	COG0569	domain protein
S100072_RS05835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S100072_RS05840	COG0352	thiamine-phosphate diphosphorylase activity
S100072_RS05845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S100072_RS05850	COG2104	thiamine diphosphate biosynthetic process
S100072_RS05860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S100072_RS05865	COG0351	phosphomethylpyrimidine kinase
S100072_RS05870	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S100072_RS05925	COG0210	DNA helicase
S100072_RS05945	COG1131	(ABC) transporter
S100072_RS05955	COG2153	protein acetylation
S100072_RS05965	COG2382	esterase
S100072_RS05970	COG0626	cystathionine gamma-synthase activity
S100072_RS05975	COG0626	cystathionine gamma-synthase activity
S100072_RS05990	COG2856	Zn peptidase
S100072_RS06000	COG1396	sequence-specific DNA binding
S100072_RS06055	COG3935	DnaD domain protein
S100072_RS06060	COG1484	DNA-dependent DNA replication
S100072_RS06100	COG1595	DNA-templated transcription, initiation
S100072_RS06115	COG3591	Belongs to the peptidase S1B family
S100072_RS06120	COG5484	DNA packaging
S100072_RS06235	COG4824	toxin secretion phage lysis holin
S100072_RS06240	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS06240	COG1388	LysM domain
S100072_RS06240	COG5632	N-Acetylmuramoyl-L-alanine amidase
S100072_RS06250	COG5444	nuclease activity
S100072_RS06315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S100072_RS06315	COG2070	2-Nitropropane dioxygenase
S100072_RS06320	COG3425	synthase
S100072_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06340	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS06340	COG0300	oxidoreductase activity
S100072_RS06340	COG3321	synthase
S100072_RS06345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06345	COG3321	synthase
S100072_RS06345	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS06345	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06345	COG0300	oxidoreductase activity
S100072_RS06350	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS06350	COG3321	synthase
S100072_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06350	COG0300	oxidoreductase activity
S100072_RS06355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S100072_RS06355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S100072_RS06355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06355	COG3321	synthase
S100072_RS06360	COG0300	oxidoreductase activity
S100072_RS06360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06360	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06360	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS06360	COG3321	synthase
S100072_RS06365	COG3321	synthase
S100072_RS06365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS06365	COG4221	oxidoreductase activity
S100072_RS06395	COG0250	Participates in transcription elongation, termination and antitermination
S100072_RS06440	COG0537	adenosine 5'-monophosphoramidase activity
S100072_RS06450	COG2367	Beta-lactamase
S100072_RS06455	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S100072_RS06465	COG1846	Transcriptional regulator
S100072_RS06480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S100072_RS06485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S100072_RS06495	COG1447	Phosphotransferase system cellobiose-specific component IIA
S100072_RS06505	COG1349	DNA-binding transcription factor activity
S100072_RS06525	COG1285	pathogenesis
S100072_RS06540	COG2205	protein histidine kinase activity
S100072_RS06550	COG3383	formate dehydrogenase (NAD+) activity
S100072_RS06555	COG2427	Protein of unknown function (DUF1641)
S100072_RS06560	COG2124	cytochrome p450
S100072_RS06565	COG1819	glycosyl
S100072_RS06575	COG1587	Uroporphyrinogen-III synthase
S100072_RS06580	COG0390	transport system, permease component
S100072_RS06585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S100072_RS06590	COG0697	spore germination
S100072_RS06595	COG4297	protein containing double-stranded beta helix domain
S100072_RS06605	COG1252	NADH dehydrogenase
S100072_RS06620	COG1609	Transcriptional regulator
S100072_RS06625	COG0246	Mannitol dehydrogenase
S100072_RS06630	COG2721	sulfolactate sulfo-lyase activity
S100072_RS06635	COG0745	RESPONSE REGULATOR receiver
S100072_RS06640	COG2205	protein histidine kinase activity
S100072_RS06640	COG2770	Histidine kinase
S100072_RS06660	COG4585	Histidine kinase
S100072_RS06665	COG2197	response regulator
S100072_RS06690	COG0730	response to heat
S100072_RS06695	COG2318	DinB family
S100072_RS06700	COG0457	Tetratricopeptide repeat
S100072_RS06710	COG5632	N-Acetylmuramoyl-L-alanine amidase
S100072_RS06710	COG1388	LysM domain
S100072_RS06710	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS06720	COG4195	phage-related replication protein
S100072_RS06725	COG2856	Zn peptidase
S100072_RS06730	COG1396	sequence-specific DNA binding
S100072_RS06740	COG1522	sequence-specific DNA binding
S100072_RS06745	COG1484	DNA-dependent DNA replication
S100072_RS06760	COG1595	DNA-templated transcription, initiation
S100072_RS06765	COG4193	domain, Protein
S100072_RS06800	COG5632	N-Acetylmuramoyl-L-alanine amidase
S100072_RS06800	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS06815	COG0306	phosphate transporter
S100072_RS06820	COG1392	Phosphate transport regulator
S100072_RS06825	COG0531	amino acid
S100072_RS06830	COG0346	lactoylglutathione lyase activity
S100072_RS06835	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S100072_RS06840	COG0463	Glycosyl transferase, family 2
S100072_RS06845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S100072_RS06850	COG0477	Major facilitator Superfamily
S100072_RS06855	COG2362	D-Aminopeptidase
S100072_RS06860	COG0601	transmembrane transport
S100072_RS06865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S100072_RS06870	COG0444	Belongs to the ABC transporter superfamily
S100072_RS06875	COG4166	transmembrane transport
S100072_RS06880	COG1619	proteins homologs of microcin C7 resistance protein MccF
S100072_RS06890	COG0791	NLP P60 protein
S100072_RS06900	COG2706	6-phosphogluconolactonase activity
S100072_RS06905	COG1834	amidinotransferase
S100072_RS06910	COG1607	acyl-coa hydrolase
S100072_RS06915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S100072_RS06920	COG2076	Multidrug Resistance protein
S100072_RS06925	COG2076	Multidrug Resistance protein
S100072_RS06930	COG0788	formyltetrahydrofolate deformylase activity
S100072_RS06935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S100072_RS06945	COG1764	response to oxidative stress
S100072_RS06950	COG1846	Transcriptional regulator
S100072_RS06955	COG1764	response to oxidative stress
S100072_RS06970	COG0463	Glycosyl transferase, family 2
S100072_RS06970	COG0457	Tetratricopeptide repeat
S100072_RS06980	COG2814	Major facilitator Superfamily
S100072_RS06985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S100072_RS06995	COG1404	Belongs to the peptidase S8 family
S100072_RS07000	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS07005	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S100072_RS07010	COG1122	ATPase activity
S100072_RS07015	COG4721	ABC-type cobalt transport system, permease component
S100072_RS07020	COG1388	LysM domain
S100072_RS07020	COG3858	chitin binding
S100072_RS07040	COG2239	Acts as a magnesium transporter
S100072_RS07045	COG0789	Transcriptional regulator
S100072_RS07060	COG1846	Transcriptional regulator
S100072_RS07065	COG0726	polysaccharide deacetylase
S100072_RS07070	COG3285	dna ligase
S100072_RS07070	COG1793	dna ligase
S100072_RS07075	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S100072_RS07080	COG0586	Pfam SNARE associated Golgi protein
S100072_RS07085	COG0861	Integral membrane protein TerC family
S100072_RS07090	COG1191	sigma factor activity
S100072_RS07115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S100072_RS07120	COG2323	membrane
S100072_RS07130	COG3594	Acyltransferase
S100072_RS07135	COG5002	protein histidine kinase activity
S100072_RS07140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S100072_RS07155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S100072_RS07160	COG0436	Aminotransferase
S100072_RS07190	COG3852	Histidine kinase
S100072_RS07195	COG1846	Transcriptional regulator
S100072_RS07200	COG1360	Flagellar Motor Protein
S100072_RS07205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S100072_RS07210	COG0542	response to heat
S100072_RS07220	COG3949	Membrane
S100072_RS07235	COG0720	synthase
S100072_RS07240	COG0602	queuosine metabolic process
S100072_RS07245	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
S100072_RS07250	COG1733	regulation of RNA biosynthetic process
S100072_RS07255	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS07275	COG4873	Protein conserved in bacteria
S100072_RS07285	COG3773	Cell wall hydrolase
S100072_RS07290	COG2244	polysaccharide biosynthetic process
S100072_RS07295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS07300	COG2217	Heavy metal translocating P-type atpase
S100072_RS07305	COG0006	proline dipeptidase activity
S100072_RS07310	COG1609	Transcriptional regulator
S100072_RS07315	COG3711	transcriptional antiterminator
S100072_RS07320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S100072_RS07320	COG2190	(PTS) system
S100072_RS07320	COG1263	PTS System
S100072_RS07325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS07330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S100072_RS07340	COG1533	DNA photolyase activity
S100072_RS07345	COG0840	transmembrane signaling receptor activity
S100072_RS07350	COG2084	Dehydrogenase
S100072_RS07355	COG2340	Cysteine-rich secretory protein family
S100072_RS07360	COG0768	penicillin binding
S100072_RS07365	COG4191	Histidine kinase
S100072_RS07370	COG0436	Aminotransferase
S100072_RS07380	COG0784	Response regulator, receiver
S100072_RS07380	COG0835	chemotaxis
S100072_RS07390	COG2814	Major facilitator Superfamily
S100072_RS07395	COG1376	ErfK ybiS ycfS ynhG family protein
S100072_RS07400	COG1408	metallophosphoesterase
S100072_RS07405	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS07415	COG2200	EAL domain
S100072_RS07420	COG4703	Protein of unknown function (DUF1797)
S100072_RS07425	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S100072_RS07435	COG0517	IMP dehydrogenase activity
S100072_RS07440	COG0583	DNA-binding transcription factor activity
S100072_RS07445	COG0716	FMN binding
S100072_RS07455	COG0716	FMN binding
S100072_RS07475	COG0668	transmembrane transport
S100072_RS07480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS07500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S100072_RS07505	COG0303	'Molybdopterin
S100072_RS07510	COG1763	Mo-molybdopterin cofactor biosynthetic process
S100072_RS07515	COG0314	molybdopterin synthase activity
S100072_RS07520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S100072_RS07530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S100072_RS07535	COG1136	(ABC) transporter
S100072_RS07540	COG0577	efflux transmembrane transporter activity
S100072_RS07545	COG1349	DNA-binding transcription factor activity
S100072_RS07550	COG1105	Belongs to the carbohydrate kinase PfkB family
S100072_RS07555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S100072_RS07555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S100072_RS07555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS07560	COG0681	Belongs to the peptidase S26 family
S100072_RS07570	COG0488	(ABC) transporter
S100072_RS07575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S100072_RS07580	COG2309	aminopeptidase activity
S100072_RS07600	COG2002	toxin-antitoxin pair type II binding
S100072_RS07605	COG3852	Histidine kinase
S100072_RS07610	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S100072_RS07610	COG2105	PFAM AIG2 family protein
S100072_RS07615	COG0569	domain protein
S100072_RS07625	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S100072_RS07635	COG0561	phosphatase activity
S100072_RS07640	COG0242	peptide deformylase activity
S100072_RS07650	COG0497	DNA recombination
S100072_RS07670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S100072_RS07670	COG0300	oxidoreductase activity
S100072_RS07670	COG3321	synthase
S100072_RS07670	COG4221	oxidoreductase activity
S100072_RS07700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S100072_RS07705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S100072_RS07710	COG0022	dehydrogenase e1 component
S100072_RS07715	COG0508	dehydrogenase complex catalyzes the overall conversion of
S100072_RS07720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S100072_RS07725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS07740	COG1982	Orn Lys Arg decarboxylase major
S100072_RS07765	COG0483	inositol monophosphate 1-phosphatase activity
S100072_RS07775	COG3227	Zinc metalloprotease (Elastase)
S100072_RS07800	COG1217	gtp-binding protein TYPA
S100072_RS07810	COG4896	Protein conserved in bacteria
S100072_RS07820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S100072_RS07825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S100072_RS07830	COG2066	Belongs to the glutaminase family
S100072_RS07840	COG0772	Belongs to the SEDS family
S100072_RS07845	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
S100072_RS07860	COG2010	Cytochrome c
S100072_RS07860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S100072_RS07865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S100072_RS07870	COG1845	cytochrome c oxidase, subunit III
S100072_RS07875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S100072_RS07880	COG3336	cytochrome c oxidase
S100072_RS07890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S100072_RS07895	COG2340	Cysteine-rich secretory protein family
S100072_RS07910	COG3679	Belongs to the UPF0342 family
S100072_RS07925	COG0742	ribosomal rna small subunit methyltransferase
S100072_RS07935	COG3314	Sporulation integral membrane protein YlbJ
S100072_RS07940	COG1752	Esterase of the alpha-beta hydrolase superfamily
S100072_RS07945	COG3480	Lon protease (S16) C-terminal proteolytic domain
S100072_RS07955	COG1399	metal-binding, possibly nucleic acid-binding protein
S100072_RS07975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S100072_RS07995	COG4839	cell division protein FtsL
S100072_RS08000	COG0768	penicillin binding
S100072_RS08005	COG0768	penicillin binding
S100072_RS08025	COG0772	Belongs to the SEDS family
S100072_RS08040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S100072_RS08045	COG0849	cell division
S100072_RS08050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S100072_RS08055	COG4412	M6 family metalloprotease domain protein
S100072_RS08055	COG1404	Belongs to the peptidase S8 family
S100072_RS08065	COG1191	sigma factor activity
S100072_RS08070	COG1191	sigma factor activity
S100072_RS08075	COG1119	ATPase activity
S100072_RS08080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S100072_RS08085	COG1873	PFAM PRC-barrel domain
S100072_RS08090	COG1496	oxidoreductase activity
S100072_RS08095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S100072_RS08105	COG0762	integral membrane protein
S100072_RS08110	COG2302	S4 RNA-binding domain
S100072_RS08115	COG3599	regulation of cell shape
S100072_RS08125	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S100072_RS08130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S100072_RS08140	COG0564	pseudouridine synthase activity
S100072_RS08150	COG2233	PERMEase
S100072_RS08160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S100072_RS08165	COG0505	Belongs to the CarA family
S100072_RS08170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S100072_RS08185	COG0284	orotidine-5'-phosphate decarboxylase activity
S100072_RS08190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S100072_RS08200	COG0306	phosphate transporter
S100072_RS08215	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S100072_RS08220	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
S100072_RS08225	COG1648	precorrin-2 dehydrogenase activity
S100072_RS08235	COG1293	RNA-binding protein homologous to eukaryotic snRNP
S100072_RS08240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S100072_RS08245	COG1561	YicC-like family, N-terminal region
S100072_RS08255	COG0194	GDP metabolic process
S100072_RS08270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S100072_RS08275	COG0242	peptide deformylase activity
S100072_RS08285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S100072_RS08285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S100072_RS08295	COG0631	protein serine/threonine phosphatase activity
S100072_RS08300	COG0515	serine threonine protein kinase
S100072_RS08300	COG2815	serine threonine protein kinase
S100072_RS08310	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S100072_RS08315	COG1564	THIamine pyrophosphokinase
S100072_RS08330	COG1302	Protein conserved in bacteria
S100072_RS08335	COG1461	Dihydroxyacetone kinase
S100072_RS08340	COG1760	l-serine dehydratase
S100072_RS08345	COG1760	l-serine dehydratase
S100072_RS08350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S100072_RS08365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S100072_RS08370	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS08385	COG1196	nuclear chromosome segregation
S100072_RS08390	COG0552	protein localization to endoplasmic reticulum
S100072_RS08405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S100072_RS08415	COG1837	Belongs to the UPF0109 family
S100072_RS08440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S100072_RS08465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S100072_RS08475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S100072_RS08485	COG4974	Belongs to the 'phage' integrase family
S100072_RS08505	COG1815	bacterial-type flagellum-dependent cell motility
S100072_RS08510	COG1558	bacterial-type flagellum-dependent cell motility
S100072_RS08515	COG1677	Flagellar hook-basal body complex protein FliE
S100072_RS08520	COG1766	The M ring may be actively involved in energy transduction
S100072_RS08525	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S100072_RS08530	COG1317	bacterial-type flagellum organization
S100072_RS08535	COG1157	protein secretion by the type III secretion system
S100072_RS08540	COG2882	bacterial-type flagellum organization
S100072_RS08545	COG3334	PFAM MgtE intracellular
S100072_RS08555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S100072_RS08560	COG4786	Flagellar basal body rod
S100072_RS08565	COG1582	Flagellar protein (FlbD)
S100072_RS08570	COG1580	Controls the rotational direction of flagella during chemotaxis
S100072_RS08575	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S100072_RS08580	COG1776	CheC inhibitor of MCP methylation
S100072_RS08580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S100072_RS08585	COG2201	protein-glutamate methylesterase activity
S100072_RS08590	COG3190	flagellar
S100072_RS08595	COG1338	Plays a role in the flagellum-specific transport system
S100072_RS08600	COG1987	bacterial-type flagellum assembly
S100072_RS08605	COG1684	flagellar biosynthetic protein fliR
S100072_RS08610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S100072_RS08615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S100072_RS08625	COG0455	bacterial-type flagellum organization
S100072_RS08630	COG2201	protein-glutamate methylesterase activity
S100072_RS08635	COG0643	Histidine kinase
S100072_RS08635	COG2198	Histidine kinase
S100072_RS08640	COG0835	chemotaxis
S100072_RS08645	COG1776	CheC inhibitor of MCP methylation
S100072_RS08655	COG1191	sigma factor activity
S100072_RS08685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S100072_RS08690	COG4589	Belongs to the CDS family
S100072_RS08700	COG0750	zinc metalloprotease
S100072_RS08720	COG0195	Participates in both transcription termination and antitermination
S100072_RS08725	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S100072_RS08730	COG1358	cellular component organization or biogenesis
S100072_RS08740	COG1550	Protein conserved in bacteria
S100072_RS08755	COG0196	riboflavin kinase activity
S100072_RS08770	COG0726	polysaccharide deacetylase
S100072_RS08775	COG0612	Peptidase, M16
S100072_RS08780	COG1873	PFAM PRC-barrel domain
S100072_RS08785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S100072_RS08790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S100072_RS08795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S100072_RS08800	COG0527	aspartate kinase activity
S100072_RS08810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S100072_RS08815	COG0740	serine-type endopeptidase activity
S100072_RS08825	COG4980	gas vesicle protein
S100072_RS08825	COG1674	ftsk spoiiie
S100072_RS08830	COG2188	Transcriptional regulator
S100072_RS08835	COG2814	Major facilitator Superfamily
S100072_RS08840	COG1846	Transcriptional regulator
S100072_RS08845	COG1033	growth of symbiont in host cell
S100072_RS08845	COG2409	Drug exporters of the RND superfamily
S100072_RS08850	COG0612	Peptidase, M16
S100072_RS08855	COG0612	Peptidase, M16
S100072_RS08860	COG0300	oxidoreductase activity
S100072_RS08875	COG1426	Protein conserved in bacteria
S100072_RS08880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S100072_RS08905	COG1692	metallophosphoesterase
S100072_RS08910	COG2359	stage V sporulation protein S
S100072_RS08930	COG4550	Control of competence regulator ComK, YlbF/YmcA
S100072_RS08980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S100072_RS08985	COG3425	synthase
S100072_RS08990	COG1024	Enoyl-CoA hydratase
S100072_RS08995	COG1024	Enoyl-CoA hydratase
S100072_RS09005	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S100072_RS09005	COG3321	synthase
S100072_RS09005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S100072_RS09005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
S100072_RS09010	COG2124	cytochrome p450
S100072_RS09015	COG3209	COG3209 Rhs family protein
S100072_RS09020	COG3619	membrane
S100072_RS09030	COG1404	Belongs to the peptidase S8 family
S100072_RS09040	COG4195	phage-related replication protein
S100072_RS09045	COG1764	response to oxidative stress
S100072_RS09055	COG2076	Multidrug Resistance protein
S100072_RS09095	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S100072_RS09100	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S100072_RS09105	COG4112	unkown
S100072_RS09110	COG0860	N-Acetylmuramoyl-L-alanine amidase
S100072_RS09120	COG0464	growth
S100072_RS09125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S100072_RS09130	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S100072_RS09135	COG0789	Transcriptional regulator
S100072_RS09140	COG0174	glutamine synthetase
S100072_RS09175	COG3507	Belongs to the glycosyl hydrolase 43 family
S100072_RS09195	COG3848	Pyruvate phosphate dikinase
S100072_RS09195	COG0574	Belongs to the PEP-utilizing enzyme family
S100072_RS09220	COG2378	regulation of single-species biofilm formation
S100072_RS09225	COG2318	DinB family
S100072_RS09230	COG1064	alcohol dehydrogenase
S100072_RS09250	COG5444	nuclease activity
S100072_RS09315	COG3397	chitin binding
S100072_RS09330	COG5434	Belongs to the glycosyl hydrolase 28 family
S100072_RS09335	COG0756	dUTP diphosphatase activity
S100072_RS09340	COG4195	phage-related replication protein
S100072_RS09370	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S100072_RS09380	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
S100072_RS09400	COG0785	Cytochrome C biogenesis protein
S100072_RS09405	COG2201	protein-glutamate methylesterase activity
S100072_RS09410	COG4846	Membrane protein involved in cytochrome C biogenesis
S100072_RS09420	COG0071	Belongs to the small heat shock protein (HSP20) family
S100072_RS09435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S100072_RS09440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS09460	COG0824	Thioesterase
S100072_RS09470	COG4841	protein insertion into membrane
S100072_RS09480	COG1832	CoA-binding protein
S100072_RS09490	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S100072_RS09500	COG1115	amino acid carrier protein
S100072_RS09510	COG1063	alcohol dehydrogenase
S100072_RS09515	COG0800	Aldolase
S100072_RS09520	COG1312	Catalyzes the dehydration of D-mannonate
S100072_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS09530	COG1609	Transcriptional regulator
S100072_RS09535	COG2271	Major facilitator Superfamily
S100072_RS09570	COG2205	protein histidine kinase activity
S100072_RS09575	COG0745	RESPONSE REGULATOR receiver
S100072_RS09585	COG3507	Belongs to the glycosyl hydrolase 43 family
S100072_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS09615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S100072_RS09620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S100072_RS09625	COG2610	gluconate transmembrane transporter activity
S100072_RS09630	COG2124	cytochrome p450
S100072_RS09650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S100072_RS09660	COG2246	polysaccharide biosynthetic process
S100072_RS09665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S100072_RS09670	COG0586	Pfam SNARE associated Golgi protein
S100072_RS09675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S100072_RS09680	COG1024	Enoyl-CoA hydratase
S100072_RS09685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S100072_RS09690	COG0511	ligase activity, forming carbon-carbon bonds
S100072_RS09695	COG0439	Biotin carboxylase
S100072_RS09700	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS09705	COG1960	acyl-CoA dehydrogenase activity
S100072_RS09710	COG1649	PFAM Uncharacterised BCR, COG1649
S100072_RS09720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS09720	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S100072_RS09735	COG2027	D-alanyl-D-alanine carboxypeptidase
S100072_RS09740	COG2017	converts alpha-aldose to the beta-anomer
S100072_RS09745	COG0534	Mate efflux family protein
S100072_RS09760	COG0582	viral genome integration into host DNA
S100072_RS09765	COG0166	Belongs to the GPI family
S100072_RS09770	COG0405	Gamma-glutamyltransferase
S100072_RS09780	COG0640	Transcriptional regulator
S100072_RS09785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S100072_RS09795	COG0604	alcohol dehydrogenase
S100072_RS09805	COG0493	'glutamate synthase
S100072_RS09810	COG0067	glutamate synthase
S100072_RS09810	COG0070	glutamate synthase
S100072_RS09810	COG0069	glutamate synthase activity
S100072_RS09815	COG0583	DNA-binding transcription factor activity
S100072_RS09820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S100072_RS09840	COG0300	oxidoreductase activity
S100072_RS09845	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S100072_RS09855	COG2814	Major facilitator Superfamily
S100072_RS09860	COG1070	Carbohydrate kinase
S100072_RS09865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S100072_RS09870	COG0243	molybdopterin cofactor binding
S100072_RS09900	COG5444	nuclease activity
S100072_RS09905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS09910	COG2207	Transcriptional regulator
S100072_RS09910	COG0662	Cupin 2, conserved barrel domain protein
S100072_RS09915	COG1309	transcriptional regulator
S100072_RS09930	COG0640	Transcriptional regulator
S100072_RS09935	COG0741	lytic transglycosylase activity
S100072_RS09940	COG2322	membrane
S100072_RS09955	COG1619	proteins homologs of microcin C7 resistance protein MccF
S100072_RS09970	COG0514	ATP-dependent DNA helicase (RecQ)
S100072_RS09980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S100072_RS09985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S100072_RS10000	COG0071	Belongs to the small heat shock protein (HSP20) family
S100072_RS10030	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS10035	COG1657	PFAM Prenyltransferase squalene oxidase
S100072_RS10040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S100072_RS10050	COG0385	Bile acid
S100072_RS10055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S100072_RS10060	COG0508	dehydrogenase complex catalyzes the overall conversion of
S100072_RS10070	COG4548	von Willebrand factor, type A
S100072_RS10075	COG0714	Associated with various cellular activities
S100072_RS10080	COG2032	superoxide dismutase activity
S100072_RS10085	COG1388	LysM domain
S100072_RS10085	COG0791	NLP P60 protein
S100072_RS10090	COG1819	glycosyl
S100072_RS10095	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S100072_RS10100	COG0534	Mate efflux family protein
S100072_RS10105	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS10110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S100072_RS10115	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S100072_RS10125	COG2962	Rard protein
S100072_RS10140	COG1942	4-Oxalocrotonate Tautomerase
S100072_RS10155	COG0778	Nitroreductase
S100072_RS10160	COG0400	carboxylic ester hydrolase activity
S100072_RS10165	COG0346	lactoylglutathione lyase activity
S100072_RS10190	COG2188	Transcriptional regulator
S100072_RS10195	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS10195	COG0793	Belongs to the peptidase S41A family
S100072_RS10200	COG2226	methyltransferase
S100072_RS10210	COG1876	peptidase activity
S100072_RS10230	COG0671	phosphoesterase, PA-phosphatase related
S100072_RS10260	COG1509	lysine 2,3-aminomutase activity
S100072_RS10265	COG0456	acetyltransferase
S100072_RS10275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S100072_RS10280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S100072_RS10285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S100072_RS10295	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
S100072_RS10305	COG0456	acetyltransferase
S100072_RS10310	COG0463	Glycosyl transferase, family 2
S100072_RS10325	COG4641	Protein conserved in bacteria
S100072_RS10335	COG1086	Polysaccharide biosynthesis protein
S100072_RS10350	COG1846	Transcriptional regulator
S100072_RS10355	COG4698	Protein conserved in bacteria
S100072_RS10360	COG2755	lipolytic protein G-D-S-L family
S100072_RS10365	COG1999	signal sequence binding
S100072_RS10375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S100072_RS10380	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S100072_RS10385	COG1272	protein, Hemolysin III
S100072_RS10390	COG0204	Acyl-transferase
S100072_RS10395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S100072_RS10410	COG2136	Putative SAM-dependent methyltransferase
S100072_RS10410	COG2521	methyltransferase
S100072_RS10425	COG1413	lyase activity
S100072_RS10430	COG1418	mRNA catabolic process
S100072_RS10435	COG0386	Belongs to the glutathione peroxidase family
S100072_RS10445	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S100072_RS10455	COG1278	Cold shock
S100072_RS10475	COG0328	RNA-DNA hybrid ribonuclease activity
S100072_RS10480	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S100072_RS10485	COG0328	RNA-DNA hybrid ribonuclease activity
S100072_RS10510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S100072_RS10540	COG1335	isochorismatase
S100072_RS10550	COG2233	PERMEase
S100072_RS10560	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S100072_RS10565	COG1199	ATP-dependent helicase activity
S100072_RS10580	COG0116	Belongs to the methyltransferase superfamily
S100072_RS10610	COG3359	exonuclease
S100072_RS10615	COG1111	helicase
S100072_RS10615	COG1205	dead DEAH box helicase
S100072_RS10620	COG2190	(PTS) system
S100072_RS10625	COG0071	Belongs to the small heat shock protein (HSP20) family
S100072_RS10665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S100072_RS10665	COG4499	WXG100 protein secretion system (Wss), protein YukC
S100072_RS10675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S100072_RS10680	COG3935	DnaD domain protein
S100072_RS10690	COG0436	Aminotransferase
S100072_RS10695	COG5353	protein conserved in bacteria
S100072_RS10705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
S100072_RS10705	COG1199	ATP-dependent helicase activity
S100072_RS10735	COG0438	transferase activity, transferring glycosyl groups
S100072_RS10740	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S100072_RS10755	COG1694	Mazg nucleotide pyrophosphohydrolase
S100072_RS10760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS10765	COG2140	Oxalate decarboxylase
S100072_RS10775	COG4347	Protein of unknown function (DUF1405)
S100072_RS10780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S100072_RS10780	COG2010	Cytochrome c
S100072_RS10785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S100072_RS10815	COG0287	Prephenate dehydrogenase
S100072_RS10850	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S100072_RS10855	COG4401	Chorismate mutase type I
S100072_RS10870	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
S100072_RS10875	COG0105	UTP biosynthetic process
S100072_RS10880	COG0142	geranyltranstransferase activity
S100072_RS10890	COG0142	geranyltranstransferase activity
S100072_RS10905	COG0776	regulation of translation
S100072_RS10910	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S100072_RS10950	COG0539	negative regulation of cytoplasmic translation
S100072_RS10960	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S100072_RS10965	COG2959	enzyme of heme biosynthesis
S100072_RS10970	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS10970	COG3773	Cell wall hydrolase
S100072_RS10975	COG2339	peptidase activity
S100072_RS10980	COG0492	ferredoxin-NADP+ reductase activity
S100072_RS10985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S100072_RS10990	COG4862	establishment of competence for transformation
S100072_RS10995	COG1408	metallophosphoesterase
S100072_RS11005	COG1388	LysM domain
S100072_RS11010	COG1266	CAAX protease self-immunity
S100072_RS11015	COG0514	ATP-dependent DNA helicase (RecQ)
S100072_RS11020	COG4955	Helix-turn-helix domain
S100072_RS11025	COG1141	Ferredoxin
S100072_RS11030	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S100072_RS11035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
S100072_RS11045	COG1595	DNA-templated transcription, initiation
S100072_RS11050	COG5002	protein histidine kinase activity
S100072_RS11055	COG0745	RESPONSE REGULATOR receiver
S100072_RS11060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S100072_RS11065	COG1333	cytochrome c biogenesis protein
S100072_RS11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS11075	COG1187	pseudouridine synthase activity
S100072_RS11080	COG0700	Nucleoside recognition
S100072_RS11085	COG2715	membrane protein required for spore maturation
S100072_RS11090	COG1686	Belongs to the peptidase S11 family
S100072_RS11115	COG1547	Domain of unknown function (DUF309)
S100072_RS11125	COG0456	acetyltransferase
S100072_RS11140	COG0307	riboflavin synthase, alpha
S100072_RS11145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S100072_RS11145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S100072_RS11155	COG0681	Belongs to the peptidase S26 family
S100072_RS11165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S100072_RS11170	COG4086	secreted protein
S100072_RS11175	COG0019	diaminopimelate decarboxylase activity
S100072_RS11180	COG0697	spore germination
S100072_RS11215	COG1191	sigma factor activity
S100072_RS11225	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS11230	COG1686	Belongs to the peptidase S11 family
S100072_RS11235	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S100072_RS11240	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S100072_RS11245	COG4974	Belongs to the 'phage' integrase family
S100072_RS11255	COG0735	belongs to the Fur family
S100072_RS11260	COG1300	Membrane
S100072_RS11275	COG0281	malic enzyme
S100072_RS11280	COG1757	Na H antiporter
S100072_RS11285	COG1027	Aspartate ammonia-lyase
S100072_RS11290	COG0252	asparaginase activity
S100072_RS11295	COG1396	sequence-specific DNA binding
S100072_RS11300	COG1379	DNA repair
S100072_RS11305	COG0494	nUDIX hydrolase
S100072_RS11315	COG0667	Aldo Keto reductase
S100072_RS11325	COG1073	alpha beta
S100072_RS11335	COG4918	Iron-sulphur cluster biosynthesis
S100072_RS11340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
S100072_RS11340	COG0456	acetyltransferase
S100072_RS11345	COG2329	Antibiotic biosynthesis monooxygenase
S100072_RS11350	COG0456	acetyltransferase
S100072_RS11355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
S100072_RS11370	COG0628	permease
S100072_RS11380	COG0346	lactoylglutathione lyase activity
S100072_RS11390	COG3048	D-serine ammonia-lyase activity
S100072_RS11395	COG0300	oxidoreductase activity
S100072_RS11400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S100072_RS11405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S100072_RS11410	COG1024	Enoyl-CoA hydratase
S100072_RS11415	COG3425	synthase
S100072_RS11420	COG2124	cytochrome p450
S100072_RS11440	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS11440	COG0300	oxidoreductase activity
S100072_RS11440	COG3321	synthase
S100072_RS11440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS11440	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS11450	COG3321	synthase
S100072_RS11450	COG0300	oxidoreductase activity
S100072_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS11450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS11450	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS11455	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS11455	COG3321	synthase
S100072_RS11455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S100072_RS11455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS11455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S100072_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS11465	COG0318	PFAM AMP-dependent synthetase and ligase
S100072_RS11480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S100072_RS11480	COG2070	2-Nitropropane dioxygenase
S100072_RS11485	COG0250	Participates in transcription elongation, termination and antitermination
S100072_RS11510	COG0596	Alpha beta hydrolase
S100072_RS11525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S100072_RS11530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S100072_RS11545	COG0706	membrane insertase activity
S100072_RS11550	COG2195	Cleaves the N-terminal amino acid of tripeptides
S100072_RS11555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S100072_RS11560	COG0346	lactoylglutathione lyase activity
S100072_RS11565	COG1376	ErfK ybiS ycfS ynhG family protein
S100072_RS11570	COG4129	membrane
S100072_RS11575	COG1126	abc transporter atp-binding protein
S100072_RS11580	COG0765	amino acid transport
S100072_RS11585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S100072_RS11600	COG1597	lipid kinase activity
S100072_RS11605	COG0508	dehydrogenase complex catalyzes the overall conversion of
S100072_RS11610	COG0022	dehydrogenase e1 component
S100072_RS11615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S100072_RS11620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S100072_RS11625	COG3426	butyrate kinase activity
S100072_RS11630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S100072_RS11635	COG0280	phosphate acetyltransferase
S100072_RS11640	COG3290	protein histidine kinase activity
S100072_RS11640	COG3829	transcription factor binding
S100072_RS11650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S100072_RS11655	COG2079	MmgE PrpD family protein
S100072_RS11660	COG0372	Belongs to the citrate synthase family
S100072_RS11670	COG1250	3-hydroxyacyl-CoA dehydrogenase
S100072_RS11675	COG0183	Belongs to the thiolase family
S100072_RS11685	COG0860	N-Acetylmuramoyl-L-alanine amidase
S100072_RS11720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S100072_RS11725	COG0745	RESPONSE REGULATOR receiver
S100072_RS11730	COG0750	zinc metalloprotease
S100072_RS11745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S100072_RS11755	COG0142	geranyltranstransferase activity
S100072_RS11765	COG1570	exodeoxyribonuclease VII activity
S100072_RS11780	COG1302	Protein conserved in bacteria
S100072_RS11785	COG0439	Biotin carboxylase
S100072_RS11790	COG0511	ligase activity, forming carbon-carbon bonds
S100072_RS11830	COG3854	ATPases associated with a variety of cellular activities
S100072_RS11845	COG0006	proline dipeptidase activity
S100072_RS11855	COG3872	metal-dependent enzyme
S100072_RS11880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S100072_RS11900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S100072_RS11915	COG1396	sequence-specific DNA binding
S100072_RS11925	COG0681	Belongs to the peptidase S26 family
S100072_RS11950	COG4940	Competence protein ComGF
S100072_RS11960	COG4970	Tfp pilus assembly protein FimT
S100072_RS11965	COG4537	Required for transformation and DNA binding
S100072_RS11970	COG1459	type II secretion system
S100072_RS11980	COG0598	Magnesium transport protein CorA
S100072_RS11990	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS12000	COG1393	Belongs to the ArsC family
S100072_RS12010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S100072_RS12020	COG0011	TIGRFAM Protein of
S100072_RS12030	COG2866	Carboxypeptidase
S100072_RS12035	COG1940	carbohydrate kinase activity
S100072_RS12040	COG4483	Protein conserved in bacteria
S100072_RS12045	COG1757	Na H antiporter
S100072_RS12055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S100072_RS12070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S100072_RS12075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S100072_RS12080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S100072_RS12085	COG0581	inorganic phosphate transmembrane transporter activity
S100072_RS12095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S100072_RS12100	COG0768	penicillin binding
S100072_RS12105	COG0477	Major facilitator Superfamily
S100072_RS12110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S100072_RS12115	COG2839	Protein conserved in bacteria
S100072_RS12120	COG5521	maltodextrose utilization protein MalA
S100072_RS12125	COG1388	LysM domain
S100072_RS12135	COG4709	membrane
S100072_RS12140	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S100072_RS12145	COG0735	belongs to the Fur family
S100072_RS12165	COG0513	Belongs to the DEAD box helicase family
S100072_RS12180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S100072_RS12185	COG2384	SAM-dependent methyltransferase
S100072_RS12190	COG2010	Cytochrome c
S100072_RS12195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S100072_RS12200	COG0358	DNA primase activity
S100072_RS12215	COG0517	IMP dehydrogenase activity
S100072_RS12220	COG0751	glycine-tRNA ligase activity
S100072_RS12240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S100072_RS12245	COG0295	cytidine deaminase activity
S100072_RS12250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S100072_RS12260	COG1480	7TM receptor with intracellular HD hydrolase
S100072_RS12265	COG1702	phosphate starvation-inducible protein PhoH
S100072_RS12270	COG0561	phosphatase activity
S100072_RS12285	COG4864	UPF0365 protein
S100072_RS12290	COG1030	water channel activity
S100072_RS12295	COG1610	YqeY-like protein
S100072_RS12305	COG1283	sodium-dependent phosphate transmembrane transporter activity
S100072_RS12310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S100072_RS12315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S100072_RS12345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S100072_RS12360	COG0860	N-Acetylmuramoyl-L-alanine amidase
S100072_RS12375	COG1466	dna polymerase III delta subunit
S100072_RS12390	COG2333	competence protein COMEC
S100072_RS12390	COG0658	competence protein
S100072_RS12395	COG2131	deaminase
S100072_RS12400	COG1555	photosystem II stabilization
S100072_RS12400	COG1596	polysaccharide export
S100072_RS12405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S100072_RS12410	COG2226	methyltransferase
S100072_RS12415	COG0799	negative regulation of ribosome biogenesis
S100072_RS12420	COG1713	HD superfamily hydrolase involved in NAD metabolism
S100072_RS12430	COG1534	Rna-binding protein
S100072_RS12435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S100072_RS12440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S100072_RS12445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S100072_RS12455	COG2755	lipolytic protein G-D-S-L family
S100072_RS12465	COG0398	Pfam SNARE associated Golgi protein
S100072_RS12500	COG5444	nuclease activity
S100072_RS12505	COG4282	regulation of fungal-type cell wall biogenesis
S100072_RS12520	COG3708	Transcriptional regulator
S100072_RS12520	COG2207	Transcriptional regulator
S100072_RS12525	COG0583	DNA-binding transcription factor activity
S100072_RS12540	COG0642	Histidine kinase
S100072_RS12540	COG5002	protein histidine kinase activity
S100072_RS12545	COG0745	RESPONSE REGULATOR receiver
S100072_RS12550	COG2311	Membrane
S100072_RS12565	COG0563	adenylate kinase activity
S100072_RS12575	COG2814	Major facilitator Superfamily
S100072_RS12585	COG0456	acetyltransferase
S100072_RS12590	COG2318	DinB family
S100072_RS12600	COG0561	phosphatase activity
S100072_RS12605	COG0561	phosphatase activity
S100072_RS12615	COG1482	cell wall glycoprotein biosynthetic process
S100072_RS12620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS12620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S100072_RS12620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S100072_RS12635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S100072_RS12640	COG0583	DNA-binding transcription factor activity
S100072_RS12645	COG2814	Major facilitator Superfamily
S100072_RS12650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S100072_RS12650	COG2124	cytochrome p450
S100072_RS12655	COG1309	transcriptional regulator
S100072_RS12660	COG2226	methyltransferase
S100072_RS12675	COG2116	formate transmembrane transporter activity
S100072_RS12680	COG5609	conserved protein (DUF2294)
S100072_RS12685	COG3383	formate dehydrogenase (NAD+) activity
S100072_RS12690	COG2427	Protein of unknown function (DUF1641)
S100072_RS12705	COG0626	cystathionine gamma-synthase activity
S100072_RS12710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S100072_RS12735	COG0768	penicillin binding
S100072_RS12750	COG0826	peptidase U32
S100072_RS12755	COG0826	peptidase U32
S100072_RS12760	COG4122	O-methyltransferase activity
S100072_RS12765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S100072_RS12780	COG4472	Bacterial protein of unknown function (DUF965)
S100072_RS12795	COG1126	abc transporter atp-binding protein
S100072_RS12805	COG0765	amino acid transport
S100072_RS12810	COG0765	amino acid transport
S100072_RS12825	COG3881	PFAM PRC-barrel domain
S100072_RS12830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S100072_RS12835	COG0457	Tetratricopeptide repeat
S100072_RS12850	COG1959	2 iron, 2 sulfur cluster binding
S100072_RS12855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S100072_RS12860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S100072_RS12890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S100072_RS12900	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
S100072_RS12900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
S100072_RS12905	COG5416	Lipopolysaccharide assembly protein A domain
S100072_RS12910	COG0490	domain, Protein
S100072_RS12915	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S100072_RS12915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S100072_RS12930	COG2323	membrane
S100072_RS12940	COG1862	Preprotein translocase
S100072_RS12985	COG1388	LysM domain
S100072_RS12995	COG0157	Belongs to the NadC ModD family
S100072_RS13000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
S100072_RS13005	COG1104	cysteine desulfurase activity
S100072_RS13010	COG1827	regulation of RNA biosynthetic process
S100072_RS13015	COG0077	Prephenate dehydratase
S100072_RS13030	COG3290	protein histidine kinase activity
S100072_RS13035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S100072_RS13040	COG2868	ribosomal protein
S100072_RS13050	COG1994	Peptidase M50
S100072_RS13055	COG0739	heme binding
S100072_RS13060	COG2894	cell division
S100072_RS13070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S100072_RS13080	COG1077	Cell shape determining protein MreB Mrl
S100072_RS13105	COG0285	dihydrofolate synthase activity
S100072_RS13110	COG0525	valine-tRNA ligase activity
S100072_RS13120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S100072_RS13125	COG1388	LysM domain
S100072_RS13135	COG0113	porphobilinogen synthase activity
S100072_RS13140	COG1587	Uroporphyrinogen-III synthase
S100072_RS13150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S100072_RS13170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S100072_RS13175	COG1067	ATP-dependent peptidase activity
S100072_RS13175	COG0470	DNA polymerase III
S100072_RS13190	COG0457	Tetratricopeptide repeat
S100072_RS13190	COG1477	protein flavinylation
S100072_RS13205	COG0473	3-isopropylmalate dehydrogenase activity
S100072_RS13220	COG0440	acetolactate synthase activity
S100072_RS13225	COG0028	Belongs to the TPP enzyme family
S100072_RS13255	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
S100072_RS13280	COG0622	Phosphoesterase
S100072_RS13295	COG5401	PFAM Sporulation and spore germination
S100072_RS13305	COG1846	Transcriptional regulator
S100072_RS13310	COG2197	response regulator
S100072_RS13315	COG0824	Thioesterase
S100072_RS13320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S100072_RS13325	COG1053	succinate dehydrogenase
S100072_RS13330	COG2009	succinate dehydrogenase
S100072_RS13335	COG1719	4-vinyl reductase, 4VR
S100072_RS13340	COG0527	aspartate kinase activity
S100072_RS13355	COG3118	belongs to the thioredoxin family
S100072_RS13360	COG3534	alpha-L-arabinofuranosidase
S100072_RS13365	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
S100072_RS13370	COG2086	electron transfer activity
S100072_RS13375	COG1024	Enoyl-CoA hydratase
S100072_RS13380	COG1309	transcriptional regulator
S100072_RS13395	COG3766	membrane
S100072_RS13405	COG1796	DNA polymerase
S100072_RS13405	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S100072_RS13410	COG1286	toxin biosynthetic process
S100072_RS13425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS13425	COG0072	phenylalanine-tRNA ligase activity
S100072_RS13430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S100072_RS13445	COG3835	regulator
S100072_RS13450	COG0277	FAD linked oxidase domain protein
S100072_RS13455	COG0247	lactate metabolic process
S100072_RS13465	COG3534	alpha-L-arabinofuranosidase
S100072_RS13475	COG1175	transmembrane transport
S100072_RS13480	COG1653	transport
S100072_RS13490	COG0647	UMP catabolic process
S100072_RS13495	COG0235	Class ii aldolase
S100072_RS13500	COG1069	ribulokinase activity
S100072_RS13505	COG2160	L-arabinose isomerase activity
S100072_RS13510	COG3507	Belongs to the glycosyl hydrolase 43 family
S100072_RS13515	COG1363	Peptidase, m42
S100072_RS13525	COG3326	Membrane
S100072_RS13540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S100072_RS13545	COG1346	cytolysis
S100072_RS13550	COG1380	Effector of murein hydrolase LrgA
S100072_RS13555	COG3279	Response regulator of the LytR AlgR family
S100072_RS13560	COG3275	phosphorelay sensor kinase activity
S100072_RS13565	COG1011	Hydrolase
S100072_RS13590	COG0398	Pfam SNARE associated Golgi protein
S100072_RS13595	COG1484	DNA-dependent DNA replication
S100072_RS13600	COG3611	Membrane attachment protein
S100072_RS13615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S100072_RS13620	COG1733	regulation of RNA biosynthetic process
S100072_RS13625	COG2814	Major facilitator Superfamily
S100072_RS13630	COG0656	L-ascorbic acid biosynthetic process
S100072_RS13635	COG0237	dephospho-CoA kinase activity
S100072_RS13640	COG1971	Probably functions as a manganese efflux pump
S100072_RS13645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S100072_RS13650	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S100072_RS13650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S100072_RS13655	COG5002	protein histidine kinase activity
S100072_RS13660	COG0745	RESPONSE REGULATOR receiver
S100072_RS13670	COG0538	isocitrate dehydrogenase activity
S100072_RS13675	COG0372	Belongs to the citrate synthase family
S100072_RS13680	COG0457	Tetratricopeptide repeat
S100072_RS13705	COG0628	permease
S100072_RS13710	COG3030	protein affecting phage T7 exclusion by the F plasmid
S100072_RS13715	COG0469	pyruvate kinase activity
S100072_RS13735	COG0281	malic enzyme
S100072_RS13740	COG0587	DNA-directed DNA polymerase activity
S100072_RS13760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S100072_RS13770	COG4109	DRTGG domain
S100072_RS13780	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS13795	COG0521	Mo-molybdopterin cofactor biosynthetic process
S100072_RS13805	COG0827	DNA restriction-modification system
S100072_RS13810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S100072_RS13815	COG3874	Sporulation protein YtfJ
S100072_RS13825	COG1714	RDD family
S100072_RS13830	COG0616	signal peptide processing
S100072_RS13835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S100072_RS13840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S100072_RS13845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S100072_RS13860	COG1104	cysteine desulfurase activity
S100072_RS13865	COG1114	Component of the transport system for branched-chain amino acids
S100072_RS13875	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S100072_RS13880	COG1309	transcriptional regulator
S100072_RS13885	COG1956	GAF domain-containing protein
S100072_RS13905	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS13910	COG4282	regulation of fungal-type cell wall biogenesis
S100072_RS13960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S100072_RS13960	COG1017	nitric oxide dioxygenase activity
S100072_RS13970	COG0693	protein deglycase activity
S100072_RS13990	COG1378	Sugar-specific transcriptional regulator TrmB
S100072_RS14015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S100072_RS14020	COG0454	-acetyltransferase
S100072_RS14025	COG0517	IMP dehydrogenase activity
S100072_RS14030	COG0123	including yeast histone deacetylase and acetoin utilization protein
S100072_RS14035	COG1360	Flagellar Motor Protein
S100072_RS14040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S100072_RS14045	COG1609	Transcriptional regulator
S100072_RS14050	COG1605	Chorismate mutase
S100072_RS14050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S100072_RS14055	COG3118	belongs to the thioredoxin family
S100072_RS14060	COG4980	gas vesicle protein
S100072_RS14065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S100072_RS14075	COG1674	ftsk spoiiie
S100072_RS14080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S100072_RS14090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS14110	COG1363	Peptidase, m42
S100072_RS14115	COG5584	Small secreted protein
S100072_RS14120	COG0281	malic enzyme
S100072_RS14125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S100072_RS14140	COG0510	thiamine kinase activity
S100072_RS14145	COG1597	lipid kinase activity
S100072_RS14155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S100072_RS14160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S100072_RS14165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S100072_RS14170	COG2252	PERMEase
S100072_RS14175	COG4473	ABC transporter
S100072_RS14180	COG1131	(ABC) transporter
S100072_RS14185	COG1349	DNA-binding transcription factor activity
S100072_RS14190	COG1187	pseudouridine synthase activity
S100072_RS14195	COG2244	polysaccharide biosynthetic process
S100072_RS14200	COG2081	HI0933 family
S100072_RS14220	COG1609	Transcriptional regulator
S100072_RS14225	COG1653	transport
S100072_RS14230	COG1175	transmembrane transport
S100072_RS14235	COG0395	ABC-type sugar transport system, permease component
S100072_RS14240	COG1486	melibiose metabolic process
S100072_RS14250	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S100072_RS14265	COG1366	Belongs to the anti-sigma-factor antagonist family
S100072_RS14265	COG2202	Pas domain
S100072_RS14270	COG2814	Major facilitator Superfamily
S100072_RS14275	COG5522	Integral membrane protein (intg_mem_TP0381)
S100072_RS14280	COG0577	efflux transmembrane transporter activity
S100072_RS14285	COG1136	(ABC) transporter
S100072_RS14290	COG2205	protein histidine kinase activity
S100072_RS14295	COG0745	RESPONSE REGULATOR receiver
S100072_RS14300	COG0577	efflux transmembrane transporter activity
S100072_RS14305	COG1136	(ABC) transporter
S100072_RS14325	COG1131	(ABC) transporter
S100072_RS14330	COG1725	Transcriptional regulator
S100072_RS14340	COG0640	Transcriptional regulator
S100072_RS14345	COG0477	Major facilitator Superfamily
S100072_RS14350	COG1242	4 iron, 4 sulfur cluster binding
S100072_RS14355	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S100072_RS14365	COG0584	glycerophosphoryl diester phosphodiesterase
S100072_RS14375	COG2267	carboxylic ester hydrolase activity
S100072_RS14385	COG1113	amino acid transport
S100072_RS14410	COG1506	peptidase
S100072_RS14415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S100072_RS14420	COG1116	anion transmembrane transporter activity
S100072_RS14425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S100072_RS14430	COG0494	nUDIX hydrolase
S100072_RS14435	COG4824	toxin secretion phage lysis holin
S100072_RS14440	COG0783	Belongs to the Dps family
S100072_RS14465	COG0288	reversible hydration of carbon dioxide
S100072_RS14475	COG1271	oxidase subunit
S100072_RS14480	COG1294	oxidase, subunit
S100072_RS14490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S100072_RS14495	COG1321	iron dependent repressor
S100072_RS14495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S100072_RS14505	COG0803	Belongs to the bacterial solute-binding protein 9 family
S100072_RS14510	COG4948	Mandelate Racemase Muconate Lactonizing
S100072_RS14520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S100072_RS14525	COG0596	Alpha beta hydrolase
S100072_RS14535	COG1169	isochorismate synthase
S100072_RS14540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S100072_RS14545	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S100072_RS14670	COG3859	Proton-coupled thiamine transporter YuaJ
S100072_RS14675	COG2268	Band 7 protein
S100072_RS14680	COG1585	Membrane protein implicated in regulation of membrane protease activity
S100072_RS14685	COG2318	DinB family
S100072_RS14695	COG1454	alcohol dehydrogenase
S100072_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS14705	COG1510	regulation of RNA biosynthetic process
S100072_RS14715	COG0569	domain protein
S100072_RS14720	COG1705	Flagellar rod assembly protein muramidase FlgJ
S100072_RS14725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S100072_RS14725	COG1017	nitric oxide dioxygenase activity
S100072_RS14750	COG5444	nuclease activity
S100072_RS14765	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
S100072_RS14780	COG0628	permease
S100072_RS14785	COG0673	inositol 2-dehydrogenase activity
S100072_RS14790	COG0693	protein deglycase activity
S100072_RS14795	COG0840	transmembrane signaling receptor activity
S100072_RS14800	COG0840	transmembrane signaling receptor activity
S100072_RS14805	COG0840	transmembrane signaling receptor activity
S100072_RS14810	COG0840	transmembrane signaling receptor activity
S100072_RS14825	COG2070	2-Nitropropane dioxygenase
S100072_RS14830	COG0432	Pfam Uncharacterised protein family UPF0047
S100072_RS14835	COG0366	Alpha amylase catalytic
S100072_RS14840	COG1253	flavin adenine dinucleotide binding
S100072_RS14845	COG2738	Putative neutral zinc metallopeptidase
S100072_RS14860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S100072_RS14890	COG1335	isochorismatase
S100072_RS14900	COG1979	alcohol dehydrogenase
S100072_RS14905	COG2155	Conserved Protein
S100072_RS14910	COG1098	S1 RNA binding domain
S100072_RS14915	COG0436	Aminotransferase
S100072_RS14920	COG1522	sequence-specific DNA binding
S100072_RS14925	COG2267	carboxylic ester hydrolase activity
S100072_RS14935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S100072_RS14940	COG2205	protein histidine kinase activity
S100072_RS14950	COG5018	Exonuclease
S100072_RS14955	COG2814	Major facilitator Superfamily
S100072_RS14960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S100072_RS14965	COG3011	Protein conserved in bacteria
S100072_RS14975	COG3290	protein histidine kinase activity
S100072_RS14980	COG4565	transcriptional regulatory protein
S100072_RS14990	COG3845	ABC transporter
S100072_RS14995	COG4603	Belongs to the binding-protein-dependent transport system permease family
S100072_RS15000	COG1079	Belongs to the binding-protein-dependent transport system permease family
S100072_RS15015	COG2111	Na H antiporter
S100072_RS15020	COG1006	Multisubunit Na H antiporter MnhC subunit
S100072_RS15030	COG1863	multisubunit Na H antiporter MnhE subunit
S100072_RS15035	COG2212	antiporter activity
S100072_RS15040	COG1320	monovalent cation:proton antiporter activity
S100072_RS15045	COG2050	protein possibly involved in aromatic compounds catabolism
S100072_RS15050	COG2197	response regulator
S100072_RS15065	COG0142	geranyltranstransferase activity
S100072_RS15085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S100072_RS15090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S100072_RS15095	COG1335	isochorismatase
S100072_RS15100	COG5506	Protein of unknown function (DUF1694)
S100072_RS15115	COG0628	permease
S100072_RS15125	COG1418	mRNA catabolic process
S100072_RS15130	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS15140	COG1511	domain protein
S100072_RS15145	COG0433	COG0433 Predicted ATPase
S100072_RS15145	COG1674	ftsk spoiiie
S100072_RS15150	COG1674	ftsk spoiiie
S100072_RS15150	COG0433	COG0433 Predicted ATPase
S100072_RS15160	COG5417	Belongs to the EsaB family
S100072_RS15165	COG4842	Belongs to the WXG100 family
S100072_RS15170	COG2508	Transcriptional regulator
S100072_RS15170	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S100072_RS15175	COG0686	Belongs to the AlaDH PNT family
S100072_RS15180	COG5634	Uncharacterized conserved protein (DUF2278)
S100072_RS15185	COG3251	PFAM MbtH domain protein
S100072_RS15190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S100072_RS15195	COG1535	isochorismatase
S100072_RS15195	COG3433	isochorismatase activity
S100072_RS15200	COG1021	2,3-dihydroxybenzoate-AMP ligase
S100072_RS15205	COG1169	isochorismate synthase
S100072_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS15215	COG2819	hydrolase of the alpha beta superfamily
S100072_RS15220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S100072_RS15225	COG1268	BioY protein
S100072_RS15230	COG2056	Na+-H+ antiporter family
S100072_RS15240	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
S100072_RS15245	COG3584	3D domain protein
S100072_RS15260	COG1252	NADH dehydrogenase
S100072_RS15290	COG1131	(ABC) transporter
S100072_RS15310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S100072_RS15315	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S100072_RS15320	COG0316	Belongs to the HesB IscA family
S100072_RS15330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S100072_RS15340	COG1252	NADH dehydrogenase
S100072_RS15345	COG4837	Protein of unknown function (DUF1462)
S100072_RS15350	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
S100072_RS15355	COG0823	Involved in the tonB-independent uptake of proteins
S100072_RS15355	COG1506	peptidase
S100072_RS15355	COG4946	Tricorn protease homolog
S100072_RS15365	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S100072_RS15370	COG0460	homoserine dehydrogenase
S100072_RS15375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S100072_RS15380	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S100072_RS15385	COG0647	UMP catabolic process
S100072_RS15390	COG2445	Protein of unknown function DUF86
S100072_RS15395	COG4470	Protein conserved in bacteria
S100072_RS15410	COG0739	heme binding
S100072_RS15420	COG0737	Belongs to the 5'-nucleotidase family
S100072_RS15425	COG0730	response to heat
S100072_RS15430	COG1801	Protein of unknown function DUF72
S100072_RS15445	COG2508	Transcriptional regulator
S100072_RS15460	COG2814	Major facilitator Superfamily
S100072_RS15465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
S100072_RS15470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S100072_RS15475	COG2356	endonuclease I
S100072_RS15485	COG2188	Transcriptional regulator
S100072_RS15495	COG0395	ABC-type sugar transport system, permease component
S100072_RS15500	COG1175	transmembrane transport
S100072_RS15515	COG0789	Transcriptional regulator
S100072_RS15540	COG0322	excinuclease ABC activity
S100072_RS15545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S100072_RS15550	COG2226	methyltransferase
S100072_RS15565	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS15570	COG5632	N-Acetylmuramoyl-L-alanine amidase
S100072_RS15570	COG1388	LysM domain
S100072_RS15570	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS15600	COG5434	Belongs to the glycosyl hydrolase 28 family
S100072_RS15605	COG1705	Flagellar rod assembly protein muramidase FlgJ
S100072_RS15615	COG3953	SLT domain
S100072_RS15615	COG5412	phage tail tape measure protein
S100072_RS15725	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S100072_RS15725	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S100072_RS15780	COG1396	sequence-specific DNA binding
S100072_RS15790	COG4974	Belongs to the 'phage' integrase family
S100072_RS15795	COG0719	Fe-S assembly protein
S100072_RS15800	COG0822	iron-sulfur transferase activity
S100072_RS15805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S100072_RS15810	COG0719	Fe-S assembly protein
S100072_RS15815	COG0396	ATPase activity
S100072_RS15825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S100072_RS15830	COG1464	Belongs to the NlpA lipoprotein family
S100072_RS15835	COG2011	ABC-type metal ion transport system permease component
S100072_RS15840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
S100072_RS15850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S100072_RS15855	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S100072_RS15870	COG1393	Belongs to the ArsC family
S100072_RS15875	COG1960	acyl-CoA dehydrogenase activity
S100072_RS15885	COG1250	3-hydroxyacyl-CoA dehydrogenase
S100072_RS15885	COG1024	Enoyl-CoA hydratase
S100072_RS15905	COG5577	PFAM Coat F domain
S100072_RS15910	COG1846	Transcriptional regulator
S100072_RS15915	COG0477	Major facilitator Superfamily
S100072_RS15945	COG1120	ATPase activity
S100072_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS15965	COG0783	Belongs to the Dps family
S100072_RS15970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S100072_RS15985	COG2770	Histidine kinase
S100072_RS15985	COG2205	protein histidine kinase activity
S100072_RS15995	COG1309	transcriptional regulator
S100072_RS16000	COG0114	fumarate hydratase activity
S100072_RS16010	COG0697	spore germination
S100072_RS16015	COG0814	amino acid
S100072_RS16025	COG2197	response regulator
S100072_RS16030	COG4585	Histidine kinase
S100072_RS16035	COG4758	membrane
S100072_RS16040	COG3595	metallopeptidase activity
S100072_RS16045	COG1842	Phage shock protein A
S100072_RS16050	COG4758	membrane
S100072_RS16055	COG2814	Major facilitator Superfamily
S100072_RS16060	COG2096	Adenosyltransferase
S100072_RS16065	COG1120	ATPase activity
S100072_RS16070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S100072_RS16080	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS16085	COG3386	PFAM SMP-30 Gluconolaconase
S100072_RS16095	COG0745	RESPONSE REGULATOR receiver
S100072_RS16105	COG1191	sigma factor activity
S100072_RS16115	COG2140	Oxalate decarboxylase
S100072_RS16125	COG1120	ATPase activity
S100072_RS16130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS16140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S100072_RS16145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S100072_RS16150	COG0531	amino acid
S100072_RS16165	COG1988	membrane-bound metal-dependent
S100072_RS16175	COG1910	domain protein
S100072_RS16180	COG0725	ABC transporter, periplasmic molybdate-binding protein
S100072_RS16185	COG4149	molybdate abc transporter
S100072_RS16190	COG2197	response regulator
S100072_RS16195	COG3850	Histidine kinase
S100072_RS16200	COG1131	(ABC) transporter
S100072_RS16210	COG0842	Transport permease protein
S100072_RS16215	COG0656	L-ascorbic acid biosynthetic process
S100072_RS16240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S100072_RS16245	COG3973	AAA domain
S100072_RS16250	COG2860	membrane
S100072_RS16260	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S100072_RS16265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S100072_RS16270	COG2217	Heavy metal translocating P-type atpase
S100072_RS16280	COG2608	mercury ion transmembrane transporter activity
S100072_RS16285	COG1937	Protein conserved in bacteria
S100072_RS16290	COG0673	inositol 2-dehydrogenase activity
S100072_RS16300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S100072_RS16305	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
S100072_RS16310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S100072_RS16315	COG1126	abc transporter atp-binding protein
S100072_RS16320	COG0765	amino acid transport
S100072_RS16325	COG0765	amino acid transport
S100072_RS16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S100072_RS16335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S100072_RS16340	COG0454	-acetyltransferase
S100072_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS16355	COG2732	(Barnase) inhibitor
S100072_RS16365	COG2732	(Barnase) inhibitor
S100072_RS16380	COG0557	exoribonuclease II activity
S100072_RS16385	COG1647	Serine aminopeptidase, S33
S100072_RS16390	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S100072_RS16395	COG1476	TRANSCRIPTIONal
S100072_RS16400	COG1396	sequence-specific DNA binding
S100072_RS16405	COG1396	sequence-specific DNA binding
S100072_RS16410	COG1733	regulation of RNA biosynthetic process
S100072_RS16435	COG1131	(ABC) transporter
S100072_RS16440	COG1174	glycine betaine transport
S100072_RS16445	COG1732	Glycine betaine
S100072_RS16450	COG1174	glycine betaine transport
S100072_RS16455	COG0517	IMP dehydrogenase activity
S100072_RS16455	COG1125	glycine betaine transport
S100072_RS16460	COG1510	regulation of RNA biosynthetic process
S100072_RS16465	COG1174	glycine betaine transport
S100072_RS16470	COG1732	Glycine betaine
S100072_RS16475	COG1174	glycine betaine transport
S100072_RS16480	COG0517	IMP dehydrogenase activity
S100072_RS16480	COG1125	glycine betaine transport
S100072_RS16485	COG1510	regulation of RNA biosynthetic process
S100072_RS16490	COG2095	MarC family integral membrane protein
S100072_RS16500	COG3064	Membrane
S100072_RS16505	COG4640	response to antibiotic
S100072_RS16510	COG0456	acetyltransferase
S100072_RS16530	COG0126	phosphoglycerate kinase activity
S100072_RS16540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S100072_RS16545	COG2390	Transcriptional regulator
S100072_RS16550	COG2814	Major facilitator Superfamily
S100072_RS16555	COG1609	Transcriptional regulator
S100072_RS16570	COG0583	DNA-binding transcription factor activity
S100072_RS16575	COG0697	spore germination
S100072_RS16580	COG1113	amino acid transport
S100072_RS16600	COG0561	phosphatase activity
S100072_RS16605	COG1737	Transcriptional regulator
S100072_RS16610	COG1070	Carbohydrate kinase
S100072_RS16635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S100072_RS16640	COG2186	Transcriptional regulator
S100072_RS16645	COG1620	l-lactate permease
S100072_RS16650	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S100072_RS16660	COG5039	Polysaccharide pyruvyl transferase
S100072_RS16665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S100072_RS16670	COG0110	maltose O-acetyltransferase activity
S100072_RS16675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S100072_RS16680	COG2244	polysaccharide biosynthetic process
S100072_RS16685	COG1216	Glycosyl transferase, family 2
S100072_RS16690	COG5039	Polysaccharide pyruvyl transferase
S100072_RS16695	COG1216	Glycosyl transferase, family 2
S100072_RS16705	COG0438	transferase activity, transferring glycosyl groups
S100072_RS16710	COG1215	transferase activity, transferring glycosyl groups
S100072_RS16715	COG0438	transferase activity, transferring glycosyl groups
S100072_RS16725	COG0489	protein tyrosine kinase activity
S100072_RS16730	COG3944	biosynthesis protein
S100072_RS16735	COG1396	sequence-specific DNA binding
S100072_RS16740	COG2272	Belongs to the type-B carboxylesterase lipase family
S100072_RS16750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S100072_RS16755	COG2364	Membrane
S100072_RS16760	COG0456	acetyltransferase
S100072_RS16765	COG3479	Phenolic acid decarboxylase
S100072_RS16805	COG2223	nitrite transmembrane transporter activity
S100072_RS16810	COG1609	Transcriptional regulator
S100072_RS16820	COG0583	DNA-binding transcription factor activity
S100072_RS16825	COG2828	Protein conserved in bacteria
S100072_RS16830	COG0477	Major facilitator Superfamily
S100072_RS16830	COG2814	Major facilitator Superfamily
S100072_RS16835	COG1611	Belongs to the LOG family
S100072_RS16840	COG1694	Mazg nucleotide pyrophosphohydrolase
S100072_RS16845	COG0659	secondary active sulfate transmembrane transporter activity
S100072_RS16850	COG0288	reversible hydration of carbon dioxide
S100072_RS16865	COG4290	ribonuclease
S100072_RS16870	COG2162	N-hydroxyarylamine O-acetyltransferase activity
S100072_RS16875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS16885	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S100072_RS16900	COG0492	ferredoxin-NADP+ reductase activity
S100072_RS16905	COG0791	NLP P60 protein
S100072_RS16905	COG3883	PFAM NLP P60 protein
S100072_RS16910	COG0457	Tetratricopeptide repeat
S100072_RS16915	COG5002	protein histidine kinase activity
S100072_RS16920	COG0745	RESPONSE REGULATOR receiver
S100072_RS16925	COG1132	(ABC) transporter
S100072_RS16930	COG0140	phosphoribosyl-ATP diphosphatase activity
S100072_RS16930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S100072_RS16955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S100072_RS16970	COG4990	cell redox homeostasis
S100072_RS16975	COG0110	maltose O-acetyltransferase activity
S100072_RS17005	COG2188	Transcriptional regulator
S100072_RS17010	COG1309	transcriptional regulator
S100072_RS17015	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
S100072_RS17020	COG1950	PFAM Membrane protein of
S100072_RS17025	COG1983	PspC domain protein
S100072_RS17030	COG3595	metallopeptidase activity
S100072_RS17045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S100072_RS17055	COG4897	Protein conserved in bacteria
S100072_RS17060	COG3848	Pyruvate phosphate dikinase
S100072_RS17060	COG0574	Belongs to the PEP-utilizing enzyme family
S100072_RS17065	COG1309	transcriptional regulator
S100072_RS17070	COG2814	Major facilitator Superfamily
S100072_RS17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S100072_RS17095	COG0793	Belongs to the peptidase S41A family
S100072_RS17095	COG3409	Peptidoglycan-binding domain 1 protein
S100072_RS17100	COG3420	alginic acid biosynthetic process
S100072_RS17110	COG2884	Cell division ATP-binding protein ftsE
S100072_RS17115	COG2010	Cytochrome c
S100072_RS17120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS17135	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S100072_RS17150	COG1516	flagellar protein fliS
S100072_RS17155	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S100072_RS17160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S100072_RS17180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S100072_RS17185	COG4786	Flagellar basal body rod
S100072_RS17185	COG1256	bacterial-type flagellum assembly
S100072_RS17190	COG3418	PFAM FlgN family protein
S100072_RS17195	COG2747	anti-sigma28 factor FlgM
S100072_RS17205	COG1040	competence protein
S100072_RS17215	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S100072_RS17220	COG1307	EDD domain protein, DegV family
S100072_RS17225	COG2197	response regulator
S100072_RS17230	COG4585	Histidine kinase
S100072_RS17235	COG1739	Uncharacterized protein family UPF0029
S100072_RS17240	COG1316	TRANSCRIPTIONal
S100072_RS17245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S100072_RS17250	COG0438	transferase activity, transferring glycosyl groups
S100072_RS17255	COG1215	transferase activity, transferring glycosyl groups
S100072_RS17260	COG3206	protein involved in exopolysaccharide biosynthesis
S100072_RS17270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S100072_RS17275	COG0297	glycogen (starch) synthase activity
S100072_RS17275	COG0438	transferase activity, transferring glycosyl groups
S100072_RS17280	COG2244	polysaccharide biosynthetic process
S100072_RS17290	COG0860	N-Acetylmuramoyl-L-alanine amidase
S100072_RS17290	COG2247	cell wall binding repeat
S100072_RS17295	COG2247	cell wall binding repeat
S100072_RS17295	COG2385	sporulation resulting in formation of a cellular spore
S100072_RS17305	COG1316	TRANSCRIPTIONal
S100072_RS17310	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S100072_RS17315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S100072_RS17320	COG1134	teichoic acid transport
S100072_RS17325	COG1682	transport, permease protein
S100072_RS17330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S100072_RS17335	COG0438	transferase activity, transferring glycosyl groups
S100072_RS17340	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S100072_RS17345	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S100072_RS17350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S100072_RS17355	COG4193	domain, Protein
S100072_RS17360	COG1482	cell wall glycoprotein biosynthetic process
S100072_RS17365	COG0697	spore germination
S100072_RS17380	COG1215	transferase activity, transferring glycosyl groups
S100072_RS17385	COG2814	Major facilitator Superfamily
S100072_RS17390	COG1316	TRANSCRIPTIONal
S100072_RS17395	COG0561	phosphatase activity
S100072_RS17400	COG2433	Pfam Transposase IS66
S100072_RS17405	COG0791	NLP P60 protein
S100072_RS17415	COG2843	Capsule synthesis protein
S100072_RS17425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S100072_RS17435	COG0697	spore germination
S100072_RS17440	COG0814	amino acid
S100072_RS17465	COG1129	ABC transporter
S100072_RS17470	COG1172	Belongs to the binding-protein-dependent transport system permease family
S100072_RS17475	COG1879	ABC-type sugar transport system periplasmic component
S100072_RS17480	COG3103	Sh3 type 3 domain protein
S100072_RS17485	COG2249	NAD(P)H dehydrogenase (quinone) activity
S100072_RS17490	COG3527	Alpha-acetolactate decarboxylase
S100072_RS17495	COG0028	Belongs to the TPP enzyme family
S100072_RS17500	COG0583	DNA-binding transcription factor activity
S100072_RS17505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S100072_RS17520	COG5337	Spore coat protein CotH
S100072_RS17530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S100072_RS17540	COG0405	Gamma-glutamyltransferase
S100072_RS17545	COG1522	sequence-specific DNA binding
S100072_RS17550	COG2059	Chromate
S100072_RS17555	COG2059	Chromate
S100072_RS17565	COG0655	NAD(P)H dehydrogenase (quinone) activity
S100072_RS17570	COG0583	DNA-binding transcription factor activity
S100072_RS17615	COG3878	Protein conserved in bacteria
S100072_RS17620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S100072_RS17625	COG4464	protein tyrosine phosphatase activity
S100072_RS17630	COG0489	protein tyrosine kinase activity
S100072_RS17635	COG3944	biosynthesis protein
S100072_RS17650	COG4715	Zinc finger, swim domain protein
S100072_RS17655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S100072_RS17660	COG0561	phosphatase activity
S100072_RS17665	COG1349	DNA-binding transcription factor activity
S100072_RS17670	COG0629	single-stranded DNA binding
S100072_RS17695	COG0457	Tetratricopeptide repeat
S100072_RS17700	COG4786	Flagellar basal body rod
S100072_RS17705	COG4786	Flagellar basal body rod
S100072_RS17710	COG1077	Cell shape determining protein MreB Mrl
S100072_RS17720	COG1846	Transcriptional regulator
S100072_RS17725	COG2814	Major facilitator Superfamily
S100072_RS17730	COG1953	Uracil, thiamine, allantoin
S100072_RS17735	COG0477	Major facilitator Superfamily
S100072_RS17740	COG1335	isochorismatase
S100072_RS17745	COG0004	ammonium transporteR
S100072_RS17750	COG0347	Belongs to the P(II) protein family
S100072_RS17755	COG0772	Belongs to the SEDS family
S100072_RS17760	COG0671	phosphoesterase, PA-phosphatase related
S100072_RS17770	COG0739	heme binding
S100072_RS17775	COG1247	-acetyltransferase
S100072_RS17800	COG0726	polysaccharide deacetylase
S100072_RS17810	COG1959	2 iron, 2 sulfur cluster binding
S100072_RS17825	COG0831	urea catabolic process
S100072_RS17835	COG1994	Peptidase M50
S100072_RS17840	COG0457	Tetratricopeptide repeat
S100072_RS17850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S100072_RS17855	COG2304	oxidoreductase activity
S100072_RS17860	COG2304	oxidoreductase activity
S100072_RS17865	COG2385	sporulation resulting in formation of a cellular spore
S100072_RS17870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S100072_RS17880	COG4836	Membrane
S100072_RS17950	COG0698	ribose 5-phosphate isomerase
S100072_RS17955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S100072_RS17965	COG0009	L-threonylcarbamoyladenylate synthase
S100072_RS17970	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S100072_RS17990	COG2890	protein-(glutamine-N5) methyltransferase activity
S100072_RS17995	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S100072_RS18000	COG0346	lactoylglutathione lyase activity
S100072_RS18005	COG0789	Transcriptional regulator
S100072_RS18010	COG0679	Auxin Efflux Carrier
S100072_RS18015	COG0281	malic enzyme
S100072_RS18030	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S100072_RS18035	COG1494	fructose-1,6-bisphosphatase
S100072_RS18040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S100072_RS18050	COG0191	fructose-bisphosphate aldolase activity
S100072_RS18055	COG2204	response regulator
S100072_RS18060	COG4821	SIS domain
S100072_RS18075	COG0247	lactate metabolic process
S100072_RS18075	COG2181	nitrate reductase activity
S100072_RS18080	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S100072_RS18095	COG1132	(ABC) transporter
S100072_RS18100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S100072_RS18110	COG2181	nitrate reductase activity
S100072_RS18115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S100072_RS18120	COG1140	nitrate reductase beta subunit
S100072_RS18130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S100072_RS18140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S100072_RS18145	COG2223	nitrite transmembrane transporter activity
S100072_RS18155	COG4506	Protein conserved in bacteria
S100072_RS18160	COG0457	Tetratricopeptide repeat
S100072_RS18170	COG0010	Belongs to the arginase family
S100072_RS18175	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S100072_RS18180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S100072_RS18195	COG1994	Peptidase M50
S100072_RS18200	COG1942	4-Oxalocrotonate Tautomerase
S100072_RS18205	COG1846	Transcriptional regulator
S100072_RS18215	COG0531	amino acid
S100072_RS18220	COG3465	dGTPase activity
S100072_RS18225	COG1078	dGTPase activity
S100072_RS18240	COG1695	Transcriptional regulator
S100072_RS18250	COG1131	(ABC) transporter
S100072_RS18285	COG0583	DNA-binding transcription factor activity
S100072_RS18290	COG2855	membrane
S100072_RS18295	COG0280	phosphate acetyltransferase
S100072_RS18305	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS18310	COG0436	Aminotransferase
S100072_RS18345	COG2814	Major facilitator Superfamily
S100072_RS18350	COG0833	amino acid
S100072_RS18355	COG4187	Peptidase family M20/M25/M40
S100072_RS18360	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS18365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S100072_RS18370	COG2205	protein histidine kinase activity
S100072_RS18375	COG0745	RESPONSE REGULATOR receiver
S100072_RS18390	COG1131	(ABC) transporter
S100072_RS18395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S100072_RS18400	COG1091	dTDP-4-dehydrorhamnose reductase activity
S100072_RS18405	COG1088	dTDP-glucose 4,6-dehydratase activity
S100072_RS18410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S100072_RS18415	COG3980	spore coat polysaccharide biosynthesis protein
S100072_RS18420	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
S100072_RS18425	COG2089	acid synthase
S100072_RS18430	COG0456	acetyltransferase
S100072_RS18435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S100072_RS18440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S100072_RS18445	COG0463	Glycosyl transferase, family 2
S100072_RS18455	COG2363	Small membrane protein
S100072_RS18460	COG2233	PERMEase
S100072_RS18475	COG1216	Glycosyl transferase, family 2
S100072_RS18490	COG1695	Transcriptional regulator
S100072_RS18495	COG0351	phosphomethylpyrimidine kinase
S100072_RS18505	COG1621	beta-fructofuranosidase activity
S100072_RS18510	COG1263	PTS System
S100072_RS18510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S100072_RS18515	COG3711	transcriptional antiterminator
S100072_RS18525	COG1404	Belongs to the peptidase S8 family
S100072_RS18530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S100072_RS18535	COG0778	Nitroreductase
S100072_RS18540	COG0772	Belongs to the SEDS family
S100072_RS18550	COG0454	-acetyltransferase
S100072_RS18570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S100072_RS18575	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S100072_RS18585	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S100072_RS18595	COG2246	polysaccharide biosynthetic process
S100072_RS18600	COG1309	transcriptional regulator
S100072_RS18620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S100072_RS18630	COG2822	iron ion transport
S100072_RS18645	COG0583	DNA-binding transcription factor activity
S100072_RS18655	COG1346	cytolysis
S100072_RS18660	COG4895	conserved protein (DUF2196)
S100072_RS18670	COG5504	Zn-dependent protease
S100072_RS18680	COG0346	lactoylglutathione lyase activity
S100072_RS18685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S100072_RS18690	COG1404	Belongs to the peptidase S8 family
S100072_RS18695	COG1442	glycosyl transferase family 8
S100072_RS18700	COG2357	RelA SpoT domain protein
S100072_RS18705	COG1575	Belongs to the MenA family. Type 1 subfamily
S100072_RS18730	COG1696	Membrane protein involved in D-alanine export
S100072_RS18740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
S100072_RS18745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S100072_RS18750	COG1486	melibiose metabolic process
S100072_RS18755	COG1447	Phosphotransferase system cellobiose-specific component IIA
S100072_RS18760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S100072_RS18765	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S100072_RS18770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S100072_RS18770	COG3711	transcriptional antiterminator
S100072_RS18785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS18790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S100072_RS18800	COG0640	Transcriptional regulator
S100072_RS18810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S100072_RS18815	COG1447	Phosphotransferase system cellobiose-specific component IIA
S100072_RS18820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S100072_RS18830	COG1940	carbohydrate kinase activity
S100072_RS18835	COG1482	cell wall glycoprotein biosynthetic process
S100072_RS18845	COG0753	catalase activity
S100072_RS18850	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S100072_RS18855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S100072_RS18860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S100072_RS18865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S100072_RS18870	COG4988	ABC transporter
S100072_RS18875	COG1294	oxidase, subunit
S100072_RS18880	COG1271	oxidase subunit
S100072_RS18885	COG3493	citrate carrier protein
S100072_RS18890	COG0726	polysaccharide deacetylase
S100072_RS18895	COG3842	ATPase activity
S100072_RS18905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS18915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S100072_RS18925	COG4894	glucomannan catabolic process
S100072_RS18930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S100072_RS18935	COG0500	methyltransferase
S100072_RS18940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S100072_RS18955	COG0753	catalase activity
S100072_RS18955	COG0693	protein deglycase activity
S100072_RS18960	COG2851	Citrate transporter
S100072_RS18965	COG2273	Hydrolase Family 16
S100072_RS18975	COG2270	Major facilitator Superfamily
S100072_RS18980	COG0513	Belongs to the DEAD box helicase family
S100072_RS19080	COG0697	spore germination
S100072_RS19085	COG0589	response to stress
S100072_RS19095	COG0494	nUDIX hydrolase
S100072_RS19100	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
S100072_RS19105	COG3507	Belongs to the glycosyl hydrolase 43 family
S100072_RS19130	COG0010	Belongs to the arginase family
S100072_RS19140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S100072_RS19145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S100072_RS19155	COG2390	Transcriptional regulator
S100072_RS19185	COG1131	(ABC) transporter
S100072_RS19195	COG0561	phosphatase activity
S100072_RS19225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S100072_RS19230	COG5294	Protein conserved in bacteria
S100072_RS19235	COG0577	efflux transmembrane transporter activity
S100072_RS19240	COG1136	(ABC) transporter
S100072_RS19245	COG2205	protein histidine kinase activity
S100072_RS19265	COG1082	Xylose isomerase domain protein TIM barrel
S100072_RS19275	COG2814	Major facilitator Superfamily
S100072_RS19305	COG1349	DNA-binding transcription factor activity
S100072_RS19310	COG0667	Aldo Keto reductase
S100072_RS19315	COG2814	Major facilitator Superfamily
S100072_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
S100072_RS19335	COG2197	response regulator
S100072_RS19340	COG4585	Histidine kinase
S100072_RS19345	COG3239	Fatty acid desaturase
S100072_RS19350	COG1309	transcriptional regulator
S100072_RS19360	COG1476	TRANSCRIPTIONal
S100072_RS19390	COG1012	belongs to the aldehyde dehydrogenase family
S100072_RS19405	COG0640	Transcriptional regulator
S100072_RS19410	COG2814	Major facilitator Superfamily
S100072_RS19415	COG1714	RDD family
S100072_RS19425	COG0450	alkyl hydroperoxide reductase
S100072_RS19430	COG3634	alkyl hydroperoxide reductase activity
S100072_RS19435	COG3177	Filamentation induced by cAMP protein fic
S100072_RS19440	COG1113	amino acid transport
S100072_RS19450	COG2080	2 iron, 2 sulfur cluster binding
S100072_RS19465	COG2068	MobA-Related Protein
S100072_RS19470	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
S100072_RS19510	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S100072_RS19515	COG0667	Aldo Keto reductase
S100072_RS19520	COG0456	acetyltransferase
S100072_RS19525	COG0457	Tetratricopeptide repeat
S100072_RS19530	COG0010	Belongs to the arginase family
S100072_RS19535	COG0833	amino acid
S100072_RS19540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S100072_RS19545	COG5658	integral membrane protein
S100072_RS19550	COG0640	Transcriptional regulator
S100072_RS19555	COG3829	transcription factor binding
S100072_RS19565	COG0488	(ABC) transporter
S100072_RS19580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S100072_RS19585	COG3850	Histidine kinase
S100072_RS19585	COG5002	protein histidine kinase activity
S100072_RS19590	COG0745	RESPONSE REGULATOR receiver
S100072_RS19600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S100072_RS19605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S100072_RS19610	COG4853	Protein conserved in bacteria
S100072_RS19615	COG4863	YycH protein
S100072_RS19620	COG5002	protein histidine kinase activity
S100072_RS19625	COG0745	RESPONSE REGULATOR receiver
S100072_RS19660	COG0346	lactoylglutathione lyase activity
S100072_RS19665	COG0305	Participates in initiation and elongation during chromosome replication
S100072_RS19680	COG3093	addiction module antidote protein HigA
S100072_RS19685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S100072_RS19690	COG0297	glycogen (starch) synthase activity
S100072_RS19705	COG0438	transferase activity, transferring glycosyl groups
S100072_RS19715	COG2112	serine threonine protein kinase
S100072_RS19725	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S100072_RS19730	COG4241	membrane
S100072_RS19740	COG5577	PFAM Coat F domain
S100072_RS19745	COG1733	regulation of RNA biosynthetic process
S100072_RS19755	COG0697	spore germination
S100072_RS19760	COG1621	beta-fructofuranosidase activity
S100072_RS19765	COG1621	beta-fructofuranosidase activity
S100072_RS19770	COG1802	Transcriptional regulator
S100072_RS19775	COG2318	DinB family
S100072_RS19795	COG0778	Nitroreductase
S100072_RS19800	COG1846	Transcriptional regulator
S100072_RS19805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S100072_RS19810	COG1846	Transcriptional regulator
S100072_RS19815	COG2153	protein acetylation
S100072_RS19820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S100072_RS19825	COG0697	spore germination
S100072_RS19835	COG0789	Transcriptional regulator
S100072_RS19835	COG4978	Transcriptional regulator
S100072_RS19840	COG1811	Na channel or pump
S100072_RS19845	COG1331	Highly conserved protein containing a thioredoxin domain
S100072_RS19850	COG1331	Highly conserved protein containing a thioredoxin domain
S100072_RS19855	COG1266	CAAX protease self-immunity
S100072_RS19860	COG0477	Major facilitator Superfamily
S100072_RS19860	COG2814	Major facilitator Superfamily
S100072_RS19865	COG0346	lactoylglutathione lyase activity
S100072_RS19870	COG1609	Transcriptional regulator
S100072_RS19875	COG0708	Exodeoxyribonuclease III
S100072_RS19880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S100072_RS19885	COG2169	Transcriptional regulator
S100072_RS19895	COG0629	single-stranded DNA binding
S100072_RS19905	COG0012	GTP binding
S100072_RS19915	COG4481	Protein conserved in bacteria
S100072_RS19920	COG3949	Membrane
S100072_RS19935	COG1475	DNA binding
S100072_RS19940	COG1192	Involved in chromosome partitioning
S100072_RS19965	COG1847	R3H domain protein
S100072_RS19970	COG0706	membrane insertase activity