locus-tag	class	description
S101413_RS00010	COG0592	DNA-directed DNA polymerase activity
S101413_RS00015	COG2501	S4 domain
S101413_RS00030	COG0187	DNA topoisomerase II activity
S101413_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
S101413_RS00070	COG0517	IMP dehydrogenase activity
S101413_RS00070	COG0516	GMP reductase activity
S101413_RS00075	COG1686	Belongs to the peptidase S11 family
S101413_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
S101413_RS00110	COG1428	Deoxynucleoside kinase
S101413_RS00115	COG1388	LysM domain
S101413_RS00115	COG3858	chitin binding
S101413_RS00120	COG1335	isochorismatase
S101413_RS00125	COG0590	tRNA wobble adenosine to inosine editing
S101413_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
S101413_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
S101413_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
S101413_RS00195	COG3853	Toxic anion resistance protein (TelA)
S101413_RS00200	COG1982	Orn Lys Arg decarboxylase major
S101413_RS00210	COG3870	Protein conserved in bacteria
S101413_RS00215	COG1728	Protein conserved in bacteria
S101413_RS00220	COG0470	DNA polymerase III
S101413_RS00225	COG1774	PSP1 C-terminal conserved region
S101413_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
S101413_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
S101413_RS00250	COG2002	toxin-antitoxin pair type II binding
S101413_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101413_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101413_RS00260	COG0084	hydrolase, TatD family'
S101413_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101413_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
S101413_RS00285	COG4466	Protein conserved in bacteria
S101413_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
S101413_RS00305	COG0251	oxidation-reduction process
S101413_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
S101413_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
S101413_RS00345	COG2002	toxin-antitoxin pair type II binding
S101413_RS00350	COG2244	polysaccharide biosynthetic process
S101413_RS00355	COG3956	TIGRFAM MazG family protein
S101413_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
S101413_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
S101413_RS00380	COG1098	S1 RNA binding domain
S101413_RS00395	COG2208	phosphoserine phosphatase activity
S101413_RS00400	COG2304	oxidoreductase activity
S101413_RS00405	COG0515	serine threonine protein kinase
S101413_RS00410	COG0037	tRNA processing
S101413_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
S101413_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
S101413_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101413_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101413_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101413_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
S101413_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101413_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
S101413_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
S101413_RS00475	COG1396	sequence-specific DNA binding
S101413_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101413_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
S101413_RS00565	COG4463	regulation of RNA biosynthetic process
S101413_RS00570	COG3880	PFAM UvrB UvrC protein
S101413_RS00580	COG0542	response to heat
S101413_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
S101413_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
S101413_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
S101413_RS00615	COG1045	serine acetyltransferase
S101413_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
S101413_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101413_RS00635	COG3688	RNA-binding protein containing a PIN domain
S101413_RS00640	COG1595	DNA-templated transcription, initiation
S101413_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101413_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
S101413_RS00695	COG1358	cellular component organization or biogenesis
S101413_RS00720	COG0596	Alpha beta hydrolase
S101413_RS00830	COG0201	protein transport
S101413_RS00840	COG0024	Methionine aminopeptidase
S101413_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
S101413_RS00885	COG1122	ATPase activity
S101413_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101413_RS00910	COG2226	methyltransferase
S101413_RS00915	COG2318	DinB family
S101413_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101413_RS00930	COG0489	protein tyrosine kinase activity
S101413_RS00940	COG2194	sulfuric ester hydrolase activity
S101413_RS00945	COG0726	polysaccharide deacetylase
S101413_RS01005	COG0738	Major facilitator superfamily
S101413_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101413_RS01020	COG1063	alcohol dehydrogenase
S101413_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
S101413_RS01030	COG0385	Bile acid
S101413_RS01035	COG2819	hydrolase of the alpha beta superfamily
S101413_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101413_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101413_RS01055	COG2207	Transcriptional regulator
S101413_RS01060	COG3876	Protein conserved in bacteria
S101413_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101413_RS01075	COG1263	PTS System
S101413_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101413_RS01090	COG1683	Conserved Protein
S101413_RS01120	COG1595	DNA-templated transcription, initiation
S101413_RS01125	COG5662	AntiSigma factor
S101413_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101413_RS01135	COG4856	YbbR-like protein
S101413_RS01175	COG1063	alcohol dehydrogenase
S101413_RS01185	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS01225	COG1346	cytolysis
S101413_RS01230	COG1380	Effector of murein hydrolase LrgA
S101413_RS01235	COG1846	Transcriptional regulator
S101413_RS01240	COG1113	amino acid transport
S101413_RS01245	COG1011	Hydrolase
S101413_RS01250	COG4585	Histidine kinase
S101413_RS01255	COG2197	response regulator
S101413_RS01260	COG1131	(ABC) transporter
S101413_RS01300	COG0531	amino acid
S101413_RS01325	COG0584	glycerophosphoryl diester phosphodiesterase
S101413_RS01330	COG2271	Major facilitator Superfamily
S101413_RS01345	COG2368	4-hydroxyphenylacetate
S101413_RS01355	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS01370	COG0371	Dehydrogenase
S101413_RS01380	COG1183	phosphatidylcholine synthase activity
S101413_RS01385	COG0586	Pfam SNARE associated Golgi protein
S101413_RS01390	COG0688	phosphatidylethanolamine metabolic process
S101413_RS01405	COG1301	dicarboxylic acid transport
S101413_RS01410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101413_RS01415	COG0833	amino acid
S101413_RS01420	COG2040	homocysteine
S101413_RS01425	COG1115	amino acid carrier protein
S101413_RS01430	COG2066	Belongs to the glutaminase family
S101413_RS01435	COG4191	Histidine kinase
S101413_RS01440	COG0784	Response regulator, receiver
S101413_RS01445	COG3173	Aminoglycoside phosphotransferase
S101413_RS01465	COG3773	Cell wall hydrolase
S101413_RS01475	COG3540	Alkaline phosphatase
S101413_RS01480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101413_RS01485	COG0805	protein transport
S101413_RS01495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101413_RS01500	COG0477	Major facilitator Superfamily
S101413_RS01505	COG1309	transcriptional regulator
S101413_RS01510	COG0252	asparaginase activity
S101413_RS01515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
S101413_RS01525	COG0667	Aldo Keto reductase
S101413_RS01535	COG1595	DNA-templated transcription, initiation
S101413_RS01540	COG1595	DNA-templated transcription, initiation
S101413_RS01545	COG1876	peptidase activity
S101413_RS01550	COG0457	Tetratricopeptide repeat
S101413_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS01575	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101413_RS01580	COG1121	(ABC) transporter
S101413_RS01585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101413_RS01590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS01595	COG2310	stress, protein
S101413_RS01600	COG2310	stress, protein
S101413_RS01605	COG2310	stress, protein
S101413_RS01610	COG0861	Integral membrane protein TerC family
S101413_RS01620	COG3853	Toxic anion resistance protein (TelA)
S101413_RS01635	COG4176	ABC-type proline glycine betaine transport system permease component
S101413_RS01640	COG2113	Glycine betaine
S101413_RS01645	COG1473	amidohydrolase
S101413_RS01650	COG1288	antiporter activity
S101413_RS01660	COG0366	Alpha amylase catalytic
S101413_RS01670	COG2814	Major facilitator Superfamily
S101413_RS01675	COG1846	Transcriptional regulator
S101413_RS01680	COG1280	lysine exporter protein (LysE YggA)
S101413_RS01685	COG3403	YqcI/YcgG family
S101413_RS01690	COG1113	amino acid transport
S101413_RS01695	COG3665	Urea carboxylase-associated protein
S101413_RS01710	COG1660	Displays ATPase and GTPase activities
S101413_RS01720	COG2271	Major facilitator Superfamily
S101413_RS01725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
S101413_RS01730	COG3458	cephalosporin-C deacetylase activity
S101413_RS01740	COG0506	proline dehydrogenase activity
S101413_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS01750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101413_RS01765	COG1587	Uroporphyrinogen-III synthase
S101413_RS01765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101413_RS01770	COG2146	nitrite reductase [NAD(P)H] activity
S101413_RS01775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101413_RS01785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
S101413_RS01790	COG2223	nitrite transmembrane transporter activity
S101413_RS01795	COG0523	cobalamin synthesis protein
S101413_RS01800	COG1063	alcohol dehydrogenase
S101413_RS01805	COG1714	RDD family
S101413_RS01815	COG2723	6-phospho-beta-galactosidase activity
S101413_RS01825	COG3209	COG3209 Rhs family protein
S101413_RS01830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
S101413_RS01835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
S101413_RS01840	COG1733	regulation of RNA biosynthetic process
S101413_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS01860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
S101413_RS01875	COG2364	Membrane
S101413_RS01880	COG1126	abc transporter atp-binding protein
S101413_RS01885	COG0765	amino acid transport
S101413_RS01895	COG0583	DNA-binding transcription factor activity
S101413_RS01900	COG0163	prenyltransferase activity
S101413_RS01905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
S101413_RS01920	COG3104	oligopeptide transport
S101413_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS01935	COG0697	spore germination
S101413_RS01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS01955	COG0456	acetyltransferase
S101413_RS01960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101413_RS01965	COG0765	amino acid transport
S101413_RS01970	COG1126	abc transporter atp-binding protein
S101413_RS01975	COG1473	amidohydrolase
S101413_RS01980	COG2079	MmgE PrpD family protein
S101413_RS01985	COG1136	(ABC) transporter
S101413_RS01990	COG0577	efflux transmembrane transporter activity
S101413_RS02000	COG3850	Histidine kinase
S101413_RS02000	COG5002	protein histidine kinase activity
S101413_RS02005	COG0457	Tetratricopeptide repeat
S101413_RS02020	COG0527	aspartate kinase activity
S101413_RS02030	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS02035	COG4605	iron ion homeostasis
S101413_RS02040	COG4604	ABC transporter, ATP-binding protein
S101413_RS02045	COG4607	ABC-type enterochelin transport system periplasmic component
S101413_RS02050	COG2814	Major facilitator Superfamily
S101413_RS02055	COG1309	transcriptional regulator
S101413_RS02060	COG0778	Nitroreductase
S101413_RS02065	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101413_RS02070	COG0640	Transcriptional regulator
S101413_RS02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101413_RS02080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
S101413_RS02085	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS02090	COG4975	Glucose uptake
S101413_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS02100	COG4549	nuclear export factor GLE1
S101413_RS02105	COG1276	copper resistance
S101413_RS02105	COG2372	response to copper ion
S101413_RS02110	COG1349	DNA-binding transcription factor activity
S101413_RS02120	COG2213	PTS system mannitol-specific
S101413_RS02125	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS02135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
S101413_RS02145	COG0561	phosphatase activity
S101413_RS02155	COG1914	H( )-stimulated, divalent metal cation uptake system
S101413_RS02165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
S101413_RS02170	COG1984	allophanate hydrolase subunit 2
S101413_RS02175	COG1414	Transcriptional regulator
S101413_RS02180	COG2755	lipolytic protein G-D-S-L family
S101413_RS02190	COG2329	Antibiotic biosynthesis monooxygenase
S101413_RS02195	COG0768	penicillin binding
S101413_RS02200	COG4989	oxidoreductase activity
S101413_RS02210	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS02220	COG1917	Cupin 2, conserved barrel domain protein
S101413_RS02225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101413_RS02230	COG3871	stress protein (general stress protein 26)
S101413_RS02240	COG2814	Major facilitator Superfamily
S101413_RS02245	COG1522	sequence-specific DNA binding
S101413_RS02250	COG0551	DNA topoisomerase type I activity
S101413_RS02250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101413_RS02255	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
S101413_RS02260	COG3706	GGDEF domain
S101413_RS02265	COG5298	Protein conserved in bacteria
S101413_RS02280	COG0531	amino acid
S101413_RS02285	COG0494	nUDIX hydrolase
S101413_RS02290	COG0028	Belongs to the TPP enzyme family
S101413_RS02295	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS02295	COG1388	LysM domain
S101413_RS02295	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS02315	COG0457	Tetratricopeptide repeat
S101413_RS02345	COG1914	H( )-stimulated, divalent metal cation uptake system
S101413_RS02360	COG4876	unkown
S101413_RS02375	COG2217	Heavy metal translocating P-type atpase
S101413_RS02380	COG3729	General stress protein
S101413_RS02385	COG0662	Cupin 2, conserved barrel domain protein
S101413_RS02390	COG2329	Antibiotic biosynthesis monooxygenase
S101413_RS02395	COG3546	catalase activity
S101413_RS02400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
S101413_RS02410	COG4565	transcriptional regulatory protein
S101413_RS02415	COG1301	dicarboxylic acid transport
S101413_RS02420	COG0628	permease
S101413_RS02425	COG1131	(ABC) transporter
S101413_RS02430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101413_RS02440	COG1960	acyl-CoA dehydrogenase activity
S101413_RS02455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101413_RS02460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS02470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
S101413_RS02475	COG0513	Belongs to the DEAD box helicase family
S101413_RS02480	COG3402	PFAM membrane-flanked domain
S101413_RS02485	COG3428	Bacterial PH domain
S101413_RS02490	COG0705	Rhomboid family
S101413_RS02500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
S101413_RS02505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101413_RS02510	COG0864	Transcriptional regulator
S101413_RS02515	COG2337	Toxic component of a toxin-antitoxin (TA) module
S101413_RS02520	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS02525	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS02530	COG2172	sigma factor antagonist activity
S101413_RS02535	COG2208	phosphoserine phosphatase activity
S101413_RS02540	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS02550	COG1191	sigma factor activity
S101413_RS02555	COG2208	phosphoserine phosphatase activity
S101413_RS02560	COG2183	response to ionizing radiation
S101413_RS02610	COG0582	viral genome integration into host DNA
S101413_RS02615	COG2856	Zn peptidase
S101413_RS02640	COG1674	ftsk spoiiie
S101413_RS02645	COG2946	Replication initiation factor
S101413_RS02715	COG0741	lytic transglycosylase activity
S101413_RS02715	COG0791	NLP P60 protein
S101413_RS02740	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101413_RS02750	COG0477	Major facilitator Superfamily
S101413_RS02770	COG2030	dehydratase
S101413_RS02785	COG1959	2 iron, 2 sulfur cluster binding
S101413_RS02790	COG2910	NAD(P)H-binding
S101413_RS02800	COG1309	transcriptional regulator
S101413_RS02805	COG3239	Fatty acid desaturase
S101413_RS02815	COG1278	Cold shock
S101413_RS02820	COG1329	Transcriptional regulator
S101413_RS02825	COG1794	racemase activity, acting on amino acids and derivatives
S101413_RS02840	COG3621	Patatin-like phospholipase
S101413_RS02850	COG0662	Cupin 2, conserved barrel domain protein
S101413_RS02865	COG0277	FAD linked oxidase domain protein
S101413_RS02890	COG0662	Cupin 2, conserved barrel domain protein
S101413_RS02895	COG2318	DinB family
S101413_RS02900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
S101413_RS02925	COG1064	alcohol dehydrogenase
S101413_RS02930	COG0789	Transcriptional regulator
S101413_RS02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101413_RS02955	COG2814	Major facilitator Superfamily
S101413_RS02960	COG1309	transcriptional regulator
S101413_RS02965	COG5577	PFAM Coat F domain
S101413_RS02975	COG1063	alcohol dehydrogenase
S101413_RS02980	COG5577	PFAM Coat F domain
S101413_RS02995	COG4585	Histidine kinase
S101413_RS03000	COG2197	response regulator
S101413_RS03005	COG2409	Drug exporters of the RND superfamily
S101413_RS03010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
S101413_RS03015	COG0488	(ABC) transporter
S101413_RS03020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101413_RS03025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS03035	COG2814	Major facilitator Superfamily
S101413_RS03040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101413_RS03050	COG0730	response to heat
S101413_RS03055	COG0456	acetyltransferase
S101413_RS03060	COG0789	Transcriptional regulator
S101413_RS03060	COG4978	Transcriptional regulator
S101413_RS03065	COG0697	spore germination
S101413_RS03070	COG1051	belongs to the nudix hydrolase family
S101413_RS03075	COG2226	methyltransferase
S101413_RS03080	COG0473	3-isopropylmalate dehydrogenase activity
S101413_RS03085	COG1802	Transcriptional regulator
S101413_RS03090	COG1819	glycosyl
S101413_RS03105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
S101413_RS03110	COG1388	LysM domain
S101413_RS03115	COG2814	Major facilitator Superfamily
S101413_RS03120	COG2188	Transcriptional regulator
S101413_RS03125	COG2186	Transcriptional regulator
S101413_RS03130	COG2807	transmembrane transport
S101413_RS03135	COG2076	Multidrug Resistance protein
S101413_RS03140	COG2076	Multidrug Resistance protein
S101413_RS03145	COG1309	transcriptional regulator
S101413_RS03150	COG0531	amino acid
S101413_RS03160	COG3832	glyoxalase III activity
S101413_RS03165	COG0604	alcohol dehydrogenase
S101413_RS03175	COG2814	Major facilitator Superfamily
S101413_RS03215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
S101413_RS03225	COG1214	PFAM Peptidase M22, glycoprotease
S101413_RS03230	COG0456	acetyltransferase
S101413_RS03235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
S101413_RS03255	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
S101413_RS03260	COG0805	protein transport
S101413_RS03270	COG1266	CAAX protease self-immunity
S101413_RS03285	COG0156	8-amino-7-oxononanoate synthase activity
S101413_RS03310	COG3403	YqcI/YcgG family
S101413_RS03330	COG2814	Major facilitator Superfamily
S101413_RS03335	COG0457	Tetratricopeptide repeat
S101413_RS03345	COG2211	Major facilitator Superfamily
S101413_RS03350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101413_RS03360	COG1842	Phage shock protein A
S101413_RS03365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101413_RS03370	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
S101413_RS03375	COG4260	virion core protein, lumpy skin disease virus
S101413_RS03380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
S101413_RS03380	COG2755	lipolytic protein G-D-S-L family
S101413_RS03390	COG1595	DNA-templated transcription, initiation
S101413_RS03395	COG1063	alcohol dehydrogenase
S101413_RS03400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
S101413_RS03405	COG0823	Involved in the tonB-independent uptake of proteins
S101413_RS03430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101413_RS03435	COG0714	Associated with various cellular activities
S101413_RS03475	COG2211	Major facilitator Superfamily
S101413_RS03490	COG2252	PERMEase
S101413_RS03495	COG3064	Membrane
S101413_RS03515	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
S101413_RS03525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
S101413_RS03530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
S101413_RS03535	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
S101413_RS03550	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
S101413_RS03560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
S101413_RS03565	COG0138	bifunctional purine biosynthesis protein purh
S101413_RS03570	COG0151	Belongs to the GarS family
S101413_RS03580	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
S101413_RS03585	COG1470	cell adhesion involved in biofilm formation
S101413_RS03590	COG4496	protein, YerC YecD
S101413_RS03595	COG0069	glutamate synthase activity
S101413_RS03610	COG0210	DNA helicase
S101413_RS03620	COG4851	CamS sex pheromone cAM373 precursor
S101413_RS03625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101413_RS03630	COG1285	pathogenesis
S101413_RS03635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101413_RS03655	COG1309	transcriptional regulator
S101413_RS03660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
S101413_RS03665	COG1597	lipid kinase activity
S101413_RS03670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101413_RS03675	COG2197	response regulator
S101413_RS03685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS03695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101413_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS03710	COG1131	(ABC) transporter
S101413_RS03740	COG5444	nuclease activity
S101413_RS03750	COG5444	nuclease activity
S101413_RS03780	COG3546	catalase activity
S101413_RS03785	COG0454	-acetyltransferase
S101413_RS03795	COG2323	membrane
S101413_RS03800	COG2329	Antibiotic biosynthesis monooxygenase
S101413_RS03805	COG0346	lactoylglutathione lyase activity
S101413_RS03815	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS03820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
S101413_RS03825	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
S101413_RS03830	COG4208	sulfate ABC transporter
S101413_RS03840	COG5583	Uncharacterized small protein (DUF2292)
S101413_RS03845	COG0196	riboflavin kinase activity
S101413_RS03850	COG0670	Belongs to the BI1 family
S101413_RS03860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101413_RS03870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101413_RS03870	COG2124	cytochrome p450
S101413_RS03885	COG1131	(ABC) transporter
S101413_RS03900	COG1368	sulfuric ester hydrolase activity
S101413_RS03905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
S101413_RS03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101413_RS03915	COG1442	glycosyl transferase family 8
S101413_RS03920	COG1216	Glycosyl transferase, family 2
S101413_RS03925	COG1442	glycosyl transferase family 8
S101413_RS03930	COG2223	nitrite transmembrane transporter activity
S101413_RS03935	COG0531	amino acid
S101413_RS03940	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS03955	COG0463	Glycosyl transferase, family 2
S101413_RS03955	COG0457	Tetratricopeptide repeat
S101413_RS03960	COG0488	(ABC) transporter
S101413_RS03970	COG2814	Major facilitator Superfamily
S101413_RS03975	COG0488	(ABC) transporter
S101413_RS03980	COG0513	Belongs to the DEAD box helicase family
S101413_RS04005	COG3866	Pectate lyase
S101413_RS04010	COG0471	metal ion transport
S101413_RS04055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS04060	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
S101413_RS04070	COG2258	MOSC domain
S101413_RS04090	COG0024	Methionine aminopeptidase
S101413_RS04095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS04095	COG1263	PTS System
S101413_RS04105	COG1368	sulfuric ester hydrolase activity
S101413_RS04115	COG0071	Belongs to the small heat shock protein (HSP20) family
S101413_RS04130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS04130	COG1263	PTS System
S101413_RS04135	COG0366	Alpha amylase catalytic
S101413_RS04140	COG2188	Transcriptional regulator
S101413_RS04145	COG0778	Nitroreductase
S101413_RS04165	COG0693	protein deglycase activity
S101413_RS04185	COG2814	Major facilitator Superfamily
S101413_RS04200	COG4980	gas vesicle protein
S101413_RS04205	COG1295	ribonuclease BN
S101413_RS04210	COG0477	Major facilitator Superfamily
S101413_RS04215	COG0387	Pfam Sodium calcium exchanger
S101413_RS04225	COG0668	transmembrane transport
S101413_RS04230	COG0535	radical SAM domain protein
S101413_RS04240	COG0726	polysaccharide deacetylase
S101413_RS04245	COG2084	Dehydrogenase
S101413_RS04255	COG0598	Magnesium transport protein CorA
S101413_RS04260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
S101413_RS04265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
S101413_RS04275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
S101413_RS04280	COG4637	Psort location Cytoplasmic, score
S101413_RS04285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101413_RS04290	COG0022	dehydrogenase e1 component
S101413_RS04295	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101413_RS04300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101413_RS04305	COG3284	Transcriptional regulator
S101413_RS04315	COG1486	melibiose metabolic process
S101413_RS04320	COG1737	Transcriptional regulator
S101413_RS04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS04325	COG1263	PTS System
S101413_RS04330	COG1132	(ABC) transporter
S101413_RS04335	COG1132	(ABC) transporter
S101413_RS04340	COG2259	Doxx family
S101413_RS04345	COG2514	catechol 2,3-dioxygenase activity
S101413_RS04360	COG1695	Transcriptional regulator
S101413_RS04365	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101413_RS04370	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
S101413_RS04375	COG0574	Belongs to the PEP-utilizing enzyme family
S101413_RS04375	COG3848	Pyruvate phosphate dikinase
S101413_RS04380	COG2732	(Barnase) inhibitor
S101413_RS04385	COG2318	DinB family
S101413_RS04390	COG2814	Major facilitator Superfamily
S101413_RS04395	COG1846	Transcriptional regulator
S101413_RS04400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
S101413_RS04400	COG0392	lysyltransferase activity
S101413_RS04405	COG0384	phenazine biosynthesis protein PhzF
S101413_RS04410	COG0778	Nitroreductase
S101413_RS04425	COG1090	epimerase
S101413_RS04440	COG2814	Major facilitator Superfamily
S101413_RS04450	COG3591	Belongs to the peptidase S1B family
S101413_RS04465	COG3103	Sh3 type 3 domain protein
S101413_RS04470	COG5658	integral membrane protein
S101413_RS04475	COG0596	Alpha beta hydrolase
S101413_RS04480	COG0463	Glycosyl transferase, family 2
S101413_RS04485	COG4485	Bacterial membrane protein, YfhO
S101413_RS04490	COG1988	membrane-bound metal-dependent
S101413_RS04495	COG1194	a g-specific adenine glycosylase
S101413_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS04530	COG4129	membrane
S101413_RS04540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
S101413_RS04545	COG0735	belongs to the Fur family
S101413_RS04685	COG5577	PFAM Coat F domain
S101413_RS04690	COG3340	Belongs to the peptidase S51 family
S101413_RS04700	COG0277	FAD linked oxidase domain protein
S101413_RS04710	COG0747	negative chemotaxis
S101413_RS04720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101413_RS04725	COG0444	Belongs to the ABC transporter superfamily
S101413_RS04730	COG4608	Belongs to the ABC transporter superfamily
S101413_RS04735	COG0753	catalase activity
S101413_RS04750	COG1116	anion transmembrane transporter activity
S101413_RS04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101413_RS04760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101413_RS04785	COG1476	TRANSCRIPTIONal
S101413_RS04795	COG3382	B3 4 domain protein
S101413_RS04800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
S101413_RS04810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
S101413_RS04820	COG1664	Polymer-forming cytoskeletal
S101413_RS04825	COG1664	Polymer-forming cytoskeletal
S101413_RS04845	COG1846	Transcriptional regulator
S101413_RS04850	COG1566	PFAM secretion protein HlyD family protein
S101413_RS04855	COG2814	Major facilitator Superfamily
S101413_RS04860	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101413_RS04875	COG1725	Transcriptional regulator
S101413_RS04880	COG1131	(ABC) transporter
S101413_RS04885	COG1131	(ABC) transporter
S101413_RS04890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101413_RS04900	COG1278	Cold shock
S101413_RS04910	COG1464	Belongs to the NlpA lipoprotein family
S101413_RS04920	COG1823	symporter activity
S101413_RS04940	COG5577	PFAM Coat F domain
S101413_RS04945	COG0737	Belongs to the 5'-nucleotidase family
S101413_RS04945	COG1525	nuclease
S101413_RS04945	COG4085	toxin activity
S101413_RS04965	COG0517	IMP dehydrogenase activity
S101413_RS04970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101413_RS04975	COG3153	acetyltransferase
S101413_RS04975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101413_RS04985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101413_RS04990	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
S101413_RS04995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
S101413_RS05010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
S101413_RS05015	COG4585	Histidine kinase
S101413_RS05015	COG2203	Gaf domain
S101413_RS05020	COG2197	response regulator
S101413_RS05025	COG0431	NADPH-dependent FMN reductase
S101413_RS05040	COG1388	LysM domain
S101413_RS05040	COG0791	NLP P60 protein
S101413_RS05045	COG1959	2 iron, 2 sulfur cluster binding
S101413_RS05050	COG0668	transmembrane transport
S101413_RS05055	COG2719	SpoVR family
S101413_RS05060	COG1785	Belongs to the alkaline phosphatase family
S101413_RS05065	COG0791	NLP P60 protein
S101413_RS05065	COG1388	LysM domain
S101413_RS05070	COG0583	DNA-binding transcription factor activity
S101413_RS05075	COG0372	Belongs to the citrate synthase family
S101413_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS05085	COG0531	amino acid
S101413_RS05090	COG0733	neurotransmitter:sodium symporter activity
S101413_RS05110	COG0204	Acyl-transferase
S101413_RS05115	COG1253	flavin adenine dinucleotide binding
S101413_RS05120	COG0789	Transcriptional regulator
S101413_RS05125	COG0436	Aminotransferase
S101413_RS05130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101413_RS05135	COG1253	flavin adenine dinucleotide binding
S101413_RS05140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101413_RS05145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
S101413_RS05150	COG0584	glycerophosphoryl diester phosphodiesterase
S101413_RS05160	COG0668	transmembrane transport
S101413_RS05165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
S101413_RS05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101413_RS05180	COG3226	Transcriptional regulator
S101413_RS05190	COG0589	response to stress
S101413_RS05200	COG1132	(ABC) transporter
S101413_RS05210	COG0702	epimerase
S101413_RS05230	COG0189	ligase activity
S101413_RS05235	COG0189	ligase activity
S101413_RS05250	COG4335	DNA alkylation repair
S101413_RS05255	COG0561	phosphatase activity
S101413_RS05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101413_RS05270	COG0475	glutathione-regulated potassium exporter activity
S101413_RS05275	COG0490	domain, Protein
S101413_RS05285	COG1024	Enoyl-CoA hydratase
S101413_RS05295	COG4152	abc transporter atp-binding protein
S101413_RS05300	COG1668	transmembrane transport
S101413_RS05305	COG0420	3'-5' exonuclease activity
S101413_RS05325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
S101413_RS05365	COG4980	gas vesicle protein
S101413_RS05380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
S101413_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
S101413_RS05390	COG1131	(ABC) transporter
S101413_RS05395	COG4473	ABC transporter
S101413_RS05405	COG1473	amidohydrolase
S101413_RS05410	COG3069	C4-dicarboxylate transmembrane transporter activity
S101413_RS05415	COG2329	Antibiotic biosynthesis monooxygenase
S101413_RS05420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101413_RS05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
S101413_RS05440	COG1309	transcriptional regulator
S101413_RS05445	COG1511	domain protein
S101413_RS05450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101413_RS05460	COG1363	Peptidase, m42
S101413_RS05465	COG1301	dicarboxylic acid transport
S101413_RS05475	COG1234	tRNA 3'-trailer cleavage
S101413_RS05480	COG0095	Lipoate-protein ligase
S101413_RS05485	COG0702	epimerase
S101413_RS05490	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS05500	COG0501	Belongs to the peptidase M48B family
S101413_RS05505	COG1404	Belongs to the peptidase S8 family
S101413_RS05520	COG0406	alpha-ribazole phosphatase activity
S101413_RS05525	COG0183	Belongs to the thiolase family
S101413_RS05530	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS05535	COG1268	BioY protein
S101413_RS05540	COG0840	transmembrane signaling receptor activity
S101413_RS05545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101413_RS05545	COG0723	plastoquinol--plastocyanin reductase activity
S101413_RS05550	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS05560	COG4903	ComK protein
S101413_RS05570	COG5646	InterPro IPR014922
S101413_RS05595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101413_RS05610	COG0398	Pfam SNARE associated Golgi protein
S101413_RS05615	COG0681	Belongs to the peptidase S26 family
S101413_RS05620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
S101413_RS05625	COG1846	Transcriptional regulator
S101413_RS05630	COG3180	Ammonia monooxygenase
S101413_RS05635	COG2814	Major facilitator Superfamily
S101413_RS05645	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
S101413_RS05650	COG2323	membrane
S101413_RS05665	COG0420	3'-5' exonuclease activity
S101413_RS05675	COG1403	HNH endonuclease
S101413_RS05730	COG0367	asparagine synthase
S101413_RS05735	COG1562	ergosterol biosynthetic process
S101413_RS05740	COG0534	Mate efflux family protein
S101413_RS05745	COG1917	Cupin 2, conserved barrel domain protein
S101413_RS05745	COG2207	Transcriptional regulator
S101413_RS05750	COG1609	Transcriptional regulator
S101413_RS05755	COG0673	inositol 2-dehydrogenase activity
S101413_RS05760	COG2318	DinB family
S101413_RS05765	COG1279	arginine transmembrane transporter activity
S101413_RS05770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101413_RS05775	COG1357	PFAM Pentapeptide repeats (8 copies)
S101413_RS05780	COG2153	protein acetylation
S101413_RS05785	COG0646	methionine synthase
S101413_RS05785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
S101413_RS05795	COG2996	Protein conserved in bacteria
S101413_RS05800	COG1744	ABC transporter substrate-binding protein PnrA-like
S101413_RS05810	COG2124	cytochrome p450
S101413_RS05820	COG1307	EDD domain protein, DegV family
S101413_RS05825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS05840	COG0561	phosphatase activity
S101413_RS05845	COG1073	alpha beta
S101413_RS05850	COG2151	metal-sulfur cluster biosynthetic enzyme
S101413_RS05860	COG0277	FAD linked oxidase domain protein
S101413_RS05865	COG2271	Major facilitator Superfamily
S101413_RS05875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
S101413_RS05895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101413_RS05900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
S101413_RS05935	COG1744	ABC transporter substrate-binding protein PnrA-like
S101413_RS05950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101413_RS05955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
S101413_RS05960	COG5504	Zn-dependent protease
S101413_RS05970	COG4608	Belongs to the ABC transporter superfamily
S101413_RS05980	COG0601	transmembrane transport
S101413_RS05985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101413_RS05995	COG0180	Tryptophanyl-tRNA synthetase
S101413_RS06000	COG4166	transmembrane transport
S101413_RS06005	COG0601	transmembrane transport
S101413_RS06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101413_RS06015	COG0444	Belongs to the ABC transporter superfamily
S101413_RS06020	COG4608	Belongs to the ABC transporter superfamily
S101413_RS06030	COG0456	acetyltransferase
S101413_RS06035	COG1393	Belongs to the ArsC family
S101413_RS06040	COG0861	Integral membrane protein TerC family
S101413_RS06045	COG4862	establishment of competence for transformation
S101413_RS06050	COG4469	Competence protein
S101413_RS06055	COG1164	Oligoendopeptidase f
S101413_RS06060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101413_RS06065	COG2346	COG2346, Truncated hemoglobins
S101413_RS06070	COG0741	lytic transglycosylase activity
S101413_RS06075	COG4116	CYTH
S101413_RS06085	COG2357	RelA SpoT domain protein
S101413_RS06090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101413_RS06095	COG0564	pseudouridine synthase activity
S101413_RS06110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
S101413_RS06115	COG0352	thiamine-phosphate diphosphorylase activity
S101413_RS06120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
S101413_RS06125	COG2104	thiamine diphosphate biosynthetic process
S101413_RS06135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101413_RS06140	COG0351	phosphomethylpyrimidine kinase
S101413_RS06145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
S101413_RS06200	COG0210	DNA helicase
S101413_RS06220	COG1131	(ABC) transporter
S101413_RS06230	COG2153	protein acetylation
S101413_RS06240	COG2382	esterase
S101413_RS06245	COG0626	cystathionine gamma-synthase activity
S101413_RS06250	COG0626	cystathionine gamma-synthase activity
S101413_RS06305	COG1484	DNA-dependent DNA replication
S101413_RS06330	COG3655	Transcriptional regulator
S101413_RS06365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101413_RS06365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101413_RS06405	COG1780	Probably involved in ribonucleotide reductase function
S101413_RS06410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101413_RS06415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101413_RS06420	COG0756	dUTP diphosphatase activity
S101413_RS06430	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
S101413_RS06435	COG3584	3D domain protein
S101413_RS06475	COG1793	dna ligase
S101413_RS06530	COG0582	viral genome integration into host DNA
S101413_RS06615	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101413_RS06625	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS06645	COG4824	toxin secretion phage lysis holin
S101413_RS06650	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS06650	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS06685	COG0582	viral genome integration into host DNA
S101413_RS06790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
S101413_RS06845	COG3328	transposase activity
S101413_RS06920	COG5444	nuclease activity
S101413_RS06940	COG0135	phosphoribosylanthranilate isomerase activity
S101413_RS06955	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
S101413_RS06960	COG0477	Major facilitator Superfamily
S101413_RS06965	COG1846	Transcriptional regulator
S101413_RS06975	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101413_RS06980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101413_RS06985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101413_RS06990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS06990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS06995	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101413_RS07025	COG1285	pathogenesis
S101413_RS07040	COG2205	protein histidine kinase activity
S101413_RS07050	COG3383	formate dehydrogenase (NAD+) activity
S101413_RS07055	COG2427	Protein of unknown function (DUF1641)
S101413_RS07060	COG2124	cytochrome p450
S101413_RS07075	COG1587	Uroporphyrinogen-III synthase
S101413_RS07080	COG0390	transport system, permease component
S101413_RS07085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101413_RS07090	COG0697	spore germination
S101413_RS07095	COG4297	protein containing double-stranded beta helix domain
S101413_RS07105	COG1252	NADH dehydrogenase
S101413_RS07120	COG1609	Transcriptional regulator
S101413_RS07125	COG0246	Mannitol dehydrogenase
S101413_RS07130	COG2721	sulfolactate sulfo-lyase activity
S101413_RS07135	COG0745	RESPONSE REGULATOR receiver
S101413_RS07165	COG2197	response regulator
S101413_RS07195	COG0730	response to heat
S101413_RS07200	COG2318	DinB family
S101413_RS07205	COG0457	Tetratricopeptide repeat
S101413_RS07215	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS07215	COG1388	LysM domain
S101413_RS07215	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS07225	COG4195	phage-related replication protein
S101413_RS07230	COG2856	Zn peptidase
S101413_RS07235	COG1396	sequence-specific DNA binding
S101413_RS07245	COG1522	sequence-specific DNA binding
S101413_RS07250	COG1484	DNA-dependent DNA replication
S101413_RS07265	COG1595	DNA-templated transcription, initiation
S101413_RS07270	COG4193	domain, Protein
S101413_RS07305	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS07305	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS07320	COG0306	phosphate transporter
S101413_RS07325	COG1392	Phosphate transport regulator
S101413_RS07330	COG0531	amino acid
S101413_RS07335	COG0346	lactoylglutathione lyase activity
S101413_RS07340	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101413_RS07345	COG0463	Glycosyl transferase, family 2
S101413_RS07350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101413_RS07355	COG0477	Major facilitator Superfamily
S101413_RS07360	COG2362	D-Aminopeptidase
S101413_RS07365	COG0601	transmembrane transport
S101413_RS07370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
S101413_RS07375	COG0444	Belongs to the ABC transporter superfamily
S101413_RS07380	COG4166	transmembrane transport
S101413_RS07385	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101413_RS07390	COG4948	Mandelate Racemase Muconate Lactonizing
S101413_RS07395	COG0791	NLP P60 protein
S101413_RS07400	COG4608	Belongs to the ABC transporter superfamily
S101413_RS07405	COG2706	6-phosphogluconolactonase activity
S101413_RS07410	COG1834	amidinotransferase
S101413_RS07415	COG1607	acyl-coa hydrolase
S101413_RS07420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101413_RS07425	COG2076	Multidrug Resistance protein
S101413_RS07430	COG2076	Multidrug Resistance protein
S101413_RS07435	COG0788	formyltetrahydrofolate deformylase activity
S101413_RS07440	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101413_RS07450	COG1764	response to oxidative stress
S101413_RS07455	COG1846	Transcriptional regulator
S101413_RS07460	COG1764	response to oxidative stress
S101413_RS07490	COG2814	Major facilitator Superfamily
S101413_RS07495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101413_RS07505	COG1404	Belongs to the peptidase S8 family
S101413_RS07510	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS07515	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
S101413_RS07520	COG1122	ATPase activity
S101413_RS07525	COG4721	ABC-type cobalt transport system, permease component
S101413_RS07530	COG1388	LysM domain
S101413_RS07530	COG3858	chitin binding
S101413_RS07550	COG2239	Acts as a magnesium transporter
S101413_RS07555	COG0789	Transcriptional regulator
S101413_RS07570	COG1846	Transcriptional regulator
S101413_RS07575	COG0726	polysaccharide deacetylase
S101413_RS07580	COG1793	dna ligase
S101413_RS07580	COG3285	dna ligase
S101413_RS07585	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
S101413_RS07590	COG0586	Pfam SNARE associated Golgi protein
S101413_RS07595	COG0861	Integral membrane protein TerC family
S101413_RS07600	COG1191	sigma factor activity
S101413_RS07625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
S101413_RS07630	COG2323	membrane
S101413_RS07640	COG3594	Acyltransferase
S101413_RS07650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101413_RS07665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
S101413_RS07670	COG0436	Aminotransferase
S101413_RS07700	COG3852	Histidine kinase
S101413_RS07705	COG1846	Transcriptional regulator
S101413_RS07710	COG1360	Flagellar Motor Protein
S101413_RS07715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101413_RS07720	COG0542	response to heat
S101413_RS07730	COG3949	Membrane
S101413_RS07745	COG0720	synthase
S101413_RS07750	COG0602	queuosine metabolic process
S101413_RS07755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
S101413_RS07760	COG1733	regulation of RNA biosynthetic process
S101413_RS07765	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS07785	COG4873	Protein conserved in bacteria
S101413_RS07800	COG2244	polysaccharide biosynthetic process
S101413_RS07805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS07810	COG2217	Heavy metal translocating P-type atpase
S101413_RS07815	COG0006	proline dipeptidase activity
S101413_RS07820	COG1609	Transcriptional regulator
S101413_RS07825	COG3711	transcriptional antiterminator
S101413_RS07830	COG1263	PTS System
S101413_RS07830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS07830	COG2190	(PTS) system
S101413_RS07835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS07840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
S101413_RS07850	COG1533	DNA photolyase activity
S101413_RS07855	COG0840	transmembrane signaling receptor activity
S101413_RS07865	COG2340	Cysteine-rich secretory protein family
S101413_RS07870	COG0768	penicillin binding
S101413_RS07875	COG4191	Histidine kinase
S101413_RS07880	COG0436	Aminotransferase
S101413_RS07890	COG0784	Response regulator, receiver
S101413_RS07890	COG0835	chemotaxis
S101413_RS07900	COG2814	Major facilitator Superfamily
S101413_RS07905	COG1376	ErfK ybiS ycfS ynhG family protein
S101413_RS07910	COG1408	metallophosphoesterase
S101413_RS07925	COG2200	EAL domain
S101413_RS07930	COG4703	Protein of unknown function (DUF1797)
S101413_RS07935	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
S101413_RS07945	COG0517	IMP dehydrogenase activity
S101413_RS07950	COG0583	DNA-binding transcription factor activity
S101413_RS07955	COG0716	FMN binding
S101413_RS07965	COG0716	FMN binding
S101413_RS07985	COG0668	transmembrane transport
S101413_RS07990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS08010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101413_RS08015	COG0303	'Molybdopterin
S101413_RS08020	COG1763	Mo-molybdopterin cofactor biosynthetic process
S101413_RS08025	COG0314	molybdopterin synthase activity
S101413_RS08030	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
S101413_RS08040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
S101413_RS08045	COG1136	(ABC) transporter
S101413_RS08050	COG0577	efflux transmembrane transporter activity
S101413_RS08055	COG1349	DNA-binding transcription factor activity
S101413_RS08060	COG1105	Belongs to the carbohydrate kinase PfkB family
S101413_RS08065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101413_RS08065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101413_RS08065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS08070	COG0681	Belongs to the peptidase S26 family
S101413_RS08080	COG0488	(ABC) transporter
S101413_RS08085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101413_RS08110	COG2002	toxin-antitoxin pair type II binding
S101413_RS08120	COG2105	PFAM AIG2 family protein
S101413_RS08120	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
S101413_RS08135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
S101413_RS08150	COG0242	peptide deformylase activity
S101413_RS08160	COG0497	DNA recombination
S101413_RS08175	COG4221	oxidoreductase activity
S101413_RS08175	COG3321	synthase
S101413_RS08175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS08180	COG0300	oxidoreductase activity
S101413_RS08180	COG4221	oxidoreductase activity
S101413_RS08180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS08180	COG3321	synthase
S101413_RS08190	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS08190	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS08190	COG0300	oxidoreductase activity
S101413_RS08190	COG3321	synthase
S101413_RS08190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS08195	COG3321	synthase
S101413_RS08195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS08195	COG4221	oxidoreductase activity
S101413_RS08195	COG0300	oxidoreductase activity
S101413_RS08205	COG4221	oxidoreductase activity
S101413_RS08205	COG3321	synthase
S101413_RS08205	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS08205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS08215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101413_RS08220	COG0022	dehydrogenase e1 component
S101413_RS08225	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101413_RS08230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101413_RS08235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS08250	COG1982	Orn Lys Arg decarboxylase major
S101413_RS08275	COG0483	inositol monophosphate 1-phosphatase activity
S101413_RS08285	COG3227	Zinc metalloprotease (Elastase)
S101413_RS08300	COG1595	DNA-templated transcription, initiation
S101413_RS08320	COG1217	gtp-binding protein TYPA
S101413_RS08330	COG4896	Protein conserved in bacteria
S101413_RS08340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
S101413_RS08345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101413_RS08350	COG2066	Belongs to the glutaminase family
S101413_RS08385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101413_RS08390	COG1845	cytochrome c oxidase, subunit III
S101413_RS08395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
S101413_RS08400	COG3336	cytochrome c oxidase
S101413_RS08410	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
S101413_RS08415	COG2340	Cysteine-rich secretory protein family
S101413_RS08430	COG3679	Belongs to the UPF0342 family
S101413_RS08445	COG0742	ribosomal rna small subunit methyltransferase
S101413_RS08455	COG3314	Sporulation integral membrane protein YlbJ
S101413_RS08460	COG1752	Esterase of the alpha-beta hydrolase superfamily
S101413_RS08465	COG3480	Lon protease (S16) C-terminal proteolytic domain
S101413_RS08475	COG1399	metal-binding, possibly nucleic acid-binding protein
S101413_RS08495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
S101413_RS08515	COG4839	cell division protein FtsL
S101413_RS08520	COG0768	penicillin binding
S101413_RS08525	COG0768	penicillin binding
S101413_RS08545	COG0772	Belongs to the SEDS family
S101413_RS08560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
S101413_RS08565	COG0849	cell division
S101413_RS08570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
S101413_RS08585	COG1191	sigma factor activity
S101413_RS08590	COG1191	sigma factor activity
S101413_RS08595	COG1119	ATPase activity
S101413_RS08600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101413_RS08605	COG1873	PFAM PRC-barrel domain
S101413_RS08610	COG1496	oxidoreductase activity
S101413_RS08615	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
S101413_RS08625	COG0762	integral membrane protein
S101413_RS08630	COG2302	S4 RNA-binding domain
S101413_RS08635	COG3599	regulation of cell shape
S101413_RS08645	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
S101413_RS08650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101413_RS08660	COG0564	pseudouridine synthase activity
S101413_RS08670	COG2233	PERMEase
S101413_RS08680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
S101413_RS08685	COG0505	Belongs to the CarA family
S101413_RS08690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
S101413_RS08705	COG0284	orotidine-5'-phosphate decarboxylase activity
S101413_RS08710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
S101413_RS08720	COG0306	phosphate transporter
S101413_RS08735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
S101413_RS08745	COG1648	precorrin-2 dehydrogenase activity
S101413_RS08760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
S101413_RS08765	COG1561	YicC-like family, N-terminal region
S101413_RS08775	COG0194	GDP metabolic process
S101413_RS08785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101413_RS08790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
S101413_RS08795	COG0242	peptide deformylase activity
S101413_RS08805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
S101413_RS08805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
S101413_RS08815	COG0631	protein serine/threonine phosphatase activity
S101413_RS08830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
S101413_RS08835	COG1564	THIamine pyrophosphokinase
S101413_RS08850	COG1302	Protein conserved in bacteria
S101413_RS08855	COG1461	Dihydroxyacetone kinase
S101413_RS08860	COG1760	l-serine dehydratase
S101413_RS08865	COG1760	l-serine dehydratase
S101413_RS08870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
S101413_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS08905	COG1196	nuclear chromosome segregation
S101413_RS08925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
S101413_RS08935	COG1837	Belongs to the UPF0109 family
S101413_RS08960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101413_RS08975	COG2257	FlhB HrpN YscU SpaS Family
S101413_RS08985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
S101413_RS08990	COG0758	DNA mediated transformation
S101413_RS08995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
S101413_RS09005	COG4974	Belongs to the 'phage' integrase family
S101413_RS09025	COG1815	bacterial-type flagellum-dependent cell motility
S101413_RS09030	COG1558	bacterial-type flagellum-dependent cell motility
S101413_RS09035	COG1677	Flagellar hook-basal body complex protein FliE
S101413_RS09040	COG1766	The M ring may be actively involved in energy transduction
S101413_RS09045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101413_RS09050	COG1317	bacterial-type flagellum organization
S101413_RS09055	COG1157	protein secretion by the type III secretion system
S101413_RS09060	COG2882	bacterial-type flagellum organization
S101413_RS09065	COG3334	PFAM MgtE intracellular
S101413_RS09070	COG3144	bacterial-type flagellum assembly
S101413_RS09075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
S101413_RS09080	COG4786	Flagellar basal body rod
S101413_RS09085	COG1582	Flagellar protein (FlbD)
S101413_RS09090	COG1580	Controls the rotational direction of flagella during chemotaxis
S101413_RS09100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
S101413_RS09100	COG1776	CheC inhibitor of MCP methylation
S101413_RS09105	COG2201	protein-glutamate methylesterase activity
S101413_RS09115	COG1338	Plays a role in the flagellum-specific transport system
S101413_RS09120	COG1987	bacterial-type flagellum assembly
S101413_RS09130	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101413_RS09135	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
S101413_RS09140	COG1419	protein localization to endoplasmic reticulum
S101413_RS09145	COG0455	bacterial-type flagellum organization
S101413_RS09150	COG2201	protein-glutamate methylesterase activity
S101413_RS09155	COG2198	Histidine kinase
S101413_RS09155	COG0643	Histidine kinase
S101413_RS09160	COG0835	chemotaxis
S101413_RS09165	COG1776	CheC inhibitor of MCP methylation
S101413_RS09175	COG1191	sigma factor activity
S101413_RS09205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
S101413_RS09220	COG0750	zinc metalloprotease
S101413_RS09230	COG2176	DNA-directed DNA polymerase activity
S101413_RS09240	COG0195	Participates in both transcription termination and antitermination
S101413_RS09245	COG2740	Nucleic-acid-binding protein implicated in transcription termination
S101413_RS09250	COG1358	cellular component organization or biogenesis
S101413_RS09260	COG1550	Protein conserved in bacteria
S101413_RS09275	COG0196	riboflavin kinase activity
S101413_RS09290	COG0726	polysaccharide deacetylase
S101413_RS09300	COG1873	PFAM PRC-barrel domain
S101413_RS09305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101413_RS09310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
S101413_RS09315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
S101413_RS09335	COG0740	serine-type endopeptidase activity
S101413_RS09355	COG2814	Major facilitator Superfamily
S101413_RS09360	COG1846	Transcriptional regulator
S101413_RS09365	COG1033	growth of symbiont in host cell
S101413_RS09365	COG2409	Drug exporters of the RND superfamily
S101413_RS09370	COG0612	Peptidase, M16
S101413_RS09375	COG0612	Peptidase, M16
S101413_RS09380	COG0300	oxidoreductase activity
S101413_RS09395	COG1426	Protein conserved in bacteria
S101413_RS09400	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
S101413_RS09425	COG1692	metallophosphoesterase
S101413_RS09430	COG2359	stage V sporulation protein S
S101413_RS09450	COG4550	Control of competence regulator ComK, YlbF/YmcA
S101413_RS09515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS09520	COG3425	synthase
S101413_RS09525	COG1024	Enoyl-CoA hydratase
S101413_RS09535	COG4221	oxidoreductase activity
S101413_RS09535	COG0300	oxidoreductase activity
S101413_RS09535	COG3321	synthase
S101413_RS09535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS09560	COG2124	cytochrome p450
S101413_RS09565	COG3209	COG3209 Rhs family protein
S101413_RS09570	COG3619	membrane
S101413_RS09580	COG1404	Belongs to the peptidase S8 family
S101413_RS09590	COG4195	phage-related replication protein
S101413_RS09595	COG1764	response to oxidative stress
S101413_RS09605	COG2076	Multidrug Resistance protein
S101413_RS09645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101413_RS09650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
S101413_RS09655	COG4112	unkown
S101413_RS09660	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101413_RS09670	COG0464	growth
S101413_RS09675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
S101413_RS09680	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
S101413_RS09685	COG0789	Transcriptional regulator
S101413_RS09690	COG0174	glutamine synthetase
S101413_RS09730	COG1070	Carbohydrate kinase
S101413_RS09735	COG3848	Pyruvate phosphate dikinase
S101413_RS09735	COG0574	Belongs to the PEP-utilizing enzyme family
S101413_RS09760	COG2378	regulation of single-species biofilm formation
S101413_RS09765	COG2318	DinB family
S101413_RS09770	COG1064	alcohol dehydrogenase
S101413_RS09800	COG0456	acetyltransferase
S101413_RS09805	COG5444	nuclease activity
S101413_RS09870	COG3397	chitin binding
S101413_RS09890	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS09895	COG0756	dUTP diphosphatase activity
S101413_RS09900	COG4195	phage-related replication protein
S101413_RS09960	COG0785	Cytochrome C biogenesis protein
S101413_RS09965	COG2201	protein-glutamate methylesterase activity
S101413_RS09970	COG4846	Membrane protein involved in cytochrome C biogenesis
S101413_RS09980	COG0071	Belongs to the small heat shock protein (HSP20) family
S101413_RS09995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
S101413_RS10000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS10020	COG0824	Thioesterase
S101413_RS10030	COG4841	protein insertion into membrane
S101413_RS10040	COG1832	CoA-binding protein
S101413_RS10045	COG0187	DNA topoisomerase II activity
S101413_RS10060	COG1115	amino acid carrier protein
S101413_RS10075	COG0800	Aldolase
S101413_RS10080	COG1312	Catalyzes the dehydration of D-mannonate
S101413_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS10140	COG2205	protein histidine kinase activity
S101413_RS10145	COG0745	RESPONSE REGULATOR receiver
S101413_RS10155	COG3507	Belongs to the glycosyl hydrolase 43 family
S101413_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS10185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101413_RS10190	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101413_RS10195	COG2610	gluconate transmembrane transporter activity
S101413_RS10200	COG2124	cytochrome p450
S101413_RS10220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101413_RS10230	COG2246	polysaccharide biosynthetic process
S101413_RS10235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101413_RS10240	COG0586	Pfam SNARE associated Golgi protein
S101413_RS10245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101413_RS10250	COG1024	Enoyl-CoA hydratase
S101413_RS10255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
S101413_RS10265	COG0439	Biotin carboxylase
S101413_RS10270	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS10275	COG1960	acyl-CoA dehydrogenase activity
S101413_RS10290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS10290	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
S101413_RS10305	COG2323	membrane
S101413_RS10310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101413_RS10320	COG2323	membrane
S101413_RS10335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101413_RS10380	COG2027	D-alanyl-D-alanine carboxypeptidase
S101413_RS10385	COG2017	converts alpha-aldose to the beta-anomer
S101413_RS10405	COG0582	viral genome integration into host DNA
S101413_RS10410	COG0166	Belongs to the GPI family
S101413_RS10425	COG0640	Transcriptional regulator
S101413_RS10430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
S101413_RS10440	COG0604	alcohol dehydrogenase
S101413_RS10450	COG0493	'glutamate synthase
S101413_RS10455	COG0070	glutamate synthase
S101413_RS10455	COG0069	glutamate synthase activity
S101413_RS10455	COG0067	glutamate synthase
S101413_RS10460	COG0583	DNA-binding transcription factor activity
S101413_RS10465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
S101413_RS10480	COG0300	oxidoreductase activity
S101413_RS10485	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101413_RS10495	COG2814	Major facilitator Superfamily
S101413_RS10500	COG1070	Carbohydrate kinase
S101413_RS10545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101413_RS10550	COG2207	Transcriptional regulator
S101413_RS10550	COG0662	Cupin 2, conserved barrel domain protein
S101413_RS10555	COG1309	transcriptional regulator
S101413_RS10560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS10570	COG0640	Transcriptional regulator
S101413_RS10575	COG0741	lytic transglycosylase activity
S101413_RS10595	COG1619	proteins homologs of microcin C7 resistance protein MccF
S101413_RS10605	COG1388	LysM domain
S101413_RS10605	COG3584	3D domain protein
S101413_RS10610	COG0514	ATP-dependent DNA helicase (RecQ)
S101413_RS10620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
S101413_RS10625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101413_RS10640	COG0071	Belongs to the small heat shock protein (HSP20) family
S101413_RS10670	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS10675	COG1657	PFAM Prenyltransferase squalene oxidase
S101413_RS10680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101413_RS10685	COG0733	neurotransmitter:sodium symporter activity
S101413_RS10690	COG0385	Bile acid
S101413_RS10695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS10700	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101413_RS10720	COG2032	superoxide dismutase activity
S101413_RS10725	COG1388	LysM domain
S101413_RS10725	COG0791	NLP P60 protein
S101413_RS10730	COG1819	glycosyl
S101413_RS10735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
S101413_RS10740	COG0534	Mate efflux family protein
S101413_RS10745	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS10750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101413_RS10755	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101413_RS10765	COG2962	Rard protein
S101413_RS10780	COG1942	4-Oxalocrotonate Tautomerase
S101413_RS10790	COG1733	regulation of RNA biosynthetic process
S101413_RS10795	COG0778	Nitroreductase
S101413_RS10800	COG0400	carboxylic ester hydrolase activity
S101413_RS10805	COG0346	lactoylglutathione lyase activity
S101413_RS10815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
S101413_RS10825	COG2723	6-phospho-beta-galactosidase activity
S101413_RS10830	COG2188	Transcriptional regulator
S101413_RS10835	COG0793	Belongs to the peptidase S41A family
S101413_RS10835	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS10840	COG2226	methyltransferase
S101413_RS10850	COG1876	peptidase activity
S101413_RS10870	COG0671	phosphoesterase, PA-phosphatase related
S101413_RS10900	COG1509	lysine 2,3-aminomutase activity
S101413_RS10905	COG0456	acetyltransferase
S101413_RS10910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101413_RS10915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
S101413_RS10920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
S101413_RS10925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
S101413_RS10940	COG0456	acetyltransferase
S101413_RS10945	COG0463	Glycosyl transferase, family 2
S101413_RS10960	COG4641	Protein conserved in bacteria
S101413_RS10970	COG1086	Polysaccharide biosynthesis protein
S101413_RS10990	COG4698	Protein conserved in bacteria
S101413_RS10995	COG2755	lipolytic protein G-D-S-L family
S101413_RS11000	COG1999	signal sequence binding
S101413_RS11010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
S101413_RS11015	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
S101413_RS11020	COG1272	protein, Hemolysin III
S101413_RS11025	COG0204	Acyl-transferase
S101413_RS11030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101413_RS11045	COG2136	Putative SAM-dependent methyltransferase
S101413_RS11045	COG2521	methyltransferase
S101413_RS11060	COG1413	lyase activity
S101413_RS11065	COG1418	mRNA catabolic process
S101413_RS11070	COG0386	Belongs to the glutathione peroxidase family
S101413_RS11080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
S101413_RS11090	COG1278	Cold shock
S101413_RS11110	COG0328	RNA-DNA hybrid ribonuclease activity
S101413_RS11115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
S101413_RS11120	COG0328	RNA-DNA hybrid ribonuclease activity
S101413_RS11130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101413_RS11175	COG1335	isochorismatase
S101413_RS11185	COG2233	PERMEase
S101413_RS11195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
S101413_RS11200	COG1199	ATP-dependent helicase activity
S101413_RS11215	COG0116	Belongs to the methyltransferase superfamily
S101413_RS11255	COG2190	(PTS) system
S101413_RS11260	COG0071	Belongs to the small heat shock protein (HSP20) family
S101413_RS11300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101413_RS11300	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101413_RS11310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
S101413_RS11315	COG3935	DnaD domain protein
S101413_RS11325	COG0436	Aminotransferase
S101413_RS11370	COG0438	transferase activity, transferring glycosyl groups
S101413_RS11375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
S101413_RS11390	COG1694	Mazg nucleotide pyrophosphohydrolase
S101413_RS11395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS11410	COG4347	Protein of unknown function (DUF1405)
S101413_RS11415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101413_RS11415	COG2010	Cytochrome c
S101413_RS11420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
S101413_RS11425	COG0723	plastoquinol--plastocyanin reductase activity
S101413_RS11485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
S101413_RS11490	COG4401	Chorismate mutase type I
S101413_RS11510	COG0105	UTP biosynthetic process
S101413_RS11515	COG0142	geranyltranstransferase activity
S101413_RS11525	COG0142	geranyltranstransferase activity
S101413_RS11540	COG0776	regulation of translation
S101413_RS11545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
S101413_RS11585	COG0539	negative regulation of cytoplasmic translation
S101413_RS11595	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
S101413_RS11600	COG2959	enzyme of heme biosynthesis
S101413_RS11605	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS11605	COG3773	Cell wall hydrolase
S101413_RS11610	COG2339	peptidase activity
S101413_RS11615	COG0492	ferredoxin-NADP+ reductase activity
S101413_RS11620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101413_RS11625	COG4862	establishment of competence for transformation
S101413_RS11630	COG1408	metallophosphoesterase
S101413_RS11640	COG1388	LysM domain
S101413_RS11645	COG1266	CAAX protease self-immunity
S101413_RS11650	COG0514	ATP-dependent DNA helicase (RecQ)
S101413_RS11655	COG4955	Helix-turn-helix domain
S101413_RS11660	COG1141	Ferredoxin
S101413_RS11665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
S101413_RS11680	COG1595	DNA-templated transcription, initiation
S101413_RS11685	COG5002	protein histidine kinase activity
S101413_RS11690	COG0745	RESPONSE REGULATOR receiver
S101413_RS11695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101413_RS11700	COG1333	cytochrome c biogenesis protein
S101413_RS11705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS11710	COG1187	pseudouridine synthase activity
S101413_RS11715	COG0700	Nucleoside recognition
S101413_RS11720	COG2715	membrane protein required for spore maturation
S101413_RS11750	COG1547	Domain of unknown function (DUF309)
S101413_RS11760	COG0456	acetyltransferase
S101413_RS11775	COG0307	riboflavin synthase, alpha
S101413_RS11780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101413_RS11780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
S101413_RS11790	COG0681	Belongs to the peptidase S26 family
S101413_RS11800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
S101413_RS11805	COG4086	secreted protein
S101413_RS11810	COG0019	diaminopimelate decarboxylase activity
S101413_RS11815	COG0697	spore germination
S101413_RS11830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
S101413_RS11850	COG1191	sigma factor activity
S101413_RS11860	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS11870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
S101413_RS11875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
S101413_RS11890	COG0735	belongs to the Fur family
S101413_RS11895	COG1300	Membrane
S101413_RS11910	COG0281	malic enzyme
S101413_RS11915	COG1757	Na H antiporter
S101413_RS11920	COG1027	Aspartate ammonia-lyase
S101413_RS11925	COG0252	asparaginase activity
S101413_RS11930	COG1396	sequence-specific DNA binding
S101413_RS11935	COG1379	DNA repair
S101413_RS11940	COG0494	nUDIX hydrolase
S101413_RS11950	COG0667	Aldo Keto reductase
S101413_RS11960	COG1073	alpha beta
S101413_RS11970	COG4918	Iron-sulphur cluster biosynthesis
S101413_RS11980	COG2329	Antibiotic biosynthesis monooxygenase
S101413_RS11985	COG0456	acetyltransferase
S101413_RS12015	COG0346	lactoylglutathione lyase activity
S101413_RS12025	COG3048	D-serine ammonia-lyase activity
S101413_RS12030	COG0300	oxidoreductase activity
S101413_RS12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS12040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101413_RS12045	COG1024	Enoyl-CoA hydratase
S101413_RS12050	COG3425	synthase
S101413_RS12055	COG2124	cytochrome p450
S101413_RS12060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS12060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS12060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101413_RS12060	COG3321	synthase
S101413_RS12080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS12080	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS12080	COG3321	synthase
S101413_RS12080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
S101413_RS12080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
S101413_RS12095	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS12100	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS12115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
S101413_RS12115	COG2070	2-Nitropropane dioxygenase
S101413_RS12120	COG0250	Participates in transcription elongation, termination and antitermination
S101413_RS12145	COG0596	Alpha beta hydrolase
S101413_RS12160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
S101413_RS12165	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
S101413_RS12185	COG2195	Cleaves the N-terminal amino acid of tripeptides
S101413_RS12190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
S101413_RS12195	COG0346	lactoylglutathione lyase activity
S101413_RS12200	COG1376	ErfK ybiS ycfS ynhG family protein
S101413_RS12205	COG4129	membrane
S101413_RS12210	COG1126	abc transporter atp-binding protein
S101413_RS12215	COG0765	amino acid transport
S101413_RS12220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101413_RS12230	COG1597	lipid kinase activity
S101413_RS12235	COG0508	dehydrogenase complex catalyzes the overall conversion of
S101413_RS12245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
S101413_RS12250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
S101413_RS12255	COG3426	butyrate kinase activity
S101413_RS12260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101413_RS12265	COG0280	phosphate acetyltransferase
S101413_RS12270	COG3290	protein histidine kinase activity
S101413_RS12270	COG3829	transcription factor binding
S101413_RS12280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
S101413_RS12285	COG2079	MmgE PrpD family protein
S101413_RS12300	COG1250	3-hydroxyacyl-CoA dehydrogenase
S101413_RS12305	COG0183	Belongs to the thiolase family
S101413_RS12315	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101413_RS12340	COG1902	pentaerythritol trinitrate reductase activity
S101413_RS12355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
S101413_RS12360	COG0745	RESPONSE REGULATOR receiver
S101413_RS12365	COG0750	zinc metalloprotease
S101413_RS12370	COG0497	DNA recombination
S101413_RS12380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
S101413_RS12390	COG0142	geranyltranstransferase activity
S101413_RS12400	COG1570	exodeoxyribonuclease VII activity
S101413_RS12415	COG1302	Protein conserved in bacteria
S101413_RS12420	COG0439	Biotin carboxylase
S101413_RS12425	COG0511	ligase activity, forming carbon-carbon bonds
S101413_RS12465	COG3854	ATPases associated with a variety of cellular activities
S101413_RS12480	COG0006	proline dipeptidase activity
S101413_RS12490	COG3872	metal-dependent enzyme
S101413_RS12515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101413_RS12535	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
S101413_RS12550	COG1396	sequence-specific DNA binding
S101413_RS12580	COG4940	Competence protein ComGF
S101413_RS12590	COG4970	Tfp pilus assembly protein FimT
S101413_RS12595	COG4537	Required for transformation and DNA binding
S101413_RS12605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
S101413_RS12615	COG1253	flavin adenine dinucleotide binding
S101413_RS12630	COG1393	Belongs to the ArsC family
S101413_RS12640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS12650	COG0011	TIGRFAM Protein of
S101413_RS12660	COG2866	Carboxypeptidase
S101413_RS12665	COG1940	carbohydrate kinase activity
S101413_RS12670	COG4483	Protein conserved in bacteria
S101413_RS12685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
S101413_RS12700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101413_RS12705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101413_RS12710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
S101413_RS12715	COG0581	inorganic phosphate transmembrane transporter activity
S101413_RS12720	COG0573	inorganic phosphate transmembrane transporter activity
S101413_RS12725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
S101413_RS12730	COG0768	penicillin binding
S101413_RS12735	COG0477	Major facilitator Superfamily
S101413_RS12740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
S101413_RS12745	COG2839	Protein conserved in bacteria
S101413_RS12750	COG5521	maltodextrose utilization protein MalA
S101413_RS12755	COG1388	LysM domain
S101413_RS12765	COG4709	membrane
S101413_RS12770	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
S101413_RS12775	COG0735	belongs to the Fur family
S101413_RS12780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS12810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
S101413_RS12820	COG2010	Cytochrome c
S101413_RS12825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
S101413_RS12830	COG0358	DNA primase activity
S101413_RS12845	COG0517	IMP dehydrogenase activity
S101413_RS12850	COG0751	glycine-tRNA ligase activity
S101413_RS12870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
S101413_RS12875	COG0295	cytidine deaminase activity
S101413_RS12880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
S101413_RS12890	COG1480	7TM receptor with intracellular HD hydrolase
S101413_RS12895	COG1702	phosphate starvation-inducible protein PhoH
S101413_RS12915	COG4864	UPF0365 protein
S101413_RS12920	COG1030	water channel activity
S101413_RS12925	COG1610	YqeY-like protein
S101413_RS12935	COG1283	sodium-dependent phosphate transmembrane transporter activity
S101413_RS12940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
S101413_RS12945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
S101413_RS12975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
S101413_RS12990	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101413_RS13005	COG1466	dna polymerase III delta subunit
S101413_RS13020	COG2333	competence protein COMEC
S101413_RS13020	COG0658	competence protein
S101413_RS13025	COG2131	deaminase
S101413_RS13030	COG1596	polysaccharide export
S101413_RS13030	COG1555	photosystem II stabilization
S101413_RS13035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
S101413_RS13045	COG0799	negative regulation of ribosome biogenesis
S101413_RS13050	COG1713	HD superfamily hydrolase involved in NAD metabolism
S101413_RS13060	COG1534	Rna-binding protein
S101413_RS13065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
S101413_RS13070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
S101413_RS13075	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
S101413_RS13085	COG2755	lipolytic protein G-D-S-L family
S101413_RS13095	COG0398	Pfam SNARE associated Golgi protein
S101413_RS13130	COG5444	nuclease activity
S101413_RS13135	COG4282	regulation of fungal-type cell wall biogenesis
S101413_RS13150	COG3708	Transcriptional regulator
S101413_RS13150	COG2207	Transcriptional regulator
S101413_RS13155	COG0583	DNA-binding transcription factor activity
S101413_RS13170	COG0642	Histidine kinase
S101413_RS13170	COG5002	protein histidine kinase activity
S101413_RS13175	COG0745	RESPONSE REGULATOR receiver
S101413_RS13180	COG2311	Membrane
S101413_RS13185	COG0454	-acetyltransferase
S101413_RS13190	COG0563	adenylate kinase activity
S101413_RS13200	COG2814	Major facilitator Superfamily
S101413_RS13215	COG2318	DinB family
S101413_RS13225	COG0561	phosphatase activity
S101413_RS13230	COG0561	phosphatase activity
S101413_RS13240	COG1482	cell wall glycoprotein biosynthetic process
S101413_RS13245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS13245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101413_RS13245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
S101413_RS13250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS13250	COG3711	transcriptional antiterminator
S101413_RS13260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
S101413_RS13265	COG0583	DNA-binding transcription factor activity
S101413_RS13270	COG2814	Major facilitator Superfamily
S101413_RS13275	COG2124	cytochrome p450
S101413_RS13275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101413_RS13280	COG1309	transcriptional regulator
S101413_RS13285	COG2226	methyltransferase
S101413_RS13300	COG2116	formate transmembrane transporter activity
S101413_RS13305	COG5609	conserved protein (DUF2294)
S101413_RS13310	COG3383	formate dehydrogenase (NAD+) activity
S101413_RS13315	COG2427	Protein of unknown function (DUF1641)
S101413_RS13325	COG0626	cystathionine gamma-synthase activity
S101413_RS13330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101413_RS13355	COG0768	penicillin binding
S101413_RS13370	COG0826	peptidase U32
S101413_RS13375	COG0826	peptidase U32
S101413_RS13380	COG4122	O-methyltransferase activity
S101413_RS13385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
S101413_RS13410	COG0628	permease
S101413_RS13415	COG1126	abc transporter atp-binding protein
S101413_RS13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101413_RS13425	COG0765	amino acid transport
S101413_RS13450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
S101413_RS13455	COG0457	Tetratricopeptide repeat
S101413_RS13465	COG1104	cysteine desulfurase activity
S101413_RS13470	COG1959	2 iron, 2 sulfur cluster binding
S101413_RS13475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
S101413_RS13480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
S101413_RS13515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
S101413_RS13530	COG5416	Lipopolysaccharide assembly protein A domain
S101413_RS13535	COG0490	domain, Protein
S101413_RS13540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101413_RS13540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
S101413_RS13555	COG2323	membrane
S101413_RS13565	COG1862	Preprotein translocase
S101413_RS13610	COG1388	LysM domain
S101413_RS13620	COG0157	Belongs to the NadC ModD family
S101413_RS13640	COG0077	Prephenate dehydratase
S101413_RS13655	COG3290	protein histidine kinase activity
S101413_RS13660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
S101413_RS13680	COG0739	heme binding
S101413_RS13685	COG2894	cell division
S101413_RS13695	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
S101413_RS13705	COG1077	Cell shape determining protein MreB Mrl
S101413_RS13725	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS13725	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS13730	COG4824	toxin secretion phage lysis holin
S101413_RS13750	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS13900	COG1396	sequence-specific DNA binding
S101413_RS13930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
S101413_RS13935	COG0285	dihydrofolate synthase activity
S101413_RS13940	COG0525	valine-tRNA ligase activity
S101413_RS13950	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
S101413_RS13965	COG0113	porphobilinogen synthase activity
S101413_RS13980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
S101413_RS14000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
S101413_RS14020	COG0457	Tetratricopeptide repeat
S101413_RS14020	COG1477	protein flavinylation
S101413_RS14035	COG0473	3-isopropylmalate dehydrogenase activity
S101413_RS14050	COG0440	acetolactate synthase activity
S101413_RS14055	COG0028	Belongs to the TPP enzyme family
S101413_RS14110	COG0622	Phosphoesterase
S101413_RS14115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
S101413_RS14125	COG5401	PFAM Sporulation and spore germination
S101413_RS14140	COG2197	response regulator
S101413_RS14145	COG0824	Thioesterase
S101413_RS14150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
S101413_RS14155	COG1053	succinate dehydrogenase
S101413_RS14160	COG2009	succinate dehydrogenase
S101413_RS14165	COG1719	4-vinyl reductase, 4VR
S101413_RS14170	COG0527	aspartate kinase activity
S101413_RS14185	COG3118	belongs to the thioredoxin family
S101413_RS14190	COG3534	alpha-L-arabinofuranosidase
S101413_RS14200	COG2086	electron transfer activity
S101413_RS14205	COG1024	Enoyl-CoA hydratase
S101413_RS14210	COG1309	transcriptional regulator
S101413_RS14215	COG0318	PFAM AMP-dependent synthetase and ligase
S101413_RS14225	COG3766	membrane
S101413_RS14235	COG1796	DNA polymerase
S101413_RS14235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101413_RS14240	COG1286	toxin biosynthetic process
S101413_RS14260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
S101413_RS14265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
S101413_RS14275	COG3835	regulator
S101413_RS14285	COG0247	lactate metabolic process
S101413_RS14290	COG1966	Carbon starvation protein
S101413_RS14295	COG3534	alpha-L-arabinofuranosidase
S101413_RS14300	COG0395	ABC-type sugar transport system, permease component
S101413_RS14305	COG1175	transmembrane transport
S101413_RS14310	COG1653	transport
S101413_RS14320	COG0647	UMP catabolic process
S101413_RS14325	COG0235	Class ii aldolase
S101413_RS14330	COG1069	ribulokinase activity
S101413_RS14335	COG2160	L-arabinose isomerase activity
S101413_RS14340	COG3507	Belongs to the glycosyl hydrolase 43 family
S101413_RS14345	COG1363	Peptidase, m42
S101413_RS14355	COG3326	Membrane
S101413_RS14370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
S101413_RS14375	COG1346	cytolysis
S101413_RS14380	COG1380	Effector of murein hydrolase LrgA
S101413_RS14385	COG3279	Response regulator of the LytR AlgR family
S101413_RS14390	COG3275	phosphorelay sensor kinase activity
S101413_RS14395	COG1011	Hydrolase
S101413_RS14410	COG0398	Pfam SNARE associated Golgi protein
S101413_RS14415	COG1484	DNA-dependent DNA replication
S101413_RS14435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101413_RS14440	COG1733	regulation of RNA biosynthetic process
S101413_RS14445	COG2814	Major facilitator Superfamily
S101413_RS14450	COG0656	L-ascorbic acid biosynthetic process
S101413_RS14455	COG0237	dephospho-CoA kinase activity
S101413_RS14460	COG1971	Probably functions as a manganese efflux pump
S101413_RS14465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
S101413_RS14470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101413_RS14470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
S101413_RS14475	COG5002	protein histidine kinase activity
S101413_RS14480	COG0745	RESPONSE REGULATOR receiver
S101413_RS14490	COG0538	isocitrate dehydrogenase activity
S101413_RS14495	COG0372	Belongs to the citrate synthase family
S101413_RS14500	COG0457	Tetratricopeptide repeat
S101413_RS14530	COG0628	permease
S101413_RS14535	COG3030	protein affecting phage T7 exclusion by the F plasmid
S101413_RS14540	COG0469	pyruvate kinase activity
S101413_RS14560	COG0281	malic enzyme
S101413_RS14565	COG0587	DNA-directed DNA polymerase activity
S101413_RS14585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
S101413_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS14620	COG0521	Mo-molybdopterin cofactor biosynthetic process
S101413_RS14635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
S101413_RS14650	COG1714	RDD family
S101413_RS14655	COG0616	signal peptide processing
S101413_RS14660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
S101413_RS14665	COG1574	metal-dependent hydrolase with the TIM-barrel fold
S101413_RS14670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101413_RS14685	COG1104	cysteine desulfurase activity
S101413_RS14700	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
S101413_RS14705	COG1309	transcriptional regulator
S101413_RS14710	COG1956	GAF domain-containing protein
S101413_RS14715	COG2203	Gaf domain
S101413_RS14715	COG2199	diguanylate cyclase activity
S101413_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS14735	COG4282	regulation of fungal-type cell wall biogenesis
S101413_RS14780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
S101413_RS14780	COG1017	nitric oxide dioxygenase activity
S101413_RS14795	COG0693	protein deglycase activity
S101413_RS14810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
S101413_RS14815	COG1378	Sugar-specific transcriptional regulator TrmB
S101413_RS14840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
S101413_RS14845	COG0454	-acetyltransferase
S101413_RS14850	COG0517	IMP dehydrogenase activity
S101413_RS14855	COG0123	including yeast histone deacetylase and acetoin utilization protein
S101413_RS14860	COG1360	Flagellar Motor Protein
S101413_RS14865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
S101413_RS14870	COG1609	Transcriptional regulator
S101413_RS14875	COG1605	Chorismate mutase
S101413_RS14875	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
S101413_RS14880	COG3118	belongs to the thioredoxin family
S101413_RS14885	COG4980	gas vesicle protein
S101413_RS14890	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
S101413_RS14900	COG1674	ftsk spoiiie
S101413_RS14905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
S101413_RS14915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
S101413_RS14935	COG1363	Peptidase, m42
S101413_RS14940	COG5584	Small secreted protein
S101413_RS14945	COG0281	malic enzyme
S101413_RS14950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
S101413_RS14965	COG0510	thiamine kinase activity
S101413_RS14970	COG1597	lipid kinase activity
S101413_RS14980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
S101413_RS14985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
S101413_RS14990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101413_RS14995	COG2252	PERMEase
S101413_RS15000	COG4473	ABC transporter
S101413_RS15005	COG1131	(ABC) transporter
S101413_RS15010	COG1349	DNA-binding transcription factor activity
S101413_RS15030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
S101413_RS15055	COG1175	transmembrane transport
S101413_RS15060	COG0395	ABC-type sugar transport system, permease component
S101413_RS15065	COG1486	melibiose metabolic process
S101413_RS15075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
S101413_RS15090	COG2202	Pas domain
S101413_RS15090	COG1366	Belongs to the anti-sigma-factor antagonist family
S101413_RS15095	COG2814	Major facilitator Superfamily
S101413_RS15100	COG5522	Integral membrane protein (intg_mem_TP0381)
S101413_RS15105	COG0577	efflux transmembrane transporter activity
S101413_RS15110	COG1136	(ABC) transporter
S101413_RS15115	COG2205	protein histidine kinase activity
S101413_RS15120	COG0745	RESPONSE REGULATOR receiver
S101413_RS15125	COG0577	efflux transmembrane transporter activity
S101413_RS15130	COG1136	(ABC) transporter
S101413_RS15150	COG1131	(ABC) transporter
S101413_RS15155	COG1725	Transcriptional regulator
S101413_RS15175	COG1242	4 iron, 4 sulfur cluster binding
S101413_RS15180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
S101413_RS15190	COG0584	glycerophosphoryl diester phosphodiesterase
S101413_RS15200	COG2267	carboxylic ester hydrolase activity
S101413_RS15205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
S101413_RS15210	COG1113	amino acid transport
S101413_RS15215	COG0367	asparagine synthase
S101413_RS15235	COG1506	peptidase
S101413_RS15240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
S101413_RS15245	COG1116	anion transmembrane transporter activity
S101413_RS15250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
S101413_RS15255	COG0494	nUDIX hydrolase
S101413_RS15260	COG4824	toxin secretion phage lysis holin
S101413_RS15265	COG0783	Belongs to the Dps family
S101413_RS15290	COG0288	reversible hydration of carbon dioxide
S101413_RS15300	COG1271	oxidase subunit
S101413_RS15305	COG1294	oxidase, subunit
S101413_RS15315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
S101413_RS15325	COG1121	(ABC) transporter
S101413_RS15330	COG0803	Belongs to the bacterial solute-binding protein 9 family
S101413_RS15335	COG4948	Mandelate Racemase Muconate Lactonizing
S101413_RS15345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
S101413_RS15350	COG0596	Alpha beta hydrolase
S101413_RS15360	COG1169	isochorismate synthase
S101413_RS15365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
S101413_RS15370	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
S101413_RS15495	COG3859	Proton-coupled thiamine transporter YuaJ
S101413_RS15500	COG2268	Band 7 protein
S101413_RS15520	COG1454	alcohol dehydrogenase
S101413_RS15525	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS15530	COG1510	regulation of RNA biosynthetic process
S101413_RS15540	COG0569	domain protein
S101413_RS15545	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101413_RS15570	COG0457	Tetratricopeptide repeat
S101413_RS15605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
S101413_RS15625	COG0673	inositol 2-dehydrogenase activity
S101413_RS15630	COG0693	protein deglycase activity
S101413_RS15635	COG0840	transmembrane signaling receptor activity
S101413_RS15645	COG0840	transmembrane signaling receptor activity
S101413_RS15650	COG0840	transmembrane signaling receptor activity
S101413_RS15665	COG2070	2-Nitropropane dioxygenase
S101413_RS15670	COG0432	Pfam Uncharacterised protein family UPF0047
S101413_RS15675	COG0366	Alpha amylase catalytic
S101413_RS15680	COG1253	flavin adenine dinucleotide binding
S101413_RS15685	COG2738	Putative neutral zinc metallopeptidase
S101413_RS15700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
S101413_RS15730	COG1335	isochorismatase
S101413_RS15745	COG2155	Conserved Protein
S101413_RS15755	COG1098	S1 RNA binding domain
S101413_RS15760	COG0436	Aminotransferase
S101413_RS15765	COG1522	sequence-specific DNA binding
S101413_RS15770	COG2267	carboxylic ester hydrolase activity
S101413_RS15780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
S101413_RS15785	COG2205	protein histidine kinase activity
S101413_RS15795	COG5018	Exonuclease
S101413_RS15800	COG2814	Major facilitator Superfamily
S101413_RS15805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101413_RS15810	COG3011	Protein conserved in bacteria
S101413_RS15820	COG3290	protein histidine kinase activity
S101413_RS15825	COG4565	transcriptional regulatory protein
S101413_RS15830	COG1744	ABC transporter substrate-binding protein PnrA-like
S101413_RS15835	COG3845	ABC transporter
S101413_RS15840	COG4603	Belongs to the binding-protein-dependent transport system permease family
S101413_RS15845	COG1079	Belongs to the binding-protein-dependent transport system permease family
S101413_RS15855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
S101413_RS15855	COG2111	Na H antiporter
S101413_RS15865	COG1006	Multisubunit Na H antiporter MnhC subunit
S101413_RS15870	COG0651	ATP synthesis coupled electron transport
S101413_RS15875	COG1863	multisubunit Na H antiporter MnhE subunit
S101413_RS15880	COG2212	antiporter activity
S101413_RS15885	COG1320	monovalent cation:proton antiporter activity
S101413_RS15890	COG2050	protein possibly involved in aromatic compounds catabolism
S101413_RS15895	COG2197	response regulator
S101413_RS15905	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101413_RS15915	COG1335	isochorismatase
S101413_RS15920	COG5506	Protein of unknown function (DUF1694)
S101413_RS15945	COG1418	mRNA catabolic process
S101413_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS15960	COG1511	domain protein
S101413_RS15965	COG0433	COG0433 Predicted ATPase
S101413_RS15965	COG1674	ftsk spoiiie
S101413_RS15970	COG4499	WXG100 protein secretion system (Wss), protein YukC
S101413_RS15975	COG5417	Belongs to the EsaB family
S101413_RS15980	COG4842	Belongs to the WXG100 family
S101413_RS15985	COG2508	Transcriptional regulator
S101413_RS15985	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
S101413_RS15990	COG0686	Belongs to the AlaDH PNT family
S101413_RS15995	COG5634	Uncharacterized conserved protein (DUF2278)
S101413_RS16000	COG3251	PFAM MbtH domain protein
S101413_RS16005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
S101413_RS16010	COG1535	isochorismatase
S101413_RS16010	COG3433	isochorismatase activity
S101413_RS16015	COG1021	2,3-dihydroxybenzoate-AMP ligase
S101413_RS16020	COG1169	isochorismate synthase
S101413_RS16025	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS16030	COG2819	hydrolase of the alpha beta superfamily
S101413_RS16035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
S101413_RS16045	COG2056	Na+-H+ antiporter family
S101413_RS16060	COG3584	3D domain protein
S101413_RS16070	COG1252	NADH dehydrogenase
S101413_RS16120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
S101413_RS16125	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
S101413_RS16230	COG0582	viral genome integration into host DNA
S101413_RS16245	COG0316	Belongs to the HesB IscA family
S101413_RS16255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101413_RS16270	COG4837	Protein of unknown function (DUF1462)
S101413_RS16290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
S101413_RS16305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
S101413_RS16310	COG0647	UMP catabolic process
S101413_RS16315	COG2445	Protein of unknown function DUF86
S101413_RS16320	COG4470	Protein conserved in bacteria
S101413_RS16335	COG0739	heme binding
S101413_RS16345	COG0737	Belongs to the 5'-nucleotidase family
S101413_RS16350	COG0730	response to heat
S101413_RS16370	COG2508	Transcriptional regulator
S101413_RS16400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
S101413_RS16405	COG2356	endonuclease I
S101413_RS16410	COG3842	ATPase activity
S101413_RS16415	COG2188	Transcriptional regulator
S101413_RS16420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101413_RS16425	COG0395	ABC-type sugar transport system, permease component
S101413_RS16430	COG1175	transmembrane transport
S101413_RS16440	COG2222	sugar isomerase
S101413_RS16470	COG0322	excinuclease ABC activity
S101413_RS16495	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS16500	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS16500	COG1388	LysM domain
S101413_RS16500	COG5632	N-Acetylmuramoyl-L-alanine amidase
S101413_RS16530	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS16705	COG1396	sequence-specific DNA binding
S101413_RS16715	COG4974	Belongs to the 'phage' integrase family
S101413_RS16725	COG0822	iron-sulfur transferase activity
S101413_RS16730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
S101413_RS16735	COG0719	Fe-S assembly protein
S101413_RS16740	COG0396	ATPase activity
S101413_RS16750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
S101413_RS16760	COG2011	ABC-type metal ion transport system permease component
S101413_RS16780	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
S101413_RS16795	COG1393	Belongs to the ArsC family
S101413_RS16830	COG5577	PFAM Coat F domain
S101413_RS16870	COG1120	ATPase activity
S101413_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS16890	COG0783	Belongs to the Dps family
S101413_RS16895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101413_RS16905	COG0745	RESPONSE REGULATOR receiver
S101413_RS16910	COG2205	protein histidine kinase activity
S101413_RS16910	COG2770	Histidine kinase
S101413_RS16920	COG1309	transcriptional regulator
S101413_RS16935	COG0697	spore germination
S101413_RS16940	COG0814	amino acid
S101413_RS16950	COG2197	response regulator
S101413_RS16955	COG4585	Histidine kinase
S101413_RS16960	COG4758	membrane
S101413_RS16965	COG3595	metallopeptidase activity
S101413_RS16970	COG1842	Phage shock protein A
S101413_RS16975	COG4758	membrane
S101413_RS16980	COG2814	Major facilitator Superfamily
S101413_RS16985	COG2096	Adenosyltransferase
S101413_RS16990	COG1120	ATPase activity
S101413_RS16995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS17000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101413_RS17005	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS17010	COG3386	PFAM SMP-30 Gluconolaconase
S101413_RS17015	COG2205	protein histidine kinase activity
S101413_RS17020	COG0745	RESPONSE REGULATOR receiver
S101413_RS17030	COG1191	sigma factor activity
S101413_RS17040	COG2140	Oxalate decarboxylase
S101413_RS17050	COG1120	ATPase activity
S101413_RS17055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS17060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS17070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
S101413_RS17075	COG0531	amino acid
S101413_RS17090	COG1988	membrane-bound metal-dependent
S101413_RS17100	COG1910	domain protein
S101413_RS17105	COG0725	ABC transporter, periplasmic molybdate-binding protein
S101413_RS17110	COG4149	molybdate abc transporter
S101413_RS17115	COG2197	response regulator
S101413_RS17120	COG3850	Histidine kinase
S101413_RS17125	COG1131	(ABC) transporter
S101413_RS17135	COG0842	Transport permease protein
S101413_RS17140	COG0656	L-ascorbic acid biosynthetic process
S101413_RS17165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
S101413_RS17175	COG2860	membrane
S101413_RS17185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
S101413_RS17190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
S101413_RS17200	COG2217	Heavy metal translocating P-type atpase
S101413_RS17205	COG2608	mercury ion transmembrane transporter activity
S101413_RS17210	COG1937	Protein conserved in bacteria
S101413_RS17215	COG0673	inositol 2-dehydrogenase activity
S101413_RS17225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS17230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
S101413_RS17235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS17240	COG1126	abc transporter atp-binding protein
S101413_RS17245	COG0765	amino acid transport
S101413_RS17250	COG0765	amino acid transport
S101413_RS17255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101413_RS17260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
S101413_RS17265	COG0454	-acetyltransferase
S101413_RS17270	COG0583	DNA-binding transcription factor activity
S101413_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS17280	COG2732	(Barnase) inhibitor
S101413_RS17290	COG2732	(Barnase) inhibitor
S101413_RS17310	COG4824	toxin secretion phage lysis holin
S101413_RS17330	COG5434	Belongs to the glycosyl hydrolase 28 family
S101413_RS17335	COG1705	Flagellar rod assembly protein muramidase FlgJ
S101413_RS17335	COG1388	LysM domain
S101413_RS17405	COG1802	Transcriptional regulator
S101413_RS17405	COG4626	Terminase
S101413_RS17435	COG0582	viral genome integration into host DNA
S101413_RS17440	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
S101413_RS17580	COG0557	exoribonuclease II activity
S101413_RS17585	COG1647	Serine aminopeptidase, S33
S101413_RS17590	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
S101413_RS17595	COG1476	TRANSCRIPTIONal
S101413_RS17600	COG1396	sequence-specific DNA binding
S101413_RS17605	COG1396	sequence-specific DNA binding
S101413_RS17610	COG1733	regulation of RNA biosynthetic process
S101413_RS17635	COG1131	(ABC) transporter
S101413_RS17640	COG1174	glycine betaine transport
S101413_RS17645	COG1732	Glycine betaine
S101413_RS17650	COG1174	glycine betaine transport
S101413_RS17655	COG0517	IMP dehydrogenase activity
S101413_RS17655	COG1125	glycine betaine transport
S101413_RS17660	COG1510	regulation of RNA biosynthetic process
S101413_RS17665	COG1174	glycine betaine transport
S101413_RS17670	COG1732	Glycine betaine
S101413_RS17675	COG1174	glycine betaine transport
S101413_RS17685	COG1510	regulation of RNA biosynthetic process
S101413_RS17690	COG2095	MarC family integral membrane protein
S101413_RS17695	COG3064	Membrane
S101413_RS17705	COG0456	acetyltransferase
S101413_RS17735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
S101413_RS17740	COG2390	Transcriptional regulator
S101413_RS17745	COG2814	Major facilitator Superfamily
S101413_RS17750	COG1609	Transcriptional regulator
S101413_RS17755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS17760	COG0583	DNA-binding transcription factor activity
S101413_RS17765	COG0697	spore germination
S101413_RS17775	COG1113	amino acid transport
S101413_RS17780	COG1737	Transcriptional regulator
S101413_RS17785	COG1070	Carbohydrate kinase
S101413_RS17810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101413_RS17815	COG2186	Transcriptional regulator
S101413_RS17820	COG1620	l-lactate permease
S101413_RS17825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
S101413_RS17835	COG5039	Polysaccharide pyruvyl transferase
S101413_RS17840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101413_RS17845	COG0110	maltose O-acetyltransferase activity
S101413_RS17850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
S101413_RS17855	COG2244	polysaccharide biosynthetic process
S101413_RS17860	COG1216	Glycosyl transferase, family 2
S101413_RS17865	COG5039	Polysaccharide pyruvyl transferase
S101413_RS17870	COG1216	Glycosyl transferase, family 2
S101413_RS17880	COG0438	transferase activity, transferring glycosyl groups
S101413_RS17885	COG1215	transferase activity, transferring glycosyl groups
S101413_RS17890	COG0438	transferase activity, transferring glycosyl groups
S101413_RS17895	COG1086	Polysaccharide biosynthesis protein
S101413_RS17900	COG0489	protein tyrosine kinase activity
S101413_RS17905	COG3944	biosynthesis protein
S101413_RS17910	COG1396	sequence-specific DNA binding
S101413_RS17915	COG2272	Belongs to the type-B carboxylesterase lipase family
S101413_RS17925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
S101413_RS17930	COG2364	Membrane
S101413_RS17935	COG0456	acetyltransferase
S101413_RS17940	COG3479	Phenolic acid decarboxylase
S101413_RS17980	COG2223	nitrite transmembrane transporter activity
S101413_RS17985	COG1609	Transcriptional regulator
S101413_RS17995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
S101413_RS18000	COG0366	Alpha amylase catalytic
S101413_RS18005	COG1554	hydrolase, family 65, central catalytic
S101413_RS18010	COG5521	maltodextrose utilization protein MalA
S101413_RS18015	COG3833	ABC-type maltose transport systems, permease component
S101413_RS18020	COG1175	transmembrane transport
S101413_RS18025	COG2182	Extracellular solute-binding protein
S101413_RS18030	COG0366	Alpha amylase catalytic
S101413_RS18035	COG1609	Transcriptional regulator
S101413_RS18045	COG1694	Mazg nucleotide pyrophosphohydrolase
S101413_RS18050	COG0659	secondary active sulfate transmembrane transporter activity
S101413_RS18055	COG0288	reversible hydration of carbon dioxide
S101413_RS18065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
S101413_RS18070	COG4290	ribonuclease
S101413_RS18080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS18090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
S101413_RS18100	COG1051	belongs to the nudix hydrolase family
S101413_RS18105	COG0492	ferredoxin-NADP+ reductase activity
S101413_RS18115	COG0457	Tetratricopeptide repeat
S101413_RS18125	COG0745	RESPONSE REGULATOR receiver
S101413_RS18135	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
S101413_RS18135	COG0140	phosphoribosyl-ATP diphosphatase activity
S101413_RS18160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
S101413_RS18175	COG4990	cell redox homeostasis
S101413_RS18180	COG0110	maltose O-acetyltransferase activity
S101413_RS18200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
S101413_RS18210	COG2188	Transcriptional regulator
S101413_RS18215	COG1309	transcriptional regulator
S101413_RS18225	COG1950	PFAM Membrane protein of
S101413_RS18230	COG1983	PspC domain protein
S101413_RS18235	COG3595	metallopeptidase activity
S101413_RS18250	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
S101413_RS18260	COG4897	Protein conserved in bacteria
S101413_RS18270	COG1309	transcriptional regulator
S101413_RS18275	COG2814	Major facilitator Superfamily
S101413_RS18290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101413_RS18300	COG3409	Peptidoglycan-binding domain 1 protein
S101413_RS18300	COG0793	Belongs to the peptidase S41A family
S101413_RS18305	COG3420	alginic acid biosynthetic process
S101413_RS18310	COG2177	Part of the ABC transporter FtsEX involved in
S101413_RS18325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS18340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
S101413_RS18355	COG1516	flagellar protein fliS
S101413_RS18360	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
S101413_RS18365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101413_RS18385	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
S101413_RS18390	COG1256	bacterial-type flagellum assembly
S101413_RS18390	COG4786	Flagellar basal body rod
S101413_RS18395	COG3418	PFAM FlgN family protein
S101413_RS18400	COG2747	anti-sigma28 factor FlgM
S101413_RS18410	COG1040	competence protein
S101413_RS18420	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
S101413_RS18425	COG1307	EDD domain protein, DegV family
S101413_RS18430	COG2197	response regulator
S101413_RS18435	COG4585	Histidine kinase
S101413_RS18440	COG1739	Uncharacterized protein family UPF0029
S101413_RS18445	COG1316	TRANSCRIPTIONal
S101413_RS18450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
S101413_RS18460	COG1215	transferase activity, transferring glycosyl groups
S101413_RS18465	COG3206	protein involved in exopolysaccharide biosynthesis
S101413_RS18470	COG3307	-O-antigen
S101413_RS18475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101413_RS18480	COG0438	transferase activity, transferring glycosyl groups
S101413_RS18480	COG0297	glycogen (starch) synthase activity
S101413_RS18485	COG2244	polysaccharide biosynthetic process
S101413_RS18495	COG0860	N-Acetylmuramoyl-L-alanine amidase
S101413_RS18495	COG2247	cell wall binding repeat
S101413_RS18500	COG2385	sporulation resulting in formation of a cellular spore
S101413_RS18500	COG2247	cell wall binding repeat
S101413_RS18510	COG1316	TRANSCRIPTIONal
S101413_RS18515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
S101413_RS18520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
S101413_RS18525	COG1134	teichoic acid transport
S101413_RS18530	COG1682	transport, permease protein
S101413_RS18535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101413_RS18540	COG0438	transferase activity, transferring glycosyl groups
S101413_RS18545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
S101413_RS18550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
S101413_RS18555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101413_RS18560	COG4193	domain, Protein
S101413_RS18565	COG1482	cell wall glycoprotein biosynthetic process
S101413_RS18570	COG0697	spore germination
S101413_RS18590	COG2814	Major facilitator Superfamily
S101413_RS18595	COG1316	TRANSCRIPTIONal
S101413_RS18600	COG0561	phosphatase activity
S101413_RS18610	COG0791	NLP P60 protein
S101413_RS18620	COG2843	Capsule synthesis protein
S101413_RS18630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
S101413_RS18640	COG0697	spore germination
S101413_RS18645	COG0814	amino acid
S101413_RS18655	COG1609	Transcriptional regulator
S101413_RS18660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
S101413_RS18670	COG1129	ABC transporter
S101413_RS18680	COG1879	ABC-type sugar transport system periplasmic component
S101413_RS18685	COG3103	Sh3 type 3 domain protein
S101413_RS18690	COG2249	NAD(P)H dehydrogenase (quinone) activity
S101413_RS18695	COG3527	Alpha-acetolactate decarboxylase
S101413_RS18700	COG0028	Belongs to the TPP enzyme family
S101413_RS18705	COG0583	DNA-binding transcription factor activity
S101413_RS18710	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101413_RS18725	COG5337	Spore coat protein CotH
S101413_RS18735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
S101413_RS18745	COG0405	Gamma-glutamyltransferase
S101413_RS18750	COG1522	sequence-specific DNA binding
S101413_RS18755	COG2059	Chromate
S101413_RS18760	COG2059	Chromate
S101413_RS18770	COG0655	NAD(P)H dehydrogenase (quinone) activity
S101413_RS18775	COG0583	DNA-binding transcription factor activity
S101413_RS18820	COG3878	Protein conserved in bacteria
S101413_RS18825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
S101413_RS18830	COG4464	protein tyrosine phosphatase activity
S101413_RS18835	COG0489	protein tyrosine kinase activity
S101413_RS18840	COG3944	biosynthesis protein
S101413_RS18855	COG4715	Zinc finger, swim domain protein
S101413_RS18865	COG0561	phosphatase activity
S101413_RS18870	COG1349	DNA-binding transcription factor activity
S101413_RS18875	COG0629	single-stranded DNA binding
S101413_RS18900	COG0457	Tetratricopeptide repeat
S101413_RS18905	COG4786	Flagellar basal body rod
S101413_RS18910	COG4786	Flagellar basal body rod
S101413_RS18915	COG1077	Cell shape determining protein MreB Mrl
S101413_RS18920	COG1609	Transcriptional regulator
S101413_RS18925	COG1846	Transcriptional regulator
S101413_RS18930	COG2814	Major facilitator Superfamily
S101413_RS18935	COG1953	Uracil, thiamine, allantoin
S101413_RS18940	COG0477	Major facilitator Superfamily
S101413_RS18945	COG1335	isochorismatase
S101413_RS18950	COG0004	ammonium transporteR
S101413_RS18955	COG0347	Belongs to the P(II) protein family
S101413_RS18960	COG0772	Belongs to the SEDS family
S101413_RS18965	COG0671	phosphoesterase, PA-phosphatase related
S101413_RS18975	COG0739	heme binding
S101413_RS18980	COG1247	-acetyltransferase
S101413_RS19015	COG1959	2 iron, 2 sulfur cluster binding
S101413_RS19030	COG0831	urea catabolic process
S101413_RS19045	COG0457	Tetratricopeptide repeat
S101413_RS19055	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
S101413_RS19060	COG2304	oxidoreductase activity
S101413_RS19065	COG2304	oxidoreductase activity
S101413_RS19070	COG2385	sporulation resulting in formation of a cellular spore
S101413_RS19075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101413_RS19085	COG4836	Membrane
S101413_RS19155	COG0698	ribose 5-phosphate isomerase
S101413_RS19160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
S101413_RS19170	COG0009	L-threonylcarbamoyladenylate synthase
S101413_RS19175	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
S101413_RS19195	COG2890	protein-(glutamine-N5) methyltransferase activity
S101413_RS19200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
S101413_RS19205	COG0346	lactoylglutathione lyase activity
S101413_RS19210	COG0789	Transcriptional regulator
S101413_RS19215	COG0679	Auxin Efflux Carrier
S101413_RS19220	COG0281	malic enzyme
S101413_RS19235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
S101413_RS19240	COG1494	fructose-1,6-bisphosphatase
S101413_RS19245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
S101413_RS19255	COG0191	fructose-bisphosphate aldolase activity
S101413_RS19260	COG2204	response regulator
S101413_RS19265	COG4821	SIS domain
S101413_RS19280	COG2181	nitrate reductase activity
S101413_RS19280	COG0247	lactate metabolic process
S101413_RS19285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101413_RS19300	COG1132	(ABC) transporter
S101413_RS19305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
S101413_RS19315	COG2181	nitrate reductase activity
S101413_RS19320	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
S101413_RS19325	COG1140	nitrate reductase beta subunit
S101413_RS19335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101413_RS19345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
S101413_RS19350	COG2223	nitrite transmembrane transporter activity
S101413_RS19360	COG4506	Protein conserved in bacteria
S101413_RS19375	COG0010	Belongs to the arginase family
S101413_RS19380	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
S101413_RS19385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
S101413_RS19400	COG1994	Peptidase M50
S101413_RS19405	COG1942	4-Oxalocrotonate Tautomerase
S101413_RS19410	COG1846	Transcriptional regulator
S101413_RS19420	COG0531	amino acid
S101413_RS19425	COG3465	dGTPase activity
S101413_RS19430	COG1078	dGTPase activity
S101413_RS19445	COG1695	Transcriptional regulator
S101413_RS19455	COG1131	(ABC) transporter
S101413_RS19460	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
S101413_RS19490	COG0583	DNA-binding transcription factor activity
S101413_RS19495	COG2855	membrane
S101413_RS19500	COG0280	phosphate acetyltransferase
S101413_RS19515	COG0436	Aminotransferase
S101413_RS19545	COG2814	Major facilitator Superfamily
S101413_RS19550	COG2814	Major facilitator Superfamily
S101413_RS19570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
S101413_RS19575	COG2205	protein histidine kinase activity
S101413_RS19580	COG0745	RESPONSE REGULATOR receiver
S101413_RS19595	COG1131	(ABC) transporter
S101413_RS19600	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
S101413_RS19605	COG1091	dTDP-4-dehydrorhamnose reductase activity
S101413_RS19610	COG1088	dTDP-glucose 4,6-dehydratase activity
S101413_RS19615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
S101413_RS19620	COG3980	spore coat polysaccharide biosynthesis protein
S101413_RS19630	COG2089	acid synthase
S101413_RS19635	COG0456	acetyltransferase
S101413_RS19640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
S101413_RS19645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
S101413_RS19650	COG0463	Glycosyl transferase, family 2
S101413_RS19660	COG2363	Small membrane protein
S101413_RS19665	COG2233	PERMEase
S101413_RS19680	COG1216	Glycosyl transferase, family 2
S101413_RS19695	COG1695	Transcriptional regulator
S101413_RS19700	COG0351	phosphomethylpyrimidine kinase
S101413_RS19710	COG1621	beta-fructofuranosidase activity
S101413_RS19715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
S101413_RS19715	COG1263	PTS System
S101413_RS19720	COG3711	transcriptional antiterminator
S101413_RS19730	COG1404	Belongs to the peptidase S8 family
S101413_RS19735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
S101413_RS19740	COG0778	Nitroreductase
S101413_RS19745	COG0772	Belongs to the SEDS family
S101413_RS19750	COG0454	-acetyltransferase
S101413_RS19770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
S101413_RS19775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
S101413_RS19780	COG2261	transglycosylase associated protein
S101413_RS19785	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
S101413_RS19790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
S101413_RS19795	COG2246	polysaccharide biosynthetic process
S101413_RS19800	COG1309	transcriptional regulator
S101413_RS19820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
S101413_RS19825	COG2837	iron assimilation
S101413_RS19830	COG2822	iron ion transport
S101413_RS19845	COG0583	DNA-binding transcription factor activity
S101413_RS19855	COG1346	cytolysis
S101413_RS19890	COG4895	conserved protein (DUF2196)
S101413_RS19900	COG5504	Zn-dependent protease
S101413_RS19905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
S101413_RS19910	COG0346	lactoylglutathione lyase activity
S101413_RS19915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS19920	COG1404	Belongs to the peptidase S8 family
S101413_RS19925	COG1442	glycosyl transferase family 8
S101413_RS19930	COG2357	RelA SpoT domain protein
S101413_RS19935	COG1575	Belongs to the MenA family. Type 1 subfamily
S101413_RS19955	COG1696	Membrane protein involved in D-alanine export
S101413_RS19970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
S101413_RS19975	COG1486	melibiose metabolic process
S101413_RS19980	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101413_RS19985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS19990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS19995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
S101413_RS19995	COG3711	transcriptional antiterminator
S101413_RS20010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS20015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
S101413_RS20025	COG0640	Transcriptional regulator
S101413_RS20030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
S101413_RS20035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS20040	COG1447	Phosphotransferase system cellobiose-specific component IIA
S101413_RS20045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
S101413_RS20055	COG1940	carbohydrate kinase activity
S101413_RS20060	COG1482	cell wall glycoprotein biosynthetic process
S101413_RS20070	COG0753	catalase activity
S101413_RS20075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
S101413_RS20080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
S101413_RS20085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
S101413_RS20090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
S101413_RS20095	COG4988	ABC transporter
S101413_RS20110	COG3493	citrate carrier protein
S101413_RS20115	COG0726	polysaccharide deacetylase
S101413_RS20130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS20140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
S101413_RS20150	COG4894	glucomannan catabolic process
S101413_RS20155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
S101413_RS20160	COG0500	methyltransferase
S101413_RS20165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101413_RS20180	COG0693	protein deglycase activity
S101413_RS20180	COG0753	catalase activity
S101413_RS20185	COG2851	Citrate transporter
S101413_RS20190	COG2273	Hydrolase Family 16
S101413_RS20200	COG2270	Major facilitator Superfamily
S101413_RS20205	COG0513	Belongs to the DEAD box helicase family
S101413_RS20295	COG3209	COG3209 Rhs family protein
S101413_RS20305	COG0697	spore germination
S101413_RS20310	COG0589	response to stress
S101413_RS20320	COG0494	nUDIX hydrolase
S101413_RS20325	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
S101413_RS20330	COG3507	Belongs to the glycosyl hydrolase 43 family
S101413_RS20355	COG0010	Belongs to the arginase family
S101413_RS20360	COG0833	amino acid
S101413_RS20365	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
S101413_RS20370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
S101413_RS20380	COG2390	Transcriptional regulator
S101413_RS20420	COG0561	phosphatase activity
S101413_RS20450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
S101413_RS20455	COG5294	Protein conserved in bacteria
S101413_RS20460	COG0577	efflux transmembrane transporter activity
S101413_RS20465	COG1136	(ABC) transporter
S101413_RS20470	COG2205	protein histidine kinase activity
S101413_RS20475	COG0745	RESPONSE REGULATOR receiver
S101413_RS20490	COG1082	Xylose isomerase domain protein TIM barrel
S101413_RS20500	COG2814	Major facilitator Superfamily
S101413_RS20530	COG1349	DNA-binding transcription factor activity
S101413_RS20535	COG0667	Aldo Keto reductase
S101413_RS20540	COG2814	Major facilitator Superfamily
S101413_RS20555	COG1028	Short-chain dehydrogenase reductase Sdr
S101413_RS20560	COG2197	response regulator
S101413_RS20565	COG4585	Histidine kinase
S101413_RS20570	COG3239	Fatty acid desaturase
S101413_RS20575	COG1309	transcriptional regulator
S101413_RS20580	COG1012	belongs to the aldehyde dehydrogenase family
S101413_RS20595	COG0640	Transcriptional regulator
S101413_RS20600	COG2814	Major facilitator Superfamily
S101413_RS20605	COG1714	RDD family
S101413_RS20615	COG0450	alkyl hydroperoxide reductase
S101413_RS20620	COG3634	alkyl hydroperoxide reductase activity
S101413_RS20625	COG3177	Filamentation induced by cAMP protein fic
S101413_RS20630	COG1113	amino acid transport
S101413_RS20640	COG2080	2 iron, 2 sulfur cluster binding
S101413_RS20655	COG2068	MobA-Related Protein
S101413_RS20680	COG1192	Involved in chromosome partitioning
S101413_RS20720	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
S101413_RS20725	COG0667	Aldo Keto reductase
S101413_RS20730	COG0456	acetyltransferase
S101413_RS20740	COG0010	Belongs to the arginase family
S101413_RS20745	COG0833	amino acid
S101413_RS20750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
S101413_RS20760	COG0640	Transcriptional regulator
S101413_RS20765	COG3829	transcription factor binding
S101413_RS20775	COG0488	(ABC) transporter
S101413_RS20790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
S101413_RS20800	COG0745	RESPONSE REGULATOR receiver
S101413_RS20810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
S101413_RS20815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
S101413_RS20820	COG4853	Protein conserved in bacteria
S101413_RS20825	COG4863	YycH protein
S101413_RS20830	COG5002	protein histidine kinase activity
S101413_RS20870	COG0346	lactoylglutathione lyase activity
S101413_RS20875	COG0305	Participates in initiation and elongation during chromosome replication
S101413_RS20890	COG3093	addiction module antidote protein HigA
S101413_RS20900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
S101413_RS20905	COG0297	glycogen (starch) synthase activity
S101413_RS20915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
S101413_RS20920	COG0438	transferase activity, transferring glycosyl groups
S101413_RS20940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
S101413_RS20955	COG5577	PFAM Coat F domain
S101413_RS20960	COG1733	regulation of RNA biosynthetic process
S101413_RS20970	COG0697	spore germination
S101413_RS20975	COG1621	beta-fructofuranosidase activity
S101413_RS20980	COG1621	beta-fructofuranosidase activity
S101413_RS20990	COG2318	DinB family
S101413_RS21010	COG0778	Nitroreductase
S101413_RS21015	COG1846	Transcriptional regulator
S101413_RS21020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
S101413_RS21025	COG1846	Transcriptional regulator
S101413_RS21030	COG2153	protein acetylation
S101413_RS21040	COG0546	phosphoglycolate phosphatase activity
S101413_RS21070	COG1404	Belongs to the peptidase S8 family
S101413_RS21080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
S101413_RS21085	COG0697	spore germination
S101413_RS21120	COG1131	(ABC) transporter
S101413_RS21135	COG1331	Highly conserved protein containing a thioredoxin domain
S101413_RS21140	COG1266	CAAX protease self-immunity
S101413_RS21145	COG2814	Major facilitator Superfamily
S101413_RS21145	COG0477	Major facilitator Superfamily
S101413_RS21150	COG0346	lactoylglutathione lyase activity
S101413_RS21155	COG1609	Transcriptional regulator
S101413_RS21165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
S101413_RS21170	COG2169	Transcriptional regulator
S101413_RS21180	COG0629	single-stranded DNA binding
S101413_RS21190	COG0012	GTP binding
S101413_RS21195	COG0243	molybdopterin cofactor binding
S101413_RS21200	COG4481	Protein conserved in bacteria
S101413_RS21220	COG1475	DNA binding
S101413_RS21225	COG1192	Involved in chromosome partitioning
S101413_RS21250	COG1847	R3H domain protein
S101413_RS21255	COG0706	membrane insertase activity
S101413_RS21310	COG1863	multisubunit Na H antiporter MnhE subunit
S101413_RS21320	COG1320	monovalent cation:proton antiporter activity
S101413_RS21325	COG2050	protein possibly involved in aromatic compounds catabolism
S101413_RS21330	COG2197	response regulator
S101413_RS21365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
S101413_RS21370	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
S101413_RS21375	COG1335	isochorismatase
S101413_RS21380	COG5506	Protein of unknown function (DUF1694)
S101413_RS21405	COG1418	mRNA catabolic process