locus-tag	class	description
C7M21_RS00015	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M21_RS00020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M21_RS00025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M21_RS00030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M21_RS00035	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M21_RS00055	COG3064	Membrane
C7M21_RS00060	COG2252	PERMEase
C7M21_RS00080	COG1305	Transglutaminase-like
C7M21_RS00085	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M21_RS00090	COG0714	Associated with various cellular activities
C7M21_RS00095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M21_RS00100	COG1113	amino acid transport
C7M21_RS00105	COG2132	Multicopper oxidase
C7M21_RS00115	COG0823	Involved in the tonB-independent uptake of proteins
C7M21_RS00120	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M21_RS00125	COG1063	alcohol dehydrogenase
C7M21_RS00130	COG1595	DNA-templated transcription, initiation
C7M21_RS00140	COG2755	lipolytic protein G-D-S-L family
C7M21_RS00140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M21_RS00145	COG4260	virion core protein, lumpy skin disease virus
C7M21_RS00150	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M21_RS00155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M21_RS00160	COG1842	Phage shock protein A
C7M21_RS00170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M21_RS00175	COG2211	Major facilitator Superfamily
C7M21_RS00180	COG1063	alcohol dehydrogenase
C7M21_RS00185	COG0457	Tetratricopeptide repeat
C7M21_RS00205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M21_RS00210	COG1266	CAAX protease self-immunity
C7M21_RS00220	COG0805	protein transport
C7M21_RS00225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M21_RS00240	COG0488	(ABC) transporter
C7M21_RS00245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M21_RS00250	COG0456	acetyltransferase
C7M21_RS00255	COG1214	PFAM Peptidase M22, glycoprotease
C7M21_RS00260	COG0802	atpase or kinase
C7M21_RS00265	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M21_RS00305	COG2814	Major facilitator Superfamily
C7M21_RS00310	COG0604	alcohol dehydrogenase
C7M21_RS00315	COG3832	glyoxalase III activity
C7M21_RS00325	COG0531	amino acid
C7M21_RS00330	COG1309	transcriptional regulator
C7M21_RS00335	COG2076	Multidrug Resistance protein
C7M21_RS00340	COG2076	Multidrug Resistance protein
C7M21_RS00345	COG2807	transmembrane transport
C7M21_RS00350	COG2186	Transcriptional regulator
C7M21_RS00355	COG2188	Transcriptional regulator
C7M21_RS00360	COG2814	Major facilitator Superfamily
C7M21_RS00365	COG1388	LysM domain
C7M21_RS00370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M21_RS00385	COG1819	glycosyl
C7M21_RS00390	COG1802	Transcriptional regulator
C7M21_RS00395	COG0473	3-isopropylmalate dehydrogenase activity
C7M21_RS00400	COG2226	methyltransferase
C7M21_RS00405	COG1051	belongs to the nudix hydrolase family
C7M21_RS00410	COG0697	spore germination
C7M21_RS00415	COG4978	Transcriptional regulator
C7M21_RS00415	COG0789	Transcriptional regulator
C7M21_RS00420	COG0456	acetyltransferase
C7M21_RS00425	COG0730	response to heat
C7M21_RS00435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M21_RS00440	COG2814	Major facilitator Superfamily
C7M21_RS00450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS00455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M21_RS00465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7M21_RS00470	COG2409	Drug exporters of the RND superfamily
C7M21_RS00475	COG2197	response regulator
C7M21_RS00480	COG4585	Histidine kinase
C7M21_RS00485	COG0110	maltose O-acetyltransferase activity
C7M21_RS00495	COG0738	Major facilitator superfamily
C7M21_RS00505	COG5577	PFAM Coat F domain
C7M21_RS00510	COG1063	alcohol dehydrogenase
C7M21_RS00520	COG5577	PFAM Coat F domain
C7M21_RS00525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS00530	COG0697	spore germination
C7M21_RS00535	COG1309	transcriptional regulator
C7M21_RS00540	COG2814	Major facilitator Superfamily
C7M21_RS00575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS00585	COG0789	Transcriptional regulator
C7M21_RS00590	COG1064	alcohol dehydrogenase
C7M21_RS00615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M21_RS00620	COG2318	DinB family
C7M21_RS00625	COG0662	Cupin 2, conserved barrel domain protein
C7M21_RS00650	COG0277	FAD linked oxidase domain protein
C7M21_RS00665	COG0662	Cupin 2, conserved barrel domain protein
C7M21_RS00675	COG3621	Patatin-like phospholipase
C7M21_RS00690	COG1794	racemase activity, acting on amino acids and derivatives
C7M21_RS00695	COG1329	Transcriptional regulator
C7M21_RS00700	COG1278	Cold shock
C7M21_RS00720	COG0604	alcohol dehydrogenase
C7M21_RS00730	COG2910	NAD(P)H-binding
C7M21_RS00735	COG1959	2 iron, 2 sulfur cluster binding
C7M21_RS00750	COG2030	dehydratase
C7M21_RS00760	COG1846	Transcriptional regulator
C7M21_RS00765	COG0477	Major facilitator Superfamily
C7M21_RS00770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M21_RS00790	COG0457	Tetratricopeptide repeat
C7M21_RS00795	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M21_RS00800	COG0457	Tetratricopeptide repeat
C7M21_RS00815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M21_RS00820	COG1090	epimerase
C7M21_RS00825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M21_RS00830	COG1959	2 iron, 2 sulfur cluster binding
C7M21_RS00895	COG2183	response to ionizing radiation
C7M21_RS00900	COG2208	phosphoserine phosphatase activity
C7M21_RS00905	COG1191	sigma factor activity
C7M21_RS00915	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS00920	COG2208	phosphoserine phosphatase activity
C7M21_RS00925	COG2172	sigma factor antagonist activity
C7M21_RS00930	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS00935	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS00940	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M21_RS00945	COG0864	Transcriptional regulator
C7M21_RS00950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M21_RS00955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M21_RS00965	COG0705	Rhomboid family
C7M21_RS00970	COG3428	Bacterial PH domain
C7M21_RS00975	COG3402	PFAM membrane-flanked domain
C7M21_RS00980	COG0513	Belongs to the DEAD box helicase family
C7M21_RS00985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M21_RS00995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS01000	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M21_RS01015	COG1960	acyl-CoA dehydrogenase activity
C7M21_RS01025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M21_RS01030	COG1131	(ABC) transporter
C7M21_RS01035	COG0628	permease
C7M21_RS01040	COG1301	dicarboxylic acid transport
C7M21_RS01045	COG4565	transcriptional regulatory protein
C7M21_RS01050	COG3290	protein histidine kinase activity
C7M21_RS01055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M21_RS01060	COG3546	catalase activity
C7M21_RS01065	COG2329	Antibiotic biosynthesis monooxygenase
C7M21_RS01070	COG0662	Cupin 2, conserved barrel domain protein
C7M21_RS01075	COG3729	General stress protein
C7M21_RS01080	COG2217	Heavy metal translocating P-type atpase
C7M21_RS01085	COG2076	Multidrug Resistance protein
C7M21_RS01095	COG4876	unkown
C7M21_RS01105	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M21_RS01130	COG0028	Belongs to the TPP enzyme family
C7M21_RS01135	COG0494	nUDIX hydrolase
C7M21_RS01140	COG0531	amino acid
C7M21_RS01150	COG1215	transferase activity, transferring glycosyl groups
C7M21_RS01155	COG5298	Protein conserved in bacteria
C7M21_RS01160	COG3706	GGDEF domain
C7M21_RS01170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M21_RS01170	COG0551	DNA topoisomerase type I activity
C7M21_RS01175	COG1522	sequence-specific DNA binding
C7M21_RS01180	COG2814	Major facilitator Superfamily
C7M21_RS01190	COG3871	stress protein (general stress protein 26)
C7M21_RS01195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M21_RS01200	COG1917	Cupin 2, conserved barrel domain protein
C7M21_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS01210	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS01215	COG3711	transcriptional antiterminator
C7M21_RS01220	COG4989	oxidoreductase activity
C7M21_RS01225	COG0768	penicillin binding
C7M21_RS01230	COG2329	Antibiotic biosynthesis monooxygenase
C7M21_RS01240	COG2755	lipolytic protein G-D-S-L family
C7M21_RS01245	COG1414	Transcriptional regulator
C7M21_RS01250	COG1984	allophanate hydrolase subunit 2
C7M21_RS01255	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M21_RS01265	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M21_RS01275	COG0561	phosphatase activity
C7M21_RS01285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M21_RS01295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS01300	COG2213	PTS system mannitol-specific
C7M21_RS01310	COG1349	DNA-binding transcription factor activity
C7M21_RS01315	COG2372	response to copper ion
C7M21_RS01315	COG1276	copper resistance
C7M21_RS01320	COG4549	nuclear export factor GLE1
C7M21_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS01330	COG4975	Glucose uptake
C7M21_RS01335	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS01340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS01345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS01350	COG0640	Transcriptional regulator
C7M21_RS01355	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M21_RS01360	COG0778	Nitroreductase
C7M21_RS01365	COG1309	transcriptional regulator
C7M21_RS01370	COG2814	Major facilitator Superfamily
C7M21_RS01375	COG4607	ABC-type enterochelin transport system periplasmic component
C7M21_RS01380	COG4604	ABC transporter, ATP-binding protein
C7M21_RS01385	COG4605	iron ion homeostasis
C7M21_RS01390	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS01395	COG0527	aspartate kinase activity
C7M21_RS01410	COG0457	Tetratricopeptide repeat
C7M21_RS01415	COG3850	Histidine kinase
C7M21_RS01415	COG5002	protein histidine kinase activity
C7M21_RS01420	COG0745	RESPONSE REGULATOR receiver
C7M21_RS01425	COG0577	efflux transmembrane transporter activity
C7M21_RS01430	COG1136	(ABC) transporter
C7M21_RS01435	COG2079	MmgE PrpD family protein
C7M21_RS01445	COG1126	abc transporter atp-binding protein
C7M21_RS01450	COG0765	amino acid transport
C7M21_RS01455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS01470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M21_RS01480	COG0697	spore germination
C7M21_RS01490	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M21_RS01495	COG3104	oligopeptide transport
C7M21_RS01510	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M21_RS01515	COG0163	prenyltransferase activity
C7M21_RS01520	COG0583	DNA-binding transcription factor activity
C7M21_RS01525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS01530	COG0765	amino acid transport
C7M21_RS01535	COG1126	abc transporter atp-binding protein
C7M21_RS01540	COG2364	Membrane
C7M21_RS01550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS01555	COG0697	spore germination
C7M21_RS01570	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M21_RS01575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS01580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS01585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS01590	COG1733	regulation of RNA biosynthetic process
C7M21_RS01595	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M21_RS01600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M21_RS01605	COG3209	COG3209 Rhs family protein
C7M21_RS01615	COG2723	6-phospho-beta-galactosidase activity
C7M21_RS01625	COG1714	RDD family
C7M21_RS01630	COG1063	alcohol dehydrogenase
C7M21_RS01635	COG0523	cobalamin synthesis protein
C7M21_RS01640	COG2223	nitrite transmembrane transporter activity
C7M21_RS01645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M21_RS01650	COG0243	molybdopterin cofactor binding
C7M21_RS01655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M21_RS01660	COG2146	nitrite reductase [NAD(P)H] activity
C7M21_RS01665	COG1587	Uroporphyrinogen-III synthase
C7M21_RS01665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M21_RS01675	COG2508	Transcriptional regulator
C7M21_RS01680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M21_RS01685	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS01690	COG0506	proline dehydrogenase activity
C7M21_RS01695	COG3541	Predicted nucleotidyltransferase
C7M21_RS01700	COG3458	cephalosporin-C deacetylase activity
C7M21_RS01705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M21_RS01710	COG2271	Major facilitator Superfamily
C7M21_RS01715	COG1082	Xylose isomerase domain protein TIM barrel
C7M21_RS01720	COG1660	Displays ATPase and GTPase activities
C7M21_RS01735	COG3665	Urea carboxylase-associated protein
C7M21_RS01740	COG1113	amino acid transport
C7M21_RS01745	COG3403	YqcI/YcgG family
C7M21_RS01750	COG1280	lysine exporter protein (LysE YggA)
C7M21_RS01755	COG1846	Transcriptional regulator
C7M21_RS01760	COG2814	Major facilitator Superfamily
C7M21_RS01770	COG0366	Alpha amylase catalytic
C7M21_RS01780	COG1288	antiporter activity
C7M21_RS01785	COG1473	amidohydrolase
C7M21_RS01790	COG2113	Glycine betaine
C7M21_RS01795	COG4176	ABC-type proline glycine betaine transport system permease component
C7M21_RS01800	COG4175	Glycine betaine
C7M21_RS01800	COG0517	IMP dehydrogenase activity
C7M21_RS01805	COG0477	Major facilitator Superfamily
C7M21_RS01810	COG3853	Toxic anion resistance protein (TelA)
C7M21_RS01820	COG0861	Integral membrane protein TerC family
C7M21_RS01825	COG2310	stress, protein
C7M21_RS01830	COG2310	stress, protein
C7M21_RS01835	COG2310	stress, protein
C7M21_RS01840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M21_RS01845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M21_RS01850	COG1121	(ABC) transporter
C7M21_RS01855	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M21_RS01860	COG0366	Alpha amylase catalytic
C7M21_RS01865	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS01870	COG0457	Tetratricopeptide repeat
C7M21_RS01875	COG1876	peptidase activity
C7M21_RS01880	COG1595	DNA-templated transcription, initiation
C7M21_RS01885	COG1595	DNA-templated transcription, initiation
C7M21_RS01895	COG0667	Aldo Keto reductase
C7M21_RS01900	COG1405	negative regulation of cell septum assembly
C7M21_RS01900	COG3012	SEC-C Motif Domain Protein
C7M21_RS01905	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M21_RS01910	COG0252	asparaginase activity
C7M21_RS01915	COG1309	transcriptional regulator
C7M21_RS01920	COG0477	Major facilitator Superfamily
C7M21_RS01925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M21_RS01935	COG0805	protein transport
C7M21_RS01940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M21_RS01945	COG3540	Alkaline phosphatase
C7M21_RS01950	COG3773	Cell wall hydrolase
C7M21_RS01960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS01965	COG2259	Doxx family
C7M21_RS01970	COG0346	lactoylglutathione lyase activity
C7M21_RS01975	COG0778	Nitroreductase
C7M21_RS01980	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M21_RS01995	COG0784	Response regulator, receiver
C7M21_RS02000	COG4191	Histidine kinase
C7M21_RS02005	COG2066	Belongs to the glutaminase family
C7M21_RS02010	COG1115	amino acid carrier protein
C7M21_RS02015	COG2040	homocysteine
C7M21_RS02020	COG0833	amino acid
C7M21_RS02025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS02030	COG1301	dicarboxylic acid transport
C7M21_RS02045	COG0688	phosphatidylethanolamine metabolic process
C7M21_RS02050	COG0586	Pfam SNARE associated Golgi protein
C7M21_RS02055	COG1183	phosphatidylcholine synthase activity
C7M21_RS02065	COG0371	Dehydrogenase
C7M21_RS02080	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS02090	COG2368	4-hydroxyphenylacetate
C7M21_RS02100	COG2271	Major facilitator Superfamily
C7M21_RS02105	COG0584	glycerophosphoryl diester phosphodiesterase
C7M21_RS02120	COG0531	amino acid
C7M21_RS02150	COG1011	Hydrolase
C7M21_RS02155	COG1113	amino acid transport
C7M21_RS02160	COG1846	Transcriptional regulator
C7M21_RS02165	COG1380	Effector of murein hydrolase LrgA
C7M21_RS02170	COG1346	cytolysis
C7M21_RS02220	COG4856	YbbR-like protein
C7M21_RS02225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M21_RS02230	COG5662	AntiSigma factor
C7M21_RS02235	COG1595	DNA-templated transcription, initiation
C7M21_RS02265	COG1683	Conserved Protein
C7M21_RS02270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M21_RS02280	COG1263	PTS System
C7M21_RS02280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS02285	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M21_RS02290	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M21_RS02295	COG3876	Protein conserved in bacteria
C7M21_RS02300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M21_RS02300	COG2207	Transcriptional regulator
C7M21_RS02305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M21_RS02310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS02315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS02320	COG2819	hydrolase of the alpha beta superfamily
C7M21_RS02325	COG0385	Bile acid
C7M21_RS02330	COG0659	secondary active sulfate transmembrane transporter activity
C7M21_RS02345	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS02350	COG0738	Major facilitator superfamily
C7M21_RS02410	COG0726	polysaccharide deacetylase
C7M21_RS02415	COG2194	sulfuric ester hydrolase activity
C7M21_RS02425	COG0489	protein tyrosine kinase activity
C7M21_RS02430	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS02440	COG2318	DinB family
C7M21_RS02445	COG2226	methyltransferase
C7M21_RS02465	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M21_RS02470	COG1122	ATPase activity
C7M21_RS02475	COG1122	ATPase activity
C7M21_RS02500	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M21_RS02505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M21_RS02515	COG0024	Methionine aminopeptidase
C7M21_RS02525	COG0201	protein transport
C7M21_RS02535	COG1841	ribosomal large subunit assembly
C7M21_RS02585	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M21_RS02590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M21_RS02600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M21_RS02605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M21_RS02615	COG0089	rRNA binding
C7M21_RS02630	COG0051	transcription antitermination factor activity, RNA binding
C7M21_RS02635	COG0596	Alpha beta hydrolase
C7M21_RS02660	COG1358	cellular component organization or biogenesis
C7M21_RS02675	COG2813	Specifically methylates the guanine in position
C7M21_RS02680	COG0222	ribosome binding
C7M21_RS02695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M21_RS02700	COG0250	Participates in transcription elongation, termination and antitermination
C7M21_RS02705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M21_RS02710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M21_RS02715	COG1595	DNA-templated transcription, initiation
C7M21_RS02720	COG3688	RNA-binding protein containing a PIN domain
C7M21_RS02725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M21_RS02730	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M21_RS02740	COG1045	serine acetyltransferase
C7M21_RS02760	COG4956	integral membrane protein (PIN domain superfamily)
C7M21_RS02765	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M21_RS02770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M21_RS02775	COG0542	response to heat
C7M21_RS02785	COG3880	PFAM UvrB UvrC protein
C7M21_RS02790	COG4463	regulation of RNA biosynthetic process
C7M21_RS02870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M21_RS02875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M21_RS02880	COG1396	sequence-specific DNA binding
C7M21_RS02885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M21_RS02890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M21_RS02895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M21_RS02900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS02905	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M21_RS02910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M21_RS02915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M21_RS02920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M21_RS02935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M21_RS02945	COG0037	tRNA processing
C7M21_RS02950	COG0515	serine threonine protein kinase
C7M21_RS02955	COG2304	oxidoreductase activity
C7M21_RS02960	COG2208	phosphoserine phosphatase activity
C7M21_RS02975	COG1098	S1 RNA binding domain
C7M21_RS02980	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M21_RS02995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M21_RS03000	COG3956	TIGRFAM MazG family protein
C7M21_RS03005	COG2244	polysaccharide biosynthetic process
C7M21_RS03010	COG2002	toxin-antitoxin pair type II binding
C7M21_RS03015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M21_RS03035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M21_RS03050	COG0251	oxidation-reduction process
C7M21_RS03055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M21_RS03070	COG4466	Protein conserved in bacteria
C7M21_RS03080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M21_RS03085	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M21_RS03090	COG3583	domain protein
C7M21_RS03090	COG3584	3D domain protein
C7M21_RS03095	COG0084	hydrolase, TatD family'
C7M21_RS03100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M21_RS03100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M21_RS03105	COG2002	toxin-antitoxin pair type II binding
C7M21_RS03110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M21_RS03120	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M21_RS03130	COG1774	PSP1 C-terminal conserved region
C7M21_RS03135	COG0470	DNA polymerase III
C7M21_RS03140	COG1728	Protein conserved in bacteria
C7M21_RS03145	COG3870	Protein conserved in bacteria
C7M21_RS03155	COG1982	Orn Lys Arg decarboxylase major
C7M21_RS03160	COG3853	Toxic anion resistance protein (TelA)
C7M21_RS03165	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M21_RS03215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M21_RS03220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M21_RS03230	COG0590	tRNA wobble adenosine to inosine editing
C7M21_RS03235	COG1335	isochorismatase
C7M21_RS03240	COG3858	chitin binding
C7M21_RS03240	COG1388	LysM domain
C7M21_RS03245	COG1428	Deoxynucleoside kinase
C7M21_RS03250	COG1428	Deoxynucleoside kinase
C7M21_RS03260	COG1929	Belongs to the glycerate kinase type-1 family
C7M21_RS03280	COG1686	Belongs to the peptidase S11 family
C7M21_RS03285	COG0517	IMP dehydrogenase activity
C7M21_RS03285	COG0516	GMP reductase activity
C7M21_RS03320	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M21_RS03325	COG0187	DNA topoisomerase II activity
C7M21_RS03340	COG2501	S4 domain
C7M21_RS03345	COG0592	DNA-directed DNA polymerase activity
C7M21_RS03355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M21_RS03365	COG0706	membrane insertase activity
C7M21_RS03370	COG1847	R3H domain protein
C7M21_RS03395	COG1192	Involved in chromosome partitioning
C7M21_RS03400	COG1475	DNA binding
C7M21_RS03415	COG3949	Membrane
C7M21_RS03420	COG4481	Protein conserved in bacteria
C7M21_RS03425	COG0243	molybdopterin cofactor binding
C7M21_RS03430	COG0012	GTP binding
C7M21_RS03440	COG0629	single-stranded DNA binding
C7M21_RS03450	COG2169	Transcriptional regulator
C7M21_RS03455	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M21_RS03460	COG0708	Exodeoxyribonuclease III
C7M21_RS03465	COG1609	Transcriptional regulator
C7M21_RS03470	COG0346	lactoylglutathione lyase activity
C7M21_RS03475	COG0477	Major facilitator Superfamily
C7M21_RS03475	COG2814	Major facilitator Superfamily
C7M21_RS03480	COG1266	CAAX protease self-immunity
C7M21_RS03485	COG1331	Highly conserved protein containing a thioredoxin domain
C7M21_RS03490	COG0697	spore germination
C7M21_RS03495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS03515	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS03520	COG0583	DNA-binding transcription factor activity
C7M21_RS03525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M21_RS03535	COG2153	protein acetylation
C7M21_RS03540	COG1846	Transcriptional regulator
C7M21_RS03545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS03550	COG1846	Transcriptional regulator
C7M21_RS03555	COG0778	Nitroreductase
C7M21_RS03565	COG0583	DNA-binding transcription factor activity
C7M21_RS03570	COG2814	Major facilitator Superfamily
C7M21_RS03580	COG0583	DNA-binding transcription factor activity
C7M21_RS03585	COG2211	Major facilitator Superfamily
C7M21_RS03590	COG2318	DinB family
C7M21_RS03595	COG1802	Transcriptional regulator
C7M21_RS03600	COG1621	beta-fructofuranosidase activity
C7M21_RS03605	COG1621	beta-fructofuranosidase activity
C7M21_RS03610	COG0697	spore germination
C7M21_RS03620	COG1733	regulation of RNA biosynthetic process
C7M21_RS03625	COG5577	PFAM Coat F domain
C7M21_RS03635	COG4241	membrane
C7M21_RS03640	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M21_RS03660	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS03665	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M21_RS03680	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M21_RS03685	COG3093	addiction module antidote protein HigA
C7M21_RS03705	COG0305	Participates in initiation and elongation during chromosome replication
C7M21_RS03710	COG0346	lactoylglutathione lyase activity
C7M21_RS03740	COG0745	RESPONSE REGULATOR receiver
C7M21_RS03745	COG5002	protein histidine kinase activity
C7M21_RS03750	COG4863	YycH protein
C7M21_RS03755	COG4853	Protein conserved in bacteria
C7M21_RS03760	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M21_RS03765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M21_RS03770	COG0745	RESPONSE REGULATOR receiver
C7M21_RS03775	COG3850	Histidine kinase
C7M21_RS03775	COG5002	protein histidine kinase activity
C7M21_RS03780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M21_RS03795	COG0488	(ABC) transporter
C7M21_RS03805	COG3829	transcription factor binding
C7M21_RS03810	COG0640	Transcriptional regulator
C7M21_RS03815	COG5658	integral membrane protein
C7M21_RS03820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M21_RS03825	COG0833	amino acid
C7M21_RS03830	COG0010	Belongs to the arginase family
C7M21_RS03835	COG0457	Tetratricopeptide repeat
C7M21_RS03840	COG0456	acetyltransferase
C7M21_RS03845	COG0667	Aldo Keto reductase
C7M21_RS03850	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M21_RS03890	COG0210	DNA helicase
C7M21_RS03920	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M21_RS03925	COG2068	MobA-Related Protein
C7M21_RS03940	COG2080	2 iron, 2 sulfur cluster binding
C7M21_RS03950	COG1113	amino acid transport
C7M21_RS03955	COG3177	Filamentation induced by cAMP protein fic
C7M21_RS03960	COG3634	alkyl hydroperoxide reductase activity
C7M21_RS03965	COG0450	alkyl hydroperoxide reductase
C7M21_RS03975	COG1714	RDD family
C7M21_RS03980	COG2814	Major facilitator Superfamily
C7M21_RS03985	COG0640	Transcriptional regulator
C7M21_RS03995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M21_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS04005	COG1309	transcriptional regulator
C7M21_RS04010	COG3239	Fatty acid desaturase
C7M21_RS04015	COG4585	Histidine kinase
C7M21_RS04020	COG2197	response regulator
C7M21_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS04040	COG2814	Major facilitator Superfamily
C7M21_RS04045	COG0667	Aldo Keto reductase
C7M21_RS04050	COG1349	DNA-binding transcription factor activity
C7M21_RS04080	COG2814	Major facilitator Superfamily
C7M21_RS04090	COG1082	Xylose isomerase domain protein TIM barrel
C7M21_RS04105	COG0745	RESPONSE REGULATOR receiver
C7M21_RS04110	COG2205	protein histidine kinase activity
C7M21_RS04115	COG1136	(ABC) transporter
C7M21_RS04120	COG0577	efflux transmembrane transporter activity
C7M21_RS04125	COG5294	Protein conserved in bacteria
C7M21_RS04130	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M21_RS04160	COG0561	phosphatase activity
C7M21_RS04165	COG2390	Transcriptional regulator
C7M21_RS04175	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M21_RS04180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M21_RS04185	COG0833	amino acid
C7M21_RS04190	COG0010	Belongs to the arginase family
C7M21_RS04215	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M21_RS04220	COG0494	nUDIX hydrolase
C7M21_RS04230	COG2190	(PTS) system
C7M21_RS04230	COG1263	PTS System
C7M21_RS04230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS04235	COG2723	6-phospho-beta-galactosidase activity
C7M21_RS04240	COG0589	response to stress
C7M21_RS04245	COG0697	spore germination
C7M21_RS04255	COG3209	COG3209 Rhs family protein
C7M21_RS04310	COG0513	Belongs to the DEAD box helicase family
C7M21_RS04315	COG2270	Major facilitator Superfamily
C7M21_RS04320	COG3711	transcriptional antiterminator
C7M21_RS04325	COG2273	Hydrolase Family 16
C7M21_RS04330	COG2851	Citrate transporter
C7M21_RS04335	COG0753	catalase activity
C7M21_RS04335	COG0693	protein deglycase activity
C7M21_RS04350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M21_RS04355	COG0500	methyltransferase
C7M21_RS04360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M21_RS04365	COG4894	glucomannan catabolic process
C7M21_RS04375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M21_RS04385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS04390	COG2508	Transcriptional regulator
C7M21_RS04395	COG3842	ATPase activity
C7M21_RS04400	COG0726	polysaccharide deacetylase
C7M21_RS04405	COG3493	citrate carrier protein
C7M21_RS04410	COG1271	oxidase subunit
C7M21_RS04415	COG1294	oxidase, subunit
C7M21_RS04420	COG4988	ABC transporter
C7M21_RS04425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M21_RS04430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M21_RS04435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M21_RS04440	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M21_RS04445	COG0753	catalase activity
C7M21_RS04455	COG1482	cell wall glycoprotein biosynthetic process
C7M21_RS04460	COG1940	carbohydrate kinase activity
C7M21_RS04465	COG2723	6-phospho-beta-galactosidase activity
C7M21_RS04470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS04475	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M21_RS04480	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS04485	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M21_RS04490	COG0640	Transcriptional regulator
C7M21_RS04500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS04505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS04515	COG3711	transcriptional antiterminator
C7M21_RS04515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS04520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS04525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS04530	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M21_RS04535	COG1486	melibiose metabolic process
C7M21_RS04540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS04545	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M21_RS04555	COG1696	Membrane protein involved in D-alanine export
C7M21_RS04570	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M21_RS04575	COG2357	RelA SpoT domain protein
C7M21_RS04580	COG1442	glycosyl transferase family 8
C7M21_RS04585	COG1404	Belongs to the peptidase S8 family
C7M21_RS04590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS04595	COG0346	lactoylglutathione lyase activity
C7M21_RS04600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M21_RS04605	COG5504	Zn-dependent protease
C7M21_RS04610	COG0789	Transcriptional regulator
C7M21_RS04615	COG4895	conserved protein (DUF2196)
C7M21_RS04620	COG1346	cytolysis
C7M21_RS04630	COG0583	DNA-binding transcription factor activity
C7M21_RS04645	COG2822	iron ion transport
C7M21_RS04650	COG2837	iron assimilation
C7M21_RS04655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M21_RS04675	COG1309	transcriptional regulator
C7M21_RS04680	COG2246	polysaccharide biosynthetic process
C7M21_RS04685	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M21_RS04690	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M21_RS04700	COG2261	transglycosylase associated protein
C7M21_RS04705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M21_RS04710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M21_RS04730	COG0454	-acetyltransferase
C7M21_RS04735	COG0772	Belongs to the SEDS family
C7M21_RS04740	COG0778	Nitroreductase
C7M21_RS04745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M21_RS04750	COG1404	Belongs to the peptidase S8 family
C7M21_RS04760	COG3711	transcriptional antiterminator
C7M21_RS04765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS04765	COG1263	PTS System
C7M21_RS04770	COG1621	beta-fructofuranosidase activity
C7M21_RS04780	COG0351	phosphomethylpyrimidine kinase
C7M21_RS04785	COG1695	Transcriptional regulator
C7M21_RS04800	COG1216	Glycosyl transferase, family 2
C7M21_RS04815	COG2233	PERMEase
C7M21_RS04820	COG2363	Small membrane protein
C7M21_RS04830	COG0463	Glycosyl transferase, family 2
C7M21_RS04835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M21_RS04840	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M21_RS04845	COG0456	acetyltransferase
C7M21_RS04850	COG2089	acid synthase
C7M21_RS04855	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M21_RS04860	COG3980	spore coat polysaccharide biosynthesis protein
C7M21_RS04865	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M21_RS04870	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M21_RS04875	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M21_RS04880	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M21_RS04890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M21_RS04895	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS04900	COG4187	Peptidase family M20/M25/M40
C7M21_RS04905	COG0833	amino acid
C7M21_RS04910	COG2814	Major facilitator Superfamily
C7M21_RS04915	COG2814	Major facilitator Superfamily
C7M21_RS04945	COG0436	Aminotransferase
C7M21_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS04960	COG0280	phosphate acetyltransferase
C7M21_RS04965	COG2855	membrane
C7M21_RS04970	COG0583	DNA-binding transcription factor activity
C7M21_RS05000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M21_RS05005	COG1131	(ABC) transporter
C7M21_RS05015	COG1695	Transcriptional regulator
C7M21_RS05030	COG1078	dGTPase activity
C7M21_RS05035	COG3465	dGTPase activity
C7M21_RS05040	COG0531	amino acid
C7M21_RS05045	COG1846	Transcriptional regulator
C7M21_RS05050	COG1942	4-Oxalocrotonate Tautomerase
C7M21_RS05055	COG1994	Peptidase M50
C7M21_RS05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M21_RS05075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M21_RS05080	COG0010	Belongs to the arginase family
C7M21_RS05125	COG0457	Tetratricopeptide repeat
C7M21_RS05130	COG3391	amine dehydrogenase activity
C7M21_RS05135	COG3391	amine dehydrogenase activity
C7M21_RS05145	COG4506	Protein conserved in bacteria
C7M21_RS05155	COG2223	nitrite transmembrane transporter activity
C7M21_RS05160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M21_RS05170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M21_RS05175	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M21_RS05180	COG1140	nitrate reductase beta subunit
C7M21_RS05185	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M21_RS05190	COG2181	nitrate reductase activity
C7M21_RS05200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M21_RS05205	COG1132	(ABC) transporter
C7M21_RS05220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M21_RS05225	COG2181	nitrate reductase activity
C7M21_RS05225	COG0247	lactate metabolic process
C7M21_RS05240	COG4821	SIS domain
C7M21_RS05245	COG2204	response regulator
C7M21_RS05250	COG0191	fructose-bisphosphate aldolase activity
C7M21_RS05260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M21_RS05265	COG1494	fructose-1,6-bisphosphatase
C7M21_RS05270	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M21_RS05275	COG0254	rRNA binding
C7M21_RS05285	COG0281	malic enzyme
C7M21_RS05290	COG0679	Auxin Efflux Carrier
C7M21_RS05295	COG0789	Transcriptional regulator
C7M21_RS05300	COG0346	lactoylglutathione lyase activity
C7M21_RS05305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M21_RS05310	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M21_RS05330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M21_RS05335	COG0009	L-threonylcarbamoyladenylate synthase
C7M21_RS05345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M21_RS05350	COG0698	ribose 5-phosphate isomerase
C7M21_RS05380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M21_RS05420	COG4836	Membrane
C7M21_RS05430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M21_RS05435	COG2385	sporulation resulting in formation of a cellular spore
C7M21_RS05440	COG2304	oxidoreductase activity
C7M21_RS05445	COG2304	oxidoreductase activity
C7M21_RS05450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M21_RS05460	COG0457	Tetratricopeptide repeat
C7M21_RS05465	COG1994	Peptidase M50
C7M21_RS05470	COG3237	CsbD-like
C7M21_RS05475	COG0831	urea catabolic process
C7M21_RS05490	COG1959	2 iron, 2 sulfur cluster binding
C7M21_RS05495	COG0726	polysaccharide deacetylase
C7M21_RS05505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M21_RS05520	COG1247	-acetyltransferase
C7M21_RS05525	COG0739	heme binding
C7M21_RS05535	COG0671	phosphoesterase, PA-phosphatase related
C7M21_RS05540	COG0772	Belongs to the SEDS family
C7M21_RS05545	COG0347	Belongs to the P(II) protein family
C7M21_RS05550	COG0004	ammonium transporteR
C7M21_RS05555	COG1335	isochorismatase
C7M21_RS05560	COG0477	Major facilitator Superfamily
C7M21_RS05565	COG1953	Uracil, thiamine, allantoin
C7M21_RS05570	COG2814	Major facilitator Superfamily
C7M21_RS05575	COG1846	Transcriptional regulator
C7M21_RS05580	COG1609	Transcriptional regulator
C7M21_RS05585	COG1077	Cell shape determining protein MreB Mrl
C7M21_RS05590	COG4786	Flagellar basal body rod
C7M21_RS05595	COG4786	Flagellar basal body rod
C7M21_RS05600	COG0457	Tetratricopeptide repeat
C7M21_RS05625	COG0629	single-stranded DNA binding
C7M21_RS05630	COG1349	DNA-binding transcription factor activity
C7M21_RS05635	COG0561	phosphatase activity
C7M21_RS05640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M21_RS05645	COG4715	Zinc finger, swim domain protein
C7M21_RS05655	COG3944	biosynthesis protein
C7M21_RS05660	COG0489	protein tyrosine kinase activity
C7M21_RS05665	COG4464	protein tyrosine phosphatase activity
C7M21_RS05670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M21_RS05675	COG3878	Protein conserved in bacteria
C7M21_RS05690	COG5444	nuclease activity
C7M21_RS05710	COG2059	Chromate
C7M21_RS05715	COG2059	Chromate
C7M21_RS05720	COG1522	sequence-specific DNA binding
C7M21_RS05725	COG0405	Gamma-glutamyltransferase
C7M21_RS05735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M21_RS05745	COG5337	Spore coat protein CotH
C7M21_RS05760	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M21_RS05765	COG0583	DNA-binding transcription factor activity
C7M21_RS05770	COG0028	Belongs to the TPP enzyme family
C7M21_RS05775	COG3527	Alpha-acetolactate decarboxylase
C7M21_RS05780	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M21_RS05785	COG3103	Sh3 type 3 domain protein
C7M21_RS05790	COG1879	ABC-type sugar transport system periplasmic component
C7M21_RS05795	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M21_RS05800	COG1129	ABC transporter
C7M21_RS05810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M21_RS05815	COG1609	Transcriptional regulator
C7M21_RS05825	COG0814	amino acid
C7M21_RS05830	COG0697	spore germination
C7M21_RS05835	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M21_RS05845	COG2843	Capsule synthesis protein
C7M21_RS05855	COG0791	NLP P60 protein
C7M21_RS05860	COG2433	Pfam Transposase IS66
C7M21_RS05865	COG0561	phosphatase activity
C7M21_RS05870	COG1316	TRANSCRIPTIONal
C7M21_RS05875	COG2814	Major facilitator Superfamily
C7M21_RS05880	COG1215	transferase activity, transferring glycosyl groups
C7M21_RS05890	COG0814	amino acid
C7M21_RS05895	COG0697	spore germination
C7M21_RS05900	COG1482	cell wall glycoprotein biosynthetic process
C7M21_RS05905	COG4193	domain, Protein
C7M21_RS05910	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M21_RS05915	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M21_RS05920	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M21_RS05930	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M21_RS05935	COG1682	transport, permease protein
C7M21_RS05940	COG1134	teichoic acid transport
C7M21_RS05945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M21_RS05950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M21_RS05955	COG1316	TRANSCRIPTIONal
C7M21_RS05965	COG2385	sporulation resulting in formation of a cellular spore
C7M21_RS05965	COG2247	cell wall binding repeat
C7M21_RS05970	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS05970	COG2247	cell wall binding repeat
C7M21_RS05980	COG2244	polysaccharide biosynthetic process
C7M21_RS05985	COG0297	glycogen (starch) synthase activity
C7M21_RS05985	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS05990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M21_RS05995	COG3307	-O-antigen
C7M21_RS06000	COG3206	protein involved in exopolysaccharide biosynthesis
C7M21_RS06005	COG1215	transferase activity, transferring glycosyl groups
C7M21_RS06010	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS06015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M21_RS06020	COG1316	TRANSCRIPTIONal
C7M21_RS06025	COG1739	Uncharacterized protein family UPF0029
C7M21_RS06030	COG4585	Histidine kinase
C7M21_RS06035	COG2197	response regulator
C7M21_RS06040	COG1307	EDD domain protein, DegV family
C7M21_RS06045	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M21_RS06055	COG1040	competence protein
C7M21_RS06065	COG2747	anti-sigma28 factor FlgM
C7M21_RS06070	COG3418	PFAM FlgN family protein
C7M21_RS06075	COG1256	bacterial-type flagellum assembly
C7M21_RS06075	COG4786	Flagellar basal body rod
C7M21_RS06080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M21_RS06100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M21_RS06105	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M21_RS06110	COG1516	flagellar protein fliS
C7M21_RS06125	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M21_RS06140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS06145	COG2010	Cytochrome c
C7M21_RS06150	COG2884	Cell division ATP-binding protein ftsE
C7M21_RS06155	COG2177	Part of the ABC transporter FtsEX involved in
C7M21_RS06160	COG3420	alginic acid biosynthetic process
C7M21_RS06165	COG0793	Belongs to the peptidase S41A family
C7M21_RS06165	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS06175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M21_RS06180	COG2814	Major facilitator Superfamily
C7M21_RS06185	COG1309	transcriptional regulator
C7M21_RS06190	COG3848	Pyruvate phosphate dikinase
C7M21_RS06190	COG0574	Belongs to the PEP-utilizing enzyme family
C7M21_RS06195	COG4897	Protein conserved in bacteria
C7M21_RS06205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M21_RS06220	COG3595	metallopeptidase activity
C7M21_RS06225	COG1983	PspC domain protein
C7M21_RS06230	COG1950	PFAM Membrane protein of
C7M21_RS06235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M21_RS06240	COG1309	transcriptional regulator
C7M21_RS06255	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M21_RS06275	COG0110	maltose O-acetyltransferase activity
C7M21_RS06280	COG4990	cell redox homeostasis
C7M21_RS06295	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M21_RS06320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M21_RS06320	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M21_RS06325	COG1132	(ABC) transporter
C7M21_RS06330	COG0745	RESPONSE REGULATOR receiver
C7M21_RS06335	COG5002	protein histidine kinase activity
C7M21_RS06340	COG0457	Tetratricopeptide repeat
C7M21_RS06345	COG0791	NLP P60 protein
C7M21_RS06345	COG3883	PFAM NLP P60 protein
C7M21_RS06350	COG0492	ferredoxin-NADP+ reductase activity
C7M21_RS06355	COG1051	belongs to the nudix hydrolase family
C7M21_RS06365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M21_RS06375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS06380	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M21_RS06395	COG4290	ribonuclease
C7M21_RS06400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M21_RS06405	COG0288	reversible hydration of carbon dioxide
C7M21_RS06410	COG0659	secondary active sulfate transmembrane transporter activity
C7M21_RS06415	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M21_RS06420	COG1611	Belongs to the LOG family
C7M21_RS06425	COG2814	Major facilitator Superfamily
C7M21_RS06425	COG0477	Major facilitator Superfamily
C7M21_RS06430	COG2828	Protein conserved in bacteria
C7M21_RS06435	COG0583	DNA-binding transcription factor activity
C7M21_RS06445	COG1609	Transcriptional regulator
C7M21_RS06450	COG2223	nitrite transmembrane transporter activity
C7M21_RS06500	COG3479	Phenolic acid decarboxylase
C7M21_RS06505	COG0456	acetyltransferase
C7M21_RS06510	COG2364	Membrane
C7M21_RS06515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M21_RS06525	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M21_RS06530	COG1396	sequence-specific DNA binding
C7M21_RS06535	COG3944	biosynthesis protein
C7M21_RS06540	COG0489	protein tyrosine kinase activity
C7M21_RS06545	COG1086	Polysaccharide biosynthesis protein
C7M21_RS06550	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS06555	COG1215	transferase activity, transferring glycosyl groups
C7M21_RS06560	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS06570	COG1216	Glycosyl transferase, family 2
C7M21_RS06575	COG5039	Polysaccharide pyruvyl transferase
C7M21_RS06580	COG1216	Glycosyl transferase, family 2
C7M21_RS06585	COG2244	polysaccharide biosynthetic process
C7M21_RS06590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M21_RS06595	COG0110	maltose O-acetyltransferase activity
C7M21_RS06600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M21_RS06605	COG5039	Polysaccharide pyruvyl transferase
C7M21_RS06615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M21_RS06620	COG1620	l-lactate permease
C7M21_RS06625	COG2186	Transcriptional regulator
C7M21_RS06630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS06655	COG1070	Carbohydrate kinase
C7M21_RS06660	COG1737	Transcriptional regulator
C7M21_RS06670	COG0561	phosphatase activity
C7M21_RS06680	COG1609	Transcriptional regulator
C7M21_RS06690	COG1113	amino acid transport
C7M21_RS06695	COG0697	spore germination
C7M21_RS06700	COG0583	DNA-binding transcription factor activity
C7M21_RS06710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M21_RS06715	COG1609	Transcriptional regulator
C7M21_RS06720	COG2814	Major facilitator Superfamily
C7M21_RS06725	COG2390	Transcriptional regulator
C7M21_RS06730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M21_RS06735	COG0126	phosphoglycerate kinase activity
C7M21_RS06755	COG2234	aminopeptidase activity
C7M21_RS06765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M21_RS06770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS06775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M21_RS06790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M21_RS06805	COG0456	acetyltransferase
C7M21_RS06810	COG4640	response to antibiotic
C7M21_RS06815	COG3064	Membrane
C7M21_RS06820	COG2095	MarC family integral membrane protein
C7M21_RS06825	COG1510	regulation of RNA biosynthetic process
C7M21_RS06830	COG0517	IMP dehydrogenase activity
C7M21_RS06830	COG1125	glycine betaine transport
C7M21_RS06835	COG1174	glycine betaine transport
C7M21_RS06840	COG1732	Glycine betaine
C7M21_RS06845	COG1174	glycine betaine transport
C7M21_RS06850	COG1510	regulation of RNA biosynthetic process
C7M21_RS06855	COG1125	glycine betaine transport
C7M21_RS06855	COG0517	IMP dehydrogenase activity
C7M21_RS06860	COG1174	glycine betaine transport
C7M21_RS06865	COG1732	Glycine betaine
C7M21_RS06870	COG1174	glycine betaine transport
C7M21_RS06900	COG1733	regulation of RNA biosynthetic process
C7M21_RS06905	COG1396	sequence-specific DNA binding
C7M21_RS06910	COG1396	sequence-specific DNA binding
C7M21_RS06915	COG1476	TRANSCRIPTIONal
C7M21_RS06920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M21_RS06925	COG1647	Serine aminopeptidase, S33
C7M21_RS06930	COG0557	exoribonuclease II activity
C7M21_RS06945	COG2732	(Barnase) inhibitor
C7M21_RS06950	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS06955	COG0583	DNA-binding transcription factor activity
C7M21_RS06960	COG0454	-acetyltransferase
C7M21_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS06970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS06975	COG0765	amino acid transport
C7M21_RS06980	COG0765	amino acid transport
C7M21_RS06985	COG1126	abc transporter atp-binding protein
C7M21_RS06990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M21_RS06995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M21_RS07000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M21_RS07015	COG2814	Major facilitator Superfamily
C7M21_RS07030	COG0673	inositol 2-dehydrogenase activity
C7M21_RS07035	COG1937	Protein conserved in bacteria
C7M21_RS07040	COG2608	mercury ion transmembrane transporter activity
C7M21_RS07045	COG2217	Heavy metal translocating P-type atpase
C7M21_RS07050	COG2217	Heavy metal translocating P-type atpase
C7M21_RS07055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M21_RS07060	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M21_RS07070	COG2860	membrane
C7M21_RS07075	COG3973	AAA domain
C7M21_RS07080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M21_RS07100	COG0656	L-ascorbic acid biosynthetic process
C7M21_RS07105	COG0842	Transport permease protein
C7M21_RS07115	COG1131	(ABC) transporter
C7M21_RS07120	COG3850	Histidine kinase
C7M21_RS07125	COG2197	response regulator
C7M21_RS07130	COG4149	molybdate abc transporter
C7M21_RS07135	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M21_RS07140	COG1910	domain protein
C7M21_RS07145	COG1368	sulfuric ester hydrolase activity
C7M21_RS07150	COG1988	membrane-bound metal-dependent
C7M21_RS07160	COG0531	amino acid
C7M21_RS07165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M21_RS07170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS07175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS07180	COG1120	ATPase activity
C7M21_RS07190	COG2140	Oxalate decarboxylase
C7M21_RS07200	COG1191	sigma factor activity
C7M21_RS07210	COG0745	RESPONSE REGULATOR receiver
C7M21_RS07215	COG2205	protein histidine kinase activity
C7M21_RS07220	COG3386	PFAM SMP-30 Gluconolaconase
C7M21_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS07230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M21_RS07235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M21_RS07240	COG1120	ATPase activity
C7M21_RS07245	COG2096	Adenosyltransferase
C7M21_RS07250	COG2814	Major facilitator Superfamily
C7M21_RS07255	COG4758	membrane
C7M21_RS07260	COG1842	Phage shock protein A
C7M21_RS07265	COG3595	metallopeptidase activity
C7M21_RS07270	COG4758	membrane
C7M21_RS07275	COG4585	Histidine kinase
C7M21_RS07280	COG2197	response regulator
C7M21_RS07290	COG0814	amino acid
C7M21_RS07295	COG0697	spore germination
C7M21_RS07305	COG0114	fumarate hydratase activity
C7M21_RS07310	COG1309	transcriptional regulator
C7M21_RS07320	COG2770	Histidine kinase
C7M21_RS07320	COG2205	protein histidine kinase activity
C7M21_RS07325	COG0745	RESPONSE REGULATOR receiver
C7M21_RS07330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M21_RS07335	COG0783	Belongs to the Dps family
C7M21_RS07340	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS07355	COG1120	ATPase activity
C7M21_RS07375	COG0583	DNA-binding transcription factor activity
C7M21_RS07380	COG0477	Major facilitator Superfamily
C7M21_RS07385	COG1846	Transcriptional regulator
C7M21_RS07390	COG5577	PFAM Coat F domain
C7M21_RS07410	COG1024	Enoyl-CoA hydratase
C7M21_RS07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M21_RS07415	COG0183	Belongs to the thiolase family
C7M21_RS07420	COG1960	acyl-CoA dehydrogenase activity
C7M21_RS07425	COG1393	Belongs to the ArsC family
C7M21_RS07440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M21_RS07445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS07455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M21_RS07460	COG2011	ABC-type metal ion transport system permease component
C7M21_RS07465	COG1464	Belongs to the NlpA lipoprotein family
C7M21_RS07470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M21_RS07480	COG0396	ATPase activity
C7M21_RS07485	COG0719	Fe-S assembly protein
C7M21_RS07490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M21_RS07495	COG0822	iron-sulfur transferase activity
C7M21_RS07500	COG0719	Fe-S assembly protein
C7M21_RS07505	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS07515	COG2226	methyltransferase
C7M21_RS07520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M21_RS07525	COG0322	excinuclease ABC activity
C7M21_RS07550	COG0789	Transcriptional regulator
C7M21_RS07555	COG2222	sugar isomerase
C7M21_RS07560	COG1653	transport
C7M21_RS07565	COG1175	transmembrane transport
C7M21_RS07570	COG0395	ABC-type sugar transport system, permease component
C7M21_RS07575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M21_RS07580	COG2188	Transcriptional regulator
C7M21_RS07585	COG3842	ATPase activity
C7M21_RS07590	COG2356	endonuclease I
C7M21_RS07595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M21_RS07600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M21_RS07605	COG2814	Major facilitator Superfamily
C7M21_RS07620	COG0457	Tetratricopeptide repeat
C7M21_RS07625	COG2508	Transcriptional regulator
C7M21_RS07640	COG1801	Protein of unknown function DUF72
C7M21_RS07645	COG0730	response to heat
C7M21_RS07650	COG0737	Belongs to the 5'-nucleotidase family
C7M21_RS07660	COG0739	heme binding
C7M21_RS07670	COG4470	Protein conserved in bacteria
C7M21_RS07675	COG2445	Protein of unknown function DUF86
C7M21_RS07680	COG0647	UMP catabolic process
C7M21_RS07685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M21_RS07690	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M21_RS07695	COG0460	homoserine dehydrogenase
C7M21_RS07700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M21_RS07710	COG0823	Involved in the tonB-independent uptake of proteins
C7M21_RS07710	COG4946	Tricorn protease homolog
C7M21_RS07710	COG1506	peptidase
C7M21_RS07715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M21_RS07720	COG4837	Protein of unknown function (DUF1462)
C7M21_RS07725	COG1252	NADH dehydrogenase
C7M21_RS07735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M21_RS07745	COG0316	Belongs to the HesB IscA family
C7M21_RS07750	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M21_RS07775	COG1131	(ABC) transporter
C7M21_RS07800	COG1252	NADH dehydrogenase
C7M21_RS07815	COG3584	3D domain protein
C7M21_RS07820	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M21_RS07830	COG2056	Na+-H+ antiporter family
C7M21_RS07835	COG1268	BioY protein
C7M21_RS07840	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M21_RS07845	COG2819	hydrolase of the alpha beta superfamily
C7M21_RS07850	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS07855	COG1169	isochorismate synthase
C7M21_RS07860	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M21_RS07865	COG3433	isochorismatase activity
C7M21_RS07865	COG1535	isochorismatase
C7M21_RS07870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS07875	COG3251	PFAM MbtH domain protein
C7M21_RS07880	COG5634	Uncharacterized conserved protein (DUF2278)
C7M21_RS07885	COG0686	Belongs to the AlaDH PNT family
C7M21_RS07890	COG2508	Transcriptional regulator
C7M21_RS07890	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M21_RS07895	COG4842	Belongs to the WXG100 family
C7M21_RS07900	COG5417	Belongs to the EsaB family
C7M21_RS07905	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M21_RS07910	COG1674	ftsk spoiiie
C7M21_RS07910	COG0433	COG0433 Predicted ATPase
C7M21_RS07915	COG1511	domain protein
C7M21_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS07930	COG1418	mRNA catabolic process
C7M21_RS07940	COG0628	permease
C7M21_RS07955	COG5506	Protein of unknown function (DUF1694)
C7M21_RS07960	COG1335	isochorismatase
C7M21_RS07965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M21_RS07970	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M21_RS07985	COG0142	geranyltranstransferase activity
C7M21_RS07995	COG4585	Histidine kinase
C7M21_RS08000	COG2197	response regulator
C7M21_RS08005	COG2050	protein possibly involved in aromatic compounds catabolism
C7M21_RS08010	COG1320	monovalent cation:proton antiporter activity
C7M21_RS08015	COG2212	antiporter activity
C7M21_RS08020	COG1863	multisubunit Na H antiporter MnhE subunit
C7M21_RS08025	COG0651	ATP synthesis coupled electron transport
C7M21_RS08030	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M21_RS08035	COG2111	Na H antiporter
C7M21_RS08040	COG2111	Na H antiporter
C7M21_RS08040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M21_RS08070	COG4565	transcriptional regulatory protein
C7M21_RS08075	COG3290	protein histidine kinase activity
C7M21_RS08085	COG3011	Protein conserved in bacteria
C7M21_RS08090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M21_RS08095	COG2814	Major facilitator Superfamily
C7M21_RS08100	COG5018	Exonuclease
C7M21_RS08110	COG2205	protein histidine kinase activity
C7M21_RS08115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M21_RS08125	COG2267	carboxylic ester hydrolase activity
C7M21_RS08130	COG1522	sequence-specific DNA binding
C7M21_RS08135	COG0436	Aminotransferase
C7M21_RS08140	COG1098	S1 RNA binding domain
C7M21_RS08145	COG2155	Conserved Protein
C7M21_RS08150	COG1979	alcohol dehydrogenase
C7M21_RS08155	COG1979	alcohol dehydrogenase
C7M21_RS08160	COG1335	isochorismatase
C7M21_RS08185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M21_RS08200	COG2738	Putative neutral zinc metallopeptidase
C7M21_RS08205	COG1253	flavin adenine dinucleotide binding
C7M21_RS08210	COG0366	Alpha amylase catalytic
C7M21_RS08215	COG0432	Pfam Uncharacterised protein family UPF0047
C7M21_RS08220	COG2070	2-Nitropropane dioxygenase
C7M21_RS08235	COG0840	transmembrane signaling receptor activity
C7M21_RS08240	COG0840	transmembrane signaling receptor activity
C7M21_RS08245	COG0840	transmembrane signaling receptor activity
C7M21_RS08250	COG0840	transmembrane signaling receptor activity
C7M21_RS08255	COG0693	protein deglycase activity
C7M21_RS08260	COG0673	inositol 2-dehydrogenase activity
C7M21_RS08265	COG0628	permease
C7M21_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M21_RS08290	COG1017	nitric oxide dioxygenase activity
C7M21_RS08295	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M21_RS08300	COG0569	domain protein
C7M21_RS08310	COG1510	regulation of RNA biosynthetic process
C7M21_RS08320	COG1454	alcohol dehydrogenase
C7M21_RS08330	COG2318	DinB family
C7M21_RS08335	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M21_RS08340	COG2268	Band 7 protein
C7M21_RS08345	COG3859	Proton-coupled thiamine transporter YuaJ
C7M21_RS08470	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M21_RS08475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M21_RS08480	COG1169	isochorismate synthase
C7M21_RS08490	COG0596	Alpha beta hydrolase
C7M21_RS08495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M21_RS08505	COG4948	Mandelate Racemase Muconate Lactonizing
C7M21_RS08515	COG1294	oxidase, subunit
C7M21_RS08520	COG1271	oxidase subunit
C7M21_RS08530	COG0288	reversible hydration of carbon dioxide
C7M21_RS08555	COG0783	Belongs to the Dps family
C7M21_RS08560	COG4824	toxin secretion phage lysis holin
C7M21_RS08565	COG0494	nUDIX hydrolase
C7M21_RS08570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M21_RS08575	COG1116	anion transmembrane transporter activity
C7M21_RS08580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M21_RS08585	COG1506	peptidase
C7M21_RS08605	COG0367	asparagine synthase
C7M21_RS08610	COG1113	amino acid transport
C7M21_RS08615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M21_RS08620	COG2267	carboxylic ester hydrolase activity
C7M21_RS08635	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M21_RS08640	COG1242	4 iron, 4 sulfur cluster binding
C7M21_RS08645	COG0477	Major facilitator Superfamily
C7M21_RS08660	COG1725	Transcriptional regulator
C7M21_RS08665	COG1131	(ABC) transporter
C7M21_RS08685	COG1136	(ABC) transporter
C7M21_RS08690	COG0577	efflux transmembrane transporter activity
C7M21_RS08695	COG0745	RESPONSE REGULATOR receiver
C7M21_RS08700	COG2205	protein histidine kinase activity
C7M21_RS08705	COG1136	(ABC) transporter
C7M21_RS08710	COG0577	efflux transmembrane transporter activity
C7M21_RS08715	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M21_RS08720	COG2814	Major facilitator Superfamily
C7M21_RS08725	COG2202	Pas domain
C7M21_RS08725	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS08740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M21_RS08750	COG1486	melibiose metabolic process
C7M21_RS08780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M21_RS08785	COG2081	HI0933 family
C7M21_RS08790	COG2244	polysaccharide biosynthetic process
C7M21_RS08795	COG1187	pseudouridine synthase activity
C7M21_RS08800	COG1349	DNA-binding transcription factor activity
C7M21_RS08805	COG1131	(ABC) transporter
C7M21_RS08810	COG4473	ABC transporter
C7M21_RS08815	COG2252	PERMEase
C7M21_RS08820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M21_RS08825	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M21_RS08830	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M21_RS08840	COG1597	lipid kinase activity
C7M21_RS08845	COG0510	thiamine kinase activity
C7M21_RS08860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS08865	COG0281	malic enzyme
C7M21_RS08870	COG5584	Small secreted protein
C7M21_RS08875	COG1363	Peptidase, m42
C7M21_RS08885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS08895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M21_RS08900	COG1674	ftsk spoiiie
C7M21_RS08910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M21_RS08915	COG4980	gas vesicle protein
C7M21_RS08920	COG3118	belongs to the thioredoxin family
C7M21_RS08925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M21_RS08925	COG1605	Chorismate mutase
C7M21_RS08930	COG1609	Transcriptional regulator
C7M21_RS08935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M21_RS08940	COG1360	Flagellar Motor Protein
C7M21_RS08945	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M21_RS08950	COG0517	IMP dehydrogenase activity
C7M21_RS08955	COG0454	-acetyltransferase
C7M21_RS08960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M21_RS08980	COG1378	Sugar-specific transcriptional regulator TrmB
C7M21_RS08985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M21_RS09000	COG0693	protein deglycase activity
C7M21_RS09015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M21_RS09015	COG1017	nitric oxide dioxygenase activity
C7M21_RS09020	COG0582	viral genome integration into host DNA
C7M21_RS09035	COG0457	Tetratricopeptide repeat
C7M21_RS09050	COG2199	diguanylate cyclase activity
C7M21_RS09050	COG2203	Gaf domain
C7M21_RS09055	COG1956	GAF domain-containing protein
C7M21_RS09060	COG1309	transcriptional regulator
C7M21_RS09065	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M21_RS09075	COG1114	Component of the transport system for branched-chain amino acids
C7M21_RS09080	COG1104	cysteine desulfurase activity
C7M21_RS09095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M21_RS09100	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M21_RS09105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M21_RS09110	COG0616	signal peptide processing
C7M21_RS09115	COG1714	RDD family
C7M21_RS09125	COG3874	Sporulation protein YtfJ
C7M21_RS09130	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M21_RS09135	COG0827	DNA restriction-modification system
C7M21_RS09145	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M21_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS09170	COG4109	DRTGG domain
C7M21_RS09180	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M21_RS09200	COG0587	DNA-directed DNA polymerase activity
C7M21_RS09205	COG0281	malic enzyme
C7M21_RS09225	COG0469	pyruvate kinase activity
C7M21_RS09230	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M21_RS09235	COG0628	permease
C7M21_RS09245	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS09260	COG0372	Belongs to the citrate synthase family
C7M21_RS09265	COG0538	isocitrate dehydrogenase activity
C7M21_RS09275	COG0745	RESPONSE REGULATOR receiver
C7M21_RS09280	COG5002	protein histidine kinase activity
C7M21_RS09285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M21_RS09285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M21_RS09290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M21_RS09295	COG1971	Probably functions as a manganese efflux pump
C7M21_RS09300	COG0237	dephospho-CoA kinase activity
C7M21_RS09305	COG0656	L-ascorbic acid biosynthetic process
C7M21_RS09310	COG2814	Major facilitator Superfamily
C7M21_RS09315	COG1733	regulation of RNA biosynthetic process
C7M21_RS09320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M21_RS09335	COG3611	Membrane attachment protein
C7M21_RS09340	COG1484	DNA-dependent DNA replication
C7M21_RS09345	COG0398	Pfam SNARE associated Golgi protein
C7M21_RS09365	COG3275	phosphorelay sensor kinase activity
C7M21_RS09370	COG3279	Response regulator of the LytR AlgR family
C7M21_RS09375	COG1380	Effector of murein hydrolase LrgA
C7M21_RS09380	COG1346	cytolysis
C7M21_RS09385	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M21_RS09400	COG3326	Membrane
C7M21_RS09410	COG1363	Peptidase, m42
C7M21_RS09415	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M21_RS09420	COG2160	L-arabinose isomerase activity
C7M21_RS09425	COG1069	ribulokinase activity
C7M21_RS09430	COG0235	Class ii aldolase
C7M21_RS09435	COG0647	UMP catabolic process
C7M21_RS09445	COG1653	transport
C7M21_RS09450	COG1175	transmembrane transport
C7M21_RS09455	COG0395	ABC-type sugar transport system, permease component
C7M21_RS09460	COG3534	alpha-L-arabinofuranosidase
C7M21_RS09465	COG1966	Carbon starvation protein
C7M21_RS09470	COG0247	lactate metabolic process
C7M21_RS09475	COG0277	FAD linked oxidase domain protein
C7M21_RS09480	COG3835	regulator
C7M21_RS09490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M21_RS09495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M21_RS09500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M21_RS09500	COG0072	phenylalanine-tRNA ligase activity
C7M21_RS09520	COG1286	toxin biosynthetic process
C7M21_RS09525	COG1796	DNA polymerase
C7M21_RS09525	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M21_RS09535	COG3766	membrane
C7M21_RS09545	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS09550	COG1309	transcriptional regulator
C7M21_RS09555	COG1024	Enoyl-CoA hydratase
C7M21_RS09560	COG2086	electron transfer activity
C7M21_RS09565	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M21_RS09570	COG3534	alpha-L-arabinofuranosidase
C7M21_RS09575	COG3118	belongs to the thioredoxin family
C7M21_RS09585	COG0527	aspartate kinase activity
C7M21_RS09590	COG1719	4-vinyl reductase, 4VR
C7M21_RS09595	COG2009	succinate dehydrogenase
C7M21_RS09600	COG1053	succinate dehydrogenase
C7M21_RS09605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M21_RS09610	COG0824	Thioesterase
C7M21_RS09615	COG2197	response regulator
C7M21_RS09620	COG1846	Transcriptional regulator
C7M21_RS09630	COG5401	PFAM Sporulation and spore germination
C7M21_RS09640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M21_RS09645	COG0622	Phosphoesterase
C7M21_RS09695	COG0028	Belongs to the TPP enzyme family
C7M21_RS09700	COG0440	acetolactate synthase activity
C7M21_RS09715	COG0473	3-isopropylmalate dehydrogenase activity
C7M21_RS09730	COG1477	protein flavinylation
C7M21_RS09730	COG0457	Tetratricopeptide repeat
C7M21_RS09745	COG0470	DNA polymerase III
C7M21_RS09745	COG1067	ATP-dependent peptidase activity
C7M21_RS09750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M21_RS09770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M21_RS09780	COG1587	Uroporphyrinogen-III synthase
C7M21_RS09785	COG0113	porphobilinogen synthase activity
C7M21_RS09795	COG1388	LysM domain
C7M21_RS09800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M21_RS09810	COG0525	valine-tRNA ligase activity
C7M21_RS09815	COG0285	dihydrofolate synthase activity
C7M21_RS09820	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M21_RS09840	COG1077	Cell shape determining protein MreB Mrl
C7M21_RS09845	COG1792	Involved in formation and maintenance of cell shape
C7M21_RS09850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M21_RS09860	COG2894	cell division
C7M21_RS09865	COG0739	heme binding
C7M21_RS09870	COG1994	Peptidase M50
C7M21_RS09880	COG2868	ribosomal protein
C7M21_RS09885	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M21_RS09890	COG3290	protein histidine kinase activity
C7M21_RS09905	COG0077	Prephenate dehydratase
C7M21_RS09910	COG1827	regulation of RNA biosynthetic process
C7M21_RS09915	COG1104	cysteine desulfurase activity
C7M21_RS09920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M21_RS09925	COG0157	Belongs to the NadC ModD family
C7M21_RS09935	COG1388	LysM domain
C7M21_RS09980	COG1862	Preprotein translocase
C7M21_RS09990	COG2323	membrane
C7M21_RS09995	COG2244	polysaccharide biosynthetic process
C7M21_RS10005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M21_RS10005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M21_RS10010	COG0490	domain, Protein
C7M21_RS10015	COG5416	Lipopolysaccharide assembly protein A domain
C7M21_RS10020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M21_RS10020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M21_RS10030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M21_RS10040	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS10040	COG3103	Sh3 type 3 domain protein
C7M21_RS10040	COG4991	sh3 domain protein
C7M21_RS10065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M21_RS10070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M21_RS10075	COG1959	2 iron, 2 sulfur cluster binding
C7M21_RS10080	COG1104	cysteine desulfurase activity
C7M21_RS10090	COG0457	Tetratricopeptide repeat
C7M21_RS10095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M21_RS10100	COG3881	PFAM PRC-barrel domain
C7M21_RS10115	COG0765	amino acid transport
C7M21_RS10120	COG0765	amino acid transport
C7M21_RS10125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS10130	COG1126	abc transporter atp-binding protein
C7M21_RS10135	COG0628	permease
C7M21_RS10160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M21_RS10190	COG0768	penicillin binding
C7M21_RS10215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M21_RS10220	COG0626	cystathionine gamma-synthase activity
C7M21_RS10230	COG2427	Protein of unknown function (DUF1641)
C7M21_RS10235	COG3383	formate dehydrogenase (NAD+) activity
C7M21_RS10240	COG5609	conserved protein (DUF2294)
C7M21_RS10245	COG2116	formate transmembrane transporter activity
C7M21_RS10255	COG2226	methyltransferase
C7M21_RS10260	COG1309	transcriptional regulator
C7M21_RS10265	COG2124	cytochrome p450
C7M21_RS10265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M21_RS10270	COG2814	Major facilitator Superfamily
C7M21_RS10275	COG0583	DNA-binding transcription factor activity
C7M21_RS10280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M21_RS10290	COG3711	transcriptional antiterminator
C7M21_RS10290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS10295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M21_RS10295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M21_RS10295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS10300	COG1482	cell wall glycoprotein biosynthetic process
C7M21_RS10315	COG0561	phosphatase activity
C7M21_RS10325	COG2318	DinB family
C7M21_RS10330	COG0456	acetyltransferase
C7M21_RS10345	COG0563	adenylate kinase activity
C7M21_RS10355	COG2207	Transcriptional regulator
C7M21_RS10355	COG3708	Transcriptional regulator
C7M21_RS10385	COG0398	Pfam SNARE associated Golgi protein
C7M21_RS10390	COG0726	polysaccharide deacetylase
C7M21_RS10395	COG2755	lipolytic protein G-D-S-L family
C7M21_RS10405	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M21_RS10410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M21_RS10415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M21_RS10420	COG1534	Rna-binding protein
C7M21_RS10430	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M21_RS10435	COG0799	negative regulation of ribosome biogenesis
C7M21_RS10440	COG2226	methyltransferase
C7M21_RS10445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M21_RS10450	COG1596	polysaccharide export
C7M21_RS10450	COG1555	photosystem II stabilization
C7M21_RS10455	COG2131	deaminase
C7M21_RS10460	COG2333	competence protein COMEC
C7M21_RS10460	COG0658	competence protein
C7M21_RS10475	COG1466	dna polymerase III delta subunit
C7M21_RS10490	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS10505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M21_RS10535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M21_RS10540	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M21_RS10545	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M21_RS10550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M21_RS10555	COG1610	YqeY-like protein
C7M21_RS10560	COG1030	water channel activity
C7M21_RS10565	COG4864	UPF0365 protein
C7M21_RS10580	COG0561	phosphatase activity
C7M21_RS10585	COG1702	phosphate starvation-inducible protein PhoH
C7M21_RS10590	COG1480	7TM receptor with intracellular HD hydrolase
C7M21_RS10600	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M21_RS10605	COG0295	cytidine deaminase activity
C7M21_RS10610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M21_RS10630	COG0751	glycine-tRNA ligase activity
C7M21_RS10635	COG0517	IMP dehydrogenase activity
C7M21_RS10650	COG0358	DNA primase activity
C7M21_RS10655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M21_RS10660	COG2010	Cytochrome c
C7M21_RS10665	COG2384	SAM-dependent methyltransferase
C7M21_RS10670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M21_RS10685	COG0513	Belongs to the DEAD box helicase family
C7M21_RS10700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS10705	COG0735	belongs to the Fur family
C7M21_RS10710	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M21_RS10715	COG4709	membrane
C7M21_RS10725	COG1388	LysM domain
C7M21_RS10730	COG5521	maltodextrose utilization protein MalA
C7M21_RS10735	COG2839	Protein conserved in bacteria
C7M21_RS10740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M21_RS10745	COG0477	Major facilitator Superfamily
C7M21_RS10755	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M21_RS10760	COG0573	inorganic phosphate transmembrane transporter activity
C7M21_RS10765	COG0581	inorganic phosphate transmembrane transporter activity
C7M21_RS10770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M21_RS10775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M21_RS10780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M21_RS10790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M21_RS10795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M21_RS10805	COG1757	Na H antiporter
C7M21_RS10810	COG4483	Protein conserved in bacteria
C7M21_RS10815	COG1940	carbohydrate kinase activity
C7M21_RS10820	COG2866	Carboxypeptidase
C7M21_RS10830	COG0011	TIGRFAM Protein of
C7M21_RS10840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS10850	COG1393	Belongs to the ArsC family
C7M21_RS10860	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS10865	COG1253	flavin adenine dinucleotide binding
C7M21_RS10870	COG0598	Magnesium transport protein CorA
C7M21_RS10875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M21_RS10880	COG1459	type II secretion system
C7M21_RS10885	COG4537	Required for transformation and DNA binding
C7M21_RS10890	COG4970	Tfp pilus assembly protein FimT
C7M21_RS10900	COG4940	Competence protein ComGF
C7M21_RS10925	COG0681	Belongs to the peptidase S26 family
C7M21_RS10935	COG1396	sequence-specific DNA binding
C7M21_RS10950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M21_RS10970	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M21_RS10985	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M21_RS10995	COG3872	metal-dependent enzyme
C7M21_RS11005	COG0006	proline dipeptidase activity
C7M21_RS11020	COG3854	ATPases associated with a variety of cellular activities
C7M21_RS11060	COG0511	ligase activity, forming carbon-carbon bonds
C7M21_RS11065	COG0439	Biotin carboxylase
C7M21_RS11070	COG1302	Protein conserved in bacteria
C7M21_RS11085	COG1570	exodeoxyribonuclease VII activity
C7M21_RS11095	COG0142	geranyltranstransferase activity
C7M21_RS11105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M21_RS11115	COG0497	DNA recombination
C7M21_RS11120	COG0750	zinc metalloprotease
C7M21_RS11125	COG0745	RESPONSE REGULATOR receiver
C7M21_RS11130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M21_RS11145	COG1902	pentaerythritol trinitrate reductase activity
C7M21_RS11165	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS11170	COG0584	glycerophosphoryl diester phosphodiesterase
C7M21_RS11175	COG0183	Belongs to the thiolase family
C7M21_RS11180	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M21_RS11185	COG1960	acyl-CoA dehydrogenase activity
C7M21_RS11190	COG0372	Belongs to the citrate synthase family
C7M21_RS11195	COG2079	MmgE PrpD family protein
C7M21_RS11200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M21_RS11210	COG3829	transcription factor binding
C7M21_RS11210	COG3290	protein histidine kinase activity
C7M21_RS11215	COG0280	phosphate acetyltransferase
C7M21_RS11220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M21_RS11225	COG3426	butyrate kinase activity
C7M21_RS11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M21_RS11235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M21_RS11240	COG0022	dehydrogenase e1 component
C7M21_RS11245	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M21_RS11250	COG1597	lipid kinase activity
C7M21_RS11260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M21_RS11265	COG0765	amino acid transport
C7M21_RS11270	COG1126	abc transporter atp-binding protein
C7M21_RS11275	COG4129	membrane
C7M21_RS11280	COG1376	ErfK ybiS ycfS ynhG family protein
C7M21_RS11290	COG0346	lactoylglutathione lyase activity
C7M21_RS11295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M21_RS11300	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M21_RS11305	COG0706	membrane insertase activity
C7M21_RS11320	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M21_RS11325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M21_RS11340	COG0596	Alpha beta hydrolase
C7M21_RS11360	COG0250	Participates in transcription elongation, termination and antitermination
C7M21_RS11365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M21_RS11365	COG2070	2-Nitropropane dioxygenase
C7M21_RS11380	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS11390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS11390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11390	COG3321	synthase
C7M21_RS11395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11395	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS11395	COG3321	synthase
C7M21_RS11395	COG0300	oxidoreductase activity
C7M21_RS11400	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11400	COG3321	synthase
C7M21_RS11400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS11400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS11405	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS11405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11405	COG0300	oxidoreductase activity
C7M21_RS11405	COG3321	synthase
C7M21_RS11410	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11410	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS11410	COG0300	oxidoreductase activity
C7M21_RS11410	COG3321	synthase
C7M21_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS11415	COG3321	synthase
C7M21_RS11415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS11415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS11420	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS11420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS11420	COG3321	synthase
C7M21_RS11420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS11425	COG2124	cytochrome p450
C7M21_RS11430	COG3425	synthase
C7M21_RS11435	COG1024	Enoyl-CoA hydratase
C7M21_RS11440	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M21_RS11445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS11450	COG0300	oxidoreductase activity
C7M21_RS11455	COG3048	D-serine ammonia-lyase activity
C7M21_RS11465	COG0346	lactoylglutathione lyase activity
C7M21_RS11475	COG0628	permease
C7M21_RS11490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M21_RS11495	COG0456	acetyltransferase
C7M21_RS11500	COG2329	Antibiotic biosynthesis monooxygenase
C7M21_RS11505	COG0456	acetyltransferase
C7M21_RS11505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M21_RS11510	COG4918	Iron-sulphur cluster biosynthesis
C7M21_RS11520	COG1073	alpha beta
C7M21_RS11530	COG0667	Aldo Keto reductase
C7M21_RS11540	COG0494	nUDIX hydrolase
C7M21_RS11545	COG1379	DNA repair
C7M21_RS11550	COG1396	sequence-specific DNA binding
C7M21_RS11555	COG0252	asparaginase activity
C7M21_RS11560	COG1027	Aspartate ammonia-lyase
C7M21_RS11565	COG1757	Na H antiporter
C7M21_RS11570	COG0281	malic enzyme
C7M21_RS11585	COG1300	Membrane
C7M21_RS11590	COG0735	belongs to the Fur family
C7M21_RS11600	COG4974	Belongs to the 'phage' integrase family
C7M21_RS11605	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M21_RS11610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M21_RS11615	COG1686	Belongs to the peptidase S11 family
C7M21_RS11620	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS11630	COG1191	sigma factor activity
C7M21_RS11650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M21_RS11665	COG0697	spore germination
C7M21_RS11670	COG0019	diaminopimelate decarboxylase activity
C7M21_RS11675	COG4086	secreted protein
C7M21_RS11680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M21_RS11690	COG0681	Belongs to the peptidase S26 family
C7M21_RS11700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M21_RS11700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M21_RS11705	COG0307	riboflavin synthase, alpha
C7M21_RS11720	COG0456	acetyltransferase
C7M21_RS11725	COG1547	Domain of unknown function (DUF309)
C7M21_RS11750	COG1686	Belongs to the peptidase S11 family
C7M21_RS11755	COG2715	membrane protein required for spore maturation
C7M21_RS11760	COG0700	Nucleoside recognition
C7M21_RS11765	COG1187	pseudouridine synthase activity
C7M21_RS11770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS11775	COG1333	cytochrome c biogenesis protein
C7M21_RS11780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M21_RS11785	COG0745	RESPONSE REGULATOR receiver
C7M21_RS11790	COG5002	protein histidine kinase activity
C7M21_RS11795	COG1595	DNA-templated transcription, initiation
C7M21_RS11805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M21_RS11810	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M21_RS11815	COG1141	Ferredoxin
C7M21_RS11820	COG4955	Helix-turn-helix domain
C7M21_RS11825	COG0514	ATP-dependent DNA helicase (RecQ)
C7M21_RS11830	COG1266	CAAX protease self-immunity
C7M21_RS11835	COG1388	LysM domain
C7M21_RS11845	COG1408	metallophosphoesterase
C7M21_RS11850	COG4862	establishment of competence for transformation
C7M21_RS11855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M21_RS11860	COG0492	ferredoxin-NADP+ reductase activity
C7M21_RS11865	COG2339	peptidase activity
C7M21_RS11870	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS11870	COG3773	Cell wall hydrolase
C7M21_RS11875	COG2959	enzyme of heme biosynthesis
C7M21_RS11880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M21_RS11895	COG0539	negative regulation of cytoplasmic translation
C7M21_RS11935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M21_RS11940	COG0776	regulation of translation
C7M21_RS11955	COG0142	geranyltranstransferase activity
C7M21_RS11965	COG0142	geranyltranstransferase activity
C7M21_RS11970	COG0105	UTP biosynthetic process
C7M21_RS11975	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M21_RS11990	COG4401	Chorismate mutase type I
C7M21_RS11995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M21_RS12030	COG0287	Prephenate dehydrogenase
C7M21_RS12045	COG0457	Tetratricopeptide repeat
C7M21_RS12060	COG0723	plastoquinol--plastocyanin reductase activity
C7M21_RS12065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M21_RS12070	COG2010	Cytochrome c
C7M21_RS12070	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M21_RS12075	COG4347	Protein of unknown function (DUF1405)
C7M21_RS12085	COG2140	Oxalate decarboxylase
C7M21_RS12090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS12095	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M21_RS12110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M21_RS12115	COG0438	transferase activity, transferring glycosyl groups
C7M21_RS12145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M21_RS12145	COG1199	ATP-dependent helicase activity
C7M21_RS12155	COG5353	protein conserved in bacteria
C7M21_RS12160	COG0436	Aminotransferase
C7M21_RS12170	COG3935	DnaD domain protein
C7M21_RS12175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M21_RS12185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M21_RS12185	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M21_RS12225	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M21_RS12230	COG2190	(PTS) system
C7M21_RS12235	COG1205	dead DEAH box helicase
C7M21_RS12235	COG1111	helicase
C7M21_RS12240	COG3359	exonuclease
C7M21_RS12270	COG0116	Belongs to the methyltransferase superfamily
C7M21_RS12285	COG1199	ATP-dependent helicase activity
C7M21_RS12290	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M21_RS12300	COG2233	PERMEase
C7M21_RS12310	COG1335	isochorismatase
C7M21_RS12315	COG2323	membrane
C7M21_RS12335	COG3424	synthase
C7M21_RS12340	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M21_RS12350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M21_RS12365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M21_RS12375	COG0328	RNA-DNA hybrid ribonuclease activity
C7M21_RS12380	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M21_RS12385	COG0328	RNA-DNA hybrid ribonuclease activity
C7M21_RS12405	COG1278	Cold shock
C7M21_RS12415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M21_RS12425	COG0386	Belongs to the glutathione peroxidase family
C7M21_RS12430	COG1418	mRNA catabolic process
C7M21_RS12435	COG1413	lyase activity
C7M21_RS12450	COG2136	Putative SAM-dependent methyltransferase
C7M21_RS12450	COG2521	methyltransferase
C7M21_RS12465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M21_RS12470	COG0204	Acyl-transferase
C7M21_RS12480	COG1272	protein, Hemolysin III
C7M21_RS12485	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M21_RS12490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M21_RS12500	COG1999	signal sequence binding
C7M21_RS12505	COG2755	lipolytic protein G-D-S-L family
C7M21_RS12510	COG4698	Protein conserved in bacteria
C7M21_RS12515	COG1846	Transcriptional regulator
C7M21_RS12535	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M21_RS12540	COG1525	nuclease
C7M21_RS12545	COG4282	regulation of fungal-type cell wall biogenesis
C7M21_RS12550	COG5444	nuclease activity
C7M21_RS12590	COG3391	amine dehydrogenase activity
C7M21_RS12605	COG0457	Tetratricopeptide repeat
C7M21_RS12630	COG3655	Transcriptional regulator
C7M21_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS12700	COG0457	Tetratricopeptide repeat
C7M21_RS12705	COG1388	LysM domain
C7M21_RS12730	COG1086	Polysaccharide biosynthesis protein
C7M21_RS12740	COG4641	Protein conserved in bacteria
C7M21_RS12755	COG0463	Glycosyl transferase, family 2
C7M21_RS12760	COG0456	acetyltransferase
C7M21_RS12770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7M21_RS12775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M21_RS12780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M21_RS12785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M21_RS12790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M21_RS12795	COG0456	acetyltransferase
C7M21_RS12800	COG1509	lysine 2,3-aminomutase activity
C7M21_RS12830	COG0671	phosphoesterase, PA-phosphatase related
C7M21_RS12850	COG1876	peptidase activity
C7M21_RS12860	COG2226	methyltransferase
C7M21_RS12865	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS12865	COG0793	Belongs to the peptidase S41A family
C7M21_RS12870	COG2188	Transcriptional regulator
C7M21_RS12875	COG2723	6-phospho-beta-galactosidase activity
C7M21_RS12885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M21_RS12895	COG0346	lactoylglutathione lyase activity
C7M21_RS12900	COG0400	carboxylic ester hydrolase activity
C7M21_RS12905	COG0778	Nitroreductase
C7M21_RS12910	COG1733	regulation of RNA biosynthetic process
C7M21_RS12920	COG1942	4-Oxalocrotonate Tautomerase
C7M21_RS12935	COG2962	Rard protein
C7M21_RS12945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M21_RS12950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M21_RS12955	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS12960	COG0534	Mate efflux family protein
C7M21_RS12965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M21_RS12970	COG1819	glycosyl
C7M21_RS12975	COG0791	NLP P60 protein
C7M21_RS12975	COG1388	LysM domain
C7M21_RS12980	COG2032	superoxide dismutase activity
C7M21_RS12985	COG0714	Associated with various cellular activities
C7M21_RS12990	COG4548	von Willebrand factor, type A
C7M21_RS13000	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M21_RS13005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS13010	COG0385	Bile acid
C7M21_RS13015	COG0733	neurotransmitter:sodium symporter activity
C7M21_RS13020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M21_RS13025	COG1657	PFAM Prenyltransferase squalene oxidase
C7M21_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS13060	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M21_RS13075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M21_RS13080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M21_RS13090	COG0514	ATP-dependent DNA helicase (RecQ)
C7M21_RS13095	COG1388	LysM domain
C7M21_RS13095	COG3584	3D domain protein
C7M21_RS13105	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M21_RS13120	COG2322	membrane
C7M21_RS13125	COG0741	lytic transglycosylase activity
C7M21_RS13130	COG0640	Transcriptional regulator
C7M21_RS13140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS13145	COG1309	transcriptional regulator
C7M21_RS13150	COG2207	Transcriptional regulator
C7M21_RS13150	COG0662	Cupin 2, conserved barrel domain protein
C7M21_RS13155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M21_RS13160	COG5444	nuclease activity
C7M21_RS13190	COG0243	molybdopterin cofactor binding
C7M21_RS13195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M21_RS13200	COG1070	Carbohydrate kinase
C7M21_RS13205	COG2814	Major facilitator Superfamily
C7M21_RS13215	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M21_RS13220	COG0300	oxidoreductase activity
C7M21_RS13240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M21_RS13245	COG0583	DNA-binding transcription factor activity
C7M21_RS13250	COG0070	glutamate synthase
C7M21_RS13250	COG0067	glutamate synthase
C7M21_RS13250	COG0069	glutamate synthase activity
C7M21_RS13255	COG0493	'glutamate synthase
C7M21_RS13260	COG0604	alcohol dehydrogenase
C7M21_RS13270	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M21_RS13275	COG0640	Transcriptional regulator
C7M21_RS13280	COG2814	Major facilitator Superfamily
C7M21_RS13285	COG0405	Gamma-glutamyltransferase
C7M21_RS13290	COG0166	Belongs to the GPI family
C7M21_RS13295	COG0582	viral genome integration into host DNA
C7M21_RS13310	COG0534	Mate efflux family protein
C7M21_RS13315	COG2017	converts alpha-aldose to the beta-anomer
C7M21_RS13320	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M21_RS13325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS13330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS13335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS13340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS13345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS13345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M21_RS13355	COG1649	PFAM Uncharacterised BCR, COG1649
C7M21_RS13360	COG1960	acyl-CoA dehydrogenase activity
C7M21_RS13365	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS13370	COG0439	Biotin carboxylase
C7M21_RS13375	COG0511	ligase activity, forming carbon-carbon bonds
C7M21_RS13380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M21_RS13385	COG1024	Enoyl-CoA hydratase
C7M21_RS13390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M21_RS13395	COG0586	Pfam SNARE associated Golgi protein
C7M21_RS13400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M21_RS13405	COG2246	polysaccharide biosynthetic process
C7M21_RS13415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M21_RS13430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M21_RS13435	COG2124	cytochrome p450
C7M21_RS13440	COG2610	gluconate transmembrane transporter activity
C7M21_RS13445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M21_RS13450	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M21_RS13455	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS13480	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M21_RS13490	COG0745	RESPONSE REGULATOR receiver
C7M21_RS13495	COG2205	protein histidine kinase activity
C7M21_RS13525	COG1136	(ABC) transporter
C7M21_RS13525	COG0577	efflux transmembrane transporter activity
C7M21_RS13550	COG2271	Major facilitator Superfamily
C7M21_RS13555	COG1609	Transcriptional regulator
C7M21_RS13560	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS13565	COG1312	Catalyzes the dehydration of D-mannonate
C7M21_RS13570	COG0800	Aldolase
C7M21_RS13575	COG1063	alcohol dehydrogenase
C7M21_RS13585	COG1115	amino acid carrier protein
C7M21_RS13595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M21_RS13600	COG0187	DNA topoisomerase II activity
C7M21_RS13605	COG1832	CoA-binding protein
C7M21_RS13615	COG4841	protein insertion into membrane
C7M21_RS13625	COG0824	Thioesterase
C7M21_RS13645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS13650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M21_RS13665	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M21_RS13675	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M21_RS13680	COG2201	protein-glutamate methylesterase activity
C7M21_RS13685	COG0785	Cytochrome C biogenesis protein
C7M21_RS13705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M21_RS13715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M21_RS13745	COG4195	phage-related replication protein
C7M21_RS13750	COG0756	dUTP diphosphatase activity
C7M21_RS13755	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M21_RS13770	COG3397	chitin binding
C7M21_RS13805	COG0456	acetyltransferase
C7M21_RS13830	COG1064	alcohol dehydrogenase
C7M21_RS13845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M21_RS13865	COG0574	Belongs to the PEP-utilizing enzyme family
C7M21_RS13865	COG3848	Pyruvate phosphate dikinase
C7M21_RS13870	COG1070	Carbohydrate kinase
C7M21_RS13885	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M21_RS13890	COG2211	Major facilitator Superfamily
C7M21_RS13900	COG0457	Tetratricopeptide repeat
C7M21_RS13905	COG0457	Tetratricopeptide repeat
C7M21_RS13935	COG0174	glutamine synthetase
C7M21_RS13940	COG0789	Transcriptional regulator
C7M21_RS13945	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M21_RS13950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M21_RS13955	COG0464	growth
C7M21_RS13965	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS13970	COG4112	unkown
C7M21_RS13975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M21_RS13980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M21_RS14020	COG2076	Multidrug Resistance protein
C7M21_RS14030	COG1764	response to oxidative stress
C7M21_RS14035	COG4195	phage-related replication protein
C7M21_RS14045	COG1404	Belongs to the peptidase S8 family
C7M21_RS14055	COG3619	membrane
C7M21_RS14060	COG3209	COG3209 Rhs family protein
C7M21_RS14065	COG2124	cytochrome p450
C7M21_RS14070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M21_RS14070	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M21_RS14070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14070	COG3321	synthase
C7M21_RS14075	COG4221	oxidoreductase activity
C7M21_RS14075	COG3321	synthase
C7M21_RS14075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS14080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS14080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS14080	COG3321	synthase
C7M21_RS14080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS14080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS14080	COG3321	synthase
C7M21_RS14085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14085	COG3321	synthase
C7M21_RS14085	COG0300	oxidoreductase activity
C7M21_RS14085	COG4221	oxidoreductase activity
C7M21_RS14090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS14090	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS14090	COG0300	oxidoreductase activity
C7M21_RS14090	COG3321	synthase
C7M21_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS14095	COG1024	Enoyl-CoA hydratase
C7M21_RS14100	COG1024	Enoyl-CoA hydratase
C7M21_RS14105	COG3425	synthase
C7M21_RS14110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14155	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M21_RS14175	COG2359	stage V sporulation protein S
C7M21_RS14180	COG1692	metallophosphoesterase
C7M21_RS14190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M21_RS14205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M21_RS14210	COG1426	Protein conserved in bacteria
C7M21_RS14225	COG0300	oxidoreductase activity
C7M21_RS14230	COG0612	Peptidase, M16
C7M21_RS14235	COG0612	Peptidase, M16
C7M21_RS14240	COG1033	growth of symbiont in host cell
C7M21_RS14240	COG2409	Drug exporters of the RND superfamily
C7M21_RS14245	COG1846	Transcriptional regulator
C7M21_RS14250	COG2814	Major facilitator Superfamily
C7M21_RS14255	COG2188	Transcriptional regulator
C7M21_RS14260	COG4980	gas vesicle protein
C7M21_RS14260	COG1674	ftsk spoiiie
C7M21_RS14270	COG0740	serine-type endopeptidase activity
C7M21_RS14275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M21_RS14285	COG0527	aspartate kinase activity
C7M21_RS14290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M21_RS14295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M21_RS14300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M21_RS14305	COG1873	PFAM PRC-barrel domain
C7M21_RS14310	COG0612	Peptidase, M16
C7M21_RS14315	COG0726	polysaccharide deacetylase
C7M21_RS14330	COG0196	riboflavin kinase activity
C7M21_RS14345	COG1550	Protein conserved in bacteria
C7M21_RS14355	COG1358	cellular component organization or biogenesis
C7M21_RS14360	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M21_RS14365	COG0195	Participates in both transcription termination and antitermination
C7M21_RS14375	COG2176	DNA-directed DNA polymerase activity
C7M21_RS14385	COG0750	zinc metalloprotease
C7M21_RS14395	COG4589	Belongs to the CDS family
C7M21_RS14400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M21_RS14430	COG1191	sigma factor activity
C7M21_RS14440	COG1776	CheC inhibitor of MCP methylation
C7M21_RS14445	COG0835	chemotaxis
C7M21_RS14450	COG0643	Histidine kinase
C7M21_RS14450	COG2198	Histidine kinase
C7M21_RS14455	COG2201	protein-glutamate methylesterase activity
C7M21_RS14460	COG0455	bacterial-type flagellum organization
C7M21_RS14465	COG1419	protein localization to endoplasmic reticulum
C7M21_RS14470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M21_RS14475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M21_RS14480	COG1684	flagellar biosynthetic protein fliR
C7M21_RS14485	COG1987	bacterial-type flagellum assembly
C7M21_RS14490	COG1338	Plays a role in the flagellum-specific transport system
C7M21_RS14495	COG3190	flagellar
C7M21_RS14500	COG2201	protein-glutamate methylesterase activity
C7M21_RS14505	COG1776	CheC inhibitor of MCP methylation
C7M21_RS14505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M21_RS14510	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M21_RS14515	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M21_RS14520	COG1582	Flagellar protein (FlbD)
C7M21_RS14525	COG4786	Flagellar basal body rod
C7M21_RS14530	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M21_RS14535	COG3144	bacterial-type flagellum assembly
C7M21_RS14540	COG3334	PFAM MgtE intracellular
C7M21_RS14545	COG2882	bacterial-type flagellum organization
C7M21_RS14550	COG1157	protein secretion by the type III secretion system
C7M21_RS14555	COG1317	bacterial-type flagellum organization
C7M21_RS14560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M21_RS14565	COG1766	The M ring may be actively involved in energy transduction
C7M21_RS14570	COG1677	Flagellar hook-basal body complex protein FliE
C7M21_RS14575	COG1558	bacterial-type flagellum-dependent cell motility
C7M21_RS14580	COG1815	bacterial-type flagellum-dependent cell motility
C7M21_RS14600	COG4974	Belongs to the 'phage' integrase family
C7M21_RS14610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M21_RS14615	COG0758	DNA mediated transformation
C7M21_RS14620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M21_RS14630	COG2257	FlhB HrpN YscU SpaS Family
C7M21_RS14645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M21_RS14670	COG1837	Belongs to the UPF0109 family
C7M21_RS14680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M21_RS14695	COG0552	protein localization to endoplasmic reticulum
C7M21_RS14700	COG1196	nuclear chromosome segregation
C7M21_RS14710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS14715	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS14720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M21_RS14735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M21_RS14740	COG1760	l-serine dehydratase
C7M21_RS14745	COG1760	l-serine dehydratase
C7M21_RS14750	COG1461	Dihydroxyacetone kinase
C7M21_RS14755	COG1302	Protein conserved in bacteria
C7M21_RS14770	COG1564	THIamine pyrophosphokinase
C7M21_RS14775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M21_RS14785	COG2815	serine threonine protein kinase
C7M21_RS14785	COG0515	serine threonine protein kinase
C7M21_RS14790	COG0631	protein serine/threonine phosphatase activity
C7M21_RS14800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M21_RS14800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M21_RS14810	COG0242	peptide deformylase activity
C7M21_RS14815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M21_RS14820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M21_RS14830	COG0194	GDP metabolic process
C7M21_RS14835	COG2052	Domain of unknown function (DUF370)
C7M21_RS14840	COG1561	YicC-like family, N-terminal region
C7M21_RS14845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M21_RS14855	COG1648	precorrin-2 dehydrogenase activity
C7M21_RS14860	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M21_RS14865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M21_RS14880	COG0306	phosphate transporter
C7M21_RS14890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M21_RS14895	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M21_RS14910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M21_RS14915	COG0505	Belongs to the CarA family
C7M21_RS14920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M21_RS14930	COG2233	PERMEase
C7M21_RS14940	COG0564	pseudouridine synthase activity
C7M21_RS14950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M21_RS14955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M21_RS14960	COG3599	regulation of cell shape
C7M21_RS14965	COG2302	S4 RNA-binding domain
C7M21_RS14970	COG0762	integral membrane protein
C7M21_RS14980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M21_RS14990	COG1873	PFAM PRC-barrel domain
C7M21_RS14995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M21_RS15000	COG1119	ATPase activity
C7M21_RS15005	COG1191	sigma factor activity
C7M21_RS15010	COG1191	sigma factor activity
C7M21_RS15020	COG4412	M6 family metalloprotease domain protein
C7M21_RS15020	COG1404	Belongs to the peptidase S8 family
C7M21_RS15025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M21_RS15030	COG0849	cell division
C7M21_RS15035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M21_RS15050	COG0772	Belongs to the SEDS family
C7M21_RS15070	COG0768	penicillin binding
C7M21_RS15080	COG4839	cell division protein FtsL
C7M21_RS15100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M21_RS15115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M21_RS15120	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M21_RS15130	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M21_RS15135	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M21_RS15140	COG3314	Sporulation integral membrane protein YlbJ
C7M21_RS15150	COG0742	ribosomal rna small subunit methyltransferase
C7M21_RS15160	COG3679	Belongs to the UPF0342 family
C7M21_RS15175	COG2340	Cysteine-rich secretory protein family
C7M21_RS15180	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M21_RS15190	COG3336	cytochrome c oxidase
C7M21_RS15195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M21_RS15200	COG1845	cytochrome c oxidase, subunit III
C7M21_RS15205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M21_RS15210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M21_RS15210	COG2010	Cytochrome c
C7M21_RS15225	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M21_RS15230	COG0772	Belongs to the SEDS family
C7M21_RS15240	COG2066	Belongs to the glutaminase family
C7M21_RS15245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M21_RS15250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M21_RS15260	COG4896	Protein conserved in bacteria
C7M21_RS15290	COG1595	DNA-templated transcription, initiation
C7M21_RS15295	COG3227	Zinc metalloprotease (Elastase)
C7M21_RS15305	COG0483	inositol monophosphate 1-phosphatase activity
C7M21_RS15325	COG1982	Orn Lys Arg decarboxylase major
C7M21_RS15340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS15345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M21_RS15350	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M21_RS15355	COG0022	dehydrogenase e1 component
C7M21_RS15360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M21_RS15365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M21_RS15370	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS15370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS15370	COG4221	oxidoreductase activity
C7M21_RS15370	COG3321	synthase
C7M21_RS15375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS15375	COG0300	oxidoreductase activity
C7M21_RS15375	COG3321	synthase
C7M21_RS15375	COG4221	oxidoreductase activity
C7M21_RS15380	COG4221	oxidoreductase activity
C7M21_RS15380	COG0300	oxidoreductase activity
C7M21_RS15380	COG3321	synthase
C7M21_RS15380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS15385	COG0300	oxidoreductase activity
C7M21_RS15385	COG3321	synthase
C7M21_RS15385	COG4221	oxidoreductase activity
C7M21_RS15385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS15390	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS15390	COG3321	synthase
C7M21_RS15390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS15390	COG4221	oxidoreductase activity
C7M21_RS15395	COG4221	oxidoreductase activity
C7M21_RS15395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M21_RS15395	COG0300	oxidoreductase activity
C7M21_RS15395	COG3321	synthase
C7M21_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS15400	COG4221	oxidoreductase activity
C7M21_RS15400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M21_RS15400	COG3321	synthase
C7M21_RS15410	COG0497	DNA recombination
C7M21_RS15420	COG0242	peptide deformylase activity
C7M21_RS15425	COG0561	phosphatase activity
C7M21_RS15435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M21_RS15445	COG0569	domain protein
C7M21_RS15450	COG2105	PFAM AIG2 family protein
C7M21_RS15450	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M21_RS15455	COG3852	Histidine kinase
C7M21_RS15460	COG2002	toxin-antitoxin pair type II binding
C7M21_RS15465	COG1077	Cell shape determining protein MreB Mrl
C7M21_RS15475	COG2309	aminopeptidase activity
C7M21_RS15480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M21_RS15485	COG0488	(ABC) transporter
C7M21_RS15495	COG0681	Belongs to the peptidase S26 family
C7M21_RS15500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M21_RS15500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M21_RS15500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS15505	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M21_RS15510	COG1349	DNA-binding transcription factor activity
C7M21_RS15515	COG0577	efflux transmembrane transporter activity
C7M21_RS15520	COG1136	(ABC) transporter
C7M21_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M21_RS15535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M21_RS15540	COG0314	molybdopterin synthase activity
C7M21_RS15545	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M21_RS15550	COG0303	'Molybdopterin
C7M21_RS15555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M21_RS15575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS15580	COG0668	transmembrane transport
C7M21_RS15600	COG0716	FMN binding
C7M21_RS15610	COG0716	FMN binding
C7M21_RS15615	COG0583	DNA-binding transcription factor activity
C7M21_RS15620	COG0517	IMP dehydrogenase activity
C7M21_RS15630	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M21_RS15635	COG4703	Protein of unknown function (DUF1797)
C7M21_RS15640	COG2200	EAL domain
C7M21_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS15655	COG1408	metallophosphoesterase
C7M21_RS15660	COG1376	ErfK ybiS ycfS ynhG family protein
C7M21_RS15665	COG2814	Major facilitator Superfamily
C7M21_RS15675	COG0835	chemotaxis
C7M21_RS15675	COG0784	Response regulator, receiver
C7M21_RS15680	COG0436	Aminotransferase
C7M21_RS15685	COG4191	Histidine kinase
C7M21_RS15690	COG0768	penicillin binding
C7M21_RS15695	COG2340	Cysteine-rich secretory protein family
C7M21_RS15700	COG2084	Dehydrogenase
C7M21_RS15705	COG0840	transmembrane signaling receptor activity
C7M21_RS15710	COG1533	DNA photolyase activity
C7M21_RS15720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M21_RS15725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M21_RS15730	COG1263	PTS System
C7M21_RS15730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS15730	COG2190	(PTS) system
C7M21_RS15735	COG3711	transcriptional antiterminator
C7M21_RS15740	COG1609	Transcriptional regulator
C7M21_RS15745	COG0006	proline dipeptidase activity
C7M21_RS15750	COG2217	Heavy metal translocating P-type atpase
C7M21_RS15755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M21_RS15760	COG2244	polysaccharide biosynthetic process
C7M21_RS15765	COG3773	Cell wall hydrolase
C7M21_RS15775	COG4873	Protein conserved in bacteria
C7M21_RS15790	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS15795	COG1733	regulation of RNA biosynthetic process
C7M21_RS15805	COG0602	queuosine metabolic process
C7M21_RS15810	COG0720	synthase
C7M21_RS15825	COG3949	Membrane
C7M21_RS15830	COG0542	response to heat
C7M21_RS15835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M21_RS15840	COG1360	Flagellar Motor Protein
C7M21_RS15845	COG1846	Transcriptional regulator
C7M21_RS15850	COG3852	Histidine kinase
C7M21_RS15880	COG0436	Aminotransferase
C7M21_RS15885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M21_RS15900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M21_RS15905	COG5002	protein histidine kinase activity
C7M21_RS15910	COG3594	Acyltransferase
C7M21_RS15920	COG2323	membrane
C7M21_RS15925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M21_RS15955	COG1191	sigma factor activity
C7M21_RS15960	COG0861	Integral membrane protein TerC family
C7M21_RS15965	COG0586	Pfam SNARE associated Golgi protein
C7M21_RS15970	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M21_RS15975	COG3285	dna ligase
C7M21_RS15975	COG1793	dna ligase
C7M21_RS15980	COG0726	polysaccharide deacetylase
C7M21_RS15985	COG1846	Transcriptional regulator
C7M21_RS16000	COG0789	Transcriptional regulator
C7M21_RS16005	COG2239	Acts as a magnesium transporter
C7M21_RS16020	COG1388	LysM domain
C7M21_RS16020	COG3858	chitin binding
C7M21_RS16025	COG4721	ABC-type cobalt transport system, permease component
C7M21_RS16030	COG1122	ATPase activity
C7M21_RS16035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M21_RS16040	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS16045	COG1404	Belongs to the peptidase S8 family
C7M21_RS16055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M21_RS16060	COG2814	Major facilitator Superfamily
C7M21_RS16070	COG0463	Glycosyl transferase, family 2
C7M21_RS16070	COG0457	Tetratricopeptide repeat
C7M21_RS16085	COG1764	response to oxidative stress
C7M21_RS16090	COG1846	Transcriptional regulator
C7M21_RS16095	COG1764	response to oxidative stress
C7M21_RS16105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M21_RS16110	COG0788	formyltetrahydrofolate deformylase activity
C7M21_RS16115	COG2076	Multidrug Resistance protein
C7M21_RS16120	COG2076	Multidrug Resistance protein
C7M21_RS16125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M21_RS16130	COG1607	acyl-coa hydrolase
C7M21_RS16135	COG1834	amidinotransferase
C7M21_RS16140	COG2706	6-phosphogluconolactonase activity
C7M21_RS16145	COG4608	Belongs to the ABC transporter superfamily
C7M21_RS16150	COG0791	NLP P60 protein
C7M21_RS16155	COG4948	Mandelate Racemase Muconate Lactonizing
C7M21_RS16160	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M21_RS16165	COG4166	transmembrane transport
C7M21_RS16170	COG0444	Belongs to the ABC transporter superfamily
C7M21_RS16175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M21_RS16180	COG0601	transmembrane transport
C7M21_RS16185	COG2362	D-Aminopeptidase
C7M21_RS16190	COG0477	Major facilitator Superfamily
C7M21_RS16195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M21_RS16200	COG0463	Glycosyl transferase, family 2
C7M21_RS16205	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M21_RS16210	COG0346	lactoylglutathione lyase activity
C7M21_RS16215	COG0531	amino acid
C7M21_RS16220	COG1392	Phosphate transport regulator
C7M21_RS16225	COG0306	phosphate transporter
C7M21_RS16240	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS16240	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS16280	COG3778	Protein conserved in bacteria
C7M21_RS16285	COG3299	homolog of phage Mu protein gp47
C7M21_RS16290	COG3628	GPW Gp25 family protein
C7M21_RS16300	COG4193	domain, Protein
C7M21_RS16305	COG1652	LysM domain
C7M21_RS16310	COG3953	SLT domain
C7M21_RS16310	COG3953	SLT domain
C7M21_RS16310	COG5412	phage tail tape measure protein
C7M21_RS16310	COG5412	phage tail tape measure protein
C7M21_RS16310	COG3953	SLT domain
C7M21_RS16310	COG5412	phage tail tape measure protein
C7M21_RS16360	COG4653	Phage capsid family
C7M21_RS16365	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M21_RS16370	COG5518	Phage portal protein
C7M21_RS16375	COG1783	phage Terminase large subunit
C7M21_RS16380	COG3728	DNA packaging
C7M21_RS16380	COG5484	DNA packaging
C7M21_RS16385	COG1595	DNA-templated transcription, initiation
C7M21_RS16400	COG1484	DNA-dependent DNA replication
C7M21_RS16405	COG1522	sequence-specific DNA binding
C7M21_RS16415	COG1396	sequence-specific DNA binding
C7M21_RS16420	COG2856	Zn peptidase
C7M21_RS16425	COG4195	phage-related replication protein
C7M21_RS16435	COG1388	LysM domain
C7M21_RS16435	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M21_RS16435	COG3409	Peptidoglycan-binding domain 1 protein
C7M21_RS16445	COG0457	Tetratricopeptide repeat
C7M21_RS16450	COG2318	DinB family
C7M21_RS16455	COG0730	response to heat
C7M21_RS16465	COG1131	(ABC) transporter
C7M21_RS16470	COG2205	protein histidine kinase activity
C7M21_RS16470	COG2770	Histidine kinase
C7M21_RS16475	COG0745	RESPONSE REGULATOR receiver
C7M21_RS16480	COG2721	sulfolactate sulfo-lyase activity
C7M21_RS16485	COG0246	Mannitol dehydrogenase
C7M21_RS16490	COG1609	Transcriptional regulator
C7M21_RS16495	COG2211	Major facilitator Superfamily
C7M21_RS16505	COG1252	NADH dehydrogenase
C7M21_RS16515	COG4297	protein containing double-stranded beta helix domain
C7M21_RS16520	COG0697	spore germination
C7M21_RS16525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M21_RS16530	COG0390	transport system, permease component
C7M21_RS16535	COG1587	Uroporphyrinogen-III synthase
C7M21_RS16545	COG1819	glycosyl
C7M21_RS16550	COG2124	cytochrome p450
C7M21_RS16555	COG2427	Protein of unknown function (DUF1641)
C7M21_RS16560	COG3383	formate dehydrogenase (NAD+) activity
C7M21_RS16570	COG2205	protein histidine kinase activity
C7M21_RS16585	COG1285	pathogenesis
C7M21_RS16615	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M21_RS16620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS16620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M21_RS16625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M21_RS16630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M21_RS16635	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M21_RS16645	COG1846	Transcriptional regulator
C7M21_RS16655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M21_RS16660	COG2367	Beta-lactamase
C7M21_RS16665	COG0346	lactoylglutathione lyase activity
C7M21_RS16675	COG5444	nuclease activity
C7M21_RS16805	COG4974	Belongs to the 'phage' integrase family
C7M21_RS16825	COG0626	cystathionine gamma-synthase activity
C7M21_RS16830	COG0626	cystathionine gamma-synthase activity
C7M21_RS16835	COG2382	esterase
C7M21_RS16845	COG2153	protein acetylation
C7M21_RS16855	COG1131	(ABC) transporter
C7M21_RS16875	COG0210	DNA helicase
C7M21_RS16930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M21_RS16935	COG0351	phosphomethylpyrimidine kinase
C7M21_RS16940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M21_RS16950	COG2104	thiamine diphosphate biosynthetic process
C7M21_RS16955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M21_RS16960	COG0352	thiamine-phosphate diphosphorylase activity
C7M21_RS16965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M21_RS16970	COG0475	glutathione-regulated potassium exporter activity
C7M21_RS16970	COG0569	domain protein
C7M21_RS16980	COG0564	pseudouridine synthase activity
C7M21_RS16985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M21_RS16990	COG2357	RelA SpoT domain protein
C7M21_RS17000	COG4116	CYTH
C7M21_RS17005	COG0741	lytic transglycosylase activity
C7M21_RS17010	COG2346	COG2346, Truncated hemoglobins
C7M21_RS17020	COG1164	Oligoendopeptidase f
C7M21_RS17025	COG4469	Competence protein
C7M21_RS17030	COG4862	establishment of competence for transformation
C7M21_RS17035	COG0861	Integral membrane protein TerC family
C7M21_RS17040	COG1393	Belongs to the ArsC family
C7M21_RS17045	COG0456	acetyltransferase
C7M21_RS17055	COG4608	Belongs to the ABC transporter superfamily
C7M21_RS17060	COG0444	Belongs to the ABC transporter superfamily
C7M21_RS17065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M21_RS17070	COG0601	transmembrane transport
C7M21_RS17075	COG4166	transmembrane transport
C7M21_RS17080	COG0180	Tryptophanyl-tRNA synthetase
C7M21_RS17090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M21_RS17095	COG0601	transmembrane transport
C7M21_RS17105	COG4608	Belongs to the ABC transporter superfamily
C7M21_RS17110	COG0444	Belongs to the ABC transporter superfamily
C7M21_RS17115	COG5504	Zn-dependent protease
C7M21_RS17120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M21_RS17125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M21_RS17140	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M21_RS17150	COG2267	carboxylic ester hydrolase activity
C7M21_RS17165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M21_RS17170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M21_RS17175	COG0505	Belongs to the CarA family
C7M21_RS17180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M21_RS17200	COG2271	Major facilitator Superfamily
C7M21_RS17205	COG0277	FAD linked oxidase domain protein
C7M21_RS17215	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M21_RS17220	COG1073	alpha beta
C7M21_RS17225	COG0561	phosphatase activity
C7M21_RS17240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M21_RS17245	COG1307	EDD domain protein, DegV family
C7M21_RS17255	COG2124	cytochrome p450
C7M21_RS17260	COG0840	transmembrane signaling receptor activity
C7M21_RS17270	COG2996	Protein conserved in bacteria
C7M21_RS17280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M21_RS17280	COG0646	methionine synthase
C7M21_RS17285	COG2153	protein acetylation
C7M21_RS17290	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M21_RS17295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M21_RS17300	COG1279	arginine transmembrane transporter activity
C7M21_RS17305	COG2318	DinB family
C7M21_RS17310	COG2207	Transcriptional regulator
C7M21_RS17310	COG1917	Cupin 2, conserved barrel domain protein
C7M21_RS17315	COG0534	Mate efflux family protein
C7M21_RS17320	COG1562	ergosterol biosynthetic process
C7M21_RS17325	COG0367	asparagine synthase
C7M21_RS17340	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M21_RS17380	COG1403	HNH endonuclease
C7M21_RS17385	COG0419	ATPase involved in DNA repair
C7M21_RS17390	COG0420	3'-5' exonuclease activity
C7M21_RS17405	COG2323	membrane
C7M21_RS17410	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M21_RS17420	COG2814	Major facilitator Superfamily
C7M21_RS17425	COG3180	Ammonia monooxygenase
C7M21_RS17430	COG1846	Transcriptional regulator
C7M21_RS17435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M21_RS17440	COG0681	Belongs to the peptidase S26 family
C7M21_RS17445	COG0398	Pfam SNARE associated Golgi protein
C7M21_RS17460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M21_RS17485	COG5646	InterPro IPR014922
C7M21_RS17495	COG4903	ComK protein
C7M21_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS17510	COG0723	plastoquinol--plastocyanin reductase activity
C7M21_RS17510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M21_RS17515	COG0840	transmembrane signaling receptor activity
C7M21_RS17520	COG1268	BioY protein
C7M21_RS17525	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS17530	COG0183	Belongs to the thiolase family
C7M21_RS17535	COG0406	alpha-ribazole phosphatase activity
C7M21_RS17540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M21_RS17550	COG1404	Belongs to the peptidase S8 family
C7M21_RS17555	COG0501	Belongs to the peptidase M48B family
C7M21_RS17565	COG0318	PFAM AMP-dependent synthetase and ligase
C7M21_RS17570	COG0702	epimerase
C7M21_RS17575	COG0095	Lipoate-protein ligase
C7M21_RS17580	COG1234	tRNA 3'-trailer cleavage
C7M21_RS17590	COG1301	dicarboxylic acid transport
C7M21_RS17595	COG1363	Peptidase, m42
C7M21_RS17605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M21_RS17610	COG1511	domain protein
C7M21_RS17615	COG1309	transcriptional regulator
C7M21_RS17635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M21_RS17640	COG2329	Antibiotic biosynthesis monooxygenase
C7M21_RS17645	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M21_RS17650	COG1473	amidohydrolase
C7M21_RS17660	COG4473	ABC transporter
C7M21_RS17665	COG1131	(ABC) transporter
C7M21_RS17670	COG0537	adenosine 5'-monophosphoramidase activity
C7M21_RS17675	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M21_RS17690	COG4980	gas vesicle protein
C7M21_RS17725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M21_RS17740	COG4717	serine-type aminopeptidase activity
C7M21_RS17745	COG0420	3'-5' exonuclease activity
C7M21_RS17750	COG1668	transmembrane transport
C7M21_RS17755	COG4152	abc transporter atp-binding protein
C7M21_RS17765	COG1024	Enoyl-CoA hydratase
C7M21_RS17775	COG0490	domain, Protein
C7M21_RS17780	COG0475	glutathione-regulated potassium exporter activity
C7M21_RS17790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M21_RS17795	COG0561	phosphatase activity
C7M21_RS17800	COG4335	DNA alkylation repair
C7M21_RS17815	COG0189	ligase activity
C7M21_RS17820	COG0189	ligase activity
C7M21_RS17835	COG0702	epimerase
C7M21_RS17840	COG1132	(ABC) transporter
C7M21_RS17845	COG1132	(ABC) transporter
C7M21_RS17850	COG0589	response to stress
C7M21_RS17860	COG3226	Transcriptional regulator
C7M21_RS17865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M21_RS17870	COG0726	polysaccharide deacetylase
C7M21_RS17875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M21_RS17880	COG0668	transmembrane transport
C7M21_RS17890	COG0584	glycerophosphoryl diester phosphodiesterase
C7M21_RS17895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M21_RS17900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M21_RS17905	COG1253	flavin adenine dinucleotide binding
C7M21_RS17910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M21_RS17915	COG0436	Aminotransferase
C7M21_RS17920	COG0789	Transcriptional regulator
C7M21_RS17925	COG1253	flavin adenine dinucleotide binding
C7M21_RS17930	COG0204	Acyl-transferase
C7M21_RS17935	COG1595	DNA-templated transcription, initiation
C7M21_RS17950	COG0733	neurotransmitter:sodium symporter activity
C7M21_RS17955	COG0531	amino acid
C7M21_RS17960	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS17965	COG0372	Belongs to the citrate synthase family
C7M21_RS17970	COG0583	DNA-binding transcription factor activity
C7M21_RS17975	COG1388	LysM domain
C7M21_RS17975	COG0791	NLP P60 protein
C7M21_RS17980	COG1785	Belongs to the alkaline phosphatase family
C7M21_RS17985	COG2719	SpoVR family
C7M21_RS17990	COG0668	transmembrane transport
C7M21_RS17995	COG1959	2 iron, 2 sulfur cluster binding
C7M21_RS18000	COG0791	NLP P60 protein
C7M21_RS18000	COG1388	LysM domain
C7M21_RS18015	COG0431	NADPH-dependent FMN reductase
C7M21_RS18020	COG2197	response regulator
C7M21_RS18025	COG4585	Histidine kinase
C7M21_RS18025	COG2203	Gaf domain
C7M21_RS18030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M21_RS18035	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M21_RS18045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M21_RS18050	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M21_RS18055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M21_RS18060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M21_RS18060	COG3153	acetyltransferase
C7M21_RS18065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M21_RS18070	COG0517	IMP dehydrogenase activity
C7M21_RS18080	COG0564	pseudouridine synthase activity
C7M21_RS18085	COG3764	Sortase (surface protein transpeptidase)
C7M21_RS18090	COG1525	nuclease
C7M21_RS18090	COG4085	toxin activity
C7M21_RS18090	COG0737	Belongs to the 5'-nucleotidase family
C7M21_RS18095	COG5577	PFAM Coat F domain
C7M21_RS18115	COG1823	symporter activity
C7M21_RS18120	COG3706	GGDEF domain
C7M21_RS18125	COG1464	Belongs to the NlpA lipoprotein family
C7M21_RS18130	COG1278	Cold shock
C7M21_RS18135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M21_RS18140	COG1131	(ABC) transporter
C7M21_RS18145	COG1131	(ABC) transporter
C7M21_RS18150	COG1725	Transcriptional regulator
C7M21_RS18165	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M21_RS18170	COG2814	Major facilitator Superfamily
C7M21_RS18175	COG1566	PFAM secretion protein HlyD family protein
C7M21_RS18180	COG1846	Transcriptional regulator
C7M21_RS18190	COG2766	serine protein kinase
C7M21_RS18195	COG1664	Polymer-forming cytoskeletal
C7M21_RS18200	COG1664	Polymer-forming cytoskeletal
C7M21_RS18205	COG0789	Transcriptional regulator
C7M21_RS18210	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M21_RS18220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M21_RS18225	COG3382	B3 4 domain protein
C7M21_RS18235	COG1476	TRANSCRIPTIONal
C7M21_RS18255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M21_RS18260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M21_RS18265	COG1116	anion transmembrane transporter activity
C7M21_RS18275	COG0753	catalase activity
C7M21_RS18280	COG4608	Belongs to the ABC transporter superfamily
C7M21_RS18285	COG0444	Belongs to the ABC transporter superfamily
C7M21_RS18290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M21_RS18295	COG0601	transmembrane transport
C7M21_RS18300	COG0747	negative chemotaxis
C7M21_RS18310	COG0277	FAD linked oxidase domain protein
C7M21_RS18320	COG3340	Belongs to the peptidase S51 family
C7M21_RS18325	COG1757	Na H antiporter
C7M21_RS18435	COG0735	belongs to the Fur family
C7M21_RS18440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M21_RS18450	COG4129	membrane
C7M21_RS18455	COG1132	(ABC) transporter
C7M21_RS18475	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS18485	COG1194	a g-specific adenine glycosylase
C7M21_RS18490	COG1988	membrane-bound metal-dependent
C7M21_RS18495	COG4485	Bacterial membrane protein, YfhO
C7M21_RS18500	COG0463	Glycosyl transferase, family 2
C7M21_RS18505	COG0596	Alpha beta hydrolase
C7M21_RS18510	COG5658	integral membrane protein
C7M21_RS18515	COG3103	Sh3 type 3 domain protein
C7M21_RS18530	COG3591	Belongs to the peptidase S1B family
C7M21_RS18540	COG2814	Major facilitator Superfamily
C7M21_RS18555	COG1090	epimerase
C7M21_RS18570	COG0778	Nitroreductase
C7M21_RS18575	COG0384	phenazine biosynthesis protein PhzF
C7M21_RS18580	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M21_RS18580	COG0392	lysyltransferase activity
C7M21_RS18585	COG1846	Transcriptional regulator
C7M21_RS18590	COG2814	Major facilitator Superfamily
C7M21_RS18595	COG2318	DinB family
C7M21_RS18600	COG2732	(Barnase) inhibitor
C7M21_RS18605	COG0574	Belongs to the PEP-utilizing enzyme family
C7M21_RS18605	COG3848	Pyruvate phosphate dikinase
C7M21_RS18610	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M21_RS18615	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M21_RS18620	COG1695	Transcriptional regulator
C7M21_RS18630	COG2514	catechol 2,3-dioxygenase activity
C7M21_RS18635	COG2259	Doxx family
C7M21_RS18640	COG1132	(ABC) transporter
C7M21_RS18645	COG1132	(ABC) transporter
C7M21_RS18650	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M21_RS18655	COG1263	PTS System
C7M21_RS18655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS18660	COG1737	Transcriptional regulator
C7M21_RS18665	COG1486	melibiose metabolic process
C7M21_RS18675	COG3284	Transcriptional regulator
C7M21_RS18680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M21_RS18685	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M21_RS18690	COG0022	dehydrogenase e1 component
C7M21_RS18695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M21_RS18700	COG4637	Psort location Cytoplasmic, score
C7M21_RS18705	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M21_RS18715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M21_RS18720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M21_RS18725	COG0598	Magnesium transport protein CorA
C7M21_RS18735	COG2084	Dehydrogenase
C7M21_RS18740	COG0726	polysaccharide deacetylase
C7M21_RS18750	COG0535	radical SAM domain protein
C7M21_RS18755	COG0668	transmembrane transport
C7M21_RS18765	COG0387	Pfam Sodium calcium exchanger
C7M21_RS18780	COG1295	ribonuclease BN
C7M21_RS18785	COG4980	gas vesicle protein
C7M21_RS18790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M21_RS18800	COG2814	Major facilitator Superfamily
C7M21_RS18810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M21_RS18815	COG1609	Transcriptional regulator
C7M21_RS18820	COG0693	protein deglycase activity
C7M21_RS18825	COG0737	Belongs to the 5'-nucleotidase family
C7M21_RS18840	COG0778	Nitroreductase
C7M21_RS18845	COG2188	Transcriptional regulator
C7M21_RS18850	COG0366	Alpha amylase catalytic
C7M21_RS18855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS18855	COG1263	PTS System
C7M21_RS18870	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M21_RS18880	COG1368	sulfuric ester hydrolase activity
C7M21_RS18890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M21_RS18890	COG1263	PTS System
C7M21_RS18895	COG0024	Methionine aminopeptidase
C7M21_RS18915	COG2258	MOSC domain
C7M21_RS18925	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M21_RS18930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M21_RS18935	COG2851	Citrate transporter
C7M21_RS18940	COG3181	Tripartite tricarboxylate transporter family receptor
C7M21_RS18945	COG4565	transcriptional regulatory protein
C7M21_RS18950	COG3290	protein histidine kinase activity
C7M21_RS18955	COG3764	Sortase (surface protein transpeptidase)
C7M21_RS18965	COG3279	Response regulator of the LytR AlgR family
C7M21_RS18970	COG2972	Histidine kinase
C7M21_RS18970	COG0745	RESPONSE REGULATOR receiver
C7M21_RS18990	COG0471	metal ion transport
C7M21_RS18995	COG3866	Pectate lyase
C7M21_RS19010	COG2130	NADP-dependent
C7M21_RS19015	COG0456	acetyltransferase
C7M21_RS19020	COG0513	Belongs to the DEAD box helicase family
C7M21_RS19025	COG0488	(ABC) transporter
C7M21_RS19030	COG2814	Major facilitator Superfamily
C7M21_RS19035	COG0789	Transcriptional regulator
C7M21_RS19040	COG0488	(ABC) transporter
C7M21_RS19045	COG0457	Tetratricopeptide repeat
C7M21_RS19045	COG0463	Glycosyl transferase, family 2
C7M21_RS19050	COG1028	Short-chain dehydrogenase reductase Sdr
C7M21_RS19055	COG0840	transmembrane signaling receptor activity
C7M21_RS19060	COG1012	belongs to the aldehyde dehydrogenase family
C7M21_RS19065	COG0531	amino acid
C7M21_RS19070	COG2223	nitrite transmembrane transporter activity
C7M21_RS19075	COG1442	glycosyl transferase family 8
C7M21_RS19080	COG1216	Glycosyl transferase, family 2
C7M21_RS19085	COG1442	glycosyl transferase family 8
C7M21_RS19090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M21_RS19095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M21_RS19100	COG1368	sulfuric ester hydrolase activity
C7M21_RS19105	COG4106	trans-aconitate 2-methyltransferase activity
C7M21_RS19150	COG1131	(ABC) transporter
C7M21_RS19165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M21_RS19165	COG2124	cytochrome p450
C7M21_RS19175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M21_RS19180	COG1846	Transcriptional regulator
C7M21_RS19185	COG0670	Belongs to the BI1 family
C7M21_RS19190	COG0196	riboflavin kinase activity
C7M21_RS19195	COG5583	Uncharacterized small protein (DUF2292)
C7M21_RS19200	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M21_RS19205	COG0346	lactoylglutathione lyase activity
C7M21_RS19210	COG2329	Antibiotic biosynthesis monooxygenase
C7M21_RS19215	COG2323	membrane
C7M21_RS19225	COG0454	-acetyltransferase
C7M21_RS19230	COG3546	catalase activity
C7M21_RS19255	COG5444	nuclease activity
C7M21_RS19265	COG5444	nuclease activity
C7M21_RS19295	COG1131	(ABC) transporter
C7M21_RS19305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M21_RS19310	COG1597	lipid kinase activity
C7M21_RS19315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M21_RS19320	COG1309	transcriptional regulator
C7M21_RS19340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M21_RS19345	COG1285	pathogenesis
C7M21_RS19350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M21_RS19355	COG4851	CamS sex pheromone cAM373 precursor
C7M21_RS19365	COG0210	DNA helicase
C7M21_RS19375	COG0069	glutamate synthase activity
C7M21_RS19380	COG4496	protein, YerC YecD
C7M21_RS19385	COG1470	cell adhesion involved in biofilm formation
C7M21_RS19390	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M21_RS19400	COG0151	Belongs to the GarS family
C7M21_RS19405	COG0138	bifunctional purine biosynthesis protein purh
C7M21_RS19410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M21_RS19420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine