locus-tag	class	description
C7M25_RS00010	COG1664	Polymer-forming cytoskeletal
C7M25_RS00015	COG1664	Polymer-forming cytoskeletal
C7M25_RS00020	COG0789	Transcriptional regulator
C7M25_RS00025	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M25_RS00035	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M25_RS00040	COG3382	B3 4 domain protein
C7M25_RS00050	COG1476	TRANSCRIPTIONal
C7M25_RS00070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M25_RS00075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M25_RS00080	COG1116	anion transmembrane transporter activity
C7M25_RS00090	COG0753	catalase activity
C7M25_RS00095	COG4608	Belongs to the ABC transporter superfamily
C7M25_RS00100	COG0444	Belongs to the ABC transporter superfamily
C7M25_RS00105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M25_RS00110	COG0601	transmembrane transport
C7M25_RS00115	COG0747	negative chemotaxis
C7M25_RS00125	COG0277	FAD linked oxidase domain protein
C7M25_RS00135	COG3340	Belongs to the peptidase S51 family
C7M25_RS00140	COG1757	Na H antiporter
C7M25_RS00250	COG0735	belongs to the Fur family
C7M25_RS00255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M25_RS00265	COG4129	membrane
C7M25_RS00270	COG1132	(ABC) transporter
C7M25_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS00300	COG1194	a g-specific adenine glycosylase
C7M25_RS00305	COG1988	membrane-bound metal-dependent
C7M25_RS00310	COG4485	Bacterial membrane protein, YfhO
C7M25_RS00315	COG0463	Glycosyl transferase, family 2
C7M25_RS00320	COG0596	Alpha beta hydrolase
C7M25_RS00325	COG5658	integral membrane protein
C7M25_RS00330	COG3103	Sh3 type 3 domain protein
C7M25_RS00345	COG3591	Belongs to the peptidase S1B family
C7M25_RS00355	COG2814	Major facilitator Superfamily
C7M25_RS00370	COG1090	epimerase
C7M25_RS00385	COG0778	Nitroreductase
C7M25_RS00390	COG0384	phenazine biosynthesis protein PhzF
C7M25_RS00395	COG0392	lysyltransferase activity
C7M25_RS00395	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M25_RS00400	COG1846	Transcriptional regulator
C7M25_RS00405	COG2814	Major facilitator Superfamily
C7M25_RS00410	COG2318	DinB family
C7M25_RS00415	COG2732	(Barnase) inhibitor
C7M25_RS00420	COG3848	Pyruvate phosphate dikinase
C7M25_RS00420	COG0574	Belongs to the PEP-utilizing enzyme family
C7M25_RS00425	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M25_RS00430	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M25_RS00435	COG1695	Transcriptional regulator
C7M25_RS00445	COG2514	catechol 2,3-dioxygenase activity
C7M25_RS00450	COG2259	Doxx family
C7M25_RS00455	COG1132	(ABC) transporter
C7M25_RS00460	COG1132	(ABC) transporter
C7M25_RS00465	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M25_RS00470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS00470	COG1263	PTS System
C7M25_RS00475	COG1737	Transcriptional regulator
C7M25_RS00480	COG1486	melibiose metabolic process
C7M25_RS00490	COG3284	Transcriptional regulator
C7M25_RS00495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M25_RS00500	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M25_RS00505	COG0022	dehydrogenase e1 component
C7M25_RS00510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M25_RS00515	COG4637	Psort location Cytoplasmic, score
C7M25_RS00520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M25_RS00530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M25_RS00535	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M25_RS00540	COG0598	Magnesium transport protein CorA
C7M25_RS00550	COG2084	Dehydrogenase
C7M25_RS00555	COG0726	polysaccharide deacetylase
C7M25_RS00565	COG0535	radical SAM domain protein
C7M25_RS00570	COG0668	transmembrane transport
C7M25_RS00580	COG0387	Pfam Sodium calcium exchanger
C7M25_RS00590	COG1295	ribonuclease BN
C7M25_RS00595	COG4980	gas vesicle protein
C7M25_RS00600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M25_RS00610	COG2814	Major facilitator Superfamily
C7M25_RS00620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M25_RS00625	COG1609	Transcriptional regulator
C7M25_RS00630	COG0693	protein deglycase activity
C7M25_RS00635	COG0737	Belongs to the 5'-nucleotidase family
C7M25_RS00650	COG0778	Nitroreductase
C7M25_RS00655	COG2188	Transcriptional regulator
C7M25_RS00660	COG0366	Alpha amylase catalytic
C7M25_RS00665	COG1263	PTS System
C7M25_RS00665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS00680	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M25_RS00690	COG1368	sulfuric ester hydrolase activity
C7M25_RS00700	COG1263	PTS System
C7M25_RS00700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS00705	COG0024	Methionine aminopeptidase
C7M25_RS00725	COG2258	MOSC domain
C7M25_RS00735	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M25_RS00740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS00745	COG2851	Citrate transporter
C7M25_RS00750	COG3181	Tripartite tricarboxylate transporter family receptor
C7M25_RS00755	COG4565	transcriptional regulatory protein
C7M25_RS00760	COG3290	protein histidine kinase activity
C7M25_RS00765	COG3764	Sortase (surface protein transpeptidase)
C7M25_RS00775	COG3279	Response regulator of the LytR AlgR family
C7M25_RS00780	COG2972	Histidine kinase
C7M25_RS00780	COG0745	RESPONSE REGULATOR receiver
C7M25_RS00800	COG0471	metal ion transport
C7M25_RS00805	COG3866	Pectate lyase
C7M25_RS00820	COG2130	NADP-dependent
C7M25_RS00825	COG0456	acetyltransferase
C7M25_RS00830	COG0513	Belongs to the DEAD box helicase family
C7M25_RS00835	COG0488	(ABC) transporter
C7M25_RS00840	COG2814	Major facilitator Superfamily
C7M25_RS00845	COG0789	Transcriptional regulator
C7M25_RS00850	COG0488	(ABC) transporter
C7M25_RS00855	COG0457	Tetratricopeptide repeat
C7M25_RS00855	COG0463	Glycosyl transferase, family 2
C7M25_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS00865	COG0840	transmembrane signaling receptor activity
C7M25_RS00870	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS00875	COG0531	amino acid
C7M25_RS00880	COG2223	nitrite transmembrane transporter activity
C7M25_RS00885	COG1442	glycosyl transferase family 8
C7M25_RS00890	COG1216	Glycosyl transferase, family 2
C7M25_RS00895	COG1442	glycosyl transferase family 8
C7M25_RS00900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS00905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M25_RS00910	COG1368	sulfuric ester hydrolase activity
C7M25_RS00915	COG4106	trans-aconitate 2-methyltransferase activity
C7M25_RS00960	COG1131	(ABC) transporter
C7M25_RS00975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M25_RS00975	COG2124	cytochrome p450
C7M25_RS00985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M25_RS00990	COG1846	Transcriptional regulator
C7M25_RS00995	COG0670	Belongs to the BI1 family
C7M25_RS01000	COG0196	riboflavin kinase activity
C7M25_RS01005	COG5583	Uncharacterized small protein (DUF2292)
C7M25_RS01010	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS01015	COG0346	lactoylglutathione lyase activity
C7M25_RS01020	COG2329	Antibiotic biosynthesis monooxygenase
C7M25_RS01025	COG2323	membrane
C7M25_RS01035	COG0454	-acetyltransferase
C7M25_RS01040	COG3546	catalase activity
C7M25_RS01065	COG5444	nuclease activity
C7M25_RS01075	COG5444	nuclease activity
C7M25_RS01105	COG1131	(ABC) transporter
C7M25_RS01115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M25_RS01120	COG1597	lipid kinase activity
C7M25_RS01125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M25_RS01130	COG1309	transcriptional regulator
C7M25_RS01150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M25_RS01155	COG1285	pathogenesis
C7M25_RS01160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M25_RS01165	COG4851	CamS sex pheromone cAM373 precursor
C7M25_RS01175	COG0210	DNA helicase
C7M25_RS01185	COG0069	glutamate synthase activity
C7M25_RS01190	COG4496	protein, YerC YecD
C7M25_RS01195	COG1470	cell adhesion involved in biofilm formation
C7M25_RS01200	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M25_RS01210	COG0151	Belongs to the GarS family
C7M25_RS01215	COG0138	bifunctional purine biosynthesis protein purh
C7M25_RS01220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M25_RS01230	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M25_RS01245	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M25_RS01250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M25_RS01255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M25_RS01260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M25_RS01265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M25_RS01285	COG3064	Membrane
C7M25_RS01290	COG2252	PERMEase
C7M25_RS01310	COG1305	Transglutaminase-like
C7M25_RS01315	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M25_RS01320	COG0714	Associated with various cellular activities
C7M25_RS01325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M25_RS01330	COG1113	amino acid transport
C7M25_RS01335	COG2132	Multicopper oxidase
C7M25_RS01345	COG0823	Involved in the tonB-independent uptake of proteins
C7M25_RS01350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M25_RS01355	COG1063	alcohol dehydrogenase
C7M25_RS01360	COG1595	DNA-templated transcription, initiation
C7M25_RS01370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M25_RS01370	COG2755	lipolytic protein G-D-S-L family
C7M25_RS01375	COG4260	virion core protein, lumpy skin disease virus
C7M25_RS01380	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M25_RS01385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M25_RS01390	COG1842	Phage shock protein A
C7M25_RS01400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M25_RS01405	COG2211	Major facilitator Superfamily
C7M25_RS01410	COG1063	alcohol dehydrogenase
C7M25_RS01415	COG0457	Tetratricopeptide repeat
C7M25_RS01435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M25_RS01440	COG1266	CAAX protease self-immunity
C7M25_RS01450	COG0805	protein transport
C7M25_RS01455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M25_RS01470	COG0488	(ABC) transporter
C7M25_RS01475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M25_RS01480	COG0456	acetyltransferase
C7M25_RS01485	COG1214	PFAM Peptidase M22, glycoprotease
C7M25_RS01490	COG0802	atpase or kinase
C7M25_RS01495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M25_RS01535	COG2814	Major facilitator Superfamily
C7M25_RS01540	COG0604	alcohol dehydrogenase
C7M25_RS01545	COG3832	glyoxalase III activity
C7M25_RS01555	COG0531	amino acid
C7M25_RS01560	COG1309	transcriptional regulator
C7M25_RS01565	COG2076	Multidrug Resistance protein
C7M25_RS01570	COG2076	Multidrug Resistance protein
C7M25_RS01575	COG2807	transmembrane transport
C7M25_RS01580	COG2186	Transcriptional regulator
C7M25_RS01585	COG2188	Transcriptional regulator
C7M25_RS01590	COG2814	Major facilitator Superfamily
C7M25_RS01595	COG1388	LysM domain
C7M25_RS01600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M25_RS01615	COG1819	glycosyl
C7M25_RS01620	COG1802	Transcriptional regulator
C7M25_RS01625	COG0473	3-isopropylmalate dehydrogenase activity
C7M25_RS01630	COG2226	methyltransferase
C7M25_RS01635	COG1051	belongs to the nudix hydrolase family
C7M25_RS01640	COG0697	spore germination
C7M25_RS01645	COG0789	Transcriptional regulator
C7M25_RS01645	COG4978	Transcriptional regulator
C7M25_RS01650	COG0456	acetyltransferase
C7M25_RS01655	COG0730	response to heat
C7M25_RS01665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M25_RS01670	COG2814	Major facilitator Superfamily
C7M25_RS01685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M25_RS01695	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7M25_RS01700	COG2409	Drug exporters of the RND superfamily
C7M25_RS01705	COG2197	response regulator
C7M25_RS01710	COG4585	Histidine kinase
C7M25_RS01715	COG0110	maltose O-acetyltransferase activity
C7M25_RS01725	COG0738	Major facilitator superfamily
C7M25_RS01735	COG5577	PFAM Coat F domain
C7M25_RS01740	COG1063	alcohol dehydrogenase
C7M25_RS01750	COG5577	PFAM Coat F domain
C7M25_RS01755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS01760	COG0697	spore germination
C7M25_RS01765	COG1309	transcriptional regulator
C7M25_RS01770	COG2814	Major facilitator Superfamily
C7M25_RS01805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS01815	COG0789	Transcriptional regulator
C7M25_RS01820	COG1064	alcohol dehydrogenase
C7M25_RS01845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M25_RS01850	COG2318	DinB family
C7M25_RS01855	COG0662	Cupin 2, conserved barrel domain protein
C7M25_RS01880	COG0277	FAD linked oxidase domain protein
C7M25_RS01895	COG0662	Cupin 2, conserved barrel domain protein
C7M25_RS01905	COG3621	Patatin-like phospholipase
C7M25_RS01920	COG1794	racemase activity, acting on amino acids and derivatives
C7M25_RS01925	COG1329	Transcriptional regulator
C7M25_RS01930	COG1278	Cold shock
C7M25_RS01950	COG0604	alcohol dehydrogenase
C7M25_RS01960	COG2910	NAD(P)H-binding
C7M25_RS01965	COG1959	2 iron, 2 sulfur cluster binding
C7M25_RS01980	COG2030	dehydratase
C7M25_RS01990	COG1846	Transcriptional regulator
C7M25_RS01995	COG0477	Major facilitator Superfamily
C7M25_RS02000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M25_RS02025	COG0457	Tetratricopeptide repeat
C7M25_RS02030	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M25_RS02035	COG0457	Tetratricopeptide repeat
C7M25_RS02050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M25_RS02055	COG1090	epimerase
C7M25_RS02060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M25_RS02065	COG1959	2 iron, 2 sulfur cluster binding
C7M25_RS02130	COG2183	response to ionizing radiation
C7M25_RS02135	COG2208	phosphoserine phosphatase activity
C7M25_RS02140	COG1191	sigma factor activity
C7M25_RS02150	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS02155	COG2208	phosphoserine phosphatase activity
C7M25_RS02160	COG2172	sigma factor antagonist activity
C7M25_RS02165	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS02170	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS02175	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M25_RS02180	COG0864	Transcriptional regulator
C7M25_RS02185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M25_RS02190	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M25_RS02200	COG0705	Rhomboid family
C7M25_RS02205	COG3428	Bacterial PH domain
C7M25_RS02210	COG3402	PFAM membrane-flanked domain
C7M25_RS02215	COG0513	Belongs to the DEAD box helicase family
C7M25_RS02220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M25_RS02230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS02235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M25_RS02250	COG1960	acyl-CoA dehydrogenase activity
C7M25_RS02260	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M25_RS02265	COG1131	(ABC) transporter
C7M25_RS02270	COG0628	permease
C7M25_RS02275	COG1301	dicarboxylic acid transport
C7M25_RS02280	COG4565	transcriptional regulatory protein
C7M25_RS02285	COG3290	protein histidine kinase activity
C7M25_RS02290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M25_RS02295	COG3546	catalase activity
C7M25_RS02300	COG2329	Antibiotic biosynthesis monooxygenase
C7M25_RS02305	COG0662	Cupin 2, conserved barrel domain protein
C7M25_RS02310	COG3729	General stress protein
C7M25_RS02315	COG2217	Heavy metal translocating P-type atpase
C7M25_RS02320	COG2076	Multidrug Resistance protein
C7M25_RS02330	COG4876	unkown
C7M25_RS02340	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M25_RS02365	COG0028	Belongs to the TPP enzyme family
C7M25_RS02370	COG0494	nUDIX hydrolase
C7M25_RS02375	COG0531	amino acid
C7M25_RS02385	COG1215	transferase activity, transferring glycosyl groups
C7M25_RS02390	COG5298	Protein conserved in bacteria
C7M25_RS02395	COG3706	GGDEF domain
C7M25_RS02405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M25_RS02405	COG0551	DNA topoisomerase type I activity
C7M25_RS02410	COG1522	sequence-specific DNA binding
C7M25_RS02415	COG2814	Major facilitator Superfamily
C7M25_RS02425	COG3871	stress protein (general stress protein 26)
C7M25_RS02430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M25_RS02435	COG1917	Cupin 2, conserved barrel domain protein
C7M25_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS02445	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS02450	COG3711	transcriptional antiterminator
C7M25_RS02455	COG4989	oxidoreductase activity
C7M25_RS02460	COG0768	penicillin binding
C7M25_RS02465	COG2329	Antibiotic biosynthesis monooxygenase
C7M25_RS02475	COG2755	lipolytic protein G-D-S-L family
C7M25_RS02480	COG1414	Transcriptional regulator
C7M25_RS02485	COG1984	allophanate hydrolase subunit 2
C7M25_RS02490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M25_RS02500	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M25_RS02510	COG0561	phosphatase activity
C7M25_RS02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M25_RS02530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS02535	COG2213	PTS system mannitol-specific
C7M25_RS02545	COG1349	DNA-binding transcription factor activity
C7M25_RS02550	COG2372	response to copper ion
C7M25_RS02550	COG1276	copper resistance
C7M25_RS02555	COG4549	nuclear export factor GLE1
C7M25_RS02560	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS02565	COG4975	Glucose uptake
C7M25_RS02570	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS02575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS02585	COG0640	Transcriptional regulator
C7M25_RS02590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M25_RS02595	COG0778	Nitroreductase
C7M25_RS02600	COG1309	transcriptional regulator
C7M25_RS02605	COG2814	Major facilitator Superfamily
C7M25_RS02610	COG4607	ABC-type enterochelin transport system periplasmic component
C7M25_RS02615	COG4604	ABC transporter, ATP-binding protein
C7M25_RS02620	COG4605	iron ion homeostasis
C7M25_RS02625	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS02630	COG0527	aspartate kinase activity
C7M25_RS02645	COG0457	Tetratricopeptide repeat
C7M25_RS02650	COG3850	Histidine kinase
C7M25_RS02650	COG5002	protein histidine kinase activity
C7M25_RS02655	COG0745	RESPONSE REGULATOR receiver
C7M25_RS02660	COG0577	efflux transmembrane transporter activity
C7M25_RS02665	COG1136	(ABC) transporter
C7M25_RS02670	COG2079	MmgE PrpD family protein
C7M25_RS02680	COG1126	abc transporter atp-binding protein
C7M25_RS02685	COG0765	amino acid transport
C7M25_RS02690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS02705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M25_RS02715	COG0697	spore germination
C7M25_RS02725	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M25_RS02730	COG3104	oligopeptide transport
C7M25_RS02745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M25_RS02750	COG0163	prenyltransferase activity
C7M25_RS02755	COG0583	DNA-binding transcription factor activity
C7M25_RS02760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS02765	COG0765	amino acid transport
C7M25_RS02770	COG1126	abc transporter atp-binding protein
C7M25_RS02775	COG2364	Membrane
C7M25_RS02785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS02790	COG0697	spore germination
C7M25_RS02805	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M25_RS02810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS02815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS02820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS02825	COG1733	regulation of RNA biosynthetic process
C7M25_RS02830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M25_RS02835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M25_RS02840	COG3209	COG3209 Rhs family protein
C7M25_RS02850	COG2723	6-phospho-beta-galactosidase activity
C7M25_RS02860	COG1714	RDD family
C7M25_RS02865	COG1063	alcohol dehydrogenase
C7M25_RS02870	COG0523	cobalamin synthesis protein
C7M25_RS02875	COG2223	nitrite transmembrane transporter activity
C7M25_RS02880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M25_RS02885	COG0243	molybdopterin cofactor binding
C7M25_RS02890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M25_RS02895	COG2146	nitrite reductase [NAD(P)H] activity
C7M25_RS02900	COG1587	Uroporphyrinogen-III synthase
C7M25_RS02900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M25_RS02910	COG2508	Transcriptional regulator
C7M25_RS02915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M25_RS02920	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS02925	COG0506	proline dehydrogenase activity
C7M25_RS02930	COG3541	Predicted nucleotidyltransferase
C7M25_RS02935	COG3458	cephalosporin-C deacetylase activity
C7M25_RS02940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M25_RS02945	COG2271	Major facilitator Superfamily
C7M25_RS02950	COG1082	Xylose isomerase domain protein TIM barrel
C7M25_RS02955	COG1660	Displays ATPase and GTPase activities
C7M25_RS02970	COG3665	Urea carboxylase-associated protein
C7M25_RS02975	COG1113	amino acid transport
C7M25_RS02980	COG3403	YqcI/YcgG family
C7M25_RS02985	COG1280	lysine exporter protein (LysE YggA)
C7M25_RS02990	COG1846	Transcriptional regulator
C7M25_RS02995	COG2814	Major facilitator Superfamily
C7M25_RS03005	COG0366	Alpha amylase catalytic
C7M25_RS03015	COG1288	antiporter activity
C7M25_RS03020	COG1473	amidohydrolase
C7M25_RS03025	COG2113	Glycine betaine
C7M25_RS03030	COG4176	ABC-type proline glycine betaine transport system permease component
C7M25_RS03035	COG4175	Glycine betaine
C7M25_RS03035	COG0517	IMP dehydrogenase activity
C7M25_RS03040	COG0477	Major facilitator Superfamily
C7M25_RS03045	COG3853	Toxic anion resistance protein (TelA)
C7M25_RS03055	COG0861	Integral membrane protein TerC family
C7M25_RS03060	COG2310	stress, protein
C7M25_RS03065	COG2310	stress, protein
C7M25_RS03070	COG2310	stress, protein
C7M25_RS03075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M25_RS03080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M25_RS03085	COG1121	(ABC) transporter
C7M25_RS03090	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M25_RS03095	COG0366	Alpha amylase catalytic
C7M25_RS03100	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS03105	COG0457	Tetratricopeptide repeat
C7M25_RS03110	COG1876	peptidase activity
C7M25_RS03115	COG1595	DNA-templated transcription, initiation
C7M25_RS03120	COG1595	DNA-templated transcription, initiation
C7M25_RS03130	COG0667	Aldo Keto reductase
C7M25_RS03135	COG1405	negative regulation of cell septum assembly
C7M25_RS03135	COG3012	SEC-C Motif Domain Protein
C7M25_RS03140	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M25_RS03145	COG0252	asparaginase activity
C7M25_RS03150	COG1309	transcriptional regulator
C7M25_RS03155	COG0477	Major facilitator Superfamily
C7M25_RS03160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M25_RS03170	COG0805	protein transport
C7M25_RS03175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M25_RS03180	COG3540	Alkaline phosphatase
C7M25_RS03185	COG3773	Cell wall hydrolase
C7M25_RS03195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS03200	COG2259	Doxx family
C7M25_RS03205	COG0346	lactoylglutathione lyase activity
C7M25_RS03210	COG0778	Nitroreductase
C7M25_RS03215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M25_RS03230	COG0784	Response regulator, receiver
C7M25_RS03235	COG4191	Histidine kinase
C7M25_RS03240	COG2066	Belongs to the glutaminase family
C7M25_RS03245	COG1115	amino acid carrier protein
C7M25_RS03250	COG2040	homocysteine
C7M25_RS03255	COG0833	amino acid
C7M25_RS03260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS03265	COG1301	dicarboxylic acid transport
C7M25_RS03280	COG0688	phosphatidylethanolamine metabolic process
C7M25_RS03285	COG0586	Pfam SNARE associated Golgi protein
C7M25_RS03290	COG1183	phosphatidylcholine synthase activity
C7M25_RS03300	COG0371	Dehydrogenase
C7M25_RS03315	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS03325	COG2368	4-hydroxyphenylacetate
C7M25_RS03335	COG2271	Major facilitator Superfamily
C7M25_RS03340	COG0584	glycerophosphoryl diester phosphodiesterase
C7M25_RS03355	COG0531	amino acid
C7M25_RS03385	COG1011	Hydrolase
C7M25_RS03390	COG1113	amino acid transport
C7M25_RS03395	COG1846	Transcriptional regulator
C7M25_RS03400	COG1380	Effector of murein hydrolase LrgA
C7M25_RS03405	COG1346	cytolysis
C7M25_RS03455	COG4856	YbbR-like protein
C7M25_RS03460	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M25_RS03465	COG5662	AntiSigma factor
C7M25_RS03470	COG1595	DNA-templated transcription, initiation
C7M25_RS03500	COG1683	Conserved Protein
C7M25_RS03505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M25_RS03515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS03515	COG1263	PTS System
C7M25_RS03520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M25_RS03525	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M25_RS03530	COG3876	Protein conserved in bacteria
C7M25_RS03535	COG2207	Transcriptional regulator
C7M25_RS03535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M25_RS03540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M25_RS03545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS03550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS03555	COG2819	hydrolase of the alpha beta superfamily
C7M25_RS03560	COG0385	Bile acid
C7M25_RS03565	COG0659	secondary active sulfate transmembrane transporter activity
C7M25_RS03580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS03585	COG0738	Major facilitator superfamily
C7M25_RS03645	COG0726	polysaccharide deacetylase
C7M25_RS03650	COG2194	sulfuric ester hydrolase activity
C7M25_RS03660	COG0489	protein tyrosine kinase activity
C7M25_RS03665	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS03675	COG2318	DinB family
C7M25_RS03680	COG2226	methyltransferase
C7M25_RS03700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M25_RS03705	COG1122	ATPase activity
C7M25_RS03710	COG1122	ATPase activity
C7M25_RS03735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M25_RS03740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M25_RS03750	COG0024	Methionine aminopeptidase
C7M25_RS03760	COG0201	protein transport
C7M25_RS03770	COG1841	ribosomal large subunit assembly
C7M25_RS03820	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M25_RS03825	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M25_RS03835	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M25_RS03840	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M25_RS03850	COG0089	rRNA binding
C7M25_RS03865	COG0051	transcription antitermination factor activity, RNA binding
C7M25_RS03870	COG0596	Alpha beta hydrolase
C7M25_RS03895	COG1358	cellular component organization or biogenesis
C7M25_RS03910	COG2813	Specifically methylates the guanine in position
C7M25_RS03915	COG0222	ribosome binding
C7M25_RS03930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M25_RS03935	COG0250	Participates in transcription elongation, termination and antitermination
C7M25_RS03940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M25_RS03945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M25_RS03950	COG1595	DNA-templated transcription, initiation
C7M25_RS03955	COG3688	RNA-binding protein containing a PIN domain
C7M25_RS03960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M25_RS03965	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M25_RS03975	COG1045	serine acetyltransferase
C7M25_RS03995	COG4956	integral membrane protein (PIN domain superfamily)
C7M25_RS04000	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M25_RS04005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M25_RS04010	COG0542	response to heat
C7M25_RS04020	COG3880	PFAM UvrB UvrC protein
C7M25_RS04025	COG4463	regulation of RNA biosynthetic process
C7M25_RS04105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M25_RS04110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M25_RS04115	COG1396	sequence-specific DNA binding
C7M25_RS04120	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M25_RS04125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M25_RS04130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M25_RS04135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS04140	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M25_RS04145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M25_RS04150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M25_RS04155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M25_RS04170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M25_RS04180	COG0037	tRNA processing
C7M25_RS04185	COG0515	serine threonine protein kinase
C7M25_RS04190	COG2304	oxidoreductase activity
C7M25_RS04195	COG2208	phosphoserine phosphatase activity
C7M25_RS04210	COG1098	S1 RNA binding domain
C7M25_RS04215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M25_RS04230	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M25_RS04235	COG3956	TIGRFAM MazG family protein
C7M25_RS04240	COG2244	polysaccharide biosynthetic process
C7M25_RS04245	COG2002	toxin-antitoxin pair type II binding
C7M25_RS04250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M25_RS04270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M25_RS04285	COG0251	oxidation-reduction process
C7M25_RS04290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M25_RS04305	COG4466	Protein conserved in bacteria
C7M25_RS04315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M25_RS04320	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M25_RS04325	COG3584	3D domain protein
C7M25_RS04325	COG3583	domain protein
C7M25_RS04330	COG0084	hydrolase, TatD family'
C7M25_RS04335	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M25_RS04335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M25_RS04340	COG2002	toxin-antitoxin pair type II binding
C7M25_RS04345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M25_RS04355	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M25_RS04365	COG1774	PSP1 C-terminal conserved region
C7M25_RS04370	COG0470	DNA polymerase III
C7M25_RS04375	COG1728	Protein conserved in bacteria
C7M25_RS04380	COG3870	Protein conserved in bacteria
C7M25_RS04390	COG1982	Orn Lys Arg decarboxylase major
C7M25_RS04395	COG3853	Toxic anion resistance protein (TelA)
C7M25_RS04400	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M25_RS04450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M25_RS04455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M25_RS04465	COG0590	tRNA wobble adenosine to inosine editing
C7M25_RS04470	COG1335	isochorismatase
C7M25_RS04475	COG1388	LysM domain
C7M25_RS04475	COG3858	chitin binding
C7M25_RS04480	COG1428	Deoxynucleoside kinase
C7M25_RS04485	COG1428	Deoxynucleoside kinase
C7M25_RS04495	COG1929	Belongs to the glycerate kinase type-1 family
C7M25_RS04515	COG1686	Belongs to the peptidase S11 family
C7M25_RS04520	COG0516	GMP reductase activity
C7M25_RS04520	COG0517	IMP dehydrogenase activity
C7M25_RS04555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M25_RS04560	COG0187	DNA topoisomerase II activity
C7M25_RS04575	COG2501	S4 domain
C7M25_RS04580	COG0592	DNA-directed DNA polymerase activity
C7M25_RS04590	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M25_RS04600	COG0706	membrane insertase activity
C7M25_RS04605	COG1847	R3H domain protein
C7M25_RS04630	COG1192	Involved in chromosome partitioning
C7M25_RS04635	COG1475	DNA binding
C7M25_RS04650	COG3949	Membrane
C7M25_RS04655	COG4481	Protein conserved in bacteria
C7M25_RS04660	COG0243	molybdopterin cofactor binding
C7M25_RS04665	COG0012	GTP binding
C7M25_RS04675	COG0629	single-stranded DNA binding
C7M25_RS04685	COG2169	Transcriptional regulator
C7M25_RS04690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M25_RS04695	COG0708	Exodeoxyribonuclease III
C7M25_RS04700	COG1609	Transcriptional regulator
C7M25_RS04705	COG0346	lactoylglutathione lyase activity
C7M25_RS04710	COG2814	Major facilitator Superfamily
C7M25_RS04710	COG0477	Major facilitator Superfamily
C7M25_RS04715	COG1266	CAAX protease self-immunity
C7M25_RS04720	COG1331	Highly conserved protein containing a thioredoxin domain
C7M25_RS04725	COG0697	spore germination
C7M25_RS04730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS04750	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS04755	COG0583	DNA-binding transcription factor activity
C7M25_RS04760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M25_RS04770	COG2153	protein acetylation
C7M25_RS04775	COG1846	Transcriptional regulator
C7M25_RS04780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS04785	COG1846	Transcriptional regulator
C7M25_RS04790	COG0778	Nitroreductase
C7M25_RS04800	COG0583	DNA-binding transcription factor activity
C7M25_RS04805	COG2814	Major facilitator Superfamily
C7M25_RS04815	COG0583	DNA-binding transcription factor activity
C7M25_RS04820	COG2211	Major facilitator Superfamily
C7M25_RS04825	COG2318	DinB family
C7M25_RS04830	COG1802	Transcriptional regulator
C7M25_RS04835	COG1621	beta-fructofuranosidase activity
C7M25_RS04840	COG1621	beta-fructofuranosidase activity
C7M25_RS04845	COG0697	spore germination
C7M25_RS04855	COG1733	regulation of RNA biosynthetic process
C7M25_RS04860	COG5577	PFAM Coat F domain
C7M25_RS04870	COG4241	membrane
C7M25_RS04875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M25_RS04895	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS04900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M25_RS04915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M25_RS04920	COG3093	addiction module antidote protein HigA
C7M25_RS04940	COG0305	Participates in initiation and elongation during chromosome replication
C7M25_RS04945	COG0346	lactoylglutathione lyase activity
C7M25_RS04975	COG0745	RESPONSE REGULATOR receiver
C7M25_RS04980	COG5002	protein histidine kinase activity
C7M25_RS04985	COG4863	YycH protein
C7M25_RS04990	COG4853	Protein conserved in bacteria
C7M25_RS04995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M25_RS05000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M25_RS05005	COG0745	RESPONSE REGULATOR receiver
C7M25_RS05010	COG3850	Histidine kinase
C7M25_RS05010	COG5002	protein histidine kinase activity
C7M25_RS05015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M25_RS05030	COG0488	(ABC) transporter
C7M25_RS05040	COG3829	transcription factor binding
C7M25_RS05045	COG0640	Transcriptional regulator
C7M25_RS05050	COG5658	integral membrane protein
C7M25_RS05055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M25_RS05060	COG0833	amino acid
C7M25_RS05065	COG0010	Belongs to the arginase family
C7M25_RS05070	COG0457	Tetratricopeptide repeat
C7M25_RS05075	COG0456	acetyltransferase
C7M25_RS05080	COG0667	Aldo Keto reductase
C7M25_RS05085	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M25_RS05125	COG0210	DNA helicase
C7M25_RS05155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M25_RS05160	COG2068	MobA-Related Protein
C7M25_RS05175	COG2080	2 iron, 2 sulfur cluster binding
C7M25_RS05185	COG1113	amino acid transport
C7M25_RS05190	COG3177	Filamentation induced by cAMP protein fic
C7M25_RS05195	COG3634	alkyl hydroperoxide reductase activity
C7M25_RS05200	COG0450	alkyl hydroperoxide reductase
C7M25_RS05210	COG1714	RDD family
C7M25_RS05215	COG2814	Major facilitator Superfamily
C7M25_RS05220	COG0640	Transcriptional regulator
C7M25_RS05230	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M25_RS05235	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS05240	COG1309	transcriptional regulator
C7M25_RS05245	COG3239	Fatty acid desaturase
C7M25_RS05250	COG4585	Histidine kinase
C7M25_RS05255	COG2197	response regulator
C7M25_RS05260	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS05275	COG2814	Major facilitator Superfamily
C7M25_RS05280	COG0667	Aldo Keto reductase
C7M25_RS05285	COG1349	DNA-binding transcription factor activity
C7M25_RS05315	COG2814	Major facilitator Superfamily
C7M25_RS05325	COG1082	Xylose isomerase domain protein TIM barrel
C7M25_RS05340	COG0745	RESPONSE REGULATOR receiver
C7M25_RS05345	COG2205	protein histidine kinase activity
C7M25_RS05350	COG1136	(ABC) transporter
C7M25_RS05355	COG0577	efflux transmembrane transporter activity
C7M25_RS05360	COG5294	Protein conserved in bacteria
C7M25_RS05365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M25_RS05395	COG0561	phosphatase activity
C7M25_RS05400	COG2390	Transcriptional regulator
C7M25_RS05410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M25_RS05415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M25_RS05420	COG0833	amino acid
C7M25_RS05425	COG0010	Belongs to the arginase family
C7M25_RS05450	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M25_RS05455	COG0494	nUDIX hydrolase
C7M25_RS05465	COG2190	(PTS) system
C7M25_RS05465	COG1263	PTS System
C7M25_RS05465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS05470	COG2723	6-phospho-beta-galactosidase activity
C7M25_RS05475	COG0589	response to stress
C7M25_RS05480	COG0697	spore germination
C7M25_RS05490	COG3209	COG3209 Rhs family protein
C7M25_RS05545	COG0513	Belongs to the DEAD box helicase family
C7M25_RS05550	COG2270	Major facilitator Superfamily
C7M25_RS05555	COG3711	transcriptional antiterminator
C7M25_RS05560	COG2273	Hydrolase Family 16
C7M25_RS05565	COG2851	Citrate transporter
C7M25_RS05570	COG0693	protein deglycase activity
C7M25_RS05570	COG0753	catalase activity
C7M25_RS05585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M25_RS05590	COG0500	methyltransferase
C7M25_RS05595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M25_RS05600	COG4894	glucomannan catabolic process
C7M25_RS05610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M25_RS05620	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS05625	COG2508	Transcriptional regulator
C7M25_RS05630	COG3842	ATPase activity
C7M25_RS05635	COG0726	polysaccharide deacetylase
C7M25_RS05640	COG3493	citrate carrier protein
C7M25_RS05645	COG1271	oxidase subunit
C7M25_RS05650	COG1294	oxidase, subunit
C7M25_RS05655	COG4988	ABC transporter
C7M25_RS05660	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M25_RS05665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M25_RS05670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M25_RS05675	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M25_RS05680	COG0753	catalase activity
C7M25_RS05690	COG1482	cell wall glycoprotein biosynthetic process
C7M25_RS05695	COG1940	carbohydrate kinase activity
C7M25_RS05700	COG2723	6-phospho-beta-galactosidase activity
C7M25_RS05705	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS05710	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M25_RS05715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS05720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M25_RS05725	COG0640	Transcriptional regulator
C7M25_RS05735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS05740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS05750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS05750	COG3711	transcriptional antiterminator
C7M25_RS05755	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS05760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS05765	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M25_RS05770	COG1486	melibiose metabolic process
C7M25_RS05775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS05780	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M25_RS05790	COG1696	Membrane protein involved in D-alanine export
C7M25_RS05805	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M25_RS05810	COG2357	RelA SpoT domain protein
C7M25_RS05815	COG1442	glycosyl transferase family 8
C7M25_RS05820	COG1404	Belongs to the peptidase S8 family
C7M25_RS05825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS05830	COG0346	lactoylglutathione lyase activity
C7M25_RS05835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M25_RS05840	COG5504	Zn-dependent protease
C7M25_RS05845	COG0789	Transcriptional regulator
C7M25_RS05850	COG4895	conserved protein (DUF2196)
C7M25_RS05855	COG1346	cytolysis
C7M25_RS05865	COG0583	DNA-binding transcription factor activity
C7M25_RS05880	COG2822	iron ion transport
C7M25_RS05885	COG2837	iron assimilation
C7M25_RS05890	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M25_RS05910	COG1309	transcriptional regulator
C7M25_RS05915	COG2246	polysaccharide biosynthetic process
C7M25_RS05920	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M25_RS05925	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M25_RS05935	COG2261	transglycosylase associated protein
C7M25_RS05940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M25_RS05945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M25_RS05965	COG0454	-acetyltransferase
C7M25_RS05970	COG0772	Belongs to the SEDS family
C7M25_RS05975	COG0778	Nitroreductase
C7M25_RS05980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M25_RS05985	COG1404	Belongs to the peptidase S8 family
C7M25_RS05995	COG3711	transcriptional antiterminator
C7M25_RS06000	COG1263	PTS System
C7M25_RS06000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS06005	COG1621	beta-fructofuranosidase activity
C7M25_RS06015	COG0351	phosphomethylpyrimidine kinase
C7M25_RS06020	COG1695	Transcriptional regulator
C7M25_RS06035	COG1216	Glycosyl transferase, family 2
C7M25_RS06050	COG2233	PERMEase
C7M25_RS06055	COG2363	Small membrane protein
C7M25_RS06065	COG0463	Glycosyl transferase, family 2
C7M25_RS06070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M25_RS06075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M25_RS06080	COG0456	acetyltransferase
C7M25_RS06085	COG2089	acid synthase
C7M25_RS06090	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M25_RS06095	COG3980	spore coat polysaccharide biosynthesis protein
C7M25_RS06100	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M25_RS06105	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M25_RS06110	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M25_RS06115	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M25_RS06125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M25_RS06130	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS06135	COG4187	Peptidase family M20/M25/M40
C7M25_RS06140	COG0833	amino acid
C7M25_RS06145	COG2814	Major facilitator Superfamily
C7M25_RS06150	COG2814	Major facilitator Superfamily
C7M25_RS06180	COG0436	Aminotransferase
C7M25_RS06185	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS06195	COG0280	phosphate acetyltransferase
C7M25_RS06200	COG2855	membrane
C7M25_RS06205	COG0583	DNA-binding transcription factor activity
C7M25_RS06235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M25_RS06240	COG1131	(ABC) transporter
C7M25_RS06250	COG1695	Transcriptional regulator
C7M25_RS06265	COG1078	dGTPase activity
C7M25_RS06270	COG3465	dGTPase activity
C7M25_RS06275	COG0531	amino acid
C7M25_RS06280	COG1846	Transcriptional regulator
C7M25_RS06285	COG1942	4-Oxalocrotonate Tautomerase
C7M25_RS06290	COG1994	Peptidase M50
C7M25_RS06305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M25_RS06310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M25_RS06315	COG0010	Belongs to the arginase family
C7M25_RS06360	COG0457	Tetratricopeptide repeat
C7M25_RS06365	COG3391	amine dehydrogenase activity
C7M25_RS06370	COG3391	amine dehydrogenase activity
C7M25_RS06380	COG4506	Protein conserved in bacteria
C7M25_RS06390	COG2223	nitrite transmembrane transporter activity
C7M25_RS06395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M25_RS06405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M25_RS06410	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M25_RS06415	COG1140	nitrate reductase beta subunit
C7M25_RS06420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M25_RS06425	COG2181	nitrate reductase activity
C7M25_RS06435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M25_RS06440	COG1132	(ABC) transporter
C7M25_RS06455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M25_RS06460	COG0247	lactate metabolic process
C7M25_RS06460	COG2181	nitrate reductase activity
C7M25_RS06475	COG4821	SIS domain
C7M25_RS06480	COG2204	response regulator
C7M25_RS06485	COG0191	fructose-bisphosphate aldolase activity
C7M25_RS06495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M25_RS06500	COG1494	fructose-1,6-bisphosphatase
C7M25_RS06505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M25_RS06510	COG0254	rRNA binding
C7M25_RS06520	COG0281	malic enzyme
C7M25_RS06525	COG0679	Auxin Efflux Carrier
C7M25_RS06530	COG0789	Transcriptional regulator
C7M25_RS06535	COG0346	lactoylglutathione lyase activity
C7M25_RS06540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M25_RS06545	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M25_RS06565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M25_RS06570	COG0009	L-threonylcarbamoyladenylate synthase
C7M25_RS06580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M25_RS06585	COG0698	ribose 5-phosphate isomerase
C7M25_RS06615	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M25_RS06655	COG4836	Membrane
C7M25_RS06665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M25_RS06670	COG2385	sporulation resulting in formation of a cellular spore
C7M25_RS06675	COG2304	oxidoreductase activity
C7M25_RS06680	COG2304	oxidoreductase activity
C7M25_RS06685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M25_RS06695	COG0457	Tetratricopeptide repeat
C7M25_RS06700	COG1994	Peptidase M50
C7M25_RS06705	COG3237	CsbD-like
C7M25_RS06710	COG0831	urea catabolic process
C7M25_RS06725	COG1959	2 iron, 2 sulfur cluster binding
C7M25_RS06730	COG0726	polysaccharide deacetylase
C7M25_RS06740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M25_RS06755	COG1247	-acetyltransferase
C7M25_RS06760	COG0739	heme binding
C7M25_RS06770	COG0671	phosphoesterase, PA-phosphatase related
C7M25_RS06775	COG0772	Belongs to the SEDS family
C7M25_RS06780	COG0347	Belongs to the P(II) protein family
C7M25_RS06785	COG0004	ammonium transporteR
C7M25_RS06790	COG1335	isochorismatase
C7M25_RS06795	COG0477	Major facilitator Superfamily
C7M25_RS06800	COG1953	Uracil, thiamine, allantoin
C7M25_RS06805	COG2814	Major facilitator Superfamily
C7M25_RS06810	COG1846	Transcriptional regulator
C7M25_RS06815	COG1609	Transcriptional regulator
C7M25_RS06820	COG1077	Cell shape determining protein MreB Mrl
C7M25_RS06825	COG4786	Flagellar basal body rod
C7M25_RS06830	COG4786	Flagellar basal body rod
C7M25_RS06835	COG0457	Tetratricopeptide repeat
C7M25_RS06860	COG0629	single-stranded DNA binding
C7M25_RS06865	COG1349	DNA-binding transcription factor activity
C7M25_RS06870	COG0561	phosphatase activity
C7M25_RS06875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M25_RS06880	COG4715	Zinc finger, swim domain protein
C7M25_RS06890	COG3944	biosynthesis protein
C7M25_RS06895	COG0489	protein tyrosine kinase activity
C7M25_RS06900	COG4464	protein tyrosine phosphatase activity
C7M25_RS06905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M25_RS06910	COG3878	Protein conserved in bacteria
C7M25_RS06925	COG5444	nuclease activity
C7M25_RS06945	COG2059	Chromate
C7M25_RS06950	COG2059	Chromate
C7M25_RS06955	COG1522	sequence-specific DNA binding
C7M25_RS06960	COG0405	Gamma-glutamyltransferase
C7M25_RS06970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M25_RS06980	COG5337	Spore coat protein CotH
C7M25_RS06995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M25_RS07000	COG0583	DNA-binding transcription factor activity
C7M25_RS07005	COG0028	Belongs to the TPP enzyme family
C7M25_RS07010	COG3527	Alpha-acetolactate decarboxylase
C7M25_RS07015	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M25_RS07020	COG3103	Sh3 type 3 domain protein
C7M25_RS07025	COG1879	ABC-type sugar transport system periplasmic component
C7M25_RS07030	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M25_RS07035	COG1129	ABC transporter
C7M25_RS07045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M25_RS07050	COG1609	Transcriptional regulator
C7M25_RS07060	COG0814	amino acid
C7M25_RS07065	COG0697	spore germination
C7M25_RS07070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M25_RS07080	COG2843	Capsule synthesis protein
C7M25_RS07090	COG0791	NLP P60 protein
C7M25_RS07095	COG2433	Pfam Transposase IS66
C7M25_RS07100	COG0561	phosphatase activity
C7M25_RS07105	COG1316	TRANSCRIPTIONal
C7M25_RS07110	COG2814	Major facilitator Superfamily
C7M25_RS07115	COG1215	transferase activity, transferring glycosyl groups
C7M25_RS07125	COG0814	amino acid
C7M25_RS07130	COG0697	spore germination
C7M25_RS07135	COG1482	cell wall glycoprotein biosynthetic process
C7M25_RS07140	COG4193	domain, Protein
C7M25_RS07145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M25_RS07150	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M25_RS07155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M25_RS07165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M25_RS07170	COG1682	transport, permease protein
C7M25_RS07175	COG1134	teichoic acid transport
C7M25_RS07180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M25_RS07185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M25_RS07190	COG1316	TRANSCRIPTIONal
C7M25_RS07200	COG2385	sporulation resulting in formation of a cellular spore
C7M25_RS07200	COG2247	cell wall binding repeat
C7M25_RS07205	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS07205	COG2247	cell wall binding repeat
C7M25_RS07215	COG2244	polysaccharide biosynthetic process
C7M25_RS07220	COG0297	glycogen (starch) synthase activity
C7M25_RS07220	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS07225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M25_RS07230	COG3307	-O-antigen
C7M25_RS07235	COG3206	protein involved in exopolysaccharide biosynthesis
C7M25_RS07240	COG1215	transferase activity, transferring glycosyl groups
C7M25_RS07245	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS07250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M25_RS07255	COG1316	TRANSCRIPTIONal
C7M25_RS07260	COG1739	Uncharacterized protein family UPF0029
C7M25_RS07265	COG4585	Histidine kinase
C7M25_RS07270	COG2197	response regulator
C7M25_RS07275	COG1307	EDD domain protein, DegV family
C7M25_RS07280	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M25_RS07290	COG1040	competence protein
C7M25_RS07300	COG2747	anti-sigma28 factor FlgM
C7M25_RS07305	COG3418	PFAM FlgN family protein
C7M25_RS07310	COG4786	Flagellar basal body rod
C7M25_RS07310	COG1256	bacterial-type flagellum assembly
C7M25_RS07315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M25_RS07335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M25_RS07340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M25_RS07345	COG1516	flagellar protein fliS
C7M25_RS07360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M25_RS07375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS07380	COG2010	Cytochrome c
C7M25_RS07385	COG2884	Cell division ATP-binding protein ftsE
C7M25_RS07390	COG2177	Part of the ABC transporter FtsEX involved in
C7M25_RS07395	COG3420	alginic acid biosynthetic process
C7M25_RS07400	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS07400	COG0793	Belongs to the peptidase S41A family
C7M25_RS07410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M25_RS07415	COG2814	Major facilitator Superfamily
C7M25_RS07420	COG1309	transcriptional regulator
C7M25_RS07425	COG0574	Belongs to the PEP-utilizing enzyme family
C7M25_RS07425	COG3848	Pyruvate phosphate dikinase
C7M25_RS07430	COG4897	Protein conserved in bacteria
C7M25_RS07440	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M25_RS07455	COG3595	metallopeptidase activity
C7M25_RS07460	COG1983	PspC domain protein
C7M25_RS07465	COG1950	PFAM Membrane protein of
C7M25_RS07470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M25_RS07475	COG1309	transcriptional regulator
C7M25_RS07490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M25_RS07510	COG0110	maltose O-acetyltransferase activity
C7M25_RS07515	COG4990	cell redox homeostasis
C7M25_RS07530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M25_RS07555	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M25_RS07555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M25_RS07560	COG1132	(ABC) transporter
C7M25_RS07565	COG0745	RESPONSE REGULATOR receiver
C7M25_RS07570	COG5002	protein histidine kinase activity
C7M25_RS07575	COG0457	Tetratricopeptide repeat
C7M25_RS07580	COG0791	NLP P60 protein
C7M25_RS07580	COG3883	PFAM NLP P60 protein
C7M25_RS07585	COG0492	ferredoxin-NADP+ reductase activity
C7M25_RS07590	COG1051	belongs to the nudix hydrolase family
C7M25_RS07600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M25_RS07610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS07615	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M25_RS07630	COG4290	ribonuclease
C7M25_RS07635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M25_RS07640	COG0288	reversible hydration of carbon dioxide
C7M25_RS07645	COG0659	secondary active sulfate transmembrane transporter activity
C7M25_RS07650	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M25_RS07655	COG1611	Belongs to the LOG family
C7M25_RS07660	COG2814	Major facilitator Superfamily
C7M25_RS07660	COG0477	Major facilitator Superfamily
C7M25_RS07665	COG2828	Protein conserved in bacteria
C7M25_RS07670	COG0583	DNA-binding transcription factor activity
C7M25_RS07680	COG1609	Transcriptional regulator
C7M25_RS07685	COG2223	nitrite transmembrane transporter activity
C7M25_RS07735	COG3479	Phenolic acid decarboxylase
C7M25_RS07740	COG0456	acetyltransferase
C7M25_RS07745	COG2364	Membrane
C7M25_RS07750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M25_RS07760	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M25_RS07765	COG1396	sequence-specific DNA binding
C7M25_RS07770	COG3944	biosynthesis protein
C7M25_RS07775	COG0489	protein tyrosine kinase activity
C7M25_RS07780	COG1086	Polysaccharide biosynthesis protein
C7M25_RS07785	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS07790	COG1215	transferase activity, transferring glycosyl groups
C7M25_RS07795	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS07805	COG1216	Glycosyl transferase, family 2
C7M25_RS07810	COG5039	Polysaccharide pyruvyl transferase
C7M25_RS07815	COG1216	Glycosyl transferase, family 2
C7M25_RS07820	COG2244	polysaccharide biosynthetic process
C7M25_RS07825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M25_RS07830	COG0110	maltose O-acetyltransferase activity
C7M25_RS07835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M25_RS07840	COG5039	Polysaccharide pyruvyl transferase
C7M25_RS07850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M25_RS07855	COG1620	l-lactate permease
C7M25_RS07860	COG2186	Transcriptional regulator
C7M25_RS07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS07890	COG1070	Carbohydrate kinase
C7M25_RS07895	COG1737	Transcriptional regulator
C7M25_RS07905	COG0561	phosphatase activity
C7M25_RS07915	COG1609	Transcriptional regulator
C7M25_RS07925	COG1113	amino acid transport
C7M25_RS07930	COG0697	spore germination
C7M25_RS07935	COG0583	DNA-binding transcription factor activity
C7M25_RS07945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M25_RS07950	COG1609	Transcriptional regulator
C7M25_RS07955	COG2814	Major facilitator Superfamily
C7M25_RS07960	COG2390	Transcriptional regulator
C7M25_RS07965	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M25_RS07970	COG0126	phosphoglycerate kinase activity
C7M25_RS07990	COG2234	aminopeptidase activity
C7M25_RS08000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M25_RS08005	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS08010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M25_RS08025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M25_RS08040	COG0456	acetyltransferase
C7M25_RS08045	COG4640	response to antibiotic
C7M25_RS08050	COG3064	Membrane
C7M25_RS08055	COG2095	MarC family integral membrane protein
C7M25_RS08060	COG1510	regulation of RNA biosynthetic process
C7M25_RS08065	COG0517	IMP dehydrogenase activity
C7M25_RS08065	COG1125	glycine betaine transport
C7M25_RS08070	COG1174	glycine betaine transport
C7M25_RS08075	COG1732	Glycine betaine
C7M25_RS08080	COG1174	glycine betaine transport
C7M25_RS08085	COG1510	regulation of RNA biosynthetic process
C7M25_RS08090	COG0517	IMP dehydrogenase activity
C7M25_RS08090	COG1125	glycine betaine transport
C7M25_RS08095	COG1174	glycine betaine transport
C7M25_RS08100	COG1732	Glycine betaine
C7M25_RS08105	COG1174	glycine betaine transport
C7M25_RS08135	COG1733	regulation of RNA biosynthetic process
C7M25_RS08140	COG1396	sequence-specific DNA binding
C7M25_RS08145	COG1396	sequence-specific DNA binding
C7M25_RS08150	COG1476	TRANSCRIPTIONal
C7M25_RS08155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M25_RS08160	COG1647	Serine aminopeptidase, S33
C7M25_RS08165	COG0557	exoribonuclease II activity
C7M25_RS08180	COG2732	(Barnase) inhibitor
C7M25_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS08190	COG0583	DNA-binding transcription factor activity
C7M25_RS08195	COG0454	-acetyltransferase
C7M25_RS08200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS08205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS08210	COG0765	amino acid transport
C7M25_RS08215	COG0765	amino acid transport
C7M25_RS08220	COG1126	abc transporter atp-binding protein
C7M25_RS08225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M25_RS08230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M25_RS08235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M25_RS08250	COG2814	Major facilitator Superfamily
C7M25_RS08265	COG0673	inositol 2-dehydrogenase activity
C7M25_RS08270	COG1937	Protein conserved in bacteria
C7M25_RS08275	COG2608	mercury ion transmembrane transporter activity
C7M25_RS08280	COG2217	Heavy metal translocating P-type atpase
C7M25_RS08285	COG2217	Heavy metal translocating P-type atpase
C7M25_RS08290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M25_RS08295	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M25_RS08305	COG2860	membrane
C7M25_RS08310	COG3973	AAA domain
C7M25_RS08315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M25_RS08335	COG0656	L-ascorbic acid biosynthetic process
C7M25_RS08340	COG0842	Transport permease protein
C7M25_RS08350	COG1131	(ABC) transporter
C7M25_RS08355	COG3850	Histidine kinase
C7M25_RS08360	COG2197	response regulator
C7M25_RS08365	COG4149	molybdate abc transporter
C7M25_RS08370	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M25_RS08375	COG1910	domain protein
C7M25_RS08380	COG1368	sulfuric ester hydrolase activity
C7M25_RS08385	COG1988	membrane-bound metal-dependent
C7M25_RS08395	COG0531	amino acid
C7M25_RS08400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M25_RS08405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS08410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS08415	COG1120	ATPase activity
C7M25_RS08425	COG2140	Oxalate decarboxylase
C7M25_RS08435	COG1191	sigma factor activity
C7M25_RS08445	COG0745	RESPONSE REGULATOR receiver
C7M25_RS08450	COG2205	protein histidine kinase activity
C7M25_RS08455	COG3386	PFAM SMP-30 Gluconolaconase
C7M25_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS08465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M25_RS08470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M25_RS08475	COG1120	ATPase activity
C7M25_RS08480	COG2096	Adenosyltransferase
C7M25_RS08485	COG2814	Major facilitator Superfamily
C7M25_RS08490	COG4758	membrane
C7M25_RS08495	COG1842	Phage shock protein A
C7M25_RS08500	COG3595	metallopeptidase activity
C7M25_RS08505	COG4758	membrane
C7M25_RS08510	COG4585	Histidine kinase
C7M25_RS08515	COG2197	response regulator
C7M25_RS08525	COG0814	amino acid
C7M25_RS08530	COG0697	spore germination
C7M25_RS08540	COG0114	fumarate hydratase activity
C7M25_RS08545	COG1309	transcriptional regulator
C7M25_RS08555	COG2770	Histidine kinase
C7M25_RS08555	COG2205	protein histidine kinase activity
C7M25_RS08560	COG0745	RESPONSE REGULATOR receiver
C7M25_RS08565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M25_RS08570	COG0783	Belongs to the Dps family
C7M25_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS08590	COG1120	ATPase activity
C7M25_RS08610	COG0583	DNA-binding transcription factor activity
C7M25_RS08615	COG0477	Major facilitator Superfamily
C7M25_RS08620	COG1846	Transcriptional regulator
C7M25_RS08625	COG5577	PFAM Coat F domain
C7M25_RS08645	COG1024	Enoyl-CoA hydratase
C7M25_RS08645	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M25_RS08650	COG0183	Belongs to the thiolase family
C7M25_RS08655	COG1960	acyl-CoA dehydrogenase activity
C7M25_RS08660	COG1393	Belongs to the ArsC family
C7M25_RS08675	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M25_RS08680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS08690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M25_RS08695	COG2011	ABC-type metal ion transport system permease component
C7M25_RS08700	COG1464	Belongs to the NlpA lipoprotein family
C7M25_RS08705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M25_RS08715	COG0396	ATPase activity
C7M25_RS08720	COG0719	Fe-S assembly protein
C7M25_RS08725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M25_RS08730	COG0822	iron-sulfur transferase activity
C7M25_RS08735	COG0719	Fe-S assembly protein
C7M25_RS08740	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS08750	COG2226	methyltransferase
C7M25_RS08755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M25_RS08760	COG0322	excinuclease ABC activity
C7M25_RS08785	COG0789	Transcriptional regulator
C7M25_RS08790	COG2222	sugar isomerase
C7M25_RS08795	COG1653	transport
C7M25_RS08800	COG1175	transmembrane transport
C7M25_RS08805	COG0395	ABC-type sugar transport system, permease component
C7M25_RS08810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M25_RS08815	COG2188	Transcriptional regulator
C7M25_RS08820	COG3842	ATPase activity
C7M25_RS08825	COG2356	endonuclease I
C7M25_RS08830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M25_RS08835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M25_RS08840	COG2814	Major facilitator Superfamily
C7M25_RS08855	COG0457	Tetratricopeptide repeat
C7M25_RS08860	COG2508	Transcriptional regulator
C7M25_RS08875	COG1801	Protein of unknown function DUF72
C7M25_RS08880	COG0730	response to heat
C7M25_RS08885	COG0737	Belongs to the 5'-nucleotidase family
C7M25_RS08895	COG0739	heme binding
C7M25_RS08905	COG4470	Protein conserved in bacteria
C7M25_RS08910	COG2445	Protein of unknown function DUF86
C7M25_RS08915	COG0647	UMP catabolic process
C7M25_RS08920	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M25_RS08925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M25_RS08930	COG0460	homoserine dehydrogenase
C7M25_RS08935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M25_RS08945	COG4946	Tricorn protease homolog
C7M25_RS08945	COG1506	peptidase
C7M25_RS08945	COG0823	Involved in the tonB-independent uptake of proteins
C7M25_RS08950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M25_RS08955	COG4837	Protein of unknown function (DUF1462)
C7M25_RS08960	COG1252	NADH dehydrogenase
C7M25_RS08970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M25_RS08980	COG0316	Belongs to the HesB IscA family
C7M25_RS08985	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M25_RS09010	COG1131	(ABC) transporter
C7M25_RS09035	COG1252	NADH dehydrogenase
C7M25_RS09050	COG3584	3D domain protein
C7M25_RS09055	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M25_RS09065	COG2056	Na+-H+ antiporter family
C7M25_RS09070	COG1268	BioY protein
C7M25_RS09075	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M25_RS09080	COG2819	hydrolase of the alpha beta superfamily
C7M25_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS09090	COG1169	isochorismate synthase
C7M25_RS09095	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M25_RS09100	COG1535	isochorismatase
C7M25_RS09100	COG3433	isochorismatase activity
C7M25_RS09105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS09110	COG3251	PFAM MbtH domain protein
C7M25_RS09115	COG5634	Uncharacterized conserved protein (DUF2278)
C7M25_RS09120	COG0686	Belongs to the AlaDH PNT family
C7M25_RS09125	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M25_RS09125	COG2508	Transcriptional regulator
C7M25_RS09130	COG4842	Belongs to the WXG100 family
C7M25_RS09135	COG5417	Belongs to the EsaB family
C7M25_RS09140	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M25_RS09145	COG0433	COG0433 Predicted ATPase
C7M25_RS09145	COG1674	ftsk spoiiie
C7M25_RS09150	COG1511	domain protein
C7M25_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS09165	COG1418	mRNA catabolic process
C7M25_RS09175	COG0628	permease
C7M25_RS09190	COG5506	Protein of unknown function (DUF1694)
C7M25_RS09195	COG1335	isochorismatase
C7M25_RS09200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M25_RS09205	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M25_RS09220	COG0142	geranyltranstransferase activity
C7M25_RS09230	COG4585	Histidine kinase
C7M25_RS09235	COG2197	response regulator
C7M25_RS09240	COG2050	protein possibly involved in aromatic compounds catabolism
C7M25_RS09245	COG1320	monovalent cation:proton antiporter activity
C7M25_RS09250	COG2212	antiporter activity
C7M25_RS09255	COG1863	multisubunit Na H antiporter MnhE subunit
C7M25_RS09260	COG0651	ATP synthesis coupled electron transport
C7M25_RS09265	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M25_RS09270	COG2111	Na H antiporter
C7M25_RS09275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M25_RS09275	COG2111	Na H antiporter
C7M25_RS09305	COG4565	transcriptional regulatory protein
C7M25_RS09310	COG3290	protein histidine kinase activity
C7M25_RS09320	COG3011	Protein conserved in bacteria
C7M25_RS09325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M25_RS09330	COG2814	Major facilitator Superfamily
C7M25_RS09335	COG5018	Exonuclease
C7M25_RS09345	COG2205	protein histidine kinase activity
C7M25_RS09350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M25_RS09360	COG2267	carboxylic ester hydrolase activity
C7M25_RS09365	COG1522	sequence-specific DNA binding
C7M25_RS09370	COG0436	Aminotransferase
C7M25_RS09375	COG1098	S1 RNA binding domain
C7M25_RS09380	COG2155	Conserved Protein
C7M25_RS09385	COG1979	alcohol dehydrogenase
C7M25_RS09390	COG1979	alcohol dehydrogenase
C7M25_RS09395	COG1335	isochorismatase
C7M25_RS09420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M25_RS09435	COG2738	Putative neutral zinc metallopeptidase
C7M25_RS09440	COG1253	flavin adenine dinucleotide binding
C7M25_RS09445	COG0366	Alpha amylase catalytic
C7M25_RS09450	COG0432	Pfam Uncharacterised protein family UPF0047
C7M25_RS09455	COG2070	2-Nitropropane dioxygenase
C7M25_RS09470	COG0840	transmembrane signaling receptor activity
C7M25_RS09475	COG0840	transmembrane signaling receptor activity
C7M25_RS09480	COG0840	transmembrane signaling receptor activity
C7M25_RS09485	COG0840	transmembrane signaling receptor activity
C7M25_RS09490	COG0693	protein deglycase activity
C7M25_RS09495	COG0673	inositol 2-dehydrogenase activity
C7M25_RS09500	COG0628	permease
C7M25_RS09525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M25_RS09525	COG1017	nitric oxide dioxygenase activity
C7M25_RS09530	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M25_RS09535	COG0569	domain protein
C7M25_RS09545	COG1510	regulation of RNA biosynthetic process
C7M25_RS09555	COG1454	alcohol dehydrogenase
C7M25_RS09565	COG2318	DinB family
C7M25_RS09570	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M25_RS09575	COG2268	Band 7 protein
C7M25_RS09580	COG3859	Proton-coupled thiamine transporter YuaJ
C7M25_RS09705	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M25_RS09710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M25_RS09715	COG1169	isochorismate synthase
C7M25_RS09725	COG0596	Alpha beta hydrolase
C7M25_RS09730	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M25_RS09740	COG4948	Mandelate Racemase Muconate Lactonizing
C7M25_RS09750	COG1294	oxidase, subunit
C7M25_RS09755	COG1271	oxidase subunit
C7M25_RS09765	COG0288	reversible hydration of carbon dioxide
C7M25_RS09790	COG0783	Belongs to the Dps family
C7M25_RS09795	COG4824	toxin secretion phage lysis holin
C7M25_RS09800	COG0494	nUDIX hydrolase
C7M25_RS09805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M25_RS09810	COG1116	anion transmembrane transporter activity
C7M25_RS09815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M25_RS09820	COG1506	peptidase
C7M25_RS09840	COG0367	asparagine synthase
C7M25_RS09845	COG1113	amino acid transport
C7M25_RS09850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M25_RS09855	COG2267	carboxylic ester hydrolase activity
C7M25_RS09870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M25_RS09875	COG1242	4 iron, 4 sulfur cluster binding
C7M25_RS09880	COG0477	Major facilitator Superfamily
C7M25_RS09895	COG1725	Transcriptional regulator
C7M25_RS09900	COG1131	(ABC) transporter
C7M25_RS09920	COG1136	(ABC) transporter
C7M25_RS09925	COG0577	efflux transmembrane transporter activity
C7M25_RS09930	COG0745	RESPONSE REGULATOR receiver
C7M25_RS09935	COG2205	protein histidine kinase activity
C7M25_RS09940	COG1136	(ABC) transporter
C7M25_RS09945	COG0577	efflux transmembrane transporter activity
C7M25_RS09950	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M25_RS09955	COG2814	Major facilitator Superfamily
C7M25_RS09960	COG2202	Pas domain
C7M25_RS09960	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS09975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M25_RS09985	COG1486	melibiose metabolic process
C7M25_RS10015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M25_RS10020	COG2081	HI0933 family
C7M25_RS10025	COG2244	polysaccharide biosynthetic process
C7M25_RS10030	COG1187	pseudouridine synthase activity
C7M25_RS10035	COG1349	DNA-binding transcription factor activity
C7M25_RS10040	COG1131	(ABC) transporter
C7M25_RS10045	COG4473	ABC transporter
C7M25_RS10050	COG2252	PERMEase
C7M25_RS10055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M25_RS10060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M25_RS10065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M25_RS10075	COG1597	lipid kinase activity
C7M25_RS10080	COG0510	thiamine kinase activity
C7M25_RS10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS10100	COG0281	malic enzyme
C7M25_RS10105	COG5584	Small secreted protein
C7M25_RS10110	COG1363	Peptidase, m42
C7M25_RS10120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS10130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M25_RS10135	COG1674	ftsk spoiiie
C7M25_RS10145	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M25_RS10150	COG4980	gas vesicle protein
C7M25_RS10155	COG3118	belongs to the thioredoxin family
C7M25_RS10160	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M25_RS10160	COG1605	Chorismate mutase
C7M25_RS10165	COG1609	Transcriptional regulator
C7M25_RS10170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M25_RS10175	COG1360	Flagellar Motor Protein
C7M25_RS10180	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M25_RS10185	COG0517	IMP dehydrogenase activity
C7M25_RS10190	COG0454	-acetyltransferase
C7M25_RS10195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M25_RS10215	COG1378	Sugar-specific transcriptional regulator TrmB
C7M25_RS10220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M25_RS10235	COG0693	protein deglycase activity
C7M25_RS10250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M25_RS10250	COG1017	nitric oxide dioxygenase activity
C7M25_RS10255	COG0582	viral genome integration into host DNA
C7M25_RS10270	COG0457	Tetratricopeptide repeat
C7M25_RS10285	COG2199	diguanylate cyclase activity
C7M25_RS10285	COG2203	Gaf domain
C7M25_RS10290	COG1956	GAF domain-containing protein
C7M25_RS10295	COG1309	transcriptional regulator
C7M25_RS10300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M25_RS10310	COG1114	Component of the transport system for branched-chain amino acids
C7M25_RS10315	COG1104	cysteine desulfurase activity
C7M25_RS10330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M25_RS10335	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M25_RS10340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M25_RS10345	COG0616	signal peptide processing
C7M25_RS10350	COG1714	RDD family
C7M25_RS10360	COG3874	Sporulation protein YtfJ
C7M25_RS10365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M25_RS10370	COG0827	DNA restriction-modification system
C7M25_RS10380	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M25_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS10405	COG4109	DRTGG domain
C7M25_RS10415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M25_RS10435	COG0587	DNA-directed DNA polymerase activity
C7M25_RS10440	COG0281	malic enzyme
C7M25_RS10460	COG0469	pyruvate kinase activity
C7M25_RS10465	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M25_RS10470	COG0628	permease
C7M25_RS10480	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS10495	COG0372	Belongs to the citrate synthase family
C7M25_RS10500	COG0538	isocitrate dehydrogenase activity
C7M25_RS10510	COG0745	RESPONSE REGULATOR receiver
C7M25_RS10515	COG5002	protein histidine kinase activity
C7M25_RS10520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M25_RS10520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M25_RS10525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M25_RS10530	COG1971	Probably functions as a manganese efflux pump
C7M25_RS10535	COG0237	dephospho-CoA kinase activity
C7M25_RS10540	COG0656	L-ascorbic acid biosynthetic process
C7M25_RS10545	COG2814	Major facilitator Superfamily
C7M25_RS10550	COG1733	regulation of RNA biosynthetic process
C7M25_RS10555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M25_RS10570	COG3611	Membrane attachment protein
C7M25_RS10575	COG1484	DNA-dependent DNA replication
C7M25_RS10580	COG0398	Pfam SNARE associated Golgi protein
C7M25_RS10600	COG3275	phosphorelay sensor kinase activity
C7M25_RS10605	COG3279	Response regulator of the LytR AlgR family
C7M25_RS10610	COG1380	Effector of murein hydrolase LrgA
C7M25_RS10615	COG1346	cytolysis
C7M25_RS10620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M25_RS10635	COG3326	Membrane
C7M25_RS10645	COG1363	Peptidase, m42
C7M25_RS10650	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M25_RS10655	COG2160	L-arabinose isomerase activity
C7M25_RS10660	COG1069	ribulokinase activity
C7M25_RS10665	COG0235	Class ii aldolase
C7M25_RS10670	COG0647	UMP catabolic process
C7M25_RS10680	COG1653	transport
C7M25_RS10685	COG1175	transmembrane transport
C7M25_RS10690	COG0395	ABC-type sugar transport system, permease component
C7M25_RS10695	COG3534	alpha-L-arabinofuranosidase
C7M25_RS10700	COG1966	Carbon starvation protein
C7M25_RS10705	COG0247	lactate metabolic process
C7M25_RS10710	COG0277	FAD linked oxidase domain protein
C7M25_RS10715	COG3835	regulator
C7M25_RS10725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M25_RS10730	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M25_RS10735	COG0072	phenylalanine-tRNA ligase activity
C7M25_RS10735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M25_RS10755	COG1286	toxin biosynthetic process
C7M25_RS10760	COG1796	DNA polymerase
C7M25_RS10760	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M25_RS10770	COG3766	membrane
C7M25_RS10780	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS10785	COG1309	transcriptional regulator
C7M25_RS10790	COG1024	Enoyl-CoA hydratase
C7M25_RS10795	COG2086	electron transfer activity
C7M25_RS10800	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M25_RS10805	COG3534	alpha-L-arabinofuranosidase
C7M25_RS10810	COG3118	belongs to the thioredoxin family
C7M25_RS10820	COG0527	aspartate kinase activity
C7M25_RS10825	COG1719	4-vinyl reductase, 4VR
C7M25_RS10830	COG2009	succinate dehydrogenase
C7M25_RS10835	COG1053	succinate dehydrogenase
C7M25_RS10840	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M25_RS10845	COG0824	Thioesterase
C7M25_RS10850	COG2197	response regulator
C7M25_RS10855	COG1846	Transcriptional regulator
C7M25_RS10865	COG5401	PFAM Sporulation and spore germination
C7M25_RS10875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M25_RS10880	COG0622	Phosphoesterase
C7M25_RS10930	COG0028	Belongs to the TPP enzyme family
C7M25_RS10935	COG0440	acetolactate synthase activity
C7M25_RS10950	COG0473	3-isopropylmalate dehydrogenase activity
C7M25_RS10965	COG1477	protein flavinylation
C7M25_RS10965	COG0457	Tetratricopeptide repeat
C7M25_RS10980	COG1067	ATP-dependent peptidase activity
C7M25_RS10980	COG0470	DNA polymerase III
C7M25_RS10985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M25_RS11005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M25_RS11015	COG1587	Uroporphyrinogen-III synthase
C7M25_RS11020	COG0113	porphobilinogen synthase activity
C7M25_RS11030	COG1388	LysM domain
C7M25_RS11035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M25_RS11045	COG0525	valine-tRNA ligase activity
C7M25_RS11050	COG0285	dihydrofolate synthase activity
C7M25_RS11055	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M25_RS11075	COG1077	Cell shape determining protein MreB Mrl
C7M25_RS11080	COG1792	Involved in formation and maintenance of cell shape
C7M25_RS11085	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M25_RS11095	COG2894	cell division
C7M25_RS11100	COG0739	heme binding
C7M25_RS11105	COG1994	Peptidase M50
C7M25_RS11115	COG2868	ribosomal protein
C7M25_RS11120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M25_RS11125	COG3290	protein histidine kinase activity
C7M25_RS11140	COG0077	Prephenate dehydratase
C7M25_RS11145	COG1827	regulation of RNA biosynthetic process
C7M25_RS11150	COG1104	cysteine desulfurase activity
C7M25_RS11155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M25_RS11160	COG0157	Belongs to the NadC ModD family
C7M25_RS11170	COG1388	LysM domain
C7M25_RS11215	COG1862	Preprotein translocase
C7M25_RS11225	COG2323	membrane
C7M25_RS11230	COG2244	polysaccharide biosynthetic process
C7M25_RS11240	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M25_RS11240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M25_RS11245	COG0490	domain, Protein
C7M25_RS11250	COG5416	Lipopolysaccharide assembly protein A domain
C7M25_RS11255	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M25_RS11255	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M25_RS11265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M25_RS11275	COG3103	Sh3 type 3 domain protein
C7M25_RS11275	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS11275	COG4991	sh3 domain protein
C7M25_RS11300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M25_RS11305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M25_RS11310	COG1959	2 iron, 2 sulfur cluster binding
C7M25_RS11315	COG1104	cysteine desulfurase activity
C7M25_RS11325	COG0457	Tetratricopeptide repeat
C7M25_RS11330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M25_RS11335	COG3881	PFAM PRC-barrel domain
C7M25_RS11350	COG0765	amino acid transport
C7M25_RS11355	COG0765	amino acid transport
C7M25_RS11360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS11365	COG1126	abc transporter atp-binding protein
C7M25_RS11370	COG0628	permease
C7M25_RS11395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M25_RS11425	COG0768	penicillin binding
C7M25_RS11450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M25_RS11455	COG0626	cystathionine gamma-synthase activity
C7M25_RS11465	COG2427	Protein of unknown function (DUF1641)
C7M25_RS11470	COG3383	formate dehydrogenase (NAD+) activity
C7M25_RS11475	COG5609	conserved protein (DUF2294)
C7M25_RS11480	COG2116	formate transmembrane transporter activity
C7M25_RS11490	COG2226	methyltransferase
C7M25_RS11495	COG1309	transcriptional regulator
C7M25_RS11500	COG2124	cytochrome p450
C7M25_RS11500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M25_RS11505	COG2814	Major facilitator Superfamily
C7M25_RS11510	COG0583	DNA-binding transcription factor activity
C7M25_RS11515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M25_RS11525	COG3711	transcriptional antiterminator
C7M25_RS11525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS11530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M25_RS11530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M25_RS11530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS11535	COG1482	cell wall glycoprotein biosynthetic process
C7M25_RS11550	COG0561	phosphatase activity
C7M25_RS11560	COG2318	DinB family
C7M25_RS11565	COG0456	acetyltransferase
C7M25_RS11580	COG0563	adenylate kinase activity
C7M25_RS11590	COG3708	Transcriptional regulator
C7M25_RS11590	COG2207	Transcriptional regulator
C7M25_RS11620	COG0398	Pfam SNARE associated Golgi protein
C7M25_RS11625	COG0726	polysaccharide deacetylase
C7M25_RS11630	COG2755	lipolytic protein G-D-S-L family
C7M25_RS11640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M25_RS11645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M25_RS11650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M25_RS11655	COG1534	Rna-binding protein
C7M25_RS11665	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M25_RS11670	COG0799	negative regulation of ribosome biogenesis
C7M25_RS11675	COG2226	methyltransferase
C7M25_RS11680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M25_RS11685	COG1555	photosystem II stabilization
C7M25_RS11685	COG1596	polysaccharide export
C7M25_RS11690	COG2131	deaminase
C7M25_RS11695	COG0658	competence protein
C7M25_RS11695	COG2333	competence protein COMEC
C7M25_RS11710	COG1466	dna polymerase III delta subunit
C7M25_RS11725	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS11740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M25_RS11770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M25_RS11775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M25_RS11780	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M25_RS11785	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M25_RS11790	COG1610	YqeY-like protein
C7M25_RS11795	COG1030	water channel activity
C7M25_RS11800	COG4864	UPF0365 protein
C7M25_RS11815	COG0561	phosphatase activity
C7M25_RS11820	COG1702	phosphate starvation-inducible protein PhoH
C7M25_RS11825	COG1480	7TM receptor with intracellular HD hydrolase
C7M25_RS11835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M25_RS11840	COG0295	cytidine deaminase activity
C7M25_RS11845	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M25_RS11865	COG0751	glycine-tRNA ligase activity
C7M25_RS11870	COG0517	IMP dehydrogenase activity
C7M25_RS11885	COG0358	DNA primase activity
C7M25_RS11890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M25_RS11895	COG2010	Cytochrome c
C7M25_RS11900	COG2384	SAM-dependent methyltransferase
C7M25_RS11905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M25_RS11920	COG0513	Belongs to the DEAD box helicase family
C7M25_RS11935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS11940	COG0735	belongs to the Fur family
C7M25_RS11945	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M25_RS11950	COG4709	membrane
C7M25_RS11960	COG1388	LysM domain
C7M25_RS11965	COG5521	maltodextrose utilization protein MalA
C7M25_RS11970	COG2839	Protein conserved in bacteria
C7M25_RS11975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M25_RS11980	COG0477	Major facilitator Superfamily
C7M25_RS11990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M25_RS11995	COG0573	inorganic phosphate transmembrane transporter activity
C7M25_RS12000	COG0581	inorganic phosphate transmembrane transporter activity
C7M25_RS12005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M25_RS12010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M25_RS12015	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M25_RS12025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M25_RS12030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M25_RS12040	COG1757	Na H antiporter
C7M25_RS12045	COG4483	Protein conserved in bacteria
C7M25_RS12050	COG1940	carbohydrate kinase activity
C7M25_RS12055	COG2866	Carboxypeptidase
C7M25_RS12065	COG0011	TIGRFAM Protein of
C7M25_RS12075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS12085	COG1393	Belongs to the ArsC family
C7M25_RS12095	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS12100	COG1253	flavin adenine dinucleotide binding
C7M25_RS12105	COG0598	Magnesium transport protein CorA
C7M25_RS12110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M25_RS12115	COG1459	type II secretion system
C7M25_RS12120	COG4537	Required for transformation and DNA binding
C7M25_RS12125	COG4970	Tfp pilus assembly protein FimT
C7M25_RS12135	COG4940	Competence protein ComGF
C7M25_RS12160	COG0681	Belongs to the peptidase S26 family
C7M25_RS12170	COG1396	sequence-specific DNA binding
C7M25_RS12185	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M25_RS12205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M25_RS12220	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M25_RS12230	COG3872	metal-dependent enzyme
C7M25_RS12240	COG0006	proline dipeptidase activity
C7M25_RS12255	COG3854	ATPases associated with a variety of cellular activities
C7M25_RS12295	COG0511	ligase activity, forming carbon-carbon bonds
C7M25_RS12300	COG0439	Biotin carboxylase
C7M25_RS12305	COG1302	Protein conserved in bacteria
C7M25_RS12320	COG1570	exodeoxyribonuclease VII activity
C7M25_RS12330	COG0142	geranyltranstransferase activity
C7M25_RS12340	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M25_RS12350	COG0497	DNA recombination
C7M25_RS12355	COG0750	zinc metalloprotease
C7M25_RS12360	COG0745	RESPONSE REGULATOR receiver
C7M25_RS12365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M25_RS12380	COG1902	pentaerythritol trinitrate reductase activity
C7M25_RS12400	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS12405	COG0584	glycerophosphoryl diester phosphodiesterase
C7M25_RS12410	COG0183	Belongs to the thiolase family
C7M25_RS12415	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M25_RS12420	COG1960	acyl-CoA dehydrogenase activity
C7M25_RS12425	COG0372	Belongs to the citrate synthase family
C7M25_RS12430	COG2079	MmgE PrpD family protein
C7M25_RS12435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M25_RS12445	COG3829	transcription factor binding
C7M25_RS12445	COG3290	protein histidine kinase activity
C7M25_RS12450	COG0280	phosphate acetyltransferase
C7M25_RS12455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M25_RS12460	COG3426	butyrate kinase activity
C7M25_RS12465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M25_RS12470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M25_RS12475	COG0022	dehydrogenase e1 component
C7M25_RS12480	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M25_RS12485	COG1597	lipid kinase activity
C7M25_RS12495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M25_RS12500	COG0765	amino acid transport
C7M25_RS12505	COG1126	abc transporter atp-binding protein
C7M25_RS12510	COG4129	membrane
C7M25_RS12515	COG1376	ErfK ybiS ycfS ynhG family protein
C7M25_RS12525	COG0346	lactoylglutathione lyase activity
C7M25_RS12530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M25_RS12535	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M25_RS12540	COG0706	membrane insertase activity
C7M25_RS12555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M25_RS12560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M25_RS12575	COG0596	Alpha beta hydrolase
C7M25_RS12595	COG0250	Participates in transcription elongation, termination and antitermination
C7M25_RS12600	COG2070	2-Nitropropane dioxygenase
C7M25_RS12600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M25_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS12620	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS12625	COG3321	synthase
C7M25_RS12625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12630	COG0300	oxidoreductase activity
C7M25_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12630	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS12630	COG3321	synthase
C7M25_RS12630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS12635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS12635	COG3321	synthase
C7M25_RS12635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12640	COG0300	oxidoreductase activity
C7M25_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12640	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS12640	COG3321	synthase
C7M25_RS12645	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS12645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12645	COG0300	oxidoreductase activity
C7M25_RS12645	COG3321	synthase
C7M25_RS12650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS12650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS12650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12650	COG3321	synthase
C7M25_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS12655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS12655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS12655	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS12655	COG3321	synthase
C7M25_RS12660	COG2124	cytochrome p450
C7M25_RS12665	COG3425	synthase
C7M25_RS12670	COG1024	Enoyl-CoA hydratase
C7M25_RS12675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M25_RS12680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS12685	COG0300	oxidoreductase activity
C7M25_RS12690	COG3048	D-serine ammonia-lyase activity
C7M25_RS12700	COG0346	lactoylglutathione lyase activity
C7M25_RS12710	COG0628	permease
C7M25_RS12725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M25_RS12730	COG0456	acetyltransferase
C7M25_RS12735	COG2329	Antibiotic biosynthesis monooxygenase
C7M25_RS12740	COG0456	acetyltransferase
C7M25_RS12740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M25_RS12745	COG4918	Iron-sulphur cluster biosynthesis
C7M25_RS12755	COG1073	alpha beta
C7M25_RS12765	COG0667	Aldo Keto reductase
C7M25_RS12775	COG0494	nUDIX hydrolase
C7M25_RS12780	COG1379	DNA repair
C7M25_RS12785	COG1396	sequence-specific DNA binding
C7M25_RS12790	COG0252	asparaginase activity
C7M25_RS12795	COG1027	Aspartate ammonia-lyase
C7M25_RS12800	COG1757	Na H antiporter
C7M25_RS12805	COG0281	malic enzyme
C7M25_RS12820	COG1300	Membrane
C7M25_RS12825	COG0735	belongs to the Fur family
C7M25_RS12835	COG4974	Belongs to the 'phage' integrase family
C7M25_RS12840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M25_RS12845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M25_RS12850	COG1686	Belongs to the peptidase S11 family
C7M25_RS12855	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS12865	COG1191	sigma factor activity
C7M25_RS12885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M25_RS12900	COG0697	spore germination
C7M25_RS12905	COG0019	diaminopimelate decarboxylase activity
C7M25_RS12910	COG4086	secreted protein
C7M25_RS12915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M25_RS12925	COG0681	Belongs to the peptidase S26 family
C7M25_RS12935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M25_RS12935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M25_RS12940	COG0307	riboflavin synthase, alpha
C7M25_RS12955	COG0456	acetyltransferase
C7M25_RS12960	COG1547	Domain of unknown function (DUF309)
C7M25_RS12985	COG1686	Belongs to the peptidase S11 family
C7M25_RS12990	COG2715	membrane protein required for spore maturation
C7M25_RS12995	COG0700	Nucleoside recognition
C7M25_RS13000	COG1187	pseudouridine synthase activity
C7M25_RS13005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS13010	COG1333	cytochrome c biogenesis protein
C7M25_RS13015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M25_RS13020	COG0745	RESPONSE REGULATOR receiver
C7M25_RS13025	COG5002	protein histidine kinase activity
C7M25_RS13030	COG1595	DNA-templated transcription, initiation
C7M25_RS13040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M25_RS13045	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M25_RS13050	COG1141	Ferredoxin
C7M25_RS13055	COG4955	Helix-turn-helix domain
C7M25_RS13060	COG0514	ATP-dependent DNA helicase (RecQ)
C7M25_RS13065	COG1266	CAAX protease self-immunity
C7M25_RS13070	COG1388	LysM domain
C7M25_RS13080	COG1408	metallophosphoesterase
C7M25_RS13085	COG4862	establishment of competence for transformation
C7M25_RS13090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M25_RS13095	COG0492	ferredoxin-NADP+ reductase activity
C7M25_RS13100	COG2339	peptidase activity
C7M25_RS13105	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS13105	COG3773	Cell wall hydrolase
C7M25_RS13110	COG2959	enzyme of heme biosynthesis
C7M25_RS13115	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M25_RS13130	COG0539	negative regulation of cytoplasmic translation
C7M25_RS13170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M25_RS13175	COG0776	regulation of translation
C7M25_RS13190	COG0142	geranyltranstransferase activity
C7M25_RS13200	COG0142	geranyltranstransferase activity
C7M25_RS13205	COG0105	UTP biosynthetic process
C7M25_RS13210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M25_RS13225	COG4401	Chorismate mutase type I
C7M25_RS13230	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M25_RS13265	COG0287	Prephenate dehydrogenase
C7M25_RS13280	COG0457	Tetratricopeptide repeat
C7M25_RS13295	COG0723	plastoquinol--plastocyanin reductase activity
C7M25_RS13300	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M25_RS13305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M25_RS13305	COG2010	Cytochrome c
C7M25_RS13310	COG4347	Protein of unknown function (DUF1405)
C7M25_RS13320	COG2140	Oxalate decarboxylase
C7M25_RS13325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS13330	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M25_RS13345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M25_RS13350	COG0438	transferase activity, transferring glycosyl groups
C7M25_RS13380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M25_RS13380	COG1199	ATP-dependent helicase activity
C7M25_RS13390	COG5353	protein conserved in bacteria
C7M25_RS13395	COG0436	Aminotransferase
C7M25_RS13405	COG3935	DnaD domain protein
C7M25_RS13410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M25_RS13420	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M25_RS13420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M25_RS13460	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M25_RS13465	COG2190	(PTS) system
C7M25_RS13470	COG1111	helicase
C7M25_RS13470	COG1205	dead DEAH box helicase
C7M25_RS13475	COG3359	exonuclease
C7M25_RS13505	COG0116	Belongs to the methyltransferase superfamily
C7M25_RS13520	COG1199	ATP-dependent helicase activity
C7M25_RS13525	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M25_RS13540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M25_RS13545	COG1525	nuclease
C7M25_RS13550	COG4282	regulation of fungal-type cell wall biogenesis
C7M25_RS13560	COG5444	nuclease activity
C7M25_RS13600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M25_RS13605	COG0457	Tetratricopeptide repeat
C7M25_RS13625	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS13625	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS13630	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M25_RS13650	COG0739	heme binding
C7M25_RS13650	COG1196	nuclear chromosome segregation
C7M25_RS13650	COG0741	lytic transglycosylase activity
C7M25_RS13810	COG0776	regulation of translation
C7M25_RS13905	COG3655	Transcriptional regulator
C7M25_RS14015	COG3655	Transcriptional regulator
C7M25_RS14130	COG5484	DNA packaging
C7M25_RS14130	COG3728	DNA packaging
C7M25_RS14140	COG1793	dna ligase
C7M25_RS14145	COG2135	peptidase activity
C7M25_RS14170	COG4195	phage-related replication protein
C7M25_RS14175	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M25_RS14175	COG3420	alginic acid biosynthetic process
C7M25_RS14200	COG2887	Belongs to the helicase family. UvrD subfamily
C7M25_RS14210	COG0305	Participates in initiation and elongation during chromosome replication
C7M25_RS14215	COG0358	DNA primase activity
C7M25_RS14220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M25_RS14225	COG0587	DNA-directed DNA polymerase activity
C7M25_RS14230	COG3584	3D domain protein
C7M25_RS14240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M25_RS14335	COG1780	Probably involved in ribonucleotide reductase function
C7M25_RS14340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M25_RS14370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS14380	COG0756	dUTP diphosphatase activity
C7M25_RS14415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M25_RS14450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M25_RS14480	COG3331	DNA recombination
C7M25_RS14495	COG1335	isochorismatase
C7M25_RS14500	COG2323	membrane
C7M25_RS14520	COG3424	synthase
C7M25_RS14525	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M25_RS14535	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M25_RS14550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M25_RS14560	COG0328	RNA-DNA hybrid ribonuclease activity
C7M25_RS14565	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M25_RS14570	COG0328	RNA-DNA hybrid ribonuclease activity
C7M25_RS14590	COG1278	Cold shock
C7M25_RS14600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M25_RS14610	COG0386	Belongs to the glutathione peroxidase family
C7M25_RS14615	COG1418	mRNA catabolic process
C7M25_RS14620	COG1413	lyase activity
C7M25_RS14635	COG2521	methyltransferase
C7M25_RS14635	COG2136	Putative SAM-dependent methyltransferase
C7M25_RS14650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M25_RS14655	COG0204	Acyl-transferase
C7M25_RS14665	COG1272	protein, Hemolysin III
C7M25_RS14670	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M25_RS14675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M25_RS14685	COG1999	signal sequence binding
C7M25_RS14690	COG2755	lipolytic protein G-D-S-L family
C7M25_RS14695	COG4698	Protein conserved in bacteria
C7M25_RS14700	COG1846	Transcriptional regulator
C7M25_RS14720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M25_RS14725	COG1525	nuclease
C7M25_RS14730	COG4282	regulation of fungal-type cell wall biogenesis
C7M25_RS14735	COG5444	nuclease activity
C7M25_RS14775	COG3391	amine dehydrogenase activity
C7M25_RS14785	COG0457	Tetratricopeptide repeat
C7M25_RS14810	COG3655	Transcriptional regulator
C7M25_RS14870	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS14880	COG0457	Tetratricopeptide repeat
C7M25_RS14885	COG1388	LysM domain
C7M25_RS14910	COG1086	Polysaccharide biosynthesis protein
C7M25_RS14920	COG4641	Protein conserved in bacteria
C7M25_RS14935	COG0463	Glycosyl transferase, family 2
C7M25_RS14940	COG0456	acetyltransferase
C7M25_RS14950	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7M25_RS14955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M25_RS14960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M25_RS14965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M25_RS14970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M25_RS14975	COG0456	acetyltransferase
C7M25_RS14980	COG1509	lysine 2,3-aminomutase activity
C7M25_RS15010	COG0671	phosphoesterase, PA-phosphatase related
C7M25_RS15030	COG1876	peptidase activity
C7M25_RS15040	COG2226	methyltransferase
C7M25_RS15045	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS15045	COG0793	Belongs to the peptidase S41A family
C7M25_RS15050	COG2188	Transcriptional regulator
C7M25_RS15055	COG2723	6-phospho-beta-galactosidase activity
C7M25_RS15065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M25_RS15075	COG0346	lactoylglutathione lyase activity
C7M25_RS15080	COG0400	carboxylic ester hydrolase activity
C7M25_RS15085	COG0778	Nitroreductase
C7M25_RS15090	COG1733	regulation of RNA biosynthetic process
C7M25_RS15100	COG1942	4-Oxalocrotonate Tautomerase
C7M25_RS15115	COG2962	Rard protein
C7M25_RS15125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M25_RS15130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M25_RS15135	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS15140	COG0534	Mate efflux family protein
C7M25_RS15145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M25_RS15150	COG1819	glycosyl
C7M25_RS15155	COG1388	LysM domain
C7M25_RS15155	COG0791	NLP P60 protein
C7M25_RS15160	COG2032	superoxide dismutase activity
C7M25_RS15165	COG0714	Associated with various cellular activities
C7M25_RS15170	COG4548	von Willebrand factor, type A
C7M25_RS15180	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M25_RS15185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS15190	COG0385	Bile acid
C7M25_RS15195	COG0733	neurotransmitter:sodium symporter activity
C7M25_RS15200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M25_RS15205	COG1657	PFAM Prenyltransferase squalene oxidase
C7M25_RS15210	COG1012	belongs to the aldehyde dehydrogenase family
C7M25_RS15240	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M25_RS15255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M25_RS15260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M25_RS15270	COG0514	ATP-dependent DNA helicase (RecQ)
C7M25_RS15275	COG1388	LysM domain
C7M25_RS15275	COG3584	3D domain protein
C7M25_RS15285	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M25_RS15300	COG2322	membrane
C7M25_RS15305	COG0741	lytic transglycosylase activity
C7M25_RS15310	COG0640	Transcriptional regulator
C7M25_RS15320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M25_RS15325	COG1309	transcriptional regulator
C7M25_RS15330	COG2207	Transcriptional regulator
C7M25_RS15330	COG0662	Cupin 2, conserved barrel domain protein
C7M25_RS15335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M25_RS15340	COG5444	nuclease activity
C7M25_RS15370	COG0243	molybdopterin cofactor binding
C7M25_RS15375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M25_RS15380	COG1070	Carbohydrate kinase
C7M25_RS15385	COG2814	Major facilitator Superfamily
C7M25_RS15395	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M25_RS15400	COG0300	oxidoreductase activity
C7M25_RS15420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M25_RS15425	COG0583	DNA-binding transcription factor activity
C7M25_RS15430	COG0070	glutamate synthase
C7M25_RS15430	COG0069	glutamate synthase activity
C7M25_RS15430	COG0067	glutamate synthase
C7M25_RS15435	COG0493	'glutamate synthase
C7M25_RS15440	COG0604	alcohol dehydrogenase
C7M25_RS15450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M25_RS15455	COG0640	Transcriptional regulator
C7M25_RS15460	COG2814	Major facilitator Superfamily
C7M25_RS15465	COG0405	Gamma-glutamyltransferase
C7M25_RS15470	COG0166	Belongs to the GPI family
C7M25_RS15475	COG0582	viral genome integration into host DNA
C7M25_RS15490	COG0534	Mate efflux family protein
C7M25_RS15495	COG2017	converts alpha-aldose to the beta-anomer
C7M25_RS15500	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M25_RS15505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS15510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS15515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS15520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS15525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS15525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M25_RS15535	COG1649	PFAM Uncharacterised BCR, COG1649
C7M25_RS15540	COG1960	acyl-CoA dehydrogenase activity
C7M25_RS15545	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS15550	COG0439	Biotin carboxylase
C7M25_RS15555	COG0511	ligase activity, forming carbon-carbon bonds
C7M25_RS15560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M25_RS15565	COG1024	Enoyl-CoA hydratase
C7M25_RS15570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M25_RS15575	COG0586	Pfam SNARE associated Golgi protein
C7M25_RS15580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M25_RS15585	COG2246	polysaccharide biosynthetic process
C7M25_RS15595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M25_RS15610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M25_RS15615	COG2124	cytochrome p450
C7M25_RS15620	COG2610	gluconate transmembrane transporter activity
C7M25_RS15625	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M25_RS15630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M25_RS15635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS15660	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M25_RS15670	COG0745	RESPONSE REGULATOR receiver
C7M25_RS15675	COG2205	protein histidine kinase activity
C7M25_RS15705	COG0577	efflux transmembrane transporter activity
C7M25_RS15705	COG1136	(ABC) transporter
C7M25_RS15730	COG2271	Major facilitator Superfamily
C7M25_RS15735	COG1609	Transcriptional regulator
C7M25_RS15740	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS15745	COG1312	Catalyzes the dehydration of D-mannonate
C7M25_RS15750	COG0800	Aldolase
C7M25_RS15755	COG1063	alcohol dehydrogenase
C7M25_RS15765	COG1115	amino acid carrier protein
C7M25_RS15775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M25_RS15780	COG0187	DNA topoisomerase II activity
C7M25_RS15785	COG1832	CoA-binding protein
C7M25_RS15795	COG4841	protein insertion into membrane
C7M25_RS15805	COG0824	Thioesterase
C7M25_RS15825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS15830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M25_RS15845	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M25_RS15855	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M25_RS15860	COG2201	protein-glutamate methylesterase activity
C7M25_RS15865	COG0785	Cytochrome C biogenesis protein
C7M25_RS15885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M25_RS15895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M25_RS15925	COG4195	phage-related replication protein
C7M25_RS15930	COG0756	dUTP diphosphatase activity
C7M25_RS15935	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M25_RS15950	COG3397	chitin binding
C7M25_RS15985	COG0456	acetyltransferase
C7M25_RS16010	COG1064	alcohol dehydrogenase
C7M25_RS16025	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M25_RS16045	COG3848	Pyruvate phosphate dikinase
C7M25_RS16045	COG0574	Belongs to the PEP-utilizing enzyme family
C7M25_RS16050	COG1070	Carbohydrate kinase
C7M25_RS16065	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M25_RS16070	COG2211	Major facilitator Superfamily
C7M25_RS16080	COG0457	Tetratricopeptide repeat
C7M25_RS16085	COG0457	Tetratricopeptide repeat
C7M25_RS16115	COG0174	glutamine synthetase
C7M25_RS16120	COG0789	Transcriptional regulator
C7M25_RS16125	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M25_RS16130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M25_RS16135	COG0464	growth
C7M25_RS16145	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS16150	COG4112	unkown
C7M25_RS16155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M25_RS16160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M25_RS16200	COG2076	Multidrug Resistance protein
C7M25_RS16210	COG1764	response to oxidative stress
C7M25_RS16215	COG4195	phage-related replication protein
C7M25_RS16225	COG1404	Belongs to the peptidase S8 family
C7M25_RS16235	COG3619	membrane
C7M25_RS16240	COG3209	COG3209 Rhs family protein
C7M25_RS16245	COG2124	cytochrome p450
C7M25_RS16250	COG3321	synthase
C7M25_RS16250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M25_RS16250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M25_RS16255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS16255	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS16255	COG3321	synthase
C7M25_RS16255	COG4221	oxidoreductase activity
C7M25_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS16260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16260	COG3321	synthase
C7M25_RS16260	COG3321	synthase
C7M25_RS16260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS16260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M25_RS16260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS16260	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS16260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS16265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16265	COG0300	oxidoreductase activity
C7M25_RS16265	COG3321	synthase
C7M25_RS16265	COG4221	oxidoreductase activity
C7M25_RS16270	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS16270	COG0300	oxidoreductase activity
C7M25_RS16270	COG3321	synthase
C7M25_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS16270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS16275	COG1024	Enoyl-CoA hydratase
C7M25_RS16280	COG1024	Enoyl-CoA hydratase
C7M25_RS16285	COG3425	synthase
C7M25_RS16290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16335	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M25_RS16355	COG2359	stage V sporulation protein S
C7M25_RS16360	COG1692	metallophosphoesterase
C7M25_RS16370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M25_RS16385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M25_RS16390	COG1426	Protein conserved in bacteria
C7M25_RS16405	COG0300	oxidoreductase activity
C7M25_RS16410	COG0612	Peptidase, M16
C7M25_RS16415	COG0612	Peptidase, M16
C7M25_RS16420	COG1033	growth of symbiont in host cell
C7M25_RS16420	COG2409	Drug exporters of the RND superfamily
C7M25_RS16425	COG1846	Transcriptional regulator
C7M25_RS16430	COG2814	Major facilitator Superfamily
C7M25_RS16435	COG2188	Transcriptional regulator
C7M25_RS16440	COG4980	gas vesicle protein
C7M25_RS16440	COG1674	ftsk spoiiie
C7M25_RS16450	COG0740	serine-type endopeptidase activity
C7M25_RS16455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M25_RS16465	COG0527	aspartate kinase activity
C7M25_RS16470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M25_RS16475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M25_RS16480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M25_RS16485	COG1873	PFAM PRC-barrel domain
C7M25_RS16490	COG0612	Peptidase, M16
C7M25_RS16495	COG0726	polysaccharide deacetylase
C7M25_RS16510	COG0196	riboflavin kinase activity
C7M25_RS16525	COG1550	Protein conserved in bacteria
C7M25_RS16535	COG1358	cellular component organization or biogenesis
C7M25_RS16540	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M25_RS16545	COG0195	Participates in both transcription termination and antitermination
C7M25_RS16555	COG2176	DNA-directed DNA polymerase activity
C7M25_RS16565	COG0750	zinc metalloprotease
C7M25_RS16575	COG4589	Belongs to the CDS family
C7M25_RS16580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M25_RS16610	COG1191	sigma factor activity
C7M25_RS16620	COG1776	CheC inhibitor of MCP methylation
C7M25_RS16625	COG0835	chemotaxis
C7M25_RS16630	COG0643	Histidine kinase
C7M25_RS16630	COG2198	Histidine kinase
C7M25_RS16635	COG2201	protein-glutamate methylesterase activity
C7M25_RS16640	COG0455	bacterial-type flagellum organization
C7M25_RS16645	COG1419	protein localization to endoplasmic reticulum
C7M25_RS16650	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M25_RS16655	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M25_RS16660	COG1684	flagellar biosynthetic protein fliR
C7M25_RS16665	COG1987	bacterial-type flagellum assembly
C7M25_RS16670	COG1338	Plays a role in the flagellum-specific transport system
C7M25_RS16675	COG3190	flagellar
C7M25_RS16680	COG2201	protein-glutamate methylesterase activity
C7M25_RS16685	COG1776	CheC inhibitor of MCP methylation
C7M25_RS16685	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M25_RS16690	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M25_RS16695	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M25_RS16700	COG1582	Flagellar protein (FlbD)
C7M25_RS16705	COG4786	Flagellar basal body rod
C7M25_RS16710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M25_RS16715	COG3144	bacterial-type flagellum assembly
C7M25_RS16720	COG3334	PFAM MgtE intracellular
C7M25_RS16725	COG2882	bacterial-type flagellum organization
C7M25_RS16730	COG1157	protein secretion by the type III secretion system
C7M25_RS16735	COG1317	bacterial-type flagellum organization
C7M25_RS16740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M25_RS16745	COG1766	The M ring may be actively involved in energy transduction
C7M25_RS16750	COG1677	Flagellar hook-basal body complex protein FliE
C7M25_RS16755	COG1558	bacterial-type flagellum-dependent cell motility
C7M25_RS16760	COG1815	bacterial-type flagellum-dependent cell motility
C7M25_RS16780	COG4974	Belongs to the 'phage' integrase family
C7M25_RS16790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M25_RS16795	COG0758	DNA mediated transformation
C7M25_RS16800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M25_RS16810	COG2257	FlhB HrpN YscU SpaS Family
C7M25_RS16825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M25_RS16850	COG1837	Belongs to the UPF0109 family
C7M25_RS16860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M25_RS16875	COG0552	protein localization to endoplasmic reticulum
C7M25_RS16880	COG1196	nuclear chromosome segregation
C7M25_RS16890	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS16895	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS16900	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M25_RS16915	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M25_RS16920	COG1760	l-serine dehydratase
C7M25_RS16925	COG1760	l-serine dehydratase
C7M25_RS16930	COG1461	Dihydroxyacetone kinase
C7M25_RS16935	COG1302	Protein conserved in bacteria
C7M25_RS16950	COG1564	THIamine pyrophosphokinase
C7M25_RS16955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M25_RS16965	COG0515	serine threonine protein kinase
C7M25_RS16965	COG2815	serine threonine protein kinase
C7M25_RS16970	COG0631	protein serine/threonine phosphatase activity
C7M25_RS16980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M25_RS16980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M25_RS16990	COG0242	peptide deformylase activity
C7M25_RS16995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M25_RS17000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M25_RS17010	COG0194	GDP metabolic process
C7M25_RS17015	COG2052	Domain of unknown function (DUF370)
C7M25_RS17020	COG1561	YicC-like family, N-terminal region
C7M25_RS17025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M25_RS17035	COG1648	precorrin-2 dehydrogenase activity
C7M25_RS17040	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M25_RS17045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M25_RS17060	COG0306	phosphate transporter
C7M25_RS17070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M25_RS17075	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M25_RS17090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M25_RS17095	COG0505	Belongs to the CarA family
C7M25_RS17100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M25_RS17110	COG2233	PERMEase
C7M25_RS17120	COG0564	pseudouridine synthase activity
C7M25_RS17130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M25_RS17135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M25_RS17140	COG3599	regulation of cell shape
C7M25_RS17145	COG2302	S4 RNA-binding domain
C7M25_RS17150	COG0762	integral membrane protein
C7M25_RS17160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M25_RS17170	COG1873	PFAM PRC-barrel domain
C7M25_RS17175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M25_RS17180	COG1119	ATPase activity
C7M25_RS17185	COG1191	sigma factor activity
C7M25_RS17190	COG1191	sigma factor activity
C7M25_RS17200	COG4412	M6 family metalloprotease domain protein
C7M25_RS17200	COG1404	Belongs to the peptidase S8 family
C7M25_RS17205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M25_RS17210	COG0849	cell division
C7M25_RS17215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M25_RS17230	COG0772	Belongs to the SEDS family
C7M25_RS17250	COG0768	penicillin binding
C7M25_RS17260	COG4839	cell division protein FtsL
C7M25_RS17280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M25_RS17295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M25_RS17300	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M25_RS17310	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M25_RS17315	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M25_RS17320	COG3314	Sporulation integral membrane protein YlbJ
C7M25_RS17330	COG0742	ribosomal rna small subunit methyltransferase
C7M25_RS17340	COG3679	Belongs to the UPF0342 family
C7M25_RS17355	COG2340	Cysteine-rich secretory protein family
C7M25_RS17360	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M25_RS17370	COG3336	cytochrome c oxidase
C7M25_RS17375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M25_RS17380	COG1845	cytochrome c oxidase, subunit III
C7M25_RS17385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M25_RS17390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M25_RS17390	COG2010	Cytochrome c
C7M25_RS17405	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M25_RS17410	COG0772	Belongs to the SEDS family
C7M25_RS17420	COG2066	Belongs to the glutaminase family
C7M25_RS17425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M25_RS17430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M25_RS17440	COG4896	Protein conserved in bacteria
C7M25_RS17470	COG1595	DNA-templated transcription, initiation
C7M25_RS17475	COG3227	Zinc metalloprotease (Elastase)
C7M25_RS17485	COG0483	inositol monophosphate 1-phosphatase activity
C7M25_RS17505	COG1982	Orn Lys Arg decarboxylase major
C7M25_RS17520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS17525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M25_RS17530	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M25_RS17535	COG0022	dehydrogenase e1 component
C7M25_RS17540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M25_RS17545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M25_RS17550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS17550	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS17550	COG3321	synthase
C7M25_RS17550	COG4221	oxidoreductase activity
C7M25_RS17555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS17555	COG0300	oxidoreductase activity
C7M25_RS17555	COG4221	oxidoreductase activity
C7M25_RS17555	COG3321	synthase
C7M25_RS17560	COG3321	synthase
C7M25_RS17560	COG4221	oxidoreductase activity
C7M25_RS17560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS17560	COG0300	oxidoreductase activity
C7M25_RS17565	COG0300	oxidoreductase activity
C7M25_RS17565	COG3321	synthase
C7M25_RS17565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS17565	COG4221	oxidoreductase activity
C7M25_RS17570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS17570	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS17570	COG3321	synthase
C7M25_RS17570	COG4221	oxidoreductase activity
C7M25_RS17575	COG0300	oxidoreductase activity
C7M25_RS17575	COG4221	oxidoreductase activity
C7M25_RS17575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M25_RS17575	COG3321	synthase
C7M25_RS17580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M25_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS17580	COG4221	oxidoreductase activity
C7M25_RS17580	COG3321	synthase
C7M25_RS17590	COG0497	DNA recombination
C7M25_RS17600	COG0242	peptide deformylase activity
C7M25_RS17605	COG0561	phosphatase activity
C7M25_RS17615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M25_RS17625	COG0569	domain protein
C7M25_RS17630	COG2105	PFAM AIG2 family protein
C7M25_RS17630	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M25_RS17635	COG3852	Histidine kinase
C7M25_RS17640	COG2002	toxin-antitoxin pair type II binding
C7M25_RS17645	COG1077	Cell shape determining protein MreB Mrl
C7M25_RS17655	COG2309	aminopeptidase activity
C7M25_RS17660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M25_RS17665	COG0488	(ABC) transporter
C7M25_RS17675	COG0681	Belongs to the peptidase S26 family
C7M25_RS17680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M25_RS17680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M25_RS17680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS17685	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M25_RS17690	COG1349	DNA-binding transcription factor activity
C7M25_RS17695	COG0577	efflux transmembrane transporter activity
C7M25_RS17700	COG1136	(ABC) transporter
C7M25_RS17705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M25_RS17715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M25_RS17720	COG0314	molybdopterin synthase activity
C7M25_RS17725	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M25_RS17730	COG0303	'Molybdopterin
C7M25_RS17735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M25_RS17755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS17760	COG0668	transmembrane transport
C7M25_RS17780	COG0716	FMN binding
C7M25_RS17790	COG0716	FMN binding
C7M25_RS17795	COG0583	DNA-binding transcription factor activity
C7M25_RS17800	COG0517	IMP dehydrogenase activity
C7M25_RS17810	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M25_RS17815	COG4703	Protein of unknown function (DUF1797)
C7M25_RS17820	COG2200	EAL domain
C7M25_RS17830	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS17835	COG1408	metallophosphoesterase
C7M25_RS17840	COG1376	ErfK ybiS ycfS ynhG family protein
C7M25_RS17845	COG2814	Major facilitator Superfamily
C7M25_RS17855	COG0784	Response regulator, receiver
C7M25_RS17855	COG0835	chemotaxis
C7M25_RS17860	COG0436	Aminotransferase
C7M25_RS17865	COG4191	Histidine kinase
C7M25_RS17870	COG0768	penicillin binding
C7M25_RS17875	COG2340	Cysteine-rich secretory protein family
C7M25_RS17880	COG2084	Dehydrogenase
C7M25_RS17885	COG0840	transmembrane signaling receptor activity
C7M25_RS17890	COG1533	DNA photolyase activity
C7M25_RS17900	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M25_RS17905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M25_RS17910	COG2190	(PTS) system
C7M25_RS17910	COG1263	PTS System
C7M25_RS17910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M25_RS17915	COG3711	transcriptional antiterminator
C7M25_RS17920	COG1609	Transcriptional regulator
C7M25_RS17925	COG0006	proline dipeptidase activity
C7M25_RS17930	COG2217	Heavy metal translocating P-type atpase
C7M25_RS17935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M25_RS17940	COG2244	polysaccharide biosynthetic process
C7M25_RS17945	COG3773	Cell wall hydrolase
C7M25_RS17955	COG4873	Protein conserved in bacteria
C7M25_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS17975	COG1733	regulation of RNA biosynthetic process
C7M25_RS17985	COG0602	queuosine metabolic process
C7M25_RS17990	COG0720	synthase
C7M25_RS18005	COG3949	Membrane
C7M25_RS18010	COG0542	response to heat
C7M25_RS18015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M25_RS18020	COG1360	Flagellar Motor Protein
C7M25_RS18025	COG1846	Transcriptional regulator
C7M25_RS18030	COG3852	Histidine kinase
C7M25_RS18060	COG0436	Aminotransferase
C7M25_RS18065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M25_RS18080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M25_RS18085	COG5002	protein histidine kinase activity
C7M25_RS18090	COG3594	Acyltransferase
C7M25_RS18100	COG2323	membrane
C7M25_RS18105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M25_RS18135	COG1191	sigma factor activity
C7M25_RS18140	COG0861	Integral membrane protein TerC family
C7M25_RS18145	COG0586	Pfam SNARE associated Golgi protein
C7M25_RS18150	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M25_RS18155	COG1793	dna ligase
C7M25_RS18155	COG3285	dna ligase
C7M25_RS18160	COG0726	polysaccharide deacetylase
C7M25_RS18165	COG1846	Transcriptional regulator
C7M25_RS18180	COG0789	Transcriptional regulator
C7M25_RS18185	COG2239	Acts as a magnesium transporter
C7M25_RS18200	COG3858	chitin binding
C7M25_RS18200	COG1388	LysM domain
C7M25_RS18205	COG4721	ABC-type cobalt transport system, permease component
C7M25_RS18210	COG1122	ATPase activity
C7M25_RS18215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M25_RS18220	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M25_RS18225	COG1404	Belongs to the peptidase S8 family
C7M25_RS18235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M25_RS18240	COG2814	Major facilitator Superfamily
C7M25_RS18250	COG0463	Glycosyl transferase, family 2
C7M25_RS18250	COG0457	Tetratricopeptide repeat
C7M25_RS18265	COG1764	response to oxidative stress
C7M25_RS18270	COG1846	Transcriptional regulator
C7M25_RS18275	COG1764	response to oxidative stress
C7M25_RS18285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M25_RS18290	COG0788	formyltetrahydrofolate deformylase activity
C7M25_RS18295	COG2076	Multidrug Resistance protein
C7M25_RS18300	COG2076	Multidrug Resistance protein
C7M25_RS18305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M25_RS18310	COG1607	acyl-coa hydrolase
C7M25_RS18315	COG1834	amidinotransferase
C7M25_RS18320	COG2706	6-phosphogluconolactonase activity
C7M25_RS18325	COG4608	Belongs to the ABC transporter superfamily
C7M25_RS18330	COG0791	NLP P60 protein
C7M25_RS18335	COG4948	Mandelate Racemase Muconate Lactonizing
C7M25_RS18340	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M25_RS18345	COG4166	transmembrane transport
C7M25_RS18350	COG0444	Belongs to the ABC transporter superfamily
C7M25_RS18355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M25_RS18360	COG0601	transmembrane transport
C7M25_RS18365	COG2362	D-Aminopeptidase
C7M25_RS18370	COG0477	Major facilitator Superfamily
C7M25_RS18375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M25_RS18380	COG0463	Glycosyl transferase, family 2
C7M25_RS18385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M25_RS18390	COG0346	lactoylglutathione lyase activity
C7M25_RS18395	COG0531	amino acid
C7M25_RS18400	COG1392	Phosphate transport regulator
C7M25_RS18405	COG0306	phosphate transporter
C7M25_RS18420	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS18420	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS18460	COG3778	Protein conserved in bacteria
C7M25_RS18465	COG3299	homolog of phage Mu protein gp47
C7M25_RS18470	COG3628	GPW Gp25 family protein
C7M25_RS18480	COG4193	domain, Protein
C7M25_RS18485	COG1652	LysM domain
C7M25_RS18490	COG5412	phage tail tape measure protein
C7M25_RS18490	COG3953	SLT domain
C7M25_RS18490	COG5412	phage tail tape measure protein
C7M25_RS18490	COG3953	SLT domain
C7M25_RS18490	COG5412	phage tail tape measure protein
C7M25_RS18490	COG3953	SLT domain
C7M25_RS18540	COG4653	Phage capsid family
C7M25_RS18545	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M25_RS18550	COG5518	Phage portal protein
C7M25_RS18555	COG1783	phage Terminase large subunit
C7M25_RS18560	COG3728	DNA packaging
C7M25_RS18560	COG5484	DNA packaging
C7M25_RS18565	COG1595	DNA-templated transcription, initiation
C7M25_RS18580	COG1484	DNA-dependent DNA replication
C7M25_RS18585	COG1522	sequence-specific DNA binding
C7M25_RS18595	COG1396	sequence-specific DNA binding
C7M25_RS18600	COG2856	Zn peptidase
C7M25_RS18605	COG4195	phage-related replication protein
C7M25_RS18615	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M25_RS18615	COG1388	LysM domain
C7M25_RS18615	COG3409	Peptidoglycan-binding domain 1 protein
C7M25_RS18625	COG0457	Tetratricopeptide repeat
C7M25_RS18630	COG2318	DinB family
C7M25_RS18635	COG0730	response to heat
C7M25_RS18645	COG1131	(ABC) transporter
C7M25_RS18650	COG2205	protein histidine kinase activity
C7M25_RS18650	COG2770	Histidine kinase
C7M25_RS18655	COG0745	RESPONSE REGULATOR receiver
C7M25_RS18660	COG2721	sulfolactate sulfo-lyase activity
C7M25_RS18665	COG0246	Mannitol dehydrogenase
C7M25_RS18670	COG1609	Transcriptional regulator
C7M25_RS18675	COG2211	Major facilitator Superfamily
C7M25_RS18685	COG1252	NADH dehydrogenase
C7M25_RS18695	COG4297	protein containing double-stranded beta helix domain
C7M25_RS18700	COG0697	spore germination
C7M25_RS18705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M25_RS18710	COG0390	transport system, permease component
C7M25_RS18715	COG1587	Uroporphyrinogen-III synthase
C7M25_RS18725	COG1819	glycosyl
C7M25_RS18730	COG2124	cytochrome p450
C7M25_RS18735	COG2427	Protein of unknown function (DUF1641)
C7M25_RS18740	COG3383	formate dehydrogenase (NAD+) activity
C7M25_RS18750	COG2205	protein histidine kinase activity
C7M25_RS18765	COG1285	pathogenesis
C7M25_RS18795	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M25_RS18800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS18800	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M25_RS18805	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M25_RS18810	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M25_RS18815	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M25_RS18825	COG1846	Transcriptional regulator
C7M25_RS18835	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M25_RS18840	COG2367	Beta-lactamase
C7M25_RS18845	COG0346	lactoylglutathione lyase activity
C7M25_RS18855	COG5444	nuclease activity
C7M25_RS18985	COG4974	Belongs to the 'phage' integrase family
C7M25_RS19005	COG0626	cystathionine gamma-synthase activity
C7M25_RS19010	COG0626	cystathionine gamma-synthase activity
C7M25_RS19015	COG2382	esterase
C7M25_RS19025	COG2153	protein acetylation
C7M25_RS19035	COG1131	(ABC) transporter
C7M25_RS19055	COG0210	DNA helicase
C7M25_RS19110	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M25_RS19115	COG0351	phosphomethylpyrimidine kinase
C7M25_RS19120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M25_RS19130	COG2104	thiamine diphosphate biosynthetic process
C7M25_RS19135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M25_RS19140	COG0352	thiamine-phosphate diphosphorylase activity
C7M25_RS19145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M25_RS19150	COG0475	glutathione-regulated potassium exporter activity
C7M25_RS19150	COG0569	domain protein
C7M25_RS19160	COG0564	pseudouridine synthase activity
C7M25_RS19165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M25_RS19170	COG2357	RelA SpoT domain protein
C7M25_RS19180	COG4116	CYTH
C7M25_RS19185	COG0741	lytic transglycosylase activity
C7M25_RS19190	COG2346	COG2346, Truncated hemoglobins
C7M25_RS19200	COG1164	Oligoendopeptidase f
C7M25_RS19205	COG4469	Competence protein
C7M25_RS19210	COG4862	establishment of competence for transformation
C7M25_RS19215	COG0861	Integral membrane protein TerC family
C7M25_RS19220	COG1393	Belongs to the ArsC family
C7M25_RS19225	COG0456	acetyltransferase
C7M25_RS19235	COG4608	Belongs to the ABC transporter superfamily
C7M25_RS19240	COG0444	Belongs to the ABC transporter superfamily
C7M25_RS19245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M25_RS19255	COG4166	transmembrane transport
C7M25_RS19260	COG0180	Tryptophanyl-tRNA synthetase
C7M25_RS19270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M25_RS19275	COG0601	transmembrane transport
C7M25_RS19285	COG4608	Belongs to the ABC transporter superfamily
C7M25_RS19290	COG0444	Belongs to the ABC transporter superfamily
C7M25_RS19295	COG5504	Zn-dependent protease
C7M25_RS19300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M25_RS19305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M25_RS19320	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M25_RS19330	COG2267	carboxylic ester hydrolase activity
C7M25_RS19345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M25_RS19350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M25_RS19355	COG0505	Belongs to the CarA family
C7M25_RS19360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M25_RS19380	COG2271	Major facilitator Superfamily
C7M25_RS19385	COG0277	FAD linked oxidase domain protein
C7M25_RS19395	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M25_RS19400	COG1073	alpha beta
C7M25_RS19405	COG0561	phosphatase activity
C7M25_RS19420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M25_RS19425	COG1307	EDD domain protein, DegV family
C7M25_RS19435	COG2124	cytochrome p450
C7M25_RS19440	COG0840	transmembrane signaling receptor activity
C7M25_RS19450	COG2996	Protein conserved in bacteria
C7M25_RS19460	COG0646	methionine synthase
C7M25_RS19460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M25_RS19465	COG2153	protein acetylation
C7M25_RS19470	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M25_RS19475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M25_RS19480	COG1279	arginine transmembrane transporter activity
C7M25_RS19485	COG2318	DinB family
C7M25_RS19490	COG1917	Cupin 2, conserved barrel domain protein
C7M25_RS19490	COG2207	Transcriptional regulator
C7M25_RS19495	COG0534	Mate efflux family protein
C7M25_RS19500	COG1562	ergosterol biosynthetic process
C7M25_RS19505	COG0367	asparagine synthase
C7M25_RS19520	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M25_RS19560	COG1403	HNH endonuclease
C7M25_RS19565	COG0419	ATPase involved in DNA repair
C7M25_RS19570	COG0420	3'-5' exonuclease activity
C7M25_RS19585	COG2323	membrane
C7M25_RS19590	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M25_RS19600	COG2814	Major facilitator Superfamily
C7M25_RS19605	COG3180	Ammonia monooxygenase
C7M25_RS19610	COG1846	Transcriptional regulator
C7M25_RS19615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M25_RS19620	COG0681	Belongs to the peptidase S26 family
C7M25_RS19625	COG0398	Pfam SNARE associated Golgi protein
C7M25_RS19640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M25_RS19665	COG5646	InterPro IPR014922
C7M25_RS19675	COG4903	ComK protein
C7M25_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS19690	COG0723	plastoquinol--plastocyanin reductase activity
C7M25_RS19690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M25_RS19695	COG0840	transmembrane signaling receptor activity
C7M25_RS19700	COG1268	BioY protein
C7M25_RS19705	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS19710	COG0183	Belongs to the thiolase family
C7M25_RS19715	COG0406	alpha-ribazole phosphatase activity
C7M25_RS19720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M25_RS19730	COG1404	Belongs to the peptidase S8 family
C7M25_RS19735	COG0501	Belongs to the peptidase M48B family
C7M25_RS19745	COG0318	PFAM AMP-dependent synthetase and ligase
C7M25_RS19750	COG0702	epimerase
C7M25_RS19755	COG0095	Lipoate-protein ligase
C7M25_RS19760	COG1234	tRNA 3'-trailer cleavage
C7M25_RS19770	COG1301	dicarboxylic acid transport
C7M25_RS19775	COG1363	Peptidase, m42
C7M25_RS19785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M25_RS19790	COG1511	domain protein
C7M25_RS19795	COG1309	transcriptional regulator
C7M25_RS19815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M25_RS19820	COG2329	Antibiotic biosynthesis monooxygenase
C7M25_RS19825	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M25_RS19830	COG1473	amidohydrolase
C7M25_RS19840	COG4473	ABC transporter
C7M25_RS19845	COG1131	(ABC) transporter
C7M25_RS19850	COG0537	adenosine 5'-monophosphoramidase activity
C7M25_RS19855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M25_RS19870	COG4980	gas vesicle protein
C7M25_RS19905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M25_RS19920	COG4717	serine-type aminopeptidase activity
C7M25_RS19925	COG0420	3'-5' exonuclease activity
C7M25_RS19930	COG1668	transmembrane transport
C7M25_RS19935	COG4152	abc transporter atp-binding protein
C7M25_RS19945	COG1024	Enoyl-CoA hydratase
C7M25_RS19955	COG0490	domain, Protein
C7M25_RS19960	COG0475	glutathione-regulated potassium exporter activity
C7M25_RS19970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M25_RS19975	COG0561	phosphatase activity
C7M25_RS19980	COG4335	DNA alkylation repair
C7M25_RS19995	COG0189	ligase activity
C7M25_RS20000	COG0189	ligase activity
C7M25_RS20015	COG0702	epimerase
C7M25_RS20020	COG1132	(ABC) transporter
C7M25_RS20025	COG1132	(ABC) transporter
C7M25_RS20030	COG0589	response to stress
C7M25_RS20040	COG3226	Transcriptional regulator
C7M25_RS20045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M25_RS20050	COG0726	polysaccharide deacetylase
C7M25_RS20055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M25_RS20060	COG0668	transmembrane transport
C7M25_RS20070	COG0584	glycerophosphoryl diester phosphodiesterase
C7M25_RS20075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M25_RS20080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M25_RS20085	COG1253	flavin adenine dinucleotide binding
C7M25_RS20090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M25_RS20095	COG0436	Aminotransferase
C7M25_RS20100	COG0789	Transcriptional regulator
C7M25_RS20105	COG1253	flavin adenine dinucleotide binding
C7M25_RS20110	COG0204	Acyl-transferase
C7M25_RS20115	COG1595	DNA-templated transcription, initiation
C7M25_RS20130	COG0733	neurotransmitter:sodium symporter activity
C7M25_RS20135	COG0531	amino acid
C7M25_RS20140	COG1028	Short-chain dehydrogenase reductase Sdr
C7M25_RS20145	COG0372	Belongs to the citrate synthase family
C7M25_RS20150	COG0583	DNA-binding transcription factor activity
C7M25_RS20155	COG0791	NLP P60 protein
C7M25_RS20155	COG1388	LysM domain
C7M25_RS20160	COG1785	Belongs to the alkaline phosphatase family
C7M25_RS20165	COG2719	SpoVR family
C7M25_RS20170	COG0668	transmembrane transport
C7M25_RS20175	COG1959	2 iron, 2 sulfur cluster binding
C7M25_RS20180	COG1388	LysM domain
C7M25_RS20180	COG0791	NLP P60 protein
C7M25_RS20195	COG0431	NADPH-dependent FMN reductase
C7M25_RS20200	COG2197	response regulator
C7M25_RS20205	COG2203	Gaf domain
C7M25_RS20205	COG4585	Histidine kinase
C7M25_RS20210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M25_RS20215	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M25_RS20225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M25_RS20230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M25_RS20235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M25_RS20240	COG3153	acetyltransferase
C7M25_RS20240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M25_RS20245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M25_RS20250	COG0517	IMP dehydrogenase activity
C7M25_RS20260	COG0564	pseudouridine synthase activity
C7M25_RS20265	COG3764	Sortase (surface protein transpeptidase)
C7M25_RS20270	COG4085	toxin activity
C7M25_RS20270	COG1525	nuclease
C7M25_RS20270	COG0737	Belongs to the 5'-nucleotidase family
C7M25_RS20275	COG5577	PFAM Coat F domain
C7M25_RS20295	COG1823	symporter activity
C7M25_RS20300	COG3706	GGDEF domain
C7M25_RS20305	COG1464	Belongs to the NlpA lipoprotein family
C7M25_RS20310	COG1278	Cold shock
C7M25_RS20315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M25_RS20320	COG1131	(ABC) transporter
C7M25_RS20325	COG1131	(ABC) transporter
C7M25_RS20330	COG1725	Transcriptional regulator
C7M25_RS20345	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M25_RS20350	COG2814	Major facilitator Superfamily
C7M25_RS20355	COG1566	PFAM secretion protein HlyD family protein
C7M25_RS20360	COG1846	Transcriptional regulator