locus-tag	class	description
DBK22_RS00010	COG4129	membrane
DBK22_RS00020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DBK22_RS00025	COG0735	belongs to the Fur family
DBK22_RS00135	COG1757	Na H antiporter
DBK22_RS00140	COG3340	Belongs to the peptidase S51 family
DBK22_RS00150	COG0277	FAD linked oxidase domain protein
DBK22_RS00160	COG0747	negative chemotaxis
DBK22_RS00165	COG0601	transmembrane transport
DBK22_RS00170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBK22_RS00175	COG0444	Belongs to the ABC transporter superfamily
DBK22_RS00180	COG4608	Belongs to the ABC transporter superfamily
DBK22_RS00185	COG0753	catalase activity
DBK22_RS00195	COG1116	anion transmembrane transporter activity
DBK22_RS00200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBK22_RS00205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBK22_RS00225	COG1476	TRANSCRIPTIONal
DBK22_RS00235	COG3382	B3 4 domain protein
DBK22_RS00240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DBK22_RS00250	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DBK22_RS00255	COG0789	Transcriptional regulator
DBK22_RS00260	COG1664	Polymer-forming cytoskeletal
DBK22_RS00265	COG1664	Polymer-forming cytoskeletal
DBK22_RS00270	COG2766	serine protein kinase
DBK22_RS00280	COG1846	Transcriptional regulator
DBK22_RS00285	COG1566	PFAM secretion protein HlyD family protein
DBK22_RS00290	COG2814	Major facilitator Superfamily
DBK22_RS00295	COG0655	NAD(P)H dehydrogenase (quinone) activity
DBK22_RS00310	COG1725	Transcriptional regulator
DBK22_RS00315	COG1131	(ABC) transporter
DBK22_RS00320	COG1131	(ABC) transporter
DBK22_RS00325	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DBK22_RS00330	COG1278	Cold shock
DBK22_RS00335	COG1464	Belongs to the NlpA lipoprotein family
DBK22_RS00340	COG3706	GGDEF domain
DBK22_RS00345	COG1823	symporter activity
DBK22_RS00365	COG5577	PFAM Coat F domain
DBK22_RS00370	COG1525	nuclease
DBK22_RS00370	COG0737	Belongs to the 5'-nucleotidase family
DBK22_RS00370	COG4085	toxin activity
DBK22_RS00375	COG3764	Sortase (surface protein transpeptidase)
DBK22_RS00380	COG0564	pseudouridine synthase activity
DBK22_RS00390	COG0517	IMP dehydrogenase activity
DBK22_RS00395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DBK22_RS00400	COG3153	acetyltransferase
DBK22_RS00400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBK22_RS00405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBK22_RS00410	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DBK22_RS00415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DBK22_RS00425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBK22_RS00430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBK22_RS00435	COG4585	Histidine kinase
DBK22_RS00435	COG2203	Gaf domain
DBK22_RS00440	COG2197	response regulator
DBK22_RS00445	COG0431	NADPH-dependent FMN reductase
DBK22_RS00460	COG0791	NLP P60 protein
DBK22_RS00460	COG1388	LysM domain
DBK22_RS00465	COG1959	2 iron, 2 sulfur cluster binding
DBK22_RS00470	COG0668	transmembrane transport
DBK22_RS00475	COG2719	SpoVR family
DBK22_RS00480	COG1785	Belongs to the alkaline phosphatase family
DBK22_RS00485	COG1388	LysM domain
DBK22_RS00485	COG0791	NLP P60 protein
DBK22_RS00490	COG0583	DNA-binding transcription factor activity
DBK22_RS00495	COG0372	Belongs to the citrate synthase family
DBK22_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS00505	COG0531	amino acid
DBK22_RS00510	COG0733	neurotransmitter:sodium symporter activity
DBK22_RS00525	COG1595	DNA-templated transcription, initiation
DBK22_RS00530	COG0204	Acyl-transferase
DBK22_RS00535	COG1253	flavin adenine dinucleotide binding
DBK22_RS00540	COG0789	Transcriptional regulator
DBK22_RS00545	COG0436	Aminotransferase
DBK22_RS00550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBK22_RS00555	COG1253	flavin adenine dinucleotide binding
DBK22_RS00560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBK22_RS00565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBK22_RS00570	COG0584	glycerophosphoryl diester phosphodiesterase
DBK22_RS00580	COG0668	transmembrane transport
DBK22_RS00585	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DBK22_RS00590	COG0726	polysaccharide deacetylase
DBK22_RS00595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS00600	COG3226	Transcriptional regulator
DBK22_RS00610	COG0589	response to stress
DBK22_RS00615	COG1132	(ABC) transporter
DBK22_RS00620	COG1132	(ABC) transporter
DBK22_RS00625	COG0702	epimerase
DBK22_RS00640	COG0189	ligase activity
DBK22_RS00645	COG0189	ligase activity
DBK22_RS00660	COG4335	DNA alkylation repair
DBK22_RS00665	COG0561	phosphatase activity
DBK22_RS00670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBK22_RS00680	COG0475	glutathione-regulated potassium exporter activity
DBK22_RS00685	COG0490	domain, Protein
DBK22_RS00695	COG1024	Enoyl-CoA hydratase
DBK22_RS00705	COG4152	abc transporter atp-binding protein
DBK22_RS00710	COG1668	transmembrane transport
DBK22_RS00715	COG0420	3'-5' exonuclease activity
DBK22_RS00720	COG4717	serine-type aminopeptidase activity
DBK22_RS00735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBK22_RS00770	COG4980	gas vesicle protein
DBK22_RS00785	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBK22_RS00790	COG0537	adenosine 5'-monophosphoramidase activity
DBK22_RS00795	COG1131	(ABC) transporter
DBK22_RS00800	COG4473	ABC transporter
DBK22_RS00810	COG1473	amidohydrolase
DBK22_RS00815	COG3069	C4-dicarboxylate transmembrane transporter activity
DBK22_RS00820	COG2329	Antibiotic biosynthesis monooxygenase
DBK22_RS00825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBK22_RS00845	COG1309	transcriptional regulator
DBK22_RS00850	COG1511	domain protein
DBK22_RS00855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBK22_RS00865	COG1363	Peptidase, m42
DBK22_RS00870	COG1301	dicarboxylic acid transport
DBK22_RS00880	COG1234	tRNA 3'-trailer cleavage
DBK22_RS00885	COG0095	Lipoate-protein ligase
DBK22_RS00890	COG0702	epimerase
DBK22_RS00895	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS00905	COG0501	Belongs to the peptidase M48B family
DBK22_RS00910	COG1404	Belongs to the peptidase S8 family
DBK22_RS00920	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBK22_RS00925	COG0406	alpha-ribazole phosphatase activity
DBK22_RS00930	COG0183	Belongs to the thiolase family
DBK22_RS00935	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS00940	COG1268	BioY protein
DBK22_RS00945	COG0840	transmembrane signaling receptor activity
DBK22_RS00950	COG0723	plastoquinol--plastocyanin reductase activity
DBK22_RS00950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBK22_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS00965	COG4903	ComK protein
DBK22_RS00975	COG5646	InterPro IPR014922
DBK22_RS01000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBK22_RS01015	COG0398	Pfam SNARE associated Golgi protein
DBK22_RS01020	COG0681	Belongs to the peptidase S26 family
DBK22_RS01025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBK22_RS01030	COG1846	Transcriptional regulator
DBK22_RS01035	COG3180	Ammonia monooxygenase
DBK22_RS01040	COG2814	Major facilitator Superfamily
DBK22_RS01050	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DBK22_RS01055	COG2323	membrane
DBK22_RS01070	COG0420	3'-5' exonuclease activity
DBK22_RS01075	COG0419	ATPase involved in DNA repair
DBK22_RS01080	COG1403	HNH endonuclease
DBK22_RS01120	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBK22_RS01140	COG0367	asparagine synthase
DBK22_RS01145	COG1562	ergosterol biosynthetic process
DBK22_RS01150	COG0534	Mate efflux family protein
DBK22_RS01155	COG1917	Cupin 2, conserved barrel domain protein
DBK22_RS01155	COG2207	Transcriptional regulator
DBK22_RS01160	COG2318	DinB family
DBK22_RS01165	COG1279	arginine transmembrane transporter activity
DBK22_RS01170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS01175	COG1357	PFAM Pentapeptide repeats (8 copies)
DBK22_RS01180	COG2153	protein acetylation
DBK22_RS01185	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DBK22_RS01185	COG0646	methionine synthase
DBK22_RS01195	COG2996	Protein conserved in bacteria
DBK22_RS01205	COG0840	transmembrane signaling receptor activity
DBK22_RS01210	COG2124	cytochrome p450
DBK22_RS01220	COG1307	EDD domain protein, DegV family
DBK22_RS01225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS01240	COG0561	phosphatase activity
DBK22_RS01245	COG1073	alpha beta
DBK22_RS01250	COG2151	metal-sulfur cluster biosynthetic enzyme
DBK22_RS01260	COG0277	FAD linked oxidase domain protein
DBK22_RS01265	COG2271	Major facilitator Superfamily
DBK22_RS01285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBK22_RS01290	COG0505	Belongs to the CarA family
DBK22_RS01295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DBK22_RS01300	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DBK22_RS01315	COG2267	carboxylic ester hydrolase activity
DBK22_RS01325	COG1744	ABC transporter substrate-binding protein PnrA-like
DBK22_RS01340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBK22_RS01345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBK22_RS01350	COG5504	Zn-dependent protease
DBK22_RS01355	COG0444	Belongs to the ABC transporter superfamily
DBK22_RS01360	COG4608	Belongs to the ABC transporter superfamily
DBK22_RS01370	COG0601	transmembrane transport
DBK22_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBK22_RS01385	COG0180	Tryptophanyl-tRNA synthetase
DBK22_RS01390	COG4166	transmembrane transport
DBK22_RS01395	COG0601	transmembrane transport
DBK22_RS01400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBK22_RS01405	COG0444	Belongs to the ABC transporter superfamily
DBK22_RS01410	COG4608	Belongs to the ABC transporter superfamily
DBK22_RS01420	COG0456	acetyltransferase
DBK22_RS01425	COG1393	Belongs to the ArsC family
DBK22_RS01430	COG0861	Integral membrane protein TerC family
DBK22_RS01435	COG4862	establishment of competence for transformation
DBK22_RS01440	COG4469	Competence protein
DBK22_RS01445	COG1164	Oligoendopeptidase f
DBK22_RS01455	COG2346	COG2346, Truncated hemoglobins
DBK22_RS01460	COG0741	lytic transglycosylase activity
DBK22_RS01465	COG4116	CYTH
DBK22_RS01475	COG2357	RelA SpoT domain protein
DBK22_RS01480	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBK22_RS01485	COG0564	pseudouridine synthase activity
DBK22_RS01495	COG0569	domain protein
DBK22_RS01495	COG0475	glutathione-regulated potassium exporter activity
DBK22_RS01500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DBK22_RS01505	COG0352	thiamine-phosphate diphosphorylase activity
DBK22_RS01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBK22_RS01515	COG2104	thiamine diphosphate biosynthetic process
DBK22_RS01525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBK22_RS01530	COG0351	phosphomethylpyrimidine kinase
DBK22_RS01535	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DBK22_RS01590	COG0210	DNA helicase
DBK22_RS01610	COG1131	(ABC) transporter
DBK22_RS01620	COG2153	protein acetylation
DBK22_RS01630	COG2382	esterase
DBK22_RS01635	COG0626	cystathionine gamma-synthase activity
DBK22_RS01640	COG0626	cystathionine gamma-synthase activity
DBK22_RS01690	COG0135	phosphoribosylanthranilate isomerase activity
DBK22_RS01700	COG0346	lactoylglutathione lyase activity
DBK22_RS01705	COG2367	Beta-lactamase
DBK22_RS01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DBK22_RS01720	COG1846	Transcriptional regulator
DBK22_RS01730	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DBK22_RS01735	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBK22_RS01740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DBK22_RS01745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS01745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS01750	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBK22_RS01780	COG1285	pathogenesis
DBK22_RS01795	COG2205	protein histidine kinase activity
DBK22_RS01805	COG3383	formate dehydrogenase (NAD+) activity
DBK22_RS01810	COG2427	Protein of unknown function (DUF1641)
DBK22_RS01815	COG2124	cytochrome p450
DBK22_RS01820	COG1819	glycosyl
DBK22_RS01830	COG1587	Uroporphyrinogen-III synthase
DBK22_RS01835	COG0390	transport system, permease component
DBK22_RS01840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBK22_RS01845	COG0697	spore germination
DBK22_RS01850	COG4297	protein containing double-stranded beta helix domain
DBK22_RS01860	COG1252	NADH dehydrogenase
DBK22_RS01870	COG2211	Major facilitator Superfamily
DBK22_RS01875	COG1609	Transcriptional regulator
DBK22_RS01880	COG0246	Mannitol dehydrogenase
DBK22_RS01885	COG2721	sulfolactate sulfo-lyase activity
DBK22_RS01890	COG0745	RESPONSE REGULATOR receiver
DBK22_RS01895	COG2770	Histidine kinase
DBK22_RS01895	COG2205	protein histidine kinase activity
DBK22_RS01915	COG0730	response to heat
DBK22_RS01920	COG2318	DinB family
DBK22_RS01925	COG0457	Tetratricopeptide repeat
DBK22_RS01935	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS01935	COG1388	LysM domain
DBK22_RS01935	COG5632	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS01945	COG4195	phage-related replication protein
DBK22_RS01950	COG2856	Zn peptidase
DBK22_RS01955	COG1396	sequence-specific DNA binding
DBK22_RS01965	COG1522	sequence-specific DNA binding
DBK22_RS01970	COG1484	DNA-dependent DNA replication
DBK22_RS01985	COG1595	DNA-templated transcription, initiation
DBK22_RS01990	COG5484	DNA packaging
DBK22_RS01990	COG3728	DNA packaging
DBK22_RS01995	COG1783	phage Terminase large subunit
DBK22_RS02000	COG5518	Phage portal protein
DBK22_RS02005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DBK22_RS02010	COG4653	Phage capsid family
DBK22_RS02060	COG3953	SLT domain
DBK22_RS02060	COG5412	phage tail tape measure protein
DBK22_RS02065	COG1652	LysM domain
DBK22_RS02070	COG4193	domain, Protein
DBK22_RS02080	COG3628	GPW Gp25 family protein
DBK22_RS02085	COG3299	homolog of phage Mu protein gp47
DBK22_RS02090	COG3778	Protein conserved in bacteria
DBK22_RS02130	COG5632	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS02130	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS02145	COG0306	phosphate transporter
DBK22_RS02150	COG1392	Phosphate transport regulator
DBK22_RS02155	COG0531	amino acid
DBK22_RS02160	COG0346	lactoylglutathione lyase activity
DBK22_RS02165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBK22_RS02170	COG0463	Glycosyl transferase, family 2
DBK22_RS02175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBK22_RS02180	COG0477	Major facilitator Superfamily
DBK22_RS02185	COG2362	D-Aminopeptidase
DBK22_RS02190	COG0601	transmembrane transport
DBK22_RS02195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBK22_RS02200	COG0444	Belongs to the ABC transporter superfamily
DBK22_RS02205	COG4166	transmembrane transport
DBK22_RS02210	COG1619	proteins homologs of microcin C7 resistance protein MccF
DBK22_RS02215	COG4948	Mandelate Racemase Muconate Lactonizing
DBK22_RS02220	COG0791	NLP P60 protein
DBK22_RS02225	COG4608	Belongs to the ABC transporter superfamily
DBK22_RS02230	COG2706	6-phosphogluconolactonase activity
DBK22_RS02235	COG1834	amidinotransferase
DBK22_RS02240	COG1607	acyl-coa hydrolase
DBK22_RS02245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBK22_RS02250	COG2076	Multidrug Resistance protein
DBK22_RS02255	COG2076	Multidrug Resistance protein
DBK22_RS02260	COG0788	formyltetrahydrofolate deformylase activity
DBK22_RS02265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBK22_RS02275	COG1764	response to oxidative stress
DBK22_RS02280	COG1846	Transcriptional regulator
DBK22_RS02285	COG1764	response to oxidative stress
DBK22_RS02300	COG0457	Tetratricopeptide repeat
DBK22_RS02300	COG0463	Glycosyl transferase, family 2
DBK22_RS02310	COG2814	Major facilitator Superfamily
DBK22_RS02315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBK22_RS02325	COG1404	Belongs to the peptidase S8 family
DBK22_RS02330	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS02335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBK22_RS02340	COG1122	ATPase activity
DBK22_RS02345	COG4721	ABC-type cobalt transport system, permease component
DBK22_RS02350	COG3858	chitin binding
DBK22_RS02350	COG1388	LysM domain
DBK22_RS02365	COG2239	Acts as a magnesium transporter
DBK22_RS02370	COG0789	Transcriptional regulator
DBK22_RS02385	COG1846	Transcriptional regulator
DBK22_RS02390	COG0726	polysaccharide deacetylase
DBK22_RS02395	COG3285	dna ligase
DBK22_RS02395	COG1793	dna ligase
DBK22_RS02400	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DBK22_RS02405	COG0586	Pfam SNARE associated Golgi protein
DBK22_RS02410	COG0861	Integral membrane protein TerC family
DBK22_RS02415	COG1191	sigma factor activity
DBK22_RS02440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBK22_RS02445	COG2323	membrane
DBK22_RS02455	COG3594	Acyltransferase
DBK22_RS02460	COG5002	protein histidine kinase activity
DBK22_RS02465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBK22_RS02480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DBK22_RS02485	COG0436	Aminotransferase
DBK22_RS02515	COG3852	Histidine kinase
DBK22_RS02520	COG1846	Transcriptional regulator
DBK22_RS02525	COG1360	Flagellar Motor Protein
DBK22_RS02530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DBK22_RS02535	COG0542	response to heat
DBK22_RS02540	COG3949	Membrane
DBK22_RS02555	COG0720	synthase
DBK22_RS02560	COG0602	queuosine metabolic process
DBK22_RS02570	COG1733	regulation of RNA biosynthetic process
DBK22_RS02575	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS02590	COG4873	Protein conserved in bacteria
DBK22_RS02600	COG3773	Cell wall hydrolase
DBK22_RS02605	COG2244	polysaccharide biosynthetic process
DBK22_RS02610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS02615	COG2217	Heavy metal translocating P-type atpase
DBK22_RS02620	COG0006	proline dipeptidase activity
DBK22_RS02625	COG1609	Transcriptional regulator
DBK22_RS02630	COG3711	transcriptional antiterminator
DBK22_RS02635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS02635	COG2190	(PTS) system
DBK22_RS02635	COG1263	PTS System
DBK22_RS02640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS02645	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBK22_RS02655	COG1533	DNA photolyase activity
DBK22_RS02660	COG0840	transmembrane signaling receptor activity
DBK22_RS02665	COG2084	Dehydrogenase
DBK22_RS02670	COG2340	Cysteine-rich secretory protein family
DBK22_RS02675	COG0768	penicillin binding
DBK22_RS02680	COG4191	Histidine kinase
DBK22_RS02685	COG0436	Aminotransferase
DBK22_RS02690	COG0835	chemotaxis
DBK22_RS02690	COG0784	Response regulator, receiver
DBK22_RS02700	COG2814	Major facilitator Superfamily
DBK22_RS02705	COG1376	ErfK ybiS ycfS ynhG family protein
DBK22_RS02710	COG1408	metallophosphoesterase
DBK22_RS02715	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS02725	COG2200	EAL domain
DBK22_RS02730	COG4703	Protein of unknown function (DUF1797)
DBK22_RS02735	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DBK22_RS02745	COG0517	IMP dehydrogenase activity
DBK22_RS02750	COG0583	DNA-binding transcription factor activity
DBK22_RS02755	COG0716	FMN binding
DBK22_RS02765	COG0716	FMN binding
DBK22_RS02785	COG0668	transmembrane transport
DBK22_RS02790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS02810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBK22_RS02815	COG0303	'Molybdopterin
DBK22_RS02820	COG1763	Mo-molybdopterin cofactor biosynthetic process
DBK22_RS02825	COG0314	molybdopterin synthase activity
DBK22_RS02830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DBK22_RS02840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DBK22_RS02845	COG1136	(ABC) transporter
DBK22_RS02850	COG0577	efflux transmembrane transporter activity
DBK22_RS02855	COG1349	DNA-binding transcription factor activity
DBK22_RS02860	COG1105	Belongs to the carbohydrate kinase PfkB family
DBK22_RS02865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBK22_RS02865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBK22_RS02865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS02870	COG0681	Belongs to the peptidase S26 family
DBK22_RS02880	COG0488	(ABC) transporter
DBK22_RS02885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBK22_RS02890	COG2309	aminopeptidase activity
DBK22_RS02900	COG1077	Cell shape determining protein MreB Mrl
DBK22_RS02905	COG2002	toxin-antitoxin pair type II binding
DBK22_RS02910	COG3852	Histidine kinase
DBK22_RS02915	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DBK22_RS02915	COG2105	PFAM AIG2 family protein
DBK22_RS02920	COG0569	domain protein
DBK22_RS02930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBK22_RS02940	COG0561	phosphatase activity
DBK22_RS02945	COG0242	peptide deformylase activity
DBK22_RS02955	COG0497	DNA recombination
DBK22_RS02965	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DBK22_RS02970	COG0022	dehydrogenase e1 component
DBK22_RS02975	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBK22_RS02980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBK22_RS02985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS03000	COG1982	Orn Lys Arg decarboxylase major
DBK22_RS03020	COG0483	inositol monophosphate 1-phosphatase activity
DBK22_RS03030	COG3227	Zinc metalloprotease (Elastase)
DBK22_RS03065	COG4896	Protein conserved in bacteria
DBK22_RS03075	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DBK22_RS03080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DBK22_RS03085	COG2066	Belongs to the glutaminase family
DBK22_RS03095	COG0772	Belongs to the SEDS family
DBK22_RS03100	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DBK22_RS03115	COG2010	Cytochrome c
DBK22_RS03115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DBK22_RS03120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DBK22_RS03125	COG1845	cytochrome c oxidase, subunit III
DBK22_RS03130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DBK22_RS03135	COG3336	cytochrome c oxidase
DBK22_RS03145	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DBK22_RS03150	COG2340	Cysteine-rich secretory protein family
DBK22_RS03165	COG3679	Belongs to the UPF0342 family
DBK22_RS03180	COG0742	ribosomal rna small subunit methyltransferase
DBK22_RS03190	COG3314	Sporulation integral membrane protein YlbJ
DBK22_RS03195	COG1752	Esterase of the alpha-beta hydrolase superfamily
DBK22_RS03200	COG3480	Lon protease (S16) C-terminal proteolytic domain
DBK22_RS03210	COG1399	metal-binding, possibly nucleic acid-binding protein
DBK22_RS03215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DBK22_RS03230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DBK22_RS03250	COG4839	cell division protein FtsL
DBK22_RS03260	COG0768	penicillin binding
DBK22_RS03280	COG0772	Belongs to the SEDS family
DBK22_RS03295	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DBK22_RS03300	COG0849	cell division
DBK22_RS03305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBK22_RS03310	COG4412	M6 family metalloprotease domain protein
DBK22_RS03310	COG1404	Belongs to the peptidase S8 family
DBK22_RS03320	COG1191	sigma factor activity
DBK22_RS03325	COG1191	sigma factor activity
DBK22_RS03330	COG1119	ATPase activity
DBK22_RS03335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBK22_RS03340	COG1873	PFAM PRC-barrel domain
DBK22_RS03350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DBK22_RS03360	COG0762	integral membrane protein
DBK22_RS03365	COG2302	S4 RNA-binding domain
DBK22_RS03370	COG3599	regulation of cell shape
DBK22_RS03375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBK22_RS03380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DBK22_RS03390	COG0564	pseudouridine synthase activity
DBK22_RS03400	COG2233	PERMEase
DBK22_RS03410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DBK22_RS03415	COG0505	Belongs to the CarA family
DBK22_RS03420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DBK22_RS03435	COG0284	orotidine-5'-phosphate decarboxylase activity
DBK22_RS03440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBK22_RS03450	COG0306	phosphate transporter
DBK22_RS03465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DBK22_RS03470	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DBK22_RS03475	COG1648	precorrin-2 dehydrogenase activity
DBK22_RS03485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DBK22_RS03490	COG1561	YicC-like family, N-terminal region
DBK22_RS03495	COG2052	Domain of unknown function (DUF370)
DBK22_RS03500	COG0194	GDP metabolic process
DBK22_RS03510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBK22_RS03515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBK22_RS03520	COG0242	peptide deformylase activity
DBK22_RS03530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DBK22_RS03530	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBK22_RS03540	COG0631	protein serine/threonine phosphatase activity
DBK22_RS03545	COG2815	serine threonine protein kinase
DBK22_RS03545	COG0515	serine threonine protein kinase
DBK22_RS03555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBK22_RS03560	COG1564	THIamine pyrophosphokinase
DBK22_RS03575	COG1302	Protein conserved in bacteria
DBK22_RS03580	COG1461	Dihydroxyacetone kinase
DBK22_RS03585	COG1760	l-serine dehydratase
DBK22_RS03590	COG1760	l-serine dehydratase
DBK22_RS03595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DBK22_RS03610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBK22_RS03615	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS03620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS03630	COG1196	nuclear chromosome segregation
DBK22_RS03635	COG0552	protein localization to endoplasmic reticulum
DBK22_RS03650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DBK22_RS03660	COG1837	Belongs to the UPF0109 family
DBK22_RS03685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DBK22_RS03700	COG2257	FlhB HrpN YscU SpaS Family
DBK22_RS03710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DBK22_RS03715	COG0758	DNA mediated transformation
DBK22_RS03720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBK22_RS03730	COG4974	Belongs to the 'phage' integrase family
DBK22_RS03750	COG1815	bacterial-type flagellum-dependent cell motility
DBK22_RS03755	COG1558	bacterial-type flagellum-dependent cell motility
DBK22_RS03760	COG1677	Flagellar hook-basal body complex protein FliE
DBK22_RS03765	COG1766	The M ring may be actively involved in energy transduction
DBK22_RS03770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DBK22_RS03775	COG1317	bacterial-type flagellum organization
DBK22_RS03780	COG1157	protein secretion by the type III secretion system
DBK22_RS03785	COG2882	bacterial-type flagellum organization
DBK22_RS03790	COG3334	PFAM MgtE intracellular
DBK22_RS03795	COG3144	bacterial-type flagellum assembly
DBK22_RS03800	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DBK22_RS03805	COG4786	Flagellar basal body rod
DBK22_RS03810	COG1582	Flagellar protein (FlbD)
DBK22_RS03815	COG1580	Controls the rotational direction of flagella during chemotaxis
DBK22_RS03820	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DBK22_RS03825	COG1776	CheC inhibitor of MCP methylation
DBK22_RS03825	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DBK22_RS03830	COG2201	protein-glutamate methylesterase activity
DBK22_RS03835	COG3190	flagellar
DBK22_RS03840	COG1338	Plays a role in the flagellum-specific transport system
DBK22_RS03845	COG1987	bacterial-type flagellum assembly
DBK22_RS03850	COG1684	flagellar biosynthetic protein fliR
DBK22_RS03855	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DBK22_RS03860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DBK22_RS03865	COG1419	protein localization to endoplasmic reticulum
DBK22_RS03870	COG0455	bacterial-type flagellum organization
DBK22_RS03875	COG2201	protein-glutamate methylesterase activity
DBK22_RS03880	COG0643	Histidine kinase
DBK22_RS03880	COG2198	Histidine kinase
DBK22_RS03885	COG0835	chemotaxis
DBK22_RS03890	COG1776	CheC inhibitor of MCP methylation
DBK22_RS03900	COG1191	sigma factor activity
DBK22_RS03930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBK22_RS03935	COG4589	Belongs to the CDS family
DBK22_RS03945	COG0750	zinc metalloprotease
DBK22_RS03955	COG2176	DNA-directed DNA polymerase activity
DBK22_RS03965	COG0195	Participates in both transcription termination and antitermination
DBK22_RS03970	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DBK22_RS03975	COG1358	cellular component organization or biogenesis
DBK22_RS03985	COG1550	Protein conserved in bacteria
DBK22_RS04000	COG0196	riboflavin kinase activity
DBK22_RS04015	COG0726	polysaccharide deacetylase
DBK22_RS04020	COG0612	Peptidase, M16
DBK22_RS04025	COG1873	PFAM PRC-barrel domain
DBK22_RS04030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBK22_RS04035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DBK22_RS04040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DBK22_RS04045	COG0527	aspartate kinase activity
DBK22_RS04055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBK22_RS04060	COG0740	serine-type endopeptidase activity
DBK22_RS04070	COG4980	gas vesicle protein
DBK22_RS04070	COG1674	ftsk spoiiie
DBK22_RS04075	COG2188	Transcriptional regulator
DBK22_RS04080	COG2814	Major facilitator Superfamily
DBK22_RS04085	COG1846	Transcriptional regulator
DBK22_RS04090	COG2409	Drug exporters of the RND superfamily
DBK22_RS04090	COG1033	growth of symbiont in host cell
DBK22_RS04095	COG0612	Peptidase, M16
DBK22_RS04100	COG0612	Peptidase, M16
DBK22_RS04105	COG0300	oxidoreductase activity
DBK22_RS04120	COG1426	Protein conserved in bacteria
DBK22_RS04125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBK22_RS04140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DBK22_RS04150	COG1692	metallophosphoesterase
DBK22_RS04155	COG2359	stage V sporulation protein S
DBK22_RS04175	COG4550	Control of competence regulator ComK, YlbF/YmcA
DBK22_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS04245	COG3425	synthase
DBK22_RS04250	COG1024	Enoyl-CoA hydratase
DBK22_RS04255	COG1024	Enoyl-CoA hydratase
DBK22_RS04260	COG3321	synthase
DBK22_RS04260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04260	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS04260	COG0300	oxidoreductase activity
DBK22_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04265	COG4221	oxidoreductase activity
DBK22_RS04265	COG3321	synthase
DBK22_RS04265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS04265	COG0300	oxidoreductase activity
DBK22_RS04270	COG3321	synthase
DBK22_RS04270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04270	COG3321	synthase
DBK22_RS04270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS04270	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS04275	COG4221	oxidoreductase activity
DBK22_RS04275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04275	COG3321	synthase
DBK22_RS04280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS04280	COG3321	synthase
DBK22_RS04280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBK22_RS04280	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DBK22_RS04285	COG2124	cytochrome p450
DBK22_RS04290	COG3209	COG3209 Rhs family protein
DBK22_RS04295	COG3619	membrane
DBK22_RS04305	COG1404	Belongs to the peptidase S8 family
DBK22_RS04315	COG4195	phage-related replication protein
DBK22_RS04320	COG1764	response to oxidative stress
DBK22_RS04330	COG2076	Multidrug Resistance protein
DBK22_RS04370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBK22_RS04375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBK22_RS04380	COG4112	unkown
DBK22_RS04385	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS04395	COG0464	growth
DBK22_RS04400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBK22_RS04405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DBK22_RS04410	COG0789	Transcriptional regulator
DBK22_RS04415	COG0174	glutamine synthetase
DBK22_RS04425	COG2211	Major facilitator Superfamily
DBK22_RS04430	COG3507	Belongs to the glycosyl hydrolase 43 family
DBK22_RS04445	COG1070	Carbohydrate kinase
DBK22_RS04450	COG0574	Belongs to the PEP-utilizing enzyme family
DBK22_RS04450	COG3848	Pyruvate phosphate dikinase
DBK22_RS04475	COG2318	DinB family
DBK22_RS04480	COG1064	alcohol dehydrogenase
DBK22_RS04505	COG0456	acetyltransferase
DBK22_RS04540	COG3397	chitin binding
DBK22_RS04560	COG5434	Belongs to the glycosyl hydrolase 28 family
DBK22_RS04565	COG0756	dUTP diphosphatase activity
DBK22_RS04570	COG4195	phage-related replication protein
DBK22_RS04600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DBK22_RS04610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DBK22_RS04630	COG0785	Cytochrome C biogenesis protein
DBK22_RS04635	COG2201	protein-glutamate methylesterase activity
DBK22_RS04640	COG4846	Membrane protein involved in cytochrome C biogenesis
DBK22_RS04650	COG0071	Belongs to the small heat shock protein (HSP20) family
DBK22_RS04665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DBK22_RS04670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS04690	COG0824	Thioesterase
DBK22_RS04700	COG4841	protein insertion into membrane
DBK22_RS04710	COG1832	CoA-binding protein
DBK22_RS04715	COG0187	DNA topoisomerase II activity
DBK22_RS04720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBK22_RS04730	COG1115	amino acid carrier protein
DBK22_RS04740	COG1063	alcohol dehydrogenase
DBK22_RS04745	COG0800	Aldolase
DBK22_RS04750	COG1312	Catalyzes the dehydration of D-mannonate
DBK22_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04760	COG1609	Transcriptional regulator
DBK22_RS04765	COG2271	Major facilitator Superfamily
DBK22_RS04790	COG1136	(ABC) transporter
DBK22_RS04790	COG0577	efflux transmembrane transporter activity
DBK22_RS04820	COG2205	protein histidine kinase activity
DBK22_RS04825	COG0745	RESPONSE REGULATOR receiver
DBK22_RS04835	COG3507	Belongs to the glycosyl hydrolase 43 family
DBK22_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS04865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBK22_RS04870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DBK22_RS04875	COG2610	gluconate transmembrane transporter activity
DBK22_RS04880	COG2124	cytochrome p450
DBK22_RS04885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DBK22_RS04900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBK22_RS04910	COG2246	polysaccharide biosynthetic process
DBK22_RS04920	COG0586	Pfam SNARE associated Golgi protein
DBK22_RS04925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBK22_RS04930	COG1024	Enoyl-CoA hydratase
DBK22_RS04935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBK22_RS04940	COG0511	ligase activity, forming carbon-carbon bonds
DBK22_RS04945	COG0439	Biotin carboxylase
DBK22_RS04950	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS04955	COG1960	acyl-CoA dehydrogenase activity
DBK22_RS04960	COG1649	PFAM Uncharacterised BCR, COG1649
DBK22_RS04970	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DBK22_RS04970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS04995	COG2027	D-alanyl-D-alanine carboxypeptidase
DBK22_RS05000	COG2017	converts alpha-aldose to the beta-anomer
DBK22_RS05005	COG0534	Mate efflux family protein
DBK22_RS05020	COG5444	nuclease activity
DBK22_RS05035	COG5632	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS05035	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS05040	COG4824	toxin secretion phage lysis holin
DBK22_RS05060	COG5434	Belongs to the glycosyl hydrolase 28 family
DBK22_RS05065	COG1705	Flagellar rod assembly protein muramidase FlgJ
DBK22_RS05065	COG1388	LysM domain
DBK22_RS05135	COG1802	Transcriptional regulator
DBK22_RS05135	COG4626	Terminase
DBK22_RS05170	COG0582	viral genome integration into host DNA
DBK22_RS05175	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DBK22_RS05275	COG0582	viral genome integration into host DNA
DBK22_RS05280	COG0166	Belongs to the GPI family
DBK22_RS05285	COG0405	Gamma-glutamyltransferase
DBK22_RS05290	COG2814	Major facilitator Superfamily
DBK22_RS05295	COG0640	Transcriptional regulator
DBK22_RS05300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBK22_RS05310	COG0604	alcohol dehydrogenase
DBK22_RS05320	COG0493	'glutamate synthase
DBK22_RS05325	COG0067	glutamate synthase
DBK22_RS05325	COG0069	glutamate synthase activity
DBK22_RS05325	COG0070	glutamate synthase
DBK22_RS05330	COG0583	DNA-binding transcription factor activity
DBK22_RS05335	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DBK22_RS05365	COG0300	oxidoreductase activity
DBK22_RS05370	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DBK22_RS05380	COG2814	Major facilitator Superfamily
DBK22_RS05385	COG1070	Carbohydrate kinase
DBK22_RS05390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBK22_RS05395	COG0243	molybdopterin cofactor binding
DBK22_RS05430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBK22_RS05435	COG2207	Transcriptional regulator
DBK22_RS05435	COG0662	Cupin 2, conserved barrel domain protein
DBK22_RS05440	COG1309	transcriptional regulator
DBK22_RS05445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS05455	COG0640	Transcriptional regulator
DBK22_RS05460	COG0741	lytic transglycosylase activity
DBK22_RS05465	COG2322	membrane
DBK22_RS05480	COG1619	proteins homologs of microcin C7 resistance protein MccF
DBK22_RS05490	COG1388	LysM domain
DBK22_RS05490	COG3584	3D domain protein
DBK22_RS05495	COG0514	ATP-dependent DNA helicase (RecQ)
DBK22_RS05505	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DBK22_RS05510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DBK22_RS05525	COG0071	Belongs to the small heat shock protein (HSP20) family
DBK22_RS05555	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS05560	COG1657	PFAM Prenyltransferase squalene oxidase
DBK22_RS05565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DBK22_RS05570	COG0733	neurotransmitter:sodium symporter activity
DBK22_RS05575	COG0385	Bile acid
DBK22_RS05580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS05585	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBK22_RS05595	COG4548	von Willebrand factor, type A
DBK22_RS05600	COG0714	Associated with various cellular activities
DBK22_RS05605	COG2032	superoxide dismutase activity
DBK22_RS05610	COG1388	LysM domain
DBK22_RS05610	COG0791	NLP P60 protein
DBK22_RS05615	COG1819	glycosyl
DBK22_RS05620	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DBK22_RS05625	COG0534	Mate efflux family protein
DBK22_RS05630	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS05635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBK22_RS05640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBK22_RS05650	COG2962	Rard protein
DBK22_RS05665	COG1942	4-Oxalocrotonate Tautomerase
DBK22_RS05675	COG1733	regulation of RNA biosynthetic process
DBK22_RS05680	COG0778	Nitroreductase
DBK22_RS05685	COG0400	carboxylic ester hydrolase activity
DBK22_RS05690	COG0346	lactoylglutathione lyase activity
DBK22_RS05700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBK22_RS05710	COG2723	6-phospho-beta-galactosidase activity
DBK22_RS05715	COG2188	Transcriptional regulator
DBK22_RS05720	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS05720	COG0793	Belongs to the peptidase S41A family
DBK22_RS05725	COG2226	methyltransferase
DBK22_RS05735	COG1876	peptidase activity
DBK22_RS05755	COG0671	phosphoesterase, PA-phosphatase related
DBK22_RS05785	COG1509	lysine 2,3-aminomutase activity
DBK22_RS05790	COG0456	acetyltransferase
DBK22_RS05795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBK22_RS05800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DBK22_RS05805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DBK22_RS05810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DBK22_RS05815	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DBK22_RS05825	COG0456	acetyltransferase
DBK22_RS05830	COG0463	Glycosyl transferase, family 2
DBK22_RS05845	COG4641	Protein conserved in bacteria
DBK22_RS05855	COG1086	Polysaccharide biosynthesis protein
DBK22_RS05875	COG1388	LysM domain
DBK22_RS05880	COG0457	Tetratricopeptide repeat
DBK22_RS05890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBK22_RS05910	COG5444	nuclease activity
DBK22_RS05915	COG4282	regulation of fungal-type cell wall biogenesis
DBK22_RS05920	COG1525	nuclease
DBK22_RS05925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DBK22_RS05945	COG1846	Transcriptional regulator
DBK22_RS05950	COG4698	Protein conserved in bacteria
DBK22_RS05955	COG2755	lipolytic protein G-D-S-L family
DBK22_RS05960	COG1999	signal sequence binding
DBK22_RS05970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DBK22_RS05975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DBK22_RS05980	COG1272	protein, Hemolysin III
DBK22_RS05985	COG0204	Acyl-transferase
DBK22_RS05990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DBK22_RS06005	COG2521	methyltransferase
DBK22_RS06005	COG2136	Putative SAM-dependent methyltransferase
DBK22_RS06020	COG1413	lyase activity
DBK22_RS06025	COG1418	mRNA catabolic process
DBK22_RS06030	COG0386	Belongs to the glutathione peroxidase family
DBK22_RS06040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBK22_RS06050	COG1278	Cold shock
DBK22_RS06070	COG0328	RNA-DNA hybrid ribonuclease activity
DBK22_RS06075	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DBK22_RS06080	COG0328	RNA-DNA hybrid ribonuclease activity
DBK22_RS06090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBK22_RS06105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DBK22_RS06115	COG1755	Isoprenylcysteine carboxyl methyltransferase
DBK22_RS06120	COG3424	synthase
DBK22_RS06140	COG2323	membrane
DBK22_RS06145	COG1335	isochorismatase
DBK22_RS06155	COG2233	PERMEase
DBK22_RS06165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DBK22_RS06170	COG1199	ATP-dependent helicase activity
DBK22_RS06185	COG0116	Belongs to the methyltransferase superfamily
DBK22_RS06215	COG3359	exonuclease
DBK22_RS06220	COG1111	helicase
DBK22_RS06220	COG1205	dead DEAH box helicase
DBK22_RS06225	COG2190	(PTS) system
DBK22_RS06230	COG0071	Belongs to the small heat shock protein (HSP20) family
DBK22_RS06270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBK22_RS06270	COG4499	WXG100 protein secretion system (Wss), protein YukC
DBK22_RS06280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DBK22_RS06285	COG3935	DnaD domain protein
DBK22_RS06295	COG0436	Aminotransferase
DBK22_RS06300	COG5353	protein conserved in bacteria
DBK22_RS06310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBK22_RS06310	COG1199	ATP-dependent helicase activity
DBK22_RS06340	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS06345	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBK22_RS06360	COG1694	Mazg nucleotide pyrophosphohydrolase
DBK22_RS06365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS06370	COG2140	Oxalate decarboxylase
DBK22_RS06380	COG4347	Protein of unknown function (DUF1405)
DBK22_RS06385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DBK22_RS06385	COG2010	Cytochrome c
DBK22_RS06390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DBK22_RS06395	COG0723	plastoquinol--plastocyanin reductase activity
DBK22_RS06410	COG0457	Tetratricopeptide repeat
DBK22_RS06420	COG0287	Prephenate dehydrogenase
DBK22_RS06455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DBK22_RS06460	COG4401	Chorismate mutase type I
DBK22_RS06475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DBK22_RS06480	COG0105	UTP biosynthetic process
DBK22_RS06485	COG0142	geranyltranstransferase activity
DBK22_RS06495	COG0142	geranyltranstransferase activity
DBK22_RS06510	COG0776	regulation of translation
DBK22_RS06515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DBK22_RS06555	COG0539	negative regulation of cytoplasmic translation
DBK22_RS06570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DBK22_RS06575	COG2959	enzyme of heme biosynthesis
DBK22_RS06580	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS06580	COG3773	Cell wall hydrolase
DBK22_RS06585	COG2339	peptidase activity
DBK22_RS06590	COG0492	ferredoxin-NADP+ reductase activity
DBK22_RS06595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBK22_RS06600	COG4862	establishment of competence for transformation
DBK22_RS06605	COG1408	metallophosphoesterase
DBK22_RS06615	COG1388	LysM domain
DBK22_RS06620	COG1266	CAAX protease self-immunity
DBK22_RS06625	COG0514	ATP-dependent DNA helicase (RecQ)
DBK22_RS06630	COG4955	Helix-turn-helix domain
DBK22_RS06635	COG1141	Ferredoxin
DBK22_RS06640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DBK22_RS06645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBK22_RS06655	COG1595	DNA-templated transcription, initiation
DBK22_RS06660	COG5002	protein histidine kinase activity
DBK22_RS06665	COG0745	RESPONSE REGULATOR receiver
DBK22_RS06670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBK22_RS06675	COG1333	cytochrome c biogenesis protein
DBK22_RS06680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS06685	COG1187	pseudouridine synthase activity
DBK22_RS06690	COG0700	Nucleoside recognition
DBK22_RS06695	COG2715	membrane protein required for spore maturation
DBK22_RS06700	COG1686	Belongs to the peptidase S11 family
DBK22_RS06725	COG1547	Domain of unknown function (DUF309)
DBK22_RS06730	COG0456	acetyltransferase
DBK22_RS06745	COG0307	riboflavin synthase, alpha
DBK22_RS06750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBK22_RS06750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DBK22_RS06760	COG0681	Belongs to the peptidase S26 family
DBK22_RS06770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DBK22_RS06775	COG4086	secreted protein
DBK22_RS06780	COG0019	diaminopimelate decarboxylase activity
DBK22_RS06785	COG0697	spore germination
DBK22_RS06800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DBK22_RS06820	COG1191	sigma factor activity
DBK22_RS06830	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS06835	COG1686	Belongs to the peptidase S11 family
DBK22_RS06840	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DBK22_RS06845	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DBK22_RS06850	COG4974	Belongs to the 'phage' integrase family
DBK22_RS06860	COG0735	belongs to the Fur family
DBK22_RS06865	COG1300	Membrane
DBK22_RS06880	COG0281	malic enzyme
DBK22_RS06885	COG1757	Na H antiporter
DBK22_RS06890	COG1027	Aspartate ammonia-lyase
DBK22_RS06895	COG0252	asparaginase activity
DBK22_RS06900	COG1396	sequence-specific DNA binding
DBK22_RS06905	COG1379	DNA repair
DBK22_RS06910	COG0494	nUDIX hydrolase
DBK22_RS06920	COG0667	Aldo Keto reductase
DBK22_RS06930	COG1073	alpha beta
DBK22_RS06940	COG4918	Iron-sulphur cluster biosynthesis
DBK22_RS06945	COG0456	acetyltransferase
DBK22_RS06945	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DBK22_RS06950	COG2329	Antibiotic biosynthesis monooxygenase
DBK22_RS06955	COG0456	acetyltransferase
DBK22_RS06960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBK22_RS06975	COG0628	permease
DBK22_RS06985	COG0346	lactoylglutathione lyase activity
DBK22_RS06995	COG3048	D-serine ammonia-lyase activity
DBK22_RS07000	COG0300	oxidoreductase activity
DBK22_RS07005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS07010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBK22_RS07015	COG1024	Enoyl-CoA hydratase
DBK22_RS07020	COG3425	synthase
DBK22_RS07025	COG2124	cytochrome p450
DBK22_RS07030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS07030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS07030	COG3321	synthase
DBK22_RS07030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS07035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS07035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07035	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07035	COG3321	synthase
DBK22_RS07040	COG3321	synthase
DBK22_RS07040	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07040	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS07040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07040	COG0300	oxidoreductase activity
DBK22_RS07045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07045	COG0300	oxidoreductase activity
DBK22_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07045	COG3321	synthase
DBK22_RS07045	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS07050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS07050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS07050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07050	COG3321	synthase
DBK22_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07055	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS07055	COG0300	oxidoreductase activity
DBK22_RS07055	COG3321	synthase
DBK22_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07060	COG3321	synthase
DBK22_RS07060	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DBK22_RS07060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS07065	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS07070	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS07085	COG2070	2-Nitropropane dioxygenase
DBK22_RS07085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBK22_RS07110	COG0596	Alpha beta hydrolase
DBK22_RS07125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DBK22_RS07130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBK22_RS07145	COG0706	membrane insertase activity
DBK22_RS07150	COG2195	Cleaves the N-terminal amino acid of tripeptides
DBK22_RS07155	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBK22_RS07160	COG0346	lactoylglutathione lyase activity
DBK22_RS07170	COG1376	ErfK ybiS ycfS ynhG family protein
DBK22_RS07175	COG4129	membrane
DBK22_RS07180	COG1126	abc transporter atp-binding protein
DBK22_RS07185	COG0765	amino acid transport
DBK22_RS07190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS07200	COG1597	lipid kinase activity
DBK22_RS07205	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBK22_RS07210	COG0022	dehydrogenase e1 component
DBK22_RS07215	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DBK22_RS07220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBK22_RS07225	COG3426	butyrate kinase activity
DBK22_RS07230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBK22_RS07235	COG0280	phosphate acetyltransferase
DBK22_RS07240	COG3290	protein histidine kinase activity
DBK22_RS07240	COG3829	transcription factor binding
DBK22_RS07250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DBK22_RS07255	COG2079	MmgE PrpD family protein
DBK22_RS07260	COG0372	Belongs to the citrate synthase family
DBK22_RS07265	COG1960	acyl-CoA dehydrogenase activity
DBK22_RS07270	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBK22_RS07275	COG0183	Belongs to the thiolase family
DBK22_RS07280	COG0584	glycerophosphoryl diester phosphodiesterase
DBK22_RS07285	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS07305	COG1902	pentaerythritol trinitrate reductase activity
DBK22_RS07320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBK22_RS07325	COG0745	RESPONSE REGULATOR receiver
DBK22_RS07330	COG0750	zinc metalloprotease
DBK22_RS07335	COG0497	DNA recombination
DBK22_RS07345	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DBK22_RS07355	COG0142	geranyltranstransferase activity
DBK22_RS07365	COG1570	exodeoxyribonuclease VII activity
DBK22_RS07380	COG1302	Protein conserved in bacteria
DBK22_RS07385	COG0439	Biotin carboxylase
DBK22_RS07390	COG0511	ligase activity, forming carbon-carbon bonds
DBK22_RS07430	COG3854	ATPases associated with a variety of cellular activities
DBK22_RS07445	COG0006	proline dipeptidase activity
DBK22_RS07455	COG3872	metal-dependent enzyme
DBK22_RS07465	COG1752	Esterase of the alpha-beta hydrolase superfamily
DBK22_RS07480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBK22_RS07500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBK22_RS07515	COG1396	sequence-specific DNA binding
DBK22_RS07525	COG0681	Belongs to the peptidase S26 family
DBK22_RS07550	COG4940	Competence protein ComGF
DBK22_RS07560	COG4970	Tfp pilus assembly protein FimT
DBK22_RS07565	COG4537	Required for transformation and DNA binding
DBK22_RS07570	COG1459	type II secretion system
DBK22_RS07575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DBK22_RS07580	COG0598	Magnesium transport protein CorA
DBK22_RS07585	COG1253	flavin adenine dinucleotide binding
DBK22_RS07590	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS07600	COG1393	Belongs to the ArsC family
DBK22_RS07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS07620	COG0011	TIGRFAM Protein of
DBK22_RS07630	COG2866	Carboxypeptidase
DBK22_RS07635	COG1940	carbohydrate kinase activity
DBK22_RS07640	COG4483	Protein conserved in bacteria
DBK22_RS07645	COG1757	Na H antiporter
DBK22_RS07655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DBK22_RS07660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DBK22_RS07670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBK22_RS07675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBK22_RS07680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBK22_RS07685	COG0581	inorganic phosphate transmembrane transporter activity
DBK22_RS07690	COG0573	inorganic phosphate transmembrane transporter activity
DBK22_RS07695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DBK22_RS07705	COG0477	Major facilitator Superfamily
DBK22_RS07710	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DBK22_RS07715	COG2839	Protein conserved in bacteria
DBK22_RS07720	COG5521	maltodextrose utilization protein MalA
DBK22_RS07725	COG1388	LysM domain
DBK22_RS07735	COG4709	membrane
DBK22_RS07740	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DBK22_RS07745	COG0735	belongs to the Fur family
DBK22_RS07750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS07765	COG0513	Belongs to the DEAD box helicase family
DBK22_RS07780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBK22_RS07785	COG2384	SAM-dependent methyltransferase
DBK22_RS07790	COG2010	Cytochrome c
DBK22_RS07795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBK22_RS07800	COG0358	DNA primase activity
DBK22_RS07815	COG0517	IMP dehydrogenase activity
DBK22_RS07820	COG0751	glycine-tRNA ligase activity
DBK22_RS07840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBK22_RS07845	COG0295	cytidine deaminase activity
DBK22_RS07850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DBK22_RS07860	COG1480	7TM receptor with intracellular HD hydrolase
DBK22_RS07865	COG1702	phosphate starvation-inducible protein PhoH
DBK22_RS07870	COG0561	phosphatase activity
DBK22_RS07885	COG4864	UPF0365 protein
DBK22_RS07890	COG1030	water channel activity
DBK22_RS07895	COG1610	YqeY-like protein
DBK22_RS07900	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DBK22_RS07905	COG1283	sodium-dependent phosphate transmembrane transporter activity
DBK22_RS07910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DBK22_RS07915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DBK22_RS07945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DBK22_RS07960	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS07975	COG1466	dna polymerase III delta subunit
DBK22_RS07990	COG2333	competence protein COMEC
DBK22_RS07990	COG0658	competence protein
DBK22_RS07995	COG2131	deaminase
DBK22_RS08000	COG1596	polysaccharide export
DBK22_RS08000	COG1555	photosystem II stabilization
DBK22_RS08005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBK22_RS08010	COG2226	methyltransferase
DBK22_RS08015	COG0799	negative regulation of ribosome biogenesis
DBK22_RS08020	COG1713	HD superfamily hydrolase involved in NAD metabolism
DBK22_RS08030	COG1534	Rna-binding protein
DBK22_RS08035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBK22_RS08040	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DBK22_RS08045	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DBK22_RS08055	COG2755	lipolytic protein G-D-S-L family
DBK22_RS08060	COG0726	polysaccharide deacetylase
DBK22_RS08065	COG0398	Pfam SNARE associated Golgi protein
DBK22_RS08095	COG3708	Transcriptional regulator
DBK22_RS08095	COG2207	Transcriptional regulator
DBK22_RS08105	COG0563	adenylate kinase activity
DBK22_RS08120	COG0456	acetyltransferase
DBK22_RS08125	COG2318	DinB family
DBK22_RS08135	COG0561	phosphatase activity
DBK22_RS08140	COG0561	phosphatase activity
DBK22_RS08150	COG1482	cell wall glycoprotein biosynthetic process
DBK22_RS08155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBK22_RS08155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DBK22_RS08155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS08160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS08160	COG3711	transcriptional antiterminator
DBK22_RS08170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBK22_RS08175	COG0583	DNA-binding transcription factor activity
DBK22_RS08180	COG2814	Major facilitator Superfamily
DBK22_RS08185	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DBK22_RS08185	COG2124	cytochrome p450
DBK22_RS08190	COG1309	transcriptional regulator
DBK22_RS08195	COG2226	methyltransferase
DBK22_RS08205	COG2116	formate transmembrane transporter activity
DBK22_RS08210	COG5609	conserved protein (DUF2294)
DBK22_RS08215	COG3383	formate dehydrogenase (NAD+) activity
DBK22_RS08220	COG2427	Protein of unknown function (DUF1641)
DBK22_RS08230	COG0626	cystathionine gamma-synthase activity
DBK22_RS08235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DBK22_RS08260	COG0768	penicillin binding
DBK22_RS08290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DBK22_RS08315	COG0628	permease
DBK22_RS08320	COG1126	abc transporter atp-binding protein
DBK22_RS08325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS08330	COG0765	amino acid transport
DBK22_RS08335	COG0765	amino acid transport
DBK22_RS08350	COG3881	PFAM PRC-barrel domain
DBK22_RS08355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DBK22_RS08360	COG0457	Tetratricopeptide repeat
DBK22_RS08370	COG1104	cysteine desulfurase activity
DBK22_RS08375	COG1959	2 iron, 2 sulfur cluster binding
DBK22_RS08380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DBK22_RS08385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DBK22_RS08410	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS08410	COG4991	sh3 domain protein
DBK22_RS08410	COG3103	Sh3 type 3 domain protein
DBK22_RS08420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBK22_RS08430	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DBK22_RS08430	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DBK22_RS08435	COG5416	Lipopolysaccharide assembly protein A domain
DBK22_RS08440	COG0490	domain, Protein
DBK22_RS08445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBK22_RS08445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBK22_RS08455	COG2244	polysaccharide biosynthetic process
DBK22_RS08460	COG2323	membrane
DBK22_RS08470	COG1862	Preprotein translocase
DBK22_RS08515	COG1388	LysM domain
DBK22_RS08525	COG0157	Belongs to the NadC ModD family
DBK22_RS08530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DBK22_RS08535	COG1104	cysteine desulfurase activity
DBK22_RS08540	COG1827	regulation of RNA biosynthetic process
DBK22_RS08545	COG0077	Prephenate dehydratase
DBK22_RS08560	COG3290	protein histidine kinase activity
DBK22_RS08565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DBK22_RS08570	COG2868	ribosomal protein
DBK22_RS08580	COG1994	Peptidase M50
DBK22_RS08585	COG0739	heme binding
DBK22_RS08590	COG2894	cell division
DBK22_RS08600	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DBK22_RS08605	COG1792	Involved in formation and maintenance of cell shape
DBK22_RS08610	COG1077	Cell shape determining protein MreB Mrl
DBK22_RS08630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DBK22_RS08635	COG0285	dihydrofolate synthase activity
DBK22_RS08640	COG0525	valine-tRNA ligase activity
DBK22_RS08650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DBK22_RS08655	COG1388	LysM domain
DBK22_RS08665	COG0113	porphobilinogen synthase activity
DBK22_RS08670	COG1587	Uroporphyrinogen-III synthase
DBK22_RS08680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DBK22_RS08700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DBK22_RS08705	COG0470	DNA polymerase III
DBK22_RS08705	COG1067	ATP-dependent peptidase activity
DBK22_RS08720	COG0457	Tetratricopeptide repeat
DBK22_RS08720	COG1477	protein flavinylation
DBK22_RS08735	COG0473	3-isopropylmalate dehydrogenase activity
DBK22_RS08750	COG0440	acetolactate synthase activity
DBK22_RS08755	COG0028	Belongs to the TPP enzyme family
DBK22_RS08780	COG0622	Phosphoesterase
DBK22_RS08785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBK22_RS08795	COG5401	PFAM Sporulation and spore germination
DBK22_RS08805	COG1846	Transcriptional regulator
DBK22_RS08810	COG2197	response regulator
DBK22_RS08815	COG0824	Thioesterase
DBK22_RS08820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBK22_RS08825	COG1053	succinate dehydrogenase
DBK22_RS08830	COG2009	succinate dehydrogenase
DBK22_RS08835	COG1719	4-vinyl reductase, 4VR
DBK22_RS08840	COG0527	aspartate kinase activity
DBK22_RS08850	COG3118	belongs to the thioredoxin family
DBK22_RS08855	COG3534	alpha-L-arabinofuranosidase
DBK22_RS08860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DBK22_RS08865	COG2086	electron transfer activity
DBK22_RS08870	COG1024	Enoyl-CoA hydratase
DBK22_RS08875	COG1309	transcriptional regulator
DBK22_RS08880	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS08890	COG3766	membrane
DBK22_RS08900	COG1796	DNA polymerase
DBK22_RS08900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DBK22_RS08905	COG1286	toxin biosynthetic process
DBK22_RS08920	COG0072	phenylalanine-tRNA ligase activity
DBK22_RS08920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBK22_RS08925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DBK22_RS08930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBK22_RS08940	COG3835	regulator
DBK22_RS08945	COG0277	FAD linked oxidase domain protein
DBK22_RS08950	COG0247	lactate metabolic process
DBK22_RS08955	COG1966	Carbon starvation protein
DBK22_RS08960	COG3534	alpha-L-arabinofuranosidase
DBK22_RS08965	COG0395	ABC-type sugar transport system, permease component
DBK22_RS08970	COG1175	transmembrane transport
DBK22_RS08975	COG1653	transport
DBK22_RS08985	COG0647	UMP catabolic process
DBK22_RS08990	COG0235	Class ii aldolase
DBK22_RS08995	COG1069	ribulokinase activity
DBK22_RS09000	COG2160	L-arabinose isomerase activity
DBK22_RS09005	COG3507	Belongs to the glycosyl hydrolase 43 family
DBK22_RS09010	COG1363	Peptidase, m42
DBK22_RS09020	COG3326	Membrane
DBK22_RS09035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DBK22_RS09040	COG1346	cytolysis
DBK22_RS09045	COG1380	Effector of murein hydrolase LrgA
DBK22_RS09050	COG3279	Response regulator of the LytR AlgR family
DBK22_RS09055	COG3275	phosphorelay sensor kinase activity
DBK22_RS09075	COG0398	Pfam SNARE associated Golgi protein
DBK22_RS09080	COG1484	DNA-dependent DNA replication
DBK22_RS09085	COG3611	Membrane attachment protein
DBK22_RS09100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBK22_RS09105	COG1733	regulation of RNA biosynthetic process
DBK22_RS09110	COG2814	Major facilitator Superfamily
DBK22_RS09115	COG0656	L-ascorbic acid biosynthetic process
DBK22_RS09120	COG0237	dephospho-CoA kinase activity
DBK22_RS09125	COG1971	Probably functions as a manganese efflux pump
DBK22_RS09130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DBK22_RS09135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBK22_RS09135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBK22_RS09140	COG5002	protein histidine kinase activity
DBK22_RS09145	COG0745	RESPONSE REGULATOR receiver
DBK22_RS09155	COG0538	isocitrate dehydrogenase activity
DBK22_RS09160	COG0372	Belongs to the citrate synthase family
DBK22_RS09180	COG0628	permease
DBK22_RS09185	COG3030	protein affecting phage T7 exclusion by the F plasmid
DBK22_RS09190	COG0469	pyruvate kinase activity
DBK22_RS09210	COG0281	malic enzyme
DBK22_RS09215	COG0587	DNA-directed DNA polymerase activity
DBK22_RS09235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DBK22_RS09245	COG4109	DRTGG domain
DBK22_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS09270	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBK22_RS09280	COG0827	DNA restriction-modification system
DBK22_RS09285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DBK22_RS09290	COG3874	Sporulation protein YtfJ
DBK22_RS09300	COG1714	RDD family
DBK22_RS09305	COG0616	signal peptide processing
DBK22_RS09310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBK22_RS09315	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DBK22_RS09320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBK22_RS09335	COG1104	cysteine desulfurase activity
DBK22_RS09340	COG1114	Component of the transport system for branched-chain amino acids
DBK22_RS09350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DBK22_RS09355	COG1309	transcriptional regulator
DBK22_RS09360	COG1956	GAF domain-containing protein
DBK22_RS09365	COG2203	Gaf domain
DBK22_RS09365	COG2199	diguanylate cyclase activity
DBK22_RS09380	COG0457	Tetratricopeptide repeat
DBK22_RS09395	COG0582	viral genome integration into host DNA
DBK22_RS09400	COG1017	nitric oxide dioxygenase activity
DBK22_RS09400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBK22_RS09415	COG0693	protein deglycase activity
DBK22_RS09430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBK22_RS09435	COG1378	Sugar-specific transcriptional regulator TrmB
DBK22_RS09455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DBK22_RS09460	COG0454	-acetyltransferase
DBK22_RS09465	COG0517	IMP dehydrogenase activity
DBK22_RS09470	COG0123	including yeast histone deacetylase and acetoin utilization protein
DBK22_RS09475	COG1360	Flagellar Motor Protein
DBK22_RS09480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DBK22_RS09485	COG1609	Transcriptional regulator
DBK22_RS09490	COG1605	Chorismate mutase
DBK22_RS09490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DBK22_RS09495	COG3118	belongs to the thioredoxin family
DBK22_RS09500	COG4980	gas vesicle protein
DBK22_RS09505	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DBK22_RS09515	COG1674	ftsk spoiiie
DBK22_RS09520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBK22_RS09530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS09540	COG1363	Peptidase, m42
DBK22_RS09545	COG5584	Small secreted protein
DBK22_RS09550	COG0281	malic enzyme
DBK22_RS09555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS09570	COG0510	thiamine kinase activity
DBK22_RS09575	COG1597	lipid kinase activity
DBK22_RS09585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DBK22_RS09590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DBK22_RS09595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBK22_RS09600	COG2252	PERMEase
DBK22_RS09605	COG4473	ABC transporter
DBK22_RS09610	COG1131	(ABC) transporter
DBK22_RS09615	COG1349	DNA-binding transcription factor activity
DBK22_RS09620	COG1187	pseudouridine synthase activity
DBK22_RS09625	COG2244	polysaccharide biosynthetic process
DBK22_RS09630	COG2081	HI0933 family
DBK22_RS09635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBK22_RS09665	COG1486	melibiose metabolic process
DBK22_RS09675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBK22_RS09690	COG2202	Pas domain
DBK22_RS09690	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS09695	COG2814	Major facilitator Superfamily
DBK22_RS09700	COG5522	Integral membrane protein (intg_mem_TP0381)
DBK22_RS09705	COG0577	efflux transmembrane transporter activity
DBK22_RS09710	COG1136	(ABC) transporter
DBK22_RS09715	COG2205	protein histidine kinase activity
DBK22_RS09720	COG0745	RESPONSE REGULATOR receiver
DBK22_RS09725	COG0577	efflux transmembrane transporter activity
DBK22_RS09730	COG1136	(ABC) transporter
DBK22_RS09750	COG1131	(ABC) transporter
DBK22_RS09755	COG1725	Transcriptional regulator
DBK22_RS09765	COG1242	4 iron, 4 sulfur cluster binding
DBK22_RS09770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DBK22_RS09780	COG0584	glycerophosphoryl diester phosphodiesterase
DBK22_RS09790	COG2267	carboxylic ester hydrolase activity
DBK22_RS09795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DBK22_RS09800	COG1113	amino acid transport
DBK22_RS09805	COG0367	asparagine synthase
DBK22_RS09825	COG1506	peptidase
DBK22_RS09830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBK22_RS09835	COG1116	anion transmembrane transporter activity
DBK22_RS09840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBK22_RS09845	COG0494	nUDIX hydrolase
DBK22_RS09850	COG4824	toxin secretion phage lysis holin
DBK22_RS09855	COG0783	Belongs to the Dps family
DBK22_RS09880	COG0288	reversible hydration of carbon dioxide
DBK22_RS09890	COG1271	oxidase subunit
DBK22_RS09895	COG1294	oxidase, subunit
DBK22_RS09905	COG4948	Mandelate Racemase Muconate Lactonizing
DBK22_RS09915	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DBK22_RS09920	COG0596	Alpha beta hydrolase
DBK22_RS09930	COG1169	isochorismate synthase
DBK22_RS09935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DBK22_RS09940	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
DBK22_RS10065	COG3859	Proton-coupled thiamine transporter YuaJ
DBK22_RS10070	COG2268	Band 7 protein
DBK22_RS10075	COG1585	Membrane protein implicated in regulation of membrane protease activity
DBK22_RS10080	COG2318	DinB family
DBK22_RS10090	COG1454	alcohol dehydrogenase
DBK22_RS10100	COG1510	regulation of RNA biosynthetic process
DBK22_RS10115	COG0569	domain protein
DBK22_RS10120	COG1705	Flagellar rod assembly protein muramidase FlgJ
DBK22_RS10125	COG1017	nitric oxide dioxygenase activity
DBK22_RS10125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DBK22_RS10150	COG0628	permease
DBK22_RS10155	COG0673	inositol 2-dehydrogenase activity
DBK22_RS10160	COG0693	protein deglycase activity
DBK22_RS10165	COG0840	transmembrane signaling receptor activity
DBK22_RS10170	COG0840	transmembrane signaling receptor activity
DBK22_RS10175	COG0840	transmembrane signaling receptor activity
DBK22_RS10180	COG0840	transmembrane signaling receptor activity
DBK22_RS10195	COG2070	2-Nitropropane dioxygenase
DBK22_RS10200	COG0432	Pfam Uncharacterised protein family UPF0047
DBK22_RS10205	COG0366	Alpha amylase catalytic
DBK22_RS10210	COG1253	flavin adenine dinucleotide binding
DBK22_RS10215	COG2738	Putative neutral zinc metallopeptidase
DBK22_RS10230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DBK22_RS10255	COG1335	isochorismatase
DBK22_RS10260	COG1979	alcohol dehydrogenase
DBK22_RS10265	COG1979	alcohol dehydrogenase
DBK22_RS10270	COG2155	Conserved Protein
DBK22_RS10275	COG1098	S1 RNA binding domain
DBK22_RS10280	COG0436	Aminotransferase
DBK22_RS10285	COG1522	sequence-specific DNA binding
DBK22_RS10290	COG2267	carboxylic ester hydrolase activity
DBK22_RS10300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DBK22_RS10305	COG2205	protein histidine kinase activity
DBK22_RS10315	COG5018	Exonuclease
DBK22_RS10320	COG2814	Major facilitator Superfamily
DBK22_RS10325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBK22_RS10330	COG3011	Protein conserved in bacteria
DBK22_RS10340	COG3290	protein histidine kinase activity
DBK22_RS10345	COG4565	transcriptional regulatory protein
DBK22_RS10375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBK22_RS10375	COG2111	Na H antiporter
DBK22_RS10380	COG2111	Na H antiporter
DBK22_RS10385	COG1006	Multisubunit Na H antiporter MnhC subunit
DBK22_RS10390	COG0651	ATP synthesis coupled electron transport
DBK22_RS10395	COG1863	multisubunit Na H antiporter MnhE subunit
DBK22_RS10400	COG2212	antiporter activity
DBK22_RS10405	COG1320	monovalent cation:proton antiporter activity
DBK22_RS10410	COG2050	protein possibly involved in aromatic compounds catabolism
DBK22_RS10415	COG2197	response regulator
DBK22_RS10420	COG4585	Histidine kinase
DBK22_RS10430	COG0142	geranyltranstransferase activity
DBK22_RS10445	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DBK22_RS10450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DBK22_RS10455	COG1335	isochorismatase
DBK22_RS10460	COG5506	Protein of unknown function (DUF1694)
DBK22_RS10475	COG0628	permease
DBK22_RS10485	COG1418	mRNA catabolic process
DBK22_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS10500	COG1511	domain protein
DBK22_RS10505	COG1674	ftsk spoiiie
DBK22_RS10505	COG0433	COG0433 Predicted ATPase
DBK22_RS10510	COG4499	WXG100 protein secretion system (Wss), protein YukC
DBK22_RS10515	COG5417	Belongs to the EsaB family
DBK22_RS10520	COG4842	Belongs to the WXG100 family
DBK22_RS10525	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DBK22_RS10525	COG2508	Transcriptional regulator
DBK22_RS10530	COG0686	Belongs to the AlaDH PNT family
DBK22_RS10535	COG5634	Uncharacterized conserved protein (DUF2278)
DBK22_RS10540	COG3251	PFAM MbtH domain protein
DBK22_RS10545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS10550	COG3433	isochorismatase activity
DBK22_RS10550	COG1535	isochorismatase
DBK22_RS10555	COG1021	2,3-dihydroxybenzoate-AMP ligase
DBK22_RS10560	COG1169	isochorismate synthase
DBK22_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS10570	COG2819	hydrolase of the alpha beta superfamily
DBK22_RS10575	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DBK22_RS10580	COG1268	BioY protein
DBK22_RS10585	COG2056	Na+-H+ antiporter family
DBK22_RS10595	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DBK22_RS10605	COG3584	3D domain protein
DBK22_RS10620	COG1252	NADH dehydrogenase
DBK22_RS10645	COG1131	(ABC) transporter
DBK22_RS10670	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
DBK22_RS10675	COG0316	Belongs to the HesB IscA family
DBK22_RS10685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBK22_RS10695	COG1252	NADH dehydrogenase
DBK22_RS10700	COG4837	Protein of unknown function (DUF1462)
DBK22_RS10705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DBK22_RS10710	COG0823	Involved in the tonB-independent uptake of proteins
DBK22_RS10710	COG1506	peptidase
DBK22_RS10710	COG4946	Tricorn protease homolog
DBK22_RS10720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DBK22_RS10725	COG0460	homoserine dehydrogenase
DBK22_RS10730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DBK22_RS10735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DBK22_RS10740	COG0647	UMP catabolic process
DBK22_RS10745	COG2445	Protein of unknown function DUF86
DBK22_RS10750	COG4470	Protein conserved in bacteria
DBK22_RS10760	COG0739	heme binding
DBK22_RS10770	COG0737	Belongs to the 5'-nucleotidase family
DBK22_RS10775	COG0730	response to heat
DBK22_RS10780	COG1801	Protein of unknown function DUF72
DBK22_RS10795	COG2508	Transcriptional regulator
DBK22_RS10800	COG0457	Tetratricopeptide repeat
DBK22_RS10810	COG2814	Major facilitator Superfamily
DBK22_RS10815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DBK22_RS10820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBK22_RS10825	COG2356	endonuclease I
DBK22_RS10830	COG3842	ATPase activity
DBK22_RS10835	COG2188	Transcriptional regulator
DBK22_RS10840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBK22_RS10845	COG0395	ABC-type sugar transport system, permease component
DBK22_RS10850	COG1175	transmembrane transport
DBK22_RS10855	COG1653	transport
DBK22_RS10860	COG2222	sugar isomerase
DBK22_RS10865	COG0789	Transcriptional regulator
DBK22_RS10880	COG0322	excinuclease ABC activity
DBK22_RS10885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DBK22_RS10890	COG2226	methyltransferase
DBK22_RS10900	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS10905	COG0719	Fe-S assembly protein
DBK22_RS10910	COG0822	iron-sulfur transferase activity
DBK22_RS10915	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBK22_RS10920	COG0719	Fe-S assembly protein
DBK22_RS10925	COG0396	ATPase activity
DBK22_RS10935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBK22_RS10940	COG1464	Belongs to the NlpA lipoprotein family
DBK22_RS10945	COG2011	ABC-type metal ion transport system permease component
DBK22_RS10950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DBK22_RS10960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS10965	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DBK22_RS10980	COG1393	Belongs to the ArsC family
DBK22_RS10985	COG1960	acyl-CoA dehydrogenase activity
DBK22_RS10990	COG0183	Belongs to the thiolase family
DBK22_RS10995	COG1250	3-hydroxyacyl-CoA dehydrogenase
DBK22_RS10995	COG1024	Enoyl-CoA hydratase
DBK22_RS11010	COG0477	Major facilitator Superfamily
DBK22_RS11020	COG5577	PFAM Coat F domain
DBK22_RS11025	COG1846	Transcriptional regulator
DBK22_RS11030	COG0477	Major facilitator Superfamily
DBK22_RS11035	COG1942	4-Oxalocrotonate Tautomerase
DBK22_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS11045	COG0583	DNA-binding transcription factor activity
DBK22_RS11055	COG0583	DNA-binding transcription factor activity
DBK22_RS11075	COG1120	ATPase activity
DBK22_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS11095	COG0783	Belongs to the Dps family
DBK22_RS11100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBK22_RS11105	COG0745	RESPONSE REGULATOR receiver
DBK22_RS11110	COG2205	protein histidine kinase activity
DBK22_RS11110	COG2770	Histidine kinase
DBK22_RS11120	COG1309	transcriptional regulator
DBK22_RS11125	COG0114	fumarate hydratase activity
DBK22_RS11135	COG0697	spore germination
DBK22_RS11140	COG0814	amino acid
DBK22_RS11150	COG2197	response regulator
DBK22_RS11155	COG4585	Histidine kinase
DBK22_RS11160	COG4758	membrane
DBK22_RS11165	COG3595	metallopeptidase activity
DBK22_RS11170	COG1842	Phage shock protein A
DBK22_RS11175	COG4758	membrane
DBK22_RS11180	COG2814	Major facilitator Superfamily
DBK22_RS11185	COG2096	Adenosyltransferase
DBK22_RS11190	COG1120	ATPase activity
DBK22_RS11195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS11200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBK22_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS11210	COG3386	PFAM SMP-30 Gluconolaconase
DBK22_RS11215	COG2205	protein histidine kinase activity
DBK22_RS11220	COG0745	RESPONSE REGULATOR receiver
DBK22_RS11230	COG1191	sigma factor activity
DBK22_RS11240	COG2140	Oxalate decarboxylase
DBK22_RS11250	COG1120	ATPase activity
DBK22_RS11255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS11260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS11265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBK22_RS11270	COG0531	amino acid
DBK22_RS11280	COG1988	membrane-bound metal-dependent
DBK22_RS11285	COG1368	sulfuric ester hydrolase activity
DBK22_RS11290	COG1910	domain protein
DBK22_RS11295	COG0725	ABC transporter, periplasmic molybdate-binding protein
DBK22_RS11300	COG4149	molybdate abc transporter
DBK22_RS11305	COG2197	response regulator
DBK22_RS11310	COG3850	Histidine kinase
DBK22_RS11315	COG1131	(ABC) transporter
DBK22_RS11325	COG0842	Transport permease protein
DBK22_RS11330	COG0656	L-ascorbic acid biosynthetic process
DBK22_RS11350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DBK22_RS11355	COG3973	AAA domain
DBK22_RS11360	COG2860	membrane
DBK22_RS11370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DBK22_RS11375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DBK22_RS11380	COG2217	Heavy metal translocating P-type atpase
DBK22_RS11385	COG2217	Heavy metal translocating P-type atpase
DBK22_RS11390	COG2608	mercury ion transmembrane transporter activity
DBK22_RS11395	COG1937	Protein conserved in bacteria
DBK22_RS11400	COG0673	inositol 2-dehydrogenase activity
DBK22_RS11415	COG2814	Major facilitator Superfamily
DBK22_RS11435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBK22_RS11440	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DBK22_RS11445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBK22_RS11450	COG1126	abc transporter atp-binding protein
DBK22_RS11455	COG0765	amino acid transport
DBK22_RS11460	COG0765	amino acid transport
DBK22_RS11465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS11470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS11475	COG0454	-acetyltransferase
DBK22_RS11480	COG0583	DNA-binding transcription factor activity
DBK22_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS11490	COG2732	(Barnase) inhibitor
DBK22_RS11505	COG0557	exoribonuclease II activity
DBK22_RS11510	COG1647	Serine aminopeptidase, S33
DBK22_RS11515	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBK22_RS11520	COG1476	TRANSCRIPTIONal
DBK22_RS11525	COG1396	sequence-specific DNA binding
DBK22_RS11530	COG1396	sequence-specific DNA binding
DBK22_RS11535	COG1733	regulation of RNA biosynthetic process
DBK22_RS11565	COG1174	glycine betaine transport
DBK22_RS11570	COG1732	Glycine betaine
DBK22_RS11575	COG1174	glycine betaine transport
DBK22_RS11580	COG1125	glycine betaine transport
DBK22_RS11580	COG0517	IMP dehydrogenase activity
DBK22_RS11585	COG1510	regulation of RNA biosynthetic process
DBK22_RS11590	COG1174	glycine betaine transport
DBK22_RS11595	COG1732	Glycine betaine
DBK22_RS11600	COG1174	glycine betaine transport
DBK22_RS11605	COG0517	IMP dehydrogenase activity
DBK22_RS11605	COG1125	glycine betaine transport
DBK22_RS11610	COG1510	regulation of RNA biosynthetic process
DBK22_RS11615	COG2095	MarC family integral membrane protein
DBK22_RS11620	COG3064	Membrane
DBK22_RS11625	COG4640	response to antibiotic
DBK22_RS11630	COG0456	acetyltransferase
DBK22_RS11645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBK22_RS11660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBK22_RS11665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS11670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBK22_RS11680	COG2234	aminopeptidase activity
DBK22_RS11700	COG0126	phosphoglycerate kinase activity
DBK22_RS11705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBK22_RS11710	COG2390	Transcriptional regulator
DBK22_RS11715	COG2814	Major facilitator Superfamily
DBK22_RS11720	COG1609	Transcriptional regulator
DBK22_RS11725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBK22_RS11735	COG0583	DNA-binding transcription factor activity
DBK22_RS11740	COG0697	spore germination
DBK22_RS11745	COG1113	amino acid transport
DBK22_RS11755	COG1609	Transcriptional regulator
DBK22_RS11765	COG0561	phosphatase activity
DBK22_RS11775	COG1737	Transcriptional regulator
DBK22_RS11780	COG1070	Carbohydrate kinase
DBK22_RS11805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS11810	COG2186	Transcriptional regulator
DBK22_RS11815	COG1620	l-lactate permease
DBK22_RS11820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DBK22_RS11830	COG5039	Polysaccharide pyruvyl transferase
DBK22_RS11835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBK22_RS11840	COG0110	maltose O-acetyltransferase activity
DBK22_RS11845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DBK22_RS11850	COG2244	polysaccharide biosynthetic process
DBK22_RS11855	COG1216	Glycosyl transferase, family 2
DBK22_RS11860	COG5039	Polysaccharide pyruvyl transferase
DBK22_RS11865	COG1216	Glycosyl transferase, family 2
DBK22_RS11875	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS11880	COG1215	transferase activity, transferring glycosyl groups
DBK22_RS11885	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS11890	COG1086	Polysaccharide biosynthesis protein
DBK22_RS11895	COG0489	protein tyrosine kinase activity
DBK22_RS11900	COG3944	biosynthesis protein
DBK22_RS11905	COG1396	sequence-specific DNA binding
DBK22_RS11910	COG2272	Belongs to the type-B carboxylesterase lipase family
DBK22_RS11925	COG2364	Membrane
DBK22_RS11930	COG0456	acetyltransferase
DBK22_RS11935	COG3479	Phenolic acid decarboxylase
DBK22_RS11975	COG1357	PFAM Pentapeptide repeats (8 copies)
DBK22_RS11995	COG2223	nitrite transmembrane transporter activity
DBK22_RS12000	COG1609	Transcriptional regulator
DBK22_RS12010	COG0583	DNA-binding transcription factor activity
DBK22_RS12015	COG2828	Protein conserved in bacteria
DBK22_RS12020	COG0477	Major facilitator Superfamily
DBK22_RS12020	COG2814	Major facilitator Superfamily
DBK22_RS12025	COG1611	Belongs to the LOG family
DBK22_RS12030	COG1694	Mazg nucleotide pyrophosphohydrolase
DBK22_RS12035	COG0659	secondary active sulfate transmembrane transporter activity
DBK22_RS12040	COG0288	reversible hydration of carbon dioxide
DBK22_RS12045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DBK22_RS12050	COG4290	ribonuclease
DBK22_RS12055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DBK22_RS12060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS12070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DBK22_RS12080	COG1051	belongs to the nudix hydrolase family
DBK22_RS12085	COG0492	ferredoxin-NADP+ reductase activity
DBK22_RS12090	COG3883	PFAM NLP P60 protein
DBK22_RS12090	COG0791	NLP P60 protein
DBK22_RS12095	COG0457	Tetratricopeptide repeat
DBK22_RS12100	COG5002	protein histidine kinase activity
DBK22_RS12105	COG0745	RESPONSE REGULATOR receiver
DBK22_RS12110	COG1132	(ABC) transporter
DBK22_RS12115	COG0140	phosphoribosyl-ATP diphosphatase activity
DBK22_RS12115	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DBK22_RS12140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DBK22_RS12155	COG4990	cell redox homeostasis
DBK22_RS12160	COG0110	maltose O-acetyltransferase activity
DBK22_RS12180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DBK22_RS12195	COG1309	transcriptional regulator
DBK22_RS12200	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DBK22_RS12205	COG1950	PFAM Membrane protein of
DBK22_RS12210	COG1983	PspC domain protein
DBK22_RS12215	COG3595	metallopeptidase activity
DBK22_RS12230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DBK22_RS12240	COG4897	Protein conserved in bacteria
DBK22_RS12245	COG3848	Pyruvate phosphate dikinase
DBK22_RS12245	COG0574	Belongs to the PEP-utilizing enzyme family
DBK22_RS12250	COG1309	transcriptional regulator
DBK22_RS12255	COG2814	Major facilitator Superfamily
DBK22_RS12270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBK22_RS12280	COG0793	Belongs to the peptidase S41A family
DBK22_RS12280	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS12285	COG3420	alginic acid biosynthetic process
DBK22_RS12290	COG2177	Part of the ABC transporter FtsEX involved in
DBK22_RS12295	COG2884	Cell division ATP-binding protein ftsE
DBK22_RS12300	COG2010	Cytochrome c
DBK22_RS12305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS12320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBK22_RS12335	COG1516	flagellar protein fliS
DBK22_RS12340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DBK22_RS12345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBK22_RS12365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DBK22_RS12370	COG1256	bacterial-type flagellum assembly
DBK22_RS12370	COG4786	Flagellar basal body rod
DBK22_RS12375	COG3418	PFAM FlgN family protein
DBK22_RS12380	COG2747	anti-sigma28 factor FlgM
DBK22_RS12390	COG1040	competence protein
DBK22_RS12400	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DBK22_RS12405	COG1307	EDD domain protein, DegV family
DBK22_RS12410	COG2197	response regulator
DBK22_RS12415	COG4585	Histidine kinase
DBK22_RS12420	COG1739	Uncharacterized protein family UPF0029
DBK22_RS12425	COG1316	TRANSCRIPTIONal
DBK22_RS12430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBK22_RS12435	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS12440	COG1215	transferase activity, transferring glycosyl groups
DBK22_RS12445	COG3206	protein involved in exopolysaccharide biosynthesis
DBK22_RS12450	COG3307	-O-antigen
DBK22_RS12455	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DBK22_RS12460	COG0297	glycogen (starch) synthase activity
DBK22_RS12460	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS12465	COG2244	polysaccharide biosynthetic process
DBK22_RS12475	COG2247	cell wall binding repeat
DBK22_RS12475	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS12480	COG2385	sporulation resulting in formation of a cellular spore
DBK22_RS12480	COG2247	cell wall binding repeat
DBK22_RS12490	COG1316	TRANSCRIPTIONal
DBK22_RS12495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DBK22_RS12500	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DBK22_RS12505	COG1134	teichoic acid transport
DBK22_RS12510	COG1682	transport, permease protein
DBK22_RS12515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DBK22_RS12520	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS12525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DBK22_RS12530	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DBK22_RS12535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DBK22_RS12540	COG4193	domain, Protein
DBK22_RS12545	COG1482	cell wall glycoprotein biosynthetic process
DBK22_RS12550	COG0697	spore germination
DBK22_RS12555	COG0814	amino acid
DBK22_RS12565	COG1215	transferase activity, transferring glycosyl groups
DBK22_RS12570	COG2814	Major facilitator Superfamily
DBK22_RS12575	COG1316	TRANSCRIPTIONal
DBK22_RS12580	COG0561	phosphatase activity
DBK22_RS12585	COG2433	Pfam Transposase IS66
DBK22_RS12590	COG0791	NLP P60 protein
DBK22_RS12600	COG2843	Capsule synthesis protein
DBK22_RS12610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBK22_RS12615	COG0697	spore germination
DBK22_RS12620	COG0814	amino acid
DBK22_RS12630	COG1609	Transcriptional regulator
DBK22_RS12635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBK22_RS12645	COG1129	ABC transporter
DBK22_RS12650	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBK22_RS12655	COG1879	ABC-type sugar transport system periplasmic component
DBK22_RS12660	COG3103	Sh3 type 3 domain protein
DBK22_RS12665	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBK22_RS12670	COG3527	Alpha-acetolactate decarboxylase
DBK22_RS12675	COG0028	Belongs to the TPP enzyme family
DBK22_RS12680	COG0583	DNA-binding transcription factor activity
DBK22_RS12685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DBK22_RS12700	COG5337	Spore coat protein CotH
DBK22_RS12710	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DBK22_RS12720	COG0405	Gamma-glutamyltransferase
DBK22_RS12725	COG1522	sequence-specific DNA binding
DBK22_RS12730	COG2059	Chromate
DBK22_RS12735	COG2059	Chromate
DBK22_RS12755	COG5444	nuclease activity
DBK22_RS12770	COG3878	Protein conserved in bacteria
DBK22_RS12775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DBK22_RS12780	COG4464	protein tyrosine phosphatase activity
DBK22_RS12785	COG0489	protein tyrosine kinase activity
DBK22_RS12790	COG3944	biosynthesis protein
DBK22_RS12800	COG4715	Zinc finger, swim domain protein
DBK22_RS12805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBK22_RS12810	COG0561	phosphatase activity
DBK22_RS12815	COG1349	DNA-binding transcription factor activity
DBK22_RS12820	COG0629	single-stranded DNA binding
DBK22_RS12845	COG0457	Tetratricopeptide repeat
DBK22_RS12850	COG4786	Flagellar basal body rod
DBK22_RS12855	COG4786	Flagellar basal body rod
DBK22_RS12860	COG1077	Cell shape determining protein MreB Mrl
DBK22_RS12865	COG1609	Transcriptional regulator
DBK22_RS12870	COG1846	Transcriptional regulator
DBK22_RS12875	COG2814	Major facilitator Superfamily
DBK22_RS12885	COG1953	Uracil, thiamine, allantoin
DBK22_RS12890	COG0477	Major facilitator Superfamily
DBK22_RS12895	COG1335	isochorismatase
DBK22_RS12900	COG0004	ammonium transporteR
DBK22_RS12905	COG0347	Belongs to the P(II) protein family
DBK22_RS12910	COG0772	Belongs to the SEDS family
DBK22_RS12915	COG0671	phosphoesterase, PA-phosphatase related
DBK22_RS12925	COG0739	heme binding
DBK22_RS12930	COG1247	-acetyltransferase
DBK22_RS12945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBK22_RS12955	COG0726	polysaccharide deacetylase
DBK22_RS12960	COG1959	2 iron, 2 sulfur cluster binding
DBK22_RS12975	COG0831	urea catabolic process
DBK22_RS12980	COG3237	CsbD-like
DBK22_RS12985	COG1994	Peptidase M50
DBK22_RS12990	COG0457	Tetratricopeptide repeat
DBK22_RS13000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DBK22_RS13005	COG2304	oxidoreductase activity
DBK22_RS13010	COG2304	oxidoreductase activity
DBK22_RS13015	COG2385	sporulation resulting in formation of a cellular spore
DBK22_RS13020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBK22_RS13030	COG4836	Membrane
DBK22_RS13070	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBK22_RS13100	COG0698	ribose 5-phosphate isomerase
DBK22_RS13105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBK22_RS13115	COG0009	L-threonylcarbamoyladenylate synthase
DBK22_RS13120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DBK22_RS13140	COG2890	protein-(glutamine-N5) methyltransferase activity
DBK22_RS13145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DBK22_RS13150	COG0346	lactoylglutathione lyase activity
DBK22_RS13155	COG0789	Transcriptional regulator
DBK22_RS13160	COG0679	Auxin Efflux Carrier
DBK22_RS13165	COG0281	malic enzyme
DBK22_RS13175	COG0254	rRNA binding
DBK22_RS13180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DBK22_RS13185	COG1494	fructose-1,6-bisphosphatase
DBK22_RS13190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBK22_RS13200	COG0191	fructose-bisphosphate aldolase activity
DBK22_RS13205	COG2204	response regulator
DBK22_RS13210	COG4821	SIS domain
DBK22_RS13225	COG2181	nitrate reductase activity
DBK22_RS13225	COG0247	lactate metabolic process
DBK22_RS13230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBK22_RS13245	COG1132	(ABC) transporter
DBK22_RS13250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBK22_RS13260	COG2181	nitrate reductase activity
DBK22_RS13265	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DBK22_RS13270	COG1140	nitrate reductase beta subunit
DBK22_RS13275	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DBK22_RS13280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBK22_RS13290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DBK22_RS13295	COG2223	nitrite transmembrane transporter activity
DBK22_RS13305	COG4506	Protein conserved in bacteria
DBK22_RS13315	COG3391	amine dehydrogenase activity
DBK22_RS13320	COG3391	amine dehydrogenase activity
DBK22_RS13325	COG0457	Tetratricopeptide repeat
DBK22_RS13370	COG0010	Belongs to the arginase family
DBK22_RS13375	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DBK22_RS13380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBK22_RS13395	COG1994	Peptidase M50
DBK22_RS13400	COG1942	4-Oxalocrotonate Tautomerase
DBK22_RS13405	COG1846	Transcriptional regulator
DBK22_RS13410	COG0531	amino acid
DBK22_RS13415	COG3465	dGTPase activity
DBK22_RS13420	COG1078	dGTPase activity
DBK22_RS13435	COG1695	Transcriptional regulator
DBK22_RS13445	COG1131	(ABC) transporter
DBK22_RS13450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DBK22_RS13480	COG0583	DNA-binding transcription factor activity
DBK22_RS13485	COG2855	membrane
DBK22_RS13490	COG0280	phosphate acetyltransferase
DBK22_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS13505	COG0436	Aminotransferase
DBK22_RS13535	COG2814	Major facilitator Superfamily
DBK22_RS13540	COG2814	Major facilitator Superfamily
DBK22_RS13545	COG0833	amino acid
DBK22_RS13550	COG4187	Peptidase family M20/M25/M40
DBK22_RS13555	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS13560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBK22_RS13570	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DBK22_RS13575	COG1091	dTDP-4-dehydrorhamnose reductase activity
DBK22_RS13580	COG1088	dTDP-glucose 4,6-dehydratase activity
DBK22_RS13585	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DBK22_RS13590	COG3980	spore coat polysaccharide biosynthesis protein
DBK22_RS13595	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DBK22_RS13600	COG2089	acid synthase
DBK22_RS13605	COG0456	acetyltransferase
DBK22_RS13610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DBK22_RS13615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DBK22_RS13620	COG0463	Glycosyl transferase, family 2
DBK22_RS13630	COG2363	Small membrane protein
DBK22_RS13635	COG2233	PERMEase
DBK22_RS13650	COG1216	Glycosyl transferase, family 2
DBK22_RS13665	COG1695	Transcriptional regulator
DBK22_RS13670	COG0351	phosphomethylpyrimidine kinase
DBK22_RS13680	COG1621	beta-fructofuranosidase activity
DBK22_RS13685	COG1263	PTS System
DBK22_RS13685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS13690	COG3711	transcriptional antiterminator
DBK22_RS13700	COG1404	Belongs to the peptidase S8 family
DBK22_RS13705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBK22_RS13710	COG0778	Nitroreductase
DBK22_RS13715	COG0772	Belongs to the SEDS family
DBK22_RS13720	COG0454	-acetyltransferase
DBK22_RS13740	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DBK22_RS13745	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DBK22_RS13750	COG2261	transglycosylase associated protein
DBK22_RS13755	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DBK22_RS13760	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DBK22_RS13765	COG2246	polysaccharide biosynthetic process
DBK22_RS13770	COG1309	transcriptional regulator
DBK22_RS13790	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DBK22_RS13795	COG2837	iron assimilation
DBK22_RS13800	COG2822	iron ion transport
DBK22_RS13815	COG0583	DNA-binding transcription factor activity
DBK22_RS13825	COG1346	cytolysis
DBK22_RS13830	COG4895	conserved protein (DUF2196)
DBK22_RS13835	COG0789	Transcriptional regulator
DBK22_RS13840	COG5504	Zn-dependent protease
DBK22_RS13845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DBK22_RS13850	COG0346	lactoylglutathione lyase activity
DBK22_RS13855	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS13860	COG1404	Belongs to the peptidase S8 family
DBK22_RS13865	COG1442	glycosyl transferase family 8
DBK22_RS13870	COG2357	RelA SpoT domain protein
DBK22_RS13875	COG1575	Belongs to the MenA family. Type 1 subfamily
DBK22_RS13890	COG1696	Membrane protein involved in D-alanine export
DBK22_RS13900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DBK22_RS13905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS13910	COG1486	melibiose metabolic process
DBK22_RS13915	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBK22_RS13920	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS13925	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS13930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS13930	COG3711	transcriptional antiterminator
DBK22_RS13940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS13945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS13955	COG0640	Transcriptional regulator
DBK22_RS13960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DBK22_RS13965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS13970	COG1447	Phosphotransferase system cellobiose-specific component IIA
DBK22_RS13975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DBK22_RS13980	COG2723	6-phospho-beta-galactosidase activity
DBK22_RS13985	COG1940	carbohydrate kinase activity
DBK22_RS13990	COG1482	cell wall glycoprotein biosynthetic process
DBK22_RS14000	COG0753	catalase activity
DBK22_RS14005	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DBK22_RS14010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DBK22_RS14015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DBK22_RS14020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBK22_RS14025	COG4988	ABC transporter
DBK22_RS14030	COG1294	oxidase, subunit
DBK22_RS14035	COG1271	oxidase subunit
DBK22_RS14040	COG3493	citrate carrier protein
DBK22_RS14045	COG0726	polysaccharide deacetylase
DBK22_RS14050	COG3842	ATPase activity
DBK22_RS14055	COG2508	Transcriptional regulator
DBK22_RS14060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS14070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBK22_RS14080	COG4894	glucomannan catabolic process
DBK22_RS14085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DBK22_RS14090	COG0500	methyltransferase
DBK22_RS14095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBK22_RS14110	COG0753	catalase activity
DBK22_RS14110	COG0693	protein deglycase activity
DBK22_RS14115	COG2851	Citrate transporter
DBK22_RS14120	COG2273	Hydrolase Family 16
DBK22_RS14125	COG3711	transcriptional antiterminator
DBK22_RS14130	COG2270	Major facilitator Superfamily
DBK22_RS14135	COG0513	Belongs to the DEAD box helicase family
DBK22_RS14230	COG3209	COG3209 Rhs family protein
DBK22_RS14240	COG0697	spore germination
DBK22_RS14245	COG0589	response to stress
DBK22_RS14250	COG2723	6-phospho-beta-galactosidase activity
DBK22_RS14255	COG1263	PTS System
DBK22_RS14255	COG2190	(PTS) system
DBK22_RS14255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS14270	COG3507	Belongs to the glycosyl hydrolase 43 family
DBK22_RS14295	COG0010	Belongs to the arginase family
DBK22_RS14300	COG0833	amino acid
DBK22_RS14305	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DBK22_RS14310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DBK22_RS14320	COG2390	Transcriptional regulator
DBK22_RS14325	COG0561	phosphatase activity
DBK22_RS14355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBK22_RS14360	COG5294	Protein conserved in bacteria
DBK22_RS14365	COG0577	efflux transmembrane transporter activity
DBK22_RS14370	COG1136	(ABC) transporter
DBK22_RS14375	COG2205	protein histidine kinase activity
DBK22_RS14380	COG0745	RESPONSE REGULATOR receiver
DBK22_RS14385	COG2205	protein histidine kinase activity
DBK22_RS14390	COG0745	RESPONSE REGULATOR receiver
DBK22_RS14420	COG1082	Xylose isomerase domain protein TIM barrel
DBK22_RS14430	COG2814	Major facilitator Superfamily
DBK22_RS14460	COG1349	DNA-binding transcription factor activity
DBK22_RS14465	COG0667	Aldo Keto reductase
DBK22_RS14475	COG2814	Major facilitator Superfamily
DBK22_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS14495	COG2197	response regulator
DBK22_RS14500	COG4585	Histidine kinase
DBK22_RS14505	COG3239	Fatty acid desaturase
DBK22_RS14510	COG1309	transcriptional regulator
DBK22_RS14515	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS14520	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DBK22_RS14530	COG0640	Transcriptional regulator
DBK22_RS14535	COG2814	Major facilitator Superfamily
DBK22_RS14540	COG1714	RDD family
DBK22_RS14550	COG0450	alkyl hydroperoxide reductase
DBK22_RS14555	COG3634	alkyl hydroperoxide reductase activity
DBK22_RS14560	COG3177	Filamentation induced by cAMP protein fic
DBK22_RS14565	COG1113	amino acid transport
DBK22_RS14575	COG2080	2 iron, 2 sulfur cluster binding
DBK22_RS14590	COG2068	MobA-Related Protein
DBK22_RS14595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
DBK22_RS14680	COG2003	Belongs to the UPF0758 family
DBK22_RS14710	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DBK22_RS14715	COG0667	Aldo Keto reductase
DBK22_RS14720	COG0456	acetyltransferase
DBK22_RS14725	COG0457	Tetratricopeptide repeat
DBK22_RS14730	COG0010	Belongs to the arginase family
DBK22_RS14735	COG0833	amino acid
DBK22_RS14740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DBK22_RS14745	COG5658	integral membrane protein
DBK22_RS14750	COG0640	Transcriptional regulator
DBK22_RS14755	COG3829	transcription factor binding
DBK22_RS14765	COG0488	(ABC) transporter
DBK22_RS14780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DBK22_RS14785	COG3850	Histidine kinase
DBK22_RS14785	COG5002	protein histidine kinase activity
DBK22_RS14790	COG0745	RESPONSE REGULATOR receiver
DBK22_RS14795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBK22_RS14800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DBK22_RS14805	COG4853	Protein conserved in bacteria
DBK22_RS14810	COG4863	YycH protein
DBK22_RS14815	COG5002	protein histidine kinase activity
DBK22_RS14820	COG0745	RESPONSE REGULATOR receiver
DBK22_RS14850	COG0346	lactoylglutathione lyase activity
DBK22_RS14855	COG0305	Participates in initiation and elongation during chromosome replication
DBK22_RS14875	COG3093	addiction module antidote protein HigA
DBK22_RS14880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DBK22_RS14895	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DBK22_RS14900	COG0438	transferase activity, transferring glycosyl groups
DBK22_RS14920	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DBK22_RS14925	COG4241	membrane
DBK22_RS14935	COG5577	PFAM Coat F domain
DBK22_RS14940	COG1733	regulation of RNA biosynthetic process
DBK22_RS14950	COG0697	spore germination
DBK22_RS14955	COG1621	beta-fructofuranosidase activity
DBK22_RS14960	COG1621	beta-fructofuranosidase activity
DBK22_RS14965	COG1802	Transcriptional regulator
DBK22_RS14970	COG2318	DinB family
DBK22_RS14975	COG2211	Major facilitator Superfamily
DBK22_RS14980	COG0583	DNA-binding transcription factor activity
DBK22_RS14990	COG2814	Major facilitator Superfamily
DBK22_RS14995	COG0583	DNA-binding transcription factor activity
DBK22_RS15005	COG0778	Nitroreductase
DBK22_RS15010	COG1846	Transcriptional regulator
DBK22_RS15015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS15020	COG1846	Transcriptional regulator
DBK22_RS15025	COG2153	protein acetylation
DBK22_RS15035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DBK22_RS15040	COG0583	DNA-binding transcription factor activity
DBK22_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS15050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS15055	COG0697	spore germination
DBK22_RS15060	COG1331	Highly conserved protein containing a thioredoxin domain
DBK22_RS15065	COG1266	CAAX protease self-immunity
DBK22_RS15070	COG2814	Major facilitator Superfamily
DBK22_RS15070	COG0477	Major facilitator Superfamily
DBK22_RS15075	COG0346	lactoylglutathione lyase activity
DBK22_RS15080	COG1609	Transcriptional regulator
DBK22_RS15085	COG0708	Exodeoxyribonuclease III
DBK22_RS15090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBK22_RS15095	COG2169	Transcriptional regulator
DBK22_RS15105	COG0629	single-stranded DNA binding
DBK22_RS15115	COG0012	GTP binding
DBK22_RS15120	COG0243	molybdopterin cofactor binding
DBK22_RS15125	COG4481	Protein conserved in bacteria
DBK22_RS15130	COG3949	Membrane
DBK22_RS15145	COG1475	DNA binding
DBK22_RS15150	COG1192	Involved in chromosome partitioning
DBK22_RS15175	COG1847	R3H domain protein
DBK22_RS15180	COG0706	membrane insertase activity
DBK22_RS15190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DBK22_RS15200	COG0592	DNA-directed DNA polymerase activity
DBK22_RS15205	COG2501	S4 domain
DBK22_RS15220	COG0187	DNA topoisomerase II activity
DBK22_RS15225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBK22_RS15260	COG0517	IMP dehydrogenase activity
DBK22_RS15260	COG0516	GMP reductase activity
DBK22_RS15265	COG1686	Belongs to the peptidase S11 family
DBK22_RS15285	COG1929	Belongs to the glycerate kinase type-1 family
DBK22_RS15295	COG1428	Deoxynucleoside kinase
DBK22_RS15300	COG1428	Deoxynucleoside kinase
DBK22_RS15305	COG3858	chitin binding
DBK22_RS15305	COG1388	LysM domain
DBK22_RS15310	COG1335	isochorismatase
DBK22_RS15315	COG0590	tRNA wobble adenosine to inosine editing
DBK22_RS15325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBK22_RS15330	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DBK22_RS15380	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DBK22_RS15385	COG3853	Toxic anion resistance protein (TelA)
DBK22_RS15390	COG1982	Orn Lys Arg decarboxylase major
DBK22_RS15400	COG3870	Protein conserved in bacteria
DBK22_RS15405	COG1728	Protein conserved in bacteria
DBK22_RS15410	COG0470	DNA polymerase III
DBK22_RS15415	COG1774	PSP1 C-terminal conserved region
DBK22_RS15425	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DBK22_RS15435	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DBK22_RS15440	COG2002	toxin-antitoxin pair type II binding
DBK22_RS15445	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBK22_RS15445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBK22_RS15450	COG0084	hydrolase, TatD family'
DBK22_RS15455	COG3583	domain protein
DBK22_RS15455	COG3584	3D domain protein
DBK22_RS15460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DBK22_RS15465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DBK22_RS15475	COG4466	Protein conserved in bacteria
DBK22_RS15490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBK22_RS15495	COG0251	oxidation-reduction process
DBK22_RS15510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DBK22_RS15530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DBK22_RS15535	COG2002	toxin-antitoxin pair type II binding
DBK22_RS15540	COG2244	polysaccharide biosynthetic process
DBK22_RS15545	COG3956	TIGRFAM MazG family protein
DBK22_RS15550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DBK22_RS15565	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DBK22_RS15570	COG1098	S1 RNA binding domain
DBK22_RS15585	COG2208	phosphoserine phosphatase activity
DBK22_RS15590	COG2304	oxidoreductase activity
DBK22_RS15595	COG0515	serine threonine protein kinase
DBK22_RS15600	COG0037	tRNA processing
DBK22_RS15610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBK22_RS15625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DBK22_RS15630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DBK22_RS15635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DBK22_RS15640	COG0512	Glutamine amidotransferase of anthranilate synthase
DBK22_RS15645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS15650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DBK22_RS15655	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DBK22_RS15660	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBK22_RS15665	COG1396	sequence-specific DNA binding
DBK22_RS15670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBK22_RS15675	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DBK22_RS15755	COG4463	regulation of RNA biosynthetic process
DBK22_RS15760	COG3880	PFAM UvrB UvrC protein
DBK22_RS15770	COG0542	response to heat
DBK22_RS15775	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBK22_RS15780	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DBK22_RS15785	COG4956	integral membrane protein (PIN domain superfamily)
DBK22_RS15805	COG1045	serine acetyltransferase
DBK22_RS15815	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DBK22_RS15820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBK22_RS15825	COG3688	RNA-binding protein containing a PIN domain
DBK22_RS15830	COG1595	DNA-templated transcription, initiation
DBK22_RS15835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DBK22_RS15840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBK22_RS15845	COG0250	Participates in transcription elongation, termination and antitermination
DBK22_RS15850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DBK22_RS15865	COG0222	ribosome binding
DBK22_RS15870	COG2813	Specifically methylates the guanine in position
DBK22_RS15885	COG1358	cellular component organization or biogenesis
DBK22_RS15910	COG0596	Alpha beta hydrolase
DBK22_RS15915	COG0051	transcription antitermination factor activity, RNA binding
DBK22_RS15930	COG0089	rRNA binding
DBK22_RS15940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBK22_RS15945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBK22_RS15955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBK22_RS15960	COG0255	Belongs to the universal ribosomal protein uL29 family
DBK22_RS16010	COG1841	ribosomal large subunit assembly
DBK22_RS16020	COG0201	protein transport
DBK22_RS16030	COG0024	Methionine aminopeptidase
DBK22_RS16040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBK22_RS16045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DBK22_RS16070	COG1122	ATPase activity
DBK22_RS16075	COG1122	ATPase activity
DBK22_RS16080	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBK22_RS16100	COG2226	methyltransferase
DBK22_RS16105	COG2318	DinB family
DBK22_RS16115	COG0860	N-Acetylmuramoyl-L-alanine amidase
DBK22_RS16120	COG0489	protein tyrosine kinase activity
DBK22_RS16130	COG2194	sulfuric ester hydrolase activity
DBK22_RS16135	COG0726	polysaccharide deacetylase
DBK22_RS16195	COG0738	Major facilitator superfamily
DBK22_RS16200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS16215	COG0659	secondary active sulfate transmembrane transporter activity
DBK22_RS16220	COG0385	Bile acid
DBK22_RS16225	COG2819	hydrolase of the alpha beta superfamily
DBK22_RS16230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS16235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS16240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBK22_RS16245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBK22_RS16245	COG2207	Transcriptional regulator
DBK22_RS16250	COG3876	Protein conserved in bacteria
DBK22_RS16255	COG1472	Belongs to the glycosyl hydrolase 3 family
DBK22_RS16260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DBK22_RS16265	COG1263	PTS System
DBK22_RS16265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS16275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBK22_RS16280	COG1683	Conserved Protein
DBK22_RS16310	COG1595	DNA-templated transcription, initiation
DBK22_RS16315	COG5662	AntiSigma factor
DBK22_RS16320	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DBK22_RS16325	COG4856	YbbR-like protein
DBK22_RS16365	COG1346	cytolysis
DBK22_RS16370	COG1380	Effector of murein hydrolase LrgA
DBK22_RS16375	COG1846	Transcriptional regulator
DBK22_RS16380	COG1113	amino acid transport
DBK22_RS16385	COG1011	Hydrolase
DBK22_RS16390	COG4585	Histidine kinase
DBK22_RS16395	COG2197	response regulator
DBK22_RS16400	COG1131	(ABC) transporter
DBK22_RS16420	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DBK22_RS16440	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS16440	COG3321	synthase
DBK22_RS16440	COG4221	oxidoreductase activity
DBK22_RS16445	COG3321	synthase
DBK22_RS16445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS16445	COG0300	oxidoreductase activity
DBK22_RS16445	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS16485	COG0531	amino acid
DBK22_RS16495	COG0584	glycerophosphoryl diester phosphodiesterase
DBK22_RS16500	COG2271	Major facilitator Superfamily
DBK22_RS16510	COG2368	4-hydroxyphenylacetate
DBK22_RS16520	COG3409	Peptidoglycan-binding domain 1 protein
DBK22_RS16535	COG1397	ADP-ribosylglycohydrolase
DBK22_RS16540	COG5444	nuclease activity
DBK22_RS16550	COG0371	Dehydrogenase
DBK22_RS16560	COG1183	phosphatidylcholine synthase activity
DBK22_RS16565	COG0586	Pfam SNARE associated Golgi protein
DBK22_RS16570	COG0688	phosphatidylethanolamine metabolic process
DBK22_RS16585	COG1301	dicarboxylic acid transport
DBK22_RS16590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS16595	COG0833	amino acid
DBK22_RS16600	COG2040	homocysteine
DBK22_RS16605	COG1115	amino acid carrier protein
DBK22_RS16610	COG2066	Belongs to the glutaminase family
DBK22_RS16615	COG4191	Histidine kinase
DBK22_RS16620	COG0784	Response regulator, receiver
DBK22_RS16635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBK22_RS16640	COG0778	Nitroreductase
DBK22_RS16645	COG0346	lactoylglutathione lyase activity
DBK22_RS16650	COG2259	Doxx family
DBK22_RS16655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS16665	COG3773	Cell wall hydrolase
DBK22_RS16670	COG3540	Alkaline phosphatase
DBK22_RS16675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBK22_RS16680	COG0805	protein transport
DBK22_RS16690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DBK22_RS16695	COG0477	Major facilitator Superfamily
DBK22_RS16700	COG1309	transcriptional regulator
DBK22_RS16705	COG0252	asparaginase activity
DBK22_RS16710	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DBK22_RS16715	COG1405	negative regulation of cell septum assembly
DBK22_RS16715	COG3012	SEC-C Motif Domain Protein
DBK22_RS16720	COG0667	Aldo Keto reductase
DBK22_RS16730	COG1595	DNA-templated transcription, initiation
DBK22_RS16735	COG1595	DNA-templated transcription, initiation
DBK22_RS16740	COG1876	peptidase activity
DBK22_RS16745	COG0457	Tetratricopeptide repeat
DBK22_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS16755	COG0366	Alpha amylase catalytic
DBK22_RS16760	COG0803	Belongs to the bacterial solute-binding protein 9 family
DBK22_RS16765	COG1121	(ABC) transporter
DBK22_RS16770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBK22_RS16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DBK22_RS16780	COG2310	stress, protein
DBK22_RS16785	COG2310	stress, protein
DBK22_RS16790	COG2310	stress, protein
DBK22_RS16795	COG0861	Integral membrane protein TerC family
DBK22_RS16805	COG3853	Toxic anion resistance protein (TelA)
DBK22_RS16810	COG0477	Major facilitator Superfamily
DBK22_RS16815	COG0517	IMP dehydrogenase activity
DBK22_RS16815	COG4175	Glycine betaine
DBK22_RS16820	COG4176	ABC-type proline glycine betaine transport system permease component
DBK22_RS16825	COG2113	Glycine betaine
DBK22_RS16830	COG1473	amidohydrolase
DBK22_RS16835	COG1288	antiporter activity
DBK22_RS16845	COG0366	Alpha amylase catalytic
DBK22_RS16855	COG2814	Major facilitator Superfamily
DBK22_RS16860	COG1846	Transcriptional regulator
DBK22_RS16865	COG1280	lysine exporter protein (LysE YggA)
DBK22_RS16870	COG3403	YqcI/YcgG family
DBK22_RS16875	COG1113	amino acid transport
DBK22_RS16880	COG3665	Urea carboxylase-associated protein
DBK22_RS16895	COG1660	Displays ATPase and GTPase activities
DBK22_RS16900	COG1082	Xylose isomerase domain protein TIM barrel
DBK22_RS16905	COG2271	Major facilitator Superfamily
DBK22_RS16910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBK22_RS16915	COG3458	cephalosporin-C deacetylase activity
DBK22_RS16920	COG3541	Predicted nucleotidyltransferase
DBK22_RS16925	COG0506	proline dehydrogenase activity
DBK22_RS16930	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS16935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBK22_RS16940	COG2508	Transcriptional regulator
DBK22_RS16950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DBK22_RS16950	COG1587	Uroporphyrinogen-III synthase
DBK22_RS16955	COG2146	nitrite reductase [NAD(P)H] activity
DBK22_RS16960	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBK22_RS16965	COG0243	molybdopterin cofactor binding
DBK22_RS16970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DBK22_RS16975	COG2223	nitrite transmembrane transporter activity
DBK22_RS16980	COG0523	cobalamin synthesis protein
DBK22_RS16985	COG1063	alcohol dehydrogenase
DBK22_RS16990	COG1714	RDD family
DBK22_RS17000	COG2723	6-phospho-beta-galactosidase activity
DBK22_RS17010	COG3209	COG3209 Rhs family protein
DBK22_RS17015	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DBK22_RS17020	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DBK22_RS17025	COG1733	regulation of RNA biosynthetic process
DBK22_RS17030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS17035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS17040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DBK22_RS17045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DBK22_RS17060	COG0697	spore germination
DBK22_RS17065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS17075	COG2364	Membrane
DBK22_RS17080	COG1126	abc transporter atp-binding protein
DBK22_RS17085	COG0765	amino acid transport
DBK22_RS17090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS17095	COG0583	DNA-binding transcription factor activity
DBK22_RS17100	COG0163	prenyltransferase activity
DBK22_RS17105	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DBK22_RS17120	COG3104	oligopeptide transport
DBK22_RS17125	COG5434	Belongs to the glycosyl hydrolase 28 family
DBK22_RS17135	COG0697	spore germination
DBK22_RS17145	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DBK22_RS17160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DBK22_RS17165	COG0765	amino acid transport
DBK22_RS17170	COG1126	abc transporter atp-binding protein
DBK22_RS17180	COG2079	MmgE PrpD family protein
DBK22_RS17185	COG1136	(ABC) transporter
DBK22_RS17190	COG0577	efflux transmembrane transporter activity
DBK22_RS17195	COG0745	RESPONSE REGULATOR receiver
DBK22_RS17200	COG5002	protein histidine kinase activity
DBK22_RS17200	COG3850	Histidine kinase
DBK22_RS17205	COG0457	Tetratricopeptide repeat
DBK22_RS17220	COG0527	aspartate kinase activity
DBK22_RS17225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBK22_RS17230	COG4605	iron ion homeostasis
DBK22_RS17235	COG4604	ABC transporter, ATP-binding protein
DBK22_RS17240	COG4607	ABC-type enterochelin transport system periplasmic component
DBK22_RS17245	COG2814	Major facilitator Superfamily
DBK22_RS17250	COG1309	transcriptional regulator
DBK22_RS17255	COG0778	Nitroreductase
DBK22_RS17260	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DBK22_RS17265	COG0640	Transcriptional regulator
DBK22_RS17270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS17275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DBK22_RS17280	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS17290	COG4975	Glucose uptake
DBK22_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS17300	COG4549	nuclear export factor GLE1
DBK22_RS17305	COG2372	response to copper ion
DBK22_RS17305	COG1276	copper resistance
DBK22_RS17310	COG1349	DNA-binding transcription factor activity
DBK22_RS17320	COG2213	PTS system mannitol-specific
DBK22_RS17325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBK22_RS17335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DBK22_RS17345	COG0561	phosphatase activity
DBK22_RS17355	COG1914	H( )-stimulated, divalent metal cation uptake system
DBK22_RS17365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DBK22_RS17370	COG1984	allophanate hydrolase subunit 2
DBK22_RS17375	COG1414	Transcriptional regulator
DBK22_RS17380	COG2755	lipolytic protein G-D-S-L family
DBK22_RS17390	COG2329	Antibiotic biosynthesis monooxygenase
DBK22_RS17395	COG0768	penicillin binding
DBK22_RS17405	COG3711	transcriptional antiterminator
DBK22_RS17410	COG0318	PFAM AMP-dependent synthetase and ligase
DBK22_RS17415	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS17420	COG1917	Cupin 2, conserved barrel domain protein
DBK22_RS17425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBK22_RS17430	COG3871	stress protein (general stress protein 26)
DBK22_RS17445	COG2814	Major facilitator Superfamily
DBK22_RS17450	COG1522	sequence-specific DNA binding
DBK22_RS17455	COG0551	DNA topoisomerase type I activity
DBK22_RS17455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBK22_RS17460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DBK22_RS17465	COG3706	GGDEF domain
DBK22_RS17470	COG5298	Protein conserved in bacteria
DBK22_RS17475	COG1215	transferase activity, transferring glycosyl groups
DBK22_RS17485	COG0531	amino acid
DBK22_RS17490	COG0494	nUDIX hydrolase
DBK22_RS17495	COG0028	Belongs to the TPP enzyme family
DBK22_RS17520	COG1914	H( )-stimulated, divalent metal cation uptake system
DBK22_RS17530	COG4876	unkown
DBK22_RS17540	COG2076	Multidrug Resistance protein
DBK22_RS17545	COG2217	Heavy metal translocating P-type atpase
DBK22_RS17550	COG3729	General stress protein
DBK22_RS17555	COG0662	Cupin 2, conserved barrel domain protein
DBK22_RS17560	COG2329	Antibiotic biosynthesis monooxygenase
DBK22_RS17565	COG3546	catalase activity
DBK22_RS17570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBK22_RS17575	COG3290	protein histidine kinase activity
DBK22_RS17580	COG4565	transcriptional regulatory protein
DBK22_RS17585	COG1301	dicarboxylic acid transport
DBK22_RS17590	COG0628	permease
DBK22_RS17595	COG1131	(ABC) transporter
DBK22_RS17600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DBK22_RS17610	COG1960	acyl-CoA dehydrogenase activity
DBK22_RS17625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBK22_RS17630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBK22_RS17640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DBK22_RS17645	COG0513	Belongs to the DEAD box helicase family
DBK22_RS17650	COG3402	PFAM membrane-flanked domain
DBK22_RS17655	COG3428	Bacterial PH domain
DBK22_RS17660	COG0705	Rhomboid family
DBK22_RS17670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DBK22_RS17675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBK22_RS17680	COG0864	Transcriptional regulator
DBK22_RS17685	COG2337	Toxic component of a toxin-antitoxin (TA) module
DBK22_RS17690	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS17695	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS17700	COG2172	sigma factor antagonist activity
DBK22_RS17705	COG2208	phosphoserine phosphatase activity
DBK22_RS17710	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS17720	COG1191	sigma factor activity
DBK22_RS17725	COG2208	phosphoserine phosphatase activity
DBK22_RS17730	COG2183	response to ionizing radiation
DBK22_RS17795	COG0604	alcohol dehydrogenase
DBK22_RS17805	COG1959	2 iron, 2 sulfur cluster binding
DBK22_RS17810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DBK22_RS17815	COG1090	epimerase
DBK22_RS17820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DBK22_RS17835	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBK22_RS17845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBK22_RS17850	COG0477	Major facilitator Superfamily
DBK22_RS17855	COG1846	Transcriptional regulator
DBK22_RS17865	COG2030	dehydratase
DBK22_RS17880	COG1959	2 iron, 2 sulfur cluster binding
DBK22_RS17885	COG2910	NAD(P)H-binding
DBK22_RS17890	COG3239	Fatty acid desaturase
DBK22_RS17900	COG1278	Cold shock
DBK22_RS17905	COG1329	Transcriptional regulator
DBK22_RS17910	COG1794	racemase activity, acting on amino acids and derivatives
DBK22_RS17925	COG1846	Transcriptional regulator
DBK22_RS17925	COG0456	acetyltransferase
DBK22_RS17930	COG2271	Major facilitator Superfamily
DBK22_RS17935	COG3621	Patatin-like phospholipase
DBK22_RS17945	COG0662	Cupin 2, conserved barrel domain protein
DBK22_RS17960	COG0277	FAD linked oxidase domain protein
DBK22_RS17985	COG0662	Cupin 2, conserved barrel domain protein
DBK22_RS17990	COG2318	DinB family
DBK22_RS17995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBK22_RS18020	COG1064	alcohol dehydrogenase
DBK22_RS18025	COG0789	Transcriptional regulator
DBK22_RS18035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS18050	COG2814	Major facilitator Superfamily
DBK22_RS18055	COG1309	transcriptional regulator
DBK22_RS18060	COG0697	spore germination
DBK22_RS18065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBK22_RS18070	COG5577	PFAM Coat F domain
DBK22_RS18080	COG1063	alcohol dehydrogenase
DBK22_RS18085	COG5577	PFAM Coat F domain
DBK22_RS18100	COG2197	response regulator
DBK22_RS18105	COG2409	Drug exporters of the RND superfamily
DBK22_RS18110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DBK22_RS18120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DBK22_RS18125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DBK22_RS18135	COG2814	Major facilitator Superfamily
DBK22_RS18140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DBK22_RS18150	COG0730	response to heat
DBK22_RS18155	COG0456	acetyltransferase
DBK22_RS18165	COG1051	belongs to the nudix hydrolase family
DBK22_RS18170	COG2226	methyltransferase
DBK22_RS18175	COG0473	3-isopropylmalate dehydrogenase activity
DBK22_RS18180	COG1802	Transcriptional regulator
DBK22_RS18185	COG1819	glycosyl
DBK22_RS18200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DBK22_RS18205	COG1388	LysM domain
DBK22_RS18210	COG2814	Major facilitator Superfamily
DBK22_RS18215	COG2188	Transcriptional regulator
DBK22_RS18220	COG2186	Transcriptional regulator
DBK22_RS18225	COG2807	transmembrane transport
DBK22_RS18230	COG2076	Multidrug Resistance protein
DBK22_RS18235	COG2076	Multidrug Resistance protein
DBK22_RS18240	COG1309	transcriptional regulator
DBK22_RS18245	COG0531	amino acid
DBK22_RS18255	COG3832	glyoxalase III activity
DBK22_RS18260	COG0604	alcohol dehydrogenase
DBK22_RS18265	COG2814	Major facilitator Superfamily
DBK22_RS18305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DBK22_RS18310	COG0802	atpase or kinase
DBK22_RS18315	COG1214	PFAM Peptidase M22, glycoprotease
DBK22_RS18320	COG0456	acetyltransferase
DBK22_RS18325	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBK22_RS18330	COG0488	(ABC) transporter
DBK22_RS18345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBK22_RS18350	COG0805	protein transport
DBK22_RS18360	COG1266	CAAX protease self-immunity
DBK22_RS18365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBK22_RS18375	COG0745	RESPONSE REGULATOR receiver
DBK22_RS18390	COG3290	protein histidine kinase activity
DBK22_RS18470	COG0457	Tetratricopeptide repeat
DBK22_RS18475	COG1063	alcohol dehydrogenase
DBK22_RS18480	COG2211	Major facilitator Superfamily
DBK22_RS18485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBK22_RS18495	COG1842	Phage shock protein A
DBK22_RS18500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBK22_RS18505	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DBK22_RS18510	COG4260	virion core protein, lumpy skin disease virus
DBK22_RS18515	COG2755	lipolytic protein G-D-S-L family
DBK22_RS18515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DBK22_RS18525	COG1595	DNA-templated transcription, initiation
DBK22_RS18530	COG1063	alcohol dehydrogenase
DBK22_RS18535	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DBK22_RS18540	COG0823	Involved in the tonB-independent uptake of proteins
DBK22_RS18550	COG2132	Multicopper oxidase
DBK22_RS18555	COG1113	amino acid transport
DBK22_RS18560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBK22_RS18565	COG0714	Associated with various cellular activities
DBK22_RS18570	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DBK22_RS18575	COG1305	Transglutaminase-like
DBK22_RS18595	COG2252	PERMEase
DBK22_RS18600	COG3064	Membrane
DBK22_RS18620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBK22_RS18625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DBK22_RS18630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBK22_RS18635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DBK22_RS18640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBK22_RS18655	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBK22_RS18665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBK22_RS18670	COG0138	bifunctional purine biosynthesis protein purh
DBK22_RS18675	COG0151	Belongs to the GarS family
DBK22_RS18685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DBK22_RS18690	COG1470	cell adhesion involved in biofilm formation
DBK22_RS18695	COG4496	protein, YerC YecD
DBK22_RS18700	COG0069	glutamate synthase activity
DBK22_RS18710	COG0210	DNA helicase
DBK22_RS18720	COG4851	CamS sex pheromone cAM373 precursor
DBK22_RS18725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DBK22_RS18730	COG1285	pathogenesis
DBK22_RS18735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBK22_RS18755	COG1309	transcriptional regulator
DBK22_RS18760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DBK22_RS18765	COG1597	lipid kinase activity
DBK22_RS18770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBK22_RS18780	COG1131	(ABC) transporter
DBK22_RS18805	COG5444	nuclease activity
DBK22_RS18835	COG3546	catalase activity
DBK22_RS18840	COG0454	-acetyltransferase
DBK22_RS18850	COG2323	membrane
DBK22_RS18860	COG2329	Antibiotic biosynthesis monooxygenase
DBK22_RS18865	COG0346	lactoylglutathione lyase activity
DBK22_RS18870	COG1366	Belongs to the anti-sigma-factor antagonist family
DBK22_RS18875	COG5583	Uncharacterized small protein (DUF2292)
DBK22_RS18880	COG0196	riboflavin kinase activity
DBK22_RS18885	COG0670	Belongs to the BI1 family
DBK22_RS18890	COG1846	Transcriptional regulator
DBK22_RS18895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DBK22_RS18905	COG2124	cytochrome p450
DBK22_RS18905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DBK22_RS18920	COG1131	(ABC) transporter
DBK22_RS18930	COG1368	sulfuric ester hydrolase activity
DBK22_RS18935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DBK22_RS18940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DBK22_RS18945	COG1442	glycosyl transferase family 8
DBK22_RS18950	COG1216	Glycosyl transferase, family 2
DBK22_RS18955	COG1442	glycosyl transferase family 8
DBK22_RS18960	COG2223	nitrite transmembrane transporter activity
DBK22_RS18965	COG0531	amino acid
DBK22_RS18970	COG1012	belongs to the aldehyde dehydrogenase family
DBK22_RS18975	COG0840	transmembrane signaling receptor activity
DBK22_RS18980	COG1028	Short-chain dehydrogenase reductase Sdr
DBK22_RS18985	COG0463	Glycosyl transferase, family 2
DBK22_RS18985	COG0457	Tetratricopeptide repeat
DBK22_RS18990	COG0488	(ABC) transporter
DBK22_RS18995	COG0789	Transcriptional regulator
DBK22_RS19000	COG2814	Major facilitator Superfamily
DBK22_RS19005	COG0488	(ABC) transporter
DBK22_RS19010	COG0513	Belongs to the DEAD box helicase family
DBK22_RS19020	COG2130	NADP-dependent
DBK22_RS19035	COG3866	Pectate lyase
DBK22_RS19040	COG0471	metal ion transport
DBK22_RS19060	COG0745	RESPONSE REGULATOR receiver
DBK22_RS19060	COG2972	Histidine kinase
DBK22_RS19065	COG3279	Response regulator of the LytR AlgR family
DBK22_RS19075	COG3764	Sortase (surface protein transpeptidase)
DBK22_RS19080	COG3290	protein histidine kinase activity
DBK22_RS19085	COG4565	transcriptional regulatory protein
DBK22_RS19090	COG3181	Tripartite tricarboxylate transporter family receptor
DBK22_RS19095	COG2851	Citrate transporter
DBK22_RS19100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBK22_RS19105	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DBK22_RS19115	COG2258	MOSC domain
DBK22_RS19135	COG0024	Methionine aminopeptidase
DBK22_RS19140	COG1263	PTS System
DBK22_RS19140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS19150	COG1368	sulfuric ester hydrolase activity
DBK22_RS19160	COG0071	Belongs to the small heat shock protein (HSP20) family
DBK22_RS19175	COG1263	PTS System
DBK22_RS19175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS19180	COG0366	Alpha amylase catalytic
DBK22_RS19185	COG2188	Transcriptional regulator
DBK22_RS19190	COG0778	Nitroreductase
DBK22_RS19205	COG0737	Belongs to the 5'-nucleotidase family
DBK22_RS19210	COG0693	protein deglycase activity
DBK22_RS19215	COG1609	Transcriptional regulator
DBK22_RS19220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBK22_RS19230	COG2814	Major facilitator Superfamily
DBK22_RS19240	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DBK22_RS19245	COG4980	gas vesicle protein
DBK22_RS19250	COG1295	ribonuclease BN
DBK22_RS19255	COG0477	Major facilitator Superfamily
DBK22_RS19260	COG0387	Pfam Sodium calcium exchanger
DBK22_RS19270	COG0668	transmembrane transport
DBK22_RS19275	COG0535	radical SAM domain protein
DBK22_RS19285	COG0726	polysaccharide deacetylase
DBK22_RS19290	COG2084	Dehydrogenase
DBK22_RS19300	COG0598	Magnesium transport protein CorA
DBK22_RS19305	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DBK22_RS19310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DBK22_RS19320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DBK22_RS19325	COG4637	Psort location Cytoplasmic, score
DBK22_RS19330	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DBK22_RS19335	COG0022	dehydrogenase e1 component
DBK22_RS19340	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBK22_RS19345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBK22_RS19350	COG3284	Transcriptional regulator
DBK22_RS19360	COG1486	melibiose metabolic process
DBK22_RS19365	COG1737	Transcriptional regulator
DBK22_RS19370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBK22_RS19370	COG1263	PTS System
DBK22_RS19375	COG5434	Belongs to the glycosyl hydrolase 28 family
DBK22_RS19380	COG1132	(ABC) transporter
DBK22_RS19385	COG1132	(ABC) transporter
DBK22_RS19390	COG2259	Doxx family
DBK22_RS19395	COG2514	catechol 2,3-dioxygenase activity
DBK22_RS19405	COG1695	Transcriptional regulator
DBK22_RS19410	COG2249	NAD(P)H dehydrogenase (quinone) activity
DBK22_RS19415	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
DBK22_RS19420	COG0574	Belongs to the PEP-utilizing enzyme family
DBK22_RS19420	COG3848	Pyruvate phosphate dikinase
DBK22_RS19425	COG2732	(Barnase) inhibitor
DBK22_RS19430	COG2318	DinB family
DBK22_RS19435	COG2814	Major facilitator Superfamily
DBK22_RS19440	COG1846	Transcriptional regulator
DBK22_RS19445	COG0392	lysyltransferase activity
DBK22_RS19445	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DBK22_RS19450	COG0384	phenazine biosynthesis protein PhzF
DBK22_RS19455	COG0778	Nitroreductase
DBK22_RS19470	COG1090	epimerase
DBK22_RS19485	COG2814	Major facilitator Superfamily
DBK22_RS19495	COG3591	Belongs to the peptidase S1B family
DBK22_RS19510	COG3103	Sh3 type 3 domain protein
DBK22_RS19515	COG5658	integral membrane protein
DBK22_RS19520	COG0596	Alpha beta hydrolase
DBK22_RS19525	COG0463	Glycosyl transferase, family 2
DBK22_RS19530	COG4485	Bacterial membrane protein, YfhO
DBK22_RS19535	COG1988	membrane-bound metal-dependent
DBK22_RS19540	COG1194	a g-specific adenine glycosylase
DBK22_RS19550	COG1028	Short-chain dehydrogenase reductase Sdr