locus-tag	class	description
C7M18_RS00015	COG2814	Major facilitator Superfamily
C7M18_RS00025	COG0456	acetyltransferase
C7M18_RS00030	COG2318	DinB family
C7M18_RS00040	COG0561	phosphatase activity
C7M18_RS00045	COG0561	phosphatase activity
C7M18_RS00055	COG1482	cell wall glycoprotein biosynthetic process
C7M18_RS00060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M18_RS00060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M18_RS00060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS00065	COG3711	transcriptional antiterminator
C7M18_RS00065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS00075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7M18_RS00080	COG0583	DNA-binding transcription factor activity
C7M18_RS00085	COG2814	Major facilitator Superfamily
C7M18_RS00090	COG2124	cytochrome p450
C7M18_RS00090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M18_RS00095	COG1309	transcriptional regulator
C7M18_RS00100	COG2226	methyltransferase
C7M18_RS00110	COG2116	formate transmembrane transporter activity
C7M18_RS00115	COG5609	conserved protein (DUF2294)
C7M18_RS00120	COG3383	formate dehydrogenase (NAD+) activity
C7M18_RS00125	COG2427	Protein of unknown function (DUF1641)
C7M18_RS00135	COG0626	cystathionine gamma-synthase activity
C7M18_RS00140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M18_RS00165	COG0768	penicillin binding
C7M18_RS00195	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M18_RS00210	COG4472	Bacterial protein of unknown function (DUF965)
C7M18_RS00220	COG0628	permease
C7M18_RS00225	COG1126	abc transporter atp-binding protein
C7M18_RS00230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS00235	COG0765	amino acid transport
C7M18_RS00240	COG0765	amino acid transport
C7M18_RS00255	COG3881	PFAM PRC-barrel domain
C7M18_RS00260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M18_RS00265	COG0457	Tetratricopeptide repeat
C7M18_RS00275	COG1104	cysteine desulfurase activity
C7M18_RS00280	COG1959	2 iron, 2 sulfur cluster binding
C7M18_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M18_RS00290	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M18_RS00315	COG4991	sh3 domain protein
C7M18_RS00315	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS00315	COG3103	Sh3 type 3 domain protein
C7M18_RS00325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M18_RS00335	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M18_RS00335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M18_RS00340	COG5416	Lipopolysaccharide assembly protein A domain
C7M18_RS00345	COG0490	domain, Protein
C7M18_RS00350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M18_RS00350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M18_RS00360	COG2244	polysaccharide biosynthetic process
C7M18_RS00365	COG2323	membrane
C7M18_RS00375	COG1862	Preprotein translocase
C7M18_RS00420	COG1388	LysM domain
C7M18_RS00430	COG0157	Belongs to the NadC ModD family
C7M18_RS00435	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M18_RS00440	COG1104	cysteine desulfurase activity
C7M18_RS00445	COG1827	regulation of RNA biosynthetic process
C7M18_RS00450	COG0077	Prephenate dehydratase
C7M18_RS00465	COG3290	protein histidine kinase activity
C7M18_RS00470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M18_RS00475	COG2868	ribosomal protein
C7M18_RS00485	COG1994	Peptidase M50
C7M18_RS00490	COG0739	heme binding
C7M18_RS00495	COG2894	cell division
C7M18_RS00505	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M18_RS00510	COG1792	Involved in formation and maintenance of cell shape
C7M18_RS00515	COG1077	Cell shape determining protein MreB Mrl
C7M18_RS00535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M18_RS00540	COG0285	dihydrofolate synthase activity
C7M18_RS00545	COG0525	valine-tRNA ligase activity
C7M18_RS00555	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M18_RS00560	COG1388	LysM domain
C7M18_RS00570	COG0113	porphobilinogen synthase activity
C7M18_RS00575	COG1587	Uroporphyrinogen-III synthase
C7M18_RS00585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M18_RS00605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M18_RS00610	COG0470	DNA polymerase III
C7M18_RS00610	COG1067	ATP-dependent peptidase activity
C7M18_RS00625	COG0457	Tetratricopeptide repeat
C7M18_RS00625	COG1477	protein flavinylation
C7M18_RS00640	COG0473	3-isopropylmalate dehydrogenase activity
C7M18_RS00655	COG0440	acetolactate synthase activity
C7M18_RS00660	COG0028	Belongs to the TPP enzyme family
C7M18_RS00690	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C7M18_RS00715	COG0622	Phosphoesterase
C7M18_RS00720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M18_RS00730	COG5401	PFAM Sporulation and spore germination
C7M18_RS00740	COG1846	Transcriptional regulator
C7M18_RS00745	COG2197	response regulator
C7M18_RS00750	COG0824	Thioesterase
C7M18_RS00755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M18_RS00760	COG1053	succinate dehydrogenase
C7M18_RS00765	COG2009	succinate dehydrogenase
C7M18_RS00770	COG1719	4-vinyl reductase, 4VR
C7M18_RS00775	COG0527	aspartate kinase activity
C7M18_RS00785	COG3118	belongs to the thioredoxin family
C7M18_RS00790	COG3534	alpha-L-arabinofuranosidase
C7M18_RS00795	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M18_RS00800	COG2086	electron transfer activity
C7M18_RS00805	COG1024	Enoyl-CoA hydratase
C7M18_RS00810	COG1309	transcriptional regulator
C7M18_RS00815	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS00825	COG3766	membrane
C7M18_RS00835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M18_RS00835	COG1796	DNA polymerase
C7M18_RS00840	COG1286	toxin biosynthetic process
C7M18_RS00855	COG0072	phenylalanine-tRNA ligase activity
C7M18_RS00855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M18_RS00860	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M18_RS00865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M18_RS00875	COG3835	regulator
C7M18_RS00880	COG0277	FAD linked oxidase domain protein
C7M18_RS00885	COG0247	lactate metabolic process
C7M18_RS00890	COG1966	Carbon starvation protein
C7M18_RS00895	COG3534	alpha-L-arabinofuranosidase
C7M18_RS00900	COG0395	ABC-type sugar transport system, permease component
C7M18_RS00905	COG1175	transmembrane transport
C7M18_RS00910	COG1653	transport
C7M18_RS00920	COG0647	UMP catabolic process
C7M18_RS00925	COG0235	Class ii aldolase
C7M18_RS00930	COG1069	ribulokinase activity
C7M18_RS00935	COG2160	L-arabinose isomerase activity
C7M18_RS00940	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M18_RS00945	COG1363	Peptidase, m42
C7M18_RS00955	COG3326	Membrane
C7M18_RS00970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M18_RS00975	COG1346	cytolysis
C7M18_RS00980	COG1380	Effector of murein hydrolase LrgA
C7M18_RS00985	COG3279	Response regulator of the LytR AlgR family
C7M18_RS00990	COG3275	phosphorelay sensor kinase activity
C7M18_RS01010	COG0398	Pfam SNARE associated Golgi protein
C7M18_RS01015	COG1484	DNA-dependent DNA replication
C7M18_RS01020	COG3611	Membrane attachment protein
C7M18_RS01035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M18_RS01040	COG1733	regulation of RNA biosynthetic process
C7M18_RS01045	COG2814	Major facilitator Superfamily
C7M18_RS01050	COG0656	L-ascorbic acid biosynthetic process
C7M18_RS01055	COG0237	dephospho-CoA kinase activity
C7M18_RS01060	COG1971	Probably functions as a manganese efflux pump
C7M18_RS01065	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M18_RS01070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M18_RS01070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M18_RS01075	COG5002	protein histidine kinase activity
C7M18_RS01080	COG0745	RESPONSE REGULATOR receiver
C7M18_RS01090	COG0538	isocitrate dehydrogenase activity
C7M18_RS01095	COG0372	Belongs to the citrate synthase family
C7M18_RS01100	COG0457	Tetratricopeptide repeat
C7M18_RS01105	COG5444	nuclease activity
C7M18_RS01130	COG0628	permease
C7M18_RS01135	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M18_RS01140	COG0469	pyruvate kinase activity
C7M18_RS01160	COG0281	malic enzyme
C7M18_RS01165	COG0587	DNA-directed DNA polymerase activity
C7M18_RS01185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M18_RS01195	COG4109	DRTGG domain
C7M18_RS01205	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS01220	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M18_RS01230	COG0827	DNA restriction-modification system
C7M18_RS01235	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M18_RS01240	COG3874	Sporulation protein YtfJ
C7M18_RS01250	COG1714	RDD family
C7M18_RS01255	COG0616	signal peptide processing
C7M18_RS01260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M18_RS01265	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C7M18_RS01270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M18_RS01285	COG1104	cysteine desulfurase activity
C7M18_RS01290	COG1114	Component of the transport system for branched-chain amino acids
C7M18_RS01300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M18_RS01305	COG1309	transcriptional regulator
C7M18_RS01310	COG1956	GAF domain-containing protein
C7M18_RS01315	COG2199	diguanylate cyclase activity
C7M18_RS01315	COG2203	Gaf domain
C7M18_RS01330	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS01345	COG0556	nucleotide-excision repair
C7M18_RS01365	COG1017	nitric oxide dioxygenase activity
C7M18_RS01365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M18_RS01380	COG0693	protein deglycase activity
C7M18_RS01395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M18_RS01400	COG1378	Sugar-specific transcriptional regulator TrmB
C7M18_RS01420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M18_RS01425	COG0454	-acetyltransferase
C7M18_RS01430	COG0517	IMP dehydrogenase activity
C7M18_RS01435	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M18_RS01440	COG1360	Flagellar Motor Protein
C7M18_RS01445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M18_RS01450	COG1609	Transcriptional regulator
C7M18_RS01455	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M18_RS01455	COG1605	Chorismate mutase
C7M18_RS01460	COG3118	belongs to the thioredoxin family
C7M18_RS01465	COG4980	gas vesicle protein
C7M18_RS01470	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M18_RS01480	COG1674	ftsk spoiiie
C7M18_RS01485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M18_RS01495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS01505	COG1363	Peptidase, m42
C7M18_RS01510	COG5584	Small secreted protein
C7M18_RS01515	COG0281	malic enzyme
C7M18_RS01520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS01535	COG0510	thiamine kinase activity
C7M18_RS01540	COG1597	lipid kinase activity
C7M18_RS01550	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M18_RS01555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M18_RS01560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M18_RS01565	COG2252	PERMEase
C7M18_RS01570	COG4473	ABC transporter
C7M18_RS01575	COG1131	(ABC) transporter
C7M18_RS01580	COG1349	DNA-binding transcription factor activity
C7M18_RS01585	COG1187	pseudouridine synthase activity
C7M18_RS01590	COG2244	polysaccharide biosynthetic process
C7M18_RS01595	COG2081	HI0933 family
C7M18_RS01600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M18_RS01635	COG1486	melibiose metabolic process
C7M18_RS01645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M18_RS01660	COG2202	Pas domain
C7M18_RS01660	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS01665	COG2814	Major facilitator Superfamily
C7M18_RS01670	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M18_RS01675	COG0577	efflux transmembrane transporter activity
C7M18_RS01680	COG1136	(ABC) transporter
C7M18_RS01685	COG2205	protein histidine kinase activity
C7M18_RS01690	COG0745	RESPONSE REGULATOR receiver
C7M18_RS01695	COG0577	efflux transmembrane transporter activity
C7M18_RS01700	COG1136	(ABC) transporter
C7M18_RS01720	COG1131	(ABC) transporter
C7M18_RS01725	COG1725	Transcriptional regulator
C7M18_RS01740	COG0477	Major facilitator Superfamily
C7M18_RS01745	COG1242	4 iron, 4 sulfur cluster binding
C7M18_RS01750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M18_RS01760	COG0584	glycerophosphoryl diester phosphodiesterase
C7M18_RS01770	COG2267	carboxylic ester hydrolase activity
C7M18_RS01775	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M18_RS01780	COG1113	amino acid transport
C7M18_RS01785	COG0367	asparagine synthase
C7M18_RS01805	COG1506	peptidase
C7M18_RS01810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M18_RS01815	COG1116	anion transmembrane transporter activity
C7M18_RS01820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M18_RS01825	COG0494	nUDIX hydrolase
C7M18_RS01830	COG4824	toxin secretion phage lysis holin
C7M18_RS01835	COG0783	Belongs to the Dps family
C7M18_RS01860	COG0288	reversible hydration of carbon dioxide
C7M18_RS01870	COG1271	oxidase subunit
C7M18_RS01875	COG1294	oxidase, subunit
C7M18_RS01885	COG4948	Mandelate Racemase Muconate Lactonizing
C7M18_RS01895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M18_RS01900	COG0596	Alpha beta hydrolase
C7M18_RS01910	COG1169	isochorismate synthase
C7M18_RS01915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M18_RS01920	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M18_RS02050	COG3859	Proton-coupled thiamine transporter YuaJ
C7M18_RS02055	COG2268	Band 7 protein
C7M18_RS02060	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7M18_RS02065	COG2318	DinB family
C7M18_RS02075	COG1454	alcohol dehydrogenase
C7M18_RS02085	COG1510	regulation of RNA biosynthetic process
C7M18_RS02095	COG0569	domain protein
C7M18_RS02100	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M18_RS02105	COG1017	nitric oxide dioxygenase activity
C7M18_RS02105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M18_RS02130	COG0628	permease
C7M18_RS02135	COG0673	inositol 2-dehydrogenase activity
C7M18_RS02140	COG0693	protein deglycase activity
C7M18_RS02145	COG0840	transmembrane signaling receptor activity
C7M18_RS02150	COG0840	transmembrane signaling receptor activity
C7M18_RS02155	COG0840	transmembrane signaling receptor activity
C7M18_RS02160	COG0840	transmembrane signaling receptor activity
C7M18_RS02175	COG2070	2-Nitropropane dioxygenase
C7M18_RS02180	COG0432	Pfam Uncharacterised protein family UPF0047
C7M18_RS02185	COG0366	Alpha amylase catalytic
C7M18_RS02190	COG1253	flavin adenine dinucleotide binding
C7M18_RS02195	COG2738	Putative neutral zinc metallopeptidase
C7M18_RS02210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M18_RS02235	COG1335	isochorismatase
C7M18_RS02240	COG1979	alcohol dehydrogenase
C7M18_RS02245	COG1979	alcohol dehydrogenase
C7M18_RS02250	COG2155	Conserved Protein
C7M18_RS02255	COG1098	S1 RNA binding domain
C7M18_RS02260	COG0436	Aminotransferase
C7M18_RS02265	COG1522	sequence-specific DNA binding
C7M18_RS02270	COG2267	carboxylic ester hydrolase activity
C7M18_RS02285	COG2205	protein histidine kinase activity
C7M18_RS02295	COG5018	Exonuclease
C7M18_RS02300	COG2814	Major facilitator Superfamily
C7M18_RS02305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M18_RS02310	COG3011	Protein conserved in bacteria
C7M18_RS02320	COG3290	protein histidine kinase activity
C7M18_RS02325	COG4565	transcriptional regulatory protein
C7M18_RS02355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M18_RS02355	COG2111	Na H antiporter
C7M18_RS02360	COG2111	Na H antiporter
C7M18_RS02365	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M18_RS02370	COG0651	ATP synthesis coupled electron transport
C7M18_RS02375	COG1863	multisubunit Na H antiporter MnhE subunit
C7M18_RS02380	COG2212	antiporter activity
C7M18_RS02385	COG1320	monovalent cation:proton antiporter activity
C7M18_RS02390	COG2050	protein possibly involved in aromatic compounds catabolism
C7M18_RS02395	COG2197	response regulator
C7M18_RS02400	COG4585	Histidine kinase
C7M18_RS02405	COG0142	geranyltranstransferase activity
C7M18_RS02420	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M18_RS02425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M18_RS02430	COG1335	isochorismatase
C7M18_RS02435	COG5506	Protein of unknown function (DUF1694)
C7M18_RS02450	COG0628	permease
C7M18_RS02460	COG1418	mRNA catabolic process
C7M18_RS02465	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS02475	COG1511	domain protein
C7M18_RS02480	COG1674	ftsk spoiiie
C7M18_RS02480	COG0433	COG0433 Predicted ATPase
C7M18_RS02485	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M18_RS02490	COG5417	Belongs to the EsaB family
C7M18_RS02495	COG4842	Belongs to the WXG100 family
C7M18_RS02500	COG2508	Transcriptional regulator
C7M18_RS02500	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M18_RS02505	COG0686	Belongs to the AlaDH PNT family
C7M18_RS02510	COG5634	Uncharacterized conserved protein (DUF2278)
C7M18_RS02515	COG3251	PFAM MbtH domain protein
C7M18_RS02520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS02525	COG1535	isochorismatase
C7M18_RS02525	COG3433	isochorismatase activity
C7M18_RS02530	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M18_RS02535	COG1169	isochorismate synthase
C7M18_RS02540	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS02545	COG2819	hydrolase of the alpha beta superfamily
C7M18_RS02550	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M18_RS02555	COG1268	BioY protein
C7M18_RS02560	COG2056	Na+-H+ antiporter family
C7M18_RS02570	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M18_RS02575	COG3584	3D domain protein
C7M18_RS02590	COG1252	NADH dehydrogenase
C7M18_RS02615	COG1131	(ABC) transporter
C7M18_RS02635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS02640	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M18_RS02645	COG0316	Belongs to the HesB IscA family
C7M18_RS02655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M18_RS02665	COG1252	NADH dehydrogenase
C7M18_RS02670	COG4837	Protein of unknown function (DUF1462)
C7M18_RS02675	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M18_RS02680	COG0823	Involved in the tonB-independent uptake of proteins
C7M18_RS02680	COG1506	peptidase
C7M18_RS02680	COG4946	Tricorn protease homolog
C7M18_RS02690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M18_RS02695	COG0460	homoserine dehydrogenase
C7M18_RS02700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M18_RS02705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M18_RS02710	COG0647	UMP catabolic process
C7M18_RS02715	COG2445	Protein of unknown function DUF86
C7M18_RS02720	COG4470	Protein conserved in bacteria
C7M18_RS02730	COG0739	heme binding
C7M18_RS02740	COG0737	Belongs to the 5'-nucleotidase family
C7M18_RS02745	COG0730	response to heat
C7M18_RS02750	COG1801	Protein of unknown function DUF72
C7M18_RS02765	COG2508	Transcriptional regulator
C7M18_RS02770	COG0457	Tetratricopeptide repeat
C7M18_RS02780	COG2814	Major facilitator Superfamily
C7M18_RS02785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M18_RS02790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M18_RS02795	COG2356	endonuclease I
C7M18_RS02800	COG3842	ATPase activity
C7M18_RS02805	COG2188	Transcriptional regulator
C7M18_RS02810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M18_RS02815	COG0395	ABC-type sugar transport system, permease component
C7M18_RS02820	COG1175	transmembrane transport
C7M18_RS02825	COG1653	transport
C7M18_RS02830	COG2222	sugar isomerase
C7M18_RS02835	COG0789	Transcriptional regulator
C7M18_RS02860	COG0322	excinuclease ABC activity
C7M18_RS02865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M18_RS02885	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS02890	COG0719	Fe-S assembly protein
C7M18_RS02895	COG0822	iron-sulfur transferase activity
C7M18_RS02900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M18_RS02905	COG0719	Fe-S assembly protein
C7M18_RS02910	COG0396	ATPase activity
C7M18_RS02920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M18_RS02925	COG1464	Belongs to the NlpA lipoprotein family
C7M18_RS02930	COG2011	ABC-type metal ion transport system permease component
C7M18_RS02935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M18_RS02945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS02950	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M18_RS02965	COG1393	Belongs to the ArsC family
C7M18_RS02970	COG1960	acyl-CoA dehydrogenase activity
C7M18_RS02975	COG0183	Belongs to the thiolase family
C7M18_RS02980	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M18_RS02980	COG1024	Enoyl-CoA hydratase
C7M18_RS03000	COG5577	PFAM Coat F domain
C7M18_RS03005	COG1846	Transcriptional regulator
C7M18_RS03010	COG0477	Major facilitator Superfamily
C7M18_RS03015	COG0583	DNA-binding transcription factor activity
C7M18_RS03035	COG1120	ATPase activity
C7M18_RS03050	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS03055	COG0783	Belongs to the Dps family
C7M18_RS03060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M18_RS03065	COG0745	RESPONSE REGULATOR receiver
C7M18_RS03070	COG2770	Histidine kinase
C7M18_RS03070	COG2205	protein histidine kinase activity
C7M18_RS03080	COG1309	transcriptional regulator
C7M18_RS03085	COG0114	fumarate hydratase activity
C7M18_RS03095	COG0697	spore germination
C7M18_RS03100	COG0814	amino acid
C7M18_RS03110	COG2197	response regulator
C7M18_RS03115	COG4585	Histidine kinase
C7M18_RS03120	COG4758	membrane
C7M18_RS03125	COG3595	metallopeptidase activity
C7M18_RS03130	COG1842	Phage shock protein A
C7M18_RS03135	COG4758	membrane
C7M18_RS03140	COG2814	Major facilitator Superfamily
C7M18_RS03145	COG2096	Adenosyltransferase
C7M18_RS03150	COG1120	ATPase activity
C7M18_RS03155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS03160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M18_RS03165	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS03170	COG3386	PFAM SMP-30 Gluconolaconase
C7M18_RS03175	COG2205	protein histidine kinase activity
C7M18_RS03180	COG0745	RESPONSE REGULATOR receiver
C7M18_RS03190	COG1191	sigma factor activity
C7M18_RS03200	COG2140	Oxalate decarboxylase
C7M18_RS03215	COG1120	ATPase activity
C7M18_RS03220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS03225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS03230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M18_RS03235	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M18_RS03240	COG0531	amino acid
C7M18_RS03250	COG1988	membrane-bound metal-dependent
C7M18_RS03255	COG1368	sulfuric ester hydrolase activity
C7M18_RS03260	COG1910	domain protein
C7M18_RS03265	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M18_RS03270	COG4149	molybdate abc transporter
C7M18_RS03275	COG2197	response regulator
C7M18_RS03280	COG3850	Histidine kinase
C7M18_RS03285	COG1131	(ABC) transporter
C7M18_RS03295	COG0842	Transport permease protein
C7M18_RS03300	COG0656	L-ascorbic acid biosynthetic process
C7M18_RS03320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M18_RS03325	COG3973	AAA domain
C7M18_RS03330	COG2860	membrane
C7M18_RS03340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M18_RS03345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M18_RS03350	COG2217	Heavy metal translocating P-type atpase
C7M18_RS03355	COG2217	Heavy metal translocating P-type atpase
C7M18_RS03360	COG2608	mercury ion transmembrane transporter activity
C7M18_RS03365	COG1937	Protein conserved in bacteria
C7M18_RS03370	COG0673	inositol 2-dehydrogenase activity
C7M18_RS03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M18_RS03385	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7M18_RS03390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M18_RS03395	COG1126	abc transporter atp-binding protein
C7M18_RS03400	COG0765	amino acid transport
C7M18_RS03405	COG0765	amino acid transport
C7M18_RS03410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS03415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS03420	COG0454	-acetyltransferase
C7M18_RS03425	COG0583	DNA-binding transcription factor activity
C7M18_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS03435	COG2732	(Barnase) inhibitor
C7M18_RS03440	COG2732	(Barnase) inhibitor
C7M18_RS03455	COG0557	exoribonuclease II activity
C7M18_RS03460	COG1647	Serine aminopeptidase, S33
C7M18_RS03465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M18_RS03470	COG1476	TRANSCRIPTIONal
C7M18_RS03475	COG1396	sequence-specific DNA binding
C7M18_RS03480	COG1396	sequence-specific DNA binding
C7M18_RS03485	COG1733	regulation of RNA biosynthetic process
C7M18_RS03515	COG1174	glycine betaine transport
C7M18_RS03520	COG1732	Glycine betaine
C7M18_RS03525	COG1174	glycine betaine transport
C7M18_RS03530	COG1125	glycine betaine transport
C7M18_RS03530	COG0517	IMP dehydrogenase activity
C7M18_RS03535	COG1510	regulation of RNA biosynthetic process
C7M18_RS03540	COG1174	glycine betaine transport
C7M18_RS03545	COG1732	Glycine betaine
C7M18_RS03550	COG1174	glycine betaine transport
C7M18_RS03555	COG0517	IMP dehydrogenase activity
C7M18_RS03555	COG1125	glycine betaine transport
C7M18_RS03560	COG1510	regulation of RNA biosynthetic process
C7M18_RS03565	COG2095	MarC family integral membrane protein
C7M18_RS03570	COG3064	Membrane
C7M18_RS03575	COG4640	response to antibiotic
C7M18_RS03580	COG0456	acetyltransferase
C7M18_RS03600	COG0126	phosphoglycerate kinase activity
C7M18_RS03610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M18_RS03615	COG2390	Transcriptional regulator
C7M18_RS03620	COG2814	Major facilitator Superfamily
C7M18_RS03625	COG1609	Transcriptional regulator
C7M18_RS03630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M18_RS03635	COG0583	DNA-binding transcription factor activity
C7M18_RS03640	COG0697	spore germination
C7M18_RS03645	COG1113	amino acid transport
C7M18_RS03650	COG1737	Transcriptional regulator
C7M18_RS03655	COG1070	Carbohydrate kinase
C7M18_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS03685	COG2186	Transcriptional regulator
C7M18_RS03690	COG1620	l-lactate permease
C7M18_RS03695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M18_RS03705	COG5039	Polysaccharide pyruvyl transferase
C7M18_RS03710	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M18_RS03715	COG0110	maltose O-acetyltransferase activity
C7M18_RS03720	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M18_RS03725	COG2244	polysaccharide biosynthetic process
C7M18_RS03730	COG1216	Glycosyl transferase, family 2
C7M18_RS03735	COG5039	Polysaccharide pyruvyl transferase
C7M18_RS03740	COG1216	Glycosyl transferase, family 2
C7M18_RS03750	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS03755	COG1215	transferase activity, transferring glycosyl groups
C7M18_RS03760	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS03765	COG1086	Polysaccharide biosynthesis protein
C7M18_RS03770	COG0489	protein tyrosine kinase activity
C7M18_RS03775	COG3944	biosynthesis protein
C7M18_RS03780	COG1396	sequence-specific DNA binding
C7M18_RS03785	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M18_RS03795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M18_RS03800	COG2364	Membrane
C7M18_RS03805	COG0456	acetyltransferase
C7M18_RS03810	COG3479	Phenolic acid decarboxylase
C7M18_RS03850	COG2223	nitrite transmembrane transporter activity
C7M18_RS03855	COG1609	Transcriptional regulator
C7M18_RS03865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M18_RS03870	COG0366	Alpha amylase catalytic
C7M18_RS03875	COG1554	hydrolase, family 65, central catalytic
C7M18_RS03880	COG5521	maltodextrose utilization protein MalA
C7M18_RS03885	COG3833	ABC-type maltose transport systems, permease component
C7M18_RS03890	COG1175	transmembrane transport
C7M18_RS03895	COG2182	Extracellular solute-binding protein
C7M18_RS03900	COG0366	Alpha amylase catalytic
C7M18_RS03905	COG1609	Transcriptional regulator
C7M18_RS03910	COG1611	Belongs to the LOG family
C7M18_RS03915	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M18_RS03920	COG0659	secondary active sulfate transmembrane transporter activity
C7M18_RS03925	COG0288	reversible hydration of carbon dioxide
C7M18_RS03930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M18_RS03935	COG4290	ribonuclease
C7M18_RS03940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M18_RS03945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS03955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M18_RS03965	COG1051	belongs to the nudix hydrolase family
C7M18_RS03970	COG0492	ferredoxin-NADP+ reductase activity
C7M18_RS03975	COG0791	NLP P60 protein
C7M18_RS03975	COG3883	PFAM NLP P60 protein
C7M18_RS03980	COG0457	Tetratricopeptide repeat
C7M18_RS03985	COG5002	protein histidine kinase activity
C7M18_RS03990	COG0745	RESPONSE REGULATOR receiver
C7M18_RS04000	COG1132	(ABC) transporter
C7M18_RS04005	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M18_RS04005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M18_RS04030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M18_RS04045	COG4990	cell redox homeostasis
C7M18_RS04050	COG0110	maltose O-acetyltransferase activity
C7M18_RS04070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M18_RS04085	COG1309	transcriptional regulator
C7M18_RS04090	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M18_RS04095	COG1950	PFAM Membrane protein of
C7M18_RS04100	COG1983	PspC domain protein
C7M18_RS04105	COG3595	metallopeptidase activity
C7M18_RS04120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M18_RS04130	COG4897	Protein conserved in bacteria
C7M18_RS04135	COG3848	Pyruvate phosphate dikinase
C7M18_RS04135	COG0574	Belongs to the PEP-utilizing enzyme family
C7M18_RS04140	COG1309	transcriptional regulator
C7M18_RS04145	COG2814	Major facilitator Superfamily
C7M18_RS04180	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS04190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M18_RS04200	COG0793	Belongs to the peptidase S41A family
C7M18_RS04200	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS04205	COG3420	alginic acid biosynthetic process
C7M18_RS04210	COG2177	Part of the ABC transporter FtsEX involved in
C7M18_RS04215	COG2884	Cell division ATP-binding protein ftsE
C7M18_RS04220	COG2010	Cytochrome c
C7M18_RS04225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS04240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M18_RS04255	COG1516	flagellar protein fliS
C7M18_RS04260	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M18_RS04265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M18_RS04285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M18_RS04290	COG4786	Flagellar basal body rod
C7M18_RS04290	COG1256	bacterial-type flagellum assembly
C7M18_RS04295	COG3418	PFAM FlgN family protein
C7M18_RS04300	COG2747	anti-sigma28 factor FlgM
C7M18_RS04310	COG1040	competence protein
C7M18_RS04320	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M18_RS04325	COG1307	EDD domain protein, DegV family
C7M18_RS04330	COG2197	response regulator
C7M18_RS04335	COG4585	Histidine kinase
C7M18_RS04340	COG1739	Uncharacterized protein family UPF0029
C7M18_RS04345	COG1316	TRANSCRIPTIONal
C7M18_RS04350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M18_RS04355	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS04360	COG1215	transferase activity, transferring glycosyl groups
C7M18_RS04365	COG3206	protein involved in exopolysaccharide biosynthesis
C7M18_RS04370	COG3307	-O-antigen
C7M18_RS04375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M18_RS04380	COG0297	glycogen (starch) synthase activity
C7M18_RS04380	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS04385	COG2244	polysaccharide biosynthetic process
C7M18_RS04395	COG2247	cell wall binding repeat
C7M18_RS04395	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS04400	COG2385	sporulation resulting in formation of a cellular spore
C7M18_RS04400	COG2247	cell wall binding repeat
C7M18_RS04410	COG1316	TRANSCRIPTIONal
C7M18_RS04415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M18_RS04420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M18_RS04425	COG1134	teichoic acid transport
C7M18_RS04430	COG1682	transport, permease protein
C7M18_RS04435	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M18_RS04440	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS04445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M18_RS04450	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M18_RS04455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M18_RS04460	COG4193	domain, Protein
C7M18_RS04465	COG1482	cell wall glycoprotein biosynthetic process
C7M18_RS04470	COG0697	spore germination
C7M18_RS04475	COG0814	amino acid
C7M18_RS04485	COG1215	transferase activity, transferring glycosyl groups
C7M18_RS04490	COG2814	Major facilitator Superfamily
C7M18_RS04495	COG1316	TRANSCRIPTIONal
C7M18_RS04500	COG0561	phosphatase activity
C7M18_RS04505	COG2433	Pfam Transposase IS66
C7M18_RS04510	COG0791	NLP P60 protein
C7M18_RS04520	COG2843	Capsule synthesis protein
C7M18_RS04530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M18_RS04535	COG0697	spore germination
C7M18_RS04540	COG0814	amino acid
C7M18_RS04550	COG1609	Transcriptional regulator
C7M18_RS04555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M18_RS04565	COG1129	ABC transporter
C7M18_RS04570	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M18_RS04575	COG1879	ABC-type sugar transport system periplasmic component
C7M18_RS04580	COG3103	Sh3 type 3 domain protein
C7M18_RS04585	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M18_RS04590	COG3527	Alpha-acetolactate decarboxylase
C7M18_RS04595	COG0028	Belongs to the TPP enzyme family
C7M18_RS04600	COG0583	DNA-binding transcription factor activity
C7M18_RS04605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M18_RS04620	COG5337	Spore coat protein CotH
C7M18_RS04630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M18_RS04640	COG0405	Gamma-glutamyltransferase
C7M18_RS04645	COG1522	sequence-specific DNA binding
C7M18_RS04650	COG2059	Chromate
C7M18_RS04655	COG2059	Chromate
C7M18_RS04665	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M18_RS04670	COG0583	DNA-binding transcription factor activity
C7M18_RS04690	COG5444	nuclease activity
C7M18_RS04705	COG3878	Protein conserved in bacteria
C7M18_RS04710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M18_RS04715	COG4464	protein tyrosine phosphatase activity
C7M18_RS04720	COG0489	protein tyrosine kinase activity
C7M18_RS04725	COG3944	biosynthesis protein
C7M18_RS04735	COG4715	Zinc finger, swim domain protein
C7M18_RS04740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M18_RS04745	COG0561	phosphatase activity
C7M18_RS04750	COG1349	DNA-binding transcription factor activity
C7M18_RS04755	COG0629	single-stranded DNA binding
C7M18_RS04780	COG0457	Tetratricopeptide repeat
C7M18_RS04785	COG4786	Flagellar basal body rod
C7M18_RS04790	COG4786	Flagellar basal body rod
C7M18_RS04795	COG1077	Cell shape determining protein MreB Mrl
C7M18_RS04800	COG1609	Transcriptional regulator
C7M18_RS04805	COG1846	Transcriptional regulator
C7M18_RS04810	COG2814	Major facilitator Superfamily
C7M18_RS04815	COG1953	Uracil, thiamine, allantoin
C7M18_RS04820	COG0477	Major facilitator Superfamily
C7M18_RS04825	COG1335	isochorismatase
C7M18_RS04830	COG0004	ammonium transporteR
C7M18_RS04835	COG0347	Belongs to the P(II) protein family
C7M18_RS04840	COG0772	Belongs to the SEDS family
C7M18_RS04845	COG0671	phosphoesterase, PA-phosphatase related
C7M18_RS04855	COG0739	heme binding
C7M18_RS04860	COG1247	-acetyltransferase
C7M18_RS04875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M18_RS04885	COG0726	polysaccharide deacetylase
C7M18_RS04890	COG1959	2 iron, 2 sulfur cluster binding
C7M18_RS04905	COG0831	urea catabolic process
C7M18_RS04910	COG3237	CsbD-like
C7M18_RS04915	COG1994	Peptidase M50
C7M18_RS04920	COG0457	Tetratricopeptide repeat
C7M18_RS04930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M18_RS04935	COG2304	oxidoreductase activity
C7M18_RS04940	COG2304	oxidoreductase activity
C7M18_RS04945	COG2385	sporulation resulting in formation of a cellular spore
C7M18_RS04950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M18_RS04960	COG4836	Membrane
C7M18_RS05000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M18_RS05030	COG0698	ribose 5-phosphate isomerase
C7M18_RS05035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M18_RS05045	COG0009	L-threonylcarbamoyladenylate synthase
C7M18_RS05050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M18_RS05070	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M18_RS05075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M18_RS05080	COG0346	lactoylglutathione lyase activity
C7M18_RS05085	COG0789	Transcriptional regulator
C7M18_RS05090	COG0679	Auxin Efflux Carrier
C7M18_RS05095	COG0281	malic enzyme
C7M18_RS05105	COG0254	rRNA binding
C7M18_RS05110	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M18_RS05115	COG1494	fructose-1,6-bisphosphatase
C7M18_RS05120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M18_RS05130	COG0191	fructose-bisphosphate aldolase activity
C7M18_RS05135	COG2204	response regulator
C7M18_RS05140	COG4821	SIS domain
C7M18_RS05155	COG0247	lactate metabolic process
C7M18_RS05155	COG2181	nitrate reductase activity
C7M18_RS05160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M18_RS05175	COG1132	(ABC) transporter
C7M18_RS05180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M18_RS05190	COG2181	nitrate reductase activity
C7M18_RS05195	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M18_RS05200	COG1140	nitrate reductase beta subunit
C7M18_RS05205	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M18_RS05210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M18_RS05220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M18_RS05225	COG2223	nitrite transmembrane transporter activity
C7M18_RS05235	COG4506	Protein conserved in bacteria
C7M18_RS05240	COG0457	Tetratricopeptide repeat
C7M18_RS05285	COG0010	Belongs to the arginase family
C7M18_RS05290	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M18_RS05295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M18_RS05310	COG1994	Peptidase M50
C7M18_RS05315	COG1942	4-Oxalocrotonate Tautomerase
C7M18_RS05320	COG1846	Transcriptional regulator
C7M18_RS05330	COG0531	amino acid
C7M18_RS05335	COG3465	dGTPase activity
C7M18_RS05340	COG1078	dGTPase activity
C7M18_RS05355	COG1695	Transcriptional regulator
C7M18_RS05365	COG1131	(ABC) transporter
C7M18_RS05370	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M18_RS05400	COG0583	DNA-binding transcription factor activity
C7M18_RS05405	COG2855	membrane
C7M18_RS05410	COG0280	phosphate acetyltransferase
C7M18_RS05420	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS05425	COG0436	Aminotransferase
C7M18_RS05455	COG2814	Major facilitator Superfamily
C7M18_RS05460	COG2814	Major facilitator Superfamily
C7M18_RS05465	COG0833	amino acid
C7M18_RS05470	COG4187	Peptidase family M20/M25/M40
C7M18_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS05480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M18_RS05485	COG2205	protein histidine kinase activity
C7M18_RS05490	COG0745	RESPONSE REGULATOR receiver
C7M18_RS05505	COG1131	(ABC) transporter
C7M18_RS05510	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C7M18_RS05515	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7M18_RS05520	COG1088	dTDP-glucose 4,6-dehydratase activity
C7M18_RS05525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7M18_RS05530	COG3980	spore coat polysaccharide biosynthesis protein
C7M18_RS05535	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7M18_RS05540	COG2089	acid synthase
C7M18_RS05545	COG0456	acetyltransferase
C7M18_RS05550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M18_RS05555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M18_RS05560	COG0463	Glycosyl transferase, family 2
C7M18_RS05570	COG2363	Small membrane protein
C7M18_RS05575	COG2233	PERMEase
C7M18_RS05590	COG1216	Glycosyl transferase, family 2
C7M18_RS05605	COG1695	Transcriptional regulator
C7M18_RS05610	COG0351	phosphomethylpyrimidine kinase
C7M18_RS05620	COG1621	beta-fructofuranosidase activity
C7M18_RS05625	COG1263	PTS System
C7M18_RS05625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS05630	COG3711	transcriptional antiterminator
C7M18_RS05640	COG1404	Belongs to the peptidase S8 family
C7M18_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M18_RS05650	COG0778	Nitroreductase
C7M18_RS05655	COG1136	(ABC) transporter
C7M18_RS05675	COG0772	Belongs to the SEDS family
C7M18_RS05680	COG0454	-acetyltransferase
C7M18_RS05700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M18_RS05705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M18_RS05710	COG2261	transglycosylase associated protein
C7M18_RS05715	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M18_RS05720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M18_RS05725	COG2246	polysaccharide biosynthetic process
C7M18_RS05730	COG1309	transcriptional regulator
C7M18_RS05750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M18_RS05755	COG2837	iron assimilation
C7M18_RS05760	COG2822	iron ion transport
C7M18_RS05775	COG0583	DNA-binding transcription factor activity
C7M18_RS05785	COG1346	cytolysis
C7M18_RS05790	COG4895	conserved protein (DUF2196)
C7M18_RS05795	COG0789	Transcriptional regulator
C7M18_RS05800	COG5504	Zn-dependent protease
C7M18_RS05805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M18_RS05810	COG0346	lactoylglutathione lyase activity
C7M18_RS05815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS05820	COG1404	Belongs to the peptidase S8 family
C7M18_RS05825	COG1442	glycosyl transferase family 8
C7M18_RS05830	COG1846	Transcriptional regulator
C7M18_RS05835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M18_RS05840	COG2357	RelA SpoT domain protein
C7M18_RS05845	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M18_RS05860	COG1696	Membrane protein involved in D-alanine export
C7M18_RS05870	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M18_RS05875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS05880	COG1486	melibiose metabolic process
C7M18_RS05885	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M18_RS05890	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS05895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS05900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS05900	COG3711	transcriptional antiterminator
C7M18_RS05910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS05925	COG0640	Transcriptional regulator
C7M18_RS05930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M18_RS05935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS05940	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M18_RS05945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS05950	COG2723	6-phospho-beta-galactosidase activity
C7M18_RS05955	COG1940	carbohydrate kinase activity
C7M18_RS05960	COG1482	cell wall glycoprotein biosynthetic process
C7M18_RS05970	COG0753	catalase activity
C7M18_RS05975	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M18_RS05980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M18_RS05985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M18_RS05990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M18_RS05995	COG4988	ABC transporter
C7M18_RS06000	COG1294	oxidase, subunit
C7M18_RS06005	COG1271	oxidase subunit
C7M18_RS06010	COG3493	citrate carrier protein
C7M18_RS06015	COG0726	polysaccharide deacetylase
C7M18_RS06020	COG3842	ATPase activity
C7M18_RS06025	COG2508	Transcriptional regulator
C7M18_RS06030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS06040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M18_RS06050	COG4894	glucomannan catabolic process
C7M18_RS06055	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M18_RS06060	COG0500	methyltransferase
C7M18_RS06065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M18_RS06085	COG0753	catalase activity
C7M18_RS06085	COG0693	protein deglycase activity
C7M18_RS06090	COG2851	Citrate transporter
C7M18_RS06095	COG2273	Hydrolase Family 16
C7M18_RS06100	COG3711	transcriptional antiterminator
C7M18_RS06105	COG2270	Major facilitator Superfamily
C7M18_RS06110	COG0513	Belongs to the DEAD box helicase family
C7M18_RS06195	COG0697	spore germination
C7M18_RS06200	COG0589	response to stress
C7M18_RS06205	COG2723	6-phospho-beta-galactosidase activity
C7M18_RS06210	COG2190	(PTS) system
C7M18_RS06210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS06210	COG1263	PTS System
C7M18_RS06225	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M18_RS06250	COG0010	Belongs to the arginase family
C7M18_RS06255	COG0833	amino acid
C7M18_RS06260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M18_RS06265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M18_RS06275	COG2390	Transcriptional regulator
C7M18_RS06280	COG0561	phosphatase activity
C7M18_RS06310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M18_RS06315	COG5294	Protein conserved in bacteria
C7M18_RS06320	COG0577	efflux transmembrane transporter activity
C7M18_RS06325	COG1136	(ABC) transporter
C7M18_RS06335	COG0745	RESPONSE REGULATOR receiver
C7M18_RS06340	COG2205	protein histidine kinase activity
C7M18_RS06345	COG0745	RESPONSE REGULATOR receiver
C7M18_RS06375	COG1082	Xylose isomerase domain protein TIM barrel
C7M18_RS06385	COG2814	Major facilitator Superfamily
C7M18_RS06415	COG1349	DNA-binding transcription factor activity
C7M18_RS06420	COG0667	Aldo Keto reductase
C7M18_RS06425	COG2814	Major facilitator Superfamily
C7M18_RS06445	COG2197	response regulator
C7M18_RS06450	COG4585	Histidine kinase
C7M18_RS06455	COG3239	Fatty acid desaturase
C7M18_RS06460	COG1309	transcriptional regulator
C7M18_RS06465	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS06470	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7M18_RS06480	COG0640	Transcriptional regulator
C7M18_RS06485	COG2814	Major facilitator Superfamily
C7M18_RS06490	COG1714	RDD family
C7M18_RS06500	COG0450	alkyl hydroperoxide reductase
C7M18_RS06505	COG3634	alkyl hydroperoxide reductase activity
C7M18_RS06510	COG1113	amino acid transport
C7M18_RS06520	COG2080	2 iron, 2 sulfur cluster binding
C7M18_RS06535	COG2068	MobA-Related Protein
C7M18_RS06540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C7M18_RS06615	COG2003	Belongs to the UPF0758 family
C7M18_RS06645	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C7M18_RS06650	COG0667	Aldo Keto reductase
C7M18_RS06655	COG0456	acetyltransferase
C7M18_RS06660	COG0457	Tetratricopeptide repeat
C7M18_RS06665	COG0010	Belongs to the arginase family
C7M18_RS06670	COG0833	amino acid
C7M18_RS06675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M18_RS06680	COG5658	integral membrane protein
C7M18_RS06685	COG0640	Transcriptional regulator
C7M18_RS06690	COG3829	transcription factor binding
C7M18_RS06700	COG0488	(ABC) transporter
C7M18_RS06715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M18_RS06720	COG3850	Histidine kinase
C7M18_RS06720	COG5002	protein histidine kinase activity
C7M18_RS06735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M18_RS06740	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M18_RS06745	COG4853	Protein conserved in bacteria
C7M18_RS06750	COG4863	YycH protein
C7M18_RS06755	COG5002	protein histidine kinase activity
C7M18_RS06760	COG0745	RESPONSE REGULATOR receiver
C7M18_RS06790	COG0346	lactoylglutathione lyase activity
C7M18_RS06795	COG0305	Participates in initiation and elongation during chromosome replication
C7M18_RS06810	COG3093	addiction module antidote protein HigA
C7M18_RS06815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M18_RS06820	COG0297	glycogen (starch) synthase activity
C7M18_RS06830	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7M18_RS06835	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS06845	COG2112	serine threonine protein kinase
C7M18_RS06855	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M18_RS06860	COG4241	membrane
C7M18_RS06870	COG5577	PFAM Coat F domain
C7M18_RS06875	COG1733	regulation of RNA biosynthetic process
C7M18_RS06885	COG0697	spore germination
C7M18_RS06890	COG1621	beta-fructofuranosidase activity
C7M18_RS06895	COG1621	beta-fructofuranosidase activity
C7M18_RS06900	COG1802	Transcriptional regulator
C7M18_RS06905	COG2318	DinB family
C7M18_RS06910	COG2211	Major facilitator Superfamily
C7M18_RS06915	COG0697	spore germination
C7M18_RS06920	COG0789	Transcriptional regulator
C7M18_RS06925	COG0583	DNA-binding transcription factor activity
C7M18_RS06935	COG2814	Major facilitator Superfamily
C7M18_RS06940	COG0583	DNA-binding transcription factor activity
C7M18_RS06950	COG0778	Nitroreductase
C7M18_RS06955	COG1846	Transcriptional regulator
C7M18_RS06960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS06965	COG1846	Transcriptional regulator
C7M18_RS06970	COG2153	protein acetylation
C7M18_RS06980	COG0546	phosphoglycolate phosphatase activity
C7M18_RS07010	COG1404	Belongs to the peptidase S8 family
C7M18_RS07020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS07025	COG0697	spore germination
C7M18_RS07030	COG1078	dGTPase activity
C7M18_RS07040	COG1331	Highly conserved protein containing a thioredoxin domain
C7M18_RS07045	COG1266	CAAX protease self-immunity
C7M18_RS07050	COG0477	Major facilitator Superfamily
C7M18_RS07050	COG2814	Major facilitator Superfamily
C7M18_RS07055	COG0346	lactoylglutathione lyase activity
C7M18_RS07060	COG1609	Transcriptional regulator
C7M18_RS07065	COG0708	Exodeoxyribonuclease III
C7M18_RS07070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M18_RS07075	COG2169	Transcriptional regulator
C7M18_RS07085	COG0629	single-stranded DNA binding
C7M18_RS07095	COG0012	GTP binding
C7M18_RS07100	COG0243	molybdopterin cofactor binding
C7M18_RS07105	COG4481	Protein conserved in bacteria
C7M18_RS07110	COG3949	Membrane
C7M18_RS07125	COG1475	DNA binding
C7M18_RS07130	COG1192	Involved in chromosome partitioning
C7M18_RS07155	COG1847	R3H domain protein
C7M18_RS07160	COG0706	membrane insertase activity
C7M18_RS07170	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7M18_RS07180	COG0592	DNA-directed DNA polymerase activity
C7M18_RS07185	COG2501	S4 domain
C7M18_RS07200	COG0187	DNA topoisomerase II activity
C7M18_RS07205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M18_RS07240	COG0516	GMP reductase activity
C7M18_RS07240	COG0517	IMP dehydrogenase activity
C7M18_RS07245	COG1686	Belongs to the peptidase S11 family
C7M18_RS07265	COG1929	Belongs to the glycerate kinase type-1 family
C7M18_RS07275	COG1428	Deoxynucleoside kinase
C7M18_RS07280	COG1428	Deoxynucleoside kinase
C7M18_RS07285	COG1388	LysM domain
C7M18_RS07285	COG3858	chitin binding
C7M18_RS07290	COG1335	isochorismatase
C7M18_RS07295	COG0590	tRNA wobble adenosine to inosine editing
C7M18_RS07305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M18_RS07310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M18_RS07360	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M18_RS07365	COG3853	Toxic anion resistance protein (TelA)
C7M18_RS07370	COG1982	Orn Lys Arg decarboxylase major
C7M18_RS07380	COG3870	Protein conserved in bacteria
C7M18_RS07385	COG1728	Protein conserved in bacteria
C7M18_RS07390	COG0470	DNA polymerase III
C7M18_RS07395	COG1774	PSP1 C-terminal conserved region
C7M18_RS07405	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M18_RS07415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M18_RS07420	COG2002	toxin-antitoxin pair type II binding
C7M18_RS07425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M18_RS07425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M18_RS07430	COG0084	hydrolase, TatD family'
C7M18_RS07435	COG3584	3D domain protein
C7M18_RS07435	COG3583	domain protein
C7M18_RS07440	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M18_RS07445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M18_RS07455	COG4466	Protein conserved in bacteria
C7M18_RS07470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M18_RS07475	COG0251	oxidation-reduction process
C7M18_RS07490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M18_RS07510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M18_RS07515	COG2002	toxin-antitoxin pair type II binding
C7M18_RS07520	COG2244	polysaccharide biosynthetic process
C7M18_RS07525	COG3956	TIGRFAM MazG family protein
C7M18_RS07530	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M18_RS07545	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M18_RS07550	COG1098	S1 RNA binding domain
C7M18_RS07565	COG2208	phosphoserine phosphatase activity
C7M18_RS07570	COG2304	oxidoreductase activity
C7M18_RS07575	COG0515	serine threonine protein kinase
C7M18_RS07580	COG0037	tRNA processing
C7M18_RS07590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M18_RS07605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M18_RS07610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M18_RS07615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M18_RS07620	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M18_RS07625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS07630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M18_RS07635	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M18_RS07640	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M18_RS07645	COG1396	sequence-specific DNA binding
C7M18_RS07650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M18_RS07655	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M18_RS07735	COG4463	regulation of RNA biosynthetic process
C7M18_RS07740	COG3880	PFAM UvrB UvrC protein
C7M18_RS07750	COG0542	response to heat
C7M18_RS07755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M18_RS07760	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M18_RS07765	COG4956	integral membrane protein (PIN domain superfamily)
C7M18_RS07785	COG1045	serine acetyltransferase
C7M18_RS07795	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M18_RS07800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M18_RS07805	COG3688	RNA-binding protein containing a PIN domain
C7M18_RS07810	COG1595	DNA-templated transcription, initiation
C7M18_RS07815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M18_RS07820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M18_RS07825	COG0250	Participates in transcription elongation, termination and antitermination
C7M18_RS07830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M18_RS07845	COG0222	ribosome binding
C7M18_RS07850	COG2813	Specifically methylates the guanine in position
C7M18_RS07865	COG1358	cellular component organization or biogenesis
C7M18_RS07890	COG0596	Alpha beta hydrolase
C7M18_RS07895	COG0051	transcription antitermination factor activity, RNA binding
C7M18_RS07910	COG0089	rRNA binding
C7M18_RS07920	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M18_RS07925	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M18_RS07935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M18_RS07940	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M18_RS07990	COG1841	ribosomal large subunit assembly
C7M18_RS08000	COG0201	protein transport
C7M18_RS08010	COG0024	Methionine aminopeptidase
C7M18_RS08020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M18_RS08025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M18_RS08050	COG1122	ATPase activity
C7M18_RS08055	COG1122	ATPase activity
C7M18_RS08060	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M18_RS08080	COG2226	methyltransferase
C7M18_RS08085	COG2318	DinB family
C7M18_RS08095	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS08100	COG0489	protein tyrosine kinase activity
C7M18_RS08110	COG2194	sulfuric ester hydrolase activity
C7M18_RS08115	COG0726	polysaccharide deacetylase
C7M18_RS08150	COG2856	Zn peptidase
C7M18_RS08170	COG2369	cell adhesion
C7M18_RS08180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M18_RS08185	COG4653	Phage capsid family
C7M18_RS08200	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS08200	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS08200	COG1388	LysM domain
C7M18_RS08215	COG5444	nuclease activity
C7M18_RS08220	COG0457	Tetratricopeptide repeat
C7M18_RS08225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M18_RS08260	COG0738	Major facilitator superfamily
C7M18_RS08265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS08280	COG0659	secondary active sulfate transmembrane transporter activity
C7M18_RS08285	COG0385	Bile acid
C7M18_RS08290	COG2819	hydrolase of the alpha beta superfamily
C7M18_RS08295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS08300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS08305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M18_RS08310	COG2207	Transcriptional regulator
C7M18_RS08310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M18_RS08315	COG3876	Protein conserved in bacteria
C7M18_RS08320	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M18_RS08325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M18_RS08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS08330	COG1263	PTS System
C7M18_RS08340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS08345	COG1683	Conserved Protein
C7M18_RS08375	COG1595	DNA-templated transcription, initiation
C7M18_RS08380	COG5662	AntiSigma factor
C7M18_RS08385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M18_RS08390	COG4856	YbbR-like protein
C7M18_RS08440	COG1346	cytolysis
C7M18_RS08445	COG1380	Effector of murein hydrolase LrgA
C7M18_RS08450	COG1846	Transcriptional regulator
C7M18_RS08455	COG1113	amino acid transport
C7M18_RS08460	COG1011	Hydrolase
C7M18_RS08465	COG4585	Histidine kinase
C7M18_RS08470	COG2197	response regulator
C7M18_RS08475	COG1131	(ABC) transporter
C7M18_RS08515	COG0531	amino acid
C7M18_RS08540	COG0584	glycerophosphoryl diester phosphodiesterase
C7M18_RS08545	COG2271	Major facilitator Superfamily
C7M18_RS08555	COG2368	4-hydroxyphenylacetate
C7M18_RS08565	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS08580	COG0371	Dehydrogenase
C7M18_RS08590	COG1183	phosphatidylcholine synthase activity
C7M18_RS08595	COG0586	Pfam SNARE associated Golgi protein
C7M18_RS08600	COG0688	phosphatidylethanolamine metabolic process
C7M18_RS08615	COG1301	dicarboxylic acid transport
C7M18_RS08620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS08625	COG0833	amino acid
C7M18_RS08630	COG2040	homocysteine
C7M18_RS08635	COG1115	amino acid carrier protein
C7M18_RS08640	COG2066	Belongs to the glutaminase family
C7M18_RS08645	COG4191	Histidine kinase
C7M18_RS08650	COG0784	Response regulator, receiver
C7M18_RS08655	COG3173	Aminoglycoside phosphotransferase
C7M18_RS08670	COG3773	Cell wall hydrolase
C7M18_RS08675	COG3540	Alkaline phosphatase
C7M18_RS08680	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M18_RS08685	COG0805	protein transport
C7M18_RS08695	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M18_RS08700	COG0477	Major facilitator Superfamily
C7M18_RS08705	COG1309	transcriptional regulator
C7M18_RS08710	COG0252	asparaginase activity
C7M18_RS08715	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M18_RS08720	COG3012	SEC-C Motif Domain Protein
C7M18_RS08720	COG1405	negative regulation of cell septum assembly
C7M18_RS08725	COG0667	Aldo Keto reductase
C7M18_RS08735	COG1595	DNA-templated transcription, initiation
C7M18_RS08740	COG1595	DNA-templated transcription, initiation
C7M18_RS08745	COG1876	peptidase activity
C7M18_RS08750	COG0457	Tetratricopeptide repeat
C7M18_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS08760	COG0366	Alpha amylase catalytic
C7M18_RS08765	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M18_RS08770	COG1121	(ABC) transporter
C7M18_RS08775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M18_RS08780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M18_RS08785	COG2310	stress, protein
C7M18_RS08790	COG2310	stress, protein
C7M18_RS08795	COG2310	stress, protein
C7M18_RS08800	COG0861	Integral membrane protein TerC family
C7M18_RS08810	COG3853	Toxic anion resistance protein (TelA)
C7M18_RS08815	COG0477	Major facilitator Superfamily
C7M18_RS08820	COG4175	Glycine betaine
C7M18_RS08820	COG0517	IMP dehydrogenase activity
C7M18_RS08825	COG4176	ABC-type proline glycine betaine transport system permease component
C7M18_RS08830	COG2113	Glycine betaine
C7M18_RS08835	COG1473	amidohydrolase
C7M18_RS08840	COG1288	antiporter activity
C7M18_RS08850	COG0366	Alpha amylase catalytic
C7M18_RS08860	COG2814	Major facilitator Superfamily
C7M18_RS08865	COG1846	Transcriptional regulator
C7M18_RS08870	COG1280	lysine exporter protein (LysE YggA)
C7M18_RS08875	COG3403	YqcI/YcgG family
C7M18_RS08880	COG1113	amino acid transport
C7M18_RS08885	COG3665	Urea carboxylase-associated protein
C7M18_RS08900	COG1660	Displays ATPase and GTPase activities
C7M18_RS08905	COG1082	Xylose isomerase domain protein TIM barrel
C7M18_RS08910	COG2271	Major facilitator Superfamily
C7M18_RS08915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M18_RS08920	COG3458	cephalosporin-C deacetylase activity
C7M18_RS08925	COG3541	Predicted nucleotidyltransferase
C7M18_RS08930	COG0506	proline dehydrogenase activity
C7M18_RS08935	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS08940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M18_RS08945	COG2508	Transcriptional regulator
C7M18_RS08955	COG1587	Uroporphyrinogen-III synthase
C7M18_RS08955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M18_RS08960	COG2146	nitrite reductase [NAD(P)H] activity
C7M18_RS08965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M18_RS08970	COG0243	molybdopterin cofactor binding
C7M18_RS08975	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M18_RS08980	COG2223	nitrite transmembrane transporter activity
C7M18_RS08985	COG0523	cobalamin synthesis protein
C7M18_RS08990	COG1063	alcohol dehydrogenase
C7M18_RS08995	COG1714	RDD family
C7M18_RS09005	COG2723	6-phospho-beta-galactosidase activity
C7M18_RS09015	COG3209	COG3209 Rhs family protein
C7M18_RS09020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M18_RS09025	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C7M18_RS09030	COG1733	regulation of RNA biosynthetic process
C7M18_RS09035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS09040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS09045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS09050	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M18_RS09065	COG2364	Membrane
C7M18_RS09070	COG1126	abc transporter atp-binding protein
C7M18_RS09075	COG0765	amino acid transport
C7M18_RS09080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS09085	COG0583	DNA-binding transcription factor activity
C7M18_RS09090	COG0163	prenyltransferase activity
C7M18_RS09095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M18_RS09115	COG3104	oligopeptide transport
C7M18_RS09120	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M18_RS09130	COG0697	spore germination
C7M18_RS09140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M18_RS09155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS09160	COG0765	amino acid transport
C7M18_RS09165	COG1126	abc transporter atp-binding protein
C7M18_RS09175	COG2079	MmgE PrpD family protein
C7M18_RS09180	COG1136	(ABC) transporter
C7M18_RS09185	COG0577	efflux transmembrane transporter activity
C7M18_RS09190	COG0745	RESPONSE REGULATOR receiver
C7M18_RS09195	COG3850	Histidine kinase
C7M18_RS09195	COG5002	protein histidine kinase activity
C7M18_RS09200	COG0457	Tetratricopeptide repeat
C7M18_RS09215	COG0527	aspartate kinase activity
C7M18_RS09220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M18_RS09225	COG4605	iron ion homeostasis
C7M18_RS09230	COG4604	ABC transporter, ATP-binding protein
C7M18_RS09235	COG4607	ABC-type enterochelin transport system periplasmic component
C7M18_RS09240	COG2814	Major facilitator Superfamily
C7M18_RS09245	COG1309	transcriptional regulator
C7M18_RS09250	COG0778	Nitroreductase
C7M18_RS09255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M18_RS09260	COG0640	Transcriptional regulator
C7M18_RS09265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS09270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS09275	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS09280	COG4975	Glucose uptake
C7M18_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS09290	COG4549	nuclear export factor GLE1
C7M18_RS09295	COG1276	copper resistance
C7M18_RS09295	COG2372	response to copper ion
C7M18_RS09300	COG1349	DNA-binding transcription factor activity
C7M18_RS09310	COG2213	PTS system mannitol-specific
C7M18_RS09315	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS09325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M18_RS09335	COG0561	phosphatase activity
C7M18_RS09345	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M18_RS09355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M18_RS09360	COG1984	allophanate hydrolase subunit 2
C7M18_RS09365	COG1414	Transcriptional regulator
C7M18_RS09370	COG2755	lipolytic protein G-D-S-L family
C7M18_RS09380	COG2329	Antibiotic biosynthesis monooxygenase
C7M18_RS09385	COG0768	penicillin binding
C7M18_RS09390	COG4989	oxidoreductase activity
C7M18_RS09395	COG3711	transcriptional antiterminator
C7M18_RS09400	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS09405	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS09410	COG1917	Cupin 2, conserved barrel domain protein
C7M18_RS09415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS09420	COG3871	stress protein (general stress protein 26)
C7M18_RS09430	COG2814	Major facilitator Superfamily
C7M18_RS09435	COG1522	sequence-specific DNA binding
C7M18_RS09440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M18_RS09440	COG0551	DNA topoisomerase type I activity
C7M18_RS09445	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M18_RS09450	COG3706	GGDEF domain
C7M18_RS09455	COG5298	Protein conserved in bacteria
C7M18_RS09460	COG1215	transferase activity, transferring glycosyl groups
C7M18_RS09470	COG0531	amino acid
C7M18_RS09475	COG0494	nUDIX hydrolase
C7M18_RS09480	COG0028	Belongs to the TPP enzyme family
C7M18_RS09490	COG1388	LysM domain
C7M18_RS09490	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS09490	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS09530	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M18_RS09540	COG4876	unkown
C7M18_RS09550	COG2076	Multidrug Resistance protein
C7M18_RS09555	COG2217	Heavy metal translocating P-type atpase
C7M18_RS09560	COG3729	General stress protein
C7M18_RS09565	COG0662	Cupin 2, conserved barrel domain protein
C7M18_RS09570	COG2329	Antibiotic biosynthesis monooxygenase
C7M18_RS09575	COG3546	catalase activity
C7M18_RS09580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7M18_RS09585	COG3290	protein histidine kinase activity
C7M18_RS09590	COG4565	transcriptional regulatory protein
C7M18_RS09595	COG1301	dicarboxylic acid transport
C7M18_RS09600	COG0628	permease
C7M18_RS09605	COG1131	(ABC) transporter
C7M18_RS09610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M18_RS09620	COG1960	acyl-CoA dehydrogenase activity
C7M18_RS09635	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M18_RS09640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS09650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M18_RS09655	COG0513	Belongs to the DEAD box helicase family
C7M18_RS09660	COG3402	PFAM membrane-flanked domain
C7M18_RS09665	COG3428	Bacterial PH domain
C7M18_RS09670	COG0705	Rhomboid family
C7M18_RS09680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M18_RS09685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M18_RS09690	COG0864	Transcriptional regulator
C7M18_RS09695	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M18_RS09700	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS09705	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS09710	COG2172	sigma factor antagonist activity
C7M18_RS09715	COG2208	phosphoserine phosphatase activity
C7M18_RS09720	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS09730	COG1191	sigma factor activity
C7M18_RS09735	COG2208	phosphoserine phosphatase activity
C7M18_RS09740	COG2183	response to ionizing radiation
C7M18_RS09795	COG5444	nuclease activity
C7M18_RS09800	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M18_RS09805	COG0457	Tetratricopeptide repeat
C7M18_RS09810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M18_RS09815	COG0477	Major facilitator Superfamily
C7M18_RS09835	COG2030	dehydratase
C7M18_RS09850	COG1959	2 iron, 2 sulfur cluster binding
C7M18_RS09855	COG2910	NAD(P)H-binding
C7M18_RS09865	COG1278	Cold shock
C7M18_RS09870	COG1329	Transcriptional regulator
C7M18_RS09875	COG1794	racemase activity, acting on amino acids and derivatives
C7M18_RS09890	COG3621	Patatin-like phospholipase
C7M18_RS09900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M18_RS09910	COG0251	oxidation-reduction process
C7M18_RS09915	COG0814	amino acid
C7M18_RS09920	COG1473	amidohydrolase
C7M18_RS09925	COG1917	Cupin 2, conserved barrel domain protein
C7M18_RS09925	COG2207	Transcriptional regulator
C7M18_RS09935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS09940	COG0477	Major facilitator Superfamily
C7M18_RS10000	COG0351	phosphomethylpyrimidine kinase
C7M18_RS10015	COG1064	alcohol dehydrogenase
C7M18_RS10020	COG0789	Transcriptional regulator
C7M18_RS10030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS10045	COG2814	Major facilitator Superfamily
C7M18_RS10050	COG1309	transcriptional regulator
C7M18_RS10055	COG0697	spore germination
C7M18_RS10060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS10065	COG5577	PFAM Coat F domain
C7M18_RS10075	COG1063	alcohol dehydrogenase
C7M18_RS10080	COG5577	PFAM Coat F domain
C7M18_RS10095	COG4585	Histidine kinase
C7M18_RS10100	COG2197	response regulator
C7M18_RS10105	COG2409	Drug exporters of the RND superfamily
C7M18_RS10110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7M18_RS10120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS10125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS10135	COG2814	Major facilitator Superfamily
C7M18_RS10140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M18_RS10150	COG0730	response to heat
C7M18_RS10155	COG0456	acetyltransferase
C7M18_RS10160	COG4978	Transcriptional regulator
C7M18_RS10160	COG0789	Transcriptional regulator
C7M18_RS10165	COG0697	spore germination
C7M18_RS10170	COG1051	belongs to the nudix hydrolase family
C7M18_RS10175	COG2226	methyltransferase
C7M18_RS10180	COG0473	3-isopropylmalate dehydrogenase activity
C7M18_RS10185	COG1802	Transcriptional regulator
C7M18_RS10190	COG1819	glycosyl
C7M18_RS10205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M18_RS10210	COG1388	LysM domain
C7M18_RS10215	COG2814	Major facilitator Superfamily
C7M18_RS10220	COG2188	Transcriptional regulator
C7M18_RS10225	COG2186	Transcriptional regulator
C7M18_RS10230	COG2807	transmembrane transport
C7M18_RS10235	COG2076	Multidrug Resistance protein
C7M18_RS10240	COG2076	Multidrug Resistance protein
C7M18_RS10245	COG1309	transcriptional regulator
C7M18_RS10250	COG0531	amino acid
C7M18_RS10260	COG3832	glyoxalase III activity
C7M18_RS10265	COG0604	alcohol dehydrogenase
C7M18_RS10270	COG2814	Major facilitator Superfamily
C7M18_RS10310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M18_RS10315	COG0802	atpase or kinase
C7M18_RS10320	COG1214	PFAM Peptidase M22, glycoprotease
C7M18_RS10325	COG0456	acetyltransferase
C7M18_RS10330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M18_RS10335	COG0488	(ABC) transporter
C7M18_RS10350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M18_RS10355	COG0805	protein transport
C7M18_RS10365	COG1266	CAAX protease self-immunity
C7M18_RS10370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M18_RS10385	COG0457	Tetratricopeptide repeat
C7M18_RS10390	COG1063	alcohol dehydrogenase
C7M18_RS10395	COG2211	Major facilitator Superfamily
C7M18_RS10400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M18_RS10410	COG1842	Phage shock protein A
C7M18_RS10415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M18_RS10420	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M18_RS10425	COG4260	virion core protein, lumpy skin disease virus
C7M18_RS10430	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M18_RS10430	COG2755	lipolytic protein G-D-S-L family
C7M18_RS10440	COG1595	DNA-templated transcription, initiation
C7M18_RS10445	COG1063	alcohol dehydrogenase
C7M18_RS10450	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M18_RS10455	COG0823	Involved in the tonB-independent uptake of proteins
C7M18_RS10465	COG2132	Multicopper oxidase
C7M18_RS10470	COG1113	amino acid transport
C7M18_RS10475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M18_RS10480	COG0714	Associated with various cellular activities
C7M18_RS10485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M18_RS10490	COG1305	Transglutaminase-like
C7M18_RS10500	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M18_RS10520	COG2211	Major facilitator Superfamily
C7M18_RS10535	COG2252	PERMEase
C7M18_RS10540	COG3064	Membrane
C7M18_RS10560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M18_RS10565	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M18_RS10570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M18_RS10575	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M18_RS10580	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M18_RS10595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M18_RS10605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M18_RS10610	COG0138	bifunctional purine biosynthesis protein purh
C7M18_RS10615	COG0151	Belongs to the GarS family
C7M18_RS10625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M18_RS10630	COG1470	cell adhesion involved in biofilm formation
C7M18_RS10635	COG4496	protein, YerC YecD
C7M18_RS10640	COG0069	glutamate synthase activity
C7M18_RS10650	COG0210	DNA helicase
C7M18_RS10660	COG4851	CamS sex pheromone cAM373 precursor
C7M18_RS10665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M18_RS10670	COG1285	pathogenesis
C7M18_RS10675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M18_RS10695	COG1309	transcriptional regulator
C7M18_RS10700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M18_RS10705	COG1597	lipid kinase activity
C7M18_RS10710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M18_RS10720	COG1131	(ABC) transporter
C7M18_RS10765	COG5444	nuclease activity
C7M18_RS10790	COG3546	catalase activity
C7M18_RS10795	COG0454	-acetyltransferase
C7M18_RS10805	COG2323	membrane
C7M18_RS10810	COG2329	Antibiotic biosynthesis monooxygenase
C7M18_RS10815	COG0346	lactoylglutathione lyase activity
C7M18_RS10820	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS10825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7M18_RS10830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7M18_RS10835	COG4208	sulfate ABC transporter
C7M18_RS10845	COG5583	Uncharacterized small protein (DUF2292)
C7M18_RS10850	COG0196	riboflavin kinase activity
C7M18_RS10855	COG0670	Belongs to the BI1 family
C7M18_RS10860	COG1846	Transcriptional regulator
C7M18_RS10865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M18_RS10875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M18_RS10875	COG2124	cytochrome p450
C7M18_RS10890	COG1131	(ABC) transporter
C7M18_RS10900	COG1368	sulfuric ester hydrolase activity
C7M18_RS10905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7M18_RS10910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS10915	COG1442	glycosyl transferase family 8
C7M18_RS10920	COG1216	Glycosyl transferase, family 2
C7M18_RS10925	COG1442	glycosyl transferase family 8
C7M18_RS10930	COG2223	nitrite transmembrane transporter activity
C7M18_RS10935	COG0531	amino acid
C7M18_RS10940	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS10945	COG0840	transmembrane signaling receptor activity
C7M18_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS10955	COG0463	Glycosyl transferase, family 2
C7M18_RS10960	COG0488	(ABC) transporter
C7M18_RS10965	COG0789	Transcriptional regulator
C7M18_RS10970	COG2814	Major facilitator Superfamily
C7M18_RS10975	COG0488	(ABC) transporter
C7M18_RS10980	COG0513	Belongs to the DEAD box helicase family
C7M18_RS10990	COG2130	NADP-dependent
C7M18_RS11005	COG3866	Pectate lyase
C7M18_RS11010	COG0471	metal ion transport
C7M18_RS11030	COG0745	RESPONSE REGULATOR receiver
C7M18_RS11030	COG2972	Histidine kinase
C7M18_RS11035	COG3279	Response regulator of the LytR AlgR family
C7M18_RS11045	COG3764	Sortase (surface protein transpeptidase)
C7M18_RS11050	COG3290	protein histidine kinase activity
C7M18_RS11055	COG4565	transcriptional regulatory protein
C7M18_RS11060	COG3181	Tripartite tricarboxylate transporter family receptor
C7M18_RS11065	COG2851	Citrate transporter
C7M18_RS11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS11075	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M18_RS11085	COG2258	MOSC domain
C7M18_RS11105	COG0024	Methionine aminopeptidase
C7M18_RS11110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS11110	COG1263	PTS System
C7M18_RS11125	COG1368	sulfuric ester hydrolase activity
C7M18_RS11135	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M18_RS11150	COG1263	PTS System
C7M18_RS11150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS11155	COG0366	Alpha amylase catalytic
C7M18_RS11160	COG2188	Transcriptional regulator
C7M18_RS11165	COG0778	Nitroreductase
C7M18_RS11180	COG0737	Belongs to the 5'-nucleotidase family
C7M18_RS11185	COG0693	protein deglycase activity
C7M18_RS11190	COG1609	Transcriptional regulator
C7M18_RS11195	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M18_RS11205	COG2814	Major facilitator Superfamily
C7M18_RS11215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M18_RS11220	COG4980	gas vesicle protein
C7M18_RS11225	COG1295	ribonuclease BN
C7M18_RS11235	COG0477	Major facilitator Superfamily
C7M18_RS11240	COG0387	Pfam Sodium calcium exchanger
C7M18_RS11250	COG0668	transmembrane transport
C7M18_RS11255	COG0535	radical SAM domain protein
C7M18_RS11265	COG0726	polysaccharide deacetylase
C7M18_RS11280	COG0598	Magnesium transport protein CorA
C7M18_RS11285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M18_RS11290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M18_RS11300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M18_RS11305	COG4637	Psort location Cytoplasmic, score
C7M18_RS11310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M18_RS11315	COG0022	dehydrogenase e1 component
C7M18_RS11320	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M18_RS11325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M18_RS11330	COG3284	Transcriptional regulator
C7M18_RS11340	COG1486	melibiose metabolic process
C7M18_RS11345	COG1737	Transcriptional regulator
C7M18_RS11350	COG1263	PTS System
C7M18_RS11350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS11355	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M18_RS11360	COG1132	(ABC) transporter
C7M18_RS11365	COG1132	(ABC) transporter
C7M18_RS11370	COG2259	Doxx family
C7M18_RS11375	COG2514	catechol 2,3-dioxygenase activity
C7M18_RS11385	COG1695	Transcriptional regulator
C7M18_RS11390	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M18_RS11395	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M18_RS11400	COG3848	Pyruvate phosphate dikinase
C7M18_RS11400	COG0574	Belongs to the PEP-utilizing enzyme family
C7M18_RS11405	COG2732	(Barnase) inhibitor
C7M18_RS11410	COG2318	DinB family
C7M18_RS11415	COG2814	Major facilitator Superfamily
C7M18_RS11420	COG1846	Transcriptional regulator
C7M18_RS11425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M18_RS11425	COG0392	lysyltransferase activity
C7M18_RS11430	COG0384	phenazine biosynthesis protein PhzF
C7M18_RS11435	COG0778	Nitroreductase
C7M18_RS11450	COG1090	epimerase
C7M18_RS11465	COG2814	Major facilitator Superfamily
C7M18_RS11475	COG3591	Belongs to the peptidase S1B family
C7M18_RS11490	COG3103	Sh3 type 3 domain protein
C7M18_RS11495	COG5658	integral membrane protein
C7M18_RS11500	COG0596	Alpha beta hydrolase
C7M18_RS11505	COG0463	Glycosyl transferase, family 2
C7M18_RS11510	COG4485	Bacterial membrane protein, YfhO
C7M18_RS11515	COG1988	membrane-bound metal-dependent
C7M18_RS11520	COG1194	a g-specific adenine glycosylase
C7M18_RS11530	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS11550	COG1132	(ABC) transporter
C7M18_RS11555	COG4129	membrane
C7M18_RS11565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M18_RS11570	COG0735	belongs to the Fur family
C7M18_RS11680	COG1757	Na H antiporter
C7M18_RS11685	COG3340	Belongs to the peptidase S51 family
C7M18_RS11695	COG0277	FAD linked oxidase domain protein
C7M18_RS11705	COG0747	negative chemotaxis
C7M18_RS11710	COG0601	transmembrane transport
C7M18_RS11715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M18_RS11720	COG0444	Belongs to the ABC transporter superfamily
C7M18_RS11725	COG4608	Belongs to the ABC transporter superfamily
C7M18_RS11730	COG0753	catalase activity
C7M18_RS11740	COG1116	anion transmembrane transporter activity
C7M18_RS11745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M18_RS11750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M18_RS11770	COG1476	TRANSCRIPTIONal
C7M18_RS11780	COG3382	B3 4 domain protein
C7M18_RS11785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M18_RS11795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M18_RS11800	COG0789	Transcriptional regulator
C7M18_RS11805	COG1664	Polymer-forming cytoskeletal
C7M18_RS11810	COG1664	Polymer-forming cytoskeletal
C7M18_RS11815	COG2766	serine protein kinase
C7M18_RS11825	COG1846	Transcriptional regulator
C7M18_RS11830	COG1566	PFAM secretion protein HlyD family protein
C7M18_RS11835	COG2814	Major facilitator Superfamily
C7M18_RS11840	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M18_RS11855	COG1725	Transcriptional regulator
C7M18_RS11860	COG1131	(ABC) transporter
C7M18_RS11865	COG1131	(ABC) transporter
C7M18_RS11870	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M18_RS11875	COG1278	Cold shock
C7M18_RS11880	COG1464	Belongs to the NlpA lipoprotein family
C7M18_RS11885	COG3706	GGDEF domain
C7M18_RS11890	COG1823	symporter activity
C7M18_RS11910	COG5577	PFAM Coat F domain
C7M18_RS11915	COG4085	toxin activity
C7M18_RS11915	COG1525	nuclease
C7M18_RS11915	COG0737	Belongs to the 5'-nucleotidase family
C7M18_RS11920	COG3764	Sortase (surface protein transpeptidase)
C7M18_RS11925	COG0564	pseudouridine synthase activity
C7M18_RS11935	COG0517	IMP dehydrogenase activity
C7M18_RS11940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M18_RS11945	COG3153	acetyltransferase
C7M18_RS11945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M18_RS11950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M18_RS11955	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M18_RS11960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M18_RS11970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M18_RS11975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M18_RS11980	COG4585	Histidine kinase
C7M18_RS11980	COG2203	Gaf domain
C7M18_RS11985	COG2197	response regulator
C7M18_RS11990	COG0431	NADPH-dependent FMN reductase
C7M18_RS12005	COG1388	LysM domain
C7M18_RS12005	COG0791	NLP P60 protein
C7M18_RS12010	COG1959	2 iron, 2 sulfur cluster binding
C7M18_RS12015	COG0668	transmembrane transport
C7M18_RS12020	COG2719	SpoVR family
C7M18_RS12025	COG1785	Belongs to the alkaline phosphatase family
C7M18_RS12030	COG1388	LysM domain
C7M18_RS12030	COG0791	NLP P60 protein
C7M18_RS12035	COG0583	DNA-binding transcription factor activity
C7M18_RS12040	COG0372	Belongs to the citrate synthase family
C7M18_RS12045	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS12050	COG0531	amino acid
C7M18_RS12055	COG0733	neurotransmitter:sodium symporter activity
C7M18_RS12070	COG1595	DNA-templated transcription, initiation
C7M18_RS12075	COG0204	Acyl-transferase
C7M18_RS12080	COG1253	flavin adenine dinucleotide binding
C7M18_RS12085	COG0789	Transcriptional regulator
C7M18_RS12090	COG0436	Aminotransferase
C7M18_RS12095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M18_RS12100	COG1253	flavin adenine dinucleotide binding
C7M18_RS12105	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M18_RS12110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M18_RS12115	COG0584	glycerophosphoryl diester phosphodiesterase
C7M18_RS12125	COG0668	transmembrane transport
C7M18_RS12135	COG0726	polysaccharide deacetylase
C7M18_RS12140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M18_RS12145	COG3226	Transcriptional regulator
C7M18_RS12155	COG0589	response to stress
C7M18_RS12160	COG1132	(ABC) transporter
C7M18_RS12165	COG1132	(ABC) transporter
C7M18_RS12170	COG0702	epimerase
C7M18_RS12185	COG0189	ligase activity
C7M18_RS12190	COG0189	ligase activity
C7M18_RS12205	COG4335	DNA alkylation repair
C7M18_RS12210	COG0561	phosphatase activity
C7M18_RS12215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M18_RS12225	COG0475	glutathione-regulated potassium exporter activity
C7M18_RS12230	COG0490	domain, Protein
C7M18_RS12240	COG1024	Enoyl-CoA hydratase
C7M18_RS12250	COG4152	abc transporter atp-binding protein
C7M18_RS12255	COG1668	transmembrane transport
C7M18_RS12260	COG0420	3'-5' exonuclease activity
C7M18_RS12265	COG4717	serine-type aminopeptidase activity
C7M18_RS12280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M18_RS12315	COG4980	gas vesicle protein
C7M18_RS12330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M18_RS12335	COG0537	adenosine 5'-monophosphoramidase activity
C7M18_RS12340	COG1131	(ABC) transporter
C7M18_RS12345	COG4473	ABC transporter
C7M18_RS12355	COG1473	amidohydrolase
C7M18_RS12360	COG3069	C4-dicarboxylate transmembrane transporter activity
C7M18_RS12365	COG2329	Antibiotic biosynthesis monooxygenase
C7M18_RS12370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M18_RS12390	COG1309	transcriptional regulator
C7M18_RS12395	COG1511	domain protein
C7M18_RS12400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M18_RS12410	COG1363	Peptidase, m42
C7M18_RS12415	COG1301	dicarboxylic acid transport
C7M18_RS12425	COG1234	tRNA 3'-trailer cleavage
C7M18_RS12430	COG0095	Lipoate-protein ligase
C7M18_RS12435	COG0702	epimerase
C7M18_RS12440	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS12450	COG0501	Belongs to the peptidase M48B family
C7M18_RS12455	COG1404	Belongs to the peptidase S8 family
C7M18_RS12465	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M18_RS12470	COG0406	alpha-ribazole phosphatase activity
C7M18_RS12475	COG0183	Belongs to the thiolase family
C7M18_RS12480	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS12485	COG1268	BioY protein
C7M18_RS12490	COG0840	transmembrane signaling receptor activity
C7M18_RS12495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M18_RS12495	COG0723	plastoquinol--plastocyanin reductase activity
C7M18_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS12510	COG4903	ComK protein
C7M18_RS12515	COG5646	InterPro IPR014922
C7M18_RS12540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M18_RS12555	COG0398	Pfam SNARE associated Golgi protein
C7M18_RS12560	COG0681	Belongs to the peptidase S26 family
C7M18_RS12565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M18_RS12570	COG1846	Transcriptional regulator
C7M18_RS12575	COG3180	Ammonia monooxygenase
C7M18_RS12580	COG2814	Major facilitator Superfamily
C7M18_RS12590	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M18_RS12595	COG2323	membrane
C7M18_RS12610	COG0420	3'-5' exonuclease activity
C7M18_RS12615	COG0419	ATPase involved in DNA repair
C7M18_RS12620	COG1403	HNH endonuclease
C7M18_RS12660	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M18_RS12675	COG0367	asparagine synthase
C7M18_RS12680	COG1562	ergosterol biosynthetic process
C7M18_RS12685	COG0534	Mate efflux family protein
C7M18_RS12690	COG2207	Transcriptional regulator
C7M18_RS12690	COG1917	Cupin 2, conserved barrel domain protein
C7M18_RS12695	COG1609	Transcriptional regulator
C7M18_RS12700	COG0673	inositol 2-dehydrogenase activity
C7M18_RS12705	COG2318	DinB family
C7M18_RS12710	COG1357	PFAM Pentapeptide repeats (8 copies)
C7M18_RS12715	COG2153	protein acetylation
C7M18_RS12720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M18_RS12720	COG0646	methionine synthase
C7M18_RS12730	COG2996	Protein conserved in bacteria
C7M18_RS12740	COG0840	transmembrane signaling receptor activity
C7M18_RS12745	COG2124	cytochrome p450
C7M18_RS12755	COG1307	EDD domain protein, DegV family
C7M18_RS12760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS12775	COG0561	phosphatase activity
C7M18_RS12780	COG1073	alpha beta
C7M18_RS12785	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M18_RS12795	COG0277	FAD linked oxidase domain protein
C7M18_RS12800	COG2271	Major facilitator Superfamily
C7M18_RS12820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M18_RS12825	COG0505	Belongs to the CarA family
C7M18_RS12830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M18_RS12835	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M18_RS12850	COG2267	carboxylic ester hydrolase activity
C7M18_RS12860	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M18_RS12875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M18_RS12880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M18_RS12885	COG5504	Zn-dependent protease
C7M18_RS12890	COG0444	Belongs to the ABC transporter superfamily
C7M18_RS12895	COG4608	Belongs to the ABC transporter superfamily
C7M18_RS12905	COG0601	transmembrane transport
C7M18_RS12910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M18_RS12920	COG0180	Tryptophanyl-tRNA synthetase
C7M18_RS12925	COG4166	transmembrane transport
C7M18_RS12930	COG0601	transmembrane transport
C7M18_RS12935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M18_RS12940	COG0444	Belongs to the ABC transporter superfamily
C7M18_RS12945	COG4608	Belongs to the ABC transporter superfamily
C7M18_RS12955	COG0456	acetyltransferase
C7M18_RS12960	COG1393	Belongs to the ArsC family
C7M18_RS12965	COG0861	Integral membrane protein TerC family
C7M18_RS12970	COG4862	establishment of competence for transformation
C7M18_RS12975	COG4469	Competence protein
C7M18_RS12980	COG1164	Oligoendopeptidase f
C7M18_RS12990	COG2346	COG2346, Truncated hemoglobins
C7M18_RS12995	COG0741	lytic transglycosylase activity
C7M18_RS13000	COG4116	CYTH
C7M18_RS13010	COG2357	RelA SpoT domain protein
C7M18_RS13015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M18_RS13020	COG0564	pseudouridine synthase activity
C7M18_RS13030	COG0475	glutathione-regulated potassium exporter activity
C7M18_RS13030	COG0569	domain protein
C7M18_RS13035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M18_RS13040	COG0352	thiamine-phosphate diphosphorylase activity
C7M18_RS13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M18_RS13050	COG2104	thiamine diphosphate biosynthetic process
C7M18_RS13060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M18_RS13065	COG0351	phosphomethylpyrimidine kinase
C7M18_RS13070	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M18_RS13125	COG0210	DNA helicase
C7M18_RS13145	COG1131	(ABC) transporter
C7M18_RS13155	COG2153	protein acetylation
C7M18_RS13165	COG2382	esterase
C7M18_RS13170	COG0626	cystathionine gamma-synthase activity
C7M18_RS13175	COG0626	cystathionine gamma-synthase activity
C7M18_RS13205	COG5444	nuclease activity
C7M18_RS13230	COG3655	Transcriptional regulator
C7M18_RS13285	COG0135	phosphoribosylanthranilate isomerase activity
C7M18_RS13305	COG1595	DNA-templated transcription, initiation
C7M18_RS13330	COG2367	Beta-lactamase
C7M18_RS13335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M18_RS13340	COG0477	Major facilitator Superfamily
C7M18_RS13345	COG1846	Transcriptional regulator
C7M18_RS13355	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M18_RS13360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M18_RS13365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7M18_RS13370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS13370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M18_RS13375	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M18_RS13405	COG1285	pathogenesis
C7M18_RS13420	COG2205	protein histidine kinase activity
C7M18_RS13430	COG3383	formate dehydrogenase (NAD+) activity
C7M18_RS13435	COG2427	Protein of unknown function (DUF1641)
C7M18_RS13440	COG2124	cytochrome p450
C7M18_RS13445	COG1819	glycosyl
C7M18_RS13455	COG1587	Uroporphyrinogen-III synthase
C7M18_RS13460	COG0390	transport system, permease component
C7M18_RS13465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M18_RS13470	COG0697	spore germination
C7M18_RS13475	COG4297	protein containing double-stranded beta helix domain
C7M18_RS13485	COG1252	NADH dehydrogenase
C7M18_RS13495	COG2211	Major facilitator Superfamily
C7M18_RS13500	COG1609	Transcriptional regulator
C7M18_RS13505	COG0246	Mannitol dehydrogenase
C7M18_RS13510	COG2721	sulfolactate sulfo-lyase activity
C7M18_RS13515	COG0730	response to heat
C7M18_RS13520	COG2318	DinB family
C7M18_RS13525	COG0457	Tetratricopeptide repeat
C7M18_RS13535	COG1388	LysM domain
C7M18_RS13535	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS13535	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS13545	COG4195	phage-related replication protein
C7M18_RS13550	COG3546	catalase activity
C7M18_RS13555	COG2856	Zn peptidase
C7M18_RS13560	COG1396	sequence-specific DNA binding
C7M18_RS13570	COG1522	sequence-specific DNA binding
C7M18_RS13575	COG1484	DNA-dependent DNA replication
C7M18_RS13590	COG1595	DNA-templated transcription, initiation
C7M18_RS13595	COG3728	DNA packaging
C7M18_RS13595	COG5484	DNA packaging
C7M18_RS13600	COG1783	phage Terminase large subunit
C7M18_RS13605	COG5518	Phage portal protein
C7M18_RS13610	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M18_RS13615	COG4653	Phage capsid family
C7M18_RS13665	COG3953	SLT domain
C7M18_RS13665	COG5412	phage tail tape measure protein
C7M18_RS13665	COG3953	SLT domain
C7M18_RS13665	COG5412	phage tail tape measure protein
C7M18_RS13665	COG5412	phage tail tape measure protein
C7M18_RS13665	COG3953	SLT domain
C7M18_RS13670	COG1652	LysM domain
C7M18_RS13675	COG4193	domain, Protein
C7M18_RS13685	COG3628	GPW Gp25 family protein
C7M18_RS13690	COG3299	homolog of phage Mu protein gp47
C7M18_RS13695	COG3778	Protein conserved in bacteria
C7M18_RS13735	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS13735	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS13750	COG0306	phosphate transporter
C7M18_RS13755	COG1392	Phosphate transport regulator
C7M18_RS13760	COG0531	amino acid
C7M18_RS13765	COG0346	lactoylglutathione lyase activity
C7M18_RS13770	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M18_RS13775	COG0463	Glycosyl transferase, family 2
C7M18_RS13780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M18_RS13785	COG0477	Major facilitator Superfamily
C7M18_RS13790	COG2362	D-Aminopeptidase
C7M18_RS13795	COG0601	transmembrane transport
C7M18_RS13800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M18_RS13805	COG0444	Belongs to the ABC transporter superfamily
C7M18_RS13810	COG4166	transmembrane transport
C7M18_RS13815	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M18_RS13820	COG4948	Mandelate Racemase Muconate Lactonizing
C7M18_RS13825	COG0791	NLP P60 protein
C7M18_RS13830	COG4608	Belongs to the ABC transporter superfamily
C7M18_RS13835	COG2706	6-phosphogluconolactonase activity
C7M18_RS13840	COG1834	amidinotransferase
C7M18_RS13845	COG1607	acyl-coa hydrolase
C7M18_RS13850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS13855	COG2076	Multidrug Resistance protein
C7M18_RS13860	COG2076	Multidrug Resistance protein
C7M18_RS13865	COG0788	formyltetrahydrofolate deformylase activity
C7M18_RS13870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M18_RS13880	COG1764	response to oxidative stress
C7M18_RS13885	COG1846	Transcriptional regulator
C7M18_RS13890	COG1764	response to oxidative stress
C7M18_RS13905	COG0463	Glycosyl transferase, family 2
C7M18_RS13905	COG0457	Tetratricopeptide repeat
C7M18_RS13915	COG2814	Major facilitator Superfamily
C7M18_RS13920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M18_RS13930	COG1404	Belongs to the peptidase S8 family
C7M18_RS13935	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS13940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M18_RS13945	COG1122	ATPase activity
C7M18_RS13950	COG4721	ABC-type cobalt transport system, permease component
C7M18_RS13955	COG1388	LysM domain
C7M18_RS13955	COG3858	chitin binding
C7M18_RS13970	COG2239	Acts as a magnesium transporter
C7M18_RS13975	COG0789	Transcriptional regulator
C7M18_RS13990	COG1846	Transcriptional regulator
C7M18_RS13995	COG0726	polysaccharide deacetylase
C7M18_RS14000	COG1793	dna ligase
C7M18_RS14000	COG3285	dna ligase
C7M18_RS14005	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M18_RS14010	COG0586	Pfam SNARE associated Golgi protein
C7M18_RS14015	COG0861	Integral membrane protein TerC family
C7M18_RS14020	COG1191	sigma factor activity
C7M18_RS14045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M18_RS14050	COG2323	membrane
C7M18_RS14060	COG3594	Acyltransferase
C7M18_RS14065	COG5002	protein histidine kinase activity
C7M18_RS14070	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M18_RS14085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M18_RS14090	COG0436	Aminotransferase
C7M18_RS14120	COG3852	Histidine kinase
C7M18_RS14125	COG1846	Transcriptional regulator
C7M18_RS14130	COG1360	Flagellar Motor Protein
C7M18_RS14135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M18_RS14140	COG0542	response to heat
C7M18_RS14145	COG3949	Membrane
C7M18_RS14160	COG0720	synthase
C7M18_RS14165	COG0602	queuosine metabolic process
C7M18_RS14175	COG1733	regulation of RNA biosynthetic process
C7M18_RS14180	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS14230	COG4873	Protein conserved in bacteria
C7M18_RS14240	COG3773	Cell wall hydrolase
C7M18_RS14245	COG2244	polysaccharide biosynthetic process
C7M18_RS14250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS14255	COG2217	Heavy metal translocating P-type atpase
C7M18_RS14260	COG0006	proline dipeptidase activity
C7M18_RS14265	COG1609	Transcriptional regulator
C7M18_RS14270	COG3711	transcriptional antiterminator
C7M18_RS14275	COG2190	(PTS) system
C7M18_RS14275	COG1263	PTS System
C7M18_RS14275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M18_RS14280	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS14285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M18_RS14295	COG1533	DNA photolyase activity
C7M18_RS14300	COG0840	transmembrane signaling receptor activity
C7M18_RS14305	COG2084	Dehydrogenase
C7M18_RS14310	COG2340	Cysteine-rich secretory protein family
C7M18_RS14315	COG0768	penicillin binding
C7M18_RS14320	COG4191	Histidine kinase
C7M18_RS14325	COG0436	Aminotransferase
C7M18_RS14330	COG0835	chemotaxis
C7M18_RS14330	COG0784	Response regulator, receiver
C7M18_RS14340	COG2814	Major facilitator Superfamily
C7M18_RS14345	COG1376	ErfK ybiS ycfS ynhG family protein
C7M18_RS14350	COG1408	metallophosphoesterase
C7M18_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS14365	COG2200	EAL domain
C7M18_RS14370	COG4703	Protein of unknown function (DUF1797)
C7M18_RS14375	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M18_RS14385	COG0517	IMP dehydrogenase activity
C7M18_RS14390	COG0583	DNA-binding transcription factor activity
C7M18_RS14395	COG0716	FMN binding
C7M18_RS14405	COG0716	FMN binding
C7M18_RS14425	COG0668	transmembrane transport
C7M18_RS14430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS14450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M18_RS14455	COG0303	'Molybdopterin
C7M18_RS14460	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M18_RS14465	COG0314	molybdopterin synthase activity
C7M18_RS14470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M18_RS14480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M18_RS14485	COG1136	(ABC) transporter
C7M18_RS14490	COG0577	efflux transmembrane transporter activity
C7M18_RS14495	COG1349	DNA-binding transcription factor activity
C7M18_RS14500	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M18_RS14505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M18_RS14505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M18_RS14505	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M18_RS14510	COG0681	Belongs to the peptidase S26 family
C7M18_RS14520	COG0488	(ABC) transporter
C7M18_RS14525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M18_RS14530	COG2309	aminopeptidase activity
C7M18_RS14540	COG1077	Cell shape determining protein MreB Mrl
C7M18_RS14545	COG2002	toxin-antitoxin pair type II binding
C7M18_RS14550	COG3852	Histidine kinase
C7M18_RS14555	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C7M18_RS14555	COG2105	PFAM AIG2 family protein
C7M18_RS14560	COG0569	domain protein
C7M18_RS14570	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M18_RS14580	COG0561	phosphatase activity
C7M18_RS14585	COG0242	peptide deformylase activity
C7M18_RS14595	COG0497	DNA recombination
C7M18_RS14605	COG3321	synthase
C7M18_RS14605	COG4221	oxidoreductase activity
C7M18_RS14605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS14610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS14610	COG0300	oxidoreductase activity
C7M18_RS14610	COG4221	oxidoreductase activity
C7M18_RS14610	COG3321	synthase
C7M18_RS14615	COG4221	oxidoreductase activity
C7M18_RS14615	COG3321	synthase
C7M18_RS14615	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS14615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS14620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS14620	COG3321	synthase
C7M18_RS14620	COG0300	oxidoreductase activity
C7M18_RS14620	COG4221	oxidoreductase activity
C7M18_RS14625	COG4221	oxidoreductase activity
C7M18_RS14625	COG3321	synthase
C7M18_RS14625	COG0300	oxidoreductase activity
C7M18_RS14625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS14630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS14630	COG0300	oxidoreductase activity
C7M18_RS14630	COG3321	synthase
C7M18_RS14630	COG4221	oxidoreductase activity
C7M18_RS14635	COG4221	oxidoreductase activity
C7M18_RS14635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS14635	COG3321	synthase
C7M18_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS14640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M18_RS14645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M18_RS14650	COG0022	dehydrogenase e1 component
C7M18_RS14655	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M18_RS14660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M18_RS14665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS14680	COG1982	Orn Lys Arg decarboxylase major
C7M18_RS14700	COG0483	inositol monophosphate 1-phosphatase activity
C7M18_RS14710	COG3227	Zinc metalloprotease (Elastase)
C7M18_RS14725	COG1595	DNA-templated transcription, initiation
C7M18_RS14755	COG4896	Protein conserved in bacteria
C7M18_RS14765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M18_RS14770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M18_RS14775	COG2066	Belongs to the glutaminase family
C7M18_RS14785	COG0772	Belongs to the SEDS family
C7M18_RS14790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M18_RS14805	COG2010	Cytochrome c
C7M18_RS14805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M18_RS14810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M18_RS14815	COG1845	cytochrome c oxidase, subunit III
C7M18_RS14820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M18_RS14825	COG3336	cytochrome c oxidase
C7M18_RS14835	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M18_RS14840	COG2340	Cysteine-rich secretory protein family
C7M18_RS14855	COG3679	Belongs to the UPF0342 family
C7M18_RS14865	COG0742	ribosomal rna small subunit methyltransferase
C7M18_RS14875	COG3314	Sporulation integral membrane protein YlbJ
C7M18_RS14880	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M18_RS14885	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M18_RS14900	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M18_RS14905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M18_RS14920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M18_RS14940	COG4839	cell division protein FtsL
C7M18_RS14950	COG0768	penicillin binding
C7M18_RS14970	COG0772	Belongs to the SEDS family
C7M18_RS14985	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M18_RS14990	COG0849	cell division
C7M18_RS14995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M18_RS15000	COG1404	Belongs to the peptidase S8 family
C7M18_RS15000	COG4412	M6 family metalloprotease domain protein
C7M18_RS15010	COG1191	sigma factor activity
C7M18_RS15015	COG1191	sigma factor activity
C7M18_RS15020	COG1119	ATPase activity
C7M18_RS15025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M18_RS15030	COG1873	PFAM PRC-barrel domain
C7M18_RS15040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M18_RS15050	COG0762	integral membrane protein
C7M18_RS15055	COG2302	S4 RNA-binding domain
C7M18_RS15060	COG3599	regulation of cell shape
C7M18_RS15065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M18_RS15070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M18_RS15080	COG0564	pseudouridine synthase activity
C7M18_RS15090	COG2233	PERMEase
C7M18_RS15100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M18_RS15105	COG0505	Belongs to the CarA family
C7M18_RS15110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M18_RS15125	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M18_RS15130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M18_RS15140	COG0306	phosphate transporter
C7M18_RS15155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M18_RS15160	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M18_RS15165	COG1648	precorrin-2 dehydrogenase activity
C7M18_RS15180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M18_RS15185	COG1561	YicC-like family, N-terminal region
C7M18_RS15190	COG2052	Domain of unknown function (DUF370)
C7M18_RS15195	COG0194	GDP metabolic process
C7M18_RS15205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M18_RS15210	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M18_RS15215	COG0242	peptide deformylase activity
C7M18_RS15225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M18_RS15225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M18_RS15235	COG0631	protein serine/threonine phosphatase activity
C7M18_RS15240	COG0515	serine threonine protein kinase
C7M18_RS15240	COG2815	serine threonine protein kinase
C7M18_RS15250	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M18_RS15255	COG1564	THIamine pyrophosphokinase
C7M18_RS15270	COG1302	Protein conserved in bacteria
C7M18_RS15275	COG1461	Dihydroxyacetone kinase
C7M18_RS15280	COG1760	l-serine dehydratase
C7M18_RS15285	COG1760	l-serine dehydratase
C7M18_RS15290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M18_RS15305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M18_RS15310	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS15315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15325	COG1196	nuclear chromosome segregation
C7M18_RS15330	COG0552	protein localization to endoplasmic reticulum
C7M18_RS15345	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M18_RS15355	COG1837	Belongs to the UPF0109 family
C7M18_RS15380	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M18_RS15395	COG2257	FlhB HrpN YscU SpaS Family
C7M18_RS15405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M18_RS15410	COG0758	DNA mediated transformation
C7M18_RS15415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M18_RS15425	COG4974	Belongs to the 'phage' integrase family
C7M18_RS15445	COG1815	bacterial-type flagellum-dependent cell motility
C7M18_RS15450	COG1558	bacterial-type flagellum-dependent cell motility
C7M18_RS15455	COG1677	Flagellar hook-basal body complex protein FliE
C7M18_RS15460	COG1766	The M ring may be actively involved in energy transduction
C7M18_RS15465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M18_RS15470	COG1317	bacterial-type flagellum organization
C7M18_RS15475	COG1157	protein secretion by the type III secretion system
C7M18_RS15480	COG2882	bacterial-type flagellum organization
C7M18_RS15485	COG3334	PFAM MgtE intracellular
C7M18_RS15490	COG3144	bacterial-type flagellum assembly
C7M18_RS15495	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M18_RS15500	COG4786	Flagellar basal body rod
C7M18_RS15505	COG1582	Flagellar protein (FlbD)
C7M18_RS15510	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M18_RS15515	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M18_RS15520	COG1776	CheC inhibitor of MCP methylation
C7M18_RS15520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M18_RS15525	COG2201	protein-glutamate methylesterase activity
C7M18_RS15530	COG3190	flagellar
C7M18_RS15535	COG1338	Plays a role in the flagellum-specific transport system
C7M18_RS15540	COG1987	bacterial-type flagellum assembly
C7M18_RS15545	COG1684	flagellar biosynthetic protein fliR
C7M18_RS15550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M18_RS15555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M18_RS15560	COG1419	protein localization to endoplasmic reticulum
C7M18_RS15565	COG0455	bacterial-type flagellum organization
C7M18_RS15570	COG2201	protein-glutamate methylesterase activity
C7M18_RS15575	COG0643	Histidine kinase
C7M18_RS15575	COG2198	Histidine kinase
C7M18_RS15580	COG0835	chemotaxis
C7M18_RS15585	COG1776	CheC inhibitor of MCP methylation
C7M18_RS15595	COG1191	sigma factor activity
C7M18_RS15625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M18_RS15630	COG4589	Belongs to the CDS family
C7M18_RS15640	COG0750	zinc metalloprotease
C7M18_RS15650	COG2176	DNA-directed DNA polymerase activity
C7M18_RS15660	COG0195	Participates in both transcription termination and antitermination
C7M18_RS15665	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M18_RS15670	COG1358	cellular component organization or biogenesis
C7M18_RS15680	COG1550	Protein conserved in bacteria
C7M18_RS15695	COG0196	riboflavin kinase activity
C7M18_RS15710	COG0726	polysaccharide deacetylase
C7M18_RS15715	COG0612	Peptidase, M16
C7M18_RS15720	COG1873	PFAM PRC-barrel domain
C7M18_RS15725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M18_RS15730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M18_RS15735	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M18_RS15740	COG0527	aspartate kinase activity
C7M18_RS15750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M18_RS15755	COG0740	serine-type endopeptidase activity
C7M18_RS15765	COG4980	gas vesicle protein
C7M18_RS15765	COG1674	ftsk spoiiie
C7M18_RS15770	COG2188	Transcriptional regulator
C7M18_RS15775	COG2814	Major facilitator Superfamily
C7M18_RS15780	COG1846	Transcriptional regulator
C7M18_RS15785	COG1033	growth of symbiont in host cell
C7M18_RS15785	COG2409	Drug exporters of the RND superfamily
C7M18_RS15790	COG0612	Peptidase, M16
C7M18_RS15795	COG0612	Peptidase, M16
C7M18_RS15800	COG0300	oxidoreductase activity
C7M18_RS15815	COG1426	Protein conserved in bacteria
C7M18_RS15820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M18_RS15835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M18_RS15845	COG1692	metallophosphoesterase
C7M18_RS15850	COG2359	stage V sporulation protein S
C7M18_RS15870	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M18_RS15890	COG0582	viral genome integration into host DNA
C7M18_RS15950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15955	COG3425	synthase
C7M18_RS15960	COG1024	Enoyl-CoA hydratase
C7M18_RS15965	COG1024	Enoyl-CoA hydratase
C7M18_RS15970	COG3321	synthase
C7M18_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS15970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS15970	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS15970	COG0300	oxidoreductase activity
C7M18_RS15975	COG4221	oxidoreductase activity
C7M18_RS15975	COG3321	synthase
C7M18_RS15975	COG0300	oxidoreductase activity
C7M18_RS15975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS15980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS15980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS15980	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS15980	COG3321	synthase
C7M18_RS15980	COG3321	synthase
C7M18_RS15980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS15980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS15985	COG4221	oxidoreductase activity
C7M18_RS15985	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS15985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS15985	COG3321	synthase
C7M18_RS15990	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7M18_RS15990	COG3321	synthase
C7M18_RS15990	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M18_RS15990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS15995	COG2124	cytochrome p450
C7M18_RS16000	COG3209	COG3209 Rhs family protein
C7M18_RS16005	COG3619	membrane
C7M18_RS16015	COG1404	Belongs to the peptidase S8 family
C7M18_RS16025	COG4195	phage-related replication protein
C7M18_RS16030	COG1764	response to oxidative stress
C7M18_RS16040	COG2076	Multidrug Resistance protein
C7M18_RS16080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M18_RS16085	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M18_RS16090	COG4112	unkown
C7M18_RS16095	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS16105	COG0464	growth
C7M18_RS16110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M18_RS16115	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M18_RS16120	COG0789	Transcriptional regulator
C7M18_RS16125	COG0174	glutamine synthetase
C7M18_RS16130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M18_RS16135	COG0506	proline dehydrogenase activity
C7M18_RS16150	COG0741	lytic transglycosylase activity
C7M18_RS16150	COG1196	nuclear chromosome segregation
C7M18_RS16150	COG0739	heme binding
C7M18_RS16175	COG2211	Major facilitator Superfamily
C7M18_RS16180	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M18_RS16195	COG1070	Carbohydrate kinase
C7M18_RS16200	COG0574	Belongs to the PEP-utilizing enzyme family
C7M18_RS16200	COG3848	Pyruvate phosphate dikinase
C7M18_RS16220	COG2378	regulation of single-species biofilm formation
C7M18_RS16225	COG2318	DinB family
C7M18_RS16230	COG1064	alcohol dehydrogenase
C7M18_RS16250	COG0456	acetyltransferase
C7M18_RS16255	COG5444	nuclease activity
C7M18_RS16300	COG3397	chitin binding
C7M18_RS16310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M18_RS16320	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M18_RS16325	COG0756	dUTP diphosphatase activity
C7M18_RS16330	COG4195	phage-related replication protein
C7M18_RS16360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M18_RS16370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M18_RS16390	COG0785	Cytochrome C biogenesis protein
C7M18_RS16395	COG2201	protein-glutamate methylesterase activity
C7M18_RS16400	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M18_RS16410	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M18_RS16425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M18_RS16430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS16450	COG0824	Thioesterase
C7M18_RS16460	COG4841	protein insertion into membrane
C7M18_RS16470	COG1832	CoA-binding protein
C7M18_RS16475	COG0187	DNA topoisomerase II activity
C7M18_RS16480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M18_RS16490	COG1115	amino acid carrier protein
C7M18_RS16500	COG1063	alcohol dehydrogenase
C7M18_RS16505	COG0800	Aldolase
C7M18_RS16510	COG1312	Catalyzes the dehydration of D-mannonate
C7M18_RS16515	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS16520	COG1609	Transcriptional regulator
C7M18_RS16525	COG2271	Major facilitator Superfamily
C7M18_RS16580	COG2205	protein histidine kinase activity
C7M18_RS16585	COG0745	RESPONSE REGULATOR receiver
C7M18_RS16595	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M18_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS16625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M18_RS16630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M18_RS16635	COG2610	gluconate transmembrane transporter activity
C7M18_RS16640	COG2124	cytochrome p450
C7M18_RS16645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M18_RS16660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M18_RS16670	COG2246	polysaccharide biosynthetic process
C7M18_RS16675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M18_RS16680	COG0586	Pfam SNARE associated Golgi protein
C7M18_RS16685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M18_RS16690	COG1024	Enoyl-CoA hydratase
C7M18_RS16695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M18_RS16700	COG0511	ligase activity, forming carbon-carbon bonds
C7M18_RS16705	COG0439	Biotin carboxylase
C7M18_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS16715	COG1960	acyl-CoA dehydrogenase activity
C7M18_RS16720	COG1649	PFAM Uncharacterised BCR, COG1649
C7M18_RS16730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7M18_RS16730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS16735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS16740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS16745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS16750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS16755	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M18_RS16760	COG2017	converts alpha-aldose to the beta-anomer
C7M18_RS16765	COG0534	Mate efflux family protein
C7M18_RS16780	COG0582	viral genome integration into host DNA
C7M18_RS16785	COG0166	Belongs to the GPI family
C7M18_RS16790	COG0405	Gamma-glutamyltransferase
C7M18_RS16795	COG2814	Major facilitator Superfamily
C7M18_RS16800	COG0640	Transcriptional regulator
C7M18_RS16805	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M18_RS16815	COG0604	alcohol dehydrogenase
C7M18_RS16835	COG0583	DNA-binding transcription factor activity
C7M18_RS16855	COG0493	'glutamate synthase
C7M18_RS16860	COG0070	glutamate synthase
C7M18_RS16860	COG0069	glutamate synthase activity
C7M18_RS16860	COG0067	glutamate synthase
C7M18_RS16865	COG0583	DNA-binding transcription factor activity
C7M18_RS16870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M18_RS16885	COG0300	oxidoreductase activity
C7M18_RS16890	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M18_RS16900	COG2814	Major facilitator Superfamily
C7M18_RS16905	COG1070	Carbohydrate kinase
C7M18_RS16910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M18_RS16915	COG0243	molybdopterin cofactor binding
C7M18_RS16945	COG5444	nuclease activity
C7M18_RS16950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M18_RS16955	COG0662	Cupin 2, conserved barrel domain protein
C7M18_RS16955	COG2207	Transcriptional regulator
C7M18_RS16960	COG1309	transcriptional regulator
C7M18_RS16965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS16975	COG0640	Transcriptional regulator
C7M18_RS16980	COG0741	lytic transglycosylase activity
C7M18_RS16985	COG2322	membrane
C7M18_RS17000	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M18_RS17010	COG3584	3D domain protein
C7M18_RS17010	COG1388	LysM domain
C7M18_RS17015	COG0514	ATP-dependent DNA helicase (RecQ)
C7M18_RS17025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M18_RS17030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M18_RS17045	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M18_RS17075	COG1012	belongs to the aldehyde dehydrogenase family
C7M18_RS17080	COG1657	PFAM Prenyltransferase squalene oxidase
C7M18_RS17085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M18_RS17090	COG0733	neurotransmitter:sodium symporter activity
C7M18_RS17095	COG0385	Bile acid
C7M18_RS17100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS17105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M18_RS17115	COG4548	von Willebrand factor, type A
C7M18_RS17120	COG0714	Associated with various cellular activities
C7M18_RS17125	COG2032	superoxide dismutase activity
C7M18_RS17130	COG1388	LysM domain
C7M18_RS17130	COG0791	NLP P60 protein
C7M18_RS17135	COG1819	glycosyl
C7M18_RS17140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M18_RS17150	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS17155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M18_RS17160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M18_RS17170	COG2962	Rard protein
C7M18_RS17185	COG1942	4-Oxalocrotonate Tautomerase
C7M18_RS17195	COG1733	regulation of RNA biosynthetic process
C7M18_RS17200	COG0778	Nitroreductase
C7M18_RS17205	COG0400	carboxylic ester hydrolase activity
C7M18_RS17210	COG0346	lactoylglutathione lyase activity
C7M18_RS17220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M18_RS17230	COG2723	6-phospho-beta-galactosidase activity
C7M18_RS17235	COG2188	Transcriptional regulator
C7M18_RS17240	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS17240	COG0793	Belongs to the peptidase S41A family
C7M18_RS17245	COG2226	methyltransferase
C7M18_RS17255	COG1876	peptidase activity
C7M18_RS17275	COG0671	phosphoesterase, PA-phosphatase related
C7M18_RS17300	COG1509	lysine 2,3-aminomutase activity
C7M18_RS17305	COG0456	acetyltransferase
C7M18_RS17310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M18_RS17315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M18_RS17320	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M18_RS17325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M18_RS17330	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7M18_RS17340	COG0456	acetyltransferase
C7M18_RS17345	COG0463	Glycosyl transferase, family 2
C7M18_RS17360	COG4641	Protein conserved in bacteria
C7M18_RS17370	COG1086	Polysaccharide biosynthesis protein
C7M18_RS17390	COG1388	LysM domain
C7M18_RS17395	COG0457	Tetratricopeptide repeat
C7M18_RS17460	COG3655	Transcriptional regulator
C7M18_RS17495	COG5444	nuclease activity
C7M18_RS17500	COG4282	regulation of fungal-type cell wall biogenesis
C7M18_RS17505	COG1525	nuclease
C7M18_RS17520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M18_RS17540	COG1846	Transcriptional regulator
C7M18_RS17545	COG4698	Protein conserved in bacteria
C7M18_RS17550	COG2755	lipolytic protein G-D-S-L family
C7M18_RS17555	COG1999	signal sequence binding
C7M18_RS17565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M18_RS17570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M18_RS17575	COG1272	protein, Hemolysin III
C7M18_RS17585	COG0204	Acyl-transferase
C7M18_RS17590	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M18_RS17605	COG2521	methyltransferase
C7M18_RS17605	COG2136	Putative SAM-dependent methyltransferase
C7M18_RS17620	COG1413	lyase activity
C7M18_RS17625	COG1418	mRNA catabolic process
C7M18_RS17630	COG0386	Belongs to the glutathione peroxidase family
C7M18_RS17640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M18_RS17650	COG1278	Cold shock
C7M18_RS17670	COG0328	RNA-DNA hybrid ribonuclease activity
C7M18_RS17675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M18_RS17680	COG0328	RNA-DNA hybrid ribonuclease activity
C7M18_RS17690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M18_RS17705	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M18_RS17715	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M18_RS17720	COG3424	synthase
C7M18_RS17740	COG1335	isochorismatase
C7M18_RS17750	COG2233	PERMEase
C7M18_RS17760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M18_RS17765	COG1199	ATP-dependent helicase activity
C7M18_RS17780	COG0116	Belongs to the methyltransferase superfamily
C7M18_RS17810	COG3359	exonuclease
C7M18_RS17815	COG1205	dead DEAH box helicase
C7M18_RS17815	COG1111	helicase
C7M18_RS17820	COG2190	(PTS) system
C7M18_RS17825	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M18_RS17865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M18_RS17865	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M18_RS17875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M18_RS17880	COG3935	DnaD domain protein
C7M18_RS17890	COG0436	Aminotransferase
C7M18_RS17895	COG5353	protein conserved in bacteria
C7M18_RS17905	COG1199	ATP-dependent helicase activity
C7M18_RS17905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M18_RS17935	COG0438	transferase activity, transferring glycosyl groups
C7M18_RS17940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M18_RS17955	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M18_RS17960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS17965	COG2140	Oxalate decarboxylase
C7M18_RS17975	COG4347	Protein of unknown function (DUF1405)
C7M18_RS17980	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M18_RS17980	COG2010	Cytochrome c
C7M18_RS17985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M18_RS17990	COG0723	plastoquinol--plastocyanin reductase activity
C7M18_RS18005	COG0457	Tetratricopeptide repeat
C7M18_RS18015	COG0287	Prephenate dehydrogenase
C7M18_RS18050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M18_RS18055	COG4401	Chorismate mutase type I
C7M18_RS18070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M18_RS18075	COG0105	UTP biosynthetic process
C7M18_RS18080	COG0142	geranyltranstransferase activity
C7M18_RS18090	COG0142	geranyltranstransferase activity
C7M18_RS18105	COG0776	regulation of translation
C7M18_RS18110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M18_RS18150	COG0539	negative regulation of cytoplasmic translation
C7M18_RS18165	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M18_RS18170	COG2959	enzyme of heme biosynthesis
C7M18_RS18175	COG3773	Cell wall hydrolase
C7M18_RS18175	COG3409	Peptidoglycan-binding domain 1 protein
C7M18_RS18180	COG2339	peptidase activity
C7M18_RS18185	COG0492	ferredoxin-NADP+ reductase activity
C7M18_RS18190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M18_RS18195	COG4862	establishment of competence for transformation
C7M18_RS18200	COG1408	metallophosphoesterase
C7M18_RS18210	COG1388	LysM domain
C7M18_RS18215	COG1266	CAAX protease self-immunity
C7M18_RS18220	COG0514	ATP-dependent DNA helicase (RecQ)
C7M18_RS18225	COG4955	Helix-turn-helix domain
C7M18_RS18230	COG1141	Ferredoxin
C7M18_RS18235	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M18_RS18240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M18_RS18250	COG1595	DNA-templated transcription, initiation
C7M18_RS18255	COG5002	protein histidine kinase activity
C7M18_RS18260	COG0745	RESPONSE REGULATOR receiver
C7M18_RS18265	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M18_RS18270	COG1333	cytochrome c biogenesis protein
C7M18_RS18275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M18_RS18280	COG1187	pseudouridine synthase activity
C7M18_RS18285	COG0700	Nucleoside recognition
C7M18_RS18290	COG2715	membrane protein required for spore maturation
C7M18_RS18295	COG1686	Belongs to the peptidase S11 family
C7M18_RS18320	COG1547	Domain of unknown function (DUF309)
C7M18_RS18325	COG0456	acetyltransferase
C7M18_RS18340	COG0307	riboflavin synthase, alpha
C7M18_RS18345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M18_RS18345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M18_RS18355	COG0681	Belongs to the peptidase S26 family
C7M18_RS18365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M18_RS18370	COG4086	secreted protein
C7M18_RS18375	COG0019	diaminopimelate decarboxylase activity
C7M18_RS18380	COG0697	spore germination
C7M18_RS18395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M18_RS18415	COG1191	sigma factor activity
C7M18_RS18425	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS18430	COG1686	Belongs to the peptidase S11 family
C7M18_RS18435	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M18_RS18440	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M18_RS18445	COG4974	Belongs to the 'phage' integrase family
C7M18_RS18455	COG0735	belongs to the Fur family
C7M18_RS18460	COG1300	Membrane
C7M18_RS18475	COG0281	malic enzyme
C7M18_RS18480	COG1757	Na H antiporter
C7M18_RS18485	COG1027	Aspartate ammonia-lyase
C7M18_RS18490	COG0252	asparaginase activity
C7M18_RS18495	COG1396	sequence-specific DNA binding
C7M18_RS18500	COG1379	DNA repair
C7M18_RS18505	COG0494	nUDIX hydrolase
C7M18_RS18515	COG0667	Aldo Keto reductase
C7M18_RS18525	COG1073	alpha beta
C7M18_RS18535	COG4918	Iron-sulphur cluster biosynthesis
C7M18_RS18540	COG0456	acetyltransferase
C7M18_RS18540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M18_RS18545	COG2329	Antibiotic biosynthesis monooxygenase
C7M18_RS18550	COG0456	acetyltransferase
C7M18_RS18555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M18_RS18580	COG0346	lactoylglutathione lyase activity
C7M18_RS18590	COG3048	D-serine ammonia-lyase activity
C7M18_RS18595	COG0300	oxidoreductase activity
C7M18_RS18600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS18605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M18_RS18610	COG1024	Enoyl-CoA hydratase
C7M18_RS18615	COG3425	synthase
C7M18_RS18620	COG2124	cytochrome p450
C7M18_RS18625	COG3321	synthase
C7M18_RS18625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS18625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS18630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18630	COG3321	synthase
C7M18_RS18630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS18635	COG3321	synthase
C7M18_RS18635	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS18635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18635	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18635	COG0300	oxidoreductase activity
C7M18_RS18640	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18640	COG0300	oxidoreductase activity
C7M18_RS18640	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS18640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18640	COG3321	synthase
C7M18_RS18645	COG3321	synthase
C7M18_RS18645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS18645	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS18650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18650	COG3321	synthase
C7M18_RS18650	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS18650	COG0300	oxidoreductase activity
C7M18_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18655	COG3321	synthase
C7M18_RS18655	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M18_RS18655	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M18_RS18655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M18_RS18660	COG1028	Short-chain dehydrogenase reductase Sdr
C7M18_RS18665	COG0318	PFAM AMP-dependent synthetase and ligase
C7M18_RS18680	COG2070	2-Nitropropane dioxygenase
C7M18_RS18680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M18_RS18685	COG0250	Participates in transcription elongation, termination and antitermination
C7M18_RS18710	COG0596	Alpha beta hydrolase
C7M18_RS18725	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M18_RS18730	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M18_RS18745	COG0706	membrane insertase activity
C7M18_RS18750	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M18_RS18755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M18_RS18760	COG0346	lactoylglutathione lyase activity
C7M18_RS18770	COG1376	ErfK ybiS ycfS ynhG family protein
C7M18_RS18775	COG4129	membrane
C7M18_RS18780	COG1126	abc transporter atp-binding protein
C7M18_RS18785	COG0765	amino acid transport
C7M18_RS18790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M18_RS18800	COG1597	lipid kinase activity
C7M18_RS18805	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M18_RS18810	COG0022	dehydrogenase e1 component
C7M18_RS18815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M18_RS18820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M18_RS18825	COG3426	butyrate kinase activity
C7M18_RS18830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M18_RS18835	COG0280	phosphate acetyltransferase
C7M18_RS18840	COG3290	protein histidine kinase activity
C7M18_RS18840	COG3829	transcription factor binding
C7M18_RS18850	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M18_RS18855	COG2079	MmgE PrpD family protein
C7M18_RS18860	COG0372	Belongs to the citrate synthase family
C7M18_RS18865	COG1960	acyl-CoA dehydrogenase activity
C7M18_RS18870	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M18_RS18875	COG0183	Belongs to the thiolase family
C7M18_RS18880	COG0584	glycerophosphoryl diester phosphodiesterase
C7M18_RS18885	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS18905	COG1902	pentaerythritol trinitrate reductase activity
C7M18_RS18920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M18_RS18925	COG0745	RESPONSE REGULATOR receiver
C7M18_RS18930	COG0750	zinc metalloprotease
C7M18_RS18935	COG0497	DNA recombination
C7M18_RS18945	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M18_RS18955	COG0142	geranyltranstransferase activity
C7M18_RS18965	COG1570	exodeoxyribonuclease VII activity
C7M18_RS18980	COG1302	Protein conserved in bacteria
C7M18_RS18985	COG0439	Biotin carboxylase
C7M18_RS18990	COG0511	ligase activity, forming carbon-carbon bonds
C7M18_RS19030	COG3854	ATPases associated with a variety of cellular activities
C7M18_RS19045	COG0006	proline dipeptidase activity
C7M18_RS19055	COG3872	metal-dependent enzyme
C7M18_RS19065	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M18_RS19080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M18_RS19100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M18_RS19115	COG1396	sequence-specific DNA binding
C7M18_RS19125	COG0681	Belongs to the peptidase S26 family
C7M18_RS19150	COG4940	Competence protein ComGF
C7M18_RS19160	COG4970	Tfp pilus assembly protein FimT
C7M18_RS19165	COG4537	Required for transformation and DNA binding
C7M18_RS19170	COG1459	type II secretion system
C7M18_RS19175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M18_RS19180	COG0598	Magnesium transport protein CorA
C7M18_RS19185	COG1253	flavin adenine dinucleotide binding
C7M18_RS19190	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M18_RS19200	COG1393	Belongs to the ArsC family
C7M18_RS19210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M18_RS19220	COG0011	TIGRFAM Protein of
C7M18_RS19230	COG2866	Carboxypeptidase
C7M18_RS19235	COG1940	carbohydrate kinase activity
C7M18_RS19240	COG4483	Protein conserved in bacteria
C7M18_RS19245	COG1757	Na H antiporter
C7M18_RS19255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M18_RS19260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M18_RS19270	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M18_RS19275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M18_RS19280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M18_RS19285	COG0581	inorganic phosphate transmembrane transporter activity
C7M18_RS19290	COG0573	inorganic phosphate transmembrane transporter activity
C7M18_RS19295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M18_RS19305	COG0477	Major facilitator Superfamily
C7M18_RS19310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M18_RS19315	COG2839	Protein conserved in bacteria
C7M18_RS19320	COG5521	maltodextrose utilization protein MalA
C7M18_RS19325	COG1388	LysM domain
C7M18_RS19335	COG4709	membrane
C7M18_RS19340	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M18_RS19345	COG0735	belongs to the Fur family
C7M18_RS19350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M18_RS19365	COG0513	Belongs to the DEAD box helicase family
C7M18_RS19380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M18_RS19385	COG2384	SAM-dependent methyltransferase
C7M18_RS19390	COG2010	Cytochrome c
C7M18_RS19395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M18_RS19400	COG0358	DNA primase activity
C7M18_RS19415	COG0517	IMP dehydrogenase activity
C7M18_RS19420	COG0751	glycine-tRNA ligase activity
C7M18_RS19440	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M18_RS19445	COG0295	cytidine deaminase activity
C7M18_RS19450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M18_RS19460	COG1480	7TM receptor with intracellular HD hydrolase
C7M18_RS19465	COG1702	phosphate starvation-inducible protein PhoH
C7M18_RS19470	COG0561	phosphatase activity
C7M18_RS19485	COG4864	UPF0365 protein
C7M18_RS19490	COG1030	water channel activity
C7M18_RS19495	COG1610	YqeY-like protein
C7M18_RS19500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M18_RS19505	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M18_RS19510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M18_RS19515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M18_RS19545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M18_RS19560	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M18_RS19575	COG1466	dna polymerase III delta subunit
C7M18_RS19590	COG0658	competence protein
C7M18_RS19590	COG2333	competence protein COMEC
C7M18_RS19595	COG2131	deaminase
C7M18_RS19600	COG1596	polysaccharide export
C7M18_RS19600	COG1555	photosystem II stabilization
C7M18_RS19605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M18_RS19610	COG2226	methyltransferase
C7M18_RS19615	COG0799	negative regulation of ribosome biogenesis
C7M18_RS19620	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M18_RS19630	COG1534	Rna-binding protein
C7M18_RS19635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M18_RS19640	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M18_RS19645	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M18_RS19655	COG2755	lipolytic protein G-D-S-L family
C7M18_RS19660	COG0726	polysaccharide deacetylase
C7M18_RS19665	COG0398	Pfam SNARE associated Golgi protein
C7M18_RS19690	COG3708	Transcriptional regulator
C7M18_RS19690	COG2207	Transcriptional regulator
C7M18_RS19695	COG0583	DNA-binding transcription factor activity
C7M18_RS19710	COG5002	protein histidine kinase activity
C7M18_RS19710	COG0642	Histidine kinase
C7M18_RS19715	COG0745	RESPONSE REGULATOR receiver
C7M18_RS19720	COG2311	Membrane
C7M18_RS19730	COG0454	-acetyltransferase