locus-tag	class	description
ETK69_RS00010	COG0592	DNA-directed DNA polymerase activity
ETK69_RS00015	COG2501	S4 domain
ETK69_RS00030	COG0187	DNA topoisomerase II activity
ETK69_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETK69_RS00070	COG0516	GMP reductase activity
ETK69_RS00070	COG0517	IMP dehydrogenase activity
ETK69_RS00075	COG1686	Belongs to the peptidase S11 family
ETK69_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
ETK69_RS00105	COG1428	Deoxynucleoside kinase
ETK69_RS00110	COG1428	Deoxynucleoside kinase
ETK69_RS00115	COG3858	chitin binding
ETK69_RS00115	COG1388	LysM domain
ETK69_RS00120	COG1335	isochorismatase
ETK69_RS00125	COG0590	tRNA wobble adenosine to inosine editing
ETK69_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETK69_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETK69_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ETK69_RS00195	COG3853	Toxic anion resistance protein (TelA)
ETK69_RS00200	COG1982	Orn Lys Arg decarboxylase major
ETK69_RS00210	COG3870	Protein conserved in bacteria
ETK69_RS00215	COG1728	Protein conserved in bacteria
ETK69_RS00220	COG0470	DNA polymerase III
ETK69_RS00225	COG1774	PSP1 C-terminal conserved region
ETK69_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETK69_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ETK69_RS00250	COG2002	toxin-antitoxin pair type II binding
ETK69_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETK69_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETK69_RS00260	COG0084	hydrolase, TatD family'
ETK69_RS00265	COG3583	domain protein
ETK69_RS00265	COG3584	3D domain protein
ETK69_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETK69_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETK69_RS00285	COG4466	Protein conserved in bacteria
ETK69_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETK69_RS00305	COG0251	oxidation-reduction process
ETK69_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETK69_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETK69_RS00345	COG2002	toxin-antitoxin pair type II binding
ETK69_RS00350	COG2244	polysaccharide biosynthetic process
ETK69_RS00355	COG3956	TIGRFAM MazG family protein
ETK69_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETK69_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ETK69_RS00380	COG1098	S1 RNA binding domain
ETK69_RS00395	COG2208	phosphoserine phosphatase activity
ETK69_RS00400	COG2304	oxidoreductase activity
ETK69_RS00405	COG0515	serine threonine protein kinase
ETK69_RS00410	COG0037	tRNA processing
ETK69_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETK69_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETK69_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETK69_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETK69_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETK69_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
ETK69_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETK69_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ETK69_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETK69_RS00475	COG1396	sequence-specific DNA binding
ETK69_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETK69_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETK69_RS00565	COG4463	regulation of RNA biosynthetic process
ETK69_RS00570	COG3880	PFAM UvrB UvrC protein
ETK69_RS00580	COG0542	response to heat
ETK69_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETK69_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ETK69_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
ETK69_RS00615	COG1045	serine acetyltransferase
ETK69_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETK69_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETK69_RS00635	COG3688	RNA-binding protein containing a PIN domain
ETK69_RS00640	COG1595	DNA-templated transcription, initiation
ETK69_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETK69_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
ETK69_RS00680	COG2813	Specifically methylates the guanine in position
ETK69_RS00695	COG1358	cellular component organization or biogenesis
ETK69_RS00720	COG0596	Alpha beta hydrolase
ETK69_RS00830	COG0201	protein transport
ETK69_RS00840	COG0024	Methionine aminopeptidase
ETK69_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ETK69_RS00880	COG1122	ATPase activity
ETK69_RS00885	COG1122	ATPase activity
ETK69_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETK69_RS00910	COG2226	methyltransferase
ETK69_RS00915	COG2318	DinB family
ETK69_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS00930	COG0489	protein tyrosine kinase activity
ETK69_RS00940	COG2194	sulfuric ester hydrolase activity
ETK69_RS00945	COG0726	polysaccharide deacetylase
ETK69_RS00980	COG2856	Zn peptidase
ETK69_RS00990	COG1395	domain, Protein
ETK69_RS01055	COG0305	Participates in initiation and elongation during chromosome replication
ETK69_RS01065	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ETK69_RS01160	COG1783	phage Terminase large subunit
ETK69_RS01165	COG5518	Phage portal protein
ETK69_RS01170	COG2369	cell adhesion
ETK69_RS01180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETK69_RS01185	COG4653	Phage capsid family
ETK69_RS01245	COG5280	Phage tail tape measure protein TP901
ETK69_RS01245	COG3953	SLT domain
ETK69_RS01250	COG1652	LysM domain
ETK69_RS01255	COG4193	domain, Protein
ETK69_RS01265	COG3628	GPW Gp25 family protein
ETK69_RS01270	COG3299	homolog of phage Mu protein gp47
ETK69_RS01275	COG3778	Protein conserved in bacteria
ETK69_RS01315	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS01315	COG1388	LysM domain
ETK69_RS01325	COG5444	nuclease activity
ETK69_RS01345	COG0457	Tetratricopeptide repeat
ETK69_RS01360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETK69_RS01395	COG0738	Major facilitator superfamily
ETK69_RS01400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS01410	COG1063	alcohol dehydrogenase
ETK69_RS01415	COG0659	secondary active sulfate transmembrane transporter activity
ETK69_RS01420	COG0385	Bile acid
ETK69_RS01425	COG2819	hydrolase of the alpha beta superfamily
ETK69_RS01430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS01435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS01440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETK69_RS01445	COG2207	Transcriptional regulator
ETK69_RS01445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETK69_RS01450	COG3876	Protein conserved in bacteria
ETK69_RS01455	COG1472	Belongs to the glycosyl hydrolase 3 family
ETK69_RS01460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETK69_RS01465	COG1263	PTS System
ETK69_RS01465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS01475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETK69_RS01480	COG1683	Conserved Protein
ETK69_RS01510	COG1595	DNA-templated transcription, initiation
ETK69_RS01515	COG5662	AntiSigma factor
ETK69_RS01520	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETK69_RS01525	COG4856	YbbR-like protein
ETK69_RS01565	COG1063	alcohol dehydrogenase
ETK69_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS01615	COG1346	cytolysis
ETK69_RS01620	COG1380	Effector of murein hydrolase LrgA
ETK69_RS01625	COG1846	Transcriptional regulator
ETK69_RS01630	COG1113	amino acid transport
ETK69_RS01635	COG1011	Hydrolase
ETK69_RS01640	COG4585	Histidine kinase
ETK69_RS01645	COG2197	response regulator
ETK69_RS01650	COG1131	(ABC) transporter
ETK69_RS01690	COG0531	amino acid
ETK69_RS01715	COG0584	glycerophosphoryl diester phosphodiesterase
ETK69_RS01720	COG2271	Major facilitator Superfamily
ETK69_RS01735	COG2368	4-hydroxyphenylacetate
ETK69_RS01745	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS01760	COG0371	Dehydrogenase
ETK69_RS01770	COG1183	phosphatidylcholine synthase activity
ETK69_RS01775	COG0586	Pfam SNARE associated Golgi protein
ETK69_RS01780	COG0688	phosphatidylethanolamine metabolic process
ETK69_RS01795	COG1301	dicarboxylic acid transport
ETK69_RS01800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS01805	COG0833	amino acid
ETK69_RS01810	COG2040	homocysteine
ETK69_RS01815	COG1115	amino acid carrier protein
ETK69_RS01820	COG2066	Belongs to the glutaminase family
ETK69_RS01825	COG4191	Histidine kinase
ETK69_RS01830	COG0784	Response regulator, receiver
ETK69_RS01835	COG3173	Aminoglycoside phosphotransferase
ETK69_RS01855	COG3773	Cell wall hydrolase
ETK69_RS01865	COG3540	Alkaline phosphatase
ETK69_RS01870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETK69_RS01875	COG0805	protein transport
ETK69_RS01885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETK69_RS01890	COG0477	Major facilitator Superfamily
ETK69_RS01895	COG1309	transcriptional regulator
ETK69_RS01900	COG0252	asparaginase activity
ETK69_RS01905	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETK69_RS01910	COG3012	SEC-C Motif Domain Protein
ETK69_RS01910	COG1405	negative regulation of cell septum assembly
ETK69_RS01915	COG0667	Aldo Keto reductase
ETK69_RS01925	COG1595	DNA-templated transcription, initiation
ETK69_RS01930	COG1595	DNA-templated transcription, initiation
ETK69_RS01935	COG1876	peptidase activity
ETK69_RS01940	COG0457	Tetratricopeptide repeat
ETK69_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS01965	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETK69_RS01970	COG1121	(ABC) transporter
ETK69_RS01975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETK69_RS01980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS01985	COG2310	stress, protein
ETK69_RS01990	COG2310	stress, protein
ETK69_RS01995	COG2310	stress, protein
ETK69_RS02000	COG0861	Integral membrane protein TerC family
ETK69_RS02010	COG3853	Toxic anion resistance protein (TelA)
ETK69_RS02015	COG0477	Major facilitator Superfamily
ETK69_RS02020	COG4175	Glycine betaine
ETK69_RS02020	COG0517	IMP dehydrogenase activity
ETK69_RS02025	COG4176	ABC-type proline glycine betaine transport system permease component
ETK69_RS02030	COG2113	Glycine betaine
ETK69_RS02035	COG1473	amidohydrolase
ETK69_RS02040	COG1288	antiporter activity
ETK69_RS02050	COG0366	Alpha amylase catalytic
ETK69_RS02060	COG2814	Major facilitator Superfamily
ETK69_RS02065	COG1846	Transcriptional regulator
ETK69_RS02070	COG1280	lysine exporter protein (LysE YggA)
ETK69_RS02075	COG3403	YqcI/YcgG family
ETK69_RS02080	COG1113	amino acid transport
ETK69_RS02085	COG3665	Urea carboxylase-associated protein
ETK69_RS02100	COG1660	Displays ATPase and GTPase activities
ETK69_RS02110	COG2271	Major facilitator Superfamily
ETK69_RS02115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETK69_RS02120	COG3458	cephalosporin-C deacetylase activity
ETK69_RS02125	COG3541	Predicted nucleotidyltransferase
ETK69_RS02130	COG0506	proline dehydrogenase activity
ETK69_RS02135	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS02140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETK69_RS02145	COG2508	Transcriptional regulator
ETK69_RS02155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETK69_RS02155	COG1587	Uroporphyrinogen-III synthase
ETK69_RS02160	COG2146	nitrite reductase [NAD(P)H] activity
ETK69_RS02165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETK69_RS02170	COG0243	molybdopterin cofactor binding
ETK69_RS02175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETK69_RS02180	COG2223	nitrite transmembrane transporter activity
ETK69_RS02185	COG0523	cobalamin synthesis protein
ETK69_RS02190	COG1063	alcohol dehydrogenase
ETK69_RS02195	COG1714	RDD family
ETK69_RS02205	COG2723	6-phospho-beta-galactosidase activity
ETK69_RS02215	COG3209	COG3209 Rhs family protein
ETK69_RS02220	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ETK69_RS02225	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ETK69_RS02230	COG1733	regulation of RNA biosynthetic process
ETK69_RS02235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS02240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS02245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS02250	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ETK69_RS02265	COG2364	Membrane
ETK69_RS02270	COG1126	abc transporter atp-binding protein
ETK69_RS02275	COG0765	amino acid transport
ETK69_RS02280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS02285	COG0583	DNA-binding transcription factor activity
ETK69_RS02290	COG0163	prenyltransferase activity
ETK69_RS02295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ETK69_RS02310	COG3104	oligopeptide transport
ETK69_RS02315	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS02325	COG0697	spore germination
ETK69_RS02335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETK69_RS02340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS02345	COG0456	acetyltransferase
ETK69_RS02350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS02355	COG0765	amino acid transport
ETK69_RS02360	COG1126	abc transporter atp-binding protein
ETK69_RS02365	COG1473	amidohydrolase
ETK69_RS02370	COG2079	MmgE PrpD family protein
ETK69_RS02375	COG1136	(ABC) transporter
ETK69_RS02380	COG0577	efflux transmembrane transporter activity
ETK69_RS02385	COG0745	RESPONSE REGULATOR receiver
ETK69_RS02390	COG5002	protein histidine kinase activity
ETK69_RS02390	COG3850	Histidine kinase
ETK69_RS02395	COG0457	Tetratricopeptide repeat
ETK69_RS02410	COG0527	aspartate kinase activity
ETK69_RS02415	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS02420	COG4605	iron ion homeostasis
ETK69_RS02425	COG4604	ABC transporter, ATP-binding protein
ETK69_RS02430	COG4607	ABC-type enterochelin transport system periplasmic component
ETK69_RS02435	COG2814	Major facilitator Superfamily
ETK69_RS02440	COG1309	transcriptional regulator
ETK69_RS02445	COG0778	Nitroreductase
ETK69_RS02450	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETK69_RS02455	COG0640	Transcriptional regulator
ETK69_RS02460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETK69_RS02465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS02470	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS02475	COG4975	Glucose uptake
ETK69_RS02480	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS02485	COG4549	nuclear export factor GLE1
ETK69_RS02490	COG2372	response to copper ion
ETK69_RS02490	COG1276	copper resistance
ETK69_RS02495	COG1349	DNA-binding transcription factor activity
ETK69_RS02505	COG2213	PTS system mannitol-specific
ETK69_RS02510	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETK69_RS02530	COG0561	phosphatase activity
ETK69_RS02540	COG1914	H( )-stimulated, divalent metal cation uptake system
ETK69_RS02550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETK69_RS02560	COG1414	Transcriptional regulator
ETK69_RS02565	COG2755	lipolytic protein G-D-S-L family
ETK69_RS02575	COG2329	Antibiotic biosynthesis monooxygenase
ETK69_RS02580	COG0768	penicillin binding
ETK69_RS02585	COG4989	oxidoreductase activity
ETK69_RS02590	COG3711	transcriptional antiterminator
ETK69_RS02595	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS02600	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS02605	COG1917	Cupin 2, conserved barrel domain protein
ETK69_RS02610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETK69_RS02615	COG3871	stress protein (general stress protein 26)
ETK69_RS02625	COG2814	Major facilitator Superfamily
ETK69_RS02630	COG1522	sequence-specific DNA binding
ETK69_RS02635	COG0551	DNA topoisomerase type I activity
ETK69_RS02635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETK69_RS02640	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ETK69_RS02645	COG3706	GGDEF domain
ETK69_RS02650	COG5298	Protein conserved in bacteria
ETK69_RS02655	COG1215	transferase activity, transferring glycosyl groups
ETK69_RS02665	COG0531	amino acid
ETK69_RS02670	COG0494	nUDIX hydrolase
ETK69_RS02675	COG0028	Belongs to the TPP enzyme family
ETK69_RS02680	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS02680	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS02680	COG1388	LysM domain
ETK69_RS02700	COG0457	Tetratricopeptide repeat
ETK69_RS02730	COG1914	H( )-stimulated, divalent metal cation uptake system
ETK69_RS02745	COG4876	unkown
ETK69_RS02755	COG2076	Multidrug Resistance protein
ETK69_RS02760	COG2217	Heavy metal translocating P-type atpase
ETK69_RS02765	COG3729	General stress protein
ETK69_RS02770	COG0662	Cupin 2, conserved barrel domain protein
ETK69_RS02775	COG2329	Antibiotic biosynthesis monooxygenase
ETK69_RS02780	COG3546	catalase activity
ETK69_RS02785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ETK69_RS02790	COG3290	protein histidine kinase activity
ETK69_RS02795	COG4565	transcriptional regulatory protein
ETK69_RS02800	COG1301	dicarboxylic acid transport
ETK69_RS02805	COG0628	permease
ETK69_RS02810	COG1131	(ABC) transporter
ETK69_RS02815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETK69_RS02825	COG1960	acyl-CoA dehydrogenase activity
ETK69_RS02840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETK69_RS02845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS02855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETK69_RS02860	COG0513	Belongs to the DEAD box helicase family
ETK69_RS02865	COG3402	PFAM membrane-flanked domain
ETK69_RS02870	COG3428	Bacterial PH domain
ETK69_RS02875	COG0705	Rhomboid family
ETK69_RS02885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ETK69_RS02890	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETK69_RS02895	COG0864	Transcriptional regulator
ETK69_RS02900	COG2337	Toxic component of a toxin-antitoxin (TA) module
ETK69_RS02905	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS02910	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS02915	COG2172	sigma factor antagonist activity
ETK69_RS02920	COG2208	phosphoserine phosphatase activity
ETK69_RS02925	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS02935	COG1191	sigma factor activity
ETK69_RS02940	COG2208	phosphoserine phosphatase activity
ETK69_RS02945	COG2183	response to ionizing radiation
ETK69_RS02995	COG0582	viral genome integration into host DNA
ETK69_RS03000	COG2856	Zn peptidase
ETK69_RS03005	COG1396	sequence-specific DNA binding
ETK69_RS03025	COG1674	ftsk spoiiie
ETK69_RS03030	COG2946	Replication initiation factor
ETK69_RS03085	COG0433	COG0433 Predicted ATPase
ETK69_RS03095	COG5644	endopeptidase inhibitor activity
ETK69_RS03100	COG0791	NLP P60 protein
ETK69_RS03100	COG0741	lytic transglycosylase activity
ETK69_RS03120	COG0457	Tetratricopeptide repeat
ETK69_RS03125	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETK69_RS03135	COG0477	Major facilitator Superfamily
ETK69_RS03155	COG2030	dehydratase
ETK69_RS03170	COG1959	2 iron, 2 sulfur cluster binding
ETK69_RS03175	COG2910	NAD(P)H-binding
ETK69_RS03185	COG1309	transcriptional regulator
ETK69_RS03190	COG3239	Fatty acid desaturase
ETK69_RS03200	COG1278	Cold shock
ETK69_RS03205	COG1329	Transcriptional regulator
ETK69_RS03210	COG1794	racemase activity, acting on amino acids and derivatives
ETK69_RS03225	COG3621	Patatin-like phospholipase
ETK69_RS03235	COG0662	Cupin 2, conserved barrel domain protein
ETK69_RS03250	COG0277	FAD linked oxidase domain protein
ETK69_RS03275	COG0662	Cupin 2, conserved barrel domain protein
ETK69_RS03280	COG2318	DinB family
ETK69_RS03285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETK69_RS03310	COG1064	alcohol dehydrogenase
ETK69_RS03315	COG0789	Transcriptional regulator
ETK69_RS03325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETK69_RS03340	COG2814	Major facilitator Superfamily
ETK69_RS03345	COG1309	transcriptional regulator
ETK69_RS03350	COG5577	PFAM Coat F domain
ETK69_RS03360	COG1063	alcohol dehydrogenase
ETK69_RS03365	COG5577	PFAM Coat F domain
ETK69_RS03380	COG4585	Histidine kinase
ETK69_RS03385	COG2197	response regulator
ETK69_RS03390	COG2409	Drug exporters of the RND superfamily
ETK69_RS03395	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ETK69_RS03400	COG0488	(ABC) transporter
ETK69_RS03405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETK69_RS03410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS03420	COG2814	Major facilitator Superfamily
ETK69_RS03425	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETK69_RS03435	COG0730	response to heat
ETK69_RS03440	COG0456	acetyltransferase
ETK69_RS03445	COG0789	Transcriptional regulator
ETK69_RS03445	COG4978	Transcriptional regulator
ETK69_RS03450	COG0697	spore germination
ETK69_RS03455	COG1051	belongs to the nudix hydrolase family
ETK69_RS03460	COG2226	methyltransferase
ETK69_RS03465	COG0473	3-isopropylmalate dehydrogenase activity
ETK69_RS03470	COG1802	Transcriptional regulator
ETK69_RS03475	COG1819	glycosyl
ETK69_RS03490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETK69_RS03495	COG1388	LysM domain
ETK69_RS03500	COG2814	Major facilitator Superfamily
ETK69_RS03505	COG2188	Transcriptional regulator
ETK69_RS03510	COG2186	Transcriptional regulator
ETK69_RS03515	COG2807	transmembrane transport
ETK69_RS03520	COG2076	Multidrug Resistance protein
ETK69_RS03525	COG2076	Multidrug Resistance protein
ETK69_RS03530	COG1309	transcriptional regulator
ETK69_RS03535	COG0531	amino acid
ETK69_RS03545	COG3832	glyoxalase III activity
ETK69_RS03550	COG0604	alcohol dehydrogenase
ETK69_RS03560	COG2814	Major facilitator Superfamily
ETK69_RS03600	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETK69_RS03605	COG0802	atpase or kinase
ETK69_RS03610	COG1214	PFAM Peptidase M22, glycoprotease
ETK69_RS03615	COG0456	acetyltransferase
ETK69_RS03620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETK69_RS03625	COG0488	(ABC) transporter
ETK69_RS03640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETK69_RS03645	COG0805	protein transport
ETK69_RS03655	COG1266	CAAX protease self-immunity
ETK69_RS03670	COG0156	8-amino-7-oxononanoate synthase activity
ETK69_RS03690	COG3403	YqcI/YcgG family
ETK69_RS03705	COG2814	Major facilitator Superfamily
ETK69_RS03710	COG0457	Tetratricopeptide repeat
ETK69_RS03715	COG1063	alcohol dehydrogenase
ETK69_RS03720	COG2211	Major facilitator Superfamily
ETK69_RS03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETK69_RS03735	COG1842	Phage shock protein A
ETK69_RS03740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETK69_RS03745	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ETK69_RS03750	COG4260	virion core protein, lumpy skin disease virus
ETK69_RS03755	COG2755	lipolytic protein G-D-S-L family
ETK69_RS03755	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETK69_RS03765	COG1595	DNA-templated transcription, initiation
ETK69_RS03770	COG1063	alcohol dehydrogenase
ETK69_RS03775	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETK69_RS03780	COG0823	Involved in the tonB-independent uptake of proteins
ETK69_RS03795	COG2132	Multicopper oxidase
ETK69_RS03800	COG1113	amino acid transport
ETK69_RS03805	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETK69_RS03810	COG0714	Associated with various cellular activities
ETK69_RS03815	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETK69_RS03820	COG1305	Transglutaminase-like
ETK69_RS03850	COG2211	Major facilitator Superfamily
ETK69_RS03865	COG2252	PERMEase
ETK69_RS03870	COG3064	Membrane
ETK69_RS03890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETK69_RS03895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETK69_RS03900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETK69_RS03905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETK69_RS03910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETK69_RS03925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETK69_RS03935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETK69_RS03940	COG0138	bifunctional purine biosynthesis protein purh
ETK69_RS03945	COG0151	Belongs to the GarS family
ETK69_RS03955	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETK69_RS03960	COG1470	cell adhesion involved in biofilm formation
ETK69_RS03965	COG4496	protein, YerC YecD
ETK69_RS03970	COG0069	glutamate synthase activity
ETK69_RS03985	COG0210	DNA helicase
ETK69_RS03995	COG4851	CamS sex pheromone cAM373 precursor
ETK69_RS04000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETK69_RS04005	COG1285	pathogenesis
ETK69_RS04010	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETK69_RS04030	COG1309	transcriptional regulator
ETK69_RS04035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETK69_RS04040	COG1597	lipid kinase activity
ETK69_RS04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETK69_RS04050	COG2197	response regulator
ETK69_RS04060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS04070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETK69_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS04085	COG1131	(ABC) transporter
ETK69_RS04115	COG5444	nuclease activity
ETK69_RS04125	COG5444	nuclease activity
ETK69_RS04155	COG3546	catalase activity
ETK69_RS04160	COG0454	-acetyltransferase
ETK69_RS04170	COG2323	membrane
ETK69_RS04175	COG2329	Antibiotic biosynthesis monooxygenase
ETK69_RS04180	COG0346	lactoylglutathione lyase activity
ETK69_RS04190	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS04195	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ETK69_RS04200	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ETK69_RS04205	COG4208	sulfate ABC transporter
ETK69_RS04215	COG5583	Uncharacterized small protein (DUF2292)
ETK69_RS04220	COG0196	riboflavin kinase activity
ETK69_RS04225	COG0670	Belongs to the BI1 family
ETK69_RS04230	COG1846	Transcriptional regulator
ETK69_RS04235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETK69_RS04245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETK69_RS04245	COG2124	cytochrome p450
ETK69_RS04260	COG1131	(ABC) transporter
ETK69_RS04275	COG1368	sulfuric ester hydrolase activity
ETK69_RS04280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ETK69_RS04285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETK69_RS04290	COG1442	glycosyl transferase family 8
ETK69_RS04295	COG1216	Glycosyl transferase, family 2
ETK69_RS04300	COG1442	glycosyl transferase family 8
ETK69_RS04305	COG2223	nitrite transmembrane transporter activity
ETK69_RS04310	COG0531	amino acid
ETK69_RS04315	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS04320	COG0840	transmembrane signaling receptor activity
ETK69_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS04330	COG0463	Glycosyl transferase, family 2
ETK69_RS04330	COG0457	Tetratricopeptide repeat
ETK69_RS04335	COG0488	(ABC) transporter
ETK69_RS04340	COG0789	Transcriptional regulator
ETK69_RS04345	COG2814	Major facilitator Superfamily
ETK69_RS04350	COG0488	(ABC) transporter
ETK69_RS04355	COG0513	Belongs to the DEAD box helicase family
ETK69_RS04365	COG2130	NADP-dependent
ETK69_RS04380	COG3866	Pectate lyase
ETK69_RS04385	COG0471	metal ion transport
ETK69_RS04410	COG2972	Histidine kinase
ETK69_RS04410	COG0745	RESPONSE REGULATOR receiver
ETK69_RS04425	COG2851	Citrate transporter
ETK69_RS04430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS04435	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ETK69_RS04445	COG2258	MOSC domain
ETK69_RS04465	COG0024	Methionine aminopeptidase
ETK69_RS04470	COG1263	PTS System
ETK69_RS04470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS04480	COG1368	sulfuric ester hydrolase activity
ETK69_RS04490	COG0071	Belongs to the small heat shock protein (HSP20) family
ETK69_RS04505	COG1263	PTS System
ETK69_RS04505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS04510	COG0366	Alpha amylase catalytic
ETK69_RS04515	COG2188	Transcriptional regulator
ETK69_RS04520	COG0778	Nitroreductase
ETK69_RS04535	COG0737	Belongs to the 5'-nucleotidase family
ETK69_RS04540	COG0693	protein deglycase activity
ETK69_RS04545	COG1609	Transcriptional regulator
ETK69_RS04560	COG2814	Major facilitator Superfamily
ETK69_RS04570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETK69_RS04575	COG4980	gas vesicle protein
ETK69_RS04580	COG1295	ribonuclease BN
ETK69_RS04585	COG0477	Major facilitator Superfamily
ETK69_RS04590	COG0387	Pfam Sodium calcium exchanger
ETK69_RS04600	COG0668	transmembrane transport
ETK69_RS04605	COG0535	radical SAM domain protein
ETK69_RS04615	COG0726	polysaccharide deacetylase
ETK69_RS04620	COG2084	Dehydrogenase
ETK69_RS04630	COG0598	Magnesium transport protein CorA
ETK69_RS04635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETK69_RS04640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETK69_RS04650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETK69_RS04655	COG4637	Psort location Cytoplasmic, score
ETK69_RS04660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETK69_RS04665	COG0022	dehydrogenase e1 component
ETK69_RS04670	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETK69_RS04675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETK69_RS04680	COG3284	Transcriptional regulator
ETK69_RS04690	COG1486	melibiose metabolic process
ETK69_RS04695	COG1737	Transcriptional regulator
ETK69_RS04700	COG1263	PTS System
ETK69_RS04700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS04705	COG1132	(ABC) transporter
ETK69_RS04710	COG1132	(ABC) transporter
ETK69_RS04715	COG2259	Doxx family
ETK69_RS04720	COG2514	catechol 2,3-dioxygenase activity
ETK69_RS04735	COG1695	Transcriptional regulator
ETK69_RS04740	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETK69_RS04745	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ETK69_RS04750	COG0574	Belongs to the PEP-utilizing enzyme family
ETK69_RS04750	COG3848	Pyruvate phosphate dikinase
ETK69_RS04755	COG2732	(Barnase) inhibitor
ETK69_RS04760	COG2318	DinB family
ETK69_RS04765	COG2814	Major facilitator Superfamily
ETK69_RS04770	COG1846	Transcriptional regulator
ETK69_RS04775	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ETK69_RS04775	COG0392	lysyltransferase activity
ETK69_RS04780	COG0384	phenazine biosynthesis protein PhzF
ETK69_RS04785	COG0778	Nitroreductase
ETK69_RS04800	COG1090	epimerase
ETK69_RS04815	COG2814	Major facilitator Superfamily
ETK69_RS04825	COG3591	Belongs to the peptidase S1B family
ETK69_RS04840	COG3103	Sh3 type 3 domain protein
ETK69_RS04845	COG5658	integral membrane protein
ETK69_RS04850	COG0596	Alpha beta hydrolase
ETK69_RS04855	COG0463	Glycosyl transferase, family 2
ETK69_RS04860	COG4485	Bacterial membrane protein, YfhO
ETK69_RS04865	COG1988	membrane-bound metal-dependent
ETK69_RS04870	COG1194	a g-specific adenine glycosylase
ETK69_RS04880	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS04900	COG1132	(ABC) transporter
ETK69_RS04905	COG4129	membrane
ETK69_RS04915	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETK69_RS04920	COG0735	belongs to the Fur family
ETK69_RS05060	COG5577	PFAM Coat F domain
ETK69_RS05065	COG3340	Belongs to the peptidase S51 family
ETK69_RS05075	COG0277	FAD linked oxidase domain protein
ETK69_RS05085	COG0747	negative chemotaxis
ETK69_RS05090	COG0601	transmembrane transport
ETK69_RS05095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETK69_RS05100	COG0444	Belongs to the ABC transporter superfamily
ETK69_RS05105	COG4608	Belongs to the ABC transporter superfamily
ETK69_RS05110	COG0753	catalase activity
ETK69_RS05125	COG1116	anion transmembrane transporter activity
ETK69_RS05130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETK69_RS05135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETK69_RS05160	COG1476	TRANSCRIPTIONal
ETK69_RS05170	COG3382	B3 4 domain protein
ETK69_RS05175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETK69_RS05185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETK69_RS05190	COG0789	Transcriptional regulator
ETK69_RS05195	COG1664	Polymer-forming cytoskeletal
ETK69_RS05200	COG1664	Polymer-forming cytoskeletal
ETK69_RS05205	COG2766	serine protein kinase
ETK69_RS05220	COG1846	Transcriptional regulator
ETK69_RS05225	COG1566	PFAM secretion protein HlyD family protein
ETK69_RS05230	COG2814	Major facilitator Superfamily
ETK69_RS05235	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETK69_RS05250	COG1725	Transcriptional regulator
ETK69_RS05255	COG1131	(ABC) transporter
ETK69_RS05260	COG1131	(ABC) transporter
ETK69_RS05265	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETK69_RS05275	COG1278	Cold shock
ETK69_RS05285	COG1464	Belongs to the NlpA lipoprotein family
ETK69_RS05290	COG3706	GGDEF domain
ETK69_RS05295	COG1823	symporter activity
ETK69_RS05315	COG5577	PFAM Coat F domain
ETK69_RS05320	COG0737	Belongs to the 5'-nucleotidase family
ETK69_RS05320	COG1525	nuclease
ETK69_RS05320	COG4085	toxin activity
ETK69_RS05325	COG3764	Sortase (surface protein transpeptidase)
ETK69_RS05330	COG0564	pseudouridine synthase activity
ETK69_RS05340	COG0517	IMP dehydrogenase activity
ETK69_RS05345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETK69_RS05350	COG3153	acetyltransferase
ETK69_RS05350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETK69_RS05360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETK69_RS05365	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ETK69_RS05370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETK69_RS05380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETK69_RS05385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETK69_RS05390	COG4585	Histidine kinase
ETK69_RS05390	COG2203	Gaf domain
ETK69_RS05395	COG2197	response regulator
ETK69_RS05400	COG0431	NADPH-dependent FMN reductase
ETK69_RS05415	COG0791	NLP P60 protein
ETK69_RS05415	COG1388	LysM domain
ETK69_RS05420	COG1959	2 iron, 2 sulfur cluster binding
ETK69_RS05430	COG0668	transmembrane transport
ETK69_RS05435	COG2719	SpoVR family
ETK69_RS05440	COG1785	Belongs to the alkaline phosphatase family
ETK69_RS05445	COG1388	LysM domain
ETK69_RS05445	COG0791	NLP P60 protein
ETK69_RS05450	COG0583	DNA-binding transcription factor activity
ETK69_RS05455	COG0372	Belongs to the citrate synthase family
ETK69_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS05465	COG0531	amino acid
ETK69_RS05470	COG0733	neurotransmitter:sodium symporter activity
ETK69_RS05485	COG1595	DNA-templated transcription, initiation
ETK69_RS05490	COG0204	Acyl-transferase
ETK69_RS05495	COG1253	flavin adenine dinucleotide binding
ETK69_RS05500	COG0789	Transcriptional regulator
ETK69_RS05505	COG0436	Aminotransferase
ETK69_RS05510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETK69_RS05515	COG1253	flavin adenine dinucleotide binding
ETK69_RS05520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETK69_RS05525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETK69_RS05530	COG0584	glycerophosphoryl diester phosphodiesterase
ETK69_RS05540	COG0668	transmembrane transport
ETK69_RS05545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETK69_RS05550	COG0726	polysaccharide deacetylase
ETK69_RS05555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS05560	COG3226	Transcriptional regulator
ETK69_RS05570	COG0589	response to stress
ETK69_RS05575	COG1132	(ABC) transporter
ETK69_RS05580	COG1132	(ABC) transporter
ETK69_RS05585	COG0702	epimerase
ETK69_RS05605	COG0189	ligase activity
ETK69_RS05610	COG0189	ligase activity
ETK69_RS05625	COG4335	DNA alkylation repair
ETK69_RS05630	COG0561	phosphatase activity
ETK69_RS05635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETK69_RS05645	COG0475	glutathione-regulated potassium exporter activity
ETK69_RS05650	COG0490	domain, Protein
ETK69_RS05660	COG1024	Enoyl-CoA hydratase
ETK69_RS05670	COG4152	abc transporter atp-binding protein
ETK69_RS05675	COG1668	transmembrane transport
ETK69_RS05680	COG0420	3'-5' exonuclease activity
ETK69_RS05685	COG4717	serine-type aminopeptidase activity
ETK69_RS05700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETK69_RS05740	COG4980	gas vesicle protein
ETK69_RS05755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETK69_RS05760	COG0537	adenosine 5'-monophosphoramidase activity
ETK69_RS05765	COG1131	(ABC) transporter
ETK69_RS05770	COG4473	ABC transporter
ETK69_RS05780	COG1473	amidohydrolase
ETK69_RS05785	COG3069	C4-dicarboxylate transmembrane transporter activity
ETK69_RS05790	COG2329	Antibiotic biosynthesis monooxygenase
ETK69_RS05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETK69_RS05805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETK69_RS05810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ETK69_RS05815	COG1309	transcriptional regulator
ETK69_RS05820	COG1511	domain protein
ETK69_RS05825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETK69_RS05835	COG1363	Peptidase, m42
ETK69_RS05840	COG1301	dicarboxylic acid transport
ETK69_RS05850	COG1234	tRNA 3'-trailer cleavage
ETK69_RS05855	COG0095	Lipoate-protein ligase
ETK69_RS05860	COG0702	epimerase
ETK69_RS05865	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS05875	COG0501	Belongs to the peptidase M48B family
ETK69_RS05880	COG1404	Belongs to the peptidase S8 family
ETK69_RS05895	COG0406	alpha-ribazole phosphatase activity
ETK69_RS05900	COG0183	Belongs to the thiolase family
ETK69_RS05905	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS05910	COG1268	BioY protein
ETK69_RS05915	COG0840	transmembrane signaling receptor activity
ETK69_RS05920	COG0723	plastoquinol--plastocyanin reductase activity
ETK69_RS05920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETK69_RS05925	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS05935	COG4903	ComK protein
ETK69_RS05945	COG5646	InterPro IPR014922
ETK69_RS05970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETK69_RS05985	COG0398	Pfam SNARE associated Golgi protein
ETK69_RS05990	COG0681	Belongs to the peptidase S26 family
ETK69_RS05995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETK69_RS06000	COG1846	Transcriptional regulator
ETK69_RS06005	COG3180	Ammonia monooxygenase
ETK69_RS06010	COG2814	Major facilitator Superfamily
ETK69_RS06020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ETK69_RS06025	COG2323	membrane
ETK69_RS06040	COG0420	3'-5' exonuclease activity
ETK69_RS06045	COG0419	ATPase involved in DNA repair
ETK69_RS06050	COG1403	HNH endonuclease
ETK69_RS06090	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETK69_RS06105	COG0367	asparagine synthase
ETK69_RS06110	COG1562	ergosterol biosynthetic process
ETK69_RS06115	COG0534	Mate efflux family protein
ETK69_RS06120	COG1917	Cupin 2, conserved barrel domain protein
ETK69_RS06120	COG2207	Transcriptional regulator
ETK69_RS06125	COG1609	Transcriptional regulator
ETK69_RS06130	COG0673	inositol 2-dehydrogenase activity
ETK69_RS06135	COG2318	DinB family
ETK69_RS06140	COG1279	arginine transmembrane transporter activity
ETK69_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETK69_RS06150	COG1357	PFAM Pentapeptide repeats (8 copies)
ETK69_RS06155	COG2153	protein acetylation
ETK69_RS06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETK69_RS06160	COG0646	methionine synthase
ETK69_RS06170	COG2996	Protein conserved in bacteria
ETK69_RS06175	COG1744	ABC transporter substrate-binding protein PnrA-like
ETK69_RS06180	COG0840	transmembrane signaling receptor activity
ETK69_RS06185	COG2124	cytochrome p450
ETK69_RS06195	COG1307	EDD domain protein, DegV family
ETK69_RS06200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS06215	COG0561	phosphatase activity
ETK69_RS06220	COG1073	alpha beta
ETK69_RS06225	COG2151	metal-sulfur cluster biosynthetic enzyme
ETK69_RS06235	COG0277	FAD linked oxidase domain protein
ETK69_RS06240	COG2271	Major facilitator Superfamily
ETK69_RS06250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETK69_RS06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETK69_RS06265	COG0505	Belongs to the CarA family
ETK69_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETK69_RS06275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETK69_RS06310	COG1744	ABC transporter substrate-binding protein PnrA-like
ETK69_RS06325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETK69_RS06330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETK69_RS06335	COG5504	Zn-dependent protease
ETK69_RS06340	COG0444	Belongs to the ABC transporter superfamily
ETK69_RS06345	COG4608	Belongs to the ABC transporter superfamily
ETK69_RS06355	COG0601	transmembrane transport
ETK69_RS06360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETK69_RS06370	COG0180	Tryptophanyl-tRNA synthetase
ETK69_RS06375	COG4166	transmembrane transport
ETK69_RS06380	COG0601	transmembrane transport
ETK69_RS06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETK69_RS06390	COG0444	Belongs to the ABC transporter superfamily
ETK69_RS06395	COG4608	Belongs to the ABC transporter superfamily
ETK69_RS06405	COG0456	acetyltransferase
ETK69_RS06410	COG1393	Belongs to the ArsC family
ETK69_RS06415	COG0861	Integral membrane protein TerC family
ETK69_RS06420	COG4862	establishment of competence for transformation
ETK69_RS06425	COG4469	Competence protein
ETK69_RS06430	COG1164	Oligoendopeptidase f
ETK69_RS06435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETK69_RS06440	COG2346	COG2346, Truncated hemoglobins
ETK69_RS06445	COG0741	lytic transglycosylase activity
ETK69_RS06450	COG4116	CYTH
ETK69_RS06460	COG2357	RelA SpoT domain protein
ETK69_RS06465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETK69_RS06470	COG0564	pseudouridine synthase activity
ETK69_RS06480	COG0569	domain protein
ETK69_RS06480	COG0475	glutathione-regulated potassium exporter activity
ETK69_RS06485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETK69_RS06490	COG0352	thiamine-phosphate diphosphorylase activity
ETK69_RS06495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETK69_RS06500	COG2104	thiamine diphosphate biosynthetic process
ETK69_RS06510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETK69_RS06515	COG0351	phosphomethylpyrimidine kinase
ETK69_RS06520	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETK69_RS06575	COG0210	DNA helicase
ETK69_RS06595	COG1131	(ABC) transporter
ETK69_RS06605	COG2153	protein acetylation
ETK69_RS06615	COG2382	esterase
ETK69_RS06620	COG0626	cystathionine gamma-synthase activity
ETK69_RS06625	COG0626	cystathionine gamma-synthase activity
ETK69_RS06680	COG1484	DNA-dependent DNA replication
ETK69_RS06705	COG3655	Transcriptional regulator
ETK69_RS06740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS06740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS06780	COG1780	Probably involved in ribonucleotide reductase function
ETK69_RS06785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETK69_RS06790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETK69_RS06795	COG0756	dUTP diphosphatase activity
ETK69_RS06805	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ETK69_RS06810	COG3584	3D domain protein
ETK69_RS06850	COG1793	dna ligase
ETK69_RS06905	COG0582	viral genome integration into host DNA
ETK69_RS06990	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETK69_RS07000	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS07020	COG4824	toxin secretion phage lysis holin
ETK69_RS07025	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS07025	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS07060	COG0582	viral genome integration into host DNA
ETK69_RS07160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETK69_RS07215	COG3328	transposase activity
ETK69_RS07290	COG5444	nuclease activity
ETK69_RS07320	COG2367	Beta-lactamase
ETK69_RS07325	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETK69_RS07330	COG0477	Major facilitator Superfamily
ETK69_RS07335	COG1846	Transcriptional regulator
ETK69_RS07345	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETK69_RS07350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETK69_RS07355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ETK69_RS07360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS07360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS07365	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETK69_RS07395	COG1285	pathogenesis
ETK69_RS07410	COG2205	protein histidine kinase activity
ETK69_RS07420	COG3383	formate dehydrogenase (NAD+) activity
ETK69_RS07425	COG2427	Protein of unknown function (DUF1641)
ETK69_RS07430	COG2124	cytochrome p450
ETK69_RS07445	COG1587	Uroporphyrinogen-III synthase
ETK69_RS07450	COG0390	transport system, permease component
ETK69_RS07455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETK69_RS07460	COG0697	spore germination
ETK69_RS07465	COG4297	protein containing double-stranded beta helix domain
ETK69_RS07475	COG1252	NADH dehydrogenase
ETK69_RS07490	COG1609	Transcriptional regulator
ETK69_RS07495	COG0246	Mannitol dehydrogenase
ETK69_RS07500	COG2721	sulfolactate sulfo-lyase activity
ETK69_RS07505	COG0745	RESPONSE REGULATOR receiver
ETK69_RS07510	COG2205	protein histidine kinase activity
ETK69_RS07510	COG2770	Histidine kinase
ETK69_RS07530	COG4585	Histidine kinase
ETK69_RS07535	COG2197	response regulator
ETK69_RS07565	COG0730	response to heat
ETK69_RS07570	COG2318	DinB family
ETK69_RS07575	COG0457	Tetratricopeptide repeat
ETK69_RS07580	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS07580	COG1388	LysM domain
ETK69_RS07580	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS07590	COG4195	phage-related replication protein
ETK69_RS07595	COG2856	Zn peptidase
ETK69_RS07600	COG1396	sequence-specific DNA binding
ETK69_RS07610	COG1522	sequence-specific DNA binding
ETK69_RS07615	COG1484	DNA-dependent DNA replication
ETK69_RS07630	COG1595	DNA-templated transcription, initiation
ETK69_RS07635	COG4193	domain, Protein
ETK69_RS07670	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS07670	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS07685	COG0306	phosphate transporter
ETK69_RS07690	COG1392	Phosphate transport regulator
ETK69_RS07695	COG0531	amino acid
ETK69_RS07700	COG0346	lactoylglutathione lyase activity
ETK69_RS07705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETK69_RS07710	COG0463	Glycosyl transferase, family 2
ETK69_RS07715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETK69_RS07720	COG0477	Major facilitator Superfamily
ETK69_RS07725	COG2362	D-Aminopeptidase
ETK69_RS07730	COG0601	transmembrane transport
ETK69_RS07735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETK69_RS07740	COG0444	Belongs to the ABC transporter superfamily
ETK69_RS07745	COG4166	transmembrane transport
ETK69_RS07750	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETK69_RS07755	COG4948	Mandelate Racemase Muconate Lactonizing
ETK69_RS07760	COG0791	NLP P60 protein
ETK69_RS07765	COG4608	Belongs to the ABC transporter superfamily
ETK69_RS07770	COG2706	6-phosphogluconolactonase activity
ETK69_RS07775	COG1834	amidinotransferase
ETK69_RS07780	COG1607	acyl-coa hydrolase
ETK69_RS07785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETK69_RS07790	COG2076	Multidrug Resistance protein
ETK69_RS07795	COG2076	Multidrug Resistance protein
ETK69_RS07800	COG0788	formyltetrahydrofolate deformylase activity
ETK69_RS07805	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETK69_RS07815	COG1764	response to oxidative stress
ETK69_RS07820	COG1846	Transcriptional regulator
ETK69_RS07825	COG1764	response to oxidative stress
ETK69_RS07840	COG0457	Tetratricopeptide repeat
ETK69_RS07840	COG0463	Glycosyl transferase, family 2
ETK69_RS07850	COG2814	Major facilitator Superfamily
ETK69_RS07855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETK69_RS07865	COG1404	Belongs to the peptidase S8 family
ETK69_RS07870	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS07875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETK69_RS07880	COG1122	ATPase activity
ETK69_RS07885	COG4721	ABC-type cobalt transport system, permease component
ETK69_RS07890	COG3858	chitin binding
ETK69_RS07890	COG1388	LysM domain
ETK69_RS07910	COG2239	Acts as a magnesium transporter
ETK69_RS07915	COG0789	Transcriptional regulator
ETK69_RS07930	COG1846	Transcriptional regulator
ETK69_RS07935	COG0726	polysaccharide deacetylase
ETK69_RS07940	COG1793	dna ligase
ETK69_RS07940	COG3285	dna ligase
ETK69_RS07945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ETK69_RS07950	COG0586	Pfam SNARE associated Golgi protein
ETK69_RS07955	COG0861	Integral membrane protein TerC family
ETK69_RS07960	COG1191	sigma factor activity
ETK69_RS07985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETK69_RS07990	COG2323	membrane
ETK69_RS08000	COG3594	Acyltransferase
ETK69_RS08005	COG5002	protein histidine kinase activity
ETK69_RS08010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETK69_RS08025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETK69_RS08030	COG0436	Aminotransferase
ETK69_RS08060	COG3852	Histidine kinase
ETK69_RS08065	COG1846	Transcriptional regulator
ETK69_RS08070	COG1360	Flagellar Motor Protein
ETK69_RS08075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETK69_RS08080	COG0542	response to heat
ETK69_RS08090	COG3949	Membrane
ETK69_RS08105	COG0720	synthase
ETK69_RS08110	COG0602	queuosine metabolic process
ETK69_RS08115	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETK69_RS08120	COG1733	regulation of RNA biosynthetic process
ETK69_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08145	COG4873	Protein conserved in bacteria
ETK69_RS08155	COG3773	Cell wall hydrolase
ETK69_RS08160	COG2244	polysaccharide biosynthetic process
ETK69_RS08165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS08170	COG2217	Heavy metal translocating P-type atpase
ETK69_RS08175	COG0006	proline dipeptidase activity
ETK69_RS08180	COG1609	Transcriptional regulator
ETK69_RS08185	COG3711	transcriptional antiterminator
ETK69_RS08190	COG1263	PTS System
ETK69_RS08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS08190	COG2190	(PTS) system
ETK69_RS08195	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS08200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETK69_RS08210	COG1533	DNA photolyase activity
ETK69_RS08215	COG0840	transmembrane signaling receptor activity
ETK69_RS08220	COG2084	Dehydrogenase
ETK69_RS08225	COG2340	Cysteine-rich secretory protein family
ETK69_RS08230	COG0768	penicillin binding
ETK69_RS08235	COG4191	Histidine kinase
ETK69_RS08240	COG0436	Aminotransferase
ETK69_RS08250	COG0835	chemotaxis
ETK69_RS08250	COG0784	Response regulator, receiver
ETK69_RS08260	COG2814	Major facilitator Superfamily
ETK69_RS08265	COG1376	ErfK ybiS ycfS ynhG family protein
ETK69_RS08270	COG1408	metallophosphoesterase
ETK69_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08285	COG2200	EAL domain
ETK69_RS08290	COG4703	Protein of unknown function (DUF1797)
ETK69_RS08295	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ETK69_RS08305	COG0517	IMP dehydrogenase activity
ETK69_RS08310	COG0583	DNA-binding transcription factor activity
ETK69_RS08315	COG0716	FMN binding
ETK69_RS08325	COG0716	FMN binding
ETK69_RS08345	COG0668	transmembrane transport
ETK69_RS08350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS08370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETK69_RS08375	COG0303	'Molybdopterin
ETK69_RS08380	COG1763	Mo-molybdopterin cofactor biosynthetic process
ETK69_RS08385	COG0314	molybdopterin synthase activity
ETK69_RS08390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ETK69_RS08400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETK69_RS08405	COG1136	(ABC) transporter
ETK69_RS08410	COG0577	efflux transmembrane transporter activity
ETK69_RS08415	COG1349	DNA-binding transcription factor activity
ETK69_RS08420	COG1105	Belongs to the carbohydrate kinase PfkB family
ETK69_RS08425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS08425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETK69_RS08425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETK69_RS08430	COG0681	Belongs to the peptidase S26 family
ETK69_RS08440	COG0488	(ABC) transporter
ETK69_RS08445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETK69_RS08450	COG2309	aminopeptidase activity
ETK69_RS08460	COG1077	Cell shape determining protein MreB Mrl
ETK69_RS08470	COG2002	toxin-antitoxin pair type II binding
ETK69_RS08475	COG3852	Histidine kinase
ETK69_RS08480	COG2105	PFAM AIG2 family protein
ETK69_RS08480	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ETK69_RS08485	COG0569	domain protein
ETK69_RS08495	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETK69_RS08505	COG0561	phosphatase activity
ETK69_RS08510	COG0242	peptide deformylase activity
ETK69_RS08520	COG0497	DNA recombination
ETK69_RS08535	COG4221	oxidoreductase activity
ETK69_RS08535	COG3321	synthase
ETK69_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS08540	COG4221	oxidoreductase activity
ETK69_RS08540	COG3321	synthase
ETK69_RS08540	COG0300	oxidoreductase activity
ETK69_RS08540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS08545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08545	COG3321	synthase
ETK69_RS08545	COG4221	oxidoreductase activity
ETK69_RS08550	COG3321	synthase
ETK69_RS08550	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS08550	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS08550	COG0300	oxidoreductase activity
ETK69_RS08555	COG0300	oxidoreductase activity
ETK69_RS08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS08555	COG3321	synthase
ETK69_RS08555	COG4221	oxidoreductase activity
ETK69_RS08560	COG4221	oxidoreductase activity
ETK69_RS08560	COG0300	oxidoreductase activity
ETK69_RS08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS08560	COG3321	synthase
ETK69_RS08565	COG4221	oxidoreductase activity
ETK69_RS08565	COG3321	synthase
ETK69_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS08565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS08570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETK69_RS08575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETK69_RS08580	COG0022	dehydrogenase e1 component
ETK69_RS08585	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETK69_RS08590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETK69_RS08595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS08610	COG1982	Orn Lys Arg decarboxylase major
ETK69_RS08635	COG0483	inositol monophosphate 1-phosphatase activity
ETK69_RS08645	COG3227	Zinc metalloprotease (Elastase)
ETK69_RS08660	COG1595	DNA-templated transcription, initiation
ETK69_RS08680	COG1217	gtp-binding protein TYPA
ETK69_RS08690	COG4896	Protein conserved in bacteria
ETK69_RS08700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETK69_RS08705	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETK69_RS08710	COG2066	Belongs to the glutaminase family
ETK69_RS08720	COG0772	Belongs to the SEDS family
ETK69_RS08725	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETK69_RS08740	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETK69_RS08740	COG2010	Cytochrome c
ETK69_RS08745	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETK69_RS08750	COG1845	cytochrome c oxidase, subunit III
ETK69_RS08755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETK69_RS08760	COG3336	cytochrome c oxidase
ETK69_RS08770	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETK69_RS08775	COG2340	Cysteine-rich secretory protein family
ETK69_RS08790	COG3679	Belongs to the UPF0342 family
ETK69_RS08805	COG0742	ribosomal rna small subunit methyltransferase
ETK69_RS08815	COG3314	Sporulation integral membrane protein YlbJ
ETK69_RS08820	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETK69_RS08825	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETK69_RS08835	COG1399	metal-binding, possibly nucleic acid-binding protein
ETK69_RS08855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETK69_RS08875	COG4839	cell division protein FtsL
ETK69_RS08880	COG0768	penicillin binding
ETK69_RS08885	COG0768	penicillin binding
ETK69_RS08905	COG0772	Belongs to the SEDS family
ETK69_RS08920	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ETK69_RS08925	COG0849	cell division
ETK69_RS08930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ETK69_RS08935	COG1404	Belongs to the peptidase S8 family
ETK69_RS08935	COG4412	M6 family metalloprotease domain protein
ETK69_RS08945	COG1191	sigma factor activity
ETK69_RS08950	COG1191	sigma factor activity
ETK69_RS08955	COG1119	ATPase activity
ETK69_RS08960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETK69_RS08965	COG1873	PFAM PRC-barrel domain
ETK69_RS08970	COG1496	oxidoreductase activity
ETK69_RS08975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETK69_RS08985	COG0762	integral membrane protein
ETK69_RS08990	COG2302	S4 RNA-binding domain
ETK69_RS08995	COG3599	regulation of cell shape
ETK69_RS09005	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETK69_RS09010	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETK69_RS09020	COG0564	pseudouridine synthase activity
ETK69_RS09030	COG2233	PERMEase
ETK69_RS09040	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETK69_RS09045	COG0505	Belongs to the CarA family
ETK69_RS09050	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETK69_RS09065	COG0284	orotidine-5'-phosphate decarboxylase activity
ETK69_RS09070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETK69_RS09080	COG0306	phosphate transporter
ETK69_RS09095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETK69_RS09100	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ETK69_RS09105	COG1648	precorrin-2 dehydrogenase activity
ETK69_RS09120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETK69_RS09125	COG1561	YicC-like family, N-terminal region
ETK69_RS09135	COG0194	GDP metabolic process
ETK69_RS09145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETK69_RS09150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETK69_RS09155	COG0242	peptide deformylase activity
ETK69_RS09165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETK69_RS09165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETK69_RS09175	COG0631	protein serine/threonine phosphatase activity
ETK69_RS09180	COG0515	serine threonine protein kinase
ETK69_RS09180	COG2815	serine threonine protein kinase
ETK69_RS09190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETK69_RS09195	COG1564	THIamine pyrophosphokinase
ETK69_RS09210	COG1302	Protein conserved in bacteria
ETK69_RS09215	COG1461	Dihydroxyacetone kinase
ETK69_RS09220	COG1760	l-serine dehydratase
ETK69_RS09225	COG1760	l-serine dehydratase
ETK69_RS09230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETK69_RS09245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETK69_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS09265	COG1196	nuclear chromosome segregation
ETK69_RS09270	COG0552	protein localization to endoplasmic reticulum
ETK69_RS09285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETK69_RS09295	COG1837	Belongs to the UPF0109 family
ETK69_RS09320	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETK69_RS09335	COG2257	FlhB HrpN YscU SpaS Family
ETK69_RS09345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETK69_RS09350	COG0758	DNA mediated transformation
ETK69_RS09355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETK69_RS09365	COG4974	Belongs to the 'phage' integrase family
ETK69_RS09385	COG1815	bacterial-type flagellum-dependent cell motility
ETK69_RS09390	COG1558	bacterial-type flagellum-dependent cell motility
ETK69_RS09395	COG1677	Flagellar hook-basal body complex protein FliE
ETK69_RS09400	COG1766	The M ring may be actively involved in energy transduction
ETK69_RS09405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETK69_RS09410	COG1317	bacterial-type flagellum organization
ETK69_RS09415	COG1157	protein secretion by the type III secretion system
ETK69_RS09420	COG2882	bacterial-type flagellum organization
ETK69_RS09425	COG3334	PFAM MgtE intracellular
ETK69_RS09430	COG3144	bacterial-type flagellum assembly
ETK69_RS09435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETK69_RS09440	COG4786	Flagellar basal body rod
ETK69_RS09445	COG1582	Flagellar protein (FlbD)
ETK69_RS09450	COG1580	Controls the rotational direction of flagella during chemotaxis
ETK69_RS09455	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETK69_RS09460	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETK69_RS09460	COG1776	CheC inhibitor of MCP methylation
ETK69_RS09465	COG2201	protein-glutamate methylesterase activity
ETK69_RS09470	COG3190	flagellar
ETK69_RS09475	COG1338	Plays a role in the flagellum-specific transport system
ETK69_RS09480	COG1987	bacterial-type flagellum assembly
ETK69_RS09485	COG1684	flagellar biosynthetic protein fliR
ETK69_RS09490	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETK69_RS09495	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETK69_RS09500	COG1419	protein localization to endoplasmic reticulum
ETK69_RS09505	COG0455	bacterial-type flagellum organization
ETK69_RS09510	COG2201	protein-glutamate methylesterase activity
ETK69_RS09515	COG0643	Histidine kinase
ETK69_RS09515	COG2198	Histidine kinase
ETK69_RS09520	COG0835	chemotaxis
ETK69_RS09525	COG1776	CheC inhibitor of MCP methylation
ETK69_RS09535	COG1191	sigma factor activity
ETK69_RS09565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETK69_RS09570	COG4589	Belongs to the CDS family
ETK69_RS09580	COG0750	zinc metalloprotease
ETK69_RS09590	COG2176	DNA-directed DNA polymerase activity
ETK69_RS09600	COG0195	Participates in both transcription termination and antitermination
ETK69_RS09605	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETK69_RS09610	COG1358	cellular component organization or biogenesis
ETK69_RS09620	COG1550	Protein conserved in bacteria
ETK69_RS09635	COG0196	riboflavin kinase activity
ETK69_RS09650	COG0726	polysaccharide deacetylase
ETK69_RS09655	COG0612	Peptidase, M16
ETK69_RS09660	COG1873	PFAM PRC-barrel domain
ETK69_RS09665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETK69_RS09670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETK69_RS09675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETK69_RS09680	COG0527	aspartate kinase activity
ETK69_RS09690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETK69_RS09695	COG0740	serine-type endopeptidase activity
ETK69_RS09705	COG1674	ftsk spoiiie
ETK69_RS09705	COG4980	gas vesicle protein
ETK69_RS09710	COG2188	Transcriptional regulator
ETK69_RS09715	COG2814	Major facilitator Superfamily
ETK69_RS09720	COG1846	Transcriptional regulator
ETK69_RS09725	COG2409	Drug exporters of the RND superfamily
ETK69_RS09725	COG1033	growth of symbiont in host cell
ETK69_RS09730	COG0612	Peptidase, M16
ETK69_RS09735	COG0612	Peptidase, M16
ETK69_RS09740	COG0300	oxidoreductase activity
ETK69_RS09755	COG1426	Protein conserved in bacteria
ETK69_RS09760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETK69_RS09775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETK69_RS09785	COG1692	metallophosphoesterase
ETK69_RS09790	COG2359	stage V sporulation protein S
ETK69_RS09810	COG4550	Control of competence regulator ComK, YlbF/YmcA
ETK69_RS09875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS09880	COG3425	synthase
ETK69_RS09885	COG1024	Enoyl-CoA hydratase
ETK69_RS09895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS09895	COG4221	oxidoreductase activity
ETK69_RS09895	COG3321	synthase
ETK69_RS09895	COG0300	oxidoreductase activity
ETK69_RS09915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS09915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETK69_RS09915	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETK69_RS09915	COG3321	synthase
ETK69_RS09920	COG2124	cytochrome p450
ETK69_RS09925	COG3209	COG3209 Rhs family protein
ETK69_RS09930	COG3619	membrane
ETK69_RS09940	COG1404	Belongs to the peptidase S8 family
ETK69_RS09950	COG4195	phage-related replication protein
ETK69_RS09955	COG1764	response to oxidative stress
ETK69_RS09965	COG2076	Multidrug Resistance protein
ETK69_RS10005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETK69_RS10010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETK69_RS10015	COG4112	unkown
ETK69_RS10020	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS10030	COG0464	growth
ETK69_RS10035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETK69_RS10040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ETK69_RS10045	COG0789	Transcriptional regulator
ETK69_RS10050	COG0174	glutamine synthetase
ETK69_RS10080	COG2211	Major facilitator Superfamily
ETK69_RS10085	COG3507	Belongs to the glycosyl hydrolase 43 family
ETK69_RS10100	COG1070	Carbohydrate kinase
ETK69_RS10105	COG3848	Pyruvate phosphate dikinase
ETK69_RS10105	COG0574	Belongs to the PEP-utilizing enzyme family
ETK69_RS10130	COG2378	regulation of single-species biofilm formation
ETK69_RS10135	COG2318	DinB family
ETK69_RS10140	COG1064	alcohol dehydrogenase
ETK69_RS10170	COG0456	acetyltransferase
ETK69_RS10175	COG5444	nuclease activity
ETK69_RS10240	COG3397	chitin binding
ETK69_RS10260	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS10265	COG0756	dUTP diphosphatase activity
ETK69_RS10270	COG4195	phage-related replication protein
ETK69_RS10300	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETK69_RS10310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ETK69_RS10330	COG0785	Cytochrome C biogenesis protein
ETK69_RS10335	COG2201	protein-glutamate methylesterase activity
ETK69_RS10340	COG4846	Membrane protein involved in cytochrome C biogenesis
ETK69_RS10350	COG0071	Belongs to the small heat shock protein (HSP20) family
ETK69_RS10365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETK69_RS10370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS10390	COG0824	Thioesterase
ETK69_RS10400	COG4841	protein insertion into membrane
ETK69_RS10410	COG1832	CoA-binding protein
ETK69_RS10415	COG0187	DNA topoisomerase II activity
ETK69_RS10420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETK69_RS10430	COG1115	amino acid carrier protein
ETK69_RS10440	COG1063	alcohol dehydrogenase
ETK69_RS10445	COG0800	Aldolase
ETK69_RS10450	COG1312	Catalyzes the dehydration of D-mannonate
ETK69_RS10455	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS10460	COG1609	Transcriptional regulator
ETK69_RS10465	COG2271	Major facilitator Superfamily
ETK69_RS10510	COG2205	protein histidine kinase activity
ETK69_RS10515	COG0745	RESPONSE REGULATOR receiver
ETK69_RS10525	COG3507	Belongs to the glycosyl hydrolase 43 family
ETK69_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS10555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETK69_RS10560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETK69_RS10565	COG2610	gluconate transmembrane transporter activity
ETK69_RS10570	COG2124	cytochrome p450
ETK69_RS10590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETK69_RS10600	COG2246	polysaccharide biosynthetic process
ETK69_RS10605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETK69_RS10610	COG0586	Pfam SNARE associated Golgi protein
ETK69_RS10615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETK69_RS10620	COG1024	Enoyl-CoA hydratase
ETK69_RS10625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETK69_RS10630	COG0511	ligase activity, forming carbon-carbon bonds
ETK69_RS10635	COG0439	Biotin carboxylase
ETK69_RS10640	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS10645	COG1960	acyl-CoA dehydrogenase activity
ETK69_RS10650	COG1649	PFAM Uncharacterised BCR, COG1649
ETK69_RS10660	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ETK69_RS10660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS10675	COG2323	membrane
ETK69_RS10680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETK69_RS10690	COG2323	membrane
ETK69_RS10705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETK69_RS10750	COG2027	D-alanyl-D-alanine carboxypeptidase
ETK69_RS10755	COG2017	converts alpha-aldose to the beta-anomer
ETK69_RS10760	COG0534	Mate efflux family protein
ETK69_RS10775	COG0582	viral genome integration into host DNA
ETK69_RS10780	COG0166	Belongs to the GPI family
ETK69_RS10785	COG0405	Gamma-glutamyltransferase
ETK69_RS10795	COG0640	Transcriptional regulator
ETK69_RS10800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETK69_RS10810	COG0604	alcohol dehydrogenase
ETK69_RS10820	COG0493	'glutamate synthase
ETK69_RS10825	COG0067	glutamate synthase
ETK69_RS10825	COG0070	glutamate synthase
ETK69_RS10825	COG0069	glutamate synthase activity
ETK69_RS10830	COG0583	DNA-binding transcription factor activity
ETK69_RS10835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETK69_RS10850	COG0300	oxidoreductase activity
ETK69_RS10855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETK69_RS10865	COG2814	Major facilitator Superfamily
ETK69_RS10870	COG1070	Carbohydrate kinase
ETK69_RS10880	COG0243	molybdopterin cofactor binding
ETK69_RS10910	COG5444	nuclease activity
ETK69_RS10915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETK69_RS10920	COG0662	Cupin 2, conserved barrel domain protein
ETK69_RS10920	COG2207	Transcriptional regulator
ETK69_RS10925	COG1309	transcriptional regulator
ETK69_RS10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS10940	COG0640	Transcriptional regulator
ETK69_RS10945	COG0741	lytic transglycosylase activity
ETK69_RS10950	COG2322	membrane
ETK69_RS10965	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETK69_RS10975	COG3584	3D domain protein
ETK69_RS10975	COG1388	LysM domain
ETK69_RS10980	COG0514	ATP-dependent DNA helicase (RecQ)
ETK69_RS10990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETK69_RS10995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETK69_RS11010	COG0071	Belongs to the small heat shock protein (HSP20) family
ETK69_RS11040	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS11045	COG1657	PFAM Prenyltransferase squalene oxidase
ETK69_RS11050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETK69_RS11055	COG0733	neurotransmitter:sodium symporter activity
ETK69_RS11060	COG0385	Bile acid
ETK69_RS11065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS11070	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETK69_RS11080	COG4548	von Willebrand factor, type A
ETK69_RS11085	COG0714	Associated with various cellular activities
ETK69_RS11090	COG2032	superoxide dismutase activity
ETK69_RS11095	COG0791	NLP P60 protein
ETK69_RS11095	COG1388	LysM domain
ETK69_RS11100	COG1819	glycosyl
ETK69_RS11105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETK69_RS11110	COG0534	Mate efflux family protein
ETK69_RS11115	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS11120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETK69_RS11125	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETK69_RS11135	COG2962	Rard protein
ETK69_RS11150	COG1942	4-Oxalocrotonate Tautomerase
ETK69_RS11160	COG1733	regulation of RNA biosynthetic process
ETK69_RS11165	COG0778	Nitroreductase
ETK69_RS11170	COG0400	carboxylic ester hydrolase activity
ETK69_RS11175	COG0346	lactoylglutathione lyase activity
ETK69_RS11185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETK69_RS11195	COG2723	6-phospho-beta-galactosidase activity
ETK69_RS11200	COG2188	Transcriptional regulator
ETK69_RS11205	COG0793	Belongs to the peptidase S41A family
ETK69_RS11205	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS11210	COG2226	methyltransferase
ETK69_RS11220	COG1876	peptidase activity
ETK69_RS11240	COG0671	phosphoesterase, PA-phosphatase related
ETK69_RS11270	COG1509	lysine 2,3-aminomutase activity
ETK69_RS11275	COG0456	acetyltransferase
ETK69_RS11280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETK69_RS11285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETK69_RS11290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETK69_RS11295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETK69_RS11310	COG0456	acetyltransferase
ETK69_RS11315	COG0463	Glycosyl transferase, family 2
ETK69_RS11330	COG4641	Protein conserved in bacteria
ETK69_RS11340	COG1086	Polysaccharide biosynthesis protein
ETK69_RS11355	COG1846	Transcriptional regulator
ETK69_RS11360	COG4698	Protein conserved in bacteria
ETK69_RS11365	COG2755	lipolytic protein G-D-S-L family
ETK69_RS11370	COG1999	signal sequence binding
ETK69_RS11380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETK69_RS11385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETK69_RS11390	COG1272	protein, Hemolysin III
ETK69_RS11395	COG0204	Acyl-transferase
ETK69_RS11400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETK69_RS11415	COG2521	methyltransferase
ETK69_RS11415	COG2136	Putative SAM-dependent methyltransferase
ETK69_RS11430	COG1413	lyase activity
ETK69_RS11435	COG1418	mRNA catabolic process
ETK69_RS11440	COG0386	Belongs to the glutathione peroxidase family
ETK69_RS11450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETK69_RS11460	COG1278	Cold shock
ETK69_RS11480	COG0328	RNA-DNA hybrid ribonuclease activity
ETK69_RS11485	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ETK69_RS11490	COG0328	RNA-DNA hybrid ribonuclease activity
ETK69_RS11500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS11515	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETK69_RS11545	COG1335	isochorismatase
ETK69_RS11555	COG2233	PERMEase
ETK69_RS11565	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ETK69_RS11570	COG1199	ATP-dependent helicase activity
ETK69_RS11585	COG0116	Belongs to the methyltransferase superfamily
ETK69_RS11615	COG3359	exonuclease
ETK69_RS11620	COG1111	helicase
ETK69_RS11620	COG1205	dead DEAH box helicase
ETK69_RS11625	COG2190	(PTS) system
ETK69_RS11630	COG0071	Belongs to the small heat shock protein (HSP20) family
ETK69_RS11670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETK69_RS11670	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETK69_RS11680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETK69_RS11685	COG3935	DnaD domain protein
ETK69_RS11695	COG0436	Aminotransferase
ETK69_RS11700	COG5353	protein conserved in bacteria
ETK69_RS11710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETK69_RS11710	COG1199	ATP-dependent helicase activity
ETK69_RS11740	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS11745	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETK69_RS11760	COG1694	Mazg nucleotide pyrophosphohydrolase
ETK69_RS11765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS11770	COG2140	Oxalate decarboxylase
ETK69_RS11780	COG4347	Protein of unknown function (DUF1405)
ETK69_RS11785	COG2010	Cytochrome c
ETK69_RS11785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETK69_RS11790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETK69_RS11795	COG0723	plastoquinol--plastocyanin reductase activity
ETK69_RS11810	COG0457	Tetratricopeptide repeat
ETK69_RS11820	COG0287	Prephenate dehydrogenase
ETK69_RS11855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETK69_RS11860	COG4401	Chorismate mutase type I
ETK69_RS11875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETK69_RS11880	COG0105	UTP biosynthetic process
ETK69_RS11885	COG0142	geranyltranstransferase activity
ETK69_RS11895	COG0142	geranyltranstransferase activity
ETK69_RS11910	COG0776	regulation of translation
ETK69_RS11915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETK69_RS11955	COG0539	negative regulation of cytoplasmic translation
ETK69_RS11965	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ETK69_RS11970	COG2959	enzyme of heme biosynthesis
ETK69_RS11975	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS11975	COG3773	Cell wall hydrolase
ETK69_RS11980	COG2339	peptidase activity
ETK69_RS11985	COG0492	ferredoxin-NADP+ reductase activity
ETK69_RS11990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETK69_RS11995	COG4862	establishment of competence for transformation
ETK69_RS12000	COG1408	metallophosphoesterase
ETK69_RS12010	COG1388	LysM domain
ETK69_RS12015	COG1266	CAAX protease self-immunity
ETK69_RS12020	COG0514	ATP-dependent DNA helicase (RecQ)
ETK69_RS12025	COG4955	Helix-turn-helix domain
ETK69_RS12030	COG1141	Ferredoxin
ETK69_RS12035	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETK69_RS12040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETK69_RS12050	COG1595	DNA-templated transcription, initiation
ETK69_RS12055	COG5002	protein histidine kinase activity
ETK69_RS12060	COG0745	RESPONSE REGULATOR receiver
ETK69_RS12065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETK69_RS12070	COG1333	cytochrome c biogenesis protein
ETK69_RS12075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS12080	COG1187	pseudouridine synthase activity
ETK69_RS12085	COG0700	Nucleoside recognition
ETK69_RS12090	COG2715	membrane protein required for spore maturation
ETK69_RS12095	COG1686	Belongs to the peptidase S11 family
ETK69_RS12120	COG1547	Domain of unknown function (DUF309)
ETK69_RS12130	COG0456	acetyltransferase
ETK69_RS12145	COG0307	riboflavin synthase, alpha
ETK69_RS12150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETK69_RS12150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETK69_RS12160	COG0681	Belongs to the peptidase S26 family
ETK69_RS12170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETK69_RS12175	COG4086	secreted protein
ETK69_RS12180	COG0019	diaminopimelate decarboxylase activity
ETK69_RS12185	COG0697	spore germination
ETK69_RS12200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETK69_RS12220	COG1191	sigma factor activity
ETK69_RS12230	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS12235	COG1686	Belongs to the peptidase S11 family
ETK69_RS12240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETK69_RS12245	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETK69_RS12250	COG4974	Belongs to the 'phage' integrase family
ETK69_RS12260	COG0735	belongs to the Fur family
ETK69_RS12265	COG1300	Membrane
ETK69_RS12280	COG0281	malic enzyme
ETK69_RS12285	COG1757	Na H antiporter
ETK69_RS12290	COG1027	Aspartate ammonia-lyase
ETK69_RS12295	COG0252	asparaginase activity
ETK69_RS12300	COG1396	sequence-specific DNA binding
ETK69_RS12305	COG1379	DNA repair
ETK69_RS12310	COG0494	nUDIX hydrolase
ETK69_RS12320	COG0667	Aldo Keto reductase
ETK69_RS12330	COG1073	alpha beta
ETK69_RS12340	COG4918	Iron-sulphur cluster biosynthesis
ETK69_RS12345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETK69_RS12345	COG0456	acetyltransferase
ETK69_RS12350	COG2329	Antibiotic biosynthesis monooxygenase
ETK69_RS12355	COG0456	acetyltransferase
ETK69_RS12360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETK69_RS12375	COG0628	permease
ETK69_RS12385	COG0346	lactoylglutathione lyase activity
ETK69_RS12395	COG3048	D-serine ammonia-lyase activity
ETK69_RS12400	COG0300	oxidoreductase activity
ETK69_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS12410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETK69_RS12415	COG1024	Enoyl-CoA hydratase
ETK69_RS12420	COG3425	synthase
ETK69_RS12425	COG2124	cytochrome p450
ETK69_RS12430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12430	COG3321	synthase
ETK69_RS12430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETK69_RS12430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETK69_RS12435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS12435	COG3321	synthase
ETK69_RS12440	COG3321	synthase
ETK69_RS12440	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS12440	COG0300	oxidoreductase activity
ETK69_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12445	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS12445	COG3321	synthase
ETK69_RS12445	COG0300	oxidoreductase activity
ETK69_RS12445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12445	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12450	COG3321	synthase
ETK69_RS12450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETK69_RS12450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS12450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12455	COG0300	oxidoreductase activity
ETK69_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12455	COG3321	synthase
ETK69_RS12455	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS12460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETK69_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12460	COG3321	synthase
ETK69_RS12460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETK69_RS12460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS12465	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS12470	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS12485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETK69_RS12485	COG2070	2-Nitropropane dioxygenase
ETK69_RS12490	COG0250	Participates in transcription elongation, termination and antitermination
ETK69_RS12515	COG0596	Alpha beta hydrolase
ETK69_RS12530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETK69_RS12535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETK69_RS12550	COG0706	membrane insertase activity
ETK69_RS12555	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETK69_RS12560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETK69_RS12565	COG0346	lactoylglutathione lyase activity
ETK69_RS12570	COG1376	ErfK ybiS ycfS ynhG family protein
ETK69_RS12575	COG4129	membrane
ETK69_RS12580	COG1126	abc transporter atp-binding protein
ETK69_RS12585	COG0765	amino acid transport
ETK69_RS12590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS12600	COG1597	lipid kinase activity
ETK69_RS12605	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETK69_RS12610	COG0022	dehydrogenase e1 component
ETK69_RS12615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETK69_RS12620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETK69_RS12625	COG3426	butyrate kinase activity
ETK69_RS12630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETK69_RS12635	COG0280	phosphate acetyltransferase
ETK69_RS12640	COG3290	protein histidine kinase activity
ETK69_RS12640	COG3829	transcription factor binding
ETK69_RS12650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETK69_RS12655	COG2079	MmgE PrpD family protein
ETK69_RS12660	COG0372	Belongs to the citrate synthase family
ETK69_RS12665	COG1960	acyl-CoA dehydrogenase activity
ETK69_RS12670	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETK69_RS12675	COG0183	Belongs to the thiolase family
ETK69_RS12680	COG0584	glycerophosphoryl diester phosphodiesterase
ETK69_RS12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS12705	COG1902	pentaerythritol trinitrate reductase activity
ETK69_RS12720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETK69_RS12725	COG0745	RESPONSE REGULATOR receiver
ETK69_RS12730	COG0750	zinc metalloprotease
ETK69_RS12735	COG0497	DNA recombination
ETK69_RS12745	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETK69_RS12755	COG0142	geranyltranstransferase activity
ETK69_RS12765	COG1570	exodeoxyribonuclease VII activity
ETK69_RS12780	COG1302	Protein conserved in bacteria
ETK69_RS12785	COG0439	Biotin carboxylase
ETK69_RS12790	COG0511	ligase activity, forming carbon-carbon bonds
ETK69_RS12830	COG3854	ATPases associated with a variety of cellular activities
ETK69_RS12845	COG0006	proline dipeptidase activity
ETK69_RS12855	COG3872	metal-dependent enzyme
ETK69_RS12865	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETK69_RS12880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETK69_RS12900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETK69_RS12915	COG1396	sequence-specific DNA binding
ETK69_RS12925	COG0681	Belongs to the peptidase S26 family
ETK69_RS12950	COG4940	Competence protein ComGF
ETK69_RS12960	COG4970	Tfp pilus assembly protein FimT
ETK69_RS12965	COG4537	Required for transformation and DNA binding
ETK69_RS12970	COG1459	type II secretion system
ETK69_RS12975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETK69_RS12985	COG1253	flavin adenine dinucleotide binding
ETK69_RS12990	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS13000	COG1393	Belongs to the ArsC family
ETK69_RS13010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS13020	COG0011	TIGRFAM Protein of
ETK69_RS13030	COG2866	Carboxypeptidase
ETK69_RS13035	COG1940	carbohydrate kinase activity
ETK69_RS13040	COG4483	Protein conserved in bacteria
ETK69_RS13045	COG1757	Na H antiporter
ETK69_RS13055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETK69_RS13070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETK69_RS13075	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETK69_RS13080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETK69_RS13085	COG0581	inorganic phosphate transmembrane transporter activity
ETK69_RS13090	COG0573	inorganic phosphate transmembrane transporter activity
ETK69_RS13095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETK69_RS13100	COG0768	penicillin binding
ETK69_RS13105	COG0477	Major facilitator Superfamily
ETK69_RS13110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETK69_RS13115	COG2839	Protein conserved in bacteria
ETK69_RS13120	COG5521	maltodextrose utilization protein MalA
ETK69_RS13125	COG1388	LysM domain
ETK69_RS13135	COG4709	membrane
ETK69_RS13140	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ETK69_RS13145	COG0735	belongs to the Fur family
ETK69_RS13150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS13165	COG0513	Belongs to the DEAD box helicase family
ETK69_RS13180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETK69_RS13185	COG2384	SAM-dependent methyltransferase
ETK69_RS13190	COG2010	Cytochrome c
ETK69_RS13195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETK69_RS13200	COG0358	DNA primase activity
ETK69_RS13215	COG0517	IMP dehydrogenase activity
ETK69_RS13220	COG0751	glycine-tRNA ligase activity
ETK69_RS13240	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETK69_RS13245	COG0295	cytidine deaminase activity
ETK69_RS13250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETK69_RS13260	COG1480	7TM receptor with intracellular HD hydrolase
ETK69_RS13265	COG1702	phosphate starvation-inducible protein PhoH
ETK69_RS13270	COG0561	phosphatase activity
ETK69_RS13285	COG4864	UPF0365 protein
ETK69_RS13290	COG1030	water channel activity
ETK69_RS13295	COG1610	YqeY-like protein
ETK69_RS13305	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETK69_RS13310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETK69_RS13315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETK69_RS13345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETK69_RS13360	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS13375	COG1466	dna polymerase III delta subunit
ETK69_RS13390	COG2333	competence protein COMEC
ETK69_RS13390	COG0658	competence protein
ETK69_RS13395	COG2131	deaminase
ETK69_RS13400	COG1596	polysaccharide export
ETK69_RS13400	COG1555	photosystem II stabilization
ETK69_RS13405	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETK69_RS13410	COG2226	methyltransferase
ETK69_RS13415	COG0799	negative regulation of ribosome biogenesis
ETK69_RS13420	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETK69_RS13430	COG1534	Rna-binding protein
ETK69_RS13435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETK69_RS13440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETK69_RS13445	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETK69_RS13455	COG2755	lipolytic protein G-D-S-L family
ETK69_RS13465	COG0398	Pfam SNARE associated Golgi protein
ETK69_RS13500	COG5444	nuclease activity
ETK69_RS13505	COG4282	regulation of fungal-type cell wall biogenesis
ETK69_RS13520	COG2207	Transcriptional regulator
ETK69_RS13520	COG3708	Transcriptional regulator
ETK69_RS13525	COG0583	DNA-binding transcription factor activity
ETK69_RS13540	COG5002	protein histidine kinase activity
ETK69_RS13540	COG0642	Histidine kinase
ETK69_RS13545	COG0745	RESPONSE REGULATOR receiver
ETK69_RS13550	COG2311	Membrane
ETK69_RS13555	COG0454	-acetyltransferase
ETK69_RS13560	COG0563	adenylate kinase activity
ETK69_RS13570	COG2814	Major facilitator Superfamily
ETK69_RS13580	COG0456	acetyltransferase
ETK69_RS13585	COG2318	DinB family
ETK69_RS13595	COG0561	phosphatase activity
ETK69_RS13600	COG0561	phosphatase activity
ETK69_RS13610	COG1482	cell wall glycoprotein biosynthetic process
ETK69_RS13615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETK69_RS13615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETK69_RS13615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS13620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS13620	COG3711	transcriptional antiterminator
ETK69_RS13630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ETK69_RS13635	COG0583	DNA-binding transcription factor activity
ETK69_RS13640	COG2814	Major facilitator Superfamily
ETK69_RS13645	COG2124	cytochrome p450
ETK69_RS13645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETK69_RS13650	COG1309	transcriptional regulator
ETK69_RS13655	COG2226	methyltransferase
ETK69_RS13670	COG2116	formate transmembrane transporter activity
ETK69_RS13675	COG5609	conserved protein (DUF2294)
ETK69_RS13680	COG3383	formate dehydrogenase (NAD+) activity
ETK69_RS13685	COG2427	Protein of unknown function (DUF1641)
ETK69_RS13695	COG0626	cystathionine gamma-synthase activity
ETK69_RS13700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETK69_RS13725	COG0768	penicillin binding
ETK69_RS13760	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS13760	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS13765	COG4824	toxin secretion phage lysis holin
ETK69_RS13785	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS13790	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETK69_RS13800	COG5280	Phage tail tape measure protein TP901
ETK69_RS13800	COG3953	SLT domain
ETK69_RS13895	COG0582	viral genome integration into host DNA
ETK69_RS13900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ETK69_RS14020	COG0826	peptidase U32
ETK69_RS14025	COG0826	peptidase U32
ETK69_RS14030	COG4122	O-methyltransferase activity
ETK69_RS14035	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETK69_RS14060	COG0628	permease
ETK69_RS14065	COG1126	abc transporter atp-binding protein
ETK69_RS14070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS14075	COG0765	amino acid transport
ETK69_RS14080	COG0765	amino acid transport
ETK69_RS14095	COG3881	PFAM PRC-barrel domain
ETK69_RS14100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETK69_RS14105	COG0457	Tetratricopeptide repeat
ETK69_RS14115	COG1104	cysteine desulfurase activity
ETK69_RS14120	COG1959	2 iron, 2 sulfur cluster binding
ETK69_RS14125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETK69_RS14130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ETK69_RS14150	COG4991	sh3 domain protein
ETK69_RS14150	COG3103	Sh3 type 3 domain protein
ETK69_RS14150	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS14160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ETK69_RS14170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETK69_RS14170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETK69_RS14175	COG5416	Lipopolysaccharide assembly protein A domain
ETK69_RS14180	COG0490	domain, Protein
ETK69_RS14185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETK69_RS14185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETK69_RS14195	COG2244	polysaccharide biosynthetic process
ETK69_RS14200	COG2323	membrane
ETK69_RS14210	COG1862	Preprotein translocase
ETK69_RS14255	COG1388	LysM domain
ETK69_RS14265	COG0157	Belongs to the NadC ModD family
ETK69_RS14270	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETK69_RS14275	COG1104	cysteine desulfurase activity
ETK69_RS14280	COG1827	regulation of RNA biosynthetic process
ETK69_RS14285	COG0077	Prephenate dehydratase
ETK69_RS14300	COG3290	protein histidine kinase activity
ETK69_RS14305	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETK69_RS14310	COG2868	ribosomal protein
ETK69_RS14320	COG1994	Peptidase M50
ETK69_RS14325	COG0739	heme binding
ETK69_RS14330	COG2894	cell division
ETK69_RS14340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ETK69_RS14350	COG1077	Cell shape determining protein MreB Mrl
ETK69_RS14370	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS14370	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS14375	COG4824	toxin secretion phage lysis holin
ETK69_RS14395	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS14400	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETK69_RS14410	COG5412	phage tail tape measure protein
ETK69_RS14410	COG3953	SLT domain
ETK69_RS14510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS14510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS14550	COG1396	sequence-specific DNA binding
ETK69_RS14580	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETK69_RS14585	COG0285	dihydrofolate synthase activity
ETK69_RS14590	COG0525	valine-tRNA ligase activity
ETK69_RS14600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETK69_RS14605	COG1388	LysM domain
ETK69_RS14615	COG0113	porphobilinogen synthase activity
ETK69_RS14620	COG1587	Uroporphyrinogen-III synthase
ETK69_RS14630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETK69_RS14650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETK69_RS14655	COG0470	DNA polymerase III
ETK69_RS14655	COG1067	ATP-dependent peptidase activity
ETK69_RS14670	COG1477	protein flavinylation
ETK69_RS14670	COG0457	Tetratricopeptide repeat
ETK69_RS14685	COG0473	3-isopropylmalate dehydrogenase activity
ETK69_RS14700	COG0440	acetolactate synthase activity
ETK69_RS14705	COG0028	Belongs to the TPP enzyme family
ETK69_RS14735	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ETK69_RS14760	COG0622	Phosphoesterase
ETK69_RS14765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETK69_RS14775	COG5401	PFAM Sporulation and spore germination
ETK69_RS14790	COG2197	response regulator
ETK69_RS14795	COG0824	Thioesterase
ETK69_RS14800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETK69_RS14805	COG1053	succinate dehydrogenase
ETK69_RS14810	COG2009	succinate dehydrogenase
ETK69_RS14815	COG1719	4-vinyl reductase, 4VR
ETK69_RS14820	COG0527	aspartate kinase activity
ETK69_RS14835	COG3118	belongs to the thioredoxin family
ETK69_RS14840	COG3534	alpha-L-arabinofuranosidase
ETK69_RS14845	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ETK69_RS14850	COG2086	electron transfer activity
ETK69_RS14855	COG1024	Enoyl-CoA hydratase
ETK69_RS14860	COG1309	transcriptional regulator
ETK69_RS14865	COG0318	PFAM AMP-dependent synthetase and ligase
ETK69_RS14875	COG3766	membrane
ETK69_RS14885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETK69_RS14885	COG1796	DNA polymerase
ETK69_RS14905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETK69_RS14905	COG0072	phenylalanine-tRNA ligase activity
ETK69_RS14910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETK69_RS14915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETK69_RS14925	COG3835	regulator
ETK69_RS14930	COG0277	FAD linked oxidase domain protein
ETK69_RS14935	COG0247	lactate metabolic process
ETK69_RS14940	COG1966	Carbon starvation protein
ETK69_RS14945	COG3534	alpha-L-arabinofuranosidase
ETK69_RS14950	COG0395	ABC-type sugar transport system, permease component
ETK69_RS14955	COG1175	transmembrane transport
ETK69_RS14960	COG1653	transport
ETK69_RS14970	COG0647	UMP catabolic process
ETK69_RS14975	COG0235	Class ii aldolase
ETK69_RS14980	COG1069	ribulokinase activity
ETK69_RS14985	COG2160	L-arabinose isomerase activity
ETK69_RS14990	COG3507	Belongs to the glycosyl hydrolase 43 family
ETK69_RS14995	COG1363	Peptidase, m42
ETK69_RS15005	COG3326	Membrane
ETK69_RS15020	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETK69_RS15025	COG1346	cytolysis
ETK69_RS15030	COG1380	Effector of murein hydrolase LrgA
ETK69_RS15035	COG3279	Response regulator of the LytR AlgR family
ETK69_RS15040	COG3275	phosphorelay sensor kinase activity
ETK69_RS15045	COG1011	Hydrolase
ETK69_RS15060	COG0398	Pfam SNARE associated Golgi protein
ETK69_RS15065	COG1484	DNA-dependent DNA replication
ETK69_RS15070	COG3611	Membrane attachment protein
ETK69_RS15085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETK69_RS15090	COG1733	regulation of RNA biosynthetic process
ETK69_RS15095	COG2814	Major facilitator Superfamily
ETK69_RS15100	COG0656	L-ascorbic acid biosynthetic process
ETK69_RS15105	COG0237	dephospho-CoA kinase activity
ETK69_RS15110	COG1971	Probably functions as a manganese efflux pump
ETK69_RS15115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETK69_RS15120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS15120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETK69_RS15125	COG5002	protein histidine kinase activity
ETK69_RS15130	COG0745	RESPONSE REGULATOR receiver
ETK69_RS15140	COG0538	isocitrate dehydrogenase activity
ETK69_RS15145	COG0372	Belongs to the citrate synthase family
ETK69_RS15150	COG0457	Tetratricopeptide repeat
ETK69_RS15180	COG0628	permease
ETK69_RS15185	COG3030	protein affecting phage T7 exclusion by the F plasmid
ETK69_RS15190	COG0469	pyruvate kinase activity
ETK69_RS15210	COG0281	malic enzyme
ETK69_RS15215	COG0587	DNA-directed DNA polymerase activity
ETK69_RS15235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETK69_RS15245	COG4109	DRTGG domain
ETK69_RS15255	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS15270	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETK69_RS15280	COG0827	DNA restriction-modification system
ETK69_RS15285	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETK69_RS15290	COG3874	Sporulation protein YtfJ
ETK69_RS15300	COG1714	RDD family
ETK69_RS15305	COG0616	signal peptide processing
ETK69_RS15310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETK69_RS15315	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ETK69_RS15320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETK69_RS15335	COG1104	cysteine desulfurase activity
ETK69_RS15340	COG1114	Component of the transport system for branched-chain amino acids
ETK69_RS15350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETK69_RS15355	COG1309	transcriptional regulator
ETK69_RS15360	COG1956	GAF domain-containing protein
ETK69_RS15365	COG2203	Gaf domain
ETK69_RS15365	COG2199	diguanylate cyclase activity
ETK69_RS15380	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS15385	COG4282	regulation of fungal-type cell wall biogenesis
ETK69_RS15430	COG1017	nitric oxide dioxygenase activity
ETK69_RS15430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETK69_RS15445	COG0693	protein deglycase activity
ETK69_RS15460	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETK69_RS15465	COG1378	Sugar-specific transcriptional regulator TrmB
ETK69_RS15490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETK69_RS15495	COG0454	-acetyltransferase
ETK69_RS15500	COG0517	IMP dehydrogenase activity
ETK69_RS15505	COG0123	including yeast histone deacetylase and acetoin utilization protein
ETK69_RS15510	COG1360	Flagellar Motor Protein
ETK69_RS15515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETK69_RS15520	COG1609	Transcriptional regulator
ETK69_RS15525	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETK69_RS15525	COG1605	Chorismate mutase
ETK69_RS15530	COG3118	belongs to the thioredoxin family
ETK69_RS15535	COG4980	gas vesicle protein
ETK69_RS15540	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETK69_RS15550	COG1674	ftsk spoiiie
ETK69_RS15555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETK69_RS15565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS15585	COG1363	Peptidase, m42
ETK69_RS15590	COG5584	Small secreted protein
ETK69_RS15595	COG0281	malic enzyme
ETK69_RS15600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETK69_RS15615	COG0510	thiamine kinase activity
ETK69_RS15620	COG1597	lipid kinase activity
ETK69_RS15630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETK69_RS15635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETK69_RS15640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETK69_RS15645	COG2252	PERMEase
ETK69_RS15650	COG4473	ABC transporter
ETK69_RS15655	COG1131	(ABC) transporter
ETK69_RS15660	COG1349	DNA-binding transcription factor activity
ETK69_RS15665	COG1187	pseudouridine synthase activity
ETK69_RS15670	COG2244	polysaccharide biosynthetic process
ETK69_RS15675	COG2081	HI0933 family
ETK69_RS15680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ETK69_RS15695	COG1609	Transcriptional regulator
ETK69_RS15700	COG1653	transport
ETK69_RS15705	COG1175	transmembrane transport
ETK69_RS15710	COG0395	ABC-type sugar transport system, permease component
ETK69_RS15715	COG1486	melibiose metabolic process
ETK69_RS15725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETK69_RS15740	COG2202	Pas domain
ETK69_RS15740	COG1366	Belongs to the anti-sigma-factor antagonist family
ETK69_RS15745	COG2814	Major facilitator Superfamily
ETK69_RS15750	COG5522	Integral membrane protein (intg_mem_TP0381)
ETK69_RS15755	COG0577	efflux transmembrane transporter activity
ETK69_RS15760	COG1136	(ABC) transporter
ETK69_RS15765	COG2205	protein histidine kinase activity
ETK69_RS15770	COG0745	RESPONSE REGULATOR receiver
ETK69_RS15775	COG0577	efflux transmembrane transporter activity
ETK69_RS15780	COG1136	(ABC) transporter
ETK69_RS15800	COG1131	(ABC) transporter
ETK69_RS15805	COG1725	Transcriptional regulator
ETK69_RS15815	COG0640	Transcriptional regulator
ETK69_RS15820	COG0477	Major facilitator Superfamily
ETK69_RS15825	COG1242	4 iron, 4 sulfur cluster binding
ETK69_RS15830	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETK69_RS15840	COG0584	glycerophosphoryl diester phosphodiesterase
ETK69_RS15850	COG2267	carboxylic ester hydrolase activity
ETK69_RS15855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETK69_RS15860	COG1113	amino acid transport
ETK69_RS15865	COG0367	asparagine synthase
ETK69_RS15885	COG1506	peptidase
ETK69_RS15890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETK69_RS15895	COG1116	anion transmembrane transporter activity
ETK69_RS15900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETK69_RS15905	COG0494	nUDIX hydrolase
ETK69_RS15910	COG4824	toxin secretion phage lysis holin
ETK69_RS15915	COG0783	Belongs to the Dps family
ETK69_RS15940	COG0288	reversible hydration of carbon dioxide
ETK69_RS15950	COG1271	oxidase subunit
ETK69_RS15955	COG1294	oxidase, subunit
ETK69_RS15965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETK69_RS15970	COG1321	iron dependent repressor
ETK69_RS15970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETK69_RS15975	COG1121	(ABC) transporter
ETK69_RS15980	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETK69_RS15985	COG4948	Mandelate Racemase Muconate Lactonizing
ETK69_RS15995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ETK69_RS16000	COG0596	Alpha beta hydrolase
ETK69_RS16010	COG1169	isochorismate synthase
ETK69_RS16015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETK69_RS16020	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETK69_RS16145	COG3859	Proton-coupled thiamine transporter YuaJ
ETK69_RS16150	COG2268	Band 7 protein
ETK69_RS16155	COG1585	Membrane protein implicated in regulation of membrane protease activity
ETK69_RS16160	COG2318	DinB family
ETK69_RS16170	COG1454	alcohol dehydrogenase
ETK69_RS16175	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS16180	COG1510	regulation of RNA biosynthetic process
ETK69_RS16190	COG0569	domain protein
ETK69_RS16195	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETK69_RS16200	COG1017	nitric oxide dioxygenase activity
ETK69_RS16200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETK69_RS16220	COG0457	Tetratricopeptide repeat
ETK69_RS16255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ETK69_RS16270	COG0628	permease
ETK69_RS16275	COG0673	inositol 2-dehydrogenase activity
ETK69_RS16280	COG0693	protein deglycase activity
ETK69_RS16285	COG0840	transmembrane signaling receptor activity
ETK69_RS16295	COG0840	transmembrane signaling receptor activity
ETK69_RS16300	COG0840	transmembrane signaling receptor activity
ETK69_RS16315	COG2070	2-Nitropropane dioxygenase
ETK69_RS16320	COG0432	Pfam Uncharacterised protein family UPF0047
ETK69_RS16325	COG0366	Alpha amylase catalytic
ETK69_RS16330	COG1253	flavin adenine dinucleotide binding
ETK69_RS16335	COG2738	Putative neutral zinc metallopeptidase
ETK69_RS16350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETK69_RS16380	COG1335	isochorismatase
ETK69_RS16395	COG2155	Conserved Protein
ETK69_RS16405	COG1098	S1 RNA binding domain
ETK69_RS16410	COG0436	Aminotransferase
ETK69_RS16415	COG1522	sequence-specific DNA binding
ETK69_RS16420	COG2267	carboxylic ester hydrolase activity
ETK69_RS16430	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ETK69_RS16435	COG2205	protein histidine kinase activity
ETK69_RS16445	COG5018	Exonuclease
ETK69_RS16450	COG2814	Major facilitator Superfamily
ETK69_RS16455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETK69_RS16460	COG3011	Protein conserved in bacteria
ETK69_RS16470	COG3290	protein histidine kinase activity
ETK69_RS16475	COG4565	transcriptional regulatory protein
ETK69_RS16480	COG1744	ABC transporter substrate-binding protein PnrA-like
ETK69_RS16485	COG3845	ABC transporter
ETK69_RS16490	COG4603	Belongs to the binding-protein-dependent transport system permease family
ETK69_RS16495	COG1079	Belongs to the binding-protein-dependent transport system permease family
ETK69_RS16505	COG2111	Na H antiporter
ETK69_RS16505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETK69_RS16510	COG2111	Na H antiporter
ETK69_RS16515	COG1006	Multisubunit Na H antiporter MnhC subunit
ETK69_RS16520	COG0651	ATP synthesis coupled electron transport
ETK69_RS16525	COG1863	multisubunit Na H antiporter MnhE subunit
ETK69_RS16530	COG2212	antiporter activity
ETK69_RS16535	COG1320	monovalent cation:proton antiporter activity
ETK69_RS16540	COG2050	protein possibly involved in aromatic compounds catabolism
ETK69_RS16545	COG2197	response regulator
ETK69_RS16550	COG4585	Histidine kinase
ETK69_RS16560	COG0142	geranyltranstransferase activity
ETK69_RS16580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ETK69_RS16585	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETK69_RS16590	COG1335	isochorismatase
ETK69_RS16595	COG5506	Protein of unknown function (DUF1694)
ETK69_RS16610	COG0628	permease
ETK69_RS16620	COG1418	mRNA catabolic process
ETK69_RS16625	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS16635	COG1511	domain protein
ETK69_RS16640	COG0433	COG0433 Predicted ATPase
ETK69_RS16640	COG1674	ftsk spoiiie
ETK69_RS16645	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETK69_RS16650	COG5417	Belongs to the EsaB family
ETK69_RS16655	COG4842	Belongs to the WXG100 family
ETK69_RS16660	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETK69_RS16660	COG2508	Transcriptional regulator
ETK69_RS16665	COG0686	Belongs to the AlaDH PNT family
ETK69_RS16670	COG5634	Uncharacterized conserved protein (DUF2278)
ETK69_RS16675	COG3251	PFAM MbtH domain protein
ETK69_RS16680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETK69_RS16685	COG3433	isochorismatase activity
ETK69_RS16685	COG1535	isochorismatase
ETK69_RS16690	COG1021	2,3-dihydroxybenzoate-AMP ligase
ETK69_RS16695	COG1169	isochorismate synthase
ETK69_RS16700	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS16705	COG2819	hydrolase of the alpha beta superfamily
ETK69_RS16710	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETK69_RS16715	COG1268	BioY protein
ETK69_RS16720	COG2056	Na+-H+ antiporter family
ETK69_RS16730	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ETK69_RS16735	COG3584	3D domain protein
ETK69_RS16750	COG1252	NADH dehydrogenase
ETK69_RS16780	COG1131	(ABC) transporter
ETK69_RS16800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETK69_RS16805	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ETK69_RS16810	COG0316	Belongs to the HesB IscA family
ETK69_RS16820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETK69_RS16830	COG1252	NADH dehydrogenase
ETK69_RS16835	COG4837	Protein of unknown function (DUF1462)
ETK69_RS16840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETK69_RS16845	COG4946	Tricorn protease homolog
ETK69_RS16845	COG0823	Involved in the tonB-independent uptake of proteins
ETK69_RS16845	COG1506	peptidase
ETK69_RS16855	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETK69_RS16860	COG0460	homoserine dehydrogenase
ETK69_RS16865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETK69_RS16870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETK69_RS16875	COG0647	UMP catabolic process
ETK69_RS16880	COG2445	Protein of unknown function DUF86
ETK69_RS16885	COG4470	Protein conserved in bacteria
ETK69_RS16900	COG0739	heme binding
ETK69_RS16910	COG0737	Belongs to the 5'-nucleotidase family
ETK69_RS16915	COG0730	response to heat
ETK69_RS16920	COG1801	Protein of unknown function DUF72
ETK69_RS16935	COG2508	Transcriptional regulator
ETK69_RS16940	COG0457	Tetratricopeptide repeat
ETK69_RS16955	COG2814	Major facilitator Superfamily
ETK69_RS16960	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETK69_RS16965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETK69_RS16970	COG2356	endonuclease I
ETK69_RS16975	COG3842	ATPase activity
ETK69_RS16980	COG2188	Transcriptional regulator
ETK69_RS16985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETK69_RS16990	COG0395	ABC-type sugar transport system, permease component
ETK69_RS16995	COG1175	transmembrane transport
ETK69_RS17000	COG1653	transport
ETK69_RS17005	COG2222	sugar isomerase
ETK69_RS17010	COG0789	Transcriptional regulator
ETK69_RS17035	COG0322	excinuclease ABC activity
ETK69_RS17040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETK69_RS17045	COG2226	methyltransferase
ETK69_RS17060	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS17065	COG0719	Fe-S assembly protein
ETK69_RS17070	COG0822	iron-sulfur transferase activity
ETK69_RS17075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETK69_RS17080	COG0719	Fe-S assembly protein
ETK69_RS17085	COG0396	ATPase activity
ETK69_RS17095	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETK69_RS17100	COG1464	Belongs to the NlpA lipoprotein family
ETK69_RS17105	COG2011	ABC-type metal ion transport system permease component
ETK69_RS17110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETK69_RS17120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETK69_RS17125	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETK69_RS17140	COG1393	Belongs to the ArsC family
ETK69_RS17145	COG1960	acyl-CoA dehydrogenase activity
ETK69_RS17150	COG0183	Belongs to the thiolase family
ETK69_RS17155	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETK69_RS17155	COG1024	Enoyl-CoA hydratase
ETK69_RS17175	COG5577	PFAM Coat F domain
ETK69_RS17180	COG1846	Transcriptional regulator
ETK69_RS17185	COG0477	Major facilitator Superfamily
ETK69_RS17215	COG1120	ATPase activity
ETK69_RS17230	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS17235	COG0783	Belongs to the Dps family
ETK69_RS17240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETK69_RS17250	COG0745	RESPONSE REGULATOR receiver
ETK69_RS17255	COG2205	protein histidine kinase activity
ETK69_RS17255	COG2770	Histidine kinase
ETK69_RS17265	COG1309	transcriptional regulator
ETK69_RS17270	COG0114	fumarate hydratase activity
ETK69_RS17280	COG0697	spore germination
ETK69_RS17285	COG0814	amino acid
ETK69_RS17295	COG2197	response regulator
ETK69_RS17300	COG4585	Histidine kinase
ETK69_RS17305	COG4758	membrane
ETK69_RS17310	COG3595	metallopeptidase activity
ETK69_RS17315	COG1842	Phage shock protein A
ETK69_RS17320	COG4758	membrane
ETK69_RS17325	COG2814	Major facilitator Superfamily
ETK69_RS17330	COG2096	Adenosyltransferase
ETK69_RS17335	COG1120	ATPase activity
ETK69_RS17340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS17345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETK69_RS17350	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS17355	COG3386	PFAM SMP-30 Gluconolaconase
ETK69_RS17360	COG2205	protein histidine kinase activity
ETK69_RS17365	COG0745	RESPONSE REGULATOR receiver
ETK69_RS17375	COG1191	sigma factor activity
ETK69_RS17385	COG2140	Oxalate decarboxylase
ETK69_RS17395	COG1120	ATPase activity
ETK69_RS17400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS17405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS17410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETK69_RS17415	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ETK69_RS17420	COG0531	amino acid
ETK69_RS17435	COG1988	membrane-bound metal-dependent
ETK69_RS17445	COG1910	domain protein
ETK69_RS17450	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETK69_RS17455	COG4149	molybdate abc transporter
ETK69_RS17460	COG2197	response regulator
ETK69_RS17465	COG3850	Histidine kinase
ETK69_RS17470	COG1131	(ABC) transporter
ETK69_RS17480	COG0842	Transport permease protein
ETK69_RS17485	COG0656	L-ascorbic acid biosynthetic process
ETK69_RS17510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETK69_RS17515	COG3973	AAA domain
ETK69_RS17520	COG2860	membrane
ETK69_RS17530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ETK69_RS17535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ETK69_RS17540	COG2217	Heavy metal translocating P-type atpase
ETK69_RS17545	COG2217	Heavy metal translocating P-type atpase
ETK69_RS17550	COG2608	mercury ion transmembrane transporter activity
ETK69_RS17555	COG1937	Protein conserved in bacteria
ETK69_RS17560	COG0673	inositol 2-dehydrogenase activity
ETK69_RS17570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS17575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETK69_RS17580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS17585	COG1126	abc transporter atp-binding protein
ETK69_RS17590	COG0765	amino acid transport
ETK69_RS17595	COG0765	amino acid transport
ETK69_RS17600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS17605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETK69_RS17610	COG0454	-acetyltransferase
ETK69_RS17615	COG0583	DNA-binding transcription factor activity
ETK69_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS17625	COG2732	(Barnase) inhibitor
ETK69_RS17635	COG2732	(Barnase) inhibitor
ETK69_RS17655	COG4824	toxin secretion phage lysis holin
ETK69_RS17675	COG5434	Belongs to the glycosyl hydrolase 28 family
ETK69_RS17680	COG1388	LysM domain
ETK69_RS17680	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETK69_RS17755	COG4626	Terminase
ETK69_RS17755	COG1802	Transcriptional regulator
ETK69_RS17785	COG0582	viral genome integration into host DNA
ETK69_RS17790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ETK69_RS17915	COG0582	viral genome integration into host DNA
ETK69_RS17930	COG0557	exoribonuclease II activity
ETK69_RS17935	COG1647	Serine aminopeptidase, S33
ETK69_RS17940	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETK69_RS17945	COG1476	TRANSCRIPTIONal
ETK69_RS17950	COG1396	sequence-specific DNA binding
ETK69_RS17955	COG1396	sequence-specific DNA binding
ETK69_RS17960	COG1733	regulation of RNA biosynthetic process
ETK69_RS17985	COG1131	(ABC) transporter
ETK69_RS17990	COG1174	glycine betaine transport
ETK69_RS17995	COG1732	Glycine betaine
ETK69_RS18000	COG1174	glycine betaine transport
ETK69_RS18005	COG1125	glycine betaine transport
ETK69_RS18005	COG0517	IMP dehydrogenase activity
ETK69_RS18010	COG1510	regulation of RNA biosynthetic process
ETK69_RS18015	COG1174	glycine betaine transport
ETK69_RS18020	COG1732	Glycine betaine
ETK69_RS18025	COG1174	glycine betaine transport
ETK69_RS18030	COG0517	IMP dehydrogenase activity
ETK69_RS18030	COG1125	glycine betaine transport
ETK69_RS18035	COG1510	regulation of RNA biosynthetic process
ETK69_RS18040	COG2095	MarC family integral membrane protein
ETK69_RS18045	COG3064	Membrane
ETK69_RS18055	COG0456	acetyltransferase
ETK69_RS18075	COG0126	phosphoglycerate kinase activity
ETK69_RS18085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETK69_RS18090	COG2390	Transcriptional regulator
ETK69_RS18095	COG2814	Major facilitator Superfamily
ETK69_RS18100	COG1609	Transcriptional regulator
ETK69_RS18105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS18110	COG0583	DNA-binding transcription factor activity
ETK69_RS18115	COG0697	spore germination
ETK69_RS18125	COG1113	amino acid transport
ETK69_RS18130	COG1737	Transcriptional regulator
ETK69_RS18135	COG1070	Carbohydrate kinase
ETK69_RS18160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETK69_RS18165	COG2186	Transcriptional regulator
ETK69_RS18170	COG1620	l-lactate permease
ETK69_RS18175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ETK69_RS18185	COG5039	Polysaccharide pyruvyl transferase
ETK69_RS18190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETK69_RS18195	COG0110	maltose O-acetyltransferase activity
ETK69_RS18200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETK69_RS18205	COG2244	polysaccharide biosynthetic process
ETK69_RS18210	COG1216	Glycosyl transferase, family 2
ETK69_RS18215	COG5039	Polysaccharide pyruvyl transferase
ETK69_RS18220	COG1216	Glycosyl transferase, family 2
ETK69_RS18230	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS18235	COG1215	transferase activity, transferring glycosyl groups
ETK69_RS18240	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS18245	COG1086	Polysaccharide biosynthesis protein
ETK69_RS18250	COG0489	protein tyrosine kinase activity
ETK69_RS18255	COG3944	biosynthesis protein
ETK69_RS18260	COG1396	sequence-specific DNA binding
ETK69_RS18265	COG2272	Belongs to the type-B carboxylesterase lipase family
ETK69_RS18275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETK69_RS18280	COG2364	Membrane
ETK69_RS18285	COG0456	acetyltransferase
ETK69_RS18290	COG3479	Phenolic acid decarboxylase
ETK69_RS18330	COG2223	nitrite transmembrane transporter activity
ETK69_RS18335	COG1609	Transcriptional regulator
ETK69_RS18345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETK69_RS18350	COG0366	Alpha amylase catalytic
ETK69_RS18355	COG1554	hydrolase, family 65, central catalytic
ETK69_RS18360	COG5521	maltodextrose utilization protein MalA
ETK69_RS18365	COG3833	ABC-type maltose transport systems, permease component
ETK69_RS18370	COG1175	transmembrane transport
ETK69_RS18375	COG2182	Extracellular solute-binding protein
ETK69_RS18380	COG0366	Alpha amylase catalytic
ETK69_RS18385	COG1609	Transcriptional regulator
ETK69_RS18395	COG1694	Mazg nucleotide pyrophosphohydrolase
ETK69_RS18400	COG0659	secondary active sulfate transmembrane transporter activity
ETK69_RS18405	COG0288	reversible hydration of carbon dioxide
ETK69_RS18415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETK69_RS18420	COG4290	ribonuclease
ETK69_RS18425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ETK69_RS18430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS18440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ETK69_RS18450	COG1051	belongs to the nudix hydrolase family
ETK69_RS18455	COG0492	ferredoxin-NADP+ reductase activity
ETK69_RS18460	COG3883	PFAM NLP P60 protein
ETK69_RS18460	COG0791	NLP P60 protein
ETK69_RS18465	COG0457	Tetratricopeptide repeat
ETK69_RS18470	COG5002	protein histidine kinase activity
ETK69_RS18475	COG0745	RESPONSE REGULATOR receiver
ETK69_RS18480	COG1132	(ABC) transporter
ETK69_RS18485	COG0140	phosphoribosyl-ATP diphosphatase activity
ETK69_RS18485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ETK69_RS18510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETK69_RS18525	COG4990	cell redox homeostasis
ETK69_RS18530	COG0110	maltose O-acetyltransferase activity
ETK69_RS18550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETK69_RS18560	COG2188	Transcriptional regulator
ETK69_RS18565	COG1309	transcriptional regulator
ETK69_RS18570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ETK69_RS18575	COG1950	PFAM Membrane protein of
ETK69_RS18580	COG1983	PspC domain protein
ETK69_RS18585	COG3595	metallopeptidase activity
ETK69_RS18600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETK69_RS18610	COG4897	Protein conserved in bacteria
ETK69_RS18615	COG0574	Belongs to the PEP-utilizing enzyme family
ETK69_RS18615	COG3848	Pyruvate phosphate dikinase
ETK69_RS18620	COG1309	transcriptional regulator
ETK69_RS18625	COG2814	Major facilitator Superfamily
ETK69_RS18640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETK69_RS18650	COG0793	Belongs to the peptidase S41A family
ETK69_RS18650	COG3409	Peptidoglycan-binding domain 1 protein
ETK69_RS18655	COG3420	alginic acid biosynthetic process
ETK69_RS18660	COG2177	Part of the ABC transporter FtsEX involved in
ETK69_RS18665	COG2884	Cell division ATP-binding protein ftsE
ETK69_RS18670	COG2010	Cytochrome c
ETK69_RS18675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS18690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETK69_RS18705	COG1516	flagellar protein fliS
ETK69_RS18710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETK69_RS18715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETK69_RS18735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETK69_RS18740	COG4786	Flagellar basal body rod
ETK69_RS18740	COG1256	bacterial-type flagellum assembly
ETK69_RS18745	COG3418	PFAM FlgN family protein
ETK69_RS18750	COG2747	anti-sigma28 factor FlgM
ETK69_RS18760	COG1040	competence protein
ETK69_RS18770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETK69_RS18775	COG1307	EDD domain protein, DegV family
ETK69_RS18780	COG2197	response regulator
ETK69_RS18785	COG4585	Histidine kinase
ETK69_RS18790	COG1739	Uncharacterized protein family UPF0029
ETK69_RS18795	COG1316	TRANSCRIPTIONal
ETK69_RS18800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETK69_RS18805	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS18810	COG1215	transferase activity, transferring glycosyl groups
ETK69_RS18815	COG3206	protein involved in exopolysaccharide biosynthesis
ETK69_RS18820	COG3307	-O-antigen
ETK69_RS18825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETK69_RS18830	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS18830	COG0297	glycogen (starch) synthase activity
ETK69_RS18835	COG2244	polysaccharide biosynthetic process
ETK69_RS18845	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETK69_RS18845	COG2247	cell wall binding repeat
ETK69_RS18850	COG2385	sporulation resulting in formation of a cellular spore
ETK69_RS18850	COG2247	cell wall binding repeat
ETK69_RS18860	COG1316	TRANSCRIPTIONal
ETK69_RS18865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ETK69_RS18870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETK69_RS18875	COG1134	teichoic acid transport
ETK69_RS18880	COG1682	transport, permease protein
ETK69_RS18885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETK69_RS18890	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS18895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETK69_RS18900	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ETK69_RS18905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETK69_RS18910	COG4193	domain, Protein
ETK69_RS18915	COG1482	cell wall glycoprotein biosynthetic process
ETK69_RS18920	COG0697	spore germination
ETK69_RS18925	COG0814	amino acid
ETK69_RS18940	COG2814	Major facilitator Superfamily
ETK69_RS18945	COG1316	TRANSCRIPTIONal
ETK69_RS18950	COG0561	phosphatase activity
ETK69_RS18955	COG2433	Pfam Transposase IS66
ETK69_RS18960	COG0791	NLP P60 protein
ETK69_RS18970	COG2843	Capsule synthesis protein
ETK69_RS18980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETK69_RS18990	COG0697	spore germination
ETK69_RS18995	COG0814	amino acid
ETK69_RS19005	COG1609	Transcriptional regulator
ETK69_RS19010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETK69_RS19020	COG1129	ABC transporter
ETK69_RS19025	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETK69_RS19030	COG1879	ABC-type sugar transport system periplasmic component
ETK69_RS19035	COG3103	Sh3 type 3 domain protein
ETK69_RS19040	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETK69_RS19045	COG3527	Alpha-acetolactate decarboxylase
ETK69_RS19050	COG0028	Belongs to the TPP enzyme family
ETK69_RS19055	COG0583	DNA-binding transcription factor activity
ETK69_RS19060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETK69_RS19075	COG5337	Spore coat protein CotH
ETK69_RS19085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETK69_RS19095	COG0405	Gamma-glutamyltransferase
ETK69_RS19100	COG1522	sequence-specific DNA binding
ETK69_RS19105	COG2059	Chromate
ETK69_RS19110	COG2059	Chromate
ETK69_RS19120	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETK69_RS19125	COG0583	DNA-binding transcription factor activity
ETK69_RS19170	COG3878	Protein conserved in bacteria
ETK69_RS19175	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETK69_RS19180	COG4464	protein tyrosine phosphatase activity
ETK69_RS19185	COG0489	protein tyrosine kinase activity
ETK69_RS19190	COG3944	biosynthesis protein
ETK69_RS19205	COG4715	Zinc finger, swim domain protein
ETK69_RS19210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETK69_RS19215	COG0561	phosphatase activity
ETK69_RS19220	COG1349	DNA-binding transcription factor activity
ETK69_RS19225	COG0629	single-stranded DNA binding
ETK69_RS19250	COG0457	Tetratricopeptide repeat
ETK69_RS19255	COG4786	Flagellar basal body rod
ETK69_RS19260	COG4786	Flagellar basal body rod
ETK69_RS19265	COG1077	Cell shape determining protein MreB Mrl
ETK69_RS19270	COG1609	Transcriptional regulator
ETK69_RS19275	COG1846	Transcriptional regulator
ETK69_RS19280	COG2814	Major facilitator Superfamily
ETK69_RS19285	COG1953	Uracil, thiamine, allantoin
ETK69_RS19290	COG0477	Major facilitator Superfamily
ETK69_RS19295	COG1335	isochorismatase
ETK69_RS19300	COG0004	ammonium transporteR
ETK69_RS19305	COG0347	Belongs to the P(II) protein family
ETK69_RS19310	COG0772	Belongs to the SEDS family
ETK69_RS19315	COG0671	phosphoesterase, PA-phosphatase related
ETK69_RS19325	COG0739	heme binding
ETK69_RS19330	COG1247	-acetyltransferase
ETK69_RS19345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETK69_RS19355	COG0726	polysaccharide deacetylase
ETK69_RS19365	COG1959	2 iron, 2 sulfur cluster binding
ETK69_RS19380	COG0831	urea catabolic process
ETK69_RS19390	COG1994	Peptidase M50
ETK69_RS19395	COG0457	Tetratricopeptide repeat
ETK69_RS19405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETK69_RS19410	COG2304	oxidoreductase activity
ETK69_RS19415	COG2304	oxidoreductase activity
ETK69_RS19420	COG2385	sporulation resulting in formation of a cellular spore
ETK69_RS19425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETK69_RS19435	COG4836	Membrane
ETK69_RS19505	COG0698	ribose 5-phosphate isomerase
ETK69_RS19510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETK69_RS19520	COG0009	L-threonylcarbamoyladenylate synthase
ETK69_RS19525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETK69_RS19545	COG2890	protein-(glutamine-N5) methyltransferase activity
ETK69_RS19550	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETK69_RS19555	COG0346	lactoylglutathione lyase activity
ETK69_RS19560	COG0789	Transcriptional regulator
ETK69_RS19565	COG0679	Auxin Efflux Carrier
ETK69_RS19570	COG0281	malic enzyme
ETK69_RS19585	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETK69_RS19590	COG1494	fructose-1,6-bisphosphatase
ETK69_RS19595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETK69_RS19605	COG0191	fructose-bisphosphate aldolase activity
ETK69_RS19610	COG2204	response regulator
ETK69_RS19615	COG4821	SIS domain
ETK69_RS19630	COG2181	nitrate reductase activity
ETK69_RS19630	COG0247	lactate metabolic process
ETK69_RS19635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETK69_RS19650	COG1132	(ABC) transporter
ETK69_RS19655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETK69_RS19665	COG2181	nitrate reductase activity
ETK69_RS19670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ETK69_RS19675	COG1140	nitrate reductase beta subunit
ETK69_RS19680	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ETK69_RS19685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETK69_RS19695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETK69_RS19700	COG2223	nitrite transmembrane transporter activity
ETK69_RS19710	COG4506	Protein conserved in bacteria
ETK69_RS19715	COG0457	Tetratricopeptide repeat
ETK69_RS19725	COG0010	Belongs to the arginase family
ETK69_RS19730	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETK69_RS19735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETK69_RS19750	COG1994	Peptidase M50
ETK69_RS19755	COG1942	4-Oxalocrotonate Tautomerase
ETK69_RS19760	COG1846	Transcriptional regulator
ETK69_RS19770	COG0531	amino acid
ETK69_RS19775	COG3465	dGTPase activity
ETK69_RS19780	COG1078	dGTPase activity
ETK69_RS19795	COG1695	Transcriptional regulator
ETK69_RS19805	COG1131	(ABC) transporter
ETK69_RS19810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETK69_RS19840	COG0583	DNA-binding transcription factor activity
ETK69_RS19845	COG2855	membrane
ETK69_RS19850	COG0280	phosphate acetyltransferase
ETK69_RS19860	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS19865	COG0436	Aminotransferase
ETK69_RS19895	COG2814	Major facilitator Superfamily
ETK69_RS19900	COG2814	Major facilitator Superfamily
ETK69_RS19905	COG0833	amino acid
ETK69_RS19910	COG4187	Peptidase family M20/M25/M40
ETK69_RS19915	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS19920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETK69_RS19925	COG2205	protein histidine kinase activity
ETK69_RS19930	COG0745	RESPONSE REGULATOR receiver
ETK69_RS19945	COG1131	(ABC) transporter
ETK69_RS19950	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ETK69_RS19955	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETK69_RS19960	COG1088	dTDP-glucose 4,6-dehydratase activity
ETK69_RS19965	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETK69_RS19970	COG3980	spore coat polysaccharide biosynthesis protein
ETK69_RS19980	COG2089	acid synthase
ETK69_RS19985	COG0456	acetyltransferase
ETK69_RS19990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETK69_RS19995	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETK69_RS20000	COG0463	Glycosyl transferase, family 2
ETK69_RS20010	COG2363	Small membrane protein
ETK69_RS20015	COG2233	PERMEase
ETK69_RS20030	COG1216	Glycosyl transferase, family 2
ETK69_RS20045	COG1695	Transcriptional regulator
ETK69_RS20050	COG0351	phosphomethylpyrimidine kinase
ETK69_RS20060	COG1621	beta-fructofuranosidase activity
ETK69_RS20065	COG1263	PTS System
ETK69_RS20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETK69_RS20070	COG3711	transcriptional antiterminator
ETK69_RS20080	COG1404	Belongs to the peptidase S8 family
ETK69_RS20085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETK69_RS20090	COG0778	Nitroreductase
ETK69_RS20095	COG0772	Belongs to the SEDS family
ETK69_RS20100	COG0454	-acetyltransferase
ETK69_RS20120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETK69_RS20125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETK69_RS20130	COG2261	transglycosylase associated protein
ETK69_RS20135	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETK69_RS20140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ETK69_RS20145	COG2246	polysaccharide biosynthetic process
ETK69_RS20150	COG1309	transcriptional regulator
ETK69_RS20170	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETK69_RS20175	COG2837	iron assimilation
ETK69_RS20180	COG2822	iron ion transport
ETK69_RS20195	COG0583	DNA-binding transcription factor activity
ETK69_RS20205	COG1346	cytolysis
ETK69_RS20210	COG1131	(ABC) transporter
ETK69_RS20240	COG4895	conserved protein (DUF2196)
ETK69_RS20250	COG5504	Zn-dependent protease
ETK69_RS20255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETK69_RS20260	COG0346	lactoylglutathione lyase activity
ETK69_RS20265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS20270	COG1404	Belongs to the peptidase S8 family
ETK69_RS20275	COG1442	glycosyl transferase family 8
ETK69_RS20280	COG2357	RelA SpoT domain protein
ETK69_RS20285	COG1575	Belongs to the MenA family. Type 1 subfamily
ETK69_RS20310	COG1696	Membrane protein involved in D-alanine export
ETK69_RS20320	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETK69_RS20325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETK69_RS20330	COG1486	melibiose metabolic process
ETK69_RS20335	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETK69_RS20340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS20345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS20350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETK69_RS20350	COG3711	transcriptional antiterminator
ETK69_RS20365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS20370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETK69_RS20380	COG0640	Transcriptional regulator
ETK69_RS20385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETK69_RS20390	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS20395	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETK69_RS20400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETK69_RS20405	COG2723	6-phospho-beta-galactosidase activity
ETK69_RS20410	COG1940	carbohydrate kinase activity
ETK69_RS20415	COG1482	cell wall glycoprotein biosynthetic process
ETK69_RS20425	COG0753	catalase activity
ETK69_RS20430	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETK69_RS20435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETK69_RS20440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETK69_RS20445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ETK69_RS20450	COG4988	ABC transporter
ETK69_RS20455	COG1294	oxidase, subunit
ETK69_RS20460	COG1271	oxidase subunit
ETK69_RS20465	COG3493	citrate carrier protein
ETK69_RS20470	COG0726	polysaccharide deacetylase
ETK69_RS20475	COG3842	ATPase activity
ETK69_RS20480	COG2508	Transcriptional regulator
ETK69_RS20485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS20495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETK69_RS20505	COG4894	glucomannan catabolic process
ETK69_RS20510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETK69_RS20515	COG0500	methyltransferase
ETK69_RS20520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETK69_RS20535	COG0693	protein deglycase activity
ETK69_RS20535	COG0753	catalase activity
ETK69_RS20540	COG2851	Citrate transporter
ETK69_RS20545	COG2273	Hydrolase Family 16
ETK69_RS20555	COG2270	Major facilitator Superfamily
ETK69_RS20560	COG0513	Belongs to the DEAD box helicase family
ETK69_RS20650	COG3209	COG3209 Rhs family protein
ETK69_RS20660	COG0697	spore germination
ETK69_RS20665	COG0589	response to stress
ETK69_RS20675	COG0494	nUDIX hydrolase
ETK69_RS20680	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ETK69_RS20685	COG3507	Belongs to the glycosyl hydrolase 43 family
ETK69_RS20710	COG0010	Belongs to the arginase family
ETK69_RS20715	COG0833	amino acid
ETK69_RS20720	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETK69_RS20725	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETK69_RS20735	COG2390	Transcriptional regulator
ETK69_RS20765	COG1131	(ABC) transporter
ETK69_RS20775	COG0561	phosphatase activity
ETK69_RS20805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETK69_RS20810	COG5294	Protein conserved in bacteria
ETK69_RS20815	COG0577	efflux transmembrane transporter activity
ETK69_RS20820	COG1136	(ABC) transporter
ETK69_RS20825	COG2205	protein histidine kinase activity
ETK69_RS20830	COG0745	RESPONSE REGULATOR receiver
ETK69_RS20845	COG1082	Xylose isomerase domain protein TIM barrel
ETK69_RS20855	COG2814	Major facilitator Superfamily
ETK69_RS20885	COG1349	DNA-binding transcription factor activity
ETK69_RS20890	COG0667	Aldo Keto reductase
ETK69_RS20895	COG2814	Major facilitator Superfamily
ETK69_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
ETK69_RS20915	COG2197	response regulator
ETK69_RS20920	COG4585	Histidine kinase
ETK69_RS20925	COG3239	Fatty acid desaturase
ETK69_RS20930	COG1309	transcriptional regulator
ETK69_RS20935	COG1012	belongs to the aldehyde dehydrogenase family
ETK69_RS20950	COG0640	Transcriptional regulator
ETK69_RS20955	COG2814	Major facilitator Superfamily
ETK69_RS20960	COG1714	RDD family
ETK69_RS20970	COG0450	alkyl hydroperoxide reductase
ETK69_RS20975	COG3634	alkyl hydroperoxide reductase activity
ETK69_RS20980	COG3177	Filamentation induced by cAMP protein fic
ETK69_RS20985	COG1113	amino acid transport
ETK69_RS20995	COG2080	2 iron, 2 sulfur cluster binding
ETK69_RS21010	COG2068	MobA-Related Protein
ETK69_RS21035	COG1192	Involved in chromosome partitioning
ETK69_RS21070	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ETK69_RS21075	COG0667	Aldo Keto reductase
ETK69_RS21080	COG0456	acetyltransferase
ETK69_RS21085	COG0457	Tetratricopeptide repeat
ETK69_RS21090	COG0010	Belongs to the arginase family
ETK69_RS21095	COG0833	amino acid
ETK69_RS21100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETK69_RS21105	COG5658	integral membrane protein
ETK69_RS21110	COG0640	Transcriptional regulator
ETK69_RS21115	COG3829	transcription factor binding
ETK69_RS21125	COG0488	(ABC) transporter
ETK69_RS21140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETK69_RS21145	COG3850	Histidine kinase
ETK69_RS21145	COG5002	protein histidine kinase activity
ETK69_RS21150	COG0745	RESPONSE REGULATOR receiver
ETK69_RS21160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETK69_RS21165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETK69_RS21170	COG4853	Protein conserved in bacteria
ETK69_RS21175	COG4863	YycH protein
ETK69_RS21180	COG5002	protein histidine kinase activity
ETK69_RS21185	COG0745	RESPONSE REGULATOR receiver
ETK69_RS21220	COG0346	lactoylglutathione lyase activity
ETK69_RS21225	COG0305	Participates in initiation and elongation during chromosome replication
ETK69_RS21240	COG3093	addiction module antidote protein HigA
ETK69_RS21250	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETK69_RS21255	COG0297	glycogen (starch) synthase activity
ETK69_RS21265	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ETK69_RS21270	COG0438	transferase activity, transferring glycosyl groups
ETK69_RS21280	COG2112	serine threonine protein kinase
ETK69_RS21290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ETK69_RS21295	COG4241	membrane
ETK69_RS21305	COG5577	PFAM Coat F domain
ETK69_RS21310	COG1733	regulation of RNA biosynthetic process
ETK69_RS21320	COG0697	spore germination
ETK69_RS21325	COG1621	beta-fructofuranosidase activity
ETK69_RS21330	COG1621	beta-fructofuranosidase activity
ETK69_RS21340	COG2318	DinB family
ETK69_RS21345	COG2211	Major facilitator Superfamily
ETK69_RS21360	COG0778	Nitroreductase
ETK69_RS21365	COG1846	Transcriptional regulator
ETK69_RS21370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETK69_RS21375	COG1846	Transcriptional regulator
ETK69_RS21380	COG2153	protein acetylation
ETK69_RS21390	COG0546	phosphoglycolate phosphatase activity
ETK69_RS21420	COG1404	Belongs to the peptidase S8 family
ETK69_RS21430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETK69_RS21435	COG0697	spore germination
ETK69_RS21470	COG1131	(ABC) transporter
ETK69_RS21485	COG1331	Highly conserved protein containing a thioredoxin domain
ETK69_RS21490	COG1266	CAAX protease self-immunity
ETK69_RS21495	COG0477	Major facilitator Superfamily
ETK69_RS21495	COG2814	Major facilitator Superfamily
ETK69_RS21500	COG0346	lactoylglutathione lyase activity
ETK69_RS21505	COG1609	Transcriptional regulator
ETK69_RS21515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETK69_RS21520	COG2169	Transcriptional regulator
ETK69_RS21530	COG0629	single-stranded DNA binding
ETK69_RS21540	COG0012	GTP binding
ETK69_RS21545	COG0243	molybdopterin cofactor binding
ETK69_RS21550	COG4481	Protein conserved in bacteria
ETK69_RS21555	COG3949	Membrane
ETK69_RS21570	COG1475	DNA binding
ETK69_RS21575	COG1192	Involved in chromosome partitioning
ETK69_RS21600	COG1847	R3H domain protein
ETK69_RS21605	COG0706	membrane insertase activity