locus-tag	class	description
PF986_RS00015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PF986_RS00020	COG0789	Transcriptional regulator
PF986_RS00025	COG1664	Polymer-forming cytoskeletal
PF986_RS00030	COG1664	Polymer-forming cytoskeletal
PF986_RS00035	COG2766	serine protein kinase
PF986_RS00045	COG1846	Transcriptional regulator
PF986_RS00050	COG1566	PFAM secretion protein HlyD family protein
PF986_RS00055	COG2814	Major facilitator Superfamily
PF986_RS00060	COG0655	NAD(P)H dehydrogenase (quinone) activity
PF986_RS00075	COG1725	Transcriptional regulator
PF986_RS00080	COG1131	(ABC) transporter
PF986_RS00085	COG1131	(ABC) transporter
PF986_RS00090	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PF986_RS00095	COG1278	Cold shock
PF986_RS00100	COG1464	Belongs to the NlpA lipoprotein family
PF986_RS00105	COG3706	GGDEF domain
PF986_RS00110	COG1823	symporter activity
PF986_RS00130	COG5577	PFAM Coat F domain
PF986_RS00135	COG4085	toxin activity
PF986_RS00135	COG1525	nuclease
PF986_RS00135	COG0737	Belongs to the 5'-nucleotidase family
PF986_RS00140	COG3764	Sortase (surface protein transpeptidase)
PF986_RS00145	COG0564	pseudouridine synthase activity
PF986_RS00155	COG0517	IMP dehydrogenase activity
PF986_RS00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PF986_RS00165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PF986_RS00165	COG3153	acetyltransferase
PF986_RS00170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PF986_RS00175	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PF986_RS00180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PF986_RS00190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PF986_RS00195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PF986_RS00200	COG2203	Gaf domain
PF986_RS00200	COG4585	Histidine kinase
PF986_RS00205	COG2197	response regulator
PF986_RS00210	COG0431	NADPH-dependent FMN reductase
PF986_RS00225	COG1388	LysM domain
PF986_RS00225	COG0791	NLP P60 protein
PF986_RS00230	COG1959	2 iron, 2 sulfur cluster binding
PF986_RS00240	COG2719	SpoVR family
PF986_RS00245	COG1785	Belongs to the alkaline phosphatase family
PF986_RS00250	COG0791	NLP P60 protein
PF986_RS00250	COG1388	LysM domain
PF986_RS00255	COG0583	DNA-binding transcription factor activity
PF986_RS00260	COG0372	Belongs to the citrate synthase family
PF986_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS00270	COG0531	amino acid
PF986_RS00275	COG0733	neurotransmitter:sodium symporter activity
PF986_RS00290	COG1595	DNA-templated transcription, initiation
PF986_RS00295	COG0204	Acyl-transferase
PF986_RS00300	COG1253	flavin adenine dinucleotide binding
PF986_RS00305	COG0789	Transcriptional regulator
PF986_RS00310	COG0436	Aminotransferase
PF986_RS00315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PF986_RS00320	COG1253	flavin adenine dinucleotide binding
PF986_RS00325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PF986_RS00330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PF986_RS00335	COG0584	glycerophosphoryl diester phosphodiesterase
PF986_RS00345	COG0668	transmembrane transport
PF986_RS00350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PF986_RS00355	COG0726	polysaccharide deacetylase
PF986_RS00360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PF986_RS00365	COG3226	Transcriptional regulator
PF986_RS00375	COG0589	response to stress
PF986_RS00380	COG1132	(ABC) transporter
PF986_RS00385	COG1132	(ABC) transporter
PF986_RS00390	COG0702	epimerase
PF986_RS00410	COG0189	ligase activity
PF986_RS00415	COG0189	ligase activity
PF986_RS00430	COG4335	DNA alkylation repair
PF986_RS00435	COG0561	phosphatase activity
PF986_RS00440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PF986_RS00450	COG0475	glutathione-regulated potassium exporter activity
PF986_RS00455	COG0490	domain, Protein
PF986_RS00465	COG1024	Enoyl-CoA hydratase
PF986_RS00475	COG4152	abc transporter atp-binding protein
PF986_RS00480	COG1668	transmembrane transport
PF986_RS00485	COG0420	3'-5' exonuclease activity
PF986_RS00490	COG4717	serine-type aminopeptidase activity
PF986_RS00505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PF986_RS00540	COG4980	gas vesicle protein
PF986_RS00555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PF986_RS00560	COG0537	adenosine 5'-monophosphoramidase activity
PF986_RS00565	COG1131	(ABC) transporter
PF986_RS00570	COG4473	ABC transporter
PF986_RS00580	COG1473	amidohydrolase
PF986_RS00585	COG3069	C4-dicarboxylate transmembrane transporter activity
PF986_RS00590	COG2329	Antibiotic biosynthesis monooxygenase
PF986_RS00595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PF986_RS00605	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PF986_RS00610	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PF986_RS00615	COG1309	transcriptional regulator
PF986_RS00620	COG1511	domain protein
PF986_RS00625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PF986_RS00635	COG1363	Peptidase, m42
PF986_RS00640	COG1301	dicarboxylic acid transport
PF986_RS00650	COG1234	tRNA 3'-trailer cleavage
PF986_RS00655	COG0095	Lipoate-protein ligase
PF986_RS00660	COG0702	epimerase
PF986_RS00665	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS00675	COG0501	Belongs to the peptidase M48B family
PF986_RS00680	COG1404	Belongs to the peptidase S8 family
PF986_RS00690	COG0406	alpha-ribazole phosphatase activity
PF986_RS00695	COG0183	Belongs to the thiolase family
PF986_RS00700	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS00705	COG1268	BioY protein
PF986_RS00710	COG0840	transmembrane signaling receptor activity
PF986_RS00715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PF986_RS00715	COG0723	plastoquinol--plastocyanin reductase activity
PF986_RS00720	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS00730	COG4903	ComK protein
PF986_RS00740	COG5646	InterPro IPR014922
PF986_RS00765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF986_RS00780	COG0398	Pfam SNARE associated Golgi protein
PF986_RS00785	COG0681	Belongs to the peptidase S26 family
PF986_RS00790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF986_RS00795	COG1846	Transcriptional regulator
PF986_RS00800	COG3180	Ammonia monooxygenase
PF986_RS00805	COG2814	Major facilitator Superfamily
PF986_RS00815	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PF986_RS00820	COG2323	membrane
PF986_RS00835	COG0420	3'-5' exonuclease activity
PF986_RS00840	COG0419	ATPase involved in DNA repair
PF986_RS00845	COG1403	HNH endonuclease
PF986_RS00885	COG0179	Fumarylacetoacetate (FAA) hydrolase
PF986_RS00900	COG0367	asparagine synthase
PF986_RS00905	COG1562	ergosterol biosynthetic process
PF986_RS00910	COG0534	Mate efflux family protein
PF986_RS00915	COG2207	Transcriptional regulator
PF986_RS00915	COG1917	Cupin 2, conserved barrel domain protein
PF986_RS00920	COG1609	Transcriptional regulator
PF986_RS00925	COG0673	inositol 2-dehydrogenase activity
PF986_RS00930	COG2318	DinB family
PF986_RS00935	COG1279	arginine transmembrane transporter activity
PF986_RS00940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF986_RS00945	COG1357	PFAM Pentapeptide repeats (8 copies)
PF986_RS00950	COG2153	protein acetylation
PF986_RS00955	COG0646	methionine synthase
PF986_RS00955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PF986_RS00965	COG2996	Protein conserved in bacteria
PF986_RS00970	COG1744	ABC transporter substrate-binding protein PnrA-like
PF986_RS00975	COG0840	transmembrane signaling receptor activity
PF986_RS00980	COG2124	cytochrome p450
PF986_RS00990	COG1307	EDD domain protein, DegV family
PF986_RS00995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS01015	COG0561	phosphatase activity
PF986_RS01020	COG1073	alpha beta
PF986_RS01025	COG2151	metal-sulfur cluster biosynthetic enzyme
PF986_RS01035	COG0277	FAD linked oxidase domain protein
PF986_RS01040	COG2271	Major facilitator Superfamily
PF986_RS01050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PF986_RS01060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PF986_RS01065	COG0505	Belongs to the CarA family
PF986_RS01070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PF986_RS01075	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PF986_RS01090	COG2267	carboxylic ester hydrolase activity
PF986_RS01100	COG1744	ABC transporter substrate-binding protein PnrA-like
PF986_RS01115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PF986_RS01120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PF986_RS01125	COG5504	Zn-dependent protease
PF986_RS01130	COG0444	Belongs to the ABC transporter superfamily
PF986_RS01135	COG4608	Belongs to the ABC transporter superfamily
PF986_RS01145	COG0601	transmembrane transport
PF986_RS01150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PF986_RS01160	COG0180	Tryptophanyl-tRNA synthetase
PF986_RS01165	COG4166	transmembrane transport
PF986_RS01170	COG0601	transmembrane transport
PF986_RS01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PF986_RS01180	COG0444	Belongs to the ABC transporter superfamily
PF986_RS01185	COG4608	Belongs to the ABC transporter superfamily
PF986_RS01195	COG0456	acetyltransferase
PF986_RS01200	COG1393	Belongs to the ArsC family
PF986_RS01205	COG0861	Integral membrane protein TerC family
PF986_RS01210	COG4862	establishment of competence for transformation
PF986_RS01215	COG4469	Competence protein
PF986_RS01220	COG1164	Oligoendopeptidase f
PF986_RS01230	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PF986_RS01235	COG2346	COG2346, Truncated hemoglobins
PF986_RS01240	COG0741	lytic transglycosylase activity
PF986_RS01245	COG4116	CYTH
PF986_RS01255	COG2357	RelA SpoT domain protein
PF986_RS01260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PF986_RS01265	COG0564	pseudouridine synthase activity
PF986_RS01275	COG0569	domain protein
PF986_RS01275	COG0475	glutathione-regulated potassium exporter activity
PF986_RS01280	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PF986_RS01285	COG0352	thiamine-phosphate diphosphorylase activity
PF986_RS01290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PF986_RS01295	COG2104	thiamine diphosphate biosynthetic process
PF986_RS01305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PF986_RS01310	COG0351	phosphomethylpyrimidine kinase
PF986_RS01315	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PF986_RS01370	COG0210	DNA helicase
PF986_RS01390	COG1131	(ABC) transporter
PF986_RS01400	COG2153	protein acetylation
PF986_RS01410	COG2382	esterase
PF986_RS01415	COG0626	cystathionine gamma-synthase activity
PF986_RS01420	COG0626	cystathionine gamma-synthase activity
PF986_RS01465	COG2070	2-Nitropropane dioxygenase
PF986_RS01465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PF986_RS01470	COG3425	synthase
PF986_RS01500	COG3321	synthase
PF986_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS01500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS01500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS01500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS01505	COG0300	oxidoreductase activity
PF986_RS01505	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS01505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS01505	COG3321	synthase
PF986_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS01510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS01510	COG3321	synthase
PF986_RS01510	COG4221	oxidoreductase activity
PF986_RS01540	COG0250	Participates in transcription elongation, termination and antitermination
PF986_RS01575	COG0537	adenosine 5'-monophosphoramidase activity
PF986_RS01590	COG2367	Beta-lactamase
PF986_RS01595	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PF986_RS01600	COG0477	Major facilitator Superfamily
PF986_RS01605	COG1846	Transcriptional regulator
PF986_RS01615	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PF986_RS01620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PF986_RS01625	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PF986_RS01630	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS01630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS01635	COG1447	Phosphotransferase system cellobiose-specific component IIA
PF986_RS01645	COG1349	DNA-binding transcription factor activity
PF986_RS01665	COG1285	pathogenesis
PF986_RS01675	COG2205	protein histidine kinase activity
PF986_RS01685	COG3383	formate dehydrogenase (NAD+) activity
PF986_RS01690	COG2427	Protein of unknown function (DUF1641)
PF986_RS01695	COG2124	cytochrome p450
PF986_RS01700	COG1819	glycosyl
PF986_RS01710	COG1587	Uroporphyrinogen-III synthase
PF986_RS01715	COG0390	transport system, permease component
PF986_RS01720	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PF986_RS01725	COG0697	spore germination
PF986_RS01730	COG4297	protein containing double-stranded beta helix domain
PF986_RS01740	COG1252	NADH dehydrogenase
PF986_RS01755	COG1609	Transcriptional regulator
PF986_RS01760	COG0246	Mannitol dehydrogenase
PF986_RS01765	COG2721	sulfolactate sulfo-lyase activity
PF986_RS01770	COG0745	RESPONSE REGULATOR receiver
PF986_RS01775	COG2205	protein histidine kinase activity
PF986_RS01775	COG2770	Histidine kinase
PF986_RS01795	COG4585	Histidine kinase
PF986_RS01800	COG2197	response regulator
PF986_RS01835	COG0730	response to heat
PF986_RS01840	COG2318	DinB family
PF986_RS01845	COG0457	Tetratricopeptide repeat
PF986_RS01855	COG1388	LysM domain
PF986_RS01855	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS01855	COG5632	N-Acetylmuramoyl-L-alanine amidase
PF986_RS01865	COG4195	phage-related replication protein
PF986_RS01870	COG2856	Zn peptidase
PF986_RS01875	COG1396	sequence-specific DNA binding
PF986_RS01885	COG1522	sequence-specific DNA binding
PF986_RS01890	COG1484	DNA-dependent DNA replication
PF986_RS01910	COG1595	DNA-templated transcription, initiation
PF986_RS01950	COG5632	N-Acetylmuramoyl-L-alanine amidase
PF986_RS01950	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS01970	COG0306	phosphate transporter
PF986_RS01975	COG1392	Phosphate transport regulator
PF986_RS01980	COG0531	amino acid
PF986_RS01985	COG0346	lactoylglutathione lyase activity
PF986_RS01990	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PF986_RS01995	COG0463	Glycosyl transferase, family 2
PF986_RS02005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF986_RS02010	COG0477	Major facilitator Superfamily
PF986_RS02015	COG2362	D-Aminopeptidase
PF986_RS02020	COG0601	transmembrane transport
PF986_RS02025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PF986_RS02030	COG0444	Belongs to the ABC transporter superfamily
PF986_RS02035	COG4166	transmembrane transport
PF986_RS02040	COG1619	proteins homologs of microcin C7 resistance protein MccF
PF986_RS02045	COG4948	Mandelate Racemase Muconate Lactonizing
PF986_RS02050	COG0791	NLP P60 protein
PF986_RS02055	COG4608	Belongs to the ABC transporter superfamily
PF986_RS02060	COG2706	6-phosphogluconolactonase activity
PF986_RS02065	COG1834	amidinotransferase
PF986_RS02070	COG1607	acyl-coa hydrolase
PF986_RS02075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PF986_RS02080	COG2076	Multidrug Resistance protein
PF986_RS02085	COG2076	Multidrug Resistance protein
PF986_RS02090	COG0788	formyltetrahydrofolate deformylase activity
PF986_RS02095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PF986_RS02105	COG1764	response to oxidative stress
PF986_RS02110	COG1846	Transcriptional regulator
PF986_RS02115	COG1764	response to oxidative stress
PF986_RS02130	COG0457	Tetratricopeptide repeat
PF986_RS02130	COG0463	Glycosyl transferase, family 2
PF986_RS02140	COG2814	Major facilitator Superfamily
PF986_RS02145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PF986_RS02155	COG1404	Belongs to the peptidase S8 family
PF986_RS02160	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS02165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PF986_RS02170	COG1122	ATPase activity
PF986_RS02175	COG4721	ABC-type cobalt transport system, permease component
PF986_RS02180	COG3858	chitin binding
PF986_RS02180	COG1388	LysM domain
PF986_RS02190	COG2239	Acts as a magnesium transporter
PF986_RS02195	COG0789	Transcriptional regulator
PF986_RS02210	COG1846	Transcriptional regulator
PF986_RS02215	COG0726	polysaccharide deacetylase
PF986_RS02220	COG1793	dna ligase
PF986_RS02220	COG3285	dna ligase
PF986_RS02225	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PF986_RS02230	COG0586	Pfam SNARE associated Golgi protein
PF986_RS02240	COG1191	sigma factor activity
PF986_RS02265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PF986_RS02270	COG2323	membrane
PF986_RS02280	COG3594	Acyltransferase
PF986_RS02285	COG5002	protein histidine kinase activity
PF986_RS02290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PF986_RS02310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PF986_RS02315	COG0436	Aminotransferase
PF986_RS02345	COG3852	Histidine kinase
PF986_RS02350	COG1846	Transcriptional regulator
PF986_RS02355	COG1360	Flagellar Motor Protein
PF986_RS02360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PF986_RS02365	COG0542	response to heat
PF986_RS02370	COG3949	Membrane
PF986_RS02385	COG0720	synthase
PF986_RS02390	COG0602	queuosine metabolic process
PF986_RS02395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PF986_RS02405	COG4873	Protein conserved in bacteria
PF986_RS02415	COG3773	Cell wall hydrolase
PF986_RS02420	COG2244	polysaccharide biosynthetic process
PF986_RS02425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS02430	COG2217	Heavy metal translocating P-type atpase
PF986_RS02435	COG0006	proline dipeptidase activity
PF986_RS02445	COG1609	Transcriptional regulator
PF986_RS02450	COG3711	transcriptional antiterminator
PF986_RS02455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS02455	COG2190	(PTS) system
PF986_RS02455	COG1263	PTS System
PF986_RS02460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS02465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PF986_RS02475	COG1533	DNA photolyase activity
PF986_RS02480	COG0840	transmembrane signaling receptor activity
PF986_RS02485	COG2084	Dehydrogenase
PF986_RS02490	COG2340	Cysteine-rich secretory protein family
PF986_RS02495	COG0768	penicillin binding
PF986_RS02500	COG4191	Histidine kinase
PF986_RS02505	COG0436	Aminotransferase
PF986_RS02515	COG0835	chemotaxis
PF986_RS02515	COG0784	Response regulator, receiver
PF986_RS02525	COG2814	Major facilitator Superfamily
PF986_RS02530	COG1376	ErfK ybiS ycfS ynhG family protein
PF986_RS02535	COG1408	metallophosphoesterase
PF986_RS02540	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS02550	COG2200	EAL domain
PF986_RS02555	COG4703	Protein of unknown function (DUF1797)
PF986_RS02560	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
PF986_RS02570	COG0517	IMP dehydrogenase activity
PF986_RS02575	COG0583	DNA-binding transcription factor activity
PF986_RS02580	COG0716	FMN binding
PF986_RS02590	COG0716	FMN binding
PF986_RS02610	COG0668	transmembrane transport
PF986_RS02615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS02635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PF986_RS02640	COG0303	'Molybdopterin
PF986_RS02645	COG1763	Mo-molybdopterin cofactor biosynthetic process
PF986_RS02650	COG0314	molybdopterin synthase activity
PF986_RS02655	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PF986_RS02665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PF986_RS02670	COG1136	(ABC) transporter
PF986_RS02675	COG0577	efflux transmembrane transporter activity
PF986_RS02680	COG1349	DNA-binding transcription factor activity
PF986_RS02685	COG1105	Belongs to the carbohydrate kinase PfkB family
PF986_RS02690	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF986_RS02690	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF986_RS02690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS02695	COG0681	Belongs to the peptidase S26 family
PF986_RS02705	COG0488	(ABC) transporter
PF986_RS02710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PF986_RS02715	COG2309	aminopeptidase activity
PF986_RS02725	COG1077	Cell shape determining protein MreB Mrl
PF986_RS02730	COG2002	toxin-antitoxin pair type II binding
PF986_RS02735	COG3852	Histidine kinase
PF986_RS02740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
PF986_RS02740	COG2105	PFAM AIG2 family protein
PF986_RS02745	COG0569	domain protein
PF986_RS02755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PF986_RS02765	COG0561	phosphatase activity
PF986_RS02770	COG0242	peptide deformylase activity
PF986_RS02780	COG0497	DNA recombination
PF986_RS02790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS02790	COG4221	oxidoreductase activity
PF986_RS02790	COG3321	synthase
PF986_RS02795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS02795	COG4221	oxidoreductase activity
PF986_RS02795	COG0300	oxidoreductase activity
PF986_RS02795	COG3321	synthase
PF986_RS02800	COG4221	oxidoreductase activity
PF986_RS02800	COG3321	synthase
PF986_RS02800	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS02805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS02805	COG3321	synthase
PF986_RS02805	COG4221	oxidoreductase activity
PF986_RS02805	COG0300	oxidoreductase activity
PF986_RS02810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS02810	COG3321	synthase
PF986_RS02810	COG0300	oxidoreductase activity
PF986_RS02810	COG4221	oxidoreductase activity
PF986_RS02815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS02815	COG0300	oxidoreductase activity
PF986_RS02815	COG3321	synthase
PF986_RS02815	COG4221	oxidoreductase activity
PF986_RS02820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS02820	COG4221	oxidoreductase activity
PF986_RS02820	COG3321	synthase
PF986_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS02825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF986_RS02830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PF986_RS02835	COG0022	dehydrogenase e1 component
PF986_RS02840	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF986_RS02845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF986_RS02850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS02865	COG1982	Orn Lys Arg decarboxylase major
PF986_RS02885	COG0483	inositol monophosphate 1-phosphatase activity
PF986_RS02895	COG3227	Zinc metalloprotease (Elastase)
PF986_RS02900	COG1595	DNA-templated transcription, initiation
PF986_RS02920	COG1217	gtp-binding protein TYPA
PF986_RS02930	COG4896	Protein conserved in bacteria
PF986_RS02940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PF986_RS02945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PF986_RS02950	COG2066	Belongs to the glutaminase family
PF986_RS02960	COG0772	Belongs to the SEDS family
PF986_RS02965	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PF986_RS02980	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PF986_RS02980	COG2010	Cytochrome c
PF986_RS02985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PF986_RS02990	COG1845	cytochrome c oxidase, subunit III
PF986_RS02995	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
PF986_RS03000	COG3336	cytochrome c oxidase
PF986_RS03010	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PF986_RS03015	COG2340	Cysteine-rich secretory protein family
PF986_RS03030	COG3679	Belongs to the UPF0342 family
PF986_RS03040	COG0742	ribosomal rna small subunit methyltransferase
PF986_RS03050	COG3314	Sporulation integral membrane protein YlbJ
PF986_RS03055	COG1752	Esterase of the alpha-beta hydrolase superfamily
PF986_RS03060	COG3480	Lon protease (S16) C-terminal proteolytic domain
PF986_RS03070	COG1399	metal-binding, possibly nucleic acid-binding protein
PF986_RS03090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PF986_RS03110	COG4839	cell division protein FtsL
PF986_RS03115	COG0768	penicillin binding
PF986_RS03120	COG0768	penicillin binding
PF986_RS03140	COG0772	Belongs to the SEDS family
PF986_RS03155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PF986_RS03160	COG0849	cell division
PF986_RS03165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PF986_RS03180	COG1191	sigma factor activity
PF986_RS03185	COG1191	sigma factor activity
PF986_RS03190	COG1119	ATPase activity
PF986_RS03195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PF986_RS03200	COG1873	PFAM PRC-barrel domain
PF986_RS03205	COG1496	oxidoreductase activity
PF986_RS03210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PF986_RS03220	COG0762	integral membrane protein
PF986_RS03225	COG2302	S4 RNA-binding domain
PF986_RS03230	COG3599	regulation of cell shape
PF986_RS03235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PF986_RS03240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PF986_RS03250	COG0564	pseudouridine synthase activity
PF986_RS03260	COG2233	PERMEase
PF986_RS03270	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PF986_RS03275	COG0505	Belongs to the CarA family
PF986_RS03280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PF986_RS03295	COG0284	orotidine-5'-phosphate decarboxylase activity
PF986_RS03300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PF986_RS03310	COG0306	phosphate transporter
PF986_RS03325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PF986_RS03330	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
PF986_RS03335	COG1648	precorrin-2 dehydrogenase activity
PF986_RS03350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PF986_RS03355	COG1561	YicC-like family, N-terminal region
PF986_RS03365	COG0194	GDP metabolic process
PF986_RS03375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PF986_RS03380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PF986_RS03385	COG0242	peptide deformylase activity
PF986_RS03395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PF986_RS03395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PF986_RS03405	COG0631	protein serine/threonine phosphatase activity
PF986_RS03410	COG0515	serine threonine protein kinase
PF986_RS03410	COG2815	serine threonine protein kinase
PF986_RS03420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PF986_RS03425	COG1564	THIamine pyrophosphokinase
PF986_RS03440	COG1302	Protein conserved in bacteria
PF986_RS03445	COG1461	Dihydroxyacetone kinase
PF986_RS03450	COG1760	l-serine dehydratase
PF986_RS03455	COG1760	l-serine dehydratase
PF986_RS03460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PF986_RS03475	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PF986_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS03495	COG1196	nuclear chromosome segregation
PF986_RS03500	COG0552	protein localization to endoplasmic reticulum
PF986_RS03515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PF986_RS03525	COG1837	Belongs to the UPF0109 family
PF986_RS03550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PF986_RS03565	COG2257	FlhB HrpN YscU SpaS Family
PF986_RS03575	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PF986_RS03580	COG0758	DNA mediated transformation
PF986_RS03585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PF986_RS03595	COG4974	Belongs to the 'phage' integrase family
PF986_RS03615	COG1815	bacterial-type flagellum-dependent cell motility
PF986_RS03620	COG1558	bacterial-type flagellum-dependent cell motility
PF986_RS03625	COG1677	Flagellar hook-basal body complex protein FliE
PF986_RS03630	COG1766	The M ring may be actively involved in energy transduction
PF986_RS03635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PF986_RS03640	COG1317	bacterial-type flagellum organization
PF986_RS03645	COG1157	protein secretion by the type III secretion system
PF986_RS03650	COG2882	bacterial-type flagellum organization
PF986_RS03655	COG3334	PFAM MgtE intracellular
PF986_RS03660	COG3144	bacterial-type flagellum assembly
PF986_RS03665	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PF986_RS03670	COG4786	Flagellar basal body rod
PF986_RS03675	COG1582	Flagellar protein (FlbD)
PF986_RS03680	COG1580	Controls the rotational direction of flagella during chemotaxis
PF986_RS03685	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PF986_RS03690	COG1776	CheC inhibitor of MCP methylation
PF986_RS03690	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PF986_RS03695	COG2201	protein-glutamate methylesterase activity
PF986_RS03700	COG3190	flagellar
PF986_RS03705	COG1338	Plays a role in the flagellum-specific transport system
PF986_RS03710	COG1987	bacterial-type flagellum assembly
PF986_RS03715	COG1684	flagellar biosynthetic protein fliR
PF986_RS03720	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PF986_RS03725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PF986_RS03730	COG1419	protein localization to endoplasmic reticulum
PF986_RS03735	COG0455	bacterial-type flagellum organization
PF986_RS03740	COG2201	protein-glutamate methylesterase activity
PF986_RS03745	COG0643	Histidine kinase
PF986_RS03745	COG2198	Histidine kinase
PF986_RS03750	COG0835	chemotaxis
PF986_RS03755	COG1776	CheC inhibitor of MCP methylation
PF986_RS03765	COG1191	sigma factor activity
PF986_RS03795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PF986_RS03800	COG4589	Belongs to the CDS family
PF986_RS03810	COG0750	zinc metalloprotease
PF986_RS03830	COG0195	Participates in both transcription termination and antitermination
PF986_RS03835	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PF986_RS03840	COG1358	cellular component organization or biogenesis
PF986_RS03850	COG1550	Protein conserved in bacteria
PF986_RS03865	COG0196	riboflavin kinase activity
PF986_RS03880	COG0726	polysaccharide deacetylase
PF986_RS03885	COG0612	Peptidase, M16
PF986_RS03890	COG1873	PFAM PRC-barrel domain
PF986_RS03895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PF986_RS03900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PF986_RS03905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PF986_RS03910	COG0527	aspartate kinase activity
PF986_RS03920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PF986_RS03925	COG0740	serine-type endopeptidase activity
PF986_RS03935	COG1674	ftsk spoiiie
PF986_RS03935	COG4980	gas vesicle protein
PF986_RS03940	COG2188	Transcriptional regulator
PF986_RS03945	COG2814	Major facilitator Superfamily
PF986_RS03950	COG1846	Transcriptional regulator
PF986_RS03955	COG1033	growth of symbiont in host cell
PF986_RS03955	COG2409	Drug exporters of the RND superfamily
PF986_RS03960	COG0612	Peptidase, M16
PF986_RS03965	COG0612	Peptidase, M16
PF986_RS03970	COG0300	oxidoreductase activity
PF986_RS03985	COG1426	Protein conserved in bacteria
PF986_RS03990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PF986_RS04005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF986_RS04015	COG1692	metallophosphoesterase
PF986_RS04020	COG2359	stage V sporulation protein S
PF986_RS04040	COG4550	Control of competence regulator ComK, YlbF/YmcA
PF986_RS04085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS04090	COG3425	synthase
PF986_RS04095	COG1024	Enoyl-CoA hydratase
PF986_RS04100	COG1024	Enoyl-CoA hydratase
PF986_RS04110	COG3321	synthase
PF986_RS04110	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS04110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS04110	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS04110	COG0300	oxidoreductase activity
PF986_RS04120	COG2124	cytochrome p450
PF986_RS04125	COG3209	COG3209 Rhs family protein
PF986_RS04130	COG3619	membrane
PF986_RS04140	COG1404	Belongs to the peptidase S8 family
PF986_RS04150	COG4195	phage-related replication protein
PF986_RS04155	COG1764	response to oxidative stress
PF986_RS04165	COG2076	Multidrug Resistance protein
PF986_RS04205	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PF986_RS04210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PF986_RS04215	COG4112	unkown
PF986_RS04220	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS04225	COG0464	growth
PF986_RS04230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PF986_RS04235	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PF986_RS04240	COG0789	Transcriptional regulator
PF986_RS04245	COG0174	glutamine synthetase
PF986_RS04265	COG2211	Major facilitator Superfamily
PF986_RS04270	COG3507	Belongs to the glycosyl hydrolase 43 family
PF986_RS04285	COG1070	Carbohydrate kinase
PF986_RS04290	COG0574	Belongs to the PEP-utilizing enzyme family
PF986_RS04290	COG3848	Pyruvate phosphate dikinase
PF986_RS04315	COG2378	regulation of single-species biofilm formation
PF986_RS04320	COG2318	DinB family
PF986_RS04325	COG1064	alcohol dehydrogenase
PF986_RS04355	COG5444	nuclease activity
PF986_RS04415	COG3397	chitin binding
PF986_RS04440	COG5434	Belongs to the glycosyl hydrolase 28 family
PF986_RS04445	COG0756	dUTP diphosphatase activity
PF986_RS04450	COG4195	phage-related replication protein
PF986_RS04485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PF986_RS04495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PF986_RS04515	COG0785	Cytochrome C biogenesis protein
PF986_RS04520	COG2201	protein-glutamate methylesterase activity
PF986_RS04525	COG4846	Membrane protein involved in cytochrome C biogenesis
PF986_RS04535	COG0071	Belongs to the small heat shock protein (HSP20) family
PF986_RS04550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PF986_RS04555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS04575	COG0824	Thioesterase
PF986_RS04585	COG4841	protein insertion into membrane
PF986_RS04595	COG1832	CoA-binding protein
PF986_RS04600	COG0187	DNA topoisomerase II activity
PF986_RS04605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PF986_RS04620	COG1115	amino acid carrier protein
PF986_RS04630	COG1063	alcohol dehydrogenase
PF986_RS04635	COG0800	Aldolase
PF986_RS04640	COG1312	Catalyzes the dehydration of D-mannonate
PF986_RS04645	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS04650	COG1609	Transcriptional regulator
PF986_RS04655	COG2271	Major facilitator Superfamily
PF986_RS04700	COG2205	protein histidine kinase activity
PF986_RS04705	COG0745	RESPONSE REGULATOR receiver
PF986_RS04715	COG3507	Belongs to the glycosyl hydrolase 43 family
PF986_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS04745	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PF986_RS04750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PF986_RS04755	COG2610	gluconate transmembrane transporter activity
PF986_RS04760	COG2124	cytochrome p450
PF986_RS04780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PF986_RS04790	COG2246	polysaccharide biosynthetic process
PF986_RS04795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PF986_RS04800	COG0586	Pfam SNARE associated Golgi protein
PF986_RS04805	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PF986_RS04810	COG1024	Enoyl-CoA hydratase
PF986_RS04815	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PF986_RS04820	COG0511	ligase activity, forming carbon-carbon bonds
PF986_RS04825	COG0439	Biotin carboxylase
PF986_RS04830	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS04835	COG1960	acyl-CoA dehydrogenase activity
PF986_RS04840	COG1649	PFAM Uncharacterised BCR, COG1649
PF986_RS04850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS04850	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
PF986_RS04865	COG2323	membrane
PF986_RS04870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PF986_RS04880	COG2323	membrane
PF986_RS04895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PF986_RS04940	COG2027	D-alanyl-D-alanine carboxypeptidase
PF986_RS04945	COG2017	converts alpha-aldose to the beta-anomer
PF986_RS04950	COG0534	Mate efflux family protein
PF986_RS04965	COG0582	viral genome integration into host DNA
PF986_RS04970	COG0166	Belongs to the GPI family
PF986_RS04975	COG0405	Gamma-glutamyltransferase
PF986_RS04980	COG2814	Major facilitator Superfamily
PF986_RS04985	COG0640	Transcriptional regulator
PF986_RS04990	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PF986_RS05000	COG0604	alcohol dehydrogenase
PF986_RS05010	COG0493	'glutamate synthase
PF986_RS05015	COG0070	glutamate synthase
PF986_RS05015	COG0067	glutamate synthase
PF986_RS05015	COG0069	glutamate synthase activity
PF986_RS05020	COG0583	DNA-binding transcription factor activity
PF986_RS05025	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PF986_RS05040	COG0300	oxidoreductase activity
PF986_RS05045	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PF986_RS05055	COG2814	Major facilitator Superfamily
PF986_RS05060	COG1070	Carbohydrate kinase
PF986_RS05065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PF986_RS05070	COG0243	molybdopterin cofactor binding
PF986_RS05100	COG5444	nuclease activity
PF986_RS05105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF986_RS05110	COG0662	Cupin 2, conserved barrel domain protein
PF986_RS05110	COG2207	Transcriptional regulator
PF986_RS05115	COG1309	transcriptional regulator
PF986_RS05120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS05130	COG0640	Transcriptional regulator
PF986_RS05135	COG0741	lytic transglycosylase activity
PF986_RS05140	COG2322	membrane
PF986_RS05155	COG1619	proteins homologs of microcin C7 resistance protein MccF
PF986_RS05165	COG1388	LysM domain
PF986_RS05165	COG3584	3D domain protein
PF986_RS05170	COG0514	ATP-dependent DNA helicase (RecQ)
PF986_RS05180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PF986_RS05185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PF986_RS05200	COG0071	Belongs to the small heat shock protein (HSP20) family
PF986_RS05230	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS05240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PF986_RS05245	COG0733	neurotransmitter:sodium symporter activity
PF986_RS05250	COG0385	Bile acid
PF986_RS05255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS05260	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF986_RS05270	COG4548	von Willebrand factor, type A
PF986_RS05275	COG0714	Associated with various cellular activities
PF986_RS05280	COG2032	superoxide dismutase activity
PF986_RS05285	COG0791	NLP P60 protein
PF986_RS05285	COG1388	LysM domain
PF986_RS05290	COG1819	glycosyl
PF986_RS05295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PF986_RS05300	COG0534	Mate efflux family protein
PF986_RS05305	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS05310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PF986_RS05315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PF986_RS05325	COG2962	Rard protein
PF986_RS05340	COG1942	4-Oxalocrotonate Tautomerase
PF986_RS05350	COG1733	regulation of RNA biosynthetic process
PF986_RS05355	COG0778	Nitroreductase
PF986_RS05360	COG0400	carboxylic ester hydrolase activity
PF986_RS05365	COG0346	lactoylglutathione lyase activity
PF986_RS05375	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF986_RS05385	COG2723	6-phospho-beta-galactosidase activity
PF986_RS05390	COG2188	Transcriptional regulator
PF986_RS05395	COG0793	Belongs to the peptidase S41A family
PF986_RS05395	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS05400	COG2226	methyltransferase
PF986_RS05410	COG1876	peptidase activity
PF986_RS05430	COG0671	phosphoesterase, PA-phosphatase related
PF986_RS05460	COG1509	lysine 2,3-aminomutase activity
PF986_RS05465	COG0456	acetyltransferase
PF986_RS05470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PF986_RS05475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PF986_RS05480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PF986_RS05485	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PF986_RS05490	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
PF986_RS05500	COG0456	acetyltransferase
PF986_RS05505	COG0463	Glycosyl transferase, family 2
PF986_RS05520	COG4641	Protein conserved in bacteria
PF986_RS05530	COG1086	Polysaccharide biosynthesis protein
PF986_RS05555	COG0457	Tetratricopeptide repeat
PF986_RS05560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PF986_RS05580	COG3391	amine dehydrogenase activity
PF986_RS05585	COG3328	transposase activity
PF986_RS05615	COG5444	nuclease activity
PF986_RS05620	COG4282	regulation of fungal-type cell wall biogenesis
PF986_RS05625	COG1525	nuclease
PF986_RS05655	COG1846	Transcriptional regulator
PF986_RS05660	COG4698	Protein conserved in bacteria
PF986_RS05665	COG2755	lipolytic protein G-D-S-L family
PF986_RS05670	COG1999	signal sequence binding
PF986_RS05680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PF986_RS05685	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PF986_RS05690	COG1272	protein, Hemolysin III
PF986_RS05695	COG0204	Acyl-transferase
PF986_RS05700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PF986_RS05715	COG2136	Putative SAM-dependent methyltransferase
PF986_RS05715	COG2521	methyltransferase
PF986_RS05730	COG1413	lyase activity
PF986_RS05735	COG1418	mRNA catabolic process
PF986_RS05740	COG0386	Belongs to the glutathione peroxidase family
PF986_RS05750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PF986_RS05760	COG1278	Cold shock
PF986_RS05780	COG0328	RNA-DNA hybrid ribonuclease activity
PF986_RS05785	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PF986_RS05790	COG0328	RNA-DNA hybrid ribonuclease activity
PF986_RS05800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PF986_RS05815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PF986_RS05825	COG1755	Isoprenylcysteine carboxyl methyltransferase
PF986_RS05830	COG3424	synthase
PF986_RS05850	COG2323	membrane
PF986_RS05855	COG1335	isochorismatase
PF986_RS05860	COG2233	PERMEase
PF986_RS05870	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PF986_RS05875	COG1199	ATP-dependent helicase activity
PF986_RS05890	COG0116	Belongs to the methyltransferase superfamily
PF986_RS05920	COG3359	exonuclease
PF986_RS05925	COG1111	helicase
PF986_RS05925	COG1205	dead DEAH box helicase
PF986_RS05930	COG2190	(PTS) system
PF986_RS05935	COG0071	Belongs to the small heat shock protein (HSP20) family
PF986_RS05975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PF986_RS05975	COG4499	WXG100 protein secretion system (Wss), protein YukC
PF986_RS05985	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PF986_RS05990	COG3935	DnaD domain protein
PF986_RS06000	COG0436	Aminotransferase
PF986_RS06005	COG5353	protein conserved in bacteria
PF986_RS06015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PF986_RS06015	COG1199	ATP-dependent helicase activity
PF986_RS06045	COG0438	transferase activity, transferring glycosyl groups
PF986_RS06050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PF986_RS06065	COG1694	Mazg nucleotide pyrophosphohydrolase
PF986_RS06070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS06075	COG2140	Oxalate decarboxylase
PF986_RS06085	COG4347	Protein of unknown function (DUF1405)
PF986_RS06090	COG2010	Cytochrome c
PF986_RS06090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PF986_RS06095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PF986_RS06100	COG0723	plastoquinol--plastocyanin reductase activity
PF986_RS06115	COG0457	Tetratricopeptide repeat
PF986_RS06125	COG0287	Prephenate dehydrogenase
PF986_RS06160	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PF986_RS06165	COG4401	Chorismate mutase type I
PF986_RS06180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PF986_RS06185	COG0105	UTP biosynthetic process
PF986_RS06190	COG0142	geranyltranstransferase activity
PF986_RS06200	COG0142	geranyltranstransferase activity
PF986_RS06215	COG0776	regulation of translation
PF986_RS06220	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PF986_RS06260	COG0539	negative regulation of cytoplasmic translation
PF986_RS06275	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PF986_RS06280	COG2959	enzyme of heme biosynthesis
PF986_RS06285	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS06285	COG3773	Cell wall hydrolase
PF986_RS06290	COG2339	peptidase activity
PF986_RS06295	COG0492	ferredoxin-NADP+ reductase activity
PF986_RS06300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PF986_RS06305	COG4862	establishment of competence for transformation
PF986_RS06310	COG1408	metallophosphoesterase
PF986_RS06320	COG1388	LysM domain
PF986_RS06325	COG1266	CAAX protease self-immunity
PF986_RS06330	COG0514	ATP-dependent DNA helicase (RecQ)
PF986_RS06335	COG4955	Helix-turn-helix domain
PF986_RS06340	COG1141	Ferredoxin
PF986_RS06345	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PF986_RS06350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PF986_RS06360	COG1595	DNA-templated transcription, initiation
PF986_RS06365	COG5002	protein histidine kinase activity
PF986_RS06370	COG0745	RESPONSE REGULATOR receiver
PF986_RS06375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PF986_RS06380	COG1333	cytochrome c biogenesis protein
PF986_RS06385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS06390	COG1187	pseudouridine synthase activity
PF986_RS06395	COG0700	Nucleoside recognition
PF986_RS06400	COG2715	membrane protein required for spore maturation
PF986_RS06405	COG1686	Belongs to the peptidase S11 family
PF986_RS06430	COG1547	Domain of unknown function (DUF309)
PF986_RS06435	COG0456	acetyltransferase
PF986_RS06450	COG0307	riboflavin synthase, alpha
PF986_RS06455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PF986_RS06455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PF986_RS06465	COG0681	Belongs to the peptidase S26 family
PF986_RS06475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PF986_RS06480	COG4086	secreted protein
PF986_RS06485	COG0019	diaminopimelate decarboxylase activity
PF986_RS06490	COG0697	spore germination
PF986_RS06505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PF986_RS06525	COG1191	sigma factor activity
PF986_RS06535	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS06540	COG1686	Belongs to the peptidase S11 family
PF986_RS06545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PF986_RS06550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PF986_RS06555	COG4974	Belongs to the 'phage' integrase family
PF986_RS06565	COG0735	belongs to the Fur family
PF986_RS06570	COG1300	Membrane
PF986_RS06585	COG0281	malic enzyme
PF986_RS06590	COG1757	Na H antiporter
PF986_RS06595	COG1027	Aspartate ammonia-lyase
PF986_RS06600	COG0252	asparaginase activity
PF986_RS06605	COG1396	sequence-specific DNA binding
PF986_RS06610	COG1379	DNA repair
PF986_RS06615	COG0494	nUDIX hydrolase
PF986_RS06625	COG0667	Aldo Keto reductase
PF986_RS06635	COG1073	alpha beta
PF986_RS06645	COG4918	Iron-sulphur cluster biosynthesis
PF986_RS06650	COG0456	acetyltransferase
PF986_RS06650	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PF986_RS06655	COG2329	Antibiotic biosynthesis monooxygenase
PF986_RS06660	COG0456	acetyltransferase
PF986_RS06665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PF986_RS06680	COG0628	permease
PF986_RS06690	COG0346	lactoylglutathione lyase activity
PF986_RS06705	COG0300	oxidoreductase activity
PF986_RS06710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS06715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PF986_RS06720	COG1024	Enoyl-CoA hydratase
PF986_RS06725	COG3425	synthase
PF986_RS06730	COG2124	cytochrome p450
PF986_RS06735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS06735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS06735	COG3321	synthase
PF986_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS06740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS06740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06740	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06740	COG3321	synthase
PF986_RS06745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06745	COG0300	oxidoreductase activity
PF986_RS06745	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06745	COG3321	synthase
PF986_RS06750	COG0300	oxidoreductase activity
PF986_RS06750	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS06750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06750	COG3321	synthase
PF986_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06755	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS06755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS06755	COG3321	synthase
PF986_RS06760	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS06760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06760	COG3321	synthase
PF986_RS06760	COG0300	oxidoreductase activity
PF986_RS06765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PF986_RS06765	COG3321	synthase
PF986_RS06765	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS06765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS06770	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS06775	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS06790	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PF986_RS06790	COG2070	2-Nitropropane dioxygenase
PF986_RS06795	COG0250	Participates in transcription elongation, termination and antitermination
PF986_RS06820	COG0596	Alpha beta hydrolase
PF986_RS06835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PF986_RS06840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PF986_RS06855	COG0706	membrane insertase activity
PF986_RS06860	COG2195	Cleaves the N-terminal amino acid of tripeptides
PF986_RS06865	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PF986_RS06870	COG0346	lactoylglutathione lyase activity
PF986_RS06880	COG1376	ErfK ybiS ycfS ynhG family protein
PF986_RS06885	COG4129	membrane
PF986_RS06890	COG1126	abc transporter atp-binding protein
PF986_RS06895	COG0765	amino acid transport
PF986_RS06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS06915	COG1597	lipid kinase activity
PF986_RS06920	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF986_RS06925	COG0022	dehydrogenase e1 component
PF986_RS06930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PF986_RS06935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF986_RS06940	COG3426	butyrate kinase activity
PF986_RS06945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PF986_RS06950	COG0280	phosphate acetyltransferase
PF986_RS06955	COG3290	protein histidine kinase activity
PF986_RS06955	COG3829	transcription factor binding
PF986_RS06965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PF986_RS06970	COG2079	MmgE PrpD family protein
PF986_RS06975	COG0372	Belongs to the citrate synthase family
PF986_RS06980	COG1960	acyl-CoA dehydrogenase activity
PF986_RS06985	COG1250	3-hydroxyacyl-CoA dehydrogenase
PF986_RS06990	COG0183	Belongs to the thiolase family
PF986_RS06995	COG0584	glycerophosphoryl diester phosphodiesterase
PF986_RS07000	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS07025	COG1902	pentaerythritol trinitrate reductase activity
PF986_RS07040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PF986_RS07045	COG0745	RESPONSE REGULATOR receiver
PF986_RS07050	COG0750	zinc metalloprotease
PF986_RS07055	COG0497	DNA recombination
PF986_RS07065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PF986_RS07075	COG0142	geranyltranstransferase activity
PF986_RS07085	COG1570	exodeoxyribonuclease VII activity
PF986_RS07100	COG1302	Protein conserved in bacteria
PF986_RS07105	COG0439	Biotin carboxylase
PF986_RS07110	COG0511	ligase activity, forming carbon-carbon bonds
PF986_RS07150	COG3854	ATPases associated with a variety of cellular activities
PF986_RS07165	COG0006	proline dipeptidase activity
PF986_RS07175	COG3872	metal-dependent enzyme
PF986_RS07185	COG1752	Esterase of the alpha-beta hydrolase superfamily
PF986_RS07200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PF986_RS07220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PF986_RS07235	COG1396	sequence-specific DNA binding
PF986_RS07245	COG0681	Belongs to the peptidase S26 family
PF986_RS07270	COG4940	Competence protein ComGF
PF986_RS07280	COG4970	Tfp pilus assembly protein FimT
PF986_RS07285	COG4537	Required for transformation and DNA binding
PF986_RS07290	COG1459	type II secretion system
PF986_RS07295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PF986_RS07300	COG0598	Magnesium transport protein CorA
PF986_RS07305	COG1253	flavin adenine dinucleotide binding
PF986_RS07310	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS07320	COG1393	Belongs to the ArsC family
PF986_RS07330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS07340	COG0011	TIGRFAM Protein of
PF986_RS07350	COG2866	Carboxypeptidase
PF986_RS07355	COG1940	carbohydrate kinase activity
PF986_RS07360	COG4483	Protein conserved in bacteria
PF986_RS07365	COG1757	Na H antiporter
PF986_RS07375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PF986_RS07390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PF986_RS07395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PF986_RS07400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PF986_RS07405	COG0581	inorganic phosphate transmembrane transporter activity
PF986_RS07410	COG0573	inorganic phosphate transmembrane transporter activity
PF986_RS07415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PF986_RS07420	COG0768	penicillin binding
PF986_RS07425	COG0477	Major facilitator Superfamily
PF986_RS07430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PF986_RS07435	COG2839	Protein conserved in bacteria
PF986_RS07440	COG5521	maltodextrose utilization protein MalA
PF986_RS07445	COG1388	LysM domain
PF986_RS07455	COG4709	membrane
PF986_RS07460	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
PF986_RS07465	COG0735	belongs to the Fur family
PF986_RS07470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS07485	COG0513	Belongs to the DEAD box helicase family
PF986_RS07500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PF986_RS07505	COG2384	SAM-dependent methyltransferase
PF986_RS07510	COG2010	Cytochrome c
PF986_RS07515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PF986_RS07520	COG0358	DNA primase activity
PF986_RS07535	COG0517	IMP dehydrogenase activity
PF986_RS07540	COG0751	glycine-tRNA ligase activity
PF986_RS07560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PF986_RS07565	COG0295	cytidine deaminase activity
PF986_RS07570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PF986_RS07580	COG1480	7TM receptor with intracellular HD hydrolase
PF986_RS07585	COG1702	phosphate starvation-inducible protein PhoH
PF986_RS07590	COG0561	phosphatase activity
PF986_RS07605	COG4864	UPF0365 protein
PF986_RS07610	COG1030	water channel activity
PF986_RS07615	COG1610	YqeY-like protein
PF986_RS07625	COG1283	sodium-dependent phosphate transmembrane transporter activity
PF986_RS07630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PF986_RS07635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PF986_RS07665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PF986_RS07680	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS07710	COG0658	competence protein
PF986_RS07710	COG2333	competence protein COMEC
PF986_RS07715	COG2131	deaminase
PF986_RS07720	COG1555	photosystem II stabilization
PF986_RS07720	COG1596	polysaccharide export
PF986_RS07725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PF986_RS07730	COG2226	methyltransferase
PF986_RS07735	COG0799	negative regulation of ribosome biogenesis
PF986_RS07740	COG1713	HD superfamily hydrolase involved in NAD metabolism
PF986_RS07750	COG1534	Rna-binding protein
PF986_RS07755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PF986_RS07760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PF986_RS07765	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
PF986_RS07780	COG2755	lipolytic protein G-D-S-L family
PF986_RS07790	COG0398	Pfam SNARE associated Golgi protein
PF986_RS07815	COG1794	racemase activity, acting on amino acids and derivatives
PF986_RS07830	COG0656	L-ascorbic acid biosynthetic process
PF986_RS07860	COG5444	nuclease activity
PF986_RS07865	COG4282	regulation of fungal-type cell wall biogenesis
PF986_RS07885	COG0583	DNA-binding transcription factor activity
PF986_RS07900	COG0642	Histidine kinase
PF986_RS07900	COG5002	protein histidine kinase activity
PF986_RS07905	COG0745	RESPONSE REGULATOR receiver
PF986_RS07910	COG2311	Membrane
PF986_RS07915	COG0454	-acetyltransferase
PF986_RS07920	COG0563	adenylate kinase activity
PF986_RS07930	COG2814	Major facilitator Superfamily
PF986_RS07950	COG5444	nuclease activity
PF986_RS07970	COG3328	transposase activity
PF986_RS07985	COG0456	acetyltransferase
PF986_RS07990	COG2318	DinB family
PF986_RS08000	COG0561	phosphatase activity
PF986_RS08005	COG0561	phosphatase activity
PF986_RS08015	COG1482	cell wall glycoprotein biosynthetic process
PF986_RS08020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS08020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF986_RS08020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PF986_RS08025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS08025	COG3711	transcriptional antiterminator
PF986_RS08035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PF986_RS08040	COG0583	DNA-binding transcription factor activity
PF986_RS08045	COG2814	Major facilitator Superfamily
PF986_RS08050	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PF986_RS08050	COG2124	cytochrome p450
PF986_RS08055	COG1309	transcriptional regulator
PF986_RS08060	COG2226	methyltransferase
PF986_RS08075	COG2116	formate transmembrane transporter activity
PF986_RS08080	COG5609	conserved protein (DUF2294)
PF986_RS08085	COG3383	formate dehydrogenase (NAD+) activity
PF986_RS08090	COG2427	Protein of unknown function (DUF1641)
PF986_RS08100	COG0626	cystathionine gamma-synthase activity
PF986_RS08105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PF986_RS08130	COG0768	penicillin binding
PF986_RS08145	COG0826	peptidase U32
PF986_RS08150	COG0826	peptidase U32
PF986_RS08155	COG4122	O-methyltransferase activity
PF986_RS08160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PF986_RS08175	COG4472	Bacterial protein of unknown function (DUF965)
PF986_RS08185	COG0628	permease
PF986_RS08190	COG1126	abc transporter atp-binding protein
PF986_RS08195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS08200	COG0765	amino acid transport
PF986_RS08205	COG0765	amino acid transport
PF986_RS08220	COG3881	PFAM PRC-barrel domain
PF986_RS08225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PF986_RS08230	COG0457	Tetratricopeptide repeat
PF986_RS08240	COG1104	cysteine desulfurase activity
PF986_RS08245	COG1959	2 iron, 2 sulfur cluster binding
PF986_RS08250	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PF986_RS08255	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PF986_RS08280	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS08280	COG3103	Sh3 type 3 domain protein
PF986_RS08280	COG4991	sh3 domain protein
PF986_RS08290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PF986_RS08300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PF986_RS08300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PF986_RS08305	COG5416	Lipopolysaccharide assembly protein A domain
PF986_RS08310	COG0490	domain, Protein
PF986_RS08315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PF986_RS08315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PF986_RS08325	COG2244	polysaccharide biosynthetic process
PF986_RS08330	COG2323	membrane
PF986_RS08340	COG1862	Preprotein translocase
PF986_RS08380	COG1388	LysM domain
PF986_RS08390	COG0157	Belongs to the NadC ModD family
PF986_RS08395	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PF986_RS08400	COG1104	cysteine desulfurase activity
PF986_RS08405	COG1827	regulation of RNA biosynthetic process
PF986_RS08410	COG0077	Prephenate dehydratase
PF986_RS08425	COG3290	protein histidine kinase activity
PF986_RS08430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PF986_RS08435	COG2868	ribosomal protein
PF986_RS08445	COG1994	Peptidase M50
PF986_RS08450	COG0739	heme binding
PF986_RS08455	COG2894	cell division
PF986_RS08465	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PF986_RS08475	COG1077	Cell shape determining protein MreB Mrl
PF986_RS08495	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PF986_RS08500	COG0285	dihydrofolate synthase activity
PF986_RS08505	COG0525	valine-tRNA ligase activity
PF986_RS08515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PF986_RS08520	COG1388	LysM domain
PF986_RS08530	COG0113	porphobilinogen synthase activity
PF986_RS08535	COG1587	Uroporphyrinogen-III synthase
PF986_RS08545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PF986_RS08565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PF986_RS08570	COG1067	ATP-dependent peptidase activity
PF986_RS08570	COG0470	DNA polymerase III
PF986_RS08585	COG1477	protein flavinylation
PF986_RS08585	COG0457	Tetratricopeptide repeat
PF986_RS08600	COG0473	3-isopropylmalate dehydrogenase activity
PF986_RS08615	COG0440	acetolactate synthase activity
PF986_RS08620	COG0028	Belongs to the TPP enzyme family
PF986_RS08650	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PF986_RS08670	COG0622	Phosphoesterase
PF986_RS08675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PF986_RS08685	COG5401	PFAM Sporulation and spore germination
PF986_RS08700	COG2197	response regulator
PF986_RS08705	COG0824	Thioesterase
PF986_RS08710	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PF986_RS08715	COG1053	succinate dehydrogenase
PF986_RS08720	COG2009	succinate dehydrogenase
PF986_RS08725	COG1719	4-vinyl reductase, 4VR
PF986_RS08730	COG0527	aspartate kinase activity
PF986_RS08740	COG3118	belongs to the thioredoxin family
PF986_RS08745	COG3534	alpha-L-arabinofuranosidase
PF986_RS08750	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PF986_RS08755	COG2086	electron transfer activity
PF986_RS08760	COG1024	Enoyl-CoA hydratase
PF986_RS08765	COG1309	transcriptional regulator
PF986_RS08770	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS08780	COG3766	membrane
PF986_RS08790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PF986_RS08790	COG1796	DNA polymerase
PF986_RS08795	COG1286	toxin biosynthetic process
PF986_RS08810	COG0072	phenylalanine-tRNA ligase activity
PF986_RS08810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF986_RS08815	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PF986_RS08820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PF986_RS08830	COG3835	regulator
PF986_RS08835	COG0277	FAD linked oxidase domain protein
PF986_RS08840	COG0247	lactate metabolic process
PF986_RS08845	COG1966	Carbon starvation protein
PF986_RS08850	COG3534	alpha-L-arabinofuranosidase
PF986_RS08855	COG0395	ABC-type sugar transport system, permease component
PF986_RS08860	COG1175	transmembrane transport
PF986_RS08865	COG1653	transport
PF986_RS08875	COG0647	UMP catabolic process
PF986_RS08880	COG0235	Class ii aldolase
PF986_RS08885	COG1069	ribulokinase activity
PF986_RS08890	COG2160	L-arabinose isomerase activity
PF986_RS08895	COG3507	Belongs to the glycosyl hydrolase 43 family
PF986_RS08900	COG1363	Peptidase, m42
PF986_RS08910	COG3326	Membrane
PF986_RS08925	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PF986_RS08930	COG1346	cytolysis
PF986_RS08935	COG1380	Effector of murein hydrolase LrgA
PF986_RS08940	COG3279	Response regulator of the LytR AlgR family
PF986_RS08945	COG3275	phosphorelay sensor kinase activity
PF986_RS08950	COG1011	Hydrolase
PF986_RS08965	COG0398	Pfam SNARE associated Golgi protein
PF986_RS08970	COG1484	DNA-dependent DNA replication
PF986_RS08975	COG3611	Membrane attachment protein
PF986_RS08990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PF986_RS08995	COG1733	regulation of RNA biosynthetic process
PF986_RS09000	COG2814	Major facilitator Superfamily
PF986_RS09005	COG0656	L-ascorbic acid biosynthetic process
PF986_RS09010	COG0237	dephospho-CoA kinase activity
PF986_RS09015	COG1971	Probably functions as a manganese efflux pump
PF986_RS09020	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PF986_RS09025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PF986_RS09025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PF986_RS09030	COG5002	protein histidine kinase activity
PF986_RS09035	COG0745	RESPONSE REGULATOR receiver
PF986_RS09045	COG0538	isocitrate dehydrogenase activity
PF986_RS09050	COG0372	Belongs to the citrate synthase family
PF986_RS09060	COG0457	Tetratricopeptide repeat
PF986_RS09090	COG0628	permease
PF986_RS09095	COG3030	protein affecting phage T7 exclusion by the F plasmid
PF986_RS09100	COG0469	pyruvate kinase activity
PF986_RS09120	COG0281	malic enzyme
PF986_RS09125	COG0587	DNA-directed DNA polymerase activity
PF986_RS09145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PF986_RS09155	COG4109	DRTGG domain
PF986_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS09185	COG0521	Mo-molybdopterin cofactor biosynthetic process
PF986_RS09195	COG0827	DNA restriction-modification system
PF986_RS09200	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PF986_RS09205	COG3874	Sporulation protein YtfJ
PF986_RS09215	COG1714	RDD family
PF986_RS09220	COG0616	signal peptide processing
PF986_RS09225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PF986_RS09230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PF986_RS09235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PF986_RS09250	COG1104	cysteine desulfurase activity
PF986_RS09255	COG1114	Component of the transport system for branched-chain amino acids
PF986_RS09265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PF986_RS09270	COG1309	transcriptional regulator
PF986_RS09275	COG1956	GAF domain-containing protein
PF986_RS09280	COG2203	Gaf domain
PF986_RS09280	COG2199	diguanylate cyclase activity
PF986_RS09290	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS09295	COG4282	regulation of fungal-type cell wall biogenesis
PF986_RS09345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF986_RS09345	COG1017	nitric oxide dioxygenase activity
PF986_RS09355	COG0693	protein deglycase activity
PF986_RS09375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PF986_RS09380	COG1378	Sugar-specific transcriptional regulator TrmB
PF986_RS09405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PF986_RS09410	COG0454	-acetyltransferase
PF986_RS09415	COG0517	IMP dehydrogenase activity
PF986_RS09420	COG0123	including yeast histone deacetylase and acetoin utilization protein
PF986_RS09425	COG1360	Flagellar Motor Protein
PF986_RS09430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PF986_RS09435	COG1609	Transcriptional regulator
PF986_RS09440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PF986_RS09440	COG1605	Chorismate mutase
PF986_RS09445	COG3118	belongs to the thioredoxin family
PF986_RS09450	COG4980	gas vesicle protein
PF986_RS09455	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PF986_RS09465	COG1674	ftsk spoiiie
PF986_RS09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF986_RS09480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS09490	COG1363	Peptidase, m42
PF986_RS09495	COG5584	Small secreted protein
PF986_RS09500	COG0281	malic enzyme
PF986_RS09505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS09520	COG0510	thiamine kinase activity
PF986_RS09525	COG1597	lipid kinase activity
PF986_RS09535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PF986_RS09540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PF986_RS09545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PF986_RS09550	COG2252	PERMEase
PF986_RS09555	COG4473	ABC transporter
PF986_RS09560	COG1131	(ABC) transporter
PF986_RS09565	COG1349	DNA-binding transcription factor activity
PF986_RS09575	COG1187	pseudouridine synthase activity
PF986_RS09580	COG2244	polysaccharide biosynthetic process
PF986_RS09585	COG2081	HI0933 family
PF986_RS09590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PF986_RS09600	COG1609	Transcriptional regulator
PF986_RS09605	COG1653	transport
PF986_RS09610	COG1175	transmembrane transport
PF986_RS09615	COG0395	ABC-type sugar transport system, permease component
PF986_RS09620	COG1486	melibiose metabolic process
PF986_RS09630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PF986_RS09645	COG2202	Pas domain
PF986_RS09645	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS09650	COG2814	Major facilitator Superfamily
PF986_RS09655	COG5522	Integral membrane protein (intg_mem_TP0381)
PF986_RS09660	COG0577	efflux transmembrane transporter activity
PF986_RS09665	COG1136	(ABC) transporter
PF986_RS09670	COG2205	protein histidine kinase activity
PF986_RS09675	COG0745	RESPONSE REGULATOR receiver
PF986_RS09680	COG0577	efflux transmembrane transporter activity
PF986_RS09685	COG1136	(ABC) transporter
PF986_RS09705	COG1131	(ABC) transporter
PF986_RS09710	COG1725	Transcriptional regulator
PF986_RS09725	COG0640	Transcriptional regulator
PF986_RS09730	COG0477	Major facilitator Superfamily
PF986_RS09735	COG1242	4 iron, 4 sulfur cluster binding
PF986_RS09740	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PF986_RS09750	COG0584	glycerophosphoryl diester phosphodiesterase
PF986_RS09760	COG2267	carboxylic ester hydrolase activity
PF986_RS09765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PF986_RS09770	COG1113	amino acid transport
PF986_RS09775	COG0367	asparagine synthase
PF986_RS09795	COG1506	peptidase
PF986_RS09800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PF986_RS09805	COG1116	anion transmembrane transporter activity
PF986_RS09810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PF986_RS09815	COG0494	nUDIX hydrolase
PF986_RS09820	COG4824	toxin secretion phage lysis holin
PF986_RS09825	COG0783	Belongs to the Dps family
PF986_RS09850	COG0288	reversible hydration of carbon dioxide
PF986_RS09860	COG1271	oxidase subunit
PF986_RS09865	COG1294	oxidase, subunit
PF986_RS09875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PF986_RS09880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PF986_RS09880	COG1321	iron dependent repressor
PF986_RS09885	COG1121	(ABC) transporter
PF986_RS09890	COG0803	Belongs to the bacterial solute-binding protein 9 family
PF986_RS09895	COG4948	Mandelate Racemase Muconate Lactonizing
PF986_RS09905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PF986_RS09910	COG0596	Alpha beta hydrolase
PF986_RS09920	COG1169	isochorismate synthase
PF986_RS09925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PF986_RS09930	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
PF986_RS10055	COG3859	Proton-coupled thiamine transporter YuaJ
PF986_RS10060	COG2268	Band 7 protein
PF986_RS10065	COG1585	Membrane protein implicated in regulation of membrane protease activity
PF986_RS10070	COG2318	DinB family
PF986_RS10080	COG1454	alcohol dehydrogenase
PF986_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS10090	COG1510	regulation of RNA biosynthetic process
PF986_RS10100	COG0569	domain protein
PF986_RS10105	COG1705	Flagellar rod assembly protein muramidase FlgJ
PF986_RS10110	COG1017	nitric oxide dioxygenase activity
PF986_RS10110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PF986_RS10140	COG5444	nuclease activity
PF986_RS10155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PF986_RS10170	COG0628	permease
PF986_RS10175	COG0673	inositol 2-dehydrogenase activity
PF986_RS10180	COG0693	protein deglycase activity
PF986_RS10185	COG0840	transmembrane signaling receptor activity
PF986_RS10195	COG0840	transmembrane signaling receptor activity
PF986_RS10200	COG0840	transmembrane signaling receptor activity
PF986_RS10215	COG2070	2-Nitropropane dioxygenase
PF986_RS10220	COG0432	Pfam Uncharacterised protein family UPF0047
PF986_RS10225	COG0366	Alpha amylase catalytic
PF986_RS10230	COG1253	flavin adenine dinucleotide binding
PF986_RS10235	COG2738	Putative neutral zinc metallopeptidase
PF986_RS10250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PF986_RS10275	COG1335	isochorismatase
PF986_RS10280	COG1979	alcohol dehydrogenase
PF986_RS10285	COG1979	alcohol dehydrogenase
PF986_RS10290	COG2155	Conserved Protein
PF986_RS10295	COG1098	S1 RNA binding domain
PF986_RS10300	COG0436	Aminotransferase
PF986_RS10305	COG1522	sequence-specific DNA binding
PF986_RS10310	COG2267	carboxylic ester hydrolase activity
PF986_RS10320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PF986_RS10325	COG2205	protein histidine kinase activity
PF986_RS10335	COG5018	Exonuclease
PF986_RS10340	COG2814	Major facilitator Superfamily
PF986_RS10345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PF986_RS10350	COG3011	Protein conserved in bacteria
PF986_RS10360	COG3290	protein histidine kinase activity
PF986_RS10365	COG4565	transcriptional regulatory protein
PF986_RS10370	COG1744	ABC transporter substrate-binding protein PnrA-like
PF986_RS10375	COG3845	ABC transporter
PF986_RS10380	COG4603	Belongs to the binding-protein-dependent transport system permease family
PF986_RS10385	COG1079	Belongs to the binding-protein-dependent transport system permease family
PF986_RS10395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PF986_RS10395	COG2111	Na H antiporter
PF986_RS10400	COG2111	Na H antiporter
PF986_RS10405	COG1006	Multisubunit Na H antiporter MnhC subunit
PF986_RS10410	COG0651	ATP synthesis coupled electron transport
PF986_RS10415	COG1863	multisubunit Na H antiporter MnhE subunit
PF986_RS10420	COG2212	antiporter activity
PF986_RS10425	COG1320	monovalent cation:proton antiporter activity
PF986_RS10430	COG2050	protein possibly involved in aromatic compounds catabolism
PF986_RS10435	COG2197	response regulator
PF986_RS10440	COG4585	Histidine kinase
PF986_RS10450	COG0142	geranyltranstransferase activity
PF986_RS10465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
PF986_RS10470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PF986_RS10475	COG1335	isochorismatase
PF986_RS10480	COG5506	Protein of unknown function (DUF1694)
PF986_RS10495	COG0628	permease
PF986_RS10505	COG1418	mRNA catabolic process
PF986_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS10520	COG1511	domain protein
PF986_RS10525	COG0433	COG0433 Predicted ATPase
PF986_RS10525	COG1674	ftsk spoiiie
PF986_RS10530	COG4499	WXG100 protein secretion system (Wss), protein YukC
PF986_RS10535	COG5417	Belongs to the EsaB family
PF986_RS10540	COG4842	Belongs to the WXG100 family
PF986_RS10545	COG2508	Transcriptional regulator
PF986_RS10545	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PF986_RS10550	COG0686	Belongs to the AlaDH PNT family
PF986_RS10555	COG5634	Uncharacterized conserved protein (DUF2278)
PF986_RS10560	COG3251	PFAM MbtH domain protein
PF986_RS10565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS10570	COG1535	isochorismatase
PF986_RS10570	COG3433	isochorismatase activity
PF986_RS10575	COG1021	2,3-dihydroxybenzoate-AMP ligase
PF986_RS10580	COG1169	isochorismate synthase
PF986_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS10590	COG2819	hydrolase of the alpha beta superfamily
PF986_RS10595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PF986_RS10600	COG1268	BioY protein
PF986_RS10605	COG2056	Na+-H+ antiporter family
PF986_RS10615	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
PF986_RS10620	COG3584	3D domain protein
PF986_RS10635	COG1252	NADH dehydrogenase
PF986_RS10665	COG1131	(ABC) transporter
PF986_RS10685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PF986_RS10690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PF986_RS10695	COG0316	Belongs to the HesB IscA family
PF986_RS10705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PF986_RS10715	COG1252	NADH dehydrogenase
PF986_RS10720	COG4837	Protein of unknown function (DUF1462)
PF986_RS10725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PF986_RS10730	COG0823	Involved in the tonB-independent uptake of proteins
PF986_RS10730	COG1506	peptidase
PF986_RS10730	COG4946	Tricorn protease homolog
PF986_RS10740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PF986_RS10745	COG0460	homoserine dehydrogenase
PF986_RS10750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PF986_RS10755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PF986_RS10760	COG0647	UMP catabolic process
PF986_RS10765	COG2445	Protein of unknown function DUF86
PF986_RS10770	COG4470	Protein conserved in bacteria
PF986_RS10780	COG0739	heme binding
PF986_RS10790	COG0737	Belongs to the 5'-nucleotidase family
PF986_RS10795	COG0730	response to heat
PF986_RS10800	COG1801	Protein of unknown function DUF72
PF986_RS10815	COG2508	Transcriptional regulator
PF986_RS10820	COG0457	Tetratricopeptide repeat
PF986_RS10835	COG2814	Major facilitator Superfamily
PF986_RS10840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PF986_RS10845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PF986_RS10850	COG2356	endonuclease I
PF986_RS10855	COG3842	ATPase activity
PF986_RS10860	COG2188	Transcriptional regulator
PF986_RS10865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PF986_RS10870	COG0395	ABC-type sugar transport system, permease component
PF986_RS10875	COG1175	transmembrane transport
PF986_RS10880	COG1653	transport
PF986_RS10885	COG2222	sugar isomerase
PF986_RS10890	COG0789	Transcriptional regulator
PF986_RS10915	COG0322	excinuclease ABC activity
PF986_RS10920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PF986_RS10925	COG2226	methyltransferase
PF986_RS10935	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS10940	COG0719	Fe-S assembly protein
PF986_RS10945	COG0822	iron-sulfur transferase activity
PF986_RS10950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PF986_RS10955	COG0719	Fe-S assembly protein
PF986_RS10960	COG0396	ATPase activity
PF986_RS10970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PF986_RS10975	COG1464	Belongs to the NlpA lipoprotein family
PF986_RS10980	COG2011	ABC-type metal ion transport system permease component
PF986_RS10985	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PF986_RS10995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS11000	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PF986_RS11015	COG1393	Belongs to the ArsC family
PF986_RS11020	COG1960	acyl-CoA dehydrogenase activity
PF986_RS11025	COG0183	Belongs to the thiolase family
PF986_RS11030	COG1024	Enoyl-CoA hydratase
PF986_RS11030	COG1250	3-hydroxyacyl-CoA dehydrogenase
PF986_RS11050	COG5577	PFAM Coat F domain
PF986_RS11055	COG1846	Transcriptional regulator
PF986_RS11060	COG0477	Major facilitator Superfamily
PF986_RS11090	COG1120	ATPase activity
PF986_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS11110	COG0783	Belongs to the Dps family
PF986_RS11115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF986_RS11120	COG0745	RESPONSE REGULATOR receiver
PF986_RS11125	COG2770	Histidine kinase
PF986_RS11125	COG2205	protein histidine kinase activity
PF986_RS11135	COG1309	transcriptional regulator
PF986_RS11140	COG0114	fumarate hydratase activity
PF986_RS11150	COG0697	spore germination
PF986_RS11155	COG0814	amino acid
PF986_RS11165	COG2197	response regulator
PF986_RS11170	COG4585	Histidine kinase
PF986_RS11175	COG4758	membrane
PF986_RS11180	COG3595	metallopeptidase activity
PF986_RS11185	COG1842	Phage shock protein A
PF986_RS11190	COG4758	membrane
PF986_RS11195	COG2814	Major facilitator Superfamily
PF986_RS11200	COG2096	Adenosyltransferase
PF986_RS11205	COG1120	ATPase activity
PF986_RS11210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS11215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PF986_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS11225	COG3386	PFAM SMP-30 Gluconolaconase
PF986_RS11230	COG2205	protein histidine kinase activity
PF986_RS11235	COG0745	RESPONSE REGULATOR receiver
PF986_RS11245	COG1191	sigma factor activity
PF986_RS11255	COG2140	Oxalate decarboxylase
PF986_RS11265	COG1120	ATPase activity
PF986_RS11270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS11275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS11280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PF986_RS11285	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PF986_RS11290	COG0531	amino acid
PF986_RS11300	COG1988	membrane-bound metal-dependent
PF986_RS11305	COG1368	sulfuric ester hydrolase activity
PF986_RS11310	COG1910	domain protein
PF986_RS11315	COG0725	ABC transporter, periplasmic molybdate-binding protein
PF986_RS11320	COG4149	molybdate abc transporter
PF986_RS11325	COG2197	response regulator
PF986_RS11330	COG3850	Histidine kinase
PF986_RS11335	COG1131	(ABC) transporter
PF986_RS11345	COG0842	Transport permease protein
PF986_RS11350	COG0656	L-ascorbic acid biosynthetic process
PF986_RS11370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PF986_RS11375	COG3973	AAA domain
PF986_RS11380	COG2860	membrane
PF986_RS11390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PF986_RS11395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PF986_RS11400	COG2217	Heavy metal translocating P-type atpase
PF986_RS11405	COG2217	Heavy metal translocating P-type atpase
PF986_RS11410	COG2608	mercury ion transmembrane transporter activity
PF986_RS11415	COG1937	Protein conserved in bacteria
PF986_RS11420	COG0673	inositol 2-dehydrogenase activity
PF986_RS11430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS11435	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PF986_RS11440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS11450	COG0765	amino acid transport
PF986_RS11455	COG0765	amino acid transport
PF986_RS11460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS11465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS11470	COG0454	-acetyltransferase
PF986_RS11480	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS11485	COG2732	(Barnase) inhibitor
PF986_RS11490	COG2732	(Barnase) inhibitor
PF986_RS11510	COG4824	toxin secretion phage lysis holin
PF986_RS11530	COG5434	Belongs to the glycosyl hydrolase 28 family
PF986_RS11535	COG1388	LysM domain
PF986_RS11535	COG1705	Flagellar rod assembly protein muramidase FlgJ
PF986_RS11610	COG4626	Terminase
PF986_RS11610	COG1802	Transcriptional regulator
PF986_RS11640	COG0582	viral genome integration into host DNA
PF986_RS11645	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PF986_RS11785	COG0582	viral genome integration into host DNA
PF986_RS11800	COG0557	exoribonuclease II activity
PF986_RS11805	COG1647	Serine aminopeptidase, S33
PF986_RS11810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PF986_RS11815	COG1476	TRANSCRIPTIONal
PF986_RS11820	COG1396	sequence-specific DNA binding
PF986_RS11825	COG1396	sequence-specific DNA binding
PF986_RS11830	COG1733	regulation of RNA biosynthetic process
PF986_RS11855	COG1131	(ABC) transporter
PF986_RS11860	COG1174	glycine betaine transport
PF986_RS11865	COG1732	Glycine betaine
PF986_RS11870	COG1174	glycine betaine transport
PF986_RS11875	COG1125	glycine betaine transport
PF986_RS11875	COG0517	IMP dehydrogenase activity
PF986_RS11880	COG1510	regulation of RNA biosynthetic process
PF986_RS11885	COG1174	glycine betaine transport
PF986_RS11890	COG1732	Glycine betaine
PF986_RS11895	COG1174	glycine betaine transport
PF986_RS11900	COG0517	IMP dehydrogenase activity
PF986_RS11900	COG1125	glycine betaine transport
PF986_RS11905	COG1510	regulation of RNA biosynthetic process
PF986_RS11910	COG2095	MarC family integral membrane protein
PF986_RS11915	COG3064	Membrane
PF986_RS11920	COG4640	response to antibiotic
PF986_RS11925	COG0456	acetyltransferase
PF986_RS11945	COG0126	phosphoglycerate kinase activity
PF986_RS11950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PF986_RS11955	COG2390	Transcriptional regulator
PF986_RS11960	COG2814	Major facilitator Superfamily
PF986_RS11965	COG1609	Transcriptional regulator
PF986_RS11970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS11975	COG0583	DNA-binding transcription factor activity
PF986_RS11980	COG0697	spore germination
PF986_RS11985	COG1113	amino acid transport
PF986_RS11995	COG1609	Transcriptional regulator
PF986_RS12005	COG0561	phosphatase activity
PF986_RS12010	COG1737	Transcriptional regulator
PF986_RS12015	COG1070	Carbohydrate kinase
PF986_RS12040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF986_RS12045	COG2186	Transcriptional regulator
PF986_RS12050	COG1620	l-lactate permease
PF986_RS12055	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PF986_RS12065	COG5039	Polysaccharide pyruvyl transferase
PF986_RS12070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PF986_RS12075	COG0110	maltose O-acetyltransferase activity
PF986_RS12080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PF986_RS12085	COG2244	polysaccharide biosynthetic process
PF986_RS12090	COG1216	Glycosyl transferase, family 2
PF986_RS12095	COG5039	Polysaccharide pyruvyl transferase
PF986_RS12100	COG1216	Glycosyl transferase, family 2
PF986_RS12110	COG0438	transferase activity, transferring glycosyl groups
PF986_RS12115	COG1215	transferase activity, transferring glycosyl groups
PF986_RS12120	COG0438	transferase activity, transferring glycosyl groups
PF986_RS12125	COG1086	Polysaccharide biosynthesis protein
PF986_RS12130	COG0489	protein tyrosine kinase activity
PF986_RS12135	COG3944	biosynthesis protein
PF986_RS12140	COG1396	sequence-specific DNA binding
PF986_RS12145	COG2272	Belongs to the type-B carboxylesterase lipase family
PF986_RS12155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PF986_RS12160	COG2364	Membrane
PF986_RS12165	COG0456	acetyltransferase
PF986_RS12170	COG3479	Phenolic acid decarboxylase
PF986_RS12210	COG2223	nitrite transmembrane transporter activity
PF986_RS12215	COG1609	Transcriptional regulator
PF986_RS12225	COG0583	DNA-binding transcription factor activity
PF986_RS12230	COG2828	Protein conserved in bacteria
PF986_RS12235	COG2814	Major facilitator Superfamily
PF986_RS12235	COG0477	Major facilitator Superfamily
PF986_RS12240	COG1611	Belongs to the LOG family
PF986_RS12245	COG1694	Mazg nucleotide pyrophosphohydrolase
PF986_RS12250	COG0659	secondary active sulfate transmembrane transporter activity
PF986_RS12255	COG0288	reversible hydration of carbon dioxide
PF986_RS12260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PF986_RS12265	COG4290	ribonuclease
PF986_RS12270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PF986_RS12275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS12285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PF986_RS12295	COG1051	belongs to the nudix hydrolase family
PF986_RS12300	COG0492	ferredoxin-NADP+ reductase activity
PF986_RS12305	COG3883	PFAM NLP P60 protein
PF986_RS12305	COG0791	NLP P60 protein
PF986_RS12310	COG0457	Tetratricopeptide repeat
PF986_RS12315	COG5002	protein histidine kinase activity
PF986_RS12320	COG0745	RESPONSE REGULATOR receiver
PF986_RS12330	COG1132	(ABC) transporter
PF986_RS12335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PF986_RS12335	COG0140	phosphoribosyl-ATP diphosphatase activity
PF986_RS12360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PF986_RS12375	COG4990	cell redox homeostasis
PF986_RS12380	COG0110	maltose O-acetyltransferase activity
PF986_RS12400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PF986_RS12410	COG2188	Transcriptional regulator
PF986_RS12415	COG1309	transcriptional regulator
PF986_RS12420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PF986_RS12425	COG1950	PFAM Membrane protein of
PF986_RS12430	COG1983	PspC domain protein
PF986_RS12435	COG3595	metallopeptidase activity
PF986_RS12450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PF986_RS12460	COG4897	Protein conserved in bacteria
PF986_RS12465	COG0574	Belongs to the PEP-utilizing enzyme family
PF986_RS12465	COG3848	Pyruvate phosphate dikinase
PF986_RS12470	COG1309	transcriptional regulator
PF986_RS12475	COG2814	Major facilitator Superfamily
PF986_RS12490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF986_RS12500	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS12500	COG0793	Belongs to the peptidase S41A family
PF986_RS12505	COG3420	alginic acid biosynthetic process
PF986_RS12510	COG2177	Part of the ABC transporter FtsEX involved in
PF986_RS12515	COG2884	Cell division ATP-binding protein ftsE
PF986_RS12520	COG2010	Cytochrome c
PF986_RS12525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS12540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PF986_RS12555	COG1516	flagellar protein fliS
PF986_RS12560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PF986_RS12565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PF986_RS12585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PF986_RS12590	COG1256	bacterial-type flagellum assembly
PF986_RS12590	COG4786	Flagellar basal body rod
PF986_RS12595	COG3418	PFAM FlgN family protein
PF986_RS12600	COG2747	anti-sigma28 factor FlgM
PF986_RS12610	COG1040	competence protein
PF986_RS12620	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PF986_RS12625	COG1307	EDD domain protein, DegV family
PF986_RS12630	COG2197	response regulator
PF986_RS12635	COG4585	Histidine kinase
PF986_RS12640	COG1739	Uncharacterized protein family UPF0029
PF986_RS12645	COG1316	TRANSCRIPTIONal
PF986_RS12650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PF986_RS12655	COG0438	transferase activity, transferring glycosyl groups
PF986_RS12660	COG1215	transferase activity, transferring glycosyl groups
PF986_RS12665	COG3206	protein involved in exopolysaccharide biosynthesis
PF986_RS12670	COG3307	-O-antigen
PF986_RS12675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PF986_RS12680	COG0438	transferase activity, transferring glycosyl groups
PF986_RS12680	COG0297	glycogen (starch) synthase activity
PF986_RS12685	COG2244	polysaccharide biosynthetic process
PF986_RS12695	COG2247	cell wall binding repeat
PF986_RS12695	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS12710	COG1316	TRANSCRIPTIONal
PF986_RS12715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PF986_RS12720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PF986_RS12725	COG1134	teichoic acid transport
PF986_RS12730	COG1682	transport, permease protein
PF986_RS12735	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PF986_RS12740	COG0438	transferase activity, transferring glycosyl groups
PF986_RS12745	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PF986_RS12750	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PF986_RS12755	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PF986_RS12760	COG4193	domain, Protein
PF986_RS12765	COG1482	cell wall glycoprotein biosynthetic process
PF986_RS12770	COG0697	spore germination
PF986_RS12775	COG0814	amino acid
PF986_RS12785	COG1215	transferase activity, transferring glycosyl groups
PF986_RS12790	COG2814	Major facilitator Superfamily
PF986_RS12795	COG1316	TRANSCRIPTIONal
PF986_RS12800	COG0561	phosphatase activity
PF986_RS12805	COG2433	Pfam Transposase IS66
PF986_RS12810	COG0791	NLP P60 protein
PF986_RS12820	COG2843	Capsule synthesis protein
PF986_RS12830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PF986_RS12835	COG0697	spore germination
PF986_RS12840	COG0814	amino acid
PF986_RS12850	COG1609	Transcriptional regulator
PF986_RS12855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PF986_RS12865	COG1129	ABC transporter
PF986_RS12870	COG1172	Belongs to the binding-protein-dependent transport system permease family
PF986_RS12875	COG1879	ABC-type sugar transport system periplasmic component
PF986_RS12880	COG3103	Sh3 type 3 domain protein
PF986_RS12885	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF986_RS12890	COG3527	Alpha-acetolactate decarboxylase
PF986_RS12895	COG0028	Belongs to the TPP enzyme family
PF986_RS12900	COG0583	DNA-binding transcription factor activity
PF986_RS12905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PF986_RS12920	COG5337	Spore coat protein CotH
PF986_RS12930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PF986_RS12940	COG0405	Gamma-glutamyltransferase
PF986_RS12945	COG1522	sequence-specific DNA binding
PF986_RS12950	COG2059	Chromate
PF986_RS12955	COG2059	Chromate
PF986_RS12965	COG0655	NAD(P)H dehydrogenase (quinone) activity
PF986_RS12970	COG0583	DNA-binding transcription factor activity
PF986_RS13030	COG5444	nuclease activity
PF986_RS13045	COG3878	Protein conserved in bacteria
PF986_RS13050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PF986_RS13055	COG4464	protein tyrosine phosphatase activity
PF986_RS13060	COG0489	protein tyrosine kinase activity
PF986_RS13065	COG3944	biosynthesis protein
PF986_RS13075	COG4715	Zinc finger, swim domain protein
PF986_RS13080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PF986_RS13085	COG0561	phosphatase activity
PF986_RS13090	COG1349	DNA-binding transcription factor activity
PF986_RS13095	COG0629	single-stranded DNA binding
PF986_RS13120	COG0457	Tetratricopeptide repeat
PF986_RS13125	COG4786	Flagellar basal body rod
PF986_RS13130	COG4786	Flagellar basal body rod
PF986_RS13135	COG1077	Cell shape determining protein MreB Mrl
PF986_RS13140	COG1609	Transcriptional regulator
PF986_RS13145	COG1846	Transcriptional regulator
PF986_RS13150	COG2814	Major facilitator Superfamily
PF986_RS13155	COG1953	Uracil, thiamine, allantoin
PF986_RS13160	COG0477	Major facilitator Superfamily
PF986_RS13165	COG1335	isochorismatase
PF986_RS13170	COG0004	ammonium transporteR
PF986_RS13175	COG0347	Belongs to the P(II) protein family
PF986_RS13180	COG0772	Belongs to the SEDS family
PF986_RS13185	COG0671	phosphoesterase, PA-phosphatase related
PF986_RS13195	COG0739	heme binding
PF986_RS13200	COG1247	-acetyltransferase
PF986_RS13215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PF986_RS13225	COG0726	polysaccharide deacetylase
PF986_RS13230	COG1959	2 iron, 2 sulfur cluster binding
PF986_RS13245	COG0831	urea catabolic process
PF986_RS13255	COG1994	Peptidase M50
PF986_RS13260	COG0457	Tetratricopeptide repeat
PF986_RS13270	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PF986_RS13280	COG2304	oxidoreductase activity
PF986_RS13285	COG2304	oxidoreductase activity
PF986_RS13290	COG2385	sporulation resulting in formation of a cellular spore
PF986_RS13295	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PF986_RS13305	COG4836	Membrane
PF986_RS13375	COG0698	ribose 5-phosphate isomerase
PF986_RS13380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PF986_RS13390	COG0009	L-threonylcarbamoyladenylate synthase
PF986_RS13395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PF986_RS13415	COG2890	protein-(glutamine-N5) methyltransferase activity
PF986_RS13420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PF986_RS13425	COG0346	lactoylglutathione lyase activity
PF986_RS13430	COG0789	Transcriptional regulator
PF986_RS13435	COG0679	Auxin Efflux Carrier
PF986_RS13440	COG0281	malic enzyme
PF986_RS13455	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PF986_RS13465	COG1494	fructose-1,6-bisphosphatase
PF986_RS13470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PF986_RS13480	COG0191	fructose-bisphosphate aldolase activity
PF986_RS13485	COG2204	response regulator
PF986_RS13490	COG4821	SIS domain
PF986_RS13505	COG0247	lactate metabolic process
PF986_RS13505	COG2181	nitrate reductase activity
PF986_RS13510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PF986_RS13525	COG1132	(ABC) transporter
PF986_RS13530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PF986_RS13540	COG2181	nitrate reductase activity
PF986_RS13545	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PF986_RS13550	COG1140	nitrate reductase beta subunit
PF986_RS13555	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PF986_RS13560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PF986_RS13570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PF986_RS13575	COG2223	nitrite transmembrane transporter activity
PF986_RS13585	COG4506	Protein conserved in bacteria
PF986_RS13590	COG0457	Tetratricopeptide repeat
PF986_RS13630	COG0018	arginyl-trna synthetase
PF986_RS13635	COG0010	Belongs to the arginase family
PF986_RS13640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PF986_RS13645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PF986_RS13660	COG1994	Peptidase M50
PF986_RS13665	COG1942	4-Oxalocrotonate Tautomerase
PF986_RS13670	COG1846	Transcriptional regulator
PF986_RS13675	COG0531	amino acid
PF986_RS13680	COG3465	dGTPase activity
PF986_RS13685	COG1078	dGTPase activity
PF986_RS13700	COG1695	Transcriptional regulator
PF986_RS13710	COG1131	(ABC) transporter
PF986_RS13715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PF986_RS13745	COG0583	DNA-binding transcription factor activity
PF986_RS13755	COG0280	phosphate acetyltransferase
PF986_RS13765	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS13770	COG0436	Aminotransferase
PF986_RS13800	COG2814	Major facilitator Superfamily
PF986_RS13805	COG2814	Major facilitator Superfamily
PF986_RS13810	COG0833	amino acid
PF986_RS13815	COG4187	Peptidase family M20/M25/M40
PF986_RS13820	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS13825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PF986_RS13830	COG2205	protein histidine kinase activity
PF986_RS13835	COG0745	RESPONSE REGULATOR receiver
PF986_RS13850	COG1131	(ABC) transporter
PF986_RS13855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PF986_RS13860	COG1091	dTDP-4-dehydrorhamnose reductase activity
PF986_RS13865	COG1088	dTDP-glucose 4,6-dehydratase activity
PF986_RS13870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PF986_RS13875	COG3980	spore coat polysaccharide biosynthesis protein
PF986_RS13880	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
PF986_RS13885	COG2089	acid synthase
PF986_RS13890	COG0456	acetyltransferase
PF986_RS13895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PF986_RS13900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PF986_RS13905	COG0463	Glycosyl transferase, family 2
PF986_RS13915	COG2363	Small membrane protein
PF986_RS13920	COG2233	PERMEase
PF986_RS13935	COG1216	Glycosyl transferase, family 2
PF986_RS13950	COG1695	Transcriptional regulator
PF986_RS13955	COG0351	phosphomethylpyrimidine kinase
PF986_RS13965	COG1621	beta-fructofuranosidase activity
PF986_RS13970	COG1263	PTS System
PF986_RS13970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS13975	COG3711	transcriptional antiterminator
PF986_RS13985	COG1404	Belongs to the peptidase S8 family
PF986_RS13990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS13995	COG0778	Nitroreductase
PF986_RS14000	COG0772	Belongs to the SEDS family
PF986_RS14010	COG0454	-acetyltransferase
PF986_RS14030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PF986_RS14035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PF986_RS14040	COG2261	transglycosylase associated protein
PF986_RS14045	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PF986_RS14050	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PF986_RS14055	COG2246	polysaccharide biosynthetic process
PF986_RS14060	COG1309	transcriptional regulator
PF986_RS14080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PF986_RS14085	COG2837	iron assimilation
PF986_RS14090	COG2822	iron ion transport
PF986_RS14105	COG0583	DNA-binding transcription factor activity
PF986_RS14115	COG1346	cytolysis
PF986_RS14120	COG4895	conserved protein (DUF2196)
PF986_RS14130	COG5504	Zn-dependent protease
PF986_RS14135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PF986_RS14140	COG0346	lactoylglutathione lyase activity
PF986_RS14145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS14150	COG1404	Belongs to the peptidase S8 family
PF986_RS14155	COG1442	glycosyl transferase family 8
PF986_RS14160	COG1846	Transcriptional regulator
PF986_RS14165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PF986_RS14170	COG2357	RelA SpoT domain protein
PF986_RS14175	COG1575	Belongs to the MenA family. Type 1 subfamily
PF986_RS14190	COG1696	Membrane protein involved in D-alanine export
PF986_RS14200	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PF986_RS14205	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PF986_RS14210	COG1486	melibiose metabolic process
PF986_RS14215	COG1447	Phosphotransferase system cellobiose-specific component IIA
PF986_RS14220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS14225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS14230	COG3711	transcriptional antiterminator
PF986_RS14230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS14245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS14250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS14260	COG0640	Transcriptional regulator
PF986_RS14265	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PF986_RS14270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS14275	COG1447	Phosphotransferase system cellobiose-specific component IIA
PF986_RS14280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PF986_RS14285	COG2723	6-phospho-beta-galactosidase activity
PF986_RS14290	COG1940	carbohydrate kinase activity
PF986_RS14295	COG1482	cell wall glycoprotein biosynthetic process
PF986_RS14305	COG0753	catalase activity
PF986_RS14310	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
PF986_RS14315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PF986_RS14320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PF986_RS14325	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PF986_RS14330	COG4988	ABC transporter
PF986_RS14335	COG1294	oxidase, subunit
PF986_RS14340	COG1271	oxidase subunit
PF986_RS14345	COG3493	citrate carrier protein
PF986_RS14350	COG0726	polysaccharide deacetylase
PF986_RS14355	COG3842	ATPase activity
PF986_RS14360	COG2508	Transcriptional regulator
PF986_RS14365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS14375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PF986_RS14390	COG4894	glucomannan catabolic process
PF986_RS14395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PF986_RS14400	COG0500	methyltransferase
PF986_RS14405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PF986_RS14425	COG0693	protein deglycase activity
PF986_RS14425	COG0753	catalase activity
PF986_RS14430	COG2851	Citrate transporter
PF986_RS14435	COG2273	Hydrolase Family 16
PF986_RS14445	COG2270	Major facilitator Superfamily
PF986_RS14450	COG0513	Belongs to the DEAD box helicase family
PF986_RS14515	COG3209	COG3209 Rhs family protein
PF986_RS14525	COG0697	spore germination
PF986_RS14530	COG0589	response to stress
PF986_RS14535	COG2723	6-phospho-beta-galactosidase activity
PF986_RS14540	COG1263	PTS System
PF986_RS14540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS14540	COG2190	(PTS) system
PF986_RS14565	COG3507	Belongs to the glycosyl hydrolase 43 family
PF986_RS14590	COG0010	Belongs to the arginase family
PF986_RS14595	COG0833	amino acid
PF986_RS14600	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PF986_RS14605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PF986_RS14615	COG2390	Transcriptional regulator
PF986_RS14645	COG1131	(ABC) transporter
PF986_RS14655	COG0561	phosphatase activity
PF986_RS14685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PF986_RS14690	COG5294	Protein conserved in bacteria
PF986_RS14695	COG0577	efflux transmembrane transporter activity
PF986_RS14700	COG1136	(ABC) transporter
PF986_RS14705	COG2205	protein histidine kinase activity
PF986_RS14710	COG0745	RESPONSE REGULATOR receiver
PF986_RS14725	COG1082	Xylose isomerase domain protein TIM barrel
PF986_RS14735	COG2814	Major facilitator Superfamily
PF986_RS14765	COG1349	DNA-binding transcription factor activity
PF986_RS14770	COG0667	Aldo Keto reductase
PF986_RS14775	COG2814	Major facilitator Superfamily
PF986_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS14795	COG2197	response regulator
PF986_RS14800	COG4585	Histidine kinase
PF986_RS14805	COG3239	Fatty acid desaturase
PF986_RS14810	COG1309	transcriptional regulator
PF986_RS14820	COG1476	TRANSCRIPTIONal
PF986_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS14865	COG0640	Transcriptional regulator
PF986_RS14870	COG2814	Major facilitator Superfamily
PF986_RS14875	COG1714	RDD family
PF986_RS14885	COG0450	alkyl hydroperoxide reductase
PF986_RS14890	COG3634	alkyl hydroperoxide reductase activity
PF986_RS14895	COG3177	Filamentation induced by cAMP protein fic
PF986_RS14900	COG1113	amino acid transport
PF986_RS14910	COG2080	2 iron, 2 sulfur cluster binding
PF986_RS14925	COG2068	MobA-Related Protein
PF986_RS14930	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PF986_RS14950	COG1192	Involved in chromosome partitioning
PF986_RS14990	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PF986_RS14995	COG0667	Aldo Keto reductase
PF986_RS15000	COG0456	acetyltransferase
PF986_RS15010	COG0457	Tetratricopeptide repeat
PF986_RS15015	COG0010	Belongs to the arginase family
PF986_RS15020	COG0833	amino acid
PF986_RS15025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PF986_RS15030	COG5658	integral membrane protein
PF986_RS15035	COG0640	Transcriptional regulator
PF986_RS15040	COG3829	transcription factor binding
PF986_RS15050	COG0488	(ABC) transporter
PF986_RS15065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PF986_RS15070	COG3850	Histidine kinase
PF986_RS15070	COG5002	protein histidine kinase activity
PF986_RS15075	COG0745	RESPONSE REGULATOR receiver
PF986_RS15085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PF986_RS15090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PF986_RS15095	COG4853	Protein conserved in bacteria
PF986_RS15100	COG4863	YycH protein
PF986_RS15105	COG5002	protein histidine kinase activity
PF986_RS15110	COG0745	RESPONSE REGULATOR receiver
PF986_RS15140	COG0346	lactoylglutathione lyase activity
PF986_RS15145	COG0305	Participates in initiation and elongation during chromosome replication
PF986_RS15160	COG3093	addiction module antidote protein HigA
PF986_RS15165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PF986_RS15170	COG0297	glycogen (starch) synthase activity
PF986_RS15180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PF986_RS15185	COG0438	transferase activity, transferring glycosyl groups
PF986_RS15205	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PF986_RS15210	COG4241	membrane
PF986_RS15220	COG5577	PFAM Coat F domain
PF986_RS15225	COG1733	regulation of RNA biosynthetic process
PF986_RS15235	COG0697	spore germination
PF986_RS15240	COG1621	beta-fructofuranosidase activity
PF986_RS15245	COG1621	beta-fructofuranosidase activity
PF986_RS15255	COG2318	DinB family
PF986_RS15260	COG2211	Major facilitator Superfamily
PF986_RS15265	COG0697	spore germination
PF986_RS15275	COG0778	Nitroreductase
PF986_RS15280	COG1846	Transcriptional regulator
PF986_RS15285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS15290	COG1846	Transcriptional regulator
PF986_RS15295	COG2153	protein acetylation
PF986_RS15300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF986_RS15305	COG0697	spore germination
PF986_RS15315	COG4978	Transcriptional regulator
PF986_RS15315	COG0789	Transcriptional regulator
PF986_RS15320	COG1811	Na channel or pump
PF986_RS15330	COG1331	Highly conserved protein containing a thioredoxin domain
PF986_RS15335	COG1266	CAAX protease self-immunity
PF986_RS15340	COG2814	Major facilitator Superfamily
PF986_RS15340	COG0477	Major facilitator Superfamily
PF986_RS15345	COG0346	lactoylglutathione lyase activity
PF986_RS15350	COG1609	Transcriptional regulator
PF986_RS15355	COG0708	Exodeoxyribonuclease III
PF986_RS15360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PF986_RS15365	COG2169	Transcriptional regulator
PF986_RS15375	COG0629	single-stranded DNA binding
PF986_RS15385	COG0012	GTP binding
PF986_RS15390	COG0243	molybdopterin cofactor binding
PF986_RS15395	COG4481	Protein conserved in bacteria
PF986_RS15400	COG3949	Membrane
PF986_RS15415	COG1475	DNA binding
PF986_RS15420	COG1192	Involved in chromosome partitioning
PF986_RS15445	COG1847	R3H domain protein
PF986_RS15450	COG0706	membrane insertase activity
PF986_RS15470	COG0592	DNA-directed DNA polymerase activity
PF986_RS15475	COG2501	S4 domain
PF986_RS15490	COG0187	DNA topoisomerase II activity
PF986_RS15495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PF986_RS15530	COG0517	IMP dehydrogenase activity
PF986_RS15530	COG0516	GMP reductase activity
PF986_RS15535	COG1686	Belongs to the peptidase S11 family
PF986_RS15555	COG1929	Belongs to the glycerate kinase type-1 family
PF986_RS15565	COG1428	Deoxynucleoside kinase
PF986_RS15570	COG1428	Deoxynucleoside kinase
PF986_RS15575	COG3858	chitin binding
PF986_RS15575	COG1388	LysM domain
PF986_RS15580	COG1335	isochorismatase
PF986_RS15585	COG0590	tRNA wobble adenosine to inosine editing
PF986_RS15595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PF986_RS15600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PF986_RS15650	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PF986_RS15655	COG3853	Toxic anion resistance protein (TelA)
PF986_RS15660	COG1982	Orn Lys Arg decarboxylase major
PF986_RS15670	COG3870	Protein conserved in bacteria
PF986_RS15675	COG1728	Protein conserved in bacteria
PF986_RS15680	COG0470	DNA polymerase III
PF986_RS15685	COG1774	PSP1 C-terminal conserved region
PF986_RS15695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PF986_RS15705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PF986_RS15710	COG2002	toxin-antitoxin pair type II binding
PF986_RS15715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF986_RS15715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PF986_RS15720	COG0084	hydrolase, TatD family'
PF986_RS15725	COG3584	3D domain protein
PF986_RS15725	COG3583	domain protein
PF986_RS15730	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PF986_RS15735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PF986_RS15745	COG4466	Protein conserved in bacteria
PF986_RS15760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PF986_RS15765	COG0251	oxidation-reduction process
PF986_RS15780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PF986_RS15800	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PF986_RS15805	COG2002	toxin-antitoxin pair type II binding
PF986_RS15810	COG2244	polysaccharide biosynthetic process
PF986_RS15815	COG3956	TIGRFAM MazG family protein
PF986_RS15820	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PF986_RS15835	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PF986_RS15840	COG1098	S1 RNA binding domain
PF986_RS15855	COG2208	phosphoserine phosphatase activity
PF986_RS15860	COG2304	oxidoreductase activity
PF986_RS15865	COG0515	serine threonine protein kinase
PF986_RS15870	COG0037	tRNA processing
PF986_RS15875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PF986_RS15880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PF986_RS15895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PF986_RS15900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PF986_RS15905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PF986_RS15910	COG0512	Glutamine amidotransferase of anthranilate synthase
PF986_RS15915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PF986_RS15920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PF986_RS15925	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PF986_RS15930	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PF986_RS15935	COG1396	sequence-specific DNA binding
PF986_RS15940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PF986_RS15945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PF986_RS16025	COG4463	regulation of RNA biosynthetic process
PF986_RS16030	COG3880	PFAM UvrB UvrC protein
PF986_RS16040	COG0542	response to heat
PF986_RS16045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PF986_RS16050	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PF986_RS16055	COG4956	integral membrane protein (PIN domain superfamily)
PF986_RS16075	COG1045	serine acetyltransferase
PF986_RS16085	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PF986_RS16090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PF986_RS16095	COG3688	RNA-binding protein containing a PIN domain
PF986_RS16100	COG1595	DNA-templated transcription, initiation
PF986_RS16110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PF986_RS16115	COG0250	Participates in transcription elongation, termination and antitermination
PF986_RS16140	COG2813	Specifically methylates the guanine in position
PF986_RS16155	COG1358	cellular component organization or biogenesis
PF986_RS16180	COG0596	Alpha beta hydrolase
PF986_RS16290	COG0201	protein transport
PF986_RS16300	COG0024	Methionine aminopeptidase
PF986_RS16315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PF986_RS16340	COG1122	ATPase activity
PF986_RS16345	COG1122	ATPase activity
PF986_RS16350	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PF986_RS16370	COG2226	methyltransferase
PF986_RS16375	COG2318	DinB family
PF986_RS16385	COG0860	N-Acetylmuramoyl-L-alanine amidase
PF986_RS16390	COG0489	protein tyrosine kinase activity
PF986_RS16400	COG2194	sulfuric ester hydrolase activity
PF986_RS16405	COG0726	polysaccharide deacetylase
PF986_RS16470	COG0738	Major facilitator superfamily
PF986_RS16475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PF986_RS16485	COG1063	alcohol dehydrogenase
PF986_RS16490	COG0659	secondary active sulfate transmembrane transporter activity
PF986_RS16495	COG0385	Bile acid
PF986_RS16500	COG2819	hydrolase of the alpha beta superfamily
PF986_RS16505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS16510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS16515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PF986_RS16520	COG2207	Transcriptional regulator
PF986_RS16520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PF986_RS16525	COG3876	Protein conserved in bacteria
PF986_RS16530	COG1472	Belongs to the glycosyl hydrolase 3 family
PF986_RS16535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF986_RS16540	COG1263	PTS System
PF986_RS16540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS16550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PF986_RS16555	COG1683	Conserved Protein
PF986_RS16585	COG1595	DNA-templated transcription, initiation
PF986_RS16590	COG5662	AntiSigma factor
PF986_RS16595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PF986_RS16600	COG4856	YbbR-like protein
PF986_RS16640	COG1063	alcohol dehydrogenase
PF986_RS16650	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS16685	COG1346	cytolysis
PF986_RS16690	COG1380	Effector of murein hydrolase LrgA
PF986_RS16695	COG1846	Transcriptional regulator
PF986_RS16700	COG1113	amino acid transport
PF986_RS16705	COG1011	Hydrolase
PF986_RS16710	COG4585	Histidine kinase
PF986_RS16715	COG2197	response regulator
PF986_RS16720	COG1131	(ABC) transporter
PF986_RS16760	COG0531	amino acid
PF986_RS16785	COG0584	glycerophosphoryl diester phosphodiesterase
PF986_RS16790	COG2271	Major facilitator Superfamily
PF986_RS16800	COG2368	4-hydroxyphenylacetate
PF986_RS16810	COG3409	Peptidoglycan-binding domain 1 protein
PF986_RS16825	COG0371	Dehydrogenase
PF986_RS16835	COG1183	phosphatidylcholine synthase activity
PF986_RS16840	COG0586	Pfam SNARE associated Golgi protein
PF986_RS16845	COG0688	phosphatidylethanolamine metabolic process
PF986_RS16860	COG1301	dicarboxylic acid transport
PF986_RS16865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PF986_RS16870	COG0833	amino acid
PF986_RS16875	COG2040	homocysteine
PF986_RS16880	COG1115	amino acid carrier protein
PF986_RS16885	COG2066	Belongs to the glutaminase family
PF986_RS16890	COG4191	Histidine kinase
PF986_RS16895	COG0784	Response regulator, receiver
PF986_RS16900	COG3173	Aminoglycoside phosphotransferase
PF986_RS16915	COG3773	Cell wall hydrolase
PF986_RS16920	COG3540	Alkaline phosphatase
PF986_RS16925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PF986_RS16930	COG0805	protein transport
PF986_RS16940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PF986_RS16945	COG0477	Major facilitator Superfamily
PF986_RS16950	COG1309	transcriptional regulator
PF986_RS16955	COG0252	asparaginase activity
PF986_RS16960	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PF986_RS16965	COG1405	negative regulation of cell septum assembly
PF986_RS16965	COG3012	SEC-C Motif Domain Protein
PF986_RS16970	COG0667	Aldo Keto reductase
PF986_RS16980	COG1595	DNA-templated transcription, initiation
PF986_RS16985	COG1595	DNA-templated transcription, initiation
PF986_RS16990	COG1876	peptidase activity
PF986_RS16995	COG0457	Tetratricopeptide repeat
PF986_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS17010	COG0366	Alpha amylase catalytic
PF986_RS17015	COG0803	Belongs to the bacterial solute-binding protein 9 family
PF986_RS17020	COG1121	(ABC) transporter
PF986_RS17025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PF986_RS17030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS17035	COG2310	stress, protein
PF986_RS17040	COG2310	stress, protein
PF986_RS17045	COG2310	stress, protein
PF986_RS17050	COG0861	Integral membrane protein TerC family
PF986_RS17060	COG3853	Toxic anion resistance protein (TelA)
PF986_RS17065	COG0477	Major facilitator Superfamily
PF986_RS17070	COG4175	Glycine betaine
PF986_RS17070	COG0517	IMP dehydrogenase activity
PF986_RS17075	COG4176	ABC-type proline glycine betaine transport system permease component
PF986_RS17080	COG2113	Glycine betaine
PF986_RS17085	COG1473	amidohydrolase
PF986_RS17090	COG1288	antiporter activity
PF986_RS17100	COG0366	Alpha amylase catalytic
PF986_RS17165	COG2814	Major facilitator Superfamily
PF986_RS17170	COG1846	Transcriptional regulator
PF986_RS17175	COG1280	lysine exporter protein (LysE YggA)
PF986_RS17180	COG3403	YqcI/YcgG family
PF986_RS17185	COG1113	amino acid transport
PF986_RS17190	COG3665	Urea carboxylase-associated protein
PF986_RS17205	COG1660	Displays ATPase and GTPase activities
PF986_RS17215	COG2271	Major facilitator Superfamily
PF986_RS17220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PF986_RS17225	COG3458	cephalosporin-C deacetylase activity
PF986_RS17235	COG0506	proline dehydrogenase activity
PF986_RS17240	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS17245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF986_RS17250	COG2508	Transcriptional regulator
PF986_RS17260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PF986_RS17260	COG1587	Uroporphyrinogen-III synthase
PF986_RS17265	COG2146	nitrite reductase [NAD(P)H] activity
PF986_RS17270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PF986_RS17280	COG0523	cobalamin synthesis protein
PF986_RS17285	COG1063	alcohol dehydrogenase
PF986_RS17290	COG1714	RDD family
PF986_RS17300	COG2723	6-phospho-beta-galactosidase activity
PF986_RS17310	COG3209	COG3209 Rhs family protein
PF986_RS17315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PF986_RS17320	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
PF986_RS17325	COG1733	regulation of RNA biosynthetic process
PF986_RS17330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS17345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS17350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PF986_RS17355	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PF986_RS17370	COG2364	Membrane
PF986_RS17375	COG1126	abc transporter atp-binding protein
PF986_RS17380	COG0765	amino acid transport
PF986_RS17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS17390	COG0583	DNA-binding transcription factor activity
PF986_RS17395	COG0163	prenyltransferase activity
PF986_RS17400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PF986_RS17415	COG3104	oligopeptide transport
PF986_RS17420	COG5434	Belongs to the glycosyl hydrolase 28 family
PF986_RS17430	COG0697	spore germination
PF986_RS17440	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PF986_RS17445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PF986_RS17450	COG0456	acetyltransferase
PF986_RS17455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PF986_RS17460	COG0765	amino acid transport
PF986_RS17465	COG1126	abc transporter atp-binding protein
PF986_RS17470	COG1473	amidohydrolase
PF986_RS17475	COG2079	MmgE PrpD family protein
PF986_RS17480	COG1136	(ABC) transporter
PF986_RS17485	COG0577	efflux transmembrane transporter activity
PF986_RS17490	COG0745	RESPONSE REGULATOR receiver
PF986_RS17495	COG3850	Histidine kinase
PF986_RS17495	COG5002	protein histidine kinase activity
PF986_RS17500	COG0457	Tetratricopeptide repeat
PF986_RS17515	COG0527	aspartate kinase activity
PF986_RS17520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PF986_RS17525	COG4605	iron ion homeostasis
PF986_RS17530	COG4604	ABC transporter, ATP-binding protein
PF986_RS17535	COG4607	ABC-type enterochelin transport system periplasmic component
PF986_RS17540	COG2814	Major facilitator Superfamily
PF986_RS17545	COG1309	transcriptional regulator
PF986_RS17550	COG0778	Nitroreductase
PF986_RS17555	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PF986_RS17560	COG0640	Transcriptional regulator
PF986_RS17565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF986_RS17570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PF986_RS17575	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS17580	COG4975	Glucose uptake
PF986_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS17590	COG4549	nuclear export factor GLE1
PF986_RS17595	COG1276	copper resistance
PF986_RS17595	COG2372	response to copper ion
PF986_RS17600	COG1349	DNA-binding transcription factor activity
PF986_RS17610	COG2213	PTS system mannitol-specific
PF986_RS17615	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PF986_RS17625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PF986_RS17635	COG0561	phosphatase activity
PF986_RS17645	COG1914	H( )-stimulated, divalent metal cation uptake system
PF986_RS17655	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PF986_RS17660	COG1984	allophanate hydrolase subunit 2
PF986_RS17665	COG1414	Transcriptional regulator
PF986_RS17670	COG2755	lipolytic protein G-D-S-L family
PF986_RS17680	COG2329	Antibiotic biosynthesis monooxygenase
PF986_RS17685	COG0768	penicillin binding
PF986_RS17690	COG4989	oxidoreductase activity
PF986_RS17695	COG3711	transcriptional antiterminator
PF986_RS17700	COG0318	PFAM AMP-dependent synthetase and ligase
PF986_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS17710	COG1917	Cupin 2, conserved barrel domain protein
PF986_RS17715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PF986_RS17720	COG3871	stress protein (general stress protein 26)
PF986_RS17735	COG2814	Major facilitator Superfamily
PF986_RS17740	COG1522	sequence-specific DNA binding
PF986_RS17745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PF986_RS17745	COG0551	DNA topoisomerase type I activity
PF986_RS17750	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PF986_RS17755	COG3706	GGDEF domain
PF986_RS17760	COG5298	Protein conserved in bacteria
PF986_RS17765	COG1215	transferase activity, transferring glycosyl groups
PF986_RS17780	COG0531	amino acid
PF986_RS17785	COG0494	nUDIX hydrolase
PF986_RS17790	COG0028	Belongs to the TPP enzyme family
PF986_RS17815	COG1914	H( )-stimulated, divalent metal cation uptake system
PF986_RS17835	COG2076	Multidrug Resistance protein
PF986_RS17840	COG2217	Heavy metal translocating P-type atpase
PF986_RS17845	COG3729	General stress protein
PF986_RS17850	COG0662	Cupin 2, conserved barrel domain protein
PF986_RS17855	COG2329	Antibiotic biosynthesis monooxygenase
PF986_RS17860	COG3546	catalase activity
PF986_RS17865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PF986_RS17870	COG3290	protein histidine kinase activity
PF986_RS17875	COG4565	transcriptional regulatory protein
PF986_RS17880	COG1301	dicarboxylic acid transport
PF986_RS17885	COG0628	permease
PF986_RS17890	COG1131	(ABC) transporter
PF986_RS17895	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PF986_RS17905	COG1960	acyl-CoA dehydrogenase activity
PF986_RS17920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PF986_RS17925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PF986_RS17935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PF986_RS17940	COG0513	Belongs to the DEAD box helicase family
PF986_RS17945	COG3402	PFAM membrane-flanked domain
PF986_RS17950	COG3428	Bacterial PH domain
PF986_RS17955	COG0705	Rhomboid family
PF986_RS17965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PF986_RS17970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PF986_RS17975	COG0864	Transcriptional regulator
PF986_RS17980	COG2337	Toxic component of a toxin-antitoxin (TA) module
PF986_RS17985	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS17990	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS17995	COG2172	sigma factor antagonist activity
PF986_RS18000	COG2208	phosphoserine phosphatase activity
PF986_RS18005	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS18015	COG1191	sigma factor activity
PF986_RS18020	COG2208	phosphoserine phosphatase activity
PF986_RS18025	COG2183	response to ionizing radiation
PF986_RS18080	COG5444	nuclease activity
PF986_RS18095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PF986_RS18100	COG0477	Major facilitator Superfamily
PF986_RS18115	COG2030	dehydratase
PF986_RS18130	COG1959	2 iron, 2 sulfur cluster binding
PF986_RS18135	COG2910	NAD(P)H-binding
PF986_RS18140	COG1278	Cold shock
PF986_RS18145	COG1329	Transcriptional regulator
PF986_RS18150	COG1794	racemase activity, acting on amino acids and derivatives
PF986_RS18165	COG3621	Patatin-like phospholipase
PF986_RS18175	COG0662	Cupin 2, conserved barrel domain protein
PF986_RS18190	COG0277	FAD linked oxidase domain protein
PF986_RS18215	COG0662	Cupin 2, conserved barrel domain protein
PF986_RS18220	COG2318	DinB family
PF986_RS18225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PF986_RS18250	COG1064	alcohol dehydrogenase
PF986_RS18255	COG0789	Transcriptional regulator
PF986_RS18265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PF986_RS18280	COG2814	Major facilitator Superfamily
PF986_RS18285	COG1309	transcriptional regulator
PF986_RS18290	COG5577	PFAM Coat F domain
PF986_RS18300	COG1063	alcohol dehydrogenase
PF986_RS18305	COG5577	PFAM Coat F domain
PF986_RS18315	COG4585	Histidine kinase
PF986_RS18320	COG2197	response regulator
PF986_RS18325	COG2409	Drug exporters of the RND superfamily
PF986_RS18330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PF986_RS18335	COG0488	(ABC) transporter
PF986_RS18340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PF986_RS18345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PF986_RS18355	COG2814	Major facilitator Superfamily
PF986_RS18360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PF986_RS18370	COG0730	response to heat
PF986_RS18375	COG0456	acetyltransferase
PF986_RS18380	COG0789	Transcriptional regulator
PF986_RS18380	COG4978	Transcriptional regulator
PF986_RS18385	COG0697	spore germination
PF986_RS18390	COG1051	belongs to the nudix hydrolase family
PF986_RS18395	COG2226	methyltransferase
PF986_RS18400	COG0473	3-isopropylmalate dehydrogenase activity
PF986_RS18405	COG1802	Transcriptional regulator
PF986_RS18410	COG1819	glycosyl
PF986_RS18425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PF986_RS18435	COG1388	LysM domain
PF986_RS18440	COG2814	Major facilitator Superfamily
PF986_RS18445	COG2188	Transcriptional regulator
PF986_RS18450	COG2186	Transcriptional regulator
PF986_RS18455	COG2807	transmembrane transport
PF986_RS18460	COG2076	Multidrug Resistance protein
PF986_RS18465	COG2076	Multidrug Resistance protein
PF986_RS18470	COG1309	transcriptional regulator
PF986_RS18475	COG0531	amino acid
PF986_RS18485	COG3832	glyoxalase III activity
PF986_RS18490	COG0604	alcohol dehydrogenase
PF986_RS18495	COG2814	Major facilitator Superfamily
PF986_RS18535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PF986_RS18540	COG0802	atpase or kinase
PF986_RS18545	COG1214	PFAM Peptidase M22, glycoprotease
PF986_RS18550	COG0456	acetyltransferase
PF986_RS18555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PF986_RS18560	COG0488	(ABC) transporter
PF986_RS18575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PF986_RS18580	COG0805	protein transport
PF986_RS18590	COG1266	CAAX protease self-immunity
PF986_RS18605	COG0156	8-amino-7-oxononanoate synthase activity
PF986_RS18625	COG3403	YqcI/YcgG family
PF986_RS18640	COG2814	Major facilitator Superfamily
PF986_RS18645	COG0457	Tetratricopeptide repeat
PF986_RS18650	COG1063	alcohol dehydrogenase
PF986_RS18655	COG2211	Major facilitator Superfamily
PF986_RS18660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PF986_RS18670	COG1842	Phage shock protein A
PF986_RS18675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PF986_RS18680	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PF986_RS18685	COG4260	virion core protein, lumpy skin disease virus
PF986_RS18690	COG2755	lipolytic protein G-D-S-L family
PF986_RS18690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PF986_RS18700	COG1595	DNA-templated transcription, initiation
PF986_RS18705	COG1063	alcohol dehydrogenase
PF986_RS18710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PF986_RS18715	COG0823	Involved in the tonB-independent uptake of proteins
PF986_RS18730	COG2132	Multicopper oxidase
PF986_RS18735	COG1113	amino acid transport
PF986_RS18740	COG0714	Associated with various cellular activities
PF986_RS18745	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
PF986_RS18750	COG1305	Transglutaminase-like
PF986_RS18760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PF986_RS18775	COG2211	Major facilitator Superfamily
PF986_RS18790	COG2252	PERMEase
PF986_RS18795	COG3064	Membrane
PF986_RS18815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PF986_RS18820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PF986_RS18825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PF986_RS18830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PF986_RS18835	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PF986_RS18850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PF986_RS18860	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PF986_RS18865	COG0138	bifunctional purine biosynthesis protein purh
PF986_RS18870	COG0151	Belongs to the GarS family
PF986_RS18880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PF986_RS18885	COG1470	cell adhesion involved in biofilm formation
PF986_RS18890	COG4496	protein, YerC YecD
PF986_RS18895	COG0069	glutamate synthase activity
PF986_RS18905	COG0210	DNA helicase
PF986_RS18915	COG4851	CamS sex pheromone cAM373 precursor
PF986_RS18920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PF986_RS18925	COG1285	pathogenesis
PF986_RS18930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PF986_RS18950	COG1309	transcriptional regulator
PF986_RS18955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PF986_RS18960	COG1597	lipid kinase activity
PF986_RS18965	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PF986_RS18970	COG1136	(ABC) transporter
PF986_RS18980	COG1131	(ABC) transporter
PF986_RS19025	COG5444	nuclease activity
PF986_RS19035	COG5444	nuclease activity
PF986_RS19065	COG3546	catalase activity
PF986_RS19080	COG2323	membrane
PF986_RS19085	COG2329	Antibiotic biosynthesis monooxygenase
PF986_RS19090	COG0346	lactoylglutathione lyase activity
PF986_RS19095	COG1366	Belongs to the anti-sigma-factor antagonist family
PF986_RS19100	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PF986_RS19105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
PF986_RS19110	COG4208	sulfate ABC transporter
PF986_RS19120	COG5583	Uncharacterized small protein (DUF2292)
PF986_RS19125	COG0196	riboflavin kinase activity
PF986_RS19130	COG0670	Belongs to the BI1 family
PF986_RS19135	COG1846	Transcriptional regulator
PF986_RS19140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PF986_RS19150	COG2124	cytochrome p450
PF986_RS19150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PF986_RS19165	COG1131	(ABC) transporter
PF986_RS19175	COG1368	sulfuric ester hydrolase activity
PF986_RS19180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PF986_RS19185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PF986_RS19190	COG1442	glycosyl transferase family 8
PF986_RS19200	COG1442	glycosyl transferase family 8
PF986_RS19205	COG2223	nitrite transmembrane transporter activity
PF986_RS19210	COG0531	amino acid
PF986_RS19215	COG1012	belongs to the aldehyde dehydrogenase family
PF986_RS19220	COG0840	transmembrane signaling receptor activity
PF986_RS19225	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS19230	COG0463	Glycosyl transferase, family 2
PF986_RS19230	COG0457	Tetratricopeptide repeat
PF986_RS19235	COG0488	(ABC) transporter
PF986_RS19240	COG0789	Transcriptional regulator
PF986_RS19245	COG2814	Major facilitator Superfamily
PF986_RS19250	COG0488	(ABC) transporter
PF986_RS19255	COG0513	Belongs to the DEAD box helicase family
PF986_RS19265	COG2130	NADP-dependent
PF986_RS19280	COG3866	Pectate lyase
PF986_RS19285	COG0471	metal ion transport
PF986_RS19310	COG3290	protein histidine kinase activity
PF986_RS19315	COG4565	transcriptional regulatory protein
PF986_RS19320	COG3181	Tripartite tricarboxylate transporter family receptor
PF986_RS19325	COG2851	Citrate transporter
PF986_RS19330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PF986_RS19335	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PF986_RS19345	COG2258	MOSC domain
PF986_RS19365	COG0024	Methionine aminopeptidase
PF986_RS19370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS19370	COG1263	PTS System
PF986_RS19380	COG1368	sulfuric ester hydrolase activity
PF986_RS19390	COG0071	Belongs to the small heat shock protein (HSP20) family
PF986_RS19405	COG1263	PTS System
PF986_RS19405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS19410	COG0366	Alpha amylase catalytic
PF986_RS19415	COG2188	Transcriptional regulator
PF986_RS19420	COG0778	Nitroreductase
PF986_RS19435	COG0737	Belongs to the 5'-nucleotidase family
PF986_RS19440	COG0693	protein deglycase activity
PF986_RS19445	COG1609	Transcriptional regulator
PF986_RS19460	COG2814	Major facilitator Superfamily
PF986_RS19470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PF986_RS19475	COG4980	gas vesicle protein
PF986_RS19480	COG1295	ribonuclease BN
PF986_RS19490	COG0477	Major facilitator Superfamily
PF986_RS19495	COG0387	Pfam Sodium calcium exchanger
PF986_RS19505	COG0668	transmembrane transport
PF986_RS19510	COG0535	radical SAM domain protein
PF986_RS19520	COG0726	polysaccharide deacetylase
PF986_RS19525	COG2084	Dehydrogenase
PF986_RS19535	COG0598	Magnesium transport protein CorA
PF986_RS19540	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PF986_RS19545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PF986_RS19555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PF986_RS19560	COG4637	Psort location Cytoplasmic, score
PF986_RS19565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PF986_RS19570	COG0022	dehydrogenase e1 component
PF986_RS19575	COG0508	dehydrogenase complex catalyzes the overall conversion of
PF986_RS19580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PF986_RS19585	COG3284	Transcriptional regulator
PF986_RS19595	COG1486	melibiose metabolic process
PF986_RS19600	COG1737	Transcriptional regulator
PF986_RS19605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PF986_RS19605	COG1263	PTS System
PF986_RS19610	COG1132	(ABC) transporter
PF986_RS19615	COG1132	(ABC) transporter
PF986_RS19620	COG2259	Doxx family
PF986_RS19625	COG2514	catechol 2,3-dioxygenase activity
PF986_RS19635	COG1695	Transcriptional regulator
PF986_RS19640	COG2249	NAD(P)H dehydrogenase (quinone) activity
PF986_RS19645	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PF986_RS19650	COG3848	Pyruvate phosphate dikinase
PF986_RS19650	COG0574	Belongs to the PEP-utilizing enzyme family
PF986_RS19655	COG2732	(Barnase) inhibitor
PF986_RS19660	COG2318	DinB family
PF986_RS19665	COG2814	Major facilitator Superfamily
PF986_RS19670	COG1846	Transcriptional regulator
PF986_RS19675	COG0392	lysyltransferase activity
PF986_RS19675	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PF986_RS19680	COG0384	phenazine biosynthesis protein PhzF
PF986_RS19685	COG0778	Nitroreductase
PF986_RS19700	COG1090	epimerase
PF986_RS19715	COG2814	Major facilitator Superfamily
PF986_RS19725	COG3591	Belongs to the peptidase S1B family
PF986_RS19740	COG3103	Sh3 type 3 domain protein
PF986_RS19745	COG5658	integral membrane protein
PF986_RS19750	COG0596	Alpha beta hydrolase
PF986_RS19755	COG0463	Glycosyl transferase, family 2
PF986_RS19760	COG4485	Bacterial membrane protein, YfhO
PF986_RS19765	COG1988	membrane-bound metal-dependent
PF986_RS19770	COG1194	a g-specific adenine glycosylase
PF986_RS19780	COG1028	Short-chain dehydrogenase reductase Sdr
PF986_RS19805	COG1132	(ABC) transporter
PF986_RS19810	COG4129	membrane
PF986_RS19820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PF986_RS19825	COG0735	belongs to the Fur family
PF986_RS19965	COG5577	PFAM Coat F domain
PF986_RS19970	COG3340	Belongs to the peptidase S51 family
PF986_RS19980	COG0277	FAD linked oxidase domain protein
PF986_RS19990	COG0747	negative chemotaxis
PF986_RS19995	COG0601	transmembrane transport
PF986_RS20000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PF986_RS20005	COG0444	Belongs to the ABC transporter superfamily
PF986_RS20010	COG4608	Belongs to the ABC transporter superfamily
PF986_RS20015	COG0753	catalase activity
PF986_RS20025	COG1116	anion transmembrane transporter activity
PF986_RS20030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PF986_RS20035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PF986_RS20060	COG1476	TRANSCRIPTIONal
PF986_RS20070	COG3382	B3 4 domain protein