locus-tag	class	description
F0M21_RS00010	COG0592	DNA-directed DNA polymerase activity
F0M21_RS00015	COG2501	S4 domain
F0M21_RS00030	COG0187	DNA topoisomerase II activity
F0M21_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F0M21_RS00070	COG0516	GMP reductase activity
F0M21_RS00070	COG0517	IMP dehydrogenase activity
F0M21_RS00075	COG1686	Belongs to the peptidase S11 family
F0M21_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
F0M21_RS00105	COG1428	Deoxynucleoside kinase
F0M21_RS00110	COG1428	Deoxynucleoside kinase
F0M21_RS00115	COG1388	LysM domain
F0M21_RS00115	COG3858	chitin binding
F0M21_RS00120	COG1335	isochorismatase
F0M21_RS00125	COG0590	tRNA wobble adenosine to inosine editing
F0M21_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F0M21_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F0M21_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
F0M21_RS00195	COG3853	Toxic anion resistance protein (TelA)
F0M21_RS00200	COG1982	Orn Lys Arg decarboxylase major
F0M21_RS00210	COG3870	Protein conserved in bacteria
F0M21_RS00215	COG1728	Protein conserved in bacteria
F0M21_RS00220	COG0470	DNA polymerase III
F0M21_RS00225	COG1774	PSP1 C-terminal conserved region
F0M21_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F0M21_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F0M21_RS00250	COG2002	toxin-antitoxin pair type II binding
F0M21_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M21_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M21_RS00260	COG0084	hydrolase, TatD family'
F0M21_RS00265	COG3583	domain protein
F0M21_RS00265	COG3584	3D domain protein
F0M21_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
F0M21_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F0M21_RS00285	COG4466	Protein conserved in bacteria
F0M21_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0M21_RS00305	COG0251	oxidation-reduction process
F0M21_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0M21_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0M21_RS00345	COG2002	toxin-antitoxin pair type II binding
F0M21_RS00350	COG2244	polysaccharide biosynthetic process
F0M21_RS00355	COG3956	TIGRFAM MazG family protein
F0M21_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F0M21_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F0M21_RS00380	COG1098	S1 RNA binding domain
F0M21_RS00395	COG2208	phosphoserine phosphatase activity
F0M21_RS00400	COG2304	oxidoreductase activity
F0M21_RS00405	COG0515	serine threonine protein kinase
F0M21_RS00410	COG0037	tRNA processing
F0M21_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F0M21_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0M21_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0M21_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0M21_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F0M21_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
F0M21_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F0M21_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F0M21_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0M21_RS00475	COG1396	sequence-specific DNA binding
F0M21_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0M21_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0M21_RS00565	COG4463	regulation of RNA biosynthetic process
F0M21_RS00570	COG3880	PFAM UvrB UvrC protein
F0M21_RS00580	COG0542	response to heat
F0M21_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
F0M21_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
F0M21_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
F0M21_RS00615	COG1045	serine acetyltransferase
F0M21_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
F0M21_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0M21_RS00635	COG3688	RNA-binding protein containing a PIN domain
F0M21_RS00640	COG1595	DNA-templated transcription, initiation
F0M21_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0M21_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
F0M21_RS00680	COG2813	Specifically methylates the guanine in position
F0M21_RS00695	COG1358	cellular component organization or biogenesis
F0M21_RS00720	COG0596	Alpha beta hydrolase
F0M21_RS00830	COG0201	protein transport
F0M21_RS00840	COG0024	Methionine aminopeptidase
F0M21_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0M21_RS00880	COG1122	ATPase activity
F0M21_RS00885	COG1122	ATPase activity
F0M21_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F0M21_RS00910	COG2226	methyltransferase
F0M21_RS00915	COG2318	DinB family
F0M21_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS00930	COG0489	protein tyrosine kinase activity
F0M21_RS00940	COG2194	sulfuric ester hydrolase activity
F0M21_RS00945	COG0726	polysaccharide deacetylase
F0M21_RS01005	COG0738	Major facilitator superfamily
F0M21_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
F0M21_RS01030	COG0385	Bile acid
F0M21_RS01035	COG2819	hydrolase of the alpha beta superfamily
F0M21_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0M21_RS01055	COG2207	Transcriptional regulator
F0M21_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0M21_RS01060	COG3876	Protein conserved in bacteria
F0M21_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
F0M21_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0M21_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS01075	COG1263	PTS System
F0M21_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M21_RS01090	COG1683	Conserved Protein
F0M21_RS01120	COG1595	DNA-templated transcription, initiation
F0M21_RS01125	COG5662	AntiSigma factor
F0M21_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F0M21_RS01135	COG4856	YbbR-like protein
F0M21_RS01175	COG2205	protein histidine kinase activity
F0M21_RS01185	COG1136	(ABC) transporter
F0M21_RS01190	COG0577	efflux transmembrane transporter activity
F0M21_RS01210	COG1346	cytolysis
F0M21_RS01215	COG1380	Effector of murein hydrolase LrgA
F0M21_RS01220	COG1846	Transcriptional regulator
F0M21_RS01225	COG1113	amino acid transport
F0M21_RS01230	COG1011	Hydrolase
F0M21_RS01235	COG4585	Histidine kinase
F0M21_RS01240	COG2197	response regulator
F0M21_RS01245	COG1131	(ABC) transporter
F0M21_RS01285	COG0531	amino acid
F0M21_RS01300	COG0584	glycerophosphoryl diester phosphodiesterase
F0M21_RS01305	COG2271	Major facilitator Superfamily
F0M21_RS01320	COG2368	4-hydroxyphenylacetate
F0M21_RS01330	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS01345	COG0371	Dehydrogenase
F0M21_RS01355	COG1183	phosphatidylcholine synthase activity
F0M21_RS01360	COG0586	Pfam SNARE associated Golgi protein
F0M21_RS01365	COG0688	phosphatidylethanolamine metabolic process
F0M21_RS01380	COG1301	dicarboxylic acid transport
F0M21_RS01385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS01390	COG0833	amino acid
F0M21_RS01395	COG2040	homocysteine
F0M21_RS01400	COG1115	amino acid carrier protein
F0M21_RS01405	COG2066	Belongs to the glutaminase family
F0M21_RS01410	COG4191	Histidine kinase
F0M21_RS01415	COG0784	Response regulator, receiver
F0M21_RS01420	COG3173	Aminoglycoside phosphotransferase
F0M21_RS01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0M21_RS01440	COG0778	Nitroreductase
F0M21_RS01445	COG0346	lactoylglutathione lyase activity
F0M21_RS01450	COG2259	Doxx family
F0M21_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS01470	COG3773	Cell wall hydrolase
F0M21_RS01480	COG3540	Alkaline phosphatase
F0M21_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0M21_RS01490	COG0805	protein transport
F0M21_RS01500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0M21_RS01505	COG0477	Major facilitator Superfamily
F0M21_RS01510	COG1309	transcriptional regulator
F0M21_RS01515	COG0252	asparaginase activity
F0M21_RS01520	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
F0M21_RS01525	COG1405	negative regulation of cell septum assembly
F0M21_RS01525	COG3012	SEC-C Motif Domain Protein
F0M21_RS01530	COG0667	Aldo Keto reductase
F0M21_RS01540	COG1595	DNA-templated transcription, initiation
F0M21_RS01545	COG1595	DNA-templated transcription, initiation
F0M21_RS01550	COG1876	peptidase activity
F0M21_RS01555	COG0457	Tetratricopeptide repeat
F0M21_RS01560	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS01565	COG0366	Alpha amylase catalytic
F0M21_RS01570	COG0803	Belongs to the bacterial solute-binding protein 9 family
F0M21_RS01575	COG1121	(ABC) transporter
F0M21_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0M21_RS01585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS01590	COG2310	stress, protein
F0M21_RS01595	COG2310	stress, protein
F0M21_RS01600	COG2310	stress, protein
F0M21_RS01605	COG0861	Integral membrane protein TerC family
F0M21_RS01615	COG3853	Toxic anion resistance protein (TelA)
F0M21_RS01620	COG0477	Major facilitator Superfamily
F0M21_RS01625	COG0517	IMP dehydrogenase activity
F0M21_RS01625	COG4175	Glycine betaine
F0M21_RS01630	COG4176	ABC-type proline glycine betaine transport system permease component
F0M21_RS01635	COG2113	Glycine betaine
F0M21_RS01640	COG1473	amidohydrolase
F0M21_RS01645	COG1288	antiporter activity
F0M21_RS01655	COG0366	Alpha amylase catalytic
F0M21_RS01665	COG2814	Major facilitator Superfamily
F0M21_RS01670	COG1846	Transcriptional regulator
F0M21_RS01675	COG1280	lysine exporter protein (LysE YggA)
F0M21_RS01680	COG3403	YqcI/YcgG family
F0M21_RS01685	COG1113	amino acid transport
F0M21_RS01690	COG3665	Urea carboxylase-associated protein
F0M21_RS01705	COG1660	Displays ATPase and GTPase activities
F0M21_RS01710	COG1082	Xylose isomerase domain protein TIM barrel
F0M21_RS01715	COG2271	Major facilitator Superfamily
F0M21_RS01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0M21_RS01725	COG3458	cephalosporin-C deacetylase activity
F0M21_RS01730	COG3541	Predicted nucleotidyltransferase
F0M21_RS01735	COG0506	proline dehydrogenase activity
F0M21_RS01740	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS01745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M21_RS01750	COG2508	Transcriptional regulator
F0M21_RS01760	COG1587	Uroporphyrinogen-III synthase
F0M21_RS01760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0M21_RS01765	COG2146	nitrite reductase [NAD(P)H] activity
F0M21_RS01770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0M21_RS01775	COG0243	molybdopterin cofactor binding
F0M21_RS01780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0M21_RS01785	COG2223	nitrite transmembrane transporter activity
F0M21_RS01790	COG0523	cobalamin synthesis protein
F0M21_RS01795	COG1063	alcohol dehydrogenase
F0M21_RS01800	COG1714	RDD family
F0M21_RS01810	COG2723	6-phospho-beta-galactosidase activity
F0M21_RS01820	COG3209	COG3209 Rhs family protein
F0M21_RS01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F0M21_RS01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
F0M21_RS01835	COG1733	regulation of RNA biosynthetic process
F0M21_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS01855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F0M21_RS01870	COG0697	spore germination
F0M21_RS01875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M21_RS01885	COG2364	Membrane
F0M21_RS01890	COG1126	abc transporter atp-binding protein
F0M21_RS01895	COG0765	amino acid transport
F0M21_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M21_RS01905	COG0583	DNA-binding transcription factor activity
F0M21_RS01910	COG0163	prenyltransferase activity
F0M21_RS01915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F0M21_RS01930	COG3104	oligopeptide transport
F0M21_RS01935	COG5434	Belongs to the glycosyl hydrolase 28 family
F0M21_RS01945	COG0697	spore germination
F0M21_RS01955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F0M21_RS01960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS01965	COG0456	acetyltransferase
F0M21_RS01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M21_RS01975	COG0765	amino acid transport
F0M21_RS01980	COG1126	abc transporter atp-binding protein
F0M21_RS01985	COG1473	amidohydrolase
F0M21_RS01990	COG2079	MmgE PrpD family protein
F0M21_RS01995	COG1136	(ABC) transporter
F0M21_RS02000	COG0577	efflux transmembrane transporter activity
F0M21_RS02005	COG0745	RESPONSE REGULATOR receiver
F0M21_RS02010	COG3850	Histidine kinase
F0M21_RS02010	COG5002	protein histidine kinase activity
F0M21_RS02015	COG0457	Tetratricopeptide repeat
F0M21_RS02030	COG0527	aspartate kinase activity
F0M21_RS02035	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS02040	COG4605	iron ion homeostasis
F0M21_RS02045	COG4604	ABC transporter, ATP-binding protein
F0M21_RS02050	COG4607	ABC-type enterochelin transport system periplasmic component
F0M21_RS02055	COG2814	Major facilitator Superfamily
F0M21_RS02060	COG1309	transcriptional regulator
F0M21_RS02065	COG0778	Nitroreductase
F0M21_RS02070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F0M21_RS02075	COG0640	Transcriptional regulator
F0M21_RS02080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M21_RS02085	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS02090	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS02095	COG4975	Glucose uptake
F0M21_RS02100	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS02105	COG4549	nuclear export factor GLE1
F0M21_RS02110	COG1276	copper resistance
F0M21_RS02110	COG2372	response to copper ion
F0M21_RS02115	COG1349	DNA-binding transcription factor activity
F0M21_RS02125	COG2213	PTS system mannitol-specific
F0M21_RS02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS02140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0M21_RS02150	COG0561	phosphatase activity
F0M21_RS02160	COG1914	H( )-stimulated, divalent metal cation uptake system
F0M21_RS02170	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F0M21_RS02175	COG1984	allophanate hydrolase subunit 2
F0M21_RS02180	COG1414	Transcriptional regulator
F0M21_RS02185	COG2755	lipolytic protein G-D-S-L family
F0M21_RS02195	COG2329	Antibiotic biosynthesis monooxygenase
F0M21_RS02200	COG0768	penicillin binding
F0M21_RS02205	COG4989	oxidoreductase activity
F0M21_RS02210	COG3711	transcriptional antiterminator
F0M21_RS02215	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS02220	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS02225	COG1917	Cupin 2, conserved barrel domain protein
F0M21_RS02230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M21_RS02235	COG3871	stress protein (general stress protein 26)
F0M21_RS02245	COG2814	Major facilitator Superfamily
F0M21_RS02250	COG1522	sequence-specific DNA binding
F0M21_RS02255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0M21_RS02255	COG0551	DNA topoisomerase type I activity
F0M21_RS02260	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F0M21_RS02265	COG3706	GGDEF domain
F0M21_RS02270	COG5298	Protein conserved in bacteria
F0M21_RS02275	COG1215	transferase activity, transferring glycosyl groups
F0M21_RS02285	COG0531	amino acid
F0M21_RS02290	COG0494	nUDIX hydrolase
F0M21_RS02295	COG0028	Belongs to the TPP enzyme family
F0M21_RS02325	COG0457	Tetratricopeptide repeat
F0M21_RS02355	COG1914	H( )-stimulated, divalent metal cation uptake system
F0M21_RS02370	COG4876	unkown
F0M21_RS02380	COG2076	Multidrug Resistance protein
F0M21_RS02385	COG2217	Heavy metal translocating P-type atpase
F0M21_RS02390	COG3729	General stress protein
F0M21_RS02395	COG0662	Cupin 2, conserved barrel domain protein
F0M21_RS02400	COG2329	Antibiotic biosynthesis monooxygenase
F0M21_RS02405	COG3546	catalase activity
F0M21_RS02410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0M21_RS02415	COG3290	protein histidine kinase activity
F0M21_RS02420	COG4565	transcriptional regulatory protein
F0M21_RS02425	COG1301	dicarboxylic acid transport
F0M21_RS02430	COG0628	permease
F0M21_RS02435	COG1131	(ABC) transporter
F0M21_RS02440	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F0M21_RS02450	COG1960	acyl-CoA dehydrogenase activity
F0M21_RS02470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS02480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F0M21_RS02485	COG0513	Belongs to the DEAD box helicase family
F0M21_RS02490	COG3402	PFAM membrane-flanked domain
F0M21_RS02495	COG3428	Bacterial PH domain
F0M21_RS02500	COG0705	Rhomboid family
F0M21_RS02510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F0M21_RS02515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0M21_RS02520	COG0864	Transcriptional regulator
F0M21_RS02525	COG2337	Toxic component of a toxin-antitoxin (TA) module
F0M21_RS02530	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS02535	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS02540	COG2172	sigma factor antagonist activity
F0M21_RS02545	COG2208	phosphoserine phosphatase activity
F0M21_RS02550	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS02560	COG1191	sigma factor activity
F0M21_RS02565	COG2208	phosphoserine phosphatase activity
F0M21_RS02570	COG2183	response to ionizing radiation
F0M21_RS02620	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0M21_RS02630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F0M21_RS02635	COG1522	sequence-specific DNA binding
F0M21_RS02655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M21_RS02660	COG0477	Major facilitator Superfamily
F0M21_RS02665	COG1846	Transcriptional regulator
F0M21_RS02675	COG2030	dehydratase
F0M21_RS02690	COG1959	2 iron, 2 sulfur cluster binding
F0M21_RS02695	COG2910	NAD(P)H-binding
F0M21_RS02700	COG1309	transcriptional regulator
F0M21_RS02705	COG0300	oxidoreductase activity
F0M21_RS02715	COG0604	alcohol dehydrogenase
F0M21_RS02725	COG3239	Fatty acid desaturase
F0M21_RS02735	COG1278	Cold shock
F0M21_RS02740	COG1329	Transcriptional regulator
F0M21_RS02745	COG1937	Protein conserved in bacteria
F0M21_RS02750	COG2210	Belongs to the sulfur carrier protein TusA family
F0M21_RS02760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0M21_RS02760	COG0425	Belongs to the sulfur carrier protein TusA family
F0M21_RS02765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS02765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0M21_RS02770	COG0425	Belongs to the sulfur carrier protein TusA family
F0M21_RS02775	COG0730	response to heat
F0M21_RS02780	COG1794	racemase activity, acting on amino acids and derivatives
F0M21_RS02795	COG1846	Transcriptional regulator
F0M21_RS02795	COG0456	acetyltransferase
F0M21_RS02800	COG2271	Major facilitator Superfamily
F0M21_RS02805	COG3621	Patatin-like phospholipase
F0M21_RS02815	COG0662	Cupin 2, conserved barrel domain protein
F0M21_RS02830	COG0277	FAD linked oxidase domain protein
F0M21_RS02855	COG0662	Cupin 2, conserved barrel domain protein
F0M21_RS02860	COG2318	DinB family
F0M21_RS02865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0M21_RS02900	COG0351	phosphomethylpyrimidine kinase
F0M21_RS02915	COG1064	alcohol dehydrogenase
F0M21_RS02920	COG0789	Transcriptional regulator
F0M21_RS02930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M21_RS02965	COG2814	Major facilitator Superfamily
F0M21_RS02970	COG1309	transcriptional regulator
F0M21_RS02975	COG0697	spore germination
F0M21_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M21_RS02985	COG5577	PFAM Coat F domain
F0M21_RS02995	COG1063	alcohol dehydrogenase
F0M21_RS03000	COG5577	PFAM Coat F domain
F0M21_RS03015	COG4585	Histidine kinase
F0M21_RS03020	COG2197	response regulator
F0M21_RS03025	COG2409	Drug exporters of the RND superfamily
F0M21_RS03030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F0M21_RS03035	COG0488	(ABC) transporter
F0M21_RS03040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M21_RS03045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS03055	COG2814	Major facilitator Superfamily
F0M21_RS03060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0M21_RS03070	COG0730	response to heat
F0M21_RS03075	COG0456	acetyltransferase
F0M21_RS03080	COG0789	Transcriptional regulator
F0M21_RS03080	COG4978	Transcriptional regulator
F0M21_RS03085	COG0697	spore germination
F0M21_RS03090	COG1051	belongs to the nudix hydrolase family
F0M21_RS03095	COG2226	methyltransferase
F0M21_RS03105	COG1802	Transcriptional regulator
F0M21_RS03110	COG1819	glycosyl
F0M21_RS03125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0M21_RS03130	COG1388	LysM domain
F0M21_RS03135	COG2814	Major facilitator Superfamily
F0M21_RS03140	COG2188	Transcriptional regulator
F0M21_RS03145	COG2186	Transcriptional regulator
F0M21_RS03150	COG2807	transmembrane transport
F0M21_RS03155	COG2076	Multidrug Resistance protein
F0M21_RS03160	COG2076	Multidrug Resistance protein
F0M21_RS03165	COG1309	transcriptional regulator
F0M21_RS03170	COG0531	amino acid
F0M21_RS03180	COG3832	glyoxalase III activity
F0M21_RS03185	COG0604	alcohol dehydrogenase
F0M21_RS03190	COG2814	Major facilitator Superfamily
F0M21_RS03230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F0M21_RS03235	COG0802	atpase or kinase
F0M21_RS03240	COG1214	PFAM Peptidase M22, glycoprotease
F0M21_RS03245	COG0456	acetyltransferase
F0M21_RS03250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0M21_RS03255	COG0488	(ABC) transporter
F0M21_RS03270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0M21_RS03275	COG0805	protein transport
F0M21_RS03285	COG1266	CAAX protease self-immunity
F0M21_RS03300	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS03315	COG0457	Tetratricopeptide repeat
F0M21_RS03320	COG1063	alcohol dehydrogenase
F0M21_RS03325	COG2211	Major facilitator Superfamily
F0M21_RS03330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M21_RS03340	COG1842	Phage shock protein A
F0M21_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0M21_RS03350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F0M21_RS03355	COG4260	virion core protein, lumpy skin disease virus
F0M21_RS03360	COG2755	lipolytic protein G-D-S-L family
F0M21_RS03360	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F0M21_RS03370	COG1595	DNA-templated transcription, initiation
F0M21_RS03375	COG1063	alcohol dehydrogenase
F0M21_RS03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F0M21_RS03385	COG0823	Involved in the tonB-independent uptake of proteins
F0M21_RS03395	COG2132	Multicopper oxidase
F0M21_RS03400	COG1113	amino acid transport
F0M21_RS03405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0M21_RS03410	COG0714	Associated with various cellular activities
F0M21_RS03415	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
F0M21_RS03420	COG1305	Transglutaminase-like
F0M21_RS03440	COG2252	PERMEase
F0M21_RS03445	COG3064	Membrane
F0M21_RS03465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0M21_RS03470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F0M21_RS03475	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F0M21_RS03480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0M21_RS03485	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F0M21_RS03500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F0M21_RS03510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0M21_RS03515	COG0138	bifunctional purine biosynthesis protein purh
F0M21_RS03520	COG0151	Belongs to the GarS family
F0M21_RS03530	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F0M21_RS03535	COG1470	cell adhesion involved in biofilm formation
F0M21_RS03540	COG4496	protein, YerC YecD
F0M21_RS03545	COG0069	glutamate synthase activity
F0M21_RS03555	COG0210	DNA helicase
F0M21_RS03565	COG4851	CamS sex pheromone cAM373 precursor
F0M21_RS03570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F0M21_RS03575	COG1285	pathogenesis
F0M21_RS03580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M21_RS03600	COG1309	transcriptional regulator
F0M21_RS03605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0M21_RS03610	COG1597	lipid kinase activity
F0M21_RS03615	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0M21_RS03620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F0M21_RS03630	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F0M21_RS03660	COG5444	nuclease activity
F0M21_RS03685	COG3546	catalase activity
F0M21_RS03690	COG0454	-acetyltransferase
F0M21_RS03700	COG2323	membrane
F0M21_RS03705	COG2329	Antibiotic biosynthesis monooxygenase
F0M21_RS03710	COG0346	lactoylglutathione lyase activity
F0M21_RS03720	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS03725	COG5583	Uncharacterized small protein (DUF2292)
F0M21_RS03730	COG0196	riboflavin kinase activity
F0M21_RS03735	COG0670	Belongs to the BI1 family
F0M21_RS03740	COG1846	Transcriptional regulator
F0M21_RS03745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0M21_RS03755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0M21_RS03755	COG2124	cytochrome p450
F0M21_RS03770	COG1131	(ABC) transporter
F0M21_RS03815	COG4106	trans-aconitate 2-methyltransferase activity
F0M21_RS03820	COG1368	sulfuric ester hydrolase activity
F0M21_RS03825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0M21_RS03830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS03835	COG1442	glycosyl transferase family 8
F0M21_RS03840	COG1216	Glycosyl transferase, family 2
F0M21_RS03845	COG1442	glycosyl transferase family 8
F0M21_RS03850	COG2223	nitrite transmembrane transporter activity
F0M21_RS03855	COG0531	amino acid
F0M21_RS03860	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS03865	COG0840	transmembrane signaling receptor activity
F0M21_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS03875	COG0457	Tetratricopeptide repeat
F0M21_RS03875	COG0463	Glycosyl transferase, family 2
F0M21_RS03880	COG0488	(ABC) transporter
F0M21_RS03885	COG0789	Transcriptional regulator
F0M21_RS03890	COG2814	Major facilitator Superfamily
F0M21_RS03895	COG0488	(ABC) transporter
F0M21_RS03900	COG0513	Belongs to the DEAD box helicase family
F0M21_RS03910	COG2130	NADP-dependent
F0M21_RS03925	COG3866	Pectate lyase
F0M21_RS03930	COG0471	metal ion transport
F0M21_RS03955	COG3290	protein histidine kinase activity
F0M21_RS03960	COG4565	transcriptional regulatory protein
F0M21_RS03965	COG3181	Tripartite tricarboxylate transporter family receptor
F0M21_RS03970	COG2851	Citrate transporter
F0M21_RS03975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS03980	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
F0M21_RS03990	COG2258	MOSC domain
F0M21_RS04010	COG0024	Methionine aminopeptidase
F0M21_RS04015	COG1263	PTS System
F0M21_RS04015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS04025	COG1368	sulfuric ester hydrolase activity
F0M21_RS04035	COG0071	Belongs to the small heat shock protein (HSP20) family
F0M21_RS04050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS04050	COG1263	PTS System
F0M21_RS04055	COG0366	Alpha amylase catalytic
F0M21_RS04060	COG2188	Transcriptional regulator
F0M21_RS04065	COG0778	Nitroreductase
F0M21_RS04080	COG0737	Belongs to the 5'-nucleotidase family
F0M21_RS04085	COG0693	protein deglycase activity
F0M21_RS04090	COG1609	Transcriptional regulator
F0M21_RS04105	COG2814	Major facilitator Superfamily
F0M21_RS04115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0M21_RS04120	COG4980	gas vesicle protein
F0M21_RS04125	COG1295	ribonuclease BN
F0M21_RS04130	COG0477	Major facilitator Superfamily
F0M21_RS04135	COG0387	Pfam Sodium calcium exchanger
F0M21_RS04145	COG0668	transmembrane transport
F0M21_RS04150	COG0535	radical SAM domain protein
F0M21_RS04160	COG0726	polysaccharide deacetylase
F0M21_RS04165	COG2084	Dehydrogenase
F0M21_RS04175	COG0598	Magnesium transport protein CorA
F0M21_RS04180	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
F0M21_RS04185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0M21_RS04195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0M21_RS04200	COG4637	Psort location Cytoplasmic, score
F0M21_RS04205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0M21_RS04210	COG0022	dehydrogenase e1 component
F0M21_RS04215	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M21_RS04220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0M21_RS04225	COG3284	Transcriptional regulator
F0M21_RS04235	COG1486	melibiose metabolic process
F0M21_RS04240	COG1737	Transcriptional regulator
F0M21_RS04245	COG1263	PTS System
F0M21_RS04245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS04250	COG5434	Belongs to the glycosyl hydrolase 28 family
F0M21_RS04255	COG1132	(ABC) transporter
F0M21_RS04260	COG1132	(ABC) transporter
F0M21_RS04265	COG2259	Doxx family
F0M21_RS04270	COG2514	catechol 2,3-dioxygenase activity
F0M21_RS04285	COG1695	Transcriptional regulator
F0M21_RS04290	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0M21_RS04295	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
F0M21_RS04300	COG3848	Pyruvate phosphate dikinase
F0M21_RS04300	COG0574	Belongs to the PEP-utilizing enzyme family
F0M21_RS04305	COG2732	(Barnase) inhibitor
F0M21_RS04310	COG2318	DinB family
F0M21_RS04315	COG2814	Major facilitator Superfamily
F0M21_RS04320	COG1846	Transcriptional regulator
F0M21_RS04325	COG0392	lysyltransferase activity
F0M21_RS04325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F0M21_RS04330	COG0384	phenazine biosynthesis protein PhzF
F0M21_RS04335	COG0778	Nitroreductase
F0M21_RS04350	COG1090	epimerase
F0M21_RS04365	COG2814	Major facilitator Superfamily
F0M21_RS04375	COG3591	Belongs to the peptidase S1B family
F0M21_RS04390	COG3103	Sh3 type 3 domain protein
F0M21_RS04395	COG5658	integral membrane protein
F0M21_RS04400	COG0596	Alpha beta hydrolase
F0M21_RS04405	COG0463	Glycosyl transferase, family 2
F0M21_RS04410	COG4485	Bacterial membrane protein, YfhO
F0M21_RS04415	COG1988	membrane-bound metal-dependent
F0M21_RS04420	COG1194	a g-specific adenine glycosylase
F0M21_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS04450	COG1132	(ABC) transporter
F0M21_RS04455	COG4129	membrane
F0M21_RS04465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0M21_RS04470	COG0735	belongs to the Fur family
F0M21_RS04580	COG1757	Na H antiporter
F0M21_RS04585	COG3340	Belongs to the peptidase S51 family
F0M21_RS04595	COG0277	FAD linked oxidase domain protein
F0M21_RS04610	COG0753	catalase activity
F0M21_RS04625	COG1116	anion transmembrane transporter activity
F0M21_RS04630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0M21_RS04635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M21_RS04655	COG1476	TRANSCRIPTIONal
F0M21_RS04665	COG3382	B3 4 domain protein
F0M21_RS04670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0M21_RS04680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F0M21_RS04685	COG0789	Transcriptional regulator
F0M21_RS04690	COG1664	Polymer-forming cytoskeletal
F0M21_RS04695	COG1664	Polymer-forming cytoskeletal
F0M21_RS04700	COG2766	serine protein kinase
F0M21_RS04715	COG1846	Transcriptional regulator
F0M21_RS04720	COG1566	PFAM secretion protein HlyD family protein
F0M21_RS04725	COG2814	Major facilitator Superfamily
F0M21_RS04730	COG0655	NAD(P)H dehydrogenase (quinone) activity
F0M21_RS04745	COG1725	Transcriptional regulator
F0M21_RS04750	COG1131	(ABC) transporter
F0M21_RS04755	COG1131	(ABC) transporter
F0M21_RS04760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F0M21_RS04765	COG1278	Cold shock
F0M21_RS04775	COG1464	Belongs to the NlpA lipoprotein family
F0M21_RS04780	COG3706	GGDEF domain
F0M21_RS04785	COG1823	symporter activity
F0M21_RS04805	COG5577	PFAM Coat F domain
F0M21_RS04815	COG3764	Sortase (surface protein transpeptidase)
F0M21_RS04820	COG0564	pseudouridine synthase activity
F0M21_RS04830	COG0517	IMP dehydrogenase activity
F0M21_RS04835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0M21_RS04840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0M21_RS04840	COG3153	acetyltransferase
F0M21_RS04845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M21_RS04850	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
F0M21_RS04855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0M21_RS04865	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0M21_RS04870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0M21_RS04875	COG2203	Gaf domain
F0M21_RS04875	COG4585	Histidine kinase
F0M21_RS04880	COG2197	response regulator
F0M21_RS04885	COG0431	NADPH-dependent FMN reductase
F0M21_RS04900	COG1388	LysM domain
F0M21_RS04900	COG0791	NLP P60 protein
F0M21_RS04905	COG1959	2 iron, 2 sulfur cluster binding
F0M21_RS04915	COG0668	transmembrane transport
F0M21_RS04920	COG2719	SpoVR family
F0M21_RS04925	COG1785	Belongs to the alkaline phosphatase family
F0M21_RS04930	COG1388	LysM domain
F0M21_RS04930	COG0791	NLP P60 protein
F0M21_RS04935	COG0583	DNA-binding transcription factor activity
F0M21_RS04940	COG0372	Belongs to the citrate synthase family
F0M21_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS04950	COG0531	amino acid
F0M21_RS04955	COG0733	neurotransmitter:sodium symporter activity
F0M21_RS04970	COG1595	DNA-templated transcription, initiation
F0M21_RS04975	COG0204	Acyl-transferase
F0M21_RS04980	COG1253	flavin adenine dinucleotide binding
F0M21_RS04985	COG0789	Transcriptional regulator
F0M21_RS04990	COG0436	Aminotransferase
F0M21_RS04995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0M21_RS05000	COG1253	flavin adenine dinucleotide binding
F0M21_RS05005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0M21_RS05010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0M21_RS05015	COG0584	glycerophosphoryl diester phosphodiesterase
F0M21_RS05025	COG0668	transmembrane transport
F0M21_RS05030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0M21_RS05035	COG0726	polysaccharide deacetylase
F0M21_RS05040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS05045	COG3226	Transcriptional regulator
F0M21_RS05055	COG0589	response to stress
F0M21_RS05060	COG1132	(ABC) transporter
F0M21_RS05065	COG1132	(ABC) transporter
F0M21_RS05070	COG0702	epimerase
F0M21_RS05090	COG0189	ligase activity
F0M21_RS05095	COG0189	ligase activity
F0M21_RS05110	COG4335	DNA alkylation repair
F0M21_RS05115	COG0561	phosphatase activity
F0M21_RS05120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0M21_RS05130	COG0475	glutathione-regulated potassium exporter activity
F0M21_RS05135	COG0490	domain, Protein
F0M21_RS05145	COG1024	Enoyl-CoA hydratase
F0M21_RS05155	COG4152	abc transporter atp-binding protein
F0M21_RS05160	COG1668	transmembrane transport
F0M21_RS05165	COG0420	3'-5' exonuclease activity
F0M21_RS05170	COG4717	serine-type aminopeptidase activity
F0M21_RS05185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0M21_RS05225	COG4980	gas vesicle protein
F0M21_RS05240	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0M21_RS05245	COG0537	adenosine 5'-monophosphoramidase activity
F0M21_RS05250	COG1131	(ABC) transporter
F0M21_RS05255	COG4473	ABC transporter
F0M21_RS05265	COG1473	amidohydrolase
F0M21_RS05270	COG3069	C4-dicarboxylate transmembrane transporter activity
F0M21_RS05275	COG2329	Antibiotic biosynthesis monooxygenase
F0M21_RS05280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0M21_RS05290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0M21_RS05295	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
F0M21_RS05300	COG1309	transcriptional regulator
F0M21_RS05305	COG1511	domain protein
F0M21_RS05310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0M21_RS05320	COG1363	Peptidase, m42
F0M21_RS05325	COG1301	dicarboxylic acid transport
F0M21_RS05335	COG1234	tRNA 3'-trailer cleavage
F0M21_RS05340	COG0095	Lipoate-protein ligase
F0M21_RS05345	COG0702	epimerase
F0M21_RS05350	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS05360	COG0501	Belongs to the peptidase M48B family
F0M21_RS05365	COG1404	Belongs to the peptidase S8 family
F0M21_RS05375	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
F0M21_RS05380	COG0406	alpha-ribazole phosphatase activity
F0M21_RS05385	COG0183	Belongs to the thiolase family
F0M21_RS05390	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS05395	COG1268	BioY protein
F0M21_RS05400	COG0840	transmembrane signaling receptor activity
F0M21_RS05405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M21_RS05405	COG0723	plastoquinol--plastocyanin reductase activity
F0M21_RS05410	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS05420	COG4903	ComK protein
F0M21_RS05430	COG5646	InterPro IPR014922
F0M21_RS05455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M21_RS05470	COG0398	Pfam SNARE associated Golgi protein
F0M21_RS05475	COG0681	Belongs to the peptidase S26 family
F0M21_RS05480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0M21_RS05485	COG1846	Transcriptional regulator
F0M21_RS05490	COG3180	Ammonia monooxygenase
F0M21_RS05495	COG2814	Major facilitator Superfamily
F0M21_RS05505	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
F0M21_RS05510	COG2323	membrane
F0M21_RS05525	COG0420	3'-5' exonuclease activity
F0M21_RS05530	COG0419	ATPase involved in DNA repair
F0M21_RS05535	COG1403	HNH endonuclease
F0M21_RS05575	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0M21_RS05595	COG0367	asparagine synthase
F0M21_RS05600	COG1562	ergosterol biosynthetic process
F0M21_RS05605	COG0534	Mate efflux family protein
F0M21_RS05610	COG1917	Cupin 2, conserved barrel domain protein
F0M21_RS05610	COG2207	Transcriptional regulator
F0M21_RS05615	COG2318	DinB family
F0M21_RS05625	COG1357	PFAM Pentapeptide repeats (8 copies)
F0M21_RS05630	COG2153	protein acetylation
F0M21_RS05635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F0M21_RS05635	COG0646	methionine synthase
F0M21_RS05645	COG2996	Protein conserved in bacteria
F0M21_RS05650	COG1744	ABC transporter substrate-binding protein PnrA-like
F0M21_RS05655	COG0840	transmembrane signaling receptor activity
F0M21_RS05660	COG2124	cytochrome p450
F0M21_RS05670	COG1307	EDD domain protein, DegV family
F0M21_RS05675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS05690	COG0561	phosphatase activity
F0M21_RS05695	COG1073	alpha beta
F0M21_RS05700	COG2151	metal-sulfur cluster biosynthetic enzyme
F0M21_RS05710	COG0277	FAD linked oxidase domain protein
F0M21_RS05715	COG2271	Major facilitator Superfamily
F0M21_RS05725	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F0M21_RS05735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0M21_RS05740	COG0505	Belongs to the CarA family
F0M21_RS05745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0M21_RS05750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F0M21_RS05770	COG2267	carboxylic ester hydrolase activity
F0M21_RS05780	COG1744	ABC transporter substrate-binding protein PnrA-like
F0M21_RS05795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0M21_RS05800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0M21_RS05805	COG5504	Zn-dependent protease
F0M21_RS05810	COG0444	Belongs to the ABC transporter superfamily
F0M21_RS05815	COG4608	Belongs to the ABC transporter superfamily
F0M21_RS05825	COG0601	transmembrane transport
F0M21_RS05830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M21_RS05840	COG0180	Tryptophanyl-tRNA synthetase
F0M21_RS05845	COG4166	transmembrane transport
F0M21_RS05850	COG0601	transmembrane transport
F0M21_RS05855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M21_RS05860	COG0444	Belongs to the ABC transporter superfamily
F0M21_RS05865	COG4608	Belongs to the ABC transporter superfamily
F0M21_RS05875	COG0456	acetyltransferase
F0M21_RS05880	COG1393	Belongs to the ArsC family
F0M21_RS05885	COG0861	Integral membrane protein TerC family
F0M21_RS05890	COG4862	establishment of competence for transformation
F0M21_RS05895	COG4469	Competence protein
F0M21_RS05900	COG1164	Oligoendopeptidase f
F0M21_RS05905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0M21_RS05910	COG2346	COG2346, Truncated hemoglobins
F0M21_RS05915	COG0741	lytic transglycosylase activity
F0M21_RS05920	COG4116	CYTH
F0M21_RS05930	COG2357	RelA SpoT domain protein
F0M21_RS05935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0M21_RS05940	COG0564	pseudouridine synthase activity
F0M21_RS05955	COG0475	glutathione-regulated potassium exporter activity
F0M21_RS05955	COG0569	domain protein
F0M21_RS05960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F0M21_RS05965	COG0352	thiamine-phosphate diphosphorylase activity
F0M21_RS05970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M21_RS05975	COG2104	thiamine diphosphate biosynthetic process
F0M21_RS05985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0M21_RS05990	COG0351	phosphomethylpyrimidine kinase
F0M21_RS05995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0M21_RS06050	COG0210	DNA helicase
F0M21_RS06070	COG1131	(ABC) transporter
F0M21_RS06080	COG2153	protein acetylation
F0M21_RS06090	COG2382	esterase
F0M21_RS06095	COG0626	cystathionine gamma-synthase activity
F0M21_RS06100	COG0626	cystathionine gamma-synthase activity
F0M21_RS06120	COG5444	nuclease activity
F0M21_RS06160	COG5444	nuclease activity
F0M21_RS06185	COG2367	Beta-lactamase
F0M21_RS06190	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F0M21_RS06195	COG0477	Major facilitator Superfamily
F0M21_RS06200	COG1846	Transcriptional regulator
F0M21_RS06210	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
F0M21_RS06215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0M21_RS06220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F0M21_RS06225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS06225	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS06230	COG1447	Phosphotransferase system cellobiose-specific component IIA
F0M21_RS06260	COG1285	pathogenesis
F0M21_RS06275	COG2205	protein histidine kinase activity
F0M21_RS06285	COG3383	formate dehydrogenase (NAD+) activity
F0M21_RS06290	COG2427	Protein of unknown function (DUF1641)
F0M21_RS06295	COG2124	cytochrome p450
F0M21_RS06300	COG1819	glycosyl
F0M21_RS06310	COG1587	Uroporphyrinogen-III synthase
F0M21_RS06315	COG0390	transport system, permease component
F0M21_RS06320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0M21_RS06325	COG0697	spore germination
F0M21_RS06330	COG4297	protein containing double-stranded beta helix domain
F0M21_RS06340	COG1252	NADH dehydrogenase
F0M21_RS06350	COG2211	Major facilitator Superfamily
F0M21_RS06355	COG1609	Transcriptional regulator
F0M21_RS06360	COG0246	Mannitol dehydrogenase
F0M21_RS06365	COG2721	sulfolactate sulfo-lyase activity
F0M21_RS06370	COG0730	response to heat
F0M21_RS06375	COG2318	DinB family
F0M21_RS06380	COG0457	Tetratricopeptide repeat
F0M21_RS06390	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS06390	COG1388	LysM domain
F0M21_RS06390	COG5632	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS06400	COG4195	phage-related replication protein
F0M21_RS06410	COG2856	Zn peptidase
F0M21_RS06415	COG1396	sequence-specific DNA binding
F0M21_RS06430	COG1484	DNA-dependent DNA replication
F0M21_RS06445	COG1595	DNA-templated transcription, initiation
F0M21_RS06485	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS06485	COG5632	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS06500	COG0306	phosphate transporter
F0M21_RS06505	COG1392	Phosphate transport regulator
F0M21_RS06510	COG0531	amino acid
F0M21_RS06515	COG0346	lactoylglutathione lyase activity
F0M21_RS06520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0M21_RS06525	COG0463	Glycosyl transferase, family 2
F0M21_RS06530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0M21_RS06535	COG0477	Major facilitator Superfamily
F0M21_RS06540	COG2362	D-Aminopeptidase
F0M21_RS06545	COG0601	transmembrane transport
F0M21_RS06550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0M21_RS06555	COG0444	Belongs to the ABC transporter superfamily
F0M21_RS06560	COG4166	transmembrane transport
F0M21_RS06565	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0M21_RS06570	COG4948	Mandelate Racemase Muconate Lactonizing
F0M21_RS06575	COG0791	NLP P60 protein
F0M21_RS06580	COG4608	Belongs to the ABC transporter superfamily
F0M21_RS06585	COG2706	6-phosphogluconolactonase activity
F0M21_RS06590	COG1834	amidinotransferase
F0M21_RS06595	COG1607	acyl-coa hydrolase
F0M21_RS06600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M21_RS06605	COG2076	Multidrug Resistance protein
F0M21_RS06610	COG2076	Multidrug Resistance protein
F0M21_RS06615	COG0788	formyltetrahydrofolate deformylase activity
F0M21_RS06620	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0M21_RS06630	COG1764	response to oxidative stress
F0M21_RS06635	COG1846	Transcriptional regulator
F0M21_RS06640	COG1764	response to oxidative stress
F0M21_RS06655	COG0457	Tetratricopeptide repeat
F0M21_RS06655	COG0463	Glycosyl transferase, family 2
F0M21_RS06665	COG2814	Major facilitator Superfamily
F0M21_RS06670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0M21_RS06680	COG1404	Belongs to the peptidase S8 family
F0M21_RS06685	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS06690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F0M21_RS06695	COG1122	ATPase activity
F0M21_RS06700	COG4721	ABC-type cobalt transport system, permease component
F0M21_RS06705	COG1388	LysM domain
F0M21_RS06705	COG3858	chitin binding
F0M21_RS06725	COG2239	Acts as a magnesium transporter
F0M21_RS06730	COG0789	Transcriptional regulator
F0M21_RS06745	COG1846	Transcriptional regulator
F0M21_RS06750	COG0726	polysaccharide deacetylase
F0M21_RS06755	COG3285	dna ligase
F0M21_RS06755	COG1793	dna ligase
F0M21_RS06760	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
F0M21_RS06765	COG0586	Pfam SNARE associated Golgi protein
F0M21_RS06770	COG0861	Integral membrane protein TerC family
F0M21_RS06775	COG1191	sigma factor activity
F0M21_RS06800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0M21_RS06805	COG2323	membrane
F0M21_RS06815	COG3594	Acyltransferase
F0M21_RS06820	COG5002	protein histidine kinase activity
F0M21_RS06825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0M21_RS06840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0M21_RS06845	COG0436	Aminotransferase
F0M21_RS06875	COG3852	Histidine kinase
F0M21_RS06880	COG1846	Transcriptional regulator
F0M21_RS06885	COG1360	Flagellar Motor Protein
F0M21_RS06890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F0M21_RS06895	COG0542	response to heat
F0M21_RS06905	COG3949	Membrane
F0M21_RS06920	COG0720	synthase
F0M21_RS06925	COG0602	queuosine metabolic process
F0M21_RS06935	COG1733	regulation of RNA biosynthetic process
F0M21_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS06955	COG4873	Protein conserved in bacteria
F0M21_RS06965	COG3773	Cell wall hydrolase
F0M21_RS06970	COG2244	polysaccharide biosynthetic process
F0M21_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS06980	COG2217	Heavy metal translocating P-type atpase
F0M21_RS06985	COG0006	proline dipeptidase activity
F0M21_RS06990	COG1609	Transcriptional regulator
F0M21_RS06995	COG3711	transcriptional antiterminator
F0M21_RS07000	COG2190	(PTS) system
F0M21_RS07000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS07000	COG1263	PTS System
F0M21_RS07005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS07010	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0M21_RS07020	COG1533	DNA photolyase activity
F0M21_RS07025	COG0840	transmembrane signaling receptor activity
F0M21_RS07030	COG2084	Dehydrogenase
F0M21_RS07045	COG2340	Cysteine-rich secretory protein family
F0M21_RS07050	COG0768	penicillin binding
F0M21_RS07055	COG4191	Histidine kinase
F0M21_RS07060	COG0436	Aminotransferase
F0M21_RS07070	COG0784	Response regulator, receiver
F0M21_RS07070	COG0835	chemotaxis
F0M21_RS07080	COG2814	Major facilitator Superfamily
F0M21_RS07085	COG1376	ErfK ybiS ycfS ynhG family protein
F0M21_RS07090	COG1408	metallophosphoesterase
F0M21_RS07095	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS07105	COG2200	EAL domain
F0M21_RS07110	COG4703	Protein of unknown function (DUF1797)
F0M21_RS07115	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
F0M21_RS07125	COG0517	IMP dehydrogenase activity
F0M21_RS07130	COG0583	DNA-binding transcription factor activity
F0M21_RS07135	COG0716	FMN binding
F0M21_RS07145	COG0716	FMN binding
F0M21_RS07165	COG0668	transmembrane transport
F0M21_RS07170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS07190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0M21_RS07195	COG0303	'Molybdopterin
F0M21_RS07200	COG1763	Mo-molybdopterin cofactor biosynthetic process
F0M21_RS07205	COG0314	molybdopterin synthase activity
F0M21_RS07210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F0M21_RS07220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0M21_RS07225	COG1136	(ABC) transporter
F0M21_RS07230	COG0577	efflux transmembrane transporter activity
F0M21_RS07235	COG1349	DNA-binding transcription factor activity
F0M21_RS07240	COG1105	Belongs to the carbohydrate kinase PfkB family
F0M21_RS07245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M21_RS07245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M21_RS07245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS07250	COG0681	Belongs to the peptidase S26 family
F0M21_RS07260	COG0488	(ABC) transporter
F0M21_RS07265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0M21_RS07270	COG2309	aminopeptidase activity
F0M21_RS07280	COG1077	Cell shape determining protein MreB Mrl
F0M21_RS07290	COG2002	toxin-antitoxin pair type II binding
F0M21_RS07295	COG3852	Histidine kinase
F0M21_RS07300	COG2105	PFAM AIG2 family protein
F0M21_RS07300	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F0M21_RS07305	COG0569	domain protein
F0M21_RS07315	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F0M21_RS07325	COG0561	phosphatase activity
F0M21_RS07330	COG0242	peptide deformylase activity
F0M21_RS07340	COG0497	DNA recombination
F0M21_RS07355	COG3321	synthase
F0M21_RS07355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS07355	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS07355	COG4221	oxidoreductase activity
F0M21_RS07360	COG3321	synthase
F0M21_RS07360	COG0300	oxidoreductase activity
F0M21_RS07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS07360	COG4221	oxidoreductase activity
F0M21_RS07365	COG3321	synthase
F0M21_RS07365	COG4221	oxidoreductase activity
F0M21_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS07365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS07370	COG4221	oxidoreductase activity
F0M21_RS07370	COG3321	synthase
F0M21_RS07370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS07370	COG0300	oxidoreductase activity
F0M21_RS07375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS07375	COG0300	oxidoreductase activity
F0M21_RS07375	COG3321	synthase
F0M21_RS07375	COG4221	oxidoreductase activity
F0M21_RS07380	COG0300	oxidoreductase activity
F0M21_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS07380	COG4221	oxidoreductase activity
F0M21_RS07380	COG3321	synthase
F0M21_RS07385	COG4221	oxidoreductase activity
F0M21_RS07385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS07385	COG3321	synthase
F0M21_RS07385	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS07390	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0M21_RS07395	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0M21_RS07400	COG0022	dehydrogenase e1 component
F0M21_RS07405	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M21_RS07410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0M21_RS07415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS07430	COG1982	Orn Lys Arg decarboxylase major
F0M21_RS07455	COG0483	inositol monophosphate 1-phosphatase activity
F0M21_RS07465	COG3227	Zinc metalloprotease (Elastase)
F0M21_RS07480	COG1595	DNA-templated transcription, initiation
F0M21_RS07500	COG1217	gtp-binding protein TYPA
F0M21_RS07510	COG4896	Protein conserved in bacteria
F0M21_RS07520	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
F0M21_RS07525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0M21_RS07530	COG2066	Belongs to the glutaminase family
F0M21_RS07540	COG0772	Belongs to the SEDS family
F0M21_RS07545	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F0M21_RS07560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0M21_RS07560	COG2010	Cytochrome c
F0M21_RS07565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0M21_RS07570	COG1845	cytochrome c oxidase, subunit III
F0M21_RS07575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0M21_RS07580	COG3336	cytochrome c oxidase
F0M21_RS07590	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F0M21_RS07595	COG2340	Cysteine-rich secretory protein family
F0M21_RS07610	COG3679	Belongs to the UPF0342 family
F0M21_RS07620	COG0742	ribosomal rna small subunit methyltransferase
F0M21_RS07630	COG3314	Sporulation integral membrane protein YlbJ
F0M21_RS07635	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0M21_RS07640	COG3480	Lon protease (S16) C-terminal proteolytic domain
F0M21_RS07650	COG1399	metal-binding, possibly nucleic acid-binding protein
F0M21_RS07670	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0M21_RS07690	COG4839	cell division protein FtsL
F0M21_RS07695	COG0768	penicillin binding
F0M21_RS07700	COG0768	penicillin binding
F0M21_RS07720	COG0772	Belongs to the SEDS family
F0M21_RS07735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0M21_RS07740	COG0849	cell division
F0M21_RS07745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0M21_RS07750	COG1404	Belongs to the peptidase S8 family
F0M21_RS07750	COG4412	M6 family metalloprotease domain protein
F0M21_RS07760	COG1191	sigma factor activity
F0M21_RS07765	COG1191	sigma factor activity
F0M21_RS07770	COG1119	ATPase activity
F0M21_RS07775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M21_RS07780	COG1873	PFAM PRC-barrel domain
F0M21_RS07785	COG1496	oxidoreductase activity
F0M21_RS07790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0M21_RS07800	COG0762	integral membrane protein
F0M21_RS07805	COG2302	S4 RNA-binding domain
F0M21_RS07810	COG3599	regulation of cell shape
F0M21_RS07815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0M21_RS07820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0M21_RS07830	COG0564	pseudouridine synthase activity
F0M21_RS07840	COG2233	PERMEase
F0M21_RS07850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F0M21_RS07855	COG0505	Belongs to the CarA family
F0M21_RS07860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0M21_RS07875	COG0284	orotidine-5'-phosphate decarboxylase activity
F0M21_RS07880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0M21_RS07890	COG0306	phosphate transporter
F0M21_RS07905	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0M21_RS07910	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
F0M21_RS07915	COG1648	precorrin-2 dehydrogenase activity
F0M21_RS07930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F0M21_RS07935	COG1561	YicC-like family, N-terminal region
F0M21_RS07945	COG0194	GDP metabolic process
F0M21_RS07955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0M21_RS07960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0M21_RS07965	COG0242	peptide deformylase activity
F0M21_RS07975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0M21_RS07975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0M21_RS07985	COG0631	protein serine/threonine phosphatase activity
F0M21_RS07990	COG2815	serine threonine protein kinase
F0M21_RS07990	COG0515	serine threonine protein kinase
F0M21_RS08000	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0M21_RS08005	COG1564	THIamine pyrophosphokinase
F0M21_RS08020	COG1302	Protein conserved in bacteria
F0M21_RS08025	COG1461	Dihydroxyacetone kinase
F0M21_RS08030	COG1760	l-serine dehydratase
F0M21_RS08035	COG1760	l-serine dehydratase
F0M21_RS08040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0M21_RS08055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0M21_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS08075	COG1196	nuclear chromosome segregation
F0M21_RS08080	COG0552	protein localization to endoplasmic reticulum
F0M21_RS08095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0M21_RS08105	COG1837	Belongs to the UPF0109 family
F0M21_RS08130	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F0M21_RS08145	COG2257	FlhB HrpN YscU SpaS Family
F0M21_RS08155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0M21_RS08160	COG0758	DNA mediated transformation
F0M21_RS08165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0M21_RS08175	COG4974	Belongs to the 'phage' integrase family
F0M21_RS08195	COG1815	bacterial-type flagellum-dependent cell motility
F0M21_RS08200	COG1558	bacterial-type flagellum-dependent cell motility
F0M21_RS08205	COG1677	Flagellar hook-basal body complex protein FliE
F0M21_RS08210	COG1766	The M ring may be actively involved in energy transduction
F0M21_RS08215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0M21_RS08220	COG1317	bacterial-type flagellum organization
F0M21_RS08225	COG1157	protein secretion by the type III secretion system
F0M21_RS08230	COG2882	bacterial-type flagellum organization
F0M21_RS08235	COG3334	PFAM MgtE intracellular
F0M21_RS08240	COG3144	bacterial-type flagellum assembly
F0M21_RS08245	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F0M21_RS08250	COG4786	Flagellar basal body rod
F0M21_RS08255	COG1582	Flagellar protein (FlbD)
F0M21_RS08260	COG1580	Controls the rotational direction of flagella during chemotaxis
F0M21_RS08265	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0M21_RS08270	COG1776	CheC inhibitor of MCP methylation
F0M21_RS08270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0M21_RS08275	COG2201	protein-glutamate methylesterase activity
F0M21_RS08280	COG3190	flagellar
F0M21_RS08285	COG1338	Plays a role in the flagellum-specific transport system
F0M21_RS08290	COG1987	bacterial-type flagellum assembly
F0M21_RS08295	COG1684	flagellar biosynthetic protein fliR
F0M21_RS08300	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0M21_RS08305	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0M21_RS08310	COG1419	protein localization to endoplasmic reticulum
F0M21_RS08315	COG0455	bacterial-type flagellum organization
F0M21_RS08320	COG2201	protein-glutamate methylesterase activity
F0M21_RS08325	COG2198	Histidine kinase
F0M21_RS08325	COG0643	Histidine kinase
F0M21_RS08330	COG0835	chemotaxis
F0M21_RS08335	COG1776	CheC inhibitor of MCP methylation
F0M21_RS08345	COG1191	sigma factor activity
F0M21_RS08375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0M21_RS08380	COG4589	Belongs to the CDS family
F0M21_RS08390	COG0750	zinc metalloprotease
F0M21_RS08400	COG2176	DNA-directed DNA polymerase activity
F0M21_RS08410	COG0195	Participates in both transcription termination and antitermination
F0M21_RS08415	COG2740	Nucleic-acid-binding protein implicated in transcription termination
F0M21_RS08420	COG1358	cellular component organization or biogenesis
F0M21_RS08430	COG1550	Protein conserved in bacteria
F0M21_RS08445	COG0196	riboflavin kinase activity
F0M21_RS08460	COG0726	polysaccharide deacetylase
F0M21_RS08465	COG0612	Peptidase, M16
F0M21_RS08470	COG1873	PFAM PRC-barrel domain
F0M21_RS08475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0M21_RS08480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0M21_RS08485	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0M21_RS08490	COG0527	aspartate kinase activity
F0M21_RS08500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F0M21_RS08505	COG0740	serine-type endopeptidase activity
F0M21_RS08515	COG1674	ftsk spoiiie
F0M21_RS08515	COG4980	gas vesicle protein
F0M21_RS08520	COG2188	Transcriptional regulator
F0M21_RS08525	COG2814	Major facilitator Superfamily
F0M21_RS08530	COG1846	Transcriptional regulator
F0M21_RS08535	COG1033	growth of symbiont in host cell
F0M21_RS08535	COG2409	Drug exporters of the RND superfamily
F0M21_RS08540	COG0612	Peptidase, M16
F0M21_RS08545	COG0612	Peptidase, M16
F0M21_RS08550	COG0300	oxidoreductase activity
F0M21_RS08565	COG1426	Protein conserved in bacteria
F0M21_RS08570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F0M21_RS08585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0M21_RS08595	COG1692	metallophosphoesterase
F0M21_RS08600	COG2359	stage V sporulation protein S
F0M21_RS08620	COG4550	Control of competence regulator ComK, YlbF/YmcA
F0M21_RS08670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS08675	COG3425	synthase
F0M21_RS08680	COG1024	Enoyl-CoA hydratase
F0M21_RS08685	COG1024	Enoyl-CoA hydratase
F0M21_RS08690	COG3321	synthase
F0M21_RS08690	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS08690	COG0300	oxidoreductase activity
F0M21_RS08690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS08695	COG3321	synthase
F0M21_RS08695	COG0300	oxidoreductase activity
F0M21_RS08695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS08695	COG4221	oxidoreductase activity
F0M21_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS08700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS08700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS08700	COG3321	synthase
F0M21_RS08700	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS08700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS08700	COG3321	synthase
F0M21_RS08700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS08705	COG4221	oxidoreductase activity
F0M21_RS08705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS08705	COG3321	synthase
F0M21_RS08710	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F0M21_RS08710	COG3321	synthase
F0M21_RS08710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0M21_RS08710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS08715	COG2124	cytochrome p450
F0M21_RS08720	COG3209	COG3209 Rhs family protein
F0M21_RS08725	COG3619	membrane
F0M21_RS08735	COG1404	Belongs to the peptidase S8 family
F0M21_RS08745	COG4195	phage-related replication protein
F0M21_RS08750	COG1764	response to oxidative stress
F0M21_RS08760	COG2076	Multidrug Resistance protein
F0M21_RS08800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0M21_RS08805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0M21_RS08810	COG4112	unkown
F0M21_RS08815	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS08825	COG0464	growth
F0M21_RS08830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0M21_RS08835	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
F0M21_RS08840	COG0789	Transcriptional regulator
F0M21_RS08845	COG0174	glutamine synthetase
F0M21_RS08875	COG2211	Major facilitator Superfamily
F0M21_RS08880	COG3507	Belongs to the glycosyl hydrolase 43 family
F0M21_RS08895	COG1070	Carbohydrate kinase
F0M21_RS08900	COG3848	Pyruvate phosphate dikinase
F0M21_RS08900	COG0574	Belongs to the PEP-utilizing enzyme family
F0M21_RS08930	COG1064	alcohol dehydrogenase
F0M21_RS08945	COG0456	acetyltransferase
F0M21_RS08980	COG3397	chitin binding
F0M21_RS09005	COG5434	Belongs to the glycosyl hydrolase 28 family
F0M21_RS09010	COG0756	dUTP diphosphatase activity
F0M21_RS09020	COG4195	phage-related replication protein
F0M21_RS09050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F0M21_RS09060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0M21_RS09080	COG0785	Cytochrome C biogenesis protein
F0M21_RS09085	COG2201	protein-glutamate methylesterase activity
F0M21_RS09090	COG4846	Membrane protein involved in cytochrome C biogenesis
F0M21_RS09100	COG0071	Belongs to the small heat shock protein (HSP20) family
F0M21_RS09115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0M21_RS09120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS09140	COG0824	Thioesterase
F0M21_RS09150	COG4841	protein insertion into membrane
F0M21_RS09160	COG1832	CoA-binding protein
F0M21_RS09165	COG0187	DNA topoisomerase II activity
F0M21_RS09170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F0M21_RS09180	COG1115	amino acid carrier protein
F0M21_RS09190	COG1063	alcohol dehydrogenase
F0M21_RS09195	COG0800	Aldolase
F0M21_RS09200	COG1312	Catalyzes the dehydration of D-mannonate
F0M21_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS09210	COG1609	Transcriptional regulator
F0M21_RS09215	COG2271	Major facilitator Superfamily
F0M21_RS09260	COG2205	protein histidine kinase activity
F0M21_RS09265	COG0745	RESPONSE REGULATOR receiver
F0M21_RS09275	COG3507	Belongs to the glycosyl hydrolase 43 family
F0M21_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS09305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0M21_RS09310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0M21_RS09315	COG2610	gluconate transmembrane transporter activity
F0M21_RS09320	COG2124	cytochrome p450
F0M21_RS09340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M21_RS09350	COG2246	polysaccharide biosynthetic process
F0M21_RS09355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0M21_RS09360	COG0586	Pfam SNARE associated Golgi protein
F0M21_RS09365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0M21_RS09370	COG1024	Enoyl-CoA hydratase
F0M21_RS09375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0M21_RS09380	COG0511	ligase activity, forming carbon-carbon bonds
F0M21_RS09385	COG0439	Biotin carboxylase
F0M21_RS09390	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS09395	COG1960	acyl-CoA dehydrogenase activity
F0M21_RS09400	COG1649	PFAM Uncharacterised BCR, COG1649
F0M21_RS09410	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F0M21_RS09410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS09415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS09420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS09425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS09430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS09440	COG2027	D-alanyl-D-alanine carboxypeptidase
F0M21_RS09445	COG2017	converts alpha-aldose to the beta-anomer
F0M21_RS09450	COG0534	Mate efflux family protein
F0M21_RS09465	COG0582	viral genome integration into host DNA
F0M21_RS09470	COG0166	Belongs to the GPI family
F0M21_RS09475	COG0405	Gamma-glutamyltransferase
F0M21_RS09480	COG2814	Major facilitator Superfamily
F0M21_RS09485	COG0640	Transcriptional regulator
F0M21_RS09500	COG0604	alcohol dehydrogenase
F0M21_RS09510	COG0493	'glutamate synthase
F0M21_RS09515	COG0067	glutamate synthase
F0M21_RS09515	COG0070	glutamate synthase
F0M21_RS09515	COG0069	glutamate synthase activity
F0M21_RS09520	COG0583	DNA-binding transcription factor activity
F0M21_RS09525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0M21_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS09560	COG0300	oxidoreductase activity
F0M21_RS09565	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
F0M21_RS09575	COG2814	Major facilitator Superfamily
F0M21_RS09580	COG1070	Carbohydrate kinase
F0M21_RS09585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M21_RS09590	COG0243	molybdopterin cofactor binding
F0M21_RS09620	COG5444	nuclease activity
F0M21_RS09625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M21_RS09630	COG2207	Transcriptional regulator
F0M21_RS09630	COG0662	Cupin 2, conserved barrel domain protein
F0M21_RS09635	COG1309	transcriptional regulator
F0M21_RS09640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS09650	COG0640	Transcriptional regulator
F0M21_RS09655	COG0741	lytic transglycosylase activity
F0M21_RS09660	COG2322	membrane
F0M21_RS09675	COG1619	proteins homologs of microcin C7 resistance protein MccF
F0M21_RS09685	COG3584	3D domain protein
F0M21_RS09685	COG1388	LysM domain
F0M21_RS09690	COG0514	ATP-dependent DNA helicase (RecQ)
F0M21_RS09700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F0M21_RS09705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0M21_RS09720	COG0071	Belongs to the small heat shock protein (HSP20) family
F0M21_RS09750	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS09755	COG1657	PFAM Prenyltransferase squalene oxidase
F0M21_RS09760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0M21_RS09765	COG0733	neurotransmitter:sodium symporter activity
F0M21_RS09770	COG0385	Bile acid
F0M21_RS09775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS09780	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M21_RS09790	COG4548	von Willebrand factor, type A
F0M21_RS09795	COG0714	Associated with various cellular activities
F0M21_RS09800	COG2032	superoxide dismutase activity
F0M21_RS09805	COG0791	NLP P60 protein
F0M21_RS09805	COG1388	LysM domain
F0M21_RS09810	COG1819	glycosyl
F0M21_RS09815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
F0M21_RS09820	COG0534	Mate efflux family protein
F0M21_RS09825	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS09830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0M21_RS09835	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0M21_RS09845	COG2962	Rard protein
F0M21_RS09860	COG1942	4-Oxalocrotonate Tautomerase
F0M21_RS09870	COG1733	regulation of RNA biosynthetic process
F0M21_RS09875	COG0778	Nitroreductase
F0M21_RS09880	COG0400	carboxylic ester hydrolase activity
F0M21_RS09885	COG0346	lactoylglutathione lyase activity
F0M21_RS09895	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0M21_RS09910	COG2723	6-phospho-beta-galactosidase activity
F0M21_RS09915	COG2188	Transcriptional regulator
F0M21_RS09920	COG0793	Belongs to the peptidase S41A family
F0M21_RS09920	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS09925	COG2226	methyltransferase
F0M21_RS09935	COG1876	peptidase activity
F0M21_RS09955	COG0671	phosphoesterase, PA-phosphatase related
F0M21_RS09985	COG1509	lysine 2,3-aminomutase activity
F0M21_RS09990	COG0456	acetyltransferase
F0M21_RS09995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M21_RS10000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0M21_RS10005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0M21_RS10010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F0M21_RS10025	COG0456	acetyltransferase
F0M21_RS10030	COG0463	Glycosyl transferase, family 2
F0M21_RS10045	COG4641	Protein conserved in bacteria
F0M21_RS10055	COG1086	Polysaccharide biosynthesis protein
F0M21_RS10085	COG1388	LysM domain
F0M21_RS10090	COG0457	Tetratricopeptide repeat
F0M21_RS10105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS10105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0M21_RS10120	COG4585	Histidine kinase
F0M21_RS10130	COG0730	response to heat
F0M21_RS10135	COG0730	response to heat
F0M21_RS10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F0M21_RS10185	COG1846	Transcriptional regulator
F0M21_RS10190	COG4698	Protein conserved in bacteria
F0M21_RS10195	COG2755	lipolytic protein G-D-S-L family
F0M21_RS10200	COG1999	signal sequence binding
F0M21_RS10210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0M21_RS10215	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F0M21_RS10220	COG1272	protein, Hemolysin III
F0M21_RS10225	COG0204	Acyl-transferase
F0M21_RS10230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F0M21_RS10245	COG2136	Putative SAM-dependent methyltransferase
F0M21_RS10245	COG2521	methyltransferase
F0M21_RS10260	COG1413	lyase activity
F0M21_RS10265	COG1418	mRNA catabolic process
F0M21_RS10270	COG0386	Belongs to the glutathione peroxidase family
F0M21_RS10280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0M21_RS10290	COG1278	Cold shock
F0M21_RS10310	COG0328	RNA-DNA hybrid ribonuclease activity
F0M21_RS10315	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F0M21_RS10320	COG0328	RNA-DNA hybrid ribonuclease activity
F0M21_RS10330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0M21_RS10345	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F0M21_RS10355	COG1755	Isoprenylcysteine carboxyl methyltransferase
F0M21_RS10360	COG3424	synthase
F0M21_RS10380	COG2323	membrane
F0M21_RS10385	COG1335	isochorismatase
F0M21_RS10395	COG2233	PERMEase
F0M21_RS10405	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F0M21_RS10410	COG1199	ATP-dependent helicase activity
F0M21_RS10430	COG0116	Belongs to the methyltransferase superfamily
F0M21_RS10460	COG3359	exonuclease
F0M21_RS10465	COG1205	dead DEAH box helicase
F0M21_RS10465	COG1111	helicase
F0M21_RS10470	COG2190	(PTS) system
F0M21_RS10475	COG0071	Belongs to the small heat shock protein (HSP20) family
F0M21_RS10515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0M21_RS10515	COG4499	WXG100 protein secretion system (Wss), protein YukC
F0M21_RS10525	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0M21_RS10530	COG3935	DnaD domain protein
F0M21_RS10540	COG0436	Aminotransferase
F0M21_RS10545	COG5353	protein conserved in bacteria
F0M21_RS10555	COG1199	ATP-dependent helicase activity
F0M21_RS10555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0M21_RS10585	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS10590	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0M21_RS10605	COG1694	Mazg nucleotide pyrophosphohydrolase
F0M21_RS10610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS10615	COG2140	Oxalate decarboxylase
F0M21_RS10625	COG4347	Protein of unknown function (DUF1405)
F0M21_RS10630	COG2010	Cytochrome c
F0M21_RS10630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0M21_RS10635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F0M21_RS10640	COG0723	plastoquinol--plastocyanin reductase activity
F0M21_RS10655	COG0457	Tetratricopeptide repeat
F0M21_RS10665	COG0287	Prephenate dehydrogenase
F0M21_RS10700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F0M21_RS10705	COG4401	Chorismate mutase type I
F0M21_RS10720	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F0M21_RS10725	COG0105	UTP biosynthetic process
F0M21_RS10730	COG0142	geranyltranstransferase activity
F0M21_RS10740	COG0142	geranyltranstransferase activity
F0M21_RS10755	COG0776	regulation of translation
F0M21_RS10760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
F0M21_RS10800	COG0539	negative regulation of cytoplasmic translation
F0M21_RS10815	COG2959	enzyme of heme biosynthesis
F0M21_RS10820	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS10820	COG3773	Cell wall hydrolase
F0M21_RS10825	COG2339	peptidase activity
F0M21_RS10830	COG0492	ferredoxin-NADP+ reductase activity
F0M21_RS10835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0M21_RS10840	COG4862	establishment of competence for transformation
F0M21_RS10845	COG1408	metallophosphoesterase
F0M21_RS10855	COG1388	LysM domain
F0M21_RS10860	COG1266	CAAX protease self-immunity
F0M21_RS10865	COG0514	ATP-dependent DNA helicase (RecQ)
F0M21_RS10870	COG4955	Helix-turn-helix domain
F0M21_RS10875	COG1141	Ferredoxin
F0M21_RS10880	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
F0M21_RS10885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0M21_RS10895	COG1595	DNA-templated transcription, initiation
F0M21_RS10900	COG5002	protein histidine kinase activity
F0M21_RS10905	COG0745	RESPONSE REGULATOR receiver
F0M21_RS10910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0M21_RS10915	COG1333	cytochrome c biogenesis protein
F0M21_RS10920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS10925	COG1187	pseudouridine synthase activity
F0M21_RS10930	COG0700	Nucleoside recognition
F0M21_RS10935	COG2715	membrane protein required for spore maturation
F0M21_RS10940	COG1686	Belongs to the peptidase S11 family
F0M21_RS10965	COG1547	Domain of unknown function (DUF309)
F0M21_RS10975	COG0456	acetyltransferase
F0M21_RS10990	COG0307	riboflavin synthase, alpha
F0M21_RS10995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0M21_RS10995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0M21_RS11005	COG0681	Belongs to the peptidase S26 family
F0M21_RS11015	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0M21_RS11020	COG4086	secreted protein
F0M21_RS11025	COG0019	diaminopimelate decarboxylase activity
F0M21_RS11030	COG0697	spore germination
F0M21_RS11045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F0M21_RS11065	COG1191	sigma factor activity
F0M21_RS11075	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS11080	COG1686	Belongs to the peptidase S11 family
F0M21_RS11085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F0M21_RS11090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F0M21_RS11095	COG4974	Belongs to the 'phage' integrase family
F0M21_RS11105	COG0735	belongs to the Fur family
F0M21_RS11110	COG1300	Membrane
F0M21_RS11125	COG0281	malic enzyme
F0M21_RS11130	COG1757	Na H antiporter
F0M21_RS11135	COG1027	Aspartate ammonia-lyase
F0M21_RS11140	COG0252	asparaginase activity
F0M21_RS11145	COG1396	sequence-specific DNA binding
F0M21_RS11150	COG1379	DNA repair
F0M21_RS11155	COG0494	nUDIX hydrolase
F0M21_RS11165	COG0667	Aldo Keto reductase
F0M21_RS11175	COG1073	alpha beta
F0M21_RS11185	COG4918	Iron-sulphur cluster biosynthesis
F0M21_RS11190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F0M21_RS11190	COG0456	acetyltransferase
F0M21_RS11195	COG2329	Antibiotic biosynthesis monooxygenase
F0M21_RS11200	COG0456	acetyltransferase
F0M21_RS11205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0M21_RS11220	COG0628	permease
F0M21_RS11230	COG0346	lactoylglutathione lyase activity
F0M21_RS11240	COG3048	D-serine ammonia-lyase activity
F0M21_RS11245	COG0300	oxidoreductase activity
F0M21_RS11250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS11255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F0M21_RS11260	COG1024	Enoyl-CoA hydratase
F0M21_RS11265	COG3425	synthase
F0M21_RS11270	COG2124	cytochrome p450
F0M21_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS11275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11275	COG3321	synthase
F0M21_RS11275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS11280	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS11280	COG3321	synthase
F0M21_RS11280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS11285	COG0300	oxidoreductase activity
F0M21_RS11285	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS11285	COG3321	synthase
F0M21_RS11285	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11290	COG0300	oxidoreductase activity
F0M21_RS11290	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11290	COG3321	synthase
F0M21_RS11290	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11295	COG3321	synthase
F0M21_RS11295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS11295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS11295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11300	COG0300	oxidoreductase activity
F0M21_RS11300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11300	COG3321	synthase
F0M21_RS11300	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS11305	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS11305	COG3321	synthase
F0M21_RS11305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS11305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0M21_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS11315	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS11330	COG2070	2-Nitropropane dioxygenase
F0M21_RS11330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0M21_RS11340	COG0250	Participates in transcription elongation, termination and antitermination
F0M21_RS11365	COG0596	Alpha beta hydrolase
F0M21_RS11380	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F0M21_RS11385	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F0M21_RS11400	COG0706	membrane insertase activity
F0M21_RS11405	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0M21_RS11410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F0M21_RS11415	COG0346	lactoylglutathione lyase activity
F0M21_RS11425	COG1376	ErfK ybiS ycfS ynhG family protein
F0M21_RS11430	COG4129	membrane
F0M21_RS11435	COG1126	abc transporter atp-binding protein
F0M21_RS11440	COG0765	amino acid transport
F0M21_RS11445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M21_RS11455	COG1597	lipid kinase activity
F0M21_RS11460	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0M21_RS11465	COG0022	dehydrogenase e1 component
F0M21_RS11470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F0M21_RS11475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0M21_RS11480	COG3426	butyrate kinase activity
F0M21_RS11485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0M21_RS11490	COG0280	phosphate acetyltransferase
F0M21_RS11495	COG3290	protein histidine kinase activity
F0M21_RS11495	COG3829	transcription factor binding
F0M21_RS11505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
F0M21_RS11510	COG2079	MmgE PrpD family protein
F0M21_RS11515	COG0372	Belongs to the citrate synthase family
F0M21_RS11520	COG1960	acyl-CoA dehydrogenase activity
F0M21_RS11525	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0M21_RS11530	COG0183	Belongs to the thiolase family
F0M21_RS11535	COG0584	glycerophosphoryl diester phosphodiesterase
F0M21_RS11540	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS11565	COG1902	pentaerythritol trinitrate reductase activity
F0M21_RS11580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0M21_RS11585	COG0745	RESPONSE REGULATOR receiver
F0M21_RS11590	COG0750	zinc metalloprotease
F0M21_RS11595	COG0497	DNA recombination
F0M21_RS11605	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
F0M21_RS11615	COG0142	geranyltranstransferase activity
F0M21_RS11625	COG1570	exodeoxyribonuclease VII activity
F0M21_RS11640	COG1302	Protein conserved in bacteria
F0M21_RS11645	COG0439	Biotin carboxylase
F0M21_RS11650	COG0511	ligase activity, forming carbon-carbon bonds
F0M21_RS11690	COG3854	ATPases associated with a variety of cellular activities
F0M21_RS11705	COG0006	proline dipeptidase activity
F0M21_RS11715	COG3872	metal-dependent enzyme
F0M21_RS11725	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0M21_RS11740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0M21_RS11760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0M21_RS11775	COG1396	sequence-specific DNA binding
F0M21_RS11785	COG0681	Belongs to the peptidase S26 family
F0M21_RS11810	COG4940	Competence protein ComGF
F0M21_RS11820	COG4970	Tfp pilus assembly protein FimT
F0M21_RS11825	COG4537	Required for transformation and DNA binding
F0M21_RS11830	COG1459	type II secretion system
F0M21_RS11835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F0M21_RS11840	COG0598	Magnesium transport protein CorA
F0M21_RS11845	COG1253	flavin adenine dinucleotide binding
F0M21_RS11850	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS11860	COG1393	Belongs to the ArsC family
F0M21_RS11870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS11880	COG0011	TIGRFAM Protein of
F0M21_RS11890	COG2866	Carboxypeptidase
F0M21_RS11895	COG1940	carbohydrate kinase activity
F0M21_RS11900	COG4483	Protein conserved in bacteria
F0M21_RS11905	COG1757	Na H antiporter
F0M21_RS11915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0M21_RS11930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0M21_RS11935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0M21_RS11940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F0M21_RS11945	COG0581	inorganic phosphate transmembrane transporter activity
F0M21_RS11950	COG0573	inorganic phosphate transmembrane transporter activity
F0M21_RS11955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F0M21_RS11965	COG0768	penicillin binding
F0M21_RS11970	COG0477	Major facilitator Superfamily
F0M21_RS11975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0M21_RS11980	COG2839	Protein conserved in bacteria
F0M21_RS11985	COG5521	maltodextrose utilization protein MalA
F0M21_RS11990	COG1388	LysM domain
F0M21_RS12000	COG4709	membrane
F0M21_RS12005	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
F0M21_RS12010	COG0735	belongs to the Fur family
F0M21_RS12015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS12030	COG0513	Belongs to the DEAD box helicase family
F0M21_RS12045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0M21_RS12050	COG2384	SAM-dependent methyltransferase
F0M21_RS12055	COG2010	Cytochrome c
F0M21_RS12060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0M21_RS12065	COG0358	DNA primase activity
F0M21_RS12080	COG0517	IMP dehydrogenase activity
F0M21_RS12085	COG0751	glycine-tRNA ligase activity
F0M21_RS12105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0M21_RS12110	COG0295	cytidine deaminase activity
F0M21_RS12115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F0M21_RS12125	COG1480	7TM receptor with intracellular HD hydrolase
F0M21_RS12130	COG1702	phosphate starvation-inducible protein PhoH
F0M21_RS12135	COG0561	phosphatase activity
F0M21_RS12150	COG4864	UPF0365 protein
F0M21_RS12155	COG1030	water channel activity
F0M21_RS12160	COG1610	YqeY-like protein
F0M21_RS12170	COG1283	sodium-dependent phosphate transmembrane transporter activity
F0M21_RS12175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0M21_RS12180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0M21_RS12210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0M21_RS12225	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS12240	COG1466	dna polymerase III delta subunit
F0M21_RS12255	COG2333	competence protein COMEC
F0M21_RS12255	COG0658	competence protein
F0M21_RS12260	COG2131	deaminase
F0M21_RS12265	COG1596	polysaccharide export
F0M21_RS12265	COG1555	photosystem II stabilization
F0M21_RS12270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F0M21_RS12275	COG2226	methyltransferase
F0M21_RS12280	COG0799	negative regulation of ribosome biogenesis
F0M21_RS12285	COG1713	HD superfamily hydrolase involved in NAD metabolism
F0M21_RS12295	COG1534	Rna-binding protein
F0M21_RS12300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0M21_RS12305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
F0M21_RS12310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
F0M21_RS12320	COG2755	lipolytic protein G-D-S-L family
F0M21_RS12330	COG0398	Pfam SNARE associated Golgi protein
F0M21_RS12365	COG0642	Histidine kinase
F0M21_RS12365	COG5002	protein histidine kinase activity
F0M21_RS12370	COG0745	RESPONSE REGULATOR receiver
F0M21_RS12375	COG2311	Membrane
F0M21_RS12380	COG0454	-acetyltransferase
F0M21_RS12385	COG0563	adenylate kinase activity
F0M21_RS12400	COG2318	DinB family
F0M21_RS12410	COG0561	phosphatase activity
F0M21_RS12415	COG0561	phosphatase activity
F0M21_RS12425	COG1482	cell wall glycoprotein biosynthetic process
F0M21_RS12430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS12430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M21_RS12430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0M21_RS12435	COG3711	transcriptional antiterminator
F0M21_RS12435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS12445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0M21_RS12450	COG0583	DNA-binding transcription factor activity
F0M21_RS12455	COG2814	Major facilitator Superfamily
F0M21_RS12460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0M21_RS12460	COG2124	cytochrome p450
F0M21_RS12465	COG1309	transcriptional regulator
F0M21_RS12470	COG2226	methyltransferase
F0M21_RS12485	COG2116	formate transmembrane transporter activity
F0M21_RS12490	COG5609	conserved protein (DUF2294)
F0M21_RS12495	COG3383	formate dehydrogenase (NAD+) activity
F0M21_RS12500	COG2427	Protein of unknown function (DUF1641)
F0M21_RS12510	COG0626	cystathionine gamma-synthase activity
F0M21_RS12515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0M21_RS12540	COG0768	penicillin binding
F0M21_RS12555	COG0826	peptidase U32
F0M21_RS12560	COG0826	peptidase U32
F0M21_RS12565	COG4122	O-methyltransferase activity
F0M21_RS12570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0M21_RS12595	COG0628	permease
F0M21_RS12600	COG1126	abc transporter atp-binding protein
F0M21_RS12605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M21_RS12610	COG0765	amino acid transport
F0M21_RS12615	COG0765	amino acid transport
F0M21_RS12630	COG3881	PFAM PRC-barrel domain
F0M21_RS12635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F0M21_RS12640	COG0457	Tetratricopeptide repeat
F0M21_RS12650	COG1104	cysteine desulfurase activity
F0M21_RS12655	COG1959	2 iron, 2 sulfur cluster binding
F0M21_RS12660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0M21_RS12665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0M21_RS12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS12685	COG3103	Sh3 type 3 domain protein
F0M21_RS12685	COG4991	sh3 domain protein
F0M21_RS12695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0M21_RS12705	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
F0M21_RS12705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F0M21_RS12710	COG5416	Lipopolysaccharide assembly protein A domain
F0M21_RS12715	COG0490	domain, Protein
F0M21_RS12720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0M21_RS12720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0M21_RS12730	COG2244	polysaccharide biosynthetic process
F0M21_RS12735	COG2323	membrane
F0M21_RS12745	COG1862	Preprotein translocase
F0M21_RS12790	COG1388	LysM domain
F0M21_RS12800	COG0157	Belongs to the NadC ModD family
F0M21_RS12805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0M21_RS12810	COG1104	cysteine desulfurase activity
F0M21_RS12815	COG1827	regulation of RNA biosynthetic process
F0M21_RS12820	COG0077	Prephenate dehydratase
F0M21_RS12835	COG3290	protein histidine kinase activity
F0M21_RS12845	COG2868	ribosomal protein
F0M21_RS12855	COG1994	Peptidase M50
F0M21_RS12860	COG0739	heme binding
F0M21_RS12865	COG2894	cell division
F0M21_RS12875	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F0M21_RS12885	COG1077	Cell shape determining protein MreB Mrl
F0M21_RS12905	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F0M21_RS12910	COG0285	dihydrofolate synthase activity
F0M21_RS12915	COG0525	valine-tRNA ligase activity
F0M21_RS12925	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F0M21_RS12930	COG1388	LysM domain
F0M21_RS12940	COG0113	porphobilinogen synthase activity
F0M21_RS12945	COG1587	Uroporphyrinogen-III synthase
F0M21_RS12955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0M21_RS12975	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F0M21_RS12980	COG1067	ATP-dependent peptidase activity
F0M21_RS12980	COG0470	DNA polymerase III
F0M21_RS12995	COG0457	Tetratricopeptide repeat
F0M21_RS12995	COG1477	protein flavinylation
F0M21_RS13010	COG0473	3-isopropylmalate dehydrogenase activity
F0M21_RS13025	COG0440	acetolactate synthase activity
F0M21_RS13030	COG0028	Belongs to the TPP enzyme family
F0M21_RS13055	COG0622	Phosphoesterase
F0M21_RS13060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0M21_RS13070	COG5401	PFAM Sporulation and spore germination
F0M21_RS13080	COG1846	Transcriptional regulator
F0M21_RS13085	COG2197	response regulator
F0M21_RS13090	COG0824	Thioesterase
F0M21_RS13095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0M21_RS13100	COG1053	succinate dehydrogenase
F0M21_RS13105	COG2009	succinate dehydrogenase
F0M21_RS13110	COG1719	4-vinyl reductase, 4VR
F0M21_RS13115	COG0527	aspartate kinase activity
F0M21_RS13130	COG3118	belongs to the thioredoxin family
F0M21_RS13135	COG3534	alpha-L-arabinofuranosidase
F0M21_RS13140	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
F0M21_RS13145	COG2086	electron transfer activity
F0M21_RS13150	COG1024	Enoyl-CoA hydratase
F0M21_RS13155	COG1309	transcriptional regulator
F0M21_RS13160	COG0318	PFAM AMP-dependent synthetase and ligase
F0M21_RS13170	COG3766	membrane
F0M21_RS13180	COG1796	DNA polymerase
F0M21_RS13180	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F0M21_RS13185	COG1286	toxin biosynthetic process
F0M21_RS13200	COG0072	phenylalanine-tRNA ligase activity
F0M21_RS13200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M21_RS13205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F0M21_RS13210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0M21_RS13220	COG3835	regulator
F0M21_RS13225	COG0277	FAD linked oxidase domain protein
F0M21_RS13230	COG0247	lactate metabolic process
F0M21_RS13235	COG1966	Carbon starvation protein
F0M21_RS13240	COG3534	alpha-L-arabinofuranosidase
F0M21_RS13245	COG0395	ABC-type sugar transport system, permease component
F0M21_RS13250	COG1175	transmembrane transport
F0M21_RS13255	COG1653	transport
F0M21_RS13265	COG0647	UMP catabolic process
F0M21_RS13270	COG0235	Class ii aldolase
F0M21_RS13275	COG1069	ribulokinase activity
F0M21_RS13280	COG2160	L-arabinose isomerase activity
F0M21_RS13285	COG3507	Belongs to the glycosyl hydrolase 43 family
F0M21_RS13290	COG1363	Peptidase, m42
F0M21_RS13300	COG3326	Membrane
F0M21_RS13315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0M21_RS13320	COG1346	cytolysis
F0M21_RS13325	COG1380	Effector of murein hydrolase LrgA
F0M21_RS13330	COG3279	Response regulator of the LytR AlgR family
F0M21_RS13335	COG3275	phosphorelay sensor kinase activity
F0M21_RS13340	COG1011	Hydrolase
F0M21_RS13355	COG0398	Pfam SNARE associated Golgi protein
F0M21_RS13360	COG1484	DNA-dependent DNA replication
F0M21_RS13365	COG3611	Membrane attachment protein
F0M21_RS13380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0M21_RS13385	COG1733	regulation of RNA biosynthetic process
F0M21_RS13390	COG2814	Major facilitator Superfamily
F0M21_RS13395	COG0656	L-ascorbic acid biosynthetic process
F0M21_RS13400	COG0237	dephospho-CoA kinase activity
F0M21_RS13405	COG1971	Probably functions as a manganese efflux pump
F0M21_RS13410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0M21_RS13415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0M21_RS13415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0M21_RS13420	COG5002	protein histidine kinase activity
F0M21_RS13425	COG0745	RESPONSE REGULATOR receiver
F0M21_RS13435	COG0538	isocitrate dehydrogenase activity
F0M21_RS13440	COG0372	Belongs to the citrate synthase family
F0M21_RS13460	COG0628	permease
F0M21_RS13465	COG3030	protein affecting phage T7 exclusion by the F plasmid
F0M21_RS13470	COG0469	pyruvate kinase activity
F0M21_RS13490	COG0281	malic enzyme
F0M21_RS13495	COG0587	DNA-directed DNA polymerase activity
F0M21_RS13515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F0M21_RS13525	COG4109	DRTGG domain
F0M21_RS13535	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS13550	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0M21_RS13560	COG0827	DNA restriction-modification system
F0M21_RS13565	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F0M21_RS13570	COG3874	Sporulation protein YtfJ
F0M21_RS13580	COG1714	RDD family
F0M21_RS13585	COG0616	signal peptide processing
F0M21_RS13590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0M21_RS13595	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F0M21_RS13600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M21_RS13615	COG1104	cysteine desulfurase activity
F0M21_RS13620	COG1114	Component of the transport system for branched-chain amino acids
F0M21_RS13630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F0M21_RS13635	COG1309	transcriptional regulator
F0M21_RS13640	COG1956	GAF domain-containing protein
F0M21_RS13645	COG2203	Gaf domain
F0M21_RS13645	COG2199	diguanylate cyclase activity
F0M21_RS13660	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS13665	COG4282	regulation of fungal-type cell wall biogenesis
F0M21_RS13695	COG1595	DNA-templated transcription, initiation
F0M21_RS13720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0M21_RS13720	COG1017	nitric oxide dioxygenase activity
F0M21_RS13735	COG0693	protein deglycase activity
F0M21_RS13750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0M21_RS13755	COG1378	Sugar-specific transcriptional regulator TrmB
F0M21_RS13775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0M21_RS13780	COG0454	-acetyltransferase
F0M21_RS13785	COG0517	IMP dehydrogenase activity
F0M21_RS13790	COG0123	including yeast histone deacetylase and acetoin utilization protein
F0M21_RS13795	COG1360	Flagellar Motor Protein
F0M21_RS13800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F0M21_RS13805	COG1609	Transcriptional regulator
F0M21_RS13810	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
F0M21_RS13810	COG1605	Chorismate mutase
F0M21_RS13815	COG3118	belongs to the thioredoxin family
F0M21_RS13820	COG4980	gas vesicle protein
F0M21_RS13825	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
F0M21_RS13835	COG1674	ftsk spoiiie
F0M21_RS13840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0M21_RS13850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS13860	COG1363	Peptidase, m42
F0M21_RS13865	COG5584	Small secreted protein
F0M21_RS13870	COG0281	malic enzyme
F0M21_RS13875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0M21_RS13890	COG0510	thiamine kinase activity
F0M21_RS13895	COG1597	lipid kinase activity
F0M21_RS13905	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F0M21_RS13910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0M21_RS13915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M21_RS13920	COG2252	PERMEase
F0M21_RS13925	COG4473	ABC transporter
F0M21_RS13930	COG1131	(ABC) transporter
F0M21_RS13935	COG1349	DNA-binding transcription factor activity
F0M21_RS13940	COG1187	pseudouridine synthase activity
F0M21_RS13945	COG2244	polysaccharide biosynthetic process
F0M21_RS13950	COG2081	HI0933 family
F0M21_RS13955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F0M21_RS13965	COG1609	Transcriptional regulator
F0M21_RS13970	COG1653	transport
F0M21_RS13975	COG1175	transmembrane transport
F0M21_RS13980	COG0395	ABC-type sugar transport system, permease component
F0M21_RS13985	COG1486	melibiose metabolic process
F0M21_RS13995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0M21_RS14010	COG1366	Belongs to the anti-sigma-factor antagonist family
F0M21_RS14010	COG2202	Pas domain
F0M21_RS14015	COG2814	Major facilitator Superfamily
F0M21_RS14020	COG5522	Integral membrane protein (intg_mem_TP0381)
F0M21_RS14025	COG0577	efflux transmembrane transporter activity
F0M21_RS14030	COG1136	(ABC) transporter
F0M21_RS14035	COG2205	protein histidine kinase activity
F0M21_RS14040	COG0745	RESPONSE REGULATOR receiver
F0M21_RS14045	COG0577	efflux transmembrane transporter activity
F0M21_RS14050	COG1136	(ABC) transporter
F0M21_RS14070	COG1131	(ABC) transporter
F0M21_RS14075	COG1725	Transcriptional regulator
F0M21_RS14090	COG0640	Transcriptional regulator
F0M21_RS14115	COG0477	Major facilitator Superfamily
F0M21_RS14120	COG1242	4 iron, 4 sulfur cluster binding
F0M21_RS14125	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
F0M21_RS14135	COG0584	glycerophosphoryl diester phosphodiesterase
F0M21_RS14145	COG2267	carboxylic ester hydrolase activity
F0M21_RS14150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F0M21_RS14155	COG1113	amino acid transport
F0M21_RS14160	COG0367	asparagine synthase
F0M21_RS14180	COG1506	peptidase
F0M21_RS14185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F0M21_RS14190	COG1116	anion transmembrane transporter activity
F0M21_RS14195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0M21_RS14200	COG0494	nUDIX hydrolase
F0M21_RS14205	COG4824	toxin secretion phage lysis holin
F0M21_RS14210	COG0783	Belongs to the Dps family
F0M21_RS14235	COG0288	reversible hydration of carbon dioxide
F0M21_RS14245	COG1271	oxidase subunit
F0M21_RS14250	COG1294	oxidase, subunit
F0M21_RS14260	COG4948	Mandelate Racemase Muconate Lactonizing
F0M21_RS14270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F0M21_RS14275	COG0596	Alpha beta hydrolase
F0M21_RS14285	COG1169	isochorismate synthase
F0M21_RS14290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0M21_RS14295	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F0M21_RS14420	COG3859	Proton-coupled thiamine transporter YuaJ
F0M21_RS14425	COG2268	Band 7 protein
F0M21_RS14430	COG1585	Membrane protein implicated in regulation of membrane protease activity
F0M21_RS14435	COG2318	DinB family
F0M21_RS14445	COG1454	alcohol dehydrogenase
F0M21_RS14450	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS14455	COG1510	regulation of RNA biosynthetic process
F0M21_RS14465	COG0569	domain protein
F0M21_RS14470	COG1705	Flagellar rod assembly protein muramidase FlgJ
F0M21_RS14475	COG1017	nitric oxide dioxygenase activity
F0M21_RS14475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0M21_RS14500	COG0628	permease
F0M21_RS14505	COG0673	inositol 2-dehydrogenase activity
F0M21_RS14510	COG0693	protein deglycase activity
F0M21_RS14515	COG0840	transmembrane signaling receptor activity
F0M21_RS14520	COG0840	transmembrane signaling receptor activity
F0M21_RS14525	COG0840	transmembrane signaling receptor activity
F0M21_RS14530	COG0840	transmembrane signaling receptor activity
F0M21_RS14545	COG2070	2-Nitropropane dioxygenase
F0M21_RS14550	COG0432	Pfam Uncharacterised protein family UPF0047
F0M21_RS14555	COG0366	Alpha amylase catalytic
F0M21_RS14560	COG1253	flavin adenine dinucleotide binding
F0M21_RS14565	COG2738	Putative neutral zinc metallopeptidase
F0M21_RS14580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0M21_RS14610	COG1335	isochorismatase
F0M21_RS14615	COG1979	alcohol dehydrogenase
F0M21_RS14620	COG1979	alcohol dehydrogenase
F0M21_RS14625	COG2155	Conserved Protein
F0M21_RS14630	COG1098	S1 RNA binding domain
F0M21_RS14635	COG0436	Aminotransferase
F0M21_RS14640	COG1522	sequence-specific DNA binding
F0M21_RS14645	COG2267	carboxylic ester hydrolase activity
F0M21_RS14655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F0M21_RS14660	COG2205	protein histidine kinase activity
F0M21_RS14670	COG5018	Exonuclease
F0M21_RS14675	COG2814	Major facilitator Superfamily
F0M21_RS14680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0M21_RS14685	COG3011	Protein conserved in bacteria
F0M21_RS14695	COG3290	protein histidine kinase activity
F0M21_RS14700	COG4565	transcriptional regulatory protein
F0M21_RS14705	COG1744	ABC transporter substrate-binding protein PnrA-like
F0M21_RS14710	COG3845	ABC transporter
F0M21_RS14715	COG4603	Belongs to the binding-protein-dependent transport system permease family
F0M21_RS14720	COG1079	Belongs to the binding-protein-dependent transport system permease family
F0M21_RS14730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0M21_RS14730	COG2111	Na H antiporter
F0M21_RS14735	COG2111	Na H antiporter
F0M21_RS14740	COG1006	Multisubunit Na H antiporter MnhC subunit
F0M21_RS14745	COG0651	ATP synthesis coupled electron transport
F0M21_RS14750	COG1863	multisubunit Na H antiporter MnhE subunit
F0M21_RS14755	COG2212	antiporter activity
F0M21_RS14760	COG1320	monovalent cation:proton antiporter activity
F0M21_RS14765	COG2050	protein possibly involved in aromatic compounds catabolism
F0M21_RS14770	COG2197	response regulator
F0M21_RS14775	COG4585	Histidine kinase
F0M21_RS14805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
F0M21_RS14810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0M21_RS14815	COG1335	isochorismatase
F0M21_RS14820	COG5506	Protein of unknown function (DUF1694)
F0M21_RS14835	COG0628	permease
F0M21_RS14845	COG1418	mRNA catabolic process
F0M21_RS14850	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS14860	COG1511	domain protein
F0M21_RS14865	COG0433	COG0433 Predicted ATPase
F0M21_RS14865	COG1674	ftsk spoiiie
F0M21_RS14870	COG4499	WXG100 protein secretion system (Wss), protein YukC
F0M21_RS14875	COG5417	Belongs to the EsaB family
F0M21_RS14880	COG4842	Belongs to the WXG100 family
F0M21_RS14885	COG2508	Transcriptional regulator
F0M21_RS14885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
F0M21_RS14890	COG0686	Belongs to the AlaDH PNT family
F0M21_RS14895	COG5634	Uncharacterized conserved protein (DUF2278)
F0M21_RS14900	COG3251	PFAM MbtH domain protein
F0M21_RS14905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0M21_RS14910	COG1535	isochorismatase
F0M21_RS14910	COG3433	isochorismatase activity
F0M21_RS14915	COG1021	2,3-dihydroxybenzoate-AMP ligase
F0M21_RS14920	COG1169	isochorismate synthase
F0M21_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS14930	COG2819	hydrolase of the alpha beta superfamily
F0M21_RS14935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F0M21_RS14940	COG1268	BioY protein
F0M21_RS14945	COG2056	Na+-H+ antiporter family
F0M21_RS14955	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
F0M21_RS14960	COG3584	3D domain protein
F0M21_RS14975	COG1252	NADH dehydrogenase
F0M21_RS15005	COG1131	(ABC) transporter
F0M21_RS15025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0M21_RS15030	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F0M21_RS15035	COG0316	Belongs to the HesB IscA family
F0M21_RS15045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0M21_RS15055	COG1252	NADH dehydrogenase
F0M21_RS15060	COG4837	Protein of unknown function (DUF1462)
F0M21_RS15065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F0M21_RS15070	COG4946	Tricorn protease homolog
F0M21_RS15070	COG0823	Involved in the tonB-independent uptake of proteins
F0M21_RS15070	COG1506	peptidase
F0M21_RS15080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F0M21_RS15085	COG0460	homoserine dehydrogenase
F0M21_RS15090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F0M21_RS15095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F0M21_RS15100	COG0647	UMP catabolic process
F0M21_RS15105	COG2445	Protein of unknown function DUF86
F0M21_RS15110	COG4470	Protein conserved in bacteria
F0M21_RS15125	COG0739	heme binding
F0M21_RS15135	COG0737	Belongs to the 5'-nucleotidase family
F0M21_RS15140	COG0730	response to heat
F0M21_RS15145	COG1801	Protein of unknown function DUF72
F0M21_RS15160	COG2508	Transcriptional regulator
F0M21_RS15170	COG2814	Major facilitator Superfamily
F0M21_RS15175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F0M21_RS15180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0M21_RS15185	COG2356	endonuclease I
F0M21_RS15190	COG3842	ATPase activity
F0M21_RS15195	COG2188	Transcriptional regulator
F0M21_RS15200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M21_RS15205	COG0395	ABC-type sugar transport system, permease component
F0M21_RS15210	COG1175	transmembrane transport
F0M21_RS15215	COG1653	transport
F0M21_RS15220	COG2222	sugar isomerase
F0M21_RS15225	COG0789	Transcriptional regulator
F0M21_RS15240	COG0322	excinuclease ABC activity
F0M21_RS15245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0M21_RS15250	COG2226	methyltransferase
F0M21_RS15265	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS15270	COG0719	Fe-S assembly protein
F0M21_RS15275	COG0822	iron-sulfur transferase activity
F0M21_RS15280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0M21_RS15285	COG0719	Fe-S assembly protein
F0M21_RS15290	COG0396	ATPase activity
F0M21_RS15300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0M21_RS15305	COG1464	Belongs to the NlpA lipoprotein family
F0M21_RS15310	COG2011	ABC-type metal ion transport system permease component
F0M21_RS15315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0M21_RS15325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0M21_RS15330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
F0M21_RS15345	COG1393	Belongs to the ArsC family
F0M21_RS15350	COG1960	acyl-CoA dehydrogenase activity
F0M21_RS15355	COG0183	Belongs to the thiolase family
F0M21_RS15360	COG1024	Enoyl-CoA hydratase
F0M21_RS15360	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0M21_RS15380	COG5577	PFAM Coat F domain
F0M21_RS15385	COG1846	Transcriptional regulator
F0M21_RS15390	COG0477	Major facilitator Superfamily
F0M21_RS15395	COG1942	4-Oxalocrotonate Tautomerase
F0M21_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS15405	COG0583	DNA-binding transcription factor activity
F0M21_RS15420	COG0583	DNA-binding transcription factor activity
F0M21_RS15440	COG1120	ATPase activity
F0M21_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS15460	COG0783	Belongs to the Dps family
F0M21_RS15465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0M21_RS15475	COG0745	RESPONSE REGULATOR receiver
F0M21_RS15480	COG2205	protein histidine kinase activity
F0M21_RS15480	COG2770	Histidine kinase
F0M21_RS15490	COG1309	transcriptional regulator
F0M21_RS15495	COG0114	fumarate hydratase activity
F0M21_RS15505	COG0697	spore germination
F0M21_RS15510	COG0814	amino acid
F0M21_RS15520	COG2197	response regulator
F0M21_RS15525	COG4585	Histidine kinase
F0M21_RS15530	COG4758	membrane
F0M21_RS15535	COG3595	metallopeptidase activity
F0M21_RS15540	COG1842	Phage shock protein A
F0M21_RS15545	COG4758	membrane
F0M21_RS15550	COG2814	Major facilitator Superfamily
F0M21_RS15555	COG2096	Adenosyltransferase
F0M21_RS15560	COG1120	ATPase activity
F0M21_RS15565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS15570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0M21_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS15580	COG3386	PFAM SMP-30 Gluconolaconase
F0M21_RS15585	COG2205	protein histidine kinase activity
F0M21_RS15590	COG0745	RESPONSE REGULATOR receiver
F0M21_RS15600	COG1191	sigma factor activity
F0M21_RS15610	COG2140	Oxalate decarboxylase
F0M21_RS15620	COG1120	ATPase activity
F0M21_RS15625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS15630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS15635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0M21_RS15640	COG0531	amino acid
F0M21_RS15655	COG1988	membrane-bound metal-dependent
F0M21_RS15660	COG1368	sulfuric ester hydrolase activity
F0M21_RS15665	COG1910	domain protein
F0M21_RS15670	COG0725	ABC transporter, periplasmic molybdate-binding protein
F0M21_RS15675	COG4149	molybdate abc transporter
F0M21_RS15680	COG2197	response regulator
F0M21_RS15685	COG3850	Histidine kinase
F0M21_RS15690	COG1131	(ABC) transporter
F0M21_RS15700	COG0842	Transport permease protein
F0M21_RS15705	COG0656	L-ascorbic acid biosynthetic process
F0M21_RS15730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0M21_RS15735	COG3973	AAA domain
F0M21_RS15740	COG2860	membrane
F0M21_RS15750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0M21_RS15755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0M21_RS15760	COG2217	Heavy metal translocating P-type atpase
F0M21_RS15765	COG2217	Heavy metal translocating P-type atpase
F0M21_RS15770	COG2608	mercury ion transmembrane transporter activity
F0M21_RS15775	COG1937	Protein conserved in bacteria
F0M21_RS15780	COG0673	inositol 2-dehydrogenase activity
F0M21_RS15800	COG2814	Major facilitator Superfamily
F0M21_RS15815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS15820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0M21_RS15825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS15830	COG1126	abc transporter atp-binding protein
F0M21_RS15835	COG0765	amino acid transport
F0M21_RS15840	COG0765	amino acid transport
F0M21_RS15845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0M21_RS15855	COG0454	-acetyltransferase
F0M21_RS15860	COG0583	DNA-binding transcription factor activity
F0M21_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS15870	COG2732	(Barnase) inhibitor
F0M21_RS15885	COG0557	exoribonuclease II activity
F0M21_RS15890	COG1647	Serine aminopeptidase, S33
F0M21_RS15895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0M21_RS15900	COG1476	TRANSCRIPTIONal
F0M21_RS15905	COG1396	sequence-specific DNA binding
F0M21_RS15910	COG1396	sequence-specific DNA binding
F0M21_RS15915	COG1733	regulation of RNA biosynthetic process
F0M21_RS15940	COG1131	(ABC) transporter
F0M21_RS15945	COG1174	glycine betaine transport
F0M21_RS15950	COG1732	Glycine betaine
F0M21_RS15955	COG1174	glycine betaine transport
F0M21_RS15960	COG1125	glycine betaine transport
F0M21_RS15960	COG0517	IMP dehydrogenase activity
F0M21_RS15965	COG1510	regulation of RNA biosynthetic process
F0M21_RS15970	COG1174	glycine betaine transport
F0M21_RS15975	COG1732	Glycine betaine
F0M21_RS15980	COG1174	glycine betaine transport
F0M21_RS15985	COG1125	glycine betaine transport
F0M21_RS15985	COG0517	IMP dehydrogenase activity
F0M21_RS15990	COG1510	regulation of RNA biosynthetic process
F0M21_RS15995	COG2095	MarC family integral membrane protein
F0M21_RS16000	COG3064	Membrane
F0M21_RS16005	COG4640	response to antibiotic
F0M21_RS16010	COG0456	acetyltransferase
F0M21_RS16025	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F0M21_RS16040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0M21_RS16045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0M21_RS16050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0M21_RS16060	COG2234	aminopeptidase activity
F0M21_RS16080	COG0126	phosphoglycerate kinase activity
F0M21_RS16090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0M21_RS16095	COG2390	Transcriptional regulator
F0M21_RS16100	COG2814	Major facilitator Superfamily
F0M21_RS16105	COG1609	Transcriptional regulator
F0M21_RS16110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS16120	COG0583	DNA-binding transcription factor activity
F0M21_RS16125	COG0697	spore germination
F0M21_RS16130	COG1113	amino acid transport
F0M21_RS16140	COG1609	Transcriptional regulator
F0M21_RS16150	COG0561	phosphatase activity
F0M21_RS16155	COG1737	Transcriptional regulator
F0M21_RS16160	COG1070	Carbohydrate kinase
F0M21_RS16185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0M21_RS16190	COG2186	Transcriptional regulator
F0M21_RS16195	COG1620	l-lactate permease
F0M21_RS16200	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0M21_RS16210	COG5039	Polysaccharide pyruvyl transferase
F0M21_RS16215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0M21_RS16220	COG0110	maltose O-acetyltransferase activity
F0M21_RS16225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F0M21_RS16230	COG2244	polysaccharide biosynthetic process
F0M21_RS16235	COG1216	Glycosyl transferase, family 2
F0M21_RS16240	COG5039	Polysaccharide pyruvyl transferase
F0M21_RS16245	COG1216	Glycosyl transferase, family 2
F0M21_RS16255	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS16260	COG1215	transferase activity, transferring glycosyl groups
F0M21_RS16265	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS16270	COG1086	Polysaccharide biosynthesis protein
F0M21_RS16275	COG0489	protein tyrosine kinase activity
F0M21_RS16280	COG3944	biosynthesis protein
F0M21_RS16285	COG1396	sequence-specific DNA binding
F0M21_RS16290	COG2272	Belongs to the type-B carboxylesterase lipase family
F0M21_RS16295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F0M21_RS16300	COG2364	Membrane
F0M21_RS16305	COG0456	acetyltransferase
F0M21_RS16310	COG3479	Phenolic acid decarboxylase
F0M21_RS16360	COG2223	nitrite transmembrane transporter activity
F0M21_RS16365	COG1609	Transcriptional regulator
F0M21_RS16375	COG0583	DNA-binding transcription factor activity
F0M21_RS16380	COG2828	Protein conserved in bacteria
F0M21_RS16385	COG2814	Major facilitator Superfamily
F0M21_RS16385	COG0477	Major facilitator Superfamily
F0M21_RS16390	COG1611	Belongs to the LOG family
F0M21_RS16395	COG1694	Mazg nucleotide pyrophosphohydrolase
F0M21_RS16400	COG0659	secondary active sulfate transmembrane transporter activity
F0M21_RS16405	COG0288	reversible hydration of carbon dioxide
F0M21_RS16415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0M21_RS16420	COG4290	ribonuclease
F0M21_RS16425	COG2162	N-hydroxyarylamine O-acetyltransferase activity
F0M21_RS16430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS16440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F0M21_RS16450	COG1051	belongs to the nudix hydrolase family
F0M21_RS16455	COG0492	ferredoxin-NADP+ reductase activity
F0M21_RS16460	COG0791	NLP P60 protein
F0M21_RS16460	COG3883	PFAM NLP P60 protein
F0M21_RS16465	COG0457	Tetratricopeptide repeat
F0M21_RS16470	COG5002	protein histidine kinase activity
F0M21_RS16475	COG0745	RESPONSE REGULATOR receiver
F0M21_RS16480	COG1132	(ABC) transporter
F0M21_RS16485	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0M21_RS16485	COG0140	phosphoribosyl-ATP diphosphatase activity
F0M21_RS16510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F0M21_RS16525	COG4990	cell redox homeostasis
F0M21_RS16530	COG0110	maltose O-acetyltransferase activity
F0M21_RS16550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F0M21_RS16560	COG2188	Transcriptional regulator
F0M21_RS16565	COG1309	transcriptional regulator
F0M21_RS16570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0M21_RS16575	COG1950	PFAM Membrane protein of
F0M21_RS16580	COG1983	PspC domain protein
F0M21_RS16585	COG3595	metallopeptidase activity
F0M21_RS16600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0M21_RS16610	COG4897	Protein conserved in bacteria
F0M21_RS16615	COG0574	Belongs to the PEP-utilizing enzyme family
F0M21_RS16615	COG3848	Pyruvate phosphate dikinase
F0M21_RS16620	COG1309	transcriptional regulator
F0M21_RS16625	COG2814	Major facilitator Superfamily
F0M21_RS16630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0M21_RS16640	COG3409	Peptidoglycan-binding domain 1 protein
F0M21_RS16640	COG0793	Belongs to the peptidase S41A family
F0M21_RS16645	COG3420	alginic acid biosynthetic process
F0M21_RS16650	COG2177	Part of the ABC transporter FtsEX involved in
F0M21_RS16655	COG2884	Cell division ATP-binding protein ftsE
F0M21_RS16660	COG2010	Cytochrome c
F0M21_RS16665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS16680	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F0M21_RS16695	COG1516	flagellar protein fliS
F0M21_RS16700	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
F0M21_RS16705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F0M21_RS16725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F0M21_RS16730	COG1256	bacterial-type flagellum assembly
F0M21_RS16730	COG4786	Flagellar basal body rod
F0M21_RS16735	COG3418	PFAM FlgN family protein
F0M21_RS16740	COG2747	anti-sigma28 factor FlgM
F0M21_RS16750	COG1040	competence protein
F0M21_RS16760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
F0M21_RS16765	COG1307	EDD domain protein, DegV family
F0M21_RS16770	COG2197	response regulator
F0M21_RS16775	COG4585	Histidine kinase
F0M21_RS16780	COG1739	Uncharacterized protein family UPF0029
F0M21_RS16785	COG1316	TRANSCRIPTIONal
F0M21_RS16790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0M21_RS16795	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS16800	COG1215	transferase activity, transferring glycosyl groups
F0M21_RS16805	COG3206	protein involved in exopolysaccharide biosynthesis
F0M21_RS16810	COG3307	-O-antigen
F0M21_RS16815	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F0M21_RS16820	COG0297	glycogen (starch) synthase activity
F0M21_RS16820	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS16825	COG2244	polysaccharide biosynthetic process
F0M21_RS16835	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0M21_RS16835	COG2247	cell wall binding repeat
F0M21_RS16840	COG2385	sporulation resulting in formation of a cellular spore
F0M21_RS16840	COG2247	cell wall binding repeat
F0M21_RS16850	COG1316	TRANSCRIPTIONal
F0M21_RS16855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F0M21_RS16860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0M21_RS16865	COG1134	teichoic acid transport
F0M21_RS16870	COG1682	transport, permease protein
F0M21_RS16875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F0M21_RS16885	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0M21_RS16890	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
F0M21_RS16895	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F0M21_RS16900	COG4193	domain, Protein
F0M21_RS16905	COG1482	cell wall glycoprotein biosynthetic process
F0M21_RS16910	COG0697	spore germination
F0M21_RS16915	COG0814	amino acid
F0M21_RS16925	COG1215	transferase activity, transferring glycosyl groups
F0M21_RS16930	COG2814	Major facilitator Superfamily
F0M21_RS16935	COG1316	TRANSCRIPTIONal
F0M21_RS16940	COG0561	phosphatase activity
F0M21_RS16945	COG2433	Pfam Transposase IS66
F0M21_RS16950	COG0791	NLP P60 protein
F0M21_RS16960	COG2843	Capsule synthesis protein
F0M21_RS16970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F0M21_RS16980	COG0814	amino acid
F0M21_RS16990	COG1609	Transcriptional regulator
F0M21_RS16995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0M21_RS17005	COG1129	ABC transporter
F0M21_RS17010	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0M21_RS17015	COG1879	ABC-type sugar transport system periplasmic component
F0M21_RS17020	COG3103	Sh3 type 3 domain protein
F0M21_RS17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0M21_RS17030	COG3527	Alpha-acetolactate decarboxylase
F0M21_RS17035	COG0028	Belongs to the TPP enzyme family
F0M21_RS17040	COG0583	DNA-binding transcription factor activity
F0M21_RS17045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F0M21_RS17060	COG5337	Spore coat protein CotH
F0M21_RS17070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F0M21_RS17080	COG0405	Gamma-glutamyltransferase
F0M21_RS17085	COG1522	sequence-specific DNA binding
F0M21_RS17090	COG2059	Chromate
F0M21_RS17095	COG2059	Chromate
F0M21_RS17150	COG5444	nuclease activity
F0M21_RS17165	COG3878	Protein conserved in bacteria
F0M21_RS17170	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F0M21_RS17175	COG4464	protein tyrosine phosphatase activity
F0M21_RS17180	COG0489	protein tyrosine kinase activity
F0M21_RS17185	COG3944	biosynthesis protein
F0M21_RS17200	COG4715	Zinc finger, swim domain protein
F0M21_RS17205	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0M21_RS17210	COG0561	phosphatase activity
F0M21_RS17215	COG1349	DNA-binding transcription factor activity
F0M21_RS17220	COG0629	single-stranded DNA binding
F0M21_RS17245	COG0457	Tetratricopeptide repeat
F0M21_RS17250	COG4786	Flagellar basal body rod
F0M21_RS17255	COG4786	Flagellar basal body rod
F0M21_RS17260	COG1077	Cell shape determining protein MreB Mrl
F0M21_RS17265	COG1609	Transcriptional regulator
F0M21_RS17270	COG1846	Transcriptional regulator
F0M21_RS17275	COG2814	Major facilitator Superfamily
F0M21_RS17280	COG1953	Uracil, thiamine, allantoin
F0M21_RS17285	COG0477	Major facilitator Superfamily
F0M21_RS17290	COG1335	isochorismatase
F0M21_RS17295	COG0004	ammonium transporteR
F0M21_RS17300	COG0347	Belongs to the P(II) protein family
F0M21_RS17305	COG0772	Belongs to the SEDS family
F0M21_RS17310	COG0671	phosphoesterase, PA-phosphatase related
F0M21_RS17320	COG0739	heme binding
F0M21_RS17325	COG1247	-acetyltransferase
F0M21_RS17340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0M21_RS17355	COG0726	polysaccharide deacetylase
F0M21_RS17365	COG1959	2 iron, 2 sulfur cluster binding
F0M21_RS17380	COG0831	urea catabolic process
F0M21_RS17385	COG3237	CsbD-like
F0M21_RS17390	COG1994	Peptidase M50
F0M21_RS17395	COG0457	Tetratricopeptide repeat
F0M21_RS17405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F0M21_RS17410	COG2304	oxidoreductase activity
F0M21_RS17415	COG2304	oxidoreductase activity
F0M21_RS17425	COG2385	sporulation resulting in formation of a cellular spore
F0M21_RS17430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0M21_RS17440	COG4836	Membrane
F0M21_RS17510	COG0698	ribose 5-phosphate isomerase
F0M21_RS17515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F0M21_RS17525	COG0009	L-threonylcarbamoyladenylate synthase
F0M21_RS17530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F0M21_RS17550	COG2890	protein-(glutamine-N5) methyltransferase activity
F0M21_RS17555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0M21_RS17560	COG0346	lactoylglutathione lyase activity
F0M21_RS17565	COG0789	Transcriptional regulator
F0M21_RS17570	COG0679	Auxin Efflux Carrier
F0M21_RS17575	COG0281	malic enzyme
F0M21_RS17590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F0M21_RS17595	COG1494	fructose-1,6-bisphosphatase
F0M21_RS17600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0M21_RS17610	COG0191	fructose-bisphosphate aldolase activity
F0M21_RS17615	COG2204	response regulator
F0M21_RS17620	COG4821	SIS domain
F0M21_RS17635	COG2181	nitrate reductase activity
F0M21_RS17635	COG0247	lactate metabolic process
F0M21_RS17640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0M21_RS17655	COG1132	(ABC) transporter
F0M21_RS17660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0M21_RS17670	COG2181	nitrate reductase activity
F0M21_RS17675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
F0M21_RS17680	COG1140	nitrate reductase beta subunit
F0M21_RS17685	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
F0M21_RS17690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0M21_RS17700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0M21_RS17705	COG2223	nitrite transmembrane transporter activity
F0M21_RS17715	COG4506	Protein conserved in bacteria
F0M21_RS17725	COG3391	amine dehydrogenase activity
F0M21_RS17730	COG3391	amine dehydrogenase activity
F0M21_RS17740	COG0457	Tetratricopeptide repeat
F0M21_RS17785	COG0010	Belongs to the arginase family
F0M21_RS17790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0M21_RS17795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0M21_RS17810	COG1994	Peptidase M50
F0M21_RS17815	COG1942	4-Oxalocrotonate Tautomerase
F0M21_RS17820	COG1846	Transcriptional regulator
F0M21_RS17830	COG0531	amino acid
F0M21_RS17835	COG3465	dGTPase activity
F0M21_RS17840	COG1078	dGTPase activity
F0M21_RS17855	COG1695	Transcriptional regulator
F0M21_RS17865	COG1131	(ABC) transporter
F0M21_RS17870	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
F0M21_RS17900	COG0583	DNA-binding transcription factor activity
F0M21_RS17905	COG2855	membrane
F0M21_RS17910	COG0280	phosphate acetyltransferase
F0M21_RS17920	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS17925	COG0436	Aminotransferase
F0M21_RS17955	COG2814	Major facilitator Superfamily
F0M21_RS17960	COG2814	Major facilitator Superfamily
F0M21_RS17965	COG0833	amino acid
F0M21_RS17970	COG4187	Peptidase family M20/M25/M40
F0M21_RS17975	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS17980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F0M21_RS17985	COG2205	protein histidine kinase activity
F0M21_RS17990	COG0745	RESPONSE REGULATOR receiver
F0M21_RS18005	COG1131	(ABC) transporter
F0M21_RS18010	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F0M21_RS18015	COG1091	dTDP-4-dehydrorhamnose reductase activity
F0M21_RS18020	COG1088	dTDP-glucose 4,6-dehydratase activity
F0M21_RS18025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F0M21_RS18030	COG3980	spore coat polysaccharide biosynthesis protein
F0M21_RS18035	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
F0M21_RS18040	COG2089	acid synthase
F0M21_RS18045	COG0456	acetyltransferase
F0M21_RS18050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0M21_RS18055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
F0M21_RS18060	COG0463	Glycosyl transferase, family 2
F0M21_RS18070	COG2363	Small membrane protein
F0M21_RS18075	COG2233	PERMEase
F0M21_RS18090	COG1216	Glycosyl transferase, family 2
F0M21_RS18105	COG1695	Transcriptional regulator
F0M21_RS18110	COG0351	phosphomethylpyrimidine kinase
F0M21_RS18120	COG1621	beta-fructofuranosidase activity
F0M21_RS18125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS18125	COG1263	PTS System
F0M21_RS18130	COG3711	transcriptional antiterminator
F0M21_RS18140	COG1404	Belongs to the peptidase S8 family
F0M21_RS18145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0M21_RS18155	COG0778	Nitroreductase
F0M21_RS18160	COG0772	Belongs to the SEDS family
F0M21_RS18165	COG0454	-acetyltransferase
F0M21_RS18185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0M21_RS18190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0M21_RS18195	COG2261	transglycosylase associated protein
F0M21_RS18200	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
F0M21_RS18205	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F0M21_RS18210	COG2246	polysaccharide biosynthetic process
F0M21_RS18215	COG1309	transcriptional regulator
F0M21_RS18235	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F0M21_RS18240	COG2837	iron assimilation
F0M21_RS18245	COG2822	iron ion transport
F0M21_RS18260	COG0583	DNA-binding transcription factor activity
F0M21_RS18270	COG1346	cytolysis
F0M21_RS18275	COG4895	conserved protein (DUF2196)
F0M21_RS18280	COG0789	Transcriptional regulator
F0M21_RS18285	COG5504	Zn-dependent protease
F0M21_RS18290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0M21_RS18295	COG0346	lactoylglutathione lyase activity
F0M21_RS18300	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS18305	COG1404	Belongs to the peptidase S8 family
F0M21_RS18310	COG1442	glycosyl transferase family 8
F0M21_RS18315	COG2357	RelA SpoT domain protein
F0M21_RS18320	COG1575	Belongs to the MenA family. Type 1 subfamily
F0M21_RS18345	COG1696	Membrane protein involved in D-alanine export
F0M21_RS18355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
F0M21_RS18360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0M21_RS18365	COG1486	melibiose metabolic process
F0M21_RS18370	COG1447	Phosphotransferase system cellobiose-specific component IIA
F0M21_RS18375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS18380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS18385	COG3711	transcriptional antiterminator
F0M21_RS18385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0M21_RS18400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0M21_RS18415	COG0640	Transcriptional regulator
F0M21_RS18420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F0M21_RS18425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS18430	COG1447	Phosphotransferase system cellobiose-specific component IIA
F0M21_RS18435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0M21_RS18440	COG2723	6-phospho-beta-galactosidase activity
F0M21_RS18445	COG1940	carbohydrate kinase activity
F0M21_RS18450	COG1482	cell wall glycoprotein biosynthetic process
F0M21_RS18460	COG0753	catalase activity
F0M21_RS18465	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
F0M21_RS18470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F0M21_RS18475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0M21_RS18480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0M21_RS18485	COG4988	ABC transporter
F0M21_RS18490	COG1294	oxidase, subunit
F0M21_RS18495	COG1271	oxidase subunit
F0M21_RS18500	COG3493	citrate carrier protein
F0M21_RS18505	COG0726	polysaccharide deacetylase
F0M21_RS18510	COG3842	ATPase activity
F0M21_RS18515	COG2508	Transcriptional regulator
F0M21_RS18520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS18530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0M21_RS18540	COG4894	glucomannan catabolic process
F0M21_RS18545	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F0M21_RS18550	COG0500	methyltransferase
F0M21_RS18555	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0M21_RS18570	COG0693	protein deglycase activity
F0M21_RS18570	COG0753	catalase activity
F0M21_RS18575	COG2851	Citrate transporter
F0M21_RS18580	COG2273	Hydrolase Family 16
F0M21_RS18585	COG3711	transcriptional antiterminator
F0M21_RS18590	COG2270	Major facilitator Superfamily
F0M21_RS18595	COG0513	Belongs to the DEAD box helicase family
F0M21_RS18650	COG0697	spore germination
F0M21_RS18655	COG0589	response to stress
F0M21_RS18660	COG2723	6-phospho-beta-galactosidase activity
F0M21_RS18665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0M21_RS18665	COG2190	(PTS) system
F0M21_RS18665	COG1263	PTS System
F0M21_RS18675	COG0494	nUDIX hydrolase
F0M21_RS18680	COG3507	Belongs to the glycosyl hydrolase 43 family
F0M21_RS18705	COG0010	Belongs to the arginase family
F0M21_RS18710	COG0833	amino acid
F0M21_RS18715	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F0M21_RS18720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0M21_RS18730	COG2390	Transcriptional regulator
F0M21_RS18735	COG0561	phosphatase activity
F0M21_RS18765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0M21_RS18775	COG5294	Protein conserved in bacteria
F0M21_RS18780	COG0577	efflux transmembrane transporter activity
F0M21_RS18785	COG1136	(ABC) transporter
F0M21_RS18790	COG2205	protein histidine kinase activity
F0M21_RS18795	COG0745	RESPONSE REGULATOR receiver
F0M21_RS18800	COG2205	protein histidine kinase activity
F0M21_RS18805	COG0745	RESPONSE REGULATOR receiver
F0M21_RS18835	COG1082	Xylose isomerase domain protein TIM barrel
F0M21_RS18845	COG2814	Major facilitator Superfamily
F0M21_RS18875	COG1349	DNA-binding transcription factor activity
F0M21_RS18880	COG0667	Aldo Keto reductase
F0M21_RS18885	COG2814	Major facilitator Superfamily
F0M21_RS18900	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS18905	COG2197	response regulator
F0M21_RS18910	COG4585	Histidine kinase
F0M21_RS18915	COG3239	Fatty acid desaturase
F0M21_RS18925	COG1309	transcriptional regulator
F0M21_RS18930	COG1012	belongs to the aldehyde dehydrogenase family
F0M21_RS18935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0M21_RS18945	COG0640	Transcriptional regulator
F0M21_RS18950	COG2814	Major facilitator Superfamily
F0M21_RS18955	COG1714	RDD family
F0M21_RS18965	COG0450	alkyl hydroperoxide reductase
F0M21_RS18970	COG3634	alkyl hydroperoxide reductase activity
F0M21_RS18975	COG3177	Filamentation induced by cAMP protein fic
F0M21_RS18980	COG1113	amino acid transport
F0M21_RS18990	COG2080	2 iron, 2 sulfur cluster binding
F0M21_RS19005	COG2068	MobA-Related Protein
F0M21_RS19010	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F0M21_RS19080	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
F0M21_RS19085	COG0667	Aldo Keto reductase
F0M21_RS19090	COG0456	acetyltransferase
F0M21_RS19095	COG0457	Tetratricopeptide repeat
F0M21_RS19100	COG0010	Belongs to the arginase family
F0M21_RS19105	COG0833	amino acid
F0M21_RS19110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0M21_RS19115	COG3829	transcription factor binding
F0M21_RS19125	COG0488	(ABC) transporter
F0M21_RS19140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0M21_RS19145	COG5002	protein histidine kinase activity
F0M21_RS19145	COG3850	Histidine kinase
F0M21_RS19150	COG0745	RESPONSE REGULATOR receiver
F0M21_RS19155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0M21_RS19160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F0M21_RS19165	COG4853	Protein conserved in bacteria
F0M21_RS19170	COG4863	YycH protein
F0M21_RS19175	COG5002	protein histidine kinase activity
F0M21_RS19180	COG0745	RESPONSE REGULATOR receiver
F0M21_RS19215	COG0346	lactoylglutathione lyase activity
F0M21_RS19220	COG0305	Participates in initiation and elongation during chromosome replication
F0M21_RS19240	COG3093	addiction module antidote protein HigA
F0M21_RS19245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0M21_RS19260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0M21_RS19265	COG0438	transferase activity, transferring glycosyl groups
F0M21_RS19285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
F0M21_RS19290	COG4241	membrane
F0M21_RS19300	COG5577	PFAM Coat F domain
F0M21_RS19305	COG1733	regulation of RNA biosynthetic process
F0M21_RS19315	COG0697	spore germination
F0M21_RS19320	COG1621	beta-fructofuranosidase activity
F0M21_RS19325	COG1621	beta-fructofuranosidase activity
F0M21_RS19330	COG1802	Transcriptional regulator
F0M21_RS19335	COG2318	DinB family
F0M21_RS19345	COG0583	DNA-binding transcription factor activity
F0M21_RS19355	COG2814	Major facilitator Superfamily
F0M21_RS19360	COG0583	DNA-binding transcription factor activity
F0M21_RS19370	COG0778	Nitroreductase
F0M21_RS19375	COG1846	Transcriptional regulator
F0M21_RS19380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F0M21_RS19385	COG1846	Transcriptional regulator
F0M21_RS19390	COG2153	protein acetylation
F0M21_RS19400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0M21_RS19405	COG0583	DNA-binding transcription factor activity
F0M21_RS19410	COG1028	Short-chain dehydrogenase reductase Sdr
F0M21_RS19425	COG1331	Highly conserved protein containing a thioredoxin domain
F0M21_RS19445	COG2815	serine threonine protein kinase
F0M21_RS19445	COG0515	serine threonine protein kinase
F0M21_RS19450	COG1331	Highly conserved protein containing a thioredoxin domain
F0M21_RS19455	COG1266	CAAX protease self-immunity
F0M21_RS19460	COG0477	Major facilitator Superfamily
F0M21_RS19460	COG2814	Major facilitator Superfamily
F0M21_RS19465	COG0346	lactoylglutathione lyase activity
F0M21_RS19470	COG1609	Transcriptional regulator
F0M21_RS19475	COG0708	Exodeoxyribonuclease III
F0M21_RS19480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0M21_RS19485	COG2169	Transcriptional regulator
F0M21_RS19495	COG0629	single-stranded DNA binding
F0M21_RS19505	COG0012	GTP binding
F0M21_RS19510	COG0243	molybdopterin cofactor binding
F0M21_RS19515	COG4481	Protein conserved in bacteria
F0M21_RS19520	COG3949	Membrane
F0M21_RS19535	COG1475	DNA binding
F0M21_RS19540	COG1192	Involved in chromosome partitioning
F0M21_RS19565	COG1847	R3H domain protein
F0M21_RS19570	COG0706	membrane insertase activity