locus-tag	class	description
KM843_RS00010	COG0592	DNA-directed DNA polymerase activity
KM843_RS00015	COG2501	S4 domain
KM843_RS00030	COG0187	DNA topoisomerase II activity
KM843_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM843_RS00070	COG0516	GMP reductase activity
KM843_RS00070	COG0517	IMP dehydrogenase activity
KM843_RS00075	COG1686	Belongs to the peptidase S11 family
KM843_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
KM843_RS00105	COG1428	Deoxynucleoside kinase
KM843_RS00110	COG1428	Deoxynucleoside kinase
KM843_RS00115	COG1388	LysM domain
KM843_RS00115	COG3858	chitin binding
KM843_RS00120	COG1335	isochorismatase
KM843_RS00125	COG0590	tRNA wobble adenosine to inosine editing
KM843_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM843_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KM843_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KM843_RS00195	COG3853	Toxic anion resistance protein (TelA)
KM843_RS00200	COG1982	Orn Lys Arg decarboxylase major
KM843_RS00210	COG3870	Protein conserved in bacteria
KM843_RS00215	COG1728	Protein conserved in bacteria
KM843_RS00220	COG0470	DNA polymerase III
KM843_RS00225	COG1774	PSP1 C-terminal conserved region
KM843_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KM843_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KM843_RS00250	COG2002	toxin-antitoxin pair type II binding
KM843_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM843_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM843_RS00260	COG0084	hydrolase, TatD family'
KM843_RS00265	COG3583	domain protein
KM843_RS00265	COG3584	3D domain protein
KM843_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM843_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KM843_RS00285	COG4466	Protein conserved in bacteria
KM843_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KM843_RS00305	COG0251	oxidation-reduction process
KM843_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KM843_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KM843_RS00345	COG2002	toxin-antitoxin pair type II binding
KM843_RS00350	COG2244	polysaccharide biosynthetic process
KM843_RS00355	COG3956	TIGRFAM MazG family protein
KM843_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KM843_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KM843_RS00380	COG1098	S1 RNA binding domain
KM843_RS00395	COG2208	phosphoserine phosphatase activity
KM843_RS00400	COG2304	oxidoreductase activity
KM843_RS00405	COG0515	serine threonine protein kinase
KM843_RS00410	COG0037	tRNA processing
KM843_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KM843_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KM843_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM843_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM843_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM843_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
KM843_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM843_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KM843_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KM843_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KM843_RS00475	COG1396	sequence-specific DNA binding
KM843_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM843_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KM843_RS00565	COG4463	regulation of RNA biosynthetic process
KM843_RS00570	COG3880	PFAM UvrB UvrC protein
KM843_RS00580	COG0542	response to heat
KM843_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KM843_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KM843_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
KM843_RS00615	COG1045	serine acetyltransferase
KM843_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KM843_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM843_RS00635	COG3688	RNA-binding protein containing a PIN domain
KM843_RS00640	COG1595	DNA-templated transcription, initiation
KM843_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM843_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
KM843_RS00680	COG2813	Specifically methylates the guanine in position
KM843_RS00695	COG1358	cellular component organization or biogenesis
KM843_RS00720	COG0596	Alpha beta hydrolase
KM843_RS00830	COG0201	protein transport
KM843_RS00840	COG0024	Methionine aminopeptidase
KM843_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KM843_RS00875	COG1122	ATPase activity
KM843_RS00880	COG1122	ATPase activity
KM843_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM843_RS00905	COG2226	methyltransferase
KM843_RS00910	COG2318	DinB family
KM843_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS00925	COG0489	protein tyrosine kinase activity
KM843_RS00935	COG2194	sulfuric ester hydrolase activity
KM843_RS00940	COG0726	polysaccharide deacetylase
KM843_RS01000	COG0738	Major facilitator superfamily
KM843_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM843_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
KM843_RS01025	COG0385	Bile acid
KM843_RS01030	COG2819	hydrolase of the alpha beta superfamily
KM843_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM843_RS01050	COG2207	Transcriptional regulator
KM843_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM843_RS01055	COG3876	Protein conserved in bacteria
KM843_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
KM843_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM843_RS01070	COG1263	PTS System
KM843_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM843_RS01085	COG1683	Conserved Protein
KM843_RS01115	COG1595	DNA-templated transcription, initiation
KM843_RS01120	COG5662	AntiSigma factor
KM843_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM843_RS01130	COG4856	YbbR-like protein
KM843_RS01170	COG2205	protein histidine kinase activity
KM843_RS01180	COG1136	(ABC) transporter
KM843_RS01185	COG0577	efflux transmembrane transporter activity
KM843_RS01190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM843_RS01205	COG1346	cytolysis
KM843_RS01210	COG1380	Effector of murein hydrolase LrgA
KM843_RS01215	COG1846	Transcriptional regulator
KM843_RS01220	COG1113	amino acid transport
KM843_RS01225	COG1011	Hydrolase
KM843_RS01230	COG4585	Histidine kinase
KM843_RS01235	COG2197	response regulator
KM843_RS01240	COG1131	(ABC) transporter
KM843_RS01280	COG0531	amino acid
KM843_RS01295	COG0584	glycerophosphoryl diester phosphodiesterase
KM843_RS01300	COG2271	Major facilitator Superfamily
KM843_RS01310	COG2368	4-hydroxyphenylacetate
KM843_RS01320	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS01335	COG0371	Dehydrogenase
KM843_RS01345	COG1183	phosphatidylcholine synthase activity
KM843_RS01350	COG0586	Pfam SNARE associated Golgi protein
KM843_RS01355	COG0688	phosphatidylethanolamine metabolic process
KM843_RS01370	COG1301	dicarboxylic acid transport
KM843_RS01375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM843_RS01380	COG0833	amino acid
KM843_RS01385	COG2040	homocysteine
KM843_RS01390	COG1115	amino acid carrier protein
KM843_RS01395	COG2066	Belongs to the glutaminase family
KM843_RS01400	COG4191	Histidine kinase
KM843_RS01405	COG0784	Response regulator, receiver
KM843_RS01425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM843_RS01430	COG0778	Nitroreductase
KM843_RS01435	COG0346	lactoylglutathione lyase activity
KM843_RS01440	COG2259	Doxx family
KM843_RS01445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS01455	COG3773	Cell wall hydrolase
KM843_RS01460	COG3540	Alkaline phosphatase
KM843_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KM843_RS01470	COG0805	protein transport
KM843_RS01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM843_RS01485	COG0477	Major facilitator Superfamily
KM843_RS01490	COG1309	transcriptional regulator
KM843_RS01495	COG0252	asparaginase activity
KM843_RS01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KM843_RS01505	COG1405	negative regulation of cell septum assembly
KM843_RS01505	COG3012	SEC-C Motif Domain Protein
KM843_RS01510	COG0667	Aldo Keto reductase
KM843_RS01520	COG1595	DNA-templated transcription, initiation
KM843_RS01525	COG1595	DNA-templated transcription, initiation
KM843_RS01530	COG1876	peptidase activity
KM843_RS01535	COG0457	Tetratricopeptide repeat
KM843_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS01545	COG0366	Alpha amylase catalytic
KM843_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
KM843_RS01555	COG1121	(ABC) transporter
KM843_RS01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KM843_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS01570	COG2310	stress, protein
KM843_RS01575	COG2310	stress, protein
KM843_RS01580	COG2310	stress, protein
KM843_RS01585	COG0861	Integral membrane protein TerC family
KM843_RS01595	COG3853	Toxic anion resistance protein (TelA)
KM843_RS01600	COG0477	Major facilitator Superfamily
KM843_RS01605	COG4175	Glycine betaine
KM843_RS01605	COG0517	IMP dehydrogenase activity
KM843_RS01610	COG4176	ABC-type proline glycine betaine transport system permease component
KM843_RS01615	COG2113	Glycine betaine
KM843_RS01620	COG1473	amidohydrolase
KM843_RS01625	COG1288	antiporter activity
KM843_RS01635	COG0366	Alpha amylase catalytic
KM843_RS01645	COG2814	Major facilitator Superfamily
KM843_RS01650	COG1846	Transcriptional regulator
KM843_RS01655	COG1280	lysine exporter protein (LysE YggA)
KM843_RS01660	COG3403	YqcI/YcgG family
KM843_RS01665	COG1113	amino acid transport
KM843_RS01670	COG3665	Urea carboxylase-associated protein
KM843_RS01685	COG1660	Displays ATPase and GTPase activities
KM843_RS01690	COG1082	Xylose isomerase domain protein TIM barrel
KM843_RS01695	COG2271	Major facilitator Superfamily
KM843_RS01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KM843_RS01705	COG3458	cephalosporin-C deacetylase activity
KM843_RS01710	COG3541	Predicted nucleotidyltransferase
KM843_RS01715	COG0506	proline dehydrogenase activity
KM843_RS01720	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS01725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM843_RS01730	COG2508	Transcriptional regulator
KM843_RS01740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM843_RS01740	COG1587	Uroporphyrinogen-III synthase
KM843_RS01745	COG2146	nitrite reductase [NAD(P)H] activity
KM843_RS01750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM843_RS01755	COG0243	molybdopterin cofactor binding
KM843_RS01760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KM843_RS01765	COG2223	nitrite transmembrane transporter activity
KM843_RS01770	COG0523	cobalamin synthesis protein
KM843_RS01775	COG1063	alcohol dehydrogenase
KM843_RS01780	COG1714	RDD family
KM843_RS01790	COG2723	6-phospho-beta-galactosidase activity
KM843_RS01800	COG3209	COG3209 Rhs family protein
KM843_RS01805	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KM843_RS01810	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KM843_RS01815	COG1733	regulation of RNA biosynthetic process
KM843_RS01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS01835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KM843_RS01850	COG0697	spore germination
KM843_RS01855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM843_RS01865	COG2364	Membrane
KM843_RS01870	COG1126	abc transporter atp-binding protein
KM843_RS01875	COG0765	amino acid transport
KM843_RS01880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM843_RS01885	COG0583	DNA-binding transcription factor activity
KM843_RS01890	COG0163	prenyltransferase activity
KM843_RS01895	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KM843_RS01910	COG3104	oligopeptide transport
KM843_RS01915	COG5434	Belongs to the glycosyl hydrolase 28 family
KM843_RS01925	COG0697	spore germination
KM843_RS01935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KM843_RS01940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS01945	COG0456	acetyltransferase
KM843_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM843_RS01955	COG0765	amino acid transport
KM843_RS01960	COG1126	abc transporter atp-binding protein
KM843_RS01965	COG1473	amidohydrolase
KM843_RS01970	COG2079	MmgE PrpD family protein
KM843_RS01975	COG1136	(ABC) transporter
KM843_RS01980	COG0577	efflux transmembrane transporter activity
KM843_RS01985	COG0745	RESPONSE REGULATOR receiver
KM843_RS01990	COG5002	protein histidine kinase activity
KM843_RS01990	COG3850	Histidine kinase
KM843_RS01995	COG0457	Tetratricopeptide repeat
KM843_RS02010	COG0527	aspartate kinase activity
KM843_RS02015	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS02020	COG4605	iron ion homeostasis
KM843_RS02025	COG4604	ABC transporter, ATP-binding protein
KM843_RS02030	COG4607	ABC-type enterochelin transport system periplasmic component
KM843_RS02035	COG2814	Major facilitator Superfamily
KM843_RS02040	COG1309	transcriptional regulator
KM843_RS02045	COG0778	Nitroreductase
KM843_RS02050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KM843_RS02055	COG0640	Transcriptional regulator
KM843_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM843_RS02065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KM843_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS02075	COG4975	Glucose uptake
KM843_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS02085	COG4549	nuclear export factor GLE1
KM843_RS02090	COG2372	response to copper ion
KM843_RS02090	COG1276	copper resistance
KM843_RS02095	COG1349	DNA-binding transcription factor activity
KM843_RS02105	COG2213	PTS system mannitol-specific
KM843_RS02110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS02120	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KM843_RS02130	COG0561	phosphatase activity
KM843_RS02140	COG1914	H( )-stimulated, divalent metal cation uptake system
KM843_RS02150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KM843_RS02155	COG1984	allophanate hydrolase subunit 2
KM843_RS02160	COG1414	Transcriptional regulator
KM843_RS02165	COG2755	lipolytic protein G-D-S-L family
KM843_RS02175	COG2329	Antibiotic biosynthesis monooxygenase
KM843_RS02180	COG0768	penicillin binding
KM843_RS02185	COG4989	oxidoreductase activity
KM843_RS02190	COG3711	transcriptional antiterminator
KM843_RS02195	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS02200	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS02205	COG1917	Cupin 2, conserved barrel domain protein
KM843_RS02210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM843_RS02215	COG3871	stress protein (general stress protein 26)
KM843_RS02225	COG2814	Major facilitator Superfamily
KM843_RS02230	COG1522	sequence-specific DNA binding
KM843_RS02235	COG0551	DNA topoisomerase type I activity
KM843_RS02235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM843_RS02240	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KM843_RS02245	COG3706	GGDEF domain
KM843_RS02250	COG5298	Protein conserved in bacteria
KM843_RS02255	COG1215	transferase activity, transferring glycosyl groups
KM843_RS02265	COG0531	amino acid
KM843_RS02270	COG0494	nUDIX hydrolase
KM843_RS02275	COG0028	Belongs to the TPP enzyme family
KM843_RS02305	COG0457	Tetratricopeptide repeat
KM843_RS02325	COG1914	H( )-stimulated, divalent metal cation uptake system
KM843_RS02345	COG2076	Multidrug Resistance protein
KM843_RS02350	COG2217	Heavy metal translocating P-type atpase
KM843_RS02355	COG3729	General stress protein
KM843_RS02360	COG0662	Cupin 2, conserved barrel domain protein
KM843_RS02365	COG2329	Antibiotic biosynthesis monooxygenase
KM843_RS02370	COG3546	catalase activity
KM843_RS02375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KM843_RS02380	COG3290	protein histidine kinase activity
KM843_RS02385	COG4565	transcriptional regulatory protein
KM843_RS02390	COG1301	dicarboxylic acid transport
KM843_RS02395	COG0628	permease
KM843_RS02400	COG1131	(ABC) transporter
KM843_RS02405	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM843_RS02415	COG1960	acyl-CoA dehydrogenase activity
KM843_RS02435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS02445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KM843_RS02450	COG0513	Belongs to the DEAD box helicase family
KM843_RS02455	COG3402	PFAM membrane-flanked domain
KM843_RS02460	COG3428	Bacterial PH domain
KM843_RS02465	COG0705	Rhomboid family
KM843_RS02475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KM843_RS02480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM843_RS02485	COG0864	Transcriptional regulator
KM843_RS02490	COG2337	Toxic component of a toxin-antitoxin (TA) module
KM843_RS02495	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS02500	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS02505	COG2172	sigma factor antagonist activity
KM843_RS02510	COG2208	phosphoserine phosphatase activity
KM843_RS02515	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS02525	COG1191	sigma factor activity
KM843_RS02530	COG2208	phosphoserine phosphatase activity
KM843_RS02535	COG2183	response to ionizing radiation
KM843_RS02590	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM843_RS02600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KM843_RS02605	COG1522	sequence-specific DNA binding
KM843_RS02625	COG0477	Major facilitator Superfamily
KM843_RS02640	COG2030	dehydratase
KM843_RS02655	COG1959	2 iron, 2 sulfur cluster binding
KM843_RS02660	COG2910	NAD(P)H-binding
KM843_RS02665	COG1309	transcriptional regulator
KM843_RS02670	COG0300	oxidoreductase activity
KM843_RS02680	COG0604	alcohol dehydrogenase
KM843_RS02690	COG3239	Fatty acid desaturase
KM843_RS02700	COG1278	Cold shock
KM843_RS02705	COG1329	Transcriptional regulator
KM843_RS02710	COG1937	Protein conserved in bacteria
KM843_RS02715	COG2210	Belongs to the sulfur carrier protein TusA family
KM843_RS02725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM843_RS02725	COG0425	Belongs to the sulfur carrier protein TusA family
KM843_RS02735	COG0425	Belongs to the sulfur carrier protein TusA family
KM843_RS02740	COG0730	response to heat
KM843_RS02745	COG1794	racemase activity, acting on amino acids and derivatives
KM843_RS02760	COG0456	acetyltransferase
KM843_RS02760	COG1846	Transcriptional regulator
KM843_RS02765	COG2271	Major facilitator Superfamily
KM843_RS02770	COG3621	Patatin-like phospholipase
KM843_RS02780	COG0662	Cupin 2, conserved barrel domain protein
KM843_RS02795	COG0277	FAD linked oxidase domain protein
KM843_RS02820	COG0662	Cupin 2, conserved barrel domain protein
KM843_RS02830	COG2318	DinB family
KM843_RS02835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KM843_RS02870	COG0351	phosphomethylpyrimidine kinase
KM843_RS02885	COG1064	alcohol dehydrogenase
KM843_RS02890	COG0789	Transcriptional regulator
KM843_RS02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM843_RS02935	COG2814	Major facilitator Superfamily
KM843_RS02940	COG1309	transcriptional regulator
KM843_RS02945	COG0697	spore germination
KM843_RS02950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM843_RS02955	COG5577	PFAM Coat F domain
KM843_RS02965	COG1063	alcohol dehydrogenase
KM843_RS02970	COG5577	PFAM Coat F domain
KM843_RS02980	COG4585	Histidine kinase
KM843_RS02985	COG2197	response regulator
KM843_RS02990	COG2409	Drug exporters of the RND superfamily
KM843_RS02995	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KM843_RS03000	COG0488	(ABC) transporter
KM843_RS03005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM843_RS03010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS03020	COG2814	Major facilitator Superfamily
KM843_RS03025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM843_RS03035	COG0730	response to heat
KM843_RS03040	COG0456	acetyltransferase
KM843_RS03045	COG4978	Transcriptional regulator
KM843_RS03045	COG0789	Transcriptional regulator
KM843_RS03050	COG0697	spore germination
KM843_RS03055	COG1051	belongs to the nudix hydrolase family
KM843_RS03060	COG2226	methyltransferase
KM843_RS03070	COG1802	Transcriptional regulator
KM843_RS03075	COG1819	glycosyl
KM843_RS03090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM843_RS03100	COG1388	LysM domain
KM843_RS03105	COG2814	Major facilitator Superfamily
KM843_RS03110	COG2188	Transcriptional regulator
KM843_RS03115	COG2186	Transcriptional regulator
KM843_RS03120	COG2807	transmembrane transport
KM843_RS03125	COG2076	Multidrug Resistance protein
KM843_RS03130	COG2076	Multidrug Resistance protein
KM843_RS03135	COG1309	transcriptional regulator
KM843_RS03140	COG0531	amino acid
KM843_RS03150	COG3832	glyoxalase III activity
KM843_RS03155	COG0604	alcohol dehydrogenase
KM843_RS03160	COG2814	Major facilitator Superfamily
KM843_RS03200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KM843_RS03205	COG0802	atpase or kinase
KM843_RS03210	COG1214	PFAM Peptidase M22, glycoprotease
KM843_RS03215	COG0456	acetyltransferase
KM843_RS03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KM843_RS03225	COG0488	(ABC) transporter
KM843_RS03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KM843_RS03245	COG0805	protein transport
KM843_RS03255	COG1266	CAAX protease self-immunity
KM843_RS03270	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS03290	COG0457	Tetratricopeptide repeat
KM843_RS03295	COG1063	alcohol dehydrogenase
KM843_RS03300	COG2211	Major facilitator Superfamily
KM843_RS03305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM843_RS03315	COG1842	Phage shock protein A
KM843_RS03320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM843_RS03325	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KM843_RS03330	COG4260	virion core protein, lumpy skin disease virus
KM843_RS03335	COG2755	lipolytic protein G-D-S-L family
KM843_RS03335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KM843_RS03345	COG1595	DNA-templated transcription, initiation
KM843_RS03350	COG1063	alcohol dehydrogenase
KM843_RS03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KM843_RS03360	COG0823	Involved in the tonB-independent uptake of proteins
KM843_RS03375	COG2132	Multicopper oxidase
KM843_RS03380	COG1113	amino acid transport
KM843_RS03385	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM843_RS03390	COG0714	Associated with various cellular activities
KM843_RS03395	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KM843_RS03400	COG1305	Transglutaminase-like
KM843_RS03420	COG2252	PERMEase
KM843_RS03425	COG3064	Membrane
KM843_RS03445	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KM843_RS03450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KM843_RS03455	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KM843_RS03460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KM843_RS03465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KM843_RS03480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KM843_RS03490	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KM843_RS03495	COG0138	bifunctional purine biosynthesis protein purh
KM843_RS03500	COG0151	Belongs to the GarS family
KM843_RS03510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KM843_RS03515	COG1470	cell adhesion involved in biofilm formation
KM843_RS03520	COG4496	protein, YerC YecD
KM843_RS03525	COG0069	glutamate synthase activity
KM843_RS03535	COG0210	DNA helicase
KM843_RS03545	COG4851	CamS sex pheromone cAM373 precursor
KM843_RS03550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM843_RS03555	COG1285	pathogenesis
KM843_RS03560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM843_RS03580	COG1309	transcriptional regulator
KM843_RS03585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KM843_RS03590	COG1597	lipid kinase activity
KM843_RS03595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM843_RS03600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KM843_RS03610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KM843_RS03640	COG5444	nuclease activity
KM843_RS03665	COG3546	catalase activity
KM843_RS03670	COG0454	-acetyltransferase
KM843_RS03680	COG2323	membrane
KM843_RS03685	COG2329	Antibiotic biosynthesis monooxygenase
KM843_RS03690	COG0346	lactoylglutathione lyase activity
KM843_RS03695	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS03700	COG5583	Uncharacterized small protein (DUF2292)
KM843_RS03705	COG0196	riboflavin kinase activity
KM843_RS03710	COG0670	Belongs to the BI1 family
KM843_RS03715	COG1846	Transcriptional regulator
KM843_RS03720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM843_RS03730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KM843_RS03730	COG2124	cytochrome p450
KM843_RS03745	COG1131	(ABC) transporter
KM843_RS03790	COG4106	trans-aconitate 2-methyltransferase activity
KM843_RS03795	COG1368	sulfuric ester hydrolase activity
KM843_RS03800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KM843_RS03805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS03810	COG1442	glycosyl transferase family 8
KM843_RS03815	COG1216	Glycosyl transferase, family 2
KM843_RS03820	COG1442	glycosyl transferase family 8
KM843_RS03825	COG2223	nitrite transmembrane transporter activity
KM843_RS03830	COG0531	amino acid
KM843_RS03835	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS03840	COG0840	transmembrane signaling receptor activity
KM843_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS03850	COG0463	Glycosyl transferase, family 2
KM843_RS03850	COG0457	Tetratricopeptide repeat
KM843_RS03855	COG0488	(ABC) transporter
KM843_RS03860	COG0789	Transcriptional regulator
KM843_RS03865	COG2814	Major facilitator Superfamily
KM843_RS03870	COG0488	(ABC) transporter
KM843_RS03875	COG0513	Belongs to the DEAD box helicase family
KM843_RS03885	COG2130	NADP-dependent
KM843_RS03900	COG3866	Pectate lyase
KM843_RS03905	COG0471	metal ion transport
KM843_RS03930	COG3290	protein histidine kinase activity
KM843_RS03935	COG4565	transcriptional regulatory protein
KM843_RS03940	COG3181	Tripartite tricarboxylate transporter family receptor
KM843_RS03945	COG2851	Citrate transporter
KM843_RS03950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS03955	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KM843_RS03965	COG2258	MOSC domain
KM843_RS03985	COG0024	Methionine aminopeptidase
KM843_RS03990	COG1263	PTS System
KM843_RS03990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS04000	COG1368	sulfuric ester hydrolase activity
KM843_RS04010	COG0071	Belongs to the small heat shock protein (HSP20) family
KM843_RS04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS04025	COG1263	PTS System
KM843_RS04030	COG0366	Alpha amylase catalytic
KM843_RS04035	COG2188	Transcriptional regulator
KM843_RS04040	COG0778	Nitroreductase
KM843_RS04055	COG0737	Belongs to the 5'-nucleotidase family
KM843_RS04060	COG0693	protein deglycase activity
KM843_RS04065	COG1609	Transcriptional regulator
KM843_RS04080	COG2814	Major facilitator Superfamily
KM843_RS04090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM843_RS04095	COG4980	gas vesicle protein
KM843_RS04100	COG1295	ribonuclease BN
KM843_RS04105	COG0477	Major facilitator Superfamily
KM843_RS04110	COG0387	Pfam Sodium calcium exchanger
KM843_RS04120	COG0668	transmembrane transport
KM843_RS04125	COG0535	radical SAM domain protein
KM843_RS04135	COG0726	polysaccharide deacetylase
KM843_RS04140	COG2084	Dehydrogenase
KM843_RS04150	COG0598	Magnesium transport protein CorA
KM843_RS04155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KM843_RS04160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KM843_RS04170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KM843_RS04175	COG4637	Psort location Cytoplasmic, score
KM843_RS04180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM843_RS04185	COG0022	dehydrogenase e1 component
KM843_RS04190	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM843_RS04195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM843_RS04200	COG3284	Transcriptional regulator
KM843_RS04210	COG1486	melibiose metabolic process
KM843_RS04215	COG1737	Transcriptional regulator
KM843_RS04220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS04220	COG1263	PTS System
KM843_RS04225	COG5434	Belongs to the glycosyl hydrolase 28 family
KM843_RS04230	COG1132	(ABC) transporter
KM843_RS04235	COG1132	(ABC) transporter
KM843_RS04240	COG2259	Doxx family
KM843_RS04245	COG2514	catechol 2,3-dioxygenase activity
KM843_RS04255	COG1695	Transcriptional regulator
KM843_RS04260	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM843_RS04265	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KM843_RS04270	COG3848	Pyruvate phosphate dikinase
KM843_RS04270	COG0574	Belongs to the PEP-utilizing enzyme family
KM843_RS04275	COG2732	(Barnase) inhibitor
KM843_RS04280	COG2318	DinB family
KM843_RS04285	COG2814	Major facilitator Superfamily
KM843_RS04290	COG1846	Transcriptional regulator
KM843_RS04295	COG0392	lysyltransferase activity
KM843_RS04295	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KM843_RS04300	COG0384	phenazine biosynthesis protein PhzF
KM843_RS04305	COG0778	Nitroreductase
KM843_RS04320	COG1090	epimerase
KM843_RS04335	COG2814	Major facilitator Superfamily
KM843_RS04345	COG3591	Belongs to the peptidase S1B family
KM843_RS04360	COG3103	Sh3 type 3 domain protein
KM843_RS04365	COG5658	integral membrane protein
KM843_RS04370	COG0596	Alpha beta hydrolase
KM843_RS04375	COG0463	Glycosyl transferase, family 2
KM843_RS04380	COG4485	Bacterial membrane protein, YfhO
KM843_RS04385	COG1988	membrane-bound metal-dependent
KM843_RS04390	COG1194	a g-specific adenine glycosylase
KM843_RS04400	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS04420	COG1132	(ABC) transporter
KM843_RS04425	COG4129	membrane
KM843_RS04435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KM843_RS04440	COG0735	belongs to the Fur family
KM843_RS04550	COG1757	Na H antiporter
KM843_RS04555	COG3340	Belongs to the peptidase S51 family
KM843_RS04565	COG0277	FAD linked oxidase domain protein
KM843_RS04580	COG0753	catalase activity
KM843_RS04590	COG1116	anion transmembrane transporter activity
KM843_RS04595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM843_RS04600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM843_RS04620	COG1476	TRANSCRIPTIONal
KM843_RS04630	COG3382	B3 4 domain protein
KM843_RS04635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KM843_RS04645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KM843_RS04650	COG0789	Transcriptional regulator
KM843_RS04655	COG1664	Polymer-forming cytoskeletal
KM843_RS04660	COG1664	Polymer-forming cytoskeletal
KM843_RS04665	COG2766	serine protein kinase
KM843_RS04675	COG1846	Transcriptional regulator
KM843_RS04680	COG1566	PFAM secretion protein HlyD family protein
KM843_RS04685	COG2814	Major facilitator Superfamily
KM843_RS04690	COG0655	NAD(P)H dehydrogenase (quinone) activity
KM843_RS04705	COG1725	Transcriptional regulator
KM843_RS04710	COG1131	(ABC) transporter
KM843_RS04715	COG1131	(ABC) transporter
KM843_RS04720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM843_RS04725	COG1278	Cold shock
KM843_RS04730	COG1464	Belongs to the NlpA lipoprotein family
KM843_RS04735	COG3706	GGDEF domain
KM843_RS04740	COG1823	symporter activity
KM843_RS04760	COG5577	PFAM Coat F domain
KM843_RS04770	COG3764	Sortase (surface protein transpeptidase)
KM843_RS04775	COG0564	pseudouridine synthase activity
KM843_RS04785	COG0517	IMP dehydrogenase activity
KM843_RS04790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KM843_RS04795	COG3153	acetyltransferase
KM843_RS04795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM843_RS04800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM843_RS04805	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KM843_RS04810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KM843_RS04820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KM843_RS04825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KM843_RS04830	COG2203	Gaf domain
KM843_RS04830	COG4585	Histidine kinase
KM843_RS04835	COG2197	response regulator
KM843_RS04840	COG0431	NADPH-dependent FMN reductase
KM843_RS04855	COG0791	NLP P60 protein
KM843_RS04855	COG1388	LysM domain
KM843_RS04860	COG1959	2 iron, 2 sulfur cluster binding
KM843_RS04870	COG2719	SpoVR family
KM843_RS04875	COG1785	Belongs to the alkaline phosphatase family
KM843_RS04880	COG0791	NLP P60 protein
KM843_RS04880	COG1388	LysM domain
KM843_RS04885	COG0583	DNA-binding transcription factor activity
KM843_RS04890	COG0372	Belongs to the citrate synthase family
KM843_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS04900	COG0531	amino acid
KM843_RS04905	COG0733	neurotransmitter:sodium symporter activity
KM843_RS04920	COG1595	DNA-templated transcription, initiation
KM843_RS04925	COG0204	Acyl-transferase
KM843_RS04930	COG1253	flavin adenine dinucleotide binding
KM843_RS04935	COG0789	Transcriptional regulator
KM843_RS04940	COG0436	Aminotransferase
KM843_RS04945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM843_RS04950	COG1253	flavin adenine dinucleotide binding
KM843_RS04955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM843_RS04960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KM843_RS04965	COG0584	glycerophosphoryl diester phosphodiesterase
KM843_RS04975	COG0668	transmembrane transport
KM843_RS04980	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KM843_RS04985	COG0726	polysaccharide deacetylase
KM843_RS04990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM843_RS04995	COG3226	Transcriptional regulator
KM843_RS05005	COG0589	response to stress
KM843_RS05010	COG1132	(ABC) transporter
KM843_RS05015	COG1132	(ABC) transporter
KM843_RS05020	COG0702	epimerase
KM843_RS05035	COG0189	ligase activity
KM843_RS05040	COG0189	ligase activity
KM843_RS05055	COG4335	DNA alkylation repair
KM843_RS05060	COG0561	phosphatase activity
KM843_RS05065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM843_RS05075	COG0475	glutathione-regulated potassium exporter activity
KM843_RS05080	COG0490	domain, Protein
KM843_RS05090	COG1024	Enoyl-CoA hydratase
KM843_RS05100	COG4152	abc transporter atp-binding protein
KM843_RS05105	COG1668	transmembrane transport
KM843_RS05110	COG0420	3'-5' exonuclease activity
KM843_RS05115	COG4717	serine-type aminopeptidase activity
KM843_RS05130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KM843_RS05165	COG4980	gas vesicle protein
KM843_RS05180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KM843_RS05185	COG0537	adenosine 5'-monophosphoramidase activity
KM843_RS05190	COG1131	(ABC) transporter
KM843_RS05195	COG4473	ABC transporter
KM843_RS05205	COG1473	amidohydrolase
KM843_RS05210	COG3069	C4-dicarboxylate transmembrane transporter activity
KM843_RS05215	COG2329	Antibiotic biosynthesis monooxygenase
KM843_RS05220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM843_RS05230	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KM843_RS05235	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KM843_RS05240	COG1309	transcriptional regulator
KM843_RS05245	COG1511	domain protein
KM843_RS05250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM843_RS05260	COG1363	Peptidase, m42
KM843_RS05265	COG1301	dicarboxylic acid transport
KM843_RS05275	COG1234	tRNA 3'-trailer cleavage
KM843_RS05280	COG0095	Lipoate-protein ligase
KM843_RS05285	COG0702	epimerase
KM843_RS05290	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS05300	COG0501	Belongs to the peptidase M48B family
KM843_RS05305	COG1404	Belongs to the peptidase S8 family
KM843_RS05310	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KM843_RS05315	COG0406	alpha-ribazole phosphatase activity
KM843_RS05320	COG0183	Belongs to the thiolase family
KM843_RS05325	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS05330	COG1268	BioY protein
KM843_RS05335	COG0840	transmembrane signaling receptor activity
KM843_RS05340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM843_RS05340	COG0723	plastoquinol--plastocyanin reductase activity
KM843_RS05345	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS05355	COG4903	ComK protein
KM843_RS05365	COG5646	InterPro IPR014922
KM843_RS05390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM843_RS05405	COG0398	Pfam SNARE associated Golgi protein
KM843_RS05410	COG0681	Belongs to the peptidase S26 family
KM843_RS05415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KM843_RS05420	COG1846	Transcriptional regulator
KM843_RS05425	COG3180	Ammonia monooxygenase
KM843_RS05430	COG2814	Major facilitator Superfamily
KM843_RS05440	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KM843_RS05445	COG2323	membrane
KM843_RS05460	COG0420	3'-5' exonuclease activity
KM843_RS05465	COG0419	ATPase involved in DNA repair
KM843_RS05470	COG1403	HNH endonuclease
KM843_RS05510	COG0179	Fumarylacetoacetate (FAA) hydrolase
KM843_RS05530	COG0367	asparagine synthase
KM843_RS05535	COG1562	ergosterol biosynthetic process
KM843_RS05540	COG0534	Mate efflux family protein
KM843_RS05545	COG2207	Transcriptional regulator
KM843_RS05545	COG1917	Cupin 2, conserved barrel domain protein
KM843_RS05550	COG2318	DinB family
KM843_RS05555	COG1357	PFAM Pentapeptide repeats (8 copies)
KM843_RS05560	COG2153	protein acetylation
KM843_RS05565	COG0646	methionine synthase
KM843_RS05565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KM843_RS05575	COG2996	Protein conserved in bacteria
KM843_RS05580	COG1744	ABC transporter substrate-binding protein PnrA-like
KM843_RS05585	COG0840	transmembrane signaling receptor activity
KM843_RS05590	COG2124	cytochrome p450
KM843_RS05600	COG1307	EDD domain protein, DegV family
KM843_RS05605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS05625	COG0561	phosphatase activity
KM843_RS05630	COG1073	alpha beta
KM843_RS05635	COG2151	metal-sulfur cluster biosynthetic enzyme
KM843_RS05645	COG0277	FAD linked oxidase domain protein
KM843_RS05650	COG2271	Major facilitator Superfamily
KM843_RS05660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KM843_RS05670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM843_RS05675	COG0505	Belongs to the CarA family
KM843_RS05680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KM843_RS05685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KM843_RS05700	COG2267	carboxylic ester hydrolase activity
KM843_RS05710	COG1744	ABC transporter substrate-binding protein PnrA-like
KM843_RS05725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM843_RS05730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KM843_RS05735	COG5504	Zn-dependent protease
KM843_RS05740	COG0444	Belongs to the ABC transporter superfamily
KM843_RS05745	COG4608	Belongs to the ABC transporter superfamily
KM843_RS05755	COG0601	transmembrane transport
KM843_RS05760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM843_RS05770	COG0180	Tryptophanyl-tRNA synthetase
KM843_RS05775	COG4166	transmembrane transport
KM843_RS05780	COG0601	transmembrane transport
KM843_RS05785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM843_RS05790	COG0444	Belongs to the ABC transporter superfamily
KM843_RS05795	COG4608	Belongs to the ABC transporter superfamily
KM843_RS05805	COG0456	acetyltransferase
KM843_RS05810	COG1393	Belongs to the ArsC family
KM843_RS05815	COG0861	Integral membrane protein TerC family
KM843_RS05825	COG4862	establishment of competence for transformation
KM843_RS05830	COG4469	Competence protein
KM843_RS05835	COG1164	Oligoendopeptidase f
KM843_RS05845	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM843_RS05850	COG2346	COG2346, Truncated hemoglobins
KM843_RS05855	COG0741	lytic transglycosylase activity
KM843_RS05860	COG4116	CYTH
KM843_RS05870	COG2357	RelA SpoT domain protein
KM843_RS05875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KM843_RS05880	COG0564	pseudouridine synthase activity
KM843_RS05890	COG0475	glutathione-regulated potassium exporter activity
KM843_RS05890	COG0569	domain protein
KM843_RS05895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KM843_RS05900	COG0352	thiamine-phosphate diphosphorylase activity
KM843_RS05905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM843_RS05910	COG2104	thiamine diphosphate biosynthetic process
KM843_RS05920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM843_RS05925	COG0351	phosphomethylpyrimidine kinase
KM843_RS05930	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KM843_RS05985	COG0210	DNA helicase
KM843_RS06005	COG1131	(ABC) transporter
KM843_RS06015	COG2153	protein acetylation
KM843_RS06025	COG2382	esterase
KM843_RS06030	COG0626	cystathionine gamma-synthase activity
KM843_RS06035	COG0626	cystathionine gamma-synthase activity
KM843_RS06050	COG5444	nuclease activity
KM843_RS06085	COG5444	nuclease activity
KM843_RS06115	COG2367	Beta-lactamase
KM843_RS06120	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KM843_RS06125	COG0477	Major facilitator Superfamily
KM843_RS06130	COG1846	Transcriptional regulator
KM843_RS06140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KM843_RS06145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM843_RS06150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KM843_RS06155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS06155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS06160	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM843_RS06190	COG1285	pathogenesis
KM843_RS06205	COG2205	protein histidine kinase activity
KM843_RS06215	COG3383	formate dehydrogenase (NAD+) activity
KM843_RS06220	COG2427	Protein of unknown function (DUF1641)
KM843_RS06225	COG2124	cytochrome p450
KM843_RS06230	COG1819	glycosyl
KM843_RS06240	COG1587	Uroporphyrinogen-III synthase
KM843_RS06245	COG0390	transport system, permease component
KM843_RS06250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KM843_RS06255	COG0697	spore germination
KM843_RS06260	COG4297	protein containing double-stranded beta helix domain
KM843_RS06270	COG1252	NADH dehydrogenase
KM843_RS06280	COG2211	Major facilitator Superfamily
KM843_RS06285	COG1609	Transcriptional regulator
KM843_RS06290	COG0246	Mannitol dehydrogenase
KM843_RS06295	COG2721	sulfolactate sulfo-lyase activity
KM843_RS06300	COG0730	response to heat
KM843_RS06305	COG2318	DinB family
KM843_RS06310	COG0457	Tetratricopeptide repeat
KM843_RS06320	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS06320	COG1388	LysM domain
KM843_RS06320	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM843_RS06330	COG4195	phage-related replication protein
KM843_RS06335	COG2856	Zn peptidase
KM843_RS06340	COG1396	sequence-specific DNA binding
KM843_RS06355	COG1484	DNA-dependent DNA replication
KM843_RS06375	COG1595	DNA-templated transcription, initiation
KM843_RS06380	COG5484	DNA packaging
KM843_RS06380	COG3728	DNA packaging
KM843_RS06415	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS06415	COG5632	N-Acetylmuramoyl-L-alanine amidase
KM843_RS06430	COG0306	phosphate transporter
KM843_RS06435	COG1392	Phosphate transport regulator
KM843_RS06440	COG0531	amino acid
KM843_RS06445	COG0346	lactoylglutathione lyase activity
KM843_RS06450	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KM843_RS06455	COG0463	Glycosyl transferase, family 2
KM843_RS06465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM843_RS06470	COG0477	Major facilitator Superfamily
KM843_RS06475	COG2362	D-Aminopeptidase
KM843_RS06480	COG0601	transmembrane transport
KM843_RS06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KM843_RS06490	COG0444	Belongs to the ABC transporter superfamily
KM843_RS06495	COG4166	transmembrane transport
KM843_RS06500	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM843_RS06505	COG4948	Mandelate Racemase Muconate Lactonizing
KM843_RS06510	COG0791	NLP P60 protein
KM843_RS06515	COG4608	Belongs to the ABC transporter superfamily
KM843_RS06520	COG2706	6-phosphogluconolactonase activity
KM843_RS06525	COG1834	amidinotransferase
KM843_RS06530	COG1607	acyl-coa hydrolase
KM843_RS06535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM843_RS06540	COG2076	Multidrug Resistance protein
KM843_RS06545	COG2076	Multidrug Resistance protein
KM843_RS06550	COG0788	formyltetrahydrofolate deformylase activity
KM843_RS06555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM843_RS06565	COG1764	response to oxidative stress
KM843_RS06570	COG1846	Transcriptional regulator
KM843_RS06575	COG1764	response to oxidative stress
KM843_RS06590	COG0463	Glycosyl transferase, family 2
KM843_RS06590	COG0457	Tetratricopeptide repeat
KM843_RS06600	COG2814	Major facilitator Superfamily
KM843_RS06605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM843_RS06615	COG1404	Belongs to the peptidase S8 family
KM843_RS06620	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS06625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KM843_RS06630	COG1122	ATPase activity
KM843_RS06635	COG4721	ABC-type cobalt transport system, permease component
KM843_RS06640	COG1388	LysM domain
KM843_RS06640	COG3858	chitin binding
KM843_RS06650	COG2239	Acts as a magnesium transporter
KM843_RS06655	COG0789	Transcriptional regulator
KM843_RS06670	COG1846	Transcriptional regulator
KM843_RS06675	COG0726	polysaccharide deacetylase
KM843_RS06680	COG3285	dna ligase
KM843_RS06680	COG1793	dna ligase
KM843_RS06685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KM843_RS06690	COG0586	Pfam SNARE associated Golgi protein
KM843_RS06700	COG1191	sigma factor activity
KM843_RS06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KM843_RS06730	COG2323	membrane
KM843_RS06740	COG3594	Acyltransferase
KM843_RS06745	COG5002	protein histidine kinase activity
KM843_RS06750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM843_RS06765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KM843_RS06770	COG0436	Aminotransferase
KM843_RS06800	COG3852	Histidine kinase
KM843_RS06805	COG1846	Transcriptional regulator
KM843_RS06810	COG1360	Flagellar Motor Protein
KM843_RS06815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM843_RS06820	COG0542	response to heat
KM843_RS06825	COG3949	Membrane
KM843_RS06840	COG0720	synthase
KM843_RS06845	COG0602	queuosine metabolic process
KM843_RS06860	COG1733	regulation of RNA biosynthetic process
KM843_RS06865	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS06880	COG4873	Protein conserved in bacteria
KM843_RS06890	COG3773	Cell wall hydrolase
KM843_RS06895	COG2244	polysaccharide biosynthetic process
KM843_RS06900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS06905	COG2217	Heavy metal translocating P-type atpase
KM843_RS06910	COG0006	proline dipeptidase activity
KM843_RS06915	COG1609	Transcriptional regulator
KM843_RS06920	COG3711	transcriptional antiterminator
KM843_RS06925	COG2190	(PTS) system
KM843_RS06925	COG1263	PTS System
KM843_RS06925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS06930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS06935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KM843_RS06945	COG1533	DNA photolyase activity
KM843_RS06950	COG0840	transmembrane signaling receptor activity
KM843_RS06955	COG2084	Dehydrogenase
KM843_RS06965	COG2340	Cysteine-rich secretory protein family
KM843_RS06970	COG0768	penicillin binding
KM843_RS06975	COG4191	Histidine kinase
KM843_RS06980	COG0436	Aminotransferase
KM843_RS06990	COG0784	Response regulator, receiver
KM843_RS06990	COG0835	chemotaxis
KM843_RS07000	COG2814	Major facilitator Superfamily
KM843_RS07005	COG1376	ErfK ybiS ycfS ynhG family protein
KM843_RS07010	COG1408	metallophosphoesterase
KM843_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS07025	COG2200	EAL domain
KM843_RS07030	COG4703	Protein of unknown function (DUF1797)
KM843_RS07035	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KM843_RS07045	COG0517	IMP dehydrogenase activity
KM843_RS07050	COG0583	DNA-binding transcription factor activity
KM843_RS07055	COG0716	FMN binding
KM843_RS07065	COG0716	FMN binding
KM843_RS07085	COG0668	transmembrane transport
KM843_RS07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS07110	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM843_RS07115	COG0303	'Molybdopterin
KM843_RS07120	COG1763	Mo-molybdopterin cofactor biosynthetic process
KM843_RS07125	COG0314	molybdopterin synthase activity
KM843_RS07130	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KM843_RS07140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KM843_RS07145	COG1136	(ABC) transporter
KM843_RS07150	COG0577	efflux transmembrane transporter activity
KM843_RS07155	COG1349	DNA-binding transcription factor activity
KM843_RS07160	COG1105	Belongs to the carbohydrate kinase PfkB family
KM843_RS07165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM843_RS07165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM843_RS07165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS07170	COG0681	Belongs to the peptidase S26 family
KM843_RS07180	COG0488	(ABC) transporter
KM843_RS07185	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM843_RS07190	COG2309	aminopeptidase activity
KM843_RS07200	COG1077	Cell shape determining protein MreB Mrl
KM843_RS07205	COG2002	toxin-antitoxin pair type II binding
KM843_RS07210	COG3852	Histidine kinase
KM843_RS07215	COG2105	PFAM AIG2 family protein
KM843_RS07215	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KM843_RS07220	COG0569	domain protein
KM843_RS07230	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM843_RS07240	COG0561	phosphatase activity
KM843_RS07245	COG0242	peptide deformylase activity
KM843_RS07255	COG0497	DNA recombination
KM843_RS07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS07265	COG3321	synthase
KM843_RS07265	COG4221	oxidoreductase activity
KM843_RS07270	COG4221	oxidoreductase activity
KM843_RS07270	COG0300	oxidoreductase activity
KM843_RS07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS07270	COG3321	synthase
KM843_RS07275	COG4221	oxidoreductase activity
KM843_RS07275	COG3321	synthase
KM843_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS07275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS07280	COG0300	oxidoreductase activity
KM843_RS07280	COG3321	synthase
KM843_RS07280	COG4221	oxidoreductase activity
KM843_RS07285	COG4221	oxidoreductase activity
KM843_RS07285	COG3321	synthase
KM843_RS07285	COG0300	oxidoreductase activity
KM843_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS07290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS07290	COG0300	oxidoreductase activity
KM843_RS07290	COG3321	synthase
KM843_RS07290	COG4221	oxidoreductase activity
KM843_RS07295	COG4221	oxidoreductase activity
KM843_RS07295	COG3321	synthase
KM843_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS07300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM843_RS07305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM843_RS07310	COG0022	dehydrogenase e1 component
KM843_RS07315	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM843_RS07320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM843_RS07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS07340	COG1982	Orn Lys Arg decarboxylase major
KM843_RS07360	COG0483	inositol monophosphate 1-phosphatase activity
KM843_RS07370	COG3227	Zinc metalloprotease (Elastase)
KM843_RS07385	COG1595	DNA-templated transcription, initiation
KM843_RS07405	COG1217	gtp-binding protein TYPA
KM843_RS07415	COG4896	Protein conserved in bacteria
KM843_RS07425	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KM843_RS07430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM843_RS07435	COG2066	Belongs to the glutaminase family
KM843_RS07445	COG0772	Belongs to the SEDS family
KM843_RS07450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KM843_RS07465	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM843_RS07465	COG2010	Cytochrome c
KM843_RS07470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM843_RS07475	COG1845	cytochrome c oxidase, subunit III
KM843_RS07480	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KM843_RS07485	COG3336	cytochrome c oxidase
KM843_RS07495	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KM843_RS07500	COG2340	Cysteine-rich secretory protein family
KM843_RS07515	COG3679	Belongs to the UPF0342 family
KM843_RS07525	COG0742	ribosomal rna small subunit methyltransferase
KM843_RS07535	COG3314	Sporulation integral membrane protein YlbJ
KM843_RS07540	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM843_RS07545	COG3480	Lon protease (S16) C-terminal proteolytic domain
KM843_RS07555	COG1399	metal-binding, possibly nucleic acid-binding protein
KM843_RS07575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KM843_RS07595	COG4839	cell division protein FtsL
KM843_RS07600	COG0768	penicillin binding
KM843_RS07605	COG0768	penicillin binding
KM843_RS07625	COG0772	Belongs to the SEDS family
KM843_RS07640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KM843_RS07645	COG0849	cell division
KM843_RS07650	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KM843_RS07655	COG1404	Belongs to the peptidase S8 family
KM843_RS07655	COG4412	M6 family metalloprotease domain protein
KM843_RS07665	COG1191	sigma factor activity
KM843_RS07670	COG1191	sigma factor activity
KM843_RS07675	COG1119	ATPase activity
KM843_RS07680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM843_RS07685	COG1873	PFAM PRC-barrel domain
KM843_RS07690	COG1496	oxidoreductase activity
KM843_RS07695	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KM843_RS07705	COG0762	integral membrane protein
KM843_RS07710	COG2302	S4 RNA-binding domain
KM843_RS07715	COG3599	regulation of cell shape
KM843_RS07720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KM843_RS07725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM843_RS07735	COG0564	pseudouridine synthase activity
KM843_RS07745	COG2233	PERMEase
KM843_RS07755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KM843_RS07760	COG0505	Belongs to the CarA family
KM843_RS07765	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KM843_RS07780	COG0284	orotidine-5'-phosphate decarboxylase activity
KM843_RS07785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KM843_RS07795	COG0306	phosphate transporter
KM843_RS07810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KM843_RS07815	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KM843_RS07820	COG1648	precorrin-2 dehydrogenase activity
KM843_RS07830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KM843_RS07835	COG1561	YicC-like family, N-terminal region
KM843_RS07845	COG0194	GDP metabolic process
KM843_RS07855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM843_RS07860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KM843_RS07865	COG0242	peptide deformylase activity
KM843_RS07875	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KM843_RS07875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KM843_RS07885	COG0631	protein serine/threonine phosphatase activity
KM843_RS07890	COG0515	serine threonine protein kinase
KM843_RS07890	COG2815	serine threonine protein kinase
KM843_RS07900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KM843_RS07905	COG1564	THIamine pyrophosphokinase
KM843_RS07920	COG1302	Protein conserved in bacteria
KM843_RS07925	COG1461	Dihydroxyacetone kinase
KM843_RS07930	COG1760	l-serine dehydratase
KM843_RS07935	COG1760	l-serine dehydratase
KM843_RS07940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KM843_RS07955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM843_RS07960	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS07975	COG1196	nuclear chromosome segregation
KM843_RS07980	COG0552	protein localization to endoplasmic reticulum
KM843_RS07995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KM843_RS08005	COG1837	Belongs to the UPF0109 family
KM843_RS08030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM843_RS08045	COG2257	FlhB HrpN YscU SpaS Family
KM843_RS08055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KM843_RS08060	COG0758	DNA mediated transformation
KM843_RS08065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KM843_RS08075	COG4974	Belongs to the 'phage' integrase family
KM843_RS08095	COG1815	bacterial-type flagellum-dependent cell motility
KM843_RS08100	COG1558	bacterial-type flagellum-dependent cell motility
KM843_RS08105	COG1677	Flagellar hook-basal body complex protein FliE
KM843_RS08110	COG1766	The M ring may be actively involved in energy transduction
KM843_RS08115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM843_RS08120	COG1317	bacterial-type flagellum organization
KM843_RS08125	COG1157	protein secretion by the type III secretion system
KM843_RS08130	COG2882	bacterial-type flagellum organization
KM843_RS08135	COG3334	PFAM MgtE intracellular
KM843_RS08140	COG3144	bacterial-type flagellum assembly
KM843_RS08145	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KM843_RS08150	COG4786	Flagellar basal body rod
KM843_RS08155	COG1582	Flagellar protein (FlbD)
KM843_RS08160	COG1580	Controls the rotational direction of flagella during chemotaxis
KM843_RS08165	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM843_RS08170	COG1776	CheC inhibitor of MCP methylation
KM843_RS08170	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KM843_RS08175	COG2201	protein-glutamate methylesterase activity
KM843_RS08180	COG3190	flagellar
KM843_RS08185	COG1338	Plays a role in the flagellum-specific transport system
KM843_RS08190	COG1987	bacterial-type flagellum assembly
KM843_RS08195	COG1684	flagellar biosynthetic protein fliR
KM843_RS08200	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM843_RS08205	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KM843_RS08210	COG1419	protein localization to endoplasmic reticulum
KM843_RS08215	COG0455	bacterial-type flagellum organization
KM843_RS08220	COG2201	protein-glutamate methylesterase activity
KM843_RS08225	COG2198	Histidine kinase
KM843_RS08225	COG0643	Histidine kinase
KM843_RS08230	COG0835	chemotaxis
KM843_RS08235	COG1776	CheC inhibitor of MCP methylation
KM843_RS08245	COG1191	sigma factor activity
KM843_RS08275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KM843_RS08280	COG4589	Belongs to the CDS family
KM843_RS08290	COG0750	zinc metalloprotease
KM843_RS08310	COG0195	Participates in both transcription termination and antitermination
KM843_RS08315	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KM843_RS08320	COG1358	cellular component organization or biogenesis
KM843_RS08330	COG1550	Protein conserved in bacteria
KM843_RS08345	COG0196	riboflavin kinase activity
KM843_RS08360	COG0726	polysaccharide deacetylase
KM843_RS08365	COG0612	Peptidase, M16
KM843_RS08370	COG1873	PFAM PRC-barrel domain
KM843_RS08375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM843_RS08380	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KM843_RS08385	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KM843_RS08390	COG0527	aspartate kinase activity
KM843_RS08400	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KM843_RS08405	COG0740	serine-type endopeptidase activity
KM843_RS08415	COG1674	ftsk spoiiie
KM843_RS08415	COG4980	gas vesicle protein
KM843_RS08420	COG2188	Transcriptional regulator
KM843_RS08425	COG2814	Major facilitator Superfamily
KM843_RS08430	COG1846	Transcriptional regulator
KM843_RS08435	COG2409	Drug exporters of the RND superfamily
KM843_RS08435	COG1033	growth of symbiont in host cell
KM843_RS08440	COG0612	Peptidase, M16
KM843_RS08445	COG0612	Peptidase, M16
KM843_RS08450	COG0300	oxidoreductase activity
KM843_RS08465	COG1426	Protein conserved in bacteria
KM843_RS08470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KM843_RS08485	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KM843_RS08495	COG1692	metallophosphoesterase
KM843_RS08500	COG2359	stage V sporulation protein S
KM843_RS08520	COG4550	Control of competence regulator ComK, YlbF/YmcA
KM843_RS08565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS08570	COG3425	synthase
KM843_RS08575	COG1024	Enoyl-CoA hydratase
KM843_RS08580	COG1024	Enoyl-CoA hydratase
KM843_RS08585	COG0300	oxidoreductase activity
KM843_RS08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS08585	COG3321	synthase
KM843_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS08585	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS08590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS08590	COG3321	synthase
KM843_RS08590	COG0300	oxidoreductase activity
KM843_RS08590	COG4221	oxidoreductase activity
KM843_RS08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS08595	COG3321	synthase
KM843_RS08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS08595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS08595	COG3321	synthase
KM843_RS08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS08600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS08600	COG3321	synthase
KM843_RS08600	COG4221	oxidoreductase activity
KM843_RS08605	COG3321	synthase
KM843_RS08605	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KM843_RS08605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS08605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KM843_RS08610	COG2124	cytochrome p450
KM843_RS08615	COG3209	COG3209 Rhs family protein
KM843_RS08620	COG3619	membrane
KM843_RS08630	COG1404	Belongs to the peptidase S8 family
KM843_RS08640	COG4195	phage-related replication protein
KM843_RS08645	COG1764	response to oxidative stress
KM843_RS08655	COG2076	Multidrug Resistance protein
KM843_RS08695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM843_RS08700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM843_RS08705	COG4112	unkown
KM843_RS08710	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS08715	COG0464	growth
KM843_RS08720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KM843_RS08725	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KM843_RS08730	COG0789	Transcriptional regulator
KM843_RS08735	COG0174	glutamine synthetase
KM843_RS08760	COG2211	Major facilitator Superfamily
KM843_RS08765	COG3507	Belongs to the glycosyl hydrolase 43 family
KM843_RS08780	COG1070	Carbohydrate kinase
KM843_RS08785	COG0574	Belongs to the PEP-utilizing enzyme family
KM843_RS08785	COG3848	Pyruvate phosphate dikinase
KM843_RS08810	COG2318	DinB family
KM843_RS08815	COG1064	alcohol dehydrogenase
KM843_RS08830	COG0456	acetyltransferase
KM843_RS08865	COG3397	chitin binding
KM843_RS08885	COG5434	Belongs to the glycosyl hydrolase 28 family
KM843_RS08890	COG0756	dUTP diphosphatase activity
KM843_RS08900	COG4195	phage-related replication protein
KM843_RS08935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KM843_RS08945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KM843_RS08965	COG0785	Cytochrome C biogenesis protein
KM843_RS08970	COG2201	protein-glutamate methylesterase activity
KM843_RS08975	COG4846	Membrane protein involved in cytochrome C biogenesis
KM843_RS08985	COG0071	Belongs to the small heat shock protein (HSP20) family
KM843_RS09000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KM843_RS09005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS09025	COG0824	Thioesterase
KM843_RS09035	COG4841	protein insertion into membrane
KM843_RS09045	COG1832	CoA-binding protein
KM843_RS09050	COG0187	DNA topoisomerase II activity
KM843_RS09055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM843_RS09065	COG1115	amino acid carrier protein
KM843_RS09075	COG1063	alcohol dehydrogenase
KM843_RS09080	COG0800	Aldolase
KM843_RS09085	COG1312	Catalyzes the dehydration of D-mannonate
KM843_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS09095	COG1609	Transcriptional regulator
KM843_RS09100	COG2271	Major facilitator Superfamily
KM843_RS09145	COG2205	protein histidine kinase activity
KM843_RS09150	COG0745	RESPONSE REGULATOR receiver
KM843_RS09160	COG3507	Belongs to the glycosyl hydrolase 43 family
KM843_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS09190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM843_RS09195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM843_RS09200	COG2610	gluconate transmembrane transporter activity
KM843_RS09205	COG2124	cytochrome p450
KM843_RS09225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM843_RS09235	COG2246	polysaccharide biosynthetic process
KM843_RS09240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM843_RS09245	COG0586	Pfam SNARE associated Golgi protein
KM843_RS09250	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM843_RS09255	COG1024	Enoyl-CoA hydratase
KM843_RS09260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KM843_RS09265	COG0511	ligase activity, forming carbon-carbon bonds
KM843_RS09270	COG0439	Biotin carboxylase
KM843_RS09275	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS09280	COG1960	acyl-CoA dehydrogenase activity
KM843_RS09285	COG1649	PFAM Uncharacterised BCR, COG1649
KM843_RS09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS09295	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KM843_RS09300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS09305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS09310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS09315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS09320	COG2027	D-alanyl-D-alanine carboxypeptidase
KM843_RS09325	COG2017	converts alpha-aldose to the beta-anomer
KM843_RS09330	COG0534	Mate efflux family protein
KM843_RS09345	COG0582	viral genome integration into host DNA
KM843_RS09350	COG0166	Belongs to the GPI family
KM843_RS09355	COG0405	Gamma-glutamyltransferase
KM843_RS09360	COG2814	Major facilitator Superfamily
KM843_RS09365	COG0640	Transcriptional regulator
KM843_RS09370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KM843_RS09380	COG0604	alcohol dehydrogenase
KM843_RS09390	COG0493	'glutamate synthase
KM843_RS09395	COG0067	glutamate synthase
KM843_RS09395	COG0069	glutamate synthase activity
KM843_RS09395	COG0070	glutamate synthase
KM843_RS09400	COG0583	DNA-binding transcription factor activity
KM843_RS09405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KM843_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS09440	COG0300	oxidoreductase activity
KM843_RS09445	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KM843_RS09455	COG2814	Major facilitator Superfamily
KM843_RS09460	COG1070	Carbohydrate kinase
KM843_RS09465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM843_RS09470	COG0243	molybdopterin cofactor binding
KM843_RS09500	COG5444	nuclease activity
KM843_RS09505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM843_RS09510	COG2207	Transcriptional regulator
KM843_RS09510	COG0662	Cupin 2, conserved barrel domain protein
KM843_RS09515	COG1309	transcriptional regulator
KM843_RS09520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS09530	COG0640	Transcriptional regulator
KM843_RS09535	COG0741	lytic transglycosylase activity
KM843_RS09540	COG2322	membrane
KM843_RS09555	COG1619	proteins homologs of microcin C7 resistance protein MccF
KM843_RS09565	COG1388	LysM domain
KM843_RS09565	COG3584	3D domain protein
KM843_RS09570	COG0514	ATP-dependent DNA helicase (RecQ)
KM843_RS09580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KM843_RS09585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM843_RS09600	COG0071	Belongs to the small heat shock protein (HSP20) family
KM843_RS09630	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS09635	COG1657	PFAM Prenyltransferase squalene oxidase
KM843_RS09640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM843_RS09645	COG0733	neurotransmitter:sodium symporter activity
KM843_RS09650	COG0385	Bile acid
KM843_RS09655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS09660	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM843_RS09670	COG4548	von Willebrand factor, type A
KM843_RS09675	COG0714	Associated with various cellular activities
KM843_RS09680	COG2032	superoxide dismutase activity
KM843_RS09685	COG0791	NLP P60 protein
KM843_RS09685	COG1388	LysM domain
KM843_RS09690	COG1819	glycosyl
KM843_RS09695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KM843_RS09700	COG0534	Mate efflux family protein
KM843_RS09705	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS09710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM843_RS09715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM843_RS09725	COG2962	Rard protein
KM843_RS09740	COG1942	4-Oxalocrotonate Tautomerase
KM843_RS09750	COG1733	regulation of RNA biosynthetic process
KM843_RS09755	COG0778	Nitroreductase
KM843_RS09760	COG0400	carboxylic ester hydrolase activity
KM843_RS09765	COG0346	lactoylglutathione lyase activity
KM843_RS09775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KM843_RS09785	COG2723	6-phospho-beta-galactosidase activity
KM843_RS09790	COG2188	Transcriptional regulator
KM843_RS09795	COG0793	Belongs to the peptidase S41A family
KM843_RS09795	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS09800	COG2226	methyltransferase
KM843_RS09810	COG1876	peptidase activity
KM843_RS09830	COG0671	phosphoesterase, PA-phosphatase related
KM843_RS09865	COG1509	lysine 2,3-aminomutase activity
KM843_RS09870	COG0456	acetyltransferase
KM843_RS09875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM843_RS09880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KM843_RS09885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KM843_RS09890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KM843_RS09905	COG0456	acetyltransferase
KM843_RS09910	COG0463	Glycosyl transferase, family 2
KM843_RS09925	COG4641	Protein conserved in bacteria
KM843_RS09935	COG1086	Polysaccharide biosynthesis protein
KM843_RS09955	COG1388	LysM domain
KM843_RS09960	COG0457	Tetratricopeptide repeat
KM843_RS09975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS09975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM843_RS09990	COG4585	Histidine kinase
KM843_RS09995	COG0730	response to heat
KM843_RS10040	COG1846	Transcriptional regulator
KM843_RS10045	COG4698	Protein conserved in bacteria
KM843_RS10050	COG2755	lipolytic protein G-D-S-L family
KM843_RS10055	COG1999	signal sequence binding
KM843_RS10065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KM843_RS10070	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KM843_RS10075	COG1272	protein, Hemolysin III
KM843_RS10080	COG0204	Acyl-transferase
KM843_RS10085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM843_RS10100	COG2136	Putative SAM-dependent methyltransferase
KM843_RS10100	COG2521	methyltransferase
KM843_RS10115	COG1413	lyase activity
KM843_RS10120	COG1418	mRNA catabolic process
KM843_RS10125	COG0386	Belongs to the glutathione peroxidase family
KM843_RS10135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KM843_RS10145	COG1278	Cold shock
KM843_RS10165	COG0328	RNA-DNA hybrid ribonuclease activity
KM843_RS10170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KM843_RS10175	COG0328	RNA-DNA hybrid ribonuclease activity
KM843_RS10185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM843_RS10200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM843_RS10210	COG1755	Isoprenylcysteine carboxyl methyltransferase
KM843_RS10215	COG3424	synthase
KM843_RS10235	COG2323	membrane
KM843_RS10240	COG1335	isochorismatase
KM843_RS10250	COG2233	PERMEase
KM843_RS10260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KM843_RS10265	COG1199	ATP-dependent helicase activity
KM843_RS10285	COG0116	Belongs to the methyltransferase superfamily
KM843_RS10315	COG3359	exonuclease
KM843_RS10320	COG1111	helicase
KM843_RS10320	COG1205	dead DEAH box helicase
KM843_RS10325	COG2190	(PTS) system
KM843_RS10330	COG0071	Belongs to the small heat shock protein (HSP20) family
KM843_RS10370	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM843_RS10370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM843_RS10380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KM843_RS10385	COG3935	DnaD domain protein
KM843_RS10395	COG0436	Aminotransferase
KM843_RS10400	COG5353	protein conserved in bacteria
KM843_RS10410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KM843_RS10410	COG1199	ATP-dependent helicase activity
KM843_RS10440	COG0438	transferase activity, transferring glycosyl groups
KM843_RS10445	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM843_RS10460	COG1694	Mazg nucleotide pyrophosphohydrolase
KM843_RS10465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS10470	COG2140	Oxalate decarboxylase
KM843_RS10480	COG4347	Protein of unknown function (DUF1405)
KM843_RS10485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM843_RS10485	COG2010	Cytochrome c
KM843_RS10490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KM843_RS10495	COG0723	plastoquinol--plastocyanin reductase activity
KM843_RS10510	COG0457	Tetratricopeptide repeat
KM843_RS10520	COG0287	Prephenate dehydrogenase
KM843_RS10555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KM843_RS10560	COG4401	Chorismate mutase type I
KM843_RS10575	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KM843_RS10580	COG0105	UTP biosynthetic process
KM843_RS10585	COG0142	geranyltranstransferase activity
KM843_RS10595	COG0142	geranyltranstransferase activity
KM843_RS10610	COG0776	regulation of translation
KM843_RS10615	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KM843_RS10655	COG0539	negative regulation of cytoplasmic translation
KM843_RS10675	COG2959	enzyme of heme biosynthesis
KM843_RS10680	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS10680	COG3773	Cell wall hydrolase
KM843_RS10685	COG2339	peptidase activity
KM843_RS10690	COG0492	ferredoxin-NADP+ reductase activity
KM843_RS10695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM843_RS10700	COG4862	establishment of competence for transformation
KM843_RS10705	COG1408	metallophosphoesterase
KM843_RS10715	COG1388	LysM domain
KM843_RS10720	COG1266	CAAX protease self-immunity
KM843_RS10725	COG0514	ATP-dependent DNA helicase (RecQ)
KM843_RS10730	COG4955	Helix-turn-helix domain
KM843_RS10735	COG1141	Ferredoxin
KM843_RS10740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KM843_RS10745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KM843_RS10755	COG1595	DNA-templated transcription, initiation
KM843_RS10760	COG5002	protein histidine kinase activity
KM843_RS10765	COG0745	RESPONSE REGULATOR receiver
KM843_RS10770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM843_RS10775	COG1333	cytochrome c biogenesis protein
KM843_RS10780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS10785	COG1187	pseudouridine synthase activity
KM843_RS10790	COG0700	Nucleoside recognition
KM843_RS10795	COG2715	membrane protein required for spore maturation
KM843_RS10800	COG1686	Belongs to the peptidase S11 family
KM843_RS10825	COG1547	Domain of unknown function (DUF309)
KM843_RS10830	COG0456	acetyltransferase
KM843_RS10845	COG0307	riboflavin synthase, alpha
KM843_RS10850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM843_RS10850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KM843_RS10860	COG0681	Belongs to the peptidase S26 family
KM843_RS10870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KM843_RS10875	COG4086	secreted protein
KM843_RS10880	COG0019	diaminopimelate decarboxylase activity
KM843_RS10885	COG0697	spore germination
KM843_RS10900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KM843_RS10920	COG1191	sigma factor activity
KM843_RS10930	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS10935	COG1686	Belongs to the peptidase S11 family
KM843_RS10940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KM843_RS10945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KM843_RS10950	COG4974	Belongs to the 'phage' integrase family
KM843_RS10960	COG0735	belongs to the Fur family
KM843_RS10965	COG1300	Membrane
KM843_RS10980	COG0281	malic enzyme
KM843_RS10985	COG1757	Na H antiporter
KM843_RS10990	COG1027	Aspartate ammonia-lyase
KM843_RS10995	COG0252	asparaginase activity
KM843_RS11000	COG1396	sequence-specific DNA binding
KM843_RS11005	COG1379	DNA repair
KM843_RS11010	COG0494	nUDIX hydrolase
KM843_RS11020	COG0667	Aldo Keto reductase
KM843_RS11030	COG1073	alpha beta
KM843_RS11040	COG4918	Iron-sulphur cluster biosynthesis
KM843_RS11045	COG0456	acetyltransferase
KM843_RS11045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KM843_RS11050	COG2329	Antibiotic biosynthesis monooxygenase
KM843_RS11055	COG0456	acetyltransferase
KM843_RS11060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KM843_RS11075	COG0628	permease
KM843_RS11085	COG0346	lactoylglutathione lyase activity
KM843_RS11095	COG3048	D-serine ammonia-lyase activity
KM843_RS11100	COG0300	oxidoreductase activity
KM843_RS11105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS11110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM843_RS11115	COG1024	Enoyl-CoA hydratase
KM843_RS11120	COG3425	synthase
KM843_RS11125	COG2124	cytochrome p450
KM843_RS11130	COG3321	synthase
KM843_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS11135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS11135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS11135	COG3321	synthase
KM843_RS11140	COG3321	synthase
KM843_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11140	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS11140	COG0300	oxidoreductase activity
KM843_RS11145	COG3321	synthase
KM843_RS11145	COG0300	oxidoreductase activity
KM843_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS11145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11150	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS11150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS11150	COG3321	synthase
KM843_RS11155	COG0300	oxidoreductase activity
KM843_RS11155	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11155	COG3321	synthase
KM843_RS11160	COG3321	synthase
KM843_RS11160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KM843_RS11160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS11160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS11170	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS11185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KM843_RS11185	COG2070	2-Nitropropane dioxygenase
KM843_RS11190	COG0250	Participates in transcription elongation, termination and antitermination
KM843_RS11210	COG0596	Alpha beta hydrolase
KM843_RS11225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KM843_RS11230	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KM843_RS11245	COG0706	membrane insertase activity
KM843_RS11250	COG2195	Cleaves the N-terminal amino acid of tripeptides
KM843_RS11255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KM843_RS11260	COG0346	lactoylglutathione lyase activity
KM843_RS11270	COG1376	ErfK ybiS ycfS ynhG family protein
KM843_RS11275	COG4129	membrane
KM843_RS11280	COG1126	abc transporter atp-binding protein
KM843_RS11285	COG0765	amino acid transport
KM843_RS11290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM843_RS11300	COG1597	lipid kinase activity
KM843_RS11305	COG0508	dehydrogenase complex catalyzes the overall conversion of
KM843_RS11310	COG0022	dehydrogenase e1 component
KM843_RS11315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KM843_RS11320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KM843_RS11325	COG3426	butyrate kinase activity
KM843_RS11330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM843_RS11335	COG0280	phosphate acetyltransferase
KM843_RS11340	COG3290	protein histidine kinase activity
KM843_RS11340	COG3829	transcription factor binding
KM843_RS11350	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KM843_RS11355	COG2079	MmgE PrpD family protein
KM843_RS11360	COG0372	Belongs to the citrate synthase family
KM843_RS11365	COG1960	acyl-CoA dehydrogenase activity
KM843_RS11370	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM843_RS11375	COG0183	Belongs to the thiolase family
KM843_RS11380	COG0584	glycerophosphoryl diester phosphodiesterase
KM843_RS11385	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS11410	COG1902	pentaerythritol trinitrate reductase activity
KM843_RS11425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KM843_RS11430	COG0745	RESPONSE REGULATOR receiver
KM843_RS11435	COG0750	zinc metalloprotease
KM843_RS11440	COG0497	DNA recombination
KM843_RS11450	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KM843_RS11460	COG0142	geranyltranstransferase activity
KM843_RS11470	COG1570	exodeoxyribonuclease VII activity
KM843_RS11485	COG1302	Protein conserved in bacteria
KM843_RS11490	COG0439	Biotin carboxylase
KM843_RS11495	COG0511	ligase activity, forming carbon-carbon bonds
KM843_RS11535	COG3854	ATPases associated with a variety of cellular activities
KM843_RS11550	COG0006	proline dipeptidase activity
KM843_RS11560	COG3872	metal-dependent enzyme
KM843_RS11570	COG1752	Esterase of the alpha-beta hydrolase superfamily
KM843_RS11585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM843_RS11605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM843_RS11620	COG1396	sequence-specific DNA binding
KM843_RS11630	COG0681	Belongs to the peptidase S26 family
KM843_RS11655	COG4940	Competence protein ComGF
KM843_RS11665	COG4970	Tfp pilus assembly protein FimT
KM843_RS11670	COG4537	Required for transformation and DNA binding
KM843_RS11675	COG1459	type II secretion system
KM843_RS11680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM843_RS11685	COG0598	Magnesium transport protein CorA
KM843_RS11690	COG1253	flavin adenine dinucleotide binding
KM843_RS11695	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS11705	COG1393	Belongs to the ArsC family
KM843_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS11725	COG0011	TIGRFAM Protein of
KM843_RS11735	COG2866	Carboxypeptidase
KM843_RS11740	COG1940	carbohydrate kinase activity
KM843_RS11745	COG4483	Protein conserved in bacteria
KM843_RS11750	COG1757	Na H antiporter
KM843_RS11760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KM843_RS11775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM843_RS11780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KM843_RS11785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KM843_RS11790	COG0581	inorganic phosphate transmembrane transporter activity
KM843_RS11795	COG0573	inorganic phosphate transmembrane transporter activity
KM843_RS11800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KM843_RS11810	COG0768	penicillin binding
KM843_RS11815	COG0477	Major facilitator Superfamily
KM843_RS11820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KM843_RS11825	COG2839	Protein conserved in bacteria
KM843_RS11830	COG5521	maltodextrose utilization protein MalA
KM843_RS11835	COG1388	LysM domain
KM843_RS11845	COG4709	membrane
KM843_RS11850	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KM843_RS11855	COG0735	belongs to the Fur family
KM843_RS11860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS11875	COG0513	Belongs to the DEAD box helicase family
KM843_RS11890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KM843_RS11895	COG2384	SAM-dependent methyltransferase
KM843_RS11900	COG2010	Cytochrome c
KM843_RS11905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KM843_RS11910	COG0358	DNA primase activity
KM843_RS11925	COG0517	IMP dehydrogenase activity
KM843_RS11930	COG0751	glycine-tRNA ligase activity
KM843_RS11950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KM843_RS11955	COG0295	cytidine deaminase activity
KM843_RS11960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KM843_RS11970	COG1480	7TM receptor with intracellular HD hydrolase
KM843_RS11975	COG1702	phosphate starvation-inducible protein PhoH
KM843_RS11980	COG0561	phosphatase activity
KM843_RS11995	COG4864	UPF0365 protein
KM843_RS12000	COG1030	water channel activity
KM843_RS12005	COG1610	YqeY-like protein
KM843_RS12015	COG1283	sodium-dependent phosphate transmembrane transporter activity
KM843_RS12020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KM843_RS12025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KM843_RS12055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KM843_RS12070	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS12100	COG2333	competence protein COMEC
KM843_RS12100	COG0658	competence protein
KM843_RS12105	COG2131	deaminase
KM843_RS12110	COG1555	photosystem II stabilization
KM843_RS12110	COG1596	polysaccharide export
KM843_RS12115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KM843_RS12120	COG2226	methyltransferase
KM843_RS12125	COG0799	negative regulation of ribosome biogenesis
KM843_RS12130	COG1713	HD superfamily hydrolase involved in NAD metabolism
KM843_RS12140	COG1534	Rna-binding protein
KM843_RS12145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KM843_RS12150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KM843_RS12155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KM843_RS12165	COG2755	lipolytic protein G-D-S-L family
KM843_RS12175	COG0398	Pfam SNARE associated Golgi protein
KM843_RS12210	COG0642	Histidine kinase
KM843_RS12210	COG5002	protein histidine kinase activity
KM843_RS12215	COG0745	RESPONSE REGULATOR receiver
KM843_RS12220	COG2311	Membrane
KM843_RS12225	COG0454	-acetyltransferase
KM843_RS12230	COG0563	adenylate kinase activity
KM843_RS12245	COG2318	DinB family
KM843_RS12255	COG0561	phosphatase activity
KM843_RS12260	COG0561	phosphatase activity
KM843_RS12270	COG1482	cell wall glycoprotein biosynthetic process
KM843_RS12275	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM843_RS12275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KM843_RS12275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS12280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS12280	COG3711	transcriptional antiterminator
KM843_RS12290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KM843_RS12295	COG0583	DNA-binding transcription factor activity
KM843_RS12300	COG2814	Major facilitator Superfamily
KM843_RS12305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KM843_RS12305	COG2124	cytochrome p450
KM843_RS12310	COG1309	transcriptional regulator
KM843_RS12315	COG2226	methyltransferase
KM843_RS12330	COG2116	formate transmembrane transporter activity
KM843_RS12335	COG5609	conserved protein (DUF2294)
KM843_RS12340	COG3383	formate dehydrogenase (NAD+) activity
KM843_RS12345	COG2427	Protein of unknown function (DUF1641)
KM843_RS12355	COG0626	cystathionine gamma-synthase activity
KM843_RS12360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM843_RS12385	COG0768	penicillin binding
KM843_RS12400	COG0826	peptidase U32
KM843_RS12405	COG0826	peptidase U32
KM843_RS12410	COG4122	O-methyltransferase activity
KM843_RS12415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KM843_RS12440	COG0628	permease
KM843_RS12445	COG1126	abc transporter atp-binding protein
KM843_RS12450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM843_RS12455	COG0765	amino acid transport
KM843_RS12460	COG0765	amino acid transport
KM843_RS12475	COG3881	PFAM PRC-barrel domain
KM843_RS12480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KM843_RS12485	COG0457	Tetratricopeptide repeat
KM843_RS12495	COG1104	cysteine desulfurase activity
KM843_RS12500	COG1959	2 iron, 2 sulfur cluster binding
KM843_RS12505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KM843_RS12510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KM843_RS12535	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS12535	COG3103	Sh3 type 3 domain protein
KM843_RS12535	COG4991	sh3 domain protein
KM843_RS12545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KM843_RS12555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KM843_RS12555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KM843_RS12560	COG5416	Lipopolysaccharide assembly protein A domain
KM843_RS12565	COG0490	domain, Protein
KM843_RS12570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM843_RS12570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KM843_RS12580	COG2244	polysaccharide biosynthetic process
KM843_RS12585	COG2323	membrane
KM843_RS12595	COG1862	Preprotein translocase
KM843_RS12640	COG1388	LysM domain
KM843_RS12650	COG0157	Belongs to the NadC ModD family
KM843_RS12655	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KM843_RS12660	COG1104	cysteine desulfurase activity
KM843_RS12665	COG1827	regulation of RNA biosynthetic process
KM843_RS12670	COG0077	Prephenate dehydratase
KM843_RS12685	COG3290	protein histidine kinase activity
KM843_RS12690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KM843_RS12695	COG2868	ribosomal protein
KM843_RS12705	COG1994	Peptidase M50
KM843_RS12710	COG0739	heme binding
KM843_RS12715	COG2894	cell division
KM843_RS12725	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KM843_RS12735	COG1077	Cell shape determining protein MreB Mrl
KM843_RS12755	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KM843_RS12760	COG0285	dihydrofolate synthase activity
KM843_RS12765	COG0525	valine-tRNA ligase activity
KM843_RS12775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM843_RS12780	COG1388	LysM domain
KM843_RS12790	COG0113	porphobilinogen synthase activity
KM843_RS12795	COG1587	Uroporphyrinogen-III synthase
KM843_RS12805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KM843_RS12825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KM843_RS12830	COG0470	DNA polymerase III
KM843_RS12830	COG1067	ATP-dependent peptidase activity
KM843_RS12845	COG0457	Tetratricopeptide repeat
KM843_RS12845	COG1477	protein flavinylation
KM843_RS12860	COG0473	3-isopropylmalate dehydrogenase activity
KM843_RS12875	COG0440	acetolactate synthase activity
KM843_RS12880	COG0028	Belongs to the TPP enzyme family
KM843_RS12905	COG0622	Phosphoesterase
KM843_RS12910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KM843_RS12920	COG5401	PFAM Sporulation and spore germination
KM843_RS12930	COG1846	Transcriptional regulator
KM843_RS12935	COG2197	response regulator
KM843_RS12940	COG0824	Thioesterase
KM843_RS12945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KM843_RS12950	COG1053	succinate dehydrogenase
KM843_RS12955	COG2009	succinate dehydrogenase
KM843_RS12960	COG1719	4-vinyl reductase, 4VR
KM843_RS12965	COG0527	aspartate kinase activity
KM843_RS12975	COG3118	belongs to the thioredoxin family
KM843_RS12980	COG3534	alpha-L-arabinofuranosidase
KM843_RS12985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KM843_RS12990	COG2086	electron transfer activity
KM843_RS12995	COG1024	Enoyl-CoA hydratase
KM843_RS13000	COG1309	transcriptional regulator
KM843_RS13005	COG0318	PFAM AMP-dependent synthetase and ligase
KM843_RS13015	COG3766	membrane
KM843_RS13025	COG1796	DNA polymerase
KM843_RS13025	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM843_RS13030	COG1286	toxin biosynthetic process
KM843_RS13045	COG0072	phenylalanine-tRNA ligase activity
KM843_RS13045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM843_RS13050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KM843_RS13055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KM843_RS13065	COG3835	regulator
KM843_RS13070	COG0277	FAD linked oxidase domain protein
KM843_RS13075	COG0247	lactate metabolic process
KM843_RS13080	COG1966	Carbon starvation protein
KM843_RS13085	COG3534	alpha-L-arabinofuranosidase
KM843_RS13090	COG0395	ABC-type sugar transport system, permease component
KM843_RS13095	COG1175	transmembrane transport
KM843_RS13100	COG1653	transport
KM843_RS13110	COG0647	UMP catabolic process
KM843_RS13115	COG0235	Class ii aldolase
KM843_RS13120	COG1069	ribulokinase activity
KM843_RS13125	COG2160	L-arabinose isomerase activity
KM843_RS13130	COG3507	Belongs to the glycosyl hydrolase 43 family
KM843_RS13135	COG1363	Peptidase, m42
KM843_RS13145	COG3326	Membrane
KM843_RS13160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KM843_RS13165	COG1346	cytolysis
KM843_RS13170	COG1380	Effector of murein hydrolase LrgA
KM843_RS13175	COG3279	Response regulator of the LytR AlgR family
KM843_RS13180	COG3275	phosphorelay sensor kinase activity
KM843_RS13185	COG1011	Hydrolase
KM843_RS13200	COG0398	Pfam SNARE associated Golgi protein
KM843_RS13205	COG1484	DNA-dependent DNA replication
KM843_RS13210	COG3611	Membrane attachment protein
KM843_RS13225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM843_RS13230	COG1733	regulation of RNA biosynthetic process
KM843_RS13235	COG2814	Major facilitator Superfamily
KM843_RS13240	COG0656	L-ascorbic acid biosynthetic process
KM843_RS13245	COG0237	dephospho-CoA kinase activity
KM843_RS13250	COG1971	Probably functions as a manganese efflux pump
KM843_RS13255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KM843_RS13260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM843_RS13260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM843_RS13265	COG5002	protein histidine kinase activity
KM843_RS13270	COG0745	RESPONSE REGULATOR receiver
KM843_RS13280	COG0538	isocitrate dehydrogenase activity
KM843_RS13285	COG0372	Belongs to the citrate synthase family
KM843_RS13300	COG0628	permease
KM843_RS13305	COG3030	protein affecting phage T7 exclusion by the F plasmid
KM843_RS13310	COG0469	pyruvate kinase activity
KM843_RS13330	COG0281	malic enzyme
KM843_RS13335	COG0587	DNA-directed DNA polymerase activity
KM843_RS13355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KM843_RS13365	COG4109	DRTGG domain
KM843_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS13390	COG0521	Mo-molybdopterin cofactor biosynthetic process
KM843_RS13400	COG0827	DNA restriction-modification system
KM843_RS13405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KM843_RS13410	COG3874	Sporulation protein YtfJ
KM843_RS13420	COG1714	RDD family
KM843_RS13425	COG0616	signal peptide processing
KM843_RS13430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KM843_RS13435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KM843_RS13440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM843_RS13455	COG1104	cysteine desulfurase activity
KM843_RS13460	COG1114	Component of the transport system for branched-chain amino acids
KM843_RS13470	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KM843_RS13475	COG1309	transcriptional regulator
KM843_RS13480	COG1956	GAF domain-containing protein
KM843_RS13485	COG2199	diguanylate cyclase activity
KM843_RS13485	COG2203	Gaf domain
KM843_RS13495	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS13500	COG4282	regulation of fungal-type cell wall biogenesis
KM843_RS13525	COG1595	DNA-templated transcription, initiation
KM843_RS13550	COG1017	nitric oxide dioxygenase activity
KM843_RS13550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM843_RS13565	COG0693	protein deglycase activity
KM843_RS13580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KM843_RS13585	COG1378	Sugar-specific transcriptional regulator TrmB
KM843_RS13605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KM843_RS13610	COG0454	-acetyltransferase
KM843_RS13615	COG0517	IMP dehydrogenase activity
KM843_RS13620	COG0123	including yeast histone deacetylase and acetoin utilization protein
KM843_RS13625	COG1360	Flagellar Motor Protein
KM843_RS13630	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KM843_RS13635	COG1609	Transcriptional regulator
KM843_RS13640	COG1605	Chorismate mutase
KM843_RS13640	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KM843_RS13645	COG3118	belongs to the thioredoxin family
KM843_RS13650	COG4980	gas vesicle protein
KM843_RS13655	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KM843_RS13665	COG1674	ftsk spoiiie
KM843_RS13670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KM843_RS13680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS13690	COG1363	Peptidase, m42
KM843_RS13695	COG5584	Small secreted protein
KM843_RS13700	COG0281	malic enzyme
KM843_RS13705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KM843_RS13720	COG0510	thiamine kinase activity
KM843_RS13725	COG1597	lipid kinase activity
KM843_RS13735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KM843_RS13740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KM843_RS13745	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM843_RS13750	COG2252	PERMEase
KM843_RS13755	COG4473	ABC transporter
KM843_RS13760	COG1131	(ABC) transporter
KM843_RS13765	COG1349	DNA-binding transcription factor activity
KM843_RS13770	COG1187	pseudouridine synthase activity
KM843_RS13775	COG2244	polysaccharide biosynthetic process
KM843_RS13780	COG2081	HI0933 family
KM843_RS13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KM843_RS13795	COG1609	Transcriptional regulator
KM843_RS13800	COG1653	transport
KM843_RS13805	COG1175	transmembrane transport
KM843_RS13810	COG0395	ABC-type sugar transport system, permease component
KM843_RS13815	COG1486	melibiose metabolic process
KM843_RS13825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KM843_RS13840	COG1366	Belongs to the anti-sigma-factor antagonist family
KM843_RS13840	COG2202	Pas domain
KM843_RS13845	COG2814	Major facilitator Superfamily
KM843_RS13850	COG5522	Integral membrane protein (intg_mem_TP0381)
KM843_RS13855	COG0577	efflux transmembrane transporter activity
KM843_RS13860	COG1136	(ABC) transporter
KM843_RS13865	COG2205	protein histidine kinase activity
KM843_RS13870	COG0745	RESPONSE REGULATOR receiver
KM843_RS13875	COG0577	efflux transmembrane transporter activity
KM843_RS13880	COG1136	(ABC) transporter
KM843_RS13900	COG1131	(ABC) transporter
KM843_RS13905	COG1725	Transcriptional regulator
KM843_RS13920	COG0640	Transcriptional regulator
KM843_RS13945	COG0477	Major facilitator Superfamily
KM843_RS13950	COG1242	4 iron, 4 sulfur cluster binding
KM843_RS13955	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KM843_RS13965	COG0584	glycerophosphoryl diester phosphodiesterase
KM843_RS13975	COG2267	carboxylic ester hydrolase activity
KM843_RS13980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KM843_RS13985	COG1113	amino acid transport
KM843_RS13990	COG0367	asparagine synthase
KM843_RS14010	COG1506	peptidase
KM843_RS14015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KM843_RS14020	COG1116	anion transmembrane transporter activity
KM843_RS14025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KM843_RS14030	COG0494	nUDIX hydrolase
KM843_RS14035	COG4824	toxin secretion phage lysis holin
KM843_RS14040	COG0783	Belongs to the Dps family
KM843_RS14065	COG0288	reversible hydration of carbon dioxide
KM843_RS14075	COG1271	oxidase subunit
KM843_RS14080	COG1294	oxidase, subunit
KM843_RS14090	COG4948	Mandelate Racemase Muconate Lactonizing
KM843_RS14100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KM843_RS14105	COG0596	Alpha beta hydrolase
KM843_RS14115	COG1169	isochorismate synthase
KM843_RS14120	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KM843_RS14125	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KM843_RS14250	COG3859	Proton-coupled thiamine transporter YuaJ
KM843_RS14255	COG2268	Band 7 protein
KM843_RS14260	COG1585	Membrane protein implicated in regulation of membrane protease activity
KM843_RS14265	COG2318	DinB family
KM843_RS14275	COG1454	alcohol dehydrogenase
KM843_RS14280	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS14285	COG1510	regulation of RNA biosynthetic process
KM843_RS14295	COG0569	domain protein
KM843_RS14300	COG1705	Flagellar rod assembly protein muramidase FlgJ
KM843_RS14305	COG1017	nitric oxide dioxygenase activity
KM843_RS14305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KM843_RS14330	COG0628	permease
KM843_RS14335	COG0673	inositol 2-dehydrogenase activity
KM843_RS14340	COG0693	protein deglycase activity
KM843_RS14345	COG0840	transmembrane signaling receptor activity
KM843_RS14350	COG0840	transmembrane signaling receptor activity
KM843_RS14355	COG0840	transmembrane signaling receptor activity
KM843_RS14360	COG0840	transmembrane signaling receptor activity
KM843_RS14375	COG2070	2-Nitropropane dioxygenase
KM843_RS14380	COG0432	Pfam Uncharacterised protein family UPF0047
KM843_RS14385	COG0366	Alpha amylase catalytic
KM843_RS14390	COG1253	flavin adenine dinucleotide binding
KM843_RS14395	COG2738	Putative neutral zinc metallopeptidase
KM843_RS14410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KM843_RS14435	COG1335	isochorismatase
KM843_RS14440	COG1979	alcohol dehydrogenase
KM843_RS14445	COG1979	alcohol dehydrogenase
KM843_RS14450	COG2155	Conserved Protein
KM843_RS14455	COG1098	S1 RNA binding domain
KM843_RS14460	COG0436	Aminotransferase
KM843_RS14465	COG1522	sequence-specific DNA binding
KM843_RS14470	COG2267	carboxylic ester hydrolase activity
KM843_RS14480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KM843_RS14485	COG2205	protein histidine kinase activity
KM843_RS14495	COG5018	Exonuclease
KM843_RS14500	COG2814	Major facilitator Superfamily
KM843_RS14505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM843_RS14510	COG3011	Protein conserved in bacteria
KM843_RS14520	COG3290	protein histidine kinase activity
KM843_RS14525	COG4565	transcriptional regulatory protein
KM843_RS14530	COG1744	ABC transporter substrate-binding protein PnrA-like
KM843_RS14535	COG3845	ABC transporter
KM843_RS14540	COG4603	Belongs to the binding-protein-dependent transport system permease family
KM843_RS14545	COG1079	Belongs to the binding-protein-dependent transport system permease family
KM843_RS14555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KM843_RS14555	COG2111	Na H antiporter
KM843_RS14560	COG2111	Na H antiporter
KM843_RS14565	COG1006	Multisubunit Na H antiporter MnhC subunit
KM843_RS14570	COG0651	ATP synthesis coupled electron transport
KM843_RS14575	COG1863	multisubunit Na H antiporter MnhE subunit
KM843_RS14580	COG2212	antiporter activity
KM843_RS14585	COG1320	monovalent cation:proton antiporter activity
KM843_RS14590	COG2050	protein possibly involved in aromatic compounds catabolism
KM843_RS14595	COG2197	response regulator
KM843_RS14600	COG4585	Histidine kinase
KM843_RS14625	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KM843_RS14630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KM843_RS14635	COG1335	isochorismatase
KM843_RS14640	COG5506	Protein of unknown function (DUF1694)
KM843_RS14655	COG0628	permease
KM843_RS14665	COG1418	mRNA catabolic process
KM843_RS14670	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS14680	COG1511	domain protein
KM843_RS14685	COG1674	ftsk spoiiie
KM843_RS14685	COG0433	COG0433 Predicted ATPase
KM843_RS14690	COG4499	WXG100 protein secretion system (Wss), protein YukC
KM843_RS14695	COG5417	Belongs to the EsaB family
KM843_RS14700	COG4842	Belongs to the WXG100 family
KM843_RS14705	COG2508	Transcriptional regulator
KM843_RS14705	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KM843_RS14710	COG0686	Belongs to the AlaDH PNT family
KM843_RS14715	COG5634	Uncharacterized conserved protein (DUF2278)
KM843_RS14720	COG3251	PFAM MbtH domain protein
KM843_RS14725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS14730	COG1535	isochorismatase
KM843_RS14730	COG3433	isochorismatase activity
KM843_RS14735	COG1021	2,3-dihydroxybenzoate-AMP ligase
KM843_RS14740	COG1169	isochorismate synthase
KM843_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS14750	COG2819	hydrolase of the alpha beta superfamily
KM843_RS14755	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KM843_RS14760	COG1268	BioY protein
KM843_RS14765	COG2056	Na+-H+ antiporter family
KM843_RS14775	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KM843_RS14780	COG3584	3D domain protein
KM843_RS14795	COG1252	NADH dehydrogenase
KM843_RS14825	COG1131	(ABC) transporter
KM843_RS14845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KM843_RS14850	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KM843_RS14855	COG0316	Belongs to the HesB IscA family
KM843_RS14865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM843_RS14875	COG1252	NADH dehydrogenase
KM843_RS14880	COG4837	Protein of unknown function (DUF1462)
KM843_RS14885	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KM843_RS14890	COG0823	Involved in the tonB-independent uptake of proteins
KM843_RS14890	COG1506	peptidase
KM843_RS14890	COG4946	Tricorn protease homolog
KM843_RS14900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KM843_RS14905	COG0460	homoserine dehydrogenase
KM843_RS14910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KM843_RS14915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KM843_RS14920	COG0647	UMP catabolic process
KM843_RS14925	COG2445	Protein of unknown function DUF86
KM843_RS14930	COG4470	Protein conserved in bacteria
KM843_RS14940	COG0739	heme binding
KM843_RS14950	COG0737	Belongs to the 5'-nucleotidase family
KM843_RS14955	COG0730	response to heat
KM843_RS14960	COG1801	Protein of unknown function DUF72
KM843_RS14975	COG2508	Transcriptional regulator
KM843_RS14985	COG2814	Major facilitator Superfamily
KM843_RS14990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KM843_RS14995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KM843_RS15000	COG2356	endonuclease I
KM843_RS15005	COG3842	ATPase activity
KM843_RS15010	COG2188	Transcriptional regulator
KM843_RS15015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM843_RS15020	COG0395	ABC-type sugar transport system, permease component
KM843_RS15025	COG1175	transmembrane transport
KM843_RS15030	COG1653	transport
KM843_RS15035	COG2222	sugar isomerase
KM843_RS15040	COG0789	Transcriptional regulator
KM843_RS15055	COG0322	excinuclease ABC activity
KM843_RS15060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KM843_RS15065	COG2226	methyltransferase
KM843_RS15075	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS15080	COG0719	Fe-S assembly protein
KM843_RS15085	COG0822	iron-sulfur transferase activity
KM843_RS15090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KM843_RS15095	COG0719	Fe-S assembly protein
KM843_RS15100	COG0396	ATPase activity
KM843_RS15110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM843_RS15115	COG1464	Belongs to the NlpA lipoprotein family
KM843_RS15120	COG2011	ABC-type metal ion transport system permease component
KM843_RS15125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KM843_RS15135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KM843_RS15140	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KM843_RS15155	COG1393	Belongs to the ArsC family
KM843_RS15160	COG1960	acyl-CoA dehydrogenase activity
KM843_RS15165	COG0183	Belongs to the thiolase family
KM843_RS15170	COG1024	Enoyl-CoA hydratase
KM843_RS15170	COG1250	3-hydroxyacyl-CoA dehydrogenase
KM843_RS15190	COG5577	PFAM Coat F domain
KM843_RS15195	COG1846	Transcriptional regulator
KM843_RS15200	COG0477	Major facilitator Superfamily
KM843_RS15205	COG1942	4-Oxalocrotonate Tautomerase
KM843_RS15210	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS15215	COG0583	DNA-binding transcription factor activity
KM843_RS15225	COG0583	DNA-binding transcription factor activity
KM843_RS15245	COG1120	ATPase activity
KM843_RS15260	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS15265	COG0783	Belongs to the Dps family
KM843_RS15270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM843_RS15275	COG0745	RESPONSE REGULATOR receiver
KM843_RS15280	COG2205	protein histidine kinase activity
KM843_RS15280	COG2770	Histidine kinase
KM843_RS15290	COG1309	transcriptional regulator
KM843_RS15295	COG0114	fumarate hydratase activity
KM843_RS15305	COG0697	spore germination
KM843_RS15310	COG0814	amino acid
KM843_RS15320	COG2197	response regulator
KM843_RS15325	COG4585	Histidine kinase
KM843_RS15330	COG4758	membrane
KM843_RS15335	COG3595	metallopeptidase activity
KM843_RS15340	COG1842	Phage shock protein A
KM843_RS15345	COG4758	membrane
KM843_RS15350	COG2814	Major facilitator Superfamily
KM843_RS15355	COG2096	Adenosyltransferase
KM843_RS15360	COG1120	ATPase activity
KM843_RS15365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS15370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM843_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS15380	COG3386	PFAM SMP-30 Gluconolaconase
KM843_RS15385	COG2205	protein histidine kinase activity
KM843_RS15390	COG0745	RESPONSE REGULATOR receiver
KM843_RS15400	COG1191	sigma factor activity
KM843_RS15410	COG2140	Oxalate decarboxylase
KM843_RS15420	COG1120	ATPase activity
KM843_RS15425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS15430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS15435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM843_RS15440	COG0531	amino acid
KM843_RS15450	COG1988	membrane-bound metal-dependent
KM843_RS15455	COG1368	sulfuric ester hydrolase activity
KM843_RS15460	COG1910	domain protein
KM843_RS15465	COG0725	ABC transporter, periplasmic molybdate-binding protein
KM843_RS15470	COG4149	molybdate abc transporter
KM843_RS15475	COG2197	response regulator
KM843_RS15480	COG3850	Histidine kinase
KM843_RS15485	COG1131	(ABC) transporter
KM843_RS15495	COG0842	Transport permease protein
KM843_RS15500	COG0656	L-ascorbic acid biosynthetic process
KM843_RS15520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KM843_RS15525	COG3973	AAA domain
KM843_RS15530	COG2860	membrane
KM843_RS15540	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KM843_RS15545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KM843_RS15550	COG2217	Heavy metal translocating P-type atpase
KM843_RS15555	COG2217	Heavy metal translocating P-type atpase
KM843_RS15560	COG2608	mercury ion transmembrane transporter activity
KM843_RS15565	COG1937	Protein conserved in bacteria
KM843_RS15570	COG0673	inositol 2-dehydrogenase activity
KM843_RS15585	COG2814	Major facilitator Superfamily
KM843_RS15600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS15605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KM843_RS15610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS15615	COG1126	abc transporter atp-binding protein
KM843_RS15620	COG0765	amino acid transport
KM843_RS15625	COG0765	amino acid transport
KM843_RS15630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KM843_RS15640	COG0454	-acetyltransferase
KM843_RS15645	COG0583	DNA-binding transcription factor activity
KM843_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS15655	COG2732	(Barnase) inhibitor
KM843_RS15670	COG0557	exoribonuclease II activity
KM843_RS15675	COG1647	Serine aminopeptidase, S33
KM843_RS15680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KM843_RS15685	COG1476	TRANSCRIPTIONal
KM843_RS15690	COG1396	sequence-specific DNA binding
KM843_RS15695	COG1396	sequence-specific DNA binding
KM843_RS15700	COG1733	regulation of RNA biosynthetic process
KM843_RS15725	COG1131	(ABC) transporter
KM843_RS15730	COG1174	glycine betaine transport
KM843_RS15735	COG1732	Glycine betaine
KM843_RS15740	COG1174	glycine betaine transport
KM843_RS15745	COG0517	IMP dehydrogenase activity
KM843_RS15745	COG1125	glycine betaine transport
KM843_RS15750	COG1510	regulation of RNA biosynthetic process
KM843_RS15755	COG1174	glycine betaine transport
KM843_RS15760	COG1732	Glycine betaine
KM843_RS15765	COG1174	glycine betaine transport
KM843_RS15770	COG1125	glycine betaine transport
KM843_RS15770	COG0517	IMP dehydrogenase activity
KM843_RS15775	COG1510	regulation of RNA biosynthetic process
KM843_RS15780	COG2095	MarC family integral membrane protein
KM843_RS15785	COG3064	Membrane
KM843_RS15790	COG4640	response to antibiotic
KM843_RS15795	COG0456	acetyltransferase
KM843_RS15810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KM843_RS15825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM843_RS15830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KM843_RS15835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM843_RS15845	COG2234	aminopeptidase activity
KM843_RS15865	COG0126	phosphoglycerate kinase activity
KM843_RS15870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KM843_RS15875	COG2390	Transcriptional regulator
KM843_RS15880	COG2814	Major facilitator Superfamily
KM843_RS15885	COG1609	Transcriptional regulator
KM843_RS15890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS15900	COG0583	DNA-binding transcription factor activity
KM843_RS15905	COG0697	spore germination
KM843_RS15910	COG1113	amino acid transport
KM843_RS15920	COG1609	Transcriptional regulator
KM843_RS15930	COG0561	phosphatase activity
KM843_RS15935	COG1737	Transcriptional regulator
KM843_RS15940	COG1070	Carbohydrate kinase
KM843_RS15965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KM843_RS15970	COG2186	Transcriptional regulator
KM843_RS15975	COG1620	l-lactate permease
KM843_RS15980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KM843_RS15990	COG5039	Polysaccharide pyruvyl transferase
KM843_RS15995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM843_RS16000	COG0110	maltose O-acetyltransferase activity
KM843_RS16005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KM843_RS16010	COG2244	polysaccharide biosynthetic process
KM843_RS16015	COG1216	Glycosyl transferase, family 2
KM843_RS16020	COG5039	Polysaccharide pyruvyl transferase
KM843_RS16025	COG1216	Glycosyl transferase, family 2
KM843_RS16035	COG0438	transferase activity, transferring glycosyl groups
KM843_RS16040	COG1215	transferase activity, transferring glycosyl groups
KM843_RS16045	COG0438	transferase activity, transferring glycosyl groups
KM843_RS16050	COG1086	Polysaccharide biosynthesis protein
KM843_RS16055	COG0489	protein tyrosine kinase activity
KM843_RS16060	COG3944	biosynthesis protein
KM843_RS16065	COG1396	sequence-specific DNA binding
KM843_RS16070	COG2272	Belongs to the type-B carboxylesterase lipase family
KM843_RS16075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KM843_RS16080	COG2364	Membrane
KM843_RS16085	COG0456	acetyltransferase
KM843_RS16090	COG3479	Phenolic acid decarboxylase
KM843_RS16140	COG2223	nitrite transmembrane transporter activity
KM843_RS16145	COG1609	Transcriptional regulator
KM843_RS16155	COG0583	DNA-binding transcription factor activity
KM843_RS16160	COG2828	Protein conserved in bacteria
KM843_RS16165	COG0477	Major facilitator Superfamily
KM843_RS16165	COG2814	Major facilitator Superfamily
KM843_RS16170	COG1611	Belongs to the LOG family
KM843_RS16175	COG1694	Mazg nucleotide pyrophosphohydrolase
KM843_RS16180	COG0659	secondary active sulfate transmembrane transporter activity
KM843_RS16185	COG0288	reversible hydration of carbon dioxide
KM843_RS16190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KM843_RS16195	COG4290	ribonuclease
KM843_RS16200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KM843_RS16205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS16215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KM843_RS16225	COG1051	belongs to the nudix hydrolase family
KM843_RS16230	COG0492	ferredoxin-NADP+ reductase activity
KM843_RS16235	COG3883	PFAM NLP P60 protein
KM843_RS16235	COG0791	NLP P60 protein
KM843_RS16240	COG0457	Tetratricopeptide repeat
KM843_RS16245	COG5002	protein histidine kinase activity
KM843_RS16250	COG0745	RESPONSE REGULATOR receiver
KM843_RS16255	COG1132	(ABC) transporter
KM843_RS16260	COG0140	phosphoribosyl-ATP diphosphatase activity
KM843_RS16260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KM843_RS16285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KM843_RS16300	COG4990	cell redox homeostasis
KM843_RS16305	COG0110	maltose O-acetyltransferase activity
KM843_RS16325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KM843_RS16335	COG2188	Transcriptional regulator
KM843_RS16340	COG1309	transcriptional regulator
KM843_RS16345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KM843_RS16350	COG1950	PFAM Membrane protein of
KM843_RS16355	COG1983	PspC domain protein
KM843_RS16360	COG3595	metallopeptidase activity
KM843_RS16375	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KM843_RS16385	COG4897	Protein conserved in bacteria
KM843_RS16390	COG3848	Pyruvate phosphate dikinase
KM843_RS16390	COG0574	Belongs to the PEP-utilizing enzyme family
KM843_RS16395	COG1309	transcriptional regulator
KM843_RS16400	COG2814	Major facilitator Superfamily
KM843_RS16405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM843_RS16415	COG0793	Belongs to the peptidase S41A family
KM843_RS16415	COG3409	Peptidoglycan-binding domain 1 protein
KM843_RS16420	COG3420	alginic acid biosynthetic process
KM843_RS16425	COG2177	Part of the ABC transporter FtsEX involved in
KM843_RS16430	COG2884	Cell division ATP-binding protein ftsE
KM843_RS16435	COG2010	Cytochrome c
KM843_RS16440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS16455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KM843_RS16470	COG1516	flagellar protein fliS
KM843_RS16475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KM843_RS16480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM843_RS16500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KM843_RS16505	COG1256	bacterial-type flagellum assembly
KM843_RS16505	COG4786	Flagellar basal body rod
KM843_RS16510	COG3418	PFAM FlgN family protein
KM843_RS16515	COG2747	anti-sigma28 factor FlgM
KM843_RS16525	COG1040	competence protein
KM843_RS16535	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KM843_RS16540	COG1307	EDD domain protein, DegV family
KM843_RS16545	COG2197	response regulator
KM843_RS16550	COG4585	Histidine kinase
KM843_RS16555	COG1739	Uncharacterized protein family UPF0029
KM843_RS16560	COG1316	TRANSCRIPTIONal
KM843_RS16565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KM843_RS16570	COG0438	transferase activity, transferring glycosyl groups
KM843_RS16575	COG1215	transferase activity, transferring glycosyl groups
KM843_RS16580	COG3206	protein involved in exopolysaccharide biosynthesis
KM843_RS16585	COG3307	-O-antigen
KM843_RS16590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM843_RS16595	COG0297	glycogen (starch) synthase activity
KM843_RS16595	COG0438	transferase activity, transferring glycosyl groups
KM843_RS16600	COG2244	polysaccharide biosynthetic process
KM843_RS16610	COG0860	N-Acetylmuramoyl-L-alanine amidase
KM843_RS16610	COG2247	cell wall binding repeat
KM843_RS16615	COG2247	cell wall binding repeat
KM843_RS16615	COG2385	sporulation resulting in formation of a cellular spore
KM843_RS16625	COG1316	TRANSCRIPTIONal
KM843_RS16630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KM843_RS16635	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KM843_RS16640	COG1134	teichoic acid transport
KM843_RS16645	COG1682	transport, permease protein
KM843_RS16650	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KM843_RS16660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KM843_RS16665	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KM843_RS16670	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KM843_RS16675	COG4193	domain, Protein
KM843_RS16680	COG1482	cell wall glycoprotein biosynthetic process
KM843_RS16685	COG0697	spore germination
KM843_RS16690	COG0814	amino acid
KM843_RS16700	COG1215	transferase activity, transferring glycosyl groups
KM843_RS16705	COG2814	Major facilitator Superfamily
KM843_RS16710	COG1316	TRANSCRIPTIONal
KM843_RS16715	COG0561	phosphatase activity
KM843_RS16720	COG2433	Pfam Transposase IS66
KM843_RS16725	COG0791	NLP P60 protein
KM843_RS16735	COG2843	Capsule synthesis protein
KM843_RS16745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KM843_RS16750	COG0697	spore germination
KM843_RS16755	COG0814	amino acid
KM843_RS16765	COG1609	Transcriptional regulator
KM843_RS16770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KM843_RS16780	COG1129	ABC transporter
KM843_RS16785	COG1172	Belongs to the binding-protein-dependent transport system permease family
KM843_RS16790	COG1879	ABC-type sugar transport system periplasmic component
KM843_RS16795	COG3103	Sh3 type 3 domain protein
KM843_RS16800	COG2249	NAD(P)H dehydrogenase (quinone) activity
KM843_RS16805	COG3527	Alpha-acetolactate decarboxylase
KM843_RS16810	COG0028	Belongs to the TPP enzyme family
KM843_RS16815	COG0583	DNA-binding transcription factor activity
KM843_RS16820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM843_RS16835	COG5337	Spore coat protein CotH
KM843_RS16845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KM843_RS16855	COG0405	Gamma-glutamyltransferase
KM843_RS16860	COG1522	sequence-specific DNA binding
KM843_RS16865	COG2059	Chromate
KM843_RS16870	COG2059	Chromate
KM843_RS16925	COG5444	nuclease activity
KM843_RS16940	COG3878	Protein conserved in bacteria
KM843_RS16945	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KM843_RS16950	COG4464	protein tyrosine phosphatase activity
KM843_RS16955	COG0489	protein tyrosine kinase activity
KM843_RS16960	COG3944	biosynthesis protein
KM843_RS16970	COG4715	Zinc finger, swim domain protein
KM843_RS16975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KM843_RS16980	COG0561	phosphatase activity
KM843_RS16985	COG1349	DNA-binding transcription factor activity
KM843_RS16990	COG0629	single-stranded DNA binding
KM843_RS17015	COG0457	Tetratricopeptide repeat
KM843_RS17020	COG4786	Flagellar basal body rod
KM843_RS17025	COG4786	Flagellar basal body rod
KM843_RS17030	COG1077	Cell shape determining protein MreB Mrl
KM843_RS17035	COG1609	Transcriptional regulator
KM843_RS17040	COG1846	Transcriptional regulator
KM843_RS17045	COG2814	Major facilitator Superfamily
KM843_RS17050	COG1953	Uracil, thiamine, allantoin
KM843_RS17055	COG0477	Major facilitator Superfamily
KM843_RS17060	COG1335	isochorismatase
KM843_RS17065	COG0004	ammonium transporteR
KM843_RS17070	COG0347	Belongs to the P(II) protein family
KM843_RS17075	COG0772	Belongs to the SEDS family
KM843_RS17080	COG0671	phosphoesterase, PA-phosphatase related
KM843_RS17090	COG0739	heme binding
KM843_RS17095	COG1247	-acetyltransferase
KM843_RS17110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM843_RS17120	COG0726	polysaccharide deacetylase
KM843_RS17125	COG1959	2 iron, 2 sulfur cluster binding
KM843_RS17140	COG0831	urea catabolic process
KM843_RS17145	COG3237	CsbD-like
KM843_RS17150	COG1994	Peptidase M50
KM843_RS17155	COG0457	Tetratricopeptide repeat
KM843_RS17165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KM843_RS17175	COG2304	oxidoreductase activity
KM843_RS17180	COG2304	oxidoreductase activity
KM843_RS17185	COG2385	sporulation resulting in formation of a cellular spore
KM843_RS17190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KM843_RS17200	COG4836	Membrane
KM843_RS17270	COG0698	ribose 5-phosphate isomerase
KM843_RS17275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KM843_RS17285	COG0009	L-threonylcarbamoyladenylate synthase
KM843_RS17290	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KM843_RS17310	COG2890	protein-(glutamine-N5) methyltransferase activity
KM843_RS17315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KM843_RS17320	COG0346	lactoylglutathione lyase activity
KM843_RS17325	COG0789	Transcriptional regulator
KM843_RS17330	COG0679	Auxin Efflux Carrier
KM843_RS17335	COG0281	malic enzyme
KM843_RS17350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KM843_RS17355	COG1494	fructose-1,6-bisphosphatase
KM843_RS17360	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KM843_RS17370	COG0191	fructose-bisphosphate aldolase activity
KM843_RS17375	COG2204	response regulator
KM843_RS17380	COG4821	SIS domain
KM843_RS17395	COG0247	lactate metabolic process
KM843_RS17395	COG2181	nitrate reductase activity
KM843_RS17400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM843_RS17415	COG1132	(ABC) transporter
KM843_RS17420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KM843_RS17430	COG2181	nitrate reductase activity
KM843_RS17435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KM843_RS17440	COG1140	nitrate reductase beta subunit
KM843_RS17445	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KM843_RS17450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM843_RS17460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KM843_RS17465	COG2223	nitrite transmembrane transporter activity
KM843_RS17475	COG4506	Protein conserved in bacteria
KM843_RS17485	COG3391	amine dehydrogenase activity
KM843_RS17490	COG3391	amine dehydrogenase activity
KM843_RS17495	COG0457	Tetratricopeptide repeat
KM843_RS17535	COG0010	Belongs to the arginase family
KM843_RS17540	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KM843_RS17545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KM843_RS17560	COG1994	Peptidase M50
KM843_RS17565	COG1942	4-Oxalocrotonate Tautomerase
KM843_RS17570	COG1846	Transcriptional regulator
KM843_RS17575	COG0531	amino acid
KM843_RS17580	COG3465	dGTPase activity
KM843_RS17585	COG1078	dGTPase activity
KM843_RS17600	COG1695	Transcriptional regulator
KM843_RS17610	COG1131	(ABC) transporter
KM843_RS17615	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KM843_RS17645	COG0583	DNA-binding transcription factor activity
KM843_RS17650	COG2855	membrane
KM843_RS17655	COG0280	phosphate acetyltransferase
KM843_RS17665	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS17670	COG0436	Aminotransferase
KM843_RS17700	COG2814	Major facilitator Superfamily
KM843_RS17705	COG2814	Major facilitator Superfamily
KM843_RS17710	COG0833	amino acid
KM843_RS17715	COG4187	Peptidase family M20/M25/M40
KM843_RS17720	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS17725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KM843_RS17730	COG2205	protein histidine kinase activity
KM843_RS17735	COG0745	RESPONSE REGULATOR receiver
KM843_RS17750	COG1131	(ABC) transporter
KM843_RS17755	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KM843_RS17760	COG1091	dTDP-4-dehydrorhamnose reductase activity
KM843_RS17765	COG1088	dTDP-glucose 4,6-dehydratase activity
KM843_RS17770	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KM843_RS17775	COG3980	spore coat polysaccharide biosynthesis protein
KM843_RS17780	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
KM843_RS17785	COG2089	acid synthase
KM843_RS17790	COG0456	acetyltransferase
KM843_RS17795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KM843_RS17800	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KM843_RS17805	COG0463	Glycosyl transferase, family 2
KM843_RS17815	COG2363	Small membrane protein
KM843_RS17820	COG2233	PERMEase
KM843_RS17835	COG1216	Glycosyl transferase, family 2
KM843_RS17850	COG1695	Transcriptional regulator
KM843_RS17855	COG0351	phosphomethylpyrimidine kinase
KM843_RS17865	COG1621	beta-fructofuranosidase activity
KM843_RS17870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS17870	COG1263	PTS System
KM843_RS17875	COG3711	transcriptional antiterminator
KM843_RS17885	COG1404	Belongs to the peptidase S8 family
KM843_RS17890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KM843_RS17900	COG0778	Nitroreductase
KM843_RS17905	COG0772	Belongs to the SEDS family
KM843_RS17910	COG0454	-acetyltransferase
KM843_RS17930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KM843_RS17935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KM843_RS17940	COG2261	transglycosylase associated protein
KM843_RS17945	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KM843_RS17950	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KM843_RS17955	COG2246	polysaccharide biosynthetic process
KM843_RS17960	COG1309	transcriptional regulator
KM843_RS17980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KM843_RS17985	COG2837	iron assimilation
KM843_RS18005	COG0583	DNA-binding transcription factor activity
KM843_RS18015	COG1346	cytolysis
KM843_RS18020	COG4895	conserved protein (DUF2196)
KM843_RS18025	COG0789	Transcriptional regulator
KM843_RS18030	COG5504	Zn-dependent protease
KM843_RS18035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KM843_RS18040	COG0346	lactoylglutathione lyase activity
KM843_RS18045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS18050	COG1404	Belongs to the peptidase S8 family
KM843_RS18055	COG1442	glycosyl transferase family 8
KM843_RS18060	COG2357	RelA SpoT domain protein
KM843_RS18065	COG1575	Belongs to the MenA family. Type 1 subfamily
KM843_RS18080	COG1696	Membrane protein involved in D-alanine export
KM843_RS18090	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KM843_RS18095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KM843_RS18100	COG1486	melibiose metabolic process
KM843_RS18105	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM843_RS18110	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS18115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS18120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KM843_RS18120	COG3711	transcriptional antiterminator
KM843_RS18130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS18135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KM843_RS18145	COG0640	Transcriptional regulator
KM843_RS18150	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KM843_RS18155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS18160	COG1447	Phosphotransferase system cellobiose-specific component IIA
KM843_RS18165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KM843_RS18170	COG2723	6-phospho-beta-galactosidase activity
KM843_RS18175	COG1940	carbohydrate kinase activity
KM843_RS18180	COG1482	cell wall glycoprotein biosynthetic process
KM843_RS18190	COG0753	catalase activity
KM843_RS18195	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KM843_RS18200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KM843_RS18205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KM843_RS18210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KM843_RS18215	COG4988	ABC transporter
KM843_RS18220	COG1294	oxidase, subunit
KM843_RS18225	COG1271	oxidase subunit
KM843_RS18230	COG3493	citrate carrier protein
KM843_RS18235	COG0726	polysaccharide deacetylase
KM843_RS18240	COG3842	ATPase activity
KM843_RS18245	COG2508	Transcriptional regulator
KM843_RS18250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS18260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KM843_RS18275	COG4894	glucomannan catabolic process
KM843_RS18280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KM843_RS18285	COG0500	methyltransferase
KM843_RS18290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM843_RS18305	COG0753	catalase activity
KM843_RS18305	COG0693	protein deglycase activity
KM843_RS18310	COG2851	Citrate transporter
KM843_RS18315	COG2273	Hydrolase Family 16
KM843_RS18320	COG3711	transcriptional antiterminator
KM843_RS18325	COG2270	Major facilitator Superfamily
KM843_RS18330	COG0513	Belongs to the DEAD box helicase family
KM843_RS18380	COG0697	spore germination
KM843_RS18385	COG0589	response to stress
KM843_RS18390	COG2723	6-phospho-beta-galactosidase activity
KM843_RS18395	COG1263	PTS System
KM843_RS18395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KM843_RS18395	COG2190	(PTS) system
KM843_RS18405	COG0494	nUDIX hydrolase
KM843_RS18410	COG3507	Belongs to the glycosyl hydrolase 43 family
KM843_RS18435	COG0010	Belongs to the arginase family
KM843_RS18440	COG0833	amino acid
KM843_RS18445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KM843_RS18450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KM843_RS18460	COG2390	Transcriptional regulator
KM843_RS18465	COG0561	phosphatase activity
KM843_RS18495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KM843_RS18505	COG5294	Protein conserved in bacteria
KM843_RS18510	COG0577	efflux transmembrane transporter activity
KM843_RS18515	COG1136	(ABC) transporter
KM843_RS18520	COG2205	protein histidine kinase activity
KM843_RS18525	COG0745	RESPONSE REGULATOR receiver
KM843_RS18530	COG2205	protein histidine kinase activity
KM843_RS18535	COG0745	RESPONSE REGULATOR receiver
KM843_RS18565	COG1082	Xylose isomerase domain protein TIM barrel
KM843_RS18575	COG2814	Major facilitator Superfamily
KM843_RS18605	COG1349	DNA-binding transcription factor activity
KM843_RS18610	COG0667	Aldo Keto reductase
KM843_RS18615	COG2814	Major facilitator Superfamily
KM843_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS18630	COG2197	response regulator
KM843_RS18635	COG4585	Histidine kinase
KM843_RS18640	COG3239	Fatty acid desaturase
KM843_RS18645	COG1309	transcriptional regulator
KM843_RS18650	COG1012	belongs to the aldehyde dehydrogenase family
KM843_RS18655	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KM843_RS18665	COG0640	Transcriptional regulator
KM843_RS18670	COG2814	Major facilitator Superfamily
KM843_RS18675	COG1714	RDD family
KM843_RS18685	COG0450	alkyl hydroperoxide reductase
KM843_RS18690	COG3634	alkyl hydroperoxide reductase activity
KM843_RS18695	COG3177	Filamentation induced by cAMP protein fic
KM843_RS18700	COG1113	amino acid transport
KM843_RS18710	COG2080	2 iron, 2 sulfur cluster binding
KM843_RS18725	COG2068	MobA-Related Protein
KM843_RS18730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KM843_RS18795	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KM843_RS18800	COG0667	Aldo Keto reductase
KM843_RS18805	COG0456	acetyltransferase
KM843_RS18810	COG0457	Tetratricopeptide repeat
KM843_RS18815	COG0010	Belongs to the arginase family
KM843_RS18820	COG0833	amino acid
KM843_RS18825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KM843_RS18830	COG3829	transcription factor binding
KM843_RS18840	COG0488	(ABC) transporter
KM843_RS18855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KM843_RS18860	COG3850	Histidine kinase
KM843_RS18860	COG5002	protein histidine kinase activity
KM843_RS18865	COG0745	RESPONSE REGULATOR receiver
KM843_RS18870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KM843_RS18875	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KM843_RS18880	COG4853	Protein conserved in bacteria
KM843_RS18885	COG4863	YycH protein
KM843_RS18890	COG5002	protein histidine kinase activity
KM843_RS18895	COG0745	RESPONSE REGULATOR receiver
KM843_RS18925	COG0346	lactoylglutathione lyase activity
KM843_RS18930	COG0305	Participates in initiation and elongation during chromosome replication
KM843_RS18945	COG3093	addiction module antidote protein HigA
KM843_RS18950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KM843_RS18965	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KM843_RS18970	COG0438	transferase activity, transferring glycosyl groups
KM843_RS18990	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KM843_RS18995	COG4241	membrane
KM843_RS19005	COG5577	PFAM Coat F domain
KM843_RS19010	COG1733	regulation of RNA biosynthetic process
KM843_RS19020	COG0697	spore germination
KM843_RS19025	COG1621	beta-fructofuranosidase activity
KM843_RS19030	COG1621	beta-fructofuranosidase activity
KM843_RS19035	COG1802	Transcriptional regulator
KM843_RS19040	COG2318	DinB family
KM843_RS19050	COG0583	DNA-binding transcription factor activity
KM843_RS19060	COG2814	Major facilitator Superfamily
KM843_RS19065	COG0583	DNA-binding transcription factor activity
KM843_RS19075	COG0778	Nitroreductase
KM843_RS19080	COG1846	Transcriptional regulator
KM843_RS19085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KM843_RS19090	COG1846	Transcriptional regulator
KM843_RS19095	COG2153	protein acetylation
KM843_RS19105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KM843_RS19110	COG0583	DNA-binding transcription factor activity
KM843_RS19115	COG1028	Short-chain dehydrogenase reductase Sdr
KM843_RS19125	COG1331	Highly conserved protein containing a thioredoxin domain
KM843_RS19145	COG2815	serine threonine protein kinase
KM843_RS19145	COG0515	serine threonine protein kinase
KM843_RS19150	COG1331	Highly conserved protein containing a thioredoxin domain
KM843_RS19155	COG1266	CAAX protease self-immunity
KM843_RS19160	COG0477	Major facilitator Superfamily
KM843_RS19160	COG2814	Major facilitator Superfamily
KM843_RS19165	COG0346	lactoylglutathione lyase activity
KM843_RS19170	COG1609	Transcriptional regulator
KM843_RS19175	COG0708	Exodeoxyribonuclease III
KM843_RS19180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KM843_RS19185	COG2169	Transcriptional regulator
KM843_RS19195	COG0629	single-stranded DNA binding
KM843_RS19205	COG0012	GTP binding
KM843_RS19210	COG0243	molybdopterin cofactor binding
KM843_RS19215	COG4481	Protein conserved in bacteria
KM843_RS19220	COG3949	Membrane
KM843_RS19235	COG1475	DNA binding
KM843_RS19240	COG1192	Involved in chromosome partitioning
KM843_RS19265	COG1847	R3H domain protein
KM843_RS19270	COG0706	membrane insertase activity
KM843_RS19300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KM843_RS19375	COG0457	Tetratricopeptide repeat
KM843_RS19450	COG0513	Belongs to the DEAD box helicase family
KM843_RS19470	COG0305	Participates in initiation and elongation during chromosome replication
KM843_RS19580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM843_RS19580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KM843_RS19650	COG1191	sigma factor activity
KM843_RS19950	COG0210	DNA helicase
KM843_RS20040	COG0187	DNA topoisomerase II activity
KM843_RS20205	COG1705	Flagellar rod assembly protein muramidase FlgJ
KM843_RS20250	COG4474	Belongs to the UPF0398 family
KM843_RS20260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KM843_RS20330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KM843_RS20345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KM843_RS20355	COG4112	unkown
KM843_RS20445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KM843_RS20470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KM843_RS20480	COG0791	NLP P60 protein
KM843_RS20480	COG3883	PFAM NLP P60 protein
KM843_RS20540	COG1674	ftsk spoiiie
KM843_RS20600	COG3481	metal-dependent phosphohydrolase, HD sub domain
KM843_RS20630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KM843_RS20775	COG0457	Tetratricopeptide repeat