locus-tag	class	description
C9888_RS00010	COG0592	DNA-directed DNA polymerase activity
C9888_RS00015	COG2501	S4 domain
C9888_RS00030	COG0187	DNA topoisomerase II activity
C9888_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9888_RS00065	COG0516	GMP reductase activity
C9888_RS00065	COG0517	IMP dehydrogenase activity
C9888_RS00070	COG1686	Belongs to the peptidase S11 family
C9888_RS00090	COG1929	Belongs to the glycerate kinase type-1 family
C9888_RS00100	COG1428	Deoxynucleoside kinase
C9888_RS00105	COG1428	Deoxynucleoside kinase
C9888_RS00110	COG1388	LysM domain
C9888_RS00110	COG3858	chitin binding
C9888_RS00115	COG1335	isochorismatase
C9888_RS00120	COG0590	tRNA wobble adenosine to inosine editing
C9888_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C9888_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C9888_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C9888_RS00190	COG3853	Toxic anion resistance protein (TelA)
C9888_RS00195	COG1982	Orn Lys Arg decarboxylase major
C9888_RS00205	COG3870	Protein conserved in bacteria
C9888_RS00210	COG1728	Protein conserved in bacteria
C9888_RS00215	COG0470	DNA polymerase III
C9888_RS00220	COG1774	PSP1 C-terminal conserved region
C9888_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C9888_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9888_RS00245	COG2002	toxin-antitoxin pair type II binding
C9888_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9888_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9888_RS00255	COG0084	hydrolase, TatD family'
C9888_RS00260	COG3583	domain protein
C9888_RS00260	COG3584	3D domain protein
C9888_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C9888_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C9888_RS00280	COG4466	Protein conserved in bacteria
C9888_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C9888_RS00300	COG0251	oxidation-reduction process
C9888_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9888_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9888_RS00340	COG2002	toxin-antitoxin pair type II binding
C9888_RS00345	COG2244	polysaccharide biosynthetic process
C9888_RS00350	COG3956	TIGRFAM MazG family protein
C9888_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C9888_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C9888_RS00375	COG1098	S1 RNA binding domain
C9888_RS00390	COG2208	phosphoserine phosphatase activity
C9888_RS00395	COG2304	oxidoreductase activity
C9888_RS00400	COG0515	serine threonine protein kinase
C9888_RS00405	COG0037	tRNA processing
C9888_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C9888_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9888_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9888_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9888_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9888_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
C9888_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9888_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9888_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9888_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9888_RS00470	COG1396	sequence-specific DNA binding
C9888_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9888_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9888_RS00560	COG4463	regulation of RNA biosynthetic process
C9888_RS00565	COG3880	PFAM UvrB UvrC protein
C9888_RS00575	COG0542	response to heat
C9888_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C9888_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C9888_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
C9888_RS00610	COG1045	serine acetyltransferase
C9888_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C9888_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9888_RS00630	COG3688	RNA-binding protein containing a PIN domain
C9888_RS00635	COG1595	DNA-templated transcription, initiation
C9888_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9888_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
C9888_RS00675	COG2813	Specifically methylates the guanine in position
C9888_RS00690	COG1358	cellular component organization or biogenesis
C9888_RS00715	COG0596	Alpha beta hydrolase
C9888_RS00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C9888_RS00825	COG0201	protein transport
C9888_RS00835	COG0024	Methionine aminopeptidase
C9888_RS00850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C9888_RS00875	COG1122	ATPase activity
C9888_RS00880	COG1122	ATPase activity
C9888_RS00885	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C9888_RS00905	COG2226	methyltransferase
C9888_RS00910	COG2318	DinB family
C9888_RS00920	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9888_RS00925	COG0489	protein tyrosine kinase activity
C9888_RS00935	COG2194	sulfuric ester hydrolase activity
C9888_RS00940	COG0726	polysaccharide deacetylase
C9888_RS01000	COG0738	Major facilitator superfamily
C9888_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9888_RS01020	COG0659	secondary active sulfate transmembrane transporter activity
C9888_RS01025	COG0385	Bile acid
C9888_RS01030	COG2819	hydrolase of the alpha beta superfamily
C9888_RS01035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS01045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9888_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9888_RS01050	COG2207	Transcriptional regulator
C9888_RS01055	COG3876	Protein conserved in bacteria
C9888_RS01060	COG1472	Belongs to the glycosyl hydrolase 3 family
C9888_RS01065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9888_RS01070	COG1263	PTS System
C9888_RS01070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS01080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS01085	COG1683	Conserved Protein
C9888_RS01115	COG1595	DNA-templated transcription, initiation
C9888_RS01120	COG5662	AntiSigma factor
C9888_RS01125	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C9888_RS01130	COG4856	YbbR-like protein
C9888_RS01175	COG1346	cytolysis
C9888_RS01180	COG1380	Effector of murein hydrolase LrgA
C9888_RS01185	COG1846	Transcriptional regulator
C9888_RS01190	COG1113	amino acid transport
C9888_RS01195	COG1011	Hydrolase
C9888_RS01200	COG4585	Histidine kinase
C9888_RS01205	COG2197	response regulator
C9888_RS01210	COG1131	(ABC) transporter
C9888_RS01250	COG0531	amino acid
C9888_RS01255	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C9888_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
C9888_RS01275	COG2271	Major facilitator Superfamily
C9888_RS01290	COG2368	4-hydroxyphenylacetate
C9888_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS01315	COG0371	Dehydrogenase
C9888_RS01325	COG1183	phosphatidylcholine synthase activity
C9888_RS01330	COG0586	Pfam SNARE associated Golgi protein
C9888_RS01335	COG0688	phosphatidylethanolamine metabolic process
C9888_RS01350	COG1301	dicarboxylic acid transport
C9888_RS01355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9888_RS01360	COG0833	amino acid
C9888_RS01365	COG2040	homocysteine
C9888_RS01370	COG1115	amino acid carrier protein
C9888_RS01375	COG2066	Belongs to the glutaminase family
C9888_RS01380	COG4191	Histidine kinase
C9888_RS01385	COG0784	Response regulator, receiver
C9888_RS01390	COG3173	Aminoglycoside phosphotransferase
C9888_RS01410	COG3773	Cell wall hydrolase
C9888_RS01420	COG3540	Alkaline phosphatase
C9888_RS01425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9888_RS01430	COG0805	protein transport
C9888_RS01440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9888_RS01445	COG0477	Major facilitator Superfamily
C9888_RS01450	COG1309	transcriptional regulator
C9888_RS01455	COG0252	asparaginase activity
C9888_RS01460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C9888_RS01465	COG1405	negative regulation of cell septum assembly
C9888_RS01465	COG3012	SEC-C Motif Domain Protein
C9888_RS01470	COG0667	Aldo Keto reductase
C9888_RS01480	COG1595	DNA-templated transcription, initiation
C9888_RS01485	COG1595	DNA-templated transcription, initiation
C9888_RS01490	COG1876	peptidase activity
C9888_RS01495	COG0457	Tetratricopeptide repeat
C9888_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS01505	COG0366	Alpha amylase catalytic
C9888_RS01510	COG0803	Belongs to the bacterial solute-binding protein 9 family
C9888_RS01515	COG1121	(ABC) transporter
C9888_RS01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9888_RS01525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS01530	COG2310	stress, protein
C9888_RS01535	COG2310	stress, protein
C9888_RS01540	COG2310	stress, protein
C9888_RS01545	COG0861	Integral membrane protein TerC family
C9888_RS01555	COG3853	Toxic anion resistance protein (TelA)
C9888_RS01560	COG0477	Major facilitator Superfamily
C9888_RS01565	COG0517	IMP dehydrogenase activity
C9888_RS01565	COG4175	Glycine betaine
C9888_RS01570	COG4176	ABC-type proline glycine betaine transport system permease component
C9888_RS01575	COG2113	Glycine betaine
C9888_RS01580	COG1473	amidohydrolase
C9888_RS01585	COG1288	antiporter activity
C9888_RS01595	COG0366	Alpha amylase catalytic
C9888_RS01605	COG2814	Major facilitator Superfamily
C9888_RS01610	COG1846	Transcriptional regulator
C9888_RS01615	COG1280	lysine exporter protein (LysE YggA)
C9888_RS01620	COG3403	YqcI/YcgG family
C9888_RS01625	COG1113	amino acid transport
C9888_RS01630	COG3665	Urea carboxylase-associated protein
C9888_RS01645	COG1660	Displays ATPase and GTPase activities
C9888_RS01655	COG2271	Major facilitator Superfamily
C9888_RS01660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C9888_RS01665	COG3458	cephalosporin-C deacetylase activity
C9888_RS01670	COG3541	Predicted nucleotidyltransferase
C9888_RS01675	COG0506	proline dehydrogenase activity
C9888_RS01680	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS01685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9888_RS01690	COG2508	Transcriptional regulator
C9888_RS01700	COG1587	Uroporphyrinogen-III synthase
C9888_RS01700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9888_RS01705	COG2146	nitrite reductase [NAD(P)H] activity
C9888_RS01710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9888_RS01715	COG0243	molybdopterin cofactor binding
C9888_RS01720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9888_RS01725	COG2223	nitrite transmembrane transporter activity
C9888_RS01730	COG0523	cobalamin synthesis protein
C9888_RS01735	COG1063	alcohol dehydrogenase
C9888_RS01740	COG1714	RDD family
C9888_RS01750	COG2723	6-phospho-beta-galactosidase activity
C9888_RS01760	COG3209	COG3209 Rhs family protein
C9888_RS01765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9888_RS01770	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
C9888_RS01775	COG1733	regulation of RNA biosynthetic process
C9888_RS01785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS01790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS01795	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C9888_RS01810	COG2364	Membrane
C9888_RS01815	COG1126	abc transporter atp-binding protein
C9888_RS01820	COG0765	amino acid transport
C9888_RS01825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS01830	COG0583	DNA-binding transcription factor activity
C9888_RS01835	COG0163	prenyltransferase activity
C9888_RS01840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9888_RS01855	COG3104	oligopeptide transport
C9888_RS01860	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS01870	COG0697	spore germination
C9888_RS01880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9888_RS01885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS01890	COG0456	acetyltransferase
C9888_RS01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS01900	COG0765	amino acid transport
C9888_RS01905	COG1126	abc transporter atp-binding protein
C9888_RS01910	COG1473	amidohydrolase
C9888_RS01915	COG2079	MmgE PrpD family protein
C9888_RS01920	COG1136	(ABC) transporter
C9888_RS01925	COG0577	efflux transmembrane transporter activity
C9888_RS01930	COG0745	RESPONSE REGULATOR receiver
C9888_RS01935	COG3850	Histidine kinase
C9888_RS01935	COG5002	protein histidine kinase activity
C9888_RS01940	COG0457	Tetratricopeptide repeat
C9888_RS01955	COG0527	aspartate kinase activity
C9888_RS01960	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS01965	COG4605	iron ion homeostasis
C9888_RS01970	COG4604	ABC transporter, ATP-binding protein
C9888_RS01975	COG4607	ABC-type enterochelin transport system periplasmic component
C9888_RS01980	COG2814	Major facilitator Superfamily
C9888_RS01985	COG1309	transcriptional regulator
C9888_RS01990	COG0778	Nitroreductase
C9888_RS01995	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9888_RS02000	COG0640	Transcriptional regulator
C9888_RS02005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS02010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9888_RS02015	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS02020	COG4975	Glucose uptake
C9888_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS02030	COG4549	nuclear export factor GLE1
C9888_RS02035	COG1276	copper resistance
C9888_RS02035	COG2372	response to copper ion
C9888_RS02040	COG1349	DNA-binding transcription factor activity
C9888_RS02050	COG2213	PTS system mannitol-specific
C9888_RS02055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS02065	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9888_RS02075	COG0561	phosphatase activity
C9888_RS02085	COG1914	H( )-stimulated, divalent metal cation uptake system
C9888_RS02095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9888_RS02100	COG1984	allophanate hydrolase subunit 2
C9888_RS02105	COG1414	Transcriptional regulator
C9888_RS02110	COG2755	lipolytic protein G-D-S-L family
C9888_RS02120	COG2329	Antibiotic biosynthesis monooxygenase
C9888_RS02125	COG0768	penicillin binding
C9888_RS02130	COG4989	oxidoreductase activity
C9888_RS02135	COG3711	transcriptional antiterminator
C9888_RS02140	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS02150	COG1917	Cupin 2, conserved barrel domain protein
C9888_RS02155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS02160	COG3871	stress protein (general stress protein 26)
C9888_RS02170	COG2814	Major facilitator Superfamily
C9888_RS02175	COG1522	sequence-specific DNA binding
C9888_RS02180	COG0551	DNA topoisomerase type I activity
C9888_RS02180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9888_RS02185	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C9888_RS02190	COG3706	GGDEF domain
C9888_RS02195	COG5298	Protein conserved in bacteria
C9888_RS02200	COG1215	transferase activity, transferring glycosyl groups
C9888_RS02210	COG0531	amino acid
C9888_RS02215	COG0494	nUDIX hydrolase
C9888_RS02220	COG0028	Belongs to the TPP enzyme family
C9888_RS02255	COG1914	H( )-stimulated, divalent metal cation uptake system
C9888_RS02270	COG4876	unkown
C9888_RS02280	COG2076	Multidrug Resistance protein
C9888_RS02285	COG2217	Heavy metal translocating P-type atpase
C9888_RS02290	COG3729	General stress protein
C9888_RS02295	COG0662	Cupin 2, conserved barrel domain protein
C9888_RS02300	COG2329	Antibiotic biosynthesis monooxygenase
C9888_RS02305	COG3546	catalase activity
C9888_RS02310	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C9888_RS02315	COG3290	protein histidine kinase activity
C9888_RS02320	COG4565	transcriptional regulatory protein
C9888_RS02325	COG1301	dicarboxylic acid transport
C9888_RS02330	COG0628	permease
C9888_RS02335	COG1131	(ABC) transporter
C9888_RS02340	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C9888_RS02350	COG1960	acyl-CoA dehydrogenase activity
C9888_RS02365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C9888_RS02370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS02380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9888_RS02385	COG0513	Belongs to the DEAD box helicase family
C9888_RS02390	COG3402	PFAM membrane-flanked domain
C9888_RS02395	COG3428	Bacterial PH domain
C9888_RS02400	COG0705	Rhomboid family
C9888_RS02410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C9888_RS02415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9888_RS02420	COG0864	Transcriptional regulator
C9888_RS02425	COG2337	Toxic component of a toxin-antitoxin (TA) module
C9888_RS02430	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS02435	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS02440	COG2172	sigma factor antagonist activity
C9888_RS02445	COG2208	phosphoserine phosphatase activity
C9888_RS02450	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS02460	COG1191	sigma factor activity
C9888_RS02465	COG2208	phosphoserine phosphatase activity
C9888_RS02470	COG2183	response to ionizing radiation
C9888_RS02520	COG0457	Tetratricopeptide repeat
C9888_RS02530	COG0477	Major facilitator Superfamily
C9888_RS02550	COG2030	dehydratase
C9888_RS02565	COG1959	2 iron, 2 sulfur cluster binding
C9888_RS02570	COG2910	NAD(P)H-binding
C9888_RS02580	COG1309	transcriptional regulator
C9888_RS02585	COG3239	Fatty acid desaturase
C9888_RS02595	COG1278	Cold shock
C9888_RS02600	COG1329	Transcriptional regulator
C9888_RS02605	COG1937	Protein conserved in bacteria
C9888_RS02610	COG2210	Belongs to the sulfur carrier protein TusA family
C9888_RS02615	COG1054	Belongs to the UPF0176 family
C9888_RS02620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9888_RS02620	COG0425	Belongs to the sulfur carrier protein TusA family
C9888_RS02625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9888_RS02625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS02630	COG0425	Belongs to the sulfur carrier protein TusA family
C9888_RS02635	COG0730	response to heat
C9888_RS02640	COG1794	racemase activity, acting on amino acids and derivatives
C9888_RS02655	COG3621	Patatin-like phospholipase
C9888_RS02665	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9888_RS02670	COG1802	Transcriptional regulator
C9888_RS02675	COG0251	oxidation-reduction process
C9888_RS02680	COG0814	amino acid
C9888_RS02685	COG1473	amidohydrolase
C9888_RS02690	COG1917	Cupin 2, conserved barrel domain protein
C9888_RS02690	COG2207	Transcriptional regulator
C9888_RS02700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS02705	COG0477	Major facilitator Superfamily
C9888_RS02725	COG0277	FAD linked oxidase domain protein
C9888_RS02755	COG2318	DinB family
C9888_RS02785	COG0351	phosphomethylpyrimidine kinase
C9888_RS02800	COG1064	alcohol dehydrogenase
C9888_RS02805	COG0789	Transcriptional regulator
C9888_RS02815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS02830	COG2814	Major facilitator Superfamily
C9888_RS02835	COG1309	transcriptional regulator
C9888_RS02840	COG0697	spore germination
C9888_RS02845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS02850	COG5577	PFAM Coat F domain
C9888_RS02860	COG1063	alcohol dehydrogenase
C9888_RS02865	COG5577	PFAM Coat F domain
C9888_RS02875	COG0738	Major facilitator superfamily
C9888_RS02900	COG4585	Histidine kinase
C9888_RS02905	COG2197	response regulator
C9888_RS02910	COG2409	Drug exporters of the RND superfamily
C9888_RS02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9888_RS02920	COG0488	(ABC) transporter
C9888_RS02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS02940	COG2814	Major facilitator Superfamily
C9888_RS02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9888_RS02955	COG0730	response to heat
C9888_RS02960	COG0456	acetyltransferase
C9888_RS02965	COG4978	Transcriptional regulator
C9888_RS02965	COG0789	Transcriptional regulator
C9888_RS02970	COG0697	spore germination
C9888_RS02975	COG1051	belongs to the nudix hydrolase family
C9888_RS02980	COG2226	methyltransferase
C9888_RS02985	COG0473	3-isopropylmalate dehydrogenase activity
C9888_RS02990	COG1802	Transcriptional regulator
C9888_RS02995	COG1819	glycosyl
C9888_RS03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9888_RS03015	COG1388	LysM domain
C9888_RS03020	COG2814	Major facilitator Superfamily
C9888_RS03025	COG2188	Transcriptional regulator
C9888_RS03030	COG2186	Transcriptional regulator
C9888_RS03035	COG2807	transmembrane transport
C9888_RS03040	COG2076	Multidrug Resistance protein
C9888_RS03045	COG2076	Multidrug Resistance protein
C9888_RS03050	COG1309	transcriptional regulator
C9888_RS03055	COG0531	amino acid
C9888_RS03065	COG3832	glyoxalase III activity
C9888_RS03070	COG0604	alcohol dehydrogenase
C9888_RS03075	COG2814	Major facilitator Superfamily
C9888_RS03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C9888_RS03120	COG0802	atpase or kinase
C9888_RS03125	COG1214	PFAM Peptidase M22, glycoprotease
C9888_RS03130	COG0456	acetyltransferase
C9888_RS03135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9888_RS03140	COG0488	(ABC) transporter
C9888_RS03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9888_RS03160	COG0805	protein transport
C9888_RS03170	COG1266	CAAX protease self-immunity
C9888_RS03195	COG0457	Tetratricopeptide repeat
C9888_RS03200	COG1063	alcohol dehydrogenase
C9888_RS03205	COG2211	Major facilitator Superfamily
C9888_RS03210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9888_RS03220	COG1842	Phage shock protein A
C9888_RS03225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9888_RS03230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C9888_RS03235	COG4260	virion core protein, lumpy skin disease virus
C9888_RS03240	COG2755	lipolytic protein G-D-S-L family
C9888_RS03240	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C9888_RS03250	COG1595	DNA-templated transcription, initiation
C9888_RS03255	COG1063	alcohol dehydrogenase
C9888_RS03260	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9888_RS03265	COG0823	Involved in the tonB-independent uptake of proteins
C9888_RS03275	COG2132	Multicopper oxidase
C9888_RS03280	COG1113	amino acid transport
C9888_RS03285	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C9888_RS03290	COG0714	Associated with various cellular activities
C9888_RS03295	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C9888_RS03300	COG1305	Transglutaminase-like
C9888_RS03310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9888_RS03330	COG2211	Major facilitator Superfamily
C9888_RS03345	COG2252	PERMEase
C9888_RS03350	COG3064	Membrane
C9888_RS03370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9888_RS03375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9888_RS03380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9888_RS03385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C9888_RS03390	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9888_RS03405	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C9888_RS03415	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9888_RS03420	COG0138	bifunctional purine biosynthesis protein purh
C9888_RS03425	COG0151	Belongs to the GarS family
C9888_RS03435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C9888_RS03440	COG1470	cell adhesion involved in biofilm formation
C9888_RS03445	COG4496	protein, YerC YecD
C9888_RS03465	COG0210	DNA helicase
C9888_RS03475	COG4851	CamS sex pheromone cAM373 precursor
C9888_RS03480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9888_RS03485	COG1285	pathogenesis
C9888_RS03490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9888_RS03510	COG1309	transcriptional regulator
C9888_RS03515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9888_RS03520	COG1597	lipid kinase activity
C9888_RS03525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9888_RS03530	COG1136	(ABC) transporter
C9888_RS03540	COG1131	(ABC) transporter
C9888_RS03615	COG3546	catalase activity
C9888_RS03620	COG0454	-acetyltransferase
C9888_RS03630	COG2323	membrane
C9888_RS03635	COG2329	Antibiotic biosynthesis monooxygenase
C9888_RS03645	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS03650	COG5583	Uncharacterized small protein (DUF2292)
C9888_RS03655	COG0196	riboflavin kinase activity
C9888_RS03660	COG0670	Belongs to the BI1 family
C9888_RS03665	COG1846	Transcriptional regulator
C9888_RS03670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9888_RS03680	COG2124	cytochrome p450
C9888_RS03680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9888_RS03695	COG1131	(ABC) transporter
C9888_RS03710	COG1368	sulfuric ester hydrolase activity
C9888_RS03715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C9888_RS03720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS03725	COG1442	glycosyl transferase family 8
C9888_RS03730	COG1216	Glycosyl transferase, family 2
C9888_RS03735	COG1442	glycosyl transferase family 8
C9888_RS03740	COG2223	nitrite transmembrane transporter activity
C9888_RS03745	COG0531	amino acid
C9888_RS03750	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS03755	COG0840	transmembrane signaling receptor activity
C9888_RS03760	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS03765	COG0463	Glycosyl transferase, family 2
C9888_RS03765	COG0457	Tetratricopeptide repeat
C9888_RS03770	COG0488	(ABC) transporter
C9888_RS03775	COG0789	Transcriptional regulator
C9888_RS03780	COG2814	Major facilitator Superfamily
C9888_RS03785	COG0488	(ABC) transporter
C9888_RS03790	COG0513	Belongs to the DEAD box helicase family
C9888_RS03800	COG2130	NADP-dependent
C9888_RS03815	COG3866	Pectate lyase
C9888_RS03820	COG0471	metal ion transport
C9888_RS03835	COG2972	Histidine kinase
C9888_RS03835	COG0745	RESPONSE REGULATOR receiver
C9888_RS03840	COG3279	Response regulator of the LytR AlgR family
C9888_RS03850	COG3764	Sortase (surface protein transpeptidase)
C9888_RS03855	COG3290	protein histidine kinase activity
C9888_RS03860	COG4565	transcriptional regulatory protein
C9888_RS03865	COG3181	Tripartite tricarboxylate transporter family receptor
C9888_RS03870	COG2851	Citrate transporter
C9888_RS03875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS03880	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C9888_RS03890	COG2258	MOSC domain
C9888_RS03910	COG0024	Methionine aminopeptidase
C9888_RS03915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS03915	COG1263	PTS System
C9888_RS03925	COG1368	sulfuric ester hydrolase activity
C9888_RS03935	COG0071	Belongs to the small heat shock protein (HSP20) family
C9888_RS03950	COG1263	PTS System
C9888_RS03950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS03955	COG0366	Alpha amylase catalytic
C9888_RS03960	COG2188	Transcriptional regulator
C9888_RS03965	COG0778	Nitroreductase
C9888_RS03980	COG0737	Belongs to the 5'-nucleotidase family
C9888_RS03985	COG0693	protein deglycase activity
C9888_RS03990	COG1609	Transcriptional regulator
C9888_RS04005	COG2814	Major facilitator Superfamily
C9888_RS04015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9888_RS04020	COG4980	gas vesicle protein
C9888_RS04025	COG1295	ribonuclease BN
C9888_RS04030	COG0477	Major facilitator Superfamily
C9888_RS04035	COG0387	Pfam Sodium calcium exchanger
C9888_RS04045	COG0668	transmembrane transport
C9888_RS04050	COG0535	radical SAM domain protein
C9888_RS04060	COG0726	polysaccharide deacetylase
C9888_RS04080	COG0745	RESPONSE REGULATOR receiver
C9888_RS04085	COG2205	protein histidine kinase activity
C9888_RS04090	COG2084	Dehydrogenase
C9888_RS04100	COG0598	Magnesium transport protein CorA
C9888_RS04105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9888_RS04110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9888_RS04125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9888_RS04130	COG4637	Psort location Cytoplasmic, score
C9888_RS04135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C9888_RS04140	COG0022	dehydrogenase e1 component
C9888_RS04145	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9888_RS04150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9888_RS04155	COG3284	Transcriptional regulator
C9888_RS04165	COG1486	melibiose metabolic process
C9888_RS04170	COG1737	Transcriptional regulator
C9888_RS04175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS04175	COG1263	PTS System
C9888_RS04180	COG1132	(ABC) transporter
C9888_RS04185	COG1132	(ABC) transporter
C9888_RS04190	COG2259	Doxx family
C9888_RS04195	COG2514	catechol 2,3-dioxygenase activity
C9888_RS04210	COG1695	Transcriptional regulator
C9888_RS04215	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9888_RS04220	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C9888_RS04230	COG3848	Pyruvate phosphate dikinase
C9888_RS04230	COG0574	Belongs to the PEP-utilizing enzyme family
C9888_RS04235	COG2732	(Barnase) inhibitor
C9888_RS04240	COG2318	DinB family
C9888_RS04245	COG2814	Major facilitator Superfamily
C9888_RS04250	COG1846	Transcriptional regulator
C9888_RS04255	COG0392	lysyltransferase activity
C9888_RS04255	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C9888_RS04260	COG0384	phenazine biosynthesis protein PhzF
C9888_RS04265	COG0778	Nitroreductase
C9888_RS04280	COG1090	epimerase
C9888_RS04295	COG2814	Major facilitator Superfamily
C9888_RS04305	COG3591	Belongs to the peptidase S1B family
C9888_RS04320	COG3103	Sh3 type 3 domain protein
C9888_RS04325	COG5658	integral membrane protein
C9888_RS04330	COG0596	Alpha beta hydrolase
C9888_RS04335	COG0463	Glycosyl transferase, family 2
C9888_RS04340	COG4485	Bacterial membrane protein, YfhO
C9888_RS04345	COG1988	membrane-bound metal-dependent
C9888_RS04350	COG1194	a g-specific adenine glycosylase
C9888_RS04360	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS04380	COG1132	(ABC) transporter
C9888_RS04385	COG4129	membrane
C9888_RS04395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9888_RS04400	COG0735	belongs to the Fur family
C9888_RS04510	COG1757	Na H antiporter
C9888_RS04515	COG3340	Belongs to the peptidase S51 family
C9888_RS04525	COG0277	FAD linked oxidase domain protein
C9888_RS04535	COG0747	negative chemotaxis
C9888_RS04540	COG0601	transmembrane transport
C9888_RS04545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9888_RS04550	COG0444	Belongs to the ABC transporter superfamily
C9888_RS04555	COG4608	Belongs to the ABC transporter superfamily
C9888_RS04570	COG1116	anion transmembrane transporter activity
C9888_RS04575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9888_RS04580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9888_RS04600	COG1476	TRANSCRIPTIONal
C9888_RS04610	COG3382	B3 4 domain protein
C9888_RS04615	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C9888_RS04625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C9888_RS04630	COG0789	Transcriptional regulator
C9888_RS04635	COG1664	Polymer-forming cytoskeletal
C9888_RS04640	COG1664	Polymer-forming cytoskeletal
C9888_RS04650	COG2766	serine protein kinase
C9888_RS04665	COG1846	Transcriptional regulator
C9888_RS04670	COG1566	PFAM secretion protein HlyD family protein
C9888_RS04675	COG2814	Major facilitator Superfamily
C9888_RS04680	COG0655	NAD(P)H dehydrogenase (quinone) activity
C9888_RS04695	COG1725	Transcriptional regulator
C9888_RS04700	COG1131	(ABC) transporter
C9888_RS04705	COG1131	(ABC) transporter
C9888_RS04710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C9888_RS04715	COG1278	Cold shock
C9888_RS04725	COG1464	Belongs to the NlpA lipoprotein family
C9888_RS04730	COG3706	GGDEF domain
C9888_RS04735	COG1823	symporter activity
C9888_RS04755	COG5577	PFAM Coat F domain
C9888_RS04760	COG4085	toxin activity
C9888_RS04760	COG0737	Belongs to the 5'-nucleotidase family
C9888_RS04760	COG1525	nuclease
C9888_RS04765	COG3764	Sortase (surface protein transpeptidase)
C9888_RS04770	COG0564	pseudouridine synthase activity
C9888_RS04780	COG0517	IMP dehydrogenase activity
C9888_RS04785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9888_RS04790	COG3153	acetyltransferase
C9888_RS04790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9888_RS04795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9888_RS04800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C9888_RS04805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9888_RS04815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9888_RS04820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9888_RS04825	COG2203	Gaf domain
C9888_RS04825	COG4585	Histidine kinase
C9888_RS04830	COG2197	response regulator
C9888_RS04835	COG0431	NADPH-dependent FMN reductase
C9888_RS04850	COG1388	LysM domain
C9888_RS04850	COG0791	NLP P60 protein
C9888_RS04855	COG1959	2 iron, 2 sulfur cluster binding
C9888_RS04860	COG0668	transmembrane transport
C9888_RS04865	COG2719	SpoVR family
C9888_RS04870	COG1785	Belongs to the alkaline phosphatase family
C9888_RS04875	COG1388	LysM domain
C9888_RS04875	COG0791	NLP P60 protein
C9888_RS04880	COG0583	DNA-binding transcription factor activity
C9888_RS04885	COG0372	Belongs to the citrate synthase family
C9888_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS04895	COG0531	amino acid
C9888_RS04900	COG0733	neurotransmitter:sodium symporter activity
C9888_RS04915	COG1595	DNA-templated transcription, initiation
C9888_RS04920	COG0204	Acyl-transferase
C9888_RS04925	COG1253	flavin adenine dinucleotide binding
C9888_RS04930	COG0789	Transcriptional regulator
C9888_RS04935	COG0436	Aminotransferase
C9888_RS04940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9888_RS04945	COG1253	flavin adenine dinucleotide binding
C9888_RS04950	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9888_RS04955	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9888_RS04960	COG0584	glycerophosphoryl diester phosphodiesterase
C9888_RS04970	COG0668	transmembrane transport
C9888_RS04975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9888_RS04980	COG0726	polysaccharide deacetylase
C9888_RS04985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9888_RS04990	COG3226	Transcriptional regulator
C9888_RS05000	COG0589	response to stress
C9888_RS05005	COG1132	(ABC) transporter
C9888_RS05010	COG1132	(ABC) transporter
C9888_RS05015	COG0702	epimerase
C9888_RS05035	COG0189	ligase activity
C9888_RS05040	COG0189	ligase activity
C9888_RS05055	COG4335	DNA alkylation repair
C9888_RS05060	COG0561	phosphatase activity
C9888_RS05065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9888_RS05075	COG0475	glutathione-regulated potassium exporter activity
C9888_RS05080	COG0490	domain, Protein
C9888_RS05090	COG1024	Enoyl-CoA hydratase
C9888_RS05100	COG4152	abc transporter atp-binding protein
C9888_RS05105	COG1668	transmembrane transport
C9888_RS05110	COG0420	3'-5' exonuclease activity
C9888_RS05115	COG4717	serine-type aminopeptidase activity
C9888_RS05130	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9888_RS05170	COG4980	gas vesicle protein
C9888_RS05185	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C9888_RS05190	COG0537	adenosine 5'-monophosphoramidase activity
C9888_RS05195	COG1131	(ABC) transporter
C9888_RS05200	COG4473	ABC transporter
C9888_RS05210	COG1473	amidohydrolase
C9888_RS05215	COG3069	C4-dicarboxylate transmembrane transporter activity
C9888_RS05220	COG2329	Antibiotic biosynthesis monooxygenase
C9888_RS05225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9888_RS05235	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9888_RS05240	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C9888_RS05245	COG1309	transcriptional regulator
C9888_RS05250	COG1511	domain protein
C9888_RS05255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9888_RS05265	COG1363	Peptidase, m42
C9888_RS05270	COG1301	dicarboxylic acid transport
C9888_RS05280	COG1234	tRNA 3'-trailer cleavage
C9888_RS05285	COG0095	Lipoate-protein ligase
C9888_RS05290	COG0702	epimerase
C9888_RS05295	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS05305	COG0501	Belongs to the peptidase M48B family
C9888_RS05310	COG1404	Belongs to the peptidase S8 family
C9888_RS05320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9888_RS05325	COG0406	alpha-ribazole phosphatase activity
C9888_RS05330	COG0183	Belongs to the thiolase family
C9888_RS05335	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS05340	COG1268	BioY protein
C9888_RS05345	COG0840	transmembrane signaling receptor activity
C9888_RS05350	COG0723	plastoquinol--plastocyanin reductase activity
C9888_RS05350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9888_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS05365	COG4903	ComK protein
C9888_RS05370	COG5646	InterPro IPR014922
C9888_RS05395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9888_RS05410	COG0398	Pfam SNARE associated Golgi protein
C9888_RS05415	COG0681	Belongs to the peptidase S26 family
C9888_RS05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9888_RS05425	COG1846	Transcriptional regulator
C9888_RS05430	COG3180	Ammonia monooxygenase
C9888_RS05435	COG2814	Major facilitator Superfamily
C9888_RS05445	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C9888_RS05450	COG2323	membrane
C9888_RS05465	COG0420	3'-5' exonuclease activity
C9888_RS05470	COG0419	ATPase involved in DNA repair
C9888_RS05475	COG1403	HNH endonuclease
C9888_RS05515	COG0179	Fumarylacetoacetate (FAA) hydrolase
C9888_RS05530	COG0367	asparagine synthase
C9888_RS05535	COG1562	ergosterol biosynthetic process
C9888_RS05540	COG0534	Mate efflux family protein
C9888_RS05545	COG1917	Cupin 2, conserved barrel domain protein
C9888_RS05545	COG2207	Transcriptional regulator
C9888_RS05550	COG1609	Transcriptional regulator
C9888_RS05555	COG0673	inositol 2-dehydrogenase activity
C9888_RS05560	COG2318	DinB family
C9888_RS05565	COG1279	arginine transmembrane transporter activity
C9888_RS05570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS05575	COG1357	PFAM Pentapeptide repeats (8 copies)
C9888_RS05580	COG2153	protein acetylation
C9888_RS05585	COG0646	methionine synthase
C9888_RS05585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C9888_RS05595	COG2996	Protein conserved in bacteria
C9888_RS05600	COG1744	ABC transporter substrate-binding protein PnrA-like
C9888_RS05605	COG0840	transmembrane signaling receptor activity
C9888_RS05610	COG2124	cytochrome p450
C9888_RS05620	COG1307	EDD domain protein, DegV family
C9888_RS05625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS05640	COG0561	phosphatase activity
C9888_RS05645	COG1073	alpha beta
C9888_RS05650	COG2151	metal-sulfur cluster biosynthetic enzyme
C9888_RS05660	COG0277	FAD linked oxidase domain protein
C9888_RS05665	COG2271	Major facilitator Superfamily
C9888_RS05675	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C9888_RS05685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9888_RS05690	COG0505	Belongs to the CarA family
C9888_RS05695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9888_RS05700	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9888_RS05720	COG2267	carboxylic ester hydrolase activity
C9888_RS05730	COG1744	ABC transporter substrate-binding protein PnrA-like
C9888_RS05745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9888_RS05750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9888_RS05755	COG5504	Zn-dependent protease
C9888_RS05760	COG0444	Belongs to the ABC transporter superfamily
C9888_RS05765	COG4608	Belongs to the ABC transporter superfamily
C9888_RS05775	COG0601	transmembrane transport
C9888_RS05780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9888_RS05790	COG0180	Tryptophanyl-tRNA synthetase
C9888_RS05795	COG4166	transmembrane transport
C9888_RS05800	COG0601	transmembrane transport
C9888_RS05805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9888_RS05810	COG0444	Belongs to the ABC transporter superfamily
C9888_RS05815	COG4608	Belongs to the ABC transporter superfamily
C9888_RS05825	COG0456	acetyltransferase
C9888_RS05830	COG1393	Belongs to the ArsC family
C9888_RS05835	COG0861	Integral membrane protein TerC family
C9888_RS05840	COG4862	establishment of competence for transformation
C9888_RS05845	COG4469	Competence protein
C9888_RS05850	COG1164	Oligoendopeptidase f
C9888_RS05855	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C9888_RS05860	COG2346	COG2346, Truncated hemoglobins
C9888_RS05865	COG0741	lytic transglycosylase activity
C9888_RS05870	COG4116	CYTH
C9888_RS05880	COG2357	RelA SpoT domain protein
C9888_RS05885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C9888_RS05890	COG0564	pseudouridine synthase activity
C9888_RS05905	COG0475	glutathione-regulated potassium exporter activity
C9888_RS05905	COG0569	domain protein
C9888_RS05910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C9888_RS05920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9888_RS05925	COG2104	thiamine diphosphate biosynthetic process
C9888_RS05935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9888_RS05940	COG0351	phosphomethylpyrimidine kinase
C9888_RS05945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9888_RS06000	COG0210	DNA helicase
C9888_RS06020	COG1131	(ABC) transporter
C9888_RS06030	COG2153	protein acetylation
C9888_RS06040	COG2382	esterase
C9888_RS06045	COG0626	cystathionine gamma-synthase activity
C9888_RS06050	COG0626	cystathionine gamma-synthase activity
C9888_RS06060	COG0582	viral genome integration into host DNA
C9888_RS06145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9888_RS06180	COG0741	lytic transglycosylase activity
C9888_RS06180	COG1196	nuclear chromosome segregation
C9888_RS06180	COG0739	heme binding
C9888_RS06260	COG5444	nuclease activity
C9888_RS06280	COG0135	phosphoribosylanthranilate isomerase activity
C9888_RS06290	COG0346	lactoylglutathione lyase activity
C9888_RS06295	COG2367	Beta-lactamase
C9888_RS06300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9888_RS06305	COG0477	Major facilitator Superfamily
C9888_RS06310	COG1846	Transcriptional regulator
C9888_RS06320	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C9888_RS06325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9888_RS06330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9888_RS06335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS06335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS06340	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9888_RS06370	COG1285	pathogenesis
C9888_RS06385	COG2205	protein histidine kinase activity
C9888_RS06395	COG3383	formate dehydrogenase (NAD+) activity
C9888_RS06400	COG2427	Protein of unknown function (DUF1641)
C9888_RS06405	COG2124	cytochrome p450
C9888_RS06410	COG1819	glycosyl
C9888_RS06420	COG1587	Uroporphyrinogen-III synthase
C9888_RS06425	COG0390	transport system, permease component
C9888_RS06430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9888_RS06435	COG0697	spore germination
C9888_RS06440	COG4297	protein containing double-stranded beta helix domain
C9888_RS06450	COG1252	NADH dehydrogenase
C9888_RS06460	COG2211	Major facilitator Superfamily
C9888_RS06465	COG1609	Transcriptional regulator
C9888_RS06470	COG0246	Mannitol dehydrogenase
C9888_RS06475	COG2721	sulfolactate sulfo-lyase activity
C9888_RS06480	COG0730	response to heat
C9888_RS06485	COG2318	DinB family
C9888_RS06490	COG0457	Tetratricopeptide repeat
C9888_RS06495	COG5632	N-Acetylmuramoyl-L-alanine amidase
C9888_RS06495	COG1388	LysM domain
C9888_RS06495	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS06505	COG4195	phage-related replication protein
C9888_RS06510	COG2856	Zn peptidase
C9888_RS06515	COG1396	sequence-specific DNA binding
C9888_RS06525	COG1522	sequence-specific DNA binding
C9888_RS06530	COG1484	DNA-dependent DNA replication
C9888_RS06545	COG1595	DNA-templated transcription, initiation
C9888_RS06550	COG4193	domain, Protein
C9888_RS06585	COG5632	N-Acetylmuramoyl-L-alanine amidase
C9888_RS06585	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS06600	COG0306	phosphate transporter
C9888_RS06605	COG1392	Phosphate transport regulator
C9888_RS06610	COG0531	amino acid
C9888_RS06615	COG0346	lactoylglutathione lyase activity
C9888_RS06620	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C9888_RS06625	COG0463	Glycosyl transferase, family 2
C9888_RS06630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9888_RS06635	COG0477	Major facilitator Superfamily
C9888_RS06640	COG2362	D-Aminopeptidase
C9888_RS06645	COG0601	transmembrane transport
C9888_RS06650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9888_RS06655	COG0444	Belongs to the ABC transporter superfamily
C9888_RS06660	COG4166	transmembrane transport
C9888_RS06665	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9888_RS06670	COG4948	Mandelate Racemase Muconate Lactonizing
C9888_RS06675	COG0791	NLP P60 protein
C9888_RS06680	COG4608	Belongs to the ABC transporter superfamily
C9888_RS06685	COG2706	6-phosphogluconolactonase activity
C9888_RS06690	COG1834	amidinotransferase
C9888_RS06695	COG1607	acyl-coa hydrolase
C9888_RS06700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS06705	COG2076	Multidrug Resistance protein
C9888_RS06710	COG2076	Multidrug Resistance protein
C9888_RS06715	COG0788	formyltetrahydrofolate deformylase activity
C9888_RS06720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9888_RS06730	COG1764	response to oxidative stress
C9888_RS06735	COG1846	Transcriptional regulator
C9888_RS06740	COG1764	response to oxidative stress
C9888_RS06755	COG0463	Glycosyl transferase, family 2
C9888_RS06755	COG0457	Tetratricopeptide repeat
C9888_RS06765	COG2814	Major facilitator Superfamily
C9888_RS06770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9888_RS06780	COG1404	Belongs to the peptidase S8 family
C9888_RS06785	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS06790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C9888_RS06795	COG1122	ATPase activity
C9888_RS06800	COG4721	ABC-type cobalt transport system, permease component
C9888_RS06805	COG3858	chitin binding
C9888_RS06805	COG1388	LysM domain
C9888_RS06825	COG2239	Acts as a magnesium transporter
C9888_RS06830	COG0789	Transcriptional regulator
C9888_RS06845	COG1846	Transcriptional regulator
C9888_RS06850	COG0726	polysaccharide deacetylase
C9888_RS06855	COG1793	dna ligase
C9888_RS06855	COG3285	dna ligase
C9888_RS06860	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C9888_RS06870	COG0586	Pfam SNARE associated Golgi protein
C9888_RS06875	COG0861	Integral membrane protein TerC family
C9888_RS06880	COG1191	sigma factor activity
C9888_RS06905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9888_RS06910	COG2323	membrane
C9888_RS06920	COG3594	Acyltransferase
C9888_RS06925	COG5002	protein histidine kinase activity
C9888_RS06930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9888_RS06945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9888_RS06950	COG0436	Aminotransferase
C9888_RS06980	COG3852	Histidine kinase
C9888_RS06985	COG1846	Transcriptional regulator
C9888_RS06990	COG1360	Flagellar Motor Protein
C9888_RS06995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9888_RS07000	COG0542	response to heat
C9888_RS07010	COG3949	Membrane
C9888_RS07025	COG0720	synthase
C9888_RS07030	COG0602	queuosine metabolic process
C9888_RS07040	COG1733	regulation of RNA biosynthetic process
C9888_RS07045	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS07060	COG4873	Protein conserved in bacteria
C9888_RS07070	COG3773	Cell wall hydrolase
C9888_RS07075	COG2244	polysaccharide biosynthetic process
C9888_RS07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS07085	COG2217	Heavy metal translocating P-type atpase
C9888_RS07090	COG0006	proline dipeptidase activity
C9888_RS07095	COG1609	Transcriptional regulator
C9888_RS07100	COG3711	transcriptional antiterminator
C9888_RS07105	COG2190	(PTS) system
C9888_RS07105	COG1263	PTS System
C9888_RS07105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS07110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS07115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9888_RS07125	COG1533	DNA photolyase activity
C9888_RS07130	COG0840	transmembrane signaling receptor activity
C9888_RS07135	COG2084	Dehydrogenase
C9888_RS07145	COG2340	Cysteine-rich secretory protein family
C9888_RS07150	COG0768	penicillin binding
C9888_RS07155	COG4191	Histidine kinase
C9888_RS07160	COG0436	Aminotransferase
C9888_RS07170	COG0835	chemotaxis
C9888_RS07170	COG0784	Response regulator, receiver
C9888_RS07180	COG2814	Major facilitator Superfamily
C9888_RS07185	COG1376	ErfK ybiS ycfS ynhG family protein
C9888_RS07190	COG1408	metallophosphoesterase
C9888_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS07205	COG2200	EAL domain
C9888_RS07215	COG4703	Protein of unknown function (DUF1797)
C9888_RS07220	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C9888_RS07230	COG0517	IMP dehydrogenase activity
C9888_RS07235	COG0583	DNA-binding transcription factor activity
C9888_RS07240	COG0716	FMN binding
C9888_RS07250	COG0716	FMN binding
C9888_RS07270	COG0668	transmembrane transport
C9888_RS07275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS07295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9888_RS07300	COG0303	'Molybdopterin
C9888_RS07305	COG1763	Mo-molybdopterin cofactor biosynthetic process
C9888_RS07310	COG0314	molybdopterin synthase activity
C9888_RS07315	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9888_RS07325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9888_RS07330	COG1136	(ABC) transporter
C9888_RS07335	COG0577	efflux transmembrane transporter activity
C9888_RS07340	COG1349	DNA-binding transcription factor activity
C9888_RS07345	COG1105	Belongs to the carbohydrate kinase PfkB family
C9888_RS07350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS07350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9888_RS07350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9888_RS07355	COG0681	Belongs to the peptidase S26 family
C9888_RS07365	COG0488	(ABC) transporter
C9888_RS07370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9888_RS07375	COG2309	aminopeptidase activity
C9888_RS07385	COG1077	Cell shape determining protein MreB Mrl
C9888_RS07395	COG2002	toxin-antitoxin pair type II binding
C9888_RS07400	COG3852	Histidine kinase
C9888_RS07405	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
C9888_RS07405	COG2105	PFAM AIG2 family protein
C9888_RS07410	COG0569	domain protein
C9888_RS07420	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C9888_RS07430	COG0561	phosphatase activity
C9888_RS07435	COG0242	peptide deformylase activity
C9888_RS07445	COG0497	DNA recombination
C9888_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS07460	COG4221	oxidoreductase activity
C9888_RS07460	COG3321	synthase
C9888_RS07460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS07465	COG3321	synthase
C9888_RS07465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS07465	COG4221	oxidoreductase activity
C9888_RS07465	COG0300	oxidoreductase activity
C9888_RS07470	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS07470	COG3321	synthase
C9888_RS07470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS07470	COG4221	oxidoreductase activity
C9888_RS07475	COG4221	oxidoreductase activity
C9888_RS07475	COG3321	synthase
C9888_RS07475	COG0300	oxidoreductase activity
C9888_RS07475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS07480	COG3321	synthase
C9888_RS07480	COG4221	oxidoreductase activity
C9888_RS07480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS07480	COG0300	oxidoreductase activity
C9888_RS07485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS07485	COG0300	oxidoreductase activity
C9888_RS07485	COG3321	synthase
C9888_RS07485	COG4221	oxidoreductase activity
C9888_RS07490	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS07490	COG3321	synthase
C9888_RS07490	COG4221	oxidoreductase activity
C9888_RS07490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS07495	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9888_RS07500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C9888_RS07505	COG0022	dehydrogenase e1 component
C9888_RS07510	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9888_RS07515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9888_RS07520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS07535	COG1982	Orn Lys Arg decarboxylase major
C9888_RS07560	COG0483	inositol monophosphate 1-phosphatase activity
C9888_RS07570	COG3227	Zinc metalloprotease (Elastase)
C9888_RS07595	COG1217	gtp-binding protein TYPA
C9888_RS07605	COG4896	Protein conserved in bacteria
C9888_RS07615	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C9888_RS07620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C9888_RS07705	COG0457	Tetratricopeptide repeat
C9888_RS07720	COG2433	Pfam Transposase IS66
C9888_RS07730	COG0739	heme binding
C9888_RS07730	COG0741	lytic transglycosylase activity
C9888_RS07730	COG1196	nuclear chromosome segregation
C9888_RS07845	COG0772	Belongs to the SEDS family
C9888_RS07850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C9888_RS07865	COG2010	Cytochrome c
C9888_RS07865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9888_RS07870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9888_RS07875	COG1845	cytochrome c oxidase, subunit III
C9888_RS07880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9888_RS07885	COG3336	cytochrome c oxidase
C9888_RS07895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C9888_RS07900	COG2340	Cysteine-rich secretory protein family
C9888_RS07915	COG3679	Belongs to the UPF0342 family
C9888_RS07930	COG0742	ribosomal rna small subunit methyltransferase
C9888_RS07940	COG3314	Sporulation integral membrane protein YlbJ
C9888_RS07945	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9888_RS07950	COG3480	Lon protease (S16) C-terminal proteolytic domain
C9888_RS07960	COG1399	metal-binding, possibly nucleic acid-binding protein
C9888_RS07980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9888_RS08000	COG4839	cell division protein FtsL
C9888_RS08005	COG0768	penicillin binding
C9888_RS08010	COG0768	penicillin binding
C9888_RS08030	COG0772	Belongs to the SEDS family
C9888_RS08045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9888_RS08050	COG0849	cell division
C9888_RS08055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9888_RS08060	COG4412	M6 family metalloprotease domain protein
C9888_RS08060	COG1404	Belongs to the peptidase S8 family
C9888_RS08070	COG1191	sigma factor activity
C9888_RS08075	COG1191	sigma factor activity
C9888_RS08080	COG1119	ATPase activity
C9888_RS08085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9888_RS08090	COG1873	PFAM PRC-barrel domain
C9888_RS08095	COG1496	oxidoreductase activity
C9888_RS08100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9888_RS08110	COG0762	integral membrane protein
C9888_RS08115	COG2302	S4 RNA-binding domain
C9888_RS08120	COG3599	regulation of cell shape
C9888_RS08130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9888_RS08135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9888_RS08145	COG0564	pseudouridine synthase activity
C9888_RS08155	COG2233	PERMEase
C9888_RS08165	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C9888_RS08170	COG0505	Belongs to the CarA family
C9888_RS08175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9888_RS08190	COG0284	orotidine-5'-phosphate decarboxylase activity
C9888_RS08195	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C9888_RS08205	COG0306	phosphate transporter
C9888_RS08220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9888_RS08225	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C9888_RS08230	COG1648	precorrin-2 dehydrogenase activity
C9888_RS08245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C9888_RS08250	COG1561	YicC-like family, N-terminal region
C9888_RS08260	COG0194	GDP metabolic process
C9888_RS08270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9888_RS08275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9888_RS08280	COG0242	peptide deformylase activity
C9888_RS08290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9888_RS08290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9888_RS08300	COG0631	protein serine/threonine phosphatase activity
C9888_RS08305	COG2815	serine threonine protein kinase
C9888_RS08305	COG0515	serine threonine protein kinase
C9888_RS08315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9888_RS08320	COG1564	THIamine pyrophosphokinase
C9888_RS08335	COG1302	Protein conserved in bacteria
C9888_RS08340	COG1461	Dihydroxyacetone kinase
C9888_RS08345	COG1760	l-serine dehydratase
C9888_RS08350	COG1760	l-serine dehydratase
C9888_RS08355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C9888_RS08370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9888_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS08390	COG1196	nuclear chromosome segregation
C9888_RS08395	COG0552	protein localization to endoplasmic reticulum
C9888_RS08410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9888_RS08420	COG1837	Belongs to the UPF0109 family
C9888_RS08445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C9888_RS08460	COG2257	FlhB HrpN YscU SpaS Family
C9888_RS08470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C9888_RS08475	COG0758	DNA mediated transformation
C9888_RS08490	COG4974	Belongs to the 'phage' integrase family
C9888_RS08510	COG1815	bacterial-type flagellum-dependent cell motility
C9888_RS08515	COG1558	bacterial-type flagellum-dependent cell motility
C9888_RS08520	COG1677	Flagellar hook-basal body complex protein FliE
C9888_RS08525	COG1766	The M ring may be actively involved in energy transduction
C9888_RS08530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9888_RS08535	COG1317	bacterial-type flagellum organization
C9888_RS08540	COG1157	protein secretion by the type III secretion system
C9888_RS08545	COG2882	bacterial-type flagellum organization
C9888_RS08550	COG3334	PFAM MgtE intracellular
C9888_RS08555	COG3144	bacterial-type flagellum assembly
C9888_RS08560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9888_RS08565	COG4786	Flagellar basal body rod
C9888_RS08570	COG1582	Flagellar protein (FlbD)
C9888_RS08575	COG1580	Controls the rotational direction of flagella during chemotaxis
C9888_RS08580	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9888_RS08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9888_RS08585	COG1776	CheC inhibitor of MCP methylation
C9888_RS08590	COG2201	protein-glutamate methylesterase activity
C9888_RS08595	COG3190	flagellar
C9888_RS08600	COG1338	Plays a role in the flagellum-specific transport system
C9888_RS08605	COG1987	bacterial-type flagellum assembly
C9888_RS08610	COG1684	flagellar biosynthetic protein fliR
C9888_RS08615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9888_RS08620	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9888_RS08625	COG1419	protein localization to endoplasmic reticulum
C9888_RS08630	COG0455	bacterial-type flagellum organization
C9888_RS08635	COG2201	protein-glutamate methylesterase activity
C9888_RS08640	COG0643	Histidine kinase
C9888_RS08640	COG2198	Histidine kinase
C9888_RS08645	COG0835	chemotaxis
C9888_RS08650	COG1776	CheC inhibitor of MCP methylation
C9888_RS08660	COG1191	sigma factor activity
C9888_RS08690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9888_RS08695	COG4589	Belongs to the CDS family
C9888_RS08705	COG0750	zinc metalloprotease
C9888_RS08715	COG2176	DNA-directed DNA polymerase activity
C9888_RS08725	COG0195	Participates in both transcription termination and antitermination
C9888_RS08730	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C9888_RS08735	COG1358	cellular component organization or biogenesis
C9888_RS08745	COG1550	Protein conserved in bacteria
C9888_RS08760	COG0196	riboflavin kinase activity
C9888_RS08775	COG0726	polysaccharide deacetylase
C9888_RS08780	COG0612	Peptidase, M16
C9888_RS08785	COG1873	PFAM PRC-barrel domain
C9888_RS08790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9888_RS08795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9888_RS08800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9888_RS08805	COG0527	aspartate kinase activity
C9888_RS08815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C9888_RS08820	COG0740	serine-type endopeptidase activity
C9888_RS08830	COG1674	ftsk spoiiie
C9888_RS08830	COG4980	gas vesicle protein
C9888_RS08835	COG2188	Transcriptional regulator
C9888_RS08840	COG2814	Major facilitator Superfamily
C9888_RS08845	COG1846	Transcriptional regulator
C9888_RS08850	COG1033	growth of symbiont in host cell
C9888_RS08850	COG2409	Drug exporters of the RND superfamily
C9888_RS08855	COG0612	Peptidase, M16
C9888_RS08860	COG0612	Peptidase, M16
C9888_RS08865	COG0300	oxidoreductase activity
C9888_RS08880	COG1426	Protein conserved in bacteria
C9888_RS08885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9888_RS08900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C9888_RS08910	COG1692	metallophosphoesterase
C9888_RS08915	COG2359	stage V sporulation protein S
C9888_RS08935	COG4550	Control of competence regulator ComK, YlbF/YmcA
C9888_RS09010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS09015	COG3425	synthase
C9888_RS09020	COG1024	Enoyl-CoA hydratase
C9888_RS09025	COG1024	Enoyl-CoA hydratase
C9888_RS09030	COG0300	oxidoreductase activity
C9888_RS09030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS09030	COG3321	synthase
C9888_RS09030	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS09035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS09035	COG0300	oxidoreductase activity
C9888_RS09035	COG4221	oxidoreductase activity
C9888_RS09035	COG3321	synthase
C9888_RS09040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS09040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS09040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS09040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS09040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS09040	COG3321	synthase
C9888_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS09040	COG3321	synthase
C9888_RS09040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS09045	COG4221	oxidoreductase activity
C9888_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS09045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS09045	COG3321	synthase
C9888_RS09050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9888_RS09050	COG3321	synthase
C9888_RS09050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS09050	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C9888_RS09055	COG2124	cytochrome p450
C9888_RS09065	COG3619	membrane
C9888_RS09075	COG1404	Belongs to the peptidase S8 family
C9888_RS09085	COG4195	phage-related replication protein
C9888_RS09090	COG1764	response to oxidative stress
C9888_RS09100	COG2076	Multidrug Resistance protein
C9888_RS09140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9888_RS09145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9888_RS09150	COG4112	unkown
C9888_RS09155	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9888_RS09165	COG0464	growth
C9888_RS09170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9888_RS09175	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C9888_RS09180	COG0789	Transcriptional regulator
C9888_RS09185	COG0174	glutamine synthetase
C9888_RS09190	COG0582	viral genome integration into host DNA
C9888_RS09200	COG1525	nuclease
C9888_RS09205	COG5444	nuclease activity
C9888_RS09245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9888_RS09250	COG0457	Tetratricopeptide repeat
C9888_RS09275	COG5632	N-Acetylmuramoyl-L-alanine amidase
C9888_RS09275	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS09280	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS09290	COG2433	Pfam Transposase IS66
C9888_RS09470	COG0776	regulation of translation
C9888_RS09580	COG3655	Transcriptional regulator
C9888_RS09585	COG3655	Transcriptional regulator
C9888_RS09675	COG3655	Transcriptional regulator
C9888_RS09770	COG1793	dna ligase
C9888_RS09775	COG2135	peptidase activity
C9888_RS09790	COG4195	phage-related replication protein
C9888_RS09795	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS09795	COG3420	alginic acid biosynthetic process
C9888_RS09820	COG2887	Belongs to the helicase family. UvrD subfamily
C9888_RS09830	COG0305	Participates in initiation and elongation during chromosome replication
C9888_RS09835	COG0358	DNA primase activity
C9888_RS09840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9888_RS09845	COG0587	DNA-directed DNA polymerase activity
C9888_RS09850	COG3584	3D domain protein
C9888_RS09860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C9888_RS09985	COG1780	Probably involved in ribonucleotide reductase function
C9888_RS09990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9888_RS09990	COG1372	Participates in initiation and elongation during chromosome replication
C9888_RS10000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9888_RS10005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS10020	COG0756	dUTP diphosphatase activity
C9888_RS10040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C9888_RS10080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9888_RS10130	COG3331	DNA recombination
C9888_RS10170	COG2211	Major facilitator Superfamily
C9888_RS10175	COG3507	Belongs to the glycosyl hydrolase 43 family
C9888_RS10190	COG1070	Carbohydrate kinase
C9888_RS10195	COG3848	Pyruvate phosphate dikinase
C9888_RS10195	COG0574	Belongs to the PEP-utilizing enzyme family
C9888_RS10220	COG2378	regulation of single-species biofilm formation
C9888_RS10225	COG2318	DinB family
C9888_RS10230	COG1064	alcohol dehydrogenase
C9888_RS10255	COG0456	acetyltransferase
C9888_RS10260	COG5444	nuclease activity
C9888_RS10320	COG3397	chitin binding
C9888_RS10330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS10340	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS10350	COG0756	dUTP diphosphatase activity
C9888_RS10355	COG4195	phage-related replication protein
C9888_RS10385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C9888_RS10395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9888_RS10415	COG0785	Cytochrome C biogenesis protein
C9888_RS10420	COG2201	protein-glutamate methylesterase activity
C9888_RS10425	COG4846	Membrane protein involved in cytochrome C biogenesis
C9888_RS10435	COG0071	Belongs to the small heat shock protein (HSP20) family
C9888_RS10450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C9888_RS10455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS10475	COG0824	Thioesterase
C9888_RS10485	COG4841	protein insertion into membrane
C9888_RS10495	COG1832	CoA-binding protein
C9888_RS10500	COG0187	DNA topoisomerase II activity
C9888_RS10505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C9888_RS10515	COG1115	amino acid carrier protein
C9888_RS10525	COG1063	alcohol dehydrogenase
C9888_RS10530	COG0800	Aldolase
C9888_RS10535	COG1312	Catalyzes the dehydration of D-mannonate
C9888_RS10540	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS10545	COG1609	Transcriptional regulator
C9888_RS10550	COG2271	Major facilitator Superfamily
C9888_RS10595	COG2205	protein histidine kinase activity
C9888_RS10600	COG0745	RESPONSE REGULATOR receiver
C9888_RS10610	COG3507	Belongs to the glycosyl hydrolase 43 family
C9888_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS10640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C9888_RS10645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C9888_RS10650	COG2610	gluconate transmembrane transporter activity
C9888_RS10655	COG2124	cytochrome p450
C9888_RS10675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9888_RS10685	COG2246	polysaccharide biosynthetic process
C9888_RS10690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9888_RS10695	COG0586	Pfam SNARE associated Golgi protein
C9888_RS10700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9888_RS10705	COG1024	Enoyl-CoA hydratase
C9888_RS10710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9888_RS10715	COG0511	ligase activity, forming carbon-carbon bonds
C9888_RS10720	COG0439	Biotin carboxylase
C9888_RS10725	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS10730	COG1960	acyl-CoA dehydrogenase activity
C9888_RS10735	COG1649	PFAM Uncharacterised BCR, COG1649
C9888_RS10745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C9888_RS10745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS10750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS10760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS10765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS10775	COG2027	D-alanyl-D-alanine carboxypeptidase
C9888_RS10780	COG2017	converts alpha-aldose to the beta-anomer
C9888_RS10785	COG0534	Mate efflux family protein
C9888_RS10800	COG0582	viral genome integration into host DNA
C9888_RS10805	COG0166	Belongs to the GPI family
C9888_RS10810	COG0405	Gamma-glutamyltransferase
C9888_RS10815	COG2814	Major facilitator Superfamily
C9888_RS10820	COG0640	Transcriptional regulator
C9888_RS10825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9888_RS10835	COG0604	alcohol dehydrogenase
C9888_RS10845	COG0493	'glutamate synthase
C9888_RS10850	COG0070	glutamate synthase
C9888_RS10850	COG0069	glutamate synthase activity
C9888_RS10850	COG0067	glutamate synthase
C9888_RS10855	COG0583	DNA-binding transcription factor activity
C9888_RS10860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9888_RS10880	COG0300	oxidoreductase activity
C9888_RS10885	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C9888_RS10895	COG2814	Major facilitator Superfamily
C9888_RS10900	COG1070	Carbohydrate kinase
C9888_RS10905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9888_RS10910	COG0243	molybdopterin cofactor binding
C9888_RS10945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9888_RS10950	COG2207	Transcriptional regulator
C9888_RS10950	COG0662	Cupin 2, conserved barrel domain protein
C9888_RS10955	COG1309	transcriptional regulator
C9888_RS10960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS10970	COG0640	Transcriptional regulator
C9888_RS10975	COG0741	lytic transglycosylase activity
C9888_RS10980	COG2322	membrane
C9888_RS10995	COG1619	proteins homologs of microcin C7 resistance protein MccF
C9888_RS11005	COG1388	LysM domain
C9888_RS11005	COG3584	3D domain protein
C9888_RS11010	COG0514	ATP-dependent DNA helicase (RecQ)
C9888_RS11020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9888_RS11025	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9888_RS11040	COG0071	Belongs to the small heat shock protein (HSP20) family
C9888_RS11075	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS11080	COG1657	PFAM Prenyltransferase squalene oxidase
C9888_RS11085	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9888_RS11090	COG0733	neurotransmitter:sodium symporter activity
C9888_RS11095	COG0385	Bile acid
C9888_RS11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9888_RS11115	COG4548	von Willebrand factor, type A
C9888_RS11120	COG0714	Associated with various cellular activities
C9888_RS11125	COG2032	superoxide dismutase activity
C9888_RS11130	COG1388	LysM domain
C9888_RS11130	COG0791	NLP P60 protein
C9888_RS11135	COG1819	glycosyl
C9888_RS11140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C9888_RS11145	COG0534	Mate efflux family protein
C9888_RS11150	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS11155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C9888_RS11160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C9888_RS11170	COG2962	Rard protein
C9888_RS11185	COG1942	4-Oxalocrotonate Tautomerase
C9888_RS11195	COG1733	regulation of RNA biosynthetic process
C9888_RS11200	COG0778	Nitroreductase
C9888_RS11205	COG0400	carboxylic ester hydrolase activity
C9888_RS11210	COG0346	lactoylglutathione lyase activity
C9888_RS11220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9888_RS11230	COG2723	6-phospho-beta-galactosidase activity
C9888_RS11235	COG2188	Transcriptional regulator
C9888_RS11240	COG0793	Belongs to the peptidase S41A family
C9888_RS11240	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS11245	COG2226	methyltransferase
C9888_RS11255	COG1876	peptidase activity
C9888_RS11275	COG0671	phosphoesterase, PA-phosphatase related
C9888_RS11305	COG1509	lysine 2,3-aminomutase activity
C9888_RS11310	COG0456	acetyltransferase
C9888_RS11315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9888_RS11320	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C9888_RS11325	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C9888_RS11330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9888_RS11335	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C9888_RS11345	COG0456	acetyltransferase
C9888_RS11350	COG0463	Glycosyl transferase, family 2
C9888_RS11365	COG4641	Protein conserved in bacteria
C9888_RS11375	COG1086	Polysaccharide biosynthesis protein
C9888_RS11390	COG1846	Transcriptional regulator
C9888_RS11395	COG4698	Protein conserved in bacteria
C9888_RS11400	COG2755	lipolytic protein G-D-S-L family
C9888_RS11405	COG1999	signal sequence binding
C9888_RS11415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C9888_RS11420	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C9888_RS11425	COG1272	protein, Hemolysin III
C9888_RS11430	COG0204	Acyl-transferase
C9888_RS11435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9888_RS11450	COG2521	methyltransferase
C9888_RS11450	COG2136	Putative SAM-dependent methyltransferase
C9888_RS11465	COG1413	lyase activity
C9888_RS11470	COG1418	mRNA catabolic process
C9888_RS11475	COG0386	Belongs to the glutathione peroxidase family
C9888_RS11485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9888_RS11490	COG1278	Cold shock
C9888_RS11510	COG0328	RNA-DNA hybrid ribonuclease activity
C9888_RS11515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C9888_RS11520	COG0328	RNA-DNA hybrid ribonuclease activity
C9888_RS11530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9888_RS11545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C9888_RS11555	COG1755	Isoprenylcysteine carboxyl methyltransferase
C9888_RS11560	COG3424	synthase
C9888_RS11585	COG1335	isochorismatase
C9888_RS11625	COG4824	toxin secretion phage lysis holin
C9888_RS11645	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS11650	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9888_RS11660	COG5280	Phage tail tape measure protein TP901
C9888_RS11660	COG3953	SLT domain
C9888_RS11750	COG1595	DNA-templated transcription, initiation
C9888_RS11775	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C9888_RS11780	COG1484	DNA-dependent DNA replication
C9888_RS11785	COG3935	DnaD domain protein
C9888_RS11825	COG3646	Phage regulatory protein
C9888_RS11825	COG3645	SOS response
C9888_RS11840	COG3620	sequence-specific DNA binding
C9888_RS11845	COG0582	viral genome integration into host DNA
C9888_RS11850	COG2233	PERMEase
C9888_RS11860	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C9888_RS11865	COG1199	ATP-dependent helicase activity
C9888_RS11880	COG0116	Belongs to the methyltransferase superfamily
C9888_RS11905	COG3359	exonuclease
C9888_RS11910	COG1111	helicase
C9888_RS11910	COG1205	dead DEAH box helicase
C9888_RS11915	COG2190	(PTS) system
C9888_RS11920	COG0071	Belongs to the small heat shock protein (HSP20) family
C9888_RS11960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9888_RS11960	COG4499	WXG100 protein secretion system (Wss), protein YukC
C9888_RS11970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9888_RS11975	COG3935	DnaD domain protein
C9888_RS11985	COG0436	Aminotransferase
C9888_RS11990	COG5353	protein conserved in bacteria
C9888_RS12000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9888_RS12000	COG1199	ATP-dependent helicase activity
C9888_RS12030	COG0438	transferase activity, transferring glycosyl groups
C9888_RS12035	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C9888_RS12050	COG1694	Mazg nucleotide pyrophosphohydrolase
C9888_RS12055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS12060	COG2140	Oxalate decarboxylase
C9888_RS12070	COG4347	Protein of unknown function (DUF1405)
C9888_RS12075	COG2010	Cytochrome c
C9888_RS12075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9888_RS12080	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9888_RS12085	COG0723	plastoquinol--plastocyanin reductase activity
C9888_RS12100	COG0457	Tetratricopeptide repeat
C9888_RS12110	COG0287	Prephenate dehydrogenase
C9888_RS12145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9888_RS12150	COG4401	Chorismate mutase type I
C9888_RS12165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9888_RS12170	COG0105	UTP biosynthetic process
C9888_RS12175	COG0142	geranyltranstransferase activity
C9888_RS12185	COG0142	geranyltranstransferase activity
C9888_RS12200	COG0776	regulation of translation
C9888_RS12205	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C9888_RS12245	COG0539	negative regulation of cytoplasmic translation
C9888_RS12255	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C9888_RS12260	COG2959	enzyme of heme biosynthesis
C9888_RS12265	COG3773	Cell wall hydrolase
C9888_RS12265	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS12270	COG2339	peptidase activity
C9888_RS12275	COG0492	ferredoxin-NADP+ reductase activity
C9888_RS12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9888_RS12285	COG4862	establishment of competence for transformation
C9888_RS12290	COG1408	metallophosphoesterase
C9888_RS12300	COG1388	LysM domain
C9888_RS12305	COG1266	CAAX protease self-immunity
C9888_RS12310	COG0514	ATP-dependent DNA helicase (RecQ)
C9888_RS12315	COG4955	Helix-turn-helix domain
C9888_RS12320	COG1141	Ferredoxin
C9888_RS12325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C9888_RS12330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9888_RS12340	COG1595	DNA-templated transcription, initiation
C9888_RS12345	COG5002	protein histidine kinase activity
C9888_RS12350	COG0745	RESPONSE REGULATOR receiver
C9888_RS12355	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9888_RS12360	COG1333	cytochrome c biogenesis protein
C9888_RS12365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS12370	COG1187	pseudouridine synthase activity
C9888_RS12375	COG0700	Nucleoside recognition
C9888_RS12380	COG2715	membrane protein required for spore maturation
C9888_RS12385	COG1686	Belongs to the peptidase S11 family
C9888_RS12410	COG1547	Domain of unknown function (DUF309)
C9888_RS12420	COG0456	acetyltransferase
C9888_RS12435	COG0307	riboflavin synthase, alpha
C9888_RS12440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9888_RS12440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9888_RS12450	COG0681	Belongs to the peptidase S26 family
C9888_RS12460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9888_RS12465	COG4086	secreted protein
C9888_RS12470	COG0019	diaminopimelate decarboxylase activity
C9888_RS12475	COG0697	spore germination
C9888_RS12490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9888_RS12510	COG1191	sigma factor activity
C9888_RS12520	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS12525	COG1686	Belongs to the peptidase S11 family
C9888_RS12530	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C9888_RS12535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C9888_RS12540	COG4974	Belongs to the 'phage' integrase family
C9888_RS12550	COG0735	belongs to the Fur family
C9888_RS12555	COG1300	Membrane
C9888_RS12570	COG0281	malic enzyme
C9888_RS12575	COG1757	Na H antiporter
C9888_RS12580	COG1027	Aspartate ammonia-lyase
C9888_RS12585	COG0252	asparaginase activity
C9888_RS12590	COG1396	sequence-specific DNA binding
C9888_RS12595	COG1379	DNA repair
C9888_RS12600	COG0494	nUDIX hydrolase
C9888_RS12610	COG0667	Aldo Keto reductase
C9888_RS12620	COG1073	alpha beta
C9888_RS12630	COG4918	Iron-sulphur cluster biosynthesis
C9888_RS12635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C9888_RS12635	COG0456	acetyltransferase
C9888_RS12640	COG2329	Antibiotic biosynthesis monooxygenase
C9888_RS12645	COG0456	acetyltransferase
C9888_RS12650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9888_RS12665	COG0628	permease
C9888_RS12675	COG0346	lactoylglutathione lyase activity
C9888_RS12685	COG3048	D-serine ammonia-lyase activity
C9888_RS12690	COG0300	oxidoreductase activity
C9888_RS12695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS12700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9888_RS12705	COG1024	Enoyl-CoA hydratase
C9888_RS12710	COG3425	synthase
C9888_RS12715	COG2124	cytochrome p450
C9888_RS12720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS12720	COG3321	synthase
C9888_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS12725	COG3321	synthase
C9888_RS12725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS12725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS12725	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12730	COG3321	synthase
C9888_RS12730	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12730	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS12730	COG0300	oxidoreductase activity
C9888_RS12730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12735	COG0300	oxidoreductase activity
C9888_RS12735	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12735	COG3321	synthase
C9888_RS12740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS12740	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS12740	COG3321	synthase
C9888_RS12740	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12745	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS12745	COG0300	oxidoreductase activity
C9888_RS12745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12745	COG3321	synthase
C9888_RS12750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9888_RS12750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9888_RS12750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12750	COG3321	synthase
C9888_RS12755	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS12760	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS12775	COG2070	2-Nitropropane dioxygenase
C9888_RS12775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C9888_RS12780	COG0250	Participates in transcription elongation, termination and antitermination
C9888_RS12805	COG0596	Alpha beta hydrolase
C9888_RS12820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9888_RS12825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9888_RS12840	COG0706	membrane insertase activity
C9888_RS12845	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9888_RS12850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9888_RS12855	COG0346	lactoylglutathione lyase activity
C9888_RS12860	COG1376	ErfK ybiS ycfS ynhG family protein
C9888_RS12865	COG4129	membrane
C9888_RS12870	COG1126	abc transporter atp-binding protein
C9888_RS12875	COG0765	amino acid transport
C9888_RS12880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS12890	COG1597	lipid kinase activity
C9888_RS12895	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9888_RS12900	COG0022	dehydrogenase e1 component
C9888_RS12905	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C9888_RS12910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9888_RS12915	COG3426	butyrate kinase activity
C9888_RS12920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9888_RS12925	COG0280	phosphate acetyltransferase
C9888_RS12930	COG3829	transcription factor binding
C9888_RS12930	COG3290	protein histidine kinase activity
C9888_RS12940	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C9888_RS12945	COG2079	MmgE PrpD family protein
C9888_RS12950	COG0372	Belongs to the citrate synthase family
C9888_RS12955	COG1960	acyl-CoA dehydrogenase activity
C9888_RS12960	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9888_RS12965	COG0183	Belongs to the thiolase family
C9888_RS12970	COG0584	glycerophosphoryl diester phosphodiesterase
C9888_RS12995	COG1902	pentaerythritol trinitrate reductase activity
C9888_RS13010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9888_RS13015	COG0745	RESPONSE REGULATOR receiver
C9888_RS13020	COG0750	zinc metalloprotease
C9888_RS13025	COG0497	DNA recombination
C9888_RS13035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C9888_RS13045	COG0142	geranyltranstransferase activity
C9888_RS13055	COG1570	exodeoxyribonuclease VII activity
C9888_RS13070	COG1302	Protein conserved in bacteria
C9888_RS13075	COG0439	Biotin carboxylase
C9888_RS13080	COG0511	ligase activity, forming carbon-carbon bonds
C9888_RS13120	COG3854	ATPases associated with a variety of cellular activities
C9888_RS13135	COG0006	proline dipeptidase activity
C9888_RS13145	COG3872	metal-dependent enzyme
C9888_RS13155	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9888_RS13170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9888_RS13190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9888_RS13205	COG1396	sequence-specific DNA binding
C9888_RS13215	COG0681	Belongs to the peptidase S26 family
C9888_RS13240	COG4940	Competence protein ComGF
C9888_RS13250	COG4970	Tfp pilus assembly protein FimT
C9888_RS13255	COG4537	Required for transformation and DNA binding
C9888_RS13260	COG1459	type II secretion system
C9888_RS13265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9888_RS13270	COG0598	Magnesium transport protein CorA
C9888_RS13275	COG1253	flavin adenine dinucleotide binding
C9888_RS13280	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS13290	COG1393	Belongs to the ArsC family
C9888_RS13300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS13310	COG0011	TIGRFAM Protein of
C9888_RS13320	COG2866	Carboxypeptidase
C9888_RS13325	COG1940	carbohydrate kinase activity
C9888_RS13330	COG4483	Protein conserved in bacteria
C9888_RS13335	COG1757	Na H antiporter
C9888_RS13345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9888_RS13360	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9888_RS13365	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9888_RS13370	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9888_RS13375	COG0581	inorganic phosphate transmembrane transporter activity
C9888_RS13380	COG0573	inorganic phosphate transmembrane transporter activity
C9888_RS13385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9888_RS13390	COG0768	penicillin binding
C9888_RS13395	COG0477	Major facilitator Superfamily
C9888_RS13400	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C9888_RS13405	COG2839	Protein conserved in bacteria
C9888_RS13410	COG5521	maltodextrose utilization protein MalA
C9888_RS13415	COG1388	LysM domain
C9888_RS13425	COG4709	membrane
C9888_RS13430	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C9888_RS13435	COG0735	belongs to the Fur family
C9888_RS13440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS13455	COG0513	Belongs to the DEAD box helicase family
C9888_RS13470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9888_RS13475	COG2384	SAM-dependent methyltransferase
C9888_RS13480	COG2010	Cytochrome c
C9888_RS13485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9888_RS13490	COG0358	DNA primase activity
C9888_RS13505	COG0517	IMP dehydrogenase activity
C9888_RS13510	COG0751	glycine-tRNA ligase activity
C9888_RS13530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9888_RS13535	COG0295	cytidine deaminase activity
C9888_RS13540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9888_RS13550	COG1480	7TM receptor with intracellular HD hydrolase
C9888_RS13555	COG1702	phosphate starvation-inducible protein PhoH
C9888_RS13560	COG0561	phosphatase activity
C9888_RS13575	COG4864	UPF0365 protein
C9888_RS13580	COG1030	water channel activity
C9888_RS13585	COG1610	YqeY-like protein
C9888_RS13595	COG1283	sodium-dependent phosphate transmembrane transporter activity
C9888_RS13600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9888_RS13605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9888_RS13635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9888_RS13650	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9888_RS13665	COG1466	dna polymerase III delta subunit
C9888_RS13675	COG2333	competence protein COMEC
C9888_RS13675	COG0658	competence protein
C9888_RS13680	COG2131	deaminase
C9888_RS13685	COG1596	polysaccharide export
C9888_RS13685	COG1555	photosystem II stabilization
C9888_RS13690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9888_RS13695	COG2226	methyltransferase
C9888_RS13700	COG0799	negative regulation of ribosome biogenesis
C9888_RS13705	COG1713	HD superfamily hydrolase involved in NAD metabolism
C9888_RS13715	COG1534	Rna-binding protein
C9888_RS13720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9888_RS13725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C9888_RS13730	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C9888_RS13740	COG2755	lipolytic protein G-D-S-L family
C9888_RS13750	COG0398	Pfam SNARE associated Golgi protein
C9888_RS13795	COG3708	Transcriptional regulator
C9888_RS13795	COG2207	Transcriptional regulator
C9888_RS13800	COG0583	DNA-binding transcription factor activity
C9888_RS13815	COG5002	protein histidine kinase activity
C9888_RS13815	COG0642	Histidine kinase
C9888_RS13820	COG0745	RESPONSE REGULATOR receiver
C9888_RS13825	COG2311	Membrane
C9888_RS13830	COG0454	-acetyltransferase
C9888_RS13835	COG0563	adenylate kinase activity
C9888_RS13845	COG2814	Major facilitator Superfamily
C9888_RS13855	COG0456	acetyltransferase
C9888_RS13860	COG2318	DinB family
C9888_RS13870	COG0561	phosphatase activity
C9888_RS13875	COG0561	phosphatase activity
C9888_RS13885	COG1482	cell wall glycoprotein biosynthetic process
C9888_RS13890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9888_RS13890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS13890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9888_RS13895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS13895	COG3711	transcriptional antiterminator
C9888_RS13905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9888_RS13910	COG0583	DNA-binding transcription factor activity
C9888_RS13915	COG2814	Major facilitator Superfamily
C9888_RS13920	COG2124	cytochrome p450
C9888_RS13920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9888_RS13925	COG1309	transcriptional regulator
C9888_RS13930	COG2226	methyltransferase
C9888_RS13945	COG2116	formate transmembrane transporter activity
C9888_RS13950	COG5609	conserved protein (DUF2294)
C9888_RS13955	COG3383	formate dehydrogenase (NAD+) activity
C9888_RS13960	COG2427	Protein of unknown function (DUF1641)
C9888_RS13970	COG0626	cystathionine gamma-synthase activity
C9888_RS13975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9888_RS14000	COG0768	penicillin binding
C9888_RS14035	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS14035	COG5632	N-Acetylmuramoyl-L-alanine amidase
C9888_RS14040	COG4824	toxin secretion phage lysis holin
C9888_RS14060	COG5434	Belongs to the glycosyl hydrolase 28 family
C9888_RS14065	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9888_RS14075	COG3953	SLT domain
C9888_RS14075	COG5280	Phage tail tape measure protein TP901
C9888_RS14160	COG0582	viral genome integration into host DNA
C9888_RS14165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C9888_RS14270	COG1396	sequence-specific DNA binding
C9888_RS14295	COG0826	peptidase U32
C9888_RS14300	COG0826	peptidase U32
C9888_RS14305	COG4122	O-methyltransferase activity
C9888_RS14310	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9888_RS14325	COG4472	Bacterial protein of unknown function (DUF965)
C9888_RS14335	COG0628	permease
C9888_RS14340	COG1126	abc transporter atp-binding protein
C9888_RS14345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS14350	COG0765	amino acid transport
C9888_RS14355	COG0765	amino acid transport
C9888_RS14370	COG3881	PFAM PRC-barrel domain
C9888_RS14375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9888_RS14380	COG0457	Tetratricopeptide repeat
C9888_RS14390	COG1104	cysteine desulfurase activity
C9888_RS14395	COG1959	2 iron, 2 sulfur cluster binding
C9888_RS14400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9888_RS14405	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9888_RS14425	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9888_RS14425	COG4991	sh3 domain protein
C9888_RS14425	COG3103	Sh3 type 3 domain protein
C9888_RS14435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9888_RS14445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9888_RS14445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C9888_RS14450	COG5416	Lipopolysaccharide assembly protein A domain
C9888_RS14455	COG0490	domain, Protein
C9888_RS14460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9888_RS14460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9888_RS14470	COG2244	polysaccharide biosynthetic process
C9888_RS14475	COG2323	membrane
C9888_RS14485	COG1862	Preprotein translocase
C9888_RS14530	COG1388	LysM domain
C9888_RS14540	COG0157	Belongs to the NadC ModD family
C9888_RS14545	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9888_RS14550	COG1104	cysteine desulfurase activity
C9888_RS14555	COG1827	regulation of RNA biosynthetic process
C9888_RS14560	COG0077	Prephenate dehydratase
C9888_RS14575	COG3290	protein histidine kinase activity
C9888_RS14580	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C9888_RS14585	COG2868	ribosomal protein
C9888_RS14595	COG1994	Peptidase M50
C9888_RS14600	COG0739	heme binding
C9888_RS14605	COG2894	cell division
C9888_RS14615	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C9888_RS14625	COG1077	Cell shape determining protein MreB Mrl
C9888_RS14645	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C9888_RS14650	COG0285	dihydrofolate synthase activity
C9888_RS14655	COG0525	valine-tRNA ligase activity
C9888_RS14665	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9888_RS14670	COG1388	LysM domain
C9888_RS14680	COG0113	porphobilinogen synthase activity
C9888_RS14685	COG1587	Uroporphyrinogen-III synthase
C9888_RS14695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9888_RS14715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9888_RS14720	COG1067	ATP-dependent peptidase activity
C9888_RS14720	COG0470	DNA polymerase III
C9888_RS14735	COG1477	protein flavinylation
C9888_RS14735	COG0457	Tetratricopeptide repeat
C9888_RS14750	COG0473	3-isopropylmalate dehydrogenase activity
C9888_RS14765	COG0440	acetolactate synthase activity
C9888_RS14770	COG0028	Belongs to the TPP enzyme family
C9888_RS14800	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
C9888_RS14825	COG0622	Phosphoesterase
C9888_RS14830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9888_RS14840	COG5401	PFAM Sporulation and spore germination
C9888_RS14850	COG1846	Transcriptional regulator
C9888_RS14855	COG2197	response regulator
C9888_RS14860	COG0824	Thioesterase
C9888_RS14865	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9888_RS14870	COG1053	succinate dehydrogenase
C9888_RS14875	COG2009	succinate dehydrogenase
C9888_RS14880	COG1719	4-vinyl reductase, 4VR
C9888_RS14885	COG0527	aspartate kinase activity
C9888_RS14900	COG3118	belongs to the thioredoxin family
C9888_RS14905	COG3534	alpha-L-arabinofuranosidase
C9888_RS14910	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C9888_RS14915	COG2086	electron transfer activity
C9888_RS14920	COG1024	Enoyl-CoA hydratase
C9888_RS14925	COG1309	transcriptional regulator
C9888_RS14930	COG0318	PFAM AMP-dependent synthetase and ligase
C9888_RS14940	COG3766	membrane
C9888_RS14950	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9888_RS14950	COG1796	DNA polymerase
C9888_RS14955	COG1286	toxin biosynthetic process
C9888_RS14970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9888_RS14970	COG0072	phenylalanine-tRNA ligase activity
C9888_RS14975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C9888_RS14980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9888_RS14990	COG3835	regulator
C9888_RS14995	COG0277	FAD linked oxidase domain protein
C9888_RS15000	COG0247	lactate metabolic process
C9888_RS15005	COG1966	Carbon starvation protein
C9888_RS15010	COG3534	alpha-L-arabinofuranosidase
C9888_RS15015	COG0395	ABC-type sugar transport system, permease component
C9888_RS15020	COG1175	transmembrane transport
C9888_RS15025	COG1653	transport
C9888_RS15035	COG0647	UMP catabolic process
C9888_RS15040	COG0235	Class ii aldolase
C9888_RS15045	COG1069	ribulokinase activity
C9888_RS15050	COG2160	L-arabinose isomerase activity
C9888_RS15055	COG3507	Belongs to the glycosyl hydrolase 43 family
C9888_RS15060	COG1363	Peptidase, m42
C9888_RS15070	COG3326	Membrane
C9888_RS15085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C9888_RS15090	COG1346	cytolysis
C9888_RS15095	COG1380	Effector of murein hydrolase LrgA
C9888_RS15100	COG3279	Response regulator of the LytR AlgR family
C9888_RS15105	COG3275	phosphorelay sensor kinase activity
C9888_RS15115	COG1011	Hydrolase
C9888_RS15130	COG0398	Pfam SNARE associated Golgi protein
C9888_RS15135	COG1484	DNA-dependent DNA replication
C9888_RS15140	COG3611	Membrane attachment protein
C9888_RS15155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9888_RS15160	COG1733	regulation of RNA biosynthetic process
C9888_RS15165	COG2814	Major facilitator Superfamily
C9888_RS15170	COG0656	L-ascorbic acid biosynthetic process
C9888_RS15175	COG0237	dephospho-CoA kinase activity
C9888_RS15180	COG1971	Probably functions as a manganese efflux pump
C9888_RS15185	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9888_RS15190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9888_RS15190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9888_RS15195	COG5002	protein histidine kinase activity
C9888_RS15200	COG0745	RESPONSE REGULATOR receiver
C9888_RS15210	COG0538	isocitrate dehydrogenase activity
C9888_RS15215	COG0372	Belongs to the citrate synthase family
C9888_RS15220	COG0457	Tetratricopeptide repeat
C9888_RS15250	COG0628	permease
C9888_RS15255	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9888_RS15260	COG0469	pyruvate kinase activity
C9888_RS15280	COG0281	malic enzyme
C9888_RS15285	COG0587	DNA-directed DNA polymerase activity
C9888_RS15305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C9888_RS15315	COG4109	DRTGG domain
C9888_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS15340	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9888_RS15350	COG0827	DNA restriction-modification system
C9888_RS15355	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C9888_RS15360	COG3874	Sporulation protein YtfJ
C9888_RS15370	COG1714	RDD family
C9888_RS15375	COG0616	signal peptide processing
C9888_RS15380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C9888_RS15385	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C9888_RS15390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9888_RS15405	COG1104	cysteine desulfurase activity
C9888_RS15410	COG1114	Component of the transport system for branched-chain amino acids
C9888_RS15420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9888_RS15425	COG1309	transcriptional regulator
C9888_RS15430	COG1956	GAF domain-containing protein
C9888_RS15435	COG2203	Gaf domain
C9888_RS15435	COG2199	diguanylate cyclase activity
C9888_RS15450	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS15455	COG4282	regulation of fungal-type cell wall biogenesis
C9888_RS15505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9888_RS15505	COG1017	nitric oxide dioxygenase activity
C9888_RS15515	COG0693	protein deglycase activity
C9888_RS15530	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C9888_RS15535	COG1378	Sugar-specific transcriptional regulator TrmB
C9888_RS15560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9888_RS15565	COG0454	-acetyltransferase
C9888_RS15570	COG0517	IMP dehydrogenase activity
C9888_RS15575	COG0123	including yeast histone deacetylase and acetoin utilization protein
C9888_RS15580	COG1360	Flagellar Motor Protein
C9888_RS15585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9888_RS15590	COG1609	Transcriptional regulator
C9888_RS15595	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C9888_RS15595	COG1605	Chorismate mutase
C9888_RS15600	COG3118	belongs to the thioredoxin family
C9888_RS15605	COG4980	gas vesicle protein
C9888_RS15610	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C9888_RS15620	COG1674	ftsk spoiiie
C9888_RS15625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9888_RS15635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS15655	COG1363	Peptidase, m42
C9888_RS15660	COG5584	Small secreted protein
C9888_RS15665	COG0281	malic enzyme
C9888_RS15670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9888_RS15685	COG0510	thiamine kinase activity
C9888_RS15690	COG1597	lipid kinase activity
C9888_RS15700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C9888_RS15705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9888_RS15710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9888_RS15715	COG2252	PERMEase
C9888_RS15720	COG4473	ABC transporter
C9888_RS15725	COG1131	(ABC) transporter
C9888_RS15730	COG1349	DNA-binding transcription factor activity
C9888_RS15735	COG1187	pseudouridine synthase activity
C9888_RS15740	COG2244	polysaccharide biosynthetic process
C9888_RS15745	COG2081	HI0933 family
C9888_RS15750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9888_RS15760	COG1609	Transcriptional regulator
C9888_RS15765	COG1653	transport
C9888_RS15770	COG1175	transmembrane transport
C9888_RS15775	COG0395	ABC-type sugar transport system, permease component
C9888_RS15780	COG1486	melibiose metabolic process
C9888_RS15790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9888_RS15805	COG1366	Belongs to the anti-sigma-factor antagonist family
C9888_RS15805	COG2202	Pas domain
C9888_RS15810	COG2814	Major facilitator Superfamily
C9888_RS15815	COG5522	Integral membrane protein (intg_mem_TP0381)
C9888_RS15820	COG0577	efflux transmembrane transporter activity
C9888_RS15825	COG1136	(ABC) transporter
C9888_RS15830	COG2205	protein histidine kinase activity
C9888_RS15835	COG0745	RESPONSE REGULATOR receiver
C9888_RS15840	COG0577	efflux transmembrane transporter activity
C9888_RS15845	COG1136	(ABC) transporter
C9888_RS15865	COG1131	(ABC) transporter
C9888_RS15870	COG1725	Transcriptional regulator
C9888_RS15880	COG1242	4 iron, 4 sulfur cluster binding
C9888_RS15885	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C9888_RS15895	COG0584	glycerophosphoryl diester phosphodiesterase
C9888_RS15905	COG2267	carboxylic ester hydrolase activity
C9888_RS15910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9888_RS15915	COG1113	amino acid transport
C9888_RS15920	COG0367	asparagine synthase
C9888_RS15940	COG1506	peptidase
C9888_RS15945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9888_RS15950	COG1116	anion transmembrane transporter activity
C9888_RS15955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9888_RS15960	COG0494	nUDIX hydrolase
C9888_RS15965	COG4824	toxin secretion phage lysis holin
C9888_RS15970	COG0783	Belongs to the Dps family
C9888_RS15995	COG0288	reversible hydration of carbon dioxide
C9888_RS16005	COG1271	oxidase subunit
C9888_RS16010	COG1294	oxidase, subunit
C9888_RS16020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9888_RS16025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9888_RS16025	COG1321	iron dependent repressor
C9888_RS16030	COG1121	(ABC) transporter
C9888_RS16035	COG0803	Belongs to the bacterial solute-binding protein 9 family
C9888_RS16040	COG4948	Mandelate Racemase Muconate Lactonizing
C9888_RS16050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9888_RS16055	COG0596	Alpha beta hydrolase
C9888_RS16065	COG1169	isochorismate synthase
C9888_RS16070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9888_RS16075	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C9888_RS16200	COG3859	Proton-coupled thiamine transporter YuaJ
C9888_RS16205	COG2268	Band 7 protein
C9888_RS16210	COG1585	Membrane protein implicated in regulation of membrane protease activity
C9888_RS16215	COG2318	DinB family
C9888_RS16225	COG1454	alcohol dehydrogenase
C9888_RS16230	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS16235	COG1510	regulation of RNA biosynthetic process
C9888_RS16245	COG0569	domain protein
C9888_RS16250	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9888_RS16255	COG1017	nitric oxide dioxygenase activity
C9888_RS16255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9888_RS16280	COG0628	permease
C9888_RS16285	COG0673	inositol 2-dehydrogenase activity
C9888_RS16290	COG0693	protein deglycase activity
C9888_RS16295	COG0840	transmembrane signaling receptor activity
C9888_RS16300	COG0840	transmembrane signaling receptor activity
C9888_RS16305	COG0840	transmembrane signaling receptor activity
C9888_RS16310	COG0840	transmembrane signaling receptor activity
C9888_RS16325	COG2070	2-Nitropropane dioxygenase
C9888_RS16330	COG0432	Pfam Uncharacterised protein family UPF0047
C9888_RS16335	COG0366	Alpha amylase catalytic
C9888_RS16340	COG1253	flavin adenine dinucleotide binding
C9888_RS16345	COG2738	Putative neutral zinc metallopeptidase
C9888_RS16360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9888_RS16390	COG1335	isochorismatase
C9888_RS16395	COG1979	alcohol dehydrogenase
C9888_RS16400	COG1979	alcohol dehydrogenase
C9888_RS16405	COG2155	Conserved Protein
C9888_RS16410	COG1098	S1 RNA binding domain
C9888_RS16415	COG0436	Aminotransferase
C9888_RS16420	COG1522	sequence-specific DNA binding
C9888_RS16425	COG2267	carboxylic ester hydrolase activity
C9888_RS16435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C9888_RS16440	COG2205	protein histidine kinase activity
C9888_RS16450	COG5018	Exonuclease
C9888_RS16455	COG2814	Major facilitator Superfamily
C9888_RS16460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9888_RS16465	COG3011	Protein conserved in bacteria
C9888_RS16475	COG3290	protein histidine kinase activity
C9888_RS16480	COG4565	transcriptional regulatory protein
C9888_RS16485	COG1744	ABC transporter substrate-binding protein PnrA-like
C9888_RS16490	COG3845	ABC transporter
C9888_RS16495	COG4603	Belongs to the binding-protein-dependent transport system permease family
C9888_RS16500	COG1079	Belongs to the binding-protein-dependent transport system permease family
C9888_RS16510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C9888_RS16510	COG2111	Na H antiporter
C9888_RS16515	COG2111	Na H antiporter
C9888_RS16520	COG1006	Multisubunit Na H antiporter MnhC subunit
C9888_RS16525	COG0651	ATP synthesis coupled electron transport
C9888_RS16530	COG1863	multisubunit Na H antiporter MnhE subunit
C9888_RS16535	COG2212	antiporter activity
C9888_RS16540	COG1320	monovalent cation:proton antiporter activity
C9888_RS16545	COG2050	protein possibly involved in aromatic compounds catabolism
C9888_RS16550	COG2197	response regulator
C9888_RS16555	COG4585	Histidine kinase
C9888_RS16565	COG0142	geranyltranstransferase activity
C9888_RS16585	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9888_RS16590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C9888_RS16595	COG1335	isochorismatase
C9888_RS16600	COG5506	Protein of unknown function (DUF1694)
C9888_RS16615	COG0628	permease
C9888_RS16625	COG1418	mRNA catabolic process
C9888_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS16640	COG1511	domain protein
C9888_RS16645	COG1674	ftsk spoiiie
C9888_RS16645	COG0433	COG0433 Predicted ATPase
C9888_RS16650	COG4499	WXG100 protein secretion system (Wss), protein YukC
C9888_RS16655	COG5417	Belongs to the EsaB family
C9888_RS16660	COG4842	Belongs to the WXG100 family
C9888_RS16665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C9888_RS16665	COG2508	Transcriptional regulator
C9888_RS16670	COG0686	Belongs to the AlaDH PNT family
C9888_RS16675	COG5634	Uncharacterized conserved protein (DUF2278)
C9888_RS16680	COG3251	PFAM MbtH domain protein
C9888_RS16685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS16690	COG3433	isochorismatase activity
C9888_RS16690	COG1535	isochorismatase
C9888_RS16695	COG1021	2,3-dihydroxybenzoate-AMP ligase
C9888_RS16700	COG1169	isochorismate synthase
C9888_RS16705	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS16710	COG2819	hydrolase of the alpha beta superfamily
C9888_RS16715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C9888_RS16720	COG1268	BioY protein
C9888_RS16725	COG2056	Na+-H+ antiporter family
C9888_RS16735	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C9888_RS16740	COG3584	3D domain protein
C9888_RS16755	COG1252	NADH dehydrogenase
C9888_RS16785	COG1131	(ABC) transporter
C9888_RS16805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9888_RS16810	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C9888_RS16830	COG0316	Belongs to the HesB IscA family
C9888_RS16840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9888_RS16850	COG1252	NADH dehydrogenase
C9888_RS16855	COG4837	Protein of unknown function (DUF1462)
C9888_RS16860	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C9888_RS16865	COG4946	Tricorn protease homolog
C9888_RS16865	COG1506	peptidase
C9888_RS16865	COG0823	Involved in the tonB-independent uptake of proteins
C9888_RS16875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9888_RS16880	COG0460	homoserine dehydrogenase
C9888_RS16885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9888_RS16890	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C9888_RS16895	COG0647	UMP catabolic process
C9888_RS16900	COG2445	Protein of unknown function DUF86
C9888_RS16905	COG4470	Protein conserved in bacteria
C9888_RS16920	COG0739	heme binding
C9888_RS16930	COG0737	Belongs to the 5'-nucleotidase family
C9888_RS16935	COG0730	response to heat
C9888_RS16940	COG1801	Protein of unknown function DUF72
C9888_RS16955	COG2508	Transcriptional regulator
C9888_RS16960	COG0457	Tetratricopeptide repeat
C9888_RS16975	COG2814	Major facilitator Superfamily
C9888_RS16980	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9888_RS16985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9888_RS16990	COG2356	endonuclease I
C9888_RS16995	COG3842	ATPase activity
C9888_RS17000	COG2188	Transcriptional regulator
C9888_RS17005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9888_RS17010	COG0395	ABC-type sugar transport system, permease component
C9888_RS17015	COG1175	transmembrane transport
C9888_RS17020	COG1653	transport
C9888_RS17025	COG2222	sugar isomerase
C9888_RS17030	COG0789	Transcriptional regulator
C9888_RS17055	COG0322	excinuclease ABC activity
C9888_RS17060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9888_RS17085	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS17090	COG0719	Fe-S assembly protein
C9888_RS17095	COG0822	iron-sulfur transferase activity
C9888_RS17100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9888_RS17105	COG0719	Fe-S assembly protein
C9888_RS17110	COG0396	ATPase activity
C9888_RS17120	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9888_RS17125	COG1464	Belongs to the NlpA lipoprotein family
C9888_RS17130	COG2011	ABC-type metal ion transport system permease component
C9888_RS17135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9888_RS17145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9888_RS17150	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C9888_RS17165	COG1393	Belongs to the ArsC family
C9888_RS17170	COG1960	acyl-CoA dehydrogenase activity
C9888_RS17175	COG0183	Belongs to the thiolase family
C9888_RS17180	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9888_RS17180	COG1024	Enoyl-CoA hydratase
C9888_RS17200	COG5577	PFAM Coat F domain
C9888_RS17205	COG1846	Transcriptional regulator
C9888_RS17210	COG0477	Major facilitator Superfamily
C9888_RS17215	COG0583	DNA-binding transcription factor activity
C9888_RS17235	COG1120	ATPase activity
C9888_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS17255	COG0783	Belongs to the Dps family
C9888_RS17260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9888_RS17265	COG0745	RESPONSE REGULATOR receiver
C9888_RS17270	COG2770	Histidine kinase
C9888_RS17270	COG2205	protein histidine kinase activity
C9888_RS17280	COG1309	transcriptional regulator
C9888_RS17285	COG0114	fumarate hydratase activity
C9888_RS17295	COG0697	spore germination
C9888_RS17300	COG0814	amino acid
C9888_RS17310	COG2197	response regulator
C9888_RS17315	COG4585	Histidine kinase
C9888_RS17320	COG4758	membrane
C9888_RS17325	COG3595	metallopeptidase activity
C9888_RS17330	COG1842	Phage shock protein A
C9888_RS17335	COG4758	membrane
C9888_RS17340	COG2814	Major facilitator Superfamily
C9888_RS17345	COG2096	Adenosyltransferase
C9888_RS17350	COG1120	ATPase activity
C9888_RS17355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS17360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9888_RS17365	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS17370	COG3386	PFAM SMP-30 Gluconolaconase
C9888_RS17375	COG2205	protein histidine kinase activity
C9888_RS17380	COG0745	RESPONSE REGULATOR receiver
C9888_RS17390	COG1191	sigma factor activity
C9888_RS17400	COG2140	Oxalate decarboxylase
C9888_RS17410	COG1120	ATPase activity
C9888_RS17415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS17420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS17425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9888_RS17430	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C9888_RS17435	COG0531	amino acid
C9888_RS17450	COG1988	membrane-bound metal-dependent
C9888_RS17455	COG1368	sulfuric ester hydrolase activity
C9888_RS17460	COG1910	domain protein
C9888_RS17465	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9888_RS17470	COG4149	molybdate abc transporter
C9888_RS17475	COG2197	response regulator
C9888_RS17480	COG3850	Histidine kinase
C9888_RS17485	COG1131	(ABC) transporter
C9888_RS17495	COG0842	Transport permease protein
C9888_RS17500	COG0656	L-ascorbic acid biosynthetic process
C9888_RS17525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9888_RS17530	COG3973	AAA domain
C9888_RS17535	COG2860	membrane
C9888_RS17545	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9888_RS17550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9888_RS17555	COG2217	Heavy metal translocating P-type atpase
C9888_RS17560	COG2217	Heavy metal translocating P-type atpase
C9888_RS17565	COG2608	mercury ion transmembrane transporter activity
C9888_RS17570	COG1937	Protein conserved in bacteria
C9888_RS17575	COG0673	inositol 2-dehydrogenase activity
C9888_RS17585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS17590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9888_RS17595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS17600	COG1126	abc transporter atp-binding protein
C9888_RS17605	COG0765	amino acid transport
C9888_RS17610	COG0765	amino acid transport
C9888_RS17615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS17620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9888_RS17625	COG0454	-acetyltransferase
C9888_RS17630	COG0583	DNA-binding transcription factor activity
C9888_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS17640	COG2732	(Barnase) inhibitor
C9888_RS17650	COG2732	(Barnase) inhibitor
C9888_RS17665	COG0557	exoribonuclease II activity
C9888_RS17670	COG1647	Serine aminopeptidase, S33
C9888_RS17675	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9888_RS17680	COG1476	TRANSCRIPTIONal
C9888_RS17685	COG1396	sequence-specific DNA binding
C9888_RS17690	COG1396	sequence-specific DNA binding
C9888_RS17695	COG1733	regulation of RNA biosynthetic process
C9888_RS17720	COG1131	(ABC) transporter
C9888_RS17725	COG1174	glycine betaine transport
C9888_RS17730	COG1732	Glycine betaine
C9888_RS17735	COG1174	glycine betaine transport
C9888_RS17740	COG1125	glycine betaine transport
C9888_RS17740	COG0517	IMP dehydrogenase activity
C9888_RS17745	COG1510	regulation of RNA biosynthetic process
C9888_RS17750	COG1174	glycine betaine transport
C9888_RS17755	COG1732	Glycine betaine
C9888_RS17760	COG1174	glycine betaine transport
C9888_RS17765	COG1125	glycine betaine transport
C9888_RS17765	COG0517	IMP dehydrogenase activity
C9888_RS17770	COG1510	regulation of RNA biosynthetic process
C9888_RS17775	COG2095	MarC family integral membrane protein
C9888_RS17785	COG3064	Membrane
C9888_RS17790	COG4640	response to antibiotic
C9888_RS17795	COG0456	acetyltransferase
C9888_RS17815	COG0126	phosphoglycerate kinase activity
C9888_RS17825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9888_RS17830	COG2390	Transcriptional regulator
C9888_RS17835	COG2814	Major facilitator Superfamily
C9888_RS17840	COG1609	Transcriptional regulator
C9888_RS17845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS17850	COG0583	DNA-binding transcription factor activity
C9888_RS17855	COG0697	spore germination
C9888_RS17860	COG1113	amino acid transport
C9888_RS17865	COG1737	Transcriptional regulator
C9888_RS17870	COG1070	Carbohydrate kinase
C9888_RS17905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS17910	COG2186	Transcriptional regulator
C9888_RS17915	COG1620	l-lactate permease
C9888_RS17920	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C9888_RS17930	COG5039	Polysaccharide pyruvyl transferase
C9888_RS17935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9888_RS17940	COG0110	maltose O-acetyltransferase activity
C9888_RS17945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9888_RS17950	COG2244	polysaccharide biosynthetic process
C9888_RS17955	COG1216	Glycosyl transferase, family 2
C9888_RS17960	COG5039	Polysaccharide pyruvyl transferase
C9888_RS17965	COG1216	Glycosyl transferase, family 2
C9888_RS17975	COG0438	transferase activity, transferring glycosyl groups
C9888_RS17980	COG1215	transferase activity, transferring glycosyl groups
C9888_RS17985	COG0438	transferase activity, transferring glycosyl groups
C9888_RS17990	COG1086	Polysaccharide biosynthesis protein
C9888_RS17995	COG0489	protein tyrosine kinase activity
C9888_RS18000	COG3944	biosynthesis protein
C9888_RS18005	COG1396	sequence-specific DNA binding
C9888_RS18010	COG2272	Belongs to the type-B carboxylesterase lipase family
C9888_RS18020	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9888_RS18025	COG2364	Membrane
C9888_RS18030	COG0456	acetyltransferase
C9888_RS18035	COG3479	Phenolic acid decarboxylase
C9888_RS18090	COG2223	nitrite transmembrane transporter activity
C9888_RS18095	COG1609	Transcriptional regulator
C9888_RS18105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9888_RS18110	COG0366	Alpha amylase catalytic
C9888_RS18115	COG1554	hydrolase, family 65, central catalytic
C9888_RS18120	COG5521	maltodextrose utilization protein MalA
C9888_RS18125	COG3833	ABC-type maltose transport systems, permease component
C9888_RS18130	COG1175	transmembrane transport
C9888_RS18135	COG2182	Extracellular solute-binding protein
C9888_RS18145	COG1609	Transcriptional regulator
C9888_RS18150	COG1611	Belongs to the LOG family
C9888_RS18155	COG1694	Mazg nucleotide pyrophosphohydrolase
C9888_RS18160	COG0659	secondary active sulfate transmembrane transporter activity
C9888_RS18165	COG0288	reversible hydration of carbon dioxide
C9888_RS18175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9888_RS18180	COG4290	ribonuclease
C9888_RS18185	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C9888_RS18190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS18200	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9888_RS18210	COG1051	belongs to the nudix hydrolase family
C9888_RS18215	COG0492	ferredoxin-NADP+ reductase activity
C9888_RS18220	COG3883	PFAM NLP P60 protein
C9888_RS18220	COG0791	NLP P60 protein
C9888_RS18225	COG0457	Tetratricopeptide repeat
C9888_RS18230	COG5002	protein histidine kinase activity
C9888_RS18235	COG0745	RESPONSE REGULATOR receiver
C9888_RS18245	COG1132	(ABC) transporter
C9888_RS18250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C9888_RS18250	COG0140	phosphoribosyl-ATP diphosphatase activity
C9888_RS18275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9888_RS18290	COG4990	cell redox homeostasis
C9888_RS18295	COG0110	maltose O-acetyltransferase activity
C9888_RS18315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9888_RS18325	COG2188	Transcriptional regulator
C9888_RS18330	COG1309	transcriptional regulator
C9888_RS18335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C9888_RS18340	COG1950	PFAM Membrane protein of
C9888_RS18345	COG1983	PspC domain protein
C9888_RS18350	COG3595	metallopeptidase activity
C9888_RS18365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9888_RS18375	COG4897	Protein conserved in bacteria
C9888_RS18380	COG0574	Belongs to the PEP-utilizing enzyme family
C9888_RS18380	COG3848	Pyruvate phosphate dikinase
C9888_RS18385	COG1309	transcriptional regulator
C9888_RS18390	COG2814	Major facilitator Superfamily
C9888_RS18415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C9888_RS18430	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS18445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9888_RS18455	COG0793	Belongs to the peptidase S41A family
C9888_RS18455	COG3409	Peptidoglycan-binding domain 1 protein
C9888_RS18460	COG3420	alginic acid biosynthetic process
C9888_RS18465	COG2177	Part of the ABC transporter FtsEX involved in
C9888_RS18470	COG2884	Cell division ATP-binding protein ftsE
C9888_RS18475	COG2010	Cytochrome c
C9888_RS18480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS18495	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9888_RS18510	COG1516	flagellar protein fliS
C9888_RS18515	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9888_RS18520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9888_RS18540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9888_RS18545	COG4786	Flagellar basal body rod
C9888_RS18545	COG1256	bacterial-type flagellum assembly
C9888_RS18550	COG3418	PFAM FlgN family protein
C9888_RS18555	COG2747	anti-sigma28 factor FlgM
C9888_RS18565	COG1040	competence protein
C9888_RS18575	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C9888_RS18580	COG1307	EDD domain protein, DegV family
C9888_RS18585	COG2197	response regulator
C9888_RS18590	COG4585	Histidine kinase
C9888_RS18595	COG1739	Uncharacterized protein family UPF0029
C9888_RS18600	COG1316	TRANSCRIPTIONal
C9888_RS18605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9888_RS18610	COG0438	transferase activity, transferring glycosyl groups
C9888_RS18615	COG1215	transferase activity, transferring glycosyl groups
C9888_RS18620	COG3206	protein involved in exopolysaccharide biosynthesis
C9888_RS18625	COG3307	-O-antigen
C9888_RS18630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9888_RS18635	COG0438	transferase activity, transferring glycosyl groups
C9888_RS18635	COG0297	glycogen (starch) synthase activity
C9888_RS18640	COG2244	polysaccharide biosynthetic process
C9888_RS18650	COG0860	N-Acetylmuramoyl-L-alanine amidase
C9888_RS18650	COG2247	cell wall binding repeat
C9888_RS18655	COG2247	cell wall binding repeat
C9888_RS18655	COG2385	sporulation resulting in formation of a cellular spore
C9888_RS18665	COG1316	TRANSCRIPTIONal
C9888_RS18670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C9888_RS18675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C9888_RS18680	COG1134	teichoic acid transport
C9888_RS18685	COG1682	transport, permease protein
C9888_RS18690	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9888_RS18700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C9888_RS18705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C9888_RS18710	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9888_RS18715	COG4193	domain, Protein
C9888_RS18720	COG1482	cell wall glycoprotein biosynthetic process
C9888_RS18725	COG0697	spore germination
C9888_RS18730	COG0814	amino acid
C9888_RS18740	COG1215	transferase activity, transferring glycosyl groups
C9888_RS18745	COG2814	Major facilitator Superfamily
C9888_RS18750	COG1316	TRANSCRIPTIONal
C9888_RS18755	COG0561	phosphatase activity
C9888_RS18760	COG2433	Pfam Transposase IS66
C9888_RS18765	COG0791	NLP P60 protein
C9888_RS18775	COG2843	Capsule synthesis protein
C9888_RS18785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9888_RS18795	COG0697	spore germination
C9888_RS18800	COG0814	amino acid
C9888_RS18810	COG1609	Transcriptional regulator
C9888_RS18815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9888_RS18825	COG1129	ABC transporter
C9888_RS18830	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9888_RS18835	COG1879	ABC-type sugar transport system periplasmic component
C9888_RS18840	COG3103	Sh3 type 3 domain protein
C9888_RS18845	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9888_RS18850	COG3527	Alpha-acetolactate decarboxylase
C9888_RS18855	COG0028	Belongs to the TPP enzyme family
C9888_RS18860	COG0583	DNA-binding transcription factor activity
C9888_RS18865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9888_RS18880	COG5337	Spore coat protein CotH
C9888_RS18890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C9888_RS18900	COG0405	Gamma-glutamyltransferase
C9888_RS18905	COG1522	sequence-specific DNA binding
C9888_RS18910	COG2059	Chromate
C9888_RS18915	COG2059	Chromate
C9888_RS18925	COG0655	NAD(P)H dehydrogenase (quinone) activity
C9888_RS18930	COG0583	DNA-binding transcription factor activity
C9888_RS18965	COG5444	nuclease activity
C9888_RS18980	COG3878	Protein conserved in bacteria
C9888_RS18985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C9888_RS18990	COG4464	protein tyrosine phosphatase activity
C9888_RS18995	COG0489	protein tyrosine kinase activity
C9888_RS19000	COG3944	biosynthesis protein
C9888_RS19015	COG4715	Zinc finger, swim domain protein
C9888_RS19020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9888_RS19025	COG0561	phosphatase activity
C9888_RS19030	COG1349	DNA-binding transcription factor activity
C9888_RS19035	COG0629	single-stranded DNA binding
C9888_RS19060	COG0457	Tetratricopeptide repeat
C9888_RS19065	COG4786	Flagellar basal body rod
C9888_RS19070	COG4786	Flagellar basal body rod
C9888_RS19075	COG1077	Cell shape determining protein MreB Mrl
C9888_RS19080	COG1609	Transcriptional regulator
C9888_RS19090	COG2814	Major facilitator Superfamily
C9888_RS19095	COG1953	Uracil, thiamine, allantoin
C9888_RS19100	COG0477	Major facilitator Superfamily
C9888_RS19105	COG1335	isochorismatase
C9888_RS19110	COG0004	ammonium transporteR
C9888_RS19115	COG0347	Belongs to the P(II) protein family
C9888_RS19120	COG0772	Belongs to the SEDS family
C9888_RS19125	COG0671	phosphoesterase, PA-phosphatase related
C9888_RS19135	COG0739	heme binding
C9888_RS19140	COG1247	-acetyltransferase
C9888_RS19155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9888_RS19165	COG0726	polysaccharide deacetylase
C9888_RS19175	COG1959	2 iron, 2 sulfur cluster binding
C9888_RS19190	COG0831	urea catabolic process
C9888_RS19200	COG1994	Peptidase M50
C9888_RS19205	COG0457	Tetratricopeptide repeat
C9888_RS19215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9888_RS19220	COG2304	oxidoreductase activity
C9888_RS19225	COG2304	oxidoreductase activity
C9888_RS19230	COG2385	sporulation resulting in formation of a cellular spore
C9888_RS19235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9888_RS19245	COG4836	Membrane
C9888_RS19315	COG0698	ribose 5-phosphate isomerase
C9888_RS19320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9888_RS19330	COG0009	L-threonylcarbamoyladenylate synthase
C9888_RS19335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9888_RS19355	COG2890	protein-(glutamine-N5) methyltransferase activity
C9888_RS19360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9888_RS19365	COG0346	lactoylglutathione lyase activity
C9888_RS19370	COG0789	Transcriptional regulator
C9888_RS19375	COG0679	Auxin Efflux Carrier
C9888_RS19380	COG0281	malic enzyme
C9888_RS19395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9888_RS19400	COG1494	fructose-1,6-bisphosphatase
C9888_RS19405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9888_RS19415	COG0191	fructose-bisphosphate aldolase activity
C9888_RS19420	COG2204	response regulator
C9888_RS19425	COG4821	SIS domain
C9888_RS19440	COG0247	lactate metabolic process
C9888_RS19440	COG2181	nitrate reductase activity
C9888_RS19445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9888_RS19460	COG1132	(ABC) transporter
C9888_RS19465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9888_RS19475	COG2181	nitrate reductase activity
C9888_RS19480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C9888_RS19485	COG1140	nitrate reductase beta subunit
C9888_RS19490	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C9888_RS19495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9888_RS19505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9888_RS19510	COG2223	nitrite transmembrane transporter activity
C9888_RS19520	COG4506	Protein conserved in bacteria
C9888_RS19525	COG0457	Tetratricopeptide repeat
C9888_RS19570	COG0010	Belongs to the arginase family
C9888_RS19575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C9888_RS19580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9888_RS19595	COG1994	Peptidase M50
C9888_RS19600	COG1942	4-Oxalocrotonate Tautomerase
C9888_RS19605	COG1846	Transcriptional regulator
C9888_RS19615	COG0531	amino acid
C9888_RS19620	COG3465	dGTPase activity
C9888_RS19625	COG1078	dGTPase activity
C9888_RS19640	COG1695	Transcriptional regulator
C9888_RS19650	COG1131	(ABC) transporter
C9888_RS19655	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C9888_RS19685	COG0583	DNA-binding transcription factor activity
C9888_RS19690	COG2855	membrane
C9888_RS19695	COG0280	phosphate acetyltransferase
C9888_RS19705	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS19710	COG0436	Aminotransferase
C9888_RS19740	COG2814	Major facilitator Superfamily
C9888_RS19745	COG2814	Major facilitator Superfamily
C9888_RS19750	COG0833	amino acid
C9888_RS19755	COG4187	Peptidase family M20/M25/M40
C9888_RS19760	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS19765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C9888_RS19770	COG2205	protein histidine kinase activity
C9888_RS19775	COG0745	RESPONSE REGULATOR receiver
C9888_RS19790	COG1131	(ABC) transporter
C9888_RS19795	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
C9888_RS19800	COG1091	dTDP-4-dehydrorhamnose reductase activity
C9888_RS19805	COG1088	dTDP-glucose 4,6-dehydratase activity
C9888_RS19810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C9888_RS19815	COG3980	spore coat polysaccharide biosynthesis protein
C9888_RS19820	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C9888_RS19825	COG2089	acid synthase
C9888_RS19830	COG0456	acetyltransferase
C9888_RS19835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C9888_RS19840	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C9888_RS19845	COG0463	Glycosyl transferase, family 2
C9888_RS19855	COG2363	Small membrane protein
C9888_RS19860	COG2233	PERMEase
C9888_RS19875	COG1216	Glycosyl transferase, family 2
C9888_RS19890	COG1695	Transcriptional regulator
C9888_RS19895	COG0351	phosphomethylpyrimidine kinase
C9888_RS19905	COG1621	beta-fructofuranosidase activity
C9888_RS19910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9888_RS19910	COG1263	PTS System
C9888_RS19915	COG3711	transcriptional antiterminator
C9888_RS19925	COG1404	Belongs to the peptidase S8 family
C9888_RS19930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C9888_RS19935	COG0778	Nitroreductase
C9888_RS19940	COG0772	Belongs to the SEDS family
C9888_RS19945	COG0454	-acetyltransferase
C9888_RS19965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9888_RS19970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9888_RS19975	COG2261	transglycosylase associated protein
C9888_RS19980	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C9888_RS19985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9888_RS19990	COG2246	polysaccharide biosynthetic process
C9888_RS19995	COG1309	transcriptional regulator
C9888_RS20015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C9888_RS20020	COG2837	iron assimilation
C9888_RS20025	COG2822	iron ion transport
C9888_RS20040	COG0583	DNA-binding transcription factor activity
C9888_RS20050	COG1346	cytolysis
C9888_RS20055	COG4895	conserved protein (DUF2196)
C9888_RS20060	COG0789	Transcriptional regulator
C9888_RS20070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C9888_RS20075	COG0346	lactoylglutathione lyase activity
C9888_RS20080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS20085	COG1404	Belongs to the peptidase S8 family
C9888_RS20090	COG1442	glycosyl transferase family 8
C9888_RS20095	COG1846	Transcriptional regulator
C9888_RS20100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9888_RS20105	COG2357	RelA SpoT domain protein
C9888_RS20110	COG1575	Belongs to the MenA family. Type 1 subfamily
C9888_RS20130	COG1696	Membrane protein involved in D-alanine export
C9888_RS20140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C9888_RS20145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9888_RS20150	COG1486	melibiose metabolic process
C9888_RS20155	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9888_RS20160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS20165	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS20170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9888_RS20170	COG3711	transcriptional antiterminator
C9888_RS20185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS20190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9888_RS20200	COG0640	Transcriptional regulator
C9888_RS20205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C9888_RS20210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS20215	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9888_RS20220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9888_RS20225	COG2723	6-phospho-beta-galactosidase activity
C9888_RS20230	COG1940	carbohydrate kinase activity
C9888_RS20235	COG1482	cell wall glycoprotein biosynthetic process
C9888_RS20245	COG0753	catalase activity
C9888_RS20250	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C9888_RS20255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9888_RS20260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9888_RS20265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C9888_RS20270	COG4988	ABC transporter
C9888_RS20275	COG1294	oxidase, subunit
C9888_RS20280	COG1271	oxidase subunit
C9888_RS20285	COG3493	citrate carrier protein
C9888_RS20290	COG0726	polysaccharide deacetylase
C9888_RS20295	COG3842	ATPase activity
C9888_RS20300	COG2508	Transcriptional regulator
C9888_RS20305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS20315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9888_RS20325	COG4894	glucomannan catabolic process
C9888_RS20330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9888_RS20335	COG0500	methyltransferase
C9888_RS20340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9888_RS20360	COG0693	protein deglycase activity
C9888_RS20360	COG0753	catalase activity
C9888_RS20365	COG2851	Citrate transporter
C9888_RS20370	COG2273	Hydrolase Family 16
C9888_RS20375	COG3711	transcriptional antiterminator
C9888_RS20380	COG2270	Major facilitator Superfamily
C9888_RS20385	COG0513	Belongs to the DEAD box helicase family
C9888_RS20435	COG3209	COG3209 Rhs family protein
C9888_RS20445	COG0697	spore germination
C9888_RS20450	COG0589	response to stress
C9888_RS20460	COG0494	nUDIX hydrolase
C9888_RS20465	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9888_RS20470	COG3507	Belongs to the glycosyl hydrolase 43 family
C9888_RS20495	COG0010	Belongs to the arginase family
C9888_RS20500	COG0833	amino acid
C9888_RS20505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C9888_RS20510	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9888_RS20520	COG2390	Transcriptional regulator
C9888_RS20525	COG0561	phosphatase activity
C9888_RS20555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9888_RS20560	COG5294	Protein conserved in bacteria
C9888_RS20565	COG0577	efflux transmembrane transporter activity
C9888_RS20570	COG1136	(ABC) transporter
C9888_RS20575	COG2205	protein histidine kinase activity
C9888_RS20580	COG0745	RESPONSE REGULATOR receiver
C9888_RS20585	COG2205	protein histidine kinase activity
C9888_RS20590	COG0745	RESPONSE REGULATOR receiver
C9888_RS20615	COG0745	RESPONSE REGULATOR receiver
C9888_RS20645	COG1082	Xylose isomerase domain protein TIM barrel
C9888_RS20655	COG2814	Major facilitator Superfamily
C9888_RS20685	COG1349	DNA-binding transcription factor activity
C9888_RS20690	COG0667	Aldo Keto reductase
C9888_RS20695	COG2814	Major facilitator Superfamily
C9888_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
C9888_RS20715	COG2197	response regulator
C9888_RS20720	COG4585	Histidine kinase
C9888_RS20725	COG3239	Fatty acid desaturase
C9888_RS20735	COG1309	transcriptional regulator
C9888_RS20740	COG1012	belongs to the aldehyde dehydrogenase family
C9888_RS20745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9888_RS20755	COG0640	Transcriptional regulator
C9888_RS20765	COG1714	RDD family
C9888_RS20775	COG0450	alkyl hydroperoxide reductase
C9888_RS20780	COG3634	alkyl hydroperoxide reductase activity
C9888_RS20785	COG3177	Filamentation induced by cAMP protein fic
C9888_RS20790	COG1113	amino acid transport
C9888_RS20800	COG2080	2 iron, 2 sulfur cluster binding
C9888_RS20815	COG2068	MobA-Related Protein
C9888_RS20820	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C9888_RS20885	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
C9888_RS20890	COG0667	Aldo Keto reductase
C9888_RS20895	COG0456	acetyltransferase
C9888_RS20900	COG0457	Tetratricopeptide repeat
C9888_RS20905	COG0010	Belongs to the arginase family
C9888_RS20910	COG0833	amino acid
C9888_RS20915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9888_RS20920	COG3829	transcription factor binding
C9888_RS20930	COG0488	(ABC) transporter
C9888_RS20945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9888_RS20950	COG5002	protein histidine kinase activity
C9888_RS20950	COG3850	Histidine kinase
C9888_RS20955	COG0745	RESPONSE REGULATOR receiver
C9888_RS20965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9888_RS20970	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C9888_RS20975	COG4853	Protein conserved in bacteria
C9888_RS20980	COG4863	YycH protein
C9888_RS20985	COG5002	protein histidine kinase activity
C9888_RS20990	COG0745	RESPONSE REGULATOR receiver
C9888_RS21025	COG0346	lactoylglutathione lyase activity
C9888_RS21030	COG0305	Participates in initiation and elongation during chromosome replication
C9888_RS21045	COG3093	addiction module antidote protein HigA
C9888_RS21050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C9888_RS21055	COG0297	glycogen (starch) synthase activity
C9888_RS21065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C9888_RS21070	COG0438	transferase activity, transferring glycosyl groups
C9888_RS21080	COG2112	serine threonine protein kinase
C9888_RS21090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C9888_RS21095	COG4241	membrane
C9888_RS21105	COG5577	PFAM Coat F domain
C9888_RS21110	COG1733	regulation of RNA biosynthetic process
C9888_RS21120	COG0697	spore germination
C9888_RS21125	COG1621	beta-fructofuranosidase activity
C9888_RS21130	COG1621	beta-fructofuranosidase activity
C9888_RS21135	COG1802	Transcriptional regulator
C9888_RS21145	COG2211	Major facilitator Superfamily
C9888_RS21150	COG0697	spore germination
C9888_RS21160	COG0778	Nitroreductase
C9888_RS21165	COG1846	Transcriptional regulator
C9888_RS21170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9888_RS21175	COG1846	Transcriptional regulator
C9888_RS21180	COG2153	protein acetylation
C9888_RS21190	COG0546	phosphoglycolate phosphatase activity
C9888_RS21220	COG1404	Belongs to the peptidase S8 family
C9888_RS21230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9888_RS21235	COG0697	spore germination
C9888_RS21240	COG1331	Highly conserved protein containing a thioredoxin domain
C9888_RS21245	COG1266	CAAX protease self-immunity
C9888_RS21250	COG0477	Major facilitator Superfamily
C9888_RS21250	COG2814	Major facilitator Superfamily
C9888_RS21255	COG0346	lactoylglutathione lyase activity
C9888_RS21260	COG1609	Transcriptional regulator
C9888_RS21270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9888_RS21275	COG2169	Transcriptional regulator
C9888_RS21285	COG0629	single-stranded DNA binding
C9888_RS21295	COG0012	GTP binding
C9888_RS21300	COG0243	molybdopterin cofactor binding
C9888_RS21305	COG4481	Protein conserved in bacteria
C9888_RS21310	COG3949	Membrane
C9888_RS21325	COG1475	DNA binding
C9888_RS21330	COG1192	Involved in chromosome partitioning
C9888_RS21355	COG1847	R3H domain protein
C9888_RS21360	COG0706	membrane insertase activity