locus-tag	class	description
HUW56_RS00005	COG0444	Belongs to the ABC transporter superfamily
HUW56_RS00010	COG4166	transmembrane transport
HUW56_RS00015	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUW56_RS00020	COG4948	Mandelate Racemase Muconate Lactonizing
HUW56_RS00025	COG0791	NLP P60 protein
HUW56_RS00030	COG4608	Belongs to the ABC transporter superfamily
HUW56_RS00035	COG2706	6-phosphogluconolactonase activity
HUW56_RS00040	COG1834	amidinotransferase
HUW56_RS00045	COG1607	acyl-coa hydrolase
HUW56_RS00050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUW56_RS00055	COG2076	Multidrug Resistance protein
HUW56_RS00060	COG2076	Multidrug Resistance protein
HUW56_RS00065	COG0788	formyltetrahydrofolate deformylase activity
HUW56_RS00070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUW56_RS00080	COG1764	response to oxidative stress
HUW56_RS00085	COG1846	Transcriptional regulator
HUW56_RS00090	COG1764	response to oxidative stress
HUW56_RS00105	COG0457	Tetratricopeptide repeat
HUW56_RS00105	COG0463	Glycosyl transferase, family 2
HUW56_RS00125	COG1404	Belongs to the peptidase S8 family
HUW56_RS00130	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS00135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUW56_RS00140	COG1122	ATPase activity
HUW56_RS00145	COG4721	ABC-type cobalt transport system, permease component
HUW56_RS00150	COG3858	chitin binding
HUW56_RS00150	COG1388	LysM domain
HUW56_RS00160	COG2239	Acts as a magnesium transporter
HUW56_RS00165	COG0789	Transcriptional regulator
HUW56_RS00180	COG1846	Transcriptional regulator
HUW56_RS00185	COG0726	polysaccharide deacetylase
HUW56_RS00190	COG3285	dna ligase
HUW56_RS00190	COG1793	dna ligase
HUW56_RS00195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUW56_RS00200	COG0586	Pfam SNARE associated Golgi protein
HUW56_RS00205	COG0861	Integral membrane protein TerC family
HUW56_RS00210	COG1191	sigma factor activity
HUW56_RS00235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HUW56_RS00240	COG2323	membrane
HUW56_RS00250	COG3594	Acyltransferase
HUW56_RS00255	COG5002	protein histidine kinase activity
HUW56_RS00260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUW56_RS00275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUW56_RS00280	COG0436	Aminotransferase
HUW56_RS00310	COG3852	Histidine kinase
HUW56_RS00315	COG1846	Transcriptional regulator
HUW56_RS00320	COG1360	Flagellar Motor Protein
HUW56_RS00325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUW56_RS00330	COG0542	response to heat
HUW56_RS00335	COG3949	Membrane
HUW56_RS00350	COG0720	synthase
HUW56_RS00355	COG0602	queuosine metabolic process
HUW56_RS00370	COG1733	regulation of RNA biosynthetic process
HUW56_RS00375	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS00390	COG4873	Protein conserved in bacteria
HUW56_RS00400	COG3773	Cell wall hydrolase
HUW56_RS00405	COG2244	polysaccharide biosynthetic process
HUW56_RS00410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS00415	COG2217	Heavy metal translocating P-type atpase
HUW56_RS00420	COG0006	proline dipeptidase activity
HUW56_RS00425	COG1609	Transcriptional regulator
HUW56_RS00430	COG3711	transcriptional antiterminator
HUW56_RS00435	COG1263	PTS System
HUW56_RS00435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS00435	COG2190	(PTS) system
HUW56_RS00440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS00445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUW56_RS00455	COG1533	DNA photolyase activity
HUW56_RS00460	COG0840	transmembrane signaling receptor activity
HUW56_RS00465	COG2084	Dehydrogenase
HUW56_RS00470	COG2340	Cysteine-rich secretory protein family
HUW56_RS00475	COG0768	penicillin binding
HUW56_RS00480	COG4191	Histidine kinase
HUW56_RS00485	COG0436	Aminotransferase
HUW56_RS00495	COG0835	chemotaxis
HUW56_RS00495	COG0784	Response regulator, receiver
HUW56_RS00505	COG2814	Major facilitator Superfamily
HUW56_RS00510	COG1376	ErfK ybiS ycfS ynhG family protein
HUW56_RS00515	COG1408	metallophosphoesterase
HUW56_RS00520	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS00530	COG2200	EAL domain
HUW56_RS00535	COG4703	Protein of unknown function (DUF1797)
HUW56_RS00540	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HUW56_RS00550	COG0517	IMP dehydrogenase activity
HUW56_RS00555	COG0583	DNA-binding transcription factor activity
HUW56_RS00560	COG0716	FMN binding
HUW56_RS00570	COG0716	FMN binding
HUW56_RS00590	COG0668	transmembrane transport
HUW56_RS00595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS00615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUW56_RS00620	COG0303	'Molybdopterin
HUW56_RS00625	COG1763	Mo-molybdopterin cofactor biosynthetic process
HUW56_RS00630	COG0314	molybdopterin synthase activity
HUW56_RS00635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HUW56_RS00645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUW56_RS00650	COG1136	(ABC) transporter
HUW56_RS00655	COG0577	efflux transmembrane transporter activity
HUW56_RS00660	COG1349	DNA-binding transcription factor activity
HUW56_RS00665	COG1105	Belongs to the carbohydrate kinase PfkB family
HUW56_RS00670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUW56_RS00670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUW56_RS00670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS00675	COG0681	Belongs to the peptidase S26 family
HUW56_RS00685	COG0488	(ABC) transporter
HUW56_RS00690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUW56_RS00695	COG2309	aminopeptidase activity
HUW56_RS00705	COG1077	Cell shape determining protein MreB Mrl
HUW56_RS00710	COG2002	toxin-antitoxin pair type II binding
HUW56_RS00715	COG3852	Histidine kinase
HUW56_RS00720	COG2105	PFAM AIG2 family protein
HUW56_RS00720	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HUW56_RS00725	COG0569	domain protein
HUW56_RS00735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUW56_RS00745	COG0561	phosphatase activity
HUW56_RS00750	COG0242	peptide deformylase activity
HUW56_RS00760	COG0497	DNA recombination
HUW56_RS00765	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUW56_RS00765	COG2070	2-Nitropropane dioxygenase
HUW56_RS00770	COG3321	synthase
HUW56_RS00770	COG4221	oxidoreductase activity
HUW56_RS00770	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS00770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS00775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS00775	COG0300	oxidoreductase activity
HUW56_RS00775	COG3321	synthase
HUW56_RS00775	COG4221	oxidoreductase activity
HUW56_RS00780	COG4221	oxidoreductase activity
HUW56_RS00780	COG3321	synthase
HUW56_RS00780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS00785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS00785	COG3321	synthase
HUW56_RS00785	COG4221	oxidoreductase activity
HUW56_RS00785	COG0300	oxidoreductase activity
HUW56_RS00790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS00790	COG0300	oxidoreductase activity
HUW56_RS00790	COG3321	synthase
HUW56_RS00790	COG4221	oxidoreductase activity
HUW56_RS00795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS00795	COG0300	oxidoreductase activity
HUW56_RS00795	COG4221	oxidoreductase activity
HUW56_RS00795	COG3321	synthase
HUW56_RS00800	COG3321	synthase
HUW56_RS00800	COG4221	oxidoreductase activity
HUW56_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS00800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS00805	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUW56_RS00810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUW56_RS00815	COG0022	dehydrogenase e1 component
HUW56_RS00820	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUW56_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUW56_RS00830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS00845	COG1982	Orn Lys Arg decarboxylase major
HUW56_RS00865	COG0483	inositol monophosphate 1-phosphatase activity
HUW56_RS00875	COG3227	Zinc metalloprotease (Elastase)
HUW56_RS00910	COG4896	Protein conserved in bacteria
HUW56_RS00920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUW56_RS00925	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUW56_RS00930	COG2066	Belongs to the glutaminase family
HUW56_RS00940	COG0772	Belongs to the SEDS family
HUW56_RS00945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HUW56_RS00960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUW56_RS00960	COG2010	Cytochrome c
HUW56_RS00965	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUW56_RS00970	COG1845	cytochrome c oxidase, subunit III
HUW56_RS00975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HUW56_RS00980	COG3336	cytochrome c oxidase
HUW56_RS00990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HUW56_RS00995	COG2340	Cysteine-rich secretory protein family
HUW56_RS01010	COG3679	Belongs to the UPF0342 family
HUW56_RS01020	COG0742	ribosomal rna small subunit methyltransferase
HUW56_RS01030	COG3314	Sporulation integral membrane protein YlbJ
HUW56_RS01035	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUW56_RS01040	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUW56_RS01050	COG1399	metal-binding, possibly nucleic acid-binding protein
HUW56_RS01070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUW56_RS01090	COG4839	cell division protein FtsL
HUW56_RS01100	COG0768	penicillin binding
HUW56_RS01120	COG0772	Belongs to the SEDS family
HUW56_RS01135	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUW56_RS01140	COG0849	cell division
HUW56_RS01145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUW56_RS01150	COG4412	M6 family metalloprotease domain protein
HUW56_RS01150	COG1404	Belongs to the peptidase S8 family
HUW56_RS01160	COG1191	sigma factor activity
HUW56_RS01165	COG1191	sigma factor activity
HUW56_RS01170	COG1119	ATPase activity
HUW56_RS01175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUW56_RS01180	COG1873	PFAM PRC-barrel domain
HUW56_RS01190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUW56_RS01200	COG0762	integral membrane protein
HUW56_RS01205	COG2302	S4 RNA-binding domain
HUW56_RS01210	COG3599	regulation of cell shape
HUW56_RS01215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUW56_RS01220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUW56_RS01230	COG0564	pseudouridine synthase activity
HUW56_RS01240	COG2233	PERMEase
HUW56_RS01250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUW56_RS01255	COG0505	Belongs to the CarA family
HUW56_RS01260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUW56_RS01275	COG0284	orotidine-5'-phosphate decarboxylase activity
HUW56_RS01280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HUW56_RS01290	COG0306	phosphate transporter
HUW56_RS01305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUW56_RS01310	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HUW56_RS01315	COG1648	precorrin-2 dehydrogenase activity
HUW56_RS01325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUW56_RS01330	COG1561	YicC-like family, N-terminal region
HUW56_RS01340	COG0194	GDP metabolic process
HUW56_RS01350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUW56_RS01355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUW56_RS01360	COG0242	peptide deformylase activity
HUW56_RS01370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUW56_RS01370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HUW56_RS01380	COG0631	protein serine/threonine phosphatase activity
HUW56_RS01385	COG2815	serine threonine protein kinase
HUW56_RS01385	COG0515	serine threonine protein kinase
HUW56_RS01395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUW56_RS01400	COG1564	THIamine pyrophosphokinase
HUW56_RS01415	COG1302	Protein conserved in bacteria
HUW56_RS01420	COG1461	Dihydroxyacetone kinase
HUW56_RS01425	COG1760	l-serine dehydratase
HUW56_RS01430	COG1760	l-serine dehydratase
HUW56_RS01435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HUW56_RS01450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUW56_RS01455	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS01470	COG1196	nuclear chromosome segregation
HUW56_RS01475	COG0552	protein localization to endoplasmic reticulum
HUW56_RS01490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HUW56_RS01500	COG1837	Belongs to the UPF0109 family
HUW56_RS01525	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HUW56_RS01540	COG2257	FlhB HrpN YscU SpaS Family
HUW56_RS01550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HUW56_RS01555	COG0758	DNA mediated transformation
HUW56_RS01560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUW56_RS01570	COG4974	Belongs to the 'phage' integrase family
HUW56_RS01590	COG1815	bacterial-type flagellum-dependent cell motility
HUW56_RS01595	COG1558	bacterial-type flagellum-dependent cell motility
HUW56_RS01600	COG1677	Flagellar hook-basal body complex protein FliE
HUW56_RS01605	COG1766	The M ring may be actively involved in energy transduction
HUW56_RS01610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUW56_RS01615	COG1317	bacterial-type flagellum organization
HUW56_RS01620	COG1157	protein secretion by the type III secretion system
HUW56_RS01625	COG2882	bacterial-type flagellum organization
HUW56_RS01630	COG3334	PFAM MgtE intracellular
HUW56_RS01635	COG3144	bacterial-type flagellum assembly
HUW56_RS01640	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HUW56_RS01645	COG4786	Flagellar basal body rod
HUW56_RS01650	COG1582	Flagellar protein (FlbD)
HUW56_RS01655	COG1580	Controls the rotational direction of flagella during chemotaxis
HUW56_RS01660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUW56_RS01665	COG1776	CheC inhibitor of MCP methylation
HUW56_RS01665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HUW56_RS01670	COG2201	protein-glutamate methylesterase activity
HUW56_RS01675	COG3190	flagellar
HUW56_RS01680	COG1338	Plays a role in the flagellum-specific transport system
HUW56_RS01685	COG1987	bacterial-type flagellum assembly
HUW56_RS01690	COG1684	flagellar biosynthetic protein fliR
HUW56_RS01695	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUW56_RS01700	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HUW56_RS01705	COG1419	protein localization to endoplasmic reticulum
HUW56_RS01710	COG0455	bacterial-type flagellum organization
HUW56_RS01715	COG2201	protein-glutamate methylesterase activity
HUW56_RS01720	COG2198	Histidine kinase
HUW56_RS01720	COG0643	Histidine kinase
HUW56_RS01725	COG0835	chemotaxis
HUW56_RS01730	COG1776	CheC inhibitor of MCP methylation
HUW56_RS01740	COG1191	sigma factor activity
HUW56_RS01770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUW56_RS01775	COG4589	Belongs to the CDS family
HUW56_RS01785	COG0750	zinc metalloprotease
HUW56_RS01795	COG2176	DNA-directed DNA polymerase activity
HUW56_RS01805	COG0195	Participates in both transcription termination and antitermination
HUW56_RS01810	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HUW56_RS01815	COG1358	cellular component organization or biogenesis
HUW56_RS01825	COG1550	Protein conserved in bacteria
HUW56_RS01840	COG0196	riboflavin kinase activity
HUW56_RS01855	COG0726	polysaccharide deacetylase
HUW56_RS01860	COG0612	Peptidase, M16
HUW56_RS01865	COG1873	PFAM PRC-barrel domain
HUW56_RS01870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUW56_RS01875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUW56_RS01880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HUW56_RS01885	COG0527	aspartate kinase activity
HUW56_RS01895	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUW56_RS01900	COG0740	serine-type endopeptidase activity
HUW56_RS01910	COG4980	gas vesicle protein
HUW56_RS01910	COG1674	ftsk spoiiie
HUW56_RS01915	COG2188	Transcriptional regulator
HUW56_RS01920	COG2814	Major facilitator Superfamily
HUW56_RS01925	COG1846	Transcriptional regulator
HUW56_RS01930	COG1033	growth of symbiont in host cell
HUW56_RS01930	COG2409	Drug exporters of the RND superfamily
HUW56_RS01935	COG0612	Peptidase, M16
HUW56_RS01940	COG0612	Peptidase, M16
HUW56_RS01945	COG0300	oxidoreductase activity
HUW56_RS01960	COG1426	Protein conserved in bacteria
HUW56_RS01965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUW56_RS01980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUW56_RS01990	COG1692	metallophosphoesterase
HUW56_RS01995	COG2359	stage V sporulation protein S
HUW56_RS02015	COG4550	Control of competence regulator ComK, YlbF/YmcA
HUW56_RS02060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS02065	COG3425	synthase
HUW56_RS02070	COG1024	Enoyl-CoA hydratase
HUW56_RS02075	COG1024	Enoyl-CoA hydratase
HUW56_RS02080	COG3321	synthase
HUW56_RS02080	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02080	COG0300	oxidoreductase activity
HUW56_RS02080	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS02085	COG3321	synthase
HUW56_RS02085	COG4221	oxidoreductase activity
HUW56_RS02085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS02085	COG0300	oxidoreductase activity
HUW56_RS02090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS02090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS02090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS02090	COG3321	synthase
HUW56_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02090	COG3321	synthase
HUW56_RS02095	COG3321	synthase
HUW56_RS02095	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02095	COG4221	oxidoreductase activity
HUW56_RS02100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS02100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUW56_RS02100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUW56_RS02100	COG3321	synthase
HUW56_RS02105	COG2124	cytochrome p450
HUW56_RS02110	COG3209	COG3209 Rhs family protein
HUW56_RS02115	COG3619	membrane
HUW56_RS02125	COG1404	Belongs to the peptidase S8 family
HUW56_RS02135	COG4195	phage-related replication protein
HUW56_RS02140	COG1764	response to oxidative stress
HUW56_RS02150	COG2076	Multidrug Resistance protein
HUW56_RS02190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUW56_RS02195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUW56_RS02200	COG4112	unkown
HUW56_RS02205	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS02210	COG0464	growth
HUW56_RS02215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUW56_RS02220	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HUW56_RS02225	COG0789	Transcriptional regulator
HUW56_RS02230	COG0174	glutamine synthetase
HUW56_RS02270	COG2211	Major facilitator Superfamily
HUW56_RS02275	COG3507	Belongs to the glycosyl hydrolase 43 family
HUW56_RS02290	COG1070	Carbohydrate kinase
HUW56_RS02295	COG0574	Belongs to the PEP-utilizing enzyme family
HUW56_RS02295	COG3848	Pyruvate phosphate dikinase
HUW56_RS02320	COG1064	alcohol dehydrogenase
HUW56_RS02325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUW56_RS02325	COG4451	ribulose bisphosphate carboxylase, small
HUW56_RS02365	COG3397	chitin binding
HUW56_RS02385	COG5434	Belongs to the glycosyl hydrolase 28 family
HUW56_RS02390	COG0756	dUTP diphosphatase activity
HUW56_RS02395	COG4195	phage-related replication protein
HUW56_RS02430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUW56_RS02440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUW56_RS02460	COG0785	Cytochrome C biogenesis protein
HUW56_RS02465	COG2201	protein-glutamate methylesterase activity
HUW56_RS02470	COG4846	Membrane protein involved in cytochrome C biogenesis
HUW56_RS02480	COG0071	Belongs to the small heat shock protein (HSP20) family
HUW56_RS02495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUW56_RS02500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS02520	COG0824	Thioesterase
HUW56_RS02530	COG4841	protein insertion into membrane
HUW56_RS02540	COG1832	CoA-binding protein
HUW56_RS02545	COG0187	DNA topoisomerase II activity
HUW56_RS02550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUW56_RS02560	COG1115	amino acid carrier protein
HUW56_RS02570	COG1063	alcohol dehydrogenase
HUW56_RS02575	COG0800	Aldolase
HUW56_RS02580	COG1312	Catalyzes the dehydration of D-mannonate
HUW56_RS02585	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02590	COG1609	Transcriptional regulator
HUW56_RS02595	COG2271	Major facilitator Superfamily
HUW56_RS02640	COG2205	protein histidine kinase activity
HUW56_RS02645	COG0745	RESPONSE REGULATOR receiver
HUW56_RS02655	COG3507	Belongs to the glycosyl hydrolase 43 family
HUW56_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS02685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUW56_RS02690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUW56_RS02695	COG2610	gluconate transmembrane transporter activity
HUW56_RS02700	COG2124	cytochrome p450
HUW56_RS02720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUW56_RS02730	COG2246	polysaccharide biosynthetic process
HUW56_RS02740	COG0586	Pfam SNARE associated Golgi protein
HUW56_RS02745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUW56_RS02750	COG1024	Enoyl-CoA hydratase
HUW56_RS02755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUW56_RS02760	COG0511	ligase activity, forming carbon-carbon bonds
HUW56_RS02765	COG0439	Biotin carboxylase
HUW56_RS02770	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS02775	COG1960	acyl-CoA dehydrogenase activity
HUW56_RS02780	COG1649	PFAM Uncharacterised BCR, COG1649
HUW56_RS02790	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HUW56_RS02790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS02815	COG2027	D-alanyl-D-alanine carboxypeptidase
HUW56_RS02820	COG2017	converts alpha-aldose to the beta-anomer
HUW56_RS02825	COG0534	Mate efflux family protein
HUW56_RS02840	COG0582	viral genome integration into host DNA
HUW56_RS02845	COG0166	Belongs to the GPI family
HUW56_RS02850	COG0405	Gamma-glutamyltransferase
HUW56_RS02855	COG2814	Major facilitator Superfamily
HUW56_RS02860	COG0640	Transcriptional regulator
HUW56_RS02865	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUW56_RS02875	COG0604	alcohol dehydrogenase
HUW56_RS02880	COG0493	'glutamate synthase
HUW56_RS02885	COG0067	glutamate synthase
HUW56_RS02885	COG0069	glutamate synthase activity
HUW56_RS02885	COG0070	glutamate synthase
HUW56_RS02890	COG0583	DNA-binding transcription factor activity
HUW56_RS02895	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HUW56_RS02910	COG0300	oxidoreductase activity
HUW56_RS02915	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HUW56_RS02925	COG2814	Major facilitator Superfamily
HUW56_RS02930	COG1070	Carbohydrate kinase
HUW56_RS02935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUW56_RS02940	COG0243	molybdopterin cofactor binding
HUW56_RS02970	COG5444	nuclease activity
HUW56_RS02975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUW56_RS02980	COG0662	Cupin 2, conserved barrel domain protein
HUW56_RS02980	COG2207	Transcriptional regulator
HUW56_RS02985	COG1309	transcriptional regulator
HUW56_RS02990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS03000	COG0640	Transcriptional regulator
HUW56_RS03005	COG0741	lytic transglycosylase activity
HUW56_RS03010	COG2322	membrane
HUW56_RS03025	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUW56_RS03035	COG1388	LysM domain
HUW56_RS03035	COG3584	3D domain protein
HUW56_RS03040	COG0514	ATP-dependent DNA helicase (RecQ)
HUW56_RS03050	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUW56_RS03055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUW56_RS03070	COG0071	Belongs to the small heat shock protein (HSP20) family
HUW56_RS03100	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS03105	COG1657	PFAM Prenyltransferase squalene oxidase
HUW56_RS03110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUW56_RS03115	COG0733	neurotransmitter:sodium symporter activity
HUW56_RS03120	COG0385	Bile acid
HUW56_RS03125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS03130	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUW56_RS03140	COG4548	von Willebrand factor, type A
HUW56_RS03145	COG0714	Associated with various cellular activities
HUW56_RS03150	COG2032	superoxide dismutase activity
HUW56_RS03155	COG1388	LysM domain
HUW56_RS03155	COG0791	NLP P60 protein
HUW56_RS03160	COG1819	glycosyl
HUW56_RS03165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HUW56_RS03170	COG0534	Mate efflux family protein
HUW56_RS03175	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS03180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUW56_RS03185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUW56_RS03195	COG2962	Rard protein
HUW56_RS03210	COG1942	4-Oxalocrotonate Tautomerase
HUW56_RS03220	COG1733	regulation of RNA biosynthetic process
HUW56_RS03225	COG0778	Nitroreductase
HUW56_RS03230	COG0400	carboxylic ester hydrolase activity
HUW56_RS03235	COG0346	lactoylglutathione lyase activity
HUW56_RS03245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUW56_RS03255	COG2723	6-phospho-beta-galactosidase activity
HUW56_RS03260	COG2188	Transcriptional regulator
HUW56_RS03265	COG0793	Belongs to the peptidase S41A family
HUW56_RS03265	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS03270	COG2226	methyltransferase
HUW56_RS03280	COG1876	peptidase activity
HUW56_RS03300	COG0671	phosphoesterase, PA-phosphatase related
HUW56_RS03330	COG1509	lysine 2,3-aminomutase activity
HUW56_RS03335	COG0456	acetyltransferase
HUW56_RS03340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUW56_RS03345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUW56_RS03350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUW56_RS03355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUW56_RS03360	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HUW56_RS03370	COG0456	acetyltransferase
HUW56_RS03375	COG0463	Glycosyl transferase, family 2
HUW56_RS03390	COG4641	Protein conserved in bacteria
HUW56_RS03400	COG1086	Polysaccharide biosynthesis protein
HUW56_RS03435	COG0457	Tetratricopeptide repeat
HUW56_RS03445	COG3391	amine dehydrogenase activity
HUW56_RS03465	COG5444	nuclease activity
HUW56_RS03470	COG4282	regulation of fungal-type cell wall biogenesis
HUW56_RS03475	COG1525	nuclease
HUW56_RS03480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HUW56_RS03500	COG1846	Transcriptional regulator
HUW56_RS03505	COG4698	Protein conserved in bacteria
HUW56_RS03510	COG2755	lipolytic protein G-D-S-L family
HUW56_RS03515	COG1999	signal sequence binding
HUW56_RS03525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUW56_RS03530	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HUW56_RS03535	COG1272	protein, Hemolysin III
HUW56_RS03540	COG0204	Acyl-transferase
HUW56_RS03545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUW56_RS03560	COG2521	methyltransferase
HUW56_RS03560	COG2136	Putative SAM-dependent methyltransferase
HUW56_RS03575	COG1413	lyase activity
HUW56_RS03580	COG1418	mRNA catabolic process
HUW56_RS03585	COG0386	Belongs to the glutathione peroxidase family
HUW56_RS03595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUW56_RS03605	COG1278	Cold shock
HUW56_RS03625	COG0328	RNA-DNA hybrid ribonuclease activity
HUW56_RS03630	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HUW56_RS03635	COG0328	RNA-DNA hybrid ribonuclease activity
HUW56_RS03645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUW56_RS03660	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HUW56_RS03670	COG1755	Isoprenylcysteine carboxyl methyltransferase
HUW56_RS03675	COG3424	synthase
HUW56_RS03695	COG1335	isochorismatase
HUW56_RS03705	COG2233	PERMEase
HUW56_RS03715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HUW56_RS03720	COG1199	ATP-dependent helicase activity
HUW56_RS03735	COG0116	Belongs to the methyltransferase superfamily
HUW56_RS03765	COG3359	exonuclease
HUW56_RS03770	COG1111	helicase
HUW56_RS03770	COG1205	dead DEAH box helicase
HUW56_RS03775	COG2190	(PTS) system
HUW56_RS03780	COG0071	Belongs to the small heat shock protein (HSP20) family
HUW56_RS03820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUW56_RS03820	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUW56_RS03830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HUW56_RS03835	COG3935	DnaD domain protein
HUW56_RS03845	COG0436	Aminotransferase
HUW56_RS03850	COG5353	protein conserved in bacteria
HUW56_RS03860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUW56_RS03860	COG1199	ATP-dependent helicase activity
HUW56_RS03890	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS03895	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUW56_RS03910	COG1694	Mazg nucleotide pyrophosphohydrolase
HUW56_RS03915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS03930	COG4347	Protein of unknown function (DUF1405)
HUW56_RS03935	COG2010	Cytochrome c
HUW56_RS03935	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUW56_RS03940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUW56_RS03945	COG0723	plastoquinol--plastocyanin reductase activity
HUW56_RS03960	COG0457	Tetratricopeptide repeat
HUW56_RS03970	COG0287	Prephenate dehydrogenase
HUW56_RS04005	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUW56_RS04010	COG4401	Chorismate mutase type I
HUW56_RS04025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HUW56_RS04030	COG0105	UTP biosynthetic process
HUW56_RS04035	COG0142	geranyltranstransferase activity
HUW56_RS04045	COG0142	geranyltranstransferase activity
HUW56_RS04060	COG0776	regulation of translation
HUW56_RS04065	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HUW56_RS04105	COG0539	negative regulation of cytoplasmic translation
HUW56_RS04120	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HUW56_RS04125	COG2959	enzyme of heme biosynthesis
HUW56_RS04130	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS04130	COG3773	Cell wall hydrolase
HUW56_RS04135	COG2339	peptidase activity
HUW56_RS04140	COG0492	ferredoxin-NADP+ reductase activity
HUW56_RS04145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUW56_RS04150	COG4862	establishment of competence for transformation
HUW56_RS04155	COG1408	metallophosphoesterase
HUW56_RS04165	COG1388	LysM domain
HUW56_RS04170	COG1266	CAAX protease self-immunity
HUW56_RS04175	COG0514	ATP-dependent DNA helicase (RecQ)
HUW56_RS04180	COG4955	Helix-turn-helix domain
HUW56_RS04185	COG1141	Ferredoxin
HUW56_RS04190	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HUW56_RS04195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUW56_RS04205	COG1595	DNA-templated transcription, initiation
HUW56_RS04210	COG5002	protein histidine kinase activity
HUW56_RS04215	COG0745	RESPONSE REGULATOR receiver
HUW56_RS04220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUW56_RS04225	COG1333	cytochrome c biogenesis protein
HUW56_RS04230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS04235	COG1187	pseudouridine synthase activity
HUW56_RS04240	COG0700	Nucleoside recognition
HUW56_RS04245	COG2715	membrane protein required for spore maturation
HUW56_RS04250	COG1686	Belongs to the peptidase S11 family
HUW56_RS04275	COG1547	Domain of unknown function (DUF309)
HUW56_RS04280	COG0456	acetyltransferase
HUW56_RS04295	COG0307	riboflavin synthase, alpha
HUW56_RS04300	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUW56_RS04300	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HUW56_RS04310	COG0681	Belongs to the peptidase S26 family
HUW56_RS04320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUW56_RS04325	COG4086	secreted protein
HUW56_RS04330	COG0019	diaminopimelate decarboxylase activity
HUW56_RS04335	COG0697	spore germination
HUW56_RS04350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUW56_RS04370	COG1191	sigma factor activity
HUW56_RS04380	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS04385	COG1686	Belongs to the peptidase S11 family
HUW56_RS04390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HUW56_RS04395	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HUW56_RS04400	COG4974	Belongs to the 'phage' integrase family
HUW56_RS04410	COG0735	belongs to the Fur family
HUW56_RS04415	COG1300	Membrane
HUW56_RS04430	COG0281	malic enzyme
HUW56_RS04435	COG1757	Na H antiporter
HUW56_RS04440	COG1027	Aspartate ammonia-lyase
HUW56_RS04445	COG0252	asparaginase activity
HUW56_RS04450	COG1396	sequence-specific DNA binding
HUW56_RS04455	COG1379	DNA repair
HUW56_RS04460	COG0494	nUDIX hydrolase
HUW56_RS04470	COG0667	Aldo Keto reductase
HUW56_RS04480	COG1073	alpha beta
HUW56_RS04490	COG4918	Iron-sulphur cluster biosynthesis
HUW56_RS04495	COG0456	acetyltransferase
HUW56_RS04495	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUW56_RS04500	COG2329	Antibiotic biosynthesis monooxygenase
HUW56_RS04505	COG0456	acetyltransferase
HUW56_RS04510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUW56_RS04525	COG0628	permease
HUW56_RS04535	COG0346	lactoylglutathione lyase activity
HUW56_RS04545	COG3048	D-serine ammonia-lyase activity
HUW56_RS04550	COG0300	oxidoreductase activity
HUW56_RS04555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS04560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUW56_RS04565	COG1024	Enoyl-CoA hydratase
HUW56_RS04570	COG3425	synthase
HUW56_RS04575	COG2124	cytochrome p450
HUW56_RS04580	COG3321	synthase
HUW56_RS04580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS04580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS04580	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04585	COG3321	synthase
HUW56_RS04585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS04585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04590	COG0300	oxidoreductase activity
HUW56_RS04590	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS04590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04590	COG3321	synthase
HUW56_RS04595	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04595	COG0300	oxidoreductase activity
HUW56_RS04595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04595	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS04595	COG3321	synthase
HUW56_RS04600	COG3321	synthase
HUW56_RS04600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS04600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04605	COG3321	synthase
HUW56_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04605	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS04605	COG0300	oxidoreductase activity
HUW56_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS04610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUW56_RS04610	COG3321	synthase
HUW56_RS04610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS04620	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS04635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HUW56_RS04635	COG2070	2-Nitropropane dioxygenase
HUW56_RS04640	COG0250	Participates in transcription elongation, termination and antitermination
HUW56_RS04660	COG0596	Alpha beta hydrolase
HUW56_RS04675	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HUW56_RS04680	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUW56_RS04695	COG0706	membrane insertase activity
HUW56_RS04700	COG2195	Cleaves the N-terminal amino acid of tripeptides
HUW56_RS04705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUW56_RS04710	COG0346	lactoylglutathione lyase activity
HUW56_RS04725	COG4129	membrane
HUW56_RS04730	COG1126	abc transporter atp-binding protein
HUW56_RS04735	COG0765	amino acid transport
HUW56_RS04740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUW56_RS04750	COG1597	lipid kinase activity
HUW56_RS04755	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUW56_RS04760	COG0022	dehydrogenase e1 component
HUW56_RS04765	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUW56_RS04770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUW56_RS04775	COG3426	butyrate kinase activity
HUW56_RS04780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUW56_RS04785	COG0280	phosphate acetyltransferase
HUW56_RS04790	COG3290	protein histidine kinase activity
HUW56_RS04790	COG3829	transcription factor binding
HUW56_RS04800	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUW56_RS04805	COG2079	MmgE PrpD family protein
HUW56_RS04810	COG0372	Belongs to the citrate synthase family
HUW56_RS04815	COG1960	acyl-CoA dehydrogenase activity
HUW56_RS04820	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUW56_RS04825	COG0183	Belongs to the thiolase family
HUW56_RS04830	COG0584	glycerophosphoryl diester phosphodiesterase
HUW56_RS04835	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS04860	COG1902	pentaerythritol trinitrate reductase activity
HUW56_RS04875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUW56_RS04880	COG0745	RESPONSE REGULATOR receiver
HUW56_RS04885	COG0750	zinc metalloprotease
HUW56_RS04890	COG0497	DNA recombination
HUW56_RS04900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HUW56_RS04910	COG0142	geranyltranstransferase activity
HUW56_RS04920	COG1570	exodeoxyribonuclease VII activity
HUW56_RS04935	COG1302	Protein conserved in bacteria
HUW56_RS04940	COG0439	Biotin carboxylase
HUW56_RS04945	COG0511	ligase activity, forming carbon-carbon bonds
HUW56_RS04985	COG3854	ATPases associated with a variety of cellular activities
HUW56_RS05000	COG0006	proline dipeptidase activity
HUW56_RS05010	COG3872	metal-dependent enzyme
HUW56_RS05020	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUW56_RS05035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUW56_RS05055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUW56_RS05070	COG1396	sequence-specific DNA binding
HUW56_RS05080	COG0681	Belongs to the peptidase S26 family
HUW56_RS05105	COG4940	Competence protein ComGF
HUW56_RS05115	COG4970	Tfp pilus assembly protein FimT
HUW56_RS05120	COG4537	Required for transformation and DNA binding
HUW56_RS05125	COG1459	type II secretion system
HUW56_RS05130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HUW56_RS05135	COG0598	Magnesium transport protein CorA
HUW56_RS05140	COG1253	flavin adenine dinucleotide binding
HUW56_RS05145	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS05155	COG1393	Belongs to the ArsC family
HUW56_RS05165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS05175	COG0011	TIGRFAM Protein of
HUW56_RS05185	COG2866	Carboxypeptidase
HUW56_RS05190	COG1940	carbohydrate kinase activity
HUW56_RS05195	COG4483	Protein conserved in bacteria
HUW56_RS05200	COG1757	Na H antiporter
HUW56_RS05210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUW56_RS05225	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUW56_RS05230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUW56_RS05235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUW56_RS05240	COG0581	inorganic phosphate transmembrane transporter activity
HUW56_RS05245	COG0573	inorganic phosphate transmembrane transporter activity
HUW56_RS05250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUW56_RS05260	COG0477	Major facilitator Superfamily
HUW56_RS05265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HUW56_RS05270	COG2839	Protein conserved in bacteria
HUW56_RS05275	COG5521	maltodextrose utilization protein MalA
HUW56_RS05280	COG1388	LysM domain
HUW56_RS05290	COG4709	membrane
HUW56_RS05295	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HUW56_RS05300	COG0735	belongs to the Fur family
HUW56_RS05305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS05320	COG0513	Belongs to the DEAD box helicase family
HUW56_RS05335	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUW56_RS05340	COG2384	SAM-dependent methyltransferase
HUW56_RS05345	COG2010	Cytochrome c
HUW56_RS05350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUW56_RS05355	COG0358	DNA primase activity
HUW56_RS05370	COG0517	IMP dehydrogenase activity
HUW56_RS05375	COG0751	glycine-tRNA ligase activity
HUW56_RS05395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUW56_RS05400	COG0295	cytidine deaminase activity
HUW56_RS05405	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HUW56_RS05415	COG1480	7TM receptor with intracellular HD hydrolase
HUW56_RS05420	COG1702	phosphate starvation-inducible protein PhoH
HUW56_RS05425	COG0561	phosphatase activity
HUW56_RS05440	COG4864	UPF0365 protein
HUW56_RS05445	COG1030	water channel activity
HUW56_RS05450	COG1610	YqeY-like protein
HUW56_RS05460	COG1283	sodium-dependent phosphate transmembrane transporter activity
HUW56_RS05465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUW56_RS05470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUW56_RS05500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUW56_RS05515	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS05530	COG1466	dna polymerase III delta subunit
HUW56_RS05545	COG2333	competence protein COMEC
HUW56_RS05545	COG0658	competence protein
HUW56_RS05550	COG2131	deaminase
HUW56_RS05555	COG1555	photosystem II stabilization
HUW56_RS05555	COG1596	polysaccharide export
HUW56_RS05560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUW56_RS05565	COG2226	methyltransferase
HUW56_RS05570	COG0799	negative regulation of ribosome biogenesis
HUW56_RS05575	COG1713	HD superfamily hydrolase involved in NAD metabolism
HUW56_RS05585	COG1534	Rna-binding protein
HUW56_RS05590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUW56_RS05595	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HUW56_RS05600	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HUW56_RS05610	COG2755	lipolytic protein G-D-S-L family
HUW56_RS05620	COG0398	Pfam SNARE associated Golgi protein
HUW56_RS05645	COG1794	racemase activity, acting on amino acids and derivatives
HUW56_RS05660	COG1733	regulation of RNA biosynthetic process
HUW56_RS05665	COG0656	L-ascorbic acid biosynthetic process
HUW56_RS05695	COG3677	Transposase
HUW56_RS05735	COG0642	Histidine kinase
HUW56_RS05735	COG5002	protein histidine kinase activity
HUW56_RS05740	COG0745	RESPONSE REGULATOR receiver
HUW56_RS05745	COG2311	Membrane
HUW56_RS05755	COG0454	-acetyltransferase
HUW56_RS05760	COG0563	adenylate kinase activity
HUW56_RS05765	COG2814	Major facilitator Superfamily
HUW56_RS05775	COG0456	acetyltransferase
HUW56_RS05780	COG2318	DinB family
HUW56_RS05790	COG0561	phosphatase activity
HUW56_RS05795	COG0561	phosphatase activity
HUW56_RS05805	COG1482	cell wall glycoprotein biosynthetic process
HUW56_RS05810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUW56_RS05810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS05810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HUW56_RS05815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS05815	COG3711	transcriptional antiterminator
HUW56_RS05825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUW56_RS05830	COG0583	DNA-binding transcription factor activity
HUW56_RS05835	COG2814	Major facilitator Superfamily
HUW56_RS05840	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUW56_RS05840	COG2124	cytochrome p450
HUW56_RS05845	COG1309	transcriptional regulator
HUW56_RS05850	COG2226	methyltransferase
HUW56_RS05865	COG2116	formate transmembrane transporter activity
HUW56_RS05870	COG5609	conserved protein (DUF2294)
HUW56_RS05875	COG3383	formate dehydrogenase (NAD+) activity
HUW56_RS05880	COG2427	Protein of unknown function (DUF1641)
HUW56_RS05890	COG0626	cystathionine gamma-synthase activity
HUW56_RS05895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUW56_RS05920	COG0768	penicillin binding
HUW56_RS05945	COG4122	O-methyltransferase activity
HUW56_RS05950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUW56_RS05975	COG0628	permease
HUW56_RS05980	COG1126	abc transporter atp-binding protein
HUW56_RS05985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUW56_RS05990	COG0765	amino acid transport
HUW56_RS05995	COG0765	amino acid transport
HUW56_RS06010	COG3881	PFAM PRC-barrel domain
HUW56_RS06015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUW56_RS06020	COG0457	Tetratricopeptide repeat
HUW56_RS06030	COG1104	cysteine desulfurase activity
HUW56_RS06035	COG1959	2 iron, 2 sulfur cluster binding
HUW56_RS06040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HUW56_RS06045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HUW56_RS06070	COG3103	Sh3 type 3 domain protein
HUW56_RS06070	COG4991	sh3 domain protein
HUW56_RS06070	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS06080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUW56_RS06090	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HUW56_RS06090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HUW56_RS06095	COG5416	Lipopolysaccharide assembly protein A domain
HUW56_RS06100	COG0490	domain, Protein
HUW56_RS06105	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUW56_RS06105	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUW56_RS06115	COG2244	polysaccharide biosynthetic process
HUW56_RS06120	COG2323	membrane
HUW56_RS06130	COG1862	Preprotein translocase
HUW56_RS06170	COG1388	LysM domain
HUW56_RS06180	COG0157	Belongs to the NadC ModD family
HUW56_RS06185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUW56_RS06190	COG1104	cysteine desulfurase activity
HUW56_RS06195	COG1827	regulation of RNA biosynthetic process
HUW56_RS06200	COG0077	Prephenate dehydratase
HUW56_RS06215	COG3290	protein histidine kinase activity
HUW56_RS06220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUW56_RS06225	COG2868	ribosomal protein
HUW56_RS06235	COG1994	Peptidase M50
HUW56_RS06240	COG0739	heme binding
HUW56_RS06245	COG2894	cell division
HUW56_RS06250	COG0850	regulation of cytokinetic process
HUW56_RS06255	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HUW56_RS06265	COG1077	Cell shape determining protein MreB Mrl
HUW56_RS06285	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HUW56_RS06290	COG0285	dihydrofolate synthase activity
HUW56_RS06295	COG0525	valine-tRNA ligase activity
HUW56_RS06305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUW56_RS06310	COG1388	LysM domain
HUW56_RS06320	COG0113	porphobilinogen synthase activity
HUW56_RS06325	COG1587	Uroporphyrinogen-III synthase
HUW56_RS06335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUW56_RS06355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUW56_RS06360	COG1067	ATP-dependent peptidase activity
HUW56_RS06360	COG0470	DNA polymerase III
HUW56_RS06375	COG1477	protein flavinylation
HUW56_RS06375	COG0457	Tetratricopeptide repeat
HUW56_RS06390	COG0473	3-isopropylmalate dehydrogenase activity
HUW56_RS06405	COG0440	acetolactate synthase activity
HUW56_RS06410	COG0028	Belongs to the TPP enzyme family
HUW56_RS06435	COG0622	Phosphoesterase
HUW56_RS06440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUW56_RS06450	COG5401	PFAM Sporulation and spore germination
HUW56_RS06460	COG1846	Transcriptional regulator
HUW56_RS06465	COG2197	response regulator
HUW56_RS06470	COG0824	Thioesterase
HUW56_RS06475	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUW56_RS06480	COG1053	succinate dehydrogenase
HUW56_RS06485	COG2009	succinate dehydrogenase
HUW56_RS06490	COG1719	4-vinyl reductase, 4VR
HUW56_RS06495	COG0527	aspartate kinase activity
HUW56_RS06505	COG3118	belongs to the thioredoxin family
HUW56_RS06510	COG3534	alpha-L-arabinofuranosidase
HUW56_RS06515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUW56_RS06520	COG2086	electron transfer activity
HUW56_RS06525	COG1024	Enoyl-CoA hydratase
HUW56_RS06530	COG1309	transcriptional regulator
HUW56_RS06535	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS06545	COG3766	membrane
HUW56_RS06555	COG1796	DNA polymerase
HUW56_RS06555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUW56_RS06560	COG1286	toxin biosynthetic process
HUW56_RS06575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUW56_RS06575	COG0072	phenylalanine-tRNA ligase activity
HUW56_RS06580	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUW56_RS06585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUW56_RS06595	COG3835	regulator
HUW56_RS06600	COG0277	FAD linked oxidase domain protein
HUW56_RS06605	COG0247	lactate metabolic process
HUW56_RS06610	COG1966	Carbon starvation protein
HUW56_RS06615	COG3534	alpha-L-arabinofuranosidase
HUW56_RS06620	COG0395	ABC-type sugar transport system, permease component
HUW56_RS06625	COG1175	transmembrane transport
HUW56_RS06630	COG1653	transport
HUW56_RS06640	COG0647	UMP catabolic process
HUW56_RS06645	COG0235	Class ii aldolase
HUW56_RS06650	COG1069	ribulokinase activity
HUW56_RS06655	COG2160	L-arabinose isomerase activity
HUW56_RS06660	COG3507	Belongs to the glycosyl hydrolase 43 family
HUW56_RS06665	COG1363	Peptidase, m42
HUW56_RS06675	COG3326	Membrane
HUW56_RS06690	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUW56_RS06695	COG1346	cytolysis
HUW56_RS06700	COG1380	Effector of murein hydrolase LrgA
HUW56_RS06705	COG3279	Response regulator of the LytR AlgR family
HUW56_RS06710	COG3275	phosphorelay sensor kinase activity
HUW56_RS06715	COG1011	Hydrolase
HUW56_RS06730	COG0398	Pfam SNARE associated Golgi protein
HUW56_RS06735	COG1484	DNA-dependent DNA replication
HUW56_RS06740	COG3611	Membrane attachment protein
HUW56_RS06755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUW56_RS06760	COG1733	regulation of RNA biosynthetic process
HUW56_RS06765	COG2814	Major facilitator Superfamily
HUW56_RS06770	COG0656	L-ascorbic acid biosynthetic process
HUW56_RS06775	COG0237	dephospho-CoA kinase activity
HUW56_RS06780	COG1971	Probably functions as a manganese efflux pump
HUW56_RS06785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUW56_RS06790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUW56_RS06790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HUW56_RS06795	COG5002	protein histidine kinase activity
HUW56_RS06800	COG0745	RESPONSE REGULATOR receiver
HUW56_RS06810	COG0538	isocitrate dehydrogenase activity
HUW56_RS06815	COG0372	Belongs to the citrate synthase family
HUW56_RS06845	COG0628	permease
HUW56_RS06850	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUW56_RS06855	COG0469	pyruvate kinase activity
HUW56_RS06875	COG0281	malic enzyme
HUW56_RS06880	COG0587	DNA-directed DNA polymerase activity
HUW56_RS06900	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HUW56_RS06910	COG4109	DRTGG domain
HUW56_RS06920	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS06935	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUW56_RS06945	COG0827	DNA restriction-modification system
HUW56_RS06950	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUW56_RS06955	COG3874	Sporulation protein YtfJ
HUW56_RS06965	COG1714	RDD family
HUW56_RS06970	COG0616	signal peptide processing
HUW56_RS06975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUW56_RS06980	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HUW56_RS06985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUW56_RS07000	COG1104	cysteine desulfurase activity
HUW56_RS07005	COG1114	Component of the transport system for branched-chain amino acids
HUW56_RS07015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUW56_RS07020	COG1309	transcriptional regulator
HUW56_RS07025	COG1956	GAF domain-containing protein
HUW56_RS07030	COG2199	diguanylate cyclase activity
HUW56_RS07030	COG2203	Gaf domain
HUW56_RS07040	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS07045	COG4282	regulation of fungal-type cell wall biogenesis
HUW56_RS07090	COG1017	nitric oxide dioxygenase activity
HUW56_RS07090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUW56_RS07105	COG0693	protein deglycase activity
HUW56_RS07120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUW56_RS07125	COG1378	Sugar-specific transcriptional regulator TrmB
HUW56_RS07145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUW56_RS07150	COG0454	-acetyltransferase
HUW56_RS07155	COG0517	IMP dehydrogenase activity
HUW56_RS07160	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUW56_RS07165	COG1360	Flagellar Motor Protein
HUW56_RS07170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HUW56_RS07175	COG1609	Transcriptional regulator
HUW56_RS07180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HUW56_RS07180	COG1605	Chorismate mutase
HUW56_RS07185	COG3118	belongs to the thioredoxin family
HUW56_RS07190	COG4980	gas vesicle protein
HUW56_RS07195	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HUW56_RS07205	COG1674	ftsk spoiiie
HUW56_RS07210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUW56_RS07220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS07230	COG1363	Peptidase, m42
HUW56_RS07235	COG5584	Small secreted protein
HUW56_RS07240	COG0281	malic enzyme
HUW56_RS07245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS07260	COG0510	thiamine kinase activity
HUW56_RS07265	COG1597	lipid kinase activity
HUW56_RS07275	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HUW56_RS07280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUW56_RS07285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUW56_RS07290	COG2252	PERMEase
HUW56_RS07295	COG4473	ABC transporter
HUW56_RS07300	COG1131	(ABC) transporter
HUW56_RS07305	COG1349	DNA-binding transcription factor activity
HUW56_RS07310	COG1187	pseudouridine synthase activity
HUW56_RS07315	COG2244	polysaccharide biosynthetic process
HUW56_RS07320	COG2081	HI0933 family
HUW56_RS07325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HUW56_RS07335	COG1609	Transcriptional regulator
HUW56_RS07340	COG1653	transport
HUW56_RS07345	COG1175	transmembrane transport
HUW56_RS07350	COG0395	ABC-type sugar transport system, permease component
HUW56_RS07355	COG1486	melibiose metabolic process
HUW56_RS07365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUW56_RS07380	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS07380	COG2202	Pas domain
HUW56_RS07385	COG2814	Major facilitator Superfamily
HUW56_RS07390	COG5522	Integral membrane protein (intg_mem_TP0381)
HUW56_RS07395	COG0577	efflux transmembrane transporter activity
HUW56_RS07400	COG1136	(ABC) transporter
HUW56_RS07405	COG2205	protein histidine kinase activity
HUW56_RS07410	COG0745	RESPONSE REGULATOR receiver
HUW56_RS07415	COG0577	efflux transmembrane transporter activity
HUW56_RS07420	COG1136	(ABC) transporter
HUW56_RS07440	COG1131	(ABC) transporter
HUW56_RS07445	COG1725	Transcriptional regulator
HUW56_RS07455	COG1242	4 iron, 4 sulfur cluster binding
HUW56_RS07460	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HUW56_RS07470	COG0584	glycerophosphoryl diester phosphodiesterase
HUW56_RS07480	COG2267	carboxylic ester hydrolase activity
HUW56_RS07485	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUW56_RS07490	COG1113	amino acid transport
HUW56_RS07495	COG0367	asparagine synthase
HUW56_RS07515	COG1506	peptidase
HUW56_RS07520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUW56_RS07525	COG1116	anion transmembrane transporter activity
HUW56_RS07530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUW56_RS07535	COG0494	nUDIX hydrolase
HUW56_RS07540	COG4824	toxin secretion phage lysis holin
HUW56_RS07545	COG0783	Belongs to the Dps family
HUW56_RS07570	COG0288	reversible hydration of carbon dioxide
HUW56_RS07580	COG1271	oxidase subunit
HUW56_RS07585	COG1294	oxidase, subunit
HUW56_RS07600	COG4948	Mandelate Racemase Muconate Lactonizing
HUW56_RS07610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUW56_RS07615	COG0596	Alpha beta hydrolase
HUW56_RS07625	COG1169	isochorismate synthase
HUW56_RS07630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HUW56_RS07635	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HUW56_RS07760	COG3859	Proton-coupled thiamine transporter YuaJ
HUW56_RS07765	COG2268	Band 7 protein
HUW56_RS07770	COG1585	Membrane protein implicated in regulation of membrane protease activity
HUW56_RS07775	COG2318	DinB family
HUW56_RS07785	COG1454	alcohol dehydrogenase
HUW56_RS07790	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS07795	COG1510	regulation of RNA biosynthetic process
HUW56_RS07805	COG0569	domain protein
HUW56_RS07810	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUW56_RS07815	COG1017	nitric oxide dioxygenase activity
HUW56_RS07815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUW56_RS07840	COG0628	permease
HUW56_RS07845	COG0673	inositol 2-dehydrogenase activity
HUW56_RS07850	COG0693	protein deglycase activity
HUW56_RS07855	COG0840	transmembrane signaling receptor activity
HUW56_RS07860	COG0840	transmembrane signaling receptor activity
HUW56_RS07865	COG0840	transmembrane signaling receptor activity
HUW56_RS07870	COG0840	transmembrane signaling receptor activity
HUW56_RS07885	COG2070	2-Nitropropane dioxygenase
HUW56_RS07890	COG0432	Pfam Uncharacterised protein family UPF0047
HUW56_RS07895	COG0366	Alpha amylase catalytic
HUW56_RS07900	COG1253	flavin adenine dinucleotide binding
HUW56_RS07905	COG2738	Putative neutral zinc metallopeptidase
HUW56_RS07920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HUW56_RS07945	COG1335	isochorismatase
HUW56_RS07950	COG1979	alcohol dehydrogenase
HUW56_RS07955	COG1979	alcohol dehydrogenase
HUW56_RS07960	COG2155	Conserved Protein
HUW56_RS07965	COG1098	S1 RNA binding domain
HUW56_RS07970	COG0436	Aminotransferase
HUW56_RS07975	COG1522	sequence-specific DNA binding
HUW56_RS07980	COG2267	carboxylic ester hydrolase activity
HUW56_RS07990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUW56_RS07995	COG2205	protein histidine kinase activity
HUW56_RS08005	COG5018	Exonuclease
HUW56_RS08010	COG2814	Major facilitator Superfamily
HUW56_RS08015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUW56_RS08020	COG3011	Protein conserved in bacteria
HUW56_RS08030	COG3290	protein histidine kinase activity
HUW56_RS08035	COG4565	transcriptional regulatory protein
HUW56_RS08065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUW56_RS08065	COG2111	Na H antiporter
HUW56_RS08070	COG2111	Na H antiporter
HUW56_RS08075	COG1006	Multisubunit Na H antiporter MnhC subunit
HUW56_RS08080	COG0651	ATP synthesis coupled electron transport
HUW56_RS08085	COG1863	multisubunit Na H antiporter MnhE subunit
HUW56_RS08090	COG2212	antiporter activity
HUW56_RS08095	COG1320	monovalent cation:proton antiporter activity
HUW56_RS08100	COG2050	protein possibly involved in aromatic compounds catabolism
HUW56_RS08105	COG2197	response regulator
HUW56_RS08110	COG4585	Histidine kinase
HUW56_RS08140	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HUW56_RS08145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUW56_RS08150	COG1335	isochorismatase
HUW56_RS08155	COG5506	Protein of unknown function (DUF1694)
HUW56_RS08170	COG0628	permease
HUW56_RS08180	COG1418	mRNA catabolic process
HUW56_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS08195	COG1511	domain protein
HUW56_RS08200	COG0433	COG0433 Predicted ATPase
HUW56_RS08200	COG1674	ftsk spoiiie
HUW56_RS08205	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUW56_RS08210	COG5417	Belongs to the EsaB family
HUW56_RS08215	COG4842	Belongs to the WXG100 family
HUW56_RS08220	COG2508	Transcriptional regulator
HUW56_RS08220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUW56_RS08225	COG0686	Belongs to the AlaDH PNT family
HUW56_RS08230	COG5634	Uncharacterized conserved protein (DUF2278)
HUW56_RS08235	COG3251	PFAM MbtH domain protein
HUW56_RS08240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS08245	COG1535	isochorismatase
HUW56_RS08245	COG3433	isochorismatase activity
HUW56_RS08250	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUW56_RS08255	COG1169	isochorismate synthase
HUW56_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS08265	COG2819	hydrolase of the alpha beta superfamily
HUW56_RS08270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUW56_RS08275	COG1268	BioY protein
HUW56_RS08280	COG2056	Na+-H+ antiporter family
HUW56_RS08290	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HUW56_RS08295	COG3584	3D domain protein
HUW56_RS08310	COG1252	NADH dehydrogenase
HUW56_RS08340	COG1131	(ABC) transporter
HUW56_RS08360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUW56_RS08365	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HUW56_RS08370	COG0316	Belongs to the HesB IscA family
HUW56_RS08380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUW56_RS08390	COG1252	NADH dehydrogenase
HUW56_RS08395	COG4837	Protein of unknown function (DUF1462)
HUW56_RS08400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HUW56_RS08405	COG1506	peptidase
HUW56_RS08405	COG4946	Tricorn protease homolog
HUW56_RS08405	COG0823	Involved in the tonB-independent uptake of proteins
HUW56_RS08415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUW56_RS08420	COG0460	homoserine dehydrogenase
HUW56_RS08425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUW56_RS08430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HUW56_RS08435	COG0647	UMP catabolic process
HUW56_RS08440	COG2445	Protein of unknown function DUF86
HUW56_RS08445	COG4470	Protein conserved in bacteria
HUW56_RS08455	COG0739	heme binding
HUW56_RS08465	COG0737	Belongs to the 5'-nucleotidase family
HUW56_RS08470	COG0730	response to heat
HUW56_RS08475	COG1801	Protein of unknown function DUF72
HUW56_RS08490	COG2508	Transcriptional regulator
HUW56_RS08510	COG2814	Major facilitator Superfamily
HUW56_RS08515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HUW56_RS08520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUW56_RS08525	COG2356	endonuclease I
HUW56_RS08530	COG3842	ATPase activity
HUW56_RS08535	COG2188	Transcriptional regulator
HUW56_RS08540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUW56_RS08545	COG0395	ABC-type sugar transport system, permease component
HUW56_RS08550	COG1175	transmembrane transport
HUW56_RS08555	COG1653	transport
HUW56_RS08560	COG2222	sugar isomerase
HUW56_RS08565	COG0789	Transcriptional regulator
HUW56_RS08590	COG0322	excinuclease ABC activity
HUW56_RS08595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUW56_RS08615	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS08620	COG0719	Fe-S assembly protein
HUW56_RS08625	COG0822	iron-sulfur transferase activity
HUW56_RS08630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUW56_RS08635	COG0719	Fe-S assembly protein
HUW56_RS08640	COG0396	ATPase activity
HUW56_RS08650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUW56_RS08655	COG1464	Belongs to the NlpA lipoprotein family
HUW56_RS08660	COG2011	ABC-type metal ion transport system permease component
HUW56_RS08665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUW56_RS08675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS08680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HUW56_RS08695	COG1393	Belongs to the ArsC family
HUW56_RS08700	COG1960	acyl-CoA dehydrogenase activity
HUW56_RS08705	COG0183	Belongs to the thiolase family
HUW56_RS08710	COG1024	Enoyl-CoA hydratase
HUW56_RS08710	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUW56_RS08730	COG5577	PFAM Coat F domain
HUW56_RS08735	COG1846	Transcriptional regulator
HUW56_RS08740	COG0477	Major facilitator Superfamily
HUW56_RS08745	COG1942	4-Oxalocrotonate Tautomerase
HUW56_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS08755	COG0583	DNA-binding transcription factor activity
HUW56_RS08765	COG0583	DNA-binding transcription factor activity
HUW56_RS08785	COG1120	ATPase activity
HUW56_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS08805	COG0783	Belongs to the Dps family
HUW56_RS08810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUW56_RS08815	COG0745	RESPONSE REGULATOR receiver
HUW56_RS08820	COG2770	Histidine kinase
HUW56_RS08820	COG2205	protein histidine kinase activity
HUW56_RS08830	COG1309	transcriptional regulator
HUW56_RS08835	COG0114	fumarate hydratase activity
HUW56_RS08845	COG0697	spore germination
HUW56_RS08850	COG0814	amino acid
HUW56_RS08860	COG2197	response regulator
HUW56_RS08865	COG4585	Histidine kinase
HUW56_RS08870	COG4758	membrane
HUW56_RS08875	COG3595	metallopeptidase activity
HUW56_RS08880	COG1842	Phage shock protein A
HUW56_RS08885	COG4758	membrane
HUW56_RS08890	COG2814	Major facilitator Superfamily
HUW56_RS08895	COG2096	Adenosyltransferase
HUW56_RS08900	COG1120	ATPase activity
HUW56_RS08905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS08910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUW56_RS08915	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS08920	COG3386	PFAM SMP-30 Gluconolaconase
HUW56_RS08925	COG2205	protein histidine kinase activity
HUW56_RS08930	COG0745	RESPONSE REGULATOR receiver
HUW56_RS08940	COG1191	sigma factor activity
HUW56_RS08950	COG2140	Oxalate decarboxylase
HUW56_RS08960	COG1120	ATPase activity
HUW56_RS08965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS08970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS08975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUW56_RS08980	COG0531	amino acid
HUW56_RS08990	COG1988	membrane-bound metal-dependent
HUW56_RS08995	COG1368	sulfuric ester hydrolase activity
HUW56_RS09000	COG1910	domain protein
HUW56_RS09005	COG0725	ABC transporter, periplasmic molybdate-binding protein
HUW56_RS09010	COG4149	molybdate abc transporter
HUW56_RS09015	COG2197	response regulator
HUW56_RS09020	COG3850	Histidine kinase
HUW56_RS09025	COG1131	(ABC) transporter
HUW56_RS09035	COG0842	Transport permease protein
HUW56_RS09040	COG0656	L-ascorbic acid biosynthetic process
HUW56_RS09060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUW56_RS09065	COG3973	AAA domain
HUW56_RS09070	COG2860	membrane
HUW56_RS09080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HUW56_RS09085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HUW56_RS09090	COG2217	Heavy metal translocating P-type atpase
HUW56_RS09095	COG2217	Heavy metal translocating P-type atpase
HUW56_RS09100	COG2608	mercury ion transmembrane transporter activity
HUW56_RS09105	COG1937	Protein conserved in bacteria
HUW56_RS09110	COG0673	inositol 2-dehydrogenase activity
HUW56_RS09120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS09125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HUW56_RS09130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS09135	COG1126	abc transporter atp-binding protein
HUW56_RS09140	COG0765	amino acid transport
HUW56_RS09145	COG0765	amino acid transport
HUW56_RS09150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUW56_RS09155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUW56_RS09160	COG0454	-acetyltransferase
HUW56_RS09165	COG0583	DNA-binding transcription factor activity
HUW56_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS09210	COG0557	exoribonuclease II activity
HUW56_RS09215	COG1647	Serine aminopeptidase, S33
HUW56_RS09220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUW56_RS09225	COG1476	TRANSCRIPTIONal
HUW56_RS09230	COG1396	sequence-specific DNA binding
HUW56_RS09235	COG1396	sequence-specific DNA binding
HUW56_RS09240	COG1733	regulation of RNA biosynthetic process
HUW56_RS09265	COG1131	(ABC) transporter
HUW56_RS09270	COG1174	glycine betaine transport
HUW56_RS09275	COG1732	Glycine betaine
HUW56_RS09280	COG1174	glycine betaine transport
HUW56_RS09285	COG0517	IMP dehydrogenase activity
HUW56_RS09285	COG1125	glycine betaine transport
HUW56_RS09290	COG1510	regulation of RNA biosynthetic process
HUW56_RS09295	COG1174	glycine betaine transport
HUW56_RS09300	COG1732	Glycine betaine
HUW56_RS09305	COG1174	glycine betaine transport
HUW56_RS09310	COG1125	glycine betaine transport
HUW56_RS09310	COG0517	IMP dehydrogenase activity
HUW56_RS09315	COG1510	regulation of RNA biosynthetic process
HUW56_RS09320	COG2095	MarC family integral membrane protein
HUW56_RS09325	COG3064	Membrane
HUW56_RS09330	COG4640	response to antibiotic
HUW56_RS09335	COG0456	acetyltransferase
HUW56_RS09350	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUW56_RS09370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS09375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUW56_RS09385	COG2234	aminopeptidase activity
HUW56_RS09405	COG0126	phosphoglycerate kinase activity
HUW56_RS09410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUW56_RS09415	COG2390	Transcriptional regulator
HUW56_RS09420	COG2814	Major facilitator Superfamily
HUW56_RS09425	COG1609	Transcriptional regulator
HUW56_RS09430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS09440	COG0583	DNA-binding transcription factor activity
HUW56_RS09445	COG0697	spore germination
HUW56_RS09450	COG1113	amino acid transport
HUW56_RS09455	COG1609	Transcriptional regulator
HUW56_RS09465	COG0561	phosphatase activity
HUW56_RS09470	COG1737	Transcriptional regulator
HUW56_RS09475	COG1070	Carbohydrate kinase
HUW56_RS09515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS09520	COG2186	Transcriptional regulator
HUW56_RS09525	COG1620	l-lactate permease
HUW56_RS09530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HUW56_RS09540	COG5039	Polysaccharide pyruvyl transferase
HUW56_RS09545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUW56_RS09550	COG0110	maltose O-acetyltransferase activity
HUW56_RS09555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HUW56_RS09560	COG2244	polysaccharide biosynthetic process
HUW56_RS09565	COG1216	Glycosyl transferase, family 2
HUW56_RS09570	COG5039	Polysaccharide pyruvyl transferase
HUW56_RS09575	COG1216	Glycosyl transferase, family 2
HUW56_RS09585	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS09590	COG1215	transferase activity, transferring glycosyl groups
HUW56_RS09595	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS09600	COG1086	Polysaccharide biosynthesis protein
HUW56_RS09605	COG0489	protein tyrosine kinase activity
HUW56_RS09610	COG3944	biosynthesis protein
HUW56_RS09615	COG1396	sequence-specific DNA binding
HUW56_RS09620	COG2272	Belongs to the type-B carboxylesterase lipase family
HUW56_RS09625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUW56_RS09630	COG2364	Membrane
HUW56_RS09635	COG0456	acetyltransferase
HUW56_RS09640	COG3479	Phenolic acid decarboxylase
HUW56_RS09690	COG2223	nitrite transmembrane transporter activity
HUW56_RS09695	COG1609	Transcriptional regulator
HUW56_RS09705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUW56_RS09710	COG0366	Alpha amylase catalytic
HUW56_RS09720	COG5521	maltodextrose utilization protein MalA
HUW56_RS09725	COG3833	ABC-type maltose transport systems, permease component
HUW56_RS09730	COG1175	transmembrane transport
HUW56_RS09735	COG2182	Extracellular solute-binding protein
HUW56_RS09740	COG0366	Alpha amylase catalytic
HUW56_RS09745	COG1609	Transcriptional regulator
HUW56_RS09750	COG1611	Belongs to the LOG family
HUW56_RS09755	COG1694	Mazg nucleotide pyrophosphohydrolase
HUW56_RS09760	COG0659	secondary active sulfate transmembrane transporter activity
HUW56_RS09765	COG0288	reversible hydration of carbon dioxide
HUW56_RS09770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HUW56_RS09775	COG4290	ribonuclease
HUW56_RS09780	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUW56_RS09785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS09795	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUW56_RS09805	COG1051	belongs to the nudix hydrolase family
HUW56_RS09810	COG0492	ferredoxin-NADP+ reductase activity
HUW56_RS09815	COG0791	NLP P60 protein
HUW56_RS09815	COG3883	PFAM NLP P60 protein
HUW56_RS09820	COG0457	Tetratricopeptide repeat
HUW56_RS09825	COG5002	protein histidine kinase activity
HUW56_RS09830	COG0745	RESPONSE REGULATOR receiver
HUW56_RS09835	COG1132	(ABC) transporter
HUW56_RS09840	COG0140	phosphoribosyl-ATP diphosphatase activity
HUW56_RS09840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HUW56_RS09865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUW56_RS09880	COG4990	cell redox homeostasis
HUW56_RS09885	COG0110	maltose O-acetyltransferase activity
HUW56_RS09905	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HUW56_RS09915	COG2188	Transcriptional regulator
HUW56_RS09920	COG1309	transcriptional regulator
HUW56_RS09925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HUW56_RS09930	COG1950	PFAM Membrane protein of
HUW56_RS09935	COG1983	PspC domain protein
HUW56_RS09940	COG3595	metallopeptidase activity
HUW56_RS09955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUW56_RS09965	COG4897	Protein conserved in bacteria
HUW56_RS09970	COG0574	Belongs to the PEP-utilizing enzyme family
HUW56_RS09970	COG3848	Pyruvate phosphate dikinase
HUW56_RS09975	COG1309	transcriptional regulator
HUW56_RS09980	COG2814	Major facilitator Superfamily
HUW56_RS09995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUW56_RS10005	COG0793	Belongs to the peptidase S41A family
HUW56_RS10005	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS10010	COG3420	alginic acid biosynthetic process
HUW56_RS10015	COG2177	Part of the ABC transporter FtsEX involved in
HUW56_RS10020	COG2884	Cell division ATP-binding protein ftsE
HUW56_RS10025	COG2010	Cytochrome c
HUW56_RS10030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS10045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUW56_RS10060	COG1516	flagellar protein fliS
HUW56_RS10065	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HUW56_RS10070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUW56_RS10090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HUW56_RS10095	COG1256	bacterial-type flagellum assembly
HUW56_RS10095	COG4786	Flagellar basal body rod
HUW56_RS10100	COG3418	PFAM FlgN family protein
HUW56_RS10105	COG2747	anti-sigma28 factor FlgM
HUW56_RS10115	COG1040	competence protein
HUW56_RS10125	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HUW56_RS10130	COG1307	EDD domain protein, DegV family
HUW56_RS10135	COG2197	response regulator
HUW56_RS10140	COG4585	Histidine kinase
HUW56_RS10145	COG1739	Uncharacterized protein family UPF0029
HUW56_RS10150	COG1316	TRANSCRIPTIONal
HUW56_RS10155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUW56_RS10160	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS10165	COG1215	transferase activity, transferring glycosyl groups
HUW56_RS10170	COG3206	protein involved in exopolysaccharide biosynthesis
HUW56_RS10175	COG3307	-O-antigen
HUW56_RS10180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUW56_RS10185	COG0297	glycogen (starch) synthase activity
HUW56_RS10185	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS10190	COG2244	polysaccharide biosynthetic process
HUW56_RS10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS10200	COG2247	cell wall binding repeat
HUW56_RS10205	COG2247	cell wall binding repeat
HUW56_RS10205	COG2385	sporulation resulting in formation of a cellular spore
HUW56_RS10215	COG1316	TRANSCRIPTIONal
HUW56_RS10220	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUW56_RS10225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUW56_RS10230	COG1134	teichoic acid transport
HUW56_RS10235	COG1682	transport, permease protein
HUW56_RS10240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUW56_RS10250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUW56_RS10255	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HUW56_RS10260	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUW56_RS10265	COG4193	domain, Protein
HUW56_RS10270	COG1482	cell wall glycoprotein biosynthetic process
HUW56_RS10275	COG0697	spore germination
HUW56_RS10280	COG0814	amino acid
HUW56_RS10290	COG1215	transferase activity, transferring glycosyl groups
HUW56_RS10295	COG2814	Major facilitator Superfamily
HUW56_RS10300	COG1316	TRANSCRIPTIONal
HUW56_RS10305	COG0561	phosphatase activity
HUW56_RS10310	COG2433	Pfam Transposase IS66
HUW56_RS10315	COG0791	NLP P60 protein
HUW56_RS10325	COG2843	Capsule synthesis protein
HUW56_RS10335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUW56_RS10340	COG0697	spore germination
HUW56_RS10345	COG0814	amino acid
HUW56_RS10355	COG1609	Transcriptional regulator
HUW56_RS10360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUW56_RS10370	COG1129	ABC transporter
HUW56_RS10375	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUW56_RS10380	COG1879	ABC-type sugar transport system periplasmic component
HUW56_RS10385	COG3103	Sh3 type 3 domain protein
HUW56_RS10390	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUW56_RS10395	COG3527	Alpha-acetolactate decarboxylase
HUW56_RS10400	COG0028	Belongs to the TPP enzyme family
HUW56_RS10405	COG0583	DNA-binding transcription factor activity
HUW56_RS10410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUW56_RS10425	COG5337	Spore coat protein CotH
HUW56_RS10435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUW56_RS10445	COG0405	Gamma-glutamyltransferase
HUW56_RS10450	COG1522	sequence-specific DNA binding
HUW56_RS10455	COG2059	Chromate
HUW56_RS10460	COG2059	Chromate
HUW56_RS10470	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUW56_RS10475	COG0583	DNA-binding transcription factor activity
HUW56_RS10500	COG5444	nuclease activity
HUW56_RS10515	COG3878	Protein conserved in bacteria
HUW56_RS10520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUW56_RS10525	COG4464	protein tyrosine phosphatase activity
HUW56_RS10530	COG0489	protein tyrosine kinase activity
HUW56_RS10535	COG3944	biosynthesis protein
HUW56_RS10545	COG4715	Zinc finger, swim domain protein
HUW56_RS10550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUW56_RS10555	COG0561	phosphatase activity
HUW56_RS10560	COG1349	DNA-binding transcription factor activity
HUW56_RS10565	COG0629	single-stranded DNA binding
HUW56_RS10590	COG0457	Tetratricopeptide repeat
HUW56_RS10595	COG4786	Flagellar basal body rod
HUW56_RS10600	COG4786	Flagellar basal body rod
HUW56_RS10605	COG1077	Cell shape determining protein MreB Mrl
HUW56_RS10610	COG1609	Transcriptional regulator
HUW56_RS10615	COG1846	Transcriptional regulator
HUW56_RS10620	COG2814	Major facilitator Superfamily
HUW56_RS10625	COG1953	Uracil, thiamine, allantoin
HUW56_RS10630	COG0477	Major facilitator Superfamily
HUW56_RS10635	COG1335	isochorismatase
HUW56_RS10640	COG0004	ammonium transporteR
HUW56_RS10645	COG0347	Belongs to the P(II) protein family
HUW56_RS10650	COG0772	Belongs to the SEDS family
HUW56_RS10655	COG0671	phosphoesterase, PA-phosphatase related
HUW56_RS10665	COG0739	heme binding
HUW56_RS10670	COG1247	-acetyltransferase
HUW56_RS10685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUW56_RS10695	COG0726	polysaccharide deacetylase
HUW56_RS10705	COG1959	2 iron, 2 sulfur cluster binding
HUW56_RS10720	COG0831	urea catabolic process
HUW56_RS10725	COG3237	CsbD-like
HUW56_RS10730	COG1994	Peptidase M50
HUW56_RS10735	COG0457	Tetratricopeptide repeat
HUW56_RS10745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUW56_RS10755	COG2304	oxidoreductase activity
HUW56_RS10760	COG2304	oxidoreductase activity
HUW56_RS10765	COG2385	sporulation resulting in formation of a cellular spore
HUW56_RS10770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUW56_RS10780	COG4836	Membrane
HUW56_RS10850	COG0698	ribose 5-phosphate isomerase
HUW56_RS10855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUW56_RS10865	COG0009	L-threonylcarbamoyladenylate synthase
HUW56_RS10870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUW56_RS10890	COG2890	protein-(glutamine-N5) methyltransferase activity
HUW56_RS10895	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HUW56_RS10900	COG0346	lactoylglutathione lyase activity
HUW56_RS10905	COG0789	Transcriptional regulator
HUW56_RS10910	COG0679	Auxin Efflux Carrier
HUW56_RS10915	COG0281	malic enzyme
HUW56_RS10930	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HUW56_RS10935	COG1494	fructose-1,6-bisphosphatase
HUW56_RS10940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUW56_RS10950	COG0191	fructose-bisphosphate aldolase activity
HUW56_RS10955	COG2204	response regulator
HUW56_RS10960	COG4821	SIS domain
HUW56_RS10975	COG2181	nitrate reductase activity
HUW56_RS10975	COG0247	lactate metabolic process
HUW56_RS10980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUW56_RS10995	COG1132	(ABC) transporter
HUW56_RS11000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUW56_RS11010	COG2181	nitrate reductase activity
HUW56_RS11015	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HUW56_RS11020	COG1140	nitrate reductase beta subunit
HUW56_RS11025	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HUW56_RS11030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUW56_RS11040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUW56_RS11045	COG2223	nitrite transmembrane transporter activity
HUW56_RS11055	COG4506	Protein conserved in bacteria
HUW56_RS11065	COG3391	amine dehydrogenase activity
HUW56_RS11070	COG3391	amine dehydrogenase activity
HUW56_RS11075	COG0457	Tetratricopeptide repeat
HUW56_RS11085	COG0010	Belongs to the arginase family
HUW56_RS11090	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HUW56_RS11095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUW56_RS11110	COG1994	Peptidase M50
HUW56_RS11115	COG1942	4-Oxalocrotonate Tautomerase
HUW56_RS11120	COG1846	Transcriptional regulator
HUW56_RS11125	COG0531	amino acid
HUW56_RS11130	COG3465	dGTPase activity
HUW56_RS11135	COG1078	dGTPase activity
HUW56_RS11150	COG1695	Transcriptional regulator
HUW56_RS11160	COG1131	(ABC) transporter
HUW56_RS11165	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HUW56_RS11195	COG0583	DNA-binding transcription factor activity
HUW56_RS11200	COG2855	membrane
HUW56_RS11205	COG0280	phosphate acetyltransferase
HUW56_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS11220	COG0436	Aminotransferase
HUW56_RS11250	COG2814	Major facilitator Superfamily
HUW56_RS11255	COG2814	Major facilitator Superfamily
HUW56_RS11260	COG0833	amino acid
HUW56_RS11265	COG4187	Peptidase family M20/M25/M40
HUW56_RS11270	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS11275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUW56_RS11280	COG2205	protein histidine kinase activity
HUW56_RS11285	COG0745	RESPONSE REGULATOR receiver
HUW56_RS11300	COG1131	(ABC) transporter
HUW56_RS11305	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUW56_RS11310	COG1091	dTDP-4-dehydrorhamnose reductase activity
HUW56_RS11315	COG1088	dTDP-glucose 4,6-dehydratase activity
HUW56_RS11320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HUW56_RS11325	COG3980	spore coat polysaccharide biosynthesis protein
HUW56_RS11330	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HUW56_RS11335	COG2089	acid synthase
HUW56_RS11340	COG0456	acetyltransferase
HUW56_RS11345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUW56_RS11350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUW56_RS11355	COG0463	Glycosyl transferase, family 2
HUW56_RS11365	COG2363	Small membrane protein
HUW56_RS11370	COG2233	PERMEase
HUW56_RS11385	COG1216	Glycosyl transferase, family 2
HUW56_RS11400	COG1695	Transcriptional regulator
HUW56_RS11405	COG0351	phosphomethylpyrimidine kinase
HUW56_RS11415	COG1621	beta-fructofuranosidase activity
HUW56_RS11420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS11420	COG1263	PTS System
HUW56_RS11425	COG3711	transcriptional antiterminator
HUW56_RS11435	COG1404	Belongs to the peptidase S8 family
HUW56_RS11440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS11445	COG0778	Nitroreductase
HUW56_RS11450	COG0772	Belongs to the SEDS family
HUW56_RS11455	COG0454	-acetyltransferase
HUW56_RS11475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUW56_RS11480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUW56_RS11485	COG2261	transglycosylase associated protein
HUW56_RS11490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HUW56_RS11495	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUW56_RS11500	COG2246	polysaccharide biosynthetic process
HUW56_RS11505	COG1309	transcriptional regulator
HUW56_RS11525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUW56_RS11530	COG2837	iron assimilation
HUW56_RS11550	COG0583	DNA-binding transcription factor activity
HUW56_RS11560	COG1346	cytolysis
HUW56_RS11565	COG4895	conserved protein (DUF2196)
HUW56_RS11570	COG0789	Transcriptional regulator
HUW56_RS11575	COG5504	Zn-dependent protease
HUW56_RS11580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HUW56_RS11585	COG0346	lactoylglutathione lyase activity
HUW56_RS11590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS11595	COG1404	Belongs to the peptidase S8 family
HUW56_RS11600	COG1442	glycosyl transferase family 8
HUW56_RS11605	COG2357	RelA SpoT domain protein
HUW56_RS11610	COG1575	Belongs to the MenA family. Type 1 subfamily
HUW56_RS11625	COG1696	Membrane protein involved in D-alanine export
HUW56_RS11635	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HUW56_RS11640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS11645	COG1486	melibiose metabolic process
HUW56_RS11650	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUW56_RS11655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS11660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS11665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS11665	COG3711	transcriptional antiterminator
HUW56_RS11675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS11680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS11690	COG0640	Transcriptional regulator
HUW56_RS11695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HUW56_RS11700	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS11705	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUW56_RS11710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS11715	COG2723	6-phospho-beta-galactosidase activity
HUW56_RS11725	COG1482	cell wall glycoprotein biosynthetic process
HUW56_RS11735	COG0753	catalase activity
HUW56_RS11740	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HUW56_RS11745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUW56_RS11765	COG3279	Response regulator of the LytR AlgR family
HUW56_RS11785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUW56_RS11790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HUW56_RS11795	COG4988	ABC transporter
HUW56_RS11800	COG1294	oxidase, subunit
HUW56_RS11805	COG1271	oxidase subunit
HUW56_RS11810	COG3493	citrate carrier protein
HUW56_RS11815	COG0726	polysaccharide deacetylase
HUW56_RS11820	COG3842	ATPase activity
HUW56_RS11825	COG2508	Transcriptional regulator
HUW56_RS11830	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS11840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUW56_RS11855	COG4894	glucomannan catabolic process
HUW56_RS11860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUW56_RS11865	COG0500	methyltransferase
HUW56_RS11870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUW56_RS11885	COG0693	protein deglycase activity
HUW56_RS11885	COG0753	catalase activity
HUW56_RS11890	COG2851	Citrate transporter
HUW56_RS11895	COG2273	Hydrolase Family 16
HUW56_RS11905	COG2270	Major facilitator Superfamily
HUW56_RS11910	COG0513	Belongs to the DEAD box helicase family
HUW56_RS11920	COG0697	spore germination
HUW56_RS11925	COG0589	response to stress
HUW56_RS11985	COG3507	Belongs to the glycosyl hydrolase 43 family
HUW56_RS12010	COG0010	Belongs to the arginase family
HUW56_RS12015	COG0833	amino acid
HUW56_RS12020	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HUW56_RS12025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HUW56_RS12035	COG2390	Transcriptional regulator
HUW56_RS12040	COG0561	phosphatase activity
HUW56_RS12070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUW56_RS12075	COG5294	Protein conserved in bacteria
HUW56_RS12080	COG0577	efflux transmembrane transporter activity
HUW56_RS12085	COG1136	(ABC) transporter
HUW56_RS12090	COG2205	protein histidine kinase activity
HUW56_RS12095	COG0745	RESPONSE REGULATOR receiver
HUW56_RS12100	COG2205	protein histidine kinase activity
HUW56_RS12105	COG0745	RESPONSE REGULATOR receiver
HUW56_RS12135	COG1082	Xylose isomerase domain protein TIM barrel
HUW56_RS12145	COG2814	Major facilitator Superfamily
HUW56_RS12175	COG1349	DNA-binding transcription factor activity
HUW56_RS12180	COG0667	Aldo Keto reductase
HUW56_RS12185	COG2814	Major facilitator Superfamily
HUW56_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS12200	COG2197	response regulator
HUW56_RS12205	COG4585	Histidine kinase
HUW56_RS12210	COG3239	Fatty acid desaturase
HUW56_RS12215	COG1309	transcriptional regulator
HUW56_RS12220	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS12225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUW56_RS12235	COG0640	Transcriptional regulator
HUW56_RS12240	COG2814	Major facilitator Superfamily
HUW56_RS12245	COG1714	RDD family
HUW56_RS12255	COG0450	alkyl hydroperoxide reductase
HUW56_RS12260	COG3634	alkyl hydroperoxide reductase activity
HUW56_RS12265	COG3177	Filamentation induced by cAMP protein fic
HUW56_RS12270	COG1113	amino acid transport
HUW56_RS12280	COG2080	2 iron, 2 sulfur cluster binding
HUW56_RS12295	COG2068	MobA-Related Protein
HUW56_RS12300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUW56_RS12355	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HUW56_RS12360	COG0667	Aldo Keto reductase
HUW56_RS12365	COG0456	acetyltransferase
HUW56_RS12370	COG0457	Tetratricopeptide repeat
HUW56_RS12375	COG0010	Belongs to the arginase family
HUW56_RS12380	COG0833	amino acid
HUW56_RS12385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUW56_RS12390	COG5658	integral membrane protein
HUW56_RS12395	COG0640	Transcriptional regulator
HUW56_RS12400	COG3829	transcription factor binding
HUW56_RS12410	COG0488	(ABC) transporter
HUW56_RS12425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUW56_RS12430	COG3850	Histidine kinase
HUW56_RS12430	COG5002	protein histidine kinase activity
HUW56_RS12435	COG0745	RESPONSE REGULATOR receiver
HUW56_RS12440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUW56_RS12445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HUW56_RS12450	COG4853	Protein conserved in bacteria
HUW56_RS12455	COG4863	YycH protein
HUW56_RS12460	COG5002	protein histidine kinase activity
HUW56_RS12465	COG0745	RESPONSE REGULATOR receiver
HUW56_RS12495	COG0346	lactoylglutathione lyase activity
HUW56_RS12500	COG0305	Participates in initiation and elongation during chromosome replication
HUW56_RS12515	COG3093	addiction module antidote protein HigA
HUW56_RS12520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUW56_RS12525	COG0297	glycogen (starch) synthase activity
HUW56_RS12535	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HUW56_RS12540	COG0438	transferase activity, transferring glycosyl groups
HUW56_RS12560	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HUW56_RS12565	COG4241	membrane
HUW56_RS12575	COG5577	PFAM Coat F domain
HUW56_RS12580	COG1733	regulation of RNA biosynthetic process
HUW56_RS12590	COG0697	spore germination
HUW56_RS12595	COG1621	beta-fructofuranosidase activity
HUW56_RS12600	COG1621	beta-fructofuranosidase activity
HUW56_RS12610	COG2318	DinB family
HUW56_RS12615	COG2211	Major facilitator Superfamily
HUW56_RS12625	COG0778	Nitroreductase
HUW56_RS12630	COG1846	Transcriptional regulator
HUW56_RS12635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS12640	COG1846	Transcriptional regulator
HUW56_RS12645	COG2153	protein acetylation
HUW56_RS12655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUW56_RS12660	COG0583	DNA-binding transcription factor activity
HUW56_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS12675	COG0697	spore germination
HUW56_RS12680	COG1331	Highly conserved protein containing a thioredoxin domain
HUW56_RS12705	COG1331	Highly conserved protein containing a thioredoxin domain
HUW56_RS12710	COG1266	CAAX protease self-immunity
HUW56_RS12715	COG2814	Major facilitator Superfamily
HUW56_RS12715	COG0477	Major facilitator Superfamily
HUW56_RS12720	COG0346	lactoylglutathione lyase activity
HUW56_RS12725	COG1609	Transcriptional regulator
HUW56_RS12730	COG0708	Exodeoxyribonuclease III
HUW56_RS12735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUW56_RS12740	COG2169	Transcriptional regulator
HUW56_RS12750	COG0629	single-stranded DNA binding
HUW56_RS12760	COG0012	GTP binding
HUW56_RS12765	COG0243	molybdopterin cofactor binding
HUW56_RS12770	COG4481	Protein conserved in bacteria
HUW56_RS12775	COG3949	Membrane
HUW56_RS12790	COG1475	DNA binding
HUW56_RS12795	COG1192	Involved in chromosome partitioning
HUW56_RS12820	COG1847	R3H domain protein
HUW56_RS12825	COG0706	membrane insertase activity
HUW56_RS12845	COG0592	DNA-directed DNA polymerase activity
HUW56_RS12850	COG2501	S4 domain
HUW56_RS12865	COG0187	DNA topoisomerase II activity
HUW56_RS12870	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUW56_RS12905	COG0517	IMP dehydrogenase activity
HUW56_RS12905	COG0516	GMP reductase activity
HUW56_RS12910	COG1686	Belongs to the peptidase S11 family
HUW56_RS12930	COG1929	Belongs to the glycerate kinase type-1 family
HUW56_RS12940	COG1428	Deoxynucleoside kinase
HUW56_RS12945	COG1428	Deoxynucleoside kinase
HUW56_RS12950	COG1388	LysM domain
HUW56_RS12950	COG3858	chitin binding
HUW56_RS12955	COG1335	isochorismatase
HUW56_RS12960	COG0590	tRNA wobble adenosine to inosine editing
HUW56_RS12970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUW56_RS12975	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUW56_RS12980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUW56_RS13025	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HUW56_RS13030	COG3853	Toxic anion resistance protein (TelA)
HUW56_RS13035	COG1982	Orn Lys Arg decarboxylase major
HUW56_RS13045	COG3870	Protein conserved in bacteria
HUW56_RS13050	COG1728	Protein conserved in bacteria
HUW56_RS13055	COG0470	DNA polymerase III
HUW56_RS13060	COG1774	PSP1 C-terminal conserved region
HUW56_RS13070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HUW56_RS13080	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HUW56_RS13085	COG2002	toxin-antitoxin pair type II binding
HUW56_RS13090	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUW56_RS13090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUW56_RS13095	COG0084	hydrolase, TatD family'
HUW56_RS13100	COG3583	domain protein
HUW56_RS13100	COG3584	3D domain protein
HUW56_RS13105	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HUW56_RS13110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUW56_RS13120	COG4466	Protein conserved in bacteria
HUW56_RS13135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUW56_RS13140	COG0251	oxidation-reduction process
HUW56_RS13155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUW56_RS13175	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HUW56_RS13180	COG2002	toxin-antitoxin pair type II binding
HUW56_RS13185	COG2244	polysaccharide biosynthetic process
HUW56_RS13190	COG3956	TIGRFAM MazG family protein
HUW56_RS13195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HUW56_RS13210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HUW56_RS13215	COG1098	S1 RNA binding domain
HUW56_RS13230	COG2208	phosphoserine phosphatase activity
HUW56_RS13235	COG2304	oxidoreductase activity
HUW56_RS13240	COG0515	serine threonine protein kinase
HUW56_RS13245	COG0037	tRNA processing
HUW56_RS13255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUW56_RS13270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUW56_RS13275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUW56_RS13280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUW56_RS13285	COG0512	Glutamine amidotransferase of anthranilate synthase
HUW56_RS13290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS13295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUW56_RS13300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUW56_RS13305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HUW56_RS13310	COG1396	sequence-specific DNA binding
HUW56_RS13315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUW56_RS13320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUW56_RS13400	COG4463	regulation of RNA biosynthetic process
HUW56_RS13405	COG3880	PFAM UvrB UvrC protein
HUW56_RS13415	COG0542	response to heat
HUW56_RS13420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUW56_RS13425	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HUW56_RS13430	COG4956	integral membrane protein (PIN domain superfamily)
HUW56_RS13450	COG1045	serine acetyltransferase
HUW56_RS13460	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HUW56_RS13465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUW56_RS13470	COG3688	RNA-binding protein containing a PIN domain
HUW56_RS13475	COG1595	DNA-templated transcription, initiation
HUW56_RS13485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUW56_RS13490	COG0250	Participates in transcription elongation, termination and antitermination
HUW56_RS13515	COG2813	Specifically methylates the guanine in position
HUW56_RS13530	COG1358	cellular component organization or biogenesis
HUW56_RS13555	COG0596	Alpha beta hydrolase
HUW56_RS13650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUW56_RS13665	COG0201	protein transport
HUW56_RS13675	COG0024	Methionine aminopeptidase
HUW56_RS13685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUW56_RS13710	COG1122	ATPase activity
HUW56_RS13715	COG1122	ATPase activity
HUW56_RS13720	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUW56_RS13740	COG2226	methyltransferase
HUW56_RS13745	COG2318	DinB family
HUW56_RS13755	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS13760	COG0489	protein tyrosine kinase activity
HUW56_RS13770	COG2194	sulfuric ester hydrolase activity
HUW56_RS13775	COG0726	polysaccharide deacetylase
HUW56_RS13835	COG0738	Major facilitator superfamily
HUW56_RS13840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS13850	COG1063	alcohol dehydrogenase
HUW56_RS13855	COG0659	secondary active sulfate transmembrane transporter activity
HUW56_RS13860	COG0385	Bile acid
HUW56_RS13865	COG2819	hydrolase of the alpha beta superfamily
HUW56_RS13870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS13875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS13880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUW56_RS13885	COG2207	Transcriptional regulator
HUW56_RS13885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUW56_RS13890	COG3876	Protein conserved in bacteria
HUW56_RS13895	COG1472	Belongs to the glycosyl hydrolase 3 family
HUW56_RS13900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUW56_RS13905	COG1263	PTS System
HUW56_RS13905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS13915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUW56_RS13920	COG1683	Conserved Protein
HUW56_RS13950	COG1595	DNA-templated transcription, initiation
HUW56_RS13955	COG5662	AntiSigma factor
HUW56_RS13960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HUW56_RS13965	COG4856	YbbR-like protein
HUW56_RS13995	COG5002	protein histidine kinase activity
HUW56_RS14000	COG1136	(ABC) transporter
HUW56_RS14005	COG0577	efflux transmembrane transporter activity
HUW56_RS14010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUW56_RS14025	COG1346	cytolysis
HUW56_RS14030	COG1380	Effector of murein hydrolase LrgA
HUW56_RS14035	COG1846	Transcriptional regulator
HUW56_RS14040	COG1113	amino acid transport
HUW56_RS14045	COG1011	Hydrolase
HUW56_RS14050	COG4585	Histidine kinase
HUW56_RS14055	COG2197	response regulator
HUW56_RS14060	COG1131	(ABC) transporter
HUW56_RS14100	COG0531	amino acid
HUW56_RS14105	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HUW56_RS14120	COG0584	glycerophosphoryl diester phosphodiesterase
HUW56_RS14125	COG2271	Major facilitator Superfamily
HUW56_RS14135	COG2368	4-hydroxyphenylacetate
HUW56_RS14145	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS14160	COG1397	ADP-ribosylglycohydrolase
HUW56_RS14165	COG5444	nuclease activity
HUW56_RS14175	COG0371	Dehydrogenase
HUW56_RS14185	COG1183	phosphatidylcholine synthase activity
HUW56_RS14190	COG0586	Pfam SNARE associated Golgi protein
HUW56_RS14195	COG0688	phosphatidylethanolamine metabolic process
HUW56_RS14210	COG1301	dicarboxylic acid transport
HUW56_RS14215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS14220	COG0833	amino acid
HUW56_RS14225	COG2040	homocysteine
HUW56_RS14230	COG1115	amino acid carrier protein
HUW56_RS14235	COG2066	Belongs to the glutaminase family
HUW56_RS14240	COG4191	Histidine kinase
HUW56_RS14245	COG0784	Response regulator, receiver
HUW56_RS14265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUW56_RS14270	COG0778	Nitroreductase
HUW56_RS14275	COG0346	lactoylglutathione lyase activity
HUW56_RS14280	COG2259	Doxx family
HUW56_RS14285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS14300	COG3773	Cell wall hydrolase
HUW56_RS14305	COG3540	Alkaline phosphatase
HUW56_RS14310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUW56_RS14315	COG0805	protein transport
HUW56_RS14325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUW56_RS14330	COG0477	Major facilitator Superfamily
HUW56_RS14335	COG1309	transcriptional regulator
HUW56_RS14340	COG0252	asparaginase activity
HUW56_RS14345	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUW56_RS14350	COG3012	SEC-C Motif Domain Protein
HUW56_RS14350	COG1405	negative regulation of cell septum assembly
HUW56_RS14365	COG1595	DNA-templated transcription, initiation
HUW56_RS14370	COG1595	DNA-templated transcription, initiation
HUW56_RS14375	COG1876	peptidase activity
HUW56_RS14380	COG0457	Tetratricopeptide repeat
HUW56_RS14385	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS14390	COG0366	Alpha amylase catalytic
HUW56_RS14395	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUW56_RS14400	COG1121	(ABC) transporter
HUW56_RS14405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUW56_RS14410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS14415	COG2310	stress, protein
HUW56_RS14420	COG2310	stress, protein
HUW56_RS14425	COG2310	stress, protein
HUW56_RS14430	COG0861	Integral membrane protein TerC family
HUW56_RS14440	COG3853	Toxic anion resistance protein (TelA)
HUW56_RS14445	COG0477	Major facilitator Superfamily
HUW56_RS14450	COG4175	Glycine betaine
HUW56_RS14450	COG0517	IMP dehydrogenase activity
HUW56_RS14455	COG4176	ABC-type proline glycine betaine transport system permease component
HUW56_RS14460	COG2113	Glycine betaine
HUW56_RS14465	COG1473	amidohydrolase
HUW56_RS14470	COG1288	antiporter activity
HUW56_RS14490	COG2814	Major facilitator Superfamily
HUW56_RS14495	COG1846	Transcriptional regulator
HUW56_RS14500	COG1280	lysine exporter protein (LysE YggA)
HUW56_RS14505	COG3403	YqcI/YcgG family
HUW56_RS14510	COG1113	amino acid transport
HUW56_RS14515	COG3665	Urea carboxylase-associated protein
HUW56_RS14530	COG1660	Displays ATPase and GTPase activities
HUW56_RS14535	COG1082	Xylose isomerase domain protein TIM barrel
HUW56_RS14540	COG2271	Major facilitator Superfamily
HUW56_RS14545	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUW56_RS14550	COG3458	cephalosporin-C deacetylase activity
HUW56_RS14555	COG3541	Predicted nucleotidyltransferase
HUW56_RS14560	COG0506	proline dehydrogenase activity
HUW56_RS14565	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS14570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUW56_RS14575	COG2508	Transcriptional regulator
HUW56_RS14585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUW56_RS14585	COG1587	Uroporphyrinogen-III synthase
HUW56_RS14590	COG2146	nitrite reductase [NAD(P)H] activity
HUW56_RS14595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUW56_RS14600	COG0243	molybdopterin cofactor binding
HUW56_RS14605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUW56_RS14610	COG2223	nitrite transmembrane transporter activity
HUW56_RS14615	COG0523	cobalamin synthesis protein
HUW56_RS14620	COG1063	alcohol dehydrogenase
HUW56_RS14625	COG1714	RDD family
HUW56_RS14635	COG2723	6-phospho-beta-galactosidase activity
HUW56_RS14650	COG3209	COG3209 Rhs family protein
HUW56_RS14655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HUW56_RS14660	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HUW56_RS14665	COG1733	regulation of RNA biosynthetic process
HUW56_RS14670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS14675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS14680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUW56_RS14685	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HUW56_RS14700	COG2364	Membrane
HUW56_RS14705	COG1126	abc transporter atp-binding protein
HUW56_RS14710	COG0765	amino acid transport
HUW56_RS14720	COG0583	DNA-binding transcription factor activity
HUW56_RS14725	COG0163	prenyltransferase activity
HUW56_RS14730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HUW56_RS14745	COG3104	oligopeptide transport
HUW56_RS14750	COG5434	Belongs to the glycosyl hydrolase 28 family
HUW56_RS14760	COG0697	spore germination
HUW56_RS14770	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HUW56_RS14775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUW56_RS14780	COG0456	acetyltransferase
HUW56_RS14785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUW56_RS14790	COG0765	amino acid transport
HUW56_RS14795	COG1126	abc transporter atp-binding protein
HUW56_RS14800	COG1473	amidohydrolase
HUW56_RS14805	COG2079	MmgE PrpD family protein
HUW56_RS14810	COG1136	(ABC) transporter
HUW56_RS14815	COG0577	efflux transmembrane transporter activity
HUW56_RS14820	COG0745	RESPONSE REGULATOR receiver
HUW56_RS14825	COG3850	Histidine kinase
HUW56_RS14825	COG5002	protein histidine kinase activity
HUW56_RS14830	COG0457	Tetratricopeptide repeat
HUW56_RS14845	COG0527	aspartate kinase activity
HUW56_RS14850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUW56_RS14855	COG4605	iron ion homeostasis
HUW56_RS14860	COG4604	ABC transporter, ATP-binding protein
HUW56_RS14865	COG4607	ABC-type enterochelin transport system periplasmic component
HUW56_RS14870	COG2814	Major facilitator Superfamily
HUW56_RS14875	COG1309	transcriptional regulator
HUW56_RS14880	COG0778	Nitroreductase
HUW56_RS14885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUW56_RS14890	COG0640	Transcriptional regulator
HUW56_RS14895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS14900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS14905	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS14910	COG4975	Glucose uptake
HUW56_RS14915	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS14920	COG4549	nuclear export factor GLE1
HUW56_RS14925	COG1276	copper resistance
HUW56_RS14925	COG2372	response to copper ion
HUW56_RS14930	COG1349	DNA-binding transcription factor activity
HUW56_RS14940	COG2213	PTS system mannitol-specific
HUW56_RS14945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUW56_RS14955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HUW56_RS14965	COG0561	phosphatase activity
HUW56_RS14975	COG1914	H( )-stimulated, divalent metal cation uptake system
HUW56_RS14985	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUW56_RS14990	COG1984	allophanate hydrolase subunit 2
HUW56_RS14995	COG1414	Transcriptional regulator
HUW56_RS15000	COG2755	lipolytic protein G-D-S-L family
HUW56_RS15010	COG2329	Antibiotic biosynthesis monooxygenase
HUW56_RS15015	COG0768	penicillin binding
HUW56_RS15020	COG4989	oxidoreductase activity
HUW56_RS15025	COG3711	transcriptional antiterminator
HUW56_RS15030	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS15035	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS15040	COG1917	Cupin 2, conserved barrel domain protein
HUW56_RS15045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUW56_RS15050	COG3871	stress protein (general stress protein 26)
HUW56_RS15060	COG2814	Major facilitator Superfamily
HUW56_RS15065	COG1522	sequence-specific DNA binding
HUW56_RS15070	COG0551	DNA topoisomerase type I activity
HUW56_RS15070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUW56_RS15075	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HUW56_RS15080	COG3706	GGDEF domain
HUW56_RS15085	COG5298	Protein conserved in bacteria
HUW56_RS15090	COG1215	transferase activity, transferring glycosyl groups
HUW56_RS15100	COG0531	amino acid
HUW56_RS15110	COG0028	Belongs to the TPP enzyme family
HUW56_RS15135	COG0457	Tetratricopeptide repeat
HUW56_RS15155	COG1914	H( )-stimulated, divalent metal cation uptake system
HUW56_RS15165	COG4876	unkown
HUW56_RS15175	COG2076	Multidrug Resistance protein
HUW56_RS15180	COG2217	Heavy metal translocating P-type atpase
HUW56_RS15185	COG3729	General stress protein
HUW56_RS15190	COG0662	Cupin 2, conserved barrel domain protein
HUW56_RS15195	COG2329	Antibiotic biosynthesis monooxygenase
HUW56_RS15200	COG3546	catalase activity
HUW56_RS15205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HUW56_RS15210	COG3290	protein histidine kinase activity
HUW56_RS15215	COG4565	transcriptional regulatory protein
HUW56_RS15220	COG1301	dicarboxylic acid transport
HUW56_RS15225	COG0628	permease
HUW56_RS15230	COG1131	(ABC) transporter
HUW56_RS15235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HUW56_RS15245	COG1960	acyl-CoA dehydrogenase activity
HUW56_RS15260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HUW56_RS15265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUW56_RS15275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUW56_RS15280	COG0513	Belongs to the DEAD box helicase family
HUW56_RS15285	COG3402	PFAM membrane-flanked domain
HUW56_RS15290	COG3428	Bacterial PH domain
HUW56_RS15295	COG0705	Rhomboid family
HUW56_RS15305	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HUW56_RS15310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUW56_RS15315	COG0864	Transcriptional regulator
HUW56_RS15320	COG2337	Toxic component of a toxin-antitoxin (TA) module
HUW56_RS15325	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS15330	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS15335	COG2172	sigma factor antagonist activity
HUW56_RS15340	COG2208	phosphoserine phosphatase activity
HUW56_RS15345	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS15355	COG1191	sigma factor activity
HUW56_RS15360	COG2208	phosphoserine phosphatase activity
HUW56_RS15365	COG2183	response to ionizing radiation
HUW56_RS15430	COG5444	nuclease activity
HUW56_RS15435	COG0457	Tetratricopeptide repeat
HUW56_RS15450	COG0477	Major facilitator Superfamily
HUW56_RS15455	COG1846	Transcriptional regulator
HUW56_RS15465	COG2030	dehydratase
HUW56_RS15480	COG1959	2 iron, 2 sulfur cluster binding
HUW56_RS15485	COG2910	NAD(P)H-binding
HUW56_RS15500	COG1278	Cold shock
HUW56_RS15505	COG1329	Transcriptional regulator
HUW56_RS15510	COG1937	Protein conserved in bacteria
HUW56_RS15515	COG2210	Belongs to the sulfur carrier protein TusA family
HUW56_RS15525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUW56_RS15525	COG0425	Belongs to the sulfur carrier protein TusA family
HUW56_RS15530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS15530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUW56_RS15535	COG0425	Belongs to the sulfur carrier protein TusA family
HUW56_RS15540	COG0730	response to heat
HUW56_RS15545	COG1794	racemase activity, acting on amino acids and derivatives
HUW56_RS15560	COG3621	Patatin-like phospholipase
HUW56_RS15570	COG0662	Cupin 2, conserved barrel domain protein
HUW56_RS15585	COG0277	FAD linked oxidase domain protein
HUW56_RS15605	COG0662	Cupin 2, conserved barrel domain protein
HUW56_RS15610	COG2318	DinB family
HUW56_RS15645	COG1064	alcohol dehydrogenase
HUW56_RS15650	COG0789	Transcriptional regulator
HUW56_RS15660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS15670	COG2814	Major facilitator Superfamily
HUW56_RS15675	COG1309	transcriptional regulator
HUW56_RS15680	COG0697	spore germination
HUW56_RS15685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS15690	COG5577	PFAM Coat F domain
HUW56_RS15700	COG1063	alcohol dehydrogenase
HUW56_RS15705	COG5577	PFAM Coat F domain
HUW56_RS15715	COG4585	Histidine kinase
HUW56_RS15720	COG2197	response regulator
HUW56_RS15725	COG2409	Drug exporters of the RND superfamily
HUW56_RS15730	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUW56_RS15740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUW56_RS15745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS15755	COG2814	Major facilitator Superfamily
HUW56_RS15760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUW56_RS15770	COG0730	response to heat
HUW56_RS15775	COG0456	acetyltransferase
HUW56_RS15780	COG0789	Transcriptional regulator
HUW56_RS15780	COG4978	Transcriptional regulator
HUW56_RS15785	COG0697	spore germination
HUW56_RS15790	COG1051	belongs to the nudix hydrolase family
HUW56_RS15795	COG2226	methyltransferase
HUW56_RS15800	COG0473	3-isopropylmalate dehydrogenase activity
HUW56_RS15805	COG1802	Transcriptional regulator
HUW56_RS15810	COG1819	glycosyl
HUW56_RS15825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUW56_RS15835	COG1388	LysM domain
HUW56_RS15840	COG2814	Major facilitator Superfamily
HUW56_RS15845	COG2188	Transcriptional regulator
HUW56_RS15850	COG2186	Transcriptional regulator
HUW56_RS15855	COG2807	transmembrane transport
HUW56_RS15860	COG2076	Multidrug Resistance protein
HUW56_RS15865	COG2076	Multidrug Resistance protein
HUW56_RS15870	COG1309	transcriptional regulator
HUW56_RS15875	COG0531	amino acid
HUW56_RS15885	COG3832	glyoxalase III activity
HUW56_RS15890	COG0604	alcohol dehydrogenase
HUW56_RS15895	COG2814	Major facilitator Superfamily
HUW56_RS15935	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HUW56_RS15940	COG0802	atpase or kinase
HUW56_RS15945	COG1214	PFAM Peptidase M22, glycoprotease
HUW56_RS15950	COG0456	acetyltransferase
HUW56_RS15955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUW56_RS15960	COG0488	(ABC) transporter
HUW56_RS15975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUW56_RS15980	COG0805	protein transport
HUW56_RS15990	COG1266	CAAX protease self-immunity
HUW56_RS16030	COG0457	Tetratricopeptide repeat
HUW56_RS16035	COG1063	alcohol dehydrogenase
HUW56_RS16040	COG2211	Major facilitator Superfamily
HUW56_RS16045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUW56_RS16055	COG1842	Phage shock protein A
HUW56_RS16060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUW56_RS16065	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUW56_RS16070	COG4260	virion core protein, lumpy skin disease virus
HUW56_RS16075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUW56_RS16075	COG2755	lipolytic protein G-D-S-L family
HUW56_RS16085	COG1595	DNA-templated transcription, initiation
HUW56_RS16090	COG1063	alcohol dehydrogenase
HUW56_RS16095	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HUW56_RS16100	COG0823	Involved in the tonB-independent uptake of proteins
HUW56_RS16110	COG2132	Multicopper oxidase
HUW56_RS16115	COG1113	amino acid transport
HUW56_RS16120	COG0714	Associated with various cellular activities
HUW56_RS16125	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HUW56_RS16130	COG1305	Transglutaminase-like
HUW56_RS16155	COG2252	PERMEase
HUW56_RS16160	COG3064	Membrane
HUW56_RS16180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUW56_RS16185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUW56_RS16190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUW56_RS16195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUW56_RS16200	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUW56_RS16215	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HUW56_RS16225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HUW56_RS16230	COG0138	bifunctional purine biosynthesis protein purh
HUW56_RS16235	COG0151	Belongs to the GarS family
HUW56_RS16245	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUW56_RS16250	COG1470	cell adhesion involved in biofilm formation
HUW56_RS16255	COG4496	protein, YerC YecD
HUW56_RS16260	COG0069	glutamate synthase activity
HUW56_RS16270	COG0210	DNA helicase
HUW56_RS16280	COG4851	CamS sex pheromone cAM373 precursor
HUW56_RS16285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUW56_RS16290	COG1285	pathogenesis
HUW56_RS16295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUW56_RS16315	COG1309	transcriptional regulator
HUW56_RS16320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUW56_RS16325	COG1597	lipid kinase activity
HUW56_RS16330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUW56_RS16340	COG1131	(ABC) transporter
HUW56_RS16380	COG5444	nuclease activity
HUW56_RS16410	COG3546	catalase activity
HUW56_RS16415	COG0454	-acetyltransferase
HUW56_RS16425	COG2323	membrane
HUW56_RS16430	COG2329	Antibiotic biosynthesis monooxygenase
HUW56_RS16435	COG0346	lactoylglutathione lyase activity
HUW56_RS16440	COG1366	Belongs to the anti-sigma-factor antagonist family
HUW56_RS16445	COG5583	Uncharacterized small protein (DUF2292)
HUW56_RS16450	COG0196	riboflavin kinase activity
HUW56_RS16455	COG0670	Belongs to the BI1 family
HUW56_RS16460	COG1846	Transcriptional regulator
HUW56_RS16465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUW56_RS16475	COG2124	cytochrome p450
HUW56_RS16475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HUW56_RS16480	COG1368	sulfuric ester hydrolase activity
HUW56_RS16485	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUW56_RS16490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUW56_RS16495	COG1442	glycosyl transferase family 8
HUW56_RS16500	COG1216	Glycosyl transferase, family 2
HUW56_RS16505	COG1442	glycosyl transferase family 8
HUW56_RS16510	COG2223	nitrite transmembrane transporter activity
HUW56_RS16515	COG0531	amino acid
HUW56_RS16520	COG1012	belongs to the aldehyde dehydrogenase family
HUW56_RS16525	COG0840	transmembrane signaling receptor activity
HUW56_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS16535	COG0457	Tetratricopeptide repeat
HUW56_RS16535	COG0463	Glycosyl transferase, family 2
HUW56_RS16540	COG0488	(ABC) transporter
HUW56_RS16545	COG0789	Transcriptional regulator
HUW56_RS16550	COG2814	Major facilitator Superfamily
HUW56_RS16555	COG0488	(ABC) transporter
HUW56_RS16560	COG0513	Belongs to the DEAD box helicase family
HUW56_RS16565	COG0456	acetyltransferase
HUW56_RS16570	COG2130	NADP-dependent
HUW56_RS16585	COG3866	Pectate lyase
HUW56_RS16590	COG0471	metal ion transport
HUW56_RS16610	COG3290	protein histidine kinase activity
HUW56_RS16615	COG4565	transcriptional regulatory protein
HUW56_RS16620	COG3181	Tripartite tricarboxylate transporter family receptor
HUW56_RS16625	COG2851	Citrate transporter
HUW56_RS16630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUW56_RS16635	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HUW56_RS16645	COG2258	MOSC domain
HUW56_RS16665	COG0024	Methionine aminopeptidase
HUW56_RS16670	COG1263	PTS System
HUW56_RS16670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS16680	COG1368	sulfuric ester hydrolase activity
HUW56_RS16690	COG0071	Belongs to the small heat shock protein (HSP20) family
HUW56_RS16705	COG1263	PTS System
HUW56_RS16705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS16710	COG0366	Alpha amylase catalytic
HUW56_RS16715	COG2188	Transcriptional regulator
HUW56_RS16720	COG0778	Nitroreductase
HUW56_RS16735	COG0737	Belongs to the 5'-nucleotidase family
HUW56_RS16740	COG0693	protein deglycase activity
HUW56_RS16745	COG1609	Transcriptional regulator
HUW56_RS16760	COG2814	Major facilitator Superfamily
HUW56_RS16770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUW56_RS16775	COG4980	gas vesicle protein
HUW56_RS16780	COG1295	ribonuclease BN
HUW56_RS16785	COG0477	Major facilitator Superfamily
HUW56_RS16790	COG0387	Pfam Sodium calcium exchanger
HUW56_RS16800	COG0668	transmembrane transport
HUW56_RS16805	COG0535	radical SAM domain protein
HUW56_RS16815	COG0726	polysaccharide deacetylase
HUW56_RS16835	COG0745	RESPONSE REGULATOR receiver
HUW56_RS16840	COG2205	protein histidine kinase activity
HUW56_RS16845	COG2084	Dehydrogenase
HUW56_RS16855	COG0598	Magnesium transport protein CorA
HUW56_RS16860	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HUW56_RS16865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUW56_RS16875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HUW56_RS16880	COG4637	Psort location Cytoplasmic, score
HUW56_RS16885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUW56_RS16890	COG0022	dehydrogenase e1 component
HUW56_RS16895	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUW56_RS16900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUW56_RS16905	COG3284	Transcriptional regulator
HUW56_RS16915	COG1486	melibiose metabolic process
HUW56_RS16920	COG1737	Transcriptional regulator
HUW56_RS16925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUW56_RS16925	COG1263	PTS System
HUW56_RS16935	COG1132	(ABC) transporter
HUW56_RS16940	COG1132	(ABC) transporter
HUW56_RS16945	COG2259	Doxx family
HUW56_RS16950	COG2514	catechol 2,3-dioxygenase activity
HUW56_RS16960	COG1695	Transcriptional regulator
HUW56_RS16965	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUW56_RS16970	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HUW56_RS16975	COG0574	Belongs to the PEP-utilizing enzyme family
HUW56_RS16975	COG3848	Pyruvate phosphate dikinase
HUW56_RS16980	COG2732	(Barnase) inhibitor
HUW56_RS16985	COG2318	DinB family
HUW56_RS16990	COG2814	Major facilitator Superfamily
HUW56_RS16995	COG1846	Transcriptional regulator
HUW56_RS17000	COG0392	lysyltransferase activity
HUW56_RS17000	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUW56_RS17005	COG0384	phenazine biosynthesis protein PhzF
HUW56_RS17010	COG0778	Nitroreductase
HUW56_RS17025	COG1090	epimerase
HUW56_RS17040	COG2814	Major facilitator Superfamily
HUW56_RS17050	COG3591	Belongs to the peptidase S1B family
HUW56_RS17065	COG3103	Sh3 type 3 domain protein
HUW56_RS17070	COG5658	integral membrane protein
HUW56_RS17075	COG0596	Alpha beta hydrolase
HUW56_RS17080	COG0463	Glycosyl transferase, family 2
HUW56_RS17085	COG4485	Bacterial membrane protein, YfhO
HUW56_RS17090	COG1988	membrane-bound metal-dependent
HUW56_RS17095	COG1194	a g-specific adenine glycosylase
HUW56_RS17105	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS17125	COG1132	(ABC) transporter
HUW56_RS17130	COG4129	membrane
HUW56_RS17140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HUW56_RS17145	COG0735	belongs to the Fur family
HUW56_RS17260	COG3340	Belongs to the peptidase S51 family
HUW56_RS17270	COG0277	FAD linked oxidase domain protein
HUW56_RS17280	COG0747	negative chemotaxis
HUW56_RS17285	COG0601	transmembrane transport
HUW56_RS17290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUW56_RS17295	COG0444	Belongs to the ABC transporter superfamily
HUW56_RS17300	COG4608	Belongs to the ABC transporter superfamily
HUW56_RS17305	COG0753	catalase activity
HUW56_RS17315	COG1116	anion transmembrane transporter activity
HUW56_RS17320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUW56_RS17325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUW56_RS17345	COG1476	TRANSCRIPTIONal
HUW56_RS17355	COG3382	B3 4 domain protein
HUW56_RS17360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HUW56_RS17370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUW56_RS17375	COG0789	Transcriptional regulator
HUW56_RS17380	COG1664	Polymer-forming cytoskeletal
HUW56_RS17385	COG1664	Polymer-forming cytoskeletal
HUW56_RS17390	COG2766	serine protein kinase
HUW56_RS17400	COG1846	Transcriptional regulator
HUW56_RS17405	COG1566	PFAM secretion protein HlyD family protein
HUW56_RS17410	COG2814	Major facilitator Superfamily
HUW56_RS17415	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUW56_RS17430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HUW56_RS17435	COG1278	Cold shock
HUW56_RS17440	COG1464	Belongs to the NlpA lipoprotein family
HUW56_RS17445	COG3706	GGDEF domain
HUW56_RS17450	COG1823	symporter activity
HUW56_RS17470	COG5577	PFAM Coat F domain
HUW56_RS17475	COG0737	Belongs to the 5'-nucleotidase family
HUW56_RS17475	COG1525	nuclease
HUW56_RS17475	COG4085	toxin activity
HUW56_RS17480	COG3764	Sortase (surface protein transpeptidase)
HUW56_RS17485	COG0564	pseudouridine synthase activity
HUW56_RS17495	COG0517	IMP dehydrogenase activity
HUW56_RS17500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUW56_RS17505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUW56_RS17505	COG3153	acetyltransferase
HUW56_RS17510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUW56_RS17515	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HUW56_RS17520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUW56_RS17530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUW56_RS17535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUW56_RS17540	COG2203	Gaf domain
HUW56_RS17540	COG4585	Histidine kinase
HUW56_RS17545	COG2197	response regulator
HUW56_RS17550	COG0431	NADPH-dependent FMN reductase
HUW56_RS17565	COG1388	LysM domain
HUW56_RS17565	COG0791	NLP P60 protein
HUW56_RS17570	COG1959	2 iron, 2 sulfur cluster binding
HUW56_RS17575	COG0668	transmembrane transport
HUW56_RS17580	COG2719	SpoVR family
HUW56_RS17585	COG1785	Belongs to the alkaline phosphatase family
HUW56_RS17590	COG1388	LysM domain
HUW56_RS17590	COG0791	NLP P60 protein
HUW56_RS17595	COG0583	DNA-binding transcription factor activity
HUW56_RS17600	COG0372	Belongs to the citrate synthase family
HUW56_RS17605	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS17610	COG0531	amino acid
HUW56_RS17615	COG0733	neurotransmitter:sodium symporter activity
HUW56_RS17630	COG1595	DNA-templated transcription, initiation
HUW56_RS17635	COG0204	Acyl-transferase
HUW56_RS17640	COG1253	flavin adenine dinucleotide binding
HUW56_RS17645	COG0789	Transcriptional regulator
HUW56_RS17650	COG0436	Aminotransferase
HUW56_RS17655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUW56_RS17660	COG1253	flavin adenine dinucleotide binding
HUW56_RS17665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUW56_RS17670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUW56_RS17675	COG0584	glycerophosphoryl diester phosphodiesterase
HUW56_RS17685	COG0668	transmembrane transport
HUW56_RS17690	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUW56_RS17695	COG0726	polysaccharide deacetylase
HUW56_RS17700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUW56_RS17705	COG3226	Transcriptional regulator
HUW56_RS17715	COG0589	response to stress
HUW56_RS17720	COG1132	(ABC) transporter
HUW56_RS17725	COG1132	(ABC) transporter
HUW56_RS17730	COG0702	epimerase
HUW56_RS17745	COG0189	ligase activity
HUW56_RS17750	COG0189	ligase activity
HUW56_RS17765	COG4335	DNA alkylation repair
HUW56_RS17770	COG0561	phosphatase activity
HUW56_RS17775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUW56_RS17785	COG0475	glutathione-regulated potassium exporter activity
HUW56_RS17790	COG0490	domain, Protein
HUW56_RS17800	COG1024	Enoyl-CoA hydratase
HUW56_RS17810	COG4152	abc transporter atp-binding protein
HUW56_RS17815	COG1668	transmembrane transport
HUW56_RS17820	COG0420	3'-5' exonuclease activity
HUW56_RS17825	COG4717	serine-type aminopeptidase activity
HUW56_RS17840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HUW56_RS17875	COG4980	gas vesicle protein
HUW56_RS17890	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUW56_RS17895	COG0537	adenosine 5'-monophosphoramidase activity
HUW56_RS17900	COG1131	(ABC) transporter
HUW56_RS17905	COG4473	ABC transporter
HUW56_RS17915	COG1473	amidohydrolase
HUW56_RS17920	COG3069	C4-dicarboxylate transmembrane transporter activity
HUW56_RS17925	COG2329	Antibiotic biosynthesis monooxygenase
HUW56_RS17930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUW56_RS17950	COG1309	transcriptional regulator
HUW56_RS17955	COG1511	domain protein
HUW56_RS17960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUW56_RS17970	COG1363	Peptidase, m42
HUW56_RS17975	COG1301	dicarboxylic acid transport
HUW56_RS17985	COG1234	tRNA 3'-trailer cleavage
HUW56_RS17990	COG0095	Lipoate-protein ligase
HUW56_RS17995	COG0702	epimerase
HUW56_RS18000	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS18010	COG0501	Belongs to the peptidase M48B family
HUW56_RS18015	COG1404	Belongs to the peptidase S8 family
HUW56_RS18020	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HUW56_RS18025	COG0406	alpha-ribazole phosphatase activity
HUW56_RS18030	COG0183	Belongs to the thiolase family
HUW56_RS18035	COG0318	PFAM AMP-dependent synthetase and ligase
HUW56_RS18040	COG1268	BioY protein
HUW56_RS18045	COG0840	transmembrane signaling receptor activity
HUW56_RS18050	COG0723	plastoquinol--plastocyanin reductase activity
HUW56_RS18050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUW56_RS18055	COG1028	Short-chain dehydrogenase reductase Sdr
HUW56_RS18065	COG4903	ComK protein
HUW56_RS18075	COG5646	InterPro IPR014922
HUW56_RS18095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUW56_RS18110	COG0398	Pfam SNARE associated Golgi protein
HUW56_RS18115	COG0681	Belongs to the peptidase S26 family
HUW56_RS18120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUW56_RS18125	COG1846	Transcriptional regulator
HUW56_RS18130	COG3180	Ammonia monooxygenase
HUW56_RS18135	COG2814	Major facilitator Superfamily
HUW56_RS18145	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HUW56_RS18150	COG2323	membrane
HUW56_RS18165	COG0420	3'-5' exonuclease activity
HUW56_RS18170	COG0419	ATPase involved in DNA repair
HUW56_RS18175	COG1403	HNH endonuclease
HUW56_RS18215	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUW56_RS18230	COG0367	asparagine synthase
HUW56_RS18235	COG1562	ergosterol biosynthetic process
HUW56_RS18240	COG0534	Mate efflux family protein
HUW56_RS18245	COG2207	Transcriptional regulator
HUW56_RS18245	COG1917	Cupin 2, conserved barrel domain protein
HUW56_RS18255	COG2318	DinB family
HUW56_RS18260	COG1279	arginine transmembrane transporter activity
HUW56_RS18265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUW56_RS18270	COG1357	PFAM Pentapeptide repeats (8 copies)
HUW56_RS18275	COG2153	protein acetylation
HUW56_RS18280	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUW56_RS18280	COG0646	methionine synthase
HUW56_RS18290	COG2996	Protein conserved in bacteria
HUW56_RS18300	COG0840	transmembrane signaling receptor activity
HUW56_RS18305	COG2124	cytochrome p450
HUW56_RS18315	COG1307	EDD domain protein, DegV family
HUW56_RS18320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HUW56_RS18340	COG0561	phosphatase activity
HUW56_RS18345	COG1073	alpha beta
HUW56_RS18350	COG2151	metal-sulfur cluster biosynthetic enzyme
HUW56_RS18360	COG0277	FAD linked oxidase domain protein
HUW56_RS18365	COG2271	Major facilitator Superfamily
HUW56_RS18375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUW56_RS18385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUW56_RS18390	COG0505	Belongs to the CarA family
HUW56_RS18395	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUW56_RS18400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUW56_RS18415	COG2267	carboxylic ester hydrolase activity
HUW56_RS18425	COG1744	ABC transporter substrate-binding protein PnrA-like
HUW56_RS18440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUW56_RS18445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUW56_RS18450	COG5504	Zn-dependent protease
HUW56_RS18455	COG0444	Belongs to the ABC transporter superfamily
HUW56_RS18460	COG4608	Belongs to the ABC transporter superfamily
HUW56_RS18470	COG0601	transmembrane transport
HUW56_RS18475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUW56_RS18485	COG0180	Tryptophanyl-tRNA synthetase
HUW56_RS18490	COG4166	transmembrane transport
HUW56_RS18495	COG0601	transmembrane transport
HUW56_RS18500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUW56_RS18505	COG0444	Belongs to the ABC transporter superfamily
HUW56_RS18510	COG4608	Belongs to the ABC transporter superfamily
HUW56_RS18520	COG0456	acetyltransferase
HUW56_RS18525	COG1393	Belongs to the ArsC family
HUW56_RS18530	COG0861	Integral membrane protein TerC family
HUW56_RS18540	COG4862	establishment of competence for transformation
HUW56_RS18545	COG4469	Competence protein
HUW56_RS18550	COG1164	Oligoendopeptidase f
HUW56_RS18565	COG2346	COG2346, Truncated hemoglobins
HUW56_RS18570	COG0741	lytic transglycosylase activity
HUW56_RS18575	COG4116	CYTH
HUW56_RS18585	COG2357	RelA SpoT domain protein
HUW56_RS18590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUW56_RS18595	COG0564	pseudouridine synthase activity
HUW56_RS18605	COG0475	glutathione-regulated potassium exporter activity
HUW56_RS18605	COG0569	domain protein
HUW56_RS18610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HUW56_RS18615	COG0352	thiamine-phosphate diphosphorylase activity
HUW56_RS18620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUW56_RS18625	COG2104	thiamine diphosphate biosynthetic process
HUW56_RS18635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUW56_RS18640	COG0351	phosphomethylpyrimidine kinase
HUW56_RS18645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUW56_RS18700	COG0210	DNA helicase
HUW56_RS18720	COG1131	(ABC) transporter
HUW56_RS18730	COG2153	protein acetylation
HUW56_RS18740	COG2382	esterase
HUW56_RS18745	COG0626	cystathionine gamma-synthase activity
HUW56_RS18750	COG0626	cystathionine gamma-synthase activity
HUW56_RS18780	COG5444	nuclease activity
HUW56_RS18790	COG0346	lactoylglutathione lyase activity
HUW56_RS18795	COG2367	Beta-lactamase
HUW56_RS18800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HUW56_RS18805	COG0477	Major facilitator Superfamily
HUW56_RS18810	COG1846	Transcriptional regulator
HUW56_RS18820	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HUW56_RS18825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUW56_RS18830	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUW56_RS18835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS18835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HUW56_RS18840	COG1447	Phosphotransferase system cellobiose-specific component IIA
HUW56_RS18850	COG1349	DNA-binding transcription factor activity
HUW56_RS18870	COG1285	pathogenesis
HUW56_RS18885	COG2205	protein histidine kinase activity
HUW56_RS18895	COG3383	formate dehydrogenase (NAD+) activity
HUW56_RS18900	COG2427	Protein of unknown function (DUF1641)
HUW56_RS18905	COG2124	cytochrome p450
HUW56_RS18910	COG1819	glycosyl
HUW56_RS18920	COG1587	Uroporphyrinogen-III synthase
HUW56_RS18925	COG0390	transport system, permease component
HUW56_RS18930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUW56_RS18935	COG0697	spore germination
HUW56_RS18940	COG4297	protein containing double-stranded beta helix domain
HUW56_RS18950	COG1252	NADH dehydrogenase
HUW56_RS18960	COG2211	Major facilitator Superfamily
HUW56_RS18965	COG1609	Transcriptional regulator
HUW56_RS18970	COG0246	Mannitol dehydrogenase
HUW56_RS18975	COG2721	sulfolactate sulfo-lyase activity
HUW56_RS18980	COG0745	RESPONSE REGULATOR receiver
HUW56_RS18985	COG2205	protein histidine kinase activity
HUW56_RS18985	COG2770	Histidine kinase
HUW56_RS19005	COG4585	Histidine kinase
HUW56_RS19010	COG2197	response regulator
HUW56_RS19045	COG0730	response to heat
HUW56_RS19050	COG2318	DinB family
HUW56_RS19055	COG0457	Tetratricopeptide repeat
HUW56_RS19065	COG5632	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS19065	COG1388	LysM domain
HUW56_RS19065	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS19075	COG4195	phage-related replication protein
HUW56_RS19080	COG2856	Zn peptidase
HUW56_RS19085	COG1396	sequence-specific DNA binding
HUW56_RS19090	COG1522	sequence-specific DNA binding
HUW56_RS19095	COG1484	DNA-dependent DNA replication
HUW56_RS19115	COG1595	DNA-templated transcription, initiation
HUW56_RS19120	COG5484	DNA packaging
HUW56_RS19120	COG3728	DNA packaging
HUW56_RS19125	COG1783	phage Terminase large subunit
HUW56_RS19130	COG5518	Phage portal protein
HUW56_RS19135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HUW56_RS19140	COG4653	Phage capsid family
HUW56_RS19190	COG5412	phage tail tape measure protein
HUW56_RS19190	COG3953	SLT domain
HUW56_RS19190	COG5412	phage tail tape measure protein
HUW56_RS19190	COG3953	SLT domain
HUW56_RS19190	COG3953	SLT domain
HUW56_RS19190	COG5412	phage tail tape measure protein
HUW56_RS19195	COG1652	LysM domain
HUW56_RS19200	COG4193	domain, Protein
HUW56_RS19210	COG3628	GPW Gp25 family protein
HUW56_RS19215	COG3299	homolog of phage Mu protein gp47
HUW56_RS19220	COG3778	Protein conserved in bacteria
HUW56_RS19260	COG5632	N-Acetylmuramoyl-L-alanine amidase
HUW56_RS19260	COG3409	Peptidoglycan-binding domain 1 protein
HUW56_RS19275	COG0306	phosphate transporter
HUW56_RS19280	COG1392	Phosphate transport regulator
HUW56_RS19285	COG0531	amino acid
HUW56_RS19290	COG0346	lactoylglutathione lyase activity
HUW56_RS19295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUW56_RS19300	COG0463	Glycosyl transferase, family 2
HUW56_RS19310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUW56_RS19315	COG0477	Major facilitator Superfamily
HUW56_RS19320	COG2362	D-Aminopeptidase
HUW56_RS19325	COG0601	transmembrane transport
HUW56_RS19330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components