locus-tag	class	description
EXW45_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW45_RS00015	COG2501	S4 domain
EXW45_RS00025	COG0187	DNA topoisomerase II activity
EXW45_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW45_RS00065	COG0516	GMP reductase activity
EXW45_RS00065	COG0517	IMP dehydrogenase activity
EXW45_RS00070	COG1686	Belongs to the peptidase S11 family
EXW45_RS00100	COG1428	Deoxynucleoside kinase
EXW45_RS00105	COG1428	Deoxynucleoside kinase
EXW45_RS00110	COG1335	isochorismatase
EXW45_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW45_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW45_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW45_RS00190	COG0470	DNA polymerase III
EXW45_RS00195	COG1774	PSP1 C-terminal conserved region
EXW45_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW45_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW45_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW45_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW45_RS00230	COG0084	hydrolase, TatD family'
EXW45_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW45_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW45_RS00250	COG4466	Protein conserved in bacteria
EXW45_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW45_RS00270	COG0251	oxidation-reduction process
EXW45_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW45_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW45_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW45_RS00310	COG2244	polysaccharide biosynthetic process
EXW45_RS00315	COG3956	TIGRFAM MazG family protein
EXW45_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW45_RS00340	COG1098	S1 RNA binding domain
EXW45_RS00355	COG2208	phosphoserine phosphatase activity
EXW45_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW45_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW45_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW45_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW45_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW45_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW45_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW45_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW45_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW45_RS00420	COG1396	sequence-specific DNA binding
EXW45_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW45_RS00515	COG3880	PFAM UvrB UvrC protein
EXW45_RS00525	COG0542	response to heat
EXW45_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW45_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW45_RS00560	COG1045	serine acetyltransferase
EXW45_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW45_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW45_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW45_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW45_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW45_RS00620	COG0222	ribosome binding
EXW45_RS00625	COG2813	Specifically methylates the guanine in position
EXW45_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW45_RS00640	COG1358	cellular component organization or biogenesis
EXW45_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW45_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW45_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW45_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW45_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW45_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW45_RS00760	COG1841	ribosomal large subunit assembly
EXW45_RS00770	COG0201	protein transport
EXW45_RS00780	COG0024	Methionine aminopeptidase
EXW45_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW45_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW45_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW45_RS00855	COG0489	protein tyrosine kinase activity
EXW45_RS00865	COG2194	sulfuric ester hydrolase activity
EXW45_RS00870	COG0726	polysaccharide deacetylase
EXW45_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW45_RS00955	COG4856	YbbR-like protein
EXW45_RS00975	COG4946	Tricorn protease homolog
EXW45_RS00975	COG1506	peptidase
EXW45_RS00975	COG0823	Involved in the tonB-independent uptake of proteins
EXW45_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS01005	COG2011	ABC-type metal ion transport system permease component
EXW45_RS01015	COG1464	Belongs to the NlpA lipoprotein family
EXW45_RS01020	COG0604	alcohol dehydrogenase
EXW45_RS01030	COG0277	FAD linked oxidase domain protein
EXW45_RS01035	COG2271	Major facilitator Superfamily
EXW45_RS01045	COG2814	Major facilitator Superfamily
EXW45_RS01060	COG0601	transmembrane transport
EXW45_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW45_RS01070	COG0444	Belongs to the ABC transporter superfamily
EXW45_RS01075	COG4608	Belongs to the ABC transporter superfamily
EXW45_RS01080	COG4166	transmembrane transport
EXW45_RS01090	COG2207	Transcriptional regulator
EXW45_RS01105	COG4166	transmembrane transport
EXW45_RS01110	COG4166	transmembrane transport
EXW45_RS01115	COG0656	L-ascorbic acid biosynthetic process
EXW45_RS01130	COG4149	molybdate abc transporter
EXW45_RS01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW45_RS01140	COG1910	domain protein
EXW45_RS01160	COG0697	spore germination
EXW45_RS01175	COG0204	Acyl-transferase
EXW45_RS01185	COG1609	Transcriptional regulator
EXW45_RS01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS01205	COG0084	hydrolase, TatD family'
EXW45_RS01215	COG5298	Protein conserved in bacteria
EXW45_RS01240	COG0488	(ABC) transporter
EXW45_RS01250	COG0747	negative chemotaxis
EXW45_RS01255	COG0747	negative chemotaxis
EXW45_RS01260	COG0601	transmembrane transport
EXW45_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW45_RS01270	COG0444	Belongs to the ABC transporter superfamily
EXW45_RS01275	COG4608	Belongs to the ABC transporter superfamily
EXW45_RS01280	COG0561	phosphatase activity
EXW45_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW45_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW45_RS01325	COG0531	amino acid
EXW45_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW45_RS01350	COG4294	response to UV
EXW45_RS01355	COG0705	Rhomboid family
EXW45_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW45_RS01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW45_RS01375	COG0864	Transcriptional regulator
EXW45_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW45_RS01385	COG2183	response to ionizing radiation
EXW45_RS01485	COG0802	atpase or kinase
EXW45_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW45_RS01495	COG0456	acetyltransferase
EXW45_RS01505	COG0488	(ABC) transporter
EXW45_RS01520	COG1266	CAAX protease self-immunity
EXW45_RS01530	COG0459	protein refolding
EXW45_RS01540	COG2252	PERMEase
EXW45_RS01550	COG5002	protein histidine kinase activity
EXW45_RS01575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW45_RS01605	COG2226	methyltransferase
EXW45_RS01615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW45_RS01625	COG1215	transferase activity, transferring glycosyl groups
EXW45_RS01665	COG2205	protein histidine kinase activity
EXW45_RS01670	COG0745	RESPONSE REGULATOR receiver
EXW45_RS01690	COG0697	spore germination
EXW45_RS01710	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW45_RS01715	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW45_RS01720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW45_RS01730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW45_RS01745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW45_RS01755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW45_RS01765	COG0151	Belongs to the GarS family
EXW45_RS01790	COG0210	DNA helicase
EXW45_RS01800	COG4851	CamS sex pheromone cAM373 precursor
EXW45_RS01820	COG1335	isochorismatase
EXW45_RS01830	COG2011	ABC-type metal ion transport system permease component
EXW45_RS01835	COG1464	Belongs to the NlpA lipoprotein family
EXW45_RS01850	COG0003	Pfam Anion-transporting ATPase
EXW45_RS01855	COG1846	Transcriptional regulator
EXW45_RS01860	COG4682	membrane
EXW45_RS01880	COG1597	lipid kinase activity
EXW45_RS01885	COG0546	phosphoglycolate phosphatase activity
EXW45_RS01890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW45_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS01905	COG2076	Multidrug Resistance protein
EXW45_RS01910	COG2309	aminopeptidase activity
EXW45_RS01925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS01935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW45_RS01940	COG5002	protein histidine kinase activity
EXW45_RS01945	COG4807	Protein conserved in bacteria
EXW45_RS01970	COG1757	Na H antiporter
EXW45_RS01975	COG1473	amidohydrolase
EXW45_RS01990	COG0450	alkyl hydroperoxide reductase
EXW45_RS02000	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW45_RS02010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS02020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS02025	COG0492	ferredoxin-NADP+ reductase activity
EXW45_RS02035	COG0166	Belongs to the GPI family
EXW45_RS02080	COG3541	Predicted nucleotidyltransferase
EXW45_RS02085	COG2814	Major facilitator Superfamily
EXW45_RS02090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW45_RS02090	COG0723	plastoquinol--plastocyanin reductase activity
EXW45_RS02100	COG0765	amino acid transport
EXW45_RS02105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS02110	COG1126	abc transporter atp-binding protein
EXW45_RS02115	COG0840	transmembrane signaling receptor activity
EXW45_RS02120	COG0277	FAD linked oxidase domain protein
EXW45_RS02125	COG0366	Alpha amylase catalytic
EXW45_RS02130	COG2190	(PTS) system
EXW45_RS02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW45_RS02130	COG1263	PTS System
EXW45_RS02165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW45_RS02180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW45_RS02190	COG1116	anion transmembrane transporter activity
EXW45_RS02195	COG0488	(ABC) transporter
EXW45_RS02245	COG2270	Major facilitator Superfamily
EXW45_RS02270	COG4193	domain, Protein
EXW45_RS02280	COG2310	stress, protein
EXW45_RS02285	COG2310	stress, protein
EXW45_RS02290	COG2310	stress, protein
EXW45_RS02295	COG0861	Integral membrane protein TerC family
EXW45_RS02305	COG3853	Toxic anion resistance protein (TelA)
EXW45_RS02320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW45_RS02330	COG1295	ribonuclease BN
EXW45_RS02335	COG2217	Heavy metal translocating P-type atpase
EXW45_RS02340	COG0697	spore germination
EXW45_RS02360	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS02375	COG3871	stress protein (general stress protein 26)
EXW45_RS02380	COG0387	Pfam Sodium calcium exchanger
EXW45_RS02390	COG0535	radical SAM domain protein
EXW45_RS02410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW45_RS02430	COG3829	transcription factor binding
EXW45_RS02440	COG0833	amino acid
EXW45_RS02445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW45_RS02475	COG1263	PTS System
EXW45_RS02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW45_RS02480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW45_RS02500	COG0463	Glycosyl transferase, family 2
EXW45_RS02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW45_RS02510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW45_RS02515	COG0463	Glycosyl transferase, family 2
EXW45_RS02525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW45_RS02545	COG1228	amidohydrolase
EXW45_RS02550	COG1090	epimerase
EXW45_RS02580	COG1988	membrane-bound metal-dependent
EXW45_RS02585	COG1194	a g-specific adenine glycosylase
EXW45_RS02610	COG1132	(ABC) transporter
EXW45_RS02615	COG4129	membrane
EXW45_RS02620	COG0070	glutamate synthase
EXW45_RS02620	COG0067	glutamate synthase
EXW45_RS02620	COG0069	glutamate synthase activity
EXW45_RS02630	COG4555	ABC transporter
EXW45_RS02650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW45_RS02655	COG0735	belongs to the Fur family
EXW45_RS02770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW45_RS02775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW45_RS02785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EXW45_RS02795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW45_RS02800	COG5001	Diguanylate cyclase
EXW45_RS02800	COG1716	ATPase activity
EXW45_RS02805	COG2766	serine protein kinase
EXW45_RS02825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW45_RS02835	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW45_RS02840	COG2268	Band 7 protein
EXW45_RS02850	COG3290	protein histidine kinase activity
EXW45_RS02855	COG4565	transcriptional regulatory protein
EXW45_RS02860	COG2851	Citrate transporter
EXW45_RS02880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW45_RS02885	COG0745	RESPONSE REGULATOR receiver
EXW45_RS02890	COG5002	protein histidine kinase activity
EXW45_RS02900	COG4990	cell redox homeostasis
EXW45_RS02910	COG3290	protein histidine kinase activity
EXW45_RS02915	COG4565	transcriptional regulatory protein
EXW45_RS02920	COG3493	citrate carrier protein
EXW45_RS02925	COG0281	malic enzyme
EXW45_RS02935	COG0697	spore germination
EXW45_RS02940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS02950	COG5002	protein histidine kinase activity
EXW45_RS02955	COG0745	RESPONSE REGULATOR receiver
EXW45_RS02960	COG0454	-acetyltransferase
EXW45_RS02960	COG0456	acetyltransferase
EXW45_RS02965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW45_RS02970	COG3383	formate dehydrogenase (NAD+) activity
EXW45_RS02975	COG2427	Protein of unknown function (DUF1641)
EXW45_RS02990	COG0531	amino acid
EXW45_RS02995	COG0640	Transcriptional regulator
EXW45_RS03000	COG2217	Heavy metal translocating P-type atpase
EXW45_RS03005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW45_RS03020	COG3227	Zinc metalloprotease (Elastase)
EXW45_RS03040	COG2720	vancomycin resistance protein
EXW45_RS03045	COG1316	TRANSCRIPTIONal
EXW45_RS03050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS03055	COG0346	lactoylglutathione lyase activity
EXW45_RS03060	COG1253	flavin adenine dinucleotide binding
EXW45_RS03065	COG1027	Aspartate ammonia-lyase
EXW45_RS03075	COG1620	l-lactate permease
EXW45_RS03090	COG3104	oligopeptide transport
EXW45_RS03095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS03100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS03105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS03115	COG2226	methyltransferase
EXW45_RS03120	COG0156	8-amino-7-oxononanoate synthase activity
EXW45_RS03125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW45_RS03130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW45_RS03140	COG4548	von Willebrand factor, type A
EXW45_RS03145	COG0714	Associated with various cellular activities
EXW45_RS03150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS03165	COG0531	amino acid
EXW45_RS03170	COG2188	Transcriptional regulator
EXW45_RS03175	COG1263	PTS System
EXW45_RS03175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW45_RS03180	COG0366	Alpha amylase catalytic
EXW45_RS03195	COG0697	spore germination
EXW45_RS03200	COG4585	Histidine kinase
EXW45_RS03205	COG2197	response regulator
EXW45_RS03210	COG1404	Belongs to the peptidase S8 family
EXW45_RS03225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW45_RS03230	COG1115	amino acid carrier protein
EXW45_RS03235	COG1126	abc transporter atp-binding protein
EXW45_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS03245	COG0765	amino acid transport
EXW45_RS03250	COG0765	amino acid transport
EXW45_RS03255	COG0833	amino acid
EXW45_RS03280	COG2378	regulation of single-species biofilm formation
EXW45_RS03285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW45_RS03295	COG5002	protein histidine kinase activity
EXW45_RS03310	COG0659	secondary active sulfate transmembrane transporter activity
EXW45_RS03325	COG0747	negative chemotaxis
EXW45_RS03330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW45_RS03335	COG0601	transmembrane transport
EXW45_RS03340	COG4608	Belongs to the ABC transporter superfamily
EXW45_RS03350	COG2271	Major facilitator Superfamily
EXW45_RS03355	COG1846	Transcriptional regulator
EXW45_RS03360	COG0477	Major facilitator Superfamily
EXW45_RS03365	COG1609	Transcriptional regulator
EXW45_RS03370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW45_RS03385	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW45_RS03390	COG1879	ABC-type sugar transport system periplasmic component
EXW45_RS03405	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW45_RS03415	COG1063	alcohol dehydrogenase
EXW45_RS03430	COG3568	Endonuclease Exonuclease Phosphatase
EXW45_RS03465	COG0840	transmembrane signaling receptor activity
EXW45_RS03470	COG3584	3D domain protein
EXW45_RS03470	COG1388	LysM domain
EXW45_RS03475	COG1476	TRANSCRIPTIONal
EXW45_RS03495	COG3104	oligopeptide transport
EXW45_RS03500	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS03515	COG1113	amino acid transport
EXW45_RS03520	COG2252	PERMEase
EXW45_RS03540	COG2153	protein acetylation
EXW45_RS03550	COG0475	glutathione-regulated potassium exporter activity
EXW45_RS03550	COG0569	domain protein
EXW45_RS03560	COG1845	cytochrome c oxidase, subunit III
EXW45_RS03565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW45_RS03570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW45_RS03575	COG0833	amino acid
EXW45_RS03580	COG4990	cell redox homeostasis
EXW45_RS03595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW45_RS03600	COG0697	spore germination
EXW45_RS03605	COG0531	amino acid
EXW45_RS03620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW45_RS03625	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW45_RS03630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW45_RS03630	COG1918	ferrous iron import across plasma membrane
EXW45_RS03635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW45_RS03640	COG0573	inorganic phosphate transmembrane transporter activity
EXW45_RS03645	COG0581	inorganic phosphate transmembrane transporter activity
EXW45_RS03655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW45_RS03775	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW45_RS03795	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW45_RS03800	COG1116	anion transmembrane transporter activity
EXW45_RS03805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW45_RS03810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW45_RS03815	COG0352	thiamine-phosphate diphosphorylase activity
EXW45_RS03820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW45_RS03825	COG2104	thiamine diphosphate biosynthetic process
EXW45_RS03835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW45_RS03840	COG0351	phosphomethylpyrimidine kinase
EXW45_RS03880	COG2205	protein histidine kinase activity
EXW45_RS03885	COG2814	Major facilitator Superfamily
EXW45_RS03890	COG1846	Transcriptional regulator
EXW45_RS03900	COG2252	PERMEase
EXW45_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS03965	COG0778	Nitroreductase
EXW45_RS03970	COG2719	SpoVR family
EXW45_RS03995	COG0446	pyridine nucleotide-disulphide oxidoreductase
EXW45_RS04000	COG1937	Protein conserved in bacteria
EXW45_RS04005	COG0425	Belongs to the sulfur carrier protein TusA family
EXW45_RS04005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS04010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS04010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS04015	COG0425	Belongs to the sulfur carrier protein TusA family
EXW45_RS04020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS04020	COG0425	Belongs to the sulfur carrier protein TusA family
EXW45_RS04025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS04030	COG2210	Belongs to the sulfur carrier protein TusA family
EXW45_RS04035	COG0730	response to heat
EXW45_RS04045	COG1316	TRANSCRIPTIONal
EXW45_RS04050	COG0604	alcohol dehydrogenase
EXW45_RS04055	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW45_RS04060	COG2814	Major facilitator Superfamily
EXW45_RS04070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW45_RS04070	COG3711	transcriptional antiterminator
EXW45_RS04075	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW45_RS04080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW45_RS04100	COG3584	3D domain protein
EXW45_RS04100	COG1388	LysM domain
EXW45_RS04105	COG0577	efflux transmembrane transporter activity
EXW45_RS04110	COG1136	(ABC) transporter
EXW45_RS04120	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW45_RS04135	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS04140	COG3546	catalase activity
EXW45_RS04175	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS04210	COG0531	amino acid
EXW45_RS04215	COG0475	glutathione-regulated potassium exporter activity
EXW45_RS04225	COG1737	Transcriptional regulator
EXW45_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW45_RS04235	COG1263	PTS System
EXW45_RS04245	COG2259	Doxx family
EXW45_RS04260	COG0697	spore germination
EXW45_RS04265	COG1522	sequence-specific DNA binding
EXW45_RS04290	COG2076	Multidrug Resistance protein
EXW45_RS04295	COG1309	transcriptional regulator
EXW45_RS04300	COG2814	Major facilitator Superfamily
EXW45_RS04305	COG1733	regulation of RNA biosynthetic process
EXW45_RS04315	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW45_RS04325	COG4533	DNA binding
EXW45_RS04330	COG2211	Major facilitator Superfamily
EXW45_RS04340	COG0693	protein deglycase activity
EXW45_RS04350	COG0531	amino acid
EXW45_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS04360	COG1132	(ABC) transporter
EXW45_RS04365	COG1132	(ABC) transporter
EXW45_RS04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS04375	COG0765	amino acid transport
EXW45_RS04380	COG1126	abc transporter atp-binding protein
EXW45_RS04395	COG0189	ligase activity
EXW45_RS04410	COG3679	Belongs to the UPF0342 family
EXW45_RS04425	COG0028	Belongs to the TPP enzyme family
EXW45_RS04430	COG3527	Alpha-acetolactate decarboxylase
EXW45_RS04440	COG0561	phosphatase activity
EXW45_RS04450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW45_RS04470	COG0659	secondary active sulfate transmembrane transporter activity
EXW45_RS04485	COG1024	Enoyl-CoA hydratase
EXW45_RS04500	COG1363	Peptidase, m42
EXW45_RS04615	COG0601	transmembrane transport
EXW45_RS04620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW45_RS04625	COG0444	Belongs to the ABC transporter superfamily
EXW45_RS04630	COG4608	Belongs to the ABC transporter superfamily
EXW45_RS04680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS04700	COG0457	Tetratricopeptide repeat
EXW45_RS04735	COG0477	Major facilitator Superfamily
EXW45_RS04740	COG3290	protein histidine kinase activity
EXW45_RS04745	COG4565	transcriptional regulatory protein
EXW45_RS04750	COG3181	Tripartite tricarboxylate transporter family receptor
EXW45_RS04790	COG0789	Transcriptional regulator
EXW45_RS04790	COG4978	Transcriptional regulator
EXW45_RS04830	COG0305	Participates in initiation and elongation during chromosome replication
EXW45_RS04865	COG0477	Major facilitator Superfamily
EXW45_RS04900	COG0577	efflux transmembrane transporter activity
EXW45_RS04905	COG1136	(ABC) transporter
EXW45_RS04945	COG2274	protein secretion by the type I secretion system
EXW45_RS04995	COG1183	phosphatidylcholine synthase activity
EXW45_RS05010	COG2814	Major facilitator Superfamily
EXW45_RS05015	COG0640	Transcriptional regulator
EXW45_RS05040	COG2376	Dihydroxyacetone kinase
EXW45_RS05050	COG2376	Dihydroxyacetone kinase
EXW45_RS05060	COG1959	2 iron, 2 sulfur cluster binding
EXW45_RS05090	COG0457	Tetratricopeptide repeat
EXW45_RS05105	COG2770	Histidine kinase
EXW45_RS05105	COG3437	response regulator, receiver
EXW45_RS05135	COG0482	sulfurtransferase activity
EXW45_RS05185	COG3237	CsbD-like
EXW45_RS05210	COG1191	sigma factor activity
EXW45_RS05220	COG2208	phosphoserine phosphatase activity
EXW45_RS05225	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW45_RS05270	COG4585	Histidine kinase
EXW45_RS05275	COG2197	response regulator
EXW45_RS05305	COG0420	3'-5' exonuclease activity
EXW45_RS05310	COG4717	serine-type aminopeptidase activity
EXW45_RS05325	COG1280	lysine exporter protein (LysE YggA)
EXW45_RS05330	COG0346	lactoylglutathione lyase activity
EXW45_RS05335	COG0346	lactoylglutathione lyase activity
EXW45_RS05350	COG2267	carboxylic ester hydrolase activity
EXW45_RS05450	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW45_RS05455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW45_RS05465	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW45_RS05470	COG1695	Transcriptional regulator
EXW45_RS05490	COG1595	DNA-templated transcription, initiation
EXW45_RS05515	COG0477	Major facilitator Superfamily
EXW45_RS05520	COG0477	Major facilitator Superfamily
EXW45_RS05535	COG3973	AAA domain
EXW45_RS05540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW45_RS05565	COG0537	adenosine 5'-monophosphoramidase activity
EXW45_RS05570	COG1131	(ABC) transporter
EXW45_RS05575	COG4473	ABC transporter
EXW45_RS05600	COG1309	transcriptional regulator
EXW45_RS05610	COG3402	PFAM membrane-flanked domain
EXW45_RS05615	COG3428	Bacterial PH domain
EXW45_RS05655	COG3402	PFAM membrane-flanked domain
EXW45_RS05660	COG3428	Bacterial PH domain
EXW45_RS05665	COG2329	Antibiotic biosynthesis monooxygenase
EXW45_RS05670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW45_RS05685	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW45_RS05710	COG1309	transcriptional regulator
EXW45_RS05715	COG1511	domain protein
EXW45_RS05740	COG2318	DinB family
EXW45_RS05745	COG2378	regulation of single-species biofilm formation
EXW45_RS05750	COG1609	Transcriptional regulator
EXW45_RS05760	COG1234	tRNA 3'-trailer cleavage
EXW45_RS05765	COG0095	Lipoate-protein ligase
EXW45_RS05775	COG0318	PFAM AMP-dependent synthetase and ligase
EXW45_RS05785	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW45_RS05795	COG4208	sulfate ABC transporter
EXW45_RS05835	COG1408	metallophosphoesterase
EXW45_RS05840	COG1078	dGTPase activity
EXW45_RS05850	COG1595	DNA-templated transcription, initiation
EXW45_RS05855	COG3708	Transcriptional regulator
EXW45_RS05855	COG2207	Transcriptional regulator
EXW45_RS05860	COG2205	protein histidine kinase activity
EXW45_RS05865	COG0745	RESPONSE REGULATOR receiver
EXW45_RS05895	COG0501	Belongs to the peptidase M48B family
EXW45_RS05900	COG0840	transmembrane signaling receptor activity
EXW45_RS05905	COG0697	spore germination
EXW45_RS05920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW45_RS05925	COG2224	Isocitrate lyase
EXW45_RS05935	COG1278	Cold shock
EXW45_RS05950	COG0398	Pfam SNARE associated Golgi protein
EXW45_RS06010	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW45_RS06035	COG0367	asparagine synthase
EXW45_RS06045	COG0753	catalase activity
EXW45_RS06050	COG0004	ammonium transporteR
EXW45_RS06070	COG2996	Protein conserved in bacteria
EXW45_RS06075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW45_RS06085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS06100	COG0561	phosphatase activity
EXW45_RS06120	COG2267	carboxylic ester hydrolase activity
EXW45_RS06135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW45_RS06140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW45_RS06145	COG5504	Zn-dependent protease
EXW45_RS06155	COG0180	Tryptophanyl-tRNA synthetase
EXW45_RS06165	COG4166	transmembrane transport
EXW45_RS06170	COG0601	transmembrane transport
EXW45_RS06175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW45_RS06180	COG0444	Belongs to the ABC transporter superfamily
EXW45_RS06185	COG4608	Belongs to the ABC transporter superfamily
EXW45_RS06190	COG0534	Mate efflux family protein
EXW45_RS06195	COG4166	transmembrane transport
EXW45_RS06210	COG0861	Integral membrane protein TerC family
EXW45_RS06215	COG4862	establishment of competence for transformation
EXW45_RS06220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS06230	COG1164	Oligoendopeptidase f
EXW45_RS06245	COG2346	COG2346, Truncated hemoglobins
EXW45_RS06250	COG4116	CYTH
EXW45_RS06260	COG2357	RelA SpoT domain protein
EXW45_RS06270	COG0564	pseudouridine synthase activity
EXW45_RS06285	COG0772	Belongs to the SEDS family
EXW45_RS06290	COG1216	Glycosyl transferase, family 2
EXW45_RS06300	COG4122	O-methyltransferase activity
EXW45_RS06310	COG0463	Glycosyl transferase, family 2
EXW45_RS06310	COG0457	Tetratricopeptide repeat
EXW45_RS06330	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW45_RS06345	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW45_RS06385	COG0210	DNA helicase
EXW45_RS06390	COG2153	protein acetylation
EXW45_RS06400	COG2382	esterase
EXW45_RS06415	COG5492	domain, Protein
EXW45_RS06420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW45_RS06430	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW45_RS06430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW45_RS06450	COG0133	tryptophan synthase activity
EXW45_RS06465	COG1620	l-lactate permease
EXW45_RS06470	COG5634	Uncharacterized conserved protein (DUF2278)
EXW45_RS06510	COG2226	methyltransferase
EXW45_RS06535	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW45_RS06545	COG1476	TRANSCRIPTIONal
EXW45_RS06585	COG2226	methyltransferase
EXW45_RS06595	COG1686	Belongs to the peptidase S11 family
EXW45_RS06600	COG0681	Belongs to the peptidase S26 family
EXW45_RS06635	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS06645	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW45_RS06650	COG1177	transmembrane transport
EXW45_RS06655	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW45_RS06665	COG2409	Drug exporters of the RND superfamily
EXW45_RS06675	COG0564	pseudouridine synthase activity
EXW45_RS06685	COG2340	Cysteine-rich secretory protein family
EXW45_RS06690	COG0247	lactate metabolic process
EXW45_RS06695	COG0277	FAD linked oxidase domain protein
EXW45_RS06700	COG3835	regulator
EXW45_RS06710	COG0745	RESPONSE REGULATOR receiver
EXW45_RS06715	COG5002	protein histidine kinase activity
EXW45_RS06720	COG2186	Transcriptional regulator
EXW45_RS06735	COG1556	Lactate utilization protein
EXW45_RS06740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW45_RS06750	COG2116	formate transmembrane transporter activity
EXW45_RS06755	COG0861	Integral membrane protein TerC family
EXW45_RS06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW45_RS06770	COG2030	dehydratase
EXW45_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS06795	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW45_RS06805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW45_RS06820	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW45_RS06825	COG3842	ATPase activity
EXW45_RS06850	COG1349	DNA-binding transcription factor activity
EXW45_RS06860	COG0235	Class ii aldolase
EXW45_RS06870	COG2861	carbohydrate metabolic process
EXW45_RS06880	COG3852	Histidine kinase
EXW45_RS06885	COG1846	Transcriptional regulator
EXW45_RS06895	COG2318	DinB family
EXW45_RS06900	COG5002	protein histidine kinase activity
EXW45_RS06910	COG0720	synthase
EXW45_RS06925	COG4873	Protein conserved in bacteria
EXW45_RS06955	COG1780	Probably involved in ribonucleotide reductase function
EXW45_RS06970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW45_RS06975	COG1725	Transcriptional regulator
EXW45_RS06980	COG1131	(ABC) transporter
EXW45_RS06990	COG1131	(ABC) transporter
EXW45_RS06995	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW45_RS07010	COG1522	sequence-specific DNA binding
EXW45_RS07025	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW45_RS07030	COG2070	2-Nitropropane dioxygenase
EXW45_RS07035	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW45_RS07045	COG1696	Membrane protein involved in D-alanine export
EXW45_RS07070	COG0716	FMN binding
EXW45_RS07085	COG3173	Aminoglycoside phosphotransferase
EXW45_RS07105	COG0534	Mate efflux family protein
EXW45_RS07125	COG1846	Transcriptional regulator
EXW45_RS07135	COG1301	dicarboxylic acid transport
EXW45_RS07140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW45_RS07145	COG4709	membrane
EXW45_RS07150	COG3874	Sporulation protein YtfJ
EXW45_RS07170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW45_RS07175	COG0028	Belongs to the TPP enzyme family
EXW45_RS07180	COG0440	acetolactate synthase activity
EXW45_RS07255	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW45_RS07270	COG1183	phosphatidylcholine synthase activity
EXW45_RS07275	COG1368	sulfuric ester hydrolase activity
EXW45_RS07285	COG0019	diaminopimelate decarboxylase activity
EXW45_RS07305	COG0529	Catalyzes the synthesis of activated sulfate
EXW45_RS07310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW45_RS07330	COG1648	precorrin-2 dehydrogenase activity
EXW45_RS07335	COG0733	neurotransmitter:sodium symporter activity
EXW45_RS07360	COG1757	Na H antiporter
EXW45_RS07375	COG4758	membrane
EXW45_RS07380	COG4585	Histidine kinase
EXW45_RS07385	COG2197	response regulator
EXW45_RS07395	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS07405	COG2226	methyltransferase
EXW45_RS07445	COG0730	response to heat
EXW45_RS07450	COG0306	phosphate transporter
EXW45_RS07455	COG1392	Phosphate transport regulator
EXW45_RS07460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW45_RS07475	COG3852	Histidine kinase
EXW45_RS07480	COG1801	Protein of unknown function DUF72
EXW45_RS07490	COG0582	viral genome integration into host DNA
EXW45_RS07495	COG5002	protein histidine kinase activity
EXW45_RS07510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW45_RS07510	COG0392	lysyltransferase activity
EXW45_RS07525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW45_RS07530	COG1686	Belongs to the peptidase S11 family
EXW45_RS07535	COG2715	membrane protein required for spore maturation
EXW45_RS07540	COG0700	Nucleoside recognition
EXW45_RS07545	COG1187	pseudouridine synthase activity
EXW45_RS07555	COG1333	cytochrome c biogenesis protein
EXW45_RS07560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW45_RS07565	COG0745	RESPONSE REGULATOR receiver
EXW45_RS07570	COG5002	protein histidine kinase activity
EXW45_RS07575	COG2096	Adenosyltransferase
EXW45_RS07580	COG4942	peptidase
EXW45_RS07590	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW45_RS07595	COG1141	Ferredoxin
EXW45_RS07605	COG0514	ATP-dependent DNA helicase (RecQ)
EXW45_RS07610	COG1266	CAAX protease self-immunity
EXW45_RS07620	COG1408	metallophosphoesterase
EXW45_RS07630	COG4862	establishment of competence for transformation
EXW45_RS07635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW45_RS07655	COG0492	ferredoxin-NADP+ reductase activity
EXW45_RS07660	COG0252	asparaginase activity
EXW45_RS07710	COG1160	GTP binding
EXW45_RS07735	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW45_RS07750	COG0142	geranyltranstransferase activity
EXW45_RS07760	COG0142	geranyltranstransferase activity
EXW45_RS07785	COG0457	Tetratricopeptide repeat
EXW45_RS07805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW45_RS07810	COG2010	Cytochrome c
EXW45_RS07810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW45_RS07815	COG4347	Protein of unknown function (DUF1405)
EXW45_RS07830	COG2738	Putative neutral zinc metallopeptidase
EXW45_RS07840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS07845	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW45_RS07865	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS07900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW45_RS07900	COG1199	ATP-dependent helicase activity
EXW45_RS07920	COG3935	DnaD domain protein
EXW45_RS07925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW45_RS07935	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW45_RS07935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW45_RS07995	COG0116	Belongs to the methyltransferase superfamily
EXW45_RS08005	COG1199	ATP-dependent helicase activity
EXW45_RS08010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW45_RS08020	COG0024	Methionine aminopeptidase
EXW45_RS08030	COG2233	PERMEase
EXW45_RS08035	COG2311	Membrane
EXW45_RS08040	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW45_RS08050	COG0456	acetyltransferase
EXW45_RS08105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW45_RS08120	COG0454	-acetyltransferase
EXW45_RS08140	COG0328	RNA-DNA hybrid ribonuclease activity
EXW45_RS08175	COG3403	YqcI/YcgG family
EXW45_RS08180	COG1280	lysine exporter protein (LysE YggA)
EXW45_RS08195	COG3162	membrane
EXW45_RS08200	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW45_RS08205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW45_RS08215	COG0475	glutathione-regulated potassium exporter activity
EXW45_RS08220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW45_RS08225	COG4978	Transcriptional regulator
EXW45_RS08225	COG0789	Transcriptional regulator
EXW45_RS08235	COG2323	membrane
EXW45_RS08240	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW45_RS08270	COG2814	Major facilitator Superfamily
EXW45_RS08290	COG1923	regulation of RNA biosynthetic process
EXW45_RS08300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW45_RS08305	COG1360	Flagellar Motor Protein
EXW45_RS08310	COG2201	protein-glutamate methylesterase activity
EXW45_RS08315	COG2198	Histidine kinase
EXW45_RS08315	COG0643	Histidine kinase
EXW45_RS08320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW45_RS08320	COG1776	CheC inhibitor of MCP methylation
EXW45_RS08335	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW45_RS08355	COG1256	bacterial-type flagellum assembly
EXW45_RS08360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW45_RS08380	COG1815	bacterial-type flagellum-dependent cell motility
EXW45_RS08385	COG1558	bacterial-type flagellum-dependent cell motility
EXW45_RS08395	COG1766	The M ring may be actively involved in energy transduction
EXW45_RS08400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW45_RS08410	COG1157	protein secretion by the type III secretion system
EXW45_RS08445	COG0835	chemotaxis
EXW45_RS08445	COG0784	Response regulator, receiver
EXW45_RS08455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW45_RS08460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW45_RS08465	COG0741	lytic transglycosylase activity
EXW45_RS08475	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW45_RS08480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW45_RS08480	COG1776	CheC inhibitor of MCP methylation
EXW45_RS08490	COG1338	Plays a role in the flagellum-specific transport system
EXW45_RS08495	COG1987	bacterial-type flagellum assembly
EXW45_RS08505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW45_RS08510	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW45_RS08515	COG1419	protein localization to endoplasmic reticulum
EXW45_RS08520	COG4786	Flagellar basal body rod
EXW45_RS08525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW45_RS08565	COG0412	Dienelactone hydrolase
EXW45_RS08585	COG3764	Sortase (surface protein transpeptidase)
EXW45_RS08590	COG3764	Sortase (surface protein transpeptidase)
EXW45_RS08615	COG0583	DNA-binding transcription factor activity
EXW45_RS08620	COG3842	ATPase activity
EXW45_RS08635	COG1234	tRNA 3'-trailer cleavage
EXW45_RS08665	COG1686	Belongs to the peptidase S11 family
EXW45_RS08675	COG0406	alpha-ribazole phosphatase activity
EXW45_RS08690	COG1846	Transcriptional regulator
EXW45_RS08700	COG0367	asparagine synthase
EXW45_RS08730	COG1802	Transcriptional regulator
EXW45_RS08735	COG0697	spore germination
EXW45_RS08740	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS08740	COG1216	Glycosyl transferase, family 2
EXW45_RS08745	COG1757	Na H antiporter
EXW45_RS08750	COG0114	fumarate hydratase activity
EXW45_RS08760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS08770	COG0534	Mate efflux family protein
EXW45_RS08775	COG3340	Belongs to the peptidase S51 family
EXW45_RS08795	COG0785	Cytochrome C biogenesis protein
EXW45_RS08820	COG2733	membrane
EXW45_RS08855	COG1131	(ABC) transporter
EXW45_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS08905	COG0528	UMP kinase activity
EXW45_RS08915	COG1027	Aspartate ammonia-lyase
EXW45_RS08920	COG0281	malic enzyme
EXW45_RS08925	COG4191	Histidine kinase
EXW45_RS08930	COG0784	Response regulator, receiver
EXW45_RS08935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW45_RS08990	COG1051	belongs to the nudix hydrolase family
EXW45_RS09020	COG1695	Transcriptional regulator
EXW45_RS09030	COG0477	Major facilitator Superfamily
EXW45_RS09035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW45_RS09045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW45_RS09050	COG4166	transmembrane transport
EXW45_RS09055	COG2223	nitrite transmembrane transporter activity
EXW45_RS09060	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW45_RS09075	COG2244	polysaccharide biosynthetic process
EXW45_RS09080	COG0733	neurotransmitter:sodium symporter activity
EXW45_RS09090	COG5566	PFAM Mor transcription activator
EXW45_RS09095	COG2323	membrane
EXW45_RS09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW45_RS09120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW45_RS09125	COG0028	Belongs to the TPP enzyme family
EXW45_RS09145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW45_RS09170	COG2814	Major facilitator Superfamily
EXW45_RS09175	COG3384	dioxygenase
EXW45_RS09190	COG3279	Response regulator of the LytR AlgR family
EXW45_RS09195	COG0427	acetyl-CoA hydrolase
EXW45_RS09210	COG1073	alpha beta
EXW45_RS09215	COG4166	transmembrane transport
EXW45_RS09220	COG4977	sequence-specific DNA binding
EXW45_RS09245	COG4974	Belongs to the 'phage' integrase family
EXW45_RS09275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS09280	COG0745	RESPONSE REGULATOR receiver
EXW45_RS09295	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW45_RS09300	COG1054	Belongs to the UPF0176 family
EXW45_RS09310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW45_RS09315	COG0531	amino acid
EXW45_RS09350	COG0714	Associated with various cellular activities
EXW45_RS09360	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EXW45_RS09400	COG2390	Transcriptional regulator
EXW45_RS09410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS09415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW45_RS09430	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW45_RS09455	COG0006	proline dipeptidase activity
EXW45_RS09465	COG2132	Multicopper oxidase
EXW45_RS09475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW45_RS09500	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS09510	COG1276	copper resistance
EXW45_RS09510	COG2372	response to copper ion
EXW45_RS09515	COG4549	nuclear export factor GLE1
EXW45_RS09520	COG0697	spore germination
EXW45_RS09525	COG0583	DNA-binding transcription factor activity
EXW45_RS09530	COG1959	2 iron, 2 sulfur cluster binding
EXW45_RS09535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW45_RS09540	COG0778	Nitroreductase
EXW45_RS09555	COG0628	permease
EXW45_RS09565	COG1231	oxidoreductase activity
EXW45_RS09570	COG0523	cobalamin synthesis protein
EXW45_RS09580	COG0411	ABC transporter
EXW45_RS09600	COG0583	DNA-binding transcription factor activity
EXW45_RS09610	COG1942	4-Oxalocrotonate Tautomerase
EXW45_RS09630	COG1271	oxidase subunit
EXW45_RS09635	COG1294	oxidase, subunit
EXW45_RS09640	COG4988	ABC transporter
EXW45_RS09645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW45_RS09655	COG1216	Glycosyl transferase, family 2
EXW45_RS09685	COG1686	Belongs to the peptidase S11 family
EXW45_RS09700	COG0791	NLP P60 protein
EXW45_RS09700	COG1388	LysM domain
EXW45_RS09710	COG1132	(ABC) transporter
EXW45_RS09715	COG0745	RESPONSE REGULATOR receiver
EXW45_RS09720	COG5002	protein histidine kinase activity
EXW45_RS09730	COG0300	oxidoreductase activity
EXW45_RS09735	COG4122	O-methyltransferase activity
EXW45_RS09760	COG0460	homoserine dehydrogenase
EXW45_RS09785	COG1316	TRANSCRIPTIONal
EXW45_RS09795	COG0745	RESPONSE REGULATOR receiver
EXW45_RS09800	COG5002	protein histidine kinase activity
EXW45_RS09815	COG1285	pathogenesis
EXW45_RS09820	COG1247	-acetyltransferase
EXW45_RS09840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW45_RS09850	COG1082	Xylose isomerase domain protein TIM barrel
EXW45_RS09860	COG2814	Major facilitator Superfamily
EXW45_RS09865	COG1279	arginine transmembrane transporter activity
EXW45_RS09870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS09880	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW45_RS09975	COG4695	Portal protein
EXW45_RS10005	COG0577	efflux transmembrane transporter activity
EXW45_RS10010	COG2002	toxin-antitoxin pair type II binding
EXW45_RS10015	COG1404	Belongs to the peptidase S8 family
EXW45_RS10020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW45_RS10025	COG0640	Transcriptional regulator
EXW45_RS10030	COG0667	Aldo Keto reductase
EXW45_RS10035	COG2814	Major facilitator Superfamily
EXW45_RS10040	COG3152	Membrane
EXW45_RS10065	COG0840	transmembrane signaling receptor activity
EXW45_RS10080	COG3949	Membrane
EXW45_RS10085	COG0783	Belongs to the Dps family
EXW45_RS10100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW45_RS10110	COG1231	oxidoreductase activity
EXW45_RS10115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS10120	COG4989	oxidoreductase activity
EXW45_RS10125	COG0523	cobalamin synthesis protein
EXW45_RS10130	COG0456	acetyltransferase
EXW45_RS10135	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW45_RS10135	COG3443	Belongs to the bacterial solute-binding protein 9 family
EXW45_RS10160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW45_RS10170	COG4166	transmembrane transport
EXW45_RS10185	COG0406	alpha-ribazole phosphatase activity
EXW45_RS10195	COG5337	Spore coat protein CotH
EXW45_RS10200	COG1051	belongs to the nudix hydrolase family
EXW45_RS10205	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS10210	COG2244	polysaccharide biosynthetic process
EXW45_RS10220	COG0701	Predicted permease
EXW45_RS10225	COG3689	TIGRFAM TIGR03943 family protein
EXW45_RS10230	COG1607	acyl-coa hydrolase
EXW45_RS10240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS10255	COG0702	epimerase
EXW45_RS10260	COG2839	Protein conserved in bacteria
EXW45_RS10265	COG1253	flavin adenine dinucleotide binding
EXW45_RS10280	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS10285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW45_RS10305	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW45_RS10315	COG1876	peptidase activity
EXW45_RS10325	COG0154	amidase activity
EXW45_RS10330	COG2211	Major facilitator Superfamily
EXW45_RS10350	COG0561	phosphatase activity
EXW45_RS10360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW45_RS10380	COG1819	glycosyl
EXW45_RS10385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS10390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS10405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS10415	COG0456	acetyltransferase
EXW45_RS10450	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW45_RS10565	COG3874	Sporulation protein YtfJ
EXW45_RS10590	COG2226	methyltransferase
EXW45_RS10610	COG1082	Xylose isomerase domain protein TIM barrel
EXW45_RS10615	COG0346	lactoylglutathione lyase activity
EXW45_RS10625	COG0604	alcohol dehydrogenase
EXW45_RS10630	COG1595	DNA-templated transcription, initiation
EXW45_RS10655	COG0426	domain, Protein
EXW45_RS10655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW45_RS10665	COG0386	Belongs to the glutathione peroxidase family
EXW45_RS10670	COG1305	Transglutaminase-like
EXW45_RS10675	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW45_RS10680	COG0714	Associated with various cellular activities
EXW45_RS10690	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW45_RS10695	COG1140	nitrate reductase beta subunit
EXW45_RS10700	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW45_RS10705	COG2181	nitrate reductase activity
EXW45_RS10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW45_RS10715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW45_RS10720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW45_RS10725	COG0303	'Molybdopterin
EXW45_RS10730	COG0314	molybdopterin synthase activity
EXW45_RS10740	COG2223	nitrite transmembrane transporter activity
EXW45_RS10755	COG1648	precorrin-2 dehydrogenase activity
EXW45_RS10765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW45_RS10765	COG1587	Uroporphyrinogen-III synthase
EXW45_RS10770	COG2146	nitrite reductase [NAD(P)H] activity
EXW45_RS10775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW45_RS10780	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW45_RS10810	COG2359	stage V sporulation protein S
EXW45_RS10820	COG1418	mRNA catabolic process
EXW45_RS10825	COG0488	(ABC) transporter
EXW45_RS10845	COG1413	lyase activity
EXW45_RS10860	COG2136	Putative SAM-dependent methyltransferase
EXW45_RS10860	COG2521	methyltransferase
EXW45_RS10865	COG0018	arginyl-trna synthetase
EXW45_RS10905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW45_RS10910	COG0017	Asparaginyl-tRNA synthetase
EXW45_RS10915	COG0733	neurotransmitter:sodium symporter activity
EXW45_RS10940	COG2610	gluconate transmembrane transporter activity
EXW45_RS10945	COG1454	alcohol dehydrogenase
EXW45_RS10950	COG1794	racemase activity, acting on amino acids and derivatives
EXW45_RS10960	COG0456	acetyltransferase
EXW45_RS10965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW45_RS10975	COG1131	(ABC) transporter
EXW45_RS10980	COG4473	ABC transporter
EXW45_RS10990	COG0546	phosphoglycolate phosphatase activity
EXW45_RS11015	COG3250	beta-galactosidase activity
EXW45_RS11030	COG0768	penicillin binding
EXW45_RS11040	COG0204	Acyl-transferase
EXW45_RS11050	COG1272	protein, Hemolysin III
EXW45_RS11060	COG0805	protein transport
EXW45_RS11070	COG1307	EDD domain protein, DegV family
EXW45_RS11075	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW45_RS11080	COG1999	signal sequence binding
EXW45_RS11085	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW45_RS11090	COG0367	asparagine synthase
EXW45_RS11105	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW45_RS11110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS11115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW45_RS11135	COG1335	isochorismatase
EXW45_RS11140	COG0668	transmembrane transport
EXW45_RS11145	COG2203	Gaf domain
EXW45_RS11145	COG4585	Histidine kinase
EXW45_RS11150	COG2197	response regulator
EXW45_RS11155	COG1737	Transcriptional regulator
EXW45_RS11160	COG1064	alcohol dehydrogenase
EXW45_RS11175	COG1070	Carbohydrate kinase
EXW45_RS11185	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW45_RS11225	COG1174	glycine betaine transport
EXW45_RS11260	COG1253	flavin adenine dinucleotide binding
EXW45_RS11265	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS11270	COG5506	Protein of unknown function (DUF1694)
EXW45_RS11285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW45_RS11290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW45_RS11295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW45_RS11300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW45_RS11305	COG0456	acetyltransferase
EXW45_RS11310	COG3829	transcription factor binding
EXW45_RS11315	COG1509	lysine 2,3-aminomutase activity
EXW45_RS11350	COG4991	sh3 domain protein
EXW45_RS11350	COG0515	serine threonine protein kinase
EXW45_RS11350	COG3064	Membrane
EXW45_RS11355	COG4326	sporulation control protein
EXW45_RS11360	COG0671	phosphoesterase, PA-phosphatase related
EXW45_RS11365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW45_RS11375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW45_RS11495	COG1595	DNA-templated transcription, initiation
EXW45_RS11530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW45_RS11555	COG0300	oxidoreductase activity
EXW45_RS11575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW45_RS11575	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW45_RS11585	COG2814	Major facilitator Superfamily
EXW45_RS11595	COG0372	Belongs to the citrate synthase family
EXW45_RS11600	COG2079	MmgE PrpD family protein
EXW45_RS11605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW45_RS11610	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS11615	COG2084	Dehydrogenase
EXW45_RS11625	COG1280	lysine exporter protein (LysE YggA)
EXW45_RS11630	COG1024	Enoyl-CoA hydratase
EXW45_RS11645	COG0420	3'-5' exonuclease activity
EXW45_RS11670	COG2223	nitrite transmembrane transporter activity
EXW45_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS11680	COG1169	isochorismate synthase
EXW45_RS11685	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW45_RS11690	COG3433	isochorismatase activity
EXW45_RS11690	COG1535	isochorismatase
EXW45_RS11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW45_RS11700	COG3251	PFAM MbtH domain protein
EXW45_RS11705	COG2814	Major facilitator Superfamily
EXW45_RS11720	COG0776	regulation of translation
EXW45_RS11730	COG2318	DinB family
EXW45_RS11735	COG1115	amino acid carrier protein
EXW45_RS11750	COG2329	Antibiotic biosynthesis monooxygenase
EXW45_RS11755	COG1187	pseudouridine synthase activity
EXW45_RS11760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW45_RS11770	COG1136	(ABC) transporter
EXW45_RS11780	COG2814	Major facilitator Superfamily
EXW45_RS11795	COG0028	Belongs to the TPP enzyme family
EXW45_RS11805	COG2226	methyltransferase
EXW45_RS11840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW45_RS11850	COG2207	Transcriptional regulator
EXW45_RS11875	COG2755	lipolytic protein G-D-S-L family
EXW45_RS11875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW45_RS11885	COG5002	protein histidine kinase activity
EXW45_RS11895	COG0745	RESPONSE REGULATOR receiver
EXW45_RS11900	COG5002	protein histidine kinase activity
EXW45_RS11915	COG1846	Transcriptional regulator
EXW45_RS11955	COG1247	-acetyltransferase
EXW45_RS11980	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW45_RS11985	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW45_RS11995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS12040	COG0583	DNA-binding transcription factor activity
EXW45_RS12045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW45_RS12060	COG0583	DNA-binding transcription factor activity
EXW45_RS12065	COG2258	MOSC domain
EXW45_RS12075	COG1132	(ABC) transporter
EXW45_RS12080	COG1132	(ABC) transporter
EXW45_RS12120	COG1396	sequence-specific DNA binding
EXW45_RS12170	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW45_RS12175	COG1595	DNA-templated transcription, initiation
EXW45_RS12185	COG4122	O-methyltransferase activity
EXW45_RS12205	COG1649	PFAM Uncharacterised BCR, COG1649
EXW45_RS12225	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW45_RS12230	COG2971	BadF BadG BcrA BcrD
EXW45_RS12250	COG1846	Transcriptional regulator
EXW45_RS12265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS12315	COG1309	transcriptional regulator
EXW45_RS12330	COG0577	efflux transmembrane transporter activity
EXW45_RS12330	COG1136	(ABC) transporter
EXW45_RS12335	COG0500	methyltransferase
EXW45_RS12335	COG3615	Tellurite resistance protein tehB
EXW45_RS12345	COG3961	Belongs to the TPP enzyme family
EXW45_RS12375	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW45_RS12385	COG0110	maltose O-acetyltransferase activity
EXW45_RS12390	COG1136	(ABC) transporter
EXW45_RS12415	COG1686	Belongs to the peptidase S11 family
EXW45_RS12440	COG1760	l-serine dehydratase
EXW45_RS12445	COG1760	l-serine dehydratase
EXW45_RS12450	COG0814	amino acid
EXW45_RS12470	COG1533	DNA photolyase activity
EXW45_RS12475	COG0076	glutamate decarboxylase activity
EXW45_RS12485	COG0745	RESPONSE REGULATOR receiver
EXW45_RS12490	COG2205	protein histidine kinase activity
EXW45_RS12495	COG1136	(ABC) transporter
EXW45_RS12500	COG0577	efflux transmembrane transporter activity
EXW45_RS12510	COG0768	penicillin binding
EXW45_RS12515	COG1595	DNA-templated transcription, initiation
EXW45_RS12525	COG0768	penicillin binding
EXW45_RS12530	COG0768	penicillin binding
EXW45_RS12580	COG0697	spore germination
EXW45_RS12590	COG3397	chitin binding
EXW45_RS12595	COG0823	Involved in the tonB-independent uptake of proteins
EXW45_RS12605	COG1609	Transcriptional regulator
EXW45_RS12610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW45_RS12615	COG0561	phosphatase activity
EXW45_RS12620	COG0673	inositol 2-dehydrogenase activity
EXW45_RS12625	COG0738	Major facilitator superfamily
EXW45_RS12655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS12680	COG1309	transcriptional regulator
EXW45_RS12700	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS12705	COG0439	Biotin carboxylase
EXW45_RS12710	COG0511	ligase activity, forming carbon-carbon bonds
EXW45_RS12715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW45_RS12720	COG1024	Enoyl-CoA hydratase
EXW45_RS12725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW45_RS12730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW45_RS12770	COG0572	uridine kinase
EXW45_RS12780	COG2318	DinB family
EXW45_RS12785	COG1686	Belongs to the peptidase S11 family
EXW45_RS12810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW45_RS12835	COG2207	Transcriptional regulator
EXW45_RS12870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW45_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS12910	COG1733	regulation of RNA biosynthetic process
EXW45_RS12915	COG2226	methyltransferase
EXW45_RS12945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS12960	COG0693	protein deglycase activity
EXW45_RS12970	COG0577	efflux transmembrane transporter activity
EXW45_RS12970	COG1136	(ABC) transporter
EXW45_RS12985	COG0825	malonyl-CoA metabolic process
EXW45_RS13075	COG1063	alcohol dehydrogenase
EXW45_RS13085	COG2323	membrane
EXW45_RS13110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW45_RS13115	COG0693	protein deglycase activity
EXW45_RS13125	COG3386	PFAM SMP-30 Gluconolaconase
EXW45_RS13135	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW45_RS13140	COG3773	Cell wall hydrolase
EXW45_RS13150	COG0745	RESPONSE REGULATOR receiver
EXW45_RS13155	COG2205	protein histidine kinase activity
EXW45_RS13170	COG0488	(ABC) transporter
EXW45_RS13180	COG1136	(ABC) transporter
EXW45_RS13185	COG0577	efflux transmembrane transporter activity
EXW45_RS13205	COG0460	homoserine dehydrogenase
EXW45_RS13210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS13220	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW45_RS13265	COG0582	viral genome integration into host DNA
EXW45_RS13425	COG2124	cytochrome p450
EXW45_RS13470	COG0561	phosphatase activity
EXW45_RS13475	COG5002	protein histidine kinase activity
EXW45_RS13485	COG1819	glycosyl
EXW45_RS13490	COG1794	racemase activity, acting on amino acids and derivatives
EXW45_RS13515	COG2205	protein histidine kinase activity
EXW45_RS13530	COG0604	alcohol dehydrogenase
EXW45_RS13535	COG0671	phosphoesterase, PA-phosphatase related
EXW45_RS13540	COG0768	penicillin binding
EXW45_RS13585	COG2814	Major facilitator Superfamily
EXW45_RS13600	COG0584	glycerophosphoryl diester phosphodiesterase
EXW45_RS13615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS13620	COG0697	spore germination
EXW45_RS13655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW45_RS13665	COG2223	nitrite transmembrane transporter activity
EXW45_RS13690	COG0592	DNA-directed DNA polymerase activity
EXW45_RS13695	COG1051	belongs to the nudix hydrolase family
EXW45_RS13720	COG3878	Protein conserved in bacteria
EXW45_RS13745	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW45_RS13785	COG0322	excinuclease ABC activity
EXW45_RS13815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW45_RS13840	COG1011	Hydrolase
EXW45_RS13845	COG0745	RESPONSE REGULATOR receiver
EXW45_RS13850	COG5002	protein histidine kinase activity
EXW45_RS13865	COG1136	(ABC) transporter
EXW45_RS13870	COG0577	efflux transmembrane transporter activity
EXW45_RS13875	COG1523	belongs to the glycosyl hydrolase 13 family
EXW45_RS13880	COG3227	Zinc metalloprotease (Elastase)
EXW45_RS13885	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS13895	COG0201	protein transport
EXW45_RS13905	COG0697	spore germination
EXW45_RS13910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS13915	COG0604	alcohol dehydrogenase
EXW45_RS13960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS13975	COG2959	enzyme of heme biosynthesis
EXW45_RS14010	COG1309	transcriptional regulator
EXW45_RS14025	COG3284	Transcriptional regulator
EXW45_RS14040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS14045	COG1349	DNA-binding transcription factor activity
EXW45_RS14060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW45_RS14065	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW45_RS14070	COG0022	dehydrogenase e1 component
EXW45_RS14075	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW45_RS14085	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS14090	COG0456	acetyltransferase
EXW45_RS14090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW45_RS14095	COG0572	uridine kinase
EXW45_RS14135	COG4176	ABC-type proline glycine betaine transport system permease component
EXW45_RS14140	COG4175	Glycine betaine
EXW45_RS14140	COG0517	IMP dehydrogenase activity
EXW45_RS14170	COG2153	protein acetylation
EXW45_RS14180	COG3397	chitin binding
EXW45_RS14185	COG1819	glycosyl
EXW45_RS14200	COG2205	protein histidine kinase activity
EXW45_RS14205	COG2226	methyltransferase
EXW45_RS14210	COG2315	Protein conserved in bacteria
EXW45_RS14260	COG3973	AAA domain
EXW45_RS14270	COG2105	PFAM AIG2 family protein
EXW45_RS14275	COG0514	ATP-dependent DNA helicase (RecQ)
EXW45_RS14305	COG4824	toxin secretion phage lysis holin
EXW45_RS14325	COG4637	Psort location Cytoplasmic, score
EXW45_RS14350	COG3397	chitin binding
EXW45_RS14355	COG2318	DinB family
EXW45_RS14365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW45_RS14370	COG1115	amino acid carrier protein
EXW45_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS14380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW45_RS14390	COG3938	Belongs to the proline racemase family
EXW45_RS14395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW45_RS14435	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW45_RS14440	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS14450	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW45_RS14455	COG0519	Catalyzes the synthesis of GMP from XMP
EXW45_RS14460	COG4166	transmembrane transport
EXW45_RS14470	COG4948	Mandelate Racemase Muconate Lactonizing
EXW45_RS14485	COG0667	Aldo Keto reductase
EXW45_RS14515	COG2226	methyltransferase
EXW45_RS14525	COG2936	dipeptidyl-peptidase activity
EXW45_RS14530	COG5002	protein histidine kinase activity
EXW45_RS14535	COG0745	RESPONSE REGULATOR receiver
EXW45_RS14565	COG1164	Oligoendopeptidase f
EXW45_RS14570	COG0531	amino acid
EXW45_RS14575	COG1522	sequence-specific DNA binding
EXW45_RS14595	COG1307	EDD domain protein, DegV family
EXW45_RS14640	COG2814	Major facilitator Superfamily
EXW45_RS14650	COG1664	Polymer-forming cytoskeletal
EXW45_RS14655	COG0789	Transcriptional regulator
EXW45_RS14660	COG4533	DNA binding
EXW45_RS14665	COG0477	Major facilitator Superfamily
EXW45_RS14665	COG2814	Major facilitator Superfamily
EXW45_RS14685	COG2261	transglycosylase associated protein
EXW45_RS14700	COG2226	methyltransferase
EXW45_RS14740	COG0436	Aminotransferase
EXW45_RS14745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW45_RS14805	COG0628	permease
EXW45_RS14815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW45_RS14820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW45_RS14825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW45_RS14855	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW45_RS14885	COG0697	spore germination
EXW45_RS14890	COG2318	DinB family
EXW45_RS14920	COG0346	lactoylglutathione lyase activity
EXW45_RS14935	COG0861	Integral membrane protein TerC family
EXW45_RS14940	COG1368	sulfuric ester hydrolase activity
EXW45_RS14945	COG0488	(ABC) transporter
EXW45_RS14955	COG2409	Drug exporters of the RND superfamily
EXW45_RS14955	COG1033	growth of symbiont in host cell
EXW45_RS14960	COG1309	transcriptional regulator
EXW45_RS14975	COG0287	Prephenate dehydrogenase
EXW45_RS14990	COG1605	Chorismate mutase
EXW45_RS14990	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW45_RS15020	COG1388	LysM domain
EXW45_RS15020	COG3584	3D domain protein
EXW45_RS15045	COG1879	ABC-type sugar transport system periplasmic component
EXW45_RS15050	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW45_RS15055	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW45_RS15065	COG2390	Transcriptional regulator
EXW45_RS15100	COG2329	Antibiotic biosynthesis monooxygenase
EXW45_RS15115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS15120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW45_RS15130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW45_RS15135	COG4187	Peptidase family M20/M25/M40
EXW45_RS15140	COG1414	Transcriptional regulator
EXW45_RS15145	COG0833	amino acid
EXW45_RS15160	COG3239	Fatty acid desaturase
EXW45_RS15170	COG1785	Belongs to the alkaline phosphatase family
EXW45_RS15180	COG3655	Transcriptional regulator
EXW45_RS15195	COG4377	Putative membrane peptidase family (DUF2324)
EXW45_RS15205	COG3279	Response regulator of the LytR AlgR family
EXW45_RS15220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS15225	COG0346	lactoylglutathione lyase activity
EXW45_RS15245	COG0714	Associated with various cellular activities
EXW45_RS15295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW45_RS15300	COG0753	catalase activity
EXW45_RS15335	COG0714	Associated with various cellular activities
EXW45_RS15430	COG0778	Nitroreductase
EXW45_RS15435	COG1846	Transcriptional regulator
EXW45_RS15470	COG1725	Transcriptional regulator
EXW45_RS15505	COG0590	tRNA wobble adenosine to inosine editing
EXW45_RS15505	COG0037	tRNA processing
EXW45_RS15510	COG0456	acetyltransferase
EXW45_RS15530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS15545	COG0642	Histidine kinase
EXW45_RS15550	COG0745	RESPONSE REGULATOR receiver
EXW45_RS15555	COG0596	Alpha beta hydrolase
EXW45_RS15565	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW45_RS15565	COG0456	acetyltransferase
EXW45_RS15590	COG0730	response to heat
EXW45_RS15600	COG0833	amino acid
EXW45_RS15610	COG4335	DNA alkylation repair
EXW45_RS15630	COG0384	phenazine biosynthesis protein PhzF
EXW45_RS15650	COG0768	penicillin binding
EXW45_RS15690	COG1984	allophanate hydrolase subunit 2
EXW45_RS15695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW45_RS15700	COG1414	Transcriptional regulator
EXW45_RS15720	COG3142	Participates in the control of copper homeostasis
EXW45_RS15725	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW45_RS15730	COG0640	Transcriptional regulator
EXW45_RS15745	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS15760	COG3314	Sporulation integral membrane protein YlbJ
EXW45_RS15775	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW45_RS15790	COG3848	Pyruvate phosphate dikinase
EXW45_RS15790	COG0574	Belongs to the PEP-utilizing enzyme family
EXW45_RS15795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS15815	COG1063	alcohol dehydrogenase
EXW45_RS15835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW45_RS15850	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS15855	COG2267	carboxylic ester hydrolase activity
EXW45_RS15860	COG1335	isochorismatase
EXW45_RS15885	COG0583	DNA-binding transcription factor activity
EXW45_RS15935	COG0598	Magnesium transport protein CorA
EXW45_RS15980	COG0415	Belongs to the DNA photolyase family
EXW45_RS15985	COG0288	reversible hydration of carbon dioxide
EXW45_RS15995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW45_RS16000	COG5609	conserved protein (DUF2294)
EXW45_RS16015	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW45_RS16050	COG0456	acetyltransferase
EXW45_RS16090	COG1329	Transcriptional regulator
EXW45_RS16105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS16115	COG2267	carboxylic ester hydrolase activity
EXW45_RS16120	COG4641	Protein conserved in bacteria
EXW45_RS16135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS16145	COG0798	PFAM Bile acid sodium symporter
EXW45_RS16150	COG0346	lactoylglutathione lyase activity
EXW45_RS16155	COG0640	Transcriptional regulator
EXW45_RS16170	COG3320	Male sterility
EXW45_RS16170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW45_RS16175	COG1309	transcriptional regulator
EXW45_RS16185	COG2186	Transcriptional regulator
EXW45_RS16200	COG0814	amino acid
EXW45_RS16205	COG0697	spore germination
EXW45_RS16210	COG2814	Major facilitator Superfamily
EXW45_RS16215	COG1309	transcriptional regulator
EXW45_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS16225	COG1522	sequence-specific DNA binding
EXW45_RS16240	COG0346	lactoylglutathione lyase activity
EXW45_RS16290	COG2814	Major facilitator Superfamily
EXW45_RS16300	COG4895	conserved protein (DUF2196)
EXW45_RS16335	COG0675	Transposase, IS605 OrfB family
EXW45_RS16350	COG0745	RESPONSE REGULATOR receiver
EXW45_RS16355	COG5002	protein histidine kinase activity
EXW45_RS16355	COG3850	Histidine kinase
EXW45_RS16380	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW45_RS16410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW45_RS16420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW45_RS16435	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW45_RS16455	COG0577	efflux transmembrane transporter activity
EXW45_RS16475	COG3850	Histidine kinase
EXW45_RS16475	COG5002	protein histidine kinase activity
EXW45_RS16485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS16515	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW45_RS16535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW45_RS16570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW45_RS16610	COG2814	Major facilitator Superfamily
EXW45_RS16690	COG2849	repeat protein
EXW45_RS16940	COG0477	Major facilitator Superfamily
EXW45_RS16960	COG1846	Transcriptional regulator
EXW45_RS16965	COG2814	Major facilitator Superfamily
EXW45_RS16975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW45_RS16980	COG1131	(ABC) transporter
EXW45_RS17000	COG2031	fatty acid transporter
EXW45_RS17010	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW45_RS17045	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW45_RS17065	COG1288	antiporter activity
EXW45_RS17070	COG2356	endonuclease I
EXW45_RS17080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW45_RS17095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS17115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW45_RS17125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW45_RS17140	COG1733	regulation of RNA biosynthetic process
EXW45_RS17145	COG0778	Nitroreductase
EXW45_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS17175	COG1131	(ABC) transporter
EXW45_RS17200	COG1011	Hydrolase
EXW45_RS17210	COG2365	Tyrosine phosphatase family
EXW45_RS17235	COG0577	efflux transmembrane transporter activity
EXW45_RS17240	COG1136	(ABC) transporter
EXW45_RS17245	COG2205	protein histidine kinase activity
EXW45_RS17250	COG0745	RESPONSE REGULATOR receiver
EXW45_RS17265	COG0346	lactoylglutathione lyase activity
EXW45_RS17270	COG1940	carbohydrate kinase activity
EXW45_RS17275	COG0110	maltose O-acetyltransferase activity
EXW45_RS17305	COG0628	permease
EXW45_RS17335	COG0500	methyltransferase
EXW45_RS17345	COG0477	Major facilitator Superfamily
EXW45_RS17375	COG1253	flavin adenine dinucleotide binding
EXW45_RS17380	COG0789	Transcriptional regulator
EXW45_RS17390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW45_RS17415	COG0697	spore germination
EXW45_RS17420	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW45_RS17425	COG3813	Protein conserved in bacteria
EXW45_RS17430	COG2706	6-phosphogluconolactonase activity
EXW45_RS17435	COG1070	Carbohydrate kinase
EXW45_RS17445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EXW45_RS17450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW45_RS17460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW45_RS17465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW45_RS17470	COG0604	alcohol dehydrogenase
EXW45_RS17475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW45_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS17510	COG0456	acetyltransferase
EXW45_RS17525	COG2309	aminopeptidase activity
EXW45_RS17535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW45_RS17535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW45_RS17540	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW45_RS17540	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW45_RS17545	COG1733	regulation of RNA biosynthetic process
EXW45_RS17560	COG0656	L-ascorbic acid biosynthetic process
EXW45_RS17565	COG2814	Major facilitator Superfamily
EXW45_RS17580	COG0346	lactoylglutathione lyase activity
EXW45_RS17585	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW45_RS17590	COG0659	secondary active sulfate transmembrane transporter activity
EXW45_RS17605	COG0814	amino acid
EXW45_RS17630	COG1393	Belongs to the ArsC family
EXW45_RS17635	COG1733	regulation of RNA biosynthetic process
EXW45_RS17640	COG2188	Transcriptional regulator
EXW45_RS17645	COG0673	inositol 2-dehydrogenase activity
EXW45_RS17650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EXW45_RS17660	COG1733	regulation of RNA biosynthetic process
EXW45_RS17665	COG1733	regulation of RNA biosynthetic process
EXW45_RS17680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS17700	COG0384	phenazine biosynthesis protein PhzF
EXW45_RS17725	COG0318	PFAM AMP-dependent synthetase and ligase
EXW45_RS17730	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW45_RS17735	COG1733	regulation of RNA biosynthetic process
EXW45_RS17740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW45_RS17760	COG1191	sigma factor activity
EXW45_RS17775	COG1876	peptidase activity
EXW45_RS17810	COG5002	protein histidine kinase activity
EXW45_RS17820	COG0657	acetylesterase activity
EXW45_RS17830	COG2814	Major facilitator Superfamily
EXW45_RS17835	COG1309	transcriptional regulator
EXW45_RS17840	COG1280	lysine exporter protein (LysE YggA)
EXW45_RS17885	COG1151	hydroxylamine reductase activity
EXW45_RS17895	COG3757	hydrolase, family 25
EXW45_RS17895	COG3409	Peptidoglycan-binding domain 1 protein
EXW45_RS17975	COG1695	Transcriptional regulator
EXW45_RS17980	COG0604	alcohol dehydrogenase
EXW45_RS17985	COG1113	amino acid transport
EXW45_RS17990	COG2814	Major facilitator Superfamily
EXW45_RS18020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW45_RS18025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW45_RS18035	COG1131	(ABC) transporter
EXW45_RS18055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS18060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS18065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS18090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS18105	COG0583	DNA-binding transcription factor activity
EXW45_RS18125	COG1193	negative regulation of DNA recombination
EXW45_RS18145	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW45_RS18150	COG1164	Oligoendopeptidase f
EXW45_RS18160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW45_RS18165	COG0789	Transcriptional regulator
EXW45_RS18165	COG4978	Transcriptional regulator
EXW45_RS18180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW45_RS18205	COG0584	glycerophosphoryl diester phosphodiesterase
EXW45_RS18215	COG0640	Transcriptional regulator
EXW45_RS18220	COG0604	alcohol dehydrogenase
EXW45_RS18230	COG0457	Tetratricopeptide repeat
EXW45_RS18240	COG2808	Putative FMN-binding domain
EXW45_RS18245	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW45_RS18255	COG0385	Bile acid
EXW45_RS18260	COG0277	FAD linked oxidase domain protein
EXW45_RS18300	COG1285	pathogenesis
EXW45_RS18315	COG2514	catechol 2,3-dioxygenase activity
EXW45_RS18320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS18325	COG1126	abc transporter atp-binding protein
EXW45_RS18330	COG0765	amino acid transport
EXW45_RS18335	COG2720	vancomycin resistance protein
EXW45_RS18355	COG2176	DNA-directed DNA polymerase activity
EXW45_RS18360	COG1278	Cold shock
EXW45_RS18370	COG0716	FMN binding
EXW45_RS18420	COG0739	heme binding
EXW45_RS18425	COG0741	lytic transglycosylase activity
EXW45_RS18430	COG3757	hydrolase, family 25
EXW45_RS18430	COG3409	Peptidoglycan-binding domain 1 protein
EXW45_RS18435	COG0739	heme binding
EXW45_RS18480	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS18490	COG0165	Argininosuccinate lyase
EXW45_RS18505	COG4145	pantothenate transmembrane transporter activity
EXW45_RS18515	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS18530	COG1657	PFAM Prenyltransferase squalene oxidase
EXW45_RS18535	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW45_RS18540	COG2962	Rard protein
EXW45_RS18560	COG0489	protein tyrosine kinase activity
EXW45_RS18570	COG0314	molybdopterin synthase activity
EXW45_RS18575	COG0303	'Molybdopterin
EXW45_RS18580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW45_RS18585	COG2116	formate transmembrane transporter activity
EXW45_RS18595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW45_RS18600	COG5609	conserved protein (DUF2294)
EXW45_RS18605	COG2427	Protein of unknown function (DUF1641)
EXW45_RS18610	COG3383	formate dehydrogenase (NAD+) activity
EXW45_RS18615	COG0697	spore germination
EXW45_RS18670	COG2226	methyltransferase
EXW45_RS18675	COG4166	transmembrane transport
EXW45_RS18680	COG4166	transmembrane transport
EXW45_RS18685	COG4166	transmembrane transport
EXW45_RS18690	COG1316	TRANSCRIPTIONal
EXW45_RS18700	COG1595	DNA-templated transcription, initiation
EXW45_RS18715	COG1131	(ABC) transporter
EXW45_RS18735	COG0673	inositol 2-dehydrogenase activity
EXW45_RS18740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW45_RS18745	COG0187	DNA topoisomerase II activity
EXW45_RS18750	COG1832	CoA-binding protein
EXW45_RS18755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW45_RS18760	COG0745	RESPONSE REGULATOR receiver
EXW45_RS18780	COG4841	protein insertion into membrane
EXW45_RS18785	COG0824	Thioesterase
EXW45_RS18810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW45_RS18820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW45_RS18825	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW45_RS18855	COG2211	Major facilitator Superfamily
EXW45_RS18865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW45_RS18890	COG0183	Belongs to the thiolase family
EXW45_RS18895	COG0318	PFAM AMP-dependent synthetase and ligase
EXW45_RS18900	COG1268	BioY protein
EXW45_RS18905	COG0318	PFAM AMP-dependent synthetase and ligase
EXW45_RS18920	COG1396	sequence-specific DNA binding
EXW45_RS18965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS18975	COG5002	protein histidine kinase activity
EXW45_RS18980	COG0400	carboxylic ester hydrolase activity
EXW45_RS18985	COG0346	lactoylglutathione lyase activity
EXW45_RS18990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW45_RS19000	COG0069	glutamate synthase activity
EXW45_RS19005	COG1902	pentaerythritol trinitrate reductase activity
EXW45_RS19010	COG1329	Transcriptional regulator
EXW45_RS19015	COG0010	Belongs to the arginase family
EXW45_RS19040	COG2226	methyltransferase
EXW45_RS19075	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW45_RS19080	COG0785	Cytochrome C biogenesis protein
EXW45_RS19090	COG1473	amidohydrolase
EXW45_RS19100	COG1131	(ABC) transporter
EXW45_RS19115	COG0583	DNA-binding transcription factor activity
EXW45_RS19125	COG1346	cytolysis
EXW45_RS19140	COG0730	response to heat
EXW45_RS19165	COG1132	(ABC) transporter
EXW45_RS19170	COG1132	(ABC) transporter
EXW45_RS19175	COG3763	UPF0154 protein
EXW45_RS19210	COG3639	organic phosphonate transmembrane transporter activity
EXW45_RS19220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS19225	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS19235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW45_RS19255	COG1695	Transcriptional regulator
EXW45_RS19260	COG1132	(ABC) transporter
EXW45_RS19290	COG0367	asparagine synthase
EXW45_RS19295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW45_RS19300	COG0110	maltose O-acetyltransferase activity
EXW45_RS19305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW45_RS19320	COG1442	glycosyl transferase family 8
EXW45_RS19320	COG1216	Glycosyl transferase, family 2
EXW45_RS19335	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS19345	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS19355	COG0463	Glycosyl transferase, family 2
EXW45_RS19355	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW45_RS19360	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS19365	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS19370	COG1086	Polysaccharide biosynthesis protein
EXW45_RS19375	COG0489	protein tyrosine kinase activity
EXW45_RS19385	COG0174	glutamine synthetase
EXW45_RS19390	COG0789	Transcriptional regulator
EXW45_RS19395	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW45_RS19400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW45_RS19405	COG2860	membrane
EXW45_RS19415	COG0464	growth
EXW45_RS19445	COG3584	3D domain protein
EXW45_RS19445	COG1388	LysM domain
EXW45_RS19450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW45_RS19450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW45_RS19450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW45_RS19455	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW45_RS19460	COG1349	DNA-binding transcription factor activity
EXW45_RS19465	COG1979	alcohol dehydrogenase
EXW45_RS19470	COG2322	membrane
EXW45_RS19480	COG1113	amino acid transport
EXW45_RS19490	COG1408	metallophosphoesterase
EXW45_RS19495	COG2116	formate transmembrane transporter activity
EXW45_RS19510	COG2217	Heavy metal translocating P-type atpase
EXW45_RS19515	COG2608	mercury ion transmembrane transporter activity
EXW45_RS19520	COG1937	Protein conserved in bacteria
EXW45_RS19535	COG2819	hydrolase of the alpha beta superfamily
EXW45_RS19540	COG1120	ATPase activity
EXW45_RS19545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS19550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS19555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS19560	COG0708	Exodeoxyribonuclease III
EXW45_RS19565	COG2169	Transcriptional regulator
EXW45_RS19570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW45_RS19575	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW45_RS19585	COG2364	Membrane
EXW45_RS19605	COG3300	MHYT domain
EXW45_RS19605	COG5001	Diguanylate cyclase
EXW45_RS19645	COG1346	cytolysis
EXW45_RS19650	COG1380	Effector of murein hydrolase LrgA
EXW45_RS19655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW45_RS19665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW45_RS19675	COG2188	Transcriptional regulator
EXW45_RS19680	COG2723	6-phospho-beta-galactosidase activity
EXW45_RS19685	COG0840	transmembrane signaling receptor activity
EXW45_RS19695	COG1404	Belongs to the peptidase S8 family
EXW45_RS19700	COG3773	Cell wall hydrolase
EXW45_RS19710	COG1368	sulfuric ester hydrolase activity
EXW45_RS19715	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW45_RS19725	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW45_RS19735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW45_RS19745	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW45_RS19755	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW45_RS19760	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW45_RS19760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW45_RS19770	COG2359	stage V sporulation protein S
EXW45_RS19775	COG1692	metallophosphoesterase
EXW45_RS19795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW45_RS19800	COG1426	Protein conserved in bacteria
EXW45_RS19815	COG0300	oxidoreductase activity
EXW45_RS19820	COG0612	Peptidase, M16
EXW45_RS19825	COG0612	Peptidase, M16
EXW45_RS19830	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW45_RS19835	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW45_RS19840	COG3845	ABC transporter
EXW45_RS19845	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW45_RS19850	COG2188	Transcriptional regulator
EXW45_RS19855	COG1674	ftsk spoiiie
EXW45_RS19865	COG0740	serine-type endopeptidase activity
EXW45_RS19870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW45_RS19880	COG0527	aspartate kinase activity
EXW45_RS19885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW45_RS19890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW45_RS19895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW45_RS19900	COG1873	PFAM PRC-barrel domain
EXW45_RS19905	COG0612	Peptidase, M16
EXW45_RS19910	COG0726	polysaccharide deacetylase
EXW45_RS19925	COG0196	riboflavin kinase activity
EXW45_RS19940	COG1550	Protein conserved in bacteria
EXW45_RS19950	COG1358	cellular component organization or biogenesis
EXW45_RS19955	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW45_RS19960	COG0195	Participates in both transcription termination and antitermination
EXW45_RS19980	COG0750	zinc metalloprotease
EXW45_RS19990	COG4589	Belongs to the CDS family
EXW45_RS20000	COG0233	cytoplasmic translational termination
EXW45_RS20010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW45_RS20035	COG4974	Belongs to the 'phage' integrase family
EXW45_RS20045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW45_RS20050	COG0758	DNA mediated transformation
EXW45_RS20055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW45_RS20095	COG1837	Belongs to the UPF0109 family
EXW45_RS20105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW45_RS20115	COG0552	protein localization to endoplasmic reticulum
EXW45_RS20120	COG1196	nuclear chromosome segregation
EXW45_RS20130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW45_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS20140	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW45_RS20150	COG1349	DNA-binding transcription factor activity
EXW45_RS20150	COG2050	protein possibly involved in aromatic compounds catabolism
EXW45_RS20155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW45_RS20160	COG1461	Dihydroxyacetone kinase
EXW45_RS20165	COG1302	Protein conserved in bacteria
EXW45_RS20180	COG1564	THIamine pyrophosphokinase
EXW45_RS20185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW45_RS20195	COG0515	serine threonine protein kinase
EXW45_RS20195	COG2815	serine threonine protein kinase
EXW45_RS20200	COG0631	protein serine/threonine phosphatase activity
EXW45_RS20205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW45_RS20210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW45_RS20210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW45_RS20220	COG0242	peptide deformylase activity
EXW45_RS20225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW45_RS20230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW45_RS20235	COG1758	RNA polymerase activity
EXW45_RS20250	COG1561	YicC-like family, N-terminal region
EXW45_RS20255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW45_RS20265	COG0006	proline dipeptidase activity
EXW45_RS20285	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW45_RS20310	COG0543	2 iron, 2 sulfur cluster binding
EXW45_RS20345	COG0564	pseudouridine synthase activity
EXW45_RS20365	COG3599	regulation of cell shape
EXW45_RS20370	COG2302	S4 RNA-binding domain
EXW45_RS20375	COG0762	integral membrane protein
EXW45_RS20385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW45_RS20395	COG1873	PFAM PRC-barrel domain
EXW45_RS20400	COG1191	sigma factor activity
EXW45_RS20405	COG1191	sigma factor activity
EXW45_RS20415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW45_RS20420	COG0849	cell division
EXW45_RS20425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW45_RS20440	COG0772	Belongs to the SEDS family
EXW45_RS20455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW45_RS20460	COG0768	penicillin binding
EXW45_RS20465	COG0768	penicillin binding
EXW45_RS20470	COG4839	cell division protein FtsL
EXW45_RS20485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW45_RS20500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW45_RS20505	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW45_RS20515	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW45_RS20520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW45_RS20525	COG3314	Sporulation integral membrane protein YlbJ
EXW45_RS20535	COG0742	ribosomal rna small subunit methyltransferase
EXW45_RS20550	COG3679	Belongs to the UPF0342 family
EXW45_RS20555	COG0406	alpha-ribazole phosphatase activity
EXW45_RS20570	COG2340	Cysteine-rich secretory protein family
EXW45_RS20585	COG3336	cytochrome c oxidase
EXW45_RS20600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW45_RS20620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW45_RS20625	COG0772	Belongs to the SEDS family
EXW45_RS20630	COG4838	Belongs to the UPF0358 family
EXW45_RS20635	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW45_RS20640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW45_RS20650	COG4896	Protein conserved in bacteria
EXW45_RS20665	COG1217	gtp-binding protein TYPA
EXW45_RS20675	COG0483	inositol monophosphate 1-phosphatase activity
EXW45_RS20695	COG1982	Orn Lys Arg decarboxylase major
EXW45_RS20745	COG0022	dehydrogenase e1 component
EXW45_RS20750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW45_RS20765	COG0561	phosphatase activity
EXW45_RS20775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW45_RS20780	COG0569	domain protein
EXW45_RS20795	COG2171	N-acyltransferase activity
EXW45_RS20800	COG0583	DNA-binding transcription factor activity
EXW45_RS20805	COG0517	IMP dehydrogenase activity
EXW45_RS20815	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW45_RS20825	COG4703	Protein of unknown function (DUF1797)
EXW45_RS20840	COG2200	EAL domain
EXW45_RS20845	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS20850	COG1408	metallophosphoesterase
EXW45_RS20860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EXW45_RS20895	COG2814	Major facilitator Superfamily
EXW45_RS20920	COG3209	COG3209 Rhs family protein
EXW45_RS20930	COG2205	protein histidine kinase activity
EXW45_RS20940	COG0436	Aminotransferase
EXW45_RS20945	COG1609	Transcriptional regulator
EXW45_RS20950	COG3833	ABC-type maltose transport systems, permease component
EXW45_RS20955	COG1175	transmembrane transport
EXW45_RS20960	COG2182	Extracellular solute-binding protein
EXW45_RS20970	COG0366	Alpha amylase catalytic
EXW45_RS20975	COG3842	ATPase activity
EXW45_RS21015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW45_RS21020	COG0183	Belongs to the thiolase family
EXW45_RS21050	COG1695	Transcriptional regulator
EXW45_RS21055	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS21075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW45_RS21080	COG0436	Aminotransferase
EXW45_RS21115	COG2084	Dehydrogenase
EXW45_RS21125	COG2199	diguanylate cyclase activity
EXW45_RS21130	COG0778	Nitroreductase
EXW45_RS21155	COG2190	(PTS) system
EXW45_RS21155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW45_RS21155	COG1263	PTS System
EXW45_RS21160	COG3711	transcriptional antiterminator
EXW45_RS21170	COG2188	Transcriptional regulator
EXW45_RS21180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW45_RS21205	COG1547	Domain of unknown function (DUF309)
EXW45_RS21210	COG0456	acetyltransferase
EXW45_RS21215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW45_RS21220	COG4086	secreted protein
EXW45_RS21225	COG0561	phosphatase activity
EXW45_RS21230	COG0697	spore germination
EXW45_RS21245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW45_RS21270	COG0733	neurotransmitter:sodium symporter activity
EXW45_RS21290	COG1686	Belongs to the peptidase S11 family
EXW45_RS21295	COG1725	Transcriptional regulator
EXW45_RS21300	COG1131	(ABC) transporter
EXW45_RS21320	COG1846	Transcriptional regulator
EXW45_RS21335	COG0598	Magnesium transport protein CorA
EXW45_RS21360	COG4974	Belongs to the 'phage' integrase family
EXW45_RS21370	COG0735	belongs to the Fur family
EXW45_RS21375	COG1300	Membrane
EXW45_RS21395	COG0667	Aldo Keto reductase
EXW45_RS21400	COG0656	L-ascorbic acid biosynthetic process
EXW45_RS21405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW45_RS21405	COG0456	acetyltransferase
EXW45_RS21415	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS21415	COG1525	nuclease
EXW45_RS21415	COG4085	toxin activity
EXW45_RS21425	COG0596	Alpha beta hydrolase
EXW45_RS21430	COG2056	Na+-H+ antiporter family
EXW45_RS21435	COG1609	Transcriptional regulator
EXW45_RS21440	COG0456	acetyltransferase
EXW45_RS21445	COG1073	alpha beta
EXW45_RS21460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW45_RS21460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW45_RS21465	COG0307	riboflavin synthase, alpha
EXW45_RS21490	COG4106	trans-aconitate 2-methyltransferase activity
EXW45_RS21495	COG1073	alpha beta
EXW45_RS21495	COG2226	methyltransferase
EXW45_RS21510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW45_RS21520	COG1757	Na H antiporter
EXW45_RS21525	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS21535	COG1522	sequence-specific DNA binding
EXW45_RS21555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW45_RS21560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW45_RS21580	COG0300	oxidoreductase activity
EXW45_RS21585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS21590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW45_RS21595	COG1760	l-serine dehydratase
EXW45_RS21600	COG1760	l-serine dehydratase
EXW45_RS21630	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW45_RS21635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS21650	COG1376	ErfK ybiS ycfS ynhG family protein
EXW45_RS21655	COG4129	membrane
EXW45_RS21660	COG1126	abc transporter atp-binding protein
EXW45_RS21665	COG0765	amino acid transport
EXW45_RS21670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW45_RS21690	COG2323	membrane
EXW45_RS21695	COG0772	Belongs to the SEDS family
EXW45_RS21700	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW45_RS21705	COG0022	dehydrogenase e1 component
EXW45_RS21710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW45_RS21715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW45_RS21730	COG0280	phosphate acetyltransferase
EXW45_RS21735	COG3290	protein histidine kinase activity
EXW45_RS21735	COG3829	transcription factor binding
EXW45_RS21745	COG0584	glycerophosphoryl diester phosphodiesterase
EXW45_RS21750	COG3093	addiction module antidote protein HigA
EXW45_RS21760	COG0745	RESPONSE REGULATOR receiver
EXW45_RS21765	COG0750	zinc metalloprotease
EXW45_RS21770	COG0497	DNA recombination
EXW45_RS21780	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW45_RS21790	COG0142	geranyltranstransferase activity
EXW45_RS21815	COG1302	Protein conserved in bacteria
EXW45_RS21820	COG0439	Biotin carboxylase
EXW45_RS21825	COG0511	ligase activity, forming carbon-carbon bonds
EXW45_RS21870	COG3854	ATPases associated with a variety of cellular activities
EXW45_RS21890	COG0006	proline dipeptidase activity
EXW45_RS21905	COG3872	metal-dependent enzyme
EXW45_RS21915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW45_RS21945	COG0095	Lipoate-protein ligase
EXW45_RS21950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS21960	COG1609	Transcriptional regulator
EXW45_RS21970	COG2076	Multidrug Resistance protein
EXW45_RS21975	COG2076	Multidrug Resistance protein
EXW45_RS22010	COG1131	(ABC) transporter
EXW45_RS22015	COG1725	Transcriptional regulator
EXW45_RS22030	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW45_RS22045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW45_RS22100	COG4970	Tfp pilus assembly protein FimT
EXW45_RS22110	COG1459	type II secretion system
EXW45_RS22115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW45_RS22170	COG1410	methionine synthase
EXW45_RS22170	COG0646	methionine synthase
EXW45_RS22175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW45_RS22175	COG0646	methionine synthase
EXW45_RS22180	COG0626	cystathionine gamma-synthase activity
EXW45_RS22185	COG0626	cystathionine gamma-synthase activity
EXW45_RS22205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS22215	COG1940	carbohydrate kinase activity
EXW45_RS22220	COG4483	Protein conserved in bacteria
EXW45_RS22225	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW45_RS22230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW45_RS22235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW45_RS22240	COG0704	Plays a role in the regulation of phosphate uptake
EXW45_RS22250	COG0573	inorganic phosphate transmembrane transporter activity
EXW45_RS22255	COG0573	inorganic phosphate transmembrane transporter activity
EXW45_RS22260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW45_RS22265	COG0768	penicillin binding
EXW45_RS22270	COG0477	Major facilitator Superfamily
EXW45_RS22275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW45_RS22300	COG0735	belongs to the Fur family
EXW45_RS22305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW45_RS22310	COG1121	(ABC) transporter
EXW45_RS22315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS22345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW45_RS22350	COG2384	SAM-dependent methyltransferase
EXW45_RS22355	COG2010	Cytochrome c
EXW45_RS22360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW45_RS22365	COG0358	DNA primase activity
EXW45_RS22375	COG0517	IMP dehydrogenase activity
EXW45_RS22390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW45_RS22395	COG0295	cytidine deaminase activity
EXW45_RS22400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW45_RS22410	COG1480	7TM receptor with intracellular HD hydrolase
EXW45_RS22415	COG1702	phosphate starvation-inducible protein PhoH
EXW45_RS22430	COG1610	YqeY-like protein
EXW45_RS22435	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW45_RS22440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW45_RS22445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW45_RS22475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW45_RS22480	COG1733	regulation of RNA biosynthetic process
EXW45_RS22505	COG1466	dna polymerase III delta subunit
EXW45_RS22515	COG0658	competence protein
EXW45_RS22515	COG2333	competence protein COMEC
EXW45_RS22520	COG2131	deaminase
EXW45_RS22525	COG1555	photosystem II stabilization
EXW45_RS22525	COG1596	polysaccharide export
EXW45_RS22530	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW45_RS22535	COG2226	methyltransferase
EXW45_RS22540	COG0799	negative regulation of ribosome biogenesis
EXW45_RS22545	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW45_RS22555	COG1534	Rna-binding protein
EXW45_RS22565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW45_RS22570	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW45_RS22595	COG1595	DNA-templated transcription, initiation
EXW45_RS22605	COG0778	Nitroreductase
EXW45_RS22610	COG2357	RelA SpoT domain protein
EXW45_RS22620	COG1785	Belongs to the alkaline phosphatase family
EXW45_RS22630	COG2267	carboxylic ester hydrolase activity
EXW45_RS22665	COG1404	Belongs to the peptidase S8 family
EXW45_RS22670	COG3186	Phenylalanine-4-hydroxylase
EXW45_RS22680	COG2514	catechol 2,3-dioxygenase activity
EXW45_RS22685	COG2259	Doxx family
EXW45_RS22725	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW45_RS22735	COG1012	belongs to the aldehyde dehydrogenase family
EXW45_RS22735	COG1454	alcohol dehydrogenase
EXW45_RS22740	COG0626	cystathionine gamma-synthase activity
EXW45_RS22745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW45_RS22770	COG0768	penicillin binding
EXW45_RS22785	COG0826	peptidase U32
EXW45_RS22790	COG0826	peptidase U32
EXW45_RS22795	COG4122	O-methyltransferase activity
EXW45_RS22800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW45_RS22810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW45_RS22830	COG0628	permease
EXW45_RS22850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW45_RS22865	COG1104	cysteine desulfurase activity
EXW45_RS22870	COG1959	2 iron, 2 sulfur cluster binding
EXW45_RS22875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW45_RS22885	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW45_RS22910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW45_RS22920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW45_RS22920	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW45_RS22925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW45_RS22930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW45_RS22930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW45_RS22940	COG2244	polysaccharide biosynthetic process
EXW45_RS22945	COG2323	membrane
EXW45_RS22955	COG1862	Preprotein translocase
EXW45_RS22985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW45_RS23015	COG0157	Belongs to the NadC ModD family
EXW45_RS23020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW45_RS23025	COG1104	cysteine desulfurase activity
EXW45_RS23030	COG1827	regulation of RNA biosynthetic process
EXW45_RS23035	COG2258	MOSC domain
EXW45_RS23040	COG0077	Prephenate dehydratase
EXW45_RS23045	COG0577	efflux transmembrane transporter activity
EXW45_RS23050	COG0577	efflux transmembrane transporter activity
EXW45_RS23055	COG1136	(ABC) transporter
EXW45_RS23060	COG5002	protein histidine kinase activity
EXW45_RS23065	COG0745	RESPONSE REGULATOR receiver
EXW45_RS23070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW45_RS23075	COG3290	protein histidine kinase activity
EXW45_RS23085	COG2868	ribosomal protein
EXW45_RS23095	COG1530	ribonuclease E activity
EXW45_RS23100	COG1994	Peptidase M50
EXW45_RS23105	COG0739	heme binding
EXW45_RS23110	COG2894	cell division
EXW45_RS23130	COG1077	Cell shape determining protein MreB Mrl
EXW45_RS23150	COG0285	dihydrofolate synthase activity
EXW45_RS23155	COG0525	valine-tRNA ligase activity
EXW45_RS23165	COG1388	LysM domain
EXW45_RS23175	COG0113	porphobilinogen synthase activity
EXW45_RS23180	COG1587	Uroporphyrinogen-III synthase
EXW45_RS23190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW45_RS23200	COG1846	Transcriptional regulator
EXW45_RS23205	COG1764	response to oxidative stress
EXW45_RS23220	COG1067	ATP-dependent peptidase activity
EXW45_RS23220	COG0470	DNA polymerase III
EXW45_RS23265	COG0622	Phosphoesterase
EXW45_RS23280	COG5401	PFAM Sporulation and spore germination
EXW45_RS23290	COG0477	Major facilitator Superfamily
EXW45_RS23300	COG1309	transcriptional regulator
EXW45_RS23390	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW45_RS23390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW45_RS23440	COG2197	response regulator
EXW45_RS23445	COG2233	PERMEase
EXW45_RS23450	COG0402	S-adenosylhomocysteine deaminase activity
EXW45_RS23455	COG1983	PspC domain protein
EXW45_RS23460	COG1396	sequence-specific DNA binding
EXW45_RS23465	COG0697	spore germination
EXW45_RS23475	COG1959	2 iron, 2 sulfur cluster binding
EXW45_RS23480	COG1668	transmembrane transport
EXW45_RS23485	COG4152	abc transporter atp-binding protein
EXW45_RS23490	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW45_RS23495	COG1360	Flagellar Motor Protein
EXW45_RS23500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW45_RS23505	COG1876	peptidase activity
EXW45_RS23510	COG0824	Thioesterase
EXW45_RS23515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW45_RS23520	COG1053	succinate dehydrogenase
EXW45_RS23525	COG2009	succinate dehydrogenase
EXW45_RS23530	COG1719	4-vinyl reductase, 4VR
EXW45_RS23540	COG3118	belongs to the thioredoxin family
EXW45_RS23545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW45_RS23550	COG2086	electron transfer activity
EXW45_RS23555	COG1024	Enoyl-CoA hydratase
EXW45_RS23560	COG1309	transcriptional regulator
EXW45_RS23565	COG0318	PFAM AMP-dependent synthetase and ligase
EXW45_RS23580	COG2318	DinB family
EXW45_RS23610	COG1131	(ABC) transporter
EXW45_RS23615	COG2205	protein histidine kinase activity
EXW45_RS23620	COG0745	RESPONSE REGULATOR receiver
EXW45_RS23630	COG4895	conserved protein (DUF2196)
EXW45_RS23635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW45_RS23645	COG4509	Sortase family
EXW45_RS23650	COG1120	ATPase activity
EXW45_RS23665	COG5386	Cell surface protein
EXW45_RS23670	COG5386	Cell surface protein
EXW45_RS23675	COG1114	Component of the transport system for branched-chain amino acids
EXW45_RS23680	COG1187	pseudouridine synthase activity
EXW45_RS23690	COG1796	DNA polymerase
EXW45_RS23690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW45_RS23695	COG1286	toxin biosynthetic process
EXW45_RS23740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW45_RS23750	COG1418	mRNA catabolic process
EXW45_RS23785	COG2814	Major facilitator Superfamily
EXW45_RS23790	COG1566	PFAM secretion protein HlyD family protein
EXW45_RS23795	COG1309	transcriptional regulator
EXW45_RS23800	COG1363	Peptidase, m42
EXW45_RS23810	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW45_RS23825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW45_RS23835	COG1484	DNA-dependent DNA replication
EXW45_RS23840	COG3611	Membrane attachment protein
EXW45_RS23850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW45_RS23855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW45_RS23860	COG0237	dephospho-CoA kinase activity
EXW45_RS23865	COG1971	Probably functions as a manganese efflux pump
EXW45_RS23875	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW45_RS23875	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW45_RS23880	COG5002	protein histidine kinase activity
EXW45_RS23885	COG0745	RESPONSE REGULATOR receiver
EXW45_RS23905	COG0538	isocitrate dehydrogenase activity
EXW45_RS23910	COG0372	Belongs to the citrate synthase family
EXW45_RS23920	COG0628	permease
EXW45_RS23925	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW45_RS23950	COG1725	Transcriptional regulator
EXW45_RS23955	COG0281	malic enzyme
EXW45_RS23960	COG0587	DNA-directed DNA polymerase activity
EXW45_RS23975	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW45_RS23990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW45_RS24000	COG4109	DRTGG domain
EXW45_RS24015	COG0006	proline dipeptidase activity
EXW45_RS24055	COG0662	Cupin 2, conserved barrel domain protein
EXW45_RS24065	COG1476	TRANSCRIPTIONal
EXW45_RS24080	COG1028	Short-chain dehydrogenase reductase Sdr
EXW45_RS24085	COG0589	response to stress
EXW45_RS24120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS24145	COG0827	DNA restriction-modification system
EXW45_RS24150	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW45_RS24155	COG3874	Sporulation protein YtfJ
EXW45_RS24170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW45_RS24180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW45_RS24195	COG1104	cysteine desulfurase activity
EXW45_RS24205	COG0583	DNA-binding transcription factor activity
EXW45_RS24210	COG0697	spore germination
EXW45_RS24215	COG1309	transcriptional regulator
EXW45_RS24220	COG1956	GAF domain-containing protein
EXW45_RS24230	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW45_RS24320	COG1595	DNA-templated transcription, initiation
EXW45_RS24330	COG0110	maltose O-acetyltransferase activity
EXW45_RS24335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW45_RS24340	COG0454	-acetyltransferase
EXW45_RS24345	COG0517	IMP dehydrogenase activity
EXW45_RS24350	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW45_RS24370	COG0745	RESPONSE REGULATOR receiver
EXW45_RS24375	COG5002	protein histidine kinase activity
EXW45_RS24380	COG0666	response to abiotic stimulus
EXW45_RS24415	COG1609	Transcriptional regulator
EXW45_RS24425	COG4851	CamS sex pheromone cAM373 precursor
EXW45_RS24430	COG3118	belongs to the thioredoxin family
EXW45_RS24440	COG2309	aminopeptidase activity
EXW45_RS24455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS24460	COG1695	Transcriptional regulator
EXW45_RS24480	COG1674	ftsk spoiiie
EXW45_RS24495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW45_RS24505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW45_RS24510	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW45_RS24515	COG1363	Peptidase, m42
EXW45_RS24525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS24540	COG0510	thiamine kinase activity
EXW45_RS24545	COG1523	belongs to the glycosyl hydrolase 13 family
EXW45_RS24555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW45_RS24560	COG1349	DNA-binding transcription factor activity
EXW45_RS24565	COG1187	pseudouridine synthase activity
EXW45_RS24570	COG2244	polysaccharide biosynthetic process
EXW45_RS24575	COG2081	HI0933 family
EXW45_RS24580	COG2814	Major facilitator Superfamily
EXW45_RS24590	COG3832	glyoxalase III activity
EXW45_RS24610	COG1329	Transcriptional regulator
EXW45_RS24635	COG0314	molybdopterin synthase activity
EXW45_RS24640	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW45_RS24645	COG0303	'Molybdopterin
EXW45_RS24655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW45_RS24660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW45_RS24680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW45_RS24690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW45_RS24730	COG2814	Major facilitator Superfamily
EXW45_RS24735	COG0475	glutathione-regulated potassium exporter activity
EXW45_RS24740	COG0490	domain, Protein
EXW45_RS24745	COG0582	viral genome integration into host DNA
EXW45_RS24755	COG1136	(ABC) transporter
EXW45_RS24775	COG1242	4 iron, 4 sulfur cluster binding
EXW45_RS24780	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW45_RS24785	COG1131	(ABC) transporter
EXW45_RS24795	COG1794	racemase activity, acting on amino acids and derivatives
EXW45_RS24825	COG2267	carboxylic ester hydrolase activity
EXW45_RS24830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW45_RS24835	COG0671	phosphoesterase, PA-phosphatase related
EXW45_RS24840	COG0438	transferase activity, transferring glycosyl groups
EXW45_RS24850	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW45_RS24910	COG5002	protein histidine kinase activity
EXW45_RS24915	COG4191	Histidine kinase
EXW45_RS24925	COG2267	carboxylic ester hydrolase activity
EXW45_RS24945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW45_RS24950	COG1116	anion transmembrane transporter activity
EXW45_RS24955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW45_RS24970	COG0546	phosphoglycolate phosphatase activity
EXW45_RS24980	COG0494	nUDIX hydrolase
EXW45_RS25020	COG1854	S-ribosylhomocysteine lyase activity
EXW45_RS25030	COG0288	reversible hydration of carbon dioxide
EXW45_RS25040	COG1271	oxidase subunit
EXW45_RS25045	COG1294	oxidase, subunit
EXW45_RS25070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS25095	COG1842	Phage shock protein A
EXW45_RS25125	COG5002	protein histidine kinase activity
EXW45_RS25130	COG0745	RESPONSE REGULATOR receiver
EXW45_RS25155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW45_RS25160	COG1597	lipid kinase activity
EXW45_RS25185	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS25190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW45_RS25195	COG0577	efflux transmembrane transporter activity
EXW45_RS25200	COG1136	(ABC) transporter
EXW45_RS25205	COG3708	Transcriptional regulator
EXW45_RS25205	COG2207	Transcriptional regulator
EXW45_RS25210	COG0745	RESPONSE REGULATOR receiver
EXW45_RS25215	COG2205	protein histidine kinase activity
EXW45_RS25220	COG0577	efflux transmembrane transporter activity
EXW45_RS25225	COG0577	efflux transmembrane transporter activity
EXW45_RS25230	COG1136	(ABC) transporter
EXW45_RS25235	COG0577	efflux transmembrane transporter activity
EXW45_RS25255	COG2188	Transcriptional regulator
EXW45_RS25275	COG3964	amidohydrolase
EXW45_RS25295	COG4948	Mandelate Racemase Muconate Lactonizing
EXW45_RS25305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW45_RS25310	COG0596	Alpha beta hydrolase
EXW45_RS25320	COG1169	isochorismate synthase
EXW45_RS25325	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW45_RS25330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW45_RS25335	COG1278	Cold shock
EXW45_RS25350	COG0058	SHG alpha-glucan phosphorylase activity
EXW45_RS25360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW45_RS25370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW45_RS25380	COG1404	Belongs to the peptidase S8 family
EXW45_RS25395	COG1595	DNA-templated transcription, initiation
EXW45_RS25525	COG1285	pathogenesis
EXW45_RS25530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW45_RS25545	COG2155	Conserved Protein
EXW45_RS25550	COG1098	S1 RNA binding domain
EXW45_RS25555	COG0436	Aminotransferase
EXW45_RS25560	COG1522	sequence-specific DNA binding
EXW45_RS25565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW45_RS25570	COG2267	carboxylic ester hydrolase activity
EXW45_RS25580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW45_RS25600	COG5018	Exonuclease
EXW45_RS25605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW45_RS25625	COG2050	protein possibly involved in aromatic compounds catabolism
EXW45_RS25635	COG1268	BioY protein
EXW45_RS25645	COG0297	glycogen (starch) synthase activity
EXW45_RS25660	COG4485	Bacterial membrane protein, YfhO
EXW45_RS25665	COG2246	polysaccharide biosynthetic process
EXW45_RS25670	COG0463	Glycosyl transferase, family 2
EXW45_RS25675	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW45_RS25710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW45_RS25730	COG3584	3D domain protein
EXW45_RS25745	COG1252	NADH dehydrogenase
EXW45_RS25755	COG3708	Transcriptional regulator
EXW45_RS25770	COG1683	Conserved Protein
EXW45_RS25790	COG0316	Belongs to the HesB IscA family
EXW45_RS25805	COG1252	NADH dehydrogenase
EXW45_RS25815	COG2274	protein secretion by the type I secretion system
EXW45_RS25820	COG0390	transport system, permease component
EXW45_RS25825	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW45_RS25845	COG4837	Protein of unknown function (DUF1462)
EXW45_RS25850	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW45_RS25860	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW45_RS25865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW45_RS25875	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW45_RS25885	COG0647	UMP catabolic process
EXW45_RS25895	COG2445	Protein of unknown function DUF86
EXW45_RS25900	COG1494	fructose-1,6-bisphosphatase
EXW45_RS25915	COG4470	Protein conserved in bacteria
EXW45_RS25925	COG0789	Transcriptional regulator
EXW45_RS25930	COG4377	Putative membrane peptidase family (DUF2324)
EXW45_RS25955	COG0739	heme binding
EXW45_RS25965	COG3377	Domain of unknown function (DUF1805)
EXW45_RS25970	COG0737	Belongs to the 5'-nucleotidase family
EXW45_RS25975	COG1695	Transcriptional regulator
EXW45_RS25985	COG0719	Fe-S assembly protein
EXW45_RS25990	COG0822	iron-sulfur transferase activity
EXW45_RS25995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW45_RS26000	COG0719	Fe-S assembly protein
EXW45_RS26005	COG0396	ATPase activity
EXW45_RS26010	COG1464	Belongs to the NlpA lipoprotein family
EXW45_RS26015	COG1464	Belongs to the NlpA lipoprotein family
EXW45_RS26020	COG2011	ABC-type metal ion transport system permease component
EXW45_RS26035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW45_RS26040	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW45_RS26055	COG1393	Belongs to the ArsC family
EXW45_RS26100	COG1309	transcriptional regulator
EXW45_RS26105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW45_RS26110	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS26115	COG0183	Belongs to the thiolase family
EXW45_RS26120	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW45_RS26120	COG1024	Enoyl-CoA hydratase
EXW45_RS26130	COG1686	Belongs to the peptidase S11 family
EXW45_RS26135	COG0506	proline dehydrogenase activity
EXW45_RS26145	COG0011	TIGRFAM Protein of
EXW45_RS26150	COG0840	transmembrane signaling receptor activity
EXW45_RS26170	COG2814	Major facilitator Superfamily
EXW45_RS26175	COG0531	amino acid
EXW45_RS26200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW45_RS26215	COG5002	protein histidine kinase activity
EXW45_RS26220	COG0745	RESPONSE REGULATOR receiver
EXW45_RS26235	COG1131	(ABC) transporter
EXW45_RS26260	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS26270	COG1376	ErfK ybiS ycfS ynhG family protein
EXW45_RS26275	COG0745	RESPONSE REGULATOR receiver
EXW45_RS26280	COG5002	protein histidine kinase activity
EXW45_RS26310	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW45_RS26315	COG3227	Zinc metalloprotease (Elastase)
EXW45_RS26320	COG1741	Belongs to the pirin family
EXW45_RS26335	COG0586	Pfam SNARE associated Golgi protein
EXW45_RS26340	COG0475	glutathione-regulated potassium exporter activity
EXW45_RS26345	COG0490	domain, Protein
EXW45_RS26350	COG1115	amino acid carrier protein
EXW45_RS26355	COG0783	Belongs to the Dps family
EXW45_RS26375	COG1611	Belongs to the LOG family
EXW45_RS26390	COG2311	Membrane
EXW45_RS26395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS26400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS26405	COG1115	amino acid carrier protein
EXW45_RS26410	COG1115	amino acid carrier protein
EXW45_RS26415	COG2910	NAD(P)H-binding
EXW45_RS26430	COG0656	L-ascorbic acid biosynthetic process
EXW45_RS26435	COG2814	Major facilitator Superfamily
EXW45_RS26440	COG1733	regulation of RNA biosynthetic process
EXW45_RS26450	COG1252	NADH dehydrogenase
EXW45_RS26455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EXW45_RS26470	COG3290	protein histidine kinase activity
EXW45_RS26470	COG0840	transmembrane signaling receptor activity
EXW45_RS26480	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW45_RS26505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW45_RS26525	COG1522	sequence-specific DNA binding
EXW45_RS26530	COG0288	reversible hydration of carbon dioxide
EXW45_RS26535	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW45_RS26540	COG2233	PERMEase
EXW45_RS26600	COG0557	exoribonuclease II activity
EXW45_RS26605	COG1647	Serine aminopeptidase, S33
EXW45_RS26610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW45_RS26615	COG1346	cytolysis
EXW45_RS26630	COG0148	phosphopyruvate hydratase activity
EXW45_RS26640	COG0149	triose-phosphate isomerase activity
EXW45_RS26650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW45_RS26665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW45_RS26680	COG5294	Protein conserved in bacteria
EXW45_RS26700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW45_RS26715	COG2323	membrane
EXW45_RS26725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW45_RS26735	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW45_RS26745	COG1051	belongs to the nudix hydrolase family
EXW45_RS26755	COG0492	ferredoxin-NADP+ reductase activity
EXW45_RS26760	COG0457	Tetratricopeptide repeat
EXW45_RS26765	COG0110	maltose O-acetyltransferase activity
EXW45_RS26785	COG1950	PFAM Membrane protein of
EXW45_RS26795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW45_RS26815	COG0789	Transcriptional regulator
EXW45_RS26845	COG0583	DNA-binding transcription factor activity
EXW45_RS26855	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW45_RS26865	COG1132	(ABC) transporter
EXW45_RS26870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW45_RS26875	COG3409	Peptidoglycan-binding domain 1 protein
EXW45_RS26875	COG0793	Belongs to the peptidase S41A family
EXW45_RS26880	COG2177	Part of the ABC transporter FtsEX involved in
EXW45_RS26885	COG2884	Cell division ATP-binding protein ftsE
EXW45_RS26905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXW45_RS26910	COG1278	Cold shock
EXW45_RS26915	COG1040	competence protein
EXW45_RS26920	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW45_RS26925	COG1388	LysM domain
EXW45_RS26925	COG0791	NLP P60 protein
EXW45_RS26930	COG1733	regulation of RNA biosynthetic process
EXW45_RS26935	COG1307	EDD domain protein, DegV family
EXW45_RS26940	COG1739	Uncharacterized protein family UPF0029
EXW45_RS26945	COG1316	TRANSCRIPTIONal
EXW45_RS26950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW45_RS26955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW45_RS26960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW45_RS26970	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW45_RS26970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW45_RS26990	COG1486	melibiose metabolic process
EXW45_RS26995	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW45_RS27000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW45_RS27010	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW45_RS27020	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW45_RS27030	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW45_RS27035	COG1301	dicarboxylic acid transport
EXW45_RS27045	COG0346	lactoylglutathione lyase activity
EXW45_RS27050	COG1511	domain protein
EXW45_RS27055	COG0583	DNA-binding transcription factor activity
EXW45_RS27060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW45_RS27070	COG1271	oxidase subunit
EXW45_RS27075	COG1294	oxidase, subunit
EXW45_RS27080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW45_RS27090	COG1620	l-lactate permease
EXW45_RS27100	COG2389	metal-binding protein
EXW45_RS27110	COG1368	sulfuric ester hydrolase activity
EXW45_RS27120	COG0791	NLP P60 protein
EXW45_RS27120	COG1388	LysM domain
EXW45_RS27125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW45_RS27135	COG1215	transferase activity, transferring glycosyl groups
EXW45_RS27140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW45_RS27145	COG1388	LysM domain
EXW45_RS27145	COG3584	3D domain protein
EXW45_RS27155	COG4715	Zinc finger, swim domain protein
EXW45_RS27160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW45_RS27200	COG0577	efflux transmembrane transporter activity
EXW45_RS27205	COG1136	(ABC) transporter
EXW45_RS27230	COG5002	protein histidine kinase activity
EXW45_RS27235	COG0745	RESPONSE REGULATOR receiver
EXW45_RS27240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW45_RS27255	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW45_RS27260	COG2244	polysaccharide biosynthetic process
EXW45_RS27275	COG1216	Glycosyl transferase, family 2
EXW45_RS27295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW45_RS27300	COG4464	protein tyrosine phosphatase activity
EXW45_RS27305	COG0489	protein tyrosine kinase activity
EXW45_RS27310	COG3944	biosynthesis protein
EXW45_RS27315	COG0489	protein tyrosine kinase activity
EXW45_RS27330	COG1609	Transcriptional regulator
EXW45_RS27340	COG0739	heme binding
EXW45_RS27355	COG3279	Response regulator of the LytR AlgR family
EXW45_RS27365	COG2385	sporulation resulting in formation of a cellular spore
EXW45_RS27380	COG4836	Membrane
EXW45_RS27385	COG1007	ATP synthesis coupled electron transport
EXW45_RS27390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW45_RS27395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW45_RS27405	COG0839	Belongs to the complex I subunit 6 family
EXW45_RS27425	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW45_RS27435	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW45_RS27440	COG5001	Diguanylate cyclase
EXW45_RS27440	COG3300	MHYT domain
EXW45_RS27460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW45_RS27480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW45_RS27490	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW45_RS27525	COG0698	ribose 5-phosphate isomerase
EXW45_RS27535	COG2190	(PTS) system
EXW45_RS27540	COG2259	Doxx family
EXW45_RS27545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW45_RS27560	COG0009	L-threonylcarbamoyladenylate synthase
EXW45_RS27575	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW45_RS27580	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW45_RS27585	COG1435	thymidine kinase activity
EXW45_RS27595	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW45_RS27600	COG1494	fructose-1,6-bisphosphatase
EXW45_RS27620	COG4821	SIS domain
EXW45_RS27625	COG0504	CTP synthase activity
EXW45_RS27640	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS27645	COG1960	acyl-CoA dehydrogenase activity
EXW45_RS27650	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW45_RS27655	COG0183	Belongs to the thiolase family
EXW45_RS27660	COG0247	lactate metabolic process
EXW45_RS27660	COG2181	nitrate reductase activity
EXW45_RS27665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW45_RS27675	COG5001	Diguanylate cyclase
EXW45_RS27675	COG3300	MHYT domain
EXW45_RS27695	COG2197	response regulator
EXW45_RS27700	COG4585	Histidine kinase
EXW45_RS27705	COG0842	Transport permease protein
EXW45_RS27710	COG1131	(ABC) transporter
EXW45_RS27715	COG0024	Methionine aminopeptidase
EXW45_RS27720	COG2234	aminopeptidase activity
EXW45_RS27745	COG1595	DNA-templated transcription, initiation
EXW45_RS27755	COG4506	Protein conserved in bacteria
EXW45_RS27760	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW45_RS27785	COG2814	Major facilitator Superfamily
EXW45_RS27790	COG0789	Transcriptional regulator
EXW45_RS27795	COG0584	glycerophosphoryl diester phosphodiesterase
EXW45_RS27800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW45_RS27810	COG1994	Peptidase M50
EXW45_RS27820	COG1078	dGTPase activity
EXW45_RS27825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW45_RS27830	COG1120	ATPase activity
EXW45_RS27835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS27840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW45_RS27845	COG4844	belongs to the
EXW45_RS27860	COG0280	phosphate acetyltransferase
EXW45_RS27875	COG3773	Cell wall hydrolase
EXW45_RS27885	COG2363	Small membrane protein
EXW45_RS27895	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW45_RS27900	COG2233	PERMEase
EXW45_RS27905	COG0561	phosphatase activity
EXW45_RS27910	COG2814	Major facilitator Superfamily
EXW45_RS27920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW45_RS27925	COG1131	(ABC) transporter
EXW45_RS27930	COG2755	lipolytic protein G-D-S-L family
EXW45_RS27935	COG1609	Transcriptional regulator
EXW45_RS27945	COG0460	homoserine dehydrogenase
EXW45_RS27955	COG2873	o-acetylhomoserine
EXW45_RS27965	COG1011	Hydrolase
EXW45_RS27970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW45_RS27980	COG2197	response regulator
EXW45_RS27985	COG2203	Gaf domain
EXW45_RS27985	COG4585	Histidine kinase
EXW45_RS27990	COG0351	phosphomethylpyrimidine kinase
EXW45_RS27995	COG3706	GGDEF domain
EXW45_RS28000	COG2879	small protein
EXW45_RS28005	COG1966	Carbon starvation protein
EXW45_RS28010	COG3279	Response regulator of the LytR AlgR family
EXW45_RS28015	COG0477	Major facilitator Superfamily
EXW45_RS28040	COG0840	transmembrane signaling receptor activity
EXW45_RS28050	COG1607	acyl-coa hydrolase
EXW45_RS28065	COG0488	(ABC) transporter
EXW45_RS28075	COG1309	transcriptional regulator
EXW45_RS28080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW45_RS28085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW45_RS28085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW45_RS28090	COG0628	permease
EXW45_RS28100	COG1380	Effector of murein hydrolase LrgA
EXW45_RS28105	COG3279	Response regulator of the LytR AlgR family
EXW45_RS28110	COG3275	phosphorelay sensor kinase activity
EXW45_RS28115	COG2814	Major facilitator Superfamily
EXW45_RS28120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW45_RS28125	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW45_RS28130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW45_RS28145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW45_RS28150	COG1272	protein, Hemolysin III
EXW45_RS28170	COG1164	Oligoendopeptidase f
EXW45_RS28190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW45_RS28195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW45_RS28200	COG4853	Protein conserved in bacteria
EXW45_RS28205	COG4863	YycH protein
EXW45_RS28210	COG5002	protein histidine kinase activity
EXW45_RS28215	COG0745	RESPONSE REGULATOR receiver
EXW45_RS28245	COG0305	Participates in initiation and elongation during chromosome replication
EXW45_RS28255	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW45_RS28260	COG4241	membrane
EXW45_RS28270	COG0629	single-stranded DNA binding
EXW45_RS28280	COG0012	GTP binding
EXW45_RS28285	COG4481	Protein conserved in bacteria
EXW45_RS28290	COG0668	transmembrane transport
EXW45_RS28300	COG1475	DNA binding
EXW45_RS28305	COG1192	Involved in chromosome partitioning
EXW45_RS28330	COG1847	R3H domain protein
EXW45_RS28335	COG0706	membrane insertase activity
EXW45_RS28345	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW45_RS28420	COG0582	viral genome integration into host DNA