locus-tag	class	description
EXW48_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW48_RS00015	COG2501	S4 domain
EXW48_RS00025	COG0187	DNA topoisomerase II activity
EXW48_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW48_RS00065	COG0516	GMP reductase activity
EXW48_RS00065	COG0517	IMP dehydrogenase activity
EXW48_RS00070	COG1686	Belongs to the peptidase S11 family
EXW48_RS00100	COG1428	Deoxynucleoside kinase
EXW48_RS00105	COG1428	Deoxynucleoside kinase
EXW48_RS00110	COG1335	isochorismatase
EXW48_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW48_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW48_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW48_RS00190	COG0470	DNA polymerase III
EXW48_RS00195	COG1774	PSP1 C-terminal conserved region
EXW48_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW48_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW48_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW48_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW48_RS00230	COG0084	hydrolase, TatD family'
EXW48_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW48_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW48_RS00250	COG4466	Protein conserved in bacteria
EXW48_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW48_RS00270	COG0251	oxidation-reduction process
EXW48_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW48_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW48_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW48_RS00310	COG2244	polysaccharide biosynthetic process
EXW48_RS00315	COG3956	TIGRFAM MazG family protein
EXW48_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW48_RS00340	COG1098	S1 RNA binding domain
EXW48_RS00355	COG2208	phosphoserine phosphatase activity
EXW48_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW48_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW48_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW48_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW48_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW48_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW48_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW48_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW48_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW48_RS00420	COG1396	sequence-specific DNA binding
EXW48_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW48_RS00515	COG3880	PFAM UvrB UvrC protein
EXW48_RS00525	COG0542	response to heat
EXW48_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW48_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW48_RS00560	COG1045	serine acetyltransferase
EXW48_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW48_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW48_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW48_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW48_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW48_RS00620	COG0222	ribosome binding
EXW48_RS00625	COG2813	Specifically methylates the guanine in position
EXW48_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW48_RS00640	COG1358	cellular component organization or biogenesis
EXW48_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW48_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW48_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW48_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW48_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW48_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW48_RS00760	COG1841	ribosomal large subunit assembly
EXW48_RS00770	COG0201	protein transport
EXW48_RS00780	COG0024	Methionine aminopeptidase
EXW48_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW48_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW48_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW48_RS00855	COG0489	protein tyrosine kinase activity
EXW48_RS00865	COG2194	sulfuric ester hydrolase activity
EXW48_RS00870	COG0726	polysaccharide deacetylase
EXW48_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW48_RS00955	COG4856	YbbR-like protein
EXW48_RS00975	COG1506	peptidase
EXW48_RS00975	COG4946	Tricorn protease homolog
EXW48_RS00975	COG0823	Involved in the tonB-independent uptake of proteins
EXW48_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS01005	COG2011	ABC-type metal ion transport system permease component
EXW48_RS01015	COG1464	Belongs to the NlpA lipoprotein family
EXW48_RS01020	COG0604	alcohol dehydrogenase
EXW48_RS01030	COG0277	FAD linked oxidase domain protein
EXW48_RS01035	COG2271	Major facilitator Superfamily
EXW48_RS01045	COG2814	Major facilitator Superfamily
EXW48_RS01060	COG0601	transmembrane transport
EXW48_RS01065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW48_RS01070	COG0444	Belongs to the ABC transporter superfamily
EXW48_RS01075	COG4608	Belongs to the ABC transporter superfamily
EXW48_RS01080	COG4166	transmembrane transport
EXW48_RS01090	COG2207	Transcriptional regulator
EXW48_RS01100	COG1309	transcriptional regulator
EXW48_RS01110	COG4166	transmembrane transport
EXW48_RS01115	COG4166	transmembrane transport
EXW48_RS01120	COG0656	L-ascorbic acid biosynthetic process
EXW48_RS01135	COG4149	molybdate abc transporter
EXW48_RS01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW48_RS01145	COG1910	domain protein
EXW48_RS01160	COG0697	spore germination
EXW48_RS01175	COG0204	Acyl-transferase
EXW48_RS01185	COG1609	Transcriptional regulator
EXW48_RS01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS01205	COG0084	hydrolase, TatD family'
EXW48_RS01215	COG5298	Protein conserved in bacteria
EXW48_RS01240	COG0488	(ABC) transporter
EXW48_RS01245	COG4585	Histidine kinase
EXW48_RS01250	COG2197	response regulator
EXW48_RS01255	COG1131	(ABC) transporter
EXW48_RS01260	COG0842	Transport permease protein
EXW48_RS01260	COG1511	domain protein
EXW48_RS01265	COG0842	Transport permease protein
EXW48_RS01275	COG0747	negative chemotaxis
EXW48_RS01280	COG0747	negative chemotaxis
EXW48_RS01285	COG0601	transmembrane transport
EXW48_RS01290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW48_RS01295	COG0444	Belongs to the ABC transporter superfamily
EXW48_RS01300	COG4608	Belongs to the ABC transporter superfamily
EXW48_RS01305	COG0561	phosphatase activity
EXW48_RS01335	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW48_RS01340	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW48_RS01350	COG0531	amino acid
EXW48_RS01365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW48_RS01375	COG4294	response to UV
EXW48_RS01380	COG0705	Rhomboid family
EXW48_RS01390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW48_RS01395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW48_RS01400	COG0864	Transcriptional regulator
EXW48_RS01405	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW48_RS01410	COG2183	response to ionizing radiation
EXW48_RS01510	COG0802	atpase or kinase
EXW48_RS01515	COG1214	PFAM Peptidase M22, glycoprotease
EXW48_RS01520	COG0456	acetyltransferase
EXW48_RS01530	COG0488	(ABC) transporter
EXW48_RS01545	COG1266	CAAX protease self-immunity
EXW48_RS01555	COG0459	protein refolding
EXW48_RS01605	COG2252	PERMEase
EXW48_RS01615	COG5002	protein histidine kinase activity
EXW48_RS01640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW48_RS01670	COG2226	methyltransferase
EXW48_RS01680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW48_RS01690	COG1215	transferase activity, transferring glycosyl groups
EXW48_RS01730	COG2205	protein histidine kinase activity
EXW48_RS01735	COG0745	RESPONSE REGULATOR receiver
EXW48_RS01755	COG0697	spore germination
EXW48_RS01775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW48_RS01780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW48_RS01785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW48_RS01795	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW48_RS01810	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW48_RS01820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW48_RS01830	COG0151	Belongs to the GarS family
EXW48_RS01855	COG0210	DNA helicase
EXW48_RS01865	COG4851	CamS sex pheromone cAM373 precursor
EXW48_RS01885	COG1335	isochorismatase
EXW48_RS01895	COG2011	ABC-type metal ion transport system permease component
EXW48_RS01900	COG1464	Belongs to the NlpA lipoprotein family
EXW48_RS01915	COG0003	Pfam Anion-transporting ATPase
EXW48_RS01920	COG1846	Transcriptional regulator
EXW48_RS01925	COG4682	membrane
EXW48_RS01945	COG1597	lipid kinase activity
EXW48_RS01950	COG0546	phosphoglycolate phosphatase activity
EXW48_RS01955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW48_RS01965	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS01970	COG2076	Multidrug Resistance protein
EXW48_RS01975	COG2309	aminopeptidase activity
EXW48_RS01990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS02000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW48_RS02005	COG4807	Protein conserved in bacteria
EXW48_RS02030	COG1757	Na H antiporter
EXW48_RS02035	COG1473	amidohydrolase
EXW48_RS02050	COG0450	alkyl hydroperoxide reductase
EXW48_RS02060	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW48_RS02070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS02075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS02080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS02085	COG0492	ferredoxin-NADP+ reductase activity
EXW48_RS02095	COG0166	Belongs to the GPI family
EXW48_RS02140	COG3541	Predicted nucleotidyltransferase
EXW48_RS02145	COG2814	Major facilitator Superfamily
EXW48_RS02150	COG0723	plastoquinol--plastocyanin reductase activity
EXW48_RS02150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW48_RS02160	COG0765	amino acid transport
EXW48_RS02165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW48_RS02170	COG1126	abc transporter atp-binding protein
EXW48_RS02175	COG0840	transmembrane signaling receptor activity
EXW48_RS02220	COG0366	Alpha amylase catalytic
EXW48_RS02225	COG2190	(PTS) system
EXW48_RS02225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW48_RS02225	COG1263	PTS System
EXW48_RS02255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW48_RS02270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW48_RS02280	COG1116	anion transmembrane transporter activity
EXW48_RS02285	COG0488	(ABC) transporter
EXW48_RS02340	COG2270	Major facilitator Superfamily
EXW48_RS02365	COG4193	domain, Protein
EXW48_RS02375	COG2310	stress, protein
EXW48_RS02380	COG2310	stress, protein
EXW48_RS02385	COG2310	stress, protein
EXW48_RS02390	COG0861	Integral membrane protein TerC family
EXW48_RS02400	COG3853	Toxic anion resistance protein (TelA)
EXW48_RS02415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW48_RS02425	COG1295	ribonuclease BN
EXW48_RS02430	COG2217	Heavy metal translocating P-type atpase
EXW48_RS02435	COG0697	spore germination
EXW48_RS02455	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS02470	COG3871	stress protein (general stress protein 26)
EXW48_RS02475	COG0387	Pfam Sodium calcium exchanger
EXW48_RS02485	COG0535	radical SAM domain protein
EXW48_RS02505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW48_RS02525	COG3829	transcription factor binding
EXW48_RS02535	COG0833	amino acid
EXW48_RS02540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW48_RS02570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW48_RS02570	COG1263	PTS System
EXW48_RS02575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW48_RS02595	COG0463	Glycosyl transferase, family 2
EXW48_RS02605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW48_RS02605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW48_RS02610	COG0463	Glycosyl transferase, family 2
EXW48_RS02620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW48_RS02640	COG1228	amidohydrolase
EXW48_RS02645	COG1090	epimerase
EXW48_RS02675	COG1988	membrane-bound metal-dependent
EXW48_RS02680	COG1194	a g-specific adenine glycosylase
EXW48_RS02710	COG1132	(ABC) transporter
EXW48_RS02715	COG4129	membrane
EXW48_RS02720	COG0069	glutamate synthase activity
EXW48_RS02720	COG0070	glutamate synthase
EXW48_RS02720	COG0067	glutamate synthase
EXW48_RS02730	COG4555	ABC transporter
EXW48_RS02750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW48_RS02755	COG0735	belongs to the Fur family
EXW48_RS02870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW48_RS02875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW48_RS02885	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EXW48_RS02895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW48_RS02905	COG2766	serine protein kinase
EXW48_RS02915	COG2814	Major facilitator Superfamily
EXW48_RS02950	COG2205	protein histidine kinase activity
EXW48_RS02965	COG1136	(ABC) transporter
EXW48_RS02970	COG0577	efflux transmembrane transporter activity
EXW48_RS02975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW48_RS03020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW48_RS03030	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW48_RS03035	COG2268	Band 7 protein
EXW48_RS03045	COG3290	protein histidine kinase activity
EXW48_RS03050	COG4565	transcriptional regulatory protein
EXW48_RS03055	COG2851	Citrate transporter
EXW48_RS03075	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW48_RS03080	COG0745	RESPONSE REGULATOR receiver
EXW48_RS03085	COG5002	protein histidine kinase activity
EXW48_RS03095	COG4990	cell redox homeostasis
EXW48_RS03105	COG3290	protein histidine kinase activity
EXW48_RS03110	COG4565	transcriptional regulatory protein
EXW48_RS03115	COG3493	citrate carrier protein
EXW48_RS03120	COG0281	malic enzyme
EXW48_RS03130	COG0697	spore germination
EXW48_RS03135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS03145	COG5002	protein histidine kinase activity
EXW48_RS03150	COG0745	RESPONSE REGULATOR receiver
EXW48_RS03160	COG0454	-acetyltransferase
EXW48_RS03160	COG0456	acetyltransferase
EXW48_RS03165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW48_RS03170	COG3383	formate dehydrogenase (NAD+) activity
EXW48_RS03175	COG2427	Protein of unknown function (DUF1641)
EXW48_RS03190	COG0531	amino acid
EXW48_RS03195	COG0640	Transcriptional regulator
EXW48_RS03200	COG2217	Heavy metal translocating P-type atpase
EXW48_RS03205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW48_RS03220	COG3227	Zinc metalloprotease (Elastase)
EXW48_RS03240	COG2720	vancomycin resistance protein
EXW48_RS03245	COG1316	TRANSCRIPTIONal
EXW48_RS03250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS03255	COG0346	lactoylglutathione lyase activity
EXW48_RS03260	COG1253	flavin adenine dinucleotide binding
EXW48_RS03265	COG1027	Aspartate ammonia-lyase
EXW48_RS03270	COG1620	l-lactate permease
EXW48_RS03285	COG3104	oligopeptide transport
EXW48_RS03290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS03295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS03300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS03310	COG2226	methyltransferase
EXW48_RS03315	COG0156	8-amino-7-oxononanoate synthase activity
EXW48_RS03320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW48_RS03325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW48_RS03335	COG4548	von Willebrand factor, type A
EXW48_RS03340	COG0714	Associated with various cellular activities
EXW48_RS03345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS03360	COG0531	amino acid
EXW48_RS03365	COG2188	Transcriptional regulator
EXW48_RS03370	COG1263	PTS System
EXW48_RS03370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW48_RS03375	COG0366	Alpha amylase catalytic
EXW48_RS03390	COG0697	spore germination
EXW48_RS03400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW48_RS03405	COG1115	amino acid carrier protein
EXW48_RS03415	COG1126	abc transporter atp-binding protein
EXW48_RS03420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW48_RS03425	COG0765	amino acid transport
EXW48_RS03430	COG0765	amino acid transport
EXW48_RS03435	COG0833	amino acid
EXW48_RS03465	COG2378	regulation of single-species biofilm formation
EXW48_RS03470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW48_RS03480	COG5002	protein histidine kinase activity
EXW48_RS03495	COG0659	secondary active sulfate transmembrane transporter activity
EXW48_RS03520	COG0601	transmembrane transport
EXW48_RS03525	COG4608	Belongs to the ABC transporter superfamily
EXW48_RS03535	COG2271	Major facilitator Superfamily
EXW48_RS03540	COG1846	Transcriptional regulator
EXW48_RS03545	COG0477	Major facilitator Superfamily
EXW48_RS03550	COG1609	Transcriptional regulator
EXW48_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW48_RS03570	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW48_RS03575	COG1879	ABC-type sugar transport system periplasmic component
EXW48_RS03590	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW48_RS03600	COG1063	alcohol dehydrogenase
EXW48_RS03615	COG3568	Endonuclease Exonuclease Phosphatase
EXW48_RS03650	COG0840	transmembrane signaling receptor activity
EXW48_RS03655	COG3584	3D domain protein
EXW48_RS03655	COG3583	domain protein
EXW48_RS03660	COG1476	TRANSCRIPTIONal
EXW48_RS03680	COG3104	oligopeptide transport
EXW48_RS03685	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS03700	COG1113	amino acid transport
EXW48_RS03705	COG2252	PERMEase
EXW48_RS03720	COG2153	protein acetylation
EXW48_RS03735	COG0475	glutathione-regulated potassium exporter activity
EXW48_RS03735	COG0569	domain protein
EXW48_RS03745	COG1845	cytochrome c oxidase, subunit III
EXW48_RS03750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW48_RS03755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW48_RS03760	COG0833	amino acid
EXW48_RS03765	COG4990	cell redox homeostasis
EXW48_RS03780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW48_RS03785	COG0697	spore germination
EXW48_RS03790	COG0531	amino acid
EXW48_RS03805	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW48_RS03810	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW48_RS03815	COG1918	ferrous iron import across plasma membrane
EXW48_RS03815	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW48_RS03820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW48_RS03825	COG0573	inorganic phosphate transmembrane transporter activity
EXW48_RS03830	COG0581	inorganic phosphate transmembrane transporter activity
EXW48_RS03840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW48_RS03960	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW48_RS03980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW48_RS03985	COG1116	anion transmembrane transporter activity
EXW48_RS03990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW48_RS03995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW48_RS04000	COG0352	thiamine-phosphate diphosphorylase activity
EXW48_RS04005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW48_RS04010	COG2104	thiamine diphosphate biosynthetic process
EXW48_RS04020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW48_RS04025	COG0351	phosphomethylpyrimidine kinase
EXW48_RS04065	COG2205	protein histidine kinase activity
EXW48_RS04070	COG2814	Major facilitator Superfamily
EXW48_RS04075	COG1846	Transcriptional regulator
EXW48_RS04085	COG2252	PERMEase
EXW48_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS04150	COG0778	Nitroreductase
EXW48_RS04155	COG2719	SpoVR family
EXW48_RS04185	COG0446	pyridine nucleotide-disulphide oxidoreductase
EXW48_RS04190	COG1937	Protein conserved in bacteria
EXW48_RS04195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS04195	COG0425	Belongs to the sulfur carrier protein TusA family
EXW48_RS04200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS04200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS04205	COG0425	Belongs to the sulfur carrier protein TusA family
EXW48_RS04210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS04210	COG0425	Belongs to the sulfur carrier protein TusA family
EXW48_RS04215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS04220	COG2210	Belongs to the sulfur carrier protein TusA family
EXW48_RS04225	COG0730	response to heat
EXW48_RS04235	COG1316	TRANSCRIPTIONal
EXW48_RS04240	COG0604	alcohol dehydrogenase
EXW48_RS04245	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW48_RS04260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW48_RS04260	COG3711	transcriptional antiterminator
EXW48_RS04265	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW48_RS04270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW48_RS04290	COG1388	LysM domain
EXW48_RS04290	COG3584	3D domain protein
EXW48_RS04295	COG0577	efflux transmembrane transporter activity
EXW48_RS04300	COG1136	(ABC) transporter
EXW48_RS04310	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW48_RS04325	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS04330	COG3546	catalase activity
EXW48_RS04365	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS04400	COG0531	amino acid
EXW48_RS04405	COG0475	glutathione-regulated potassium exporter activity
EXW48_RS04420	COG1737	Transcriptional regulator
EXW48_RS04430	COG1263	PTS System
EXW48_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW48_RS04440	COG2259	Doxx family
EXW48_RS04455	COG0697	spore germination
EXW48_RS04485	COG2076	Multidrug Resistance protein
EXW48_RS04490	COG1309	transcriptional regulator
EXW48_RS04495	COG2814	Major facilitator Superfamily
EXW48_RS04500	COG1733	regulation of RNA biosynthetic process
EXW48_RS04510	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW48_RS04525	COG2211	Major facilitator Superfamily
EXW48_RS04535	COG0693	protein deglycase activity
EXW48_RS04540	COG0753	catalase activity
EXW48_RS04550	COG0531	amino acid
EXW48_RS04555	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS04560	COG1132	(ABC) transporter
EXW48_RS04565	COG1132	(ABC) transporter
EXW48_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW48_RS04575	COG0765	amino acid transport
EXW48_RS04580	COG1126	abc transporter atp-binding protein
EXW48_RS04595	COG0189	ligase activity
EXW48_RS04610	COG3679	Belongs to the UPF0342 family
EXW48_RS04625	COG0028	Belongs to the TPP enzyme family
EXW48_RS04630	COG3527	Alpha-acetolactate decarboxylase
EXW48_RS04640	COG0561	phosphatase activity
EXW48_RS04645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW48_RS04650	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS04665	COG0659	secondary active sulfate transmembrane transporter activity
EXW48_RS04670	COG1024	Enoyl-CoA hydratase
EXW48_RS04690	COG1363	Peptidase, m42
EXW48_RS04910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS04940	COG0519	Catalyzes the synthesis of GMP from XMP
EXW48_RS04960	COG0584	glycerophosphoryl diester phosphodiesterase
EXW48_RS04965	COG0477	Major facilitator Superfamily
EXW48_RS04970	COG3290	protein histidine kinase activity
EXW48_RS04975	COG4565	transcriptional regulatory protein
EXW48_RS04980	COG3181	Tripartite tricarboxylate transporter family receptor
EXW48_RS05005	COG3973	AAA domain
EXW48_RS05035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW48_RS05100	COG0305	Participates in initiation and elongation during chromosome replication
EXW48_RS05205	COG1183	phosphatidylcholine synthase activity
EXW48_RS05220	COG2814	Major facilitator Superfamily
EXW48_RS05225	COG0640	Transcriptional regulator
EXW48_RS05250	COG2376	Dihydroxyacetone kinase
EXW48_RS05260	COG2376	Dihydroxyacetone kinase
EXW48_RS05280	COG0457	Tetratricopeptide repeat
EXW48_RS05290	COG2770	Histidine kinase
EXW48_RS05290	COG3437	response regulator, receiver
EXW48_RS05355	COG3237	CsbD-like
EXW48_RS05380	COG1191	sigma factor activity
EXW48_RS05390	COG2208	phosphoserine phosphatase activity
EXW48_RS05395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW48_RS05440	COG4585	Histidine kinase
EXW48_RS05445	COG2197	response regulator
EXW48_RS05475	COG0420	3'-5' exonuclease activity
EXW48_RS05480	COG4717	serine-type aminopeptidase activity
EXW48_RS05500	COG0745	RESPONSE REGULATOR receiver
EXW48_RS05505	COG2205	protein histidine kinase activity
EXW48_RS05510	COG1136	(ABC) transporter
EXW48_RS05515	COG0577	efflux transmembrane transporter activity
EXW48_RS05535	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS05540	COG0346	lactoylglutathione lyase activity
EXW48_RS05545	COG0346	lactoylglutathione lyase activity
EXW48_RS05550	COG0457	Tetratricopeptide repeat
EXW48_RS05560	COG2267	carboxylic ester hydrolase activity
EXW48_RS05595	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW48_RS05600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW48_RS05610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW48_RS05615	COG1695	Transcriptional regulator
EXW48_RS05625	COG1595	DNA-templated transcription, initiation
EXW48_RS05655	COG0477	Major facilitator Superfamily
EXW48_RS05670	COG3973	AAA domain
EXW48_RS05675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW48_RS05700	COG0537	adenosine 5'-monophosphoramidase activity
EXW48_RS05705	COG1131	(ABC) transporter
EXW48_RS05710	COG4473	ABC transporter
EXW48_RS05725	COG1309	transcriptional regulator
EXW48_RS05735	COG3402	PFAM membrane-flanked domain
EXW48_RS05740	COG3428	Bacterial PH domain
EXW48_RS05780	COG3402	PFAM membrane-flanked domain
EXW48_RS05785	COG3428	Bacterial PH domain
EXW48_RS05790	COG2329	Antibiotic biosynthesis monooxygenase
EXW48_RS05795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW48_RS05810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW48_RS05835	COG1309	transcriptional regulator
EXW48_RS05840	COG1511	domain protein
EXW48_RS05865	COG1609	Transcriptional regulator
EXW48_RS05875	COG1234	tRNA 3'-trailer cleavage
EXW48_RS05880	COG0095	Lipoate-protein ligase
EXW48_RS05890	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS05905	COG1309	transcriptional regulator
EXW48_RS05910	COG1408	metallophosphoesterase
EXW48_RS05915	COG1078	dGTPase activity
EXW48_RS05925	COG0477	Major facilitator Superfamily
EXW48_RS05935	COG1595	DNA-templated transcription, initiation
EXW48_RS05940	COG3708	Transcriptional regulator
EXW48_RS05940	COG2207	Transcriptional regulator
EXW48_RS05945	COG2205	protein histidine kinase activity
EXW48_RS05950	COG0745	RESPONSE REGULATOR receiver
EXW48_RS05965	COG0501	Belongs to the peptidase M48B family
EXW48_RS05970	COG0697	spore germination
EXW48_RS05980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW48_RS05985	COG2224	Isocitrate lyase
EXW48_RS05995	COG1278	Cold shock
EXW48_RS06020	COG0398	Pfam SNARE associated Golgi protein
EXW48_RS06080	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW48_RS06105	COG0367	asparagine synthase
EXW48_RS06115	COG0753	catalase activity
EXW48_RS06120	COG0004	ammonium transporteR
EXW48_RS06145	COG2996	Protein conserved in bacteria
EXW48_RS06165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW48_RS06175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS06190	COG0561	phosphatase activity
EXW48_RS06215	COG2267	carboxylic ester hydrolase activity
EXW48_RS06230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW48_RS06235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW48_RS06240	COG5504	Zn-dependent protease
EXW48_RS06250	COG0180	Tryptophanyl-tRNA synthetase
EXW48_RS06260	COG4166	transmembrane transport
EXW48_RS06265	COG0601	transmembrane transport
EXW48_RS06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW48_RS06275	COG0444	Belongs to the ABC transporter superfamily
EXW48_RS06280	COG4608	Belongs to the ABC transporter superfamily
EXW48_RS06285	COG0534	Mate efflux family protein
EXW48_RS06290	COG4166	transmembrane transport
EXW48_RS06305	COG0861	Integral membrane protein TerC family
EXW48_RS06310	COG4862	establishment of competence for transformation
EXW48_RS06315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS06325	COG1164	Oligoendopeptidase f
EXW48_RS06340	COG2346	COG2346, Truncated hemoglobins
EXW48_RS06345	COG4116	CYTH
EXW48_RS06355	COG2357	RelA SpoT domain protein
EXW48_RS06365	COG0564	pseudouridine synthase activity
EXW48_RS06380	COG0772	Belongs to the SEDS family
EXW48_RS06385	COG1216	Glycosyl transferase, family 2
EXW48_RS06405	COG0463	Glycosyl transferase, family 2
EXW48_RS06405	COG0457	Tetratricopeptide repeat
EXW48_RS06425	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW48_RS06440	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW48_RS06480	COG0210	DNA helicase
EXW48_RS06485	COG2153	protein acetylation
EXW48_RS06495	COG2382	esterase
EXW48_RS06510	COG5492	domain, Protein
EXW48_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW48_RS06525	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW48_RS06525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW48_RS06545	COG0133	tryptophan synthase activity
EXW48_RS06560	COG1620	l-lactate permease
EXW48_RS06565	COG5634	Uncharacterized conserved protein (DUF2278)
EXW48_RS06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW48_RS06630	COG1476	TRANSCRIPTIONal
EXW48_RS06670	COG2226	methyltransferase
EXW48_RS06680	COG1686	Belongs to the peptidase S11 family
EXW48_RS06685	COG0681	Belongs to the peptidase S26 family
EXW48_RS06720	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS06730	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW48_RS06735	COG1177	transmembrane transport
EXW48_RS06750	COG2409	Drug exporters of the RND superfamily
EXW48_RS06760	COG0564	pseudouridine synthase activity
EXW48_RS06770	COG2340	Cysteine-rich secretory protein family
EXW48_RS06775	COG0247	lactate metabolic process
EXW48_RS06780	COG0277	FAD linked oxidase domain protein
EXW48_RS06785	COG3835	regulator
EXW48_RS06795	COG0745	RESPONSE REGULATOR receiver
EXW48_RS06800	COG5002	protein histidine kinase activity
EXW48_RS06805	COG2186	Transcriptional regulator
EXW48_RS06820	COG1556	Lactate utilization protein
EXW48_RS06825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW48_RS06835	COG2116	formate transmembrane transporter activity
EXW48_RS06840	COG0861	Integral membrane protein TerC family
EXW48_RS06845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW48_RS06855	COG2030	dehydratase
EXW48_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS06880	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW48_RS06890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW48_RS06905	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW48_RS06910	COG3842	ATPase activity
EXW48_RS06935	COG1349	DNA-binding transcription factor activity
EXW48_RS06945	COG0235	Class ii aldolase
EXW48_RS06955	COG2861	carbohydrate metabolic process
EXW48_RS06965	COG3852	Histidine kinase
EXW48_RS06970	COG1846	Transcriptional regulator
EXW48_RS06980	COG2318	DinB family
EXW48_RS06985	COG5002	protein histidine kinase activity
EXW48_RS06995	COG0720	synthase
EXW48_RS07010	COG4873	Protein conserved in bacteria
EXW48_RS07040	COG1780	Probably involved in ribonucleotide reductase function
EXW48_RS07055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW48_RS07060	COG1725	Transcriptional regulator
EXW48_RS07065	COG1131	(ABC) transporter
EXW48_RS07095	COG1522	sequence-specific DNA binding
EXW48_RS07105	COG1335	isochorismatase
EXW48_RS07115	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW48_RS07120	COG2070	2-Nitropropane dioxygenase
EXW48_RS07125	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW48_RS07135	COG1696	Membrane protein involved in D-alanine export
EXW48_RS07160	COG0716	FMN binding
EXW48_RS07175	COG3173	Aminoglycoside phosphotransferase
EXW48_RS07195	COG0534	Mate efflux family protein
EXW48_RS07215	COG1846	Transcriptional regulator
EXW48_RS07225	COG1301	dicarboxylic acid transport
EXW48_RS07230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW48_RS07235	COG4709	membrane
EXW48_RS07240	COG3874	Sporulation protein YtfJ
EXW48_RS07265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW48_RS07270	COG0028	Belongs to the TPP enzyme family
EXW48_RS07275	COG0440	acetolactate synthase activity
EXW48_RS07350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW48_RS07365	COG1183	phosphatidylcholine synthase activity
EXW48_RS07370	COG1368	sulfuric ester hydrolase activity
EXW48_RS07380	COG0019	diaminopimelate decarboxylase activity
EXW48_RS07400	COG0529	Catalyzes the synthesis of activated sulfate
EXW48_RS07405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW48_RS07425	COG1648	precorrin-2 dehydrogenase activity
EXW48_RS07430	COG0733	neurotransmitter:sodium symporter activity
EXW48_RS07455	COG1757	Na H antiporter
EXW48_RS07470	COG4758	membrane
EXW48_RS07475	COG4585	Histidine kinase
EXW48_RS07480	COG2197	response regulator
EXW48_RS07490	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS07540	COG0730	response to heat
EXW48_RS07545	COG0306	phosphate transporter
EXW48_RS07550	COG1392	Phosphate transport regulator
EXW48_RS07555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW48_RS07570	COG3852	Histidine kinase
EXW48_RS07575	COG1801	Protein of unknown function DUF72
EXW48_RS07585	COG0582	viral genome integration into host DNA
EXW48_RS07590	COG5002	protein histidine kinase activity
EXW48_RS07605	COG0392	lysyltransferase activity
EXW48_RS07605	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW48_RS07620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW48_RS07625	COG1686	Belongs to the peptidase S11 family
EXW48_RS07630	COG2715	membrane protein required for spore maturation
EXW48_RS07635	COG0700	Nucleoside recognition
EXW48_RS07640	COG1187	pseudouridine synthase activity
EXW48_RS07650	COG1333	cytochrome c biogenesis protein
EXW48_RS07655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW48_RS07660	COG0745	RESPONSE REGULATOR receiver
EXW48_RS07665	COG5002	protein histidine kinase activity
EXW48_RS07670	COG2096	Adenosyltransferase
EXW48_RS07675	COG4942	peptidase
EXW48_RS07685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW48_RS07690	COG1141	Ferredoxin
EXW48_RS07700	COG0514	ATP-dependent DNA helicase (RecQ)
EXW48_RS07705	COG1266	CAAX protease self-immunity
EXW48_RS07715	COG1408	metallophosphoesterase
EXW48_RS07725	COG4862	establishment of competence for transformation
EXW48_RS07730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW48_RS07750	COG0492	ferredoxin-NADP+ reductase activity
EXW48_RS07755	COG0252	asparaginase activity
EXW48_RS07800	COG1160	GTP binding
EXW48_RS07825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW48_RS07840	COG0142	geranyltranstransferase activity
EXW48_RS07850	COG0142	geranyltranstransferase activity
EXW48_RS07875	COG0457	Tetratricopeptide repeat
EXW48_RS07895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW48_RS07900	COG2010	Cytochrome c
EXW48_RS07900	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW48_RS07905	COG4347	Protein of unknown function (DUF1405)
EXW48_RS07920	COG2738	Putative neutral zinc metallopeptidase
EXW48_RS07930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS07935	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW48_RS07955	COG0438	transferase activity, transferring glycosyl groups
EXW48_RS07990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW48_RS07990	COG1199	ATP-dependent helicase activity
EXW48_RS08010	COG3935	DnaD domain protein
EXW48_RS08015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW48_RS08025	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW48_RS08025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW48_RS08085	COG0116	Belongs to the methyltransferase superfamily
EXW48_RS08095	COG1199	ATP-dependent helicase activity
EXW48_RS08100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW48_RS08110	COG0024	Methionine aminopeptidase
EXW48_RS08120	COG2233	PERMEase
EXW48_RS08125	COG2311	Membrane
EXW48_RS08130	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW48_RS08140	COG0456	acetyltransferase
EXW48_RS08195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW48_RS08210	COG0454	-acetyltransferase
EXW48_RS08230	COG0328	RNA-DNA hybrid ribonuclease activity
EXW48_RS08265	COG3403	YqcI/YcgG family
EXW48_RS08270	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS08285	COG3162	membrane
EXW48_RS08290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW48_RS08295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW48_RS08305	COG0475	glutathione-regulated potassium exporter activity
EXW48_RS08310	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW48_RS08315	COG4978	Transcriptional regulator
EXW48_RS08315	COG0789	Transcriptional regulator
EXW48_RS08325	COG2323	membrane
EXW48_RS08340	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW48_RS08375	COG2814	Major facilitator Superfamily
EXW48_RS08395	COG1923	regulation of RNA biosynthetic process
EXW48_RS08405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW48_RS08410	COG1360	Flagellar Motor Protein
EXW48_RS08415	COG2201	protein-glutamate methylesterase activity
EXW48_RS08420	COG0643	Histidine kinase
EXW48_RS08420	COG2198	Histidine kinase
EXW48_RS08425	COG1776	CheC inhibitor of MCP methylation
EXW48_RS08425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW48_RS08440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW48_RS08460	COG1256	bacterial-type flagellum assembly
EXW48_RS08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW48_RS08485	COG1815	bacterial-type flagellum-dependent cell motility
EXW48_RS08490	COG1558	bacterial-type flagellum-dependent cell motility
EXW48_RS08500	COG1766	The M ring may be actively involved in energy transduction
EXW48_RS08505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW48_RS08515	COG1157	protein secretion by the type III secretion system
EXW48_RS08550	COG0835	chemotaxis
EXW48_RS08550	COG0784	Response regulator, receiver
EXW48_RS08560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW48_RS08570	COG0741	lytic transglycosylase activity
EXW48_RS08580	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW48_RS08585	COG1776	CheC inhibitor of MCP methylation
EXW48_RS08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW48_RS08595	COG1338	Plays a role in the flagellum-specific transport system
EXW48_RS08600	COG1987	bacterial-type flagellum assembly
EXW48_RS08610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW48_RS08615	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW48_RS08620	COG1419	protein localization to endoplasmic reticulum
EXW48_RS08625	COG4786	Flagellar basal body rod
EXW48_RS08630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW48_RS08690	COG3764	Sortase (surface protein transpeptidase)
EXW48_RS08695	COG3764	Sortase (surface protein transpeptidase)
EXW48_RS08720	COG0583	DNA-binding transcription factor activity
EXW48_RS08725	COG3842	ATPase activity
EXW48_RS08785	COG0406	alpha-ribazole phosphatase activity
EXW48_RS08805	COG1846	Transcriptional regulator
EXW48_RS08815	COG0367	asparagine synthase
EXW48_RS08845	COG1802	Transcriptional regulator
EXW48_RS08850	COG0697	spore germination
EXW48_RS08855	COG0438	transferase activity, transferring glycosyl groups
EXW48_RS08855	COG1216	Glycosyl transferase, family 2
EXW48_RS08860	COG1757	Na H antiporter
EXW48_RS08870	COG0114	fumarate hydratase activity
EXW48_RS08880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS08890	COG0534	Mate efflux family protein
EXW48_RS08895	COG3340	Belongs to the peptidase S51 family
EXW48_RS08915	COG0785	Cytochrome C biogenesis protein
EXW48_RS08940	COG2733	membrane
EXW48_RS08975	COG1131	(ABC) transporter
EXW48_RS08990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS08995	COG0528	UMP kinase activity
EXW48_RS09005	COG1027	Aspartate ammonia-lyase
EXW48_RS09010	COG0281	malic enzyme
EXW48_RS09015	COG4191	Histidine kinase
EXW48_RS09020	COG0784	Response regulator, receiver
EXW48_RS09025	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW48_RS09080	COG1051	belongs to the nudix hydrolase family
EXW48_RS09085	COG2814	Major facilitator Superfamily
EXW48_RS09110	COG1695	Transcriptional regulator
EXW48_RS09125	COG0477	Major facilitator Superfamily
EXW48_RS09130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW48_RS09140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW48_RS09145	COG4166	transmembrane transport
EXW48_RS09150	COG2223	nitrite transmembrane transporter activity
EXW48_RS09155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW48_RS09170	COG2244	polysaccharide biosynthetic process
EXW48_RS09175	COG0733	neurotransmitter:sodium symporter activity
EXW48_RS09185	COG5566	PFAM Mor transcription activator
EXW48_RS09190	COG2323	membrane
EXW48_RS09210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW48_RS09215	COG2132	Multicopper oxidase
EXW48_RS09225	COG5002	protein histidine kinase activity
EXW48_RS09230	COG0745	RESPONSE REGULATOR receiver
EXW48_RS09240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW48_RS09245	COG0028	Belongs to the TPP enzyme family
EXW48_RS09265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW48_RS09290	COG2814	Major facilitator Superfamily
EXW48_RS09295	COG3384	dioxygenase
EXW48_RS09325	COG3279	Response regulator of the LytR AlgR family
EXW48_RS09330	COG0427	acetyl-CoA hydrolase
EXW48_RS09350	COG4166	transmembrane transport
EXW48_RS09365	COG2264	protein methyltransferase activity
EXW48_RS09375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS09380	COG0745	RESPONSE REGULATOR receiver
EXW48_RS09395	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW48_RS09400	COG1054	Belongs to the UPF0176 family
EXW48_RS09410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW48_RS09415	COG0531	amino acid
EXW48_RS09450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW48_RS09465	COG4257	antibiotic catabolic process
EXW48_RS09470	COG2390	Transcriptional regulator
EXW48_RS09480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS09485	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW48_RS09500	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW48_RS09525	COG0006	proline dipeptidase activity
EXW48_RS09530	COG2132	Multicopper oxidase
EXW48_RS09540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW48_RS09560	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS09570	COG4641	Protein conserved in bacteria
EXW48_RS09580	COG2372	response to copper ion
EXW48_RS09580	COG1276	copper resistance
EXW48_RS09585	COG4549	nuclear export factor GLE1
EXW48_RS09595	COG0697	spore germination
EXW48_RS09600	COG0583	DNA-binding transcription factor activity
EXW48_RS09605	COG1959	2 iron, 2 sulfur cluster binding
EXW48_RS09610	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW48_RS09615	COG0778	Nitroreductase
EXW48_RS09630	COG0628	permease
EXW48_RS09640	COG1231	oxidoreductase activity
EXW48_RS09645	COG0523	cobalamin synthesis protein
EXW48_RS09655	COG0411	ABC transporter
EXW48_RS09675	COG0583	DNA-binding transcription factor activity
EXW48_RS09685	COG1942	4-Oxalocrotonate Tautomerase
EXW48_RS09705	COG1271	oxidase subunit
EXW48_RS09710	COG1294	oxidase, subunit
EXW48_RS09715	COG4988	ABC transporter
EXW48_RS09720	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW48_RS09730	COG1216	Glycosyl transferase, family 2
EXW48_RS09760	COG1686	Belongs to the peptidase S11 family
EXW48_RS09775	COG1388	LysM domain
EXW48_RS09775	COG0791	NLP P60 protein
EXW48_RS09785	COG1132	(ABC) transporter
EXW48_RS09790	COG0745	RESPONSE REGULATOR receiver
EXW48_RS09795	COG5002	protein histidine kinase activity
EXW48_RS09800	COG0300	oxidoreductase activity
EXW48_RS09805	COG4122	O-methyltransferase activity
EXW48_RS09830	COG0460	homoserine dehydrogenase
EXW48_RS09855	COG1316	TRANSCRIPTIONal
EXW48_RS09865	COG0745	RESPONSE REGULATOR receiver
EXW48_RS09870	COG5002	protein histidine kinase activity
EXW48_RS09885	COG1285	pathogenesis
EXW48_RS09890	COG1247	-acetyltransferase
EXW48_RS09920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW48_RS09930	COG1082	Xylose isomerase domain protein TIM barrel
EXW48_RS09940	COG2814	Major facilitator Superfamily
EXW48_RS09945	COG1279	arginine transmembrane transporter activity
EXW48_RS09950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS09960	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW48_RS09995	COG0577	efflux transmembrane transporter activity
EXW48_RS10000	COG2002	toxin-antitoxin pair type II binding
EXW48_RS10005	COG1404	Belongs to the peptidase S8 family
EXW48_RS10010	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW48_RS10025	COG3152	Membrane
EXW48_RS10065	COG3949	Membrane
EXW48_RS10070	COG0783	Belongs to the Dps family
EXW48_RS10085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW48_RS10095	COG1231	oxidoreductase activity
EXW48_RS10100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS10105	COG4989	oxidoreductase activity
EXW48_RS10110	COG0523	cobalamin synthesis protein
EXW48_RS10115	COG0456	acetyltransferase
EXW48_RS10160	COG3443	Belongs to the bacterial solute-binding protein 9 family
EXW48_RS10160	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW48_RS10185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW48_RS10195	COG4166	transmembrane transport
EXW48_RS10220	COG5337	Spore coat protein CotH
EXW48_RS10225	COG1051	belongs to the nudix hydrolase family
EXW48_RS10230	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS10235	COG2244	polysaccharide biosynthetic process
EXW48_RS10245	COG0701	Predicted permease
EXW48_RS10250	COG3689	TIGRFAM TIGR03943 family protein
EXW48_RS10255	COG1607	acyl-coa hydrolase
EXW48_RS10265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS10280	COG0702	epimerase
EXW48_RS10285	COG2839	Protein conserved in bacteria
EXW48_RS10290	COG1253	flavin adenine dinucleotide binding
EXW48_RS10305	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS10310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW48_RS10330	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW48_RS10340	COG1876	peptidase activity
EXW48_RS10350	COG0154	amidase activity
EXW48_RS10355	COG2211	Major facilitator Superfamily
EXW48_RS10375	COG0561	phosphatase activity
EXW48_RS10385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW48_RS10405	COG1819	glycosyl
EXW48_RS10410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS10415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS10430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS10440	COG0456	acetyltransferase
EXW48_RS10475	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW48_RS10575	COG3874	Sporulation protein YtfJ
EXW48_RS10600	COG2226	methyltransferase
EXW48_RS10655	COG0346	lactoylglutathione lyase activity
EXW48_RS10665	COG0604	alcohol dehydrogenase
EXW48_RS10670	COG1595	DNA-templated transcription, initiation
EXW48_RS10700	COG0386	Belongs to the glutathione peroxidase family
EXW48_RS10705	COG1305	Transglutaminase-like
EXW48_RS10710	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW48_RS10715	COG0714	Associated with various cellular activities
EXW48_RS10725	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW48_RS10730	COG1140	nitrate reductase beta subunit
EXW48_RS10735	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW48_RS10740	COG2181	nitrate reductase activity
EXW48_RS10745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW48_RS10750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW48_RS10755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW48_RS10760	COG0303	'Molybdopterin
EXW48_RS10765	COG0314	molybdopterin synthase activity
EXW48_RS10775	COG2223	nitrite transmembrane transporter activity
EXW48_RS10795	COG1648	precorrin-2 dehydrogenase activity
EXW48_RS10805	COG1587	Uroporphyrinogen-III synthase
EXW48_RS10805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW48_RS10810	COG2146	nitrite reductase [NAD(P)H] activity
EXW48_RS10815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW48_RS10820	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW48_RS10855	COG2359	stage V sporulation protein S
EXW48_RS10890	COG1418	mRNA catabolic process
EXW48_RS10895	COG0488	(ABC) transporter
EXW48_RS10910	COG0629	single-stranded DNA binding
EXW48_RS10915	COG1413	lyase activity
EXW48_RS10930	COG2136	Putative SAM-dependent methyltransferase
EXW48_RS10930	COG2521	methyltransferase
EXW48_RS10935	COG0018	arginyl-trna synthetase
EXW48_RS10975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW48_RS10980	COG0017	Asparaginyl-tRNA synthetase
EXW48_RS10985	COG1929	Belongs to the glycerate kinase type-1 family
EXW48_RS10990	COG0471	metal ion transport
EXW48_RS10995	COG0745	RESPONSE REGULATOR receiver
EXW48_RS11000	COG5002	protein histidine kinase activity
EXW48_RS11000	COG3850	Histidine kinase
EXW48_RS11010	COG0733	neurotransmitter:sodium symporter activity
EXW48_RS11035	COG2610	gluconate transmembrane transporter activity
EXW48_RS11040	COG1454	alcohol dehydrogenase
EXW48_RS11045	COG1794	racemase activity, acting on amino acids and derivatives
EXW48_RS11055	COG0456	acetyltransferase
EXW48_RS11060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW48_RS11070	COG1131	(ABC) transporter
EXW48_RS11075	COG4473	ABC transporter
EXW48_RS11085	COG0546	phosphoglycolate phosphatase activity
EXW48_RS11110	COG3250	beta-galactosidase activity
EXW48_RS11125	COG0768	penicillin binding
EXW48_RS11135	COG0204	Acyl-transferase
EXW48_RS11145	COG1272	protein, Hemolysin III
EXW48_RS11155	COG0805	protein transport
EXW48_RS11165	COG1307	EDD domain protein, DegV family
EXW48_RS11175	COG1999	signal sequence binding
EXW48_RS11180	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW48_RS11185	COG0367	asparagine synthase
EXW48_RS11205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS11210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW48_RS11230	COG1335	isochorismatase
EXW48_RS11235	COG1051	belongs to the nudix hydrolase family
EXW48_RS11240	COG0668	transmembrane transport
EXW48_RS11245	COG4585	Histidine kinase
EXW48_RS11245	COG2203	Gaf domain
EXW48_RS11250	COG2197	response regulator
EXW48_RS11255	COG1737	Transcriptional regulator
EXW48_RS11260	COG1064	alcohol dehydrogenase
EXW48_RS11275	COG1070	Carbohydrate kinase
EXW48_RS11285	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW48_RS11325	COG1174	glycine betaine transport
EXW48_RS11360	COG1253	flavin adenine dinucleotide binding
EXW48_RS11365	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS11370	COG5506	Protein of unknown function (DUF1694)
EXW48_RS11385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW48_RS11390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW48_RS11395	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW48_RS11400	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW48_RS11405	COG0456	acetyltransferase
EXW48_RS11410	COG3829	transcription factor binding
EXW48_RS11415	COG1509	lysine 2,3-aminomutase activity
EXW48_RS11450	COG4991	sh3 domain protein
EXW48_RS11450	COG0515	serine threonine protein kinase
EXW48_RS11450	COG3064	Membrane
EXW48_RS11455	COG4326	sporulation control protein
EXW48_RS11460	COG0671	phosphoesterase, PA-phosphatase related
EXW48_RS11465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW48_RS11475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW48_RS11520	COG1595	DNA-templated transcription, initiation
EXW48_RS11555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW48_RS11580	COG0300	oxidoreductase activity
EXW48_RS11600	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW48_RS11600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW48_RS11610	COG2814	Major facilitator Superfamily
EXW48_RS11620	COG0372	Belongs to the citrate synthase family
EXW48_RS11625	COG2079	MmgE PrpD family protein
EXW48_RS11630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW48_RS11635	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS11640	COG2084	Dehydrogenase
EXW48_RS11650	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS11655	COG1024	Enoyl-CoA hydratase
EXW48_RS11670	COG0420	3'-5' exonuclease activity
EXW48_RS11695	COG2223	nitrite transmembrane transporter activity
EXW48_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS11705	COG1169	isochorismate synthase
EXW48_RS11710	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW48_RS11715	COG3433	isochorismatase activity
EXW48_RS11715	COG1535	isochorismatase
EXW48_RS11720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW48_RS11730	COG2814	Major facilitator Superfamily
EXW48_RS11745	COG0776	regulation of translation
EXW48_RS11755	COG2318	DinB family
EXW48_RS11760	COG1115	amino acid carrier protein
EXW48_RS11775	COG2329	Antibiotic biosynthesis monooxygenase
EXW48_RS11780	COG1187	pseudouridine synthase activity
EXW48_RS11785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW48_RS11795	COG1136	(ABC) transporter
EXW48_RS11805	COG0596	Alpha beta hydrolase
EXW48_RS11810	COG2814	Major facilitator Superfamily
EXW48_RS11830	COG0028	Belongs to the TPP enzyme family
EXW48_RS11840	COG2226	methyltransferase
EXW48_RS11850	COG1234	tRNA 3'-trailer cleavage
EXW48_RS11875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW48_RS11885	COG2207	Transcriptional regulator
EXW48_RS11910	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW48_RS11910	COG2755	lipolytic protein G-D-S-L family
EXW48_RS11920	COG5002	protein histidine kinase activity
EXW48_RS11930	COG0745	RESPONSE REGULATOR receiver
EXW48_RS11935	COG5002	protein histidine kinase activity
EXW48_RS11950	COG1846	Transcriptional regulator
EXW48_RS11960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS11990	COG1247	-acetyltransferase
EXW48_RS12015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW48_RS12020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW48_RS12030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS12055	COG0010	Belongs to the arginase family
EXW48_RS12065	COG0583	DNA-binding transcription factor activity
EXW48_RS12070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW48_RS12085	COG0583	DNA-binding transcription factor activity
EXW48_RS12090	COG2258	MOSC domain
EXW48_RS12105	COG1132	(ABC) transporter
EXW48_RS12110	COG1132	(ABC) transporter
EXW48_RS12130	COG1396	sequence-specific DNA binding
EXW48_RS12165	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW48_RS12170	COG1595	DNA-templated transcription, initiation
EXW48_RS12195	COG1649	PFAM Uncharacterised BCR, COG1649
EXW48_RS12220	COG2971	BadF BadG BcrA BcrD
EXW48_RS12250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS12305	COG1309	transcriptional regulator
EXW48_RS12320	COG1136	(ABC) transporter
EXW48_RS12320	COG0577	efflux transmembrane transporter activity
EXW48_RS12330	COG3615	Tellurite resistance protein tehB
EXW48_RS12330	COG0500	methyltransferase
EXW48_RS12340	COG3961	Belongs to the TPP enzyme family
EXW48_RS12370	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW48_RS12380	COG0110	maltose O-acetyltransferase activity
EXW48_RS12385	COG1686	Belongs to the peptidase S11 family
EXW48_RS12400	COG2814	Major facilitator Superfamily
EXW48_RS12440	COG1115	amino acid carrier protein
EXW48_RS12445	COG2066	Belongs to the glutaminase family
EXW48_RS12450	COG4191	Histidine kinase
EXW48_RS12455	COG0784	Response regulator, receiver
EXW48_RS12460	COG0697	spore germination
EXW48_RS12465	COG0531	amino acid
EXW48_RS12480	COG0281	malic enzyme
EXW48_RS12490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW48_RS12495	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS12500	COG0531	amino acid
EXW48_RS12505	COG0322	excinuclease ABC activity
EXW48_RS12520	COG0778	Nitroreductase
EXW48_RS12525	COG0768	penicillin binding
EXW48_RS12530	COG1595	DNA-templated transcription, initiation
EXW48_RS12540	COG0768	penicillin binding
EXW48_RS12545	COG0768	penicillin binding
EXW48_RS12555	COG1609	Transcriptional regulator
EXW48_RS12560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW48_RS12565	COG0561	phosphatase activity
EXW48_RS12570	COG0673	inositol 2-dehydrogenase activity
EXW48_RS12575	COG0738	Major facilitator superfamily
EXW48_RS12615	COG1252	NADH dehydrogenase
EXW48_RS12635	COG1131	(ABC) transporter
EXW48_RS12645	COG1309	transcriptional regulator
EXW48_RS12665	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS12670	COG0439	Biotin carboxylase
EXW48_RS12675	COG0511	ligase activity, forming carbon-carbon bonds
EXW48_RS12680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW48_RS12685	COG1024	Enoyl-CoA hydratase
EXW48_RS12690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW48_RS12695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW48_RS12720	COG2318	DinB family
EXW48_RS12725	COG1686	Belongs to the peptidase S11 family
EXW48_RS12750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW48_RS12785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW48_RS12800	COG2814	Major facilitator Superfamily
EXW48_RS12805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW48_RS12835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW48_RS12850	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW48_RS12865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS12880	COG0693	protein deglycase activity
EXW48_RS12935	COG0825	malonyl-CoA metabolic process
EXW48_RS12945	COG1309	transcriptional regulator
EXW48_RS12950	COG2814	Major facilitator Superfamily
EXW48_RS12960	COG1063	alcohol dehydrogenase
EXW48_RS12970	COG2323	membrane
EXW48_RS12995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW48_RS13000	COG0693	protein deglycase activity
EXW48_RS13010	COG3386	PFAM SMP-30 Gluconolaconase
EXW48_RS13020	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW48_RS13025	COG3773	Cell wall hydrolase
EXW48_RS13035	COG0745	RESPONSE REGULATOR receiver
EXW48_RS13040	COG2205	protein histidine kinase activity
EXW48_RS13055	COG0488	(ABC) transporter
EXW48_RS13065	COG1136	(ABC) transporter
EXW48_RS13070	COG0577	efflux transmembrane transporter activity
EXW48_RS13090	COG0460	homoserine dehydrogenase
EXW48_RS13095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS13105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW48_RS13260	COG2002	toxin-antitoxin pair type II binding
EXW48_RS13340	COG1725	Transcriptional regulator
EXW48_RS13345	COG1131	(ABC) transporter
EXW48_RS13400	COG2124	cytochrome p450
EXW48_RS13445	COG0561	phosphatase activity
EXW48_RS13450	COG5002	protein histidine kinase activity
EXW48_RS13460	COG1819	glycosyl
EXW48_RS13465	COG1794	racemase activity, acting on amino acids and derivatives
EXW48_RS13490	COG2205	protein histidine kinase activity
EXW48_RS13510	COG0745	RESPONSE REGULATOR receiver
EXW48_RS13515	COG5002	protein histidine kinase activity
EXW48_RS13520	COG0604	alcohol dehydrogenase
EXW48_RS13525	COG0671	phosphoesterase, PA-phosphatase related
EXW48_RS13530	COG0768	penicillin binding
EXW48_RS13570	COG0789	Transcriptional regulator
EXW48_RS13575	COG2814	Major facilitator Superfamily
EXW48_RS13590	COG0584	glycerophosphoryl diester phosphodiesterase
EXW48_RS13605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS13610	COG0697	spore germination
EXW48_RS13645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW48_RS13655	COG2223	nitrite transmembrane transporter activity
EXW48_RS13680	COG0592	DNA-directed DNA polymerase activity
EXW48_RS13685	COG1051	belongs to the nudix hydrolase family
EXW48_RS13700	COG0251	oxidation-reduction process
EXW48_RS13705	COG3878	Protein conserved in bacteria
EXW48_RS13730	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW48_RS13770	COG0322	excinuclease ABC activity
EXW48_RS13800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW48_RS13825	COG1011	Hydrolase
EXW48_RS13830	COG0745	RESPONSE REGULATOR receiver
EXW48_RS13835	COG5002	protein histidine kinase activity
EXW48_RS13850	COG1136	(ABC) transporter
EXW48_RS13855	COG0577	efflux transmembrane transporter activity
EXW48_RS13860	COG1073	alpha beta
EXW48_RS13865	COG0657	acetylesterase activity
EXW48_RS13870	COG0076	glutamate decarboxylase activity
EXW48_RS13885	COG1523	belongs to the glycosyl hydrolase 13 family
EXW48_RS13890	COG3227	Zinc metalloprotease (Elastase)
EXW48_RS13895	COG0201	protein transport
EXW48_RS13900	COG0697	spore germination
EXW48_RS13905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS13910	COG0604	alcohol dehydrogenase
EXW48_RS13955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS13970	COG2959	enzyme of heme biosynthesis
EXW48_RS13990	COG3483	tryptophan 2,3-dioxygenase activity
EXW48_RS14005	COG1309	transcriptional regulator
EXW48_RS14020	COG3284	Transcriptional regulator
EXW48_RS14035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS14040	COG1349	DNA-binding transcription factor activity
EXW48_RS14055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW48_RS14060	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW48_RS14065	COG0022	dehydrogenase e1 component
EXW48_RS14070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW48_RS14080	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS14085	COG0456	acetyltransferase
EXW48_RS14085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW48_RS14125	COG4176	ABC-type proline glycine betaine transport system permease component
EXW48_RS14130	COG0517	IMP dehydrogenase activity
EXW48_RS14130	COG4175	Glycine betaine
EXW48_RS14160	COG2153	protein acetylation
EXW48_RS14165	COG3397	chitin binding
EXW48_RS14170	COG1819	glycosyl
EXW48_RS14185	COG2205	protein histidine kinase activity
EXW48_RS14190	COG2226	methyltransferase
EXW48_RS14195	COG2315	Protein conserved in bacteria
EXW48_RS14240	COG3973	AAA domain
EXW48_RS14255	COG0514	ATP-dependent DNA helicase (RecQ)
EXW48_RS14285	COG4824	toxin secretion phage lysis holin
EXW48_RS14305	COG4637	Psort location Cytoplasmic, score
EXW48_RS14330	COG3397	chitin binding
EXW48_RS14335	COG2318	DinB family
EXW48_RS14345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW48_RS14350	COG1115	amino acid carrier protein
EXW48_RS14355	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS14360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW48_RS14370	COG3938	Belongs to the proline racemase family
EXW48_RS14375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW48_RS14415	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS14425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW48_RS14430	COG0519	Catalyzes the synthesis of GMP from XMP
EXW48_RS14435	COG4166	transmembrane transport
EXW48_RS14445	COG4948	Mandelate Racemase Muconate Lactonizing
EXW48_RS14460	COG0667	Aldo Keto reductase
EXW48_RS14490	COG2226	methyltransferase
EXW48_RS14495	COG2936	dipeptidyl-peptidase activity
EXW48_RS14500	COG5002	protein histidine kinase activity
EXW48_RS14505	COG0745	RESPONSE REGULATOR receiver
EXW48_RS14545	COG1164	Oligoendopeptidase f
EXW48_RS14550	COG0531	amino acid
EXW48_RS14555	COG1522	sequence-specific DNA binding
EXW48_RS14570	COG1307	EDD domain protein, DegV family
EXW48_RS14615	COG2814	Major facilitator Superfamily
EXW48_RS14625	COG1664	Polymer-forming cytoskeletal
EXW48_RS14630	COG0789	Transcriptional regulator
EXW48_RS14635	COG4533	DNA binding
EXW48_RS14640	COG0477	Major facilitator Superfamily
EXW48_RS14640	COG2814	Major facilitator Superfamily
EXW48_RS14660	COG2261	transglycosylase associated protein
EXW48_RS14675	COG1073	alpha beta
EXW48_RS14675	COG2226	methyltransferase
EXW48_RS14700	COG0436	Aminotransferase
EXW48_RS14705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW48_RS14730	COG1131	(ABC) transporter
EXW48_RS14775	COG0628	permease
EXW48_RS14785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW48_RS14790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW48_RS14795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW48_RS14825	COG2816	NAD+ diphosphatase activity
EXW48_RS14845	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW48_RS14870	COG0697	spore germination
EXW48_RS14875	COG2318	DinB family
EXW48_RS14905	COG0346	lactoylglutathione lyase activity
EXW48_RS14920	COG0861	Integral membrane protein TerC family
EXW48_RS14925	COG1368	sulfuric ester hydrolase activity
EXW48_RS14930	COG0488	(ABC) transporter
EXW48_RS14940	COG1033	growth of symbiont in host cell
EXW48_RS14940	COG2409	Drug exporters of the RND superfamily
EXW48_RS14945	COG1309	transcriptional regulator
EXW48_RS14960	COG0287	Prephenate dehydrogenase
EXW48_RS14975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW48_RS14975	COG1605	Chorismate mutase
EXW48_RS15010	COG1388	LysM domain
EXW48_RS15010	COG3584	3D domain protein
EXW48_RS15020	COG0346	lactoylglutathione lyase activity
EXW48_RS15040	COG2390	Transcriptional regulator
EXW48_RS15045	COG1070	Carbohydrate kinase
EXW48_RS15075	COG2329	Antibiotic biosynthesis monooxygenase
EXW48_RS15090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS15095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW48_RS15105	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW48_RS15110	COG4187	Peptidase family M20/M25/M40
EXW48_RS15115	COG1414	Transcriptional regulator
EXW48_RS15120	COG0833	amino acid
EXW48_RS15130	COG1690	Belongs to the RtcB family
EXW48_RS15135	COG3239	Fatty acid desaturase
EXW48_RS15145	COG1785	Belongs to the alkaline phosphatase family
EXW48_RS15155	COG3655	Transcriptional regulator
EXW48_RS15170	COG4377	Putative membrane peptidase family (DUF2324)
EXW48_RS15180	COG3279	Response regulator of the LytR AlgR family
EXW48_RS15195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS15200	COG0346	lactoylglutathione lyase activity
EXW48_RS15220	COG0714	Associated with various cellular activities
EXW48_RS15275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW48_RS15280	COG0753	catalase activity
EXW48_RS15300	COG0583	DNA-binding transcription factor activity
EXW48_RS15310	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS15340	COG0714	Associated with various cellular activities
EXW48_RS15405	COG0778	Nitroreductase
EXW48_RS15410	COG1846	Transcriptional regulator
EXW48_RS15435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW48_RS15440	COG1136	(ABC) transporter
EXW48_RS15470	COG0456	acetyltransferase
EXW48_RS15490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS15530	COG0730	response to heat
EXW48_RS15540	COG0833	amino acid
EXW48_RS15550	COG4335	DNA alkylation repair
EXW48_RS15565	COG0384	phenazine biosynthesis protein PhzF
EXW48_RS15580	COG0768	penicillin binding
EXW48_RS15610	COG1984	allophanate hydrolase subunit 2
EXW48_RS15615	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW48_RS15620	COG1414	Transcriptional regulator
EXW48_RS15635	COG3142	Participates in the control of copper homeostasis
EXW48_RS15640	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW48_RS15645	COG0640	Transcriptional regulator
EXW48_RS15655	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS15670	COG3314	Sporulation integral membrane protein YlbJ
EXW48_RS15700	COG3848	Pyruvate phosphate dikinase
EXW48_RS15700	COG0574	Belongs to the PEP-utilizing enzyme family
EXW48_RS15705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS15720	COG5577	PFAM Coat F domain
EXW48_RS15725	COG3403	YqcI/YcgG family
EXW48_RS15730	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS15735	COG1113	amino acid transport
EXW48_RS15765	COG1063	alcohol dehydrogenase
EXW48_RS15780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW48_RS15790	COG1525	nuclease
EXW48_RS15790	COG0737	Belongs to the 5'-nucleotidase family
EXW48_RS15790	COG4085	toxin activity
EXW48_RS15795	COG2267	carboxylic ester hydrolase activity
EXW48_RS15800	COG1335	isochorismatase
EXW48_RS15825	COG0583	DNA-binding transcription factor activity
EXW48_RS15885	COG0598	Magnesium transport protein CorA
EXW48_RS15930	COG0415	Belongs to the DNA photolyase family
EXW48_RS15935	COG0288	reversible hydration of carbon dioxide
EXW48_RS15945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW48_RS15950	COG5609	conserved protein (DUF2294)
EXW48_RS15975	COG1329	Transcriptional regulator
EXW48_RS15990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS15995	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW48_RS16020	COG2211	Major facilitator Superfamily
EXW48_RS16035	COG4641	Protein conserved in bacteria
EXW48_RS16055	COG0798	PFAM Bile acid sodium symporter
EXW48_RS16060	COG0346	lactoylglutathione lyase activity
EXW48_RS16065	COG0640	Transcriptional regulator
EXW48_RS16115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW48_RS16115	COG3320	Male sterility
EXW48_RS16130	COG0346	lactoylglutathione lyase activity
EXW48_RS16170	COG2814	Major facilitator Superfamily
EXW48_RS16180	COG4895	conserved protein (DUF2196)
EXW48_RS16280	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW48_RS16310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW48_RS16320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW48_RS16340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW48_RS16355	COG1136	(ABC) transporter
EXW48_RS16360	COG0577	efflux transmembrane transporter activity
EXW48_RS16380	COG5002	protein histidine kinase activity
EXW48_RS16380	COG3850	Histidine kinase
EXW48_RS16390	COG2364	Membrane
EXW48_RS16395	COG1846	Transcriptional regulator
EXW48_RS16400	COG0456	acetyltransferase
EXW48_RS16405	COG2808	Putative FMN-binding domain
EXW48_RS16410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS16435	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW48_RS16460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW48_RS16495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW48_RS16535	COG2814	Major facilitator Superfamily
EXW48_RS16745	COG4282	regulation of fungal-type cell wall biogenesis
EXW48_RS16925	COG0477	Major facilitator Superfamily
EXW48_RS16940	COG1846	Transcriptional regulator
EXW48_RS16945	COG2814	Major facilitator Superfamily
EXW48_RS16955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW48_RS16960	COG1131	(ABC) transporter
EXW48_RS16985	COG2031	fatty acid transporter
EXW48_RS16995	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW48_RS17030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW48_RS17050	COG1288	antiporter activity
EXW48_RS17055	COG2356	endonuclease I
EXW48_RS17060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW48_RS17120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW48_RS17150	COG0583	DNA-binding transcription factor activity
EXW48_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS17180	COG1131	(ABC) transporter
EXW48_RS17205	COG1011	Hydrolase
EXW48_RS17215	COG2365	Tyrosine phosphatase family
EXW48_RS17250	COG0346	lactoylglutathione lyase activity
EXW48_RS17255	COG1940	carbohydrate kinase activity
EXW48_RS17260	COG0110	maltose O-acetyltransferase activity
EXW48_RS17275	COG0628	permease
EXW48_RS17295	COG1720	tRNA m6t6A37 methyltransferase activity
EXW48_RS17300	COG0500	methyltransferase
EXW48_RS17310	COG0477	Major facilitator Superfamily
EXW48_RS17330	COG0640	Transcriptional regulator
EXW48_RS17385	COG1253	flavin adenine dinucleotide binding
EXW48_RS17390	COG0789	Transcriptional regulator
EXW48_RS17400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW48_RS17425	COG0697	spore germination
EXW48_RS17430	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW48_RS17435	COG3813	Protein conserved in bacteria
EXW48_RS17440	COG2706	6-phosphogluconolactonase activity
EXW48_RS17445	COG1070	Carbohydrate kinase
EXW48_RS17455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EXW48_RS17460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW48_RS17470	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW48_RS17485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW48_RS17495	COG0604	alcohol dehydrogenase
EXW48_RS17495	COG3321	synthase
EXW48_RS17510	COG0656	L-ascorbic acid biosynthetic process
EXW48_RS17540	COG0814	amino acid
EXW48_RS17565	COG1393	Belongs to the ArsC family
EXW48_RS17570	COG1733	regulation of RNA biosynthetic process
EXW48_RS17575	COG2188	Transcriptional regulator
EXW48_RS17580	COG0673	inositol 2-dehydrogenase activity
EXW48_RS17600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS17620	COG0384	phenazine biosynthesis protein PhzF
EXW48_RS17630	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS17645	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW48_RS17650	COG1733	regulation of RNA biosynthetic process
EXW48_RS17670	COG1191	sigma factor activity
EXW48_RS17680	COG1280	lysine exporter protein (LysE YggA)
EXW48_RS17720	COG1151	hydroxylamine reductase activity
EXW48_RS17730	COG3409	Peptidoglycan-binding domain 1 protein
EXW48_RS17730	COG3757	hydrolase, family 25
EXW48_RS17765	COG2072	flavoprotein involved in K transport
EXW48_RS17810	COG1695	Transcriptional regulator
EXW48_RS17815	COG0604	alcohol dehydrogenase
EXW48_RS17820	COG1113	amino acid transport
EXW48_RS17825	COG2814	Major facilitator Superfamily
EXW48_RS17855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW48_RS17860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW48_RS17875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS17880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS17885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS17890	COG3739	integral membrane protein
EXW48_RS17925	COG0583	DNA-binding transcription factor activity
EXW48_RS17950	COG1193	negative regulation of DNA recombination
EXW48_RS17970	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW48_RS17975	COG1164	Oligoendopeptidase f
EXW48_RS17980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW48_RS18005	COG0584	glycerophosphoryl diester phosphodiesterase
EXW48_RS18015	COG0640	Transcriptional regulator
EXW48_RS18020	COG0604	alcohol dehydrogenase
EXW48_RS18030	COG0457	Tetratricopeptide repeat
EXW48_RS18040	COG2808	Putative FMN-binding domain
EXW48_RS18045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW48_RS18055	COG0385	Bile acid
EXW48_RS18060	COG0277	FAD linked oxidase domain protein
EXW48_RS18075	COG3300	MHYT domain
EXW48_RS18075	COG5001	Diguanylate cyclase
EXW48_RS18080	COG0488	(ABC) transporter
EXW48_RS18085	COG1309	transcriptional regulator
EXW48_RS18125	COG1285	pathogenesis
EXW48_RS18135	COG2514	catechol 2,3-dioxygenase activity
EXW48_RS18140	COG2720	vancomycin resistance protein
EXW48_RS18165	COG1278	Cold shock
EXW48_RS18175	COG0716	FMN binding
EXW48_RS18205	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS18215	COG0165	Argininosuccinate lyase
EXW48_RS18230	COG4145	pantothenate transmembrane transporter activity
EXW48_RS18240	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS18255	COG1657	PFAM Prenyltransferase squalene oxidase
EXW48_RS18260	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW48_RS18265	COG2962	Rard protein
EXW48_RS18270	COG3326	Membrane
EXW48_RS18285	COG0489	protein tyrosine kinase activity
EXW48_RS18295	COG0314	molybdopterin synthase activity
EXW48_RS18300	COG0303	'Molybdopterin
EXW48_RS18305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW48_RS18310	COG2116	formate transmembrane transporter activity
EXW48_RS18320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW48_RS18325	COG5609	conserved protein (DUF2294)
EXW48_RS18330	COG2427	Protein of unknown function (DUF1641)
EXW48_RS18335	COG3383	formate dehydrogenase (NAD+) activity
EXW48_RS18340	COG0697	spore germination
EXW48_RS18385	COG2226	methyltransferase
EXW48_RS18390	COG4166	transmembrane transport
EXW48_RS18395	COG4166	transmembrane transport
EXW48_RS18400	COG4166	transmembrane transport
EXW48_RS18405	COG1301	dicarboxylic acid transport
EXW48_RS18410	COG1316	TRANSCRIPTIONal
EXW48_RS18420	COG1595	DNA-templated transcription, initiation
EXW48_RS18435	COG1131	(ABC) transporter
EXW48_RS18460	COG0673	inositol 2-dehydrogenase activity
EXW48_RS18465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW48_RS18470	COG0187	DNA topoisomerase II activity
EXW48_RS18475	COG1832	CoA-binding protein
EXW48_RS18480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW48_RS18485	COG0745	RESPONSE REGULATOR receiver
EXW48_RS18505	COG4841	protein insertion into membrane
EXW48_RS18510	COG0824	Thioesterase
EXW48_RS18535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW48_RS18545	COG2274	protein secretion by the type I secretion system
EXW48_RS18550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW48_RS18580	COG2211	Major facilitator Superfamily
EXW48_RS18590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW48_RS18615	COG0183	Belongs to the thiolase family
EXW48_RS18620	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS18625	COG1268	BioY protein
EXW48_RS18630	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS18645	COG1396	sequence-specific DNA binding
EXW48_RS18690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS18700	COG5002	protein histidine kinase activity
EXW48_RS18705	COG0400	carboxylic ester hydrolase activity
EXW48_RS18710	COG0346	lactoylglutathione lyase activity
EXW48_RS18715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW48_RS18725	COG0069	glutamate synthase activity
EXW48_RS18730	COG1902	pentaerythritol trinitrate reductase activity
EXW48_RS18735	COG1329	Transcriptional regulator
EXW48_RS18740	COG0010	Belongs to the arginase family
EXW48_RS18765	COG2226	methyltransferase
EXW48_RS18805	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW48_RS18810	COG0785	Cytochrome C biogenesis protein
EXW48_RS18820	COG1473	amidohydrolase
EXW48_RS18830	COG1131	(ABC) transporter
EXW48_RS18845	COG0583	DNA-binding transcription factor activity
EXW48_RS18855	COG1346	cytolysis
EXW48_RS18870	COG0730	response to heat
EXW48_RS18895	COG1132	(ABC) transporter
EXW48_RS18900	COG1132	(ABC) transporter
EXW48_RS18905	COG3763	UPF0154 protein
EXW48_RS18940	COG3639	organic phosphonate transmembrane transporter activity
EXW48_RS18950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW48_RS18955	COG0737	Belongs to the 5'-nucleotidase family
EXW48_RS18965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW48_RS18985	COG1695	Transcriptional regulator
EXW48_RS18990	COG0174	glutamine synthetase
EXW48_RS18995	COG0789	Transcriptional regulator
EXW48_RS19000	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW48_RS19005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW48_RS19010	COG2860	membrane
EXW48_RS19020	COG0464	growth
EXW48_RS19050	COG3584	3D domain protein
EXW48_RS19050	COG1388	LysM domain
EXW48_RS19055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW48_RS19055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW48_RS19055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW48_RS19060	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW48_RS19065	COG1349	DNA-binding transcription factor activity
EXW48_RS19070	COG1979	alcohol dehydrogenase
EXW48_RS19075	COG2322	membrane
EXW48_RS19085	COG1113	amino acid transport
EXW48_RS19095	COG1408	metallophosphoesterase
EXW48_RS19100	COG2116	formate transmembrane transporter activity
EXW48_RS19115	COG2217	Heavy metal translocating P-type atpase
EXW48_RS19120	COG2608	mercury ion transmembrane transporter activity
EXW48_RS19125	COG1937	Protein conserved in bacteria
EXW48_RS19135	COG2819	hydrolase of the alpha beta superfamily
EXW48_RS19140	COG1120	ATPase activity
EXW48_RS19145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS19150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS19155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS19160	COG0708	Exodeoxyribonuclease III
EXW48_RS19165	COG2169	Transcriptional regulator
EXW48_RS19170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW48_RS19175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW48_RS19185	COG2364	Membrane
EXW48_RS19200	COG2267	carboxylic ester hydrolase activity
EXW48_RS19205	COG3300	MHYT domain
EXW48_RS19205	COG5001	Diguanylate cyclase
EXW48_RS19245	COG1346	cytolysis
EXW48_RS19250	COG1380	Effector of murein hydrolase LrgA
EXW48_RS19255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW48_RS19265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW48_RS19275	COG2188	Transcriptional regulator
EXW48_RS19280	COG2723	6-phospho-beta-galactosidase activity
EXW48_RS19285	COG0840	transmembrane signaling receptor activity
EXW48_RS19295	COG1404	Belongs to the peptidase S8 family
EXW48_RS19300	COG3773	Cell wall hydrolase
EXW48_RS19310	COG1368	sulfuric ester hydrolase activity
EXW48_RS19315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW48_RS19325	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW48_RS19335	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW48_RS19345	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW48_RS19355	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW48_RS19360	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW48_RS19360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW48_RS19370	COG2359	stage V sporulation protein S
EXW48_RS19375	COG1692	metallophosphoesterase
EXW48_RS19405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW48_RS19410	COG1426	Protein conserved in bacteria
EXW48_RS19425	COG0300	oxidoreductase activity
EXW48_RS19430	COG0612	Peptidase, M16
EXW48_RS19435	COG0612	Peptidase, M16
EXW48_RS19440	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW48_RS19445	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW48_RS19450	COG3845	ABC transporter
EXW48_RS19455	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW48_RS19460	COG2188	Transcriptional regulator
EXW48_RS19465	COG1674	ftsk spoiiie
EXW48_RS19475	COG0740	serine-type endopeptidase activity
EXW48_RS19480	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW48_RS19490	COG0527	aspartate kinase activity
EXW48_RS19495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW48_RS19520	COG4824	toxin secretion phage lysis holin
EXW48_RS19625	COG0582	viral genome integration into host DNA
EXW48_RS19635	COG0791	NLP P60 protein
EXW48_RS19635	COG1388	LysM domain
EXW48_RS19640	COG3583	domain protein
EXW48_RS19640	COG3584	3D domain protein
EXW48_RS19660	COG0305	Participates in initiation and elongation during chromosome replication
EXW48_RS19690	COG1396	sequence-specific DNA binding
EXW48_RS19710	COG2856	Zn peptidase
EXW48_RS19725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW48_RS19730	COG1873	PFAM PRC-barrel domain
EXW48_RS19735	COG0612	Peptidase, M16
EXW48_RS19740	COG0726	polysaccharide deacetylase
EXW48_RS19755	COG0196	riboflavin kinase activity
EXW48_RS19770	COG1550	Protein conserved in bacteria
EXW48_RS19780	COG1358	cellular component organization or biogenesis
EXW48_RS19785	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW48_RS19790	COG0195	Participates in both transcription termination and antitermination
EXW48_RS19810	COG0750	zinc metalloprotease
EXW48_RS19820	COG4589	Belongs to the CDS family
EXW48_RS19830	COG0233	cytoplasmic translational termination
EXW48_RS19840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW48_RS19865	COG4974	Belongs to the 'phage' integrase family
EXW48_RS19875	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW48_RS19880	COG0758	DNA mediated transformation
EXW48_RS19885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW48_RS19925	COG1837	Belongs to the UPF0109 family
EXW48_RS19935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW48_RS19945	COG0552	protein localization to endoplasmic reticulum
EXW48_RS19950	COG1196	nuclear chromosome segregation
EXW48_RS19960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW48_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS19970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW48_RS19985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW48_RS19990	COG1461	Dihydroxyacetone kinase
EXW48_RS19995	COG1302	Protein conserved in bacteria
EXW48_RS20010	COG1564	THIamine pyrophosphokinase
EXW48_RS20015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW48_RS20025	COG0515	serine threonine protein kinase
EXW48_RS20025	COG2815	serine threonine protein kinase
EXW48_RS20030	COG0631	protein serine/threonine phosphatase activity
EXW48_RS20035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW48_RS20040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW48_RS20040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW48_RS20050	COG0242	peptide deformylase activity
EXW48_RS20055	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW48_RS20060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW48_RS20065	COG1758	RNA polymerase activity
EXW48_RS20080	COG1561	YicC-like family, N-terminal region
EXW48_RS20085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW48_RS20095	COG0006	proline dipeptidase activity
EXW48_RS20115	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW48_RS20140	COG0543	2 iron, 2 sulfur cluster binding
EXW48_RS20175	COG0564	pseudouridine synthase activity
EXW48_RS20195	COG3599	regulation of cell shape
EXW48_RS20200	COG2302	S4 RNA-binding domain
EXW48_RS20205	COG0762	integral membrane protein
EXW48_RS20215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW48_RS20225	COG1873	PFAM PRC-barrel domain
EXW48_RS20230	COG1191	sigma factor activity
EXW48_RS20235	COG1191	sigma factor activity
EXW48_RS20245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW48_RS20250	COG0849	cell division
EXW48_RS20255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW48_RS20270	COG0772	Belongs to the SEDS family
EXW48_RS20285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW48_RS20290	COG0768	penicillin binding
EXW48_RS20295	COG0768	penicillin binding
EXW48_RS20300	COG4839	cell division protein FtsL
EXW48_RS20315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW48_RS20330	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW48_RS20335	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW48_RS20345	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW48_RS20350	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW48_RS20355	COG3314	Sporulation integral membrane protein YlbJ
EXW48_RS20365	COG0742	ribosomal rna small subunit methyltransferase
EXW48_RS20380	COG3679	Belongs to the UPF0342 family
EXW48_RS20385	COG0406	alpha-ribazole phosphatase activity
EXW48_RS20400	COG2340	Cysteine-rich secretory protein family
EXW48_RS20415	COG3336	cytochrome c oxidase
EXW48_RS20430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW48_RS20450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW48_RS20455	COG0772	Belongs to the SEDS family
EXW48_RS20460	COG4838	Belongs to the UPF0358 family
EXW48_RS20465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW48_RS20470	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW48_RS20480	COG4896	Protein conserved in bacteria
EXW48_RS20495	COG1217	gtp-binding protein TYPA
EXW48_RS20505	COG0483	inositol monophosphate 1-phosphatase activity
EXW48_RS20525	COG1982	Orn Lys Arg decarboxylase major
EXW48_RS20575	COG0022	dehydrogenase e1 component
EXW48_RS20580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW48_RS20595	COG0561	phosphatase activity
EXW48_RS20605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW48_RS20610	COG0569	domain protein
EXW48_RS20625	COG2171	N-acyltransferase activity
EXW48_RS20630	COG0583	DNA-binding transcription factor activity
EXW48_RS20635	COG0517	IMP dehydrogenase activity
EXW48_RS20645	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW48_RS20655	COG4703	Protein of unknown function (DUF1797)
EXW48_RS20670	COG2200	EAL domain
EXW48_RS20675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS20680	COG1408	metallophosphoesterase
EXW48_RS20690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EXW48_RS20725	COG2814	Major facilitator Superfamily
EXW48_RS20750	COG3209	COG3209 Rhs family protein
EXW48_RS20760	COG2205	protein histidine kinase activity
EXW48_RS20770	COG0436	Aminotransferase
EXW48_RS20775	COG1609	Transcriptional regulator
EXW48_RS20780	COG3833	ABC-type maltose transport systems, permease component
EXW48_RS20785	COG1175	transmembrane transport
EXW48_RS20790	COG2182	Extracellular solute-binding protein
EXW48_RS20800	COG0366	Alpha amylase catalytic
EXW48_RS20805	COG3842	ATPase activity
EXW48_RS20850	COG0183	Belongs to the thiolase family
EXW48_RS20880	COG1695	Transcriptional regulator
EXW48_RS20885	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS20905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW48_RS20910	COG0436	Aminotransferase
EXW48_RS20945	COG2084	Dehydrogenase
EXW48_RS20955	COG2199	diguanylate cyclase activity
EXW48_RS20960	COG0778	Nitroreductase
EXW48_RS20985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW48_RS20985	COG2190	(PTS) system
EXW48_RS20985	COG1263	PTS System
EXW48_RS20990	COG3711	transcriptional antiterminator
EXW48_RS21000	COG2188	Transcriptional regulator
EXW48_RS21010	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW48_RS21035	COG1547	Domain of unknown function (DUF309)
EXW48_RS21040	COG0456	acetyltransferase
EXW48_RS21045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW48_RS21050	COG4086	secreted protein
EXW48_RS21055	COG0561	phosphatase activity
EXW48_RS21060	COG0697	spore germination
EXW48_RS21075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW48_RS21100	COG0733	neurotransmitter:sodium symporter activity
EXW48_RS21120	COG1686	Belongs to the peptidase S11 family
EXW48_RS21125	COG1725	Transcriptional regulator
EXW48_RS21130	COG1131	(ABC) transporter
EXW48_RS21150	COG1846	Transcriptional regulator
EXW48_RS21165	COG0598	Magnesium transport protein CorA
EXW48_RS21190	COG4974	Belongs to the 'phage' integrase family
EXW48_RS21200	COG0735	belongs to the Fur family
EXW48_RS21205	COG1300	Membrane
EXW48_RS21225	COG0667	Aldo Keto reductase
EXW48_RS21230	COG0656	L-ascorbic acid biosynthetic process
EXW48_RS21235	COG0456	acetyltransferase
EXW48_RS21235	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW48_RS21245	COG0737	Belongs to the 5'-nucleotidase family
EXW48_RS21245	COG1525	nuclease
EXW48_RS21245	COG4085	toxin activity
EXW48_RS21255	COG0596	Alpha beta hydrolase
EXW48_RS21260	COG2056	Na+-H+ antiporter family
EXW48_RS21265	COG1609	Transcriptional regulator
EXW48_RS21270	COG0456	acetyltransferase
EXW48_RS21275	COG1073	alpha beta
EXW48_RS21290	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW48_RS21290	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW48_RS21295	COG0307	riboflavin synthase, alpha
EXW48_RS21320	COG4106	trans-aconitate 2-methyltransferase activity
EXW48_RS21325	COG2226	methyltransferase
EXW48_RS21325	COG1073	alpha beta
EXW48_RS21340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW48_RS21350	COG1757	Na H antiporter
EXW48_RS21355	COG0737	Belongs to the 5'-nucleotidase family
EXW48_RS21365	COG1522	sequence-specific DNA binding
EXW48_RS21390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW48_RS21410	COG0300	oxidoreductase activity
EXW48_RS21415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS21420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW48_RS21425	COG1760	l-serine dehydratase
EXW48_RS21430	COG1760	l-serine dehydratase
EXW48_RS21460	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW48_RS21465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS21480	COG1376	ErfK ybiS ycfS ynhG family protein
EXW48_RS21485	COG4129	membrane
EXW48_RS21490	COG1126	abc transporter atp-binding protein
EXW48_RS21495	COG0765	amino acid transport
EXW48_RS21500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW48_RS21520	COG2323	membrane
EXW48_RS21525	COG0772	Belongs to the SEDS family
EXW48_RS21530	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW48_RS21535	COG0022	dehydrogenase e1 component
EXW48_RS21540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW48_RS21545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW48_RS21560	COG0280	phosphate acetyltransferase
EXW48_RS21565	COG3829	transcription factor binding
EXW48_RS21565	COG3290	protein histidine kinase activity
EXW48_RS21575	COG0584	glycerophosphoryl diester phosphodiesterase
EXW48_RS21580	COG3093	addiction module antidote protein HigA
EXW48_RS21590	COG0745	RESPONSE REGULATOR receiver
EXW48_RS21595	COG0750	zinc metalloprotease
EXW48_RS21600	COG0497	DNA recombination
EXW48_RS21610	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW48_RS21620	COG0142	geranyltranstransferase activity
EXW48_RS21645	COG1302	Protein conserved in bacteria
EXW48_RS21650	COG0439	Biotin carboxylase
EXW48_RS21655	COG0511	ligase activity, forming carbon-carbon bonds
EXW48_RS21700	COG3854	ATPases associated with a variety of cellular activities
EXW48_RS21715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW48_RS21720	COG0006	proline dipeptidase activity
EXW48_RS21735	COG3872	metal-dependent enzyme
EXW48_RS21745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW48_RS21775	COG0095	Lipoate-protein ligase
EXW48_RS21780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS21790	COG1609	Transcriptional regulator
EXW48_RS21800	COG2076	Multidrug Resistance protein
EXW48_RS21805	COG2076	Multidrug Resistance protein
EXW48_RS21840	COG1131	(ABC) transporter
EXW48_RS21845	COG1725	Transcriptional regulator
EXW48_RS21860	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW48_RS21875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW48_RS22030	COG1410	methionine synthase
EXW48_RS22030	COG0646	methionine synthase
EXW48_RS22035	COG0646	methionine synthase
EXW48_RS22035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW48_RS22040	COG0626	cystathionine gamma-synthase activity
EXW48_RS22045	COG0626	cystathionine gamma-synthase activity
EXW48_RS22065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS22075	COG1940	carbohydrate kinase activity
EXW48_RS22080	COG4483	Protein conserved in bacteria
EXW48_RS22085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW48_RS22090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW48_RS22095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW48_RS22100	COG0704	Plays a role in the regulation of phosphate uptake
EXW48_RS22110	COG0581	inorganic phosphate transmembrane transporter activity
EXW48_RS22115	COG0573	inorganic phosphate transmembrane transporter activity
EXW48_RS22120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW48_RS22125	COG0768	penicillin binding
EXW48_RS22130	COG0477	Major facilitator Superfamily
EXW48_RS22135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW48_RS22160	COG0735	belongs to the Fur family
EXW48_RS22165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW48_RS22170	COG1121	(ABC) transporter
EXW48_RS22175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS22205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW48_RS22210	COG2384	SAM-dependent methyltransferase
EXW48_RS22215	COG2010	Cytochrome c
EXW48_RS22220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW48_RS22225	COG0358	DNA primase activity
EXW48_RS22235	COG0517	IMP dehydrogenase activity
EXW48_RS22250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW48_RS22255	COG0295	cytidine deaminase activity
EXW48_RS22260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW48_RS22270	COG1480	7TM receptor with intracellular HD hydrolase
EXW48_RS22275	COG1702	phosphate starvation-inducible protein PhoH
EXW48_RS22290	COG1610	YqeY-like protein
EXW48_RS22295	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW48_RS22300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW48_RS22305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW48_RS22335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW48_RS22340	COG1733	regulation of RNA biosynthetic process
EXW48_RS22365	COG1466	dna polymerase III delta subunit
EXW48_RS22375	COG2333	competence protein COMEC
EXW48_RS22375	COG0658	competence protein
EXW48_RS22380	COG2131	deaminase
EXW48_RS22385	COG1555	photosystem II stabilization
EXW48_RS22385	COG1596	polysaccharide export
EXW48_RS22390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW48_RS22395	COG2226	methyltransferase
EXW48_RS22400	COG0799	negative regulation of ribosome biogenesis
EXW48_RS22405	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW48_RS22415	COG1534	Rna-binding protein
EXW48_RS22425	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW48_RS22430	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW48_RS22455	COG1595	DNA-templated transcription, initiation
EXW48_RS22465	COG0778	Nitroreductase
EXW48_RS22470	COG2357	RelA SpoT domain protein
EXW48_RS22480	COG1785	Belongs to the alkaline phosphatase family
EXW48_RS22490	COG2267	carboxylic ester hydrolase activity
EXW48_RS22525	COG1404	Belongs to the peptidase S8 family
EXW48_RS22530	COG3186	Phenylalanine-4-hydroxylase
EXW48_RS22540	COG2514	catechol 2,3-dioxygenase activity
EXW48_RS22545	COG2259	Doxx family
EXW48_RS22585	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW48_RS22595	COG1454	alcohol dehydrogenase
EXW48_RS22595	COG1012	belongs to the aldehyde dehydrogenase family
EXW48_RS22600	COG0626	cystathionine gamma-synthase activity
EXW48_RS22605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW48_RS22630	COG0768	penicillin binding
EXW48_RS22645	COG0826	peptidase U32
EXW48_RS22650	COG0826	peptidase U32
EXW48_RS22655	COG4122	O-methyltransferase activity
EXW48_RS22660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW48_RS22670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW48_RS22695	COG0628	permease
EXW48_RS22715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW48_RS22730	COG1104	cysteine desulfurase activity
EXW48_RS22735	COG1959	2 iron, 2 sulfur cluster binding
EXW48_RS22740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW48_RS22750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW48_RS22775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW48_RS22785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW48_RS22785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW48_RS22790	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW48_RS22795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW48_RS22795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW48_RS22805	COG2244	polysaccharide biosynthetic process
EXW48_RS22810	COG2323	membrane
EXW48_RS22820	COG1862	Preprotein translocase
EXW48_RS22850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW48_RS22860	COG0697	spore germination
EXW48_RS22865	COG0640	Transcriptional regulator
EXW48_RS22890	COG0157	Belongs to the NadC ModD family
EXW48_RS22895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW48_RS22900	COG1104	cysteine desulfurase activity
EXW48_RS22905	COG1827	regulation of RNA biosynthetic process
EXW48_RS22910	COG2258	MOSC domain
EXW48_RS22915	COG0077	Prephenate dehydratase
EXW48_RS22920	COG0577	efflux transmembrane transporter activity
EXW48_RS22925	COG0577	efflux transmembrane transporter activity
EXW48_RS22930	COG1136	(ABC) transporter
EXW48_RS22935	COG5002	protein histidine kinase activity
EXW48_RS22940	COG0745	RESPONSE REGULATOR receiver
EXW48_RS22945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW48_RS22950	COG3290	protein histidine kinase activity
EXW48_RS22960	COG2868	ribosomal protein
EXW48_RS22970	COG1530	ribonuclease E activity
EXW48_RS22975	COG1994	Peptidase M50
EXW48_RS22980	COG0739	heme binding
EXW48_RS22985	COG2894	cell division
EXW48_RS23005	COG1077	Cell shape determining protein MreB Mrl
EXW48_RS23025	COG0285	dihydrofolate synthase activity
EXW48_RS23030	COG0525	valine-tRNA ligase activity
EXW48_RS23040	COG1388	LysM domain
EXW48_RS23050	COG0113	porphobilinogen synthase activity
EXW48_RS23075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW48_RS23085	COG1846	Transcriptional regulator
EXW48_RS23090	COG1764	response to oxidative stress
EXW48_RS23105	COG0470	DNA polymerase III
EXW48_RS23105	COG1067	ATP-dependent peptidase activity
EXW48_RS23155	COG0622	Phosphoesterase
EXW48_RS23170	COG5401	PFAM Sporulation and spore germination
EXW48_RS23190	COG2197	response regulator
EXW48_RS23195	COG2233	PERMEase
EXW48_RS23200	COG0402	S-adenosylhomocysteine deaminase activity
EXW48_RS23205	COG1983	PspC domain protein
EXW48_RS23215	COG1396	sequence-specific DNA binding
EXW48_RS23220	COG0697	spore germination
EXW48_RS23230	COG1959	2 iron, 2 sulfur cluster binding
EXW48_RS23235	COG1668	transmembrane transport
EXW48_RS23240	COG4152	abc transporter atp-binding protein
EXW48_RS23245	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW48_RS23250	COG1360	Flagellar Motor Protein
EXW48_RS23255	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW48_RS23260	COG1876	peptidase activity
EXW48_RS23265	COG0824	Thioesterase
EXW48_RS23270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW48_RS23275	COG1053	succinate dehydrogenase
EXW48_RS23280	COG2009	succinate dehydrogenase
EXW48_RS23285	COG1719	4-vinyl reductase, 4VR
EXW48_RS23295	COG3118	belongs to the thioredoxin family
EXW48_RS23300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW48_RS23305	COG2086	electron transfer activity
EXW48_RS23310	COG1024	Enoyl-CoA hydratase
EXW48_RS23315	COG1309	transcriptional regulator
EXW48_RS23320	COG0318	PFAM AMP-dependent synthetase and ligase
EXW48_RS23330	COG2318	DinB family
EXW48_RS23360	COG1131	(ABC) transporter
EXW48_RS23365	COG2205	protein histidine kinase activity
EXW48_RS23370	COG0745	RESPONSE REGULATOR receiver
EXW48_RS23380	COG4895	conserved protein (DUF2196)
EXW48_RS23385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW48_RS23395	COG4509	Sortase family
EXW48_RS23400	COG1120	ATPase activity
EXW48_RS23415	COG5386	Cell surface protein
EXW48_RS23420	COG5386	Cell surface protein
EXW48_RS23425	COG1114	Component of the transport system for branched-chain amino acids
EXW48_RS23430	COG1187	pseudouridine synthase activity
EXW48_RS23440	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW48_RS23440	COG1796	DNA polymerase
EXW48_RS23445	COG1286	toxin biosynthetic process
EXW48_RS23470	COG0443	Heat shock 70 kDa protein
EXW48_RS23480	COG0464	growth
EXW48_RS23515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW48_RS23525	COG1418	mRNA catabolic process
EXW48_RS23555	COG2814	Major facilitator Superfamily
EXW48_RS23560	COG1566	PFAM secretion protein HlyD family protein
EXW48_RS23565	COG1309	transcriptional regulator
EXW48_RS23570	COG1363	Peptidase, m42
EXW48_RS23580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW48_RS23595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW48_RS23605	COG1484	DNA-dependent DNA replication
EXW48_RS23610	COG3611	Membrane attachment protein
EXW48_RS23620	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW48_RS23625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW48_RS23630	COG0237	dephospho-CoA kinase activity
EXW48_RS23635	COG1971	Probably functions as a manganese efflux pump
EXW48_RS23645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW48_RS23645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW48_RS23650	COG5002	protein histidine kinase activity
EXW48_RS23655	COG0745	RESPONSE REGULATOR receiver
EXW48_RS23675	COG0538	isocitrate dehydrogenase activity
EXW48_RS23680	COG0372	Belongs to the citrate synthase family
EXW48_RS23690	COG0628	permease
EXW48_RS23695	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW48_RS23720	COG1725	Transcriptional regulator
EXW48_RS23725	COG0281	malic enzyme
EXW48_RS23730	COG0587	DNA-directed DNA polymerase activity
EXW48_RS23745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW48_RS23760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW48_RS23770	COG4109	DRTGG domain
EXW48_RS23785	COG0006	proline dipeptidase activity
EXW48_RS23825	COG0662	Cupin 2, conserved barrel domain protein
EXW48_RS23835	COG1476	TRANSCRIPTIONal
EXW48_RS23850	COG1028	Short-chain dehydrogenase reductase Sdr
EXW48_RS23855	COG0589	response to stress
EXW48_RS23890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS23915	COG0827	DNA restriction-modification system
EXW48_RS23920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW48_RS23925	COG3874	Sporulation protein YtfJ
EXW48_RS23940	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW48_RS23950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW48_RS23965	COG1104	cysteine desulfurase activity
EXW48_RS23975	COG0583	DNA-binding transcription factor activity
EXW48_RS23980	COG0697	spore germination
EXW48_RS23985	COG1309	transcriptional regulator
EXW48_RS23990	COG1956	GAF domain-containing protein
EXW48_RS24000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW48_RS24060	COG1595	DNA-templated transcription, initiation
EXW48_RS24070	COG0110	maltose O-acetyltransferase activity
EXW48_RS24075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW48_RS24080	COG0454	-acetyltransferase
EXW48_RS24085	COG0517	IMP dehydrogenase activity
EXW48_RS24090	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW48_RS24125	COG0745	RESPONSE REGULATOR receiver
EXW48_RS24130	COG5002	protein histidine kinase activity
EXW48_RS24135	COG0666	response to abiotic stimulus
EXW48_RS24170	COG1609	Transcriptional regulator
EXW48_RS24175	COG1605	Chorismate mutase
EXW48_RS24175	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW48_RS24180	COG4851	CamS sex pheromone cAM373 precursor
EXW48_RS24185	COG3118	belongs to the thioredoxin family
EXW48_RS24195	COG2309	aminopeptidase activity
EXW48_RS24220	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS24225	COG1695	Transcriptional regulator
EXW48_RS24240	COG1674	ftsk spoiiie
EXW48_RS24255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW48_RS24265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW48_RS24270	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW48_RS24275	COG1363	Peptidase, m42
EXW48_RS24285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS24300	COG0510	thiamine kinase activity
EXW48_RS24305	COG1523	belongs to the glycosyl hydrolase 13 family
EXW48_RS24315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW48_RS24320	COG1349	DNA-binding transcription factor activity
EXW48_RS24325	COG1187	pseudouridine synthase activity
EXW48_RS24330	COG2244	polysaccharide biosynthetic process
EXW48_RS24335	COG2081	HI0933 family
EXW48_RS24340	COG2814	Major facilitator Superfamily
EXW48_RS24350	COG3832	glyoxalase III activity
EXW48_RS24370	COG1329	Transcriptional regulator
EXW48_RS24395	COG0314	molybdopterin synthase activity
EXW48_RS24400	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW48_RS24405	COG0303	'Molybdopterin
EXW48_RS24415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW48_RS24420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW48_RS24440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW48_RS24450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW48_RS24495	COG2814	Major facilitator Superfamily
EXW48_RS24500	COG0475	glutathione-regulated potassium exporter activity
EXW48_RS24505	COG0490	domain, Protein
EXW48_RS24510	COG0582	viral genome integration into host DNA
EXW48_RS24520	COG1136	(ABC) transporter
EXW48_RS24540	COG1242	4 iron, 4 sulfur cluster binding
EXW48_RS24545	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW48_RS24550	COG1131	(ABC) transporter
EXW48_RS24560	COG1794	racemase activity, acting on amino acids and derivatives
EXW48_RS24590	COG2267	carboxylic ester hydrolase activity
EXW48_RS24595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW48_RS24600	COG0671	phosphoesterase, PA-phosphatase related
EXW48_RS24605	COG0438	transferase activity, transferring glycosyl groups
EXW48_RS24615	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW48_RS24670	COG5002	protein histidine kinase activity
EXW48_RS24675	COG4191	Histidine kinase
EXW48_RS24695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW48_RS24700	COG1116	anion transmembrane transporter activity
EXW48_RS24705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW48_RS24730	COG0494	nUDIX hydrolase
EXW48_RS24770	COG1854	S-ribosylhomocysteine lyase activity
EXW48_RS24780	COG0288	reversible hydration of carbon dioxide
EXW48_RS24785	COG1271	oxidase subunit
EXW48_RS24790	COG1294	oxidase, subunit
EXW48_RS24815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS24840	COG1842	Phage shock protein A
EXW48_RS24865	COG3859	Proton-coupled thiamine transporter YuaJ
EXW48_RS24870	COG5002	protein histidine kinase activity
EXW48_RS24875	COG0745	RESPONSE REGULATOR receiver
EXW48_RS24900	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW48_RS24905	COG1597	lipid kinase activity
EXW48_RS24940	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS24945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW48_RS24950	COG0577	efflux transmembrane transporter activity
EXW48_RS24955	COG1136	(ABC) transporter
EXW48_RS24960	COG3708	Transcriptional regulator
EXW48_RS24960	COG2207	Transcriptional regulator
EXW48_RS24965	COG0745	RESPONSE REGULATOR receiver
EXW48_RS24970	COG2205	protein histidine kinase activity
EXW48_RS24975	COG0577	efflux transmembrane transporter activity
EXW48_RS24980	COG0577	efflux transmembrane transporter activity
EXW48_RS24985	COG1136	(ABC) transporter
EXW48_RS24990	COG0577	efflux transmembrane transporter activity
EXW48_RS25005	COG2188	Transcriptional regulator
EXW48_RS25025	COG3964	amidohydrolase
EXW48_RS25045	COG4948	Mandelate Racemase Muconate Lactonizing
EXW48_RS25055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW48_RS25060	COG0596	Alpha beta hydrolase
EXW48_RS25070	COG1169	isochorismate synthase
EXW48_RS25075	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW48_RS25080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW48_RS25085	COG1278	Cold shock
EXW48_RS25100	COG0058	SHG alpha-glucan phosphorylase activity
EXW48_RS25110	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW48_RS25120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW48_RS25135	COG1396	sequence-specific DNA binding
EXW48_RS25285	COG1285	pathogenesis
EXW48_RS25290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW48_RS25305	COG2155	Conserved Protein
EXW48_RS25310	COG1098	S1 RNA binding domain
EXW48_RS25315	COG0436	Aminotransferase
EXW48_RS25320	COG1522	sequence-specific DNA binding
EXW48_RS25325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW48_RS25330	COG2267	carboxylic ester hydrolase activity
EXW48_RS25340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW48_RS25360	COG5018	Exonuclease
EXW48_RS25365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW48_RS25385	COG2050	protein possibly involved in aromatic compounds catabolism
EXW48_RS25395	COG1268	BioY protein
EXW48_RS25405	COG0297	glycogen (starch) synthase activity
EXW48_RS25425	COG4485	Bacterial membrane protein, YfhO
EXW48_RS25430	COG2246	polysaccharide biosynthetic process
EXW48_RS25435	COG0463	Glycosyl transferase, family 2
EXW48_RS25440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW48_RS25445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW48_RS25465	COG3584	3D domain protein
EXW48_RS25480	COG1252	NADH dehydrogenase
EXW48_RS25490	COG3708	Transcriptional regulator
EXW48_RS25505	COG1683	Conserved Protein
EXW48_RS25530	COG0316	Belongs to the HesB IscA family
EXW48_RS25545	COG1252	NADH dehydrogenase
EXW48_RS25560	COG0390	transport system, permease component
EXW48_RS25570	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW48_RS25590	COG4837	Protein of unknown function (DUF1462)
EXW48_RS25595	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW48_RS25605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW48_RS25610	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW48_RS25625	COG0577	efflux transmembrane transporter activity
EXW48_RS25625	COG1136	(ABC) transporter
EXW48_RS25630	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW48_RS25645	COG0647	UMP catabolic process
EXW48_RS25655	COG2445	Protein of unknown function DUF86
EXW48_RS25660	COG1494	fructose-1,6-bisphosphatase
EXW48_RS25675	COG4470	Protein conserved in bacteria
EXW48_RS25685	COG0789	Transcriptional regulator
EXW48_RS25690	COG4377	Putative membrane peptidase family (DUF2324)
EXW48_RS25715	COG0739	heme binding
EXW48_RS25725	COG3377	Domain of unknown function (DUF1805)
EXW48_RS25730	COG0737	Belongs to the 5'-nucleotidase family
EXW48_RS25735	COG0719	Fe-S assembly protein
EXW48_RS25740	COG0822	iron-sulfur transferase activity
EXW48_RS25745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW48_RS25750	COG0719	Fe-S assembly protein
EXW48_RS25755	COG0396	ATPase activity
EXW48_RS25760	COG1464	Belongs to the NlpA lipoprotein family
EXW48_RS25765	COG1464	Belongs to the NlpA lipoprotein family
EXW48_RS25770	COG2011	ABC-type metal ion transport system permease component
EXW48_RS25785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW48_RS25790	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW48_RS25800	COG1393	Belongs to the ArsC family
EXW48_RS25840	COG1309	transcriptional regulator
EXW48_RS25845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW48_RS25850	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS25855	COG0183	Belongs to the thiolase family
EXW48_RS25860	COG1024	Enoyl-CoA hydratase
EXW48_RS25860	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW48_RS25870	COG1686	Belongs to the peptidase S11 family
EXW48_RS25885	COG0011	TIGRFAM Protein of
EXW48_RS25890	COG0840	transmembrane signaling receptor activity
EXW48_RS25910	COG2814	Major facilitator Superfamily
EXW48_RS25915	COG0531	amino acid
EXW48_RS25935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW48_RS25950	COG5002	protein histidine kinase activity
EXW48_RS25955	COG0745	RESPONSE REGULATOR receiver
EXW48_RS25960	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW48_RS25970	COG1131	(ABC) transporter
EXW48_RS25995	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS26005	COG1376	ErfK ybiS ycfS ynhG family protein
EXW48_RS26010	COG0745	RESPONSE REGULATOR receiver
EXW48_RS26015	COG5002	protein histidine kinase activity
EXW48_RS26045	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW48_RS26050	COG3227	Zinc metalloprotease (Elastase)
EXW48_RS26055	COG1741	Belongs to the pirin family
EXW48_RS26070	COG0586	Pfam SNARE associated Golgi protein
EXW48_RS26075	COG0475	glutathione-regulated potassium exporter activity
EXW48_RS26080	COG0490	domain, Protein
EXW48_RS26085	COG1115	amino acid carrier protein
EXW48_RS26095	COG0783	Belongs to the Dps family
EXW48_RS26110	COG1611	Belongs to the LOG family
EXW48_RS26130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS26135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS26140	COG1115	amino acid carrier protein
EXW48_RS26145	COG1115	amino acid carrier protein
EXW48_RS26150	COG2910	NAD(P)H-binding
EXW48_RS26165	COG0656	L-ascorbic acid biosynthetic process
EXW48_RS26170	COG2814	Major facilitator Superfamily
EXW48_RS26175	COG1733	regulation of RNA biosynthetic process
EXW48_RS26185	COG1252	NADH dehydrogenase
EXW48_RS26190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EXW48_RS26205	COG0840	transmembrane signaling receptor activity
EXW48_RS26205	COG3290	protein histidine kinase activity
EXW48_RS26220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW48_RS26240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW48_RS26260	COG1522	sequence-specific DNA binding
EXW48_RS26265	COG0288	reversible hydration of carbon dioxide
EXW48_RS26270	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW48_RS26275	COG2233	PERMEase
EXW48_RS26335	COG5658	integral membrane protein
EXW48_RS26340	COG0640	Transcriptional regulator
EXW48_RS26375	COG0419	ATPase involved in DNA repair
EXW48_RS26390	COG0557	exoribonuclease II activity
EXW48_RS26395	COG1647	Serine aminopeptidase, S33
EXW48_RS26400	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW48_RS26405	COG1346	cytolysis
EXW48_RS26420	COG0148	phosphopyruvate hydratase activity
EXW48_RS26440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW48_RS26455	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW48_RS26535	COG5294	Protein conserved in bacteria
EXW48_RS26555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW48_RS26570	COG2323	membrane
EXW48_RS26580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW48_RS26590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW48_RS26600	COG1051	belongs to the nudix hydrolase family
EXW48_RS26610	COG0492	ferredoxin-NADP+ reductase activity
EXW48_RS26615	COG0457	Tetratricopeptide repeat
EXW48_RS26620	COG0110	maltose O-acetyltransferase activity
EXW48_RS26640	COG1950	PFAM Membrane protein of
EXW48_RS26650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW48_RS26655	COG0556	nucleotide-excision repair
EXW48_RS26670	COG0789	Transcriptional regulator
EXW48_RS26705	COG0583	DNA-binding transcription factor activity
EXW48_RS26715	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW48_RS26730	COG1132	(ABC) transporter
EXW48_RS26735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW48_RS26740	COG0793	Belongs to the peptidase S41A family
EXW48_RS26740	COG3409	Peptidoglycan-binding domain 1 protein
EXW48_RS26745	COG2177	Part of the ABC transporter FtsEX involved in
EXW48_RS26750	COG2884	Cell division ATP-binding protein ftsE
EXW48_RS26770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXW48_RS26775	COG1278	Cold shock
EXW48_RS26780	COG1040	competence protein
EXW48_RS26785	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW48_RS26795	COG1733	regulation of RNA biosynthetic process
EXW48_RS26800	COG1307	EDD domain protein, DegV family
EXW48_RS26805	COG1739	Uncharacterized protein family UPF0029
EXW48_RS26810	COG1316	TRANSCRIPTIONal
EXW48_RS26815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW48_RS26820	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW48_RS26825	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW48_RS26835	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW48_RS26835	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW48_RS26855	COG1486	melibiose metabolic process
EXW48_RS26860	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW48_RS26865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW48_RS26875	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW48_RS26885	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW48_RS26895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW48_RS26900	COG1301	dicarboxylic acid transport
EXW48_RS26910	COG0346	lactoylglutathione lyase activity
EXW48_RS26915	COG1511	domain protein
EXW48_RS26920	COG0583	DNA-binding transcription factor activity
EXW48_RS26925	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW48_RS26935	COG1271	oxidase subunit
EXW48_RS26940	COG1294	oxidase, subunit
EXW48_RS26945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW48_RS26955	COG1620	l-lactate permease
EXW48_RS26965	COG2389	metal-binding protein
EXW48_RS26975	COG1368	sulfuric ester hydrolase activity
EXW48_RS26990	COG0791	NLP P60 protein
EXW48_RS26990	COG1388	LysM domain
EXW48_RS26995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW48_RS27005	COG1215	transferase activity, transferring glycosyl groups
EXW48_RS27010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW48_RS27015	COG3584	3D domain protein
EXW48_RS27015	COG1388	LysM domain
EXW48_RS27025	COG4715	Zinc finger, swim domain protein
EXW48_RS27030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW48_RS27070	COG0577	efflux transmembrane transporter activity
EXW48_RS27075	COG1136	(ABC) transporter
EXW48_RS27095	COG2271	Major facilitator Superfamily
EXW48_RS27110	COG5002	protein histidine kinase activity
EXW48_RS27115	COG0745	RESPONSE REGULATOR receiver
EXW48_RS27120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW48_RS27140	COG1442	glycosyl transferase family 8
EXW48_RS27140	COG1216	Glycosyl transferase, family 2
EXW48_RS27150	COG0438	transferase activity, transferring glycosyl groups
EXW48_RS27155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW48_RS27165	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW48_RS27170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW48_RS27175	COG1086	Polysaccharide biosynthesis protein
EXW48_RS27180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW48_RS27185	COG4464	protein tyrosine phosphatase activity
EXW48_RS27190	COG0489	protein tyrosine kinase activity
EXW48_RS27195	COG3944	biosynthesis protein
EXW48_RS27200	COG0489	protein tyrosine kinase activity
EXW48_RS27215	COG1609	Transcriptional regulator
EXW48_RS27225	COG0739	heme binding
EXW48_RS27240	COG3279	Response regulator of the LytR AlgR family
EXW48_RS27255	COG2385	sporulation resulting in formation of a cellular spore
EXW48_RS27270	COG4836	Membrane
EXW48_RS27275	COG1007	ATP synthesis coupled electron transport
EXW48_RS27280	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW48_RS27285	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW48_RS27295	COG0839	Belongs to the complex I subunit 6 family
EXW48_RS27315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW48_RS27325	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW48_RS27330	COG3300	MHYT domain
EXW48_RS27330	COG5001	Diguanylate cyclase
EXW48_RS27350	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW48_RS27370	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW48_RS27380	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW48_RS27415	COG0698	ribose 5-phosphate isomerase
EXW48_RS27430	COG2259	Doxx family
EXW48_RS27435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW48_RS27450	COG0009	L-threonylcarbamoyladenylate synthase
EXW48_RS27465	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW48_RS27470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW48_RS27475	COG1435	thymidine kinase activity
EXW48_RS27485	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW48_RS27490	COG1494	fructose-1,6-bisphosphatase
EXW48_RS27510	COG4821	SIS domain
EXW48_RS27515	COG0504	CTP synthase activity
EXW48_RS27530	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS27535	COG1960	acyl-CoA dehydrogenase activity
EXW48_RS27540	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW48_RS27550	COG2181	nitrate reductase activity
EXW48_RS27550	COG0247	lactate metabolic process
EXW48_RS27555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW48_RS27565	COG3300	MHYT domain
EXW48_RS27565	COG5001	Diguanylate cyclase
EXW48_RS27585	COG2197	response regulator
EXW48_RS27590	COG4585	Histidine kinase
EXW48_RS27595	COG0842	Transport permease protein
EXW48_RS27600	COG1131	(ABC) transporter
EXW48_RS27605	COG0024	Methionine aminopeptidase
EXW48_RS27610	COG2234	aminopeptidase activity
EXW48_RS27635	COG1595	DNA-templated transcription, initiation
EXW48_RS27645	COG4506	Protein conserved in bacteria
EXW48_RS27650	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW48_RS27675	COG2814	Major facilitator Superfamily
EXW48_RS27680	COG0789	Transcriptional regulator
EXW48_RS27685	COG0584	glycerophosphoryl diester phosphodiesterase
EXW48_RS27690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW48_RS27700	COG1994	Peptidase M50
EXW48_RS27710	COG1078	dGTPase activity
EXW48_RS27715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW48_RS27720	COG1120	ATPase activity
EXW48_RS27725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS27730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW48_RS27735	COG4844	belongs to the
EXW48_RS27750	COG0280	phosphate acetyltransferase
EXW48_RS27765	COG3773	Cell wall hydrolase
EXW48_RS27775	COG2363	Small membrane protein
EXW48_RS27785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW48_RS27790	COG2233	PERMEase
EXW48_RS27795	COG0561	phosphatase activity
EXW48_RS27800	COG2814	Major facilitator Superfamily
EXW48_RS27810	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW48_RS27815	COG1131	(ABC) transporter
EXW48_RS27820	COG2755	lipolytic protein G-D-S-L family
EXW48_RS27825	COG1609	Transcriptional regulator
EXW48_RS27835	COG0460	homoserine dehydrogenase
EXW48_RS27845	COG2873	o-acetylhomoserine
EXW48_RS27865	COG1011	Hydrolase
EXW48_RS27870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW48_RS27880	COG2197	response regulator
EXW48_RS27885	COG2203	Gaf domain
EXW48_RS27885	COG4585	Histidine kinase
EXW48_RS27890	COG0351	phosphomethylpyrimidine kinase
EXW48_RS27895	COG3706	GGDEF domain
EXW48_RS27900	COG2879	small protein
EXW48_RS27905	COG1966	Carbon starvation protein
EXW48_RS27910	COG3279	Response regulator of the LytR AlgR family
EXW48_RS27915	COG0477	Major facilitator Superfamily
EXW48_RS27925	COG0438	transferase activity, transferring glycosyl groups
EXW48_RS27940	COG0840	transmembrane signaling receptor activity
EXW48_RS27950	COG1607	acyl-coa hydrolase
EXW48_RS27965	COG0488	(ABC) transporter
EXW48_RS27975	COG1309	transcriptional regulator
EXW48_RS27980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW48_RS27985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW48_RS27985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW48_RS27990	COG0628	permease
EXW48_RS28000	COG1380	Effector of murein hydrolase LrgA
EXW48_RS28005	COG3279	Response regulator of the LytR AlgR family
EXW48_RS28010	COG3275	phosphorelay sensor kinase activity
EXW48_RS28015	COG2814	Major facilitator Superfamily
EXW48_RS28020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW48_RS28025	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW48_RS28030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW48_RS28045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW48_RS28050	COG1272	protein, Hemolysin III
EXW48_RS28070	COG1164	Oligoendopeptidase f
EXW48_RS28090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW48_RS28095	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW48_RS28100	COG4853	Protein conserved in bacteria
EXW48_RS28105	COG4863	YycH protein
EXW48_RS28110	COG5002	protein histidine kinase activity
EXW48_RS28115	COG0745	RESPONSE REGULATOR receiver
EXW48_RS28145	COG0305	Participates in initiation and elongation during chromosome replication
EXW48_RS28155	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW48_RS28160	COG4241	membrane
EXW48_RS28170	COG0629	single-stranded DNA binding
EXW48_RS28180	COG0012	GTP binding
EXW48_RS28185	COG4481	Protein conserved in bacteria
EXW48_RS28190	COG0668	transmembrane transport
EXW48_RS28200	COG1475	DNA binding
EXW48_RS28205	COG1192	Involved in chromosome partitioning
EXW48_RS28230	COG1847	R3H domain protein
EXW48_RS28235	COG0706	membrane insertase activity
EXW48_RS28245	COG0230	Belongs to the bacterial ribosomal protein bL34 family