locus-tag	class	description
FHG85_RS00020	COG0756	dUTP diphosphatase activity
FHG85_RS00035	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FHG85_RS00045	COG2255	four-way junction helicase activity
FHG85_RS00050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FHG85_RS00060	COG0006	proline dipeptidase activity
FHG85_RS00075	COG1131	(ABC) transporter
FHG85_RS00095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FHG85_RS00100	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_RS00150	COG0616	signal peptide processing
FHG85_RS00155	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FHG85_RS00160	COG3040	lipid binding
FHG85_RS00165	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FHG85_RS00170	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FHG85_RS00175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FHG85_RS00180	COG1993	acr, cog1993
FHG85_RS00185	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHG85_RS00190	COG0740	serine-type endopeptidase activity
FHG85_RS00205	COG1940	carbohydrate kinase activity
FHG85_RS00210	COG1760	l-serine dehydratase
FHG85_RS00215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_RS00230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHG85_RS00240	COG0297	glycogen (starch) synthase activity
FHG85_RS00250	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FHG85_RS00260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHG85_RS00265	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FHG85_RS00275	COG1121	(ABC) transporter
FHG85_RS00280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHG85_RS00295	COG1595	DNA-templated transcription, initiation
FHG85_RS00315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHG85_RS00325	COG0358	DNA primase activity
FHG85_RS00335	COG0842	Transport permease protein
FHG85_RS00335	COG1716	ATPase activity
FHG85_RS00335	COG1131	(ABC) transporter
FHG85_RS00345	COG2204	response regulator
FHG85_RS00360	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_RS00365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHG85_RS00370	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FHG85_RS00380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FHG85_RS00400	COG2252	PERMEase
FHG85_RS00455	COG0367	asparagine synthase
FHG85_RS00465	COG0297	glycogen (starch) synthase activity
FHG85_RS00475	COG0688	phosphatidylethanolamine metabolic process
FHG85_RS00490	COG0124	histidyl-tRNA synthetase
FHG85_RS00495	COG2986	histidine ammonia-lyase
FHG85_RS00505	COG2003	Belongs to the UPF0758 family
FHG85_RS00510	COG1086	Polysaccharide biosynthesis protein
FHG85_RS00515	COG3787	Belongs to the UPF0306 family
FHG85_RS00520	COG3757	hydrolase, family 25
FHG85_RS00525	COG3852	Histidine kinase
FHG85_RS00530	COG0569	domain protein
FHG85_RS00535	COG2333	competence protein COMEC
FHG85_RS00535	COG0658	competence protein
FHG85_RS00545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHG85_RS00590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_RS00620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FHG85_RS00635	COG0268	Binds directly to 16S ribosomal RNA
FHG85_RS00645	COG0784	Response regulator, receiver
FHG85_RS00645	COG2205	protein histidine kinase activity
FHG85_RS00650	COG3876	Protein conserved in bacteria
FHG85_RS00655	COG0328	RNA-DNA hybrid ribonuclease activity
FHG85_RS00655	COG3341	Caulimovirus viroplasmin
FHG85_RS00665	COG1663	tetraacyldisaccharide 4'-kinase activity
FHG85_RS00670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FHG85_RS00675	COG1040	competence protein
FHG85_RS00695	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FHG85_RS00695	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FHG85_RS00700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FHG85_RS00710	COG4172	Belongs to the ABC transporter superfamily
FHG85_RS00715	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FHG85_RS00735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FHG85_RS00755	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FHG85_RS00755	COG0662	Cupin 2, conserved barrel domain protein
FHG85_RS00760	COG0306	phosphate transporter
FHG85_RS00765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FHG85_RS00780	COG1027	Aspartate ammonia-lyase
FHG85_RS00815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHG85_RS00830	COG1774	PSP1 C-terminal conserved region
FHG85_RS00835	COG0470	DNA polymerase III
FHG85_RS00840	COG0126	phosphoglycerate kinase activity
FHG85_RS00845	COG1342	Belongs to the UPF0251 family
FHG85_RS00860	COG0730	response to heat
FHG85_RS00865	COG1473	amidohydrolase
FHG85_RS00875	COG2920	part of a sulfur-relay system
FHG85_RS00880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FHG85_RS00890	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHG85_RS00895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FHG85_RS00900	COG0557	exoribonuclease II activity
FHG85_RS00930	COG2274	protein secretion by the type I secretion system
FHG85_RS00965	COG0180	Tryptophanyl-tRNA synthetase
FHG85_RS00985	COG0017	Asparaginyl-tRNA synthetase
FHG85_RS00990	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FHG85_RS01000	COG0163	prenyltransferase activity
FHG85_RS01015	COG0321	lipoyl(octanoyl) transferase activity
FHG85_RS01020	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FHG85_RS01020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FHG85_RS01025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHG85_RS01030	COG0484	heat shock protein binding
FHG85_RS01035	COG0489	protein tyrosine kinase activity
FHG85_RS01040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FHG85_RS01045	COG0719	Fe-S assembly protein
FHG85_RS01055	COG0396	ATPase activity
FHG85_RS01060	COG0719	Fe-S assembly protein
FHG85_RS01070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHG85_RS01090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_RS01100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FHG85_RS01110	COG0606	chelatase, subunit chli
FHG85_RS01115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_RS01125	COG0495	leucyl-tRNA aminoacylation
FHG85_RS01135	COG0628	permease
FHG85_RS01150	COG1668	transmembrane transport
FHG85_RS01155	COG4152	abc transporter atp-binding protein
FHG85_RS01175	COG0802	atpase or kinase
FHG85_RS01180	COG0686	Belongs to the AlaDH PNT family
FHG85_RS01190	COG4942	peptidase
FHG85_RS01195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FHG85_RS01205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FHG85_RS01225	COG2315	Protein conserved in bacteria
FHG85_RS01230	COG0792	nuclease activity
FHG85_RS01240	COG1619	proteins homologs of microcin C7 resistance protein MccF
FHG85_RS01250	COG5002	protein histidine kinase activity
FHG85_RS01260	COG1473	amidohydrolase
FHG85_RS01265	COG0697	spore germination
FHG85_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_RS01280	COG0047	phosphoribosylformylglycinamidine synthase activity
FHG85_RS01290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_RS01300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_RS01330	COG0842	Transport permease protein
FHG85_RS01330	COG1131	(ABC) transporter
FHG85_RS01330	COG1716	ATPase activity
FHG85_RS01345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FHG85_RS01355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHG85_RS01360	COG2094	Belongs to the DNA glycosylase MPG family
FHG85_RS01375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FHG85_RS01395	COG0726	polysaccharide deacetylase
FHG85_RS01430	COG0233	cytoplasmic translational termination
FHG85_RS01435	COG0528	UMP kinase activity
FHG85_RS01450	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FHG85_RS01455	COG1349	DNA-binding transcription factor activity
FHG85_RS01460	COG0688	phosphatidylethanolamine metabolic process
FHG85_RS01465	COG4589	Belongs to the CDS family
FHG85_RS01475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHG85_RS01515	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FHG85_RS01520	COG1053	succinate dehydrogenase
FHG85_RS01530	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHG85_RS01535	COG1160	GTP binding
FHG85_RS01550	COG0572	uridine kinase
FHG85_RS01555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FHG85_RS01570	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FHG85_RS01575	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FHG85_RS01590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FHG85_RS01605	COG0596	Alpha beta hydrolase
FHG85_RS01615	COG0572	uridine kinase
FHG85_RS01620	COG1482	cell wall glycoprotein biosynthetic process
FHG85_RS01655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FHG85_RS01665	COG2205	protein histidine kinase activity
FHG85_RS01665	COG0784	Response regulator, receiver
FHG85_RS01670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FHG85_RS01680	COG0460	homoserine dehydrogenase
FHG85_RS01685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FHG85_RS01700	COG0154	amidase activity
FHG85_RS01705	COG0612	Peptidase, M16
FHG85_RS01710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHG85_RS01755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHG85_RS01760	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FHG85_RS01770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHG85_RS01780	COG1137	ATPase activity
FHG85_RS01795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FHG85_RS01800	COG0228	four-way junction DNA binding
FHG85_RS01815	COG3279	Response regulator of the LytR AlgR family
FHG85_RS01820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FHG85_RS01825	COG0242	peptide deformylase activity
FHG85_RS01835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FHG85_RS01840	COG0052	Belongs to the universal ribosomal protein uS2 family
FHG85_RS01845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FHG85_RS01895	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FHG85_RS01900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FHG85_RS01905	COG0632	four-way junction helicase activity
FHG85_RS01915	COG0509	glycine decarboxylation via glycine cleavage system
FHG85_RS01920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FHG85_RS01925	COG0739	heme binding
FHG85_RS01930	COG0084	hydrolase, TatD family'
FHG85_RS01935	COG0252	asparaginase activity
FHG85_RS01945	COG0811	peptide transport
FHG85_RS01965	COG1785	Belongs to the alkaline phosphatase family
FHG85_RS02005	COG0116	Belongs to the methyltransferase superfamily
FHG85_RS02005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FHG85_RS02010	COG0826	peptidase U32
FHG85_RS02015	COG0561	phosphatase activity
FHG85_RS02025	COG0590	tRNA wobble adenosine to inosine editing
FHG85_RS02030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FHG85_RS02040	COG4946	Tricorn protease homolog
FHG85_RS02040	COG1506	peptidase
FHG85_RS02040	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_RS02045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHG85_RS02050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FHG85_RS02070	COG4535	Mg2 and Co2 transporter CorC
FHG85_RS02075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_RS02090	COG2885	chlorophyll binding
FHG85_RS02095	COG2095	MarC family integral membrane protein
FHG85_RS02115	COG3958	Transketolase
FHG85_RS02120	COG3959	Transketolase, thiamine diphosphate binding domain
FHG85_RS02135	COG0217	transcriptional regulatory protein
FHG85_RS02140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_RS02155	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FHG85_RS02160	COG0527	aspartate kinase activity
FHG85_RS02165	COG0745	RESPONSE REGULATOR receiver
FHG85_RS02170	COG5002	protein histidine kinase activity
FHG85_RS02180	COG2885	chlorophyll binding
FHG85_RS02210	COG0463	Glycosyl transferase, family 2
FHG85_RS02240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FHG85_RS02250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHG85_RS02255	COG1045	serine acetyltransferase
FHG85_RS02260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHG85_RS02265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FHG85_RS02270	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FHG85_RS02280	COG4585	Histidine kinase
FHG85_RS02285	COG2197	response regulator
FHG85_RS02320	COG2205	protein histidine kinase activity
FHG85_RS02320	COG0784	Response regulator, receiver
FHG85_RS02330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FHG85_RS02360	COG1309	transcriptional regulator
FHG85_RS02400	COG1595	DNA-templated transcription, initiation
FHG85_RS02415	COG0612	Peptidase, M16
FHG85_RS02420	COG0604	alcohol dehydrogenase
FHG85_RS02430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHG85_RS02455	COG1519	Transferase
FHG85_RS02460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_RS02465	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FHG85_RS02465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FHG85_RS02470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_RS02475	COG1078	dGTPase activity
FHG85_RS02565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_RS02575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHG85_RS02605	COG0254	rRNA binding
FHG85_RS02615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FHG85_RS02620	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHG85_RS02630	COG1051	belongs to the nudix hydrolase family
FHG85_RS02635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FHG85_RS02660	COG0577	efflux transmembrane transporter activity
FHG85_RS02660	COG1136	(ABC) transporter
FHG85_RS02685	COG2001	Belongs to the MraZ family
FHG85_RS02690	COG0275	rRNA processing
FHG85_RS02700	COG0768	penicillin binding
FHG85_RS02710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHG85_RS02715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FHG85_RS02720	COG0772	Belongs to the SEDS family
FHG85_RS02725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FHG85_RS02730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FHG85_RS02760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FHG85_RS02785	COG1295	ribonuclease BN
FHG85_RS02790	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FHG85_RS02790	COG0778	Nitroreductase
FHG85_RS02795	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FHG85_RS02835	COG1902	pentaerythritol trinitrate reductase activity
FHG85_RS02835	COG0446	pyridine nucleotide-disulphide oxidoreductase
FHG85_RS02840	COG0166	Belongs to the GPI family
FHG85_RS02845	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHG85_RS02850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHG85_RS02875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHG85_RS02885	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FHG85_RS02885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHG85_RS02895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FHG85_RS02900	COG0598	Magnesium transport protein CorA
FHG85_RS02930	COG1388	LysM domain
FHG85_RS02930	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHG85_RS02935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FHG85_RS02950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHG85_RS02960	COG1335	isochorismatase
FHG85_RS02990	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FHG85_RS03010	COG0488	(ABC) transporter
FHG85_RS03030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FHG85_RS03035	COG0196	riboflavin kinase activity
FHG85_RS03050	COG0438	transferase activity, transferring glycosyl groups
FHG85_RS03065	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FHG85_RS03075	COG0138	bifunctional purine biosynthesis protein purh
FHG85_RS03095	COG0768	penicillin binding
FHG85_RS03100	COG0772	Belongs to the SEDS family
FHG85_RS03110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_RS03120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHG85_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHG85_RS03135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FHG85_RS03145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_RS03230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_RS03235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FHG85_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FHG85_RS03255	COG1136	(ABC) transporter
FHG85_RS03260	COG1136	(ABC) transporter
FHG85_RS03260	COG0577	efflux transmembrane transporter activity
FHG85_RS03270	COG3279	Response regulator of the LytR AlgR family
FHG85_RS03295	COG0492	ferredoxin-NADP+ reductase activity
FHG85_RS03300	COG1233	COG1233 Phytoene dehydrogenase and related
FHG85_RS03310	COG3104	oligopeptide transport
FHG85_RS03315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FHG85_RS03315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FHG85_RS03350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FHG85_RS03365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FHG85_RS03375	COG0305	Participates in initiation and elongation during chromosome replication
FHG85_RS03390	COG0724	RNA recognition motif
FHG85_RS03395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FHG85_RS03405	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS03405	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_RS03410	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS03435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FHG85_RS03450	COG0494	nUDIX hydrolase
FHG85_RS03455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHG85_RS03460	COG1678	Uncharacterized ACR, COG1678
FHG85_RS03470	COG0022	dehydrogenase e1 component
FHG85_RS03485	COG1477	protein flavinylation
FHG85_RS03505	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHG85_RS03510	COG0129	dihydroxy-acid dehydratase activity
FHG85_RS03515	COG0028	Belongs to the TPP enzyme family
FHG85_RS03520	COG0440	acetolactate synthase activity
FHG85_RS03525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FHG85_RS03530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FHG85_RS03535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FHG85_RS03540	COG0066	3-isopropylmalate dehydratase activity
FHG85_RS03545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FHG85_RS03550	COG0473	3-isopropylmalate dehydrogenase activity
FHG85_RS03560	COG0302	gtp cyclohydrolase
FHG85_RS03575	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FHG85_RS03590	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHG85_RS03605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHG85_RS03615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FHG85_RS03620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FHG85_RS03625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FHG85_RS03630	COG0204	Acyl-transferase
FHG85_RS03660	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_RS03665	COG3239	Fatty acid desaturase
FHG85_RS03700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FHG85_RS03720	COG0848	biopolymer transport protein
FHG85_RS03725	COG0811	peptide transport
FHG85_RS03735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FHG85_RS03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_RS03740	COG0784	Response regulator, receiver
FHG85_RS03740	COG2205	protein histidine kinase activity
FHG85_RS03740	COG2198	Histidine kinase
FHG85_RS03745	COG3022	response to hydroperoxide
FHG85_RS03755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHG85_RS03765	COG0038	chloride channel
FHG85_RS03770	COG0612	Peptidase, M16
FHG85_RS03785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHG85_RS03790	COG0735	belongs to the Fur family
FHG85_RS03795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FHG85_RS03825	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_RS03835	COG1136	(ABC) transporter
FHG85_RS03840	COG2096	Adenosyltransferase
FHG85_RS03855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_RS03865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHG85_RS03870	COG0516	GMP reductase activity
FHG85_RS03870	COG0517	IMP dehydrogenase activity
FHG85_RS03885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_RS03910	COG0668	transmembrane transport
FHG85_RS03915	COG0590	tRNA wobble adenosine to inosine editing
FHG85_RS03925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHG85_RS03930	COG0488	(ABC) transporter
FHG85_RS03950	COG2878	Part of a membrane complex involved in electron transport
FHG85_RS03950	COG1245	4Fe-4S binding domain
FHG85_RS03955	COG4656	Part of a membrane complex involved in electron transport
FHG85_RS03960	COG4658	electron transport chain
FHG85_RS03970	COG4660	Part of a membrane complex involved in electron transport
FHG85_RS03975	COG4657	Part of a membrane complex involved in electron transport
FHG85_RS03980	COG3291	Pkd domain containing protein
FHG85_RS03985	COG2186	Transcriptional regulator
FHG85_RS03990	COG4771	TonB-dependent receptor
FHG85_RS03995	COG0702	epimerase
FHG85_RS04025	COG2271	Major facilitator Superfamily
FHG85_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_RS04040	COG0800	Aldolase
FHG85_RS04045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHG85_RS04050	COG0739	heme binding
FHG85_RS04065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FHG85_RS04090	COG1704	LemA family
FHG85_RS04105	COG1518	maintenance of DNA repeat elements
FHG85_RS04110	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FHG85_RS04120	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FHG85_RS04140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FHG85_RS04160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FHG85_RS04165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHG85_RS04175	COG0390	transport system, permease component
FHG85_RS04180	COG0488	(ABC) transporter
FHG85_RS04185	COG3457	Alanine racemase
FHG85_RS04225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FHG85_RS04235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FHG85_RS04245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_RS04265	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_RS04270	COG1805	sodium ion transport
FHG85_RS04275	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_RS04285	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FHG85_RS04290	COG2871	sodium ion transport
FHG85_RS04310	COG4221	oxidoreductase activity
FHG85_RS04315	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHG85_RS04320	COG2226	methyltransferase
FHG85_RS04330	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FHG85_RS04335	COG1876	peptidase activity
FHG85_RS04345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHG85_RS04355	COG1830	Aldolase
FHG85_RS04360	COG0733	neurotransmitter:sodium symporter activity
FHG85_RS04365	COG1115	amino acid carrier protein
FHG85_RS04375	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FHG85_RS04380	COG4974	Belongs to the 'phage' integrase family
FHG85_RS04410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FHG85_RS04430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FHG85_RS04435	COG0081	regulation of translation
FHG85_RS04440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FHG85_RS04445	COG0222	ribosome binding
FHG85_RS04450	COG0085	RNA polymerase activity
FHG85_RS04480	COG0493	'glutamate synthase
FHG85_RS04480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_RS04515	COG1082	Xylose isomerase domain protein TIM barrel
FHG85_RS04520	COG1966	Carbon starvation protein
FHG85_RS04530	COG0602	queuosine metabolic process
FHG85_RS04535	COG2985	domain, Protein
FHG85_RS04540	COG0339	signal peptide processing
FHG85_RS04545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_RS04575	COG0492	ferredoxin-NADP+ reductase activity
FHG85_RS04580	COG0156	8-amino-7-oxononanoate synthase activity
FHG85_RS04605	COG0497	DNA recombination
FHG85_RS04610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FHG85_RS04615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHG85_RS04630	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FHG85_RS04660	COG0187	DNA topoisomerase II activity
FHG85_RS04675	COG1741	Belongs to the pirin family
FHG85_RS04680	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FHG85_RS04685	COG2217	Heavy metal translocating P-type atpase
FHG85_RS04690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FHG85_RS04700	COG2205	protein histidine kinase activity
FHG85_RS04710	COG1971	Probably functions as a manganese efflux pump
FHG85_RS04715	COG2885	chlorophyll binding
FHG85_RS04735	COG0746	molybdenum cofactor guanylyltransferase activity
FHG85_RS04740	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_RS04745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FHG85_RS04755	COG3279	Response regulator of the LytR AlgR family
FHG85_RS04760	COG0745	RESPONSE REGULATOR receiver
FHG85_RS04765	COG0556	nucleotide-excision repair
FHG85_RS04770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHG85_RS04790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHG85_RS04800	COG1288	antiporter activity
FHG85_RS04820	COG0025	NhaP-type Na H and K H
FHG85_RS04830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FHG85_RS04840	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS04845	COG0205	6-phosphofructokinase activity
FHG85_RS04860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHG85_RS04875	COG0542	response to heat
FHG85_RS04880	COG1074	ATP-dependent DNA helicase activity
FHG85_RS04885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_RS04890	COG1242	4 iron, 4 sulfur cluster binding
FHG85_RS04905	COG0840	transmembrane signaling receptor activity
FHG85_RS04910	COG3033	Beta-eliminating lyase
FHG85_RS04925	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FHG85_RS04935	COG2204	response regulator
FHG85_RS04950	COG0527	aspartate kinase activity
FHG85_RS04955	COG0019	diaminopimelate decarboxylase activity
FHG85_RS04960	COG0318	PFAM AMP-dependent synthetase and ligase
FHG85_RS04965	COG1216	Glycosyl transferase, family 2
FHG85_RS04975	COG0483	inositol monophosphate 1-phosphatase activity
FHG85_RS04985	COG0602	queuosine metabolic process
FHG85_RS04990	COG0737	Belongs to the 5'-nucleotidase family
FHG85_RS04995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHG85_RS05020	COG0840	transmembrane signaling receptor activity
FHG85_RS05025	COG0534	Mate efflux family protein
FHG85_RS05035	COG1368	sulfuric ester hydrolase activity
FHG85_RS05055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FHG85_RS05065	COG1320	monovalent cation:proton antiporter activity
FHG85_RS05090	COG2111	Na H antiporter
FHG85_RS05095	COG2111	Na H antiporter
FHG85_RS05095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FHG85_RS05100	COG4251	negative regulation of phosphorylation
FHG85_RS05110	COG1765	OsmC-like protein
FHG85_RS05125	COG3118	belongs to the thioredoxin family
FHG85_RS05140	COG1446	asparaginase
FHG85_RS05185	COG1120	ATPase activity
FHG85_RS05190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHG85_RS05240	COG1151	hydroxylamine reductase activity
FHG85_RS05255	COG3005	denitrification pathway
FHG85_RS05260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FHG85_RS05270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FHG85_RS05285	COG0336	Belongs to the RNA methyltransferase TrmD family
FHG85_RS05295	COG1331	Highly conserved protein containing a thioredoxin domain
FHG85_RS05305	COG0071	Belongs to the small heat shock protein (HSP20) family
FHG85_RS05315	COG0504	CTP synthase activity
FHG85_RS05320	COG0706	membrane insertase activity
FHG85_RS05325	COG1228	amidohydrolase
FHG85_RS05350	COG0442	prolyl-tRNA aminoacylation
FHG85_RS05375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHG85_RS05380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHG85_RS05385	COG0037	tRNA processing
FHG85_RS05390	COG0488	(ABC) transporter
FHG85_RS05415	COG1714	RDD family
FHG85_RS05425	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FHG85_RS05430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FHG85_RS05445	COG3591	Belongs to the peptidase S1B family
FHG85_RS05460	COG3279	Response regulator of the LytR AlgR family
FHG85_RS05470	COG2205	protein histidine kinase activity
FHG85_RS05470	COG0784	Response regulator, receiver
FHG85_RS05470	COG2198	Histidine kinase
FHG85_RS05470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_RS05505	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_RS05510	COG1218	3'(2'),5'-bisphosphate nucleotidase
FHG85_RS05520	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FHG85_RS05530	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHG85_RS05540	COG0251	oxidation-reduction process
FHG85_RS05545	COG0359	binds to the 23S rRNA
FHG85_RS05550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FHG85_RS05555	COG0360	Binds together with S18 to 16S ribosomal RNA
FHG85_RS05565	COG0813	purine-nucleoside phosphorylase activity
FHG85_RS05580	COG0612	Peptidase, M16
FHG85_RS05585	COG2843	Capsule synthesis protein
FHG85_RS05590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FHG85_RS05600	COG1254	Belongs to the acylphosphatase family
FHG85_RS05610	COG0724	RNA recognition motif
FHG85_RS05615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHG85_RS05620	COG0549	Belongs to the carbamate kinase family
FHG85_RS05630	COG1674	ftsk spoiiie
FHG85_RS05640	COG0529	Catalyzes the synthesis of activated sulfate
FHG85_RS05645	COG0175	sulfate reduction
FHG85_RS05660	COG0791	NLP P60 protein
FHG85_RS05705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FHG85_RS05715	COG4974	Belongs to the 'phage' integrase family
FHG85_RS05725	COG0793	Belongs to the peptidase S41A family
FHG85_RS05725	COG4946	Tricorn protease homolog
FHG85_RS05735	COG0339	signal peptide processing
FHG85_RS05740	COG1509	lysine 2,3-aminomutase activity
FHG85_RS05750	COG0321	lipoyl(octanoyl) transferase activity
FHG85_RS05750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FHG85_RS05760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FHG85_RS05775	COG0544	peptidyl-prolyl cis-trans isomerase activity
FHG85_RS05780	COG0545	Peptidyl-prolyl cis-trans isomerase
FHG85_RS05785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHG85_RS05790	COG0105	UTP biosynthetic process
FHG85_RS05800	COG0742	ribosomal rna small subunit methyltransferase
FHG85_RS05845	COG0511	ligase activity, forming carbon-carbon bonds
FHG85_RS05845	COG5016	pyruvate
FHG85_RS05860	COG0574	Belongs to the PEP-utilizing enzyme family
FHG85_RS05860	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FHG85_RS05865	COG1506	peptidase
FHG85_RS05865	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_RS05880	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FHG85_RS05885	COG1472	Belongs to the glycosyl hydrolase 3 family
FHG85_RS05890	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FHG85_RS05910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHG85_RS05925	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHG85_RS05930	COG0840	transmembrane signaling receptor activity
FHG85_RS05940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FHG85_RS05950	COG1979	alcohol dehydrogenase
FHG85_RS05970	COG0437	4 iron, 4 sulfur cluster binding
FHG85_RS05980	COG0626	cystathionine gamma-synthase activity
FHG85_RS05990	COG0735	belongs to the Fur family
FHG85_RS06000	COG0450	alkyl hydroperoxide reductase
FHG85_RS06010	COG0010	Belongs to the arginase family
FHG85_RS06035	COG0339	signal peptide processing
FHG85_RS06055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_RS06060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FHG85_RS06090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FHG85_RS06095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FHG85_RS06105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHG85_RS06115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FHG85_RS06125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FHG85_RS06130	COG0167	dihydroorotate dehydrogenase activity
FHG85_RS06140	COG1809	phosphosulfolactate synthase activity
FHG85_RS06160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FHG85_RS06175	COG4206	TonB-dependent receptor
FHG85_RS06175	COG1629	transport
FHG85_RS06180	COG1609	Transcriptional regulator
FHG85_RS06195	COG3279	Response regulator of the LytR AlgR family
FHG85_RS06200	COG2972	Histidine kinase
FHG85_RS06245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHG85_RS06255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHG85_RS06280	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FHG85_RS06310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHG85_RS06315	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHG85_RS06335	COG0402	S-adenosylhomocysteine deaminase activity
FHG85_RS06340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FHG85_RS06345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FHG85_RS06365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_RS06365	COG0493	'glutamate synthase
FHG85_RS06455	COG1131	(ABC) transporter
FHG85_RS06460	COG1131	(ABC) transporter
FHG85_RS06465	COG0842	Transport permease protein
FHG85_RS06470	COG0842	Transport permease protein
FHG85_RS06485	COG0243	molybdopterin cofactor binding
FHG85_RS06490	COG0437	4 iron, 4 sulfur cluster binding
FHG85_RS06515	COG0277	FAD linked oxidase domain protein
FHG85_RS06515	COG0247	lactate metabolic process
FHG85_RS06520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FHG85_RS06525	COG0280	phosphate acetyltransferase
FHG85_RS06535	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_RS06545	COG1278	Cold shock
FHG85_RS06560	COG1301	dicarboxylic acid transport
FHG85_RS06570	COG0842	Transport permease protein
FHG85_RS06570	COG1716	ATPase activity
FHG85_RS06570	COG1131	(ABC) transporter
FHG85_RS06595	COG0784	Response regulator, receiver
FHG85_RS06605	COG2202	Pas domain
FHG85_RS06605	COG2205	protein histidine kinase activity
FHG85_RS06610	COG0784	Response regulator, receiver
FHG85_RS06610	COG0835	chemotaxis
FHG85_RS06620	COG2201	protein-glutamate methylesterase activity
FHG85_RS06625	COG2201	protein-glutamate methylesterase activity
FHG85_RS06630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FHG85_RS06640	COG0840	transmembrane signaling receptor activity
FHG85_RS06645	COG0835	chemotaxis
FHG85_RS06650	COG2198	Histidine kinase
FHG85_RS06650	COG0643	Histidine kinase
FHG85_RS06655	COG2201	protein-glutamate methylesterase activity
FHG85_RS06665	COG2197	response regulator
FHG85_RS06675	COG4251	negative regulation of phosphorylation
FHG85_RS06680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FHG85_RS06690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHG85_RS06695	COG1554	hydrolase, family 65, central catalytic
FHG85_RS06700	COG0191	fructose-bisphosphate aldolase activity
FHG85_RS06705	COG0366	Alpha amylase catalytic
FHG85_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_RS06725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHG85_RS06740	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FHG85_RS06745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FHG85_RS06760	COG1028	Short-chain dehydrogenase reductase Sdr
FHG85_RS06775	COG1546	Belongs to the CinA family
FHG85_RS06775	COG1058	Belongs to the CinA family
FHG85_RS06780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FHG85_RS06785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHG85_RS06795	COG0552	protein localization to endoplasmic reticulum
FHG85_RS06800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FHG85_RS06805	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FHG85_RS06810	COG0542	response to heat
FHG85_RS06815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FHG85_RS06840	COG0709	Synthesizes selenophosphate from selenide and ATP
FHG85_RS06855	COG0425	Belongs to the sulfur carrier protein TusA family
FHG85_RS06860	COG0167	dihydroorotate dehydrogenase activity
FHG85_RS06880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHG85_RS06885	COG1032	radical SAM domain protein
FHG85_RS06890	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_RS06910	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FHG85_RS06925	COG0626	cystathionine gamma-synthase activity
FHG85_RS06930	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FHG85_RS06935	COG2234	aminopeptidase activity
FHG85_RS06940	COG0386	Belongs to the glutathione peroxidase family
FHG85_RS06985	COG0714	Associated with various cellular activities
FHG85_RS06990	COG0101	tRNA pseudouridine synthase activity
FHG85_RS07065	COG0501	Belongs to the peptidase M48B family
FHG85_RS07075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FHG85_RS07080	COG0281	malic enzyme
FHG85_RS07085	COG2135	peptidase activity
FHG85_RS07090	COG1489	DNA binding
FHG85_RS07110	COG0133	tryptophan synthase activity
FHG85_RS07140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FHG85_RS07145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FHG85_RS07150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FHG85_RS07155	COG0131	Imidazoleglycerol-phosphate dehydratase
FHG85_RS07160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FHG85_RS07165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FHG85_RS07170	COG0107	imidazoleglycerol-phosphate synthase activity
FHG85_RS07175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FHG85_RS07175	COG0140	phosphoribosyl-ATP diphosphatase activity
FHG85_RS07185	COG1278	Cold shock
FHG85_RS07190	COG1408	metallophosphoesterase
FHG85_RS07235	COG4251	negative regulation of phosphorylation
FHG85_RS07240	COG0784	Response regulator, receiver
FHG85_RS07245	COG2205	protein histidine kinase activity
FHG85_RS07245	COG2198	Histidine kinase
FHG85_RS07245	COG0784	Response regulator, receiver
FHG85_RS07250	COG1115	amino acid carrier protein
FHG85_RS07260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FHG85_RS07270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FHG85_RS07275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHG85_RS07285	COG0653	protein targeting
FHG85_RS07290	COG0018	arginyl-trna synthetase
FHG85_RS07300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHG85_RS07305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FHG85_RS07325	COG2201	protein-glutamate methylesterase activity
FHG85_RS07330	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FHG85_RS07335	COG2205	protein histidine kinase activity
FHG85_RS07335	COG0784	Response regulator, receiver
FHG85_RS07345	COG0835	chemotaxis
FHG85_RS07350	COG0643	Histidine kinase
FHG85_RS07350	COG2198	Histidine kinase
FHG85_RS07355	COG0745	RESPONSE REGULATOR receiver
FHG85_RS07375	COG0784	Response regulator, receiver
FHG85_RS07385	COG2204	response regulator
FHG85_RS07410	COG0217	transcriptional regulatory protein
FHG85_RS07435	COG1335	isochorismatase
FHG85_RS07450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHG85_RS07455	COG4771	TonB-dependent receptor
FHG85_RS07465	COG0484	heat shock protein binding
FHG85_RS07470	COG0237	dephospho-CoA kinase activity
FHG85_RS07480	COG1862	Preprotein translocase
FHG85_RS07490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHG85_RS07500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FHG85_RS07500	COG1918	ferrous iron import across plasma membrane
FHG85_RS07515	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FHG85_RS07520	COG0352	thiamine-phosphate diphosphorylase activity
FHG85_RS07525	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FHG85_RS07560	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHG85_RS07565	COG0194	GDP metabolic process
FHG85_RS07570	COG1561	YicC-like family, N-terminal region
FHG85_RS07590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FHG85_RS07600	COG0335	large ribosomal subunit rRNA binding
FHG85_RS07610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FHG85_RS07615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FHG85_RS07625	COG0778	Nitroreductase
FHG85_RS07635	COG0405	Gamma-glutamyltransferase
FHG85_RS07660	COG0567	Dehydrogenase, E1 component
FHG85_RS07710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHG85_RS07715	COG3279	Response regulator of the LytR AlgR family
FHG85_RS07745	COG1132	(ABC) transporter
FHG85_RS07750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHG85_RS07760	COG1030	water channel activity
FHG85_RS07765	COG1247	-acetyltransferase
FHG85_RS07775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHG85_RS07780	COG0436	Aminotransferase
FHG85_RS07790	COG0561	phosphatase activity
FHG85_RS07805	COG0179	Fumarylacetoacetate (FAA) hydrolase
FHG85_RS07825	COG0592	DNA-directed DNA polymerase activity
FHG85_RS07845	COG2385	sporulation resulting in formation of a cellular spore
FHG85_RS07850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FHG85_RS07860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FHG85_RS07875	COG1506	peptidase
FHG85_RS07875	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_RS07890	COG1716	ATPase activity
FHG85_RS07890	COG1131	(ABC) transporter
FHG85_RS07890	COG0842	Transport permease protein
FHG85_RS07905	COG0116	Belongs to the methyltransferase superfamily
FHG85_RS07910	COG0513	Belongs to the DEAD box helicase family
FHG85_RS07915	COG0793	Belongs to the peptidase S41A family
FHG85_RS07915	COG3409	Peptidoglycan-binding domain 1 protein
FHG85_RS07920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FHG85_RS07920	COG0519	Catalyzes the synthesis of GMP from XMP
FHG85_RS07925	COG1234	tRNA 3'-trailer cleavage
FHG85_RS07935	COG0539	negative regulation of cytoplasmic translation
FHG85_RS07945	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHG85_RS07955	COG1091	dTDP-4-dehydrorhamnose reductase activity
FHG85_RS07960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_RS07970	COG0006	proline dipeptidase activity
FHG85_RS07975	COG5002	protein histidine kinase activity
FHG85_RS07975	COG0784	Response regulator, receiver
FHG85_RS07995	COG0432	Pfam Uncharacterised protein family UPF0047
FHG85_RS08005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FHG85_RS08005	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS08005	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS08005	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_RS08020	COG2234	aminopeptidase activity
FHG85_RS08040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHG85_RS08060	COG0438	transferase activity, transferring glycosyl groups
FHG85_RS08060	COG0297	glycogen (starch) synthase activity
FHG85_RS08080	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHG85_RS08090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FHG85_RS08105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FHG85_RS08110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_RS08150	COG3250	beta-galactosidase activity
FHG85_RS08160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FHG85_RS08165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FHG85_RS08180	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FHG85_RS08185	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FHG85_RS08205	COG1418	mRNA catabolic process
FHG85_RS08220	COG0739	heme binding
FHG85_RS08245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FHG85_RS08275	COG0716	FMN binding
FHG85_RS08280	COG0501	Belongs to the peptidase M48B family
FHG85_RS08285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHG85_RS08295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_RS08310	COG0196	riboflavin kinase activity
FHG85_RS08315	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FHG85_RS08320	COG2205	protein histidine kinase activity
FHG85_RS08325	COG0745	RESPONSE REGULATOR receiver
FHG85_RS08330	COG4191	Histidine kinase
FHG85_RS08385	COG0482	sulfurtransferase activity
FHG85_RS08435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FHG85_RS08445	COG1811	Na channel or pump
FHG85_RS08455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHG85_RS08495	COG3383	formate dehydrogenase (NAD+) activity
FHG85_RS08510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FHG85_RS08515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FHG85_RS08520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FHG85_RS08525	COG2226	methyltransferase
FHG85_RS08540	COG3279	Response regulator of the LytR AlgR family
FHG85_RS08545	COG3275	phosphorelay sensor kinase activity
FHG85_RS08580	COG1131	(ABC) transporter
FHG85_RS08580	COG1716	ATPase activity
FHG85_RS08580	COG0842	Transport permease protein
FHG85_RS08590	COG0745	RESPONSE REGULATOR receiver
FHG85_RS08595	COG1629	transport
FHG85_RS08595	COG4206	TonB-dependent receptor
FHG85_RS08600	COG1404	Belongs to the peptidase S8 family
FHG85_RS08600	COG4412	M6 family metalloprotease domain protein
FHG85_RS08620	COG0167	dihydroorotate dehydrogenase activity
FHG85_RS08630	COG3118	belongs to the thioredoxin family
FHG85_RS08635	COG1611	Belongs to the LOG family
FHG85_RS08665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FHG85_RS08675	COG1131	(ABC) transporter
FHG85_RS08680	COG0514	ATP-dependent DNA helicase (RecQ)
FHG85_RS08685	COG0517	IMP dehydrogenase activity
FHG85_RS08685	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FHG85_RS08690	COG0805	protein transport
FHG85_RS08700	COG1715	Restriction endonuclease
FHG85_RS08720	COG3328	transposase activity
FHG85_RS08725	COG4221	oxidoreductase activity
FHG85_RS08740	COG2137	regulation of response to DNA damage stimulus
FHG85_RS08745	COG2890	protein-(glutamine-N5) methyltransferase activity
FHG85_RS08750	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHG85_RS08750	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FHG85_RS08755	COG0793	Belongs to the peptidase S41A family
FHG85_RS08765	COG0671	phosphoesterase, PA-phosphatase related
FHG85_RS08770	COG1803	Methylglyoxal synthase
FHG85_RS08785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FHG85_RS08820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHG85_RS08825	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FHG85_RS08845	COG1739	Uncharacterized protein family UPF0029
FHG85_RS08850	COG0540	Belongs to the ATCase OTCase family
FHG85_RS08855	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FHG85_RS08875	COG1166	arginine decarboxylase activity
FHG85_RS08890	COG3279	Response regulator of the LytR AlgR family
FHG85_RS08900	COG2972	Histidine kinase
FHG85_RS08910	COG1629	transport
FHG85_RS08910	COG4206	TonB-dependent receptor
FHG85_RS08925	COG1595	DNA-templated transcription, initiation
FHG85_RS08930	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FHG85_RS08935	COG4770	biotin carboxylase activity
FHG85_RS08945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHG85_RS08950	COG0346	lactoylglutathione lyase activity
FHG85_RS08965	COG1480	7TM receptor with intracellular HD hydrolase
FHG85_RS08970	COG0517	IMP dehydrogenase activity
FHG85_RS08970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHG85_RS08970	COG0617	tRNA 3'-terminal CCA addition
FHG85_RS08980	COG0315	cyclic pyranopterin monophosphate synthase activity
FHG85_RS08980	COG0521	Mo-molybdopterin cofactor biosynthetic process
FHG85_RS08985	COG0315	cyclic pyranopterin monophosphate synthase activity
FHG85_RS08990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FHG85_RS08995	COG0303	'Molybdopterin
FHG85_RS09010	COG2195	Cleaves the N-terminal amino acid of tripeptides
FHG85_RS09025	COG1629	transport
FHG85_RS09050	COG1629	transport
FHG85_RS09060	COG4771	TonB-dependent receptor
FHG85_RS09065	COG1595	DNA-templated transcription, initiation
FHG85_RS09080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHG85_RS09095	COG2264	protein methyltransferase activity
FHG85_RS09100	COG0149	triose-phosphate isomerase activity
FHG85_RS09105	COG0601	transmembrane transport
FHG85_RS09110	COG3956	TIGRFAM MazG family protein
FHG85_RS09120	COG1702	phosphate starvation-inducible protein PhoH
FHG85_RS09125	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FHG85_RS09140	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHG85_RS09140	COG1388	LysM domain
FHG85_RS09145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHG85_RS09150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FHG85_RS09155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FHG85_RS09160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHG85_RS09165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FHG85_RS09170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FHG85_RS09175	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FHG85_RS09180	COG0681	Belongs to the peptidase S26 family
FHG85_RS09190	COG1012	belongs to the aldehyde dehydrogenase family
FHG85_RS09195	COG2183	response to ionizing radiation
FHG85_RS09200	COG0840	transmembrane signaling receptor activity
FHG85_RS09205	COG1193	negative regulation of DNA recombination
FHG85_RS09220	COG2884	Cell division ATP-binding protein ftsE
FHG85_RS09245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FHG85_RS09260	COG4999	Histidine kinase
FHG85_RS09260	COG3850	Histidine kinase
FHG85_RS09260	COG3437	response regulator, receiver
FHG85_RS09260	COG2205	protein histidine kinase activity
FHG85_RS09265	COG4717	serine-type aminopeptidase activity
FHG85_RS09270	COG0424	maF-like protein
FHG85_RS09280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FHG85_RS09295	COG2086	electron transfer activity
FHG85_RS09300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FHG85_RS09305	COG0247	lactate metabolic process
FHG85_RS09305	COG2181	nitrate reductase activity
FHG85_RS09310	COG2181	nitrate reductase activity
FHG85_RS09310	COG0247	lactate metabolic process
FHG85_RS09315	COG1960	acyl-CoA dehydrogenase activity
FHG85_RS09325	COG0784	Response regulator, receiver
FHG85_RS09325	COG2205	protein histidine kinase activity
FHG85_RS09345	COG2169	Transcriptional regulator
FHG85_RS09375	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FHG85_RS09380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHG85_RS09390	COG1629	transport
FHG85_RS09390	COG4206	TonB-dependent receptor
FHG85_RS09400	COG1592	Rubrerythrin
FHG85_RS09410	COG0514	ATP-dependent DNA helicase (RecQ)
FHG85_RS09420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHG85_RS09440	COG1022	Amp-dependent synthetase and ligase
FHG85_RS09460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FHG85_RS09465	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHG85_RS09505	COG2502	aspartate--ammonia ligase
FHG85_RS09525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHG85_RS09535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHG85_RS09550	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHG85_RS09565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FHG85_RS09570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FHG85_RS09575	COG2045	Belongs to the ComB family
FHG85_RS09580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FHG85_RS09590	COG1366	Belongs to the anti-sigma-factor antagonist family
FHG85_RS09605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FHG85_RS09640	COG0613	PHP domain protein
FHG85_RS09670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FHG85_RS09675	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FHG85_RS09685	COG3842	ATPase activity
FHG85_RS09690	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FHG85_RS09695	COG0725	ABC transporter, periplasmic molybdate-binding protein
FHG85_RS09705	COG3123	guanosine phosphorylase activity
FHG85_RS09710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHG85_RS09760	COG0577	efflux transmembrane transporter activity
FHG85_RS09760	COG1136	(ABC) transporter
FHG85_RS09765	COG1136	(ABC) transporter
FHG85_RS09825	COG0525	valine-tRNA ligase activity
FHG85_RS09830	COG0288	reversible hydration of carbon dioxide
FHG85_RS09835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHG85_RS09840	COG0511	ligase activity, forming carbon-carbon bonds
FHG85_RS09840	COG5016	pyruvate
FHG85_RS09845	COG0439	Biotin carboxylase
FHG85_RS09870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FHG85_RS09880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHG85_RS09890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHG85_RS09930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHG85_RS09930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FHG85_RS09935	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FHG85_RS09940	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHG85_RS09945	COG0564	pseudouridine synthase activity
FHG85_RS09950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FHG85_RS09955	COG0443	Heat shock 70 kDa protein
FHG85_RS09965	COG1404	Belongs to the peptidase S8 family
FHG85_RS09970	COG1570	exodeoxyribonuclease VII activity
FHG85_RS09975	COG5002	protein histidine kinase activity
FHG85_RS09980	COG2202	Pas domain
FHG85_RS09980	COG2205	protein histidine kinase activity
FHG85_RS09985	COG1722	exodeoxyribonuclease VII activity
FHG85_RS10020	COG0747	negative chemotaxis
FHG85_RS10040	COG3850	Histidine kinase
FHG85_RS10040	COG5002	protein histidine kinase activity
FHG85_RS10060	COG1216	Glycosyl transferase, family 2
FHG85_RS10060	COG0463	Glycosyl transferase, family 2
FHG85_RS10065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHG85_RS10070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FHG85_RS10075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHG85_RS10080	COG0159	tryptophan synthase activity
FHG85_RS10085	COG0133	tryptophan synthase activity
FHG85_RS10090	COG0135	phosphoribosylanthranilate isomerase activity
FHG85_RS10095	COG0134	indole-3-glycerol-phosphate synthase activity
FHG85_RS10100	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FHG85_RS10110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHG85_RS10120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHG85_RS10125	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FHG85_RS10130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FHG85_RS10135	COG0710	3-dehydroquinate dehydratase activity
FHG85_RS10140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FHG85_RS10145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FHG85_RS10150	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FHG85_RS10160	COG0674	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS10160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FHG85_RS10160	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FHG85_RS10160	COG1013	pyruvate-flavodoxin oxidoreductase activity
FHG85_RS10165	COG3275	phosphorelay sensor kinase activity
FHG85_RS10180	COG1943	Transposase
FHG85_RS10205	COG1196	nuclear chromosome segregation
FHG85_RS10210	COG2852	Protein conserved in bacteria
FHG85_RS10235	COG1506	peptidase
FHG85_RS10235	COG0823	Involved in the tonB-independent uptake of proteins
FHG85_RS10240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHG85_RS10250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FHG85_RS10270	COG4864	UPF0365 protein
FHG85_RS10315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FHG85_RS10320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FHG85_RS10325	COG0284	orotidine-5'-phosphate decarboxylase activity
FHG85_RS10330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FHG85_RS10335	COG2234	aminopeptidase activity
FHG85_RS10355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHG85_RS10365	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FHG85_RS10370	COG1185	polyribonucleotide nucleotidyltransferase activity
FHG85_RS10375	COG1505	serine-type exopeptidase activity
FHG85_RS10380	COG1428	Deoxynucleoside kinase
FHG85_RS10395	COG0045	succinate-CoA ligase (ADP-forming) activity
FHG85_RS10410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHG85_RS10410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FHG85_RS10415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FHG85_RS10420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FHG85_RS10430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FHG85_RS10440	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FHG85_RS10460	COG0463	Glycosyl transferase, family 2
FHG85_RS10475	COG1629	transport
FHG85_RS10480	COG0702	epimerase
FHG85_RS10510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FHG85_RS10520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FHG85_RS10550	COG1355	regulation of microtubule-based process
FHG85_RS10595	COG2205	protein histidine kinase activity
FHG85_RS10600	COG0745	RESPONSE REGULATOR receiver
FHG85_RS10610	COG0459	protein refolding
FHG85_RS10615	COG1610	YqeY-like protein
FHG85_RS10625	COG1272	protein, Hemolysin III
FHG85_RS10660	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FHG85_RS10685	COG2207	Transcriptional regulator
FHG85_RS10685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FHG85_RS10730	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FHG85_RS10735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FHG85_RS10740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FHG85_RS10745	COG0193	aminoacyl-tRNA hydrolase activity
FHG85_RS10750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FHG85_RS10765	COG3142	Participates in the control of copper homeostasis
FHG85_RS10775	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FHG85_RS10780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FHG85_RS10785	COG4770	biotin carboxylase activity
FHG85_RS10790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FHG85_RS10800	COG0343	queuine tRNA-ribosyltransferase activity
FHG85_RS10805	COG0101	tRNA pseudouridine synthase activity
FHG85_RS10820	COG0463	Glycosyl transferase, family 2
FHG85_RS10825	COG0778	Nitroreductase
FHG85_RS10830	COG1418	mRNA catabolic process
FHG85_RS10835	COG0248	Ppx GppA phosphatase
FHG85_RS10895	COG0481	GTPase activity
FHG85_RS10910	COG1160	GTP binding
FHG85_RS10915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHG85_RS10920	COG1187	pseudouridine synthase activity
FHG85_RS10925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FHG85_RS10935	COG1136	(ABC) transporter
FHG85_RS10965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHG85_RS10970	COG0798	PFAM Bile acid sodium symporter
FHG85_RS10985	COG2205	protein histidine kinase activity
FHG85_RS10985	COG0784	Response regulator, receiver
FHG85_RS10990	COG0259	pyridoxamine-phosphate oxidase activity
FHG85_RS11010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FHG85_RS11015	COG4191	Histidine kinase
FHG85_RS11050	COG1309	transcriptional regulator
FHG85_RS11060	COG0513	Belongs to the DEAD box helicase family
FHG85_RS11065	COG1215	transferase activity, transferring glycosyl groups
FHG85_RS11070	COG1595	DNA-templated transcription, initiation
FHG85_RS11075	COG0357	Ribosomal RNA small subunit methyltransferase G
FHG85_RS11080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FHG85_RS11085	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FHG85_RS11090	COG2815	serine threonine protein kinase
FHG85_RS11090	COG0515	serine threonine protein kinase
FHG85_RS11100	COG0564	pseudouridine synthase activity
FHG85_RS11120	COG1752	Esterase of the alpha-beta hydrolase superfamily
FHG85_RS11125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHG85_RS11140	COG0776	regulation of translation
FHG85_RS11145	COG1530	ribonuclease E activity
FHG85_RS11150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FHG85_RS11155	COG3537	Alpha-1,2-mannosidase
FHG85_RS11170	COG1940	carbohydrate kinase activity
FHG85_RS11180	COG1609	Transcriptional regulator
FHG85_RS11210	COG0252	asparaginase activity
FHG85_RS11215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FHG85_RS11225	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHG85_RS11230	COG4232	protein-disulfide reductase activity
FHG85_RS11235	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FHG85_RS11240	COG1012	belongs to the aldehyde dehydrogenase family
FHG85_RS11250	COG2832	Protein of unknown function (DUF454)
FHG85_RS11255	COG1181	Belongs to the D-alanine--D-alanine ligase family
FHG85_RS11275	COG1473	amidohydrolase
FHG85_RS11280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FHG85_RS11285	COG2205	protein histidine kinase activity
FHG85_RS11285	COG0745	RESPONSE REGULATOR receiver
FHG85_RS11285	COG3292	Two component regulator propeller
FHG85_RS11290	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FHG85_RS11295	COG0148	phosphopyruvate hydratase activity
FHG85_RS11300	COG0203	ribosomal protein L17
FHG85_RS11305	COG0202	RNA polymerase activity
FHG85_RS11310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FHG85_RS11315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FHG85_RS11320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FHG85_RS11325	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FHG85_RS11330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FHG85_RS11345	COG0200	Binds to the 23S rRNA
FHG85_RS11350	COG1841	ribosomal large subunit assembly
FHG85_RS11355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FHG85_RS11360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FHG85_RS11365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FHG85_RS11370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FHG85_RS11375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHG85_RS11380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FHG85_RS11385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FHG85_RS11390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FHG85_RS11395	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FHG85_RS11400	COG0255	Belongs to the universal ribosomal protein uL29 family
FHG85_RS11405	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FHG85_RS11410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FHG85_RS11415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FHG85_RS11420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FHG85_RS11425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FHG85_RS11430	COG0089	rRNA binding
FHG85_RS11435	COG0088	Forms part of the polypeptide exit tunnel
FHG85_RS11440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FHG85_RS11445	COG0051	transcription antitermination factor activity, RNA binding
FHG85_RS11450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHG85_RS11455	COG0049	tRNA binding
FHG85_RS11460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FHG85_RS11465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHG85_RS11470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FHG85_RS11475	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
FHG85_RS11525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHG85_RS11525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHG85_RS11530	COG0195	Participates in both transcription termination and antitermination
FHG85_RS11535	COG0779	Required for maturation of 30S ribosomal subunits
FHG85_RS11540	COG0438	transferase activity, transferring glycosyl groups
FHG85_RS11545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FHG85_RS11550	COG3591	Belongs to the peptidase S1B family
FHG85_RS11580	COG2205	protein histidine kinase activity
FHG85_RS11580	COG5002	protein histidine kinase activity
FHG85_RS11580	COG0784	Response regulator, receiver
FHG85_RS11600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FHG85_RS11610	COG4953	penicillin-binding protein 1C
FHG85_RS11615	COG2373	Large extracellular alpha-helical protein
FHG85_RS11625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHG85_RS11625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHG85_RS11665	COG2171	N-acyltransferase activity
FHG85_RS11670	COG3959	Transketolase, thiamine diphosphate binding domain
FHG85_RS11680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHG85_RS11705	COG2166	iron-sulfur cluster assembly
FHG85_RS11710	COG2151	metal-sulfur cluster biosynthetic enzyme
FHG85_RS11730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FHG85_RS11735	COG0436	Aminotransferase
FHG85_RS11755	COG2204	response regulator
FHG85_RS11785	COG2205	protein histidine kinase activity
FHG85_RS11805	COG1695	Transcriptional regulator
FHG85_RS11820	COG1696	Membrane protein involved in D-alanine export
FHG85_RS11835	COG1393	Belongs to the ArsC family
FHG85_RS11845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FHG85_RS11845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FHG85_RS11850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHG85_RS11855	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHG85_RS11860	COG1968	undecaprenyl-diphosphatase activity
FHG85_RS11870	COG2177	Part of the ABC transporter FtsEX involved in
FHG85_RS11880	COG0423	glycine-tRNA ligase activity
FHG85_RS11895	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FHG85_RS11900	COG4948	Mandelate Racemase Muconate Lactonizing
FHG85_RS11905	COG3250	beta-galactosidase activity
FHG85_RS11920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHG85_RS11925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_RS11925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_RS11930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FHG85_RS11940	COG1475	DNA binding
FHG85_RS11945	COG1192	Involved in chromosome partitioning
FHG85_RS11950	COG1597	lipid kinase activity
FHG85_RS11960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FHG85_RS11965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FHG85_RS11970	COG2211	Major facilitator Superfamily
FHG85_RS12000	COG0175	sulfate reduction
FHG85_RS12015	COG0840	transmembrane signaling receptor activity
FHG85_RS12030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FHG85_RS12035	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FHG85_RS12035	COG3264	Mechanosensitive ion channel
FHG85_RS12055	COG1011	Hydrolase
FHG85_RS12075	COG1271	oxidase subunit
FHG85_RS12080	COG1294	oxidase, subunit
FHG85_RS12085	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FHG85_RS12090	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHG85_RS12095	COG1183	phosphatidylcholine synthase activity
FHG85_RS12100	COG0671	phosphoesterase, PA-phosphatase related
FHG85_RS12105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHG85_RS12110	COG0563	adenylate kinase activity
FHG85_RS12120	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FHG85_RS12145	COG4989	oxidoreductase activity
FHG85_RS12170	COG0402	S-adenosylhomocysteine deaminase activity
FHG85_RS12175	COG0731	radical SAM domain protein
FHG85_RS12175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FHG85_RS12205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FHG85_RS12210	COG0416	fatty acid biosynthetic process
FHG85_RS12215	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FHG85_RS12245	COG1428	Deoxynucleoside kinase
FHG85_RS12255	COG0156	8-amino-7-oxononanoate synthase activity
FHG85_RS12265	COG1214	PFAM Peptidase M22, glycoprotease
FHG85_RS12345	COG3179	chitinase
FHG85_RS12355	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FHG85_RS12390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHG85_RS12410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FHG85_RS12430	COG1629	transport
FHG85_RS12440	COG0698	ribose 5-phosphate isomerase
FHG85_RS12445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHG85_RS12465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHG85_RS12465	COG2205	protein histidine kinase activity
FHG85_RS12475	COG1381	Involved in DNA repair and RecF pathway recombination
FHG85_RS12485	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FHG85_RS12505	COG3829	transcription factor binding
FHG85_RS12505	COG3290	protein histidine kinase activity
FHG85_RS12515	COG2204	response regulator
FHG85_RS12550	COG1595	DNA-templated transcription, initiation
FHG85_RS12555	COG0151	Belongs to the GarS family
FHG85_RS12565	COG2176	DNA-directed DNA polymerase activity
FHG85_RS12575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FHG85_RS12585	COG0720	synthase
FHG85_RS12595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHG85_RS12625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHG85_RS12630	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHG85_RS12645	COG0793	Belongs to the peptidase S41A family
FHG85_RS12650	COG2131	deaminase
FHG85_RS12660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FHG85_RS12700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FHG85_RS12710	COG0012	GTP binding
FHG85_RS12715	COG0784	Response regulator, receiver
FHG85_RS12715	COG2205	protein histidine kinase activity
FHG85_RS12715	COG2198	Histidine kinase
FHG85_RS12720	COG0009	L-threonylcarbamoyladenylate synthase
FHG85_RS12730	COG1216	Glycosyl transferase, family 2
FHG85_RS12730	COG0463	Glycosyl transferase, family 2
FHG85_RS12740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FHG85_RS12745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FHG85_RS12760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHG85_RS12765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHG85_RS12770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FHG85_RS12775	COG0571	ribonuclease III activity
FHG85_RS12785	COG0840	transmembrane signaling receptor activity
FHG85_RS12815	COG1730	sister chromatid segregation
FHG85_RS12835	COG0006	proline dipeptidase activity
FHG85_RS12850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHG85_RS12870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FHG85_RS12875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FHG85_RS12915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHG85_RS12920	COG2356	endonuclease I
FHG85_RS12925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHG85_RS12935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FHG85_RS12940	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FHG85_RS12950	COG2431	L-lysine efflux transmembrane transporter activity
FHG85_RS12955	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FHG85_RS12965	COG1522	sequence-specific DNA binding
FHG85_RS12985	COG1490	D-aminoacyl-tRNA deacylase activity
FHG85_RS13010	COG0739	heme binding
FHG85_RS13015	COG0826	peptidase U32
FHG85_RS13025	COG0859	PFAM glycosyl transferase family 9
FHG85_RS13030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHG85_RS13035	COG1162	GTPase activity
FHG85_RS13045	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FHG85_RS13065	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHG85_RS13070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FHG85_RS13075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FHG85_RS13080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_RS13085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FHG85_RS13090	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FHG85_RS13095	COG0356	it plays a direct role in the translocation of protons across the membrane
FHG85_RS13140	COG5002	protein histidine kinase activity
FHG85_RS13145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FHG85_RS13150	COG0594	ribonuclease P activity
FHG85_RS13165	COG0322	excinuclease ABC activity
FHG85_RS13170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FHG85_RS13175	COG0445	tRNA wobble uridine modification
FHG85_RS13180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA