locus-tag	class	description
CGC64_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CGC64_RS00010	COG0778	Nitroreductase
CGC64_RS00020	COG1640	4-alpha-glucanotransferase
CGC64_RS00025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CGC64_RS00045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGC64_RS00050	COG1022	Amp-dependent synthetase and ligase
CGC64_RS00090	COG0359	binds to the 23S rRNA
CGC64_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CGC64_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
CGC64_RS00120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGC64_RS00125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGC64_RS00150	COG1131	(ABC) transporter
CGC64_RS00165	COG2431	L-lysine efflux transmembrane transporter activity
CGC64_RS00185	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CGC64_RS00195	COG4771	TonB-dependent receptor
CGC64_RS00225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CGC64_RS00230	COG0802	atpase or kinase
CGC64_RS00245	COG0714	Associated with various cellular activities
CGC64_RS00280	COG3118	belongs to the thioredoxin family
CGC64_RS00295	COG0688	phosphatidylethanolamine metabolic process
CGC64_RS00300	COG1183	phosphatidylcholine synthase activity
CGC64_RS00320	COG0792	nuclease activity
CGC64_RS00345	COG0534	Mate efflux family protein
CGC64_RS00350	COG0528	UMP kinase activity
CGC64_RS00360	COG0233	cytoplasmic translational termination
CGC64_RS00365	COG1162	GTPase activity
CGC64_RS00375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CGC64_RS00390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC64_RS00390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CGC64_RS00400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CGC64_RS00415	COG1629	transport
CGC64_RS00425	COG4206	TonB-dependent receptor
CGC64_RS00425	COG1629	transport
CGC64_RS00435	COG2095	MarC family integral membrane protein
CGC64_RS00450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CGC64_RS00460	COG1785	Belongs to the alkaline phosphatase family
CGC64_RS00470	COG4206	TonB-dependent receptor
CGC64_RS00470	COG1629	transport
CGC64_RS00475	COG1435	thymidine kinase activity
CGC64_RS00480	COG0628	permease
CGC64_RS00500	COG2433	Pfam Transposase IS66
CGC64_RS00550	COG3973	AAA domain
CGC64_RS00585	COG0456	acetyltransferase
CGC64_RS00595	COG4974	Belongs to the 'phage' integrase family
CGC64_RS00600	COG0582	viral genome integration into host DNA
CGC64_RS00630	COG2223	nitrite transmembrane transporter activity
CGC64_RS00640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CGC64_RS00645	COG2197	response regulator
CGC64_RS00660	COG0784	Response regulator, receiver
CGC64_RS00660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CGC64_RS00660	COG2198	Histidine kinase
CGC64_RS00660	COG2205	protein histidine kinase activity
CGC64_RS00695	COG0702	epimerase
CGC64_RS00700	COG4771	TonB-dependent receptor
CGC64_RS00705	COG0745	RESPONSE REGULATOR receiver
CGC64_RS00705	COG2205	protein histidine kinase activity
CGC64_RS00705	COG3292	Two component regulator propeller
CGC64_RS00730	COG0589	response to stress
CGC64_RS00730	COG0475	glutathione-regulated potassium exporter activity
CGC64_RS00745	COG0745	RESPONSE REGULATOR receiver
CGC64_RS00745	COG2205	protein histidine kinase activity
CGC64_RS00745	COG3292	Two component regulator propeller
CGC64_RS00750	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CGC64_RS00755	COG4771	TonB-dependent receptor
CGC64_RS00835	COG0534	Mate efflux family protein
CGC64_RS00850	COG0826	peptidase U32
CGC64_RS00855	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CGC64_RS00865	COG0436	Aminotransferase
CGC64_RS00870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CGC64_RS00935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CGC64_RS00970	COG4974	Belongs to the 'phage' integrase family
CGC64_RS00985	COG4206	TonB-dependent receptor
CGC64_RS00985	COG1629	transport
CGC64_RS00990	COG0702	epimerase
CGC64_RS00995	COG3250	beta-galactosidase activity
CGC64_RS01000	COG3420	alginic acid biosynthetic process
CGC64_RS01005	COG0519	Catalyzes the synthesis of GMP from XMP
CGC64_RS01010	COG5002	protein histidine kinase activity
CGC64_RS01015	COG2205	protein histidine kinase activity
CGC64_RS01025	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CGC64_RS01035	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CGC64_RS01045	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CGC64_RS01085	COG2204	response regulator
CGC64_RS01090	COG0446	pyridine nucleotide-disulphide oxidoreductase
CGC64_RS01110	COG1472	Belongs to the glycosyl hydrolase 3 family
CGC64_RS01115	COG0737	Belongs to the 5'-nucleotidase family
CGC64_RS01125	COG0335	large ribosomal subunit rRNA binding
CGC64_RS01135	COG1940	carbohydrate kinase activity
CGC64_RS01140	COG0577	efflux transmembrane transporter activity
CGC64_RS01140	COG1136	(ABC) transporter
CGC64_RS01145	COG0577	efflux transmembrane transporter activity
CGC64_RS01145	COG1136	(ABC) transporter
CGC64_RS01150	COG1136	(ABC) transporter
CGC64_RS01150	COG0577	efflux transmembrane transporter activity
CGC64_RS01165	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGC64_RS01165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CGC64_RS01170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGC64_RS01190	COG2996	Protein conserved in bacteria
CGC64_RS01195	COG0039	L-malate dehydrogenase activity
CGC64_RS01205	COG2217	Heavy metal translocating P-type atpase
CGC64_RS01220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CGC64_RS01225	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CGC64_RS01230	COG0509	glycine decarboxylation via glycine cleavage system
CGC64_RS01245	COG0006	proline dipeptidase activity
CGC64_RS01260	COG1283	sodium-dependent phosphate transmembrane transporter activity
CGC64_RS01270	COG1773	rubredoxin
CGC64_RS01280	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CGC64_RS01285	COG1011	Hydrolase
CGC64_RS01290	COG0196	riboflavin kinase activity
CGC64_RS01295	COG1266	CAAX protease self-immunity
CGC64_RS01305	COG0612	Peptidase, M16
CGC64_RS01325	COG2166	iron-sulfur cluster assembly
CGC64_RS01330	COG2234	aminopeptidase activity
CGC64_RS01335	COG1619	proteins homologs of microcin C7 resistance protein MccF
CGC64_RS01345	COG0280	phosphate acetyltransferase
CGC64_RS01350	COG3426	butyrate kinase activity
CGC64_RS01365	COG1185	polyribonucleotide nucleotidyltransferase activity
CGC64_RS01375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CGC64_RS01395	COG1595	DNA-templated transcription, initiation
CGC64_RS01400	COG0076	glutamate decarboxylase activity
CGC64_RS01405	COG2066	Belongs to the glutaminase family
CGC64_RS01415	COG0531	amino acid
CGC64_RS01445	COG1725	Transcriptional regulator
CGC64_RS01455	COG1131	(ABC) transporter
CGC64_RS01530	COG0673	inositol 2-dehydrogenase activity
CGC64_RS01545	COG3420	alginic acid biosynthetic process
CGC64_RS01560	COG0702	epimerase
CGC64_RS01565	COG4771	TonB-dependent receptor
CGC64_RS01580	COG0667	Aldo Keto reductase
CGC64_RS01585	COG1696	Membrane protein involved in D-alanine export
CGC64_RS01620	COG1309	transcriptional regulator
CGC64_RS01630	COG2986	histidine ammonia-lyase
CGC64_RS01655	COG0203	ribosomal protein L17
CGC64_RS01660	COG0202	RNA polymerase activity
CGC64_RS01665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CGC64_RS01670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CGC64_RS01675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CGC64_RS01680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CGC64_RS01685	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CGC64_RS01700	COG0200	Binds to the 23S rRNA
CGC64_RS01705	COG1841	ribosomal large subunit assembly
CGC64_RS01710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CGC64_RS01715	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CGC64_RS01720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CGC64_RS01725	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CGC64_RS01730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CGC64_RS01735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CGC64_RS01740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CGC64_RS01745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CGC64_RS01750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CGC64_RS01755	COG0255	Belongs to the universal ribosomal protein uL29 family
CGC64_RS01760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CGC64_RS01765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CGC64_RS01770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CGC64_RS01775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CGC64_RS01780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CGC64_RS01785	COG0089	rRNA binding
CGC64_RS01790	COG0088	Forms part of the polypeptide exit tunnel
CGC64_RS01795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CGC64_RS01800	COG0051	transcription antitermination factor activity, RNA binding
CGC64_RS01805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CGC64_RS01810	COG0049	tRNA binding
CGC64_RS01815	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CGC64_RS01825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CGC64_RS01830	COG0085	RNA polymerase activity
CGC64_RS01835	COG0222	ribosome binding
CGC64_RS01840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CGC64_RS01845	COG0081	regulation of translation
CGC64_RS01850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CGC64_RS01860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CGC64_RS01870	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CGC64_RS01900	COG4974	Belongs to the 'phage' integrase family
CGC64_RS01905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CGC64_RS01915	COG0006	proline dipeptidase activity
CGC64_RS01920	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CGC64_RS01930	COG3118	belongs to the thioredoxin family
CGC64_RS01940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGC64_RS01950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CGC64_RS01960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CGC64_RS01975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGC64_RS01980	COG1027	Aspartate ammonia-lyase
CGC64_RS01985	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CGC64_RS01990	COG0252	asparaginase activity
CGC64_RS02015	COG4771	TonB-dependent receptor
CGC64_RS02030	COG3119	arylsulfatase activity
CGC64_RS02060	COG4974	Belongs to the 'phage' integrase family
CGC64_RS02080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CGC64_RS02125	COG2096	Adenosyltransferase
CGC64_RS02155	COG4974	Belongs to the 'phage' integrase family
CGC64_RS02160	COG4804	nuclease activity
CGC64_RS02165	COG4804	nuclease activity
CGC64_RS02175	COG1051	belongs to the nudix hydrolase family
CGC64_RS02180	COG0546	phosphoglycolate phosphatase activity
CGC64_RS02205	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CGC64_RS02205	COG0662	Cupin 2, conserved barrel domain protein
CGC64_RS02210	COG0318	PFAM AMP-dependent synthetase and ligase
CGC64_RS02215	COG1396	sequence-specific DNA binding
CGC64_RS02220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CGC64_RS02225	COG1217	gtp-binding protein TYPA
CGC64_RS02240	COG2059	Chromate
CGC64_RS02250	COG5434	Belongs to the glycosyl hydrolase 28 family
CGC64_RS02270	COG1629	transport
CGC64_RS02300	COG1595	DNA-templated transcription, initiation
CGC64_RS02305	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CGC64_RS02310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CGC64_RS02340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CGC64_RS02350	COG0793	Belongs to the peptidase S41A family
CGC64_RS02355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC64_RS02395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC64_RS02400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CGC64_RS02410	COG1629	transport
CGC64_RS02415	COG0702	epimerase
CGC64_RS02440	COG4948	Mandelate Racemase Muconate Lactonizing
CGC64_RS02450	COG3634	alkyl hydroperoxide reductase activity
CGC64_RS02460	COG1629	transport
CGC64_RS02465	COG0702	epimerase
CGC64_RS02475	COG0745	RESPONSE REGULATOR receiver
CGC64_RS02475	COG2205	protein histidine kinase activity
CGC64_RS02475	COG3292	Two component regulator propeller
CGC64_RS02480	COG1501	Belongs to the glycosyl hydrolase 31 family
CGC64_RS02490	COG2816	NAD+ diphosphatase activity
CGC64_RS02510	COG1629	transport
CGC64_RS02520	COG4771	TonB-dependent receptor
CGC64_RS02545	COG2205	protein histidine kinase activity
CGC64_RS02545	COG3292	Two component regulator propeller
CGC64_RS02545	COG0745	RESPONSE REGULATOR receiver
CGC64_RS02545	COG2205	protein histidine kinase activity
CGC64_RS02545	COG0745	RESPONSE REGULATOR receiver
CGC64_RS02545	COG3292	Two component regulator propeller
CGC64_RS02560	COG0018	arginyl-trna synthetase
CGC64_RS02570	COG0705	Rhomboid family
CGC64_RS02585	COG0339	signal peptide processing
CGC64_RS02590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CGC64_RS02600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CGC64_RS02600	COG0674	pyruvate-flavodoxin oxidoreductase activity
CGC64_RS02605	COG1013	pyruvate-flavodoxin oxidoreductase activity
CGC64_RS02615	COG4591	ABC-type transport system involved in lipoprotein release permease component
CGC64_RS02620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CGC64_RS02640	COG4974	Belongs to the 'phage' integrase family
CGC64_RS02665	COG0606	chelatase, subunit chli
CGC64_RS02680	COG3940	Belongs to the glycosyl hydrolase 43 family
CGC64_RS02685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS02690	COG3119	arylsulfatase activity
CGC64_RS02710	COG4771	TonB-dependent receptor
CGC64_RS02720	COG3250	beta-galactosidase activity
CGC64_RS02735	COG0702	epimerase
CGC64_RS02740	COG1629	transport
CGC64_RS02740	COG4206	TonB-dependent receptor
CGC64_RS02745	COG0745	RESPONSE REGULATOR receiver
CGC64_RS02745	COG2205	protein histidine kinase activity
CGC64_RS02745	COG3292	Two component regulator propeller
CGC64_RS02820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGC64_RS02820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGC64_RS02840	COG3475	LICD family
CGC64_RS02855	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS02870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS02885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS02905	COG3250	beta-galactosidase activity
CGC64_RS02925	COG1629	transport
CGC64_RS02930	COG3250	beta-galactosidase activity
CGC64_RS02940	COG0745	RESPONSE REGULATOR receiver
CGC64_RS02940	COG2205	protein histidine kinase activity
CGC64_RS02940	COG3292	Two component regulator propeller
CGC64_RS02960	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CGC64_RS02965	COG0545	Peptidyl-prolyl cis-trans isomerase
CGC64_RS02970	COG0545	Peptidyl-prolyl cis-trans isomerase
CGC64_RS02995	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CGC64_RS03030	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CGC64_RS03035	COG4771	TonB-dependent receptor
CGC64_RS03040	COG0702	epimerase
CGC64_RS03045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGC64_RS03070	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CGC64_RS03075	COG3409	Peptidoglycan-binding domain 1 protein
CGC64_RS03075	COG0793	Belongs to the peptidase S41A family
CGC64_RS03085	COG3119	arylsulfatase activity
CGC64_RS03100	COG1053	succinate dehydrogenase
CGC64_RS03105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CGC64_RS03145	COG0582	viral genome integration into host DNA
CGC64_RS03185	COG0826	peptidase U32
CGC64_RS03190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC64_RS03205	COG0557	exoribonuclease II activity
CGC64_RS03215	COG1472	Belongs to the glycosyl hydrolase 3 family
CGC64_RS03230	COG1917	Cupin 2, conserved barrel domain protein
CGC64_RS03235	COG1073	alpha beta
CGC64_RS03240	COG2814	Major facilitator Superfamily
CGC64_RS03245	COG1012	belongs to the aldehyde dehydrogenase family
CGC64_RS03250	COG0012	GTP binding
CGC64_RS03255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CGC64_RS03260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CGC64_RS03265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CGC64_RS03270	COG3250	beta-galactosidase activity
CGC64_RS03285	COG1629	transport
CGC64_RS03285	COG4206	TonB-dependent receptor
CGC64_RS03300	COG0697	spore germination
CGC64_RS03310	COG0495	leucyl-tRNA aminoacylation
CGC64_RS03315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGC64_RS03320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CGC64_RS03325	COG1360	Flagellar Motor Protein
CGC64_RS03335	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS03345	COG0745	RESPONSE REGULATOR receiver
CGC64_RS03345	COG3292	Two component regulator propeller
CGC64_RS03345	COG2205	protein histidine kinase activity
CGC64_RS03370	COG4771	TonB-dependent receptor
CGC64_RS03375	COG0561	phosphatase activity
CGC64_RS03380	COG4771	TonB-dependent receptor
CGC64_RS03395	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CGC64_RS03430	COG4771	TonB-dependent receptor
CGC64_RS03455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS03465	COG0731	radical SAM domain protein
CGC64_RS03465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGC64_RS03480	COG4771	TonB-dependent receptor
CGC64_RS03525	COG1629	transport
CGC64_RS03545	COG3119	arylsulfatase activity
CGC64_RS03550	COG3119	arylsulfatase activity
CGC64_RS03555	COG3119	arylsulfatase activity
CGC64_RS03560	COG3119	arylsulfatase activity
CGC64_RS03570	COG3119	arylsulfatase activity
CGC64_RS03580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CGC64_RS03585	COG0659	secondary active sulfate transmembrane transporter activity
CGC64_RS03590	COG1592	Rubrerythrin
CGC64_RS03630	COG0427	acetyl-CoA hydrolase
CGC64_RS03640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGC64_RS03650	COG2177	Part of the ABC transporter FtsEX involved in
CGC64_RS03660	COG1968	undecaprenyl-diphosphatase activity
CGC64_RS03665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CGC64_RS03670	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CGC64_RS03675	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CGC64_RS03685	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CGC64_RS03735	COG0594	ribonuclease P activity
CGC64_RS03740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CGC64_RS03745	COG0084	hydrolase, TatD family'
CGC64_RS03750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CGC64_RS03765	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CGC64_RS03770	COG1028	Short-chain dehydrogenase reductase Sdr
CGC64_RS03830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CGC64_RS03845	COG1121	(ABC) transporter
CGC64_RS03855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CGC64_RS03855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CGC64_RS03875	COG0823	Involved in the tonB-independent uptake of proteins
CGC64_RS03875	COG1506	peptidase
CGC64_RS03880	COG0116	Belongs to the methyltransferase superfamily
CGC64_RS03880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CGC64_RS03885	COG1045	serine acetyltransferase
CGC64_RS03890	COG3275	phosphorelay sensor kinase activity
CGC64_RS03895	COG3279	Response regulator of the LytR AlgR family
CGC64_RS03905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGC64_RS03905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CGC64_RS03910	COG0142	geranyltranstransferase activity
CGC64_RS03925	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CGC64_RS03930	COG1694	Mazg nucleotide pyrophosphohydrolase
CGC64_RS03935	COG1490	D-aminoacyl-tRNA deacylase activity
CGC64_RS03940	COG0322	excinuclease ABC activity
CGC64_RS03945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGC64_RS03950	COG0445	tRNA wobble uridine modification
CGC64_RS03965	COG4771	TonB-dependent receptor
CGC64_RS04005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CGC64_RS04010	COG2715	membrane protein required for spore maturation
CGC64_RS04015	COG2255	four-way junction helicase activity
CGC64_RS04020	COG2852	Protein conserved in bacteria
CGC64_RS04035	COG3591	Belongs to the peptidase S1B family
CGC64_RS04040	COG0513	Belongs to the DEAD box helicase family
CGC64_RS04060	COG0612	Peptidase, M16
CGC64_RS04070	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS04075	COG1629	transport
CGC64_RS04100	COG0673	inositol 2-dehydrogenase activity
CGC64_RS04105	COG3292	Two component regulator propeller
CGC64_RS04105	COG0745	RESPONSE REGULATOR receiver
CGC64_RS04105	COG2205	protein histidine kinase activity
CGC64_RS04115	COG0681	Belongs to the peptidase S26 family
CGC64_RS04125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CGC64_RS04135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS04160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CGC64_RS04165	COG4771	TonB-dependent receptor
CGC64_RS04200	COG3119	arylsulfatase activity
CGC64_RS04205	COG0745	RESPONSE REGULATOR receiver
CGC64_RS04205	COG3292	Two component regulator propeller
CGC64_RS04205	COG2205	protein histidine kinase activity
CGC64_RS04205	COG0745	RESPONSE REGULATOR receiver
CGC64_RS04205	COG2205	protein histidine kinase activity
CGC64_RS04205	COG3292	Two component regulator propeller
CGC64_RS04215	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CGC64_RS04220	COG1538	Outer membrane efflux protein
CGC64_RS04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS04235	COG3250	beta-galactosidase activity
CGC64_RS04245	COG4771	TonB-dependent receptor
CGC64_RS04260	COG0702	epimerase
CGC64_RS04280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS04285	COG3119	arylsulfatase activity
CGC64_RS04290	COG5492	domain, Protein
CGC64_RS04295	COG0215	cysteine-tRNA ligase activity
CGC64_RS04300	COG0561	phosphatase activity
CGC64_RS04310	COG0482	sulfurtransferase activity
CGC64_RS04320	COG0205	6-phosphofructokinase activity
CGC64_RS04325	COG0571	ribonuclease III activity
CGC64_RS04330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CGC64_RS04335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CGC64_RS04355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CGC64_RS04370	COG0562	UDP-galactopyranose mutase
CGC64_RS04375	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS04390	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS04395	COG3475	LICD family
CGC64_RS04400	COG4750	Nucleotidyl transferase
CGC64_RS04420	COG1216	Glycosyl transferase, family 2
CGC64_RS04425	COG0562	UDP-galactopyranose mutase
CGC64_RS04430	COG1216	Glycosyl transferase, family 2
CGC64_RS04445	COG1215	transferase activity, transferring glycosyl groups
CGC64_RS04485	COG0463	Glycosyl transferase, family 2
CGC64_RS04520	COG1132	(ABC) transporter
CGC64_RS04525	COG3119	arylsulfatase activity
CGC64_RS04535	COG0463	Glycosyl transferase, family 2
CGC64_RS04545	COG3341	Caulimovirus viroplasmin
CGC64_RS04545	COG0328	RNA-DNA hybrid ribonuclease activity
CGC64_RS04555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CGC64_RS04565	COG0326	Molecular chaperone. Has ATPase activity
CGC64_RS04575	COG1166	arginine decarboxylase activity
CGC64_RS04580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CGC64_RS04605	COG0779	Required for maturation of 30S ribosomal subunits
CGC64_RS04610	COG0195	Participates in both transcription termination and antitermination
CGC64_RS04615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CGC64_RS04625	COG0719	Fe-S assembly protein
CGC64_RS04630	COG0396	ATPase activity
CGC64_RS04635	COG0719	Fe-S assembly protein
CGC64_RS04640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CGC64_RS04645	COG0393	Putative heavy-metal-binding
CGC64_RS04650	COG3119	arylsulfatase activity
CGC64_RS04660	COG1629	transport
CGC64_RS04660	COG4206	TonB-dependent receptor
CGC64_RS04670	COG1595	DNA-templated transcription, initiation
CGC64_RS04690	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CGC64_RS04695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CGC64_RS04715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CGC64_RS04735	COG0187	DNA topoisomerase II activity
CGC64_RS04740	COG0268	Binds directly to 16S ribosomal RNA
CGC64_RS04765	COG1381	Involved in DNA repair and RecF pathway recombination
CGC64_RS04820	COG1610	YqeY-like protein
CGC64_RS04825	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CGC64_RS04830	COG0849	cell division
CGC64_RS04840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CGC64_RS04845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CGC64_RS04850	COG0772	Belongs to the SEDS family
CGC64_RS04855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CGC64_RS04860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CGC64_RS04865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CGC64_RS04880	COG0275	rRNA processing
CGC64_RS04885	COG2001	Belongs to the MraZ family
CGC64_RS04890	COG1595	DNA-templated transcription, initiation
CGC64_RS04905	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CGC64_RS04910	COG0756	dUTP diphosphatase activity
CGC64_RS04925	COG4942	peptidase
CGC64_RS04930	COG2017	converts alpha-aldose to the beta-anomer
CGC64_RS04935	COG2818	Glycosylase
CGC64_RS05000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CGC64_RS05005	COG1022	Amp-dependent synthetase and ligase
CGC64_RS05010	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CGC64_RS05020	COG2954	triphosphatase activity
CGC64_RS05095	COG0561	phosphatase activity
CGC64_RS05100	COG4771	TonB-dependent receptor
CGC64_RS05135	COG0423	glycine-tRNA ligase activity
CGC64_RS05145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CGC64_RS05160	COG2211	Major facilitator Superfamily
CGC64_RS05170	COG1216	Glycosyl transferase, family 2
CGC64_RS05170	COG0463	Glycosyl transferase, family 2
CGC64_RS05175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CGC64_RS05205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CGC64_RS05210	COG0475	glutathione-regulated potassium exporter activity
CGC64_RS05210	COG0589	response to stress
CGC64_RS05215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CGC64_RS05220	COG1136	(ABC) transporter
CGC64_RS05230	COG0733	neurotransmitter:sodium symporter activity
CGC64_RS05240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CGC64_RS05245	COG2205	protein histidine kinase activity
CGC64_RS05250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CGC64_RS05255	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CGC64_RS05275	COG1082	Xylose isomerase domain protein TIM barrel
CGC64_RS05280	COG3507	Belongs to the glycosyl hydrolase 43 family
CGC64_RS05285	COG3292	Two component regulator propeller
CGC64_RS05285	COG2205	protein histidine kinase activity
CGC64_RS05285	COG0745	RESPONSE REGULATOR receiver
CGC64_RS05290	COG4771	TonB-dependent receptor
CGC64_RS05365	COG1346	cytolysis
CGC64_RS05370	COG1380	Effector of murein hydrolase LrgA
CGC64_RS05375	COG0280	phosphate acetyltransferase
CGC64_RS05380	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CGC64_RS05385	COG1216	Glycosyl transferase, family 2
CGC64_RS05385	COG0463	Glycosyl transferase, family 2
CGC64_RS05390	COG2003	Belongs to the UPF0758 family
CGC64_RS05400	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CGC64_RS05405	COG1785	Belongs to the alkaline phosphatase family
CGC64_RS05410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CGC64_RS05415	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CGC64_RS05425	COG2815	serine threonine protein kinase
CGC64_RS05425	COG0515	serine threonine protein kinase
CGC64_RS05430	COG0564	pseudouridine synthase activity
CGC64_RS05460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CGC64_RS05465	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CGC64_RS05470	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CGC64_RS05480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CGC64_RS05495	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CGC64_RS05500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CGC64_RS05510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGC64_RS05510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CGC64_RS05515	COG2890	protein-(glutamine-N5) methyltransferase activity
CGC64_RS05525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CGC64_RS05535	COG0165	Argininosuccinate lyase
CGC64_RS05590	COG0582	viral genome integration into host DNA
CGC64_RS05660	COG5492	domain, Protein
CGC64_RS05670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CGC64_RS05675	COG1917	Cupin 2, conserved barrel domain protein
CGC64_RS05675	COG1396	sequence-specific DNA binding
CGC64_RS05680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CGC64_RS05685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CGC64_RS05690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CGC64_RS05695	COG0137	argininosuccinate synthase activity
CGC64_RS05705	COG1438	arginine binding
CGC64_RS05710	COG1070	Carbohydrate kinase
CGC64_RS05715	COG4806	L-rhamnose isomerase
CGC64_RS05725	COG0235	Class ii aldolase
CGC64_RS05730	COG1454	alcohol dehydrogenase
CGC64_RS05755	COG0564	pseudouridine synthase activity
CGC64_RS05770	COG3119	arylsulfatase activity
CGC64_RS05790	COG0612	Peptidase, M16
CGC64_RS05795	COG0534	Mate efflux family protein
CGC64_RS05800	COG2205	protein histidine kinase activity
CGC64_RS05800	COG0784	Response regulator, receiver
CGC64_RS05820	COG0488	(ABC) transporter
CGC64_RS05825	COG3590	peptidase
CGC64_RS05830	COG0138	bifunctional purine biosynthesis protein purh
CGC64_RS05855	COG0772	Belongs to the SEDS family
CGC64_RS05865	COG1774	PSP1 C-terminal conserved region
CGC64_RS05870	COG0470	DNA polymerase III
CGC64_RS05875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CGC64_RS05935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGC64_RS05940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CGC64_RS05945	COG1160	GTP binding
CGC64_RS05955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CGC64_RS05960	COG1127	ABC transporter
CGC64_RS05965	COG0724	RNA recognition motif
CGC64_RS05975	COG0544	peptidyl-prolyl cis-trans isomerase activity
CGC64_RS05980	COG0740	serine-type endopeptidase activity
CGC64_RS05985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CGC64_RS05990	COG0514	ATP-dependent DNA helicase (RecQ)
CGC64_RS05995	COG0517	IMP dehydrogenase activity
CGC64_RS05995	COG0516	GMP reductase activity
CGC64_RS06000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC64_RS06010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC64_RS06025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CGC64_RS06070	COG3022	response to hydroperoxide
CGC64_RS06075	COG0110	maltose O-acetyltransferase activity
CGC64_RS06095	COG1187	pseudouridine synthase activity
CGC64_RS06100	COG0017	Asparaginyl-tRNA synthetase
CGC64_RS06115	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CGC64_RS06120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CGC64_RS06125	COG0052	Belongs to the universal ribosomal protein uS2 family
CGC64_RS06130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CGC64_RS06145	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CGC64_RS06150	COG0179	Fumarylacetoacetate (FAA) hydrolase
CGC64_RS06155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CGC64_RS06175	COG0482	sulfurtransferase activity
CGC64_RS06185	COG1570	exodeoxyribonuclease VII activity
CGC64_RS06195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGC64_RS06205	COG0489	protein tyrosine kinase activity
CGC64_RS06210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS06245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS06270	COG0039	L-malate dehydrogenase activity
CGC64_RS06285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CGC64_RS06290	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CGC64_RS06295	COG0811	peptide transport
CGC64_RS06315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CGC64_RS06320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CGC64_RS06325	COG0105	UTP biosynthetic process
CGC64_RS06330	COG0739	heme binding
CGC64_RS06345	COG0149	triose-phosphate isomerase activity
CGC64_RS06355	COG0302	gtp cyclohydrolase
CGC64_RS06360	COG0358	DNA primase activity
CGC64_RS06370	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CGC64_RS06375	COG0436	Aminotransferase
CGC64_RS06395	COG0514	ATP-dependent DNA helicase (RecQ)
CGC64_RS06400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CGC64_RS06400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CGC64_RS06410	COG0009	L-threonylcarbamoyladenylate synthase
CGC64_RS06420	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CGC64_RS06425	COG4974	Belongs to the 'phage' integrase family
CGC64_RS06480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CGC64_RS06485	COG0658	competence protein
CGC64_RS06485	COG2333	competence protein COMEC
CGC64_RS06490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CGC64_RS06500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGC64_RS06505	COG4771	TonB-dependent receptor
CGC64_RS06520	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CGC64_RS06525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CGC64_RS06540	COG0460	homoserine dehydrogenase
CGC64_RS06540	COG0527	aspartate kinase activity
CGC64_RS06545	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
CGC64_RS06585	COG1522	sequence-specific DNA binding
CGC64_RS06600	COG0251	oxidation-reduction process
CGC64_RS06610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CGC64_RS06615	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC64_RS06615	COG1333	cytochrome c biogenesis protein
CGC64_RS06625	COG0110	maltose O-acetyltransferase activity
CGC64_RS06630	COG0386	Belongs to the glutathione peroxidase family
CGC64_RS06635	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CGC64_RS06640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CGC64_RS06695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CGC64_RS06710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGC64_RS06715	COG0742	ribosomal rna small subunit methyltransferase
CGC64_RS06730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGC64_RS06740	COG4771	TonB-dependent receptor
CGC64_RS06750	COG3537	Alpha-1,2-mannosidase
CGC64_RS06755	COG3537	Alpha-1,2-mannosidase
CGC64_RS06775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGC64_RS06780	COG0739	heme binding
CGC64_RS06790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGC64_RS06795	COG1388	LysM domain
CGC64_RS06795	COG0741	lytic transglycosylase activity
CGC64_RS06805	COG1475	DNA binding
CGC64_RS06810	COG1192	Involved in chromosome partitioning
CGC64_RS06815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CGC64_RS06820	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CGC64_RS06835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CGC64_RS06850	COG1196	nuclear chromosome segregation
CGC64_RS06855	COG2239	Acts as a magnesium transporter
CGC64_RS06860	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CGC64_RS06870	COG2195	Cleaves the N-terminal amino acid of tripeptides
CGC64_RS06890	COG3250	beta-galactosidase activity
CGC64_RS06915	COG0668	transmembrane transport
CGC64_RS06920	COG2207	Transcriptional regulator
CGC64_RS06920	COG0662	Cupin 2, conserved barrel domain protein
CGC64_RS06935	COG0784	Response regulator, receiver
CGC64_RS06935	COG2205	protein histidine kinase activity
CGC64_RS06950	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CGC64_RS06955	COG0713	ATP synthesis coupled electron transport
CGC64_RS06970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CGC64_RS06975	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC64_RS06975	COG0649	NAD binding
CGC64_RS06980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC64_RS06985	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CGC64_RS06995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGC64_RS07000	COG0569	domain protein
CGC64_RS07005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGC64_RS07015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CGC64_RS07020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CGC64_RS07025	COG0805	protein transport
CGC64_RS07035	COG2271	Major facilitator Superfamily
CGC64_RS07040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CGC64_RS07045	COG3775	system Galactitol-specific IIC component
CGC64_RS07050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS07060	COG2755	lipolytic protein G-D-S-L family
CGC64_RS07065	COG0745	RESPONSE REGULATOR receiver
CGC64_RS07065	COG3292	Two component regulator propeller
CGC64_RS07065	COG2205	protein histidine kinase activity
CGC64_RS07075	COG0702	epimerase
CGC64_RS07080	COG4771	TonB-dependent receptor
CGC64_RS07100	COG3279	Response regulator of the LytR AlgR family
CGC64_RS07105	COG1242	4 iron, 4 sulfur cluster binding
CGC64_RS07115	COG0363	glucosamine-6-phosphate deaminase activity
CGC64_RS07125	COG0009	L-threonylcarbamoyladenylate synthase
CGC64_RS07135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGC64_RS07140	COG0561	phosphatase activity
CGC64_RS07160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CGC64_RS07175	COG1629	transport
CGC64_RS07175	COG4206	TonB-dependent receptor
CGC64_RS07195	COG3507	Belongs to the glycosyl hydrolase 43 family
CGC64_RS07210	COG3250	beta-galactosidase activity
CGC64_RS07225	COG0546	phosphoglycolate phosphatase activity
CGC64_RS07245	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CGC64_RS07255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CGC64_RS07265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CGC64_RS07305	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGC64_RS07320	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CGC64_RS07320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CGC64_RS07325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CGC64_RS07330	COG1078	dGTPase activity
CGC64_RS07335	COG0284	orotidine-5'-phosphate decarboxylase activity
CGC64_RS07340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CGC64_RS07350	COG1704	LemA family
CGC64_RS07365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CGC64_RS07370	COG2226	methyltransferase
CGC64_RS07375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CGC64_RS07380	COG1702	phosphate starvation-inducible protein PhoH
CGC64_RS07395	COG2268	Band 7 protein
CGC64_RS07440	COG3292	Two component regulator propeller
CGC64_RS07440	COG2205	protein histidine kinase activity
CGC64_RS07440	COG0745	RESPONSE REGULATOR receiver
CGC64_RS07445	COG0101	tRNA pseudouridine synthase activity
CGC64_RS07465	COG3250	beta-galactosidase activity
CGC64_RS07470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CGC64_RS07475	COG0673	inositol 2-dehydrogenase activity
CGC64_RS07500	COG1629	transport
CGC64_RS07515	COG4771	TonB-dependent receptor
CGC64_RS07520	COG0702	epimerase
CGC64_RS07545	COG5434	Belongs to the glycosyl hydrolase 28 family
CGC64_RS07560	COG1629	transport
CGC64_RS07565	COG0561	phosphatase activity
CGC64_RS07585	COG0673	inositol 2-dehydrogenase activity
CGC64_RS07600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CGC64_RS07610	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CGC64_RS07625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CGC64_RS07630	COG0793	Belongs to the peptidase S41A family
CGC64_RS07635	COG2131	deaminase
CGC64_RS07645	COG0339	signal peptide processing
CGC64_RS07655	COG1970	mechanosensitive ion channel activity
CGC64_RS07675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CGC64_RS07675	COG0519	Catalyzes the synthesis of GMP from XMP
CGC64_RS07690	COG4771	TonB-dependent receptor
CGC64_RS07695	COG0561	phosphatase activity
CGC64_RS07700	COG1629	transport
CGC64_RS07730	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS07745	COG0297	glycogen (starch) synthase activity
CGC64_RS07750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CGC64_RS07755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CGC64_RS07760	COG0543	2 iron, 2 sulfur cluster binding
CGC64_RS07770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CGC64_RS07780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CGC64_RS07785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CGC64_RS07800	COG0791	NLP P60 protein
CGC64_RS07815	COG0612	Peptidase, M16
CGC64_RS07820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CGC64_RS07825	COG1597	lipid kinase activity
CGC64_RS07830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CGC64_RS07840	COG0702	epimerase
CGC64_RS07845	COG4771	TonB-dependent receptor
CGC64_RS07860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS07865	COG0745	RESPONSE REGULATOR receiver
CGC64_RS07865	COG3292	Two component regulator propeller
CGC64_RS07865	COG2205	protein histidine kinase activity
CGC64_RS07880	COG1136	(ABC) transporter
CGC64_RS07900	COG2211	Major facilitator Superfamily
CGC64_RS07910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CGC64_RS07925	COG1674	ftsk spoiiie
CGC64_RS07935	COG0492	ferredoxin-NADP+ reductase activity
CGC64_RS07940	COG3118	belongs to the thioredoxin family
CGC64_RS07950	COG1404	Belongs to the peptidase S8 family
CGC64_RS07970	COG4206	TonB-dependent receptor
CGC64_RS07970	COG1629	transport
CGC64_RS08005	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CGC64_RS08005	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CGC64_RS08010	COG0539	negative regulation of cytoplasmic translation
CGC64_RS08015	COG1234	tRNA 3'-trailer cleavage
CGC64_RS08020	COG2989	Protein conserved in bacteria
CGC64_RS08040	COG3956	TIGRFAM MazG family protein
CGC64_RS08060	COG0525	valine-tRNA ligase activity
CGC64_RS08065	COG0784	Response regulator, receiver
CGC64_RS08065	COG2205	protein histidine kinase activity
CGC64_RS08080	COG1629	transport
CGC64_RS08125	COG0653	protein targeting
CGC64_RS08130	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
CGC64_RS08140	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CGC64_RS08160	COG1253	flavin adenine dinucleotide binding
CGC64_RS08165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CGC64_RS08170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CGC64_RS08180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CGC64_RS08225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CGC64_RS08225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CGC64_RS08235	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CGC64_RS08240	COG0563	adenylate kinase activity
CGC64_RS08245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CGC64_RS08250	COG1496	oxidoreductase activity
CGC64_RS08270	COG4206	TonB-dependent receptor
CGC64_RS08270	COG1629	transport
CGC64_RS08275	COG0561	phosphatase activity
CGC64_RS08280	COG3119	arylsulfatase activity
CGC64_RS08295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS08315	COG2814	Major facilitator Superfamily
CGC64_RS08320	COG0457	Tetratricopeptide repeat
CGC64_RS08325	COG2706	6-phosphogluconolactonase activity
CGC64_RS08330	COG4771	TonB-dependent receptor
CGC64_RS08335	COG0702	epimerase
CGC64_RS08340	COG1472	Belongs to the glycosyl hydrolase 3 family
CGC64_RS08350	COG3292	Two component regulator propeller
CGC64_RS08350	COG0745	RESPONSE REGULATOR receiver
CGC64_RS08350	COG2205	protein histidine kinase activity
CGC64_RS08350	COG3292	Two component regulator propeller
CGC64_RS08350	COG0745	RESPONSE REGULATOR receiver
CGC64_RS08350	COG2205	protein histidine kinase activity
CGC64_RS08355	COG1629	transport
CGC64_RS08450	COG3142	Participates in the control of copper homeostasis
CGC64_RS08455	COG1418	mRNA catabolic process
CGC64_RS08470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGC64_RS08475	COG2832	Protein of unknown function (DUF454)
CGC64_RS08485	COG0602	queuosine metabolic process
CGC64_RS08490	COG0247	lactate metabolic process
CGC64_RS08495	COG1139	Iron-sulfur cluster binding protein
CGC64_RS08505	COG0351	phosphomethylpyrimidine kinase
CGC64_RS08510	COG4771	TonB-dependent receptor
CGC64_RS08520	COG2304	oxidoreductase activity
CGC64_RS08525	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS08535	COG1393	Belongs to the ArsC family
CGC64_RS08545	COG4771	TonB-dependent receptor
CGC64_RS08560	COG2233	PERMEase
CGC64_RS08565	COG1509	lysine 2,3-aminomutase activity
CGC64_RS08605	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS08615	COG0776	regulation of translation
CGC64_RS08620	COG0305	Participates in initiation and elongation during chromosome replication
CGC64_RS08650	COG3250	beta-galactosidase activity
CGC64_RS08655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CGC64_RS08660	COG0741	lytic transglycosylase activity
CGC64_RS08660	COG1388	LysM domain
CGC64_RS08680	COG0784	Response regulator, receiver
CGC64_RS08680	COG2205	protein histidine kinase activity
CGC64_RS08705	COG0534	Mate efflux family protein
CGC64_RS08715	COG0564	pseudouridine synthase activity
CGC64_RS08745	COG0346	lactoylglutathione lyase activity
CGC64_RS08760	COG1401	restriction endodeoxyribonuclease activity
CGC64_RS08765	COG4268	DNA restriction-modification system
CGC64_RS08785	COG0432	Pfam Uncharacterised protein family UPF0047
CGC64_RS08805	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CGC64_RS08820	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CGC64_RS08840	COG5290	Psort location Cytoplasmic, score
CGC64_RS08875	COG4974	Belongs to the 'phage' integrase family
CGC64_RS08890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CGC64_RS08900	COG2204	response regulator
CGC64_RS08905	COG2910	NAD(P)H-binding
CGC64_RS08915	COG4864	UPF0365 protein
CGC64_RS08930	COG0037	tRNA processing
CGC64_RS08940	COG1477	protein flavinylation
CGC64_RS08945	COG1971	Probably functions as a manganese efflux pump
CGC64_RS08960	COG0463	Glycosyl transferase, family 2
CGC64_RS08985	COG1595	DNA-templated transcription, initiation
CGC64_RS08990	COG0148	phosphopyruvate hydratase activity
CGC64_RS09000	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CGC64_RS09005	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CGC64_RS09010	COG2195	Cleaves the N-terminal amino acid of tripeptides
CGC64_RS09015	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CGC64_RS09020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CGC64_RS09020	COG4651	solute:proton antiporter activity
CGC64_RS09030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CGC64_RS09035	COG0193	aminoacyl-tRNA hydrolase activity
CGC64_RS09040	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CGC64_RS09050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CGC64_RS09055	COG1862	Preprotein translocase
CGC64_RS09065	COG0237	dephospho-CoA kinase activity
CGC64_RS09080	COG0542	response to heat
CGC64_RS09090	COG0583	DNA-binding transcription factor activity
CGC64_RS09100	COG3304	Inner membrane component domain
CGC64_RS09105	COG2855	membrane
CGC64_RS09125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CGC64_RS09130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CGC64_RS09155	COG0443	Heat shock 70 kDa protein
CGC64_RS09160	COG0306	phosphate transporter
CGC64_RS09170	COG0586	Pfam SNARE associated Golgi protein
CGC64_RS09205	COG0038	chloride channel
CGC64_RS09210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CGC64_RS09215	COG2172	sigma factor antagonist activity
CGC64_RS09240	COG1366	Belongs to the anti-sigma-factor antagonist family
CGC64_RS09245	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CGC64_RS09250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CGC64_RS09265	COG3250	beta-galactosidase activity
CGC64_RS09280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CGC64_RS09285	COG4206	TonB-dependent receptor
CGC64_RS09285	COG1629	transport
CGC64_RS09295	COG2205	protein histidine kinase activity
CGC64_RS09295	COG0745	RESPONSE REGULATOR receiver
CGC64_RS09295	COG3292	Two component regulator propeller
CGC64_RS09320	COG1760	l-serine dehydratase
CGC64_RS09325	COG0598	Magnesium transport protein CorA
CGC64_RS09330	COG1193	negative regulation of DNA recombination
CGC64_RS09375	COG0358	DNA primase activity
CGC64_RS09405	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CGC64_RS09425	COG1629	transport
CGC64_RS09430	COG0745	RESPONSE REGULATOR receiver
CGC64_RS09430	COG3292	Two component regulator propeller
CGC64_RS09430	COG2205	protein histidine kinase activity
CGC64_RS09430	COG2205	protein histidine kinase activity
CGC64_RS09430	COG3292	Two component regulator propeller
CGC64_RS09430	COG0745	RESPONSE REGULATOR receiver
CGC64_RS09460	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CGC64_RS09465	COG5002	protein histidine kinase activity
CGC64_RS09475	COG3189	MarR family transcriptional regulator
CGC64_RS09480	COG0561	phosphatase activity
CGC64_RS09485	COG1169	isochorismate synthase
CGC64_RS09490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGC64_RS09495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CGC64_RS09500	COG4948	Mandelate Racemase Muconate Lactonizing
CGC64_RS09515	COG0783	Belongs to the Dps family
CGC64_RS09520	COG0583	DNA-binding transcription factor activity
CGC64_RS09530	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CGC64_RS09550	COG3458	cephalosporin-C deacetylase activity
CGC64_RS09555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CGC64_RS09560	COG1882	Formate acetyltransferase
CGC64_RS09610	COG4804	nuclease activity
CGC64_RS09655	COG1253	flavin adenine dinucleotide binding
CGC64_RS09660	COG0501	Belongs to the peptidase M48B family
CGC64_RS09685	COG0482	sulfurtransferase activity
CGC64_RS09690	COG2197	response regulator
CGC64_RS09700	COG1757	Na H antiporter
CGC64_RS09710	COG2814	Major facilitator Superfamily
CGC64_RS09715	COG4953	penicillin-binding protein 1C
CGC64_RS09720	COG2373	Large extracellular alpha-helical protein
CGC64_RS09725	COG0545	Peptidyl-prolyl cis-trans isomerase
CGC64_RS09765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CGC64_RS09770	COG1410	methionine synthase
CGC64_RS09770	COG0646	methionine synthase
CGC64_RS09775	COG0778	Nitroreductase
CGC64_RS09785	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CGC64_RS09790	COG0572	uridine kinase
CGC64_RS09800	COG4232	protein-disulfide reductase activity
CGC64_RS09805	COG0738	Major facilitator superfamily
CGC64_RS09815	COG1070	Carbohydrate kinase
CGC64_RS09825	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
CGC64_RS09830	COG2188	Transcriptional regulator
CGC64_RS09835	COG0228	four-way junction DNA binding
CGC64_RS09860	COG3275	phosphorelay sensor kinase activity
CGC64_RS09870	COG0784	Response regulator, receiver
CGC64_RS09870	COG2205	protein histidine kinase activity
CGC64_RS09875	COG5002	protein histidine kinase activity
CGC64_RS09885	COG1733	regulation of RNA biosynthetic process
CGC64_RS09910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CGC64_RS09915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CGC64_RS09920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CGC64_RS09925	COG0131	Imidazoleglycerol-phosphate dehydratase
CGC64_RS09945	COG1773	rubredoxin
CGC64_RS09945	COG1592	Rubrerythrin
CGC64_RS09960	COG0702	epimerase
CGC64_RS09965	COG4771	TonB-dependent receptor
CGC64_RS09990	COG3118	belongs to the thioredoxin family
CGC64_RS10005	COG3591	Belongs to the peptidase S1B family
CGC64_RS10010	COG3591	Belongs to the peptidase S1B family
CGC64_RS10015	COG0641	radical SAM
CGC64_RS10030	COG0420	3'-5' exonuclease activity
CGC64_RS10040	COG1408	metallophosphoesterase
CGC64_RS10055	COG1410	methionine synthase
CGC64_RS10055	COG0646	methionine synthase
CGC64_RS10065	COG0463	Glycosyl transferase, family 2
CGC64_RS10070	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CGC64_RS10075	COG1032	radical SAM domain protein
CGC64_RS10095	COG0363	glucosamine-6-phosphate deaminase activity
CGC64_RS10100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGC64_RS10115	COG4974	Belongs to the 'phage' integrase family
CGC64_RS10135	COG1131	(ABC) transporter
CGC64_RS10170	COG1752	Esterase of the alpha-beta hydrolase superfamily
CGC64_RS10195	COG3757	hydrolase, family 25
CGC64_RS10210	COG0508	dehydrogenase complex catalyzes the overall conversion of
CGC64_RS10215	COG0022	dehydrogenase e1 component
CGC64_RS10225	COG2264	protein methyltransferase activity
CGC64_RS10250	COG0590	tRNA wobble adenosine to inosine editing
CGC64_RS10255	COG0673	inositol 2-dehydrogenase activity
CGC64_RS10260	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CGC64_RS10305	COG0698	ribose 5-phosphate isomerase
CGC64_RS10325	COG2160	L-arabinose isomerase activity
CGC64_RS10355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CGC64_RS10370	COG1482	cell wall glycoprotein biosynthetic process
CGC64_RS10390	COG4221	oxidoreductase activity
CGC64_RS10400	COG1218	3'(2'),5'-bisphosphate nucleotidase
CGC64_RS10405	COG0471	metal ion transport
CGC64_RS10405	COG3273	potassium ion transport
CGC64_RS10410	COG0529	Catalyzes the synthesis of activated sulfate
CGC64_RS10415	COG0175	sulfate reduction
CGC64_RS10420	COG2895	sulfate adenylyltransferase (ATP) activity
CGC64_RS10440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CGC64_RS10445	COG0242	peptide deformylase activity
CGC64_RS10455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CGC64_RS10460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CGC64_RS10465	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CGC64_RS10470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CGC64_RS10480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CGC64_RS10485	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CGC64_RS10490	COG0674	pyruvate-flavodoxin oxidoreductase activity
CGC64_RS10490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CGC64_RS10490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CGC64_RS10490	COG1013	pyruvate-flavodoxin oxidoreductase activity
CGC64_RS10500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CGC64_RS10525	COG2197	response regulator
CGC64_RS10720	COG0863	Belongs to the N(4) N(6)-methyltransferase family
CGC64_RS11125	COG1940	carbohydrate kinase activity
CGC64_RS11130	COG2731	YhcH YjgK YiaL family protein
CGC64_RS11135	COG2271	Major facilitator Superfamily
CGC64_RS11140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGC64_RS11150	COG4771	TonB-dependent receptor
CGC64_RS11155	COG0702	epimerase
CGC64_RS11165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS11185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS11190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS11195	COG4771	TonB-dependent receptor
CGC64_RS11200	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CGC64_RS11205	COG0484	heat shock protein binding
CGC64_RS11210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CGC64_RS11215	COG0488	(ABC) transporter
CGC64_RS11230	COG2183	response to ionizing radiation
CGC64_RS11235	COG2202	Pas domain
CGC64_RS11235	COG2205	protein histidine kinase activity
CGC64_RS11240	COG0737	Belongs to the 5'-nucleotidase family
CGC64_RS11280	COG0490	domain, Protein
CGC64_RS11280	COG2985	domain, Protein
CGC64_RS11285	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CGC64_RS11295	COG0318	PFAM AMP-dependent synthetase and ligase
CGC64_RS11300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC64_RS11305	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CGC64_RS11310	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CGC64_RS11315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CGC64_RS11320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CGC64_RS11325	COG0363	glucosamine-6-phosphate deaminase activity
CGC64_RS11340	COG3279	Response regulator of the LytR AlgR family
CGC64_RS11350	COG0577	efflux transmembrane transporter activity
CGC64_RS11350	COG1136	(ABC) transporter
CGC64_RS11355	COG1136	(ABC) transporter
CGC64_RS11360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS11385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGC64_RS11390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CGC64_RS11420	COG1704	LemA family
CGC64_RS11430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGC64_RS11435	COG2885	chlorophyll binding
CGC64_RS11440	COG0534	Mate efflux family protein
CGC64_RS11450	COG0784	Response regulator, receiver
CGC64_RS11450	COG2205	protein histidine kinase activity
CGC64_RS11465	COG0488	(ABC) transporter
CGC64_RS11480	COG2205	protein histidine kinase activity
CGC64_RS11480	COG0784	Response regulator, receiver
CGC64_RS11510	COG2244	polysaccharide biosynthetic process
CGC64_RS11515	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS11545	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS11590	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CGC64_RS11595	COG1805	sodium ion transport
CGC64_RS11600	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CGC64_RS11615	COG2871	sodium ion transport
CGC64_RS11625	COG0513	Belongs to the DEAD box helicase family
CGC64_RS11630	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CGC64_RS11635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGC64_RS11645	COG1739	Uncharacterized protein family UPF0029
CGC64_RS11660	COG0778	Nitroreductase
CGC64_RS11665	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGC64_RS11665	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CGC64_RS11670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CGC64_RS11675	COG0357	Ribosomal RNA small subunit methyltransferase G
CGC64_RS11690	COG1629	transport
CGC64_RS11690	COG4206	TonB-dependent receptor
CGC64_RS11700	COG2217	Heavy metal translocating P-type atpase
CGC64_RS11710	COG0321	lipoyl(octanoyl) transferase activity
CGC64_RS11740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CGC64_RS11750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CGC64_RS11765	COG1678	Uncharacterized ACR, COG1678
CGC64_RS11780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CGC64_RS11785	COG0662	Cupin 2, conserved barrel domain protein
CGC64_RS11785	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CGC64_RS11805	COG1131	(ABC) transporter
CGC64_RS11810	COG0842	Transport permease protein
CGC64_RS11815	COG0842	Transport permease protein
CGC64_RS11820	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CGC64_RS11825	COG2949	membrane
CGC64_RS11830	COG0556	nucleotide-excision repair
CGC64_RS11835	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CGC64_RS11865	COG3942	CHAP domain
CGC64_RS11865	COG1388	LysM domain
CGC64_RS11875	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CGC64_RS11890	COG1695	Transcriptional regulator
CGC64_RS11910	COG0823	Involved in the tonB-independent uptake of proteins
CGC64_RS11910	COG1506	peptidase
CGC64_RS11915	COG0534	Mate efflux family protein
CGC64_RS11920	COG0706	membrane insertase activity
CGC64_RS11925	COG0504	CTP synthase activity
CGC64_RS12015	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS12035	COG1442	glycosyl transferase family 8
CGC64_RS12035	COG1216	Glycosyl transferase, family 2
CGC64_RS12045	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS12055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGC64_RS12095	COG4656	Part of a membrane complex involved in electron transport
CGC64_RS12100	COG4658	electron transport chain
CGC64_RS12105	COG4659	FMN binding
CGC64_RS12110	COG4660	Part of a membrane complex involved in electron transport
CGC64_RS12115	COG4657	Part of a membrane complex involved in electron transport
CGC64_RS12120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CGC64_RS12130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CGC64_RS12135	COG0305	Participates in initiation and elongation during chromosome replication
CGC64_RS12140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CGC64_RS12140	COG0072	phenylalanine-tRNA ligase activity
CGC64_RS12145	COG0217	transcriptional regulatory protein
CGC64_RS12160	COG0708	Exodeoxyribonuclease III
CGC64_RS12175	COG0481	GTPase activity
CGC64_RS12200	COG0024	Methionine aminopeptidase
CGC64_RS12220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CGC64_RS12230	COG0574	Belongs to the PEP-utilizing enzyme family
CGC64_RS12230	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CGC64_RS12250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CGC64_RS12260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CGC64_RS12265	COG2022	thiamine diphosphate biosynthetic process
CGC64_RS12270	COG0352	thiamine-phosphate diphosphorylase activity
CGC64_RS12280	COG3850	Histidine kinase
CGC64_RS12280	COG4999	Histidine kinase
CGC64_RS12280	COG3437	response regulator, receiver
CGC64_RS12280	COG2205	protein histidine kinase activity
CGC64_RS12295	COG0210	DNA helicase
CGC64_RS12380	COG0681	Belongs to the peptidase S26 family
CGC64_RS12395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS12470	COG1082	Xylose isomerase domain protein TIM barrel
CGC64_RS12475	COG1022	Amp-dependent synthetase and ligase
CGC64_RS12480	COG3263	regulation of cellular component size
CGC64_RS12485	COG2233	PERMEase
CGC64_RS12490	COG1151	hydroxylamine reductase activity
CGC64_RS12515	COG0561	phosphatase activity
CGC64_RS12535	COG0577	efflux transmembrane transporter activity
CGC64_RS12535	COG1136	(ABC) transporter
CGC64_RS12545	COG0534	Mate efflux family protein
CGC64_RS12550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC64_RS12555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CGC64_RS12565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CGC64_RS12585	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CGC64_RS12590	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CGC64_RS12595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CGC64_RS12605	COG0356	it plays a direct role in the translocation of protons across the membrane
CGC64_RS12610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGC64_RS12615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CGC64_RS12620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGC64_RS12625	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CGC64_RS12630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CGC64_RS12635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CGC64_RS12640	COG2431	L-lysine efflux transmembrane transporter activity
CGC64_RS12660	COG2207	Transcriptional regulator
CGC64_RS12660	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CGC64_RS12685	COG2985	domain, Protein
CGC64_RS12690	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CGC64_RS12695	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CGC64_RS12710	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CGC64_RS12715	COG0540	Belongs to the ATCase OTCase family
CGC64_RS12970	COG4974	Belongs to the 'phage' integrase family
CGC64_RS13025	COG1216	Glycosyl transferase, family 2
CGC64_RS13065	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS13075	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS13080	COG0438	transferase activity, transferring glycosyl groups
CGC64_RS13110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGC64_RS13120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CGC64_RS13130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CGC64_RS13145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CGC64_RS13150	COG2205	protein histidine kinase activity
CGC64_RS13185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CGC64_RS13200	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CGC64_RS13220	COG0348	domain, Protein
CGC64_RS13225	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CGC64_RS13240	COG2326	polyphosphate kinase activity
CGC64_RS13270	COG0724	RNA recognition motif
CGC64_RS13275	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CGC64_RS13280	COG0045	succinate-CoA ligase (ADP-forming) activity
CGC64_RS13285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CGC64_RS13290	COG0351	phosphomethylpyrimidine kinase
CGC64_RS13305	COG2115	Belongs to the xylose isomerase family
CGC64_RS13310	COG2814	Major facilitator Superfamily
CGC64_RS13310	COG0477	Major facilitator Superfamily
CGC64_RS13315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CGC64_RS13315	COG3153	acetyltransferase
CGC64_RS13325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CGC64_RS13335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CGC64_RS13350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGC64_RS13375	COG3015	lipoprotein NlpE involved in copper resistance
CGC64_RS13395	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CGC64_RS13410	COG1904	glucuronate isomerase
CGC64_RS13420	COG0246	Mannitol dehydrogenase
CGC64_RS13450	COG0513	Belongs to the DEAD box helicase family
CGC64_RS13455	COG0560	Phosphoserine phosphatase
CGC64_RS13455	COG3830	Belongs to the UPF0237 family
CGC64_RS13480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CGC64_RS13485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CGC64_RS13545	COG1136	(ABC) transporter
CGC64_RS13545	COG0577	efflux transmembrane transporter activity
CGC64_RS13575	COG0156	8-amino-7-oxononanoate synthase activity
CGC64_RS13580	COG1597	lipid kinase activity
CGC64_RS13585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CGC64_RS13600	COG2957	Belongs to the agmatine deiminase family
CGC64_RS13630	COG4771	TonB-dependent receptor
CGC64_RS13635	COG0702	epimerase
CGC64_RS13660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CGC64_RS13670	COG1538	Outer membrane efflux protein
CGC64_RS13690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CGC64_RS13705	COG0543	2 iron, 2 sulfur cluster binding
CGC64_RS13710	COG0167	dihydroorotate dehydrogenase activity
CGC64_RS13715	COG0336	Belongs to the RNA methyltransferase TrmD family
CGC64_RS13720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CGC64_RS13725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGC64_RS13750	COG1752	Esterase of the alpha-beta hydrolase superfamily
CGC64_RS13755	COG0326	Molecular chaperone. Has ATPase activity
CGC64_RS13760	COG0542	response to heat
CGC64_RS13765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CGC64_RS13805	COG2304	oxidoreductase activity
CGC64_RS13820	COG0714	Associated with various cellular activities
CGC64_RS13830	COG0776	regulation of translation
CGC64_RS13835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CGC64_RS13840	COG0552	protein localization to endoplasmic reticulum
CGC64_RS13850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CGC64_RS13855	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CGC64_RS13865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CGC64_RS13900	COG5002	protein histidine kinase activity
CGC64_RS13905	COG0745	RESPONSE REGULATOR receiver
CGC64_RS13910	COG0442	prolyl-tRNA aminoacylation
CGC64_RS13925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS13940	COG3292	Two component regulator propeller
CGC64_RS13940	COG0745	RESPONSE REGULATOR receiver
CGC64_RS13940	COG2205	protein histidine kinase activity
CGC64_RS13950	COG4771	TonB-dependent receptor
CGC64_RS13970	COG0738	Major facilitator superfamily
CGC64_RS13990	COG1011	Hydrolase
CGC64_RS13995	COG0300	oxidoreductase activity
CGC64_RS14010	COG2966	Psort location CytoplasmicMembrane, score
CGC64_RS14025	COG3250	beta-galactosidase activity
CGC64_RS14030	COG0784	Response regulator, receiver
CGC64_RS14030	COG2205	protein histidine kinase activity
CGC64_RS14075	COG1028	Short-chain dehydrogenase reductase Sdr
CGC64_RS14085	COG3537	Alpha-1,2-mannosidase
CGC64_RS14090	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CGC64_RS14100	COG1074	ATP-dependent DNA helicase activity
CGC64_RS14130	COG1475	DNA binding
CGC64_RS14135	COG3969	phosphoadenosine phosphosulfate
CGC64_RS14155	COG0305	Participates in initiation and elongation during chromosome replication
CGC64_RS14170	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS14185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGC64_RS14225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CGC64_RS14240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGC64_RS14275	COG0505	Belongs to the CarA family
CGC64_RS14285	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CGC64_RS14290	COG0070	glutamate synthase
CGC64_RS14290	COG0067	glutamate synthase
CGC64_RS14290	COG0069	glutamate synthase activity
CGC64_RS14300	COG0367	asparagine synthase
CGC64_RS14320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CGC64_RS14325	COG0436	Aminotransferase
CGC64_RS14340	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGC64_RS14355	COG0490	domain, Protein
CGC64_RS14355	COG0471	metal ion transport
CGC64_RS14360	COG1979	alcohol dehydrogenase
CGC64_RS14370	COG0133	tryptophan synthase activity
CGC64_RS14375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CGC64_RS14385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CGC64_RS14390	COG0134	indole-3-glycerol-phosphate synthase activity
CGC64_RS14395	COG0135	phosphoribosylanthranilate isomerase activity
CGC64_RS14400	COG0159	tryptophan synthase activity
CGC64_RS14405	COG0252	asparaginase activity
CGC64_RS14415	COG0745	RESPONSE REGULATOR receiver
CGC64_RS14435	COG2197	response regulator
CGC64_RS14445	COG0138	bifunctional purine biosynthesis protein purh
CGC64_RS14455	COG0716	FMN binding
CGC64_RS14475	COG4771	TonB-dependent receptor
CGC64_RS14485	COG4771	TonB-dependent receptor
CGC64_RS14495	COG0490	domain, Protein
CGC64_RS14495	COG2985	domain, Protein
CGC64_RS14515	COG4771	TonB-dependent receptor
CGC64_RS14555	COG1609	Transcriptional regulator
CGC64_RS14560	COG2721	sulfolactate sulfo-lyase activity
CGC64_RS14605	COG2207	Transcriptional regulator
CGC64_RS14620	COG1177	transmembrane transport
CGC64_RS14625	COG1176	ABC-type spermidine putrescine transport system, permease component I
CGC64_RS14630	COG3842	ATPase activity
CGC64_RS14635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CGC64_RS14645	COG0058	SHG alpha-glucan phosphorylase activity
CGC64_RS14655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CGC64_RS14675	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CGC64_RS14735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CGC64_RS14740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CGC64_RS14745	COG4948	Mandelate Racemase Muconate Lactonizing
CGC64_RS14760	COG1295	ribonuclease BN
CGC64_RS14765	COG1506	peptidase
CGC64_RS14765	COG4946	Tricorn protease homolog
CGC64_RS14765	COG0823	Involved in the tonB-independent uptake of proteins
CGC64_RS14770	COG0778	Nitroreductase
CGC64_RS14780	COG0704	Plays a role in the regulation of phosphate uptake
CGC64_RS14785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CGC64_RS14790	COG0581	inorganic phosphate transmembrane transporter activity
CGC64_RS14795	COG0573	inorganic phosphate transmembrane transporter activity
CGC64_RS14825	COG1629	transport
CGC64_RS14825	COG4206	TonB-dependent receptor
CGC64_RS14835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CGC64_RS14845	COG0586	Pfam SNARE associated Golgi protein
CGC64_RS14855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CGC64_RS14870	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CGC64_RS14875	COG0167	dihydroorotate dehydrogenase activity
CGC64_RS14880	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CGC64_RS14915	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS14920	COG2433	Pfam Transposase IS66
CGC64_RS14950	COG1215	transferase activity, transferring glycosyl groups
CGC64_RS14975	COG1216	Glycosyl transferase, family 2
CGC64_RS14980	COG1216	Glycosyl transferase, family 2
CGC64_RS14985	COG5039	Polysaccharide pyruvyl transferase
CGC64_RS15035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CGC64_RS15040	COG0497	DNA recombination
CGC64_RS15055	COG0592	DNA-directed DNA polymerase activity
CGC64_RS15070	COG0321	lipoyl(octanoyl) transferase activity
CGC64_RS15070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CGC64_RS15075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CGC64_RS15085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC64_RS15090	COG0156	8-amino-7-oxononanoate synthase activity
CGC64_RS15105	COG0019	diaminopimelate decarboxylase activity
CGC64_RS15110	COG0527	aspartate kinase activity
CGC64_RS15115	COG2884	Cell division ATP-binding protein ftsE
CGC64_RS15120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CGC64_RS15120	COG0140	phosphoribosyl-ATP diphosphatase activity
CGC64_RS15125	COG0107	imidazoleglycerol-phosphate synthase activity
CGC64_RS15130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CGC64_RS15135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CGC64_RS15140	COG0788	formyltetrahydrofolate deformylase activity
CGC64_RS15155	COG0693	protein deglycase activity
CGC64_RS15170	COG0534	Mate efflux family protein
CGC64_RS15175	COG2076	Multidrug Resistance protein
CGC64_RS15190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CGC64_RS15205	COG4884	unkown
CGC64_RS15205	COG3831	ATPase activity
CGC64_RS15210	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CGC64_RS15210	COG2885	chlorophyll binding
CGC64_RS15250	COG3546	catalase activity
CGC64_RS15275	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CGC64_RS15290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CGC64_RS15295	COG4946	Tricorn protease homolog
CGC64_RS15295	COG1506	peptidase
CGC64_RS15295	COG0823	Involved in the tonB-independent uptake of proteins
CGC64_RS15305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CGC64_RS15310	COG0778	Nitroreductase
CGC64_RS15335	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CGC64_RS15340	COG4804	nuclease activity
CGC64_RS15345	COG0732	type I restriction modification DNA specificity domain
CGC64_RS15360	COG0732	type I restriction modification DNA specificity domain
CGC64_RS15395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC64_RS15405	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CGC64_RS15420	COG4771	TonB-dependent receptor
CGC64_RS15465	COG1312	Catalyzes the dehydration of D-mannonate
CGC64_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
CGC64_RS15475	COG1609	Transcriptional regulator
CGC64_RS15490	COG2223	nitrite transmembrane transporter activity
CGC64_RS15500	COG4771	TonB-dependent receptor
CGC64_RS15510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CGC64_RS15510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CGC64_RS15525	COG2226	methyltransferase
CGC64_RS15535	COG0511	ligase activity, forming carbon-carbon bonds
CGC64_RS15540	COG0439	Biotin carboxylase
CGC64_RS15545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGC64_RS15560	COG1620	l-lactate permease
CGC64_RS15570	COG0456	acetyltransferase
CGC64_RS15605	COG4771	TonB-dependent receptor
CGC64_RS15625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CGC64_RS15645	COG0577	efflux transmembrane transporter activity
CGC64_RS15645	COG1136	(ABC) transporter
CGC64_RS15650	COG1136	(ABC) transporter
CGC64_RS15650	COG0577	efflux transmembrane transporter activity
CGC64_RS15660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS15675	COG3852	Histidine kinase
CGC64_RS15680	COG0628	permease
CGC64_RS15685	COG1215	transferase activity, transferring glycosyl groups
CGC64_RS15690	COG0577	efflux transmembrane transporter activity
CGC64_RS15690	COG1136	(ABC) transporter
CGC64_RS15695	COG0436	Aminotransferase
CGC64_RS15715	COG0488	(ABC) transporter
CGC64_RS15730	COG0745	RESPONSE REGULATOR receiver
CGC64_RS15735	COG5002	protein histidine kinase activity
CGC64_RS15770	COG0629	single-stranded DNA binding
CGC64_RS15775	COG1194	a g-specific adenine glycosylase
CGC64_RS15785	COG1530	ribonuclease E activity
CGC64_RS15830	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS15860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CGC64_RS15870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CGC64_RS15885	COG4191	Histidine kinase
CGC64_RS15890	COG2204	response regulator
CGC64_RS15905	COG1136	(ABC) transporter
CGC64_RS15925	COG1252	NADH dehydrogenase
CGC64_RS15930	COG1705	Flagellar rod assembly protein muramidase FlgJ
CGC64_RS15935	COG0295	cytidine deaminase activity
CGC64_RS15945	COG3059	membrane
CGC64_RS15950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CGC64_RS15955	COG0488	(ABC) transporter
CGC64_RS15980	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CGC64_RS16015	COG4206	TonB-dependent receptor
CGC64_RS16015	COG1629	transport
CGC64_RS16070	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CGC64_RS16075	COG1629	transport
CGC64_RS16095	COG3250	beta-galactosidase activity
CGC64_RS16100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CGC64_RS16105	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CGC64_RS16115	COG1595	DNA-templated transcription, initiation
CGC64_RS16130	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CGC64_RS16135	COG1741	Belongs to the pirin family
CGC64_RS16140	COG0259	pyridoxamine-phosphate oxidase activity
CGC64_RS16155	COG0346	lactoylglutathione lyase activity
CGC64_RS16220	COG1918	ferrous iron import across plasma membrane
CGC64_RS16220	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CGC64_RS16225	COG0037	tRNA processing
CGC64_RS16240	COG3119	arylsulfatase activity
CGC64_RS16245	COG2202	Pas domain
CGC64_RS16245	COG2205	protein histidine kinase activity
CGC64_RS16250	COG2205	protein histidine kinase activity
CGC64_RS16255	COG0534	Mate efflux family protein
CGC64_RS16260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CGC64_RS16270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CGC64_RS16275	COG1858	cytochrome C peroxidase
CGC64_RS16280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CGC64_RS16295	COG1983	PspC domain protein
CGC64_RS16300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CGC64_RS16325	COG2195	Cleaves the N-terminal amino acid of tripeptides
CGC64_RS16335	COG0668	transmembrane transport
CGC64_RS16345	COG3250	beta-galactosidase activity
CGC64_RS16350	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS16355	COG3119	arylsulfatase activity
CGC64_RS16360	COG0702	epimerase
CGC64_RS16365	COG4206	TonB-dependent receptor
CGC64_RS16365	COG1629	transport
CGC64_RS16375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CGC64_RS16385	COG2205	protein histidine kinase activity
CGC64_RS16385	COG0745	RESPONSE REGULATOR receiver
CGC64_RS16385	COG3292	Two component regulator propeller
CGC64_RS16385	COG3292	Two component regulator propeller
CGC64_RS16385	COG2205	protein histidine kinase activity
CGC64_RS16385	COG0745	RESPONSE REGULATOR receiver
CGC64_RS16390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CGC64_RS16395	COG1830	Aldolase
CGC64_RS16400	COG0588	phosphoglycerate mutase activity
CGC64_RS16410	COG1119	ATPase activity
CGC64_RS16415	COG1523	belongs to the glycosyl hydrolase 13 family
CGC64_RS16420	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CGC64_RS16440	COG1472	Belongs to the glycosyl hydrolase 3 family
CGC64_RS16455	COG3250	beta-galactosidase activity
CGC64_RS16465	COG3408	Glycogen debranching enzyme
CGC64_RS16475	COG4206	TonB-dependent receptor
CGC64_RS16475	COG1629	transport
CGC64_RS16505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS16535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CGC64_RS16550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CGC64_RS16560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CGC64_RS16565	COG2814	Major facilitator Superfamily
CGC64_RS16570	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CGC64_RS16575	COG0126	phosphoglycerate kinase activity
CGC64_RS16590	COG2311	Membrane
CGC64_RS16600	COG0424	maF-like protein
CGC64_RS16620	COG0778	Nitroreductase
CGC64_RS16630	COG0288	reversible hydration of carbon dioxide
CGC64_RS16645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGC64_RS16655	COG0511	ligase activity, forming carbon-carbon bonds
CGC64_RS16660	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CGC64_RS16670	COG0191	fructose-bisphosphate aldolase activity
CGC64_RS16675	COG0254	rRNA binding
CGC64_RS16690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS16705	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CGC64_RS16730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CGC64_RS16745	COG1280	lysine exporter protein (LysE YggA)
CGC64_RS16750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CGC64_RS16750	COG0047	phosphoribosylformylglycinamidine synthase activity
CGC64_RS16755	COG0745	RESPONSE REGULATOR receiver
CGC64_RS16755	COG2205	protein histidine kinase activity
CGC64_RS16755	COG3292	Two component regulator propeller
CGC64_RS16755	COG0745	RESPONSE REGULATOR receiver
CGC64_RS16755	COG2205	protein histidine kinase activity
CGC64_RS16755	COG3292	Two component regulator propeller
CGC64_RS16775	COG1649	PFAM Uncharacterised BCR, COG1649
CGC64_RS16795	COG1966	Carbon starvation protein
CGC64_RS16800	COG1649	PFAM Uncharacterised BCR, COG1649
CGC64_RS16825	COG2113	Glycine betaine
CGC64_RS16830	COG4176	ABC-type proline glycine betaine transport system permease component
CGC64_RS16850	COG2205	protein histidine kinase activity
CGC64_RS16850	COG3292	Two component regulator propeller
CGC64_RS16850	COG0745	RESPONSE REGULATOR receiver
CGC64_RS16855	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CGC64_RS16855	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CGC64_RS16865	COG1621	beta-fructofuranosidase activity
CGC64_RS16885	COG1629	transport
CGC64_RS16890	COG1621	beta-fructofuranosidase activity
CGC64_RS16930	COG3279	Response regulator of the LytR AlgR family
CGC64_RS16950	COG4772	TonB-dependent receptor
CGC64_RS16970	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CGC64_RS16975	COG1960	acyl-CoA dehydrogenase activity
CGC64_RS16995	COG1956	GAF domain-containing protein
CGC64_RS17005	COG0484	heat shock protein binding
CGC64_RS17010	COG2194	sulfuric ester hydrolase activity
CGC64_RS17030	COG0028	Belongs to the TPP enzyme family
CGC64_RS17180	COG0473	3-isopropylmalate dehydrogenase activity
CGC64_RS17185	COG0473	3-isopropylmalate dehydrogenase activity
CGC64_RS17415	COG1629	transport
CGC64_RS17435	COG0745	RESPONSE REGULATOR receiver
CGC64_RS17435	COG2205	protein histidine kinase activity
CGC64_RS17435	COG3292	Two component regulator propeller
CGC64_RS17450	COG0551	DNA topoisomerase type I activity
CGC64_RS17450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CGC64_RS17525	COG0513	Belongs to the DEAD box helicase family
CGC64_RS17530	COG0724	RNA recognition motif
CGC64_RS17580	COG4977	sequence-specific DNA binding
CGC64_RS17580	COG1917	Cupin 2, conserved barrel domain protein
CGC64_RS17595	COG1028	Short-chain dehydrogenase reductase Sdr
CGC64_RS17600	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CGC64_RS17605	COG0456	acetyltransferase
CGC64_RS17620	COG0439	Biotin carboxylase
CGC64_RS17630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CGC64_RS17635	COG2855	membrane
CGC64_RS17640	COG3292	Two component regulator propeller
CGC64_RS17640	COG2205	protein histidine kinase activity
CGC64_RS17640	COG0745	RESPONSE REGULATOR receiver
CGC64_RS17650	COG1629	transport
CGC64_RS17650	COG4206	TonB-dependent receptor
CGC64_RS17695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CGC64_RS17745	COG0024	Methionine aminopeptidase
CGC64_RS17750	COG3119	arylsulfatase activity
CGC64_RS17755	COG3119	arylsulfatase activity
CGC64_RS17760	COG0617	tRNA 3'-terminal CCA addition
CGC64_RS17770	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CGC64_RS17785	COG0632	four-way junction helicase activity
CGC64_RS17790	COG0673	inositol 2-dehydrogenase activity
CGC64_RS17805	COG1272	protein, Hemolysin III
CGC64_RS17810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CGC64_RS17815	COG1328	CTP reductase activity
CGC64_RS17825	COG2814	Major facilitator Superfamily
CGC64_RS17835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CGC64_RS17850	COG0750	zinc metalloprotease
CGC64_RS17855	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CGC64_RS17865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CGC64_RS17870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CGC64_RS17880	COG1214	PFAM Peptidase M22, glycoprotease
CGC64_RS17930	COG0194	GDP metabolic process
CGC64_RS17935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CGC64_RS17940	COG1408	metallophosphoesterase
CGC64_RS17945	COG1575	Belongs to the MenA family. Type 1 subfamily
CGC64_RS17960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CGC64_RS17970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CGC64_RS18015	COG3023	N-Acetylmuramoyl-L-alanine amidase
CGC64_RS18030	COG2204	response regulator
CGC64_RS18035	COG0488	(ABC) transporter
CGC64_RS18050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS18065	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CGC64_RS18065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CGC64_RS18085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CGC64_RS18090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CGC64_RS18100	COG1522	sequence-specific DNA binding
CGC64_RS18135	COG0811	peptide transport
CGC64_RS18145	COG0084	hydrolase, TatD family'
CGC64_RS18165	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CGC64_RS18170	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CGC64_RS18175	COG0205	6-phosphofructokinase activity
CGC64_RS18190	COG4206	TonB-dependent receptor
CGC64_RS18210	COG0372	Belongs to the citrate synthase family
CGC64_RS18215	COG0538	isocitrate dehydrogenase activity
CGC64_RS18220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CGC64_RS18225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CGC64_RS18230	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CGC64_RS18245	COG0028	Belongs to the TPP enzyme family
CGC64_RS18250	COG0129	dihydroxy-acid dehydratase activity
CGC64_RS18260	COG3681	Belongs to the UPF0597 family
CGC64_RS18285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CGC64_RS18315	COG4771	TonB-dependent receptor
CGC64_RS18335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGC64_RS18335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGC64_RS18340	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CGC64_RS18345	COG0569	domain protein
CGC64_RS18345	COG2985	domain, Protein
CGC64_RS18385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CGC64_RS18390	COG1120	ATPase activity
CGC64_RS18410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CGC64_RS18420	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CGC64_RS18425	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CGC64_RS18430	COG0166	Belongs to the GPI family
CGC64_RS18465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CGC64_RS18470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CGC64_RS18490	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CGC64_RS18495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CGC64_RS18520	COG2843	Capsule synthesis protein
CGC64_RS18545	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CGC64_RS18550	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CGC64_RS18560	COG1086	Polysaccharide biosynthesis protein
CGC64_RS18595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CGC64_RS18600	COG4641	Protein conserved in bacteria
CGC64_RS18600	COG1388	LysM domain
CGC64_RS18665	COG2502	aspartate--ammonia ligase
CGC64_RS18670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CGC64_RS18685	COG3876	Protein conserved in bacteria
CGC64_RS18715	COG0860	N-Acetylmuramoyl-L-alanine amidase