locus-tag	class	description
GKD17_RS00005	COG0445	tRNA wobble uridine modification
GKD17_RS00010	COG2268	Band 7 protein
GKD17_RS00020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKD17_RS00040	COG0745	RESPONSE REGULATOR receiver
GKD17_RS00045	COG5002	protein histidine kinase activity
GKD17_RS00050	COG0700	Nucleoside recognition
GKD17_RS00115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKD17_RS00120	COG0793	Belongs to the peptidase S41A family
GKD17_RS00120	COG3409	Peptidoglycan-binding domain 1 protein
GKD17_RS00135	COG1053	succinate dehydrogenase
GKD17_RS00180	COG0758	DNA mediated transformation
GKD17_RS00180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKD17_RS00200	COG1454	alcohol dehydrogenase
GKD17_RS00210	COG0584	glycerophosphoryl diester phosphodiesterase
GKD17_RS00225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GKD17_RS00230	COG0681	Belongs to the peptidase S26 family
GKD17_RS00235	COG0681	Belongs to the peptidase S26 family
GKD17_RS00245	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS00250	COG1312	Catalyzes the dehydration of D-mannonate
GKD17_RS00255	COG4771	TonB-dependent receptor
GKD17_RS00265	COG3119	arylsulfatase activity
GKD17_RS00270	COG2198	Histidine kinase
GKD17_RS00270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS00270	COG0784	Response regulator, receiver
GKD17_RS00270	COG2205	protein histidine kinase activity
GKD17_RS00280	COG0612	Peptidase, M16
GKD17_RS00290	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GKD17_RS00290	COG0517	IMP dehydrogenase activity
GKD17_RS00305	COG0308	aminopeptidase N
GKD17_RS00310	COG0482	sulfurtransferase activity
GKD17_RS00400	COG4974	Belongs to the 'phage' integrase family
GKD17_RS00405	COG2255	four-way junction helicase activity
GKD17_RS00420	COG3591	Belongs to the peptidase S1B family
GKD17_RS00445	COG3655	Transcriptional regulator
GKD17_RS00480	COG0196	riboflavin kinase activity
GKD17_RS00485	COG1011	Hydrolase
GKD17_RS00490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GKD17_RS00580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKD17_RS00655	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GKD17_RS00680	COG2166	iron-sulfur cluster assembly
GKD17_RS00690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GKD17_RS00695	COG0280	phosphate acetyltransferase
GKD17_RS00700	COG3426	butyrate kinase activity
GKD17_RS00715	COG3328	transposase activity
GKD17_RS00730	COG1522	sequence-specific DNA binding
GKD17_RS00740	COG1253	flavin adenine dinucleotide binding
GKD17_RS00765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKD17_RS00770	COG1166	arginine decarboxylase activity
GKD17_RS00775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GKD17_RS00780	COG1595	DNA-templated transcription, initiation
GKD17_RS00800	COG3458	cephalosporin-C deacetylase activity
GKD17_RS00845	COG2814	Major facilitator Superfamily
GKD17_RS00855	COG0779	Required for maturation of 30S ribosomal subunits
GKD17_RS00860	COG0195	Participates in both transcription termination and antitermination
GKD17_RS00865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKD17_RS00875	COG0719	Fe-S assembly protein
GKD17_RS00880	COG0396	ATPase activity
GKD17_RS00885	COG0719	Fe-S assembly protein
GKD17_RS00890	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKD17_RS00900	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GKD17_RS00900	COG3408	Glycogen debranching enzyme
GKD17_RS00905	COG3250	beta-galactosidase activity
GKD17_RS00910	COG2431	L-lysine efflux transmembrane transporter activity
GKD17_RS00920	COG0702	epimerase
GKD17_RS00925	COG4206	TonB-dependent receptor
GKD17_RS00925	COG1629	transport
GKD17_RS00935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKD17_RS00940	COG0738	Major facilitator superfamily
GKD17_RS00945	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
GKD17_RS00955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKD17_RS00985	COG0366	Alpha amylase catalytic
GKD17_RS01000	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS01015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS01020	COG4206	TonB-dependent receptor
GKD17_RS01020	COG1629	transport
GKD17_RS01025	COG1082	Xylose isomerase domain protein TIM barrel
GKD17_RS01030	COG0366	Alpha amylase catalytic
GKD17_RS01065	COG1640	4-alpha-glucanotransferase
GKD17_RS01070	COG0187	DNA topoisomerase II activity
GKD17_RS01075	COG0268	Binds directly to 16S ribosomal RNA
GKD17_RS01085	COG1381	Involved in DNA repair and RecF pathway recombination
GKD17_RS01095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKD17_RS01110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GKD17_RS01115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKD17_RS01120	COG0772	Belongs to the SEDS family
GKD17_RS01125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKD17_RS01130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKD17_RS01135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKD17_RS01140	COG0768	penicillin binding
GKD17_RS01150	COG0275	rRNA processing
GKD17_RS01155	COG2001	Belongs to the MraZ family
GKD17_RS01175	COG0756	dUTP diphosphatase activity
GKD17_RS01180	COG3063	Type IV pilus biogenesis stability protein PilW
GKD17_RS01200	COG0724	RNA recognition motif
GKD17_RS01205	COG2066	Belongs to the glutaminase family
GKD17_RS01210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GKD17_RS01215	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKD17_RS01220	COG0509	glycine decarboxylation via glycine cleavage system
GKD17_RS01235	COG0006	proline dipeptidase activity
GKD17_RS01250	COG0572	uridine kinase
GKD17_RS01255	COG1283	sodium-dependent phosphate transmembrane transporter activity
GKD17_RS01260	COG1283	sodium-dependent phosphate transmembrane transporter activity
GKD17_RS01270	COG0545	Peptidyl-prolyl cis-trans isomerase
GKD17_RS01275	COG0545	Peptidyl-prolyl cis-trans isomerase
GKD17_RS01280	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GKD17_RS01285	COG1773	rubredoxin
GKD17_RS01290	COG1185	polyribonucleotide nucleotidyltransferase activity
GKD17_RS01300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GKD17_RS01335	COG0358	DNA primase activity
GKD17_RS01375	COG4804	nuclease activity
GKD17_RS01380	COG4974	Belongs to the 'phage' integrase family
GKD17_RS01490	COG3189	MarR family transcriptional regulator
GKD17_RS01495	COG0439	Biotin carboxylase
GKD17_RS01505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKD17_RS01520	COG2096	Adenosyltransferase
GKD17_RS01595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKD17_RS01600	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GKD17_RS01605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKD17_RS01615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKD17_RS01620	COG1519	Transferase
GKD17_RS01665	COG1022	Amp-dependent synthetase and ligase
GKD17_RS01675	COG2954	triphosphatase activity
GKD17_RS01700	COG0733	neurotransmitter:sodium symporter activity
GKD17_RS01710	COG1785	Belongs to the alkaline phosphatase family
GKD17_RS01730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GKD17_RS01735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKD17_RS01740	COG1663	tetraacyldisaccharide 4'-kinase activity
GKD17_RS01745	COG0616	signal peptide processing
GKD17_RS01795	COG0811	peptide transport
GKD17_RS01825	COG1131	(ABC) transporter
GKD17_RS01845	COG0534	Mate efflux family protein
GKD17_RS01855	COG1187	pseudouridine synthase activity
GKD17_RS01860	COG0017	Asparaginyl-tRNA synthetase
GKD17_RS01880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKD17_RS01885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GKD17_RS01890	COG0052	Belongs to the universal ribosomal protein uS2 family
GKD17_RS01895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKD17_RS01905	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKD17_RS01910	COG0179	Fumarylacetoacetate (FAA) hydrolase
GKD17_RS01915	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GKD17_RS01920	COG1575	Belongs to the MenA family. Type 1 subfamily
GKD17_RS01935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKD17_RS01945	COG0194	GDP metabolic process
GKD17_RS01955	COG1214	PFAM Peptidase M22, glycoprotease
GKD17_RS01965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKD17_RS01970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKD17_RS01975	COG0739	heme binding
GKD17_RS01980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GKD17_RS01985	COG0750	zinc metalloprotease
GKD17_RS02000	COG1272	protein, Hemolysin III
GKD17_RS02005	COG0617	tRNA 3'-terminal CCA addition
GKD17_RS02015	COG0632	four-way junction helicase activity
GKD17_RS02020	COG0673	inositol 2-dehydrogenase activity
GKD17_RS02025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKD17_RS02040	COG1621	beta-fructofuranosidase activity
GKD17_RS02050	COG1105	Belongs to the carbohydrate kinase PfkB family
GKD17_RS02055	COG3292	Two component regulator propeller
GKD17_RS02055	COG2205	protein histidine kinase activity
GKD17_RS02055	COG0745	RESPONSE REGULATOR receiver
GKD17_RS02065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GKD17_RS02075	COG0254	rRNA binding
GKD17_RS02080	COG0191	fructose-bisphosphate aldolase activity
GKD17_RS02125	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GKD17_RS02125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKD17_RS02135	COG0563	adenylate kinase activity
GKD17_RS02140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKD17_RS02180	COG0138	bifunctional purine biosynthesis protein purh
GKD17_RS02225	COG1482	cell wall glycoprotein biosynthetic process
GKD17_RS02230	COG2706	6-phosphogluconolactonase activity
GKD17_RS02245	COG0523	cobalamin synthesis protein
GKD17_RS02260	COG4771	TonB-dependent receptor
GKD17_RS02265	COG2205	protein histidine kinase activity
GKD17_RS02265	COG0745	RESPONSE REGULATOR receiver
GKD17_RS02265	COG3292	Two component regulator propeller
GKD17_RS02285	COG4999	Histidine kinase
GKD17_RS02285	COG2205	protein histidine kinase activity
GKD17_RS02285	COG3850	Histidine kinase
GKD17_RS02285	COG3437	response regulator, receiver
GKD17_RS02290	COG5002	protein histidine kinase activity
GKD17_RS02295	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS02300	COG1007	ATP synthesis coupled electron transport
GKD17_RS02305	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKD17_RS02310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GKD17_RS02320	COG0839	Belongs to the complex I subunit 6 family
GKD17_RS02325	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKD17_RS02330	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GKD17_RS02335	COG0649	NAD binding
GKD17_RS02340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKD17_RS02345	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GKD17_RS02350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKD17_RS02355	COG0569	domain protein
GKD17_RS02360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKD17_RS02370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKD17_RS02385	COG3250	beta-galactosidase activity
GKD17_RS02400	COG3119	arylsulfatase activity
GKD17_RS02405	COG0702	epimerase
GKD17_RS02410	COG1629	transport
GKD17_RS02410	COG4206	TonB-dependent receptor
GKD17_RS02445	COG4206	TonB-dependent receptor
GKD17_RS02445	COG1629	transport
GKD17_RS02485	COG4206	TonB-dependent receptor
GKD17_RS02485	COG1629	transport
GKD17_RS02490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS02495	COG1082	Xylose isomerase domain protein TIM barrel
GKD17_RS02500	COG3292	Two component regulator propeller
GKD17_RS02500	COG2205	protein histidine kinase activity
GKD17_RS02500	COG0745	RESPONSE REGULATOR receiver
GKD17_RS02510	COG3250	beta-galactosidase activity
GKD17_RS02515	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS02525	COG3940	Belongs to the glycosyl hydrolase 43 family
GKD17_RS02525	COG3940	Belongs to the glycosyl hydrolase 43 family
GKD17_RS02535	COG4771	TonB-dependent receptor
GKD17_RS02555	COG0745	RESPONSE REGULATOR receiver
GKD17_RS02555	COG2205	protein histidine kinase activity
GKD17_RS02555	COG3292	Two component regulator propeller
GKD17_RS02560	COG1012	belongs to the aldehyde dehydrogenase family
GKD17_RS02585	COG2271	Major facilitator Superfamily
GKD17_RS02590	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GKD17_RS02595	COG3775	system Galactitol-specific IIC component
GKD17_RS02600	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS02605	COG4677	pectinesterase activity
GKD17_RS02610	COG1629	transport
GKD17_RS02620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GKD17_RS02620	COG0515	serine threonine protein kinase
GKD17_RS02625	COG4771	TonB-dependent receptor
GKD17_RS02630	COG0702	epimerase
GKD17_RS02635	COG3507	Belongs to the glycosyl hydrolase 43 family
GKD17_RS02665	COG4771	TonB-dependent receptor
GKD17_RS02695	COG1917	Cupin 2, conserved barrel domain protein
GKD17_RS02710	COG2755	lipolytic protein G-D-S-L family
GKD17_RS02715	COG2205	protein histidine kinase activity
GKD17_RS02715	COG3292	Two component regulator propeller
GKD17_RS02715	COG0745	RESPONSE REGULATOR receiver
GKD17_RS02725	COG1506	peptidase
GKD17_RS02725	COG0823	Involved in the tonB-independent uptake of proteins
GKD17_RS02740	COG0138	bifunctional purine biosynthesis protein purh
GKD17_RS02760	COG0768	penicillin binding
GKD17_RS02765	COG0772	Belongs to the SEDS family
GKD17_RS02775	COG1774	PSP1 C-terminal conserved region
GKD17_RS02780	COG0470	DNA polymerase III
GKD17_RS02785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GKD17_RS02805	COG0628	permease
GKD17_RS02810	COG1435	thymidine kinase activity
GKD17_RS02815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKD17_RS02835	COG1629	transport
GKD17_RS02845	COG1629	transport
GKD17_RS02845	COG4206	TonB-dependent receptor
GKD17_RS02850	COG4974	Belongs to the 'phage' integrase family
GKD17_RS02860	COG1629	transport
GKD17_RS02860	COG4206	TonB-dependent receptor
GKD17_RS02875	COG4771	TonB-dependent receptor
GKD17_RS02885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKD17_RS02900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GKD17_RS02900	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GKD17_RS02910	COG0531	amino acid
GKD17_RS02920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GKD17_RS02925	COG1566	PFAM secretion protein HlyD family protein
GKD17_RS02935	COG1162	GTPase activity
GKD17_RS02940	COG0233	cytoplasmic translational termination
GKD17_RS02960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS02965	COG0528	UMP kinase activity
GKD17_RS02970	COG0534	Mate efflux family protein
GKD17_RS02980	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GKD17_RS02980	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GKD17_RS02990	COG0792	nuclease activity
GKD17_RS03010	COG1183	phosphatidylcholine synthase activity
GKD17_RS03015	COG0688	phosphatidylethanolamine metabolic process
GKD17_RS03045	COG0802	atpase or kinase
GKD17_RS03050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GKD17_RS03065	COG1830	Aldolase
GKD17_RS03070	COG0588	phosphoglycerate mutase activity
GKD17_RS03085	COG0475	glutathione-regulated potassium exporter activity
GKD17_RS03155	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GKD17_RS03170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKD17_RS03175	COG0742	ribosomal rna small subunit methyltransferase
GKD17_RS03190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKD17_RS03195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKD17_RS03200	COG0739	heme binding
GKD17_RS03210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKD17_RS03215	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKD17_RS03215	COG1388	LysM domain
GKD17_RS03225	COG1475	DNA binding
GKD17_RS03230	COG1192	Involved in chromosome partitioning
GKD17_RS03235	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GKD17_RS03240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKD17_RS03255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKD17_RS03270	COG1196	nuclear chromosome segregation
GKD17_RS03275	COG2239	Acts as a magnesium transporter
GKD17_RS03280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GKD17_RS03290	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKD17_RS03295	COG0590	tRNA wobble adenosine to inosine editing
GKD17_RS03300	COG1396	sequence-specific DNA binding
GKD17_RS03310	COG3550	peptidyl-serine autophosphorylation
GKD17_RS03315	COG2373	Large extracellular alpha-helical protein
GKD17_RS03335	COG0205	6-phosphofructokinase activity
GKD17_RS03340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GKD17_RS03345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GKD17_RS03360	COG0084	hydrolase, TatD family'
GKD17_RS03370	COG0811	peptide transport
GKD17_RS03400	COG1522	sequence-specific DNA binding
GKD17_RS03410	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKD17_RS03420	COG1595	DNA-templated transcription, initiation
GKD17_RS03430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKD17_RS03430	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GKD17_RS03455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKD17_RS03460	COG0538	isocitrate dehydrogenase activity
GKD17_RS03465	COG0372	Belongs to the citrate synthase family
GKD17_RS03505	COG1902	pentaerythritol trinitrate reductase activity
GKD17_RS03535	COG0205	6-phosphofructokinase activity
GKD17_RS03540	COG0546	phosphoglycolate phosphatase activity
GKD17_RS03555	COG0511	ligase activity, forming carbon-carbon bonds
GKD17_RS03560	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GKD17_RS03565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS03575	COG0561	phosphatase activity
GKD17_RS03580	COG4771	TonB-dependent receptor
GKD17_RS03610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GKD17_RS03630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GKD17_RS03635	COG1506	peptidase
GKD17_RS03635	COG0823	Involved in the tonB-independent uptake of proteins
GKD17_RS03640	COG1242	4 iron, 4 sulfur cluster binding
GKD17_RS03645	COG0426	domain, Protein
GKD17_RS03650	COG0668	transmembrane transport
GKD17_RS03655	COG0009	L-threonylcarbamoyladenylate synthase
GKD17_RS03660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKD17_RS03720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKD17_RS03725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKD17_RS03730	COG0066	3-isopropylmalate dehydratase activity
GKD17_RS03735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKD17_RS03740	COG0473	3-isopropylmalate dehydrogenase activity
GKD17_RS03750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKD17_RS03760	COG0514	ATP-dependent DNA helicase (RecQ)
GKD17_RS03780	COG0735	belongs to the Fur family
GKD17_RS03785	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKD17_RS03795	COG4771	TonB-dependent receptor
GKD17_RS03810	COG2755	lipolytic protein G-D-S-L family
GKD17_RS03825	COG4206	TonB-dependent receptor
GKD17_RS03825	COG1629	transport
GKD17_RS03830	COG0702	epimerase
GKD17_RS03845	COG0488	(ABC) transporter
GKD17_RS03850	COG3590	peptidase
GKD17_RS03860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS03875	COG0673	inositol 2-dehydrogenase activity
GKD17_RS03880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GKD17_RS03885	COG0826	peptidase U32
GKD17_RS03895	COG4771	TonB-dependent receptor
GKD17_RS03910	COG0095	Lipoate-protein ligase
GKD17_RS03915	COG0508	dehydrogenase complex catalyzes the overall conversion of
GKD17_RS03920	COG0022	dehydrogenase e1 component
GKD17_RS03925	COG0716	FMN binding
GKD17_RS03930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GKD17_RS03940	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKD17_RS03955	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GKD17_RS03960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GKD17_RS03965	COG1120	ATPase activity
GKD17_RS03970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKD17_RS03995	COG1073	alpha beta
GKD17_RS04015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GKD17_RS04020	COG0436	Aminotransferase
GKD17_RS04030	COG1733	regulation of RNA biosynthetic process
GKD17_RS04040	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GKD17_RS04045	COG0628	permease
GKD17_RS04055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS04060	COG0514	ATP-dependent DNA helicase (RecQ)
GKD17_RS04065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GKD17_RS04065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GKD17_RS04075	COG0006	proline dipeptidase activity
GKD17_RS04090	COG1418	mRNA catabolic process
GKD17_RS04105	COG2832	Protein of unknown function (DUF454)
GKD17_RS04115	COG0602	queuosine metabolic process
GKD17_RS04135	COG1115	amino acid carrier protein
GKD17_RS04145	COG0745	RESPONSE REGULATOR receiver
GKD17_RS04145	COG3292	Two component regulator propeller
GKD17_RS04145	COG2205	protein histidine kinase activity
GKD17_RS04155	COG3681	Belongs to the UPF0597 family
GKD17_RS04195	COG4771	TonB-dependent receptor
GKD17_RS04200	COG0702	epimerase
GKD17_RS04205	COG3250	beta-galactosidase activity
GKD17_RS04210	COG0745	RESPONSE REGULATOR receiver
GKD17_RS04210	COG3292	Two component regulator propeller
GKD17_RS04210	COG2205	protein histidine kinase activity
GKD17_RS04235	COG4771	TonB-dependent receptor
GKD17_RS04320	COG1629	transport
GKD17_RS04320	COG4206	TonB-dependent receptor
GKD17_RS04330	COG0126	phosphoglycerate kinase activity
GKD17_RS04340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS04360	COG0534	Mate efflux family protein
GKD17_RS04365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKD17_RS04370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKD17_RS04395	COG1629	transport
GKD17_RS04405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS04425	COG0745	RESPONSE REGULATOR receiver
GKD17_RS04425	COG2205	protein histidine kinase activity
GKD17_RS04425	COG3292	Two component regulator propeller
GKD17_RS04430	COG4771	TonB-dependent receptor
GKD17_RS04480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKD17_RS04495	COG0321	lipoyl(octanoyl) transferase activity
GKD17_RS04495	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GKD17_RS04500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKD17_RS04505	COG1834	amidinotransferase
GKD17_RS04515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKD17_RS04525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GKD17_RS04540	COG4413	Urea transporter
GKD17_RS04545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKD17_RS04560	COG3591	Belongs to the peptidase S1B family
GKD17_RS04565	COG3591	Belongs to the peptidase S1B family
GKD17_RS04580	COG1408	metallophosphoesterase
GKD17_RS04585	COG1410	methionine synthase
GKD17_RS04585	COG0646	methionine synthase
GKD17_RS04590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GKD17_RS04595	COG0463	Glycosyl transferase, family 2
GKD17_RS04640	COG2311	Membrane
GKD17_RS04645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKD17_RS04665	COG0318	PFAM AMP-dependent synthetase and ligase
GKD17_RS04745	COG1215	transferase activity, transferring glycosyl groups
GKD17_RS04760	COG1216	Glycosyl transferase, family 2
GKD17_RS04760	COG1442	glycosyl transferase family 8
GKD17_RS04775	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GKD17_RS04790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKD17_RS04810	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GKD17_RS04820	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GKD17_RS04825	COG1032	radical SAM domain protein
GKD17_RS04840	COG5434	Belongs to the glycosyl hydrolase 28 family
GKD17_RS04870	COG2264	protein methyltransferase activity
GKD17_RS04925	COG0673	inositol 2-dehydrogenase activity
GKD17_RS04930	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GKD17_RS04980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKD17_RS04990	COG2160	L-arabinose isomerase activity
GKD17_RS05015	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GKD17_RS05035	COG0484	heat shock protein binding
GKD17_RS05040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKD17_RS05045	COG0488	(ABC) transporter
GKD17_RS05065	COG0393	Putative heavy-metal-binding
GKD17_RS05100	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKD17_RS05100	COG1388	LysM domain
GKD17_RS05110	COG1136	(ABC) transporter
GKD17_RS05115	COG0577	efflux transmembrane transporter activity
GKD17_RS05125	COG1136	(ABC) transporter
GKD17_RS05125	COG0577	efflux transmembrane transporter activity
GKD17_RS05135	COG0577	efflux transmembrane transporter activity
GKD17_RS05135	COG1136	(ABC) transporter
GKD17_RS05160	COG2204	response regulator
GKD17_RS05165	COG4191	Histidine kinase
GKD17_RS05185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GKD17_RS05190	COG0572	uridine kinase
GKD17_RS05205	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GKD17_RS05210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GKD17_RS05215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKD17_RS05220	COG0131	Imidazoleglycerol-phosphate dehydratase
GKD17_RS05235	COG1773	rubredoxin
GKD17_RS05235	COG1592	Rubrerythrin
GKD17_RS05245	COG3118	belongs to the thioredoxin family
GKD17_RS05260	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKD17_RS05270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKD17_RS05275	COG0157	Belongs to the NadC ModD family
GKD17_RS05280	COG3328	transposase activity
GKD17_RS05285	COG3292	Two component regulator propeller
GKD17_RS05285	COG2205	protein histidine kinase activity
GKD17_RS05285	COG0745	RESPONSE REGULATOR receiver
GKD17_RS05295	COG4771	TonB-dependent receptor
GKD17_RS05310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKD17_RS05315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GKD17_RS05335	COG0443	Heat shock 70 kDa protein
GKD17_RS05585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKD17_RS05600	COG1538	Outer membrane efflux protein
GKD17_RS05610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKD17_RS05650	COG0500	methyltransferase
GKD17_RS05685	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKD17_RS05705	COG0739	heme binding
GKD17_RS05765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKD17_RS05770	COG1705	Flagellar rod assembly protein muramidase FlgJ
GKD17_RS05800	COG1373	ATPase (AAA superfamily
GKD17_RS05855	COG3118	belongs to the thioredoxin family
GKD17_RS05910	COG1192	Involved in chromosome partitioning
GKD17_RS05915	COG0629	single-stranded DNA binding
GKD17_RS06020	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKD17_RS06055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKD17_RS06115	COG0556	nucleotide-excision repair
GKD17_RS06135	COG4948	Mandelate Racemase Muconate Lactonizing
GKD17_RS06145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GKD17_RS06150	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKD17_RS06155	COG1169	isochorismate synthase
GKD17_RS06160	COG2050	protein possibly involved in aromatic compounds catabolism
GKD17_RS06165	COG0471	metal ion transport
GKD17_RS06165	COG0490	domain, Protein
GKD17_RS06170	COG0534	Mate efflux family protein
GKD17_RS06175	COG0446	pyridine nucleotide-disulphide oxidoreductase
GKD17_RS06200	COG1518	maintenance of DNA repeat elements
GKD17_RS06205	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GKD17_RS06220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKD17_RS06230	COG4771	TonB-dependent receptor
GKD17_RS06240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS06255	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GKD17_RS06260	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GKD17_RS06265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GKD17_RS06270	COG0569	domain protein
GKD17_RS06285	COG1760	l-serine dehydratase
GKD17_RS06305	COG4771	TonB-dependent receptor
GKD17_RS06330	COG2226	methyltransferase
GKD17_RS06345	COG0582	viral genome integration into host DNA
GKD17_RS06355	COG1193	negative regulation of DNA recombination
GKD17_RS06380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GKD17_RS06380	COG2755	lipolytic protein G-D-S-L family
GKD17_RS06390	COG2217	Heavy metal translocating P-type atpase
GKD17_RS06400	COG4221	oxidoreductase activity
GKD17_RS06410	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GKD17_RS06415	COG0511	ligase activity, forming carbon-carbon bonds
GKD17_RS06425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKD17_RS06440	COG0778	Nitroreductase
GKD17_RS06455	COG0561	phosphatase activity
GKD17_RS06460	COG0424	maF-like protein
GKD17_RS06465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKD17_RS06485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS06490	COG1309	transcriptional regulator
GKD17_RS06500	COG2226	methyltransferase
GKD17_RS06500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKD17_RS06500	COG0596	Alpha beta hydrolase
GKD17_RS06505	COG1132	(ABC) transporter
GKD17_RS06600	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GKD17_RS06605	COG1410	methionine synthase
GKD17_RS06605	COG0646	methionine synthase
GKD17_RS06610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKD17_RS06620	COG2233	PERMEase
GKD17_RS06625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKD17_RS06640	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GKD17_RS06640	COG0778	Nitroreductase
GKD17_RS06650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKD17_RS06655	COG1704	LemA family
GKD17_RS06670	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKD17_RS06675	COG2226	methyltransferase
GKD17_RS06680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GKD17_RS06685	COG1702	phosphate starvation-inducible protein PhoH
GKD17_RS06695	COG0101	tRNA pseudouridine synthase activity
GKD17_RS06710	COG1047	Peptidyl-prolyl cis-trans
GKD17_RS06720	COG0129	dihydroxy-acid dehydratase activity
GKD17_RS06740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GKD17_RS06765	COG1253	flavin adenine dinucleotide binding
GKD17_RS06785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GKD17_RS06800	COG0653	protein targeting
GKD17_RS06830	COG0525	valine-tRNA ligase activity
GKD17_RS06835	COG3956	TIGRFAM MazG family protein
GKD17_RS06845	COG4771	TonB-dependent receptor
GKD17_RS06860	COG1595	DNA-templated transcription, initiation
GKD17_RS06865	COG1234	tRNA 3'-trailer cleavage
GKD17_RS06875	COG0539	negative regulation of cytoplasmic translation
GKD17_RS06885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GKD17_RS06905	COG3275	phosphorelay sensor kinase activity
GKD17_RS06925	COG4974	Belongs to the 'phage' integrase family
GKD17_RS07000	COG2207	Transcriptional regulator
GKD17_RS07005	COG2706	6-phosphogluconolactonase activity
GKD17_RS07015	COG4771	TonB-dependent receptor
GKD17_RS07020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS07065	COG0667	Aldo Keto reductase
GKD17_RS07075	COG0655	NAD(P)H dehydrogenase (quinone) activity
GKD17_RS07095	COG2095	MarC family integral membrane protein
GKD17_RS07105	COG1830	Aldolase
GKD17_RS07110	COG0588	phosphoglycerate mutase activity
GKD17_RS07125	COG0205	6-phosphofructokinase activity
GKD17_RS07130	COG4651	solute:proton antiporter activity
GKD17_RS07130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKD17_RS07135	COG0058	SHG alpha-glucan phosphorylase activity
GKD17_RS07140	COG0010	Belongs to the arginase family
GKD17_RS07145	COG1803	Methylglyoxal synthase
GKD17_RS07205	COG1215	transferase activity, transferring glycosyl groups
GKD17_RS07220	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GKD17_RS07225	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKD17_RS07250	COG0738	Major facilitator superfamily
GKD17_RS07255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKD17_RS07265	COG2204	response regulator
GKD17_RS07285	COG0708	Exodeoxyribonuclease III
GKD17_RS07300	COG1741	Belongs to the pirin family
GKD17_RS07315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GKD17_RS07325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKD17_RS07340	COG0793	Belongs to the peptidase S41A family
GKD17_RS07345	COG2131	deaminase
GKD17_RS07355	COG0339	signal peptide processing
GKD17_RS07370	COG1477	protein flavinylation
GKD17_RS07375	COG1971	Probably functions as a manganese efflux pump
GKD17_RS07390	COG0463	Glycosyl transferase, family 2
GKD17_RS07405	COG0514	ATP-dependent DNA helicase (RecQ)
GKD17_RS07415	COG0148	phosphopyruvate hydratase activity
GKD17_RS07425	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS07435	COG3408	Glycogen debranching enzyme
GKD17_RS07460	COG0662	Cupin 2, conserved barrel domain protein
GKD17_RS07460	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GKD17_RS07465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKD17_RS07470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GKD17_RS07490	COG1216	Glycosyl transferase, family 2
GKD17_RS07510	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS07575	COG3023	N-Acetylmuramoyl-L-alanine amidase
GKD17_RS07650	COG3250	beta-galactosidase activity
GKD17_RS07665	COG0490	domain, Protein
GKD17_RS07665	COG2985	domain, Protein
GKD17_RS07670	COG1629	transport
GKD17_RS07670	COG4206	TonB-dependent receptor
GKD17_RS07680	COG4771	TonB-dependent receptor
GKD17_RS07690	COG3250	beta-galactosidase activity
GKD17_RS07695	COG3250	beta-galactosidase activity
GKD17_RS07700	COG3940	Belongs to the glycosyl hydrolase 43 family
GKD17_RS07735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKD17_RS07740	COG0110	maltose O-acetyltransferase activity
GKD17_RS07765	COG1216	Glycosyl transferase, family 2
GKD17_RS07770	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS07775	COG1216	Glycosyl transferase, family 2
GKD17_RS07780	COG0463	Glycosyl transferase, family 2
GKD17_RS07785	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS07810	COG0463	Glycosyl transferase, family 2
GKD17_RS07810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GKD17_RS07815	COG1216	Glycosyl transferase, family 2
GKD17_RS07825	COG1216	Glycosyl transferase, family 2
GKD17_RS07880	COG0489	protein tyrosine kinase activity
GKD17_RS07880	COG3206	protein involved in exopolysaccharide biosynthesis
GKD17_RS07890	COG1132	(ABC) transporter
GKD17_RS07940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GKD17_RS07970	COG0598	Magnesium transport protein CorA
GKD17_RS07975	COG1522	sequence-specific DNA binding
GKD17_RS07985	COG0586	Pfam SNARE associated Golgi protein
GKD17_RS07995	COG0306	phosphate transporter
GKD17_RS08005	COG4771	TonB-dependent receptor
GKD17_RS08015	COG2873	o-acetylhomoserine
GKD17_RS08020	COG1620	l-lactate permease
GKD17_RS08040	COG2205	protein histidine kinase activity
GKD17_RS08075	COG0668	transmembrane transport
GKD17_RS08080	COG0318	PFAM AMP-dependent synthetase and ligase
GKD17_RS08090	COG0307	riboflavin synthase, alpha
GKD17_RS08095	COG1295	ribonuclease BN
GKD17_RS08115	COG0484	heat shock protein binding
GKD17_RS08125	COG0737	Belongs to the 5'-nucleotidase family
GKD17_RS08135	COG4771	TonB-dependent receptor
GKD17_RS08140	COG1509	lysine 2,3-aminomutase activity
GKD17_RS08150	COG3408	Glycogen debranching enzyme
GKD17_RS08165	COG2205	protein histidine kinase activity
GKD17_RS08165	COG0784	Response regulator, receiver
GKD17_RS08175	COG3059	membrane
GKD17_RS08180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKD17_RS08185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GKD17_RS08205	COG1914	H( )-stimulated, divalent metal cation uptake system
GKD17_RS08210	COG3263	regulation of cellular component size
GKD17_RS08215	COG0534	Mate efflux family protein
GKD17_RS08225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GKD17_RS08235	COG0488	(ABC) transporter
GKD17_RS08315	COG0228	four-way junction DNA binding
GKD17_RS08325	COG2755	lipolytic protein G-D-S-L family
GKD17_RS08325	COG0657	acetylesterase activity
GKD17_RS08350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GKD17_RS08355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKD17_RS08390	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GKD17_RS08395	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GKD17_RS08395	COG1333	cytochrome c biogenesis protein
GKD17_RS08415	COG1730	sister chromatid segregation
GKD17_RS08430	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS08445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GKD17_RS08445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GKD17_RS08450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GKD17_RS08450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GKD17_RS08465	COG2226	methyltransferase
GKD17_RS08480	COG0004	ammonium transporteR
GKD17_RS08485	COG0347	Belongs to the P(II) protein family
GKD17_RS08495	COG0436	Aminotransferase
GKD17_RS08500	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GKD17_RS08505	COG1119	ATPase activity
GKD17_RS08510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKD17_RS08515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GKD17_RS08525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GKD17_RS08530	COG0252	asparaginase activity
GKD17_RS08555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GKD17_RS08560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GKD17_RS08565	COG0363	glucosamine-6-phosphate deaminase activity
GKD17_RS08575	COG1271	oxidase subunit
GKD17_RS08590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS08595	COG1136	(ABC) transporter
GKD17_RS08600	COG1136	(ABC) transporter
GKD17_RS08600	COG0577	efflux transmembrane transporter activity
GKD17_RS08610	COG3279	Response regulator of the LytR AlgR family
GKD17_RS08625	COG4566	intracellular signal transduction
GKD17_RS08630	COG0247	lactate metabolic process
GKD17_RS08635	COG1139	Iron-sulfur cluster binding protein
GKD17_RS08650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKD17_RS08685	COG0259	pyridoxamine-phosphate oxidase activity
GKD17_RS08695	COG1918	ferrous iron import across plasma membrane
GKD17_RS08695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GKD17_RS08710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKD17_RS08715	COG0497	DNA recombination
GKD17_RS08755	COG0297	glycogen (starch) synthase activity
GKD17_RS08760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GKD17_RS08765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GKD17_RS08770	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GKD17_RS08780	COG2816	NAD+ diphosphatase activity
GKD17_RS08785	COG2183	response to ionizing radiation
GKD17_RS08790	COG3250	beta-galactosidase activity
GKD17_RS08795	COG2205	protein histidine kinase activity
GKD17_RS08795	COG3292	Two component regulator propeller
GKD17_RS08795	COG0745	RESPONSE REGULATOR receiver
GKD17_RS08805	COG4206	TonB-dependent receptor
GKD17_RS08805	COG1629	transport
GKD17_RS08810	COG0702	epimerase
GKD17_RS08850	COG4771	TonB-dependent receptor
GKD17_RS08865	COG1629	transport
GKD17_RS08895	COG5012	cobalamin binding
GKD17_RS08900	COG1501	Belongs to the glycosyl hydrolase 31 family
GKD17_RS08940	COG0488	(ABC) transporter
GKD17_RS08965	COG1216	Glycosyl transferase, family 2
GKD17_RS09010	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS09070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GKD17_RS09080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKD17_RS09095	COG1678	Uncharacterized ACR, COG1678
GKD17_RS09105	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09105	COG3292	Two component regulator propeller
GKD17_RS09105	COG2205	protein histidine kinase activity
GKD17_RS09105	COG2205	protein histidine kinase activity
GKD17_RS09105	COG3292	Two component regulator propeller
GKD17_RS09105	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09115	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GKD17_RS09120	COG1151	hydroxylamine reductase activity
GKD17_RS09130	COG3119	arylsulfatase activity
GKD17_RS09140	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09145	COG5002	protein histidine kinase activity
GKD17_RS09165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKD17_RS09170	COG0248	Ppx GppA phosphatase
GKD17_RS09180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKD17_RS09195	COG0356	it plays a direct role in the translocation of protons across the membrane
GKD17_RS09200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKD17_RS09205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKD17_RS09210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKD17_RS09215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKD17_RS09220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKD17_RS09235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GKD17_RS09245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GKD17_RS09250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKD17_RS09270	COG3973	AAA domain
GKD17_RS09280	COG2198	Histidine kinase
GKD17_RS09280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS09280	COG0784	Response regulator, receiver
GKD17_RS09280	COG2205	protein histidine kinase activity
GKD17_RS09295	COG4206	TonB-dependent receptor
GKD17_RS09305	COG1064	alcohol dehydrogenase
GKD17_RS09310	COG1454	alcohol dehydrogenase
GKD17_RS09315	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS09325	COG0110	maltose O-acetyltransferase activity
GKD17_RS09345	COG0110	maltose O-acetyltransferase activity
GKD17_RS09385	COG2855	membrane
GKD17_RS09405	COG1979	alcohol dehydrogenase
GKD17_RS09410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GKD17_RS09430	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKD17_RS09430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GKD17_RS09435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GKD17_RS09440	COG0357	Ribosomal RNA small subunit methyltransferase G
GKD17_RS09450	COG2217	Heavy metal translocating P-type atpase
GKD17_RS09460	COG0582	viral genome integration into host DNA
GKD17_RS09465	COG4974	Belongs to the 'phage' integrase family
GKD17_RS09490	COG2204	response regulator
GKD17_RS09495	COG2205	protein histidine kinase activity
GKD17_RS09495	COG2198	Histidine kinase
GKD17_RS09495	COG0784	Response regulator, receiver
GKD17_RS09495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS09505	COG3250	beta-galactosidase activity
GKD17_RS09535	COG4771	TonB-dependent receptor
GKD17_RS09540	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09540	COG3292	Two component regulator propeller
GKD17_RS09540	COG2205	protein histidine kinase activity
GKD17_RS09550	COG2755	lipolytic protein G-D-S-L family
GKD17_RS09565	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS09605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKD17_RS09605	COG0551	DNA topoisomerase type I activity
GKD17_RS09620	COG1373	ATPase (AAA superfamily
GKD17_RS09740	COG4974	Belongs to the 'phage' integrase family
GKD17_RS09850	COG0584	glycerophosphoryl diester phosphodiesterase
GKD17_RS09855	COG0702	epimerase
GKD17_RS09860	COG4771	TonB-dependent receptor
GKD17_RS09875	COG4804	nuclease activity
GKD17_RS09880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GKD17_RS09920	COG3546	catalase activity
GKD17_RS09935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GKD17_RS09950	COG2205	protein histidine kinase activity
GKD17_RS09950	COG2205	protein histidine kinase activity
GKD17_RS09950	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09950	COG3292	Two component regulator propeller
GKD17_RS09950	COG3292	Two component regulator propeller
GKD17_RS09950	COG0745	RESPONSE REGULATOR receiver
GKD17_RS09990	COG1192	Involved in chromosome partitioning
GKD17_RS10005	COG3177	Filamentation induced by cAMP protein fic
GKD17_RS10030	COG0741	lytic transglycosylase activity
GKD17_RS10030	COG0739	heme binding
GKD17_RS10030	COG1196	nuclear chromosome segregation
GKD17_RS10305	COG0321	lipoyl(octanoyl) transferase activity
GKD17_RS10310	COG1022	Amp-dependent synthetase and ligase
GKD17_RS10315	COG1252	NADH dehydrogenase
GKD17_RS10350	COG3617	BRO family, N-terminal domain
GKD17_RS10370	COG4974	Belongs to the 'phage' integrase family
GKD17_RS10410	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GKD17_RS10415	COG1523	belongs to the glycosyl hydrolase 13 family
GKD17_RS10420	COG1312	Catalyzes the dehydration of D-mannonate
GKD17_RS10425	COG1752	Esterase of the alpha-beta hydrolase superfamily
GKD17_RS10430	COG2176	DNA-directed DNA polymerase activity
GKD17_RS10435	COG1739	Uncharacterized protein family UPF0029
GKD17_RS10445	COG0556	nucleotide-excision repair
GKD17_RS10470	COG3942	CHAP domain
GKD17_RS10470	COG1388	LysM domain
GKD17_RS10480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKD17_RS10485	COG3104	oligopeptide transport
GKD17_RS10490	COG2431	L-lysine efflux transmembrane transporter activity
GKD17_RS10505	COG1757	Na H antiporter
GKD17_RS10510	COG2721	sulfolactate sulfo-lyase activity
GKD17_RS10515	COG1609	Transcriptional regulator
GKD17_RS10530	COG0501	Belongs to the peptidase M48B family
GKD17_RS10540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKD17_RS10550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKD17_RS10565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKD17_RS10605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GKD17_RS10620	COG1904	glucuronate isomerase
GKD17_RS10625	COG0246	Mannitol dehydrogenase
GKD17_RS10645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKD17_RS10650	COG1120	ATPase activity
GKD17_RS10655	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GKD17_RS10685	COG2207	Transcriptional regulator
GKD17_RS10685	COG0662	Cupin 2, conserved barrel domain protein
GKD17_RS10690	COG2207	Transcriptional regulator
GKD17_RS10690	COG4753	response regulator
GKD17_RS10695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GKD17_RS10705	COG4771	TonB-dependent receptor
GKD17_RS10715	COG4771	TonB-dependent receptor
GKD17_RS10720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GKD17_RS10725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKD17_RS10730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKD17_RS10750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GKD17_RS10760	COG0439	Biotin carboxylase
GKD17_RS10785	COG4771	TonB-dependent receptor
GKD17_RS10790	COG4771	TonB-dependent receptor
GKD17_RS10800	COG1797	cobyrinic acid a,c-diamide synthase activity
GKD17_RS10805	COG2096	Adenosyltransferase
GKD17_RS10810	COG1492	cobalamin metabolic process
GKD17_RS10820	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GKD17_RS10845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GKD17_RS10880	COG0513	Belongs to the DEAD box helicase family
GKD17_RS10885	COG3830	Belongs to the UPF0237 family
GKD17_RS10885	COG0560	Phosphoserine phosphatase
GKD17_RS10895	COG1011	Hydrolase
GKD17_RS10905	COG0343	queuine tRNA-ribosyltransferase activity
GKD17_RS10910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GKD17_RS10915	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GKD17_RS10920	COG1597	lipid kinase activity
GKD17_RS10925	COG0156	8-amino-7-oxononanoate synthase activity
GKD17_RS10940	COG1136	(ABC) transporter
GKD17_RS10965	COG3328	transposase activity
GKD17_RS10995	COG3852	Histidine kinase
GKD17_RS11005	COG4771	TonB-dependent receptor
GKD17_RS11025	COG2814	Major facilitator Superfamily
GKD17_RS11075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GKD17_RS11080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKD17_RS11115	COG3579	cysteine-type endopeptidase activity
GKD17_RS11130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKD17_RS11155	COG3959	Transketolase, thiamine diphosphate binding domain
GKD17_RS11160	COG3958	Transketolase
GKD17_RS11200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKD17_RS11240	COG1805	sodium ion transport
GKD17_RS11245	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GKD17_RS11250	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GKD17_RS11255	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GKD17_RS11265	COG0513	Belongs to the DEAD box helicase family
GKD17_RS11270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKD17_RS11275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKD17_RS11305	COG4106	trans-aconitate 2-methyltransferase activity
GKD17_RS11310	COG1733	regulation of RNA biosynthetic process
GKD17_RS11320	COG0494	nUDIX hydrolase
GKD17_RS11330	COG2205	protein histidine kinase activity
GKD17_RS11340	COG3328	transposase activity
GKD17_RS11345	COG1285	pathogenesis
GKD17_RS11355	COG0561	phosphatase activity
GKD17_RS11370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS11380	COG3387	PFAM Glycoside hydrolase 15-related
GKD17_RS11410	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GKD17_RS11415	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GKD17_RS11420	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GKD17_RS11430	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GKD17_RS11435	COG2204	response regulator
GKD17_RS11445	COG4176	ABC-type proline glycine betaine transport system permease component
GKD17_RS11455	COG0697	spore germination
GKD17_RS11460	COG0110	maltose O-acetyltransferase activity
GKD17_RS11470	COG0024	Methionine aminopeptidase
GKD17_RS11475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKD17_RS11485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GKD17_RS11490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GKD17_RS11500	COG0552	protein localization to endoplasmic reticulum
GKD17_RS11505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKD17_RS11510	COG0776	regulation of translation
GKD17_RS11515	COG0776	regulation of translation
GKD17_RS11520	COG0714	Associated with various cellular activities
GKD17_RS11535	COG2304	oxidoreductase activity
GKD17_RS11560	COG0671	phosphoesterase, PA-phosphatase related
GKD17_RS11585	COG0542	response to heat
GKD17_RS11595	COG1752	Esterase of the alpha-beta hydrolase superfamily
GKD17_RS11615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKD17_RS11620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKD17_RS11625	COG0336	Belongs to the RNA methyltransferase TrmD family
GKD17_RS11630	COG0167	dihydroorotate dehydrogenase activity
GKD17_RS11635	COG0543	2 iron, 2 sulfur cluster binding
GKD17_RS11650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKD17_RS11665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKD17_RS11675	COG0390	transport system, permease component
GKD17_RS11680	COG1131	(ABC) transporter
GKD17_RS11685	COG0442	prolyl-tRNA aminoacylation
GKD17_RS11695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKD17_RS11725	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GKD17_RS11745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS11750	COG1131	(ABC) transporter
GKD17_RS11755	COG0842	Transport permease protein
GKD17_RS11760	COG0842	Transport permease protein
GKD17_RS11760	COG1129	ABC transporter
GKD17_RS11775	COG0784	Response regulator, receiver
GKD17_RS11775	COG5002	protein histidine kinase activity
GKD17_RS11775	COG2198	Histidine kinase
GKD17_RS11790	COG0540	Belongs to the ATCase OTCase family
GKD17_RS11795	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GKD17_RS11810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKD17_RS11815	COG0534	Mate efflux family protein
GKD17_RS11820	COG2885	chlorophyll binding
GKD17_RS11825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GKD17_RS11860	COG0504	CTP synthase activity
GKD17_RS11865	COG0706	membrane insertase activity
GKD17_RS11870	COG1506	peptidase
GKD17_RS11870	COG0823	Involved in the tonB-independent uptake of proteins
GKD17_RS11875	COG0564	pseudouridine synthase activity
GKD17_RS11880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKD17_RS11885	COG0574	Belongs to the PEP-utilizing enzyme family
GKD17_RS11885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKD17_RS11945	COG1192	Involved in chromosome partitioning
GKD17_RS12065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKD17_RS12130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKD17_RS12190	COG0358	DNA primase activity
GKD17_RS12210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GKD17_RS12220	COG3328	transposase activity
GKD17_RS12230	COG1136	(ABC) transporter
GKD17_RS12230	COG0577	efflux transmembrane transporter activity
GKD17_RS12240	COG0339	signal peptide processing
GKD17_RS12260	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS12270	COG1216	Glycosyl transferase, family 2
GKD17_RS12310	COG0386	Belongs to the glutathione peroxidase family
GKD17_RS12320	COG4191	Histidine kinase
GKD17_RS12335	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GKD17_RS12340	COG0305	Participates in initiation and elongation during chromosome replication
GKD17_RS12345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKD17_RS12345	COG0072	phenylalanine-tRNA ligase activity
GKD17_RS12350	COG0217	transcriptional regulatory protein
GKD17_RS12370	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS12385	COG0535	radical SAM domain protein
GKD17_RS12450	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS12470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GKD17_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS12500	COG0577	efflux transmembrane transporter activity
GKD17_RS12505	COG0577	efflux transmembrane transporter activity
GKD17_RS12505	COG1136	(ABC) transporter
GKD17_RS12525	COG3852	Histidine kinase
GKD17_RS12530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GKD17_RS12530	COG3153	acetyltransferase
GKD17_RS12590	COG0352	thiamine-phosphate diphosphorylase activity
GKD17_RS12595	COG2022	thiamine diphosphate biosynthetic process
GKD17_RS12600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GKD17_RS12620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GKD17_RS12625	COG0754	glutathionylspermidine amidase activity
GKD17_RS12635	COG0352	thiamine-phosphate diphosphorylase activity
GKD17_RS12640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKD17_RS12650	COG1177	transmembrane transport
GKD17_RS12680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS12685	COG0058	SHG alpha-glucan phosphorylase activity
GKD17_RS12695	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKD17_RS12700	COG1269	ATP hydrolysis coupled proton transport
GKD17_RS12715	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GKD17_RS12765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS12805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GKD17_RS12810	COG1597	lipid kinase activity
GKD17_RS12815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKD17_RS12825	COG1970	mechanosensitive ion channel activity
GKD17_RS12830	COG0519	Catalyzes the synthesis of GMP from XMP
GKD17_RS12830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GKD17_RS12835	COG0519	Catalyzes the synthesis of GMP from XMP
GKD17_RS12850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS12880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS12895	COG3119	arylsulfatase activity
GKD17_RS12935	COG4206	TonB-dependent receptor
GKD17_RS12935	COG1629	transport
GKD17_RS12960	COG1595	DNA-templated transcription, initiation
GKD17_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
GKD17_RS13005	COG2211	Major facilitator Superfamily
GKD17_RS13055	COG1408	metallophosphoesterase
GKD17_RS13060	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GKD17_RS13075	COG1674	ftsk spoiiie
GKD17_RS13085	COG0492	ferredoxin-NADP+ reductase activity
GKD17_RS13090	COG0612	Peptidase, M16
GKD17_RS13100	COG1131	(ABC) transporter
GKD17_RS13105	COG0791	NLP P60 protein
GKD17_RS13110	COG0546	phosphoglycolate phosphatase activity
GKD17_RS13115	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GKD17_RS13120	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GKD17_RS13135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKD17_RS13145	COG0543	2 iron, 2 sulfur cluster binding
GKD17_RS13170	COG0037	tRNA processing
GKD17_RS13185	COG4864	UPF0365 protein
GKD17_RS13190	COG0813	purine-nucleoside phosphorylase activity
GKD17_RS13200	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKD17_RS13210	COG4974	Belongs to the 'phage' integrase family
GKD17_RS13280	COG0110	maltose O-acetyltransferase activity
GKD17_RS13285	COG1064	alcohol dehydrogenase
GKD17_RS13300	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS13320	COG2207	Transcriptional regulator
GKD17_RS13325	COG0582	viral genome integration into host DNA
GKD17_RS13375	COG3586	endonuclease activity
GKD17_RS13380	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GKD17_RS13460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKD17_RS13495	COG0084	hydrolase, TatD family'
GKD17_RS13505	COG0537	adenosine 5'-monophosphoramidase activity
GKD17_RS13600	COG0778	Nitroreductase
GKD17_RS13715	COG1063	alcohol dehydrogenase
GKD17_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS13735	COG0346	lactoylglutathione lyase activity
GKD17_RS13750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GKD17_RS13775	COG0564	pseudouridine synthase activity
GKD17_RS13780	COG0534	Mate efflux family protein
GKD17_RS13800	COG1538	Outer membrane efflux protein
GKD17_RS13880	COG3279	Response regulator of the LytR AlgR family
GKD17_RS13885	COG3275	phosphorelay sensor kinase activity
GKD17_RS13900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKD17_RS13910	COG0739	heme binding
GKD17_RS13915	COG0686	Belongs to the AlaDH PNT family
GKD17_RS13920	COG0805	protein transport
GKD17_RS13925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKD17_RS13945	COG2855	membrane
GKD17_RS13950	COG0583	DNA-binding transcription factor activity
GKD17_RS13960	COG0542	response to heat
GKD17_RS13980	COG1862	Preprotein translocase
GKD17_RS13985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKD17_RS13995	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GKD17_RS14000	COG0193	aminoacyl-tRNA hydrolase activity
GKD17_RS14015	COG4651	solute:proton antiporter activity
GKD17_RS14015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKD17_RS14020	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GKD17_RS14025	COG2195	Cleaves the N-terminal amino acid of tripeptides
GKD17_RS14030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKD17_RS14035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GKD17_RS14045	COG2205	protein histidine kinase activity
GKD17_RS14045	COG0745	RESPONSE REGULATOR receiver
GKD17_RS14045	COG3292	Two component regulator propeller
GKD17_RS14125	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS14130	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS14135	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS14140	COG3250	beta-galactosidase activity
GKD17_RS14200	COG0805	protein transport
GKD17_RS14205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKD17_RS14240	COG0667	Aldo Keto reductase
GKD17_RS14245	COG2311	Membrane
GKD17_RS14250	COG0697	spore germination
GKD17_RS14265	COG0667	Aldo Keto reductase
GKD17_RS14270	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS14300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GKD17_RS14305	COG0534	Mate efflux family protein
GKD17_RS14330	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS14340	COG0667	Aldo Keto reductase
GKD17_RS14365	COG0788	formyltetrahydrofolate deformylase activity
GKD17_RS14375	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GKD17_RS14380	COG0107	imidazoleglycerol-phosphate synthase activity
GKD17_RS14385	COG0140	phosphoribosyl-ATP diphosphatase activity
GKD17_RS14385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GKD17_RS14390	COG2884	Cell division ATP-binding protein ftsE
GKD17_RS14395	COG0527	aspartate kinase activity
GKD17_RS14400	COG0019	diaminopimelate decarboxylase activity
GKD17_RS14425	COG2431	L-lysine efflux transmembrane transporter activity
GKD17_RS14435	COG0436	Aminotransferase
GKD17_RS14450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKD17_RS14455	COG0167	dihydroorotate dehydrogenase activity
GKD17_RS14505	COG1027	Aspartate ammonia-lyase
GKD17_RS14510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKD17_RS14530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GKD17_RS14540	COG4657	Part of a membrane complex involved in electron transport
GKD17_RS14545	COG4660	Part of a membrane complex involved in electron transport
GKD17_RS14550	COG4659	FMN binding
GKD17_RS14555	COG4658	electron transport chain
GKD17_RS14560	COG4656	Part of a membrane complex involved in electron transport
GKD17_RS14575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKD17_RS14590	COG0076	glutamate decarboxylase activity
GKD17_RS14595	COG2066	Belongs to the glutaminase family
GKD17_RS14600	COG3142	Participates in the control of copper homeostasis
GKD17_RS14615	COG0531	amino acid
GKD17_RS14620	COG5002	protein histidine kinase activity
GKD17_RS14625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GKD17_RS14630	COG0481	GTPase activity
GKD17_RS14650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKD17_RS14655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GKD17_RS14735	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GKD17_RS14740	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS14745	COG0110	maltose O-acetyltransferase activity
GKD17_RS14775	COG1442	glycosyl transferase family 8
GKD17_RS14805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GKD17_RS14855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GKD17_RS14860	COG0581	inorganic phosphate transmembrane transporter activity
GKD17_RS14865	COG0573	inorganic phosphate transmembrane transporter activity
GKD17_RS14870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GKD17_RS14875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKD17_RS14890	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKD17_RS14895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKD17_RS14900	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GKD17_RS14910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKD17_RS14935	COG2115	Belongs to the xylose isomerase family
GKD17_RS14950	COG0745	RESPONSE REGULATOR receiver
GKD17_RS14950	COG2205	protein histidine kinase activity
GKD17_RS14950	COG3292	Two component regulator propeller
GKD17_RS14955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GKD17_RS14975	COG1215	transferase activity, transferring glycosyl groups
GKD17_RS15000	COG1216	Glycosyl transferase, family 2
GKD17_RS15005	COG1216	Glycosyl transferase, family 2
GKD17_RS15025	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS15035	COG1215	transferase activity, transferring glycosyl groups
GKD17_RS15055	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS15065	COG1216	Glycosyl transferase, family 2
GKD17_RS15065	COG1442	glycosyl transferase family 8
GKD17_RS15070	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS15075	COG0463	Glycosyl transferase, family 2
GKD17_RS15080	COG0745	RESPONSE REGULATOR receiver
GKD17_RS15085	COG0784	Response regulator, receiver
GKD17_RS15085	COG2205	protein histidine kinase activity
GKD17_RS15100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKD17_RS15105	COG0352	thiamine-phosphate diphosphorylase activity
GKD17_RS15105	COG0351	phosphomethylpyrimidine kinase
GKD17_RS15110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GKD17_RS15120	COG0366	Alpha amylase catalytic
GKD17_RS15135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKD17_RS15140	COG0071	Belongs to the small heat shock protein (HSP20) family
GKD17_RS15155	COG0505	Belongs to the CarA family
GKD17_RS15165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GKD17_RS15170	COG0069	glutamate synthase activity
GKD17_RS15170	COG0070	glutamate synthase
GKD17_RS15170	COG0067	glutamate synthase
GKD17_RS15180	COG0367	asparagine synthase
GKD17_RS15245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKD17_RS15280	COG0110	maltose O-acetyltransferase activity
GKD17_RS15290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKD17_RS15325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKD17_RS15335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKD17_RS15340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GKD17_RS15345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKD17_RS15350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKD17_RS15360	COG0242	peptide deformylase activity
GKD17_RS15365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKD17_RS15410	COG0823	Involved in the tonB-independent uptake of proteins
GKD17_RS15410	COG1506	peptidase
GKD17_RS15410	COG4946	Tricorn protease homolog
GKD17_RS15415	COG0477	Major facilitator Superfamily
GKD17_RS15415	COG2814	Major facilitator Superfamily
GKD17_RS15440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS15470	COG0133	tryptophan synthase activity
GKD17_RS15475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKD17_RS15480	COG0512	Glutamine amidotransferase of anthranilate synthase
GKD17_RS15485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKD17_RS15490	COG0134	indole-3-glycerol-phosphate synthase activity
GKD17_RS15495	COG0135	phosphoribosylanthranilate isomerase activity
GKD17_RS15500	COG0159	tryptophan synthase activity
GKD17_RS15505	COG0252	asparaginase activity
GKD17_RS15510	COG0745	RESPONSE REGULATOR receiver
GKD17_RS15515	COG5002	protein histidine kinase activity
GKD17_RS15530	COG0629	single-stranded DNA binding
GKD17_RS15540	COG0776	regulation of translation
GKD17_RS15545	COG1530	ribonuclease E activity
GKD17_RS15555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GKD17_RS15565	COG0784	Response regulator, receiver
GKD17_RS15565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS15565	COG2198	Histidine kinase
GKD17_RS15565	COG2205	protein histidine kinase activity
GKD17_RS15580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GKD17_RS15590	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS15635	COG0582	viral genome integration into host DNA
GKD17_RS15645	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GKD17_RS15650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GKD17_RS15655	COG0166	Belongs to the GPI family
GKD17_RS15660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GKD17_RS15670	COG0702	epimerase
GKD17_RS15675	COG4771	TonB-dependent receptor
GKD17_RS15690	COG1940	carbohydrate kinase activity
GKD17_RS15705	COG2271	Major facilitator Superfamily
GKD17_RS15710	COG0363	glucosamine-6-phosphate deaminase activity
GKD17_RS15715	COG0363	glucosamine-6-phosphate deaminase activity
GKD17_RS15725	COG1917	Cupin 2, conserved barrel domain protein
GKD17_RS15725	COG4977	sequence-specific DNA binding
GKD17_RS15730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS15770	COG1131	(ABC) transporter
GKD17_RS15790	COG0745	RESPONSE REGULATOR receiver
GKD17_RS15800	COG3250	beta-galactosidase activity
GKD17_RS15810	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS15820	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS15840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS15855	COG1629	transport
GKD17_RS15855	COG4206	TonB-dependent receptor
GKD17_RS15865	COG2502	aspartate--ammonia ligase
GKD17_RS15870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKD17_RS15885	COG3876	Protein conserved in bacteria
GKD17_RS15900	COG1132	(ABC) transporter
GKD17_RS15920	COG0732	type I restriction modification DNA specificity domain
GKD17_RS15940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GKD17_RS16005	COG1349	DNA-binding transcription factor activity
GKD17_RS16010	COG0110	maltose O-acetyltransferase activity
GKD17_RS16055	COG4974	Belongs to the 'phage' integrase family
GKD17_RS16110	COG2204	response regulator
GKD17_RS16115	COG5002	protein histidine kinase activity
GKD17_RS16115	COG2198	Histidine kinase
GKD17_RS16115	COG0784	Response regulator, receiver
GKD17_RS16120	COG0805	protein transport
GKD17_RS16125	COG1472	Belongs to the glycosyl hydrolase 3 family
GKD17_RS16135	COG2942	2-epimerase
GKD17_RS16140	COG2211	Major facilitator Superfamily
GKD17_RS16145	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GKD17_RS16150	COG4124	Belongs to the glycosyl hydrolase 26 family
GKD17_RS16160	COG0702	epimerase
GKD17_RS16165	COG4771	TonB-dependent receptor
GKD17_RS16170	COG3458	cephalosporin-C deacetylase activity
GKD17_RS16180	COG2205	protein histidine kinase activity
GKD17_RS16180	COG3292	Two component regulator propeller
GKD17_RS16180	COG3292	Two component regulator propeller
GKD17_RS16180	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16180	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16180	COG2205	protein histidine kinase activity
GKD17_RS16195	COG0860	N-Acetylmuramoyl-L-alanine amidase
GKD17_RS16205	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKD17_RS16210	COG0778	Nitroreductase
GKD17_RS16225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKD17_RS16240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKD17_RS16245	COG0318	PFAM AMP-dependent synthetase and ligase
GKD17_RS16255	COG0359	binds to the 23S rRNA
GKD17_RS16260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKD17_RS16265	COG0360	Binds together with S18 to 16S ribosomal RNA
GKD17_RS16290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKD17_RS16295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GKD17_RS16345	COG3661	Belongs to the glycosyl hydrolase 67 family
GKD17_RS16355	COG3507	Belongs to the glycosyl hydrolase 43 family
GKD17_RS16360	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16360	COG3292	Two component regulator propeller
GKD17_RS16360	COG2205	protein histidine kinase activity
GKD17_RS16370	COG1629	transport
GKD17_RS16370	COG4206	TonB-dependent receptor
GKD17_RS16375	COG3507	Belongs to the glycosyl hydrolase 43 family
GKD17_RS16390	COG2211	Major facilitator Superfamily
GKD17_RS16400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKD17_RS16410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GKD17_RS16415	COG0658	competence protein
GKD17_RS16415	COG2333	competence protein COMEC
GKD17_RS16420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GKD17_RS16440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKD17_RS16450	COG0009	L-threonylcarbamoyladenylate synthase
GKD17_RS16455	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKD17_RS16490	COG0681	Belongs to the peptidase S26 family
GKD17_RS16520	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16530	COG3292	Two component regulator propeller
GKD17_RS16530	COG2205	protein histidine kinase activity
GKD17_RS16530	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKD17_RS16565	COG1280	lysine exporter protein (LysE YggA)
GKD17_RS16570	COG0047	phosphoribosylformylglycinamidine synthase activity
GKD17_RS16570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKD17_RS16575	COG2205	protein histidine kinase activity
GKD17_RS16575	COG3292	Two component regulator propeller
GKD17_RS16575	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16580	COG2059	Chromate
GKD17_RS16595	COG1501	Belongs to the glycosyl hydrolase 31 family
GKD17_RS16600	COG1649	PFAM Uncharacterised BCR, COG1649
GKD17_RS16615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS16630	COG1966	Carbon starvation protein
GKD17_RS16640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GKD17_RS16645	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKD17_RS16650	COG0284	orotidine-5'-phosphate decarboxylase activity
GKD17_RS16655	COG1078	dGTPase activity
GKD17_RS16660	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKD17_RS16665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GKD17_RS16665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKD17_RS16670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKD17_RS16680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKD17_RS16700	COG0386	Belongs to the glutathione peroxidase family
GKD17_RS16710	COG1629	transport
GKD17_RS16710	COG4206	TonB-dependent receptor
GKD17_RS16720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS16730	COG4948	Mandelate Racemase Muconate Lactonizing
GKD17_RS16835	COG1629	transport
GKD17_RS16835	COG4206	TonB-dependent receptor
GKD17_RS16870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS16900	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKD17_RS16900	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKD17_RS16905	COG0436	Aminotransferase
GKD17_RS16915	COG1472	Belongs to the glycosyl hydrolase 3 family
GKD17_RS16920	COG0737	Belongs to the 5'-nucleotidase family
GKD17_RS16925	COG0737	Belongs to the 5'-nucleotidase family
GKD17_RS16930	COG0335	large ribosomal subunit rRNA binding
GKD17_RS16940	COG0745	RESPONSE REGULATOR receiver
GKD17_RS16940	COG3292	Two component regulator propeller
GKD17_RS16940	COG2205	protein histidine kinase activity
GKD17_RS16945	COG3254	rhamnose metabolic process
GKD17_RS16950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GKD17_RS16955	COG3401	FG-GAP repeat protein
GKD17_RS16985	COG0702	epimerase
GKD17_RS16990	COG4771	TonB-dependent receptor
GKD17_RS17010	COG2755	lipolytic protein G-D-S-L family
GKD17_RS17015	COG3401	FG-GAP repeat protein
GKD17_RS17020	COG3250	beta-galactosidase activity
GKD17_RS17030	COG3119	arylsulfatase activity
GKD17_RS17045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS17050	COG1629	transport
GKD17_RS17050	COG4206	TonB-dependent receptor
GKD17_RS17065	COG1629	transport
GKD17_RS17065	COG4206	TonB-dependent receptor
GKD17_RS17075	COG4771	TonB-dependent receptor
GKD17_RS17085	COG4771	TonB-dependent receptor
GKD17_RS17110	COG3401	FG-GAP repeat protein
GKD17_RS17135	COG3250	beta-galactosidase activity
GKD17_RS17140	COG2755	lipolytic protein G-D-S-L family
GKD17_RS17180	COG3254	rhamnose metabolic process
GKD17_RS17185	COG1940	carbohydrate kinase activity
GKD17_RS17190	COG1136	(ABC) transporter
GKD17_RS17195	COG0577	efflux transmembrane transporter activity
GKD17_RS17195	COG1136	(ABC) transporter
GKD17_RS17200	COG1136	(ABC) transporter
GKD17_RS17200	COG0577	efflux transmembrane transporter activity
GKD17_RS17220	COG2996	Protein conserved in bacteria
GKD17_RS17225	COG1979	alcohol dehydrogenase
GKD17_RS17235	COG1136	(ABC) transporter
GKD17_RS17240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GKD17_RS17245	COG0589	response to stress
GKD17_RS17245	COG0475	glutathione-regulated potassium exporter activity
GKD17_RS17250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKD17_RS17260	COG0423	glycine-tRNA ligase activity
GKD17_RS17300	COG0702	epimerase
GKD17_RS17305	COG1629	transport
GKD17_RS17315	COG2207	Transcriptional regulator
GKD17_RS17330	COG0738	Major facilitator superfamily
GKD17_RS17335	COG1063	alcohol dehydrogenase
GKD17_RS17340	COG2095	MarC family integral membrane protein
GKD17_RS17375	COG1696	Membrane protein involved in D-alanine export
GKD17_RS17400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS17430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS17440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GKD17_RS17485	COG3969	phosphoadenosine phosphosulfate
GKD17_RS17490	COG1475	DNA binding
GKD17_RS17500	COG0039	L-malate dehydrogenase activity
GKD17_RS17515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS17545	COG0489	protein tyrosine kinase activity
GKD17_RS17560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GKD17_RS17565	COG1722	exodeoxyribonuclease VII activity
GKD17_RS17570	COG1570	exodeoxyribonuclease VII activity
GKD17_RS17580	COG0534	Mate efflux family protein
GKD17_RS17715	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GKD17_RS17725	COG1088	dTDP-glucose 4,6-dehydratase activity
GKD17_RS17730	COG1629	transport
GKD17_RS17740	COG3250	beta-galactosidase activity
GKD17_RS17745	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GKD17_RS17745	COG3408	Glycogen debranching enzyme
GKD17_RS17750	COG0702	epimerase
GKD17_RS17755	COG4771	TonB-dependent receptor
GKD17_RS17770	COG0488	(ABC) transporter
GKD17_RS17775	COG2985	domain, Protein
GKD17_RS17775	COG0569	domain protein
GKD17_RS17780	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GKD17_RS17785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GKD17_RS17785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GKD17_RS17795	COG1629	transport
GKD17_RS17805	COG1629	transport
GKD17_RS17805	COG4206	TonB-dependent receptor
GKD17_RS17810	COG2205	protein histidine kinase activity
GKD17_RS17815	COG0668	transmembrane transport
GKD17_RS17840	COG0681	Belongs to the peptidase S26 family
GKD17_RS17855	COG2086	electron transfer activity
GKD17_RS17860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GKD17_RS17880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKD17_RS17890	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GKD17_RS17900	COG4804	nuclease activity
GKD17_RS17915	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GKD17_RS17925	COG1228	amidohydrolase
GKD17_RS17930	COG3404	Formiminotransferase-cyclodeaminase
GKD17_RS17935	COG2986	histidine ammonia-lyase
GKD17_RS17940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GKD17_RS17950	COG0693	protein deglycase activity
GKD17_RS17970	COG0673	inositol 2-dehydrogenase activity
GKD17_RS17975	COG0288	reversible hydration of carbon dioxide
GKD17_RS17995	COG0459	protein refolding
GKD17_RS18000	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKD17_RS18010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GKD17_RS18020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKD17_RS18025	COG0124	histidyl-tRNA synthetase
GKD17_RS18030	COG1879	ABC-type sugar transport system periplasmic component
GKD17_RS18045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GKD17_RS18050	COG3958	Transketolase
GKD17_RS18055	COG3959	Transketolase, thiamine diphosphate binding domain
GKD17_RS18060	COG1349	DNA-binding transcription factor activity
GKD17_RS18065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKD17_RS18065	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GKD17_RS18075	COG3292	Two component regulator propeller
GKD17_RS18075	COG2205	protein histidine kinase activity
GKD17_RS18075	COG0745	RESPONSE REGULATOR receiver
GKD17_RS18075	COG3292	Two component regulator propeller
GKD17_RS18075	COG2205	protein histidine kinase activity
GKD17_RS18075	COG0745	RESPONSE REGULATOR receiver
GKD17_RS18085	COG1629	transport
GKD17_RS18155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKD17_RS18165	COG0534	Mate efflux family protein
GKD17_RS18170	COG2205	protein histidine kinase activity
GKD17_RS18170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS18170	COG2198	Histidine kinase
GKD17_RS18170	COG0784	Response regulator, receiver
GKD17_RS18175	COG2204	response regulator
GKD17_RS18185	COG0564	pseudouridine synthase activity
GKD17_RS18190	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS18205	COG3250	beta-galactosidase activity
GKD17_RS18225	COG1629	transport
GKD17_RS18225	COG4206	TonB-dependent receptor
GKD17_RS18230	COG0513	Belongs to the DEAD box helicase family
GKD17_RS18250	COG0482	sulfurtransferase activity
GKD17_RS18255	COG2197	response regulator
GKD17_RS18285	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GKD17_RS18300	COG3022	response to hydroperoxide
GKD17_RS18305	COG2885	chlorophyll binding
GKD17_RS18315	COG2895	sulfate adenylyltransferase (ATP) activity
GKD17_RS18320	COG0175	sulfate reduction
GKD17_RS18325	COG0529	Catalyzes the synthesis of activated sulfate
GKD17_RS18330	COG3273	potassium ion transport
GKD17_RS18330	COG0471	metal ion transport
GKD17_RS18335	COG1218	3'(2'),5'-bisphosphate nucleotidase
GKD17_RS18345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKD17_RS18375	COG0517	IMP dehydrogenase activity
GKD17_RS18375	COG0516	GMP reductase activity
GKD17_RS18385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKD17_RS18390	COG0740	serine-type endopeptidase activity
GKD17_RS18395	COG0544	peptidyl-prolyl cis-trans isomerase activity
GKD17_RS18400	COG0724	RNA recognition motif
GKD17_RS18410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GKD17_RS18415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKD17_RS18420	COG1160	GTP binding
GKD17_RS18425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKD17_RS18430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKD17_RS18485	COG0039	L-malate dehydrogenase activity
GKD17_RS18490	COG0358	DNA primase activity
GKD17_RS18495	COG0302	gtp cyclohydrolase
GKD17_RS18515	COG0739	heme binding
GKD17_RS18520	COG0105	UTP biosynthetic process
GKD17_RS18525	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKD17_RS18530	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GKD17_RS18545	COG0848	biopolymer transport protein
GKD17_RS18550	COG0811	peptide transport
GKD17_RS18555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GKD17_RS18560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKD17_RS18590	COG0420	3'-5' exonuclease activity
GKD17_RS18600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS18605	COG4206	TonB-dependent receptor
GKD17_RS18605	COG1629	transport
GKD17_RS18610	COG4977	sequence-specific DNA binding
GKD17_RS18630	COG3408	Glycogen debranching enzyme
GKD17_RS18635	COG0702	epimerase
GKD17_RS18640	COG4771	TonB-dependent receptor
GKD17_RS18655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GKD17_RS18660	COG4771	TonB-dependent receptor
GKD17_RS18665	COG0702	epimerase
GKD17_RS18680	COG3507	Belongs to the glycosyl hydrolase 43 family
GKD17_RS18690	COG4771	TonB-dependent receptor
GKD17_RS18700	COG4206	TonB-dependent receptor
GKD17_RS18700	COG1629	transport
GKD17_RS18705	COG3292	Two component regulator propeller
GKD17_RS18705	COG2205	protein histidine kinase activity
GKD17_RS18705	COG0745	RESPONSE REGULATOR receiver
GKD17_RS18725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GKD17_RS18730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKD17_RS18735	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKD17_RS18750	COG1346	cytolysis
GKD17_RS18760	COG0280	phosphate acetyltransferase
GKD17_RS18765	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKD17_RS18770	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GKD17_RS18775	COG2151	metal-sulfur cluster biosynthetic enzyme
GKD17_RS18780	COG2003	Belongs to the UPF0758 family
GKD17_RS18785	COG1216	Glycosyl transferase, family 2
GKD17_RS18785	COG0463	Glycosyl transferase, family 2
GKD17_RS18790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKD17_RS18795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GKD17_RS18800	COG0641	radical SAM
GKD17_RS18830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GKD17_RS18835	COG3119	arylsulfatase activity
GKD17_RS18840	COG0702	epimerase
GKD17_RS18845	COG4771	TonB-dependent receptor
GKD17_RS18850	COG2755	lipolytic protein G-D-S-L family
GKD17_RS18850	COG0657	acetylesterase activity
GKD17_RS18855	COG3292	Two component regulator propeller
GKD17_RS18855	COG2205	protein histidine kinase activity
GKD17_RS18855	COG0745	RESPONSE REGULATOR receiver
GKD17_RS18875	COG0564	pseudouridine synthase activity
GKD17_RS18880	COG1181	Belongs to the D-alanine--D-alanine ligase family
GKD17_RS18900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKD17_RS18905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKD17_RS18910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKD17_RS18915	COG0561	phosphatase activity
GKD17_RS18940	COG1629	transport
GKD17_RS18940	COG4206	TonB-dependent receptor
GKD17_RS18950	COG4771	TonB-dependent receptor
GKD17_RS18965	COG1629	transport
GKD17_RS18965	COG4206	TonB-dependent receptor
GKD17_RS18985	COG4206	TonB-dependent receptor
GKD17_RS18985	COG1629	transport
GKD17_RS19000	COG1629	transport
GKD17_RS19000	COG4206	TonB-dependent receptor
GKD17_RS19010	COG1629	transport
GKD17_RS19010	COG4206	TonB-dependent receptor
GKD17_RS19025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GKD17_RS19030	COG1396	sequence-specific DNA binding
GKD17_RS19030	COG1917	Cupin 2, conserved barrel domain protein
GKD17_RS19045	COG0348	domain, Protein
GKD17_RS19050	COG0667	Aldo Keto reductase
GKD17_RS19055	COG1368	sulfuric ester hydrolase activity
GKD17_RS19060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKD17_RS19065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GKD17_RS19070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GKD17_RS19075	COG0137	argininosuccinate synthase activity
GKD17_RS19085	COG1438	arginine binding
GKD17_RS19090	COG1070	Carbohydrate kinase
GKD17_RS19095	COG4806	L-rhamnose isomerase
GKD17_RS19105	COG0235	Class ii aldolase
GKD17_RS19120	COG0702	epimerase
GKD17_RS19125	COG4206	TonB-dependent receptor
GKD17_RS19125	COG1629	transport
GKD17_RS19130	COG0745	RESPONSE REGULATOR receiver
GKD17_RS19130	COG3292	Two component regulator propeller
GKD17_RS19130	COG2205	protein histidine kinase activity
GKD17_RS19140	COG1388	LysM domain
GKD17_RS19140	COG0741	lytic transglycosylase activity
GKD17_RS19145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GKD17_RS19150	COG3250	beta-galactosidase activity
GKD17_RS19170	COG0673	inositol 2-dehydrogenase activity
GKD17_RS19185	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS19190	COG0656	L-ascorbic acid biosynthetic process
GKD17_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS19200	COG2249	NAD(P)H dehydrogenase (quinone) activity
GKD17_RS19205	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GKD17_RS19215	COG1082	Xylose isomerase domain protein TIM barrel
GKD17_RS19235	COG4771	TonB-dependent receptor
GKD17_RS19240	COG3537	Alpha-1,2-mannosidase
GKD17_RS19270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GKD17_RS19275	COG0542	response to heat
GKD17_RS19280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GKD17_RS19290	COG0534	Mate efflux family protein
GKD17_RS19300	COG2197	response regulator
GKD17_RS19305	COG3345	alpha-galactosidase
GKD17_RS19395	COG0551	DNA topoisomerase type I activity
GKD17_RS19395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKD17_RS19415	COG0784	Response regulator, receiver
GKD17_RS19415	COG2205	protein histidine kinase activity
GKD17_RS19425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKD17_RS19490	COG0542	response to heat
GKD17_RS19645	COG1192	Involved in chromosome partitioning
GKD17_RS19825	COG0561	phosphatase activity
GKD17_RS19830	COG4771	TonB-dependent receptor
GKD17_RS19875	COG0702	epimerase
GKD17_RS19880	COG1629	transport
GKD17_RS19890	COG2205	protein histidine kinase activity
GKD17_RS19890	COG0745	RESPONSE REGULATOR receiver
GKD17_RS19890	COG3292	Two component regulator propeller
GKD17_RS19890	COG3292	Two component regulator propeller
GKD17_RS19890	COG2205	protein histidine kinase activity
GKD17_RS19890	COG0745	RESPONSE REGULATOR receiver
GKD17_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
GKD17_RS19900	COG0457	Tetratricopeptide repeat
GKD17_RS19905	COG2814	Major facilitator Superfamily
GKD17_RS19915	COG3537	Alpha-1,2-mannosidase
GKD17_RS19920	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GKD17_RS19920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKD17_RS19970	COG2873	o-acetylhomoserine
GKD17_RS19985	COG1595	DNA-templated transcription, initiation
GKD17_RS20020	COG0203	ribosomal protein L17
GKD17_RS20025	COG0202	RNA polymerase activity
GKD17_RS20030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKD17_RS20035	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKD17_RS20040	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKD17_RS20045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GKD17_RS20050	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKD17_RS20065	COG0200	Binds to the 23S rRNA
GKD17_RS20070	COG1841	ribosomal large subunit assembly
GKD17_RS20075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKD17_RS20080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKD17_RS20085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKD17_RS20090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKD17_RS20095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKD17_RS20100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKD17_RS20105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKD17_RS20110	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKD17_RS20115	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKD17_RS20120	COG0255	Belongs to the universal ribosomal protein uL29 family
GKD17_RS20125	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKD17_RS20130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKD17_RS20135	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKD17_RS20140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKD17_RS20145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKD17_RS20150	COG0089	rRNA binding
GKD17_RS20155	COG0088	Forms part of the polypeptide exit tunnel
GKD17_RS20160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKD17_RS20165	COG0051	transcription antitermination factor activity, RNA binding
GKD17_RS20170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKD17_RS20175	COG0049	tRNA binding
GKD17_RS20180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKD17_RS20190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKD17_RS20195	COG0085	RNA polymerase activity
GKD17_RS20200	COG0222	ribosome binding
GKD17_RS20205	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKD17_RS20210	COG0081	regulation of translation
GKD17_RS20215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKD17_RS20235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKD17_RS20265	COG4974	Belongs to the 'phage' integrase family
GKD17_RS20270	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GKD17_RS20280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GKD17_RS20295	COG0745	RESPONSE REGULATOR receiver
GKD17_RS20300	COG5002	protein histidine kinase activity
GKD17_RS20310	COG0793	Belongs to the peptidase S41A family
GKD17_RS20315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GKD17_RS20365	COG1629	transport
GKD17_RS20365	COG4206	TonB-dependent receptor
GKD17_RS20370	COG0702	epimerase
GKD17_RS20375	COG0584	glycerophosphoryl diester phosphodiesterase
GKD17_RS20380	COG3537	Alpha-1,2-mannosidase
GKD17_RS20400	COG3292	Two component regulator propeller
GKD17_RS20400	COG0745	RESPONSE REGULATOR receiver
GKD17_RS20400	COG2205	protein histidine kinase activity
GKD17_RS20410	COG4771	TonB-dependent receptor
GKD17_RS20415	COG0702	epimerase
GKD17_RS20435	COG3634	alkyl hydroperoxide reductase activity
GKD17_RS20445	COG0148	phosphopyruvate hydratase activity
GKD17_RS20470	COG3250	beta-galactosidase activity
GKD17_RS20485	COG1629	transport
GKD17_RS20485	COG4206	TonB-dependent receptor
GKD17_RS20490	COG3292	Two component regulator propeller
GKD17_RS20490	COG2205	protein histidine kinase activity
GKD17_RS20490	COG0745	RESPONSE REGULATOR receiver
GKD17_RS20530	COG3250	beta-galactosidase activity
GKD17_RS20535	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GKD17_RS20540	COG4771	TonB-dependent receptor
GKD17_RS20545	COG2205	protein histidine kinase activity
GKD17_RS20545	COG0745	RESPONSE REGULATOR receiver
GKD17_RS20545	COG3292	Two component regulator propeller
GKD17_RS20550	COG0519	Catalyzes the synthesis of GMP from XMP
GKD17_RS20570	COG0667	Aldo Keto reductase
GKD17_RS20575	COG0165	Argininosuccinate lyase
GKD17_RS20585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKD17_RS20610	COG2890	protein-(glutamine-N5) methyltransferase activity
GKD17_RS20615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKD17_RS20615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GKD17_RS20625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKD17_RS20645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GKD17_RS20660	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKD17_RS20675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GKD17_RS20680	COG4974	Belongs to the 'phage' integrase family
GKD17_RS20720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKD17_RS20720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKD17_RS20745	COG3475	LICD family
GKD17_RS20760	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS20775	COG4974	Belongs to the 'phage' integrase family
GKD17_RS20810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKD17_RS20810	COG0551	DNA topoisomerase type I activity
GKD17_RS20975	COG0739	heme binding
GKD17_RS20975	COG1196	nuclear chromosome segregation
GKD17_RS20975	COG0741	lytic transglycosylase activity
GKD17_RS21005	COG3177	Filamentation induced by cAMP protein fic
GKD17_RS21025	COG1192	Involved in chromosome partitioning
GKD17_RS21120	COG0784	Response regulator, receiver
GKD17_RS21120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GKD17_RS21120	COG2198	Histidine kinase
GKD17_RS21120	COG2205	protein histidine kinase activity
GKD17_RS21240	COG0358	DNA primase activity
GKD17_RS21305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKD17_RS21310	COG1854	S-ribosylhomocysteine lyase activity
GKD17_RS21315	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKD17_RS21370	COG0745	RESPONSE REGULATOR receiver
GKD17_RS21370	COG3292	Two component regulator propeller
GKD17_RS21370	COG2205	protein histidine kinase activity
GKD17_RS21385	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GKD17_RS21390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKD17_RS21395	COG1013	pyruvate-flavodoxin oxidoreductase activity
GKD17_RS21400	COG0674	pyruvate-flavodoxin oxidoreductase activity
GKD17_RS21400	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GKD17_RS21415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GKD17_RS21425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GKD17_RS21430	COG0339	signal peptide processing
GKD17_RS21450	COG0776	regulation of translation
GKD17_RS21455	COG3250	beta-galactosidase activity
GKD17_RS21465	COG0482	sulfurtransferase activity
GKD17_RS21470	COG3119	arylsulfatase activity
GKD17_RS21480	COG3507	Belongs to the glycosyl hydrolase 43 family
GKD17_RS21485	COG3292	Two component regulator propeller
GKD17_RS21485	COG2205	protein histidine kinase activity
GKD17_RS21485	COG0745	RESPONSE REGULATOR receiver
GKD17_RS21490	COG1082	Xylose isomerase domain protein TIM barrel
GKD17_RS21495	COG1629	transport
GKD17_RS21495	COG4206	TonB-dependent receptor
GKD17_RS21515	COG0215	cysteine-tRNA ligase activity
GKD17_RS21530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKD17_RS21535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKD17_RS21570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKD17_RS21600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GKD17_RS21675	COG0205	6-phosphofructokinase activity
GKD17_RS21680	COG3292	Two component regulator propeller
GKD17_RS21680	COG2205	protein histidine kinase activity
GKD17_RS21680	COG0745	RESPONSE REGULATOR receiver
GKD17_RS21685	COG4206	TonB-dependent receptor
GKD17_RS21685	COG1629	transport
GKD17_RS21700	COG3119	arylsulfatase activity
GKD17_RS21720	COG0571	ribonuclease III activity
GKD17_RS21725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GKD17_RS21730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKD17_RS21735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKD17_RS21745	COG4206	TonB-dependent receptor
GKD17_RS21745	COG1629	transport
GKD17_RS21800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GKD17_RS21815	COG0562	UDP-galactopyranose mutase
GKD17_RS21845	COG0438	transferase activity, transferring glycosyl groups
GKD17_RS21855	COG1132	(ABC) transporter
GKD17_RS21865	COG1215	transferase activity, transferring glycosyl groups
GKD17_RS21875	COG0463	Glycosyl transferase, family 2
GKD17_RS21885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GKD17_RS21895	COG0328	RNA-DNA hybrid ribonuclease activity
GKD17_RS21895	COG3341	Caulimovirus viroplasmin
GKD17_RS21900	COG0018	arginyl-trna synthetase
GKD17_RS21905	COG1629	transport
GKD17_RS21915	COG0653	protein targeting
GKD17_RS21950	COG0826	peptidase U32
GKD17_RS21955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKD17_RS21975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKD17_RS21980	COG0557	exoribonuclease II activity
GKD17_RS21985	COG1045	serine acetyltransferase
GKD17_RS21990	COG4251	negative regulation of phosphorylation
GKD17_RS22000	COG0783	Belongs to the Dps family
GKD17_RS22050	COG0484	heat shock protein binding
GKD17_RS22080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GKD17_RS22335	COG0116	Belongs to the methyltransferase superfamily
GKD17_RS22340	COG0823	Involved in the tonB-independent uptake of proteins
GKD17_RS22340	COG1506	peptidase
GKD17_RS22390	COG0726	polysaccharide deacetylase
GKD17_RS22405	COG0561	phosphatase activity
GKD17_RS22410	COG4771	TonB-dependent receptor
GKD17_RS22415	COG4677	pectinesterase activity
GKD17_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
GKD17_RS22425	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GKD17_RS22430	COG2027	D-alanyl-D-alanine carboxypeptidase
GKD17_RS22455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GKD17_RS22485	COG4948	Mandelate Racemase Muconate Lactonizing
GKD17_RS22495	COG0702	epimerase
GKD17_RS22500	COG4206	TonB-dependent receptor
GKD17_RS22500	COG1629	transport
GKD17_RS22530	COG1629	transport
GKD17_RS22545	COG0745	RESPONSE REGULATOR receiver
GKD17_RS22545	COG2205	protein histidine kinase activity
GKD17_RS22545	COG3292	Two component regulator propeller
GKD17_RS22550	COG1592	Rubrerythrin
GKD17_RS22560	COG0659	secondary active sulfate transmembrane transporter activity
GKD17_RS22575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKD17_RS22625	COG5002	protein histidine kinase activity
GKD17_RS22635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKD17_RS22635	COG0731	radical SAM domain protein
GKD17_RS22655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GKD17_RS22660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKD17_RS22670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GKD17_RS22675	COG0495	leucyl-tRNA aminoacylation
GKD17_RS22680	COG3292	Two component regulator propeller
GKD17_RS22680	COG2205	protein histidine kinase activity
GKD17_RS22680	COG0745	RESPONSE REGULATOR receiver
GKD17_RS22680	COG3292	Two component regulator propeller
GKD17_RS22680	COG2205	protein histidine kinase activity
GKD17_RS22680	COG0745	RESPONSE REGULATOR receiver
GKD17_RS22685	COG3250	beta-galactosidase activity
GKD17_RS22690	COG1629	transport
GKD17_RS22695	COG0702	epimerase
GKD17_RS22700	COG0793	Belongs to the peptidase S41A family
GKD17_RS22700	COG4946	Tricorn protease homolog
GKD17_RS22705	COG1595	DNA-templated transcription, initiation
GKD17_RS22715	COG1629	transport
GKD17_RS22715	COG4206	TonB-dependent receptor
GKD17_RS22725	COG3119	arylsulfatase activity
GKD17_RS22730	COG3119	arylsulfatase activity
GKD17_RS22740	COG1472	Belongs to the glycosyl hydrolase 3 family
GKD17_RS22745	COG0427	acetyl-CoA hydrolase
GKD17_RS22755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GKD17_RS22760	COG0545	Peptidyl-prolyl cis-trans isomerase
GKD17_RS22765	COG1983	PspC domain protein
GKD17_RS22775	COG2177	Part of the ABC transporter FtsEX involved in
GKD17_RS22785	COG1968	undecaprenyl-diphosphatase activity
GKD17_RS22790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKD17_RS22795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKD17_RS22800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GKD17_RS22850	COG2814	Major facilitator Superfamily
GKD17_RS22855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKD17_RS22860	COG1611	Belongs to the LOG family
GKD17_RS22875	COG0594	ribonuclease P activity
GKD17_RS22880	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GKD17_RS22890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKD17_RS22950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKD17_RS22995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKD17_RS23005	COG0012	GTP binding
GKD17_RS23015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKD17_RS23015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKD17_RS23020	COG0142	geranyltranstransferase activity
GKD17_RS23030	COG1694	Mazg nucleotide pyrophosphohydrolase
GKD17_RS23035	COG1490	D-aminoacyl-tRNA deacylase activity
GKD17_RS23040	COG0322	excinuclease ABC activity
GKD17_RS23045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis