locus-tag	class	description
GN305_RS00005	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GN305_RS00010	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GN305_RS00015	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
GN305_RS00020	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
GN305_RS00025	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
GN305_RS00030	ENOG4105EAH	synthase
GN305_RS00035	ENOG4105C2M	dna polymerase I
GN305_RS00045	ENOG4105C3G	gtp-binding protein
GN305_RS00055	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GN305_RS00100	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GN305_RS00150	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GN305_RS00160	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GN305_RS00165	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GN305_RS00185	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GN305_RS00190	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GN305_RS00235	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GN305_RS00240	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GN305_RS00245	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GN305_RS00250	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GN305_RS00260	ENOG4107RJ9	Cell division protein FtsX
GN305_RS00270	ENOG41067S9	phage shock protein C, PspC
GN305_RS00275	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GN305_RS00280	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GN305_RS00290	ENOG4105CYC	Transferase
GN305_RS00305	ENOG41061MV	Arylsulfatase
GN305_RS00320	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS00330	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS00350	ENOG4105CNT	hydrolase family 2
GN305_RS00360	ENOG4105C8T	Leucyl-tRNA synthetase
GN305_RS00365	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
GN305_RS00375	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GN305_RS00405	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
GN305_RS00430	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN305_RS00440	ENOG4105BZU	Histidine kinase
GN305_RS00490	ENOG4106PHI	plasmid recombination enzyme
GN305_RS00500	ENOG4105VTR	Integrase
GN305_RS00505	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GN305_RS00520	ENOG4105CHH	sulfate transporter
GN305_RS00530	ENOG4108RAC	Rubrerythrin
GN305_RS00580	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS00615	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS00640	ENOG4108IYU	L-aspartate oxidase
GN305_RS00665	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
GN305_RS00670	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
GN305_RS00690	ENOG4105TT1	Ragb susd domain-containing protein
GN305_RS00695	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GN305_RS00705	ENOG4108ZJ4	polysaccharide deacetylase
GN305_RS00715	ENOG4105DIK	(ABC) transporter
GN305_RS00750	ENOG4105C12	Phosphoribosylglycinamide synthetase
GN305_RS00755	ENOG4105C5Z	peptidase
GN305_RS00770	ENOG4105C5Q	Transcriptional regulator
GN305_RS00775	ENOG4108RMU	ferritin dps family protein
GN305_RS00790	ENOG4105D7W	serine acetyltransferase
GN305_RS00795	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
GN305_RS00800	ENOG41076HS	cation diffusion facilitator family transporter
GN305_RS00820	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
GN305_RS00825	ENOG4105CFP	Peptidase U32
GN305_RS00840	ENOG4105C75	arginyL-tRNA synthetase
GN305_RS00845	ENOG4108B1Q	Ribonuclease
GN305_RS00855	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GN305_RS00885	ENOG4105BZ1	(ABC) transporter
GN305_RS00895	ENOG4107XU6	Glycosyl transferase (Group 1
GN305_RS00925	ENOG4105D5D	udp-galactopyranose mutase
GN305_RS00940	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GN305_RS01015	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS01025	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GN305_RS01030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GN305_RS01035	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GN305_RS01040	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GN305_RS01045	ENOG4105ENH	Sulfatase
GN305_RS01060	ENOG4105CBG	Sulfatase
GN305_RS01075	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS01085	ENOG4105CTQ	phosphohexokinase
GN305_RS01110	ENOG4105BZU	Histidine kinase
GN305_RS01160	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GN305_RS01190	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GN305_RS01225	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GN305_RS01230	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GN305_RS01235	ENOG4105CHR	reductase
GN305_RS01245	ENOG4105C8N	cysteinyl-tRNA synthetase
GN305_RS01265	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS01270	ENOG4105CGS	Alpha-glucosidase
GN305_RS01280	ENOG4106Z5D	Glycoside Hydrolase Family 43
GN305_RS01290	ENOG41061MV	Arylsulfatase
GN305_RS01295	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GN305_RS01305	ENOG4105CNT	hydrolase family 2
GN305_RS01310	ENOG4105K70	DNA-binding protein
GN305_RS01330	ENOG4105DGW	oligopeptidase A
GN305_RS01335	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GN305_RS01345	ENOG4105EXW	epimerase dehydratase
GN305_RS01350	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GN305_RS01360	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
GN305_RS01365	ENOG4105DQU	oxidoreductase, subunit beta
GN305_RS01370	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GN305_RS01375	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
GN305_RS01385	ENOG4105CI3	gtp-binding protein typa
GN305_RS01445	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GN305_RS01450	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
GN305_RS01455	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GN305_RS01470	ENOG4105CPK	Glycosyl transferase (Group 1
GN305_RS01485	ENOG4105KPE	licD family
GN305_RS01510	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GN305_RS01515	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GN305_RS01535	ENOG4105C0P	Mg chelatase subunit ChlI
GN305_RS01550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS01555	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GN305_RS01560	ENOG4105CA9	Pyruvate kinase
GN305_RS01570	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GN305_RS01580	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
GN305_RS01585	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GN305_RS01600	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GN305_RS01605	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GN305_RS01615	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GN305_RS01620	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GN305_RS01630	ENOG4105MJ2	Competence protein
GN305_RS01635	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GN305_RS01645	ENOG4105CH7	arginosuccinase
GN305_RS01650	ENOG4105CPC	Aldo Keto reductase
GN305_RS01670	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GN305_RS01790	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS01815	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS01835	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS01910	ENOG4105BZU	Histidine kinase
GN305_RS01950	ENOG4105C8J	)-transporter
GN305_RS01960	ENOG4105G6Z	alkaline phosphatase
GN305_RS01980	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GN305_RS02075	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS02115	ENOG4105D75	Capsular exopolysaccharide family
GN305_RS02125	ENOG4107QQG	Dehydrogenase
GN305_RS02145	ENOG4105C5E	polysaccharide biosynthesis protein
GN305_RS02160	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GN305_RS02190	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GN305_RS02195	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
GN305_RS02215	ENOG4105BZU	Histidine kinase
GN305_RS02250	ENOG4107QJE	Chromosome Partitioning Protein
GN305_RS02555	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GN305_RS02560	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
GN305_RS02565	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GN305_RS02650	ENOG4105CZV	ABC transporter
GN305_RS02670	ENOG4105UQX	Mate efflux family protein
GN305_RS02675	ENOG4107QTF	adenylosuccinate lyase
GN305_RS02680	ENOG4105FE9	pseudouridine synthase
GN305_RS02685	ENOG4105C5S	asparaginyl-tRNA synthetase
GN305_RS02705	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GN305_RS02710	ENOG4108UJD	30S ribosomal protein S9
GN305_RS02715	ENOG4105CE9	30S ribosomal protein S2
GN305_RS02720	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GN305_RS02730	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
GN305_RS02735	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
GN305_RS02740	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GN305_RS02745	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
GN305_RS02750	ENOG4107RN3	metallophosphoesterase
GN305_RS02760	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GN305_RS02770	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GN305_RS02780	ENOG41072GX	Peptidase M22 Glycoprotease
GN305_RS02790	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GN305_RS02795	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GN305_RS02800	ENOG4105DR5	peptidase
GN305_RS02805	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GN305_RS02810	ENOG4105DZP	Membrane-associated zinc metalloprotease
GN305_RS02820	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
GN305_RS02825	ENOG4108UT2	hemolysin iii
GN305_RS02830	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GN305_RS02840	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GN305_RS02845	ENOG4105DGA	Diaminopimelate dehydrogenase
GN305_RS02850	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GN305_RS02865	ENOG4108HKT	sucrose-6-phosphate hydrolase
GN305_RS02875	ENOG4105DE4	1-phosphofructokinase
GN305_RS02890	ENOG4105DZS	Phenylacetate-CoA ligase
GN305_RS02900	ENOG41081WG	50s ribosomal protein l31
GN305_RS02905	ENOG4105D2N	Aldolase
GN305_RS02950	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GN305_RS02960	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GN305_RS02965	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN305_RS02970	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
GN305_RS03005	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GN305_RS03050	ENOG4105DG6	mannose-6-phosphate isomerase
GN305_RS03055	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GN305_RS03070	ENOG4105CKI	cobalamin synthesis protein
GN305_RS03075	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS03110	ENOG4105BZU	Histidine kinase
GN305_RS03115	ENOG4105EWM	Histidine kinase
GN305_RS03125	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN305_RS03135	ENOG4105D65	subunit l
GN305_RS03150	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN305_RS03155	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GN305_RS03160	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN305_RS03165	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN305_RS03170	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GN305_RS03175	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GN305_RS03180	ENOG4105C1A	potassium transporter peripheral membrane
GN305_RS03185	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GN305_RS03195	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GN305_RS03210	ENOG4105CNT	hydrolase family 2
GN305_RS03235	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS03260	ENOG4105CNT	hydrolase family 2
GN305_RS03375	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS03390	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS03415	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS03500	ENOG4105BZU	Histidine kinase
GN305_RS03520	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS03555	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS03595	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS03625	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS03650	ENOG4105CNT	hydrolase family 2
GN305_RS03690	ENOG4105C26	Dehydrogenase
GN305_RS03715	ENOG4105DJB	Major Facilitator Superfamily
GN305_RS03725	ENOG4105DT3	PTS system, galactitol-specific IIc component
GN305_RS03730	ENOG4105F5H	Glycosyl Hydrolase Family 88
GN305_RS03750	ENOG4105E6M	Sulphatase-modifying factor protein
GN305_RS03765	ENOG4105DSG	hydrolase family 43
GN305_RS03805	ENOG4105CNT	hydrolase family 2
GN305_RS03825	ENOG4105M5J	Cupin 2, conserved barrel domain protein
GN305_RS03840	ENOG4107TDE	lipolytic protein G-D-S-L family
GN305_RS03855	ENOG4105C5Z	peptidase
GN305_RS03870	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GN305_RS03890	ENOG4105CJN	penicillin-binding protein
GN305_RS03895	ENOG4105CNI	cell division protein FtsW
GN305_RS03905	ENOG4105MA4	psp1 domain protein
GN305_RS03910	ENOG4105FA2	dna polymerase iii
GN305_RS03915	ENOG4105SYT	Methylenetetrahydrofolate reductase
GN305_RS03930	ENOG4108Z1Z	gCN5-related N-acetyltransferase
GN305_RS03945	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS03955	ENOG4105C02	permease
GN305_RS03960	ENOG4107T8J	thymidine kinase
GN305_RS04000	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS04010	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS04030	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GN305_RS04045	ENOG4107GFK	fumarate
GN305_RS04055	ENOG4105CUB	amino acid
GN305_RS04065	ENOG4105BZS	acriflavin resistance protein
GN305_RS04070	ENOG4105EFX	secretion protein, HlyD family
GN305_RS04080	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
GN305_RS04085	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GN305_RS04090	ENOG4105CVJ	phosphoglycerate mutase
GN305_RS04105	ENOG4107XII	Glycosyl Hydrolase Family 88
GN305_RS04110	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GN305_RS04115	ENOG4107R73	Mate efflux family protein
GN305_RS04125	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GN305_RS04140	ENOG41080R2	UPF0102 protein
GN305_RS04150	ENOG4108Z6B	deaminase
GN305_RS04160	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GN305_RS04165	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GN305_RS04170	ENOG4105C0B	DNA polymerase III (alpha subunit)
GN305_RS04195	ENOG4105K8N	protein family UPF0079, ATPase
GN305_RS04215	ENOG4105EIE	fructose-bisphosphate aldolase
GN305_RS04220	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GN305_RS04315	ENOG4105D49	3-dehydroquinate synthase
GN305_RS04330	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GN305_RS04335	ENOG4106H78	methyltransferase
GN305_RS04350	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
GN305_RS04355	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GN305_RS04360	ENOG4105DR5	peptidase
GN305_RS04370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GN305_RS04375	ENOG4107X35	defense response to bacterium
GN305_RS04385	ENOG4105FA0	parb-like partition protein
GN305_RS04390	ENOG4107QJE	Chromosome Partitioning Protein
GN305_RS04395	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
GN305_RS04400	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN305_RS04410	ENOG4105KNE	Phosphatidate cytidylyltransferase
GN305_RS04415	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GN305_RS04430	ENOG4105C99	atpase involved in dna repair
GN305_RS04435	ENOG4105CJW	magnesium transporter
GN305_RS04440	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GN305_RS04450	ENOG4105CIN	aminoacyl-histidine dipeptidase
GN305_RS04455	ENOG4107Y2X	deaminase
GN305_RS04475	ENOG4107S52	alpha-2-macroglobulin domain protein
GN305_RS04495	ENOG4105CTQ	phosphohexokinase
GN305_RS04500	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GN305_RS04505	ENOG4105CAT	Cytidine monophosphate kinase
GN305_RS04520	ENOG4105F8V	Hydrolase, tatD family
GN305_RS04560	ENOG4108VVK	transcriptional Regulator, AsnC
GN305_RS04565	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GN305_RS04575	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
GN305_RS04585	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS04595	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GN305_RS04600	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS04610	ENOG4105KIP	Thioesterase
GN305_RS04620	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GN305_RS04625	ENOG4108HMX	isocitrate dehydrogenase (NADP)
GN305_RS04645	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GN305_RS04675	ENOG4105CTQ	phosphohexokinase
GN305_RS04680	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GN305_RS04695	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GN305_RS04700	ENOG4105D9Q	decarboxylase (Beta subunit)
GN305_RS04705	ENOG4107ZT5	Thiol disulfide interchange protein
GN305_RS04715	ENOG4105TT1	Ragb susd domain-containing protein
GN305_RS04735	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS04750	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GN305_RS04760	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GN305_RS04770	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GN305_RS04775	ENOG4105C5Z	peptidase
GN305_RS04780	ENOG4105N5T	Radical SAM Protein
GN305_RS04785	ENOG4105CNW	domain protein
GN305_RS04790	ENOG4105D64	Mechanosensitive ion channel
GN305_RS04795	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
GN305_RS04800	ENOG4107QUV	Domain protein
GN305_RS04860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GN305_RS04865	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GN305_RS04870	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GN305_RS04875	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GN305_RS04880	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GN305_RS04890	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GN305_RS04900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS04920	ENOG4105I3K	Ferric uptake regulator, Fur family
GN305_RS04925	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GN305_RS04950	ENOG4107TDE	lipolytic protein G-D-S-L family
GN305_RS04965	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS04985	ENOG4105C5H	ABC transporter
GN305_RS04990	ENOG4105C9K	Endothelin-converting enzyme 1
GN305_RS05000	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GN305_RS05015	ENOG4105EPC	oxidoreductase
GN305_RS05020	ENOG4105CVG	Homoserine O-transsuccinylase
GN305_RS05025	ENOG4105CFP	Peptidase U32
GN305_RS05035	ENOG4107ZSV	Receptor
GN305_RS05050	ENOG4105DF9	Lipoate-protein, ligase
GN305_RS05060	ENOG4105CPP	Dehydrogenase, E1 component
GN305_RS05065	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GN305_RS05070	ENOG4105DZ0	fad dependent oxidoreductase
GN305_RS05080	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
GN305_RS05095	ENOG4105E3H	phosphoglycerate mutase
GN305_RS05100	ENOG4105D98	threonine synthase
GN305_RS05105	ENOG4105E0A	ABC, transporter
GN305_RS05110	ENOG4108I9K	permease protein
GN305_RS05120	ENOG4105CB5	ATP-dependent DNA helicase recG
GN305_RS05135	ENOG4105F6J	Alpha beta hydrolase fold
GN305_RS05155	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
GN305_RS05160	ENOG4105CHM	Aminotransferase
GN305_RS05170	ENOG4105KVH	Transcriptional regulator
GN305_RS05180	ENOG4105C87	Aminotransferase class I and II
GN305_RS05185	ENOG4105F4G	Membrane
GN305_RS05195	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
GN305_RS05200	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS05205	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GN305_RS05215	ENOG4107RAQ	aminopeptidase
GN305_RS05230	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
GN305_RS05245	ENOG4105WD1	Membrane
GN305_RS05255	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GN305_RS05295	ENOG4105CEM	UPF0597 protein
GN305_RS05370	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS05400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS05410	ENOG4105W5Q	DNA repair protein (RadC
GN305_RS05480	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS05505	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS05585	ENOG4105C4R	Atp-dependent dna helicase
GN305_RS05605	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS05645	ENOG4107QI1	Mate efflux family protein
GN305_RS05675	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
GN305_RS05685	ENOG4108R6W	Transcriptional regulator, ARAC family
GN305_RS05690	ENOG4105UYK	outer membrane protein a
GN305_RS05720	ENOG4105CNT	hydrolase family 2
GN305_RS05750	ENOG4105D05	Receptor
GN305_RS05755	ENOG4105CTK	cobaltochelatase, cobn subunit
GN305_RS05835	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS05845	ENOG4105BZA	Phosphoglycerate kinase
GN305_RS05855	ENOG4105E2D	ec 3.2.1.52
GN305_RS05875	ENOG4107QI1	Mate efflux family protein
GN305_RS05885	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GN305_RS05920	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS05925	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS05935	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GN305_RS05980	ENOG4105CRQ	synthase (Component I)
GN305_RS06000	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GN305_RS06015	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GN305_RS06020	ENOG4105CSM	endonuclease III
GN305_RS06025	ENOG4107TUM	Amidinotransferase
GN305_RS06035	ENOG4105C8Y	Acetylornithine aminotransferase
GN305_RS06045	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GN305_RS06080	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS06105	ENOG4105DFS	Conserved Protein
GN305_RS06120	ENOG4105C6E	dna polymerase iii
GN305_RS06135	ENOG4105CZH	peptidase
GN305_RS06140	ENOG4105CZH	peptidase
GN305_RS06165	ENOG4105CD3	dihydroorotase
GN305_RS06170	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
GN305_RS06220	ENOG4108JA2	transcriptioN-repair coupling factor
GN305_RS06230	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GN305_RS06250	ENOG4105DZS	Phenylacetate-CoA ligase
GN305_RS06260	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GN305_RS06265	ENOG4105CCT	upf0313 protein
GN305_RS06280	ENOG41084I7	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
GN305_RS06295	ENOG4105CTQ	phosphohexokinase
GN305_RS06310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GN305_RS06355	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GN305_RS06405	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GN305_RS06420	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
GN305_RS06435	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GN305_RS06440	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
GN305_RS06450	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GN305_RS06460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GN305_RS06465	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GN305_RS06470	ENOG4105C5H	ABC transporter
GN305_RS06490	ENOG4105K8R	UPF0145 protein
GN305_RS06530	ENOG4107X35	defense response to bacterium
GN305_RS06540	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS06545	ENOG4107RBB	ABC transporter, permease
GN305_RS06555	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS06565	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS06590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS06595	ENOG4105BZU	Histidine kinase
GN305_RS06615	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
GN305_RS06620	ENOG4105DBI	uridine monophosphokinase
GN305_RS06625	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS06755	ENOG4105FRN	stage II sporulation protein
GN305_RS06765	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS06820	ENOG4105BZU	Histidine kinase
GN305_RS06835	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GN305_RS06840	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GN305_RS06845	ENOG4105CTQ	phosphohexokinase
GN305_RS06860	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GN305_RS06865	ENOG4105EIE	fructose-bisphosphate aldolase
GN305_RS06875	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GN305_RS06935	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS07055	ENOG4108RE9	Phosphodiesterase
GN305_RS07105	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS07210	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GN305_RS07215	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GN305_RS07220	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GN305_RS07225	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GN305_RS07240	ENOG4105KY8	Rubrerythrin
GN305_RS07245	ENOG4105NGQ	Thioredoxin
GN305_RS07265	ENOG4105CIN	aminoacyl-histidine dipeptidase
GN305_RS07275	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GN305_RS07280	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
GN305_RS07310	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GN305_RS07315	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS07335	ENOG4105CFG	Acts as a chaperone (By similarity)
GN305_RS07375	ENOG4108UW5	maltose o-acetyltransferase
GN305_RS07395	ENOG4105K64	Glycosyl transferase, family 2
GN305_RS07410	ENOG4105D5D	udp-galactopyranose mutase
GN305_RS07420	ENOG4105D3Q	Sugar transferase
GN305_RS07460	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GN305_RS07480	ENOG4105DTQ	mandelate racemase muconate lactonizing
GN305_RS07490	ENOG4108IPT	Naphthoate synthase
GN305_RS07495	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
GN305_RS07500	ENOG4105E4F	Isochorismate synthase
GN305_RS07505	ENOG4105KA0	thioesterase Superfamily protein
GN305_RS07510	ENOG4107QWE	)-transporter
GN305_RS07520	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
GN305_RS07530	ENOG4105CMQ	Chloride channel
GN305_RS07535	ENOG4105WPN	DNA integration recombination invertion protein
GN305_RS07555	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS07570	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
GN305_RS07575	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GN305_RS07600	ENOG4105EJQ	L-serine dehydratase
GN305_RS07645	ENOG4108D32	Methyltransferase
GN305_RS07655	ENOG4105VTR	Integrase
GN305_RS07660	ENOG4105C98	muts2 protein
GN305_RS07685	ENOG4105EXC	Acyl-transferase
GN305_RS07695	ENOG4105C59	p-type ATPase
GN305_RS07705	ENOG4105EMU	Dehydrogenase
GN305_RS07715	ENOG4105D9Q	decarboxylase (Beta subunit)
GN305_RS07720	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
GN305_RS07730	ENOG4107QX3	carboxylase
GN305_RS07745	ENOG4108DBC	nitroreductase
GN305_RS07760	ENOG410667J	hydrolase
GN305_RS07765	ENOG4108Z03	MAF-like protein
GN305_RS07790	ENOG4105EQ0	Major Facilitator superfamily
GN305_RS07800	ENOG4105U5Y	Transcriptional regulator
GN305_RS07810	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GN305_RS07815	ENOG4105BZ1	(ABC) transporter
GN305_RS07970	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GN305_RS07980	ENOG4108S0S	Nucleotidyl transferase
GN305_RS07985	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
GN305_RS07990	ENOG4105C2W	permease
GN305_RS07995	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
GN305_RS08010	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
GN305_RS08020	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GN305_RS08025	ENOG4108V0P	LemA family
GN305_RS08040	ENOG4105E2X	shikimate dehydrogenase
GN305_RS08045	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GN305_RS08050	ENOG4107QWK	SAICAR synthetase
GN305_RS08055	ENOG4105C9A	Phoh family
GN305_RS08065	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GN305_RS08080	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
GN305_RS08090	ENOG4105C01	Dihydroxy-acid dehydratase
GN305_RS08110	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GN305_RS08135	ENOG4107RCQ	(CBS) domain
GN305_RS08155	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GN305_RS08170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GN305_RS08190	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS08200	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GN305_RS08205	ENOG4105DXN	mazG family
GN305_RS08230	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS08235	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
GN305_RS08245	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GN305_RS08255	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GN305_RS08270	ENOG4108VAC	response regulator
GN305_RS08275	ENOG4108HRK	Histidine kinase
GN305_RS08315	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GN305_RS08325	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GN305_RS08330	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GN305_RS08355	ENOG4105EDR	glucose galactose transporter
GN305_RS08360	ENOG4107Y7Q	pfkb domain protein
GN305_RS08370	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS08390	ENOG4105CGK	Exodeoxyribonuclease III
GN305_RS08405	ENOG4105C2I	pirin domain protein
GN305_RS08420	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GN305_RS08430	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GN305_RS08445	ENOG4105CN1	protease
GN305_RS08450	ENOG4108UK2	deaminase
GN305_RS08460	ENOG4105DGW	oligopeptidase A
GN305_RS08475	ENOG4105CJ2	(LipO)protein
GN305_RS08480	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
GN305_RS08495	ENOG4105CKK	Glycosyl transferase, family 2
GN305_RS08510	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS08520	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GN305_RS08530	ENOG4105F5H	Glycosyl Hydrolase Family 88
GN305_RS08565	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GN305_RS08570	ENOG4105C30	Nad-dependent epimerase dehydratase
GN305_RS08575	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GN305_RS08595	ENOG4105ECJ	Glycosyl Transferase
GN305_RS08600	ENOG4106WTF	Glycosyl transferase, family 2
GN305_RS08610	ENOG4108UW5	maltose o-acetyltransferase
GN305_RS08615	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GN305_RS08635	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
GN305_RS08640	ENOG4108TJN	glycosyl transferase group 1
GN305_RS08650	ENOG4105FEA	Spore maturation protein
GN305_RS08720	ENOG4105D3Q	Sugar transferase
GN305_RS08795	ENOG4105D0C	transport protein
GN305_RS08800	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS08820	ENOG4105CNT	hydrolase family 2
GN305_RS08855	ENOG4105D3Q	Sugar transferase
GN305_RS08860	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
GN305_RS08885	ENOG4105K64	Glycosyl transferase, family 2
GN305_RS08890	ENOG4105CG5	Glycosyl transferase (Group 1
GN305_RS08895	ENOG4107QRS	glycosyltransferase group 2 family protein
GN305_RS08900	ENOG4105K64	Glycosyl transferase, family 2
GN305_RS08905	ENOG4108KMV	Glycosyl transferase (Group 1
GN305_RS08930	ENOG4107SJB	teichoic acid biosynthesis
GN305_RS08935	ENOG4107QRS	glycosyltransferase group 2 family protein
GN305_RS08945	ENOG4107QRS	glycosyltransferase group 2 family protein
GN305_RS08960	ENOG4108TJN	glycosyl transferase group 1
GN305_RS09000	ENOG4105D75	Capsular exopolysaccharide family
GN305_RS09060	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GN305_RS09065	ENOG4105CDV	Ompa motb domain protein
GN305_RS09090	ENOG4105D7N	magnesium and cobalt transport protein CorA
GN305_RS09095	ENOG4108YXU	transcriptional regulator AsnC family
GN305_RS09105	ENOG4105DQR	SNARE associated Golgi
GN305_RS09115	ENOG4105CJ3	phosphate transporter
GN305_RS09125	ENOG4105D05	Receptor
GN305_RS09160	ENOG4105BZU	Histidine kinase
GN305_RS09185	ENOG4105CUY	Mechanosensitive ion channel
GN305_RS09190	ENOG4105CEY	Amp-dependent synthetase and ligase
GN305_RS09200	ENOG4108R6K	riboflavin synthase, subunit alpha
GN305_RS09205	ENOG4107S2Z	UPF0761 membrane protein
GN305_RS09225	ENOG4105BZU	Histidine kinase
GN305_RS09230	ENOG4105CGH	5'-nucleotidase
GN305_RS09240	ENOG4105D05	Receptor
GN305_RS09280	ENOG4108KBJ	Inner membrane protein YkgB
GN305_RS09285	ENOG4105C0H	protease
GN305_RS09290	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GN305_RS09310	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GN305_RS09315	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
GN305_RS09330	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GN305_RS09340	ENOG4105C5H	ABC transporter
GN305_RS09345	ENOG4108KPZ	tonB-dependent Receptor
GN305_RS09415	ENOG4105K5M	30s ribosomal protein S16
GN305_RS09450	ENOG4107YR5	Diacylglycerol kinase
GN305_RS09455	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
GN305_RS09490	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
GN305_RS09495	ENOG4105CRE	cytochrome C
GN305_RS09515	ENOG41079HR	Phosphate-Selective Porin O and P
GN305_RS09530	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GN305_RS09545	ENOG4105C8Y	Acetylornithine aminotransferase
GN305_RS09550	ENOG4105C8Y	Acetylornithine aminotransferase
GN305_RS09555	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GN305_RS09565	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
GN305_RS09585	ENOG4108YZA	Nitrogen regulatory protein pii
GN305_RS09595	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
GN305_RS09600	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GN305_RS09605	ENOG4105DKW	ABC transporter
GN305_RS09610	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GN305_RS09615	ENOG4107RJ1	sodium solute
GN305_RS09620	ENOG4105EA8	2-Nitropropane dioxygenase
GN305_RS09630	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
GN305_RS09635	ENOG4105HDK	L-asparaginase
GN305_RS09665	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GN305_RS09670	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GN305_RS09675	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GN305_RS09685	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GN305_RS09700	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GN305_RS09705	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS09710	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS09720	ENOG4105DY9	regulatoR
GN305_RS09735	ENOG4108ZXC	Two component transcriptional regulator, luxr family
GN305_RS09740	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
GN305_RS09745	ENOG4107QR9	Iron-sulfur cluster binding protein
GN305_RS09760	ENOG4105F1A	Pyruvate formate-lyase
GN305_RS09785	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GN305_RS09795	ENOG4105CE1	Ferrous iron transport protein b
GN305_RS09810	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GN305_RS09815	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GN305_RS09830	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GN305_RS09845	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GN305_RS09850	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GN305_RS09855	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
GN305_RS09860	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
GN305_RS09870	ENOG4105E09	nadh pyrophosphatase
GN305_RS09875	ENOG4105BZM	domain protein
GN305_RS09895	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS09980	ENOG4108Q52	Methyltransferase cognate corrinoid protein
GN305_RS09995	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GN305_RS10000	ENOG4105KME	endoribonuclease L-psp
GN305_RS10025	ENOG4105C5H	ABC transporter
GN305_RS10045	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
GN305_RS10065	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GN305_RS10070	ENOG4107QQG	Dehydrogenase
GN305_RS10095	ENOG4107QPH	glycogen) synthase
GN305_RS10150	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GN305_RS10160	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GN305_RS10175	ENOG4108UJU	UPF0301 protein
GN305_RS10195	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
GN305_RS10200	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
GN305_RS10210	ENOG41061MV	Arylsulfatase
GN305_RS10220	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GN305_RS10225	ENOG4105GR3	Histidine kinase
GN305_RS10250	ENOG4105C9X	ppx gppa phosphatase
GN305_RS10260	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GN305_RS10275	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GN305_RS10285	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
GN305_RS10290	ENOG4105RGC	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GN305_RS10295	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GN305_RS10300	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GN305_RS10315	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
GN305_RS10325	ENOG4107STF	Involved in phosphonate degradation (By similarity)
GN305_RS10350	ENOG4105EEM	helicase
GN305_RS10355	ENOG4105HMI	Membrane
GN305_RS10375	ENOG4107QW4	alcohol dehydrogenase
GN305_RS10380	ENOG4105CKU	formyltetrahydrofolate synthetase
GN305_RS10400	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GN305_RS10405	ENOG4105C5X	domain protein
GN305_RS10410	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
GN305_RS10420	ENOG4105C59	p-type ATPase
GN305_RS10435	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GN305_RS10440	ENOG4108IQE	Amp-dependent synthetase and ligase
GN305_RS10445	ENOG4105CEP	NADH dehydrogenase
GN305_RS10475	ENOG4105WXW	Antirepressor
GN305_RS10495	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS10535	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GN305_RS10540	ENOG4108IUM	Glycogen debranching enzyme
GN305_RS10545	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GN305_RS10550	ENOG4105D78	K07001 NTE family protein
GN305_RS10555	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
GN305_RS10560	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
GN305_RS10570	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GN305_RS10595	ENOG4105VRS	hydrolase family 18
GN305_RS10605	ENOG4108Z66	YbaK ebsC protein
GN305_RS10610	ENOG4105DUX	Transporter
GN305_RS10615	ENOG4105DWU	Membrane
GN305_RS10630	ENOG4105DFD	Na H antiporter
GN305_RS10635	ENOG4105CTX	dehydratase
GN305_RS10655	ENOG4108K0D	peptidase, M48
GN305_RS10665	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GN305_RS10675	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GN305_RS10690	ENOG4108RWN	rrna methyltransferase
GN305_RS10730	ENOG4105Q2H	domain protein
GN305_RS10745	ENOG4105D2H	Uronic isomerase
GN305_RS10750	ENOG4105DEI	Mannitol dehydrogenase
GN305_RS10760	ENOG4105DVK	Precorrin-2 c20-methyltransferase
GN305_RS10770	ENOG4105EHG	Permease protein
GN305_RS10775	ENOG4105E0A	ABC, transporter
GN305_RS10780	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
GN305_RS10785	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
GN305_RS10790	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
GN305_RS10795	ENOG4105E4R	Precorrin-3B C17-methyltransferase
GN305_RS10810	ENOG4105FTV	AraC Family Transcriptional Regulator
GN305_RS10815	ENOG4105EQD	regulatoR
GN305_RS10820	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GN305_RS10830	ENOG4105D05	Receptor
GN305_RS10840	ENOG4105D05	Receptor
GN305_RS10845	ENOG4105SYT	Methylenetetrahydrofolate reductase
GN305_RS10850	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GN305_RS10855	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GN305_RS10875	ENOG4107QX3	carboxylase
GN305_RS10885	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GN305_RS10905	ENOG4107PPM	cobalt chelatase
GN305_RS10910	ENOG4105D05	Receptor
GN305_RS10915	ENOG4105D05	Receptor
GN305_RS10925	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GN305_RS10930	ENOG4108WBT	adenosyltransferase
GN305_RS10935	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
GN305_RS10945	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
GN305_RS10970	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
GN305_RS10990	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
GN305_RS11005	ENOG4105C1J	atp-dependent rna helicase
GN305_RS11010	ENOG4105EAC	phosphoserine phosphatase
GN305_RS11030	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GN305_RS11035	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GN305_RS11040	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
GN305_RS11045	ENOG4105CBD	Diacylglycerol kinase
GN305_RS11050	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GN305_RS11065	ENOG4105C19	ABC transporter
GN305_RS11110	ENOG4105BZU	Histidine kinase
GN305_RS11140	ENOG4105C2C	drug resistance transporter, Bcr CflA
GN305_RS11160	ENOG4105BZS	acriflavin resistance protein
GN305_RS11170	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GN305_RS11190	ENOG4105C9M	aspartyl-trna synthetase
GN305_RS11195	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GN305_RS11225	ENOG4105DFD	Na H antiporter
GN305_RS11235	ENOG4105CTZ	aminopeptidase c
GN305_RS11245	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GN305_RS11250	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GN305_RS11265	ENOG4105FAW	cDP-glucose 4,6-dehydratase
GN305_RS11275	ENOG4105CJR	Integral membrane protein (MviN
GN305_RS11295	ENOG4105ECJ	Glycosyl Transferase
GN305_RS11305	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
GN305_RS11310	ENOG4108TJN	glycosyl transferase group 1
GN305_RS11320	ENOG4105E3R	(LipO)protein
GN305_RS11350	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GN305_RS11355	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GN305_RS11360	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GN305_RS11365	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
GN305_RS11375	ENOG4105C1J	atp-dependent rna helicase
GN305_RS11380	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GN305_RS11385	ENOG4108JQ1	Dehydrogenase
GN305_RS11400	ENOG4105E2D	ec 3.2.1.52
GN305_RS11415	ENOG410667J	hydrolase
GN305_RS11425	ENOG4105KT7	mgtC SapB transporter
GN305_RS11435	ENOG4105C08	Histidine kinase
GN305_RS11445	ENOG4108YZ4	nudix hydrolase
GN305_RS11460	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
GN305_RS11475	ENOG4105BZP	glycoside hydrolase 15-related
GN305_RS11495	ENOG4105BZU	Histidine kinase
GN305_RS11520	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
GN305_RS11555	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS11575	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
GN305_RS11580	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GN305_RS11585	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
GN305_RS11595	ENOG4108UVJ	appr-1-p processing domain protein
GN305_RS11600	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS11610	ENOG4108HQS	Glycine betaine
GN305_RS11620	ENOG410631K	Membrane
GN305_RS11625	ENOG4108UW5	maltose o-acetyltransferase
GN305_RS11640	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GN305_RS11650	ENOG4105KDC	50s ribosomal protein l28
GN305_RS11655	ENOG41083ND	50S ribosomal protein L33
GN305_RS11665	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GN305_RS11670	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
GN305_RS11675	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GN305_RS11680	ENOG4105K70	DNA-binding protein
GN305_RS11685	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
GN305_RS11745	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GN305_RS11750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GN305_RS11760	ENOG4105D78	K07001 NTE family protein
GN305_RS11780	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GN305_RS11785	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GN305_RS11790	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GN305_RS11795	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
GN305_RS11800	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
GN305_RS11815	ENOG4105FYV	Amp nucleosidase
GN305_RS11830	ENOG4105EGD	dinuclear metal center protein, YbgI family
GN305_RS11840	ENOG4105C4B	ABC transporter, permease
GN305_RS11845	ENOG4105CJ1	ABC, transporter
GN305_RS11850	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GN305_RS11860	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
GN305_RS11875	ENOG4105ECY	inositol monophosphatase
GN305_RS11890	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GN305_RS11910	ENOG4105D0S	secretion protein (HlyD
GN305_RS11915	ENOG4105CJ1	ABC, transporter
GN305_RS11920	ENOG4107QWP	ABC-2 type transporter
GN305_RS11925	ENOG4105CJ1	ABC, transporter
GN305_RS11930	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GN305_RS11940	ENOG4108JQC	penicillin-binding protein 1A
GN305_RS11945	ENOG4105CXT	aspartate transcarbamylase
GN305_RS11950	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
GN305_RS11965	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GN305_RS11970	ENOG4107QI1	Mate efflux family protein
GN305_RS11975	ENOG4108ZG0	Ompa motb domain protein
GN305_RS11980	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
GN305_RS12000	ENOG4105EN6	Membrane
GN305_RS12015	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GN305_RS12020	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GN305_RS12025	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GN305_RS12030	ENOG4108YBP	pseudouridine synthase
GN305_RS12035	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GN305_RS12040	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
GN305_RS12070	ENOG4105DGW	oligopeptidase A
GN305_RS12090	ENOG4105CPK	Glycosyl transferase (Group 1
GN305_RS12100	ENOG4107T8Q	Glycosyl transferase (Group 1
GN305_RS12120	ENOG4105ECJ	Glycosyl Transferase
GN305_RS12145	ENOG4108V06	Glutathione peroxidase
GN305_RS12150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS12170	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GN305_RS12175	ENOG4105CDU	Replicative dna helicase
GN305_RS12180	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GN305_RS12185	ENOG4105CDY	transcriptional regulatory protein
GN305_RS12205	ENOG4107RBB	ABC transporter, permease
GN305_RS12210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS12225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS12230	ENOG4105BZU	Histidine kinase
GN305_RS12235	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
GN305_RS12240	ENOG4105C5F	glutamine synthetase
GN305_RS12295	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
GN305_RS12300	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
GN305_RS12305	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
GN305_RS12320	ENOG4105D41	biosynthesis protein thiH
GN305_RS12325	ENOG4105D06	uba thif-type nad fad binding protein
GN305_RS12330	ENOG4106032	Glutathionylspermidine synthase
GN305_RS12345	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GN305_RS12350	ENOG4108HM4	ABC transporter
GN305_RS12355	ENOG4105D38	putrescine abc transporter
GN305_RS12380	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS12385	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
GN305_RS12410	ENOG4107RQX	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
GN305_RS12415	ENOG4107RVI	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
GN305_RS12465	ENOG4107KET	secretion protein, HlyD family
GN305_RS12500	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GN305_RS12505	ENOG4105CBD	Diacylglycerol kinase
GN305_RS12510	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GN305_RS12520	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GN305_RS12525	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GN305_RS12545	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GN305_RS12555	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GN305_RS12575	ENOG4105E2D	ec 3.2.1.52
GN305_RS12590	ENOG4105CBG	Sulfatase
GN305_RS12635	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS12660	ENOG4105C26	Dehydrogenase
GN305_RS12670	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
GN305_RS12700	ENOG4105EAA	nucleoside
GN305_RS12720	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GN305_RS12750	ENOG4107RN3	metallophosphoesterase
GN305_RS12755	ENOG4105DR4	Methyltransferase
GN305_RS12770	ENOG4105CNU	cell division protein FtsK
GN305_RS12780	ENOG4105C3M	thioredoxin reductase
GN305_RS12785	ENOG4107RAN	Peptidase, M16
GN305_RS12795	ENOG4105CJ1	ABC, transporter
GN305_RS12800	ENOG4107TT5	NLP P60 protein
GN305_RS12805	ENOG4107XGZ	Hydrolase
GN305_RS12810	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GN305_RS12815	ENOG4105K46	50S ribosomal protein l27
GN305_RS12825	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
GN305_RS12830	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GN305_RS12840	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
GN305_RS12860	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
GN305_RS12875	ENOG4105DI5	UPF0365 protein
GN305_RS12880	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
GN305_RS13130	ENOG4107X35	defense response to bacterium
GN305_RS13200	ENOG4105E4C	Lytic transglycosylase catalytic
GN305_RS13220	ENOG4105DY9	regulatoR
GN305_RS13250	ENOG4108UUM	single-stranded DNA-binding protein
GN305_RS13265	ENOG41067XB	TonB family
GN305_RS13285	ENOG4107QJE	Chromosome Partitioning Protein
GN305_RS13300	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS13580	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN305_RS13590	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS13645	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS13660	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS13730	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
GN305_RS13750	ENOG4105E2A	Dehydrogenase
GN305_RS13765	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GN305_RS13770	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
GN305_RS13780	ENOG4105VXR	cytoplasmic protein
GN305_RS13785	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GN305_RS13810	ENOG4105D3G	Pseudouridine synthase
GN305_RS13815	ENOG4107QJQ	Mate efflux family protein
GN305_RS13820	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
GN305_RS13835	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GN305_RS13915	ENOG4108NEV	two component transcriptional regulator, LytTR family
GN305_RS13920	ENOG4108HRK	Histidine kinase
GN305_RS13940	ENOG4105DZW	Dipeptidase
GN305_RS13945	ENOG4105DR5	peptidase
GN305_RS13950	ENOG4105DCF	alanine dehydrogenase
GN305_RS13955	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GN305_RS13960	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GN305_RS13980	ENOG4105HMI	Membrane
GN305_RS13985	ENOG4105DUM	transcriptional regulator, lysR family
GN305_RS13995	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GN305_RS14015	ENOG4105VIE	preprotein translocase, subunit YajC
GN305_RS14020	ENOG4107R6T	Involved in the transcription termination process (By similarity)
GN305_RS14030	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GN305_RS14035	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GN305_RS14040	ENOG4105VEJ	Heat shock protein
GN305_RS14050	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
GN305_RS14055	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
GN305_RS14060	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
GN305_RS14070	ENOG4105WMR	Protein CrcB homolog
GN305_RS14095	ENOG4105HNY	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
GN305_RS14165	ENOG4105CV8	reductase
GN305_RS14175	ENOG4105CV8	reductase
GN305_RS14180	ENOG4105CNT	hydrolase family 2
GN305_RS14240	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GN305_RS14245	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
GN305_RS14260	ENOG4105CS1	NAD(P)H quinone oxidoreductase
GN305_RS14285	ENOG4107SET	aldo keto reductase
GN305_RS14290	ENOG4105DHF	Membrane
GN305_RS14295	ENOG4105FDR	Membrane
GN305_RS14300	ENOG4105ENX	hydrolase
GN305_RS14310	ENOG4105CPC	Aldo Keto reductase
GN305_RS14315	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
GN305_RS14340	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GN305_RS14345	ENOG4105C87	Aminotransferase class I and II
GN305_RS14350	ENOG4107QI1	Mate efflux family protein
GN305_RS14375	ENOG4105CV8	reductase
GN305_RS14385	ENOG4107SET	aldo keto reductase
GN305_RS14405	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
GN305_RS14490	ENOG4105D9P	serine threonine protein kinase
GN305_RS14520	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS14560	ENOG4105DVF	Cytosine-specific methyltransferase
GN305_RS14595	ENOG4108UKS	UPF0398 protein
GN305_RS14635	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS14640	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS14690	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS14695	ENOG4105BZU	Histidine kinase
GN305_RS14700	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GN305_RS14715	ENOG4105DFY	n-acylglucosamine 2-epimerase
GN305_RS14720	ENOG4105CT4	transporter
GN305_RS14725	ENOG4105HY2	Glycosidase related protein
GN305_RS14730	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
GN305_RS14750	ENOG4105I82	acetyl xylan esterase
GN305_RS14805	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GN305_RS14810	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GN305_RS14815	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GN305_RS14820	ENOG4105CAK	Cell division ATP-binding protein ftsE
GN305_RS14825	ENOG4105CFH	Aspartokinase
GN305_RS14830	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GN305_RS14855	ENOG4105DWU	Membrane
GN305_RS14865	ENOG4105CHM	Aminotransferase
GN305_RS14880	ENOG4105DFA	alanine racemase domain protein
GN305_RS14885	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
GN305_RS14890	ENOG4105CEY	Amp-dependent synthetase and ligase
GN305_RS14910	ENOG4105DZW	Dipeptidase
GN305_RS14935	ENOG4108IJ0	Aspartate ammonia-lyase
GN305_RS14940	ENOG4107AYK	membrAne
GN305_RS14950	ENOG4105CMR	udp-glucose 4-epimerase
GN305_RS14960	ENOG4105DGN	Electron transport complex
GN305_RS14965	ENOG4105DZB	Electron transport complex
GN305_RS14970	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
GN305_RS14975	ENOG4105D6A	Electron transport complex
GN305_RS14980	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
GN305_RS14985	ENOG4108R3D	Electron transport complex
GN305_RS14995	ENOG4105C7B	Threonine dehydratase
GN305_RS15000	ENOG4106UX7	integral membrane protein
GN305_RS15010	ENOG4105CVK	Glutamate decarboxylase
GN305_RS15015	ENOG4105CSV	Glutaminase
GN305_RS15020	ENOG4106N3A	copper homeostasis protein cutc
GN305_RS15035	ENOG4105E5D	amino acid
GN305_RS15040	ENOG4105BZU	Histidine kinase
GN305_RS15045	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GN305_RS15050	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GN305_RS15070	ENOG4105C5I	Dehydrogenase
GN305_RS15075	ENOG4105D1H	recombination factor protein RarA
GN305_RS15140	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
GN305_RS15145	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
GN305_RS15170	ENOG4105CTC	Lipopolysaccharide biosynthesis protein-like protein
GN305_RS15185	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
GN305_RS15190	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GN305_RS15235	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS15240	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS15355	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS15380	ENOG4105EKQ	RNA-directed DNA polymerase
GN305_RS15535	ENOG4106611	bacteriocin immunity
GN305_RS15540	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS15560	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS15575	ENOG4105DFS	Conserved Protein
GN305_RS15605	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GN305_RS15625	ENOG4105C8U	phosphate abc transporter
GN305_RS15630	ENOG4105PWN	phosphate abc transporter
GN305_RS15635	ENOG4105CX6	glutaminyL-tRNA synthetase
GN305_RS15650	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
GN305_RS15655	ENOG4105C30	Nad-dependent epimerase dehydratase
GN305_RS15660	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
GN305_RS15665	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GN305_RS15670	ENOG4105D3Q	Sugar transferase
GN305_RS15675	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GN305_RS15680	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
GN305_RS15690	ENOG4107V1M	polysaccharide export protein
GN305_RS15695	ENOG4105C93	Xylose Isomerase
GN305_RS15700	ENOG4105CMG	Carbohydrate kinase
GN305_RS15760	ENOG4107QRS	glycosyltransferase group 2 family protein
GN305_RS15765	ENOG4105ECJ	Glycosyl Transferase
GN305_RS15775	ENOG4105EY8	ABC transporter
GN305_RS15785	ENOG4105CG5	Glycosyl transferase (Group 1
GN305_RS15805	ENOG4105CG5	Glycosyl transferase (Group 1
GN305_RS15815	ENOG4108I69	Glycosyl transferases group 1
GN305_RS15830	ENOG4105CPK	Glycosyl transferase (Group 1
GN305_RS15835	ENOG4105CKK	Glycosyl transferase, family 2
GN305_RS15840	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GN305_RS15845	ENOG4105BZU	Histidine kinase
GN305_RS15860	ENOG4108IAJ	Nad-dependent epimerase dehydratase
GN305_RS15865	ENOG4105DWF	phosphomethylpyrimidine kinase
GN305_RS15870	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GN305_RS15880	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
GN305_RS15895	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GN305_RS15900	ENOG4105VN1	Heat shock protein
GN305_RS15905	ENOG4105BZU	Histidine kinase
GN305_RS15915	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GN305_RS15920	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GN305_RS15925	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
GN305_RS15940	ENOG4105CAQ	asparagine synthetase
GN305_RS15985	ENOG410600T	transposase
GN305_RS16005	ENOG4105ESV	Glycosyl transferase, family 4
GN305_RS16020	ENOG4107RJ7	Glycosyl transferase (Group 1
GN305_RS16040	ENOG4105CPK	Glycosyl transferase (Group 1
GN305_RS16065	ENOG4108SMP	Nad-dependent epimerase dehydratase
GN305_RS16075	ENOG4105FAW	cDP-glucose 4,6-dehydratase
GN305_RS16080	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
GN305_RS16135	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
GN305_RS16140	ENOG4105HHA	aminodeoxychorismate lyase
GN305_RS16150	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GN305_RS16155	ENOG4105VJV	50s ribosomal protein L35
GN305_RS16160	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GN305_RS16165	ENOG4105C22	threonyL-tRNA synthetase
GN305_RS16175	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GN305_RS16180	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GN305_RS16225	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
GN305_RS16230	ENOG4107QNK	)-transporter
GN305_RS16255	ENOG410624X	efflux transporter, rnd family, mfp subunit
GN305_RS16285	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GN305_RS16290	ENOG4105CRQ	synthase (Component I)
GN305_RS16295	ENOG4105DDQ	anthranilate synthase
GN305_RS16300	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GN305_RS16305	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GN305_RS16310	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
GN305_RS16315	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GN305_RS16320	ENOG4105HDK	L-asparaginase
GN305_RS16325	ENOG4108WZ2	response regulator
GN305_RS16330	ENOG4105BZU	Histidine kinase
GN305_RS16340	ENOG4108JU5	Magnesium and cobalt efflux protein
GN305_RS16345	ENOG4108UUM	single-stranded DNA-binding protein
GN305_RS16355	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GN305_RS16360	ENOG4105C03	ribonuclease
GN305_RS16370	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN305_RS16380	ENOG4105CRK	lysyL-tRNA synthetase
GN305_RS16385	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GN305_RS16390	ENOG4107QP8	phosphohexose isomerase
GN305_RS16395	ENOG4107VXZ	Hydrolase
GN305_RS16425	ENOG4105E2R	ROK family
GN305_RS16440	ENOG4105DJB	Major Facilitator Superfamily
GN305_RS16445	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GN305_RS16450	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GN305_RS16460	ENOG4105ID8	Transcriptional regulator, ARAC family
GN305_RS16465	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
GN305_RS16525	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
GN305_RS16530	ENOG4105CE4	GlcNAc 6-P deacetylase
GN305_RS16535	ENOG4105CNT	hydrolase family 2
GN305_RS16545	ENOG4105E2D	ec 3.2.1.52
GN305_RS16555	ENOG4105E2D	ec 3.2.1.52
GN305_RS16575	ENOG4105E2D	ec 3.2.1.52
GN305_RS16590	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS16600	ENOG4105CU9	asparagine synthetase A
GN305_RS16605	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GN305_RS16620	ENOG4105EHZ	conserved protein UCP016719
GN305_RS16635	ENOG4105BZ1	(ABC) transporter
GN305_RS16655	ENOG4107QTH	restriction modification system DNA specificity domain
GN305_RS16660	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS16665	ENOG4107QTH	restriction modification system DNA specificity domain
GN305_RS16695	ENOG4105CVR	type I restriction-modification system
GN305_RS16700	ENOG4108F3G	Type I restriction-modification system, R subunit
GN305_RS16755	ENOG4105ENX	hydrolase
GN305_RS16770	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GN305_RS16780	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GN305_RS16785	ENOG4108DBC	nitroreductase
GN305_RS16800	ENOG4105KRF	dihydroneopterin aldolase
GN305_RS16810	ENOG4107YYJ	Glycosyl transferase, family 2
GN305_RS16815	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GN305_RS16820	ENOG4105CEY	Amp-dependent synthetase and ligase
GN305_RS16830	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GN305_RS16835	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GN305_RS16840	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
GN305_RS16865	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GN305_RS16870	ENOG4105CSA	Coproporphyrinogen iii oxidase
GN305_RS16920	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
GN305_RS16930	ENOG4105DSG	hydrolase family 43
GN305_RS16945	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS16950	ENOG4105DSG	hydrolase family 43
GN305_RS16955	ENOG4105DT9	hydrolase family 43
GN305_RS16960	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
GN305_RS16965	ENOG4105CT4	transporter
GN305_RS16975	ENOG4107QKV	phosphomannomutase
GN305_RS16985	ENOG4105SFS	phosphoesterase RecJ domain protein
GN305_RS16990	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
GN305_RS16995	ENOG4105DJV	ribulose-phosphate 3-epimerase
GN305_RS17015	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GN305_RS17025	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GN305_RS17030	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS17085	ENOG4105CE4	GlcNAc 6-P deacetylase
GN305_RS17120	ENOG4105C3F	Signal peptidase i
GN305_RS17180	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GN305_RS17185	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GN305_RS17205	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GN305_RS17215	ENOG4105CAH	Chromate
GN305_RS17235	ENOG4105F32	YngK protein
GN305_RS17250	ENOG4105E2D	ec 3.2.1.52
GN305_RS17275	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GN305_RS17280	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GN305_RS17285	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
GN305_RS17290	ENOG4105DCI	Phosphohydrolase
GN305_RS17295	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN305_RS17300	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN305_RS17305	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN305_RS17315	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GN305_RS17330	ENOG4105K63	Thioredoxin
GN305_RS17335	ENOG4108V06	Glutathione peroxidase
GN305_RS17345	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS17360	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS17475	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
GN305_RS17510	ENOG4105CGS	Alpha-glucosidase
GN305_RS17550	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GN305_RS17565	ENOG4105D17	glycoside hydrolase, family 3 domain protein
GN305_RS17570	ENOG4105CGH	5'-nucleotidase
GN305_RS17575	ENOG4105CGH	5'-nucleotidase
GN305_RS17580	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GN305_RS17595	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
GN305_RS17600	ENOG4105F5H	Glycosyl Hydrolase Family 88
GN305_RS17605	ENOG4105CX8	fg-gap repeat protein
GN305_RS17660	ENOG4105EKC	
GN305_RS17665	ENOG4107TDE	lipolytic protein G-D-S-L family
GN305_RS17670	ENOG4105CX8	fg-gap repeat protein
GN305_RS17685	ENOG41061MV	Arylsulfatase
GN305_RS17705	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS17725	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS17765	ENOG4105CX8	fg-gap repeat protein
GN305_RS17780	ENOG4105C4C	beta-galactosidase
GN305_RS17795	ENOG4107TDE	lipolytic protein G-D-S-L family
GN305_RS17815	ENOG4105DDI	hemolysin-type calcium-binding region
GN305_RS17830	ENOG4105D44	asparaginase
GN305_RS17835	ENOG4105QJH	Domain of unknown function (DUF718)
GN305_RS17840	ENOG4105DKQ	ROK family
GN305_RS17850	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS17855	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
GN305_RS17875	ENOG4105QNR	S1 RNA binding domain protein
GN305_RS17880	ENOG4108I6A	alcohol dehydrogenase
GN305_RS17890	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GN305_RS17895	ENOG4105CUZ	uba thif-type nad fad binding protein
GN305_RS17905	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GN305_RS17915	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
GN305_RS17920	ENOG4105DF5	DNA topoisomerase IV, subunit A
GN305_RS17970	ENOG4105TT1	Ragb susd domain-containing protein
GN305_RS17995	ENOG4105EDR	glucose galactose transporter
GN305_RS18000	ENOG4105CPQ	Dehydrogenase
GN305_RS18005	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
GN305_RS18040	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
GN305_RS18065	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
GN305_RS18095	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GN305_RS18100	ENOG4105C6K	Malic enzyme
GN305_RS18105	ENOG4107R37	Glutamate dehydrogenase
GN305_RS18145	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
GN305_RS18150	ENOG4105GTN	ParB Domain Protein Nuclease
GN305_RS18160	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GN305_RS18175	ENOG4107V40	secretion protein, HlyD family
GN305_RS18220	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GN305_RS18225	ENOG41084DP	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GN305_RS18230	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GN305_RS18240	ENOG4107R73	Mate efflux family protein
GN305_RS18300	ENOG4105C4X	radical SAM domain protein
GN305_RS18380	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GN305_RS18390	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GN305_RS18405	ENOG4105CNT	hydrolase family 2
GN305_RS18410	ENOG4107WCA	isomerase
GN305_RS18435	ENOG4105C5H	ABC transporter
GN305_RS18440	ENOG4105D0C	transport protein
GN305_RS18445	ENOG4105CMN	Methylmalonyl-coA mutase
GN305_RS18450	ENOG4105D5P	Methylmalonyl-coA mutase
GN305_RS18470	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS18475	ENOG4105BZU	Histidine kinase
GN305_RS18480	ENOG4105CUY	Mechanosensitive ion channel
GN305_RS18515	ENOG4105BZJ	Electron transfer flavoprotein
GN305_RS18520	ENOG4105C10	Electron transfer flavoprotein
GN305_RS18540	ENOG41082VF	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GN305_RS18550	ENOG4105CVR	type I restriction-modification system
GN305_RS18595	ENOG4105CGP	Urocanate hydratase
GN305_RS18600	ENOG4105CCS	Glutamate formiminotransferase
GN305_RS18605	ENOG4105CI2	imidazolone-5-propionate hydrolase
GN305_RS18610	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
GN305_RS18615	ENOG4105C84	Histidine ammonia-lyase
GN305_RS18620	ENOG4108XXK	NUDIX hydrolase
GN305_RS18630	ENOG4108V4B	ThiJ pfpI
GN305_RS18650	ENOG4105EPC	oxidoreductase
GN305_RS18655	ENOG4108V2W	Carbonate dehydratase
GN305_RS18675	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GN305_RS18680	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GN305_RS18690	ENOG4107QW8	radical SAM domain protein
GN305_RS18700	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GN305_RS18705	ENOG4105CUT	histidyl-tRNA synthetase
GN305_RS18710	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
GN305_RS18725	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
GN305_RS18730	ENOG4108IUS	Transketolase
GN305_RS18735	ENOG4108HHA	Transketolase
GN305_RS18740	ENOG4105E98	transcriptional regulator DeoR family
GN305_RS18745	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GN305_RS18825	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GN305_RS18835	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
GN305_RS18845	ENOG4107QI1	Mate efflux family protein
GN305_RS18850	ENOG4105BZU	Histidine kinase
GN305_RS18855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GN305_RS18865	ENOG4105C34	Pseudouridine synthase
GN305_RS18870	ENOG4105CHR	reductase
GN305_RS18885	ENOG4105CNT	hydrolase family 2
GN305_RS18905	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS18910	ENOG4105C1J	atp-dependent rna helicase
GN305_RS18930	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GN305_RS18935	ENOG4105WH1	Two component transcriptional regulator luxr family
GN305_RS18965	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GN305_RS18980	ENOG4105D1Q	UPF0246 protein
GN305_RS18985	ENOG4105RWF	major outer membrane protein OmpA
GN305_RS18995	ENOG4107QK2	May be the GTPase, regulating ATP sulfurylase activity (By similarity)
GN305_RS19000	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GN305_RS19005	ENOG4107TBF	Catalyzes the synthesis of activated sulfate (By similarity)
GN305_RS19015	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GN305_RS19025	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GN305_RS19040	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
GN305_RS19055	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GN305_RS19060	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS19065	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GN305_RS19070	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GN305_RS19075	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GN305_RS19080	ENOG4105VFU	Rna-binding protein
GN305_RS19085	ENOG4108IUZ	ABC transporter
GN305_RS19095	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
GN305_RS19100	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GN305_RS19105	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GN305_RS19110	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GN305_RS19165	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
GN305_RS19170	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GN305_RS19175	ENOG4105EUJ	GTP cyclohydrolase i
GN305_RS19195	ENOG4105DR5	peptidase
GN305_RS19200	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GN305_RS19210	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GN305_RS19225	ENOG4109015	Biopolymer transport protein exbD tolR
GN305_RS19235	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GN305_RS19240	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GN305_RS19265	ENOG4105EYH	Exonuclease
GN305_RS19270	ENOG4107RH8	nuclease SbcCD subunit D
GN305_RS19285	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19290	ENOG4105ECQ	AraC Family Transcriptional Regulator
GN305_RS19335	ENOG4107QUV	Domain protein
GN305_RS19360	ENOG4105DSG	hydrolase family 43
GN305_RS19380	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19405	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
GN305_RS19410	ENOG4105EEI	dihydropteroate synthase
GN305_RS19415	ENOG4105C8B	TIGR00159 family
GN305_RS19430	ENOG41067MG	lrgb family
GN305_RS19435	ENOG4105VAW	lrga family
GN305_RS19440	ENOG4108IJ2	phosphate acetyltransferase
GN305_RS19445	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
GN305_RS19450	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GN305_RS19455	ENOG4105VG1	fes assembly suf system protein
GN305_RS19460	ENOG4105W5Q	DNA repair protein (RadC
GN305_RS19465	ENOG4105K64	Glycosyl transferase, family 2
GN305_RS19470	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GN305_RS19475	ENOG4105VG0	50S ribosomal protein l34
GN305_RS19480	ENOG4105C4X	radical SAM domain protein
GN305_RS19490	ENOG4105SBG	acid phosphatase
GN305_RS19510	ENOG4105E2D	ec 3.2.1.52
GN305_RS19515	ENOG4105CBG	Sulfatase
GN305_RS19555	ENOG4105C34	Pseudouridine synthase
GN305_RS19560	ENOG4105CPF	Cell wall formation (By similarity)
GN305_RS19585	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
GN305_RS19590	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
GN305_RS19595	ENOG4108X4Q	Hydrolase
GN305_RS19620	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19640	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19675	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19705	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
GN305_RS19710	ENOG4107VRI	Transcriptional regulator
GN305_RS19725	ENOG4105HEE	Binding Domain protein
GN305_RS19735	ENOG4105E0M	Sulfatase
GN305_RS19740	ENOG4105II7	pyrroline-5-carboxylate reductase
GN305_RS19745	ENOG4105C8Y	Acetylornithine aminotransferase
GN305_RS19750	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GN305_RS19755	ENOG4105CDH	Citrulline--aspartate ligase
GN305_RS19765	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
GN305_RS19770	ENOG4105DET	Rhamnulokinase
GN305_RS19775	ENOG4105DKG	l-rhamnose isomerase
GN305_RS19785	ENOG4105C9J	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde (By similarity)
GN305_RS19805	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS19815	ENOG4105ECQ	AraC Family Transcriptional Regulator
GN305_RS19820	ENOG4105E9H	Lytic Murein transglycosylase
GN305_RS19825	ENOG4105EYW	Ion transport protein
GN305_RS19830	ENOG4105CNT	hydrolase family 2
GN305_RS19850	ENOG4105EPC	oxidoreductase
GN305_RS19875	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
GN305_RS19880	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
GN305_RS19885	ENOG4105CKB	glycosidase
GN305_RS19940	ENOG4105CWX	Alpha-1,2-mannosidase
GN305_RS19975	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GN305_RS19990	ENOG4107QI1	Mate efflux family protein
GN305_RS20000	ENOG4108KX4	response regulator
GN305_RS20005	ENOG4105EX0	alpha-galactosidase
GN305_RS20010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS20060	ENOG4105TT1	Ragb susd domain-containing protein
GN305_RS20080	ENOG4105E4I	Glycoside hydrolase family 28
GN305_RS20090	ENOG41063TF	transcriptional regulator (AraC
GN305_RS20105	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GN305_RS20135	ENOG4107HQ7	repeat protein
GN305_RS20150	ENOG4105CWX	Alpha-1,2-mannosidase
GN305_RS20185	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS20215	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS20250	ENOG4108ZT0	50S ribosomal protein l17
GN305_RS20255	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN305_RS20260	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GN305_RS20265	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GN305_RS20270	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GN305_RS20275	ENOG410864M	50S ribosomal protein L36
GN305_RS20280	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GN305_RS20290	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GN305_RS20295	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GN305_RS20300	ENOG41084HK	50S ribosomal protein L30
GN305_RS20305	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GN305_RS20310	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GN305_RS20315	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GN305_RS20320	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GN305_RS20325	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GN305_RS20330	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GN305_RS20335	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GN305_RS20340	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GN305_RS20345	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GN305_RS20350	ENOG41062E3	50S ribosomal protein L29
GN305_RS20355	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GN305_RS20360	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GN305_RS20365	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GN305_RS20370	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GN305_RS20375	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GN305_RS20380	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GN305_RS20385	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GN305_RS20390	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GN305_RS20395	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GN305_RS20400	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GN305_RS20405	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GN305_RS20410	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GN305_RS20420	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN305_RS20425	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN305_RS20430	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GN305_RS20435	ENOG4107VNI	ribosomal protein l10
GN305_RS20440	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GN305_RS20445	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GN305_RS20465	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GN305_RS20495	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS20500	ENOG41083X6	30S ribosomal protein S21
GN305_RS20510	ENOG4108Z0R	Transferase
GN305_RS20525	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
GN305_RS20530	ENOG4105BZU	Histidine kinase
GN305_RS20540	ENOG4105CN1	protease
GN305_RS20585	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
GN305_RS20590	ENOG4105CWX	Alpha-1,2-mannosidase
GN305_RS20595	ENOG4105DDI	hemolysin-type calcium-binding region
GN305_RS20615	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS20640	ENOG4108JU3	Alkyl hydroperoxide reductase
GN305_RS20645	ENOG4105D3R	alkyl hydroperoxide reductase
GN305_RS20650	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GN305_RS20670	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
GN305_RS20675	ENOG4105CNT	hydrolase family 2
GN305_RS20690	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS20750	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS20785	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GN305_RS20820	ENOG4108SM1	rRNA (Adenine-N(6)-)-methyltransferase
GN305_RS20835	ENOG4108IQE	Amp-dependent synthetase and ligase
GN305_RS20880	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GN305_RS20885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GN305_RS20900	ENOG4105DCG	PHP domain protein
GN305_RS20905	ENOG4105C25	Primosomal protein n'
GN305_RS20940	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS20945	ENOG4105F5P	DNA-damage-inducible protein d
GN305_RS20950	ENOG4107XZC	Restriction modification system DNA (Specificity
GN305_RS20960	ENOG4105CVR	type I restriction-modification system
GN305_RS21005	ENOG4108WBT	adenosyltransferase
GN305_RS21020	ENOG4107QX3	carboxylase
GN305_RS21030	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GN305_RS21035	ENOG4105K78	MarR family Transcriptional regulator
GN305_RS21125	ENOG4106QJ6	Integrase catalytic subunit
GN305_RS21155	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GN305_RS21165	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GN305_RS21175	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GN305_RS21180	ENOG4105VCQ	rubredoxin
GN305_RS21185	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
GN305_RS21190	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GN305_RS21195	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GN305_RS21215	ENOG4105DBI	uridine monophosphokinase
GN305_RS21225	ENOG4105C6N	Formate acetyltransferase
GN305_RS21230	ENOG4105F1A	Pyruvate formate-lyase
GN305_RS21235	ENOG4107RAQ	aminopeptidase
GN305_RS21240	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GN305_RS21250	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GN305_RS21255	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
GN305_RS21260	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GN305_RS21265	ENOG4105CSV	Glutaminase
GN305_RS21270	ENOG4105VFU	Rna-binding protein
GN305_RS21290	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
GN305_RS21295	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GN305_RS21315	ENOG4107YM1	mraZ protein
GN305_RS21320	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GN305_RS21330	ENOG4105CJN	penicillin-binding protein
GN305_RS21335	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GN305_RS21340	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GN305_RS21345	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GN305_RS21350	ENOG4105CNI	cell division protein FtsW
GN305_RS21355	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GN305_RS21360	ENOG4105DFU	Cell wall formation (By similarity)
GN305_RS21370	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GN305_RS21375	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GN305_RS21385	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
GN305_RS21395	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
GN305_RS21400	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GN305_RS21405	ENOG4107S1W	4-alpha-glucanotransferase
GN305_RS21430	ENOG4108IUK	alpha amylase, catalytic
GN305_RS21455	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS21465	ENOG4106JX8	Outer membrane protein SusF
GN305_RS21475	ENOG41088V8	Aamy
GN305_RS21505	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GN305_RS21515	ENOG4105EHF	Converts the aldose L-fucose into the corresponding ketose L-fuculose (By similarity)
GN305_RS21520	ENOG4105EDR	glucose galactose transporter
GN305_RS21525	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GN305_RS21535	ENOG4105C27	TonB-dependent Receptor Plug
GN305_RS21550	ENOG4105DWU	Membrane
GN305_RS21555	ENOG4105CNT	hydrolase family 2
GN305_RS21560	ENOG4107WCA	isomerase
GN305_RS21590	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GN305_RS21595	ENOG4105CHV	Transcription elongation factor NusA
GN305_RS21600	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
GN305_RS21610	ENOG4105F27	Major Facilitator
GN305_RS21635	ENOG4105I82	acetyl xylan esterase
GN305_RS21655	ENOG4105EMN	RNA polymerase sigma factor
GN305_RS21660	ENOG4107T6X	nag kinase
GN305_RS21665	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
GN305_RS21670	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GN305_RS21690	ENOG4105E09	nadh pyrophosphatase
GN305_RS21705	ENOG4108VVK	transcriptional Regulator, AsnC
GN305_RS21730	ENOG4105CKM	Branched-chain carboxylic acid kinase
GN305_RS21735	ENOG4107RE7	phosphate butyryltransferase
GN305_RS21740	ENOG4108Z86	Glutamine amidotransferase
GN305_RS21785	ENOG4105NGQ	Thioredoxin
GN305_RS21840	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
GN305_RS21850	ENOG4105DTN	riboflavin biosynthesis protein ribF
GN305_RS21885	ENOG4105VMP	Transcriptional regulator
GN305_RS21910	ENOG4105CZH	peptidase
GN305_RS21925	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
GN305_RS21930	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
GN305_RS22020	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GN305_RS22025	ENOG4105CD8	aminopeptidase N
GN305_RS22040	ENOG4105C2X	Arabinose 5-phosphate isomerase
GN305_RS22045	ENOG4108URH	decarboxylase
GN305_RS22060	ENOG4105BZU	Histidine kinase
GN305_RS22065	ENOG4105CBG	Sulfatase
GN305_RS22080	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
GN305_RS22085	ENOG4105DMW	Dehydrogenase reductase
GN305_RS22095	ENOG4105C3F	Signal peptidase i
GN305_RS22100	ENOG4105C3F	Signal peptidase i
GN305_RS22105	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GN305_RS22120	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
GN305_RS22130	ENOG4105C0A	alcohol dehydrogenase
GN305_RS22220	ENOG4105CN1	protease
GN305_RS22225	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GN305_RS22230	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
GN305_RS22255	ENOG4105DY9	regulatoR
GN305_RS22305	ENOG4105GR3	Histidine kinase
GN305_RS22310	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GN305_RS22330	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GN305_RS22345	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)