locus-tag	class	description
GN306_RS00005	COG0445	tRNA wobble uridine modification
GN306_RS00010	COG2268	Band 7 protein
GN306_RS00020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GN306_RS00040	COG0745	RESPONSE REGULATOR receiver
GN306_RS00045	COG5002	protein histidine kinase activity
GN306_RS00050	COG0700	Nucleoside recognition
GN306_RS00095	COG3279	Response regulator of the LytR AlgR family
GN306_RS00125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GN306_RS00130	COG0793	Belongs to the peptidase S41A family
GN306_RS00130	COG3409	Peptidoglycan-binding domain 1 protein
GN306_RS00145	COG1053	succinate dehydrogenase
GN306_RS00200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GN306_RS00200	COG0758	DNA mediated transformation
GN306_RS00220	COG1454	alcohol dehydrogenase
GN306_RS00230	COG0584	glycerophosphoryl diester phosphodiesterase
GN306_RS00245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GN306_RS00250	COG0681	Belongs to the peptidase S26 family
GN306_RS00255	COG0681	Belongs to the peptidase S26 family
GN306_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS00270	COG1312	Catalyzes the dehydration of D-mannonate
GN306_RS00275	COG4771	TonB-dependent receptor
GN306_RS00285	COG3119	arylsulfatase activity
GN306_RS00290	COG2198	Histidine kinase
GN306_RS00290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS00290	COG0784	Response regulator, receiver
GN306_RS00290	COG2205	protein histidine kinase activity
GN306_RS00300	COG0612	Peptidase, M16
GN306_RS00310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GN306_RS00310	COG0517	IMP dehydrogenase activity
GN306_RS00325	COG0308	aminopeptidase N
GN306_RS00330	COG0482	sulfurtransferase activity
GN306_RS00420	COG4974	Belongs to the 'phage' integrase family
GN306_RS00425	COG2255	four-way junction helicase activity
GN306_RS00440	COG3591	Belongs to the peptidase S1B family
GN306_RS00465	COG3655	Transcriptional regulator
GN306_RS00500	COG0196	riboflavin kinase activity
GN306_RS00505	COG1011	Hydrolase
GN306_RS00510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GN306_RS00575	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GN306_RS00600	COG2166	iron-sulfur cluster assembly
GN306_RS00610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GN306_RS00615	COG0280	phosphate acetyltransferase
GN306_RS00620	COG3426	butyrate kinase activity
GN306_RS00645	COG1522	sequence-specific DNA binding
GN306_RS00655	COG1253	flavin adenine dinucleotide binding
GN306_RS00680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GN306_RS00685	COG1166	arginine decarboxylase activity
GN306_RS00690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GN306_RS00695	COG1595	DNA-templated transcription, initiation
GN306_RS00715	COG3458	cephalosporin-C deacetylase activity
GN306_RS00740	COG2814	Major facilitator Superfamily
GN306_RS00750	COG0779	Required for maturation of 30S ribosomal subunits
GN306_RS00755	COG0195	Participates in both transcription termination and antitermination
GN306_RS00760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GN306_RS00770	COG0719	Fe-S assembly protein
GN306_RS00775	COG0396	ATPase activity
GN306_RS00780	COG0719	Fe-S assembly protein
GN306_RS00785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GN306_RS00790	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GN306_RS00790	COG3408	Glycogen debranching enzyme
GN306_RS00795	COG3250	beta-galactosidase activity
GN306_RS00800	COG2431	L-lysine efflux transmembrane transporter activity
GN306_RS00810	COG0702	epimerase
GN306_RS00815	COG4206	TonB-dependent receptor
GN306_RS00815	COG1629	transport
GN306_RS00825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GN306_RS00830	COG0738	Major facilitator superfamily
GN306_RS00835	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
GN306_RS00845	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GN306_RS00875	COG0366	Alpha amylase catalytic
GN306_RS00890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN306_RS00895	COG1629	transport
GN306_RS00895	COG4206	TonB-dependent receptor
GN306_RS00905	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN306_RS00915	COG1082	Xylose isomerase domain protein TIM barrel
GN306_RS00920	COG0366	Alpha amylase catalytic
GN306_RS00945	COG1640	4-alpha-glucanotransferase
GN306_RS00950	COG0187	DNA topoisomerase II activity
GN306_RS00955	COG0268	Binds directly to 16S ribosomal RNA
GN306_RS00965	COG1381	Involved in DNA repair and RecF pathway recombination
GN306_RS00975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GN306_RS00990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GN306_RS00995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GN306_RS01000	COG0772	Belongs to the SEDS family
GN306_RS01005	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GN306_RS01010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GN306_RS01015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GN306_RS01020	COG0768	penicillin binding
GN306_RS01030	COG0275	rRNA processing
GN306_RS01035	COG2001	Belongs to the MraZ family
GN306_RS01055	COG0756	dUTP diphosphatase activity
GN306_RS01060	COG3063	Type IV pilus biogenesis stability protein PilW
GN306_RS01080	COG0724	RNA recognition motif
GN306_RS01085	COG2066	Belongs to the glutaminase family
GN306_RS01090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GN306_RS01095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GN306_RS01100	COG0509	glycine decarboxylation via glycine cleavage system
GN306_RS01115	COG0006	proline dipeptidase activity
GN306_RS01135	COG0572	uridine kinase
GN306_RS01140	COG1283	sodium-dependent phosphate transmembrane transporter activity
GN306_RS01145	COG1283	sodium-dependent phosphate transmembrane transporter activity
GN306_RS01155	COG0545	Peptidyl-prolyl cis-trans isomerase
GN306_RS01160	COG0545	Peptidyl-prolyl cis-trans isomerase
GN306_RS01165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GN306_RS01170	COG1773	rubredoxin
GN306_RS01175	COG1185	polyribonucleotide nucleotidyltransferase activity
GN306_RS01185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GN306_RS01315	COG3189	MarR family transcriptional regulator
GN306_RS01320	COG0439	Biotin carboxylase
GN306_RS01330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN306_RS01345	COG2096	Adenosyltransferase
GN306_RS01390	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GN306_RS01405	COG3645	SOS response
GN306_RS01410	COG4974	Belongs to the 'phage' integrase family
GN306_RS01440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GN306_RS01445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GN306_RS01450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GN306_RS01460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GN306_RS01465	COG1519	Transferase
GN306_RS01510	COG1022	Amp-dependent synthetase and ligase
GN306_RS01525	COG2954	triphosphatase activity
GN306_RS01545	COG0733	neurotransmitter:sodium symporter activity
GN306_RS01555	COG1785	Belongs to the alkaline phosphatase family
GN306_RS01575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GN306_RS01670	COG0551	DNA topoisomerase type I activity
GN306_RS01670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN306_RS01720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GN306_RS01740	COG1086	Polysaccharide biosynthesis protein
GN306_RS01755	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GN306_RS01790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GN306_RS01810	COG2205	protein histidine kinase activity
GN306_RS01810	COG0784	Response regulator, receiver
GN306_RS01845	COG1192	Involved in chromosome partitioning
GN306_RS01860	COG3385	transposase activity
GN306_RS02060	COG3385	transposase activity
GN306_RS02150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GN306_RS02155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GN306_RS02160	COG1663	tetraacyldisaccharide 4'-kinase activity
GN306_RS02165	COG0616	signal peptide processing
GN306_RS02215	COG0811	peptide transport
GN306_RS02245	COG1131	(ABC) transporter
GN306_RS02265	COG0534	Mate efflux family protein
GN306_RS02275	COG1187	pseudouridine synthase activity
GN306_RS02280	COG0017	Asparaginyl-tRNA synthetase
GN306_RS02300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GN306_RS02305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GN306_RS02310	COG0052	Belongs to the universal ribosomal protein uS2 family
GN306_RS02315	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GN306_RS02325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GN306_RS02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
GN306_RS02335	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GN306_RS02340	COG1575	Belongs to the MenA family. Type 1 subfamily
GN306_RS02345	COG1408	metallophosphoesterase
GN306_RS02355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GN306_RS02365	COG0194	GDP metabolic process
GN306_RS02375	COG1214	PFAM Peptidase M22, glycoprotease
GN306_RS02385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GN306_RS02390	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GN306_RS02395	COG0739	heme binding
GN306_RS02400	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GN306_RS02405	COG0750	zinc metalloprotease
GN306_RS02420	COG1272	protein, Hemolysin III
GN306_RS02425	COG0617	tRNA 3'-terminal CCA addition
GN306_RS02435	COG0632	four-way junction helicase activity
GN306_RS02440	COG0673	inositol 2-dehydrogenase activity
GN306_RS02445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GN306_RS02460	COG1621	beta-fructofuranosidase activity
GN306_RS02475	COG1105	Belongs to the carbohydrate kinase PfkB family
GN306_RS02480	COG3292	Two component regulator propeller
GN306_RS02480	COG2205	protein histidine kinase activity
GN306_RS02480	COG0745	RESPONSE REGULATOR receiver
GN306_RS02490	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GN306_RS02500	COG0254	rRNA binding
GN306_RS02505	COG0191	fructose-bisphosphate aldolase activity
GN306_RS02550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GN306_RS02550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GN306_RS02560	COG0563	adenylate kinase activity
GN306_RS02565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN306_RS02605	COG0138	bifunctional purine biosynthesis protein purh
GN306_RS02650	COG1482	cell wall glycoprotein biosynthetic process
GN306_RS02655	COG2706	6-phosphogluconolactonase activity
GN306_RS02670	COG0523	cobalamin synthesis protein
GN306_RS02685	COG4771	TonB-dependent receptor
GN306_RS02690	COG3292	Two component regulator propeller
GN306_RS02690	COG2205	protein histidine kinase activity
GN306_RS02690	COG0745	RESPONSE REGULATOR receiver
GN306_RS02710	COG2205	protein histidine kinase activity
GN306_RS02710	COG3437	response regulator, receiver
GN306_RS02710	COG3850	Histidine kinase
GN306_RS02710	COG4999	Histidine kinase
GN306_RS02715	COG5002	protein histidine kinase activity
GN306_RS02720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS02725	COG1007	ATP synthesis coupled electron transport
GN306_RS02730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN306_RS02735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GN306_RS02745	COG0839	Belongs to the complex I subunit 6 family
GN306_RS02750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN306_RS02755	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GN306_RS02760	COG0649	NAD binding
GN306_RS02765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN306_RS02770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN306_RS02775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GN306_RS02780	COG0569	domain protein
GN306_RS02785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GN306_RS02795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GN306_RS02810	COG3250	beta-galactosidase activity
GN306_RS02825	COG3119	arylsulfatase activity
GN306_RS02830	COG0702	epimerase
GN306_RS02835	COG4206	TonB-dependent receptor
GN306_RS02835	COG1629	transport
GN306_RS02860	COG3250	beta-galactosidase activity
GN306_RS02870	COG4771	TonB-dependent receptor
GN306_RS02935	COG0358	DNA primase activity
GN306_RS03015	COG3344	reverse transcriptase
GN306_RS03080	COG3385	transposase activity
GN306_RS03100	COG2205	protein histidine kinase activity
GN306_RS03100	COG2198	Histidine kinase
GN306_RS03100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS03100	COG0784	Response regulator, receiver
GN306_RS03120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN306_RS03120	COG0551	DNA topoisomerase type I activity
GN306_RS03155	COG4974	Belongs to the 'phage' integrase family
GN306_RS03195	COG1629	transport
GN306_RS03195	COG4206	TonB-dependent receptor
GN306_RS03220	COG3292	Two component regulator propeller
GN306_RS03220	COG2205	protein histidine kinase activity
GN306_RS03220	COG0745	RESPONSE REGULATOR receiver
GN306_RS03230	COG3250	beta-galactosidase activity
GN306_RS03235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS03245	COG3940	Belongs to the glycosyl hydrolase 43 family
GN306_RS03245	COG3940	Belongs to the glycosyl hydrolase 43 family
GN306_RS03260	COG1629	transport
GN306_RS03270	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS03285	COG2205	protein histidine kinase activity
GN306_RS03285	COG3292	Two component regulator propeller
GN306_RS03285	COG0745	RESPONSE REGULATOR receiver
GN306_RS03290	COG1012	belongs to the aldehyde dehydrogenase family
GN306_RS03315	COG2271	Major facilitator Superfamily
GN306_RS03320	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GN306_RS03325	COG3775	system Galactitol-specific IIC component
GN306_RS03330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS03335	COG4677	pectinesterase activity
GN306_RS03340	COG1629	transport
GN306_RS03350	COG0515	serine threonine protein kinase
GN306_RS03350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GN306_RS03355	COG4771	TonB-dependent receptor
GN306_RS03360	COG0702	epimerase
GN306_RS03365	COG3507	Belongs to the glycosyl hydrolase 43 family
GN306_RS03395	COG4771	TonB-dependent receptor
GN306_RS03425	COG1917	Cupin 2, conserved barrel domain protein
GN306_RS03440	COG2755	lipolytic protein G-D-S-L family
GN306_RS03445	COG0745	RESPONSE REGULATOR receiver
GN306_RS03445	COG2205	protein histidine kinase activity
GN306_RS03445	COG3292	Two component regulator propeller
GN306_RS03455	COG1506	peptidase
GN306_RS03455	COG0823	Involved in the tonB-independent uptake of proteins
GN306_RS03470	COG0138	bifunctional purine biosynthesis protein purh
GN306_RS03490	COG0768	penicillin binding
GN306_RS03495	COG0772	Belongs to the SEDS family
GN306_RS03505	COG1774	PSP1 C-terminal conserved region
GN306_RS03510	COG0470	DNA polymerase III
GN306_RS03515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GN306_RS03530	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GN306_RS03545	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GN306_RS03555	COG0628	permease
GN306_RS03560	COG1435	thymidine kinase activity
GN306_RS03565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GN306_RS03585	COG1629	transport
GN306_RS03595	COG1629	transport
GN306_RS03595	COG4206	TonB-dependent receptor
GN306_RS03600	COG4974	Belongs to the 'phage' integrase family
GN306_RS03605	COG1629	transport
GN306_RS03605	COG4206	TonB-dependent receptor
GN306_RS03620	COG4771	TonB-dependent receptor
GN306_RS03630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GN306_RS03645	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GN306_RS03645	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GN306_RS03655	COG0531	amino acid
GN306_RS03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GN306_RS03670	COG1566	PFAM secretion protein HlyD family protein
GN306_RS03680	COG1162	GTPase activity
GN306_RS03685	COG0233	cytoplasmic translational termination
GN306_RS03690	COG0406	alpha-ribazole phosphatase activity
GN306_RS03705	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS03710	COG0528	UMP kinase activity
GN306_RS03715	COG0534	Mate efflux family protein
GN306_RS03725	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GN306_RS03725	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GN306_RS03740	COG0792	nuclease activity
GN306_RS03760	COG1183	phosphatidylcholine synthase activity
GN306_RS03765	COG0688	phosphatidylethanolamine metabolic process
GN306_RS03795	COG0802	atpase or kinase
GN306_RS03800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GN306_RS03815	COG1830	Aldolase
GN306_RS03820	COG0588	phosphoglycerate mutase activity
GN306_RS03835	COG0475	glutathione-regulated potassium exporter activity
GN306_RS03910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GN306_RS03925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GN306_RS03930	COG0742	ribosomal rna small subunit methyltransferase
GN306_RS03945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GN306_RS03950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GN306_RS03955	COG0739	heme binding
GN306_RS03965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GN306_RS03970	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN306_RS03970	COG1388	LysM domain
GN306_RS03980	COG1475	DNA binding
GN306_RS03985	COG1192	Involved in chromosome partitioning
GN306_RS03990	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GN306_RS03995	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN306_RS04010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GN306_RS04025	COG1196	nuclear chromosome segregation
GN306_RS04030	COG2239	Acts as a magnesium transporter
GN306_RS04035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GN306_RS04045	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN306_RS04050	COG0590	tRNA wobble adenosine to inosine editing
GN306_RS04055	COG1396	sequence-specific DNA binding
GN306_RS04065	COG3550	peptidyl-serine autophosphorylation
GN306_RS04070	COG2373	Large extracellular alpha-helical protein
GN306_RS04090	COG0205	6-phosphofructokinase activity
GN306_RS04095	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GN306_RS04100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GN306_RS04115	COG0084	hydrolase, TatD family'
GN306_RS04125	COG0811	peptide transport
GN306_RS04155	COG1522	sequence-specific DNA binding
GN306_RS04170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GN306_RS04180	COG1595	DNA-templated transcription, initiation
GN306_RS04190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GN306_RS04190	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GN306_RS04215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GN306_RS04220	COG0538	isocitrate dehydrogenase activity
GN306_RS04225	COG0372	Belongs to the citrate synthase family
GN306_RS04240	COG1902	pentaerythritol trinitrate reductase activity
GN306_RS04270	COG0205	6-phosphofructokinase activity
GN306_RS04275	COG0546	phosphoglycolate phosphatase activity
GN306_RS04290	COG0511	ligase activity, forming carbon-carbon bonds
GN306_RS04295	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GN306_RS04300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS04310	COG0561	phosphatase activity
GN306_RS04315	COG4771	TonB-dependent receptor
GN306_RS04345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GN306_RS04365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GN306_RS04370	COG1506	peptidase
GN306_RS04370	COG0823	Involved in the tonB-independent uptake of proteins
GN306_RS04375	COG1242	4 iron, 4 sulfur cluster binding
GN306_RS04380	COG0426	domain, Protein
GN306_RS04385	COG0668	transmembrane transport
GN306_RS04390	COG0009	L-threonylcarbamoyladenylate synthase
GN306_RS04395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GN306_RS04455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN306_RS04460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GN306_RS04465	COG0066	3-isopropylmalate dehydratase activity
GN306_RS04470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN306_RS04475	COG0473	3-isopropylmalate dehydrogenase activity
GN306_RS04485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GN306_RS04495	COG0514	ATP-dependent DNA helicase (RecQ)
GN306_RS04515	COG0735	belongs to the Fur family
GN306_RS04520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GN306_RS04530	COG4771	TonB-dependent receptor
GN306_RS04545	COG2755	lipolytic protein G-D-S-L family
GN306_RS04560	COG4206	TonB-dependent receptor
GN306_RS04560	COG1629	transport
GN306_RS04565	COG0702	epimerase
GN306_RS04580	COG0488	(ABC) transporter
GN306_RS04585	COG3590	peptidase
GN306_RS04595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS04610	COG0673	inositol 2-dehydrogenase activity
GN306_RS04615	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GN306_RS04620	COG0826	peptidase U32
GN306_RS04630	COG4771	TonB-dependent receptor
GN306_RS04645	COG0095	Lipoate-protein ligase
GN306_RS04650	COG0508	dehydrogenase complex catalyzes the overall conversion of
GN306_RS04655	COG0022	dehydrogenase e1 component
GN306_RS04660	COG0716	FMN binding
GN306_RS04665	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GN306_RS04675	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GN306_RS04690	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GN306_RS04695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GN306_RS04700	COG1120	ATPase activity
GN306_RS04705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GN306_RS04730	COG1073	alpha beta
GN306_RS04750	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GN306_RS04755	COG0436	Aminotransferase
GN306_RS04765	COG1733	regulation of RNA biosynthetic process
GN306_RS04775	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GN306_RS04780	COG0628	permease
GN306_RS04790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS04795	COG0514	ATP-dependent DNA helicase (RecQ)
GN306_RS04800	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GN306_RS04800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GN306_RS04810	COG0006	proline dipeptidase activity
GN306_RS04825	COG1418	mRNA catabolic process
GN306_RS04840	COG2832	Protein of unknown function (DUF454)
GN306_RS04850	COG0602	queuosine metabolic process
GN306_RS04870	COG1115	amino acid carrier protein
GN306_RS04880	COG3292	Two component regulator propeller
GN306_RS04880	COG2205	protein histidine kinase activity
GN306_RS04880	COG0745	RESPONSE REGULATOR receiver
GN306_RS04890	COG3681	Belongs to the UPF0597 family
GN306_RS04995	COG4974	Belongs to the 'phage' integrase family
GN306_RS05005	COG2003	Belongs to the UPF0758 family
GN306_RS05100	COG3344	reverse transcriptase
GN306_RS05180	COG0210	DNA helicase
GN306_RS05200	COG0551	DNA topoisomerase type I activity
GN306_RS05200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN306_RS05240	COG0534	Mate efflux family protein
GN306_RS05270	COG0546	phosphoglycolate phosphatase activity
GN306_RS05280	COG2207	Transcriptional regulator
GN306_RS05305	COG4771	TonB-dependent receptor
GN306_RS05310	COG0702	epimerase
GN306_RS05315	COG3250	beta-galactosidase activity
GN306_RS05320	COG3292	Two component regulator propeller
GN306_RS05320	COG2205	protein histidine kinase activity
GN306_RS05320	COG0745	RESPONSE REGULATOR receiver
GN306_RS05345	COG4771	TonB-dependent receptor
GN306_RS05430	COG1629	transport
GN306_RS05430	COG4206	TonB-dependent receptor
GN306_RS05440	COG0126	phosphoglycerate kinase activity
GN306_RS05450	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS05470	COG0534	Mate efflux family protein
GN306_RS05475	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GN306_RS05480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GN306_RS05505	COG1629	transport
GN306_RS05515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS05520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS05535	COG3292	Two component regulator propeller
GN306_RS05535	COG2205	protein histidine kinase activity
GN306_RS05535	COG0745	RESPONSE REGULATOR receiver
GN306_RS05540	COG4771	TonB-dependent receptor
GN306_RS05595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GN306_RS05610	COG0321	lipoyl(octanoyl) transferase activity
GN306_RS05610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GN306_RS05615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GN306_RS05620	COG1834	amidinotransferase
GN306_RS05630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GN306_RS05640	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GN306_RS05700	COG4804	nuclease activity
GN306_RS05710	COG4413	Urea transporter
GN306_RS05715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GN306_RS05730	COG3591	Belongs to the peptidase S1B family
GN306_RS05735	COG3591	Belongs to the peptidase S1B family
GN306_RS05750	COG1408	metallophosphoesterase
GN306_RS05755	COG1410	methionine synthase
GN306_RS05755	COG0646	methionine synthase
GN306_RS05760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GN306_RS05765	COG0463	Glycosyl transferase, family 2
GN306_RS05810	COG2311	Membrane
GN306_RS05815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GN306_RS05825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GN306_RS05845	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GN306_RS05855	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GN306_RS05860	COG1032	radical SAM domain protein
GN306_RS05875	COG5434	Belongs to the glycosyl hydrolase 28 family
GN306_RS05905	COG2264	protein methyltransferase activity
GN306_RS05945	COG0673	inositol 2-dehydrogenase activity
GN306_RS05950	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GN306_RS06000	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GN306_RS06010	COG2160	L-arabinose isomerase activity
GN306_RS06035	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GN306_RS06055	COG0484	heat shock protein binding
GN306_RS06060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GN306_RS06065	COG0488	(ABC) transporter
GN306_RS06085	COG0393	Putative heavy-metal-binding
GN306_RS06125	COG1388	LysM domain
GN306_RS06125	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN306_RS06135	COG1136	(ABC) transporter
GN306_RS06140	COG0577	efflux transmembrane transporter activity
GN306_RS06150	COG1136	(ABC) transporter
GN306_RS06150	COG0577	efflux transmembrane transporter activity
GN306_RS06160	COG1136	(ABC) transporter
GN306_RS06160	COG0577	efflux transmembrane transporter activity
GN306_RS06185	COG2204	response regulator
GN306_RS06190	COG4191	Histidine kinase
GN306_RS06210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GN306_RS06215	COG0572	uridine kinase
GN306_RS06220	COG4974	Belongs to the 'phage' integrase family
GN306_RS06270	COG1484	DNA-dependent DNA replication
GN306_RS06350	COG0739	heme binding
GN306_RS06415	COG2198	Histidine kinase
GN306_RS06415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS06415	COG0784	Response regulator, receiver
GN306_RS06415	COG2205	protein histidine kinase activity
GN306_RS06425	COG0010	Belongs to the arginase family
GN306_RS06430	COG0058	SHG alpha-glucan phosphorylase activity
GN306_RS06435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GN306_RS06435	COG4651	solute:proton antiporter activity
GN306_RS06440	COG0205	6-phosphofructokinase activity
GN306_RS06455	COG0588	phosphoglycerate mutase activity
GN306_RS06460	COG1830	Aldolase
GN306_RS06470	COG2095	MarC family integral membrane protein
GN306_RS06505	COG0745	RESPONSE REGULATOR receiver
GN306_RS06505	COG3292	Two component regulator propeller
GN306_RS06505	COG2205	protein histidine kinase activity
GN306_RS06510	COG1629	transport
GN306_RS06515	COG0702	epimerase
GN306_RS06585	COG3292	Two component regulator propeller
GN306_RS06585	COG0745	RESPONSE REGULATOR receiver
GN306_RS06585	COG0745	RESPONSE REGULATOR receiver
GN306_RS06585	COG2205	protein histidine kinase activity
GN306_RS06585	COG2205	protein histidine kinase activity
GN306_RS06585	COG3292	Two component regulator propeller
GN306_RS06650	COG0622	Phosphoesterase
GN306_RS06700	COG3344	reverse transcriptase
GN306_RS06805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GN306_RS06810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GN306_RS06815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GN306_RS06820	COG0131	Imidazoleglycerol-phosphate dehydratase
GN306_RS06835	COG1773	rubredoxin
GN306_RS06835	COG1592	Rubrerythrin
GN306_RS06845	COG3118	belongs to the thioredoxin family
GN306_RS06860	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN306_RS06870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GN306_RS06875	COG0157	Belongs to the NadC ModD family
GN306_RS06880	COG3292	Two component regulator propeller
GN306_RS06880	COG2205	protein histidine kinase activity
GN306_RS06880	COG0745	RESPONSE REGULATOR receiver
GN306_RS06890	COG4771	TonB-dependent receptor
GN306_RS06905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GN306_RS06910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN306_RS06930	COG0443	Heat shock 70 kDa protein
GN306_RS06970	COG0110	maltose O-acetyltransferase activity
GN306_RS06990	COG1216	Glycosyl transferase, family 2
GN306_RS07005	COG0562	UDP-galactopyranose mutase
GN306_RS07055	COG0556	nucleotide-excision repair
GN306_RS07075	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS07085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GN306_RS07090	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GN306_RS07095	COG1169	isochorismate synthase
GN306_RS07100	COG2050	protein possibly involved in aromatic compounds catabolism
GN306_RS07105	COG0490	domain, Protein
GN306_RS07105	COG0471	metal ion transport
GN306_RS07110	COG0534	Mate efflux family protein
GN306_RS07115	COG0446	pyridine nucleotide-disulphide oxidoreductase
GN306_RS07130	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GN306_RS07140	COG4771	TonB-dependent receptor
GN306_RS07150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS07165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GN306_RS07170	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GN306_RS07180	COG0569	domain protein
GN306_RS07195	COG1760	l-serine dehydratase
GN306_RS07215	COG4771	TonB-dependent receptor
GN306_RS07240	COG2226	methyltransferase
GN306_RS07250	COG0582	viral genome integration into host DNA
GN306_RS07255	COG1193	negative regulation of DNA recombination
GN306_RS07280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GN306_RS07280	COG2755	lipolytic protein G-D-S-L family
GN306_RS07290	COG2217	Heavy metal translocating P-type atpase
GN306_RS07300	COG4221	oxidoreductase activity
GN306_RS07310	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GN306_RS07315	COG0511	ligase activity, forming carbon-carbon bonds
GN306_RS07325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN306_RS07340	COG0778	Nitroreductase
GN306_RS07355	COG0561	phosphatase activity
GN306_RS07360	COG0424	maF-like protein
GN306_RS07370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GN306_RS07385	COG2814	Major facilitator Superfamily
GN306_RS07390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS07395	COG1309	transcriptional regulator
GN306_RS07405	COG0596	Alpha beta hydrolase
GN306_RS07405	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GN306_RS07405	COG2226	methyltransferase
GN306_RS07410	COG1132	(ABC) transporter
GN306_RS07565	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GN306_RS07570	COG1410	methionine synthase
GN306_RS07570	COG0646	methionine synthase
GN306_RS07575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN306_RS07585	COG2233	PERMEase
GN306_RS07590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GN306_RS07605	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GN306_RS07605	COG0778	Nitroreductase
GN306_RS07615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GN306_RS07620	COG1704	LemA family
GN306_RS07635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GN306_RS07640	COG2226	methyltransferase
GN306_RS07645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GN306_RS07650	COG1702	phosphate starvation-inducible protein PhoH
GN306_RS07660	COG0101	tRNA pseudouridine synthase activity
GN306_RS07675	COG1047	Peptidyl-prolyl cis-trans
GN306_RS07685	COG0129	dihydroxy-acid dehydratase activity
GN306_RS07705	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GN306_RS07730	COG1253	flavin adenine dinucleotide binding
GN306_RS07750	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GN306_RS07765	COG0653	protein targeting
GN306_RS07795	COG0525	valine-tRNA ligase activity
GN306_RS07800	COG3956	TIGRFAM MazG family protein
GN306_RS07810	COG4771	TonB-dependent receptor
GN306_RS07825	COG1595	DNA-templated transcription, initiation
GN306_RS07830	COG1234	tRNA 3'-trailer cleavage
GN306_RS07850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GN306_RS07870	COG3275	phosphorelay sensor kinase activity
GN306_RS07905	COG1215	transferase activity, transferring glycosyl groups
GN306_RS07910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GN306_RS07920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GN306_RS07925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN306_RS07950	COG0738	Major facilitator superfamily
GN306_RS07955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GN306_RS07965	COG2204	response regulator
GN306_RS07985	COG0708	Exodeoxyribonuclease III
GN306_RS08000	COG1741	Belongs to the pirin family
GN306_RS08015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GN306_RS08025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GN306_RS08040	COG0793	Belongs to the peptidase S41A family
GN306_RS08045	COG2131	deaminase
GN306_RS08055	COG0339	signal peptide processing
GN306_RS08070	COG1477	protein flavinylation
GN306_RS08075	COG1971	Probably functions as a manganese efflux pump
GN306_RS08090	COG0463	Glycosyl transferase, family 2
GN306_RS08105	COG0514	ATP-dependent DNA helicase (RecQ)
GN306_RS08115	COG0148	phosphopyruvate hydratase activity
GN306_RS08125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS08135	COG3408	Glycogen debranching enzyme
GN306_RS08160	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GN306_RS08160	COG0662	Cupin 2, conserved barrel domain protein
GN306_RS08165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN306_RS08170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GN306_RS08190	COG1216	Glycosyl transferase, family 2
GN306_RS08195	COG0463	Glycosyl transferase, family 2
GN306_RS08210	COG0297	glycogen (starch) synthase activity
GN306_RS08230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN306_RS08245	COG1388	LysM domain
GN306_RS08245	COG4641	Protein conserved in bacteria
GN306_RS08300	COG3023	N-Acetylmuramoyl-L-alanine amidase
GN306_RS08375	COG3250	beta-galactosidase activity
GN306_RS08390	COG2985	domain, Protein
GN306_RS08390	COG0490	domain, Protein
GN306_RS08395	COG4206	TonB-dependent receptor
GN306_RS08395	COG1629	transport
GN306_RS08405	COG4771	TonB-dependent receptor
GN306_RS08415	COG3250	beta-galactosidase activity
GN306_RS08420	COG3250	beta-galactosidase activity
GN306_RS08425	COG3940	Belongs to the glycosyl hydrolase 43 family
GN306_RS08450	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN306_RS08455	COG0110	maltose O-acetyltransferase activity
GN306_RS08480	COG1216	Glycosyl transferase, family 2
GN306_RS08485	COG0438	transferase activity, transferring glycosyl groups
GN306_RS08490	COG1216	Glycosyl transferase, family 2
GN306_RS08495	COG0463	Glycosyl transferase, family 2
GN306_RS08500	COG0438	transferase activity, transferring glycosyl groups
GN306_RS08525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GN306_RS08525	COG0463	Glycosyl transferase, family 2
GN306_RS08530	COG1216	Glycosyl transferase, family 2
GN306_RS08540	COG1216	Glycosyl transferase, family 2
GN306_RS08595	COG3206	protein involved in exopolysaccharide biosynthesis
GN306_RS08595	COG0489	protein tyrosine kinase activity
GN306_RS08605	COG1132	(ABC) transporter
GN306_RS08655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GN306_RS08685	COG0598	Magnesium transport protein CorA
GN306_RS08690	COG1522	sequence-specific DNA binding
GN306_RS08700	COG0586	Pfam SNARE associated Golgi protein
GN306_RS08710	COG0306	phosphate transporter
GN306_RS08720	COG4771	TonB-dependent receptor
GN306_RS08730	COG2873	o-acetylhomoserine
GN306_RS08735	COG1620	l-lactate permease
GN306_RS08755	COG2205	protein histidine kinase activity
GN306_RS08780	COG0668	transmembrane transport
GN306_RS08785	COG0318	PFAM AMP-dependent synthetase and ligase
GN306_RS08795	COG0307	riboflavin synthase, alpha
GN306_RS08800	COG1295	ribonuclease BN
GN306_RS08825	COG0737	Belongs to the 5'-nucleotidase family
GN306_RS08835	COG4771	TonB-dependent receptor
GN306_RS08840	COG1509	lysine 2,3-aminomutase activity
GN306_RS08850	COG3408	Glycogen debranching enzyme
GN306_RS08865	COG0784	Response regulator, receiver
GN306_RS08865	COG2205	protein histidine kinase activity
GN306_RS08875	COG3059	membrane
GN306_RS08880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GN306_RS08885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GN306_RS08905	COG1914	H( )-stimulated, divalent metal cation uptake system
GN306_RS08910	COG3263	regulation of cellular component size
GN306_RS08915	COG0534	Mate efflux family protein
GN306_RS08925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GN306_RS08935	COG0488	(ABC) transporter
GN306_RS09010	COG0228	four-way junction DNA binding
GN306_RS09020	COG2755	lipolytic protein G-D-S-L family
GN306_RS09020	COG0657	acetylesterase activity
GN306_RS09045	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GN306_RS09050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GN306_RS09085	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GN306_RS09090	COG1333	cytochrome c biogenesis protein
GN306_RS09090	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GN306_RS09110	COG1730	sister chromatid segregation
GN306_RS09125	COG0438	transferase activity, transferring glycosyl groups
GN306_RS09140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GN306_RS09140	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN306_RS09145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GN306_RS09145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN306_RS09160	COG2226	methyltransferase
GN306_RS09175	COG0004	ammonium transporteR
GN306_RS09180	COG0347	Belongs to the P(II) protein family
GN306_RS09190	COG0436	Aminotransferase
GN306_RS09195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GN306_RS09200	COG1119	ATPase activity
GN306_RS09205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GN306_RS09210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GN306_RS09225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GN306_RS09230	COG0252	asparaginase activity
GN306_RS09260	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GN306_RS09265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GN306_RS09270	COG0363	glucosamine-6-phosphate deaminase activity
GN306_RS09280	COG1271	oxidase subunit
GN306_RS09295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS09300	COG1136	(ABC) transporter
GN306_RS09305	COG0577	efflux transmembrane transporter activity
GN306_RS09305	COG1136	(ABC) transporter
GN306_RS09315	COG3279	Response regulator of the LytR AlgR family
GN306_RS09330	COG4566	intracellular signal transduction
GN306_RS09335	COG0247	lactate metabolic process
GN306_RS09340	COG1139	Iron-sulfur cluster binding protein
GN306_RS09355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GN306_RS09380	COG0259	pyridoxamine-phosphate oxidase activity
GN306_RS09390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GN306_RS09390	COG1918	ferrous iron import across plasma membrane
GN306_RS09405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GN306_RS09410	COG0497	DNA recombination
GN306_RS09440	COG0297	glycogen (starch) synthase activity
GN306_RS09445	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GN306_RS09450	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GN306_RS09455	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GN306_RS09465	COG2816	NAD+ diphosphatase activity
GN306_RS09470	COG2183	response to ionizing radiation
GN306_RS09475	COG3250	beta-galactosidase activity
GN306_RS09480	COG0745	RESPONSE REGULATOR receiver
GN306_RS09480	COG2205	protein histidine kinase activity
GN306_RS09480	COG3292	Two component regulator propeller
GN306_RS09490	COG1629	transport
GN306_RS09490	COG4206	TonB-dependent receptor
GN306_RS09530	COG4771	TonB-dependent receptor
GN306_RS09545	COG1629	transport
GN306_RS09575	COG5012	cobalamin binding
GN306_RS09580	COG1501	Belongs to the glycosyl hydrolase 31 family
GN306_RS09595	COG0251	oxidation-reduction process
GN306_RS09620	COG0488	(ABC) transporter
GN306_RS09640	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GN306_RS09660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GN306_RS09665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GN306_RS09685	COG1215	transferase activity, transferring glycosyl groups
GN306_RS09690	COG0297	glycogen (starch) synthase activity
GN306_RS09745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GN306_RS09755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GN306_RS09770	COG1678	Uncharacterized ACR, COG1678
GN306_RS09780	COG2205	protein histidine kinase activity
GN306_RS09780	COG0745	RESPONSE REGULATOR receiver
GN306_RS09780	COG2205	protein histidine kinase activity
GN306_RS09780	COG3292	Two component regulator propeller
GN306_RS09780	COG0745	RESPONSE REGULATOR receiver
GN306_RS09780	COG3292	Two component regulator propeller
GN306_RS09790	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GN306_RS09795	COG1151	hydroxylamine reductase activity
GN306_RS09805	COG3119	arylsulfatase activity
GN306_RS09815	COG0745	RESPONSE REGULATOR receiver
GN306_RS09820	COG5002	protein histidine kinase activity
GN306_RS09840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GN306_RS09845	COG0248	Ppx GppA phosphatase
GN306_RS09855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GN306_RS09870	COG0356	it plays a direct role in the translocation of protons across the membrane
GN306_RS09875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN306_RS09880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GN306_RS09885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN306_RS09890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GN306_RS09895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GN306_RS09910	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GN306_RS09920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GN306_RS09925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GN306_RS09945	COG3973	AAA domain
GN306_RS09950	COG2855	membrane
GN306_RS09970	COG1979	alcohol dehydrogenase
GN306_RS09975	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GN306_RS09995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GN306_RS09995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GN306_RS10000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GN306_RS10005	COG0357	Ribosomal RNA small subunit methyltransferase G
GN306_RS10015	COG2217	Heavy metal translocating P-type atpase
GN306_RS10030	COG0321	lipoyl(octanoyl) transferase activity
GN306_RS10035	COG1022	Amp-dependent synthetase and ligase
GN306_RS10040	COG1252	NADH dehydrogenase
GN306_RS10070	COG3617	BRO family, N-terminal domain
GN306_RS10090	COG4974	Belongs to the 'phage' integrase family
GN306_RS10130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GN306_RS10135	COG1523	belongs to the glycosyl hydrolase 13 family
GN306_RS10140	COG1312	Catalyzes the dehydration of D-mannonate
GN306_RS10145	COG1752	Esterase of the alpha-beta hydrolase superfamily
GN306_RS10150	COG2176	DNA-directed DNA polymerase activity
GN306_RS10155	COG1739	Uncharacterized protein family UPF0029
GN306_RS10165	COG0556	nucleotide-excision repair
GN306_RS10190	COG3942	CHAP domain
GN306_RS10190	COG1388	LysM domain
GN306_RS10200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GN306_RS10205	COG3104	oligopeptide transport
GN306_RS10210	COG2431	L-lysine efflux transmembrane transporter activity
GN306_RS10225	COG1757	Na H antiporter
GN306_RS10230	COG2721	sulfolactate sulfo-lyase activity
GN306_RS10235	COG1609	Transcriptional regulator
GN306_RS10250	COG0501	Belongs to the peptidase M48B family
GN306_RS10260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GN306_RS10270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GN306_RS10285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GN306_RS10325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GN306_RS10340	COG1904	glucuronate isomerase
GN306_RS10345	COG0246	Mannitol dehydrogenase
GN306_RS10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GN306_RS10370	COG1120	ATPase activity
GN306_RS10375	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GN306_RS10405	COG0662	Cupin 2, conserved barrel domain protein
GN306_RS10405	COG2207	Transcriptional regulator
GN306_RS10410	COG2207	Transcriptional regulator
GN306_RS10410	COG4753	response regulator
GN306_RS10415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GN306_RS10425	COG4771	TonB-dependent receptor
GN306_RS10435	COG4771	TonB-dependent receptor
GN306_RS10440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GN306_RS10445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GN306_RS10450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GN306_RS10470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN306_RS10480	COG0439	Biotin carboxylase
GN306_RS10505	COG4771	TonB-dependent receptor
GN306_RS10510	COG4771	TonB-dependent receptor
GN306_RS10520	COG1797	cobyrinic acid a,c-diamide synthase activity
GN306_RS10525	COG2096	Adenosyltransferase
GN306_RS10530	COG1492	cobalamin metabolic process
GN306_RS10540	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GN306_RS10565	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GN306_RS10600	COG0513	Belongs to the DEAD box helicase family
GN306_RS10605	COG0560	Phosphoserine phosphatase
GN306_RS10605	COG3830	Belongs to the UPF0237 family
GN306_RS10615	COG1011	Hydrolase
GN306_RS10625	COG0343	queuine tRNA-ribosyltransferase activity
GN306_RS10630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GN306_RS10635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GN306_RS10640	COG1597	lipid kinase activity
GN306_RS10645	COG0156	8-amino-7-oxononanoate synthase activity
GN306_RS10660	COG1136	(ABC) transporter
GN306_RS10705	COG3852	Histidine kinase
GN306_RS10715	COG4771	TonB-dependent receptor
GN306_RS10735	COG2814	Major facilitator Superfamily
GN306_RS10785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GN306_RS10790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GN306_RS10830	COG3579	cysteine-type endopeptidase activity
GN306_RS10845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN306_RS10870	COG0728	peptidoglycan biosynthetic process
GN306_RS10880	COG1216	Glycosyl transferase, family 2
GN306_RS10880	COG1442	glycosyl transferase family 8
GN306_RS10890	COG1216	Glycosyl transferase, family 2
GN306_RS10900	COG0438	transferase activity, transferring glycosyl groups
GN306_RS10915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GN306_RS10945	COG1805	sodium ion transport
GN306_RS10950	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN306_RS10955	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN306_RS10960	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN306_RS10970	COG0513	Belongs to the DEAD box helicase family
GN306_RS10975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GN306_RS10980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GN306_RS10995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS11010	COG0561	phosphatase activity
GN306_RS11020	COG1285	pathogenesis
GN306_RS11030	COG2205	protein histidine kinase activity
GN306_RS11040	COG0494	nUDIX hydrolase
GN306_RS11050	COG1733	regulation of RNA biosynthetic process
GN306_RS11055	COG4106	trans-aconitate 2-methyltransferase activity
GN306_RS11070	COG3387	PFAM Glycoside hydrolase 15-related
GN306_RS11090	COG2205	protein histidine kinase activity
GN306_RS11090	COG2198	Histidine kinase
GN306_RS11090	COG0784	Response regulator, receiver
GN306_RS11090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS11115	COG0778	Nitroreductase
GN306_RS11150	COG4974	Belongs to the 'phage' integrase family
GN306_RS11170	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GN306_RS11175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GN306_RS11180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GN306_RS11190	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GN306_RS11195	COG2204	response regulator
GN306_RS11205	COG4176	ABC-type proline glycine betaine transport system permease component
GN306_RS11215	COG0697	spore germination
GN306_RS11220	COG0110	maltose O-acetyltransferase activity
GN306_RS11230	COG0024	Methionine aminopeptidase
GN306_RS11235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GN306_RS11245	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GN306_RS11250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GN306_RS11260	COG0552	protein localization to endoplasmic reticulum
GN306_RS11265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN306_RS11270	COG0776	regulation of translation
GN306_RS11275	COG0776	regulation of translation
GN306_RS11280	COG0714	Associated with various cellular activities
GN306_RS11295	COG2304	oxidoreductase activity
GN306_RS11320	COG0671	phosphoesterase, PA-phosphatase related
GN306_RS11345	COG0542	response to heat
GN306_RS11355	COG1752	Esterase of the alpha-beta hydrolase superfamily
GN306_RS11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GN306_RS11380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GN306_RS11385	COG0336	Belongs to the RNA methyltransferase TrmD family
GN306_RS11390	COG0167	dihydroorotate dehydrogenase activity
GN306_RS11395	COG0543	2 iron, 2 sulfur cluster binding
GN306_RS11410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GN306_RS11425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GN306_RS11435	COG0390	transport system, permease component
GN306_RS11440	COG1131	(ABC) transporter
GN306_RS11445	COG0442	prolyl-tRNA aminoacylation
GN306_RS11455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GN306_RS11485	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GN306_RS11505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS11510	COG1131	(ABC) transporter
GN306_RS11515	COG0842	Transport permease protein
GN306_RS11520	COG1129	ABC transporter
GN306_RS11520	COG0842	Transport permease protein
GN306_RS11525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GN306_RS11540	COG0540	Belongs to the ATCase OTCase family
GN306_RS11545	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GN306_RS11560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GN306_RS11565	COG0534	Mate efflux family protein
GN306_RS11570	COG2885	chlorophyll binding
GN306_RS11575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GN306_RS11610	COG0504	CTP synthase activity
GN306_RS11615	COG0706	membrane insertase activity
GN306_RS11620	COG0823	Involved in the tonB-independent uptake of proteins
GN306_RS11620	COG1506	peptidase
GN306_RS11625	COG0564	pseudouridine synthase activity
GN306_RS11630	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GN306_RS11635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GN306_RS11635	COG0574	Belongs to the PEP-utilizing enzyme family
GN306_RS11640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GN306_RS11655	COG1136	(ABC) transporter
GN306_RS11655	COG0577	efflux transmembrane transporter activity
GN306_RS11665	COG0339	signal peptide processing
GN306_RS11685	COG0438	transferase activity, transferring glycosyl groups
GN306_RS11715	COG1216	Glycosyl transferase, family 2
GN306_RS11735	COG0386	Belongs to the glutathione peroxidase family
GN306_RS11745	COG4191	Histidine kinase
GN306_RS11760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GN306_RS11765	COG0305	Participates in initiation and elongation during chromosome replication
GN306_RS11770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN306_RS11770	COG0072	phenylalanine-tRNA ligase activity
GN306_RS11775	COG0217	transcriptional regulatory protein
GN306_RS11795	COG0577	efflux transmembrane transporter activity
GN306_RS11800	COG1136	(ABC) transporter
GN306_RS11800	COG0577	efflux transmembrane transporter activity
GN306_RS11820	COG3852	Histidine kinase
GN306_RS11825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GN306_RS11825	COG3153	acetyltransferase
GN306_RS11885	COG0352	thiamine-phosphate diphosphorylase activity
GN306_RS11890	COG2022	thiamine diphosphate biosynthetic process
GN306_RS11895	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GN306_RS11915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GN306_RS11920	COG0754	glutathionylspermidine amidase activity
GN306_RS11930	COG0352	thiamine-phosphate diphosphorylase activity
GN306_RS11935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GN306_RS11940	COG4974	Belongs to the 'phage' integrase family
GN306_RS11945	COG0582	viral genome integration into host DNA
GN306_RS11950	COG4974	Belongs to the 'phage' integrase family
GN306_RS11960	COG1177	transmembrane transport
GN306_RS11985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS11990	COG0058	SHG alpha-glucan phosphorylase activity
GN306_RS12000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN306_RS12005	COG1269	ATP hydrolysis coupled proton transport
GN306_RS12020	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GN306_RS12070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS12105	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GN306_RS12110	COG1597	lipid kinase activity
GN306_RS12115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GN306_RS12125	COG1970	mechanosensitive ion channel activity
GN306_RS12130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GN306_RS12130	COG0519	Catalyzes the synthesis of GMP from XMP
GN306_RS12135	COG0519	Catalyzes the synthesis of GMP from XMP
GN306_RS12150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS12180	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS12195	COG3119	arylsulfatase activity
GN306_RS12240	COG4206	TonB-dependent receptor
GN306_RS12240	COG1629	transport
GN306_RS12260	COG1595	DNA-templated transcription, initiation
GN306_RS12265	COG1012	belongs to the aldehyde dehydrogenase family
GN306_RS12305	COG2211	Major facilitator Superfamily
GN306_RS12355	COG1408	metallophosphoesterase
GN306_RS12360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GN306_RS12375	COG1674	ftsk spoiiie
GN306_RS12385	COG0492	ferredoxin-NADP+ reductase activity
GN306_RS12390	COG0612	Peptidase, M16
GN306_RS12400	COG1131	(ABC) transporter
GN306_RS12405	COG0791	NLP P60 protein
GN306_RS12410	COG0546	phosphoglycolate phosphatase activity
GN306_RS12415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GN306_RS12420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GN306_RS12435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GN306_RS12445	COG0543	2 iron, 2 sulfur cluster binding
GN306_RS12465	COG0037	tRNA processing
GN306_RS12480	COG4864	UPF0365 protein
GN306_RS12485	COG0813	purine-nucleoside phosphorylase activity
GN306_RS12495	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GN306_RS12735	COG1388	LysM domain
GN306_RS12735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN306_RS12805	COG1196	nuclear chromosome segregation
GN306_RS12805	COG0741	lytic transglycosylase activity
GN306_RS12805	COG0739	heme binding
GN306_RS12825	COG3279	Response regulator of the LytR AlgR family
GN306_RS12855	COG0629	single-stranded DNA binding
GN306_RS12870	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GN306_RS12890	COG1192	Involved in chromosome partitioning
GN306_RS12905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GN306_RS13090	COG4974	Belongs to the 'phage' integrase family
GN306_RS13095	COG0582	viral genome integration into host DNA
GN306_RS13100	COG4974	Belongs to the 'phage' integrase family
GN306_RS13185	COG0202	RNA polymerase activity
GN306_RS13195	COG3344	reverse transcriptase
GN306_RS13250	COG4974	Belongs to the 'phage' integrase family
GN306_RS13265	COG3344	reverse transcriptase
GN306_RS13290	COG4771	TonB-dependent receptor
GN306_RS13355	COG1063	alcohol dehydrogenase
GN306_RS13370	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS13375	COG0346	lactoylglutathione lyase activity
GN306_RS13390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GN306_RS13415	COG0564	pseudouridine synthase activity
GN306_RS13420	COG0534	Mate efflux family protein
GN306_RS13440	COG1538	Outer membrane efflux protein
GN306_RS13520	COG3279	Response regulator of the LytR AlgR family
GN306_RS13525	COG3275	phosphorelay sensor kinase activity
GN306_RS13540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GN306_RS13550	COG0739	heme binding
GN306_RS13555	COG0686	Belongs to the AlaDH PNT family
GN306_RS13560	COG0805	protein transport
GN306_RS13565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GN306_RS13585	COG2855	membrane
GN306_RS13590	COG0583	DNA-binding transcription factor activity
GN306_RS13600	COG0542	response to heat
GN306_RS13620	COG1862	Preprotein translocase
GN306_RS13625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GN306_RS13635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GN306_RS13640	COG0193	aminoacyl-tRNA hydrolase activity
GN306_RS13645	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GN306_RS13655	COG4651	solute:proton antiporter activity
GN306_RS13655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GN306_RS13660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GN306_RS13665	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN306_RS13670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GN306_RS13675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GN306_RS13685	COG2205	protein histidine kinase activity
GN306_RS13685	COG0745	RESPONSE REGULATOR receiver
GN306_RS13685	COG3292	Two component regulator propeller
GN306_RS13700	COG5146	pantothenate kinase activity
GN306_RS13770	COG0656	L-ascorbic acid biosynthetic process
GN306_RS13775	COG0656	L-ascorbic acid biosynthetic process
GN306_RS13780	COG0656	L-ascorbic acid biosynthetic process
GN306_RS13785	COG3250	beta-galactosidase activity
GN306_RS13845	COG0805	protein transport
GN306_RS13850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GN306_RS13865	COG0655	NAD(P)H dehydrogenase (quinone) activity
GN306_RS13890	COG0667	Aldo Keto reductase
GN306_RS13895	COG2311	Membrane
GN306_RS13900	COG0697	spore germination
GN306_RS13915	COG0667	Aldo Keto reductase
GN306_RS13920	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS13950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GN306_RS13955	COG0534	Mate efflux family protein
GN306_RS13980	COG0656	L-ascorbic acid biosynthetic process
GN306_RS13990	COG0667	Aldo Keto reductase
GN306_RS14010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GN306_RS14095	COG2815	serine threonine protein kinase
GN306_RS14095	COG0515	serine threonine protein kinase
GN306_RS14200	COG4474	Belongs to the UPF0398 family
GN306_RS14240	COG4974	Belongs to the 'phage' integrase family
GN306_RS14245	COG4974	Belongs to the 'phage' integrase family
GN306_RS14295	COG2204	response regulator
GN306_RS14300	COG0784	Response regulator, receiver
GN306_RS14300	COG2198	Histidine kinase
GN306_RS14300	COG5002	protein histidine kinase activity
GN306_RS14305	COG0805	protein transport
GN306_RS14310	COG1472	Belongs to the glycosyl hydrolase 3 family
GN306_RS14320	COG2942	2-epimerase
GN306_RS14325	COG2211	Major facilitator Superfamily
GN306_RS14330	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GN306_RS14335	COG4124	Belongs to the glycosyl hydrolase 26 family
GN306_RS14345	COG0702	epimerase
GN306_RS14350	COG4771	TonB-dependent receptor
GN306_RS14355	COG3458	cephalosporin-C deacetylase activity
GN306_RS14400	COG0788	formyltetrahydrofolate deformylase activity
GN306_RS14410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GN306_RS14415	COG0107	imidazoleglycerol-phosphate synthase activity
GN306_RS14420	COG0140	phosphoribosyl-ATP diphosphatase activity
GN306_RS14420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GN306_RS14425	COG2884	Cell division ATP-binding protein ftsE
GN306_RS14430	COG0527	aspartate kinase activity
GN306_RS14435	COG0019	diaminopimelate decarboxylase activity
GN306_RS14460	COG2431	L-lysine efflux transmembrane transporter activity
GN306_RS14470	COG0436	Aminotransferase
GN306_RS14485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GN306_RS14490	COG0167	dihydroorotate dehydrogenase activity
GN306_RS14540	COG1027	Aspartate ammonia-lyase
GN306_RS14545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GN306_RS14555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GN306_RS14565	COG4657	Part of a membrane complex involved in electron transport
GN306_RS14570	COG4660	Part of a membrane complex involved in electron transport
GN306_RS14575	COG4659	FMN binding
GN306_RS14580	COG4658	electron transport chain
GN306_RS14585	COG4656	Part of a membrane complex involved in electron transport
GN306_RS14600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GN306_RS14605	COG0697	spore germination
GN306_RS14615	COG0076	glutamate decarboxylase activity
GN306_RS14620	COG2066	Belongs to the glutaminase family
GN306_RS14625	COG3142	Participates in the control of copper homeostasis
GN306_RS14640	COG0531	amino acid
GN306_RS14645	COG5002	protein histidine kinase activity
GN306_RS14650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GN306_RS14655	COG0481	GTPase activity
GN306_RS14675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GN306_RS14680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GN306_RS14745	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GN306_RS14750	COG0297	glycogen (starch) synthase activity
GN306_RS14775	COG3754	Rhamnan synthesis protein F
GN306_RS14790	COG0438	transferase activity, transferring glycosyl groups
GN306_RS14795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GN306_RS14845	COG4974	Belongs to the 'phage' integrase family
GN306_RS14985	COG3344	reverse transcriptase
GN306_RS15140	COG3196	Protein conserved in bacteria
GN306_RS15145	COG4974	Belongs to the 'phage' integrase family
GN306_RS15165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN306_RS15165	COG0551	DNA topoisomerase type I activity
GN306_RS15180	COG4804	nuclease activity
GN306_RS15210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GN306_RS15215	COG0581	inorganic phosphate transmembrane transporter activity
GN306_RS15220	COG0573	inorganic phosphate transmembrane transporter activity
GN306_RS15225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GN306_RS15230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GN306_RS15245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GN306_RS15250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN306_RS15255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GN306_RS15265	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN306_RS15290	COG2115	Belongs to the xylose isomerase family
GN306_RS15305	COG0745	RESPONSE REGULATOR receiver
GN306_RS15305	COG3292	Two component regulator propeller
GN306_RS15305	COG2205	protein histidine kinase activity
GN306_RS15310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN306_RS15330	COG1215	transferase activity, transferring glycosyl groups
GN306_RS15355	COG1216	Glycosyl transferase, family 2
GN306_RS15360	COG1216	Glycosyl transferase, family 2
GN306_RS15380	COG0438	transferase activity, transferring glycosyl groups
GN306_RS15390	COG1215	transferase activity, transferring glycosyl groups
GN306_RS15410	COG0438	transferase activity, transferring glycosyl groups
GN306_RS15420	COG1216	Glycosyl transferase, family 2
GN306_RS15420	COG1442	glycosyl transferase family 8
GN306_RS15425	COG0438	transferase activity, transferring glycosyl groups
GN306_RS15430	COG0463	Glycosyl transferase, family 2
GN306_RS15435	COG0745	RESPONSE REGULATOR receiver
GN306_RS15440	COG2205	protein histidine kinase activity
GN306_RS15440	COG0784	Response regulator, receiver
GN306_RS15455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN306_RS15460	COG0352	thiamine-phosphate diphosphorylase activity
GN306_RS15460	COG0351	phosphomethylpyrimidine kinase
GN306_RS15465	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GN306_RS15475	COG0366	Alpha amylase catalytic
GN306_RS15490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GN306_RS15495	COG0071	Belongs to the small heat shock protein (HSP20) family
GN306_RS15510	COG0505	Belongs to the CarA family
GN306_RS15520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GN306_RS15525	COG0070	glutamate synthase
GN306_RS15525	COG0067	glutamate synthase
GN306_RS15525	COG0069	glutamate synthase activity
GN306_RS15535	COG0367	asparagine synthase
GN306_RS15580	COG5433	transposase activity
GN306_RS15600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GN306_RS15615	COG0438	transferase activity, transferring glycosyl groups
GN306_RS15635	COG0438	transferase activity, transferring glycosyl groups
GN306_RS15675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN306_RS15735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GN306_RS15745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GN306_RS15750	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GN306_RS15755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GN306_RS15760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GN306_RS15770	COG0242	peptide deformylase activity
GN306_RS15775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GN306_RS15820	COG1506	peptidase
GN306_RS15820	COG0823	Involved in the tonB-independent uptake of proteins
GN306_RS15820	COG4946	Tricorn protease homolog
GN306_RS15825	COG0477	Major facilitator Superfamily
GN306_RS15825	COG2814	Major facilitator Superfamily
GN306_RS15850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS15880	COG0133	tryptophan synthase activity
GN306_RS15885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GN306_RS15890	COG0512	Glutamine amidotransferase of anthranilate synthase
GN306_RS15895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GN306_RS15900	COG0134	indole-3-glycerol-phosphate synthase activity
GN306_RS15905	COG0135	phosphoribosylanthranilate isomerase activity
GN306_RS15910	COG0159	tryptophan synthase activity
GN306_RS15915	COG0252	asparaginase activity
GN306_RS15920	COG0745	RESPONSE REGULATOR receiver
GN306_RS15925	COG5002	protein histidine kinase activity
GN306_RS15940	COG0629	single-stranded DNA binding
GN306_RS15950	COG0776	regulation of translation
GN306_RS15955	COG1530	ribonuclease E activity
GN306_RS15965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN306_RS15975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GN306_RS15980	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GN306_RS15985	COG0166	Belongs to the GPI family
GN306_RS15990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GN306_RS16000	COG0702	epimerase
GN306_RS16005	COG4771	TonB-dependent receptor
GN306_RS16020	COG1940	carbohydrate kinase activity
GN306_RS16035	COG2271	Major facilitator Superfamily
GN306_RS16040	COG0363	glucosamine-6-phosphate deaminase activity
GN306_RS16045	COG0363	glucosamine-6-phosphate deaminase activity
GN306_RS16055	COG4977	sequence-specific DNA binding
GN306_RS16055	COG1917	Cupin 2, conserved barrel domain protein
GN306_RS16060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS16120	COG0745	RESPONSE REGULATOR receiver
GN306_RS16130	COG3250	beta-galactosidase activity
GN306_RS16140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS16150	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS16170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS16185	COG1629	transport
GN306_RS16185	COG4206	TonB-dependent receptor
GN306_RS16195	COG2502	aspartate--ammonia ligase
GN306_RS16200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GN306_RS16215	COG3876	Protein conserved in bacteria
GN306_RS16230	COG1132	(ABC) transporter
GN306_RS16250	COG0732	type I restriction modification DNA specificity domain
GN306_RS16260	COG0732	type I restriction modification DNA specificity domain
GN306_RS16270	COG4974	Belongs to the 'phage' integrase family
GN306_RS16275	COG0582	viral genome integration into host DNA
GN306_RS16280	COG4974	Belongs to the 'phage' integrase family
GN306_RS16290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GN306_RS16365	COG0860	N-Acetylmuramoyl-L-alanine amidase
GN306_RS16375	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GN306_RS16380	COG0778	Nitroreductase
GN306_RS16395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GN306_RS16410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN306_RS16415	COG0318	PFAM AMP-dependent synthetase and ligase
GN306_RS16425	COG0359	binds to the 23S rRNA
GN306_RS16430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GN306_RS16435	COG0360	Binds together with S18 to 16S ribosomal RNA
GN306_RS16460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GN306_RS16465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GN306_RS16515	COG3661	Belongs to the glycosyl hydrolase 67 family
GN306_RS16525	COG3507	Belongs to the glycosyl hydrolase 43 family
GN306_RS16530	COG0745	RESPONSE REGULATOR receiver
GN306_RS16530	COG2205	protein histidine kinase activity
GN306_RS16530	COG3292	Two component regulator propeller
GN306_RS16540	COG1629	transport
GN306_RS16540	COG4206	TonB-dependent receptor
GN306_RS16545	COG3507	Belongs to the glycosyl hydrolase 43 family
GN306_RS16560	COG2211	Major facilitator Superfamily
GN306_RS16570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GN306_RS16580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GN306_RS16585	COG0658	competence protein
GN306_RS16585	COG2333	competence protein COMEC
GN306_RS16590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GN306_RS16610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GN306_RS16620	COG0009	L-threonylcarbamoyladenylate synthase
GN306_RS16675	COG0745	RESPONSE REGULATOR receiver
GN306_RS16675	COG2205	protein histidine kinase activity
GN306_RS16675	COG0745	RESPONSE REGULATOR receiver
GN306_RS16675	COG3292	Two component regulator propeller
GN306_RS16675	COG3292	Two component regulator propeller
GN306_RS16675	COG2205	protein histidine kinase activity
GN306_RS16680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GN306_RS16715	COG0681	Belongs to the peptidase S26 family
GN306_RS16780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GN306_RS16795	COG1280	lysine exporter protein (LysE YggA)
GN306_RS16800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GN306_RS16800	COG0047	phosphoribosylformylglycinamidine synthase activity
GN306_RS16805	COG0745	RESPONSE REGULATOR receiver
GN306_RS16805	COG2205	protein histidine kinase activity
GN306_RS16805	COG3292	Two component regulator propeller
GN306_RS16810	COG2059	Chromate
GN306_RS16825	COG1501	Belongs to the glycosyl hydrolase 31 family
GN306_RS16830	COG1649	PFAM Uncharacterised BCR, COG1649
GN306_RS16845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS16860	COG1966	Carbon starvation protein
GN306_RS16870	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GN306_RS16875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GN306_RS16880	COG0284	orotidine-5'-phosphate decarboxylase activity
GN306_RS16885	COG1078	dGTPase activity
GN306_RS16890	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN306_RS16895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GN306_RS16895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GN306_RS16900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN306_RS16910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GN306_RS16930	COG0386	Belongs to the glutathione peroxidase family
GN306_RS16940	COG4206	TonB-dependent receptor
GN306_RS16940	COG1629	transport
GN306_RS16950	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS16960	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS16975	COG2267	carboxylic ester hydrolase activity
GN306_RS17030	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS17045	COG1629	transport
GN306_RS17070	COG1472	Belongs to the glycosyl hydrolase 3 family
GN306_RS17080	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS17090	COG0702	epimerase
GN306_RS17095	COG1629	transport
GN306_RS17105	COG1082	Xylose isomerase domain protein TIM barrel
GN306_RS17115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS17120	COG0745	RESPONSE REGULATOR receiver
GN306_RS17120	COG2205	protein histidine kinase activity
GN306_RS17120	COG3292	Two component regulator propeller
GN306_RS17145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN306_RS17145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN306_RS17150	COG0436	Aminotransferase
GN306_RS17160	COG1472	Belongs to the glycosyl hydrolase 3 family
GN306_RS17165	COG0737	Belongs to the 5'-nucleotidase family
GN306_RS17170	COG0737	Belongs to the 5'-nucleotidase family
GN306_RS17175	COG0335	large ribosomal subunit rRNA binding
GN306_RS17180	COG3292	Two component regulator propeller
GN306_RS17180	COG0745	RESPONSE REGULATOR receiver
GN306_RS17180	COG2205	protein histidine kinase activity
GN306_RS17185	COG3254	rhamnose metabolic process
GN306_RS17190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN306_RS17195	COG3401	FG-GAP repeat protein
GN306_RS17225	COG0702	epimerase
GN306_RS17230	COG4771	TonB-dependent receptor
GN306_RS17255	COG2755	lipolytic protein G-D-S-L family
GN306_RS17260	COG3401	FG-GAP repeat protein
GN306_RS17265	COG3250	beta-galactosidase activity
GN306_RS17275	COG3119	arylsulfatase activity
GN306_RS17290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN306_RS17295	COG4206	TonB-dependent receptor
GN306_RS17295	COG1629	transport
GN306_RS17310	COG4206	TonB-dependent receptor
GN306_RS17310	COG1629	transport
GN306_RS17320	COG4771	TonB-dependent receptor
GN306_RS17330	COG4771	TonB-dependent receptor
GN306_RS17355	COG3401	FG-GAP repeat protein
GN306_RS17370	COG1874	Beta-galactosidase
GN306_RS17380	COG3250	beta-galactosidase activity
GN306_RS17385	COG2755	lipolytic protein G-D-S-L family
GN306_RS17425	COG3254	rhamnose metabolic process
GN306_RS17430	COG1940	carbohydrate kinase activity
GN306_RS17440	COG0577	efflux transmembrane transporter activity
GN306_RS17440	COG1136	(ABC) transporter
GN306_RS17445	COG1136	(ABC) transporter
GN306_RS17445	COG0577	efflux transmembrane transporter activity
GN306_RS17465	COG2996	Protein conserved in bacteria
GN306_RS17470	COG1979	alcohol dehydrogenase
GN306_RS17480	COG1136	(ABC) transporter
GN306_RS17485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GN306_RS17490	COG0589	response to stress
GN306_RS17490	COG0475	glutathione-regulated potassium exporter activity
GN306_RS17495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GN306_RS17505	COG0423	glycine-tRNA ligase activity
GN306_RS17560	COG0561	phosphatase activity
GN306_RS17565	COG4771	TonB-dependent receptor
GN306_RS17570	COG2207	Transcriptional regulator
GN306_RS17585	COG0738	Major facilitator superfamily
GN306_RS17590	COG1063	alcohol dehydrogenase
GN306_RS17595	COG2095	MarC family integral membrane protein
GN306_RS17630	COG1696	Membrane protein involved in D-alanine export
GN306_RS17655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS17685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS17695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GN306_RS17735	COG3969	phosphoadenosine phosphosulfate
GN306_RS17740	COG1475	DNA binding
GN306_RS17750	COG0039	L-malate dehydrogenase activity
GN306_RS17765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS17780	COG3015	lipoprotein NlpE involved in copper resistance
GN306_RS17795	COG0489	protein tyrosine kinase activity
GN306_RS17810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GN306_RS17815	COG1722	exodeoxyribonuclease VII activity
GN306_RS17820	COG1570	exodeoxyribonuclease VII activity
GN306_RS17830	COG0534	Mate efflux family protein
GN306_RS17890	COG0641	radical SAM
GN306_RS17970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GN306_RS17980	COG1088	dTDP-glucose 4,6-dehydratase activity
GN306_RS17985	COG1629	transport
GN306_RS17995	COG3250	beta-galactosidase activity
GN306_RS18000	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GN306_RS18000	COG3408	Glycogen debranching enzyme
GN306_RS18005	COG0702	epimerase
GN306_RS18010	COG4771	TonB-dependent receptor
GN306_RS18025	COG0488	(ABC) transporter
GN306_RS18030	COG2985	domain, Protein
GN306_RS18030	COG0569	domain protein
GN306_RS18035	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN306_RS18040	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN306_RS18040	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN306_RS18050	COG1629	transport
GN306_RS18060	COG4206	TonB-dependent receptor
GN306_RS18060	COG1629	transport
GN306_RS18065	COG2205	protein histidine kinase activity
GN306_RS18070	COG0668	transmembrane transport
GN306_RS18105	COG2086	electron transfer activity
GN306_RS18110	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GN306_RS18130	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GN306_RS18140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GN306_RS18155	COG4974	Belongs to the 'phage' integrase family
GN306_RS18160	COG0582	viral genome integration into host DNA
GN306_RS18165	COG4974	Belongs to the 'phage' integrase family
GN306_RS18185	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GN306_RS18195	COG1228	amidohydrolase
GN306_RS18200	COG3404	Formiminotransferase-cyclodeaminase
GN306_RS18205	COG2986	histidine ammonia-lyase
GN306_RS18210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GN306_RS18220	COG0693	protein deglycase activity
GN306_RS18240	COG0673	inositol 2-dehydrogenase activity
GN306_RS18245	COG0288	reversible hydration of carbon dioxide
GN306_RS18265	COG0459	protein refolding
GN306_RS18270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GN306_RS18280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN306_RS18290	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GN306_RS18295	COG0124	histidyl-tRNA synthetase
GN306_RS18300	COG1879	ABC-type sugar transport system periplasmic component
GN306_RS18315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GN306_RS18320	COG3958	Transketolase
GN306_RS18325	COG3959	Transketolase, thiamine diphosphate binding domain
GN306_RS18330	COG1349	DNA-binding transcription factor activity
GN306_RS18335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN306_RS18335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN306_RS18345	COG0745	RESPONSE REGULATOR receiver
GN306_RS18345	COG3292	Two component regulator propeller
GN306_RS18345	COG2205	protein histidine kinase activity
GN306_RS18345	COG0745	RESPONSE REGULATOR receiver
GN306_RS18345	COG2205	protein histidine kinase activity
GN306_RS18345	COG3292	Two component regulator propeller
GN306_RS18355	COG1629	transport
GN306_RS18415	COG4206	TonB-dependent receptor
GN306_RS18425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GN306_RS18435	COG0534	Mate efflux family protein
GN306_RS18440	COG2198	Histidine kinase
GN306_RS18440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS18440	COG2205	protein histidine kinase activity
GN306_RS18440	COG0784	Response regulator, receiver
GN306_RS18445	COG2204	response regulator
GN306_RS18455	COG0564	pseudouridine synthase activity
GN306_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS18475	COG3250	beta-galactosidase activity
GN306_RS18495	COG4206	TonB-dependent receptor
GN306_RS18495	COG1629	transport
GN306_RS18500	COG0513	Belongs to the DEAD box helicase family
GN306_RS18520	COG0482	sulfurtransferase activity
GN306_RS18525	COG2197	response regulator
GN306_RS18555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GN306_RS18570	COG3022	response to hydroperoxide
GN306_RS18575	COG2885	chlorophyll binding
GN306_RS18585	COG2895	sulfate adenylyltransferase (ATP) activity
GN306_RS18590	COG0175	sulfate reduction
GN306_RS18595	COG0529	Catalyzes the synthesis of activated sulfate
GN306_RS18600	COG0471	metal ion transport
GN306_RS18600	COG3273	potassium ion transport
GN306_RS18605	COG1218	3'(2'),5'-bisphosphate nucleotidase
GN306_RS18615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GN306_RS18645	COG0517	IMP dehydrogenase activity
GN306_RS18645	COG0516	GMP reductase activity
GN306_RS18655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GN306_RS18660	COG0740	serine-type endopeptidase activity
GN306_RS18665	COG0544	peptidyl-prolyl cis-trans isomerase activity
GN306_RS18670	COG0724	RNA recognition motif
GN306_RS18680	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GN306_RS18685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GN306_RS18690	COG1160	GTP binding
GN306_RS18695	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GN306_RS18700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GN306_RS18755	COG0039	L-malate dehydrogenase activity
GN306_RS18760	COG0358	DNA primase activity
GN306_RS18765	COG0302	gtp cyclohydrolase
GN306_RS18785	COG0739	heme binding
GN306_RS18790	COG0105	UTP biosynthetic process
GN306_RS18795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GN306_RS18800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GN306_RS18815	COG0848	biopolymer transport protein
GN306_RS18820	COG0811	peptide transport
GN306_RS18825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GN306_RS18830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GN306_RS18860	COG0420	3'-5' exonuclease activity
GN306_RS18870	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN306_RS18875	COG4206	TonB-dependent receptor
GN306_RS18875	COG1629	transport
GN306_RS18880	COG4977	sequence-specific DNA binding
GN306_RS18900	COG3408	Glycogen debranching enzyme
GN306_RS18905	COG0702	epimerase
GN306_RS18910	COG4771	TonB-dependent receptor
GN306_RS18925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GN306_RS18930	COG4771	TonB-dependent receptor
GN306_RS18935	COG0702	epimerase
GN306_RS18950	COG3507	Belongs to the glycosyl hydrolase 43 family
GN306_RS18960	COG4771	TonB-dependent receptor
GN306_RS18970	COG1629	transport
GN306_RS18970	COG4206	TonB-dependent receptor
GN306_RS18975	COG3292	Two component regulator propeller
GN306_RS18975	COG2205	protein histidine kinase activity
GN306_RS18975	COG0745	RESPONSE REGULATOR receiver
GN306_RS18995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GN306_RS19000	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GN306_RS19005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GN306_RS19020	COG1346	cytolysis
GN306_RS19030	COG0280	phosphate acetyltransferase
GN306_RS19035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GN306_RS19040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN306_RS19045	COG2151	metal-sulfur cluster biosynthetic enzyme
GN306_RS19050	COG2003	Belongs to the UPF0758 family
GN306_RS19055	COG0463	Glycosyl transferase, family 2
GN306_RS19055	COG1216	Glycosyl transferase, family 2
GN306_RS19060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GN306_RS19065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GN306_RS19070	COG0641	radical SAM
GN306_RS19100	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN306_RS19105	COG3119	arylsulfatase activity
GN306_RS19110	COG0702	epimerase
GN306_RS19115	COG4771	TonB-dependent receptor
GN306_RS19120	COG0657	acetylesterase activity
GN306_RS19120	COG2755	lipolytic protein G-D-S-L family
GN306_RS19125	COG0745	RESPONSE REGULATOR receiver
GN306_RS19125	COG2205	protein histidine kinase activity
GN306_RS19125	COG3292	Two component regulator propeller
GN306_RS19145	COG0564	pseudouridine synthase activity
GN306_RS19150	COG1181	Belongs to the D-alanine--D-alanine ligase family
GN306_RS19170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GN306_RS19175	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GN306_RS19180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GN306_RS19185	COG0561	phosphatase activity
GN306_RS19210	COG4206	TonB-dependent receptor
GN306_RS19210	COG1629	transport
GN306_RS19220	COG4771	TonB-dependent receptor
GN306_RS19230	COG1629	transport
GN306_RS19230	COG4206	TonB-dependent receptor
GN306_RS19250	COG4974	Belongs to the 'phage' integrase family
GN306_RS19255	COG0582	viral genome integration into host DNA
GN306_RS19260	COG4974	Belongs to the 'phage' integrase family
GN306_RS19265	COG4206	TonB-dependent receptor
GN306_RS19265	COG1629	transport
GN306_RS19280	COG1629	transport
GN306_RS19280	COG4206	TonB-dependent receptor
GN306_RS19295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GN306_RS19300	COG1917	Cupin 2, conserved barrel domain protein
GN306_RS19300	COG1396	sequence-specific DNA binding
GN306_RS19315	COG0348	domain, Protein
GN306_RS19325	COG1368	sulfuric ester hydrolase activity
GN306_RS19330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GN306_RS19335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GN306_RS19340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GN306_RS19345	COG0137	argininosuccinate synthase activity
GN306_RS19355	COG1438	arginine binding
GN306_RS19360	COG1070	Carbohydrate kinase
GN306_RS19365	COG4806	L-rhamnose isomerase
GN306_RS19375	COG0235	Class ii aldolase
GN306_RS19390	COG0702	epimerase
GN306_RS19395	COG4206	TonB-dependent receptor
GN306_RS19395	COG1629	transport
GN306_RS19400	COG2205	protein histidine kinase activity
GN306_RS19400	COG0745	RESPONSE REGULATOR receiver
GN306_RS19400	COG3292	Two component regulator propeller
GN306_RS19410	COG1388	LysM domain
GN306_RS19410	COG0741	lytic transglycosylase activity
GN306_RS19415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GN306_RS19420	COG3250	beta-galactosidase activity
GN306_RS19440	COG0673	inositol 2-dehydrogenase activity
GN306_RS19455	COG0656	L-ascorbic acid biosynthetic process
GN306_RS19460	COG0656	L-ascorbic acid biosynthetic process
GN306_RS19465	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS19470	COG2249	NAD(P)H dehydrogenase (quinone) activity
GN306_RS19475	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GN306_RS19485	COG1082	Xylose isomerase domain protein TIM barrel
GN306_RS19495	COG4974	Belongs to the 'phage' integrase family
GN306_RS19500	COG0582	viral genome integration into host DNA
GN306_RS19505	COG4974	Belongs to the 'phage' integrase family
GN306_RS19525	COG4771	TonB-dependent receptor
GN306_RS19530	COG3537	Alpha-1,2-mannosidase
GN306_RS19560	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GN306_RS19565	COG0542	response to heat
GN306_RS19570	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GN306_RS19580	COG0534	Mate efflux family protein
GN306_RS19590	COG2197	response regulator
GN306_RS19595	COG3345	alpha-galactosidase
GN306_RS19600	COG4974	Belongs to the 'phage' integrase family
GN306_RS19650	COG0561	phosphatase activity
GN306_RS19655	COG4771	TonB-dependent receptor
GN306_RS19700	COG0702	epimerase
GN306_RS19705	COG1629	transport
GN306_RS19715	COG0745	RESPONSE REGULATOR receiver
GN306_RS19715	COG3292	Two component regulator propeller
GN306_RS19715	COG2205	protein histidine kinase activity
GN306_RS19715	COG0745	RESPONSE REGULATOR receiver
GN306_RS19715	COG3292	Two component regulator propeller
GN306_RS19715	COG2205	protein histidine kinase activity
GN306_RS19720	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS19725	COG0457	Tetratricopeptide repeat
GN306_RS19730	COG2814	Major facilitator Superfamily
GN306_RS19740	COG3537	Alpha-1,2-mannosidase
GN306_RS19745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GN306_RS19745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GN306_RS19775	COG4206	TonB-dependent receptor
GN306_RS19775	COG1629	transport
GN306_RS19790	COG2873	o-acetylhomoserine
GN306_RS19805	COG1595	DNA-templated transcription, initiation
GN306_RS19840	COG0203	ribosomal protein L17
GN306_RS19845	COG0202	RNA polymerase activity
GN306_RS19850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GN306_RS19855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GN306_RS19860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GN306_RS19865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GN306_RS19870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GN306_RS19885	COG0200	Binds to the 23S rRNA
GN306_RS19890	COG1841	ribosomal large subunit assembly
GN306_RS19895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GN306_RS19900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GN306_RS19905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GN306_RS19910	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GN306_RS19915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GN306_RS19920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GN306_RS19925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GN306_RS19930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GN306_RS19935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GN306_RS19940	COG0255	Belongs to the universal ribosomal protein uL29 family
GN306_RS19945	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GN306_RS19950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GN306_RS19955	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GN306_RS19960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GN306_RS19965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GN306_RS19970	COG0089	rRNA binding
GN306_RS19975	COG0088	Forms part of the polypeptide exit tunnel
GN306_RS19980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GN306_RS19985	COG0051	transcription antitermination factor activity, RNA binding
GN306_RS19990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GN306_RS19995	COG0049	tRNA binding
GN306_RS20000	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GN306_RS20010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GN306_RS20015	COG0085	RNA polymerase activity
GN306_RS20020	COG0222	ribosome binding
GN306_RS20025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GN306_RS20030	COG0081	regulation of translation
GN306_RS20035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GN306_RS20055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GN306_RS20085	COG4974	Belongs to the 'phage' integrase family
GN306_RS20090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GN306_RS20100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GN306_RS20115	COG0745	RESPONSE REGULATOR receiver
GN306_RS20120	COG5002	protein histidine kinase activity
GN306_RS20130	COG0793	Belongs to the peptidase S41A family
GN306_RS20135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GN306_RS20170	COG0702	epimerase
GN306_RS20175	COG0584	glycerophosphoryl diester phosphodiesterase
GN306_RS20180	COG3537	Alpha-1,2-mannosidase
GN306_RS20200	COG2205	protein histidine kinase activity
GN306_RS20200	COG0745	RESPONSE REGULATOR receiver
GN306_RS20200	COG3292	Two component regulator propeller
GN306_RS20205	COG1629	transport
GN306_RS20205	COG4206	TonB-dependent receptor
GN306_RS20210	COG0702	epimerase
GN306_RS20230	COG3634	alkyl hydroperoxide reductase activity
GN306_RS20240	COG0148	phosphopyruvate hydratase activity
GN306_RS20265	COG3250	beta-galactosidase activity
GN306_RS20280	COG4206	TonB-dependent receptor
GN306_RS20280	COG1629	transport
GN306_RS20285	COG3292	Two component regulator propeller
GN306_RS20285	COG2205	protein histidine kinase activity
GN306_RS20285	COG0745	RESPONSE REGULATOR receiver
GN306_RS20325	COG3250	beta-galactosidase activity
GN306_RS20330	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN306_RS20340	COG4974	Belongs to the 'phage' integrase family
GN306_RS20375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN306_RS20375	COG0551	DNA topoisomerase type I activity
GN306_RS20430	COG2205	protein histidine kinase activity
GN306_RS20430	COG0784	Response regulator, receiver
GN306_RS20430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN306_RS20430	COG2198	Histidine kinase
GN306_RS20505	COG3344	reverse transcriptase
GN306_RS20525	COG3344	reverse transcriptase
GN306_RS20590	COG0358	DNA primase activity
GN306_RS20665	COG3292	Two component regulator propeller
GN306_RS20665	COG2205	protein histidine kinase activity
GN306_RS20665	COG0745	RESPONSE REGULATOR receiver
GN306_RS20670	COG0519	Catalyzes the synthesis of GMP from XMP
GN306_RS20690	COG0667	Aldo Keto reductase
GN306_RS20695	COG0165	Argininosuccinate lyase
GN306_RS20705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GN306_RS20710	COG1040	competence protein
GN306_RS20720	COG2890	protein-(glutamine-N5) methyltransferase activity
GN306_RS20725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GN306_RS20725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GN306_RS20735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GN306_RS20755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GN306_RS20770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GN306_RS20785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GN306_RS20790	COG4974	Belongs to the 'phage' integrase family
GN306_RS20830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN306_RS20830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN306_RS20855	COG3475	LICD family
GN306_RS20870	COG0438	transferase activity, transferring glycosyl groups
GN306_RS20885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GN306_RS20890	COG1854	S-ribosylhomocysteine lyase activity
GN306_RS20895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GN306_RS20950	COG3292	Two component regulator propeller
GN306_RS20950	COG2205	protein histidine kinase activity
GN306_RS20950	COG0745	RESPONSE REGULATOR receiver
GN306_RS20965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GN306_RS20970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GN306_RS20975	COG1013	pyruvate-flavodoxin oxidoreductase activity
GN306_RS20980	COG0674	pyruvate-flavodoxin oxidoreductase activity
GN306_RS20980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GN306_RS20995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN306_RS21005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GN306_RS21010	COG0339	signal peptide processing
GN306_RS21030	COG0776	regulation of translation
GN306_RS21035	COG3250	beta-galactosidase activity
GN306_RS21045	COG0482	sulfurtransferase activity
GN306_RS21050	COG3119	arylsulfatase activity
GN306_RS21060	COG3507	Belongs to the glycosyl hydrolase 43 family
GN306_RS21065	COG2205	protein histidine kinase activity
GN306_RS21065	COG3292	Two component regulator propeller
GN306_RS21065	COG0745	RESPONSE REGULATOR receiver
GN306_RS21070	COG1082	Xylose isomerase domain protein TIM barrel
GN306_RS21075	COG1629	transport
GN306_RS21075	COG4206	TonB-dependent receptor
GN306_RS21095	COG0215	cysteine-tRNA ligase activity
GN306_RS21110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN306_RS21115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GN306_RS21150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN306_RS21180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GN306_RS21255	COG0205	6-phosphofructokinase activity
GN306_RS21260	COG3292	Two component regulator propeller
GN306_RS21260	COG0745	RESPONSE REGULATOR receiver
GN306_RS21260	COG2205	protein histidine kinase activity
GN306_RS21265	COG4206	TonB-dependent receptor
GN306_RS21265	COG1629	transport
GN306_RS21280	COG3119	arylsulfatase activity
GN306_RS21295	COG3119	arylsulfatase activity
GN306_RS21300	COG0571	ribonuclease III activity
GN306_RS21305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN306_RS21310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GN306_RS21315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GN306_RS21325	COG4206	TonB-dependent receptor
GN306_RS21325	COG1629	transport
GN306_RS21400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GN306_RS21415	COG0562	UDP-galactopyranose mutase
GN306_RS21445	COG0438	transferase activity, transferring glycosyl groups
GN306_RS21455	COG1132	(ABC) transporter
GN306_RS21465	COG1215	transferase activity, transferring glycosyl groups
GN306_RS21475	COG0463	Glycosyl transferase, family 2
GN306_RS21485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GN306_RS21495	COG3341	Caulimovirus viroplasmin
GN306_RS21495	COG0328	RNA-DNA hybrid ribonuclease activity
GN306_RS21500	COG0018	arginyl-trna synthetase
GN306_RS21505	COG1629	transport
GN306_RS21515	COG0826	peptidase U32
GN306_RS21520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GN306_RS21540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GN306_RS21545	COG0557	exoribonuclease II activity
GN306_RS21550	COG1045	serine acetyltransferase
GN306_RS21555	COG4251	negative regulation of phosphorylation
GN306_RS21565	COG0783	Belongs to the Dps family
GN306_RS21570	COG0583	DNA-binding transcription factor activity
GN306_RS21580	COG0116	Belongs to the methyltransferase superfamily
GN306_RS21585	COG1506	peptidase
GN306_RS21585	COG0823	Involved in the tonB-independent uptake of proteins
GN306_RS21635	COG0726	polysaccharide deacetylase
GN306_RS21650	COG0561	phosphatase activity
GN306_RS21655	COG4771	TonB-dependent receptor
GN306_RS21660	COG4677	pectinesterase activity
GN306_RS21665	COG1028	Short-chain dehydrogenase reductase Sdr
GN306_RS21670	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GN306_RS21675	COG2027	D-alanyl-D-alanine carboxypeptidase
GN306_RS21700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GN306_RS21720	COG0702	epimerase
GN306_RS21725	COG4206	TonB-dependent receptor
GN306_RS21725	COG1629	transport
GN306_RS21745	COG4948	Mandelate Racemase Muconate Lactonizing
GN306_RS21755	COG0702	epimerase
GN306_RS21760	COG1629	transport
GN306_RS21760	COG4206	TonB-dependent receptor
GN306_RS21790	COG1629	transport
GN306_RS21805	COG2205	protein histidine kinase activity
GN306_RS21805	COG0745	RESPONSE REGULATOR receiver
GN306_RS21805	COG3292	Two component regulator propeller
GN306_RS21810	COG1592	Rubrerythrin
GN306_RS21820	COG0659	secondary active sulfate transmembrane transporter activity
GN306_RS21835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN306_RS21840	COG0582	viral genome integration into host DNA
GN306_RS21900	COG5002	protein histidine kinase activity
GN306_RS21910	COG0731	radical SAM domain protein
GN306_RS21910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN306_RS21935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GN306_RS21945	COG2205	protein histidine kinase activity
GN306_RS21945	COG0745	RESPONSE REGULATOR receiver
GN306_RS21945	COG3292	Two component regulator propeller
GN306_RS21955	COG1629	transport
GN306_RS21965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GN306_RS21975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GN306_RS21980	COG0495	leucyl-tRNA aminoacylation
GN306_RS21985	COG2205	protein histidine kinase activity
GN306_RS21985	COG3292	Two component regulator propeller
GN306_RS21985	COG2205	protein histidine kinase activity
GN306_RS21985	COG0745	RESPONSE REGULATOR receiver
GN306_RS21985	COG3292	Two component regulator propeller
GN306_RS21985	COG0745	RESPONSE REGULATOR receiver
GN306_RS21990	COG3250	beta-galactosidase activity
GN306_RS21995	COG1629	transport
GN306_RS22000	COG0702	epimerase
GN306_RS22005	COG0793	Belongs to the peptidase S41A family
GN306_RS22005	COG4946	Tricorn protease homolog
GN306_RS22010	COG1595	DNA-templated transcription, initiation
GN306_RS22020	COG4206	TonB-dependent receptor
GN306_RS22020	COG1629	transport
GN306_RS22030	COG3119	arylsulfatase activity
GN306_RS22035	COG3119	arylsulfatase activity
GN306_RS22045	COG1472	Belongs to the glycosyl hydrolase 3 family
GN306_RS22050	COG0427	acetyl-CoA hydrolase
GN306_RS22060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN306_RS22065	COG0545	Peptidyl-prolyl cis-trans isomerase
GN306_RS22070	COG1983	PspC domain protein
GN306_RS22080	COG2177	Part of the ABC transporter FtsEX involved in
GN306_RS22090	COG1968	undecaprenyl-diphosphatase activity
GN306_RS22095	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GN306_RS22100	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GN306_RS22105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GN306_RS22150	COG2814	Major facilitator Superfamily
GN306_RS22155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GN306_RS22160	COG1611	Belongs to the LOG family
GN306_RS22175	COG0594	ribonuclease P activity
GN306_RS22180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GN306_RS22190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GN306_RS22240	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GN306_RS22285	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GN306_RS22295	COG0012	GTP binding
GN306_RS22305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GN306_RS22305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GN306_RS22310	COG0142	geranyltranstransferase activity
GN306_RS22320	COG1694	Mazg nucleotide pyrophosphohydrolase
GN306_RS22325	COG1490	D-aminoacyl-tRNA deacylase activity
GN306_RS22330	COG0322	excinuclease ABC activity
GN306_RS22335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis