locus-tag	class	description
GN309_RS00005	COG0445	tRNA wobble uridine modification
GN309_RS00010	COG2268	Band 7 protein
GN309_RS00020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GN309_RS00040	COG0745	RESPONSE REGULATOR receiver
GN309_RS00045	COG5002	protein histidine kinase activity
GN309_RS00050	COG0700	Nucleoside recognition
GN309_RS00115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GN309_RS00120	COG3409	Peptidoglycan-binding domain 1 protein
GN309_RS00120	COG0793	Belongs to the peptidase S41A family
GN309_RS00135	COG1053	succinate dehydrogenase
GN309_RS00200	COG0758	DNA mediated transformation
GN309_RS00200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GN309_RS00220	COG1454	alcohol dehydrogenase
GN309_RS00230	COG0584	glycerophosphoryl diester phosphodiesterase
GN309_RS00245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GN309_RS00250	COG0681	Belongs to the peptidase S26 family
GN309_RS00255	COG0681	Belongs to the peptidase S26 family
GN309_RS00265	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS00270	COG1312	Catalyzes the dehydration of D-mannonate
GN309_RS00275	COG4771	TonB-dependent receptor
GN309_RS00285	COG3119	arylsulfatase activity
GN309_RS00290	COG2205	protein histidine kinase activity
GN309_RS00290	COG2198	Histidine kinase
GN309_RS00290	COG0784	Response regulator, receiver
GN309_RS00290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN309_RS00300	COG0612	Peptidase, M16
GN309_RS00310	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GN309_RS00310	COG0517	IMP dehydrogenase activity
GN309_RS00325	COG0308	aminopeptidase N
GN309_RS00330	COG0482	sulfurtransferase activity
GN309_RS00460	COG4974	Belongs to the 'phage' integrase family
GN309_RS00465	COG2255	four-way junction helicase activity
GN309_RS00480	COG3591	Belongs to the peptidase S1B family
GN309_RS00505	COG3655	Transcriptional regulator
GN309_RS00540	COG0196	riboflavin kinase activity
GN309_RS00545	COG1011	Hydrolase
GN309_RS00550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GN309_RS00595	COG0732	type I restriction modification DNA specificity domain
GN309_RS00600	COG4974	Belongs to the 'phage' integrase family
GN309_RS00700	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GN309_RS00725	COG2166	iron-sulfur cluster assembly
GN309_RS00735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GN309_RS00740	COG0280	phosphate acetyltransferase
GN309_RS00745	COG3426	butyrate kinase activity
GN309_RS00770	COG1522	sequence-specific DNA binding
GN309_RS00780	COG1253	flavin adenine dinucleotide binding
GN309_RS00805	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GN309_RS00810	COG1166	arginine decarboxylase activity
GN309_RS00815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GN309_RS00820	COG1595	DNA-templated transcription, initiation
GN309_RS00840	COG3458	cephalosporin-C deacetylase activity
GN309_RS00885	COG2814	Major facilitator Superfamily
GN309_RS00895	COG0779	Required for maturation of 30S ribosomal subunits
GN309_RS00900	COG0195	Participates in both transcription termination and antitermination
GN309_RS00905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GN309_RS00915	COG0719	Fe-S assembly protein
GN309_RS00920	COG0396	ATPase activity
GN309_RS00925	COG0719	Fe-S assembly protein
GN309_RS00930	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GN309_RS00935	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GN309_RS00935	COG3408	Glycogen debranching enzyme
GN309_RS00940	COG3250	beta-galactosidase activity
GN309_RS00945	COG2431	L-lysine efflux transmembrane transporter activity
GN309_RS00955	COG0702	epimerase
GN309_RS00960	COG4206	TonB-dependent receptor
GN309_RS00960	COG1629	transport
GN309_RS00970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GN309_RS00975	COG0738	Major facilitator superfamily
GN309_RS00980	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
GN309_RS00990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GN309_RS01020	COG0366	Alpha amylase catalytic
GN309_RS01035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS01040	COG4206	TonB-dependent receptor
GN309_RS01040	COG1629	transport
GN309_RS01050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS01060	COG1082	Xylose isomerase domain protein TIM barrel
GN309_RS01065	COG0366	Alpha amylase catalytic
GN309_RS01085	COG3385	transposase activity
GN309_RS01110	COG1640	4-alpha-glucanotransferase
GN309_RS01115	COG0187	DNA topoisomerase II activity
GN309_RS01120	COG0268	Binds directly to 16S ribosomal RNA
GN309_RS01130	COG1381	Involved in DNA repair and RecF pathway recombination
GN309_RS01140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GN309_RS01155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GN309_RS01160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GN309_RS01165	COG0772	Belongs to the SEDS family
GN309_RS01170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GN309_RS01175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GN309_RS01180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GN309_RS01185	COG0768	penicillin binding
GN309_RS01195	COG0275	rRNA processing
GN309_RS01200	COG2001	Belongs to the MraZ family
GN309_RS01220	COG0756	dUTP diphosphatase activity
GN309_RS01225	COG3063	Type IV pilus biogenesis stability protein PilW
GN309_RS01245	COG0724	RNA recognition motif
GN309_RS01250	COG2066	Belongs to the glutaminase family
GN309_RS01255	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GN309_RS01260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GN309_RS01265	COG0509	glycine decarboxylation via glycine cleavage system
GN309_RS01280	COG0006	proline dipeptidase activity
GN309_RS01300	COG0572	uridine kinase
GN309_RS01305	COG1283	sodium-dependent phosphate transmembrane transporter activity
GN309_RS01310	COG1283	sodium-dependent phosphate transmembrane transporter activity
GN309_RS01320	COG0545	Peptidyl-prolyl cis-trans isomerase
GN309_RS01325	COG0545	Peptidyl-prolyl cis-trans isomerase
GN309_RS01330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GN309_RS01335	COG1773	rubredoxin
GN309_RS01340	COG1185	polyribonucleotide nucleotidyltransferase activity
GN309_RS01350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GN309_RS01385	COG0519	Catalyzes the synthesis of GMP from XMP
GN309_RS01390	COG3292	Two component regulator propeller
GN309_RS01390	COG2205	protein histidine kinase activity
GN309_RS01390	COG0745	RESPONSE REGULATOR receiver
GN309_RS01395	COG4771	TonB-dependent receptor
GN309_RS01400	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS01405	COG3250	beta-galactosidase activity
GN309_RS01445	COG0745	RESPONSE REGULATOR receiver
GN309_RS01445	COG3292	Two component regulator propeller
GN309_RS01445	COG2205	protein histidine kinase activity
GN309_RS01450	COG1629	transport
GN309_RS01450	COG4206	TonB-dependent receptor
GN309_RS01465	COG3250	beta-galactosidase activity
GN309_RS01490	COG0148	phosphopyruvate hydratase activity
GN309_RS01500	COG3634	alkyl hydroperoxide reductase activity
GN309_RS01505	COG1609	Transcriptional regulator
GN309_RS01520	COG0702	epimerase
GN309_RS01525	COG1629	transport
GN309_RS01525	COG4206	TonB-dependent receptor
GN309_RS01530	COG0745	RESPONSE REGULATOR receiver
GN309_RS01530	COG3292	Two component regulator propeller
GN309_RS01530	COG2205	protein histidine kinase activity
GN309_RS01550	COG3537	Alpha-1,2-mannosidase
GN309_RS01555	COG0584	glycerophosphoryl diester phosphodiesterase
GN309_RS01560	COG0702	epimerase
GN309_RS01565	COG1629	transport
GN309_RS01565	COG4206	TonB-dependent receptor
GN309_RS01595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GN309_RS01600	COG0793	Belongs to the peptidase S41A family
GN309_RS01610	COG5002	protein histidine kinase activity
GN309_RS01615	COG0745	RESPONSE REGULATOR receiver
GN309_RS01630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GN309_RS01640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GN309_RS01645	COG4974	Belongs to the 'phage' integrase family
GN309_RS01675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GN309_RS01695	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GN309_RS01700	COG0081	regulation of translation
GN309_RS01705	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GN309_RS01710	COG0222	ribosome binding
GN309_RS01715	COG0085	RNA polymerase activity
GN309_RS01720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GN309_RS01730	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GN309_RS01735	COG0049	tRNA binding
GN309_RS01740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GN309_RS01745	COG0051	transcription antitermination factor activity, RNA binding
GN309_RS01750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GN309_RS01755	COG0088	Forms part of the polypeptide exit tunnel
GN309_RS01760	COG0089	rRNA binding
GN309_RS01765	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GN309_RS01770	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GN309_RS01775	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GN309_RS01780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GN309_RS01785	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GN309_RS01790	COG0255	Belongs to the universal ribosomal protein uL29 family
GN309_RS01795	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GN309_RS01800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GN309_RS01805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GN309_RS01810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GN309_RS01815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GN309_RS01820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GN309_RS01825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GN309_RS01830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GN309_RS01835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GN309_RS01840	COG1841	ribosomal large subunit assembly
GN309_RS01845	COG0200	Binds to the 23S rRNA
GN309_RS01860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GN309_RS01865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GN309_RS01870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GN309_RS01875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GN309_RS01880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GN309_RS01885	COG0202	RNA polymerase activity
GN309_RS01890	COG0203	ribosomal protein L17
GN309_RS01925	COG1595	DNA-templated transcription, initiation
GN309_RS01940	COG2873	o-acetylhomoserine
GN309_RS01990	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GN309_RS01990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GN309_RS01995	COG3537	Alpha-1,2-mannosidase
GN309_RS02005	COG2814	Major facilitator Superfamily
GN309_RS02010	COG0457	Tetratricopeptide repeat
GN309_RS02015	COG4948	Mandelate Racemase Muconate Lactonizing
GN309_RS02020	COG3292	Two component regulator propeller
GN309_RS02020	COG0745	RESPONSE REGULATOR receiver
GN309_RS02020	COG3292	Two component regulator propeller
GN309_RS02020	COG2205	protein histidine kinase activity
GN309_RS02020	COG0745	RESPONSE REGULATOR receiver
GN309_RS02020	COG2205	protein histidine kinase activity
GN309_RS02030	COG1629	transport
GN309_RS02035	COG0702	epimerase
GN309_RS02080	COG4771	TonB-dependent receptor
GN309_RS02085	COG0561	phosphatase activity
GN309_RS02135	COG4974	Belongs to the 'phage' integrase family
GN309_RS02140	COG3345	alpha-galactosidase
GN309_RS02145	COG2197	response regulator
GN309_RS02165	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GN309_RS02170	COG0542	response to heat
GN309_RS02175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GN309_RS02205	COG3537	Alpha-1,2-mannosidase
GN309_RS02210	COG4771	TonB-dependent receptor
GN309_RS02230	COG1082	Xylose isomerase domain protein TIM barrel
GN309_RS02240	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GN309_RS02245	COG2249	NAD(P)H dehydrogenase (quinone) activity
GN309_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS02255	COG0656	L-ascorbic acid biosynthetic process
GN309_RS02260	COG0656	L-ascorbic acid biosynthetic process
GN309_RS02275	COG0673	inositol 2-dehydrogenase activity
GN309_RS02295	COG3250	beta-galactosidase activity
GN309_RS02300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GN309_RS02305	COG1388	LysM domain
GN309_RS02305	COG0741	lytic transglycosylase activity
GN309_RS02315	COG2205	protein histidine kinase activity
GN309_RS02315	COG0745	RESPONSE REGULATOR receiver
GN309_RS02315	COG3292	Two component regulator propeller
GN309_RS02320	COG4206	TonB-dependent receptor
GN309_RS02320	COG1629	transport
GN309_RS02325	COG0702	epimerase
GN309_RS02340	COG0235	Class ii aldolase
GN309_RS02350	COG4806	L-rhamnose isomerase
GN309_RS02355	COG1070	Carbohydrate kinase
GN309_RS02360	COG1438	arginine binding
GN309_RS02370	COG0137	argininosuccinate synthase activity
GN309_RS02375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GN309_RS02380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GN309_RS02385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GN309_RS02390	COG1368	sulfuric ester hydrolase activity
GN309_RS02395	COG0667	Aldo Keto reductase
GN309_RS02400	COG0348	domain, Protein
GN309_RS02415	COG1917	Cupin 2, conserved barrel domain protein
GN309_RS02415	COG1396	sequence-specific DNA binding
GN309_RS02420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GN309_RS02435	COG1629	transport
GN309_RS02435	COG4206	TonB-dependent receptor
GN309_RS02450	COG4206	TonB-dependent receptor
GN309_RS02450	COG1629	transport
GN309_RS02465	COG4206	TonB-dependent receptor
GN309_RS02465	COG1629	transport
GN309_RS02475	COG4206	TonB-dependent receptor
GN309_RS02475	COG1629	transport
GN309_RS02490	COG4206	TonB-dependent receptor
GN309_RS02490	COG1629	transport
GN309_RS02510	COG4771	TonB-dependent receptor
GN309_RS02520	COG1629	transport
GN309_RS02520	COG4206	TonB-dependent receptor
GN309_RS02545	COG0561	phosphatase activity
GN309_RS02550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GN309_RS02555	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GN309_RS02560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GN309_RS02580	COG1181	Belongs to the D-alanine--D-alanine ligase family
GN309_RS02585	COG0564	pseudouridine synthase activity
GN309_RS02605	COG0745	RESPONSE REGULATOR receiver
GN309_RS02605	COG3292	Two component regulator propeller
GN309_RS02605	COG2205	protein histidine kinase activity
GN309_RS02610	COG0657	acetylesterase activity
GN309_RS02610	COG2755	lipolytic protein G-D-S-L family
GN309_RS02615	COG4771	TonB-dependent receptor
GN309_RS02620	COG0702	epimerase
GN309_RS02625	COG3119	arylsulfatase activity
GN309_RS02630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS02660	COG0641	radical SAM
GN309_RS02665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GN309_RS02670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GN309_RS02675	COG1216	Glycosyl transferase, family 2
GN309_RS02675	COG0463	Glycosyl transferase, family 2
GN309_RS02680	COG2003	Belongs to the UPF0758 family
GN309_RS02685	COG2151	metal-sulfur cluster biosynthetic enzyme
GN309_RS02690	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN309_RS02695	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GN309_RS02700	COG0280	phosphate acetyltransferase
GN309_RS02710	COG1346	cytolysis
GN309_RS02725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GN309_RS02730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GN309_RS02735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GN309_RS02755	COG3292	Two component regulator propeller
GN309_RS02755	COG2205	protein histidine kinase activity
GN309_RS02755	COG0745	RESPONSE REGULATOR receiver
GN309_RS02760	COG4206	TonB-dependent receptor
GN309_RS02760	COG1629	transport
GN309_RS02770	COG4771	TonB-dependent receptor
GN309_RS02780	COG3507	Belongs to the glycosyl hydrolase 43 family
GN309_RS02795	COG0702	epimerase
GN309_RS02800	COG4771	TonB-dependent receptor
GN309_RS02805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GN309_RS02820	COG4771	TonB-dependent receptor
GN309_RS02825	COG0702	epimerase
GN309_RS02830	COG3408	Glycogen debranching enzyme
GN309_RS02850	COG4977	sequence-specific DNA binding
GN309_RS02855	COG4206	TonB-dependent receptor
GN309_RS02855	COG1629	transport
GN309_RS02860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS02870	COG0420	3'-5' exonuclease activity
GN309_RS02915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GN309_RS02920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GN309_RS02925	COG0811	peptide transport
GN309_RS02930	COG0848	biopolymer transport protein
GN309_RS02945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GN309_RS02950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GN309_RS02955	COG0105	UTP biosynthetic process
GN309_RS02960	COG0739	heme binding
GN309_RS02975	COG0149	triose-phosphate isomerase activity
GN309_RS02985	COG0302	gtp cyclohydrolase
GN309_RS02990	COG0358	DNA primase activity
GN309_RS02995	COG0039	L-malate dehydrogenase activity
GN309_RS03050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GN309_RS03055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GN309_RS03060	COG1160	GTP binding
GN309_RS03065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GN309_RS03070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GN309_RS03080	COG0724	RNA recognition motif
GN309_RS03085	COG0544	peptidyl-prolyl cis-trans isomerase activity
GN309_RS03090	COG0740	serine-type endopeptidase activity
GN309_RS03095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GN309_RS03105	COG0516	GMP reductase activity
GN309_RS03105	COG0517	IMP dehydrogenase activity
GN309_RS03135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GN309_RS03145	COG1218	3'(2'),5'-bisphosphate nucleotidase
GN309_RS03150	COG0471	metal ion transport
GN309_RS03150	COG3273	potassium ion transport
GN309_RS03155	COG0529	Catalyzes the synthesis of activated sulfate
GN309_RS03160	COG0175	sulfate reduction
GN309_RS03165	COG2895	sulfate adenylyltransferase (ATP) activity
GN309_RS03175	COG2885	chlorophyll binding
GN309_RS03180	COG3022	response to hydroperoxide
GN309_RS03195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GN309_RS03225	COG2197	response regulator
GN309_RS03230	COG0482	sulfurtransferase activity
GN309_RS03250	COG0513	Belongs to the DEAD box helicase family
GN309_RS03255	COG1629	transport
GN309_RS03255	COG4206	TonB-dependent receptor
GN309_RS03275	COG3250	beta-galactosidase activity
GN309_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS03295	COG0564	pseudouridine synthase activity
GN309_RS03305	COG2204	response regulator
GN309_RS03310	COG2205	protein histidine kinase activity
GN309_RS03310	COG0784	Response regulator, receiver
GN309_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN309_RS03310	COG2198	Histidine kinase
GN309_RS03315	COG0534	Mate efflux family protein
GN309_RS03325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GN309_RS03400	COG1629	transport
GN309_RS03410	COG2205	protein histidine kinase activity
GN309_RS03410	COG3292	Two component regulator propeller
GN309_RS03410	COG3292	Two component regulator propeller
GN309_RS03410	COG0745	RESPONSE REGULATOR receiver
GN309_RS03410	COG0745	RESPONSE REGULATOR receiver
GN309_RS03410	COG2205	protein histidine kinase activity
GN309_RS03420	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN309_RS03420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN309_RS03425	COG1349	DNA-binding transcription factor activity
GN309_RS03430	COG3959	Transketolase, thiamine diphosphate binding domain
GN309_RS03435	COG3958	Transketolase
GN309_RS03440	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GN309_RS03455	COG1879	ABC-type sugar transport system periplasmic component
GN309_RS03460	COG0124	histidyl-tRNA synthetase
GN309_RS03465	COG1203	CRISPR-associated helicase, Cas3
GN309_RS03495	COG1518	maintenance of DNA repeat elements
GN309_RS03500	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GN309_RS03510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GN309_RS03520	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN309_RS03530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GN309_RS03535	COG0459	protein refolding
GN309_RS03555	COG0288	reversible hydration of carbon dioxide
GN309_RS03560	COG0673	inositol 2-dehydrogenase activity
GN309_RS03580	COG0693	protein deglycase activity
GN309_RS03590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GN309_RS03595	COG2986	histidine ammonia-lyase
GN309_RS03600	COG3404	Formiminotransferase-cyclodeaminase
GN309_RS03605	COG1228	amidohydrolase
GN309_RS03615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GN309_RS03630	COG4804	nuclease activity
GN309_RS03640	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GN309_RS03650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GN309_RS03670	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GN309_RS03675	COG2086	electron transfer activity
GN309_RS03690	COG0681	Belongs to the peptidase S26 family
GN309_RS03715	COG0668	transmembrane transport
GN309_RS03720	COG2205	protein histidine kinase activity
GN309_RS03735	COG1629	transport
GN309_RS03745	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN309_RS03745	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN309_RS03750	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GN309_RS03755	COG2985	domain, Protein
GN309_RS03755	COG0569	domain protein
GN309_RS03760	COG0488	(ABC) transporter
GN309_RS03775	COG4771	TonB-dependent receptor
GN309_RS03780	COG0702	epimerase
GN309_RS03785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GN309_RS03785	COG3408	Glycogen debranching enzyme
GN309_RS03790	COG3250	beta-galactosidase activity
GN309_RS03800	COG1629	transport
GN309_RS03805	COG1088	dTDP-glucose 4,6-dehydratase activity
GN309_RS03815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GN309_RS03950	COG0534	Mate efflux family protein
GN309_RS03960	COG1570	exodeoxyribonuclease VII activity
GN309_RS03965	COG1722	exodeoxyribonuclease VII activity
GN309_RS03970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GN309_RS03985	COG0489	protein tyrosine kinase activity
GN309_RS04000	COG3015	lipoprotein NlpE involved in copper resistance
GN309_RS04015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS04030	COG0039	L-malate dehydrogenase activity
GN309_RS04040	COG1475	DNA binding
GN309_RS04045	COG3969	phosphoadenosine phosphosulfate
GN309_RS04085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GN309_RS04095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS04125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS04150	COG1696	Membrane protein involved in D-alanine export
GN309_RS04185	COG2095	MarC family integral membrane protein
GN309_RS04190	COG1063	alcohol dehydrogenase
GN309_RS04195	COG0738	Major facilitator superfamily
GN309_RS04210	COG2207	Transcriptional regulator
GN309_RS04220	COG1629	transport
GN309_RS04225	COG0702	epimerase
GN309_RS04255	COG0423	glycine-tRNA ligase activity
GN309_RS04265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GN309_RS04270	COG0589	response to stress
GN309_RS04270	COG0475	glutathione-regulated potassium exporter activity
GN309_RS04275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GN309_RS04280	COG1136	(ABC) transporter
GN309_RS04290	COG1979	alcohol dehydrogenase
GN309_RS04295	COG2996	Protein conserved in bacteria
GN309_RS04315	COG1136	(ABC) transporter
GN309_RS04315	COG0577	efflux transmembrane transporter activity
GN309_RS04320	COG1136	(ABC) transporter
GN309_RS04320	COG0577	efflux transmembrane transporter activity
GN309_RS04325	COG1136	(ABC) transporter
GN309_RS04330	COG1940	carbohydrate kinase activity
GN309_RS04335	COG3254	rhamnose metabolic process
GN309_RS04375	COG2755	lipolytic protein G-D-S-L family
GN309_RS04380	COG3250	beta-galactosidase activity
GN309_RS04390	COG1874	Beta-galactosidase
GN309_RS04405	COG3401	FG-GAP repeat protein
GN309_RS04430	COG4771	TonB-dependent receptor
GN309_RS04440	COG4771	TonB-dependent receptor
GN309_RS04450	COG1629	transport
GN309_RS04450	COG4206	TonB-dependent receptor
GN309_RS04465	COG4206	TonB-dependent receptor
GN309_RS04465	COG1629	transport
GN309_RS04470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS04485	COG3119	arylsulfatase activity
GN309_RS04495	COG3250	beta-galactosidase activity
GN309_RS04500	COG3401	FG-GAP repeat protein
GN309_RS04505	COG2755	lipolytic protein G-D-S-L family
GN309_RS04525	COG4771	TonB-dependent receptor
GN309_RS04530	COG0702	epimerase
GN309_RS04560	COG3401	FG-GAP repeat protein
GN309_RS04565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS04570	COG3254	rhamnose metabolic process
GN309_RS04575	COG0745	RESPONSE REGULATOR receiver
GN309_RS04575	COG2205	protein histidine kinase activity
GN309_RS04575	COG3292	Two component regulator propeller
GN309_RS04580	COG0335	large ribosomal subunit rRNA binding
GN309_RS04585	COG0737	Belongs to the 5'-nucleotidase family
GN309_RS04590	COG0737	Belongs to the 5'-nucleotidase family
GN309_RS04595	COG1472	Belongs to the glycosyl hydrolase 3 family
GN309_RS04605	COG0436	Aminotransferase
GN309_RS04610	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN309_RS04610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GN309_RS04635	COG3292	Two component regulator propeller
GN309_RS04635	COG0745	RESPONSE REGULATOR receiver
GN309_RS04635	COG2205	protein histidine kinase activity
GN309_RS04640	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS04650	COG1082	Xylose isomerase domain protein TIM barrel
GN309_RS04660	COG1629	transport
GN309_RS04665	COG0702	epimerase
GN309_RS04675	COG4948	Mandelate Racemase Muconate Lactonizing
GN309_RS04685	COG1472	Belongs to the glycosyl hydrolase 3 family
GN309_RS04700	COG3250	beta-galactosidase activity
GN309_RS04715	COG1595	DNA-templated transcription, initiation
GN309_RS04720	COG1629	transport
GN309_RS04720	COG4206	TonB-dependent receptor
GN309_RS04770	COG3940	Belongs to the glycosyl hydrolase 43 family
GN309_RS04780	COG2267	carboxylic ester hydrolase activity
GN309_RS04805	COG4948	Mandelate Racemase Muconate Lactonizing
GN309_RS04815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS04825	COG4206	TonB-dependent receptor
GN309_RS04825	COG1629	transport
GN309_RS04835	COG0386	Belongs to the glutathione peroxidase family
GN309_RS04855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GN309_RS04865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN309_RS04870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GN309_RS04870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GN309_RS04875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN309_RS04880	COG1078	dGTPase activity
GN309_RS04885	COG0284	orotidine-5'-phosphate decarboxylase activity
GN309_RS04890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GN309_RS04895	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GN309_RS04905	COG1966	Carbon starvation protein
GN309_RS04920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS04935	COG1649	PFAM Uncharacterised BCR, COG1649
GN309_RS04940	COG1501	Belongs to the glycosyl hydrolase 31 family
GN309_RS04955	COG2059	Chromate
GN309_RS04960	COG2205	protein histidine kinase activity
GN309_RS04960	COG0745	RESPONSE REGULATOR receiver
GN309_RS04960	COG3292	Two component regulator propeller
GN309_RS04965	COG0047	phosphoribosylformylglycinamidine synthase activity
GN309_RS04965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GN309_RS04970	COG1280	lysine exporter protein (LysE YggA)
GN309_RS04985	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GN309_RS05005	COG0745	RESPONSE REGULATOR receiver
GN309_RS05005	COG3292	Two component regulator propeller
GN309_RS05005	COG2205	protein histidine kinase activity
GN309_RS05070	COG0681	Belongs to the peptidase S26 family
GN309_RS05105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GN309_RS05110	COG2205	protein histidine kinase activity
GN309_RS05110	COG0745	RESPONSE REGULATOR receiver
GN309_RS05110	COG2205	protein histidine kinase activity
GN309_RS05110	COG3292	Two component regulator propeller
GN309_RS05110	COG0745	RESPONSE REGULATOR receiver
GN309_RS05110	COG3292	Two component regulator propeller
GN309_RS05120	COG4771	TonB-dependent receptor
GN309_RS05135	COG0009	L-threonylcarbamoyladenylate synthase
GN309_RS05145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GN309_RS05165	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GN309_RS05170	COG2333	competence protein COMEC
GN309_RS05170	COG0658	competence protein
GN309_RS05175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GN309_RS05185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GN309_RS05195	COG2211	Major facilitator Superfamily
GN309_RS05210	COG3507	Belongs to the glycosyl hydrolase 43 family
GN309_RS05215	COG4206	TonB-dependent receptor
GN309_RS05215	COG1629	transport
GN309_RS05225	COG0745	RESPONSE REGULATOR receiver
GN309_RS05225	COG2205	protein histidine kinase activity
GN309_RS05225	COG3292	Two component regulator propeller
GN309_RS05230	COG3507	Belongs to the glycosyl hydrolase 43 family
GN309_RS05240	COG3661	Belongs to the glycosyl hydrolase 67 family
GN309_RS05290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GN309_RS05295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GN309_RS05320	COG0360	Binds together with S18 to 16S ribosomal RNA
GN309_RS05325	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GN309_RS05330	COG0359	binds to the 23S rRNA
GN309_RS05340	COG0318	PFAM AMP-dependent synthetase and ligase
GN309_RS05345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN309_RS05360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GN309_RS05375	COG0778	Nitroreductase
GN309_RS05380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GN309_RS05390	COG0860	N-Acetylmuramoyl-L-alanine amidase
GN309_RS05440	COG3385	transposase activity
GN309_RS05470	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GN309_RS05475	COG4804	nuclease activity
GN309_RS05480	COG0732	type I restriction modification DNA specificity domain
GN309_RS05490	COG0732	type I restriction modification DNA specificity domain
GN309_RS05545	COG3876	Protein conserved in bacteria
GN309_RS05560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GN309_RS05565	COG2502	aspartate--ammonia ligase
GN309_RS05575	COG4206	TonB-dependent receptor
GN309_RS05575	COG1629	transport
GN309_RS05590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS05610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS05620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS05630	COG3250	beta-galactosidase activity
GN309_RS05640	COG0745	RESPONSE REGULATOR receiver
GN309_RS05705	COG4977	sequence-specific DNA binding
GN309_RS05705	COG1917	Cupin 2, conserved barrel domain protein
GN309_RS05715	COG0363	glucosamine-6-phosphate deaminase activity
GN309_RS05720	COG0363	glucosamine-6-phosphate deaminase activity
GN309_RS05725	COG2271	Major facilitator Superfamily
GN309_RS05740	COG1940	carbohydrate kinase activity
GN309_RS05755	COG4771	TonB-dependent receptor
GN309_RS05760	COG0702	epimerase
GN309_RS05770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GN309_RS05775	COG0166	Belongs to the GPI family
GN309_RS05780	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GN309_RS05785	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GN309_RS05795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS05805	COG1530	ribonuclease E activity
GN309_RS05810	COG0776	regulation of translation
GN309_RS05820	COG0629	single-stranded DNA binding
GN309_RS05835	COG5002	protein histidine kinase activity
GN309_RS05840	COG0745	RESPONSE REGULATOR receiver
GN309_RS05845	COG0252	asparaginase activity
GN309_RS05850	COG0159	tryptophan synthase activity
GN309_RS05855	COG0135	phosphoribosylanthranilate isomerase activity
GN309_RS05860	COG0134	indole-3-glycerol-phosphate synthase activity
GN309_RS05865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GN309_RS05870	COG0512	Glutamine amidotransferase of anthranilate synthase
GN309_RS05875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GN309_RS05880	COG0133	tryptophan synthase activity
GN309_RS05910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS05935	COG0477	Major facilitator Superfamily
GN309_RS05935	COG2814	Major facilitator Superfamily
GN309_RS05940	COG4946	Tricorn protease homolog
GN309_RS05940	COG1506	peptidase
GN309_RS05940	COG0823	Involved in the tonB-independent uptake of proteins
GN309_RS05985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GN309_RS05990	COG0242	peptide deformylase activity
GN309_RS06000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GN309_RS06005	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GN309_RS06010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GN309_RS06015	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GN309_RS06025	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GN309_RS06090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GN309_RS06095	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS06110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GN309_RS06115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GN309_RS06130	COG2089	acid synthase
GN309_RS06135	COG1083	cytidylyl-transferase
GN309_RS06140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN309_RS06175	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GN309_RS06210	COG1216	Glycosyl transferase, family 2
GN309_RS06215	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GN309_RS06260	COG1895	HEPN domain
GN309_RS06355	COG3646	Phage regulatory protein
GN309_RS06370	COG4974	Belongs to the 'phage' integrase family
GN309_RS06830	COG2197	response regulator
GN309_RS06865	COG0367	asparagine synthase
GN309_RS06875	COG0067	glutamate synthase
GN309_RS06875	COG0069	glutamate synthase activity
GN309_RS06875	COG0070	glutamate synthase
GN309_RS06880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GN309_RS06890	COG0505	Belongs to the CarA family
GN309_RS06905	COG0071	Belongs to the small heat shock protein (HSP20) family
GN309_RS06910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GN309_RS06925	COG0366	Alpha amylase catalytic
GN309_RS06935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GN309_RS06940	COG0351	phosphomethylpyrimidine kinase
GN309_RS06940	COG0352	thiamine-phosphate diphosphorylase activity
GN309_RS06945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS06960	COG2205	protein histidine kinase activity
GN309_RS06960	COG0784	Response regulator, receiver
GN309_RS06965	COG0745	RESPONSE REGULATOR receiver
GN309_RS06970	COG0463	Glycosyl transferase, family 2
GN309_RS06980	COG1442	glycosyl transferase family 8
GN309_RS06980	COG1216	Glycosyl transferase, family 2
GN309_RS06990	COG0438	transferase activity, transferring glycosyl groups
GN309_RS07010	COG1215	transferase activity, transferring glycosyl groups
GN309_RS07020	COG0438	transferase activity, transferring glycosyl groups
GN309_RS07040	COG1216	Glycosyl transferase, family 2
GN309_RS07045	COG1216	Glycosyl transferase, family 2
GN309_RS07070	COG1215	transferase activity, transferring glycosyl groups
GN309_RS07090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN309_RS07095	COG0745	RESPONSE REGULATOR receiver
GN309_RS07095	COG2205	protein histidine kinase activity
GN309_RS07095	COG3292	Two component regulator propeller
GN309_RS07110	COG2115	Belongs to the xylose isomerase family
GN309_RS07135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN309_RS07145	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GN309_RS07150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS07155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GN309_RS07170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GN309_RS07175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GN309_RS07180	COG0573	inorganic phosphate transmembrane transporter activity
GN309_RS07185	COG0581	inorganic phosphate transmembrane transporter activity
GN309_RS07190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GN309_RS07255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GN309_RS07415	COG0740	serine-type endopeptidase activity
GN309_RS07500	COG3392	D12 class N6 adenine-specific DNA methyltransferase
GN309_RS07510	COG3475	LICD family
GN309_RS07525	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GN309_RS07585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GN309_RS07590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GN309_RS07610	COG0481	GTPase activity
GN309_RS07615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GN309_RS07620	COG5002	protein histidine kinase activity
GN309_RS07625	COG0531	amino acid
GN309_RS07645	COG3142	Participates in the control of copper homeostasis
GN309_RS07650	COG2066	Belongs to the glutaminase family
GN309_RS07655	COG0076	glutamate decarboxylase activity
GN309_RS07665	COG0697	spore germination
GN309_RS07670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GN309_RS07685	COG4656	Part of a membrane complex involved in electron transport
GN309_RS07690	COG4658	electron transport chain
GN309_RS07695	COG4659	FMN binding
GN309_RS07700	COG4660	Part of a membrane complex involved in electron transport
GN309_RS07705	COG4657	Part of a membrane complex involved in electron transport
GN309_RS07715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GN309_RS07725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GN309_RS07730	COG1027	Aspartate ammonia-lyase
GN309_RS07780	COG0167	dihydroorotate dehydrogenase activity
GN309_RS07785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GN309_RS07800	COG0436	Aminotransferase
GN309_RS07810	COG2431	L-lysine efflux transmembrane transporter activity
GN309_RS07835	COG0019	diaminopimelate decarboxylase activity
GN309_RS07840	COG0527	aspartate kinase activity
GN309_RS07845	COG2884	Cell division ATP-binding protein ftsE
GN309_RS07850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GN309_RS07850	COG0140	phosphoribosyl-ATP diphosphatase activity
GN309_RS07855	COG0107	imidazoleglycerol-phosphate synthase activity
GN309_RS07860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GN309_RS07870	COG0788	formyltetrahydrofolate deformylase activity
GN309_RS07890	COG4974	Belongs to the 'phage' integrase family
GN309_RS07910	COG4974	Belongs to the 'phage' integrase family
GN309_RS08040	COG3385	transposase activity
GN309_RS08120	COG0745	RESPONSE REGULATOR receiver
GN309_RS08125	COG5002	protein histidine kinase activity
GN309_RS08125	COG3850	Histidine kinase
GN309_RS08130	COG0671	phosphoesterase, PA-phosphatase related
GN309_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS08145	COG4977	sequence-specific DNA binding
GN309_RS08145	COG1917	Cupin 2, conserved barrel domain protein
GN309_RS08150	COG3708	Transcriptional regulator
GN309_RS08150	COG2207	Transcriptional regulator
GN309_RS08205	COG0667	Aldo Keto reductase
GN309_RS08215	COG0656	L-ascorbic acid biosynthetic process
GN309_RS08240	COG0534	Mate efflux family protein
GN309_RS08245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GN309_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS08275	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS08280	COG0667	Aldo Keto reductase
GN309_RS08295	COG0697	spore germination
GN309_RS08300	COG2311	Membrane
GN309_RS08305	COG0667	Aldo Keto reductase
GN309_RS08330	COG0655	NAD(P)H dehydrogenase (quinone) activity
GN309_RS08345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GN309_RS08350	COG0805	protein transport
GN309_RS08410	COG3250	beta-galactosidase activity
GN309_RS08415	COG0656	L-ascorbic acid biosynthetic process
GN309_RS08420	COG0656	L-ascorbic acid biosynthetic process
GN309_RS08500	COG5146	pantothenate kinase activity
GN309_RS08515	COG2205	protein histidine kinase activity
GN309_RS08515	COG3292	Two component regulator propeller
GN309_RS08515	COG0745	RESPONSE REGULATOR receiver
GN309_RS08525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GN309_RS08530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GN309_RS08535	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN309_RS08540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GN309_RS08545	COG4651	solute:proton antiporter activity
GN309_RS08545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GN309_RS08555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GN309_RS08560	COG0193	aminoacyl-tRNA hydrolase activity
GN309_RS08565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GN309_RS08575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GN309_RS08580	COG1862	Preprotein translocase
GN309_RS08600	COG0542	response to heat
GN309_RS08610	COG0583	DNA-binding transcription factor activity
GN309_RS08615	COG2855	membrane
GN309_RS08635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GN309_RS08640	COG0805	protein transport
GN309_RS08645	COG0686	Belongs to the AlaDH PNT family
GN309_RS08650	COG0739	heme binding
GN309_RS08660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GN309_RS08675	COG3275	phosphorelay sensor kinase activity
GN309_RS08680	COG3279	Response regulator of the LytR AlgR family
GN309_RS08760	COG1538	Outer membrane efflux protein
GN309_RS08780	COG0534	Mate efflux family protein
GN309_RS08785	COG0564	pseudouridine synthase activity
GN309_RS08810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GN309_RS08825	COG0346	lactoylglutathione lyase activity
GN309_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS08845	COG1063	alcohol dehydrogenase
GN309_RS08905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GN309_RS08915	COG0813	purine-nucleoside phosphorylase activity
GN309_RS08920	COG4864	UPF0365 protein
GN309_RS08935	COG0037	tRNA processing
GN309_RS08955	COG0543	2 iron, 2 sulfur cluster binding
GN309_RS08965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GN309_RS08980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GN309_RS08985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GN309_RS08990	COG0546	phosphoglycolate phosphatase activity
GN309_RS08995	COG0791	NLP P60 protein
GN309_RS09000	COG1131	(ABC) transporter
GN309_RS09010	COG0612	Peptidase, M16
GN309_RS09015	COG0492	ferredoxin-NADP+ reductase activity
GN309_RS09025	COG1674	ftsk spoiiie
GN309_RS09040	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GN309_RS09045	COG1408	metallophosphoesterase
GN309_RS09095	COG2211	Major facilitator Superfamily
GN309_RS09115	COG4133	protoheme IX ABC transporter activity
GN309_RS09135	COG1012	belongs to the aldehyde dehydrogenase family
GN309_RS09140	COG1595	DNA-templated transcription, initiation
GN309_RS09160	COG4206	TonB-dependent receptor
GN309_RS09160	COG1629	transport
GN309_RS09195	COG3119	arylsulfatase activity
GN309_RS09210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS09240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS09255	COG0519	Catalyzes the synthesis of GMP from XMP
GN309_RS09260	COG0519	Catalyzes the synthesis of GMP from XMP
GN309_RS09260	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GN309_RS09265	COG1970	mechanosensitive ion channel activity
GN309_RS09275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GN309_RS09280	COG1597	lipid kinase activity
GN309_RS09285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GN309_RS09320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS09370	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GN309_RS09385	COG1269	ATP hydrolysis coupled proton transport
GN309_RS09390	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN309_RS09400	COG0058	SHG alpha-glucan phosphorylase activity
GN309_RS09405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS09435	COG1177	transmembrane transport
GN309_RS09445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GN309_RS09450	COG0352	thiamine-phosphate diphosphorylase activity
GN309_RS09460	COG0754	glutathionylspermidine amidase activity
GN309_RS09465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GN309_RS09485	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GN309_RS09490	COG2022	thiamine diphosphate biosynthetic process
GN309_RS09495	COG0352	thiamine-phosphate diphosphorylase activity
GN309_RS09555	COG3153	acetyltransferase
GN309_RS09555	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GN309_RS09560	COG3852	Histidine kinase
GN309_RS09580	COG4974	Belongs to the 'phage' integrase family
GN309_RS09615	COG4206	TonB-dependent receptor
GN309_RS09615	COG1629	transport
GN309_RS09710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GN309_RS09720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GN309_RS09735	COG1678	Uncharacterized ACR, COG1678
GN309_RS09765	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GN309_RS09770	COG1151	hydroxylamine reductase activity
GN309_RS09780	COG3119	arylsulfatase activity
GN309_RS09790	COG0745	RESPONSE REGULATOR receiver
GN309_RS09795	COG5002	protein histidine kinase activity
GN309_RS09815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GN309_RS09820	COG0248	Ppx GppA phosphatase
GN309_RS09830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GN309_RS09840	COG0356	it plays a direct role in the translocation of protons across the membrane
GN309_RS09845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN309_RS09850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GN309_RS09855	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GN309_RS09860	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GN309_RS09865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GN309_RS09880	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GN309_RS09890	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GN309_RS09895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GN309_RS09915	COG3973	AAA domain
GN309_RS09920	COG2855	membrane
GN309_RS09940	COG1979	alcohol dehydrogenase
GN309_RS09945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GN309_RS09960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GN309_RS09960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GN309_RS09965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GN309_RS09970	COG0357	Ribosomal RNA small subunit methyltransferase G
GN309_RS09980	COG2217	Heavy metal translocating P-type atpase
GN309_RS09995	COG0321	lipoyl(octanoyl) transferase activity
GN309_RS10000	COG1022	Amp-dependent synthetase and ligase
GN309_RS10005	COG1252	NADH dehydrogenase
GN309_RS10040	COG3617	BRO family, N-terminal domain
GN309_RS10060	COG4974	Belongs to the 'phage' integrase family
GN309_RS10100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GN309_RS10105	COG1523	belongs to the glycosyl hydrolase 13 family
GN309_RS10110	COG1312	Catalyzes the dehydration of D-mannonate
GN309_RS10115	COG1752	Esterase of the alpha-beta hydrolase superfamily
GN309_RS10120	COG2176	DNA-directed DNA polymerase activity
GN309_RS10125	COG1739	Uncharacterized protein family UPF0029
GN309_RS10135	COG0556	nucleotide-excision repair
GN309_RS10160	COG3942	CHAP domain
GN309_RS10160	COG1388	LysM domain
GN309_RS10170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GN309_RS10175	COG3104	oligopeptide transport
GN309_RS10180	COG2431	L-lysine efflux transmembrane transporter activity
GN309_RS10195	COG1757	Na H antiporter
GN309_RS10200	COG2721	sulfolactate sulfo-lyase activity
GN309_RS10205	COG1609	Transcriptional regulator
GN309_RS10220	COG0501	Belongs to the peptidase M48B family
GN309_RS10230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GN309_RS10240	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GN309_RS10255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GN309_RS10295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GN309_RS10310	COG1904	glucuronate isomerase
GN309_RS10315	COG0246	Mannitol dehydrogenase
GN309_RS10335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GN309_RS10340	COG1120	ATPase activity
GN309_RS10345	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GN309_RS10375	COG2207	Transcriptional regulator
GN309_RS10375	COG0662	Cupin 2, conserved barrel domain protein
GN309_RS10380	COG4753	response regulator
GN309_RS10380	COG2207	Transcriptional regulator
GN309_RS10385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GN309_RS10395	COG4771	TonB-dependent receptor
GN309_RS10405	COG4771	TonB-dependent receptor
GN309_RS10410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GN309_RS10415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GN309_RS10420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GN309_RS10440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN309_RS10450	COG0439	Biotin carboxylase
GN309_RS10475	COG4771	TonB-dependent receptor
GN309_RS10480	COG4771	TonB-dependent receptor
GN309_RS10490	COG1797	cobyrinic acid a,c-diamide synthase activity
GN309_RS10495	COG2096	Adenosyltransferase
GN309_RS10500	COG1492	cobalamin metabolic process
GN309_RS10510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GN309_RS10535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GN309_RS10570	COG0513	Belongs to the DEAD box helicase family
GN309_RS10575	COG3830	Belongs to the UPF0237 family
GN309_RS10575	COG0560	Phosphoserine phosphatase
GN309_RS10585	COG1011	Hydrolase
GN309_RS10595	COG0343	queuine tRNA-ribosyltransferase activity
GN309_RS10600	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GN309_RS10605	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GN309_RS10610	COG1597	lipid kinase activity
GN309_RS10615	COG0156	8-amino-7-oxononanoate synthase activity
GN309_RS10630	COG1136	(ABC) transporter
GN309_RS10675	COG3852	Histidine kinase
GN309_RS10690	COG4771	TonB-dependent receptor
GN309_RS10760	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GN309_RS10765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GN309_RS10800	COG3579	cysteine-type endopeptidase activity
GN309_RS10810	COG2244	polysaccharide biosynthetic process
GN309_RS10830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GN309_RS10835	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS10875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GN309_RS10900	COG1805	sodium ion transport
GN309_RS10905	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN309_RS10910	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN309_RS10915	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GN309_RS10925	COG0513	Belongs to the DEAD box helicase family
GN309_RS10930	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GN309_RS10935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GN309_RS10950	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS10965	COG0561	phosphatase activity
GN309_RS10975	COG1285	pathogenesis
GN309_RS10985	COG2205	protein histidine kinase activity
GN309_RS10995	COG0494	nUDIX hydrolase
GN309_RS11005	COG1733	regulation of RNA biosynthetic process
GN309_RS11010	COG4106	trans-aconitate 2-methyltransferase activity
GN309_RS11030	COG3387	PFAM Glycoside hydrolase 15-related
GN309_RS11060	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GN309_RS11065	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GN309_RS11070	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GN309_RS11080	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GN309_RS11085	COG2204	response regulator
GN309_RS11095	COG4176	ABC-type proline glycine betaine transport system permease component
GN309_RS11105	COG0697	spore germination
GN309_RS11110	COG0110	maltose O-acetyltransferase activity
GN309_RS11120	COG0024	Methionine aminopeptidase
GN309_RS11125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GN309_RS11135	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GN309_RS11140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GN309_RS11150	COG0552	protein localization to endoplasmic reticulum
GN309_RS11155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN309_RS11160	COG0776	regulation of translation
GN309_RS11165	COG0776	regulation of translation
GN309_RS11170	COG0714	Associated with various cellular activities
GN309_RS11185	COG2304	oxidoreductase activity
GN309_RS11210	COG0671	phosphoesterase, PA-phosphatase related
GN309_RS11235	COG0542	response to heat
GN309_RS11245	COG1752	Esterase of the alpha-beta hydrolase superfamily
GN309_RS11265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GN309_RS11270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GN309_RS11275	COG0336	Belongs to the RNA methyltransferase TrmD family
GN309_RS11280	COG0167	dihydroorotate dehydrogenase activity
GN309_RS11285	COG0543	2 iron, 2 sulfur cluster binding
GN309_RS11300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GN309_RS11315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GN309_RS11325	COG0390	transport system, permease component
GN309_RS11330	COG1131	(ABC) transporter
GN309_RS11335	COG0442	prolyl-tRNA aminoacylation
GN309_RS11345	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GN309_RS11375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GN309_RS11395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS11400	COG1131	(ABC) transporter
GN309_RS11405	COG0842	Transport permease protein
GN309_RS11410	COG0842	Transport permease protein
GN309_RS11410	COG1129	ABC transporter
GN309_RS11415	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GN309_RS11430	COG0540	Belongs to the ATCase OTCase family
GN309_RS11435	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GN309_RS11450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GN309_RS11455	COG0534	Mate efflux family protein
GN309_RS11460	COG2885	chlorophyll binding
GN309_RS11465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GN309_RS11500	COG0504	CTP synthase activity
GN309_RS11505	COG0706	membrane insertase activity
GN309_RS11510	COG1506	peptidase
GN309_RS11510	COG0823	Involved in the tonB-independent uptake of proteins
GN309_RS11515	COG0564	pseudouridine synthase activity
GN309_RS11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GN309_RS11525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GN309_RS11525	COG0574	Belongs to the PEP-utilizing enzyme family
GN309_RS11530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GN309_RS11545	COG0577	efflux transmembrane transporter activity
GN309_RS11545	COG1136	(ABC) transporter
GN309_RS11555	COG0339	signal peptide processing
GN309_RS11585	COG1216	Glycosyl transferase, family 2
GN309_RS11585	COG1442	glycosyl transferase family 8
GN309_RS11595	COG0438	transferase activity, transferring glycosyl groups
GN309_RS11610	COG1216	Glycosyl transferase, family 2
GN309_RS11640	COG0386	Belongs to the glutathione peroxidase family
GN309_RS11650	COG4191	Histidine kinase
GN309_RS11665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GN309_RS11670	COG0305	Participates in initiation and elongation during chromosome replication
GN309_RS11675	COG0072	phenylalanine-tRNA ligase activity
GN309_RS11675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN309_RS11680	COG0217	transcriptional regulatory protein
GN309_RS11700	COG0577	efflux transmembrane transporter activity
GN309_RS11705	COG0577	efflux transmembrane transporter activity
GN309_RS11705	COG1136	(ABC) transporter
GN309_RS11745	COG0010	Belongs to the arginase family
GN309_RS11750	COG0058	SHG alpha-glucan phosphorylase activity
GN309_RS11755	COG4651	solute:proton antiporter activity
GN309_RS11755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GN309_RS11760	COG0205	6-phosphofructokinase activity
GN309_RS11775	COG0588	phosphoglycerate mutase activity
GN309_RS11780	COG1830	Aldolase
GN309_RS11790	COG2095	MarC family integral membrane protein
GN309_RS11810	COG0655	NAD(P)H dehydrogenase (quinone) activity
GN309_RS11820	COG0667	Aldo Keto reductase
GN309_RS11840	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GN309_RS11845	COG4771	TonB-dependent receptor
GN309_RS11855	COG2706	6-phosphogluconolactonase activity
GN309_RS11860	COG2207	Transcriptional regulator
GN309_RS11910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS11920	COG0562	UDP-galactopyranose mutase
GN309_RS11930	COG1215	transferase activity, transferring glycosyl groups
GN309_RS11945	COG1216	Glycosyl transferase, family 2
GN309_RS11970	COG0488	(ABC) transporter
GN309_RS11995	COG0251	oxidation-reduction process
GN309_RS12010	COG1501	Belongs to the glycosyl hydrolase 31 family
GN309_RS12070	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GN309_RS12090	COG0776	regulation of translation
GN309_RS12235	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
GN309_RS12350	COG1629	transport
GN309_RS12365	COG4771	TonB-dependent receptor
GN309_RS12405	COG1629	transport
GN309_RS12405	COG4206	TonB-dependent receptor
GN309_RS12415	COG3292	Two component regulator propeller
GN309_RS12415	COG2205	protein histidine kinase activity
GN309_RS12415	COG0745	RESPONSE REGULATOR receiver
GN309_RS12425	COG2183	response to ionizing radiation
GN309_RS12430	COG2816	NAD+ diphosphatase activity
GN309_RS12440	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GN309_RS12445	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GN309_RS12450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GN309_RS12455	COG0297	glycogen (starch) synthase activity
GN309_RS12485	COG0497	DNA recombination
GN309_RS12490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GN309_RS12505	COG1918	ferrous iron import across plasma membrane
GN309_RS12505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GN309_RS12515	COG0259	pyridoxamine-phosphate oxidase activity
GN309_RS12540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GN309_RS12555	COG1139	Iron-sulfur cluster binding protein
GN309_RS12560	COG0247	lactate metabolic process
GN309_RS12565	COG4566	intracellular signal transduction
GN309_RS12580	COG3279	Response regulator of the LytR AlgR family
GN309_RS12590	COG0577	efflux transmembrane transporter activity
GN309_RS12590	COG1136	(ABC) transporter
GN309_RS12595	COG1136	(ABC) transporter
GN309_RS12600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS12615	COG1271	oxidase subunit
GN309_RS12625	COG0363	glucosamine-6-phosphate deaminase activity
GN309_RS12630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GN309_RS12635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GN309_RS12660	COG0252	asparaginase activity
GN309_RS12665	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GN309_RS12675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GN309_RS12680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GN309_RS12685	COG1119	ATPase activity
GN309_RS12690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GN309_RS12695	COG0436	Aminotransferase
GN309_RS12705	COG0347	Belongs to the P(II) protein family
GN309_RS12710	COG0004	ammonium transporteR
GN309_RS12725	COG2226	methyltransferase
GN309_RS12740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN309_RS12740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GN309_RS12745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GN309_RS12745	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GN309_RS12760	COG0438	transferase activity, transferring glycosyl groups
GN309_RS12775	COG1730	sister chromatid segregation
GN309_RS12795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GN309_RS12795	COG1333	cytochrome c biogenesis protein
GN309_RS12800	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GN309_RS12835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GN309_RS12840	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GN309_RS12865	COG0657	acetylesterase activity
GN309_RS12865	COG2755	lipolytic protein G-D-S-L family
GN309_RS12875	COG0228	four-way junction DNA binding
GN309_RS12945	COG0488	(ABC) transporter
GN309_RS12955	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GN309_RS12965	COG0534	Mate efflux family protein
GN309_RS12970	COG3263	regulation of cellular component size
GN309_RS12975	COG1914	H( )-stimulated, divalent metal cation uptake system
GN309_RS12995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GN309_RS13000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GN309_RS13005	COG3059	membrane
GN309_RS13015	COG0784	Response regulator, receiver
GN309_RS13015	COG2205	protein histidine kinase activity
GN309_RS13030	COG3408	Glycogen debranching enzyme
GN309_RS13040	COG1509	lysine 2,3-aminomutase activity
GN309_RS13045	COG4771	TonB-dependent receptor
GN309_RS13055	COG0737	Belongs to the 5'-nucleotidase family
GN309_RS13065	COG0484	heat shock protein binding
GN309_RS13085	COG1295	ribonuclease BN
GN309_RS13090	COG0307	riboflavin synthase, alpha
GN309_RS13100	COG0318	PFAM AMP-dependent synthetase and ligase
GN309_RS13105	COG0668	transmembrane transport
GN309_RS13130	COG2205	protein histidine kinase activity
GN309_RS13150	COG1620	l-lactate permease
GN309_RS13155	COG2873	o-acetylhomoserine
GN309_RS13165	COG4771	TonB-dependent receptor
GN309_RS13175	COG0306	phosphate transporter
GN309_RS13185	COG0586	Pfam SNARE associated Golgi protein
GN309_RS13195	COG1522	sequence-specific DNA binding
GN309_RS13200	COG0598	Magnesium transport protein CorA
GN309_RS13230	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GN309_RS13280	COG1132	(ABC) transporter
GN309_RS13290	COG0489	protein tyrosine kinase activity
GN309_RS13290	COG3206	protein involved in exopolysaccharide biosynthesis
GN309_RS13320	COG1215	transferase activity, transferring glycosyl groups
GN309_RS13325	COG1216	Glycosyl transferase, family 2
GN309_RS13330	COG1216	Glycosyl transferase, family 2
GN309_RS13340	COG1231	oxidoreductase activity
GN309_RS13345	COG1442	glycosyl transferase family 8
GN309_RS13385	COG0438	transferase activity, transferring glycosyl groups
GN309_RS13390	COG0463	Glycosyl transferase, family 2
GN309_RS13395	COG1216	Glycosyl transferase, family 2
GN309_RS13400	COG0438	transferase activity, transferring glycosyl groups
GN309_RS13405	COG1216	Glycosyl transferase, family 2
GN309_RS13430	COG0110	maltose O-acetyltransferase activity
GN309_RS13435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GN309_RS13460	COG3940	Belongs to the glycosyl hydrolase 43 family
GN309_RS13465	COG3250	beta-galactosidase activity
GN309_RS13470	COG3250	beta-galactosidase activity
GN309_RS13480	COG4771	TonB-dependent receptor
GN309_RS13490	COG4206	TonB-dependent receptor
GN309_RS13490	COG1629	transport
GN309_RS13495	COG2985	domain, Protein
GN309_RS13495	COG0490	domain, Protein
GN309_RS13510	COG3250	beta-galactosidase activity
GN309_RS13615	COG0582	viral genome integration into host DNA
GN309_RS13645	COG1475	DNA binding
GN309_RS13735	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN309_RS13810	COG0739	heme binding
GN309_RS13820	COG1309	transcriptional regulator
GN309_RS13830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GN309_RS13885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GN309_RS13895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GN309_RS13915	COG0525	valine-tRNA ligase activity
GN309_RS13920	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS14005	COG4974	Belongs to the 'phage' integrase family
GN309_RS14010	COG4974	Belongs to the 'phage' integrase family
GN309_RS14040	COG0732	type I restriction modification DNA specificity domain
GN309_RS14055	COG0732	type I restriction modification DNA specificity domain
GN309_RS14060	COG4974	Belongs to the 'phage' integrase family
GN309_RS14095	COG4974	Belongs to the 'phage' integrase family
GN309_RS14100	COG4974	Belongs to the 'phage' integrase family
GN309_RS14155	COG0300	oxidoreductase activity
GN309_RS14155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GN309_RS14155	COG0318	PFAM AMP-dependent synthetase and ligase
GN309_RS14155	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS14155	COG3321	synthase
GN309_RS14190	COG2226	methyltransferase
GN309_RS14210	COG1132	(ABC) transporter
GN309_RS14225	COG4974	Belongs to the 'phage' integrase family
GN309_RS14415	COG4974	Belongs to the 'phage' integrase family
GN309_RS14435	COG3023	N-Acetylmuramoyl-L-alanine amidase
GN309_RS14480	COG1091	dTDP-4-dehydrorhamnose reductase activity
GN309_RS14510	COG3754	Rhamnan synthesis protein F
GN309_RS14520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN309_RS14545	COG0110	maltose O-acetyltransferase activity
GN309_RS14550	COG1216	Glycosyl transferase, family 2
GN309_RS14570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GN309_RS14575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS14580	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GN309_RS14580	COG0662	Cupin 2, conserved barrel domain protein
GN309_RS14605	COG3408	Glycogen debranching enzyme
GN309_RS14615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS14625	COG0148	phosphopyruvate hydratase activity
GN309_RS14635	COG0514	ATP-dependent DNA helicase (RecQ)
GN309_RS14650	COG0463	Glycosyl transferase, family 2
GN309_RS14665	COG1971	Probably functions as a manganese efflux pump
GN309_RS14670	COG1477	protein flavinylation
GN309_RS14685	COG0339	signal peptide processing
GN309_RS14695	COG2131	deaminase
GN309_RS14700	COG0793	Belongs to the peptidase S41A family
GN309_RS14715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GN309_RS14725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GN309_RS14740	COG1741	Belongs to the pirin family
GN309_RS14755	COG0708	Exodeoxyribonuclease III
GN309_RS14775	COG2204	response regulator
GN309_RS14785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GN309_RS14790	COG0738	Major facilitator superfamily
GN309_RS14815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN309_RS14820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GN309_RS14830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GN309_RS14835	COG1215	transferase activity, transferring glycosyl groups
GN309_RS14875	COG3275	phosphorelay sensor kinase activity
GN309_RS14895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GN309_RS14905	COG0539	negative regulation of cytoplasmic translation
GN309_RS14915	COG1234	tRNA 3'-trailer cleavage
GN309_RS14920	COG1595	DNA-templated transcription, initiation
GN309_RS14935	COG4771	TonB-dependent receptor
GN309_RS14945	COG3956	TIGRFAM MazG family protein
GN309_RS14950	COG0525	valine-tRNA ligase activity
GN309_RS14980	COG0653	protein targeting
GN309_RS14995	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GN309_RS15015	COG1253	flavin adenine dinucleotide binding
GN309_RS15040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GN309_RS15060	COG0129	dihydroxy-acid dehydratase activity
GN309_RS15070	COG1047	Peptidyl-prolyl cis-trans
GN309_RS15085	COG0101	tRNA pseudouridine synthase activity
GN309_RS15095	COG1702	phosphate starvation-inducible protein PhoH
GN309_RS15100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GN309_RS15105	COG2226	methyltransferase
GN309_RS15110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GN309_RS15125	COG1704	LemA family
GN309_RS15130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GN309_RS15140	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GN309_RS15140	COG0778	Nitroreductase
GN309_RS15155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GN309_RS15160	COG2233	PERMEase
GN309_RS15170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GN309_RS15175	COG1410	methionine synthase
GN309_RS15175	COG0646	methionine synthase
GN309_RS15180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GN309_RS15270	COG0768	penicillin binding
GN309_RS15335	COG1132	(ABC) transporter
GN309_RS15340	COG2226	methyltransferase
GN309_RS15340	COG0596	Alpha beta hydrolase
GN309_RS15340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GN309_RS15350	COG1309	transcriptional regulator
GN309_RS15355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS15360	COG2814	Major facilitator Superfamily
GN309_RS15375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GN309_RS15380	COG0424	maF-like protein
GN309_RS15385	COG0561	phosphatase activity
GN309_RS15400	COG0778	Nitroreductase
GN309_RS15415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN309_RS15425	COG0511	ligase activity, forming carbon-carbon bonds
GN309_RS15430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GN309_RS15440	COG4221	oxidoreductase activity
GN309_RS15450	COG2217	Heavy metal translocating P-type atpase
GN309_RS15460	COG2755	lipolytic protein G-D-S-L family
GN309_RS15460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GN309_RS15485	COG1193	negative regulation of DNA recombination
GN309_RS15490	COG0582	viral genome integration into host DNA
GN309_RS15500	COG2226	methyltransferase
GN309_RS15525	COG4771	TonB-dependent receptor
GN309_RS15545	COG1760	l-serine dehydratase
GN309_RS15560	COG0569	domain protein
GN309_RS15565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GN309_RS15570	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GN309_RS15575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GN309_RS15590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS15600	COG4771	TonB-dependent receptor
GN309_RS15610	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GN309_RS15625	COG0446	pyridine nucleotide-disulphide oxidoreductase
GN309_RS15630	COG0534	Mate efflux family protein
GN309_RS15635	COG0471	metal ion transport
GN309_RS15635	COG0490	domain, Protein
GN309_RS15640	COG2050	protein possibly involved in aromatic compounds catabolism
GN309_RS15645	COG1169	isochorismate synthase
GN309_RS15650	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GN309_RS15655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GN309_RS15665	COG4948	Mandelate Racemase Muconate Lactonizing
GN309_RS15685	COG0556	nucleotide-excision repair
GN309_RS15745	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GN309_RS15765	COG0438	transferase activity, transferring glycosyl groups
GN309_RS15780	COG0438	transferase activity, transferring glycosyl groups
GN309_RS15785	COG1216	Glycosyl transferase, family 2
GN309_RS15870	COG0443	Heat shock 70 kDa protein
GN309_RS15890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN309_RS15895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GN309_RS15910	COG4771	TonB-dependent receptor
GN309_RS15920	COG0745	RESPONSE REGULATOR receiver
GN309_RS15920	COG3292	Two component regulator propeller
GN309_RS15920	COG2205	protein histidine kinase activity
GN309_RS15925	COG0157	Belongs to the NadC ModD family
GN309_RS15930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GN309_RS15940	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN309_RS15955	COG3118	belongs to the thioredoxin family
GN309_RS15965	COG1773	rubredoxin
GN309_RS15965	COG1592	Rubrerythrin
GN309_RS15980	COG0131	Imidazoleglycerol-phosphate dehydratase
GN309_RS15985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GN309_RS15990	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GN309_RS15995	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GN309_RS16010	COG0572	uridine kinase
GN309_RS16015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GN309_RS16050	COG4191	Histidine kinase
GN309_RS16055	COG2204	response regulator
GN309_RS16080	COG1136	(ABC) transporter
GN309_RS16080	COG0577	efflux transmembrane transporter activity
GN309_RS16090	COG1136	(ABC) transporter
GN309_RS16090	COG0577	efflux transmembrane transporter activity
GN309_RS16100	COG0577	efflux transmembrane transporter activity
GN309_RS16105	COG1136	(ABC) transporter
GN309_RS16115	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN309_RS16115	COG1388	LysM domain
GN309_RS16150	COG0393	Putative heavy-metal-binding
GN309_RS16170	COG0488	(ABC) transporter
GN309_RS16175	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GN309_RS16180	COG0484	heat shock protein binding
GN309_RS16200	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GN309_RS16225	COG2160	L-arabinose isomerase activity
GN309_RS16235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GN309_RS16285	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GN309_RS16290	COG0673	inositol 2-dehydrogenase activity
GN309_RS16330	COG2264	protein methyltransferase activity
GN309_RS16360	COG5434	Belongs to the glycosyl hydrolase 28 family
GN309_RS16375	COG1032	radical SAM domain protein
GN309_RS16395	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GN309_RS16405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GN309_RS16425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GN309_RS16435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GN309_RS16440	COG2311	Membrane
GN309_RS16485	COG0463	Glycosyl transferase, family 2
GN309_RS16490	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GN309_RS16495	COG0646	methionine synthase
GN309_RS16495	COG1410	methionine synthase
GN309_RS16500	COG1408	metallophosphoesterase
GN309_RS16515	COG3591	Belongs to the peptidase S1B family
GN309_RS16520	COG3591	Belongs to the peptidase S1B family
GN309_RS16535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GN309_RS16540	COG4413	Urea transporter
GN309_RS16555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GN309_RS16565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GN309_RS16575	COG1834	amidinotransferase
GN309_RS16580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GN309_RS16585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GN309_RS16585	COG0321	lipoyl(octanoyl) transferase activity
GN309_RS16600	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GN309_RS16625	COG4974	Belongs to the 'phage' integrase family
GN309_RS16730	COG0513	Belongs to the DEAD box helicase family
GN309_RS16740	COG2244	polysaccharide biosynthetic process
GN309_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS16790	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GN309_RS16825	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GN309_RS16835	COG1091	dTDP-4-dehydrorhamnose reductase activity
GN309_RS16855	COG4372	Transposase
GN309_RS16925	COG4771	TonB-dependent receptor
GN309_RS16930	COG0745	RESPONSE REGULATOR receiver
GN309_RS16930	COG3292	Two component regulator propeller
GN309_RS16930	COG2205	protein histidine kinase activity
GN309_RS16945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS16950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS16960	COG1629	transport
GN309_RS16985	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GN309_RS16990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GN309_RS16995	COG0534	Mate efflux family protein
GN309_RS17015	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS17025	COG0126	phosphoglycerate kinase activity
GN309_RS17035	COG4206	TonB-dependent receptor
GN309_RS17035	COG1629	transport
GN309_RS17120	COG4771	TonB-dependent receptor
GN309_RS17145	COG3292	Two component regulator propeller
GN309_RS17145	COG2205	protein histidine kinase activity
GN309_RS17145	COG0745	RESPONSE REGULATOR receiver
GN309_RS17150	COG3250	beta-galactosidase activity
GN309_RS17155	COG0702	epimerase
GN309_RS17160	COG4771	TonB-dependent receptor
GN309_RS17210	COG3275	phosphorelay sensor kinase activity
GN309_RS17390	COG4974	Belongs to the 'phage' integrase family
GN309_RS17400	COG4804	nuclease activity
GN309_RS17455	COG3681	Belongs to the UPF0597 family
GN309_RS17465	COG3292	Two component regulator propeller
GN309_RS17465	COG0745	RESPONSE REGULATOR receiver
GN309_RS17465	COG2205	protein histidine kinase activity
GN309_RS17475	COG1115	amino acid carrier protein
GN309_RS17495	COG0602	queuosine metabolic process
GN309_RS17505	COG2832	Protein of unknown function (DUF454)
GN309_RS17520	COG1418	mRNA catabolic process
GN309_RS17535	COG0006	proline dipeptidase activity
GN309_RS17545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GN309_RS17545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GN309_RS17550	COG0514	ATP-dependent DNA helicase (RecQ)
GN309_RS17555	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GN309_RS17565	COG0628	permease
GN309_RS17570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GN309_RS17580	COG1733	regulation of RNA biosynthetic process
GN309_RS17590	COG0436	Aminotransferase
GN309_RS17595	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GN309_RS17615	COG1073	alpha beta
GN309_RS17640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GN309_RS17645	COG1120	ATPase activity
GN309_RS17650	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GN309_RS17655	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GN309_RS17670	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GN309_RS17680	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GN309_RS17685	COG0716	FMN binding
GN309_RS17690	COG0022	dehydrogenase e1 component
GN309_RS17695	COG0508	dehydrogenase complex catalyzes the overall conversion of
GN309_RS17700	COG0095	Lipoate-protein ligase
GN309_RS17715	COG4771	TonB-dependent receptor
GN309_RS17725	COG0826	peptidase U32
GN309_RS17730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GN309_RS17735	COG0673	inositol 2-dehydrogenase activity
GN309_RS17750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS17760	COG3590	peptidase
GN309_RS17765	COG0488	(ABC) transporter
GN309_RS17780	COG4771	TonB-dependent receptor
GN309_RS17795	COG2755	lipolytic protein G-D-S-L family
GN309_RS17810	COG4206	TonB-dependent receptor
GN309_RS17810	COG1629	transport
GN309_RS17820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GN309_RS17825	COG0735	belongs to the Fur family
GN309_RS17845	COG0514	ATP-dependent DNA helicase (RecQ)
GN309_RS17855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GN309_RS17865	COG0473	3-isopropylmalate dehydrogenase activity
GN309_RS17870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN309_RS17875	COG0066	3-isopropylmalate dehydratase activity
GN309_RS17880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GN309_RS17885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GN309_RS17945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GN309_RS17950	COG0009	L-threonylcarbamoyladenylate synthase
GN309_RS17955	COG0668	transmembrane transport
GN309_RS17960	COG0426	domain, Protein
GN309_RS17965	COG1242	4 iron, 4 sulfur cluster binding
GN309_RS17970	COG0823	Involved in the tonB-independent uptake of proteins
GN309_RS17970	COG1506	peptidase
GN309_RS17975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GN309_RS17995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GN309_RS18025	COG4771	TonB-dependent receptor
GN309_RS18030	COG0561	phosphatase activity
GN309_RS18040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GN309_RS18045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GN309_RS18050	COG0511	ligase activity, forming carbon-carbon bonds
GN309_RS18065	COG0546	phosphoglycolate phosphatase activity
GN309_RS18070	COG0205	6-phosphofructokinase activity
GN309_RS18100	COG1902	pentaerythritol trinitrate reductase activity
GN309_RS18115	COG0372	Belongs to the citrate synthase family
GN309_RS18120	COG0538	isocitrate dehydrogenase activity
GN309_RS18125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GN309_RS18150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GN309_RS18150	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GN309_RS18160	COG1595	DNA-templated transcription, initiation
GN309_RS18170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GN309_RS18180	COG1522	sequence-specific DNA binding
GN309_RS18210	COG0811	peptide transport
GN309_RS18220	COG0084	hydrolase, TatD family'
GN309_RS18235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GN309_RS18240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GN309_RS18245	COG0205	6-phosphofructokinase activity
GN309_RS18265	COG2373	Large extracellular alpha-helical protein
GN309_RS18270	COG3550	peptidyl-serine autophosphorylation
GN309_RS18280	COG1396	sequence-specific DNA binding
GN309_RS18285	COG0590	tRNA wobble adenosine to inosine editing
GN309_RS18290	COG2195	Cleaves the N-terminal amino acid of tripeptides
GN309_RS18300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GN309_RS18305	COG2239	Acts as a magnesium transporter
GN309_RS18310	COG1196	nuclear chromosome segregation
GN309_RS18325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GN309_RS18340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GN309_RS18345	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GN309_RS18350	COG1192	Involved in chromosome partitioning
GN309_RS18355	COG1475	DNA binding
GN309_RS18365	COG1705	Flagellar rod assembly protein muramidase FlgJ
GN309_RS18365	COG1388	LysM domain
GN309_RS18370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GN309_RS18380	COG0739	heme binding
GN309_RS18385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GN309_RS18405	COG0742	ribosomal rna small subunit methyltransferase
GN309_RS18410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GN309_RS18425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GN309_RS18545	COG0475	glutathione-regulated potassium exporter activity
GN309_RS18560	COG0588	phosphoglycerate mutase activity
GN309_RS18565	COG1830	Aldolase
GN309_RS18580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GN309_RS18585	COG0802	atpase or kinase
GN309_RS18615	COG0688	phosphatidylethanolamine metabolic process
GN309_RS18620	COG1183	phosphatidylcholine synthase activity
GN309_RS18640	COG0792	nuclease activity
GN309_RS18650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GN309_RS18650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GN309_RS18660	COG0534	Mate efflux family protein
GN309_RS18665	COG0528	UMP kinase activity
GN309_RS18670	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS18690	COG0233	cytoplasmic translational termination
GN309_RS18695	COG1162	GTPase activity
GN309_RS18705	COG1566	PFAM secretion protein HlyD family protein
GN309_RS18710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GN309_RS18720	COG0531	amino acid
GN309_RS18730	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GN309_RS18730	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GN309_RS18745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GN309_RS18755	COG4771	TonB-dependent receptor
GN309_RS18765	COG1629	transport
GN309_RS18765	COG4206	TonB-dependent receptor
GN309_RS18780	COG4206	TonB-dependent receptor
GN309_RS18780	COG1629	transport
GN309_RS18785	COG4974	Belongs to the 'phage' integrase family
GN309_RS18790	COG1629	transport
GN309_RS18810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GN309_RS18815	COG1435	thymidine kinase activity
GN309_RS18820	COG0628	permease
GN309_RS18840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GN309_RS18845	COG0470	DNA polymerase III
GN309_RS18850	COG1774	PSP1 C-terminal conserved region
GN309_RS18860	COG0772	Belongs to the SEDS family
GN309_RS18865	COG0768	penicillin binding
GN309_RS18885	COG0138	bifunctional purine biosynthesis protein purh
GN309_RS18900	COG1506	peptidase
GN309_RS18900	COG0823	Involved in the tonB-independent uptake of proteins
GN309_RS18910	COG0745	RESPONSE REGULATOR receiver
GN309_RS18910	COG3292	Two component regulator propeller
GN309_RS18910	COG2205	protein histidine kinase activity
GN309_RS18915	COG2755	lipolytic protein G-D-S-L family
GN309_RS18930	COG1917	Cupin 2, conserved barrel domain protein
GN309_RS18960	COG4771	TonB-dependent receptor
GN309_RS18990	COG3507	Belongs to the glycosyl hydrolase 43 family
GN309_RS18995	COG0702	epimerase
GN309_RS19000	COG4771	TonB-dependent receptor
GN309_RS19005	COG0515	serine threonine protein kinase
GN309_RS19005	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GN309_RS19015	COG1629	transport
GN309_RS19020	COG4677	pectinesterase activity
GN309_RS19025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS19030	COG3775	system Galactitol-specific IIC component
GN309_RS19035	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GN309_RS19040	COG2271	Major facilitator Superfamily
GN309_RS19065	COG1012	belongs to the aldehyde dehydrogenase family
GN309_RS19070	COG3292	Two component regulator propeller
GN309_RS19070	COG2205	protein histidine kinase activity
GN309_RS19070	COG0745	RESPONSE REGULATOR receiver
GN309_RS19085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS19095	COG1629	transport
GN309_RS19110	COG3940	Belongs to the glycosyl hydrolase 43 family
GN309_RS19110	COG3940	Belongs to the glycosyl hydrolase 43 family
GN309_RS19120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS19125	COG3250	beta-galactosidase activity
GN309_RS19135	COG3292	Two component regulator propeller
GN309_RS19135	COG2205	protein histidine kinase activity
GN309_RS19135	COG0745	RESPONSE REGULATOR receiver
GN309_RS19150	COG3250	beta-galactosidase activity
GN309_RS19160	COG4771	TonB-dependent receptor
GN309_RS19200	COG1629	transport
GN309_RS19200	COG4206	TonB-dependent receptor
GN309_RS19235	COG1629	transport
GN309_RS19235	COG4206	TonB-dependent receptor
GN309_RS19240	COG0702	epimerase
GN309_RS19245	COG3119	arylsulfatase activity
GN309_RS19260	COG3250	beta-galactosidase activity
GN309_RS19275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GN309_RS19285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GN309_RS19290	COG0569	domain protein
GN309_RS19295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GN309_RS19300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN309_RS19305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN309_RS19310	COG0649	NAD binding
GN309_RS19315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GN309_RS19320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN309_RS19325	COG0839	Belongs to the complex I subunit 6 family
GN309_RS19335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GN309_RS19340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GN309_RS19345	COG1007	ATP synthesis coupled electron transport
GN309_RS19350	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GN309_RS19355	COG5002	protein histidine kinase activity
GN309_RS19360	COG2205	protein histidine kinase activity
GN309_RS19360	COG3850	Histidine kinase
GN309_RS19360	COG3437	response regulator, receiver
GN309_RS19360	COG4999	Histidine kinase
GN309_RS19380	COG2205	protein histidine kinase activity
GN309_RS19380	COG3292	Two component regulator propeller
GN309_RS19380	COG0745	RESPONSE REGULATOR receiver
GN309_RS19385	COG4771	TonB-dependent receptor
GN309_RS19400	COG0523	cobalamin synthesis protein
GN309_RS19415	COG2706	6-phosphogluconolactonase activity
GN309_RS19420	COG1482	cell wall glycoprotein biosynthetic process
GN309_RS19465	COG0138	bifunctional purine biosynthesis protein purh
GN309_RS19505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN309_RS19510	COG0563	adenylate kinase activity
GN309_RS19520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GN309_RS19520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GN309_RS19565	COG0191	fructose-bisphosphate aldolase activity
GN309_RS19570	COG0254	rRNA binding
GN309_RS19580	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GN309_RS19590	COG2205	protein histidine kinase activity
GN309_RS19590	COG3292	Two component regulator propeller
GN309_RS19590	COG0745	RESPONSE REGULATOR receiver
GN309_RS19595	COG1105	Belongs to the carbohydrate kinase PfkB family
GN309_RS19605	COG1621	beta-fructofuranosidase activity
GN309_RS19620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GN309_RS19625	COG0673	inositol 2-dehydrogenase activity
GN309_RS19630	COG0632	four-way junction helicase activity
GN309_RS19640	COG0617	tRNA 3'-terminal CCA addition
GN309_RS19645	COG1272	protein, Hemolysin III
GN309_RS19660	COG0750	zinc metalloprotease
GN309_RS19665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GN309_RS19670	COG0739	heme binding
GN309_RS19675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GN309_RS19680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GN309_RS19690	COG1214	PFAM Peptidase M22, glycoprotease
GN309_RS19700	COG0194	GDP metabolic process
GN309_RS19710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GN309_RS19720	COG1408	metallophosphoesterase
GN309_RS19725	COG1575	Belongs to the MenA family. Type 1 subfamily
GN309_RS19730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GN309_RS19735	COG0179	Fumarylacetoacetate (FAA) hydrolase
GN309_RS19740	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GN309_RS19750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GN309_RS19755	COG0052	Belongs to the universal ribosomal protein uS2 family
GN309_RS19760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GN309_RS19765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GN309_RS19785	COG0017	Asparaginyl-tRNA synthetase
GN309_RS19790	COG1187	pseudouridine synthase activity
GN309_RS19800	COG0534	Mate efflux family protein
GN309_RS19820	COG1131	(ABC) transporter
GN309_RS19850	COG0811	peptide transport
GN309_RS19900	COG0616	signal peptide processing
GN309_RS19905	COG1663	tetraacyldisaccharide 4'-kinase activity
GN309_RS19910	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GN309_RS19915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GN309_RS19950	COG3385	transposase activity
GN309_RS20100	COG3385	transposase activity
GN309_RS20115	COG1192	Involved in chromosome partitioning
GN309_RS20125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS20130	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GN309_RS20170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GN309_RS20210	COG1785	Belongs to the alkaline phosphatase family
GN309_RS20220	COG0733	neurotransmitter:sodium symporter activity
GN309_RS20240	COG2954	triphosphatase activity
GN309_RS20250	COG1022	Amp-dependent synthetase and ligase
GN309_RS20295	COG1519	Transferase
GN309_RS20300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GN309_RS20310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GN309_RS20315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GN309_RS20320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GN309_RS20335	COG2096	Adenosyltransferase
GN309_RS20350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GN309_RS20360	COG0439	Biotin carboxylase
GN309_RS20365	COG3189	MarR family transcriptional regulator
GN309_RS20485	COG0667	Aldo Keto reductase
GN309_RS20490	COG0165	Argininosuccinate lyase
GN309_RS20500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GN309_RS20505	COG1040	competence protein
GN309_RS20515	COG2890	protein-(glutamine-N5) methyltransferase activity
GN309_RS20520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GN309_RS20520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GN309_RS20530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GN309_RS20550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GN309_RS20565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GN309_RS20580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GN309_RS20585	COG4974	Belongs to the 'phage' integrase family
GN309_RS20830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN309_RS20830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GN309_RS20855	COG3475	LICD family
GN309_RS20870	COG0438	transferase activity, transferring glycosyl groups
GN309_RS20885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GN309_RS20890	COG1854	S-ribosylhomocysteine lyase activity
GN309_RS20895	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GN309_RS20950	COG0745	RESPONSE REGULATOR receiver
GN309_RS20950	COG2205	protein histidine kinase activity
GN309_RS20950	COG3292	Two component regulator propeller
GN309_RS20965	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GN309_RS20970	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GN309_RS20975	COG1013	pyruvate-flavodoxin oxidoreductase activity
GN309_RS20980	COG0674	pyruvate-flavodoxin oxidoreductase activity
GN309_RS20980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GN309_RS21040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GN309_RS21045	COG3723	Recombinational DNA repair protein, rece pathway
GN309_RS21110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GN309_RS21370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GN309_RS21380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GN309_RS21385	COG0339	signal peptide processing
GN309_RS21405	COG0776	regulation of translation
GN309_RS21410	COG3250	beta-galactosidase activity
GN309_RS21420	COG0482	sulfurtransferase activity
GN309_RS21425	COG3119	arylsulfatase activity
GN309_RS21435	COG3507	Belongs to the glycosyl hydrolase 43 family
GN309_RS21440	COG2205	protein histidine kinase activity
GN309_RS21440	COG3292	Two component regulator propeller
GN309_RS21440	COG0745	RESPONSE REGULATOR receiver
GN309_RS21445	COG1082	Xylose isomerase domain protein TIM barrel
GN309_RS21450	COG1629	transport
GN309_RS21450	COG4206	TonB-dependent receptor
GN309_RS21470	COG0215	cysteine-tRNA ligase activity
GN309_RS21485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN309_RS21490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GN309_RS21525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN309_RS21555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GN309_RS21630	COG0205	6-phosphofructokinase activity
GN309_RS21635	COG2205	protein histidine kinase activity
GN309_RS21635	COG0745	RESPONSE REGULATOR receiver
GN309_RS21635	COG3292	Two component regulator propeller
GN309_RS21640	COG4206	TonB-dependent receptor
GN309_RS21640	COG1629	transport
GN309_RS21655	COG3119	arylsulfatase activity
GN309_RS21670	COG3119	arylsulfatase activity
GN309_RS21675	COG0571	ribonuclease III activity
GN309_RS21680	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GN309_RS21685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GN309_RS21690	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GN309_RS21700	COG1629	transport
GN309_RS21700	COG4206	TonB-dependent receptor
GN309_RS21760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GN309_RS21775	COG0562	UDP-galactopyranose mutase
GN309_RS21815	COG1132	(ABC) transporter
GN309_RS21825	COG1215	transferase activity, transferring glycosyl groups
GN309_RS21835	COG0463	Glycosyl transferase, family 2
GN309_RS21845	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GN309_RS21855	COG3341	Caulimovirus viroplasmin
GN309_RS21855	COG0328	RNA-DNA hybrid ribonuclease activity
GN309_RS21860	COG0018	arginyl-trna synthetase
GN309_RS21865	COG1629	transport
GN309_RS21875	COG0826	peptidase U32
GN309_RS21880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GN309_RS21900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GN309_RS21905	COG0557	exoribonuclease II activity
GN309_RS21910	COG1045	serine acetyltransferase
GN309_RS21915	COG4251	negative regulation of phosphorylation
GN309_RS21925	COG0783	Belongs to the Dps family
GN309_RS21930	COG0583	DNA-binding transcription factor activity
GN309_RS21940	COG0116	Belongs to the methyltransferase superfamily
GN309_RS21945	COG0823	Involved in the tonB-independent uptake of proteins
GN309_RS21945	COG1506	peptidase
GN309_RS21965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GN309_RS21965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GN309_RS21995	COG0726	polysaccharide deacetylase
GN309_RS22010	COG0561	phosphatase activity
GN309_RS22015	COG4771	TonB-dependent receptor
GN309_RS22020	COG4677	pectinesterase activity
GN309_RS22025	COG1028	Short-chain dehydrogenase reductase Sdr
GN309_RS22030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GN309_RS22035	COG2027	D-alanyl-D-alanine carboxypeptidase
GN309_RS22115	COG0358	DNA primase activity
GN309_RS22235	COG2205	protein histidine kinase activity
GN309_RS22235	COG2198	Histidine kinase
GN309_RS22235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GN309_RS22235	COG0784	Response regulator, receiver
GN309_RS22255	COG0551	DNA topoisomerase type I activity
GN309_RS22255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GN309_RS22290	COG4974	Belongs to the 'phage' integrase family
GN309_RS22295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GN309_RS22325	COG4948	Mandelate Racemase Muconate Lactonizing
GN309_RS22335	COG0702	epimerase
GN309_RS22340	COG4206	TonB-dependent receptor
GN309_RS22340	COG1629	transport
GN309_RS22370	COG1629	transport
GN309_RS22385	COG0745	RESPONSE REGULATOR receiver
GN309_RS22385	COG2205	protein histidine kinase activity
GN309_RS22385	COG3292	Two component regulator propeller
GN309_RS22390	COG1592	Rubrerythrin
GN309_RS22400	COG0659	secondary active sulfate transmembrane transporter activity
GN309_RS22415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GN309_RS22420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GN309_RS22455	COG5002	protein histidine kinase activity
GN309_RS22465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN309_RS22465	COG0731	radical SAM domain protein
GN309_RS22485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GN309_RS22490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GN309_RS22500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GN309_RS22505	COG0495	leucyl-tRNA aminoacylation
GN309_RS22510	COG3292	Two component regulator propeller
GN309_RS22510	COG0745	RESPONSE REGULATOR receiver
GN309_RS22510	COG2205	protein histidine kinase activity
GN309_RS22510	COG0745	RESPONSE REGULATOR receiver
GN309_RS22510	COG2205	protein histidine kinase activity
GN309_RS22510	COG3292	Two component regulator propeller
GN309_RS22515	COG3250	beta-galactosidase activity
GN309_RS22525	COG0702	epimerase
GN309_RS22530	COG0793	Belongs to the peptidase S41A family
GN309_RS22530	COG4946	Tricorn protease homolog
GN309_RS22535	COG1595	DNA-templated transcription, initiation
GN309_RS22545	COG4206	TonB-dependent receptor
GN309_RS22545	COG1629	transport
GN309_RS22555	COG3119	arylsulfatase activity
GN309_RS22560	COG3119	arylsulfatase activity
GN309_RS22570	COG1472	Belongs to the glycosyl hydrolase 3 family
GN309_RS22575	COG0427	acetyl-CoA hydrolase
GN309_RS22585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GN309_RS22590	COG0545	Peptidyl-prolyl cis-trans isomerase
GN309_RS22595	COG1983	PspC domain protein
GN309_RS22605	COG2177	Part of the ABC transporter FtsEX involved in
GN309_RS22615	COG1968	undecaprenyl-diphosphatase activity
GN309_RS22620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GN309_RS22625	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GN309_RS22630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GN309_RS22680	COG1629	transport
GN309_RS22680	COG4206	TonB-dependent receptor
GN309_RS22690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GN309_RS22705	COG2814	Major facilitator Superfamily
GN309_RS22710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GN309_RS22715	COG1611	Belongs to the LOG family
GN309_RS22730	COG0594	ribonuclease P activity
GN309_RS22735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GN309_RS22745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GN309_RS22795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GN309_RS22835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GN309_RS22845	COG0012	GTP binding
GN309_RS22855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GN309_RS22855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GN309_RS22860	COG0142	geranyltranstransferase activity
GN309_RS22870	COG1694	Mazg nucleotide pyrophosphohydrolase
GN309_RS22875	COG1490	D-aminoacyl-tRNA deacylase activity
GN309_RS22880	COG0322	excinuclease ABC activity
GN309_RS22885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis