locus-tag	class	description
E0L14_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
E0L14_RS00020	COG1640	4-alpha-glucanotransferase
E0L14_RS00030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E0L14_RS00035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS00060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E0L14_RS00065	COG1022	Amp-dependent synthetase and ligase
E0L14_RS00085	COG0359	binds to the 23S rRNA
E0L14_RS00090	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
E0L14_RS00095	COG0360	Binds together with S18 to 16S ribosomal RNA
E0L14_RS00120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E0L14_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E0L14_RS00150	COG4771	TonB-dependent receptor
E0L14_RS00165	COG2431	L-lysine efflux transmembrane transporter activity
E0L14_RS00180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS00205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E0L14_RS00210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
E0L14_RS00215	COG0386	Belongs to the glutathione peroxidase family
E0L14_RS00235	COG3275	phosphorelay sensor kinase activity
E0L14_RS00240	COG3279	Response regulator of the LytR AlgR family
E0L14_RS00260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E0L14_RS00275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E0L14_RS00285	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E0L14_RS00290	COG0658	competence protein
E0L14_RS00295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E0L14_RS00300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E0L14_RS00310	COG0009	L-threonylcarbamoyladenylate synthase
E0L14_RS00340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS00345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS00355	COG1216	Glycosyl transferase, family 2
E0L14_RS00365	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS00405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
E0L14_RS00410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E0L14_RS00450	COG2818	Glycosylase
E0L14_RS00460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E0L14_RS00460	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E0L14_RS00465	COG0514	ATP-dependent DNA helicase (RecQ)
E0L14_RS00475	COG2271	Major facilitator Superfamily
E0L14_RS00490	COG0702	epimerase
E0L14_RS00495	COG4771	TonB-dependent receptor
E0L14_RS00500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0L14_RS00505	COG2186	Transcriptional regulator
E0L14_RS00515	COG0436	Aminotransferase
E0L14_RS00520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E0L14_RS00535	COG0358	DNA primase activity
E0L14_RS00540	COG3119	arylsulfatase activity
E0L14_RS00555	COG4206	TonB-dependent receptor
E0L14_RS00555	COG1629	transport
E0L14_RS00570	COG0302	gtp cyclohydrolase
E0L14_RS00580	COG0149	triose-phosphate isomerase activity
E0L14_RS00595	COG0739	heme binding
E0L14_RS00600	COG0105	UTP biosynthetic process
E0L14_RS00605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E0L14_RS00610	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E0L14_RS00630	COG0811	peptide transport
E0L14_RS00640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
E0L14_RS00705	COG1629	transport
E0L14_RS00740	COG0039	L-malate dehydrogenase activity
E0L14_RS00775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS00790	COG4948	Mandelate Racemase Muconate Lactonizing
E0L14_RS00810	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E0L14_RS00815	COG3118	belongs to the thioredoxin family
E0L14_RS00820	COG0489	protein tyrosine kinase activity
E0L14_RS00825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E0L14_RS00835	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E0L14_RS00840	COG1722	exodeoxyribonuclease VII activity
E0L14_RS00845	COG1570	exodeoxyribonuclease VII activity
E0L14_RS00855	COG0482	sulfurtransferase activity
E0L14_RS00875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
E0L14_RS00880	COG0179	Fumarylacetoacetate (FAA) hydrolase
E0L14_RS00885	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
E0L14_RS00895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E0L14_RS00900	COG0052	Belongs to the universal ribosomal protein uS2 family
E0L14_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E0L14_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E0L14_RS00925	COG0017	Asparaginyl-tRNA synthetase
E0L14_RS00930	COG1187	pseudouridine synthase activity
E0L14_RS00960	COG0110	maltose O-acetyltransferase activity
E0L14_RS00965	COG3022	response to hydroperoxide
E0L14_RS00970	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS01030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E0L14_RS01070	COG1442	glycosyl transferase family 8
E0L14_RS01070	COG1216	Glycosyl transferase, family 2
E0L14_RS01095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E0L14_RS01125	COG0297	glycogen (starch) synthase activity
E0L14_RS01270	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E0L14_RS01270	COG1918	ferrous iron import across plasma membrane
E0L14_RS01275	COG3507	Belongs to the glycosyl hydrolase 43 family
E0L14_RS01275	COG3693	PFAM glycoside hydrolase, family 10
E0L14_RS01275	COG2382	esterase
E0L14_RS01280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E0L14_RS01285	COG0436	Aminotransferase
E0L14_RS01290	COG0546	phosphoglycolate phosphatase activity
E0L14_RS01295	COG0351	phosphomethylpyrimidine kinase
E0L14_RS01300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0L14_RS01305	COG2217	Heavy metal translocating P-type atpase
E0L14_RS01320	COG1475	DNA binding
E0L14_RS01405	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
E0L14_RS01420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E0L14_RS01435	COG0516	GMP reductase activity
E0L14_RS01435	COG0517	IMP dehydrogenase activity
E0L14_RS01440	COG0514	ATP-dependent DNA helicase (RecQ)
E0L14_RS01445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
E0L14_RS01470	COG0724	RNA recognition motif
E0L14_RS01480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
E0L14_RS01485	COG1127	ABC transporter
E0L14_RS01490	COG2197	response regulator
E0L14_RS01495	COG1160	GTP binding
E0L14_RS01500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E0L14_RS01505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E0L14_RS01560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E0L14_RS01565	COG0470	DNA polymerase III
E0L14_RS01570	COG1774	PSP1 C-terminal conserved region
E0L14_RS01580	COG0772	Belongs to the SEDS family
E0L14_RS01595	COG1792	Involved in formation and maintenance of cell shape
E0L14_RS01605	COG0138	bifunctional purine biosynthesis protein purh
E0L14_RS01610	COG3590	peptidase
E0L14_RS01615	COG0488	(ABC) transporter
E0L14_RS01650	COG2205	protein histidine kinase activity
E0L14_RS01650	COG0784	Response regulator, receiver
E0L14_RS01655	COG0534	Mate efflux family protein
E0L14_RS01660	COG0612	Peptidase, M16
E0L14_RS01685	COG0564	pseudouridine synthase activity
E0L14_RS01730	COG2312	Erythromycin esterase
E0L14_RS01750	COG1131	(ABC) transporter
E0L14_RS01835	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
E0L14_RS01850	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
E0L14_RS01870	COG1696	Membrane protein involved in D-alanine export
E0L14_RS01910	COG2986	histidine ammonia-lyase
E0L14_RS01920	COG1228	amidohydrolase
E0L14_RS01930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E0L14_RS01960	COG0203	ribosomal protein L17
E0L14_RS01965	COG0202	RNA polymerase activity
E0L14_RS01970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E0L14_RS01975	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E0L14_RS01980	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E0L14_RS01985	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E0L14_RS01990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
E0L14_RS02005	COG0200	Binds to the 23S rRNA
E0L14_RS02010	COG1841	ribosomal large subunit assembly
E0L14_RS02015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
E0L14_RS02020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E0L14_RS02025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
E0L14_RS02030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E0L14_RS02035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
E0L14_RS02040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E0L14_RS02045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E0L14_RS02050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
E0L14_RS02055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
E0L14_RS02060	COG0255	Belongs to the universal ribosomal protein uL29 family
E0L14_RS02065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
E0L14_RS02070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
E0L14_RS02075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E0L14_RS02080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E0L14_RS02085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E0L14_RS02090	COG0089	rRNA binding
E0L14_RS02095	COG0088	Forms part of the polypeptide exit tunnel
E0L14_RS02100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E0L14_RS02105	COG0051	transcription antitermination factor activity, RNA binding
E0L14_RS02110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E0L14_RS02115	COG0049	tRNA binding
E0L14_RS02120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E0L14_RS02150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E0L14_RS02155	COG0085	RNA polymerase activity
E0L14_RS02160	COG0222	ribosome binding
E0L14_RS02165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E0L14_RS02170	COG0081	regulation of translation
E0L14_RS02175	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
E0L14_RS02220	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
E0L14_RS02225	COG4974	Belongs to the 'phage' integrase family
E0L14_RS02230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E0L14_RS02240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E0L14_RS02255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E0L14_RS02260	COG1480	7TM receptor with intracellular HD hydrolase
E0L14_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E0L14_RS02275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E0L14_RS02290	COG1027	Aspartate ammonia-lyase
E0L14_RS02295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E0L14_RS02300	COG0252	asparaginase activity
E0L14_RS02340	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
E0L14_RS02405	COG2271	Major facilitator Superfamily
E0L14_RS02415	COG4771	TonB-dependent receptor
E0L14_RS02420	COG0702	epimerase
E0L14_RS02430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS02450	COG4771	TonB-dependent receptor
E0L14_RS02520	COG1484	DNA-dependent DNA replication
E0L14_RS02575	COG2096	Adenosyltransferase
E0L14_RS02630	COG0657	acetylesterase activity
E0L14_RS02630	COG2755	lipolytic protein G-D-S-L family
E0L14_RS02680	COG3279	Response regulator of the LytR AlgR family
E0L14_RS02695	COG4206	TonB-dependent receptor
E0L14_RS02715	COG2197	response regulator
E0L14_RS02735	COG0662	Cupin 2, conserved barrel domain protein
E0L14_RS02735	COG2207	Transcriptional regulator
E0L14_RS02740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E0L14_RS02785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E0L14_RS02810	COG4974	Belongs to the 'phage' integrase family
E0L14_RS02840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E0L14_RS02850	COG1185	polyribonucleotide nucleotidyltransferase activity
E0L14_RS02865	COG4771	TonB-dependent receptor
E0L14_RS02900	COG3426	butyrate kinase activity
E0L14_RS02905	COG0280	phosphate acetyltransferase
E0L14_RS02915	COG1619	proteins homologs of microcin C7 resistance protein MccF
E0L14_RS02920	COG2234	aminopeptidase activity
E0L14_RS02925	COG2166	iron-sulfur cluster assembly
E0L14_RS02930	COG3655	Transcriptional regulator
E0L14_RS02940	COG1266	CAAX protease self-immunity
E0L14_RS02950	COG0196	riboflavin kinase activity
E0L14_RS02955	COG1011	Hydrolase
E0L14_RS02960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E0L14_RS02965	COG2205	protein histidine kinase activity
E0L14_RS02965	COG0784	Response regulator, receiver
E0L14_RS02970	COG1773	rubredoxin
E0L14_RS02975	COG1283	sodium-dependent phosphate transmembrane transporter activity
E0L14_RS02985	COG2205	protein histidine kinase activity
E0L14_RS03020	COG0006	proline dipeptidase activity
E0L14_RS03040	COG0509	glycine decarboxylation via glycine cleavage system
E0L14_RS03045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E0L14_RS03050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E0L14_RS03070	COG0702	epimerase
E0L14_RS03075	COG4771	TonB-dependent receptor
E0L14_RS03095	COG0793	Belongs to the peptidase S41A family
E0L14_RS03100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E0L14_RS03135	COG4771	TonB-dependent receptor
E0L14_RS03140	COG2205	protein histidine kinase activity
E0L14_RS03140	COG0745	RESPONSE REGULATOR receiver
E0L14_RS03140	COG3292	Two component regulator propeller
E0L14_RS03145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E0L14_RS03150	COG1882	Formate acetyltransferase
E0L14_RS03155	COG2814	Major facilitator Superfamily
E0L14_RS03155	COG0477	Major facilitator Superfamily
E0L14_RS03175	COG1040	competence protein
E0L14_RS03180	COG0483	inositol monophosphate 1-phosphatase activity
E0L14_RS03190	COG3345	alpha-galactosidase
E0L14_RS03215	COG3475	LICD family
E0L14_RS03220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E0L14_RS03250	COG1442	glycosyl transferase family 8
E0L14_RS03340	COG0018	arginyl-trna synthetase
E0L14_RS03370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E0L14_RS03375	COG0776	regulation of translation
E0L14_RS03415	COG2207	Transcriptional regulator
E0L14_RS03415	COG1609	Transcriptional regulator
E0L14_RS03435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E0L14_RS03435	COG0674	pyruvate-flavodoxin oxidoreductase activity
E0L14_RS03440	COG1013	pyruvate-flavodoxin oxidoreductase activity
E0L14_RS03455	COG0584	glycerophosphoryl diester phosphodiesterase
E0L14_RS03460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
E0L14_RS03465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
E0L14_RS03475	COG1629	transport
E0L14_RS03490	COG1629	transport
E0L14_RS03505	COG5434	Belongs to the glycosyl hydrolase 28 family
E0L14_RS03535	COG1629	transport
E0L14_RS03550	COG1217	gtp-binding protein TYPA
E0L14_RS03555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
E0L14_RS03565	COG0318	PFAM AMP-dependent synthetase and ligase
E0L14_RS03570	COG2205	protein histidine kinase activity
E0L14_RS03570	COG4999	Histidine kinase
E0L14_RS03570	COG3850	Histidine kinase
E0L14_RS03570	COG3437	response regulator, receiver
E0L14_RS03595	COG3119	arylsulfatase activity
E0L14_RS03625	COG4591	ABC-type transport system involved in lipoprotein release permease component
E0L14_RS03630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E0L14_RS03650	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E0L14_RS03655	COG4974	Belongs to the 'phage' integrase family
E0L14_RS03665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS03670	COG0606	chelatase, subunit chli
E0L14_RS03690	COG3292	Two component regulator propeller
E0L14_RS03690	COG0745	RESPONSE REGULATOR receiver
E0L14_RS03690	COG2205	protein histidine kinase activity
E0L14_RS03750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E0L14_RS03750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E0L14_RS03760	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS03785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E0L14_RS03790	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS03800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
E0L14_RS03805	COG0545	Peptidyl-prolyl cis-trans isomerase
E0L14_RS03810	COG0545	Peptidyl-prolyl cis-trans isomerase
E0L14_RS03815	COG1522	sequence-specific DNA binding
E0L14_RS03835	COG3275	phosphorelay sensor kinase activity
E0L14_RS03915	COG4206	TonB-dependent receptor
E0L14_RS03915	COG1629	transport
E0L14_RS03925	COG2814	Major facilitator Superfamily
E0L14_RS03930	COG3292	Two component regulator propeller
E0L14_RS03930	COG2205	protein histidine kinase activity
E0L14_RS03930	COG0745	RESPONSE REGULATOR receiver
E0L14_RS03935	COG1621	beta-fructofuranosidase activity
E0L14_RS03975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E0L14_RS03980	COG0793	Belongs to the peptidase S41A family
E0L14_RS03980	COG3409	Peptidoglycan-binding domain 1 protein
E0L14_RS04000	COG1053	succinate dehydrogenase
E0L14_RS04005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E0L14_RS04020	COG4771	TonB-dependent receptor
E0L14_RS04050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E0L14_RS04050	COG0758	DNA mediated transformation
E0L14_RS04060	COG0826	peptidase U32
E0L14_RS04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E0L14_RS04085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E0L14_RS04090	COG0557	exoribonuclease II activity
E0L14_RS04120	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E0L14_RS04135	COG0012	GTP binding
E0L14_RS04140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E0L14_RS04145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E0L14_RS04155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E0L14_RS04170	COG0495	leucyl-tRNA aminoacylation
E0L14_RS04175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E0L14_RS04190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E0L14_RS04210	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS04260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E0L14_RS04260	COG0731	radical SAM domain protein
E0L14_RS04285	COG0659	secondary active sulfate transmembrane transporter activity
E0L14_RS04290	COG1592	Rubrerythrin
E0L14_RS04295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
E0L14_RS04315	COG0427	acetyl-CoA hydrolase
E0L14_RS04325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E0L14_RS04335	COG3250	beta-galactosidase activity
E0L14_RS04505	COG2177	Part of the ABC transporter FtsEX involved in
E0L14_RS04515	COG1968	undecaprenyl-diphosphatase activity
E0L14_RS04520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
E0L14_RS04525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E0L14_RS04530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E0L14_RS04540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E0L14_RS04545	COG1611	Belongs to the LOG family
E0L14_RS04560	COG0594	ribonuclease P activity
E0L14_RS04565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
E0L14_RS04575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
E0L14_RS04580	COG1506	peptidase
E0L14_RS04580	COG4946	Tricorn protease homolog
E0L14_RS04580	COG0823	Involved in the tonB-independent uptake of proteins
E0L14_RS04590	COG3119	arylsulfatase activity
E0L14_RS04595	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
E0L14_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS04610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
E0L14_RS04650	COG1121	(ABC) transporter
E0L14_RS04660	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
E0L14_RS04660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E0L14_RS04675	COG0151	Belongs to the GarS family
E0L14_RS04680	COG0823	Involved in the tonB-independent uptake of proteins
E0L14_RS04680	COG1506	peptidase
E0L14_RS04685	COG0116	Belongs to the methyltransferase superfamily
E0L14_RS04690	COG1045	serine acetyltransferase
E0L14_RS04695	COG3275	phosphorelay sensor kinase activity
E0L14_RS04700	COG3279	Response regulator of the LytR AlgR family
E0L14_RS04710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E0L14_RS04710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E0L14_RS04730	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E0L14_RS04735	COG1694	Mazg nucleotide pyrophosphohydrolase
E0L14_RS04740	COG1490	D-aminoacyl-tRNA deacylase activity
E0L14_RS04745	COG0322	excinuclease ABC activity
E0L14_RS04750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E0L14_RS04755	COG0445	tRNA wobble uridine modification
E0L14_RS04785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E0L14_RS04820	COG2715	membrane protein required for spore maturation
E0L14_RS04830	COG2255	four-way junction helicase activity
E0L14_RS04845	COG3591	Belongs to the peptidase S1B family
E0L14_RS04860	COG0513	Belongs to the DEAD box helicase family
E0L14_RS04870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E0L14_RS04885	COG0612	Peptidase, M16
E0L14_RS04900	COG1312	Catalyzes the dehydration of D-mannonate
E0L14_RS04905	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS04915	COG0681	Belongs to the peptidase S26 family
E0L14_RS04920	COG0681	Belongs to the peptidase S26 family
E0L14_RS04925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E0L14_RS04955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E0L14_RS04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS04975	COG3250	beta-galactosidase activity
E0L14_RS04995	COG0215	cysteine-tRNA ligase activity
E0L14_RS05005	COG0561	phosphatase activity
E0L14_RS05010	COG0745	RESPONSE REGULATOR receiver
E0L14_RS05030	COG0745	RESPONSE REGULATOR receiver
E0L14_RS05035	COG5002	protein histidine kinase activity
E0L14_RS05040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
E0L14_RS05055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E0L14_RS05060	COG0482	sulfurtransferase activity
E0L14_RS05070	COG0205	6-phosphofructokinase activity
E0L14_RS05075	COG0571	ribonuclease III activity
E0L14_RS05080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E0L14_RS05085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E0L14_RS05090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E0L14_RS05095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0L14_RS05110	COG1442	glycosyl transferase family 8
E0L14_RS05120	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS05125	COG1442	glycosyl transferase family 8
E0L14_RS05125	COG1216	Glycosyl transferase, family 2
E0L14_RS05130	COG1132	(ABC) transporter
E0L14_RS05140	COG3341	Caulimovirus viroplasmin
E0L14_RS05140	COG0328	RNA-DNA hybrid ribonuclease activity
E0L14_RS05165	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E0L14_RS05175	COG0326	Molecular chaperone. Has ATPase activity
E0L14_RS05185	COG1166	arginine decarboxylase activity
E0L14_RS05190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E0L14_RS05255	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
E0L14_RS05260	COG1454	alcohol dehydrogenase
E0L14_RS05265	COG0235	Class ii aldolase
E0L14_RS05270	COG1070	Carbohydrate kinase
E0L14_RS05275	COG0738	Major facilitator superfamily
E0L14_RS05280	COG0779	Required for maturation of 30S ribosomal subunits
E0L14_RS05285	COG0195	Participates in both transcription termination and antitermination
E0L14_RS05290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
E0L14_RS05300	COG0719	Fe-S assembly protein
E0L14_RS05310	COG0396	ATPase activity
E0L14_RS05315	COG0719	Fe-S assembly protein
E0L14_RS05320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E0L14_RS05325	COG0393	Putative heavy-metal-binding
E0L14_RS05330	COG3345	alpha-galactosidase
E0L14_RS05340	COG1629	transport
E0L14_RS05365	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
E0L14_RS05375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E0L14_RS05385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
E0L14_RS05390	COG2205	protein histidine kinase activity
E0L14_RS05390	COG2202	Pas domain
E0L14_RS05410	COG0187	DNA topoisomerase II activity
E0L14_RS05415	COG0268	Binds directly to 16S ribosomal RNA
E0L14_RS05430	COG1381	Involved in DNA repair and RecF pathway recombination
E0L14_RS05435	COG1610	YqeY-like protein
E0L14_RS05440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E0L14_RS05455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E0L14_RS05460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
E0L14_RS05465	COG0772	Belongs to the SEDS family
E0L14_RS05470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E0L14_RS05475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS05480	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E0L14_RS05495	COG0275	rRNA processing
E0L14_RS05500	COG2001	Belongs to the MraZ family
E0L14_RS05520	COG4771	TonB-dependent receptor
E0L14_RS05550	COG0756	dUTP diphosphatase activity
E0L14_RS05565	COG4942	peptidase
E0L14_RS05570	COG0745	RESPONSE REGULATOR receiver
E0L14_RS05570	COG3292	Two component regulator propeller
E0L14_RS05570	COG2205	protein histidine kinase activity
E0L14_RS05575	COG3940	Belongs to the glycosyl hydrolase 43 family
E0L14_RS05590	COG3250	beta-galactosidase activity
E0L14_RS05605	COG3940	Belongs to the glycosyl hydrolase 43 family
E0L14_RS05625	COG0383	alpha-mannosidase activity
E0L14_RS05630	COG1629	transport
E0L14_RS05630	COG4206	TonB-dependent receptor
E0L14_RS05650	COG3507	Belongs to the glycosyl hydrolase 43 family
E0L14_RS05685	COG3537	Alpha-1,2-mannosidase
E0L14_RS05695	COG2017	converts alpha-aldose to the beta-anomer
E0L14_RS05785	COG3408	Glycogen debranching enzyme
E0L14_RS05790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E0L14_RS05795	COG1022	Amp-dependent synthetase and ligase
E0L14_RS05810	COG2954	triphosphatase activity
E0L14_RS05830	COG3250	beta-galactosidase activity
E0L14_RS05835	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS05845	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
E0L14_RS05865	COG4206	TonB-dependent receptor
E0L14_RS05865	COG1629	transport
E0L14_RS05870	COG3292	Two component regulator propeller
E0L14_RS05870	COG0745	RESPONSE REGULATOR receiver
E0L14_RS05870	COG2205	protein histidine kinase activity
E0L14_RS05875	COG0745	RESPONSE REGULATOR receiver
E0L14_RS05875	COG3292	Two component regulator propeller
E0L14_RS05875	COG2205	protein histidine kinase activity
E0L14_RS05900	COG4771	TonB-dependent receptor
E0L14_RS05920	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
E0L14_RS05970	COG4771	TonB-dependent receptor
E0L14_RS05995	COG0423	glycine-tRNA ligase activity
E0L14_RS06000	COG0545	Peptidyl-prolyl cis-trans isomerase
E0L14_RS06030	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
E0L14_RS06040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E0L14_RS06060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E0L14_RS06080	COG3876	Protein conserved in bacteria
E0L14_RS06115	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E0L14_RS06120	COG3876	Protein conserved in bacteria
E0L14_RS06125	COG0702	epimerase
E0L14_RS06130	COG1629	transport
E0L14_RS06130	COG4206	TonB-dependent receptor
E0L14_RS06150	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E0L14_RS06155	COG0589	response to stress
E0L14_RS06155	COG0475	glutathione-regulated potassium exporter activity
E0L14_RS06160	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E0L14_RS06165	COG1136	(ABC) transporter
E0L14_RS06175	COG0733	neurotransmitter:sodium symporter activity
E0L14_RS06185	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E0L14_RS06200	COG0076	glutamate decarboxylase activity
E0L14_RS06205	COG2066	Belongs to the glutaminase family
E0L14_RS06210	COG0784	Response regulator, receiver
E0L14_RS06210	COG5002	protein histidine kinase activity
E0L14_RS06210	COG2198	Histidine kinase
E0L14_RS06215	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E0L14_RS06220	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E0L14_RS06315	COG1346	cytolysis
E0L14_RS06340	COG0280	phosphate acetyltransferase
E0L14_RS06345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E0L14_RS06350	COG1785	Belongs to the alkaline phosphatase family
E0L14_RS06355	COG2151	metal-sulfur cluster biosynthetic enzyme
E0L14_RS06360	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E0L14_RS06365	COG2003	Belongs to the UPF0758 family
E0L14_RS06370	COG1216	Glycosyl transferase, family 2
E0L14_RS06370	COG0463	Glycosyl transferase, family 2
E0L14_RS06385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E0L14_RS06390	COG2815	serine threonine protein kinase
E0L14_RS06390	COG0515	serine threonine protein kinase
E0L14_RS06395	COG0564	pseudouridine synthase activity
E0L14_RS06400	COG1181	Belongs to the D-alanine--D-alanine ligase family
E0L14_RS06440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
E0L14_RS06445	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
E0L14_RS06455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E0L14_RS06475	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
E0L14_RS06485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E0L14_RS06485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E0L14_RS06490	COG2890	protein-(glutamine-N5) methyltransferase activity
E0L14_RS06495	COG2137	regulation of response to DNA damage stimulus
E0L14_RS06500	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
E0L14_RS06510	COG0165	Argininosuccinate lyase
E0L14_RS06595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E0L14_RS06600	COG1917	Cupin 2, conserved barrel domain protein
E0L14_RS06600	COG1396	sequence-specific DNA binding
E0L14_RS06605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E0L14_RS06610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E0L14_RS06615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E0L14_RS06620	COG0137	argininosuccinate synthase activity
E0L14_RS06630	COG1438	arginine binding
E0L14_RS06645	COG0784	Response regulator, receiver
E0L14_RS06645	COG2205	protein histidine kinase activity
E0L14_RS06650	COG0531	amino acid
E0L14_RS06660	COG0039	L-malate dehydrogenase activity
E0L14_RS06665	COG2996	Protein conserved in bacteria
E0L14_RS06685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E0L14_RS06690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E0L14_RS06715	COG1629	transport
E0L14_RS06745	COG1136	(ABC) transporter
E0L14_RS06745	COG0577	efflux transmembrane transporter activity
E0L14_RS06750	COG1136	(ABC) transporter
E0L14_RS06750	COG0577	efflux transmembrane transporter activity
E0L14_RS06755	COG1136	(ABC) transporter
E0L14_RS06760	COG1940	carbohydrate kinase activity
E0L14_RS06765	COG0335	large ribosomal subunit rRNA binding
E0L14_RS06770	COG0737	Belongs to the 5'-nucleotidase family
E0L14_RS06775	COG0737	Belongs to the 5'-nucleotidase family
E0L14_RS06780	COG1472	Belongs to the glycosyl hydrolase 3 family
E0L14_RS06785	COG1472	Belongs to the glycosyl hydrolase 3 family
E0L14_RS06790	COG4206	TonB-dependent receptor
E0L14_RS06790	COG1629	transport
E0L14_RS06800	COG3119	arylsulfatase activity
E0L14_RS06825	COG0446	pyridine nucleotide-disulphide oxidoreductase
E0L14_RS06835	COG2204	response regulator
E0L14_RS06845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
E0L14_RS06855	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E0L14_RS06865	COG2205	protein histidine kinase activity
E0L14_RS06870	COG5002	protein histidine kinase activity
E0L14_RS06885	COG4771	TonB-dependent receptor
E0L14_RS06930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E0L14_RS06930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E0L14_RS06935	COG0436	Aminotransferase
E0L14_RS06940	COG3250	beta-galactosidase activity
E0L14_RS06950	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
E0L14_RS06955	COG0826	peptidase U32
E0L14_RS06965	COG4771	TonB-dependent receptor
E0L14_RS06970	COG2197	response regulator
E0L14_RS06975	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
E0L14_RS06985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E0L14_RS06995	COG0252	asparaginase activity
E0L14_RS07000	COG0527	aspartate kinase activity
E0L14_RS07000	COG0460	homoserine dehydrogenase
E0L14_RS07005	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
E0L14_RS07010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
E0L14_RS07070	COG1629	transport
E0L14_RS07070	COG4206	TonB-dependent receptor
E0L14_RS07075	COG0702	epimerase
E0L14_RS07080	COG3250	beta-galactosidase activity
E0L14_RS07090	COG3507	Belongs to the glycosyl hydrolase 43 family
E0L14_RS07105	COG4771	TonB-dependent receptor
E0L14_RS07130	COG0628	permease
E0L14_RS07135	COG1435	thymidine kinase activity
E0L14_RS07145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E0L14_RS07160	COG2095	MarC family integral membrane protein
E0L14_RS07170	COG1629	transport
E0L14_RS07180	COG1629	transport
E0L14_RS07185	COG4974	Belongs to the 'phage' integrase family
E0L14_RS07195	COG4206	TonB-dependent receptor
E0L14_RS07195	COG1629	transport
E0L14_RS07205	COG4771	TonB-dependent receptor
E0L14_RS07210	COG0702	epimerase
E0L14_RS07215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E0L14_RS07235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
E0L14_RS07235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
E0L14_RS07250	COG0531	amino acid
E0L14_RS07265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E0L14_RS07270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS07275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS07315	COG1162	GTPase activity
E0L14_RS07320	COG0233	cytoplasmic translational termination
E0L14_RS07340	COG0443	Heat shock 70 kDa protein
E0L14_RS07360	COG0528	UMP kinase activity
E0L14_RS07365	COG0534	Mate efflux family protein
E0L14_RS07400	COG0792	nuclease activity
E0L14_RS07425	COG1183	phosphatidylcholine synthase activity
E0L14_RS07430	COG0688	phosphatidylethanolamine metabolic process
E0L14_RS07440	COG3118	belongs to the thioredoxin family
E0L14_RS07480	COG0714	Associated with various cellular activities
E0L14_RS07495	COG0802	atpase or kinase
E0L14_RS07500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E0L14_RS07510	COG2234	aminopeptidase activity
E0L14_RS07535	COG1629	transport
E0L14_RS07555	COG3250	beta-galactosidase activity
E0L14_RS07560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E0L14_RS07570	COG2205	protein histidine kinase activity
E0L14_RS07570	COG0784	Response regulator, receiver
E0L14_RS07595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E0L14_RS07610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E0L14_RS07615	COG0742	ribosomal rna small subunit methyltransferase
E0L14_RS07640	COG4771	TonB-dependent receptor
E0L14_RS07650	COG3537	Alpha-1,2-mannosidase
E0L14_RS07665	COG3537	Alpha-1,2-mannosidase
E0L14_RS07675	COG2814	Major facilitator Superfamily
E0L14_RS07685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E0L14_RS07690	COG0739	heme binding
E0L14_RS07700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E0L14_RS07705	COG3942	CHAP domain
E0L14_RS07705	COG1388	LysM domain
E0L14_RS07715	COG1475	DNA binding
E0L14_RS07720	COG1192	Involved in chromosome partitioning
E0L14_RS07730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
E0L14_RS07735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E0L14_RS07745	COG4589	Belongs to the CDS family
E0L14_RS07750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E0L14_RS07755	COG0799	negative regulation of ribosome biogenesis
E0L14_RS07770	COG2239	Acts as a magnesium transporter
E0L14_RS07775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E0L14_RS07785	COG2195	Cleaves the N-terminal amino acid of tripeptides
E0L14_RS07865	COG0668	transmembrane transport
E0L14_RS07870	COG0662	Cupin 2, conserved barrel domain protein
E0L14_RS07870	COG2207	Transcriptional regulator
E0L14_RS07920	COG1086	Polysaccharide biosynthesis protein
E0L14_RS07925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E0L14_RS07935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E0L14_RS07970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E0L14_RS07975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E0L14_RS07995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E0L14_RS08010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E0L14_RS08035	COG0667	Aldo Keto reductase
E0L14_RS08040	COG1472	Belongs to the glycosyl hydrolase 3 family
E0L14_RS08045	COG4771	TonB-dependent receptor
E0L14_RS08050	COG0702	epimerase
E0L14_RS08095	COG5012	cobalamin binding
E0L14_RS08110	COG4124	Belongs to the glycosyl hydrolase 26 family
E0L14_RS08115	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
E0L14_RS08120	COG2211	Major facilitator Superfamily
E0L14_RS08125	COG2942	2-epimerase
E0L14_RS08175	COG2205	protein histidine kinase activity
E0L14_RS08175	COG2202	Pas domain
E0L14_RS08185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0L14_RS08190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E0L14_RS08195	COG0713	ATP synthesis coupled electron transport
E0L14_RS08200	COG0839	Belongs to the complex I subunit 6 family
E0L14_RS08210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E0L14_RS08215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0L14_RS08215	COG0649	NAD binding
E0L14_RS08220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0L14_RS08225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E0L14_RS08235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E0L14_RS08240	COG0569	domain protein
E0L14_RS08245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
E0L14_RS08255	COG1073	alpha beta
E0L14_RS08270	COG3119	arylsulfatase activity
E0L14_RS08285	COG3119	arylsulfatase activity
E0L14_RS08295	COG4771	TonB-dependent receptor
E0L14_RS08300	COG0745	RESPONSE REGULATOR receiver
E0L14_RS08300	COG3292	Two component regulator propeller
E0L14_RS08300	COG2205	protein histidine kinase activity
E0L14_RS08305	COG2271	Major facilitator Superfamily
E0L14_RS08330	COG0805	protein transport
E0L14_RS08335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E0L14_RS08340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E0L14_RS08395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E0L14_RS08405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E0L14_RS08410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E0L14_RS08410	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
E0L14_RS08415	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
E0L14_RS08420	COG1078	dGTPase activity
E0L14_RS08425	COG0284	orotidine-5'-phosphate decarboxylase activity
E0L14_RS08430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E0L14_RS08435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E0L14_RS08450	COG1704	LemA family
E0L14_RS08465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E0L14_RS08470	COG2226	methyltransferase
E0L14_RS08475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E0L14_RS08480	COG1702	phosphate starvation-inducible protein PhoH
E0L14_RS08490	COG2268	Band 7 protein
E0L14_RS08500	COG5434	Belongs to the glycosyl hydrolase 28 family
E0L14_RS08510	COG0101	tRNA pseudouridine synthase activity
E0L14_RS08530	COG3250	beta-galactosidase activity
E0L14_RS08535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E0L14_RS08560	COG0457	Tetratricopeptide repeat
E0L14_RS08565	COG2814	Major facilitator Superfamily
E0L14_RS08590	COG0561	phosphatase activity
E0L14_RS08595	COG1629	transport
E0L14_RS08595	COG4206	TonB-dependent receptor
E0L14_RS08605	COG4771	TonB-dependent receptor
E0L14_RS08615	COG4206	TonB-dependent receptor
E0L14_RS08615	COG1629	transport
E0L14_RS08635	COG1629	transport
E0L14_RS08635	COG4206	TonB-dependent receptor
E0L14_RS08640	COG0702	epimerase
E0L14_RS08650	COG0673	inositol 2-dehydrogenase activity
E0L14_RS08675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E0L14_RS08695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E0L14_RS08700	COG0793	Belongs to the peptidase S41A family
E0L14_RS08705	COG2131	deaminase
E0L14_RS08715	COG0339	signal peptide processing
E0L14_RS08725	COG1970	mechanosensitive ion channel activity
E0L14_RS08730	COG0519	Catalyzes the synthesis of GMP from XMP
E0L14_RS08730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E0L14_RS08740	COG1629	transport
E0L14_RS08740	COG4206	TonB-dependent receptor
E0L14_RS08750	COG1629	transport
E0L14_RS08750	COG4206	TonB-dependent receptor
E0L14_RS08755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E0L14_RS08775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E0L14_RS08805	COG1242	4 iron, 4 sulfur cluster binding
E0L14_RS08815	COG0363	glucosamine-6-phosphate deaminase activity
E0L14_RS08825	COG0009	L-threonylcarbamoyladenylate synthase
E0L14_RS08835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E0L14_RS08840	COG0561	phosphatase activity
E0L14_RS08845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E0L14_RS08850	COG2873	o-acetylhomoserine
E0L14_RS08905	COG0297	glycogen (starch) synthase activity
E0L14_RS08910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
E0L14_RS08915	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
E0L14_RS08920	COG0543	2 iron, 2 sulfur cluster binding
E0L14_RS08930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
E0L14_RS08940	COG0211	Belongs to the bacterial ribosomal protein bL27 family
E0L14_RS08945	COG0261	This protein binds to 23S rRNA in the presence of protein L20
E0L14_RS08965	COG0546	phosphoglycolate phosphatase activity
E0L14_RS08970	COG0791	NLP P60 protein
E0L14_RS08985	COG0612	Peptidase, M16
E0L14_RS08990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
E0L14_RS08995	COG1597	lipid kinase activity
E0L14_RS09000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E0L14_RS09010	COG1136	(ABC) transporter
E0L14_RS09030	COG2211	Major facilitator Superfamily
E0L14_RS09045	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E0L14_RS09060	COG1674	ftsk spoiiie
E0L14_RS09070	COG0492	ferredoxin-NADP+ reductase activity
E0L14_RS09075	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS09115	COG1234	tRNA 3'-trailer cleavage
E0L14_RS09120	COG1595	DNA-templated transcription, initiation
E0L14_RS09135	COG3956	TIGRFAM MazG family protein
E0L14_RS09145	COG0525	valine-tRNA ligase activity
E0L14_RS09150	COG0784	Response regulator, receiver
E0L14_RS09150	COG2198	Histidine kinase
E0L14_RS09150	COG2205	protein histidine kinase activity
E0L14_RS09175	COG4771	TonB-dependent receptor
E0L14_RS09190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
E0L14_RS09205	COG4206	TonB-dependent receptor
E0L14_RS09205	COG1629	transport
E0L14_RS09210	COG0702	epimerase
E0L14_RS09215	COG3119	arylsulfatase activity
E0L14_RS09220	COG3119	arylsulfatase activity
E0L14_RS09235	COG0653	protein targeting
E0L14_RS09240	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
E0L14_RS09255	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
E0L14_RS09275	COG1253	flavin adenine dinucleotide binding
E0L14_RS09285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E0L14_RS09295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
E0L14_RS09335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
E0L14_RS09345	COG2226	methyltransferase
E0L14_RS09395	COG0110	maltose O-acetyltransferase activity
E0L14_RS09410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
E0L14_RS09430	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS09435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS09440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS09455	COG4771	TonB-dependent receptor
E0L14_RS09465	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E0L14_RS09470	COG0563	adenylate kinase activity
E0L14_RS09475	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E0L14_RS09480	COG1496	oxidoreductase activity
E0L14_RS09500	COG2706	6-phosphogluconolactonase activity
E0L14_RS09540	COG1288	antiporter activity
E0L14_RS09560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E0L14_RS09580	COG0564	pseudouridine synthase activity
E0L14_RS09595	COG1501	Belongs to the glycosyl hydrolase 31 family
E0L14_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS09670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E0L14_RS09750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E0L14_RS09845	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E0L14_RS09845	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E0L14_RS09890	COG4974	Belongs to the 'phage' integrase family
E0L14_RS09900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E0L14_RS09905	COG2205	protein histidine kinase activity
E0L14_RS09905	COG0784	Response regulator, receiver
E0L14_RS09910	COG2910	NAD(P)H-binding
E0L14_RS09915	COG2176	DNA-directed DNA polymerase activity
E0L14_RS09925	COG4864	UPF0365 protein
E0L14_RS09940	COG0037	tRNA processing
E0L14_RS09960	COG1477	protein flavinylation
E0L14_RS09965	COG1971	Probably functions as a manganese efflux pump
E0L14_RS09980	COG0463	Glycosyl transferase, family 2
E0L14_RS09995	COG0148	phosphopyruvate hydratase activity
E0L14_RS10005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
E0L14_RS10010	COG1082	Xylose isomerase domain protein TIM barrel
E0L14_RS10035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E0L14_RS10040	COG0193	aminoacyl-tRNA hydrolase activity
E0L14_RS10045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
E0L14_RS10055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E0L14_RS10060	COG1862	Preprotein translocase
E0L14_RS10070	COG0237	dephospho-CoA kinase activity
E0L14_RS10085	COG0542	response to heat
E0L14_RS10095	COG0583	DNA-binding transcription factor activity
E0L14_RS10100	COG2855	membrane
E0L14_RS10115	COG1595	DNA-templated transcription, initiation
E0L14_RS10130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0L14_RS10150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E0L14_RS10175	COG0443	Heat shock 70 kDa protein
E0L14_RS10185	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
E0L14_RS10190	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
E0L14_RS10195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E0L14_RS10215	COG1501	Belongs to the glycosyl hydrolase 31 family
E0L14_RS10245	COG4206	TonB-dependent receptor
E0L14_RS10245	COG1629	transport
E0L14_RS10255	COG1408	metallophosphoesterase
E0L14_RS10260	COG1368	sulfuric ester hydrolase activity
E0L14_RS10270	COG3634	alkyl hydroperoxide reductase activity
E0L14_RS10310	COG1760	l-serine dehydratase
E0L14_RS10315	COG0598	Magnesium transport protein CorA
E0L14_RS10320	COG1193	negative regulation of DNA recombination
E0L14_RS10330	COG4974	Belongs to the 'phage' integrase family
E0L14_RS10340	COG2003	Belongs to the UPF0758 family
E0L14_RS10515	COG0551	DNA topoisomerase type I activity
E0L14_RS10515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E0L14_RS10545	COG0534	Mate efflux family protein
E0L14_RS10575	COG0546	phosphoglycolate phosphatase activity
E0L14_RS10585	COG2207	Transcriptional regulator
E0L14_RS10620	COG1063	alcohol dehydrogenase
E0L14_RS10635	COG3119	arylsulfatase activity
E0L14_RS10640	COG5002	protein histidine kinase activity
E0L14_RS10645	COG2855	membrane
E0L14_RS10650	COG2217	Heavy metal translocating P-type atpase
E0L14_RS10660	COG2885	chlorophyll binding
E0L14_RS10670	COG3189	MarR family transcriptional regulator
E0L14_RS10675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E0L14_RS10680	COG2195	Cleaves the N-terminal amino acid of tripeptides
E0L14_RS10685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E0L14_RS10705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E0L14_RS10705	COG4651	solute:proton antiporter activity
E0L14_RS10710	COG1280	lysine exporter protein (LysE YggA)
E0L14_RS10725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
E0L14_RS10740	COG0561	phosphatase activity
E0L14_RS10745	COG1169	isochorismate synthase
E0L14_RS10750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
E0L14_RS10765	COG4948	Mandelate Racemase Muconate Lactonizing
E0L14_RS10780	COG1082	Xylose isomerase domain protein TIM barrel
E0L14_RS10795	COG4771	TonB-dependent receptor
E0L14_RS10825	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
E0L14_RS10830	COG0783	Belongs to the Dps family
E0L14_RS10835	COG0583	DNA-binding transcription factor activity
E0L14_RS10855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E0L14_RS10910	COG1253	flavin adenine dinucleotide binding
E0L14_RS10915	COG0501	Belongs to the peptidase M48B family
E0L14_RS10945	COG2873	o-acetylhomoserine
E0L14_RS10950	COG0482	sulfurtransferase activity
E0L14_RS10955	COG2197	response regulator
E0L14_RS10965	COG1757	Na H antiporter
E0L14_RS10980	COG2814	Major facilitator Superfamily
E0L14_RS10985	COG4953	penicillin-binding protein 1C
E0L14_RS10990	COG2373	Large extracellular alpha-helical protein
E0L14_RS11000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E0L14_RS11000	COG1918	ferrous iron import across plasma membrane
E0L14_RS11095	COG2244	polysaccharide biosynthetic process
E0L14_RS11100	COG0562	UDP-galactopyranose mutase
E0L14_RS11105	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS11120	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS11130	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E0L14_RS11135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E0L14_RS11145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS11150	COG0490	domain, Protein
E0L14_RS11150	COG0471	metal ion transport
E0L14_RS11165	COG0346	lactoylglutathione lyase activity
E0L14_RS11180	COG0259	pyridoxamine-phosphate oxidase activity
E0L14_RS11185	COG1741	Belongs to the pirin family
E0L14_RS11205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E0L14_RS11235	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E0L14_RS11240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E0L14_RS11245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E0L14_RS11260	COG1595	DNA-templated transcription, initiation
E0L14_RS11285	COG0686	Belongs to the AlaDH PNT family
E0L14_RS11300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E0L14_RS11320	COG1629	transport
E0L14_RS11335	COG3345	alpha-galactosidase
E0L14_RS11365	COG0488	(ABC) transporter
E0L14_RS11370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E0L14_RS11375	COG3059	membrane
E0L14_RS11380	COG1917	Cupin 2, conserved barrel domain protein
E0L14_RS11380	COG2207	Transcriptional regulator
E0L14_RS11385	COG0295	cytidine deaminase activity
E0L14_RS11390	COG1388	LysM domain
E0L14_RS11390	COG1705	Flagellar rod assembly protein muramidase FlgJ
E0L14_RS11405	COG0577	efflux transmembrane transporter activity
E0L14_RS11415	COG0577	efflux transmembrane transporter activity
E0L14_RS11425	COG1136	(ABC) transporter
E0L14_RS11425	COG0577	efflux transmembrane transporter activity
E0L14_RS11440	COG1136	(ABC) transporter
E0L14_RS11455	COG1136	(ABC) transporter
E0L14_RS11475	COG2205	protein histidine kinase activity
E0L14_RS11475	COG0784	Response regulator, receiver
E0L14_RS11700	COG0741	lytic transglycosylase activity
E0L14_RS11700	COG0739	heme binding
E0L14_RS11700	COG1196	nuclear chromosome segregation
E0L14_RS11730	COG1192	Involved in chromosome partitioning
E0L14_RS11740	COG3392	D12 class N6 adenine-specific DNA methyltransferase
E0L14_RS11765	COG0702	epimerase
E0L14_RS11770	COG4771	TonB-dependent receptor
E0L14_RS11900	COG4974	Belongs to the 'phage' integrase family
E0L14_RS11980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS11985	COG2244	polysaccharide biosynthetic process
E0L14_RS11990	COG1216	Glycosyl transferase, family 2
E0L14_RS11990	COG1442	glycosyl transferase family 8
E0L14_RS12015	COG0463	Glycosyl transferase, family 2
E0L14_RS12025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS12030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS12035	COG1530	ribonuclease E activity
E0L14_RS12050	COG3119	arylsulfatase activity
E0L14_RS12055	COG0629	single-stranded DNA binding
E0L14_RS12115	COG4206	TonB-dependent receptor
E0L14_RS12140	COG5002	protein histidine kinase activity
E0L14_RS12145	COG0745	RESPONSE REGULATOR receiver
E0L14_RS12175	COG0488	(ABC) transporter
E0L14_RS12190	COG5492	domain, Protein
E0L14_RS12200	COG0436	Aminotransferase
E0L14_RS12205	COG4591	ABC-type transport system involved in lipoprotein release permease component
E0L14_RS12210	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS12215	COG0628	permease
E0L14_RS12220	COG3852	Histidine kinase
E0L14_RS12235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS12245	COG0577	efflux transmembrane transporter activity
E0L14_RS12245	COG1136	(ABC) transporter
E0L14_RS12250	COG0577	efflux transmembrane transporter activity
E0L14_RS12255	COG1252	NADH dehydrogenase
E0L14_RS12275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E0L14_RS12275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E0L14_RS12285	COG4771	TonB-dependent receptor
E0L14_RS12295	COG1620	l-lactate permease
E0L14_RS12300	COG2885	chlorophyll binding
E0L14_RS12300	COG3047	cAMP biosynthetic process
E0L14_RS12310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E0L14_RS12315	COG0439	Biotin carboxylase
E0L14_RS12320	COG0511	ligase activity, forming carbon-carbon bonds
E0L14_RS12325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E0L14_RS12370	COG0508	dehydrogenase complex catalyzes the overall conversion of
E0L14_RS12375	COG0022	dehydrogenase e1 component
E0L14_RS12380	COG0716	FMN binding
E0L14_RS12385	COG2264	protein methyltransferase activity
E0L14_RS12435	COG0590	tRNA wobble adenosine to inosine editing
E0L14_RS12465	COG0673	inositol 2-dehydrogenase activity
E0L14_RS12475	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
E0L14_RS12515	COG0698	ribose 5-phosphate isomerase
E0L14_RS12520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
E0L14_RS12525	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
E0L14_RS12540	COG1482	cell wall glycoprotein biosynthetic process
E0L14_RS12560	COG0513	Belongs to the DEAD box helicase family
E0L14_RS12565	COG4221	oxidoreductase activity
E0L14_RS12580	COG3250	beta-galactosidase activity
E0L14_RS12590	COG3273	potassium ion transport
E0L14_RS12590	COG0471	metal ion transport
E0L14_RS12595	COG0529	Catalyzes the synthesis of activated sulfate
E0L14_RS12600	COG0175	sulfate reduction
E0L14_RS12605	COG2895	sulfate adenylyltransferase (ATP) activity
E0L14_RS12645	COG4974	Belongs to the 'phage' integrase family
E0L14_RS12670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E0L14_RS12675	COG0242	peptide deformylase activity
E0L14_RS12690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E0L14_RS12695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
E0L14_RS12700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
E0L14_RS12705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E0L14_RS12715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E0L14_RS12720	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E0L14_RS12735	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E0L14_RS12785	COG1940	carbohydrate kinase activity
E0L14_RS12790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0L14_RS12800	COG2271	Major facilitator Superfamily
E0L14_RS12805	COG2731	YhcH YjgK YiaL family protein
E0L14_RS12815	COG0702	epimerase
E0L14_RS12820	COG1629	transport
E0L14_RS12825	COG0702	epimerase
E0L14_RS12845	COG1629	transport
E0L14_RS12850	COG0702	epimerase
E0L14_RS12860	COG4974	Belongs to the 'phage' integrase family
E0L14_RS12885	COG1733	regulation of RNA biosynthetic process
E0L14_RS12940	COG1475	DNA binding
E0L14_RS12960	COG2003	Belongs to the UPF0758 family
E0L14_RS13175	COG4974	Belongs to the 'phage' integrase family
E0L14_RS13185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E0L14_RS13185	COG0551	DNA topoisomerase type I activity
E0L14_RS13265	COG4771	TonB-dependent receptor
E0L14_RS13270	COG0702	epimerase
E0L14_RS13275	COG0702	epimerase
E0L14_RS13280	COG4206	TonB-dependent receptor
E0L14_RS13280	COG1629	transport
E0L14_RS13285	COG1629	transport
E0L14_RS13285	COG4206	TonB-dependent receptor
E0L14_RS13305	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS13325	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS13335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS13340	COG3537	Alpha-1,2-mannosidase
E0L14_RS13345	COG3250	beta-galactosidase activity
E0L14_RS13350	COG4206	TonB-dependent receptor
E0L14_RS13350	COG1629	transport
E0L14_RS13355	COG0702	epimerase
E0L14_RS13365	COG0484	heat shock protein binding
E0L14_RS13370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E0L14_RS13375	COG0488	(ABC) transporter
E0L14_RS13380	COG1595	DNA-templated transcription, initiation
E0L14_RS13470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
E0L14_RS13500	COG0732	type I restriction modification DNA specificity domain
E0L14_RS13505	COG0582	viral genome integration into host DNA
E0L14_RS13530	COG2885	chlorophyll binding
E0L14_RS13645	COG2183	response to ionizing radiation
E0L14_RS13650	COG2205	protein histidine kinase activity
E0L14_RS13655	COG0737	Belongs to the 5'-nucleotidase family
E0L14_RS13660	COG1956	GAF domain-containing protein
E0L14_RS13670	COG4771	TonB-dependent receptor
E0L14_RS13695	COG0534	Mate efflux family protein
E0L14_RS13710	COG0534	Mate efflux family protein
E0L14_RS13720	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
E0L14_RS13730	COG0318	PFAM AMP-dependent synthetase and ligase
E0L14_RS13735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS13740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
E0L14_RS13780	COG4750	Nucleotidyl transferase
E0L14_RS13795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E0L14_RS13825	COG1216	Glycosyl transferase, family 2
E0L14_RS13830	COG1216	Glycosyl transferase, family 2
E0L14_RS13845	COG1086	Polysaccharide biosynthesis protein
E0L14_RS13855	COG1091	dTDP-4-dehydrorhamnose reductase activity
E0L14_RS13865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS13870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS13890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
E0L14_RS13895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
E0L14_RS13900	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E0L14_RS13905	COG0363	glucosamine-6-phosphate deaminase activity
E0L14_RS13925	COG4413	Urea transporter
E0L14_RS13955	COG3279	Response regulator of the LytR AlgR family
E0L14_RS13965	COG1136	(ABC) transporter
E0L14_RS13965	COG0577	efflux transmembrane transporter activity
E0L14_RS13970	COG1136	(ABC) transporter
E0L14_RS13975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS14000	COG4884	unkown
E0L14_RS14000	COG3831	ATPase activity
E0L14_RS14015	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E0L14_RS14025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E0L14_RS14030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E0L14_RS14035	COG3250	beta-galactosidase activity
E0L14_RS14065	COG0501	Belongs to the peptidase M48B family
E0L14_RS14070	COG1704	LemA family
E0L14_RS14075	COG1595	DNA-templated transcription, initiation
E0L14_RS14090	COG4206	TonB-dependent receptor
E0L14_RS14090	COG1629	transport
E0L14_RS14100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E0L14_RS14105	COG2885	chlorophyll binding
E0L14_RS14105	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E0L14_RS14115	COG0697	spore germination
E0L14_RS14145	COG0776	regulation of translation
E0L14_RS14205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E0L14_RS14225	COG1846	Transcriptional regulator
E0L14_RS14225	COG0456	acetyltransferase
E0L14_RS14230	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E0L14_RS14235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E0L14_RS14240	COG2814	Major facilitator Superfamily
E0L14_RS14245	COG4771	TonB-dependent receptor
E0L14_RS14285	COG4771	TonB-dependent receptor
E0L14_RS14440	COG0542	response to heat
E0L14_RS14470	COG0156	8-amino-7-oxononanoate synthase activity
E0L14_RS14565	COG0488	(ABC) transporter
E0L14_RS14585	COG2205	protein histidine kinase activity
E0L14_RS14585	COG2198	Histidine kinase
E0L14_RS14585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0L14_RS14585	COG0784	Response regulator, receiver
E0L14_RS14610	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS14625	COG2244	polysaccharide biosynthetic process
E0L14_RS14630	COG1216	Glycosyl transferase, family 2
E0L14_RS14630	COG1442	glycosyl transferase family 8
E0L14_RS14640	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS14670	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E0L14_RS14675	COG1805	sodium ion transport
E0L14_RS14680	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
E0L14_RS14705	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
E0L14_RS14710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E0L14_RS14720	COG0545	Peptidyl-prolyl cis-trans isomerase
E0L14_RS14725	COG1739	Uncharacterized protein family UPF0029
E0L14_RS14735	COG0778	Nitroreductase
E0L14_RS14740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E0L14_RS14740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E0L14_RS14745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E0L14_RS14775	COG2217	Heavy metal translocating P-type atpase
E0L14_RS14785	COG0321	lipoyl(octanoyl) transferase activity
E0L14_RS14820	COG3852	Histidine kinase
E0L14_RS14825	COG2204	response regulator
E0L14_RS14845	COG1136	(ABC) transporter
E0L14_RS14855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E0L14_RS14860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E0L14_RS14865	COG1755	Isoprenylcysteine carboxyl methyltransferase
E0L14_RS14880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
E0L14_RS14895	COG1678	Uncharacterized ACR, COG1678
E0L14_RS14970	COG0667	Aldo Keto reductase
E0L14_RS14995	COG0667	Aldo Keto reductase
E0L14_RS15005	COG0656	L-ascorbic acid biosynthetic process
E0L14_RS15015	COG0656	L-ascorbic acid biosynthetic process
E0L14_RS15035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E0L14_RS15050	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS15090	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS15095	COG0667	Aldo Keto reductase
E0L14_RS15110	COG2311	Membrane
E0L14_RS15115	COG0667	Aldo Keto reductase
E0L14_RS15205	COG4771	TonB-dependent receptor
E0L14_RS15240	COG1309	transcriptional regulator
E0L14_RS15255	COG1132	(ABC) transporter
E0L14_RS15265	COG2205	protein histidine kinase activity
E0L14_RS15280	COG1522	sequence-specific DNA binding
E0L14_RS15300	COG3969	phosphoadenosine phosphosulfate
E0L14_RS15305	COG1475	DNA binding
E0L14_RS15355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS15360	COG0745	RESPONSE REGULATOR receiver
E0L14_RS15375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS15385	COG4206	TonB-dependent receptor
E0L14_RS15385	COG1629	transport
E0L14_RS15395	COG2425	protein containing a von Willebrand factor type A (vWA) domain
E0L14_RS15415	COG1022	Amp-dependent synthetase and ligase
E0L14_RS15420	COG3263	regulation of cellular component size
E0L14_RS15430	COG1151	hydroxylamine reductase activity
E0L14_RS15465	COG0577	efflux transmembrane transporter activity
E0L14_RS15465	COG1136	(ABC) transporter
E0L14_RS15475	COG1136	(ABC) transporter
E0L14_RS15475	COG0577	efflux transmembrane transporter activity
E0L14_RS15490	COG0534	Mate efflux family protein
E0L14_RS15495	COG1011	Hydrolase
E0L14_RS15500	COG0167	dihydroorotate dehydrogenase activity
E0L14_RS15510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E0L14_RS15525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E0L14_RS15545	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
E0L14_RS15555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E0L14_RS15565	COG0356	it plays a direct role in the translocation of protons across the membrane
E0L14_RS15570	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E0L14_RS15575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E0L14_RS15580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E0L14_RS15585	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E0L14_RS15590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E0L14_RS15595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
E0L14_RS15600	COG3118	belongs to the thioredoxin family
E0L14_RS15620	COG0745	RESPONSE REGULATOR receiver
E0L14_RS15625	COG5002	protein histidine kinase activity
E0L14_RS15665	COG1120	ATPase activity
E0L14_RS15670	COG1091	dTDP-4-dehydrorhamnose reductase activity
E0L14_RS15700	COG2205	protein histidine kinase activity
E0L14_RS15705	COG2759	Belongs to the formate--tetrahydrofolate ligase family
E0L14_RS15715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E0L14_RS15730	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
E0L14_RS15735	COG0540	Belongs to the ATCase OTCase family
E0L14_RS15745	COG2431	L-lysine efflux transmembrane transporter activity
E0L14_RS15775	COG2837	iron assimilation
E0L14_RS15790	COG4206	TonB-dependent receptor
E0L14_RS15790	COG1629	transport
E0L14_RS15810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E0L14_RS15830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E0L14_RS15850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
E0L14_RS15855	COG2205	protein histidine kinase activity
E0L14_RS16100	COG0629	single-stranded DNA binding
E0L14_RS16105	COG0358	DNA primase activity
E0L14_RS16170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E0L14_RS16175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E0L14_RS16190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E0L14_RS16200	COG0673	inositol 2-dehydrogenase activity
E0L14_RS16215	COG2223	nitrite transmembrane transporter activity
E0L14_RS16235	COG0671	phosphoesterase, PA-phosphatase related
E0L14_RS16255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E0L14_RS16260	COG0045	succinate-CoA ligase (ADP-forming) activity
E0L14_RS16265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E0L14_RS16270	COG0351	phosphomethylpyrimidine kinase
E0L14_RS16280	COG1070	Carbohydrate kinase
E0L14_RS16285	COG2115	Belongs to the xylose isomerase family
E0L14_RS16290	COG2814	Major facilitator Superfamily
E0L14_RS16290	COG0477	Major facilitator Superfamily
E0L14_RS16300	COG3153	acetyltransferase
E0L14_RS16300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E0L14_RS16305	COG0450	alkyl hydroperoxide reductase
E0L14_RS16310	COG0724	RNA recognition motif
E0L14_RS16315	COG1858	cytochrome C peroxidase
E0L14_RS16320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E0L14_RS16350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E0L14_RS16360	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E0L14_RS16375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E0L14_RS16440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E0L14_RS16450	COG1904	glucuronate isomerase
E0L14_RS16480	COG0513	Belongs to the DEAD box helicase family
E0L14_RS16485	COG3830	Belongs to the UPF0237 family
E0L14_RS16485	COG0560	Phosphoserine phosphatase
E0L14_RS16505	COG0343	queuine tRNA-ribosyltransferase activity
E0L14_RS16510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
E0L14_RS16515	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E0L14_RS16805	COG2205	protein histidine kinase activity
E0L14_RS16810	COG2204	response regulator
E0L14_RS16860	COG0577	efflux transmembrane transporter activity
E0L14_RS16860	COG1136	(ABC) transporter
E0L14_RS16870	COG0156	8-amino-7-oxononanoate synthase activity
E0L14_RS16875	COG1597	lipid kinase activity
E0L14_RS16880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E0L14_RS16905	COG0577	efflux transmembrane transporter activity
E0L14_RS16905	COG1136	(ABC) transporter
E0L14_RS16930	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E0L14_RS16960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E0L14_RS16980	COG0543	2 iron, 2 sulfur cluster binding
E0L14_RS16985	COG0167	dihydroorotate dehydrogenase activity
E0L14_RS16995	COG0336	Belongs to the RNA methyltransferase TrmD family
E0L14_RS17000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E0L14_RS17005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E0L14_RS17015	COG2315	Protein conserved in bacteria
E0L14_RS17045	COG0326	Molecular chaperone. Has ATPase activity
E0L14_RS17050	COG0542	response to heat
E0L14_RS17095	COG2304	oxidoreductase activity
E0L14_RS17110	COG0714	Associated with various cellular activities
E0L14_RS17115	COG1652	LysM domain
E0L14_RS17125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E0L14_RS17130	COG0552	protein localization to endoplasmic reticulum
E0L14_RS17140	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E0L14_RS17145	COG0227	Belongs to the bacterial ribosomal protein bL28 family
E0L14_RS17150	COG1546	Belongs to the CinA family
E0L14_RS17150	COG1058	Belongs to the CinA family
E0L14_RS17155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
E0L14_RS17170	COG0442	prolyl-tRNA aminoacylation
E0L14_RS17185	COG4946	Tricorn protease homolog
E0L14_RS17185	COG0793	Belongs to the peptidase S41A family
E0L14_RS17200	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
E0L14_RS17205	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
E0L14_RS17220	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
E0L14_RS17230	COG1492	cobalamin metabolic process
E0L14_RS17280	COG0784	Response regulator, receiver
E0L14_RS17280	COG5002	protein histidine kinase activity
E0L14_RS17280	COG2198	Histidine kinase
E0L14_RS17285	COG2096	Adenosyltransferase
E0L14_RS17290	COG1797	cobyrinic acid a,c-diamide synthase activity
E0L14_RS17305	COG2966	Psort location CytoplasmicMembrane, score
E0L14_RS17320	COG4771	TonB-dependent receptor
E0L14_RS17330	COG4774	siderophore transport
E0L14_RS17340	COG1429	ligase activity, forming nitrogen-metal bonds
E0L14_RS17375	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
E0L14_RS17450	COG0352	thiamine-phosphate diphosphorylase activity
E0L14_RS17455	COG2022	thiamine diphosphate biosynthetic process
E0L14_RS17460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
E0L14_RS17480	COG0352	thiamine-phosphate diphosphorylase activity
E0L14_RS17495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
E0L14_RS17495	COG0574	Belongs to the PEP-utilizing enzyme family
E0L14_RS17500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
E0L14_RS17505	COG0564	pseudouridine synthase activity
E0L14_RS17525	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
E0L14_RS17545	COG0024	Methionine aminopeptidase
E0L14_RS17560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
E0L14_RS17570	COG0481	GTPase activity
E0L14_RS17590	COG0708	Exodeoxyribonuclease III
E0L14_RS17595	COG1914	H( )-stimulated, divalent metal cation uptake system
E0L14_RS17610	COG0217	transcriptional regulatory protein
E0L14_RS17615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E0L14_RS17615	COG0072	phenylalanine-tRNA ligase activity
E0L14_RS17620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS17625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS17630	COG0297	glycogen (starch) synthase activity
E0L14_RS17635	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS17640	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS17650	COG1216	Glycosyl transferase, family 2
E0L14_RS17660	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS17665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS17710	COG0305	Participates in initiation and elongation during chromosome replication
E0L14_RS17715	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E0L14_RS17730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E0L14_RS17735	COG4657	Part of a membrane complex involved in electron transport
E0L14_RS17740	COG4660	Part of a membrane complex involved in electron transport
E0L14_RS17745	COG4659	FMN binding
E0L14_RS17750	COG4658	electron transport chain
E0L14_RS17755	COG4656	Part of a membrane complex involved in electron transport
E0L14_RS17785	COG0504	CTP synthase activity
E0L14_RS17790	COG0706	membrane insertase activity
E0L14_RS17795	COG0534	Mate efflux family protein
E0L14_RS17800	COG0823	Involved in the tonB-independent uptake of proteins
E0L14_RS17800	COG1506	peptidase
E0L14_RS17815	COG1695	Transcriptional regulator
E0L14_RS17830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E0L14_RS17840	COG1388	LysM domain
E0L14_RS17840	COG3942	CHAP domain
E0L14_RS17870	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
E0L14_RS17880	COG0556	nucleotide-excision repair
E0L14_RS17890	COG2949	membrane
E0L14_RS17900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E0L14_RS17910	COG0784	Response regulator, receiver
E0L14_RS17910	COG2205	protein histidine kinase activity
E0L14_RS17920	COG0842	Transport permease protein
E0L14_RS17925	COG1131	(ABC) transporter
E0L14_RS17955	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
E0L14_RS17960	COG0505	Belongs to the CarA family
E0L14_RS17970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
E0L14_RS17975	COG0367	asparagine synthase
E0L14_RS18000	COG0436	Aminotransferase
E0L14_RS18010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E0L14_RS18020	COG1979	alcohol dehydrogenase
E0L14_RS18040	COG0133	tryptophan synthase activity
E0L14_RS18045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E0L14_RS18050	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E0L14_RS18050	COG0512	Glutamine amidotransferase of anthranilate synthase
E0L14_RS18055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E0L14_RS18060	COG0134	indole-3-glycerol-phosphate synthase activity
E0L14_RS18065	COG0135	phosphoribosylanthranilate isomerase activity
E0L14_RS18070	COG0159	tryptophan synthase activity
E0L14_RS18080	COG0252	asparaginase activity
E0L14_RS18095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
E0L14_RS18105	COG0110	maltose O-acetyltransferase activity
E0L14_RS18110	COG2197	response regulator
E0L14_RS18120	COG0138	bifunctional purine biosynthesis protein purh
E0L14_RS18125	COG0716	FMN binding
E0L14_RS18155	COG1858	cytochrome C peroxidase
E0L14_RS18165	COG4771	TonB-dependent receptor
E0L14_RS18180	COG2814	Major facilitator Superfamily
E0L14_RS18185	COG1566	PFAM secretion protein HlyD family protein
E0L14_RS18225	COG4771	TonB-dependent receptor
E0L14_RS18250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E0L14_RS18255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E0L14_RS18270	COG2966	Psort location CytoplasmicMembrane, score
E0L14_RS18275	COG3610	response to peptide
E0L14_RS18290	COG1609	Transcriptional regulator
E0L14_RS18300	COG1733	regulation of RNA biosynthetic process
E0L14_RS18310	COG2205	protein histidine kinase activity
E0L14_RS18310	COG2198	Histidine kinase
E0L14_RS18310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E0L14_RS18310	COG0784	Response regulator, receiver
E0L14_RS18335	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
E0L14_RS18340	COG1690	Belongs to the RtcB family
E0L14_RS18365	COG0228	four-way junction DNA binding
E0L14_RS18380	COG0724	RNA recognition motif
E0L14_RS18390	COG1177	transmembrane transport
E0L14_RS18395	COG1176	ABC-type spermidine putrescine transport system, permease component I
E0L14_RS18400	COG3842	ATPase activity
E0L14_RS18405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS18415	COG0058	SHG alpha-glucan phosphorylase activity
E0L14_RS18425	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
E0L14_RS18445	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
E0L14_RS18500	COG0745	RESPONSE REGULATOR receiver
E0L14_RS18505	COG5002	protein histidine kinase activity
E0L14_RS18530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E0L14_RS18540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E0L14_RS18550	COG4948	Mandelate Racemase Muconate Lactonizing
E0L14_RS18565	COG1295	ribonuclease BN
E0L14_RS18575	COG0778	Nitroreductase
E0L14_RS18585	COG0704	Plays a role in the regulation of phosphate uptake
E0L14_RS18590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
E0L14_RS18595	COG0581	inorganic phosphate transmembrane transporter activity
E0L14_RS18600	COG0573	inorganic phosphate transmembrane transporter activity
E0L14_RS18610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E0L14_RS18635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E0L14_RS18675	COG3023	N-Acetylmuramoyl-L-alanine amidase
E0L14_RS18725	COG1216	Glycosyl transferase, family 2
E0L14_RS18730	COG1216	Glycosyl transferase, family 2
E0L14_RS18735	COG1215	transferase activity, transferring glycosyl groups
E0L14_RS18755	COG1216	Glycosyl transferase, family 2
E0L14_RS18765	COG1045	serine acetyltransferase
E0L14_RS18770	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS18790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
E0L14_RS18840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
E0L14_RS18880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E0L14_RS18885	COG0167	dihydroorotate dehydrogenase activity
E0L14_RS18950	COG5002	protein histidine kinase activity
E0L14_RS18965	COG2172	sigma factor antagonist activity
E0L14_RS18975	COG2208	phosphoserine phosphatase activity
E0L14_RS19000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E0L14_RS19020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E0L14_RS19025	COG0497	DNA recombination
E0L14_RS19035	COG5002	protein histidine kinase activity
E0L14_RS19035	COG2176	DNA-directed DNA polymerase activity
E0L14_RS19040	COG0592	DNA-directed DNA polymerase activity
E0L14_RS19055	COG0321	lipoyl(octanoyl) transferase activity
E0L14_RS19055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E0L14_RS19060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
E0L14_RS19070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E0L14_RS19080	COG0156	8-amino-7-oxononanoate synthase activity
E0L14_RS19180	COG0019	diaminopimelate decarboxylase activity
E0L14_RS19185	COG0527	aspartate kinase activity
E0L14_RS19190	COG2884	Cell division ATP-binding protein ftsE
E0L14_RS19195	COG0140	phosphoribosyl-ATP diphosphatase activity
E0L14_RS19195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
E0L14_RS19200	COG0107	imidazoleglycerol-phosphate synthase activity
E0L14_RS19205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E0L14_RS19210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E0L14_RS19230	COG3586	endonuclease activity
E0L14_RS19280	COG1472	Belongs to the glycosyl hydrolase 3 family
E0L14_RS19285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
E0L14_RS19295	COG5012	cobalamin binding
E0L14_RS19305	COG1472	Belongs to the glycosyl hydrolase 3 family
E0L14_RS19310	COG0702	epimerase
E0L14_RS19315	COG4771	TonB-dependent receptor
E0L14_RS19335	COG0693	protein deglycase activity
E0L14_RS19350	COG0494	nUDIX hydrolase
E0L14_RS19355	COG1401	restriction endodeoxyribonuclease activity
E0L14_RS19375	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
E0L14_RS19425	COG4977	sequence-specific DNA binding
E0L14_RS19425	COG1917	Cupin 2, conserved barrel domain protein
E0L14_RS19430	COG2814	Major facilitator Superfamily
E0L14_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS19440	COG2207	Transcriptional regulator
E0L14_RS19455	COG1090	epimerase
E0L14_RS19485	COG0561	phosphatase activity
E0L14_RS19490	COG1629	transport
E0L14_RS19490	COG4206	TonB-dependent receptor
E0L14_RS19540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E0L14_RS19550	COG0363	glucosamine-6-phosphate deaminase activity
E0L14_RS19600	COG1032	radical SAM domain protein
E0L14_RS19605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
E0L14_RS19610	COG0463	Glycosyl transferase, family 2
E0L14_RS19615	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E0L14_RS19625	COG1410	methionine synthase
E0L14_RS19625	COG0646	methionine synthase
E0L14_RS19685	COG1408	metallophosphoesterase
E0L14_RS19690	COG1132	(ABC) transporter
E0L14_RS19695	COG1132	(ABC) transporter
E0L14_RS19710	COG0420	3'-5' exonuclease activity
E0L14_RS19730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E0L14_RS19735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS19745	COG0681	Belongs to the peptidase S26 family
E0L14_RS19840	COG0641	radical SAM
E0L14_RS19845	COG3591	Belongs to the peptidase S1B family
E0L14_RS19850	COG3591	Belongs to the peptidase S1B family
E0L14_RS19885	COG1773	rubredoxin
E0L14_RS19885	COG1592	Rubrerythrin
E0L14_RS19895	COG3152	Membrane
E0L14_RS19900	COG0339	signal peptide processing
E0L14_RS19905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
E0L14_RS19905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E0L14_RS19915	COG1629	transport
E0L14_RS19915	COG4206	TonB-dependent receptor
E0L14_RS19930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E0L14_RS19930	COG0131	Imidazoleglycerol-phosphate dehydratase
E0L14_RS19935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
E0L14_RS19940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
E0L14_RS19945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E0L14_RS19955	COG1741	Belongs to the pirin family
E0L14_RS19960	COG4232	protein-disulfide reductase activity
E0L14_RS19970	COG0572	uridine kinase
E0L14_RS19980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E0L14_RS19990	COG0646	methionine synthase
E0L14_RS19990	COG1410	methionine synthase
E0L14_RS19995	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E0L14_RS20030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E0L14_RS20040	COG1295	ribonuclease BN
E0L14_RS20070	COG2202	Pas domain
E0L14_RS20070	COG2205	protein histidine kinase activity
E0L14_RS20075	COG0534	Mate efflux family protein
E0L14_RS20080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E0L14_RS20085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS20090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E0L14_RS20095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E0L14_RS20155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E0L14_RS20195	COG2195	Cleaves the N-terminal amino acid of tripeptides
E0L14_RS20205	COG0668	transmembrane transport
E0L14_RS20210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
E0L14_RS20220	COG3250	beta-galactosidase activity
E0L14_RS20225	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS20230	COG3119	arylsulfatase activity
E0L14_RS20235	COG3119	arylsulfatase activity
E0L14_RS20240	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS20245	COG2205	protein histidine kinase activity
E0L14_RS20245	COG3292	Two component regulator propeller
E0L14_RS20245	COG0745	RESPONSE REGULATOR receiver
E0L14_RS20250	COG1830	Aldolase
E0L14_RS20255	COG0588	phosphoglycerate mutase activity
E0L14_RS20265	COG1119	ATPase activity
E0L14_RS20270	COG3119	arylsulfatase activity
E0L14_RS20275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS20285	COG4206	TonB-dependent receptor
E0L14_RS20285	COG1629	transport
E0L14_RS20295	COG1595	DNA-templated transcription, initiation
E0L14_RS20300	COG1523	belongs to the glycosyl hydrolase 13 family
E0L14_RS20305	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
E0L14_RS20330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E0L14_RS20340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E0L14_RS20345	COG0126	phosphoglycerate kinase activity
E0L14_RS20360	COG2311	Membrane
E0L14_RS20405	COG0424	maF-like protein
E0L14_RS20410	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
E0L14_RS20425	COG0778	Nitroreductase
E0L14_RS20430	COG0288	reversible hydration of carbon dioxide
E0L14_RS20445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E0L14_RS20455	COG0511	ligase activity, forming carbon-carbon bonds
E0L14_RS20455	COG5016	pyruvate
E0L14_RS20460	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
E0L14_RS20475	COG0366	Alpha amylase catalytic
E0L14_RS20495	COG0191	fructose-bisphosphate aldolase activity
E0L14_RS20505	COG0254	rRNA binding
E0L14_RS20530	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
E0L14_RS20535	COG4206	TonB-dependent receptor
E0L14_RS20535	COG1629	transport
E0L14_RS20540	COG1609	Transcriptional regulator
E0L14_RS20550	COG1554	hydrolase, family 65, central catalytic
E0L14_RS20555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS20575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E0L14_RS20575	COG0047	phosphoribosylformylglycinamidine synthase activity
E0L14_RS20580	COG0745	RESPONSE REGULATOR receiver
E0L14_RS20580	COG2205	protein histidine kinase activity
E0L14_RS20580	COG3292	Two component regulator propeller
E0L14_RS20595	COG1649	PFAM Uncharacterised BCR, COG1649
E0L14_RS20615	COG1966	Carbon starvation protein
E0L14_RS20625	COG1649	PFAM Uncharacterised BCR, COG1649
E0L14_RS20630	COG0784	Response regulator, receiver
E0L14_RS20630	COG2205	protein histidine kinase activity
E0L14_RS20670	COG2113	Glycine betaine
E0L14_RS20675	COG4176	ABC-type proline glycine betaine transport system permease component
E0L14_RS20695	COG3292	Two component regulator propeller
E0L14_RS20695	COG2205	protein histidine kinase activity
E0L14_RS20695	COG0745	RESPONSE REGULATOR receiver
E0L14_RS20700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
E0L14_RS20700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
E0L14_RS20710	COG1621	beta-fructofuranosidase activity
E0L14_RS20740	COG0738	Major facilitator superfamily
E0L14_RS20755	COG1752	Esterase of the alpha-beta hydrolase superfamily
E0L14_RS20760	COG0475	glutathione-regulated potassium exporter activity
E0L14_RS20785	COG3015	lipoprotein NlpE involved in copper resistance
E0L14_RS20805	COG4977	sequence-specific DNA binding
E0L14_RS20805	COG1917	Cupin 2, conserved barrel domain protein
E0L14_RS20835	COG4771	TonB-dependent receptor
E0L14_RS20840	COG0702	epimerase
E0L14_RS20855	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E0L14_RS20875	COG0484	heat shock protein binding
E0L14_RS20880	COG0784	Response regulator, receiver
E0L14_RS20880	COG2205	protein histidine kinase activity
E0L14_RS20885	COG2194	sulfuric ester hydrolase activity
E0L14_RS20935	COG0028	Belongs to the TPP enzyme family
E0L14_RS20965	COG0459	protein refolding
E0L14_RS20970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E0L14_RS21010	COG2326	polyphosphate kinase activity
E0L14_RS21055	COG3537	Alpha-1,2-mannosidase
E0L14_RS21060	COG1506	peptidase
E0L14_RS21060	COG0823	Involved in the tonB-independent uptake of proteins
E0L14_RS21065	COG0124	histidyl-tRNA synthetase
E0L14_RS21095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
E0L14_RS21140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E0L14_RS21150	COG0671	phosphoesterase, PA-phosphatase related
E0L14_RS21170	COG0702	epimerase
E0L14_RS21175	COG4771	TonB-dependent receptor
E0L14_RS21205	COG0463	Glycosyl transferase, family 2
E0L14_RS21220	COG0066	3-isopropylmalate dehydratase activity
E0L14_RS21230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E0L14_RS21235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E0L14_RS21290	COG0616	signal peptide processing
E0L14_RS21295	COG1663	tetraacyldisaccharide 4'-kinase activity
E0L14_RS21300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
E0L14_RS21305	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
E0L14_RS21385	COG0667	Aldo Keto reductase
E0L14_RS21425	COG0546	phosphoglycolate phosphatase activity
E0L14_RS21440	COG2207	Transcriptional regulator
E0L14_RS21445	COG0745	RESPONSE REGULATOR receiver
E0L14_RS21445	COG3292	Two component regulator propeller
E0L14_RS21445	COG2205	protein histidine kinase activity
E0L14_RS21450	COG4948	Mandelate Racemase Muconate Lactonizing
E0L14_RS21470	COG0702	epimerase
E0L14_RS21475	COG1629	transport
E0L14_RS21475	COG4206	TonB-dependent receptor
E0L14_RS21505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E0L14_RS21510	COG1917	Cupin 2, conserved barrel domain protein
E0L14_RS21510	COG2207	Transcriptional regulator
E0L14_RS21525	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
E0L14_RS21535	COG3011	Protein conserved in bacteria
E0L14_RS21545	COG1028	Short-chain dehydrogenase reductase Sdr
E0L14_RS21610	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E0L14_RS21625	COG4651	solute:proton antiporter activity
E0L14_RS21625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
E0L14_RS21630	COG0439	Biotin carboxylase
E0L14_RS21635	COG5016	pyruvate
E0L14_RS21635	COG0511	ligase activity, forming carbon-carbon bonds
E0L14_RS21640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E0L14_RS21645	COG1335	isochorismatase
E0L14_RS21665	COG0517	IMP dehydrogenase activity
E0L14_RS21665	COG0516	GMP reductase activity
E0L14_RS21680	COG2207	Transcriptional regulator
E0L14_RS21690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
E0L14_RS21705	COG2873	o-acetylhomoserine
E0L14_RS21765	COG2076	Multidrug Resistance protein
E0L14_RS21800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
E0L14_RS21810	COG0741	lytic transglycosylase activity
E0L14_RS21810	COG1388	LysM domain
E0L14_RS21815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E0L14_RS21820	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E0L14_RS21820	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E0L14_RS21830	COG1285	pathogenesis
E0L14_RS21850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E0L14_RS21850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E0L14_RS21865	COG1115	amino acid carrier protein
E0L14_RS21875	COG1509	lysine 2,3-aminomutase activity
E0L14_RS21880	COG2233	PERMEase
E0L14_RS21900	COG1393	Belongs to the ArsC family
E0L14_RS21910	COG1629	transport
E0L14_RS21910	COG4206	TonB-dependent receptor
E0L14_RS21925	COG4589	Belongs to the CDS family
E0L14_RS21935	COG2304	oxidoreductase activity
E0L14_RS21945	COG0351	phosphomethylpyrimidine kinase
E0L14_RS21955	COG1139	Iron-sulfur cluster binding protein
E0L14_RS21960	COG0247	lactate metabolic process
E0L14_RS21965	COG0602	queuosine metabolic process
E0L14_RS21975	COG2832	Protein of unknown function (DUF454)
E0L14_RS21980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E0L14_RS21995	COG3142	Participates in the control of copper homeostasis
E0L14_RS22000	COG1418	mRNA catabolic process
E0L14_RS22025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E0L14_RS22045	COG4771	TonB-dependent receptor
E0L14_RS22075	COG2189	Belongs to the N(4) N(6)-methyltransferase family
E0L14_RS22210	COG0517	IMP dehydrogenase activity
E0L14_RS22210	COG0617	tRNA 3'-terminal CCA addition
E0L14_RS22210	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E0L14_RS22235	COG0612	Peptidase, M16
E0L14_RS22245	COG1278	Cold shock
E0L14_RS22275	COG0438	transferase activity, transferring glycosyl groups
E0L14_RS22285	COG0463	Glycosyl transferase, family 2
E0L14_RS22285	COG1216	Glycosyl transferase, family 2
E0L14_RS22290	COG1216	Glycosyl transferase, family 2
E0L14_RS22320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E0L14_RS22370	COG0776	regulation of translation
E0L14_RS22375	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E0L14_RS22410	COG0632	four-way junction helicase activity
E0L14_RS22415	COG0673	inositol 2-dehydrogenase activity
E0L14_RS22420	COG1272	protein, Hemolysin III
E0L14_RS22425	COG1328	CTP reductase activity
E0L14_RS22435	COG2814	Major facilitator Superfamily
E0L14_RS22440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E0L14_RS22445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E0L14_RS22455	COG0750	zinc metalloprotease
E0L14_RS22460	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
E0L14_RS22470	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E0L14_RS22475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
E0L14_RS22485	COG1214	PFAM Peptidase M22, glycoprotease
E0L14_RS22505	COG0194	GDP metabolic process
E0L14_RS22510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E0L14_RS22515	COG1408	metallophosphoesterase
E0L14_RS22520	COG1575	Belongs to the MenA family. Type 1 subfamily
E0L14_RS22525	COG1088	dTDP-glucose 4,6-dehydratase activity
E0L14_RS22530	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E0L14_RS22540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
E0L14_RS22550	COG2204	response regulator
E0L14_RS22555	COG0488	(ABC) transporter
E0L14_RS22630	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
E0L14_RS22640	COG1522	sequence-specific DNA binding
E0L14_RS22670	COG0811	peptide transport
E0L14_RS22680	COG0084	hydrolase, TatD family'
E0L14_RS22695	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
E0L14_RS22700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E0L14_RS22705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
E0L14_RS22710	COG0205	6-phosphofructokinase activity
E0L14_RS22730	COG0372	Belongs to the citrate synthase family
E0L14_RS22735	COG0538	isocitrate dehydrogenase activity
E0L14_RS22745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
E0L14_RS22755	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
E0L14_RS22780	COG0129	dihydroxy-acid dehydratase activity
E0L14_RS22805	COG2885	chlorophyll binding
E0L14_RS22825	COG3681	Belongs to the UPF0597 family
E0L14_RS22855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E0L14_RS22865	COG0702	epimerase
E0L14_RS22870	COG4771	TonB-dependent receptor
E0L14_RS22885	COG0702	epimerase
E0L14_RS22890	COG4206	TonB-dependent receptor
E0L14_RS22890	COG1629	transport
E0L14_RS22900	COG3291	Pkd domain containing protein
E0L14_RS22900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS22910	COG4771	TonB-dependent receptor
E0L14_RS22925	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
E0L14_RS22965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E0L14_RS22965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E0L14_RS22970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
E0L14_RS23010	COG0534	Mate efflux family protein
E0L14_RS23015	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E0L14_RS23020	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E0L14_RS23025	COG0166	Belongs to the GPI family
E0L14_RS23035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E0L14_RS23045	COG2502	aspartate--ammonia ligase
E0L14_RS23050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E0L14_RS23065	COG3525	Glycosyl hydrolase, family 20, catalytic domain
E0L14_RS23085	COG0860	N-Acetylmuramoyl-L-alanine amidase
E0L14_RS23140	COG4227	nucleotidyltransferase activity
E0L14_RS23250	COG1196	nuclear chromosome segregation
E0L14_RS23250	COG0739	heme binding
E0L14_RS23250	COG0741	lytic transglycosylase activity
E0L14_RS23290	COG0776	regulation of translation