locus-tag	class	description
EC81_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EC81_RS00020	COG1640	4-alpha-glucanotransferase
EC81_RS00030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC81_RS00035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC81_RS00060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC81_RS00065	COG1022	Amp-dependent synthetase and ligase
EC81_RS00080	COG0359	binds to the 23S rRNA
EC81_RS00085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EC81_RS00090	COG0360	Binds together with S18 to 16S ribosomal RNA
EC81_RS00110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC81_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC81_RS00160	COG4771	TonB-dependent receptor
EC81_RS00175	COG2431	L-lysine efflux transmembrane transporter activity
EC81_RS00185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS00190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS00200	COG0438	transferase activity, transferring glycosyl groups
EC81_RS00210	COG1216	Glycosyl transferase, family 2
EC81_RS00255	COG2089	acid synthase
EC81_RS00260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS00265	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
EC81_RS00270	COG1086	Polysaccharide biosynthesis protein
EC81_RS00330	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EC81_RS00335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EC81_RS00340	COG0386	Belongs to the glutathione peroxidase family
EC81_RS00360	COG3275	phosphorelay sensor kinase activity
EC81_RS00365	COG3279	Response regulator of the LytR AlgR family
EC81_RS00375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EC81_RS00385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EC81_RS00400	COG3250	beta-galactosidase activity
EC81_RS00405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC81_RS00415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EC81_RS00420	COG0658	competence protein
EC81_RS00425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC81_RS00430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EC81_RS00440	COG0009	L-threonylcarbamoyladenylate synthase
EC81_RS00465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS00470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS00480	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EC81_RS00485	COG0438	transferase activity, transferring glycosyl groups
EC81_RS00525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS00535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC81_RS00540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EC81_RS00555	COG4750	Nucleotidyl transferase
EC81_RS00595	COG0519	Catalyzes the synthesis of GMP from XMP
EC81_RS00605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EC81_RS00605	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EC81_RS00610	COG0514	ATP-dependent DNA helicase (RecQ)
EC81_RS00620	COG2271	Major facilitator Superfamily
EC81_RS00635	COG0702	epimerase
EC81_RS00640	COG4771	TonB-dependent receptor
EC81_RS00645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC81_RS00650	COG2186	Transcriptional regulator
EC81_RS00665	COG0436	Aminotransferase
EC81_RS00670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EC81_RS00685	COG0358	DNA primase activity
EC81_RS00690	COG3119	arylsulfatase activity
EC81_RS00695	COG0702	epimerase
EC81_RS00700	COG4206	TonB-dependent receptor
EC81_RS00700	COG1629	transport
EC81_RS00715	COG0302	gtp cyclohydrolase
EC81_RS00725	COG0149	triose-phosphate isomerase activity
EC81_RS00740	COG0739	heme binding
EC81_RS00745	COG0105	UTP biosynthetic process
EC81_RS00750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EC81_RS00775	COG0811	peptide transport
EC81_RS00785	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EC81_RS00830	COG1629	transport
EC81_RS00860	COG0823	Involved in the tonB-independent uptake of proteins
EC81_RS00860	COG4946	Tricorn protease homolog
EC81_RS00860	COG1506	peptidase
EC81_RS00865	COG0039	L-malate dehydrogenase activity
EC81_RS00895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS00920	COG3118	belongs to the thioredoxin family
EC81_RS00925	COG0489	protein tyrosine kinase activity
EC81_RS00940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC81_RS00945	COG1722	exodeoxyribonuclease VII activity
EC81_RS00950	COG1570	exodeoxyribonuclease VII activity
EC81_RS00960	COG0482	sulfurtransferase activity
EC81_RS00985	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EC81_RS00990	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC81_RS00995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EC81_RS01005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EC81_RS01010	COG0052	Belongs to the universal ribosomal protein uS2 family
EC81_RS01015	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EC81_RS01020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EC81_RS01035	COG0017	Asparaginyl-tRNA synthetase
EC81_RS01040	COG1187	pseudouridine synthase activity
EC81_RS01080	COG0110	maltose O-acetyltransferase activity
EC81_RS01085	COG3022	response to hydroperoxide
EC81_RS01090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS01150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC81_RS01190	COG1216	Glycosyl transferase, family 2
EC81_RS01190	COG1442	glycosyl transferase family 8
EC81_RS01225	COG0438	transferase activity, transferring glycosyl groups
EC81_RS01330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EC81_RS01345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC81_RS01360	COG0516	GMP reductase activity
EC81_RS01360	COG0517	IMP dehydrogenase activity
EC81_RS01365	COG0514	ATP-dependent DNA helicase (RecQ)
EC81_RS01370	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EC81_RS01380	COG0544	peptidyl-prolyl cis-trans isomerase activity
EC81_RS01385	COG0724	RNA recognition motif
EC81_RS01395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC81_RS01400	COG1127	ABC transporter
EC81_RS01405	COG0745	RESPONSE REGULATOR receiver
EC81_RS01410	COG1160	GTP binding
EC81_RS01415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EC81_RS01420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC81_RS01470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EC81_RS01475	COG0470	DNA polymerase III
EC81_RS01480	COG1774	PSP1 C-terminal conserved region
EC81_RS01490	COG0772	Belongs to the SEDS family
EC81_RS01505	COG1792	Involved in formation and maintenance of cell shape
EC81_RS01515	COG0138	bifunctional purine biosynthesis protein purh
EC81_RS01520	COG3590	peptidase
EC81_RS01525	COG0488	(ABC) transporter
EC81_RS01580	COG2205	protein histidine kinase activity
EC81_RS01580	COG0784	Response regulator, receiver
EC81_RS01585	COG0534	Mate efflux family protein
EC81_RS01590	COG0612	Peptidase, M16
EC81_RS01595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EC81_RS01610	COG0564	pseudouridine synthase activity
EC81_RS01865	COG0358	DNA primase activity
EC81_RS01940	COG1131	(ABC) transporter
EC81_RS02030	COG1696	Membrane protein involved in D-alanine export
EC81_RS02065	COG1309	transcriptional regulator
EC81_RS02070	COG2986	histidine ammonia-lyase
EC81_RS02080	COG1228	amidohydrolase
EC81_RS02090	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EC81_RS02100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC81_RS02115	COG0203	ribosomal protein L17
EC81_RS02120	COG0202	RNA polymerase activity
EC81_RS02125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EC81_RS02130	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EC81_RS02135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EC81_RS02140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EC81_RS02145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EC81_RS02160	COG0200	Binds to the 23S rRNA
EC81_RS02165	COG1841	ribosomal large subunit assembly
EC81_RS02170	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EC81_RS02175	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EC81_RS02180	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EC81_RS02185	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EC81_RS02190	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EC81_RS02195	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EC81_RS02200	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EC81_RS02205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EC81_RS02210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EC81_RS02215	COG0255	Belongs to the universal ribosomal protein uL29 family
EC81_RS02220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EC81_RS02225	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EC81_RS02230	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EC81_RS02235	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EC81_RS02240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EC81_RS02245	COG0089	rRNA binding
EC81_RS02250	COG0088	Forms part of the polypeptide exit tunnel
EC81_RS02255	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EC81_RS02260	COG0051	transcription antitermination factor activity, RNA binding
EC81_RS02265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC81_RS02270	COG0049	tRNA binding
EC81_RS02275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EC81_RS02305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EC81_RS02310	COG0085	RNA polymerase activity
EC81_RS02315	COG0222	ribosome binding
EC81_RS02320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EC81_RS02325	COG0081	regulation of translation
EC81_RS02330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EC81_RS02375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC81_RS02380	COG4974	Belongs to the 'phage' integrase family
EC81_RS02385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EC81_RS02390	COG0006	proline dipeptidase activity
EC81_RS02395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC81_RS02405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC81_RS02410	COG1480	7TM receptor with intracellular HD hydrolase
EC81_RS02415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EC81_RS02425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EC81_RS02440	COG1027	Aspartate ammonia-lyase
EC81_RS02445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC81_RS02450	COG0252	asparaginase activity
EC81_RS02465	COG2096	Adenosyltransferase
EC81_RS02505	COG1629	transport
EC81_RS02535	COG0657	acetylesterase activity
EC81_RS02535	COG2755	lipolytic protein G-D-S-L family
EC81_RS02550	COG3279	Response regulator of the LytR AlgR family
EC81_RS02565	COG4771	TonB-dependent receptor
EC81_RS02585	COG2197	response regulator
EC81_RS02590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC81_RS02595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC81_RS02605	COG4974	Belongs to the 'phage' integrase family
EC81_RS02610	COG4804	nuclease activity
EC81_RS02675	COG0358	DNA primase activity
EC81_RS02710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC81_RS02720	COG1185	polyribonucleotide nucleotidyltransferase activity
EC81_RS02735	COG4771	TonB-dependent receptor
EC81_RS02780	COG3426	butyrate kinase activity
EC81_RS02785	COG0280	phosphate acetyltransferase
EC81_RS02795	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC81_RS02800	COG2234	aminopeptidase activity
EC81_RS02805	COG2166	iron-sulfur cluster assembly
EC81_RS02810	COG3655	Transcriptional regulator
EC81_RS02820	COG1266	CAAX protease self-immunity
EC81_RS02825	COG0196	riboflavin kinase activity
EC81_RS02830	COG1011	Hydrolase
EC81_RS02835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EC81_RS02840	COG2205	protein histidine kinase activity
EC81_RS02840	COG0784	Response regulator, receiver
EC81_RS02845	COG1773	rubredoxin
EC81_RS02850	COG1283	sodium-dependent phosphate transmembrane transporter activity
EC81_RS02860	COG2205	protein histidine kinase activity
EC81_RS02885	COG0006	proline dipeptidase activity
EC81_RS02900	COG0509	glycine decarboxylation via glycine cleavage system
EC81_RS02905	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EC81_RS02925	COG0793	Belongs to the peptidase S41A family
EC81_RS02930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC81_RS02970	COG4771	TonB-dependent receptor
EC81_RS02975	COG0745	RESPONSE REGULATOR receiver
EC81_RS02975	COG3292	Two component regulator propeller
EC81_RS02975	COG2205	protein histidine kinase activity
EC81_RS02980	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC81_RS02985	COG1882	Formate acetyltransferase
EC81_RS02990	COG0477	Major facilitator Superfamily
EC81_RS02990	COG2814	Major facilitator Superfamily
EC81_RS03015	COG0483	inositol monophosphate 1-phosphatase activity
EC81_RS03025	COG3345	alpha-galactosidase
EC81_RS03050	COG3475	LICD family
EC81_RS03055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC81_RS03085	COG1442	glycosyl transferase family 8
EC81_RS03125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EC81_RS03140	COG0438	transferase activity, transferring glycosyl groups
EC81_RS03160	COG2816	NAD+ diphosphatase activity
EC81_RS03215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC81_RS03225	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC81_RS03225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC81_RS03230	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC81_RS03235	COG0584	glycerophosphoryl diester phosphodiesterase
EC81_RS03240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EC81_RS03245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EC81_RS03250	COG1629	transport
EC81_RS03285	COG1629	transport
EC81_RS03300	COG1217	gtp-binding protein TYPA
EC81_RS03305	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EC81_RS03315	COG0318	PFAM AMP-dependent synthetase and ligase
EC81_RS03340	COG3119	arylsulfatase activity
EC81_RS03350	COG4206	TonB-dependent receptor
EC81_RS03350	COG1629	transport
EC81_RS03370	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC81_RS03375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EC81_RS03390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EC81_RS03395	COG4974	Belongs to the 'phage' integrase family
EC81_RS03410	COG0606	chelatase, subunit chli
EC81_RS03475	COG4974	Belongs to the 'phage' integrase family
EC81_RS03515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC81_RS03515	COG0551	DNA topoisomerase type I activity
EC81_RS03555	COG3344	reverse transcriptase
EC81_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS03590	COG0577	efflux transmembrane transporter activity
EC81_RS03710	COG0358	DNA primase activity
EC81_RS03825	COG0438	transferase activity, transferring glycosyl groups
EC81_RS03850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC81_RS03855	COG0438	transferase activity, transferring glycosyl groups
EC81_RS03865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC81_RS03870	COG0545	Peptidyl-prolyl cis-trans isomerase
EC81_RS03875	COG0545	Peptidyl-prolyl cis-trans isomerase
EC81_RS03880	COG1522	sequence-specific DNA binding
EC81_RS03900	COG3275	phosphorelay sensor kinase activity
EC81_RS03915	COG1566	PFAM secretion protein HlyD family protein
EC81_RS03985	COG4206	TonB-dependent receptor
EC81_RS03985	COG1629	transport
EC81_RS03995	COG2814	Major facilitator Superfamily
EC81_RS04055	COG3292	Two component regulator propeller
EC81_RS04055	COG0745	RESPONSE REGULATOR receiver
EC81_RS04055	COG2205	protein histidine kinase activity
EC81_RS04060	COG1621	beta-fructofuranosidase activity
EC81_RS04105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EC81_RS04110	COG3409	Peptidoglycan-binding domain 1 protein
EC81_RS04110	COG0793	Belongs to the peptidase S41A family
EC81_RS04135	COG1053	succinate dehydrogenase
EC81_RS04140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC81_RS04165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC81_RS04165	COG0758	DNA mediated transformation
EC81_RS04175	COG0826	peptidase U32
EC81_RS04185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC81_RS04200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EC81_RS04205	COG0557	exoribonuclease II activity
EC81_RS04230	COG1595	DNA-templated transcription, initiation
EC81_RS04250	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC81_RS04265	COG0012	GTP binding
EC81_RS04270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EC81_RS04275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EC81_RS04285	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC81_RS04295	COG0495	leucyl-tRNA aminoacylation
EC81_RS04300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EC81_RS04325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EC81_RS04345	COG0731	radical SAM domain protein
EC81_RS04345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EC81_RS04370	COG0659	secondary active sulfate transmembrane transporter activity
EC81_RS04375	COG1592	Rubrerythrin
EC81_RS04380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EC81_RS04400	COG0427	acetyl-CoA hydrolase
EC81_RS04410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC81_RS04420	COG3250	beta-galactosidase activity
EC81_RS04530	COG2177	Part of the ABC transporter FtsEX involved in
EC81_RS04540	COG1968	undecaprenyl-diphosphatase activity
EC81_RS04545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EC81_RS04550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EC81_RS04555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EC81_RS04565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EC81_RS04570	COG1611	Belongs to the LOG family
EC81_RS04585	COG0594	ribonuclease P activity
EC81_RS04590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EC81_RS04605	COG4946	Tricorn protease homolog
EC81_RS04605	COG1506	peptidase
EC81_RS04605	COG0823	Involved in the tonB-independent uptake of proteins
EC81_RS04615	COG3119	arylsulfatase activity
EC81_RS04620	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EC81_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS04630	COG4677	pectinesterase activity
EC81_RS04635	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC81_RS04655	COG1121	(ABC) transporter
EC81_RS04665	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EC81_RS04665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC81_RS04685	COG1506	peptidase
EC81_RS04685	COG0823	Involved in the tonB-independent uptake of proteins
EC81_RS04690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EC81_RS04690	COG0116	Belongs to the methyltransferase superfamily
EC81_RS04695	COG1045	serine acetyltransferase
EC81_RS04700	COG3275	phosphorelay sensor kinase activity
EC81_RS04705	COG3279	Response regulator of the LytR AlgR family
EC81_RS04715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC81_RS04715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC81_RS04735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EC81_RS04740	COG1694	Mazg nucleotide pyrophosphohydrolase
EC81_RS04750	COG0322	excinuclease ABC activity
EC81_RS04755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EC81_RS04785	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EC81_RS04790	COG2715	membrane protein required for spore maturation
EC81_RS04800	COG2255	four-way junction helicase activity
EC81_RS04815	COG3591	Belongs to the peptidase S1B family
EC81_RS04845	COG0513	Belongs to the DEAD box helicase family
EC81_RS04855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC81_RS04870	COG0612	Peptidase, M16
EC81_RS04890	COG1312	Catalyzes the dehydration of D-mannonate
EC81_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS04905	COG0681	Belongs to the peptidase S26 family
EC81_RS04915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EC81_RS04945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC81_RS04960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS04965	COG3250	beta-galactosidase activity
EC81_RS04985	COG0215	cysteine-tRNA ligase activity
EC81_RS04995	COG0561	phosphatase activity
EC81_RS05000	COG0745	RESPONSE REGULATOR receiver
EC81_RS05060	COG0205	6-phosphofructokinase activity
EC81_RS05070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC81_RS05075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EC81_RS05080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EC81_RS05085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC81_RS05095	COG1216	Glycosyl transferase, family 2
EC81_RS05115	COG1442	glycosyl transferase family 8
EC81_RS05120	COG1216	Glycosyl transferase, family 2
EC81_RS05120	COG1442	glycosyl transferase family 8
EC81_RS05130	COG1442	glycosyl transferase family 8
EC81_RS05130	COG1216	Glycosyl transferase, family 2
EC81_RS05135	COG1132	(ABC) transporter
EC81_RS05140	COG0328	RNA-DNA hybrid ribonuclease activity
EC81_RS05140	COG3341	Caulimovirus viroplasmin
EC81_RS05150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC81_RS05160	COG0326	Molecular chaperone. Has ATPase activity
EC81_RS05170	COG1166	arginine decarboxylase activity
EC81_RS05175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC81_RS05180	COG1595	DNA-templated transcription, initiation
EC81_RS05225	COG1454	alcohol dehydrogenase
EC81_RS05230	COG0235	Class ii aldolase
EC81_RS05235	COG1070	Carbohydrate kinase
EC81_RS05240	COG0738	Major facilitator superfamily
EC81_RS05260	COG0779	Required for maturation of 30S ribosomal subunits
EC81_RS05265	COG0195	Participates in both transcription termination and antitermination
EC81_RS05270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EC81_RS05280	COG0719	Fe-S assembly protein
EC81_RS05290	COG0396	ATPase activity
EC81_RS05295	COG0719	Fe-S assembly protein
EC81_RS05300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC81_RS05305	COG0393	Putative heavy-metal-binding
EC81_RS05310	COG3345	alpha-galactosidase
EC81_RS05320	COG4771	TonB-dependent receptor
EC81_RS05345	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EC81_RS05350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EC81_RS05375	COG0187	DNA topoisomerase II activity
EC81_RS05380	COG0268	Binds directly to 16S ribosomal RNA
EC81_RS05390	COG1381	Involved in DNA repair and RecF pathway recombination
EC81_RS05395	COG1610	YqeY-like protein
EC81_RS05400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EC81_RS05415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC81_RS05420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EC81_RS05425	COG0772	Belongs to the SEDS family
EC81_RS05430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EC81_RS05435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS05440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC81_RS05455	COG0275	rRNA processing
EC81_RS05460	COG2001	Belongs to the MraZ family
EC81_RS05495	COG4771	TonB-dependent receptor
EC81_RS05525	COG0756	dUTP diphosphatase activity
EC81_RS05540	COG4942	peptidase
EC81_RS05545	COG3292	Two component regulator propeller
EC81_RS05545	COG0745	RESPONSE REGULATOR receiver
EC81_RS05545	COG2205	protein histidine kinase activity
EC81_RS05550	COG3940	Belongs to the glycosyl hydrolase 43 family
EC81_RS05560	COG3250	beta-galactosidase activity
EC81_RS05590	COG0383	alpha-mannosidase activity
EC81_RS05590	COG0383	alpha-mannosidase activity
EC81_RS05595	COG1629	transport
EC81_RS05595	COG4206	TonB-dependent receptor
EC81_RS05615	COG3507	Belongs to the glycosyl hydrolase 43 family
EC81_RS05635	COG3537	Alpha-1,2-mannosidase
EC81_RS05645	COG2017	converts alpha-aldose to the beta-anomer
EC81_RS05690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC81_RS05695	COG1022	Amp-dependent synthetase and ligase
EC81_RS05710	COG2954	triphosphatase activity
EC81_RS05730	COG3250	beta-galactosidase activity
EC81_RS05735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS05740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EC81_RS05745	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EC81_RS05765	COG4206	TonB-dependent receptor
EC81_RS05765	COG1629	transport
EC81_RS05770	COG2205	protein histidine kinase activity
EC81_RS05770	COG0745	RESPONSE REGULATOR receiver
EC81_RS05770	COG3292	Two component regulator propeller
EC81_RS05775	COG0745	RESPONSE REGULATOR receiver
EC81_RS05775	COG2205	protein histidine kinase activity
EC81_RS05775	COG3292	Two component regulator propeller
EC81_RS05800	COG4771	TonB-dependent receptor
EC81_RS05840	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
EC81_RS05890	COG4771	TonB-dependent receptor
EC81_RS05915	COG0423	glycine-tRNA ligase activity
EC81_RS05940	COG3005	denitrification pathway
EC81_RS05945	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EC81_RS05955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC81_RS05975	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EC81_RS05995	COG3876	Protein conserved in bacteria
EC81_RS06015	COG1216	Glycosyl transferase, family 2
EC81_RS06015	COG0463	Glycosyl transferase, family 2
EC81_RS06030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC81_RS06035	COG3876	Protein conserved in bacteria
EC81_RS06045	COG4206	TonB-dependent receptor
EC81_RS06045	COG1629	transport
EC81_RS06055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC81_RS06060	COG0475	glutathione-regulated potassium exporter activity
EC81_RS06060	COG0589	response to stress
EC81_RS06065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EC81_RS06100	COG0733	neurotransmitter:sodium symporter activity
EC81_RS06110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EC81_RS06125	COG0076	glutamate decarboxylase activity
EC81_RS06130	COG2066	Belongs to the glutaminase family
EC81_RS06140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EC81_RS06145	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EC81_RS06260	COG1346	cytolysis
EC81_RS06285	COG0280	phosphate acetyltransferase
EC81_RS06290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EC81_RS06295	COG1785	Belongs to the alkaline phosphatase family
EC81_RS06305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC81_RS06310	COG2003	Belongs to the UPF0758 family
EC81_RS06315	COG1216	Glycosyl transferase, family 2
EC81_RS06315	COG0463	Glycosyl transferase, family 2
EC81_RS06320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EC81_RS06325	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EC81_RS06330	COG0515	serine threonine protein kinase
EC81_RS06330	COG2815	serine threonine protein kinase
EC81_RS06335	COG0564	pseudouridine synthase activity
EC81_RS06380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EC81_RS06385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EC81_RS06395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EC81_RS06415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EC81_RS06425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC81_RS06425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC81_RS06430	COG2890	protein-(glutamine-N5) methyltransferase activity
EC81_RS06435	COG2137	regulation of response to DNA damage stimulus
EC81_RS06440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EC81_RS06465	COG1929	Belongs to the glycerate kinase type-1 family
EC81_RS06475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC81_RS06480	COG1917	Cupin 2, conserved barrel domain protein
EC81_RS06480	COG1396	sequence-specific DNA binding
EC81_RS06485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EC81_RS06490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC81_RS06495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EC81_RS06500	COG0137	argininosuccinate synthase activity
EC81_RS06525	COG0531	amino acid
EC81_RS06535	COG0039	L-malate dehydrogenase activity
EC81_RS06540	COG2996	Protein conserved in bacteria
EC81_RS06565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC81_RS06570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC81_RS06595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS06600	COG1136	(ABC) transporter
EC81_RS06600	COG0577	efflux transmembrane transporter activity
EC81_RS06605	COG0577	efflux transmembrane transporter activity
EC81_RS06605	COG1136	(ABC) transporter
EC81_RS06610	COG1136	(ABC) transporter
EC81_RS06615	COG1940	carbohydrate kinase activity
EC81_RS06620	COG0335	large ribosomal subunit rRNA binding
EC81_RS06625	COG0737	Belongs to the 5'-nucleotidase family
EC81_RS06630	COG0737	Belongs to the 5'-nucleotidase family
EC81_RS06635	COG1472	Belongs to the glycosyl hydrolase 3 family
EC81_RS06640	COG1472	Belongs to the glycosyl hydrolase 3 family
EC81_RS06645	COG4206	TonB-dependent receptor
EC81_RS06645	COG1629	transport
EC81_RS06655	COG3119	arylsulfatase activity
EC81_RS06680	COG0446	pyridine nucleotide-disulphide oxidoreductase
EC81_RS06700	COG2204	response regulator
EC81_RS06710	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EC81_RS06730	COG2205	protein histidine kinase activity
EC81_RS06735	COG5002	protein histidine kinase activity
EC81_RS06750	COG4771	TonB-dependent receptor
EC81_RS06790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EC81_RS06790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EC81_RS06795	COG0436	Aminotransferase
EC81_RS06810	COG0826	peptidase U32
EC81_RS06820	COG4771	TonB-dependent receptor
EC81_RS06830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EC81_RS06840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EC81_RS06850	COG0489	protein tyrosine kinase activity
EC81_RS06850	COG3206	protein involved in exopolysaccharide biosynthesis
EC81_RS06860	COG0527	aspartate kinase activity
EC81_RS06860	COG0460	homoserine dehydrogenase
EC81_RS06865	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
EC81_RS06920	COG4771	TonB-dependent receptor
EC81_RS06925	COG0702	epimerase
EC81_RS06935	COG3250	beta-galactosidase activity
EC81_RS06950	COG3250	beta-galactosidase activity
EC81_RS06955	COG3507	Belongs to the glycosyl hydrolase 43 family
EC81_RS06970	COG4771	TonB-dependent receptor
EC81_RS06985	COG2226	methyltransferase
EC81_RS06995	COG0628	permease
EC81_RS07000	COG1435	thymidine kinase activity
EC81_RS07010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC81_RS07025	COG2095	MarC family integral membrane protein
EC81_RS07035	COG1629	transport
EC81_RS07035	COG4206	TonB-dependent receptor
EC81_RS07045	COG4974	Belongs to the 'phage' integrase family
EC81_RS07050	COG4206	TonB-dependent receptor
EC81_RS07050	COG1629	transport
EC81_RS07060	COG4771	TonB-dependent receptor
EC81_RS07065	COG0702	epimerase
EC81_RS07070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EC81_RS07090	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC81_RS07090	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC81_RS07105	COG0531	amino acid
EC81_RS07115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC81_RS07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS07125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS07165	COG1162	GTPase activity
EC81_RS07170	COG0233	cytoplasmic translational termination
EC81_RS07190	COG0443	Heat shock 70 kDa protein
EC81_RS07200	COG0528	UMP kinase activity
EC81_RS07205	COG0534	Mate efflux family protein
EC81_RS07240	COG0792	nuclease activity
EC81_RS07260	COG1183	phosphatidylcholine synthase activity
EC81_RS07265	COG0688	phosphatidylethanolamine metabolic process
EC81_RS07275	COG3118	belongs to the thioredoxin family
EC81_RS07310	COG0714	Associated with various cellular activities
EC81_RS07325	COG0802	atpase or kinase
EC81_RS07330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC81_RS07340	COG2234	aminopeptidase activity
EC81_RS07405	COG2205	protein histidine kinase activity
EC81_RS07405	COG2198	Histidine kinase
EC81_RS07405	COG0784	Response regulator, receiver
EC81_RS07415	COG4771	TonB-dependent receptor
EC81_RS07420	COG3292	Two component regulator propeller
EC81_RS07420	COG0745	RESPONSE REGULATOR receiver
EC81_RS07420	COG2205	protein histidine kinase activity
EC81_RS07430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS07455	COG2271	Major facilitator Superfamily
EC81_RS07495	COG4771	TonB-dependent receptor
EC81_RS07500	COG0702	epimerase
EC81_RS07510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS07530	COG4771	TonB-dependent receptor
EC81_RS07605	COG1192	Involved in chromosome partitioning
EC81_RS07755	COG1629	transport
EC81_RS07775	COG3250	beta-galactosidase activity
EC81_RS07790	COG0784	Response regulator, receiver
EC81_RS07790	COG2205	protein histidine kinase activity
EC81_RS07810	COG1566	PFAM secretion protein HlyD family protein
EC81_RS07830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EC81_RS07845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC81_RS07850	COG0742	ribosomal rna small subunit methyltransferase
EC81_RS07875	COG4771	TonB-dependent receptor
EC81_RS07885	COG3537	Alpha-1,2-mannosidase
EC81_RS07900	COG3537	Alpha-1,2-mannosidase
EC81_RS07905	COG2814	Major facilitator Superfamily
EC81_RS07930	COG0739	heme binding
EC81_RS07940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC81_RS07945	COG3942	CHAP domain
EC81_RS07945	COG1388	LysM domain
EC81_RS07955	COG1475	DNA binding
EC81_RS07960	COG1192	Involved in chromosome partitioning
EC81_RS07970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EC81_RS07975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC81_RS07990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC81_RS07995	COG0799	negative regulation of ribosome biogenesis
EC81_RS08010	COG2239	Acts as a magnesium transporter
EC81_RS08015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EC81_RS08025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC81_RS08090	COG0668	transmembrane transport
EC81_RS08095	COG2207	Transcriptional regulator
EC81_RS08095	COG0662	Cupin 2, conserved barrel domain protein
EC81_RS08140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS08150	COG2089	acid synthase
EC81_RS08160	COG1083	cytidylyl-transferase
EC81_RS08165	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EC81_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS08175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC81_RS08245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS08250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS08265	COG1373	ATPase (AAA superfamily
EC81_RS08270	COG0667	Aldo Keto reductase
EC81_RS08275	COG1472	Belongs to the glycosyl hydrolase 3 family
EC81_RS08280	COG4771	TonB-dependent receptor
EC81_RS08285	COG0702	epimerase
EC81_RS08325	COG5012	cobalamin binding
EC81_RS08335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EC81_RS08340	COG4124	Belongs to the glycosyl hydrolase 26 family
EC81_RS08345	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EC81_RS08350	COG2211	Major facilitator Superfamily
EC81_RS08355	COG2942	2-epimerase
EC81_RS08395	COG1404	Belongs to the peptidase S8 family
EC81_RS08395	COG4412	M6 family metalloprotease domain protein
EC81_RS08405	COG2205	protein histidine kinase activity
EC81_RS08405	COG5002	protein histidine kinase activity
EC81_RS08405	COG0784	Response regulator, receiver
EC81_RS08415	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC81_RS08420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EC81_RS08425	COG0713	ATP synthesis coupled electron transport
EC81_RS08430	COG0839	Belongs to the complex I subunit 6 family
EC81_RS08440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EC81_RS08445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC81_RS08445	COG0649	NAD binding
EC81_RS08450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC81_RS08455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC81_RS08465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC81_RS08470	COG0569	domain protein
EC81_RS08475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EC81_RS08480	COG1073	alpha beta
EC81_RS08495	COG0546	phosphoglycolate phosphatase activity
EC81_RS08500	COG3119	arylsulfatase activity
EC81_RS08515	COG3119	arylsulfatase activity
EC81_RS08525	COG1629	transport
EC81_RS08530	COG3292	Two component regulator propeller
EC81_RS08530	COG0745	RESPONSE REGULATOR receiver
EC81_RS08530	COG2205	protein histidine kinase activity
EC81_RS08535	COG2271	Major facilitator Superfamily
EC81_RS08555	COG0805	protein transport
EC81_RS08560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC81_RS08565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC81_RS08585	COG4585	Histidine kinase
EC81_RS08600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EC81_RS08610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC81_RS08615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EC81_RS08615	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EC81_RS08620	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC81_RS08625	COG1078	dGTPase activity
EC81_RS08630	COG0284	orotidine-5'-phosphate decarboxylase activity
EC81_RS08635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EC81_RS08640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EC81_RS08650	COG1704	LemA family
EC81_RS08665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC81_RS08670	COG2226	methyltransferase
EC81_RS08675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EC81_RS08680	COG1702	phosphate starvation-inducible protein PhoH
EC81_RS08690	COG2268	Band 7 protein
EC81_RS08700	COG5434	Belongs to the glycosyl hydrolase 28 family
EC81_RS08710	COG0101	tRNA pseudouridine synthase activity
EC81_RS08730	COG3250	beta-galactosidase activity
EC81_RS08735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EC81_RS08765	COG0457	Tetratricopeptide repeat
EC81_RS08770	COG2814	Major facilitator Superfamily
EC81_RS08795	COG0702	epimerase
EC81_RS08800	COG1629	transport
EC81_RS08800	COG4206	TonB-dependent receptor
EC81_RS08815	COG1629	transport
EC81_RS08815	COG4206	TonB-dependent receptor
EC81_RS08825	COG4771	TonB-dependent receptor
EC81_RS08835	COG4206	TonB-dependent receptor
EC81_RS08835	COG1629	transport
EC81_RS08845	COG0673	inositol 2-dehydrogenase activity
EC81_RS08885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EC81_RS08890	COG0793	Belongs to the peptidase S41A family
EC81_RS08895	COG2131	deaminase
EC81_RS08905	COG0339	signal peptide processing
EC81_RS08915	COG1970	mechanosensitive ion channel activity
EC81_RS08920	COG0519	Catalyzes the synthesis of GMP from XMP
EC81_RS08920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC81_RS08930	COG4206	TonB-dependent receptor
EC81_RS08930	COG1629	transport
EC81_RS08940	COG4206	TonB-dependent receptor
EC81_RS08940	COG1629	transport
EC81_RS08945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC81_RS08955	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC81_RS08965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EC81_RS08995	COG1242	4 iron, 4 sulfur cluster binding
EC81_RS09005	COG0363	glucosamine-6-phosphate deaminase activity
EC81_RS09015	COG0009	L-threonylcarbamoyladenylate synthase
EC81_RS09025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC81_RS09030	COG0561	phosphatase activity
EC81_RS09035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC81_RS09040	COG0626	cystathionine gamma-synthase activity
EC81_RS09095	COG0297	glycogen (starch) synthase activity
EC81_RS09100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EC81_RS09105	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EC81_RS09110	COG0543	2 iron, 2 sulfur cluster binding
EC81_RS09120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EC81_RS09130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EC81_RS09135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EC81_RS09150	COG0546	phosphoglycolate phosphatase activity
EC81_RS09155	COG0791	NLP P60 protein
EC81_RS09160	COG1131	(ABC) transporter
EC81_RS09170	COG0612	Peptidase, M16
EC81_RS09175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EC81_RS09180	COG1597	lipid kinase activity
EC81_RS09195	COG1136	(ABC) transporter
EC81_RS09215	COG2211	Major facilitator Superfamily
EC81_RS09225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EC81_RS09245	COG1674	ftsk spoiiie
EC81_RS09255	COG0492	ferredoxin-NADP+ reductase activity
EC81_RS09260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS09300	COG1595	DNA-templated transcription, initiation
EC81_RS09315	COG3956	TIGRFAM MazG family protein
EC81_RS09325	COG0525	valine-tRNA ligase activity
EC81_RS09350	COG4771	TonB-dependent receptor
EC81_RS09365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC81_RS09380	COG4771	TonB-dependent receptor
EC81_RS09385	COG0702	epimerase
EC81_RS09390	COG3119	arylsulfatase activity
EC81_RS09395	COG3119	arylsulfatase activity
EC81_RS09415	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EC81_RS09425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EC81_RS09445	COG1253	flavin adenine dinucleotide binding
EC81_RS09455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EC81_RS09465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC81_RS09505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EC81_RS09540	COG2030	dehydratase
EC81_RS09555	COG0110	maltose O-acetyltransferase activity
EC81_RS09570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC81_RS09590	COG1216	Glycosyl transferase, family 2
EC81_RS09600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS09615	COG4771	TonB-dependent receptor
EC81_RS09625	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EC81_RS09630	COG0563	adenylate kinase activity
EC81_RS09635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EC81_RS09640	COG1496	oxidoreductase activity
EC81_RS09660	COG2706	6-phosphogluconolactonase activity
EC81_RS09680	COG2207	Transcriptional regulator
EC81_RS09700	COG1288	antiporter activity
EC81_RS09735	COG0454	-acetyltransferase
EC81_RS09740	COG0564	pseudouridine synthase activity
EC81_RS09755	COG1501	Belongs to the glycosyl hydrolase 31 family
EC81_RS09775	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EC81_RS09785	COG3011	Protein conserved in bacteria
EC81_RS09800	COG0148	phosphopyruvate hydratase activity
EC81_RS09815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EC81_RS09820	COG1082	Xylose isomerase domain protein TIM barrel
EC81_RS09845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EC81_RS09850	COG0193	aminoacyl-tRNA hydrolase activity
EC81_RS09855	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EC81_RS09865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EC81_RS09870	COG1862	Preprotein translocase
EC81_RS09880	COG0237	dephospho-CoA kinase activity
EC81_RS09895	COG0542	response to heat
EC81_RS09905	COG0583	DNA-binding transcription factor activity
EC81_RS09910	COG2855	membrane
EC81_RS09925	COG1595	DNA-templated transcription, initiation
EC81_RS09940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EC81_RS09960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC81_RS09980	COG0443	Heat shock 70 kDa protein
EC81_RS10070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EC81_RS10075	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EC81_RS10080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC81_RS10100	COG1501	Belongs to the glycosyl hydrolase 31 family
EC81_RS10120	COG1629	transport
EC81_RS10120	COG4206	TonB-dependent receptor
EC81_RS10130	COG1408	metallophosphoesterase
EC81_RS10140	COG3634	alkyl hydroperoxide reductase activity
EC81_RS10175	COG1760	l-serine dehydratase
EC81_RS10180	COG0598	Magnesium transport protein CorA
EC81_RS10185	COG1193	negative regulation of DNA recombination
EC81_RS10195	COG4974	Belongs to the 'phage' integrase family
EC81_RS10350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC81_RS10350	COG0551	DNA topoisomerase type I activity
EC81_RS10355	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC81_RS10355	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC81_RS10490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EC81_RS10495	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC81_RS10500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EC81_RS10505	COG3189	MarR family transcriptional regulator
EC81_RS10510	COG2885	chlorophyll binding
EC81_RS10520	COG2217	Heavy metal translocating P-type atpase
EC81_RS10525	COG2855	membrane
EC81_RS10535	COG1629	transport
EC81_RS10535	COG4206	TonB-dependent receptor
EC81_RS10545	COG2207	Transcriptional regulator
EC81_RS10545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC81_RS10570	COG4651	solute:proton antiporter activity
EC81_RS10570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC81_RS10575	COG1280	lysine exporter protein (LysE YggA)
EC81_RS10590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EC81_RS10595	COG0561	phosphatase activity
EC81_RS10600	COG1169	isochorismate synthase
EC81_RS10605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EC81_RS10615	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC81_RS10620	COG4948	Mandelate Racemase Muconate Lactonizing
EC81_RS10635	COG1082	Xylose isomerase domain protein TIM barrel
EC81_RS10650	COG4771	TonB-dependent receptor
EC81_RS10680	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EC81_RS10685	COG0783	Belongs to the Dps family
EC81_RS10710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC81_RS10755	COG4804	nuclease activity
EC81_RS10790	COG0156	8-amino-7-oxononanoate synthase activity
EC81_RS10820	COG0542	response to heat
EC81_RS10975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EC81_RS10975	COG2755	lipolytic protein G-D-S-L family
EC81_RS11000	COG1253	flavin adenine dinucleotide binding
EC81_RS11005	COG0501	Belongs to the peptidase M48B family
EC81_RS11035	COG2873	o-acetylhomoserine
EC81_RS11055	COG1757	Na H antiporter
EC81_RS11070	COG2814	Major facilitator Superfamily
EC81_RS11075	COG4953	penicillin-binding protein 1C
EC81_RS11080	COG2373	Large extracellular alpha-helical protein
EC81_RS11090	COG1918	ferrous iron import across plasma membrane
EC81_RS11090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EC81_RS11315	COG0629	single-stranded DNA binding
EC81_RS11430	COG1193	negative regulation of DNA recombination
EC81_RS11455	COG3177	Filamentation induced by cAMP protein fic
EC81_RS11505	COG1086	Polysaccharide biosynthesis protein
EC81_RS11510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS11525	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS11535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC81_RS11565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC81_RS11570	COG0463	Glycosyl transferase, family 2
EC81_RS11570	COG1216	Glycosyl transferase, family 2
EC81_RS11580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS11600	COG0471	metal ion transport
EC81_RS11600	COG0490	domain, Protein
EC81_RS11615	COG0346	lactoylglutathione lyase activity
EC81_RS11630	COG0259	pyridoxamine-phosphate oxidase activity
EC81_RS11635	COG1741	Belongs to the pirin family
EC81_RS11655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC81_RS11680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EC81_RS11690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EC81_RS11705	COG1595	DNA-templated transcription, initiation
EC81_RS11730	COG0686	Belongs to the AlaDH PNT family
EC81_RS11750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC81_RS11795	COG0488	(ABC) transporter
EC81_RS11800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC81_RS11805	COG3059	membrane
EC81_RS11810	COG2207	Transcriptional regulator
EC81_RS11810	COG0662	Cupin 2, conserved barrel domain protein
EC81_RS11815	COG0295	cytidine deaminase activity
EC81_RS11820	COG1705	Flagellar rod assembly protein muramidase FlgJ
EC81_RS11820	COG1388	LysM domain
EC81_RS11835	COG0577	efflux transmembrane transporter activity
EC81_RS11845	COG0577	efflux transmembrane transporter activity
EC81_RS11855	COG0577	efflux transmembrane transporter activity
EC81_RS11865	COG1136	(ABC) transporter
EC81_RS11865	COG0577	efflux transmembrane transporter activity
EC81_RS11875	COG0662	Cupin 2, conserved barrel domain protein
EC81_RS11875	COG2207	Transcriptional regulator
EC81_RS11890	COG1136	(ABC) transporter
EC81_RS11895	COG1136	(ABC) transporter
EC81_RS11915	COG0784	Response regulator, receiver
EC81_RS11915	COG2205	protein histidine kinase activity
EC81_RS11925	COG2204	response regulator
EC81_RS11930	COG4191	Histidine kinase
EC81_RS11950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EC81_RS11960	COG0582	viral genome integration into host DNA
EC81_RS12010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC81_RS12015	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EC81_RS12025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC81_RS12040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS12045	COG2244	polysaccharide biosynthetic process
EC81_RS12055	COG0463	Glycosyl transferase, family 2
EC81_RS12060	COG0438	transferase activity, transferring glycosyl groups
EC81_RS12095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS12100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS12110	COG1396	sequence-specific DNA binding
EC81_RS12125	COG1530	ribonuclease E activity
EC81_RS12140	COG3119	arylsulfatase activity
EC81_RS12145	COG0629	single-stranded DNA binding
EC81_RS12210	COG4206	TonB-dependent receptor
EC81_RS12235	COG0745	RESPONSE REGULATOR receiver
EC81_RS12260	COG0488	(ABC) transporter
EC81_RS12275	COG5492	domain, Protein
EC81_RS12285	COG0436	Aminotransferase
EC81_RS12290	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC81_RS12295	COG1215	transferase activity, transferring glycosyl groups
EC81_RS12300	COG0628	permease
EC81_RS12310	COG2204	response regulator
EC81_RS12320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS12330	COG0577	efflux transmembrane transporter activity
EC81_RS12330	COG1136	(ABC) transporter
EC81_RS12335	COG1136	(ABC) transporter
EC81_RS12335	COG0577	efflux transmembrane transporter activity
EC81_RS12340	COG1252	NADH dehydrogenase
EC81_RS12370	COG4771	TonB-dependent receptor
EC81_RS12380	COG1620	l-lactate permease
EC81_RS12385	COG3047	cAMP biosynthetic process
EC81_RS12385	COG2885	chlorophyll binding
EC81_RS12395	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC81_RS12400	COG0439	Biotin carboxylase
EC81_RS12405	COG0511	ligase activity, forming carbon-carbon bonds
EC81_RS12410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EC81_RS12450	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC81_RS12455	COG0022	dehydrogenase e1 component
EC81_RS12460	COG0716	FMN binding
EC81_RS12465	COG2264	protein methyltransferase activity
EC81_RS12525	COG0590	tRNA wobble adenosine to inosine editing
EC81_RS12550	COG0673	inositol 2-dehydrogenase activity
EC81_RS12555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC81_RS12605	COG0698	ribose 5-phosphate isomerase
EC81_RS12610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC81_RS12615	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EC81_RS12630	COG1482	cell wall glycoprotein biosynthetic process
EC81_RS12650	COG0513	Belongs to the DEAD box helicase family
EC81_RS12655	COG4221	oxidoreductase activity
EC81_RS12665	COG3250	beta-galactosidase activity
EC81_RS12675	COG0471	metal ion transport
EC81_RS12675	COG3273	potassium ion transport
EC81_RS12680	COG0529	Catalyzes the synthesis of activated sulfate
EC81_RS12685	COG0175	sulfate reduction
EC81_RS12705	COG2885	chlorophyll binding
EC81_RS12725	COG4974	Belongs to the 'phage' integrase family
EC81_RS12750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EC81_RS12755	COG0242	peptide deformylase activity
EC81_RS12770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EC81_RS12775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EC81_RS12780	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EC81_RS12785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EC81_RS12795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EC81_RS12800	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EC81_RS12805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC81_RS12805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EC81_RS12805	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC81_RS12805	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC81_RS12815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EC81_RS12855	COG1940	carbohydrate kinase activity
EC81_RS12860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC81_RS12870	COG2271	Major facilitator Superfamily
EC81_RS12875	COG2731	YhcH YjgK YiaL family protein
EC81_RS12880	COG1629	transport
EC81_RS12885	COG0702	epimerase
EC81_RS12895	COG1629	transport
EC81_RS12900	COG0702	epimerase
EC81_RS12920	COG4771	TonB-dependent receptor
EC81_RS12925	COG0702	epimerase
EC81_RS12930	COG0702	epimerase
EC81_RS12935	COG4206	TonB-dependent receptor
EC81_RS12935	COG1629	transport
EC81_RS12955	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS12975	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS12985	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS12990	COG3537	Alpha-1,2-mannosidase
EC81_RS12995	COG3250	beta-galactosidase activity
EC81_RS13000	COG4771	TonB-dependent receptor
EC81_RS13005	COG0702	epimerase
EC81_RS13010	COG0484	heat shock protein binding
EC81_RS13015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EC81_RS13020	COG0488	(ABC) transporter
EC81_RS13025	COG1595	DNA-templated transcription, initiation
EC81_RS13080	COG2885	chlorophyll binding
EC81_RS13195	COG2183	response to ionizing radiation
EC81_RS13200	COG2205	protein histidine kinase activity
EC81_RS13200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC81_RS13205	COG0737	Belongs to the 5'-nucleotidase family
EC81_RS13210	COG1956	GAF domain-containing protein
EC81_RS13220	COG4771	TonB-dependent receptor
EC81_RS13245	COG0534	Mate efflux family protein
EC81_RS13260	COG4771	TonB-dependent receptor
EC81_RS13290	COG0534	Mate efflux family protein
EC81_RS13300	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EC81_RS13310	COG0318	PFAM AMP-dependent synthetase and ligase
EC81_RS13315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS13320	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EC81_RS13355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC81_RS13360	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EC81_RS13370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS13400	COG3754	Rhamnan synthesis protein F
EC81_RS13430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EC81_RS13445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS13450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS13470	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EC81_RS13475	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EC81_RS13480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EC81_RS13485	COG0363	glucosamine-6-phosphate deaminase activity
EC81_RS13515	COG1742	UPF0060 membrane protein
EC81_RS13605	COG3279	Response regulator of the LytR AlgR family
EC81_RS13615	COG1136	(ABC) transporter
EC81_RS13615	COG0577	efflux transmembrane transporter activity
EC81_RS13620	COG1136	(ABC) transporter
EC81_RS13625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS13660	COG3831	ATPase activity
EC81_RS13660	COG4884	unkown
EC81_RS13675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC81_RS13685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC81_RS13690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EC81_RS13695	COG3250	beta-galactosidase activity
EC81_RS13720	COG0501	Belongs to the peptidase M48B family
EC81_RS13725	COG1704	LemA family
EC81_RS13730	COG1595	DNA-templated transcription, initiation
EC81_RS13740	COG1629	transport
EC81_RS13740	COG4206	TonB-dependent receptor
EC81_RS13750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC81_RS13755	COG2885	chlorophyll binding
EC81_RS13755	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC81_RS13765	COG0697	spore germination
EC81_RS13795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC81_RS13800	COG0656	L-ascorbic acid biosynthetic process
EC81_RS13810	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EC81_RS13815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC81_RS13820	COG2814	Major facilitator Superfamily
EC81_RS13825	COG4771	TonB-dependent receptor
EC81_RS13830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC81_RS13835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC81_RS13920	COG1196	nuclear chromosome segregation
EC81_RS13960	COG3344	reverse transcriptase
EC81_RS13980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC81_RS13980	COG0551	DNA topoisomerase type I activity
EC81_RS13990	COG0156	8-amino-7-oxononanoate synthase activity
EC81_RS14015	COG0542	response to heat
EC81_RS14030	COG1705	Flagellar rod assembly protein muramidase FlgJ
EC81_RS14030	COG1388	LysM domain
EC81_RS14280	COG4974	Belongs to the 'phage' integrase family
EC81_RS14290	COG0488	(ABC) transporter
EC81_RS14310	COG0784	Response regulator, receiver
EC81_RS14310	COG2205	protein histidine kinase activity
EC81_RS14330	COG0438	transferase activity, transferring glycosyl groups
EC81_RS14340	COG2244	polysaccharide biosynthetic process
EC81_RS14345	COG1442	glycosyl transferase family 8
EC81_RS14345	COG1216	Glycosyl transferase, family 2
EC81_RS14390	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC81_RS14405	COG1215	transferase activity, transferring glycosyl groups
EC81_RS14435	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC81_RS14440	COG1805	sodium ion transport
EC81_RS14445	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC81_RS14475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EC81_RS14480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC81_RS14490	COG0545	Peptidyl-prolyl cis-trans isomerase
EC81_RS14495	COG1739	Uncharacterized protein family UPF0029
EC81_RS14535	COG0110	maltose O-acetyltransferase activity
EC81_RS14550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC81_RS14550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC81_RS14555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC81_RS14585	COG2217	Heavy metal translocating P-type atpase
EC81_RS14595	COG0321	lipoyl(octanoyl) transferase activity
EC81_RS14615	COG3852	Histidine kinase
EC81_RS14620	COG2204	response regulator
EC81_RS14635	COG1136	(ABC) transporter
EC81_RS14650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC81_RS14660	COG1755	Isoprenylcysteine carboxyl methyltransferase
EC81_RS14670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EC81_RS14685	COG1678	Uncharacterized ACR, COG1678
EC81_RS14900	COG4771	TonB-dependent receptor
EC81_RS14910	COG3119	arylsulfatase activity
EC81_RS14915	COG3250	beta-galactosidase activity
EC81_RS14930	COG0681	Belongs to the peptidase S26 family
EC81_RS14935	COG0697	spore germination
EC81_RS14965	COG3969	phosphoadenosine phosphosulfate
EC81_RS14970	COG1475	DNA binding
EC81_RS15015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS15020	COG0745	RESPONSE REGULATOR receiver
EC81_RS15035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS15045	COG1629	transport
EC81_RS15045	COG4206	TonB-dependent receptor
EC81_RS15055	COG4974	Belongs to the 'phage' integrase family
EC81_RS15165	COG2207	Transcriptional regulator
EC81_RS15165	COG1917	Cupin 2, conserved barrel domain protein
EC81_RS15170	COG0110	maltose O-acetyltransferase activity
EC81_RS15185	COG1846	Transcriptional regulator
EC81_RS15210	COG1022	Amp-dependent synthetase and ligase
EC81_RS15215	COG3263	regulation of cellular component size
EC81_RS15225	COG1151	hydroxylamine reductase activity
EC81_RS15240	COG2204	response regulator
EC81_RS15260	COG1136	(ABC) transporter
EC81_RS15260	COG0577	efflux transmembrane transporter activity
EC81_RS15265	COG1136	(ABC) transporter
EC81_RS15265	COG0577	efflux transmembrane transporter activity
EC81_RS15275	COG1136	(ABC) transporter
EC81_RS15285	COG0534	Mate efflux family protein
EC81_RS15290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC81_RS15300	COG0167	dihydroorotate dehydrogenase activity
EC81_RS15305	COG2755	lipolytic protein G-D-S-L family
EC81_RS15305	COG0657	acetylesterase activity
EC81_RS15310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EC81_RS15325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC81_RS15345	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EC81_RS15355	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EC81_RS15365	COG0356	it plays a direct role in the translocation of protons across the membrane
EC81_RS15370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC81_RS15375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EC81_RS15380	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC81_RS15385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EC81_RS15390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EC81_RS15395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC81_RS15400	COG3118	belongs to the thioredoxin family
EC81_RS15420	COG0745	RESPONSE REGULATOR receiver
EC81_RS15425	COG5002	protein histidine kinase activity
EC81_RS15460	COG1120	ATPase activity
EC81_RS15465	COG1091	dTDP-4-dehydrorhamnose reductase activity
EC81_RS15505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC81_RS15510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EC81_RS15525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EC81_RS15530	COG1064	alcohol dehydrogenase
EC81_RS15565	COG2202	Pas domain
EC81_RS15565	COG2205	protein histidine kinase activity
EC81_RS15570	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EC81_RS15580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EC81_RS15595	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EC81_RS15600	COG0540	Belongs to the ATCase OTCase family
EC81_RS15610	COG2431	L-lysine efflux transmembrane transporter activity
EC81_RS15640	COG2837	iron assimilation
EC81_RS15650	COG4206	TonB-dependent receptor
EC81_RS15650	COG1629	transport
EC81_RS15670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EC81_RS15680	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EC81_RS15695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EC81_RS15700	COG2205	protein histidine kinase activity
EC81_RS15720	COG2135	peptidase activity
EC81_RS15730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC81_RS15735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC81_RS15760	COG0673	inositol 2-dehydrogenase activity
EC81_RS15775	COG2223	nitrite transmembrane transporter activity
EC81_RS15795	COG0671	phosphoesterase, PA-phosphatase related
EC81_RS15815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC81_RS15820	COG0045	succinate-CoA ligase (ADP-forming) activity
EC81_RS15825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC81_RS15830	COG0351	phosphomethylpyrimidine kinase
EC81_RS15850	COG0477	Major facilitator Superfamily
EC81_RS15850	COG2814	Major facilitator Superfamily
EC81_RS15865	COG3153	acetyltransferase
EC81_RS15865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC81_RS15870	COG0450	alkyl hydroperoxide reductase
EC81_RS15875	COG0724	RNA recognition motif
EC81_RS15880	COG1858	cytochrome C peroxidase
EC81_RS15885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC81_RS15910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EC81_RS15920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EC81_RS15935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC81_RS15985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC81_RS15995	COG1904	glucuronate isomerase
EC81_RS16025	COG0513	Belongs to the DEAD box helicase family
EC81_RS16030	COG0560	Phosphoserine phosphatase
EC81_RS16030	COG3830	Belongs to the UPF0237 family
EC81_RS16055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EC81_RS16060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EC81_RS16360	COG4974	Belongs to the 'phage' integrase family
EC81_RS16515	COG2204	response regulator
EC81_RS16565	COG0577	efflux transmembrane transporter activity
EC81_RS16565	COG1136	(ABC) transporter
EC81_RS16575	COG0156	8-amino-7-oxononanoate synthase activity
EC81_RS16580	COG1597	lipid kinase activity
EC81_RS16585	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EC81_RS16610	COG0577	efflux transmembrane transporter activity
EC81_RS16610	COG1136	(ABC) transporter
EC81_RS16635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EC81_RS16665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC81_RS16685	COG0543	2 iron, 2 sulfur cluster binding
EC81_RS16690	COG0167	dihydroorotate dehydrogenase activity
EC81_RS16695	COG0336	Belongs to the RNA methyltransferase TrmD family
EC81_RS16700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC81_RS16705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC81_RS16730	COG0326	Molecular chaperone. Has ATPase activity
EC81_RS16735	COG0542	response to heat
EC81_RS16780	COG2304	oxidoreductase activity
EC81_RS16795	COG0714	Associated with various cellular activities
EC81_RS16800	COG1652	LysM domain
EC81_RS16810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC81_RS16815	COG0552	protein localization to endoplasmic reticulum
EC81_RS16825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EC81_RS16830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EC81_RS16835	COG1058	Belongs to the CinA family
EC81_RS16835	COG1546	Belongs to the CinA family
EC81_RS16840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EC81_RS16855	COG0442	prolyl-tRNA aminoacylation
EC81_RS16870	COG4946	Tricorn protease homolog
EC81_RS16870	COG0793	Belongs to the peptidase S41A family
EC81_RS17100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC81_RS17145	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EC81_RS17160	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EC81_RS17170	COG1492	cobalamin metabolic process
EC81_RS17205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS17225	COG2096	Adenosyltransferase
EC81_RS17230	COG1797	cobyrinic acid a,c-diamide synthase activity
EC81_RS17245	COG2966	Psort location CytoplasmicMembrane, score
EC81_RS17265	COG4771	TonB-dependent receptor
EC81_RS17275	COG4774	siderophore transport
EC81_RS17300	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EC81_RS17405	COG0305	Participates in initiation and elongation during chromosome replication
EC81_RS17415	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC81_RS17470	COG0352	thiamine-phosphate diphosphorylase activity
EC81_RS17475	COG2022	thiamine diphosphate biosynthetic process
EC81_RS17480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EC81_RS17495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC81_RS17500	COG0352	thiamine-phosphate diphosphorylase activity
EC81_RS17515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC81_RS17515	COG0574	Belongs to the PEP-utilizing enzyme family
EC81_RS17520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EC81_RS17525	COG0564	pseudouridine synthase activity
EC81_RS17540	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EC81_RS17545	COG1518	maintenance of DNA repeat elements
EC81_RS17675	COG4771	TonB-dependent receptor
EC81_RS17680	COG0702	epimerase
EC81_RS17700	COG3392	D12 class N6 adenine-specific DNA methyltransferase
EC81_RS17710	COG1192	Involved in chromosome partitioning
EC81_RS17740	COG0741	lytic transglycosylase activity
EC81_RS17740	COG0739	heme binding
EC81_RS17740	COG1196	nuclear chromosome segregation
EC81_RS17920	COG0024	Methionine aminopeptidase
EC81_RS17945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EC81_RS17955	COG0481	GTPase activity
EC81_RS17975	COG0708	Exodeoxyribonuclease III
EC81_RS17980	COG1914	H( )-stimulated, divalent metal cation uptake system
EC81_RS17995	COG0217	transcriptional regulatory protein
EC81_RS18000	COG0072	phenylalanine-tRNA ligase activity
EC81_RS18000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC81_RS18005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS18010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS18015	COG1216	Glycosyl transferase, family 2
EC81_RS18105	COG0305	Participates in initiation and elongation during chromosome replication
EC81_RS18110	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EC81_RS18125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EC81_RS18130	COG4657	Part of a membrane complex involved in electron transport
EC81_RS18135	COG4660	Part of a membrane complex involved in electron transport
EC81_RS18140	COG4659	FMN binding
EC81_RS18145	COG4658	electron transport chain
EC81_RS18150	COG4656	Part of a membrane complex involved in electron transport
EC81_RS18175	COG0504	CTP synthase activity
EC81_RS18185	COG0534	Mate efflux family protein
EC81_RS18190	COG1506	peptidase
EC81_RS18190	COG0823	Involved in the tonB-independent uptake of proteins
EC81_RS18205	COG0110	maltose O-acetyltransferase activity
EC81_RS18215	COG1695	Transcriptional regulator
EC81_RS18230	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC81_RS18240	COG3942	CHAP domain
EC81_RS18240	COG1388	LysM domain
EC81_RS18270	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EC81_RS18290	COG0556	nucleotide-excision repair
EC81_RS18295	COG2949	membrane
EC81_RS18315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EC81_RS18330	COG2205	protein histidine kinase activity
EC81_RS18330	COG0784	Response regulator, receiver
EC81_RS18335	COG0842	Transport permease protein
EC81_RS18340	COG0842	Transport permease protein
EC81_RS18345	COG1131	(ABC) transporter
EC81_RS18380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC81_RS18385	COG0505	Belongs to the CarA family
EC81_RS18400	COG0067	glutamate synthase
EC81_RS18400	COG0070	glutamate synthase
EC81_RS18400	COG0069	glutamate synthase activity
EC81_RS18410	COG0367	asparagine synthase
EC81_RS18440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EC81_RS18450	COG1979	alcohol dehydrogenase
EC81_RS18460	COG0133	tryptophan synthase activity
EC81_RS18465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC81_RS18480	COG0134	indole-3-glycerol-phosphate synthase activity
EC81_RS18485	COG0135	phosphoribosylanthranilate isomerase activity
EC81_RS18490	COG0159	tryptophan synthase activity
EC81_RS18495	COG0252	asparaginase activity
EC81_RS18505	COG0745	RESPONSE REGULATOR receiver
EC81_RS18505	COG3292	Two component regulator propeller
EC81_RS18505	COG2205	protein histidine kinase activity
EC81_RS18510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC81_RS18520	COG0110	maltose O-acetyltransferase activity
EC81_RS18525	COG2197	response regulator
EC81_RS18535	COG0138	bifunctional purine biosynthesis protein purh
EC81_RS18540	COG0716	FMN binding
EC81_RS18565	COG1858	cytochrome C peroxidase
EC81_RS18575	COG4771	TonB-dependent receptor
EC81_RS18590	COG1132	(ABC) transporter
EC81_RS18605	COG2814	Major facilitator Superfamily
EC81_RS18610	COG1566	PFAM secretion protein HlyD family protein
EC81_RS18660	COG4771	TonB-dependent receptor
EC81_RS18690	COG3610	response to peptide
EC81_RS18705	COG1609	Transcriptional regulator
EC81_RS18715	COG1733	regulation of RNA biosynthetic process
EC81_RS18725	COG5002	protein histidine kinase activity
EC81_RS18725	COG2198	Histidine kinase
EC81_RS18725	COG0784	Response regulator, receiver
EC81_RS18735	COG5002	protein histidine kinase activity
EC81_RS18740	COG0745	RESPONSE REGULATOR receiver
EC81_RS18760	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EC81_RS18765	COG1690	Belongs to the RtcB family
EC81_RS18785	COG0228	four-way junction DNA binding
EC81_RS18800	COG0724	RNA recognition motif
EC81_RS18810	COG1177	transmembrane transport
EC81_RS18815	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC81_RS18825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC81_RS18840	COG0058	SHG alpha-glucan phosphorylase activity
EC81_RS18850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC81_RS18870	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EC81_RS18930	COG0745	RESPONSE REGULATOR receiver
EC81_RS18935	COG5002	protein histidine kinase activity
EC81_RS18960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC81_RS18970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC81_RS18980	COG4948	Mandelate Racemase Muconate Lactonizing
EC81_RS18995	COG1295	ribonuclease BN
EC81_RS19000	COG0778	Nitroreductase
EC81_RS19005	COG0307	riboflavin synthase, alpha
EC81_RS19010	COG0704	Plays a role in the regulation of phosphate uptake
EC81_RS19015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC81_RS19020	COG0581	inorganic phosphate transmembrane transporter activity
EC81_RS19025	COG0573	inorganic phosphate transmembrane transporter activity
EC81_RS19035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC81_RS19060	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EC81_RS19095	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC81_RS19125	COG3594	Acyltransferase
EC81_RS19145	COG1216	Glycosyl transferase, family 2
EC81_RS19145	COG0463	Glycosyl transferase, family 2
EC81_RS19215	COG0438	transferase activity, transferring glycosyl groups
EC81_RS19220	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EC81_RS19265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EC81_RS19265	COG0662	Cupin 2, conserved barrel domain protein
EC81_RS19270	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EC81_RS19290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC81_RS19295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC81_RS19310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EC81_RS19315	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS19325	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS19340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC81_RS19360	COG1216	Glycosyl transferase, family 2
EC81_RS19385	COG2244	polysaccharide biosynthetic process
EC81_RS19400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC81_RS19465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EC81_RS19470	COG0167	dihydroorotate dehydrogenase activity
EC81_RS19535	COG5002	protein histidine kinase activity
EC81_RS19550	COG2172	sigma factor antagonist activity
EC81_RS19575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EC81_RS19600	COG0497	DNA recombination
EC81_RS19610	COG5002	protein histidine kinase activity
EC81_RS19610	COG2176	DNA-directed DNA polymerase activity
EC81_RS19615	COG0592	DNA-directed DNA polymerase activity
EC81_RS19630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC81_RS19630	COG0321	lipoyl(octanoyl) transferase activity
EC81_RS19645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS19655	COG0156	8-amino-7-oxononanoate synthase activity
EC81_RS19760	COG0019	diaminopimelate decarboxylase activity
EC81_RS19765	COG0527	aspartate kinase activity
EC81_RS19770	COG2884	Cell division ATP-binding protein ftsE
EC81_RS19775	COG0140	phosphoribosyl-ATP diphosphatase activity
EC81_RS19775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EC81_RS19780	COG0107	imidazoleglycerol-phosphate synthase activity
EC81_RS19785	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EC81_RS19845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC81_RS19850	COG4974	Belongs to the 'phage' integrase family
EC81_RS19970	COG0551	DNA topoisomerase type I activity
EC81_RS19970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC81_RS19995	COG3586	endonuclease activity
EC81_RS20035	COG1917	Cupin 2, conserved barrel domain protein
EC81_RS20035	COG4977	sequence-specific DNA binding
EC81_RS20045	COG0693	protein deglycase activity
EC81_RS20060	COG0494	nUDIX hydrolase
EC81_RS20075	COG3326	Membrane
EC81_RS20180	COG0561	phosphatase activity
EC81_RS20185	COG1629	transport
EC81_RS20185	COG4206	TonB-dependent receptor
EC81_RS20245	COG0363	glucosamine-6-phosphate deaminase activity
EC81_RS20285	COG1032	radical SAM domain protein
EC81_RS20290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EC81_RS20295	COG0463	Glycosyl transferase, family 2
EC81_RS20300	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EC81_RS20305	COG0646	methionine synthase
EC81_RS20305	COG1410	methionine synthase
EC81_RS20345	COG1408	metallophosphoesterase
EC81_RS20350	COG1132	(ABC) transporter
EC81_RS20355	COG1132	(ABC) transporter
EC81_RS20365	COG0420	3'-5' exonuclease activity
EC81_RS20400	COG0681	Belongs to the peptidase S26 family
EC81_RS20510	COG0641	radical SAM
EC81_RS20515	COG3591	Belongs to the peptidase S1B family
EC81_RS20520	COG3591	Belongs to the peptidase S1B family
EC81_RS20550	COG1592	Rubrerythrin
EC81_RS20550	COG1773	rubredoxin
EC81_RS20560	COG3152	Membrane
EC81_RS20565	COG0339	signal peptide processing
EC81_RS20570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC81_RS20570	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EC81_RS20580	COG1629	transport
EC81_RS20580	COG4206	TonB-dependent receptor
EC81_RS20595	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC81_RS20595	COG0131	Imidazoleglycerol-phosphate dehydratase
EC81_RS20605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC81_RS20610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EC81_RS20620	COG1741	Belongs to the pirin family
EC81_RS20625	COG4232	protein-disulfide reductase activity
EC81_RS20635	COG0572	uridine kinase
EC81_RS20640	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC81_RS20645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC81_RS20655	COG0646	methionine synthase
EC81_RS20655	COG1410	methionine synthase
EC81_RS20660	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EC81_RS20695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC81_RS20705	COG1295	ribonuclease BN
EC81_RS20715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS20720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC81_RS20730	COG0438	transferase activity, transferring glycosyl groups
EC81_RS20730	COG0297	glycogen (starch) synthase activity
EC81_RS20740	COG1216	Glycosyl transferase, family 2
EC81_RS20740	COG1442	glycosyl transferase family 8
EC81_RS20745	COG1045	serine acetyltransferase
EC81_RS20750	COG1442	glycosyl transferase family 8
EC81_RS20750	COG1216	Glycosyl transferase, family 2
EC81_RS20755	COG1216	Glycosyl transferase, family 2
EC81_RS20755	COG1442	glycosyl transferase family 8
EC81_RS20765	COG1216	Glycosyl transferase, family 2
EC81_RS20825	COG3437	response regulator, receiver
EC81_RS20825	COG2205	protein histidine kinase activity
EC81_RS20825	COG4999	Histidine kinase
EC81_RS20825	COG3850	Histidine kinase
EC81_RS20830	COG2205	protein histidine kinase activity
EC81_RS20830	COG2202	Pas domain
EC81_RS20835	COG0534	Mate efflux family protein
EC81_RS20840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EC81_RS20845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC81_RS20850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EC81_RS20855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC81_RS20925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EC81_RS20965	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC81_RS20975	COG0668	transmembrane transport
EC81_RS20980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC81_RS20990	COG3250	beta-galactosidase activity
EC81_RS20995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS21000	COG3119	arylsulfatase activity
EC81_RS21005	COG3119	arylsulfatase activity
EC81_RS21010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS21015	COG0745	RESPONSE REGULATOR receiver
EC81_RS21015	COG2205	protein histidine kinase activity
EC81_RS21015	COG3292	Two component regulator propeller
EC81_RS21020	COG1830	Aldolase
EC81_RS21025	COG0588	phosphoglycerate mutase activity
EC81_RS21030	COG1119	ATPase activity
EC81_RS21035	COG3119	arylsulfatase activity
EC81_RS21040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS21050	COG1629	transport
EC81_RS21050	COG4206	TonB-dependent receptor
EC81_RS21065	COG1523	belongs to the glycosyl hydrolase 13 family
EC81_RS21070	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EC81_RS21090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EC81_RS21105	COG0126	phosphoglycerate kinase activity
EC81_RS21120	COG2311	Membrane
EC81_RS21175	COG0424	maF-like protein
EC81_RS21180	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EC81_RS21195	COG0778	Nitroreductase
EC81_RS21200	COG0288	reversible hydration of carbon dioxide
EC81_RS21215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC81_RS21225	COG5016	pyruvate
EC81_RS21225	COG0511	ligase activity, forming carbon-carbon bonds
EC81_RS21230	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EC81_RS21245	COG0366	Alpha amylase catalytic
EC81_RS21265	COG0191	fructose-bisphosphate aldolase activity
EC81_RS21275	COG0254	rRNA binding
EC81_RS21280	COG5002	protein histidine kinase activity
EC81_RS21300	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC81_RS21305	COG4206	TonB-dependent receptor
EC81_RS21305	COG1629	transport
EC81_RS21310	COG1609	Transcriptional regulator
EC81_RS21380	COG1554	hydrolase, family 65, central catalytic
EC81_RS21385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS21410	COG0047	phosphoribosylformylglycinamidine synthase activity
EC81_RS21410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EC81_RS21415	COG3292	Two component regulator propeller
EC81_RS21415	COG0745	RESPONSE REGULATOR receiver
EC81_RS21415	COG2205	protein histidine kinase activity
EC81_RS21430	COG1649	PFAM Uncharacterised BCR, COG1649
EC81_RS21450	COG1966	Carbon starvation protein
EC81_RS21455	COG1649	PFAM Uncharacterised BCR, COG1649
EC81_RS21460	COG3437	response regulator, receiver
EC81_RS21460	COG3850	Histidine kinase
EC81_RS21460	COG2205	protein histidine kinase activity
EC81_RS21460	COG4999	Histidine kinase
EC81_RS21510	COG2113	Glycine betaine
EC81_RS21515	COG4176	ABC-type proline glycine betaine transport system permease component
EC81_RS21530	COG0745	RESPONSE REGULATOR receiver
EC81_RS21530	COG3292	Two component regulator propeller
EC81_RS21530	COG2205	protein histidine kinase activity
EC81_RS21535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EC81_RS21535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC81_RS21545	COG1621	beta-fructofuranosidase activity
EC81_RS21575	COG0420	3'-5' exonuclease activity
EC81_RS21580	COG4804	nuclease activity
EC81_RS21620	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC81_RS21625	COG0475	glutathione-regulated potassium exporter activity
EC81_RS21650	COG3015	lipoprotein NlpE involved in copper resistance
EC81_RS21660	COG3279	Response regulator of the LytR AlgR family
EC81_RS21675	COG4948	Mandelate Racemase Muconate Lactonizing
EC81_RS21680	COG4206	TonB-dependent receptor
EC81_RS21680	COG1629	transport
EC81_RS21685	COG0702	epimerase
EC81_RS21705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EC81_RS21725	COG0484	heat shock protein binding
EC81_RS21730	COG2205	protein histidine kinase activity
EC81_RS21730	COG0784	Response regulator, receiver
EC81_RS21735	COG2194	sulfuric ester hydrolase activity
EC81_RS21785	COG0028	Belongs to the TPP enzyme family
EC81_RS21800	COG0459	protein refolding
EC81_RS21805	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EC81_RS21845	COG2326	polyphosphate kinase activity
EC81_RS21895	COG3537	Alpha-1,2-mannosidase
EC81_RS21900	COG0823	Involved in the tonB-independent uptake of proteins
EC81_RS21900	COG1506	peptidase
EC81_RS21930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EC81_RS21965	COG0514	ATP-dependent DNA helicase (RecQ)
EC81_RS21980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC81_RS21990	COG0671	phosphoesterase, PA-phosphatase related
EC81_RS21995	COG0702	epimerase
EC81_RS22000	COG4206	TonB-dependent receptor
EC81_RS22000	COG1629	transport
EC81_RS22030	COG0463	Glycosyl transferase, family 2
EC81_RS22045	COG0066	3-isopropylmalate dehydratase activity
EC81_RS22050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC81_RS22055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC81_RS22110	COG0616	signal peptide processing
EC81_RS22120	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EC81_RS22125	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EC81_RS22165	COG1917	Cupin 2, conserved barrel domain protein
EC81_RS22165	COG2207	Transcriptional regulator
EC81_RS22175	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS22190	COG0463	Glycosyl transferase, family 2
EC81_RS22205	COG1971	Probably functions as a manganese efflux pump
EC81_RS22210	COG1477	protein flavinylation
EC81_RS22220	COG0037	tRNA processing
EC81_RS22235	COG4864	UPF0365 protein
EC81_RS22245	COG2176	DNA-directed DNA polymerase activity
EC81_RS22250	COG2910	NAD(P)H-binding
EC81_RS22255	COG0784	Response regulator, receiver
EC81_RS22255	COG2198	Histidine kinase
EC81_RS22255	COG5002	protein histidine kinase activity
EC81_RS22260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EC81_RS22295	COG0110	maltose O-acetyltransferase activity
EC81_RS22330	COG1910	domain protein
EC81_RS22420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EC81_RS22430	COG0456	acetyltransferase
EC81_RS22460	COG1028	Short-chain dehydrogenase reductase Sdr
EC81_RS22475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EC81_RS22480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC81_RS22485	COG4651	solute:proton antiporter activity
EC81_RS22485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC81_RS22490	COG0439	Biotin carboxylase
EC81_RS22495	COG0511	ligase activity, forming carbon-carbon bonds
EC81_RS22500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC81_RS22505	COG1917	Cupin 2, conserved barrel domain protein
EC81_RS22505	COG4977	sequence-specific DNA binding
EC81_RS22515	COG1335	isochorismatase
EC81_RS22525	COG2205	protein histidine kinase activity
EC81_RS22525	COG0784	Response regulator, receiver
EC81_RS22525	COG5002	protein histidine kinase activity
EC81_RS22530	COG2207	Transcriptional regulator
EC81_RS22535	COG0517	IMP dehydrogenase activity
EC81_RS22535	COG0516	GMP reductase activity
EC81_RS22555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC81_RS22595	COG2873	o-acetylhomoserine
EC81_RS22650	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC81_RS22795	COG2076	Multidrug Resistance protein
EC81_RS22835	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC81_RS22845	COG0741	lytic transglycosylase activity
EC81_RS22845	COG1388	LysM domain
EC81_RS22850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC81_RS22855	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC81_RS22855	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC81_RS22865	COG1285	pathogenesis
EC81_RS22885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC81_RS22885	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC81_RS22900	COG1115	amino acid carrier protein
EC81_RS22910	COG1509	lysine 2,3-aminomutase activity
EC81_RS22920	COG2233	PERMEase
EC81_RS22935	COG1393	Belongs to the ArsC family
EC81_RS22945	COG1629	transport
EC81_RS22955	COG2304	oxidoreductase activity
EC81_RS22965	COG0351	phosphomethylpyrimidine kinase
EC81_RS22975	COG1139	Iron-sulfur cluster binding protein
EC81_RS22980	COG0247	lactate metabolic process
EC81_RS22985	COG0602	queuosine metabolic process
EC81_RS22995	COG2832	Protein of unknown function (DUF454)
EC81_RS23000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC81_RS23015	COG3142	Participates in the control of copper homeostasis
EC81_RS23020	COG1418	mRNA catabolic process
EC81_RS23045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC81_RS23060	COG4771	TonB-dependent receptor
EC81_RS23100	COG3340	Belongs to the peptidase S51 family
EC81_RS23105	COG2378	regulation of single-species biofilm formation
EC81_RS23160	COG1505	serine-type exopeptidase activity
EC81_RS23190	COG0517	IMP dehydrogenase activity
EC81_RS23190	COG0617	tRNA 3'-terminal CCA addition
EC81_RS23190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EC81_RS23200	COG4206	TonB-dependent receptor
EC81_RS23200	COG1629	transport
EC81_RS23215	COG0612	Peptidase, M16
EC81_RS23225	COG1278	Cold shock
EC81_RS23245	COG0438	transferase activity, transferring glycosyl groups
EC81_RS23270	COG1216	Glycosyl transferase, family 2
EC81_RS23280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EC81_RS23290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC81_RS23370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EC81_RS23390	COG0632	four-way junction helicase activity
EC81_RS23395	COG0673	inositol 2-dehydrogenase activity
EC81_RS23400	COG1272	protein, Hemolysin III
EC81_RS23405	COG1328	CTP reductase activity
EC81_RS23415	COG2814	Major facilitator Superfamily
EC81_RS23425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC81_RS23435	COG0750	zinc metalloprotease
EC81_RS23440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EC81_RS23450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EC81_RS23455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EC81_RS23465	COG1214	PFAM Peptidase M22, glycoprotease
EC81_RS23470	COG2205	protein histidine kinase activity
EC81_RS23470	COG2198	Histidine kinase
EC81_RS23470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC81_RS23470	COG0784	Response regulator, receiver
EC81_RS23490	COG0194	GDP metabolic process
EC81_RS23495	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EC81_RS23500	COG1408	metallophosphoesterase
EC81_RS23505	COG1575	Belongs to the MenA family. Type 1 subfamily
EC81_RS23510	COG1088	dTDP-glucose 4,6-dehydratase activity
EC81_RS23515	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC81_RS23525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EC81_RS23540	COG2204	response regulator
EC81_RS23545	COG0488	(ABC) transporter
EC81_RS23580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EC81_RS23580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EC81_RS23605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC81_RS23610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EC81_RS23620	COG1522	sequence-specific DNA binding
EC81_RS23645	COG0811	peptide transport
EC81_RS23655	COG0084	hydrolase, TatD family'
EC81_RS23670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EC81_RS23675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EC81_RS23680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EC81_RS23685	COG0205	6-phosphofructokinase activity
EC81_RS23705	COG0372	Belongs to the citrate synthase family
EC81_RS23710	COG0538	isocitrate dehydrogenase activity
EC81_RS23720	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC81_RS23740	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EC81_RS23765	COG0129	dihydroxy-acid dehydratase activity
EC81_RS23785	COG2885	chlorophyll binding
EC81_RS23805	COG3681	Belongs to the UPF0597 family
EC81_RS23840	COG3119	arylsulfatase activity
EC81_RS23850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EC81_RS23860	COG0702	epimerase
EC81_RS23865	COG4771	TonB-dependent receptor
EC81_RS23940	COG0535	radical SAM domain protein
EC81_RS23955	COG4372	Transposase
EC81_RS23960	COG2433	Pfam Transposase IS66
EC81_RS23970	COG0702	epimerase
EC81_RS23975	COG1629	transport
EC81_RS23975	COG4206	TonB-dependent receptor
EC81_RS23995	COG4771	TonB-dependent receptor
EC81_RS24025	COG1012	belongs to the aldehyde dehydrogenase family
EC81_RS24050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC81_RS24050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC81_RS24055	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC81_RS24080	COG0534	Mate efflux family protein
EC81_RS24110	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC81_RS24120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EC81_RS24125	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EC81_RS24130	COG0166	Belongs to the GPI family
EC81_RS24140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC81_RS24150	COG2502	aspartate--ammonia ligase
EC81_RS24155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EC81_RS24170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC81_RS24195	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC81_RS24205	COG1629	transport
EC81_RS24235	COG3344	reverse transcriptase
EC81_RS24280	COG1192	Involved in chromosome partitioning
EC81_RS24285	COG3177	Filamentation induced by cAMP protein fic
EC81_RS24300	COG4974	Belongs to the 'phage' integrase family
EC81_RS24395	COG0739	heme binding
EC81_RS24395	COG1196	nuclear chromosome segregation
EC81_RS24395	COG0741	lytic transglycosylase activity
EC81_RS24590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EC81_RS24640	COG2337	Toxic component of a toxin-antitoxin (TA) module