locus-tag	class	description
EC80_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EC80_RS00020	COG1640	4-alpha-glucanotransferase
EC80_RS00030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EC80_RS00035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC80_RS00060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC80_RS00065	COG1022	Amp-dependent synthetase and ligase
EC80_RS00080	COG0359	binds to the 23S rRNA
EC80_RS00085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EC80_RS00090	COG0360	Binds together with S18 to 16S ribosomal RNA
EC80_RS00110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC80_RS00135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC80_RS00155	COG4771	TonB-dependent receptor
EC80_RS00170	COG2431	L-lysine efflux transmembrane transporter activity
EC80_RS00205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EC80_RS00210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EC80_RS00215	COG0386	Belongs to the glutathione peroxidase family
EC80_RS00235	COG3275	phosphorelay sensor kinase activity
EC80_RS00240	COG3279	Response regulator of the LytR AlgR family
EC80_RS00250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EC80_RS00260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EC80_RS00275	COG3250	beta-galactosidase activity
EC80_RS00280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC80_RS00290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EC80_RS00295	COG0658	competence protein
EC80_RS00300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EC80_RS00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EC80_RS00315	COG0009	L-threonylcarbamoyladenylate synthase
EC80_RS00345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS00350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS00360	COG1216	Glycosyl transferase, family 2
EC80_RS00370	COG1215	transferase activity, transferring glycosyl groups
EC80_RS00380	COG0110	maltose O-acetyltransferase activity
EC80_RS00410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EC80_RS00415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC80_RS00455	COG0519	Catalyzes the synthesis of GMP from XMP
EC80_RS00465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EC80_RS00465	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EC80_RS00470	COG0514	ATP-dependent DNA helicase (RecQ)
EC80_RS00480	COG2271	Major facilitator Superfamily
EC80_RS00495	COG0702	epimerase
EC80_RS00500	COG4771	TonB-dependent receptor
EC80_RS00505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC80_RS00510	COG2186	Transcriptional regulator
EC80_RS00525	COG0436	Aminotransferase
EC80_RS00530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EC80_RS00545	COG0358	DNA primase activity
EC80_RS00550	COG3119	arylsulfatase activity
EC80_RS00555	COG0702	epimerase
EC80_RS00560	COG4206	TonB-dependent receptor
EC80_RS00560	COG1629	transport
EC80_RS00575	COG0302	gtp cyclohydrolase
EC80_RS00585	COG0149	triose-phosphate isomerase activity
EC80_RS00600	COG0739	heme binding
EC80_RS00605	COG0105	UTP biosynthetic process
EC80_RS00610	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EC80_RS00635	COG0811	peptide transport
EC80_RS00645	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EC80_RS00685	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EC80_RS00690	COG0470	DNA polymerase III
EC80_RS00695	COG1774	PSP1 C-terminal conserved region
EC80_RS00705	COG0772	Belongs to the SEDS family
EC80_RS00720	COG1792	Involved in formation and maintenance of cell shape
EC80_RS00730	COG0138	bifunctional purine biosynthesis protein purh
EC80_RS00735	COG3590	peptidase
EC80_RS00740	COG0488	(ABC) transporter
EC80_RS00770	COG0784	Response regulator, receiver
EC80_RS00770	COG2205	protein histidine kinase activity
EC80_RS00775	COG0534	Mate efflux family protein
EC80_RS00780	COG0612	Peptidase, M16
EC80_RS00785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EC80_RS00800	COG0564	pseudouridine synthase activity
EC80_RS00855	COG1131	(ABC) transporter
EC80_RS00935	COG4771	TonB-dependent receptor
EC80_RS00955	COG3969	phosphoadenosine phosphosulfate
EC80_RS00960	COG1475	DNA binding
EC80_RS01050	COG4804	nuclease activity
EC80_RS01055	COG0551	DNA topoisomerase type I activity
EC80_RS01055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC80_RS01085	COG0776	regulation of translation
EC80_RS01090	COG1970	mechanosensitive ion channel activity
EC80_RS01095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EC80_RS01175	COG3344	reverse transcriptase
EC80_RS01255	COG2003	Belongs to the UPF0758 family
EC80_RS01275	COG1475	DNA binding
EC80_RS01280	COG4474	Belongs to the UPF0398 family
EC80_RS01345	COG1629	transport
EC80_RS01375	COG0823	Involved in the tonB-independent uptake of proteins
EC80_RS01375	COG4946	Tricorn protease homolog
EC80_RS01375	COG1506	peptidase
EC80_RS01380	COG0039	L-malate dehydrogenase activity
EC80_RS01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS01440	COG3118	belongs to the thioredoxin family
EC80_RS01445	COG0489	protein tyrosine kinase activity
EC80_RS01460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC80_RS01470	COG1570	exodeoxyribonuclease VII activity
EC80_RS01480	COG0482	sulfurtransferase activity
EC80_RS01505	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EC80_RS01510	COG0179	Fumarylacetoacetate (FAA) hydrolase
EC80_RS01515	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EC80_RS01525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EC80_RS01530	COG0052	Belongs to the universal ribosomal protein uS2 family
EC80_RS01535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EC80_RS01540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EC80_RS01555	COG0017	Asparaginyl-tRNA synthetase
EC80_RS01560	COG1187	pseudouridine synthase activity
EC80_RS01600	COG0110	maltose O-acetyltransferase activity
EC80_RS01605	COG3022	response to hydroperoxide
EC80_RS01610	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS01670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC80_RS01710	COG1442	glycosyl transferase family 8
EC80_RS01710	COG1216	Glycosyl transferase, family 2
EC80_RS01745	COG0438	transferase activity, transferring glycosyl groups
EC80_RS01840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EC80_RS01855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EC80_RS01870	COG0517	IMP dehydrogenase activity
EC80_RS01870	COG0516	GMP reductase activity
EC80_RS01875	COG0514	ATP-dependent DNA helicase (RecQ)
EC80_RS01880	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EC80_RS01890	COG0544	peptidyl-prolyl cis-trans isomerase activity
EC80_RS01895	COG0724	RNA recognition motif
EC80_RS01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EC80_RS01910	COG1127	ABC transporter
EC80_RS01915	COG0745	RESPONSE REGULATOR receiver
EC80_RS01920	COG1160	GTP binding
EC80_RS01925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EC80_RS01930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC80_RS02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC80_RS02025	COG1120	ATPase activity
EC80_RS02055	COG1192	Involved in chromosome partitioning
EC80_RS02060	COG1629	transport
EC80_RS02135	COG4974	Belongs to the 'phage' integrase family
EC80_RS02140	COG4974	Belongs to the 'phage' integrase family
EC80_RS02165	COG1696	Membrane protein involved in D-alanine export
EC80_RS02200	COG1309	transcriptional regulator
EC80_RS02205	COG2986	histidine ammonia-lyase
EC80_RS02215	COG1228	amidohydrolase
EC80_RS02225	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EC80_RS02235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC80_RS02250	COG0203	ribosomal protein L17
EC80_RS02255	COG0202	RNA polymerase activity
EC80_RS02260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EC80_RS02265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EC80_RS02270	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EC80_RS02275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EC80_RS02280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EC80_RS02295	COG0200	Binds to the 23S rRNA
EC80_RS02300	COG1841	ribosomal large subunit assembly
EC80_RS02305	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EC80_RS02310	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EC80_RS02315	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EC80_RS02320	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EC80_RS02325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EC80_RS02330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EC80_RS02335	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EC80_RS02340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EC80_RS02345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EC80_RS02350	COG0255	Belongs to the universal ribosomal protein uL29 family
EC80_RS02355	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EC80_RS02360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EC80_RS02365	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EC80_RS02370	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EC80_RS02375	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EC80_RS02380	COG0089	rRNA binding
EC80_RS02385	COG0088	Forms part of the polypeptide exit tunnel
EC80_RS02390	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EC80_RS02395	COG0051	transcription antitermination factor activity, RNA binding
EC80_RS02400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EC80_RS02405	COG0049	tRNA binding
EC80_RS02410	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EC80_RS02445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EC80_RS02450	COG0085	RNA polymerase activity
EC80_RS02455	COG0222	ribosome binding
EC80_RS02460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EC80_RS02465	COG0081	regulation of translation
EC80_RS02470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EC80_RS02515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EC80_RS02520	COG4974	Belongs to the 'phage' integrase family
EC80_RS02525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EC80_RS02530	COG0006	proline dipeptidase activity
EC80_RS02535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EC80_RS02545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC80_RS02550	COG1480	7TM receptor with intracellular HD hydrolase
EC80_RS02555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EC80_RS02565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EC80_RS02580	COG1027	Aspartate ammonia-lyase
EC80_RS02585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EC80_RS02590	COG0252	asparaginase activity
EC80_RS02605	COG2096	Adenosyltransferase
EC80_RS02640	COG0657	acetylesterase activity
EC80_RS02640	COG2755	lipolytic protein G-D-S-L family
EC80_RS02655	COG3279	Response regulator of the LytR AlgR family
EC80_RS02670	COG4771	TonB-dependent receptor
EC80_RS02690	COG2197	response regulator
EC80_RS02695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC80_RS02700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EC80_RS02735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EC80_RS02745	COG1185	polyribonucleotide nucleotidyltransferase activity
EC80_RS02760	COG4771	TonB-dependent receptor
EC80_RS02805	COG3426	butyrate kinase activity
EC80_RS02810	COG0280	phosphate acetyltransferase
EC80_RS02820	COG1619	proteins homologs of microcin C7 resistance protein MccF
EC80_RS02825	COG2234	aminopeptidase activity
EC80_RS02830	COG2166	iron-sulfur cluster assembly
EC80_RS02835	COG3655	Transcriptional regulator
EC80_RS02845	COG1266	CAAX protease self-immunity
EC80_RS02850	COG0196	riboflavin kinase activity
EC80_RS02855	COG1011	Hydrolase
EC80_RS02860	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EC80_RS02865	COG5002	protein histidine kinase activity
EC80_RS02865	COG0784	Response regulator, receiver
EC80_RS02870	COG1773	rubredoxin
EC80_RS02875	COG1283	sodium-dependent phosphate transmembrane transporter activity
EC80_RS02885	COG2205	protein histidine kinase activity
EC80_RS02910	COG0006	proline dipeptidase activity
EC80_RS02925	COG0509	glycine decarboxylation via glycine cleavage system
EC80_RS02930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EC80_RS02950	COG0793	Belongs to the peptidase S41A family
EC80_RS02955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC80_RS02995	COG4771	TonB-dependent receptor
EC80_RS03000	COG0745	RESPONSE REGULATOR receiver
EC80_RS03000	COG2205	protein histidine kinase activity
EC80_RS03000	COG3292	Two component regulator propeller
EC80_RS03005	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC80_RS03015	COG2814	Major facilitator Superfamily
EC80_RS03015	COG0477	Major facilitator Superfamily
EC80_RS03040	COG0483	inositol monophosphate 1-phosphatase activity
EC80_RS03050	COG3345	alpha-galactosidase
EC80_RS03075	COG3475	LICD family
EC80_RS03080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EC80_RS03110	COG1442	glycosyl transferase family 8
EC80_RS03150	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EC80_RS03175	COG0438	transferase activity, transferring glycosyl groups
EC80_RS03195	COG2816	NAD+ diphosphatase activity
EC80_RS03250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EC80_RS03260	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC80_RS03260	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC80_RS03265	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC80_RS03270	COG0584	glycerophosphoryl diester phosphodiesterase
EC80_RS03275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EC80_RS03280	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EC80_RS03290	COG4206	TonB-dependent receptor
EC80_RS03290	COG1629	transport
EC80_RS03305	COG1629	transport
EC80_RS03340	COG1629	transport
EC80_RS03355	COG1217	gtp-binding protein TYPA
EC80_RS03360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EC80_RS03370	COG0318	PFAM AMP-dependent synthetase and ligase
EC80_RS03380	COG4974	Belongs to the 'phage' integrase family
EC80_RS03415	COG0551	DNA topoisomerase type I activity
EC80_RS03415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC80_RS03460	COG2205	protein histidine kinase activity
EC80_RS03460	COG0784	Response regulator, receiver
EC80_RS03460	COG2198	Histidine kinase
EC80_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS03595	COG0358	DNA primase activity
EC80_RS03695	COG3119	arylsulfatase activity
EC80_RS03705	COG1629	transport
EC80_RS03705	COG4206	TonB-dependent receptor
EC80_RS03725	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC80_RS03730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EC80_RS03745	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EC80_RS03750	COG4974	Belongs to the 'phage' integrase family
EC80_RS03765	COG0606	chelatase, subunit chli
EC80_RS03870	COG0438	transferase activity, transferring glycosyl groups
EC80_RS03895	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC80_RS03900	COG0438	transferase activity, transferring glycosyl groups
EC80_RS03910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EC80_RS03915	COG0545	Peptidyl-prolyl cis-trans isomerase
EC80_RS03920	COG0545	Peptidyl-prolyl cis-trans isomerase
EC80_RS03930	COG1522	sequence-specific DNA binding
EC80_RS03950	COG3275	phosphorelay sensor kinase activity
EC80_RS03965	COG1566	PFAM secretion protein HlyD family protein
EC80_RS04035	COG1629	transport
EC80_RS04035	COG4206	TonB-dependent receptor
EC80_RS04045	COG2814	Major facilitator Superfamily
EC80_RS04065	COG3292	Two component regulator propeller
EC80_RS04065	COG2205	protein histidine kinase activity
EC80_RS04065	COG0745	RESPONSE REGULATOR receiver
EC80_RS04070	COG1621	beta-fructofuranosidase activity
EC80_RS04115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EC80_RS04120	COG3409	Peptidoglycan-binding domain 1 protein
EC80_RS04120	COG0793	Belongs to the peptidase S41A family
EC80_RS04155	COG1053	succinate dehydrogenase
EC80_RS04160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EC80_RS04185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC80_RS04185	COG0758	DNA mediated transformation
EC80_RS04195	COG0826	peptidase U32
EC80_RS04205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EC80_RS04220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EC80_RS04225	COG0557	exoribonuclease II activity
EC80_RS04250	COG1595	DNA-templated transcription, initiation
EC80_RS04275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC80_RS04290	COG0012	GTP binding
EC80_RS04295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EC80_RS04300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EC80_RS04310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC80_RS04320	COG0495	leucyl-tRNA aminoacylation
EC80_RS04325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EC80_RS04345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EC80_RS04365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EC80_RS04365	COG0731	radical SAM domain protein
EC80_RS04390	COG0659	secondary active sulfate transmembrane transporter activity
EC80_RS04395	COG1592	Rubrerythrin
EC80_RS04400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EC80_RS04420	COG0427	acetyl-CoA hydrolase
EC80_RS04430	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC80_RS04440	COG3250	beta-galactosidase activity
EC80_RS04535	COG2177	Part of the ABC transporter FtsEX involved in
EC80_RS04545	COG1968	undecaprenyl-diphosphatase activity
EC80_RS04550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EC80_RS04555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EC80_RS04560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EC80_RS04570	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EC80_RS04575	COG1611	Belongs to the LOG family
EC80_RS04590	COG0594	ribonuclease P activity
EC80_RS04595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EC80_RS04610	COG1506	peptidase
EC80_RS04610	COG0823	Involved in the tonB-independent uptake of proteins
EC80_RS04610	COG4946	Tricorn protease homolog
EC80_RS04620	COG3119	arylsulfatase activity
EC80_RS04625	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EC80_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
EC80_RS04635	COG4677	pectinesterase activity
EC80_RS04640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC80_RS04680	COG1121	(ABC) transporter
EC80_RS04690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC80_RS04690	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EC80_RS04710	COG0823	Involved in the tonB-independent uptake of proteins
EC80_RS04710	COG1506	peptidase
EC80_RS04715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EC80_RS04715	COG0116	Belongs to the methyltransferase superfamily
EC80_RS04720	COG1045	serine acetyltransferase
EC80_RS04725	COG3275	phosphorelay sensor kinase activity
EC80_RS04730	COG3279	Response regulator of the LytR AlgR family
EC80_RS04740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC80_RS04740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EC80_RS04760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EC80_RS04765	COG1694	Mazg nucleotide pyrophosphohydrolase
EC80_RS04775	COG0322	excinuclease ABC activity
EC80_RS04780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EC80_RS04810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EC80_RS04815	COG2715	membrane protein required for spore maturation
EC80_RS04825	COG2255	four-way junction helicase activity
EC80_RS04840	COG3591	Belongs to the peptidase S1B family
EC80_RS04850	COG0513	Belongs to the DEAD box helicase family
EC80_RS04860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EC80_RS04875	COG0612	Peptidase, M16
EC80_RS04895	COG1312	Catalyzes the dehydration of D-mannonate
EC80_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
EC80_RS04910	COG0681	Belongs to the peptidase S26 family
EC80_RS04920	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EC80_RS04950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC80_RS04965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS04970	COG3250	beta-galactosidase activity
EC80_RS04990	COG0215	cysteine-tRNA ligase activity
EC80_RS05000	COG0561	phosphatase activity
EC80_RS05005	COG0745	RESPONSE REGULATOR receiver
EC80_RS05065	COG0205	6-phosphofructokinase activity
EC80_RS05075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EC80_RS05080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EC80_RS05085	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EC80_RS05090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC80_RS05100	COG1216	Glycosyl transferase, family 2
EC80_RS05120	COG1442	glycosyl transferase family 8
EC80_RS05125	COG1216	Glycosyl transferase, family 2
EC80_RS05125	COG1442	glycosyl transferase family 8
EC80_RS05135	COG1216	Glycosyl transferase, family 2
EC80_RS05135	COG1442	glycosyl transferase family 8
EC80_RS05140	COG1132	(ABC) transporter
EC80_RS05145	COG0328	RNA-DNA hybrid ribonuclease activity
EC80_RS05145	COG3341	Caulimovirus viroplasmin
EC80_RS05155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EC80_RS05165	COG0326	Molecular chaperone. Has ATPase activity
EC80_RS05175	COG1166	arginine decarboxylase activity
EC80_RS05180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EC80_RS05185	COG1595	DNA-templated transcription, initiation
EC80_RS05230	COG1454	alcohol dehydrogenase
EC80_RS05235	COG0235	Class ii aldolase
EC80_RS05240	COG1070	Carbohydrate kinase
EC80_RS05245	COG0738	Major facilitator superfamily
EC80_RS05265	COG0779	Required for maturation of 30S ribosomal subunits
EC80_RS05270	COG0195	Participates in both transcription termination and antitermination
EC80_RS05275	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EC80_RS05285	COG0719	Fe-S assembly protein
EC80_RS05295	COG0396	ATPase activity
EC80_RS05300	COG0719	Fe-S assembly protein
EC80_RS05305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EC80_RS05310	COG0393	Putative heavy-metal-binding
EC80_RS05315	COG3345	alpha-galactosidase
EC80_RS05325	COG4771	TonB-dependent receptor
EC80_RS05350	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EC80_RS05355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EC80_RS05380	COG0187	DNA topoisomerase II activity
EC80_RS05385	COG0268	Binds directly to 16S ribosomal RNA
EC80_RS05395	COG1381	Involved in DNA repair and RecF pathway recombination
EC80_RS05400	COG1610	YqeY-like protein
EC80_RS05405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EC80_RS05420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EC80_RS05425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EC80_RS05430	COG0772	Belongs to the SEDS family
EC80_RS05435	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EC80_RS05440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS05445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EC80_RS05460	COG0275	rRNA processing
EC80_RS05465	COG2001	Belongs to the MraZ family
EC80_RS05500	COG4771	TonB-dependent receptor
EC80_RS05530	COG0756	dUTP diphosphatase activity
EC80_RS05545	COG4942	peptidase
EC80_RS05550	COG0745	RESPONSE REGULATOR receiver
EC80_RS05550	COG3292	Two component regulator propeller
EC80_RS05550	COG2205	protein histidine kinase activity
EC80_RS05555	COG3940	Belongs to the glycosyl hydrolase 43 family
EC80_RS05565	COG3250	beta-galactosidase activity
EC80_RS05595	COG0383	alpha-mannosidase activity
EC80_RS05595	COG0383	alpha-mannosidase activity
EC80_RS05600	COG4206	TonB-dependent receptor
EC80_RS05600	COG1629	transport
EC80_RS05620	COG3507	Belongs to the glycosyl hydrolase 43 family
EC80_RS05640	COG3537	Alpha-1,2-mannosidase
EC80_RS05650	COG2017	converts alpha-aldose to the beta-anomer
EC80_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EC80_RS05705	COG1022	Amp-dependent synthetase and ligase
EC80_RS05720	COG2954	triphosphatase activity
EC80_RS05740	COG3250	beta-galactosidase activity
EC80_RS05745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS05750	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EC80_RS05755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EC80_RS05775	COG4206	TonB-dependent receptor
EC80_RS05775	COG1629	transport
EC80_RS05780	COG3292	Two component regulator propeller
EC80_RS05780	COG0745	RESPONSE REGULATOR receiver
EC80_RS05780	COG2205	protein histidine kinase activity
EC80_RS05785	COG3292	Two component regulator propeller
EC80_RS05785	COG2205	protein histidine kinase activity
EC80_RS05785	COG0745	RESPONSE REGULATOR receiver
EC80_RS05810	COG4771	TonB-dependent receptor
EC80_RS05850	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
EC80_RS05895	COG4771	TonB-dependent receptor
EC80_RS05920	COG0423	glycine-tRNA ligase activity
EC80_RS05955	COG3005	denitrification pathway
EC80_RS05960	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EC80_RS05970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC80_RS05990	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EC80_RS06010	COG3876	Protein conserved in bacteria
EC80_RS06030	COG0463	Glycosyl transferase, family 2
EC80_RS06030	COG1216	Glycosyl transferase, family 2
EC80_RS06045	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC80_RS06050	COG3876	Protein conserved in bacteria
EC80_RS06060	COG1629	transport
EC80_RS06060	COG4206	TonB-dependent receptor
EC80_RS06070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EC80_RS06075	COG0475	glutathione-regulated potassium exporter activity
EC80_RS06075	COG0589	response to stress
EC80_RS06080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EC80_RS06095	COG0733	neurotransmitter:sodium symporter activity
EC80_RS06105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EC80_RS06115	COG0076	glutamate decarboxylase activity
EC80_RS06120	COG2066	Belongs to the glutaminase family
EC80_RS06125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS06125	COG2205	protein histidine kinase activity
EC80_RS06130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EC80_RS06135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EC80_RS06275	COG1346	cytolysis
EC80_RS06300	COG0280	phosphate acetyltransferase
EC80_RS06305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EC80_RS06310	COG1785	Belongs to the alkaline phosphatase family
EC80_RS06320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC80_RS06325	COG2003	Belongs to the UPF0758 family
EC80_RS06330	COG0463	Glycosyl transferase, family 2
EC80_RS06330	COG1216	Glycosyl transferase, family 2
EC80_RS06335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EC80_RS06340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EC80_RS06345	COG0515	serine threonine protein kinase
EC80_RS06345	COG2815	serine threonine protein kinase
EC80_RS06350	COG0564	pseudouridine synthase activity
EC80_RS06395	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
EC80_RS06420	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EC80_RS06425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EC80_RS06435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EC80_RS06455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EC80_RS06465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC80_RS06465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EC80_RS06540	COG0358	DNA primase activity
EC80_RS06685	COG0784	Response regulator, receiver
EC80_RS06685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS06685	COG2198	Histidine kinase
EC80_RS06685	COG2205	protein histidine kinase activity
EC80_RS06705	COG0551	DNA topoisomerase type I activity
EC80_RS06705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC80_RS06745	COG4974	Belongs to the 'phage' integrase family
EC80_RS06755	COG2890	protein-(glutamine-N5) methyltransferase activity
EC80_RS06760	COG2137	regulation of response to DNA damage stimulus
EC80_RS06765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EC80_RS06790	COG1929	Belongs to the glycerate kinase type-1 family
EC80_RS06800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EC80_RS06805	COG1396	sequence-specific DNA binding
EC80_RS06805	COG1917	Cupin 2, conserved barrel domain protein
EC80_RS06810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EC80_RS06815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EC80_RS06820	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EC80_RS06825	COG0137	argininosuccinate synthase activity
EC80_RS06850	COG0531	amino acid
EC80_RS06860	COG0039	L-malate dehydrogenase activity
EC80_RS06865	COG2996	Protein conserved in bacteria
EC80_RS06895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC80_RS06900	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EC80_RS06925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS06930	COG0577	efflux transmembrane transporter activity
EC80_RS06930	COG1136	(ABC) transporter
EC80_RS06935	COG0577	efflux transmembrane transporter activity
EC80_RS06935	COG1136	(ABC) transporter
EC80_RS06940	COG1136	(ABC) transporter
EC80_RS06945	COG1940	carbohydrate kinase activity
EC80_RS06950	COG0335	large ribosomal subunit rRNA binding
EC80_RS06955	COG0737	Belongs to the 5'-nucleotidase family
EC80_RS06960	COG0737	Belongs to the 5'-nucleotidase family
EC80_RS06965	COG1472	Belongs to the glycosyl hydrolase 3 family
EC80_RS06970	COG1472	Belongs to the glycosyl hydrolase 3 family
EC80_RS06975	COG1629	transport
EC80_RS06975	COG4206	TonB-dependent receptor
EC80_RS06985	COG3119	arylsulfatase activity
EC80_RS07010	COG0446	pyridine nucleotide-disulphide oxidoreductase
EC80_RS07035	COG2204	response regulator
EC80_RS07045	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EC80_RS07065	COG2205	protein histidine kinase activity
EC80_RS07070	COG5002	protein histidine kinase activity
EC80_RS07085	COG4771	TonB-dependent receptor
EC80_RS07125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EC80_RS07125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EC80_RS07130	COG0436	Aminotransferase
EC80_RS07145	COG0826	peptidase U32
EC80_RS07155	COG4771	TonB-dependent receptor
EC80_RS07165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EC80_RS07175	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EC80_RS07185	COG0489	protein tyrosine kinase activity
EC80_RS07185	COG3206	protein involved in exopolysaccharide biosynthesis
EC80_RS07195	COG0460	homoserine dehydrogenase
EC80_RS07195	COG0527	aspartate kinase activity
EC80_RS07200	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
EC80_RS07255	COG4771	TonB-dependent receptor
EC80_RS07260	COG0702	epimerase
EC80_RS07270	COG3250	beta-galactosidase activity
EC80_RS07280	COG3250	beta-galactosidase activity
EC80_RS07285	COG3507	Belongs to the glycosyl hydrolase 43 family
EC80_RS07300	COG4771	TonB-dependent receptor
EC80_RS07335	COG0628	permease
EC80_RS07340	COG1435	thymidine kinase activity
EC80_RS07350	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC80_RS07365	COG2095	MarC family integral membrane protein
EC80_RS07375	COG1629	transport
EC80_RS07385	COG4206	TonB-dependent receptor
EC80_RS07385	COG1629	transport
EC80_RS07390	COG4974	Belongs to the 'phage' integrase family
EC80_RS07400	COG4771	TonB-dependent receptor
EC80_RS07405	COG0702	epimerase
EC80_RS07410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EC80_RS07430	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EC80_RS07430	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EC80_RS07445	COG0531	amino acid
EC80_RS07455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC80_RS07460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS07465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS07505	COG1162	GTPase activity
EC80_RS07510	COG0233	cytoplasmic translational termination
EC80_RS07530	COG0443	Heat shock 70 kDa protein
EC80_RS07540	COG0528	UMP kinase activity
EC80_RS07545	COG0534	Mate efflux family protein
EC80_RS07570	COG0792	nuclease activity
EC80_RS07590	COG1183	phosphatidylcholine synthase activity
EC80_RS07595	COG0688	phosphatidylethanolamine metabolic process
EC80_RS07605	COG3118	belongs to the thioredoxin family
EC80_RS07640	COG0714	Associated with various cellular activities
EC80_RS07655	COG0802	atpase or kinase
EC80_RS07660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EC80_RS07670	COG2234	aminopeptidase activity
EC80_RS07690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EC80_RS07750	COG4974	Belongs to the 'phage' integrase family
EC80_RS07755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EC80_RS07770	COG1629	transport
EC80_RS07790	COG3250	beta-galactosidase activity
EC80_RS07795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EC80_RS07805	COG0784	Response regulator, receiver
EC80_RS07805	COG2205	protein histidine kinase activity
EC80_RS07820	COG1566	PFAM secretion protein HlyD family protein
EC80_RS07840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EC80_RS07855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC80_RS07860	COG0742	ribosomal rna small subunit methyltransferase
EC80_RS07885	COG4771	TonB-dependent receptor
EC80_RS07895	COG3537	Alpha-1,2-mannosidase
EC80_RS07910	COG3537	Alpha-1,2-mannosidase
EC80_RS07915	COG2814	Major facilitator Superfamily
EC80_RS07930	COG0739	heme binding
EC80_RS07940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC80_RS07945	COG3942	CHAP domain
EC80_RS07945	COG1388	LysM domain
EC80_RS07955	COG1475	DNA binding
EC80_RS07960	COG1192	Involved in chromosome partitioning
EC80_RS07970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EC80_RS07975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC80_RS07990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EC80_RS07995	COG0799	negative regulation of ribosome biogenesis
EC80_RS08010	COG2239	Acts as a magnesium transporter
EC80_RS08015	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EC80_RS08025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC80_RS08085	COG0668	transmembrane transport
EC80_RS08090	COG2207	Transcriptional regulator
EC80_RS08090	COG0662	Cupin 2, conserved barrel domain protein
EC80_RS08155	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
EC80_RS08155	COG0028	Belongs to the TPP enzyme family
EC80_RS08160	COG1454	alcohol dehydrogenase
EC80_RS08165	COG3475	LICD family
EC80_RS08170	COG1442	glycosyl transferase family 8
EC80_RS08170	COG1216	Glycosyl transferase, family 2
EC80_RS08215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS08220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS08245	COG0667	Aldo Keto reductase
EC80_RS08250	COG1472	Belongs to the glycosyl hydrolase 3 family
EC80_RS08255	COG4771	TonB-dependent receptor
EC80_RS08260	COG0702	epimerase
EC80_RS08300	COG5012	cobalamin binding
EC80_RS08310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EC80_RS08315	COG4124	Belongs to the glycosyl hydrolase 26 family
EC80_RS08320	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EC80_RS08325	COG2211	Major facilitator Superfamily
EC80_RS08330	COG2942	2-epimerase
EC80_RS08345	COG0251	oxidation-reduction process
EC80_RS08365	COG1404	Belongs to the peptidase S8 family
EC80_RS08365	COG4412	M6 family metalloprotease domain protein
EC80_RS08375	COG2205	protein histidine kinase activity
EC80_RS08375	COG0784	Response regulator, receiver
EC80_RS08375	COG5002	protein histidine kinase activity
EC80_RS08385	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC80_RS08390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EC80_RS08395	COG0713	ATP synthesis coupled electron transport
EC80_RS08400	COG0839	Belongs to the complex I subunit 6 family
EC80_RS08410	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EC80_RS08415	COG0649	NAD binding
EC80_RS08415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC80_RS08420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC80_RS08425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EC80_RS08435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC80_RS08440	COG0569	domain protein
EC80_RS08445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EC80_RS08450	COG1073	alpha beta
EC80_RS08465	COG0546	phosphoglycolate phosphatase activity
EC80_RS08470	COG3119	arylsulfatase activity
EC80_RS08485	COG3119	arylsulfatase activity
EC80_RS08495	COG4771	TonB-dependent receptor
EC80_RS08500	COG0745	RESPONSE REGULATOR receiver
EC80_RS08500	COG3292	Two component regulator propeller
EC80_RS08500	COG2205	protein histidine kinase activity
EC80_RS08505	COG2271	Major facilitator Superfamily
EC80_RS08525	COG0805	protein transport
EC80_RS08530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EC80_RS08535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EC80_RS08555	COG4585	Histidine kinase
EC80_RS08570	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EC80_RS08580	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC80_RS08585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EC80_RS08585	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EC80_RS08590	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EC80_RS08595	COG1078	dGTPase activity
EC80_RS08600	COG0284	orotidine-5'-phosphate decarboxylase activity
EC80_RS08605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EC80_RS08610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EC80_RS08620	COG1704	LemA family
EC80_RS08635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EC80_RS08640	COG2226	methyltransferase
EC80_RS08645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EC80_RS08650	COG1702	phosphate starvation-inducible protein PhoH
EC80_RS08660	COG2268	Band 7 protein
EC80_RS08670	COG5434	Belongs to the glycosyl hydrolase 28 family
EC80_RS08680	COG0101	tRNA pseudouridine synthase activity
EC80_RS08700	COG3250	beta-galactosidase activity
EC80_RS08705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EC80_RS08730	COG0457	Tetratricopeptide repeat
EC80_RS08735	COG2814	Major facilitator Superfamily
EC80_RS08760	COG0702	epimerase
EC80_RS08765	COG4206	TonB-dependent receptor
EC80_RS08765	COG1629	transport
EC80_RS08780	COG1629	transport
EC80_RS08780	COG4206	TonB-dependent receptor
EC80_RS08790	COG4771	TonB-dependent receptor
EC80_RS08800	COG1629	transport
EC80_RS08800	COG4206	TonB-dependent receptor
EC80_RS08810	COG0673	inositol 2-dehydrogenase activity
EC80_RS08855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EC80_RS08860	COG0793	Belongs to the peptidase S41A family
EC80_RS08865	COG2131	deaminase
EC80_RS08875	COG0339	signal peptide processing
EC80_RS08885	COG1970	mechanosensitive ion channel activity
EC80_RS08890	COG0519	Catalyzes the synthesis of GMP from XMP
EC80_RS08890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EC80_RS08900	COG4206	TonB-dependent receptor
EC80_RS08900	COG1629	transport
EC80_RS08910	COG4771	TonB-dependent receptor
EC80_RS08915	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EC80_RS08925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EC80_RS08935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EC80_RS08960	COG1242	4 iron, 4 sulfur cluster binding
EC80_RS08970	COG0363	glucosamine-6-phosphate deaminase activity
EC80_RS08980	COG0009	L-threonylcarbamoyladenylate synthase
EC80_RS08990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC80_RS08995	COG0561	phosphatase activity
EC80_RS09000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC80_RS09005	COG0626	cystathionine gamma-synthase activity
EC80_RS09060	COG0297	glycogen (starch) synthase activity
EC80_RS09065	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EC80_RS09070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EC80_RS09075	COG0543	2 iron, 2 sulfur cluster binding
EC80_RS09085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EC80_RS09095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EC80_RS09100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EC80_RS09115	COG0546	phosphoglycolate phosphatase activity
EC80_RS09120	COG0791	NLP P60 protein
EC80_RS09125	COG1131	(ABC) transporter
EC80_RS09135	COG0612	Peptidase, M16
EC80_RS09140	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EC80_RS09145	COG1597	lipid kinase activity
EC80_RS09160	COG1136	(ABC) transporter
EC80_RS09180	COG2211	Major facilitator Superfamily
EC80_RS09190	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EC80_RS09205	COG1674	ftsk spoiiie
EC80_RS09215	COG0492	ferredoxin-NADP+ reductase activity
EC80_RS09220	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS09260	COG1595	DNA-templated transcription, initiation
EC80_RS09275	COG3956	TIGRFAM MazG family protein
EC80_RS09285	COG0525	valine-tRNA ligase activity
EC80_RS09310	COG4771	TonB-dependent receptor
EC80_RS09325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EC80_RS09345	COG4771	TonB-dependent receptor
EC80_RS09350	COG0702	epimerase
EC80_RS09355	COG3119	arylsulfatase activity
EC80_RS09360	COG3119	arylsulfatase activity
EC80_RS09375	COG0653	protein targeting
EC80_RS09380	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EC80_RS09390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EC80_RS09410	COG1253	flavin adenine dinucleotide binding
EC80_RS09420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EC80_RS09430	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EC80_RS09470	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EC80_RS09505	COG2030	dehydratase
EC80_RS09520	COG0110	maltose O-acetyltransferase activity
EC80_RS09535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC80_RS09555	COG1215	transferase activity, transferring glycosyl groups
EC80_RS09565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS09580	COG4771	TonB-dependent receptor
EC80_RS09590	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EC80_RS09595	COG0563	adenylate kinase activity
EC80_RS09600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EC80_RS09605	COG1496	oxidoreductase activity
EC80_RS09625	COG2706	6-phosphogluconolactonase activity
EC80_RS09645	COG2207	Transcriptional regulator
EC80_RS09665	COG1288	antiporter activity
EC80_RS09700	COG0454	-acetyltransferase
EC80_RS09705	COG0564	pseudouridine synthase activity
EC80_RS09720	COG1501	Belongs to the glycosyl hydrolase 31 family
EC80_RS09750	COG3011	Protein conserved in bacteria
EC80_RS09765	COG0148	phosphopyruvate hydratase activity
EC80_RS09775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EC80_RS09780	COG1082	Xylose isomerase domain protein TIM barrel
EC80_RS09805	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EC80_RS09810	COG0193	aminoacyl-tRNA hydrolase activity
EC80_RS09815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EC80_RS09825	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EC80_RS09830	COG1862	Preprotein translocase
EC80_RS09840	COG0237	dephospho-CoA kinase activity
EC80_RS09855	COG0542	response to heat
EC80_RS09865	COG0583	DNA-binding transcription factor activity
EC80_RS09870	COG2855	membrane
EC80_RS09885	COG1595	DNA-templated transcription, initiation
EC80_RS09900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EC80_RS09920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EC80_RS09940	COG0443	Heat shock 70 kDa protein
EC80_RS10010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EC80_RS10030	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EC80_RS10035	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EC80_RS10040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EC80_RS10060	COG1501	Belongs to the glycosyl hydrolase 31 family
EC80_RS10080	COG1629	transport
EC80_RS10080	COG4206	TonB-dependent receptor
EC80_RS10090	COG1408	metallophosphoesterase
EC80_RS10100	COG3634	alkyl hydroperoxide reductase activity
EC80_RS10135	COG1760	l-serine dehydratase
EC80_RS10140	COG0598	Magnesium transport protein CorA
EC80_RS10145	COG1193	negative regulation of DNA recombination
EC80_RS10255	COG2205	protein histidine kinase activity
EC80_RS10255	COG0784	Response regulator, receiver
EC80_RS10260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EC80_RS10265	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC80_RS10270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EC80_RS10275	COG3189	MarR family transcriptional regulator
EC80_RS10280	COG2885	chlorophyll binding
EC80_RS10295	COG2217	Heavy metal translocating P-type atpase
EC80_RS10300	COG2855	membrane
EC80_RS10310	COG1629	transport
EC80_RS10310	COG4206	TonB-dependent receptor
EC80_RS10320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EC80_RS10320	COG2207	Transcriptional regulator
EC80_RS10345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC80_RS10345	COG4651	solute:proton antiporter activity
EC80_RS10350	COG1280	lysine exporter protein (LysE YggA)
EC80_RS10365	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EC80_RS10370	COG0561	phosphatase activity
EC80_RS10375	COG1169	isochorismate synthase
EC80_RS10380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EC80_RS10390	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EC80_RS10395	COG4948	Mandelate Racemase Muconate Lactonizing
EC80_RS10410	COG1082	Xylose isomerase domain protein TIM barrel
EC80_RS10425	COG4771	TonB-dependent receptor
EC80_RS10455	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EC80_RS10460	COG0783	Belongs to the Dps family
EC80_RS10485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EC80_RS10505	COG4974	Belongs to the 'phage' integrase family
EC80_RS10605	COG3344	reverse transcriptase
EC80_RS10710	COG0551	DNA topoisomerase type I activity
EC80_RS10710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC80_RS10830	COG4974	Belongs to the 'phage' integrase family
EC80_RS10835	COG1309	transcriptional regulator
EC80_RS10850	COG2755	lipolytic protein G-D-S-L family
EC80_RS10850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EC80_RS10875	COG1253	flavin adenine dinucleotide binding
EC80_RS10880	COG0501	Belongs to the peptidase M48B family
EC80_RS10910	COG2873	o-acetylhomoserine
EC80_RS10930	COG1757	Na H antiporter
EC80_RS10945	COG2814	Major facilitator Superfamily
EC80_RS10950	COG4953	penicillin-binding protein 1C
EC80_RS10955	COG2373	Large extracellular alpha-helical protein
EC80_RS10965	COG1918	ferrous iron import across plasma membrane
EC80_RS10965	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EC80_RS11025	COG2244	polysaccharide biosynthetic process
EC80_RS11035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EC80_RS11080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EC80_RS11085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC80_RS11100	COG0490	domain, Protein
EC80_RS11100	COG0471	metal ion transport
EC80_RS11115	COG0346	lactoylglutathione lyase activity
EC80_RS11130	COG0259	pyridoxamine-phosphate oxidase activity
EC80_RS11135	COG1741	Belongs to the pirin family
EC80_RS11150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC80_RS11180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EC80_RS11190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EC80_RS11205	COG1595	DNA-templated transcription, initiation
EC80_RS11230	COG0686	Belongs to the AlaDH PNT family
EC80_RS11250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EC80_RS11295	COG0488	(ABC) transporter
EC80_RS11300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC80_RS11305	COG3059	membrane
EC80_RS11310	COG2207	Transcriptional regulator
EC80_RS11310	COG0662	Cupin 2, conserved barrel domain protein
EC80_RS11315	COG0295	cytidine deaminase activity
EC80_RS11320	COG1705	Flagellar rod assembly protein muramidase FlgJ
EC80_RS11320	COG1388	LysM domain
EC80_RS11335	COG0577	efflux transmembrane transporter activity
EC80_RS11345	COG0577	efflux transmembrane transporter activity
EC80_RS11355	COG0577	efflux transmembrane transporter activity
EC80_RS11365	COG0577	efflux transmembrane transporter activity
EC80_RS11365	COG1136	(ABC) transporter
EC80_RS11375	COG0662	Cupin 2, conserved barrel domain protein
EC80_RS11375	COG2207	Transcriptional regulator
EC80_RS11390	COG1136	(ABC) transporter
EC80_RS11395	COG1136	(ABC) transporter
EC80_RS11415	COG2205	protein histidine kinase activity
EC80_RS11415	COG0784	Response regulator, receiver
EC80_RS11425	COG2204	response regulator
EC80_RS11430	COG4191	Histidine kinase
EC80_RS11480	COG0732	type I restriction modification DNA specificity domain
EC80_RS11490	COG4974	Belongs to the 'phage' integrase family
EC80_RS11520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC80_RS11540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS11550	COG1442	glycosyl transferase family 8
EC80_RS11570	COG0463	Glycosyl transferase, family 2
EC80_RS11595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS11600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS11610	COG1396	sequence-specific DNA binding
EC80_RS11625	COG1530	ribonuclease E activity
EC80_RS11640	COG3119	arylsulfatase activity
EC80_RS11645	COG0629	single-stranded DNA binding
EC80_RS11710	COG4206	TonB-dependent receptor
EC80_RS11735	COG0745	RESPONSE REGULATOR receiver
EC80_RS11760	COG0488	(ABC) transporter
EC80_RS11775	COG5492	domain, Protein
EC80_RS11785	COG0436	Aminotransferase
EC80_RS11790	COG4591	ABC-type transport system involved in lipoprotein release permease component
EC80_RS11795	COG1215	transferase activity, transferring glycosyl groups
EC80_RS11800	COG0628	permease
EC80_RS11820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS11830	COG0577	efflux transmembrane transporter activity
EC80_RS11830	COG1136	(ABC) transporter
EC80_RS11835	COG1136	(ABC) transporter
EC80_RS11835	COG0577	efflux transmembrane transporter activity
EC80_RS11840	COG1252	NADH dehydrogenase
EC80_RS11870	COG4771	TonB-dependent receptor
EC80_RS11880	COG1620	l-lactate permease
EC80_RS11900	COG3047	cAMP biosynthetic process
EC80_RS11900	COG2885	chlorophyll binding
EC80_RS11910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC80_RS11915	COG0439	Biotin carboxylase
EC80_RS11920	COG0511	ligase activity, forming carbon-carbon bonds
EC80_RS11930	COG2226	methyltransferase
EC80_RS11935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EC80_RS11970	COG2205	protein histidine kinase activity
EC80_RS11970	COG2198	Histidine kinase
EC80_RS11970	COG0784	Response regulator, receiver
EC80_RS11975	COG0508	dehydrogenase complex catalyzes the overall conversion of
EC80_RS11980	COG0022	dehydrogenase e1 component
EC80_RS11985	COG0716	FMN binding
EC80_RS11990	COG2264	protein methyltransferase activity
EC80_RS12005	COG0590	tRNA wobble adenosine to inosine editing
EC80_RS12030	COG0673	inositol 2-dehydrogenase activity
EC80_RS12035	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC80_RS12085	COG0698	ribose 5-phosphate isomerase
EC80_RS12090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EC80_RS12095	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EC80_RS12110	COG1482	cell wall glycoprotein biosynthetic process
EC80_RS12130	COG0513	Belongs to the DEAD box helicase family
EC80_RS12135	COG4221	oxidoreductase activity
EC80_RS12145	COG3250	beta-galactosidase activity
EC80_RS12155	COG0471	metal ion transport
EC80_RS12155	COG3273	potassium ion transport
EC80_RS12160	COG0529	Catalyzes the synthesis of activated sulfate
EC80_RS12165	COG0175	sulfate reduction
EC80_RS12185	COG2885	chlorophyll binding
EC80_RS12205	COG4974	Belongs to the 'phage' integrase family
EC80_RS12230	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EC80_RS12235	COG0242	peptide deformylase activity
EC80_RS12250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EC80_RS12255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EC80_RS12260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EC80_RS12265	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EC80_RS12275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EC80_RS12280	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EC80_RS12285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EC80_RS12285	COG1013	pyruvate-flavodoxin oxidoreductase activity
EC80_RS12285	COG0674	pyruvate-flavodoxin oxidoreductase activity
EC80_RS12285	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EC80_RS12295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EC80_RS12335	COG1940	carbohydrate kinase activity
EC80_RS12340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC80_RS12350	COG2271	Major facilitator Superfamily
EC80_RS12355	COG2731	YhcH YjgK YiaL family protein
EC80_RS12360	COG1629	transport
EC80_RS12365	COG0702	epimerase
EC80_RS12385	COG4771	TonB-dependent receptor
EC80_RS12390	COG0702	epimerase
EC80_RS12395	COG4771	TonB-dependent receptor
EC80_RS12400	COG0702	epimerase
EC80_RS12410	COG1629	transport
EC80_RS12410	COG4206	TonB-dependent receptor
EC80_RS12415	COG4206	TonB-dependent receptor
EC80_RS12415	COG1629	transport
EC80_RS12430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS12450	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS12460	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS12465	COG3537	Alpha-1,2-mannosidase
EC80_RS12470	COG3250	beta-galactosidase activity
EC80_RS12475	COG4771	TonB-dependent receptor
EC80_RS12480	COG0702	epimerase
EC80_RS12485	COG0484	heat shock protein binding
EC80_RS12490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EC80_RS12495	COG0488	(ABC) transporter
EC80_RS12500	COG1595	DNA-templated transcription, initiation
EC80_RS12600	COG4974	Belongs to the 'phage' integrase family
EC80_RS12605	COG2885	chlorophyll binding
EC80_RS12720	COG2183	response to ionizing radiation
EC80_RS12725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS12725	COG2205	protein histidine kinase activity
EC80_RS12730	COG0737	Belongs to the 5'-nucleotidase family
EC80_RS12735	COG1956	GAF domain-containing protein
EC80_RS12745	COG4771	TonB-dependent receptor
EC80_RS12770	COG0534	Mate efflux family protein
EC80_RS12785	COG4771	TonB-dependent receptor
EC80_RS12815	COG0534	Mate efflux family protein
EC80_RS12825	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EC80_RS12835	COG0318	PFAM AMP-dependent synthetase and ligase
EC80_RS12840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS12845	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EC80_RS12880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC80_RS12915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC80_RS12925	COG1028	Short-chain dehydrogenase reductase Sdr
EC80_RS12945	COG0463	Glycosyl transferase, family 2
EC80_RS12945	COG1216	Glycosyl transferase, family 2
EC80_RS12980	COG1086	Polysaccharide biosynthesis protein
EC80_RS12990	COG1091	dTDP-4-dehydrorhamnose reductase activity
EC80_RS13000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS13005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS13020	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EC80_RS13025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EC80_RS13030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EC80_RS13035	COG0363	glucosamine-6-phosphate deaminase activity
EC80_RS13095	COG3279	Response regulator of the LytR AlgR family
EC80_RS13105	COG0577	efflux transmembrane transporter activity
EC80_RS13105	COG1136	(ABC) transporter
EC80_RS13110	COG1136	(ABC) transporter
EC80_RS13115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS13150	COG4884	unkown
EC80_RS13150	COG3831	ATPase activity
EC80_RS13165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC80_RS13175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EC80_RS13180	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EC80_RS13185	COG3250	beta-galactosidase activity
EC80_RS13210	COG0501	Belongs to the peptidase M48B family
EC80_RS13215	COG1704	LemA family
EC80_RS13220	COG1595	DNA-templated transcription, initiation
EC80_RS13230	COG1629	transport
EC80_RS13230	COG4206	TonB-dependent receptor
EC80_RS13240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EC80_RS13245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC80_RS13245	COG2885	chlorophyll binding
EC80_RS13255	COG0697	spore germination
EC80_RS13290	COG0656	L-ascorbic acid biosynthetic process
EC80_RS13300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EC80_RS13305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EC80_RS13310	COG2814	Major facilitator Superfamily
EC80_RS13315	COG4771	TonB-dependent receptor
EC80_RS13320	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC80_RS13325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EC80_RS13530	COG0739	heme binding
EC80_RS13530	COG0741	lytic transglycosylase activity
EC80_RS13530	COG1196	nuclear chromosome segregation
EC80_RS13560	COG1192	Involved in chromosome partitioning
EC80_RS13570	COG3392	D12 class N6 adenine-specific DNA methyltransferase
EC80_RS13595	COG0702	epimerase
EC80_RS13600	COG4771	TonB-dependent receptor
EC80_RS13715	COG0326	Molecular chaperone. Has ATPase activity
EC80_RS13755	COG0546	phosphoglycolate phosphatase activity
EC80_RS13800	COG0488	(ABC) transporter
EC80_RS13820	COG3850	Histidine kinase
EC80_RS13820	COG4999	Histidine kinase
EC80_RS13820	COG2205	protein histidine kinase activity
EC80_RS13820	COG3437	response regulator, receiver
EC80_RS13840	COG0438	transferase activity, transferring glycosyl groups
EC80_RS13850	COG2244	polysaccharide biosynthetic process
EC80_RS13855	COG1442	glycosyl transferase family 8
EC80_RS13855	COG1216	Glycosyl transferase, family 2
EC80_RS13870	COG1215	transferase activity, transferring glycosyl groups
EC80_RS13900	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC80_RS13905	COG1805	sodium ion transport
EC80_RS13910	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EC80_RS13940	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EC80_RS13945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EC80_RS13955	COG0545	Peptidyl-prolyl cis-trans isomerase
EC80_RS13960	COG1739	Uncharacterized protein family UPF0029
EC80_RS13970	COG0778	Nitroreductase
EC80_RS13975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC80_RS13975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EC80_RS13980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EC80_RS14010	COG2217	Heavy metal translocating P-type atpase
EC80_RS14020	COG0321	lipoyl(octanoyl) transferase activity
EC80_RS14040	COG3852	Histidine kinase
EC80_RS14045	COG2204	response regulator
EC80_RS14060	COG1136	(ABC) transporter
EC80_RS14075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC80_RS14085	COG1755	Isoprenylcysteine carboxyl methyltransferase
EC80_RS14095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EC80_RS14110	COG1678	Uncharacterized ACR, COG1678
EC80_RS14155	COG4771	TonB-dependent receptor
EC80_RS14165	COG3119	arylsulfatase activity
EC80_RS14170	COG3250	beta-galactosidase activity
EC80_RS14185	COG0681	Belongs to the peptidase S26 family
EC80_RS14190	COG0697	spore germination
EC80_RS14220	COG3969	phosphoadenosine phosphosulfate
EC80_RS14225	COG1475	DNA binding
EC80_RS14280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS14285	COG0745	RESPONSE REGULATOR receiver
EC80_RS14295	COG1074	ATP-dependent DNA helicase activity
EC80_RS14300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS14310	COG4206	TonB-dependent receptor
EC80_RS14310	COG1629	transport
EC80_RS14320	COG4974	Belongs to the 'phage' integrase family
EC80_RS14410	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EC80_RS14430	COG1022	Amp-dependent synthetase and ligase
EC80_RS14435	COG3263	regulation of cellular component size
EC80_RS14445	COG1151	hydroxylamine reductase activity
EC80_RS14460	COG2204	response regulator
EC80_RS14480	COG1136	(ABC) transporter
EC80_RS14485	COG0577	efflux transmembrane transporter activity
EC80_RS14485	COG1136	(ABC) transporter
EC80_RS14495	COG1136	(ABC) transporter
EC80_RS14505	COG0534	Mate efflux family protein
EC80_RS14515	COG0167	dihydroorotate dehydrogenase activity
EC80_RS14520	COG2755	lipolytic protein G-D-S-L family
EC80_RS14520	COG0657	acetylesterase activity
EC80_RS14525	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EC80_RS14540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EC80_RS14565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EC80_RS14575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EC80_RS14585	COG0356	it plays a direct role in the translocation of protons across the membrane
EC80_RS14590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC80_RS14595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EC80_RS14600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC80_RS14605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EC80_RS14610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EC80_RS14615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EC80_RS14620	COG3118	belongs to the thioredoxin family
EC80_RS14640	COG0745	RESPONSE REGULATOR receiver
EC80_RS14645	COG5002	protein histidine kinase activity
EC80_RS14680	COG1120	ATPase activity
EC80_RS14685	COG1091	dTDP-4-dehydrorhamnose reductase activity
EC80_RS14710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EC80_RS14770	COG0551	DNA topoisomerase type I activity
EC80_RS14770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EC80_RS14825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EC80_RS14860	COG1475	DNA binding
EC80_RS14960	COG5290	Psort location Cytoplasmic, score
EC80_RS14970	COG0596	Alpha beta hydrolase
EC80_RS15015	COG4974	Belongs to the 'phage' integrase family
EC80_RS15020	COG4974	Belongs to the 'phage' integrase family
EC80_RS15060	COG4974	Belongs to the 'phage' integrase family
EC80_RS15065	COG4974	Belongs to the 'phage' integrase family
EC80_RS15070	COG4974	Belongs to the 'phage' integrase family
EC80_RS15085	COG1431	PFAM Stem cell self-renewal protein Piwi
EC80_RS15095	COG1196	nuclear chromosome segregation
EC80_RS15170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EC80_RS15175	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EC80_RS15195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EC80_RS15200	COG1064	alcohol dehydrogenase
EC80_RS15215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EC80_RS15225	COG2202	Pas domain
EC80_RS15225	COG2205	protein histidine kinase activity
EC80_RS15230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EC80_RS15240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EC80_RS15255	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EC80_RS15260	COG0540	Belongs to the ATCase OTCase family
EC80_RS15270	COG2431	L-lysine efflux transmembrane transporter activity
EC80_RS15300	COG2837	iron assimilation
EC80_RS15310	COG1629	transport
EC80_RS15310	COG4206	TonB-dependent receptor
EC80_RS15330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EC80_RS15340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EC80_RS15355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EC80_RS15360	COG2205	protein histidine kinase activity
EC80_RS15380	COG2135	peptidase activity
EC80_RS15390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC80_RS15395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EC80_RS15420	COG0673	inositol 2-dehydrogenase activity
EC80_RS15435	COG2223	nitrite transmembrane transporter activity
EC80_RS15455	COG0671	phosphoesterase, PA-phosphatase related
EC80_RS15470	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EC80_RS15475	COG0045	succinate-CoA ligase (ADP-forming) activity
EC80_RS15480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EC80_RS15485	COG0351	phosphomethylpyrimidine kinase
EC80_RS15505	COG0477	Major facilitator Superfamily
EC80_RS15505	COG2814	Major facilitator Superfamily
EC80_RS15515	COG3153	acetyltransferase
EC80_RS15515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC80_RS15520	COG0450	alkyl hydroperoxide reductase
EC80_RS15525	COG0724	RNA recognition motif
EC80_RS15530	COG1858	cytochrome C peroxidase
EC80_RS15535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EC80_RS15560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EC80_RS15570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EC80_RS15585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EC80_RS15635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC80_RS15645	COG1904	glucuronate isomerase
EC80_RS15675	COG0513	Belongs to the DEAD box helicase family
EC80_RS15680	COG0560	Phosphoserine phosphatase
EC80_RS15680	COG3830	Belongs to the UPF0237 family
EC80_RS15705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EC80_RS15710	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EC80_RS15845	COG0653	protein targeting
EC80_RS15850	COG3935	DnaD domain protein
EC80_RS16005	COG4974	Belongs to the 'phage' integrase family
EC80_RS16065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EC80_RS16070	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS16080	COG4771	TonB-dependent receptor
EC80_RS16140	COG0010	Belongs to the arginase family
EC80_RS16145	COG0058	SHG alpha-glucan phosphorylase activity
EC80_RS16150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC80_RS16150	COG4651	solute:proton antiporter activity
EC80_RS16155	COG0205	6-phosphofructokinase activity
EC80_RS16170	COG0588	phosphoglycerate mutase activity
EC80_RS16175	COG1830	Aldolase
EC80_RS16185	COG2095	MarC family integral membrane protein
EC80_RS16230	COG1477	protein flavinylation
EC80_RS16290	COG2204	response regulator
EC80_RS16340	COG0577	efflux transmembrane transporter activity
EC80_RS16340	COG1136	(ABC) transporter
EC80_RS16350	COG0156	8-amino-7-oxononanoate synthase activity
EC80_RS16355	COG1597	lipid kinase activity
EC80_RS16360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EC80_RS16385	COG0577	efflux transmembrane transporter activity
EC80_RS16385	COG1136	(ABC) transporter
EC80_RS16410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EC80_RS16440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC80_RS16460	COG0543	2 iron, 2 sulfur cluster binding
EC80_RS16465	COG0167	dihydroorotate dehydrogenase activity
EC80_RS16470	COG0336	Belongs to the RNA methyltransferase TrmD family
EC80_RS16475	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EC80_RS16480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EC80_RS16505	COG0326	Molecular chaperone. Has ATPase activity
EC80_RS16510	COG0542	response to heat
EC80_RS16555	COG2304	oxidoreductase activity
EC80_RS16570	COG0714	Associated with various cellular activities
EC80_RS16575	COG1652	LysM domain
EC80_RS16585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EC80_RS16590	COG0552	protein localization to endoplasmic reticulum
EC80_RS16600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EC80_RS16605	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EC80_RS16610	COG1058	Belongs to the CinA family
EC80_RS16610	COG1546	Belongs to the CinA family
EC80_RS16615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EC80_RS16630	COG0442	prolyl-tRNA aminoacylation
EC80_RS16645	COG4946	Tricorn protease homolog
EC80_RS16645	COG0793	Belongs to the peptidase S41A family
EC80_RS16665	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EC80_RS16680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EC80_RS16690	COG1492	cobalamin metabolic process
EC80_RS16730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS16750	COG2096	Adenosyltransferase
EC80_RS16755	COG1797	cobyrinic acid a,c-diamide synthase activity
EC80_RS16770	COG2966	Psort location CytoplasmicMembrane, score
EC80_RS16785	COG4771	TonB-dependent receptor
EC80_RS16795	COG4774	siderophore transport
EC80_RS16820	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EC80_RS16925	COG0305	Participates in initiation and elongation during chromosome replication
EC80_RS16935	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC80_RS17010	COG0352	thiamine-phosphate diphosphorylase activity
EC80_RS17015	COG2022	thiamine diphosphate biosynthetic process
EC80_RS17020	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EC80_RS17035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EC80_RS17040	COG0352	thiamine-phosphate diphosphorylase activity
EC80_RS17055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EC80_RS17055	COG0574	Belongs to the PEP-utilizing enzyme family
EC80_RS17060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EC80_RS17065	COG0564	pseudouridine synthase activity
EC80_RS17080	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EC80_RS17120	COG0024	Methionine aminopeptidase
EC80_RS17140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EC80_RS17150	COG0481	GTPase activity
EC80_RS17170	COG0708	Exodeoxyribonuclease III
EC80_RS17175	COG1914	H( )-stimulated, divalent metal cation uptake system
EC80_RS17195	COG0217	transcriptional regulatory protein
EC80_RS17200	COG0072	phenylalanine-tRNA ligase activity
EC80_RS17200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EC80_RS17205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS17220	COG1216	Glycosyl transferase, family 2
EC80_RS17230	COG1216	Glycosyl transferase, family 2
EC80_RS17235	COG1216	Glycosyl transferase, family 2
EC80_RS17260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS17270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC80_RS17280	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
EC80_RS17310	COG0305	Participates in initiation and elongation during chromosome replication
EC80_RS17315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EC80_RS17330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EC80_RS17335	COG4657	Part of a membrane complex involved in electron transport
EC80_RS17340	COG4660	Part of a membrane complex involved in electron transport
EC80_RS17345	COG4659	FMN binding
EC80_RS17350	COG4658	electron transport chain
EC80_RS17355	COG4656	Part of a membrane complex involved in electron transport
EC80_RS17380	COG0504	CTP synthase activity
EC80_RS17390	COG0534	Mate efflux family protein
EC80_RS17395	COG0823	Involved in the tonB-independent uptake of proteins
EC80_RS17395	COG1506	peptidase
EC80_RS17415	COG0110	maltose O-acetyltransferase activity
EC80_RS17425	COG1695	Transcriptional regulator
EC80_RS17440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EC80_RS17450	COG1388	LysM domain
EC80_RS17450	COG3942	CHAP domain
EC80_RS17480	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EC80_RS17485	COG0556	nucleotide-excision repair
EC80_RS17490	COG2949	membrane
EC80_RS17500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EC80_RS17520	COG0842	Transport permease protein
EC80_RS17525	COG0842	Transport permease protein
EC80_RS17530	COG1131	(ABC) transporter
EC80_RS17565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EC80_RS17570	COG0505	Belongs to the CarA family
EC80_RS17585	COG0067	glutamate synthase
EC80_RS17585	COG0069	glutamate synthase activity
EC80_RS17585	COG0070	glutamate synthase
EC80_RS17595	COG0367	asparagine synthase
EC80_RS17635	COG1979	alcohol dehydrogenase
EC80_RS17645	COG0133	tryptophan synthase activity
EC80_RS17650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EC80_RS17665	COG0134	indole-3-glycerol-phosphate synthase activity
EC80_RS17670	COG0135	phosphoribosylanthranilate isomerase activity
EC80_RS17675	COG0159	tryptophan synthase activity
EC80_RS17680	COG0252	asparaginase activity
EC80_RS17690	COG2205	protein histidine kinase activity
EC80_RS17690	COG3292	Two component regulator propeller
EC80_RS17690	COG0745	RESPONSE REGULATOR receiver
EC80_RS17695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EC80_RS17705	COG0110	maltose O-acetyltransferase activity
EC80_RS17710	COG2197	response regulator
EC80_RS17720	COG0138	bifunctional purine biosynthesis protein purh
EC80_RS17725	COG0716	FMN binding
EC80_RS17750	COG1858	cytochrome C peroxidase
EC80_RS17760	COG4771	TonB-dependent receptor
EC80_RS17775	COG1132	(ABC) transporter
EC80_RS17790	COG2814	Major facilitator Superfamily
EC80_RS17795	COG1566	PFAM secretion protein HlyD family protein
EC80_RS17845	COG4771	TonB-dependent receptor
EC80_RS17885	COG3610	response to peptide
EC80_RS17900	COG1609	Transcriptional regulator
EC80_RS17910	COG1733	regulation of RNA biosynthetic process
EC80_RS17920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS17920	COG2205	protein histidine kinase activity
EC80_RS17920	COG2198	Histidine kinase
EC80_RS17920	COG0784	Response regulator, receiver
EC80_RS17930	COG5002	protein histidine kinase activity
EC80_RS17935	COG0745	RESPONSE REGULATOR receiver
EC80_RS17955	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EC80_RS17960	COG1690	Belongs to the RtcB family
EC80_RS17980	COG0228	four-way junction DNA binding
EC80_RS17995	COG0724	RNA recognition motif
EC80_RS18005	COG1177	transmembrane transport
EC80_RS18010	COG1176	ABC-type spermidine putrescine transport system, permease component I
EC80_RS18020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC80_RS18035	COG0058	SHG alpha-glucan phosphorylase activity
EC80_RS18045	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EC80_RS18065	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EC80_RS18130	COG0745	RESPONSE REGULATOR receiver
EC80_RS18135	COG5002	protein histidine kinase activity
EC80_RS18165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EC80_RS18175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EC80_RS18185	COG4948	Mandelate Racemase Muconate Lactonizing
EC80_RS18200	COG1295	ribonuclease BN
EC80_RS18205	COG0778	Nitroreductase
EC80_RS18215	COG0704	Plays a role in the regulation of phosphate uptake
EC80_RS18220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EC80_RS18225	COG0581	inorganic phosphate transmembrane transporter activity
EC80_RS18230	COG0573	inorganic phosphate transmembrane transporter activity
EC80_RS18240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EC80_RS18250	COG0586	Pfam SNARE associated Golgi protein
EC80_RS18265	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EC80_RS18300	COG3023	N-Acetylmuramoyl-L-alanine amidase
EC80_RS18380	COG1045	serine acetyltransferase
EC80_RS18390	COG0438	transferase activity, transferring glycosyl groups
EC80_RS18425	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EC80_RS18470	COG0662	Cupin 2, conserved barrel domain protein
EC80_RS18470	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EC80_RS18475	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EC80_RS18495	COG1363	Peptidase, m42
EC80_RS18540	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EC80_RS18545	COG0167	dihydroorotate dehydrogenase activity
EC80_RS18610	COG5002	protein histidine kinase activity
EC80_RS18625	COG2172	sigma factor antagonist activity
EC80_RS18650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EC80_RS18680	COG0497	DNA recombination
EC80_RS18690	COG2176	DNA-directed DNA polymerase activity
EC80_RS18690	COG5002	protein histidine kinase activity
EC80_RS18695	COG0592	DNA-directed DNA polymerase activity
EC80_RS18710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EC80_RS18710	COG0321	lipoyl(octanoyl) transferase activity
EC80_RS18725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS18735	COG0156	8-amino-7-oxononanoate synthase activity
EC80_RS18850	COG0019	diaminopimelate decarboxylase activity
EC80_RS18855	COG0527	aspartate kinase activity
EC80_RS18860	COG2884	Cell division ATP-binding protein ftsE
EC80_RS18865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EC80_RS18865	COG0140	phosphoribosyl-ATP diphosphatase activity
EC80_RS18870	COG0107	imidazoleglycerol-phosphate synthase activity
EC80_RS18875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EC80_RS18895	COG3586	endonuclease activity
EC80_RS18935	COG4977	sequence-specific DNA binding
EC80_RS18935	COG1917	Cupin 2, conserved barrel domain protein
EC80_RS18945	COG0693	protein deglycase activity
EC80_RS18960	COG0494	nUDIX hydrolase
EC80_RS18975	COG3326	Membrane
EC80_RS19075	COG0561	phosphatase activity
EC80_RS19080	COG1629	transport
EC80_RS19080	COG4206	TonB-dependent receptor
EC80_RS19130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC80_RS19140	COG0363	glucosamine-6-phosphate deaminase activity
EC80_RS19180	COG1032	radical SAM domain protein
EC80_RS19185	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EC80_RS19190	COG0463	Glycosyl transferase, family 2
EC80_RS19195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EC80_RS19200	COG0646	methionine synthase
EC80_RS19200	COG1410	methionine synthase
EC80_RS19240	COG1408	metallophosphoesterase
EC80_RS19245	COG1132	(ABC) transporter
EC80_RS19250	COG1132	(ABC) transporter
EC80_RS19260	COG0420	3'-5' exonuclease activity
EC80_RS19295	COG0681	Belongs to the peptidase S26 family
EC80_RS19395	COG0641	radical SAM
EC80_RS19400	COG3591	Belongs to the peptidase S1B family
EC80_RS19405	COG3591	Belongs to the peptidase S1B family
EC80_RS19440	COG1592	Rubrerythrin
EC80_RS19440	COG1773	rubredoxin
EC80_RS19450	COG3152	Membrane
EC80_RS19455	COG0339	signal peptide processing
EC80_RS19460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EC80_RS19460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EC80_RS19470	COG4206	TonB-dependent receptor
EC80_RS19470	COG1629	transport
EC80_RS19485	COG0131	Imidazoleglycerol-phosphate dehydratase
EC80_RS19485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EC80_RS19495	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EC80_RS19500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EC80_RS19510	COG1741	Belongs to the pirin family
EC80_RS19515	COG4232	protein-disulfide reductase activity
EC80_RS19525	COG0572	uridine kinase
EC80_RS19530	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EC80_RS19535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EC80_RS19545	COG1410	methionine synthase
EC80_RS19545	COG0646	methionine synthase
EC80_RS19550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EC80_RS19585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EC80_RS19595	COG1295	ribonuclease BN
EC80_RS19605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS19610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS19615	COG1216	Glycosyl transferase, family 2
EC80_RS19660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC80_RS19670	COG1442	glycosyl transferase family 8
EC80_RS19670	COG1216	Glycosyl transferase, family 2
EC80_RS19675	COG0726	polysaccharide deacetylase
EC80_RS19730	COG2202	Pas domain
EC80_RS19730	COG2205	protein histidine kinase activity
EC80_RS19735	COG0534	Mate efflux family protein
EC80_RS19740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EC80_RS19745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC80_RS19750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EC80_RS19755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC80_RS19820	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EC80_RS19860	COG2195	Cleaves the N-terminal amino acid of tripeptides
EC80_RS19870	COG0668	transmembrane transport
EC80_RS19875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EC80_RS19885	COG3250	beta-galactosidase activity
EC80_RS19890	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS19895	COG3119	arylsulfatase activity
EC80_RS19900	COG3119	arylsulfatase activity
EC80_RS19905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS19910	COG2205	protein histidine kinase activity
EC80_RS19910	COG0745	RESPONSE REGULATOR receiver
EC80_RS19910	COG3292	Two component regulator propeller
EC80_RS19915	COG1830	Aldolase
EC80_RS19920	COG0588	phosphoglycerate mutase activity
EC80_RS19925	COG1119	ATPase activity
EC80_RS19930	COG3119	arylsulfatase activity
EC80_RS19935	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS19945	COG4206	TonB-dependent receptor
EC80_RS19945	COG1629	transport
EC80_RS19960	COG1523	belongs to the glycosyl hydrolase 13 family
EC80_RS19965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EC80_RS19985	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EC80_RS20000	COG0126	phosphoglycerate kinase activity
EC80_RS20015	COG2311	Membrane
EC80_RS20065	COG0424	maF-like protein
EC80_RS20070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EC80_RS20085	COG0778	Nitroreductase
EC80_RS20090	COG0288	reversible hydration of carbon dioxide
EC80_RS20105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC80_RS20115	COG5016	pyruvate
EC80_RS20115	COG0511	ligase activity, forming carbon-carbon bonds
EC80_RS20120	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EC80_RS20135	COG0366	Alpha amylase catalytic
EC80_RS20155	COG0191	fructose-bisphosphate aldolase activity
EC80_RS20165	COG0254	rRNA binding
EC80_RS20170	COG5002	protein histidine kinase activity
EC80_RS20190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EC80_RS20195	COG4206	TonB-dependent receptor
EC80_RS20195	COG1629	transport
EC80_RS20200	COG1609	Transcriptional regulator
EC80_RS20275	COG1554	hydrolase, family 65, central catalytic
EC80_RS20280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS20285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC80_RS20310	COG0745	RESPONSE REGULATOR receiver
EC80_RS20310	COG2205	protein histidine kinase activity
EC80_RS20310	COG3292	Two component regulator propeller
EC80_RS20325	COG1649	PFAM Uncharacterised BCR, COG1649
EC80_RS20345	COG1966	Carbon starvation protein
EC80_RS20350	COG1649	PFAM Uncharacterised BCR, COG1649
EC80_RS20355	COG2205	protein histidine kinase activity
EC80_RS20355	COG3437	response regulator, receiver
EC80_RS20355	COG3850	Histidine kinase
EC80_RS20355	COG4999	Histidine kinase
EC80_RS20405	COG2113	Glycine betaine
EC80_RS20410	COG4176	ABC-type proline glycine betaine transport system permease component
EC80_RS20425	COG0745	RESPONSE REGULATOR receiver
EC80_RS20425	COG2205	protein histidine kinase activity
EC80_RS20425	COG3292	Two component regulator propeller
EC80_RS20430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EC80_RS20430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EC80_RS20440	COG1621	beta-fructofuranosidase activity
EC80_RS20470	COG0420	3'-5' exonuclease activity
EC80_RS20520	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC80_RS20525	COG0475	glutathione-regulated potassium exporter activity
EC80_RS20550	COG3015	lipoprotein NlpE involved in copper resistance
EC80_RS20560	COG3279	Response regulator of the LytR AlgR family
EC80_RS20575	COG0702	epimerase
EC80_RS20590	COG4948	Mandelate Racemase Muconate Lactonizing
EC80_RS20595	COG1629	transport
EC80_RS20595	COG4206	TonB-dependent receptor
EC80_RS20600	COG0702	epimerase
EC80_RS20620	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EC80_RS20640	COG0484	heat shock protein binding
EC80_RS20645	COG2205	protein histidine kinase activity
EC80_RS20645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS20650	COG2194	sulfuric ester hydrolase activity
EC80_RS20700	COG0028	Belongs to the TPP enzyme family
EC80_RS20725	COG0459	protein refolding
EC80_RS20730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EC80_RS20770	COG2326	polyphosphate kinase activity
EC80_RS20820	COG3537	Alpha-1,2-mannosidase
EC80_RS20825	COG1506	peptidase
EC80_RS20825	COG0823	Involved in the tonB-independent uptake of proteins
EC80_RS20855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EC80_RS20890	COG0514	ATP-dependent DNA helicase (RecQ)
EC80_RS20905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EC80_RS20915	COG0671	phosphoesterase, PA-phosphatase related
EC80_RS20920	COG0702	epimerase
EC80_RS20925	COG4206	TonB-dependent receptor
EC80_RS20925	COG1629	transport
EC80_RS20955	COG0463	Glycosyl transferase, family 2
EC80_RS20970	COG0066	3-isopropylmalate dehydratase activity
EC80_RS20975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EC80_RS20980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EC80_RS21035	COG0616	signal peptide processing
EC80_RS21045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EC80_RS21050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EC80_RS21060	COG4974	Belongs to the 'phage' integrase family
EC80_RS21115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EC80_RS21130	COG1538	Outer membrane efflux protein
EC80_RS21150	COG2205	protein histidine kinase activity
EC80_RS21150	COG0784	Response regulator, receiver
EC80_RS21155	COG2204	response regulator
EC80_RS21195	COG4974	Belongs to the 'phage' integrase family
EC80_RS21260	COG1335	isochorismatase
EC80_RS21265	COG1733	regulation of RNA biosynthetic process
EC80_RS21315	COG2207	Transcriptional regulator
EC80_RS21315	COG1917	Cupin 2, conserved barrel domain protein
EC80_RS21325	COG1028	Short-chain dehydrogenase reductase Sdr
EC80_RS21345	COG0463	Glycosyl transferase, family 2
EC80_RS21360	COG1971	Probably functions as a manganese efflux pump
EC80_RS21365	COG1477	protein flavinylation
EC80_RS21375	COG0037	tRNA processing
EC80_RS21390	COG4864	UPF0365 protein
EC80_RS21405	COG2910	NAD(P)H-binding
EC80_RS21410	COG2205	protein histidine kinase activity
EC80_RS21410	COG2198	Histidine kinase
EC80_RS21410	COG0784	Response regulator, receiver
EC80_RS21415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EC80_RS21425	COG4974	Belongs to the 'phage' integrase family
EC80_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
EC80_RS21565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EC80_RS21570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EC80_RS21575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EC80_RS21575	COG4651	solute:proton antiporter activity
EC80_RS21580	COG0439	Biotin carboxylase
EC80_RS21585	COG0511	ligase activity, forming carbon-carbon bonds
EC80_RS21590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EC80_RS21595	COG4977	sequence-specific DNA binding
EC80_RS21595	COG1917	Cupin 2, conserved barrel domain protein
EC80_RS21605	COG1335	isochorismatase
EC80_RS21615	COG5002	protein histidine kinase activity
EC80_RS21615	COG2205	protein histidine kinase activity
EC80_RS21615	COG0784	Response regulator, receiver
EC80_RS21620	COG2207	Transcriptional regulator
EC80_RS21625	COG0517	IMP dehydrogenase activity
EC80_RS21625	COG0516	GMP reductase activity
EC80_RS21645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EC80_RS21685	COG2873	o-acetylhomoserine
EC80_RS21745	COG2076	Multidrug Resistance protein
EC80_RS21785	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EC80_RS21795	COG0741	lytic transglycosylase activity
EC80_RS21795	COG1388	LysM domain
EC80_RS21800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EC80_RS21805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC80_RS21805	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC80_RS21815	COG1285	pathogenesis
EC80_RS21835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC80_RS21835	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EC80_RS21850	COG1115	amino acid carrier protein
EC80_RS21865	COG1509	lysine 2,3-aminomutase activity
EC80_RS21870	COG2233	PERMEase
EC80_RS21885	COG1393	Belongs to the ArsC family
EC80_RS21895	COG1629	transport
EC80_RS21905	COG2304	oxidoreductase activity
EC80_RS21915	COG0351	phosphomethylpyrimidine kinase
EC80_RS21925	COG1139	Iron-sulfur cluster binding protein
EC80_RS21930	COG0247	lactate metabolic process
EC80_RS21935	COG0602	queuosine metabolic process
EC80_RS21945	COG2832	Protein of unknown function (DUF454)
EC80_RS21950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EC80_RS21965	COG3142	Participates in the control of copper homeostasis
EC80_RS21970	COG1418	mRNA catabolic process
EC80_RS21995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EC80_RS22010	COG4771	TonB-dependent receptor
EC80_RS22050	COG3340	Belongs to the peptidase S51 family
EC80_RS22055	COG2378	regulation of single-species biofilm formation
EC80_RS22110	COG1505	serine-type exopeptidase activity
EC80_RS22140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EC80_RS22140	COG0617	tRNA 3'-terminal CCA addition
EC80_RS22140	COG0517	IMP dehydrogenase activity
EC80_RS22150	COG1126	abc transporter atp-binding protein
EC80_RS22160	COG1278	Cold shock
EC80_RS22205	COG0438	transferase activity, transferring glycosyl groups
EC80_RS22220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EC80_RS22235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EC80_RS22245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EC80_RS22275	COG0776	regulation of translation
EC80_RS22285	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EC80_RS22320	COG0632	four-way junction helicase activity
EC80_RS22325	COG0673	inositol 2-dehydrogenase activity
EC80_RS22330	COG1272	protein, Hemolysin III
EC80_RS22335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EC80_RS22335	COG1328	CTP reductase activity
EC80_RS22345	COG2814	Major facilitator Superfamily
EC80_RS22355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC80_RS22365	COG0750	zinc metalloprotease
EC80_RS22370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EC80_RS22380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EC80_RS22385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EC80_RS22395	COG1214	PFAM Peptidase M22, glycoprotease
EC80_RS22400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EC80_RS22400	COG2198	Histidine kinase
EC80_RS22400	COG2205	protein histidine kinase activity
EC80_RS22400	COG0784	Response regulator, receiver
EC80_RS22420	COG0194	GDP metabolic process
EC80_RS22425	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EC80_RS22430	COG1408	metallophosphoesterase
EC80_RS22435	COG1575	Belongs to the MenA family. Type 1 subfamily
EC80_RS22440	COG1088	dTDP-glucose 4,6-dehydratase activity
EC80_RS22445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EC80_RS22455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EC80_RS22465	COG2204	response regulator
EC80_RS22470	COG0488	(ABC) transporter
EC80_RS22505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EC80_RS22505	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EC80_RS22530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EC80_RS22540	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EC80_RS22550	COG1522	sequence-specific DNA binding
EC80_RS22575	COG0811	peptide transport
EC80_RS22585	COG0084	hydrolase, TatD family'
EC80_RS22600	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EC80_RS22605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EC80_RS22610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EC80_RS22615	COG0205	6-phosphofructokinase activity
EC80_RS22635	COG0372	Belongs to the citrate synthase family
EC80_RS22640	COG0538	isocitrate dehydrogenase activity
EC80_RS22650	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EC80_RS22660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EC80_RS22685	COG0129	dihydroxy-acid dehydratase activity
EC80_RS22705	COG2885	chlorophyll binding
EC80_RS22725	COG3681	Belongs to the UPF0597 family
EC80_RS22760	COG3119	arylsulfatase activity
EC80_RS22770	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EC80_RS22780	COG0702	epimerase
EC80_RS22785	COG4771	TonB-dependent receptor
EC80_RS22860	COG0535	radical SAM domain protein
EC80_RS22875	COG4372	Transposase
EC80_RS22880	COG2433	Pfam Transposase IS66
EC80_RS22890	COG0702	epimerase
EC80_RS22895	COG1629	transport
EC80_RS22895	COG4206	TonB-dependent receptor
EC80_RS22915	COG4771	TonB-dependent receptor
EC80_RS22945	COG1012	belongs to the aldehyde dehydrogenase family
EC80_RS22970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC80_RS22970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC80_RS22975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EC80_RS23005	COG0534	Mate efflux family protein
EC80_RS23035	COG1752	Esterase of the alpha-beta hydrolase superfamily
EC80_RS23045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EC80_RS23050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EC80_RS23055	COG0166	Belongs to the GPI family
EC80_RS23065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EC80_RS23075	COG2502	aspartate--ammonia ligase
EC80_RS23080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EC80_RS23095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EC80_RS23120	COG0860	N-Acetylmuramoyl-L-alanine amidase
EC80_RS23160	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EC80_RS23285	COG1475	DNA binding
EC80_RS23315	COG1196	nuclear chromosome segregation
EC80_RS23315	COG0741	lytic transglycosylase activity
EC80_RS23315	COG0739	heme binding
EC80_RS23410	COG4974	Belongs to the 'phage' integrase family
EC80_RS23425	COG3177	Filamentation induced by cAMP protein fic
EC80_RS23430	COG1192	Involved in chromosome partitioning
EC80_RS23585	COG2337	Toxic component of a toxin-antitoxin (TA) module