locus-tag	class	description
FOC69_RS00090	COG1196	nuclear chromosome segregation
FOC69_RS00090	COG0741	lytic transglycosylase activity
FOC69_RS00090	COG0739	heme binding
FOC69_RS00130	COG0776	regulation of translation
FOC69_RS00180	COG0110	maltose O-acetyltransferase activity
FOC69_RS00280	COG4227	nucleotidyltransferase activity
FOC69_RS00455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC69_RS00560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC69_RS00795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC69_RS00895	COG4974	Belongs to the 'phage' integrase family
FOC69_RS00900	COG0582	viral genome integration into host DNA
FOC69_RS00905	COG4974	Belongs to the 'phage' integrase family
FOC69_RS00920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC69_RS00945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOC69_RS00950	COG0107	imidazoleglycerol-phosphate synthase activity
FOC69_RS00955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC69_RS00955	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC69_RS00960	COG2884	Cell division ATP-binding protein ftsE
FOC69_RS00965	COG0527	aspartate kinase activity
FOC69_RS00970	COG0019	diaminopimelate decarboxylase activity
FOC69_RS01070	COG0156	8-amino-7-oxononanoate synthase activity
FOC69_RS01075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS01090	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC69_RS01090	COG0321	lipoyl(octanoyl) transferase activity
FOC69_RS01105	COG0592	DNA-directed DNA polymerase activity
FOC69_RS01110	COG5002	protein histidine kinase activity
FOC69_RS01110	COG2176	DNA-directed DNA polymerase activity
FOC69_RS01120	COG0497	DNA recombination
FOC69_RS01145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC69_RS01170	COG2172	sigma factor antagonist activity
FOC69_RS01185	COG5002	protein histidine kinase activity
FOC69_RS01250	COG0167	dihydroorotate dehydrogenase activity
FOC69_RS01255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC69_RS01285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOC69_RS01335	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOC69_RS01355	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS01360	COG1045	serine acetyltransferase
FOC69_RS01370	COG1216	Glycosyl transferase, family 2
FOC69_RS01390	COG1215	transferase activity, transferring glycosyl groups
FOC69_RS01395	COG1216	Glycosyl transferase, family 2
FOC69_RS01400	COG1216	Glycosyl transferase, family 2
FOC69_RS01450	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC69_RS01490	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC69_RS01510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC69_RS01520	COG0573	inorganic phosphate transmembrane transporter activity
FOC69_RS01525	COG0581	inorganic phosphate transmembrane transporter activity
FOC69_RS01530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC69_RS01535	COG0704	Plays a role in the regulation of phosphate uptake
FOC69_RS01545	COG0778	Nitroreductase
FOC69_RS01550	COG1295	ribonuclease BN
FOC69_RS01565	COG4948	Mandelate Racemase Muconate Lactonizing
FOC69_RS01575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC69_RS01580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC69_RS01605	COG5002	protein histidine kinase activity
FOC69_RS01610	COG0745	RESPONSE REGULATOR receiver
FOC69_RS01655	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FOC69_RS01675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC69_RS01685	COG0058	SHG alpha-glucan phosphorylase activity
FOC69_RS01695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC69_RS01705	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC69_RS01710	COG1177	transmembrane transport
FOC69_RS01720	COG0724	RNA recognition motif
FOC69_RS01735	COG0228	four-way junction DNA binding
FOC69_RS01750	COG1690	Belongs to the RtcB family
FOC69_RS01755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOC69_RS01775	COG0745	RESPONSE REGULATOR receiver
FOC69_RS01780	COG5002	protein histidine kinase activity
FOC69_RS01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS01790	COG2198	Histidine kinase
FOC69_RS01790	COG0784	Response regulator, receiver
FOC69_RS01790	COG2205	protein histidine kinase activity
FOC69_RS01800	COG1733	regulation of RNA biosynthetic process
FOC69_RS01810	COG1609	Transcriptional regulator
FOC69_RS01825	COG3610	response to peptide
FOC69_RS01860	COG4771	TonB-dependent receptor
FOC69_RS01890	COG1566	PFAM secretion protein HlyD family protein
FOC69_RS01895	COG2814	Major facilitator Superfamily
FOC69_RS01910	COG4771	TonB-dependent receptor
FOC69_RS01920	COG1858	cytochrome C peroxidase
FOC69_RS01945	COG0716	FMN binding
FOC69_RS01950	COG0138	bifunctional purine biosynthesis protein purh
FOC69_RS01960	COG2197	response regulator
FOC69_RS01965	COG0110	maltose O-acetyltransferase activity
FOC69_RS01975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC69_RS01980	COG3292	Two component regulator propeller
FOC69_RS01980	COG2205	protein histidine kinase activity
FOC69_RS01980	COG0745	RESPONSE REGULATOR receiver
FOC69_RS01990	COG0252	asparaginase activity
FOC69_RS01995	COG0159	tryptophan synthase activity
FOC69_RS02000	COG0135	phosphoribosylanthranilate isomerase activity
FOC69_RS02005	COG0134	indole-3-glycerol-phosphate synthase activity
FOC69_RS02020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC69_RS02025	COG0133	tryptophan synthase activity
FOC69_RS02030	COG1979	alcohol dehydrogenase
FOC69_RS02040	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC69_RS02070	COG3275	phosphorelay sensor kinase activity
FOC69_RS02085	COG0367	asparagine synthase
FOC69_RS02095	COG0069	glutamate synthase activity
FOC69_RS02095	COG0067	glutamate synthase
FOC69_RS02095	COG0070	glutamate synthase
FOC69_RS02105	COG0505	Belongs to the CarA family
FOC69_RS02110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC69_RS02145	COG1131	(ABC) transporter
FOC69_RS02150	COG0842	Transport permease protein
FOC69_RS02155	COG0842	Transport permease protein
FOC69_RS02175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC69_RS02190	COG2949	membrane
FOC69_RS02195	COG0556	nucleotide-excision repair
FOC69_RS02200	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOC69_RS02230	COG3942	CHAP domain
FOC69_RS02230	COG1388	LysM domain
FOC69_RS02240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC69_RS02255	COG1695	Transcriptional regulator
FOC69_RS02265	COG0110	maltose O-acetyltransferase activity
FOC69_RS02280	COG0823	Involved in the tonB-independent uptake of proteins
FOC69_RS02280	COG1506	peptidase
FOC69_RS02285	COG0534	Mate efflux family protein
FOC69_RS02295	COG0504	CTP synthase activity
FOC69_RS02320	COG4656	Part of a membrane complex involved in electron transport
FOC69_RS02325	COG4658	electron transport chain
FOC69_RS02330	COG4659	FMN binding
FOC69_RS02335	COG4660	Part of a membrane complex involved in electron transport
FOC69_RS02340	COG4657	Part of a membrane complex involved in electron transport
FOC69_RS02345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC69_RS02360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOC69_RS02365	COG0305	Participates in initiation and elongation during chromosome replication
FOC69_RS02395	COG2244	polysaccharide biosynthetic process
FOC69_RS02425	COG1216	Glycosyl transferase, family 2
FOC69_RS02435	COG0582	viral genome integration into host DNA
FOC69_RS02490	COG1442	glycosyl transferase family 8
FOC69_RS02490	COG1216	Glycosyl transferase, family 2
FOC69_RS02495	COG1086	Polysaccharide biosynthesis protein
FOC69_RS02505	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC69_RS02515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS02520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS02525	COG0072	phenylalanine-tRNA ligase activity
FOC69_RS02525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC69_RS02530	COG0217	transcriptional regulatory protein
FOC69_RS02545	COG1914	H( )-stimulated, divalent metal cation uptake system
FOC69_RS02550	COG0708	Exodeoxyribonuclease III
FOC69_RS02570	COG0481	GTPase activity
FOC69_RS02580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FOC69_RS02605	COG0024	Methionine aminopeptidase
FOC69_RS02620	COG0564	pseudouridine synthase activity
FOC69_RS02625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC69_RS02630	COG0574	Belongs to the PEP-utilizing enzyme family
FOC69_RS02630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC69_RS02645	COG0352	thiamine-phosphate diphosphorylase activity
FOC69_RS02650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC69_RS02665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOC69_RS02670	COG2022	thiamine diphosphate biosynthetic process
FOC69_RS02675	COG0352	thiamine-phosphate diphosphorylase activity
FOC69_RS02740	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC69_RS02750	COG0305	Participates in initiation and elongation during chromosome replication
FOC69_RS02850	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FOC69_RS02875	COG4774	siderophore transport
FOC69_RS02885	COG4771	TonB-dependent receptor
FOC69_RS02900	COG2966	Psort location CytoplasmicMembrane, score
FOC69_RS02915	COG1797	cobyrinic acid a,c-diamide synthase activity
FOC69_RS02920	COG2096	Adenosyltransferase
FOC69_RS02965	COG1492	cobalamin metabolic process
FOC69_RS02975	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FOC69_RS02990	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOC69_RS03005	COG4946	Tricorn protease homolog
FOC69_RS03005	COG0793	Belongs to the peptidase S41A family
FOC69_RS03020	COG0442	prolyl-tRNA aminoacylation
FOC69_RS03035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC69_RS03040	COG1546	Belongs to the CinA family
FOC69_RS03040	COG1058	Belongs to the CinA family
FOC69_RS03045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC69_RS03050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC69_RS03060	COG0552	protein localization to endoplasmic reticulum
FOC69_RS03065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC69_RS03075	COG1652	LysM domain
FOC69_RS03080	COG0714	Associated with various cellular activities
FOC69_RS03095	COG2304	oxidoreductase activity
FOC69_RS03140	COG0542	response to heat
FOC69_RS03145	COG0326	Molecular chaperone. Has ATPase activity
FOC69_RS03150	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC69_RS03175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC69_RS03180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC69_RS03185	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC69_RS03190	COG0167	dihydroorotate dehydrogenase activity
FOC69_RS03195	COG0543	2 iron, 2 sulfur cluster binding
FOC69_RS03210	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC69_RS03240	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC69_RS03260	COG0577	efflux transmembrane transporter activity
FOC69_RS03260	COG1136	(ABC) transporter
FOC69_RS03285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC69_RS03290	COG1597	lipid kinase activity
FOC69_RS03295	COG0156	8-amino-7-oxononanoate synthase activity
FOC69_RS03305	COG1136	(ABC) transporter
FOC69_RS03305	COG0577	efflux transmembrane transporter activity
FOC69_RS03350	COG2204	response regulator
FOC69_RS03390	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC69_RS03395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC69_RS03415	COG0560	Phosphoserine phosphatase
FOC69_RS03415	COG3830	Belongs to the UPF0237 family
FOC69_RS03420	COG0513	Belongs to the DEAD box helicase family
FOC69_RS03450	COG1904	glucuronate isomerase
FOC69_RS03460	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC69_RS03510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC69_RS03525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC69_RS03535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC69_RS03555	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC69_RS03560	COG1858	cytochrome C peroxidase
FOC69_RS03565	COG0724	RNA recognition motif
FOC69_RS03570	COG0450	alkyl hydroperoxide reductase
FOC69_RS03575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC69_RS03575	COG3153	acetyltransferase
FOC69_RS03585	COG2814	Major facilitator Superfamily
FOC69_RS03585	COG0477	Major facilitator Superfamily
FOC69_RS03595	COG1070	Carbohydrate kinase
FOC69_RS03605	COG0351	phosphomethylpyrimidine kinase
FOC69_RS03610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC69_RS03615	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC69_RS03620	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC69_RS03640	COG0671	phosphoesterase, PA-phosphatase related
FOC69_RS03660	COG2223	nitrite transmembrane transporter activity
FOC69_RS03670	COG0673	inositol 2-dehydrogenase activity
FOC69_RS03690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC69_RS03695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC69_RS03705	COG2135	peptidase activity
FOC69_RS03725	COG2205	protein histidine kinase activity
FOC69_RS03730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC69_RS03745	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOC69_RS03755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC69_RS03775	COG1629	transport
FOC69_RS03775	COG4206	TonB-dependent receptor
FOC69_RS03785	COG2837	iron assimilation
FOC69_RS03810	COG2431	L-lysine efflux transmembrane transporter activity
FOC69_RS03820	COG0540	Belongs to the ATCase OTCase family
FOC69_RS03825	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOC69_RS03840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOC69_RS03850	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC69_RS03855	COG2202	Pas domain
FOC69_RS03855	COG2205	protein histidine kinase activity
FOC69_RS03865	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC69_RS03880	COG1064	alcohol dehydrogenase
FOC69_RS03885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC69_RS03900	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOC69_RS03905	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC69_RS03940	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC69_RS03945	COG1120	ATPase activity
FOC69_RS03975	COG5002	protein histidine kinase activity
FOC69_RS03980	COG0745	RESPONSE REGULATOR receiver
FOC69_RS04000	COG3118	belongs to the thioredoxin family
FOC69_RS04005	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC69_RS04010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOC69_RS04015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC69_RS04020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC69_RS04025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC69_RS04030	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC69_RS04035	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC69_RS04045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC69_RS04055	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC69_RS04080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC69_RS04095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC69_RS04100	COG2755	lipolytic protein G-D-S-L family
FOC69_RS04100	COG0657	acetylesterase activity
FOC69_RS04105	COG0167	dihydroorotate dehydrogenase activity
FOC69_RS04115	COG0534	Mate efflux family protein
FOC69_RS04125	COG1136	(ABC) transporter
FOC69_RS04135	COG0577	efflux transmembrane transporter activity
FOC69_RS04135	COG1136	(ABC) transporter
FOC69_RS04155	COG2204	response regulator
FOC69_RS04170	COG1151	hydroxylamine reductase activity
FOC69_RS04180	COG3263	regulation of cellular component size
FOC69_RS04185	COG1022	Amp-dependent synthetase and ligase
FOC69_RS04205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOC69_RS04295	COG4974	Belongs to the 'phage' integrase family
FOC69_RS04530	COG1475	DNA binding
FOC69_RS04550	COG1192	Involved in chromosome partitioning
FOC69_RS04600	COG0542	response to heat
FOC69_RS04665	COG3209	COG3209 Rhs family protein
FOC69_RS04675	COG3209	COG3209 Rhs family protein
FOC69_RS04775	COG0739	heme binding
FOC69_RS04775	COG1196	nuclear chromosome segregation
FOC69_RS04775	COG0741	lytic transglycosylase activity
FOC69_RS04835	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC69_RS05095	COG4974	Belongs to the 'phage' integrase family
FOC69_RS05105	COG4206	TonB-dependent receptor
FOC69_RS05105	COG1629	transport
FOC69_RS05120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS05135	COG0745	RESPONSE REGULATOR receiver
FOC69_RS05140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS05180	COG1475	DNA binding
FOC69_RS05185	COG3969	phosphoadenosine phosphosulfate
FOC69_RS05220	COG0681	Belongs to the peptidase S26 family
FOC69_RS05230	COG3250	beta-galactosidase activity
FOC69_RS05235	COG3119	arylsulfatase activity
FOC69_RS05245	COG4771	TonB-dependent receptor
FOC69_RS05285	COG1678	Uncharacterized ACR, COG1678
FOC69_RS05300	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC69_RS05310	COG1755	Isoprenylcysteine carboxyl methyltransferase
FOC69_RS05320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC69_RS05335	COG1136	(ABC) transporter
FOC69_RS05350	COG2204	response regulator
FOC69_RS05355	COG3852	Histidine kinase
FOC69_RS05380	COG0321	lipoyl(octanoyl) transferase activity
FOC69_RS05390	COG2217	Heavy metal translocating P-type atpase
FOC69_RS05420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC69_RS05425	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC69_RS05425	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC69_RS05430	COG0778	Nitroreductase
FOC69_RS05440	COG1739	Uncharacterized protein family UPF0029
FOC69_RS05445	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC69_RS05455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC69_RS05460	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOC69_RS05485	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC69_RS05490	COG1805	sodium ion transport
FOC69_RS05495	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC69_RS05525	COG1215	transferase activity, transferring glycosyl groups
FOC69_RS05540	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC69_RS05845	COG2244	polysaccharide biosynthetic process
FOC69_RS05855	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS05875	COG4999	Histidine kinase
FOC69_RS05875	COG2205	protein histidine kinase activity
FOC69_RS05875	COG3437	response regulator, receiver
FOC69_RS05875	COG3850	Histidine kinase
FOC69_RS05895	COG0488	(ABC) transporter
FOC69_RS06120	COG2204	response regulator
FOC69_RS06125	COG0784	Response regulator, receiver
FOC69_RS06125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS06125	COG2198	Histidine kinase
FOC69_RS06125	COG2205	protein histidine kinase activity
FOC69_RS06135	COG1045	serine acetyltransferase
FOC69_RS06140	COG2918	glutathione biosynthetic process
FOC69_RS06140	COG0189	ligase activity
FOC69_RS06145	COG0534	Mate efflux family protein
FOC69_RS06155	COG0798	PFAM Bile acid sodium symporter
FOC69_RS06160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC69_RS06205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC69_RS06205	COG0551	DNA topoisomerase type I activity
FOC69_RS06260	COG4974	Belongs to the 'phage' integrase family
FOC69_RS06460	COG2207	Transcriptional regulator
FOC69_RS06475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC69_RS06475	COG0551	DNA topoisomerase type I activity
FOC69_RS06555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC69_RS06560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOC69_RS06605	COG4771	TonB-dependent receptor
FOC69_RS06630	COG4771	TonB-dependent receptor
FOC69_RS06635	COG2814	Major facilitator Superfamily
FOC69_RS06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC69_RS06655	COG0656	L-ascorbic acid biosynthetic process
FOC69_RS06660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC69_RS06690	COG0697	spore germination
FOC69_RS06700	COG2885	chlorophyll binding
FOC69_RS06700	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC69_RS06705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC69_RS06715	COG1629	transport
FOC69_RS06715	COG4206	TonB-dependent receptor
FOC69_RS06725	COG1595	DNA-templated transcription, initiation
FOC69_RS06730	COG1704	LemA family
FOC69_RS06735	COG0501	Belongs to the peptidase M48B family
FOC69_RS06760	COG3250	beta-galactosidase activity
FOC69_RS06765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC69_RS06770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC69_RS06780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC69_RS06795	COG3831	ATPase activity
FOC69_RS06795	COG4884	unkown
FOC69_RS06830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS06835	COG1136	(ABC) transporter
FOC69_RS06840	COG0577	efflux transmembrane transporter activity
FOC69_RS06840	COG1136	(ABC) transporter
FOC69_RS06850	COG3279	Response regulator of the LytR AlgR family
FOC69_RS06880	COG1742	UPF0060 membrane protein
FOC69_RS06925	COG0363	glucosamine-6-phosphate deaminase activity
FOC69_RS06930	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC69_RS06935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC69_RS06940	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FOC69_RS06980	COG0784	Response regulator, receiver
FOC69_RS06980	COG2205	protein histidine kinase activity
FOC69_RS06985	COG1538	Outer membrane efflux protein
FOC69_RS07000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC69_RS07035	COG4974	Belongs to the 'phage' integrase family
FOC69_RS07070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS07075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS07085	COG1091	dTDP-4-dehydrorhamnose reductase activity
FOC69_RS07095	COG1086	Polysaccharide biosynthesis protein
FOC69_RS07160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOC69_RS07165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS07170	COG0318	PFAM AMP-dependent synthetase and ligase
FOC69_RS07180	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FOC69_RS07190	COG0534	Mate efflux family protein
FOC69_RS07220	COG4771	TonB-dependent receptor
FOC69_RS07235	COG0534	Mate efflux family protein
FOC69_RS07260	COG4771	TonB-dependent receptor
FOC69_RS07275	COG1956	GAF domain-containing protein
FOC69_RS07280	COG0737	Belongs to the 5'-nucleotidase family
FOC69_RS07290	COG2183	response to ionizing radiation
FOC69_RS07405	COG2885	chlorophyll binding
FOC69_RS07460	COG1595	DNA-templated transcription, initiation
FOC69_RS07465	COG0488	(ABC) transporter
FOC69_RS07470	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC69_RS07475	COG0484	heat shock protein binding
FOC69_RS07485	COG0702	epimerase
FOC69_RS07490	COG4771	TonB-dependent receptor
FOC69_RS07495	COG3250	beta-galactosidase activity
FOC69_RS07500	COG3537	Alpha-1,2-mannosidase
FOC69_RS07505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS07515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS07535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS07550	COG1629	transport
FOC69_RS07550	COG4206	TonB-dependent receptor
FOC69_RS07555	COG1629	transport
FOC69_RS07555	COG4206	TonB-dependent receptor
FOC69_RS07560	COG0702	epimerase
FOC69_RS07565	COG0702	epimerase
FOC69_RS07570	COG4771	TonB-dependent receptor
FOC69_RS07580	COG0702	epimerase
FOC69_RS07585	COG1629	transport
FOC69_RS07595	COG0702	epimerase
FOC69_RS07600	COG1629	transport
FOC69_RS07615	COG0702	epimerase
FOC69_RS07620	COG1629	transport
FOC69_RS07625	COG2731	YhcH YjgK YiaL family protein
FOC69_RS07630	COG2271	Major facilitator Superfamily
FOC69_RS07640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC69_RS07645	COG1940	carbohydrate kinase activity
FOC69_RS07685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC69_RS07695	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC69_RS07695	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC69_RS07695	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC69_RS07695	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOC69_RS07700	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOC69_RS07705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC69_RS07715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOC69_RS07720	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC69_RS07725	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC69_RS07730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC69_RS07745	COG0242	peptide deformylase activity
FOC69_RS07750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC69_RS07775	COG4974	Belongs to the 'phage' integrase family
FOC69_RS07795	COG2885	chlorophyll binding
FOC69_RS07815	COG0175	sulfate reduction
FOC69_RS07820	COG0529	Catalyzes the synthesis of activated sulfate
FOC69_RS07825	COG0471	metal ion transport
FOC69_RS07825	COG3273	potassium ion transport
FOC69_RS07835	COG3250	beta-galactosidase activity
FOC69_RS07845	COG4221	oxidoreductase activity
FOC69_RS07850	COG0513	Belongs to the DEAD box helicase family
FOC69_RS07870	COG1482	cell wall glycoprotein biosynthetic process
FOC69_RS07885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC69_RS07890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOC69_RS07895	COG0698	ribose 5-phosphate isomerase
FOC69_RS07940	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC69_RS07945	COG0673	inositol 2-dehydrogenase activity
FOC69_RS07970	COG0590	tRNA wobble adenosine to inosine editing
FOC69_RS07990	COG2264	protein methyltransferase activity
FOC69_RS07995	COG0716	FMN binding
FOC69_RS08000	COG0022	dehydrogenase e1 component
FOC69_RS08005	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC69_RS08040	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FOC69_RS08045	COG2226	methyltransferase
FOC69_RS08055	COG0511	ligase activity, forming carbon-carbon bonds
FOC69_RS08060	COG0439	Biotin carboxylase
FOC69_RS08065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC69_RS08080	COG1620	l-lactate permease
FOC69_RS08090	COG4771	TonB-dependent receptor
FOC69_RS08120	COG1252	NADH dehydrogenase
FOC69_RS08125	COG1136	(ABC) transporter
FOC69_RS08125	COG0577	efflux transmembrane transporter activity
FOC69_RS08130	COG1136	(ABC) transporter
FOC69_RS08130	COG0577	efflux transmembrane transporter activity
FOC69_RS08140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS08155	COG3852	Histidine kinase
FOC69_RS08165	COG1215	transferase activity, transferring glycosyl groups
FOC69_RS08170	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC69_RS08175	COG0436	Aminotransferase
FOC69_RS08200	COG0488	(ABC) transporter
FOC69_RS08225	COG0745	RESPONSE REGULATOR receiver
FOC69_RS08245	COG4206	TonB-dependent receptor
FOC69_RS08310	COG0629	single-stranded DNA binding
FOC69_RS08315	COG3119	arylsulfatase activity
FOC69_RS08330	COG1530	ribonuclease E activity
FOC69_RS08335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS08340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS08350	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS08360	COG1216	Glycosyl transferase, family 2
FOC69_RS08375	COG1215	transferase activity, transferring glycosyl groups
FOC69_RS08390	COG0656	L-ascorbic acid biosynthetic process
FOC69_RS08400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS08495	COG4191	Histidine kinase
FOC69_RS08500	COG2204	response regulator
FOC69_RS08510	COG2205	protein histidine kinase activity
FOC69_RS08510	COG0784	Response regulator, receiver
FOC69_RS08530	COG1136	(ABC) transporter
FOC69_RS08540	COG0577	efflux transmembrane transporter activity
FOC69_RS08545	COG1136	(ABC) transporter
FOC69_RS08560	COG2207	Transcriptional regulator
FOC69_RS08560	COG0662	Cupin 2, conserved barrel domain protein
FOC69_RS08570	COG0577	efflux transmembrane transporter activity
FOC69_RS08570	COG1136	(ABC) transporter
FOC69_RS08580	COG0577	efflux transmembrane transporter activity
FOC69_RS08590	COG0577	efflux transmembrane transporter activity
FOC69_RS08600	COG0577	efflux transmembrane transporter activity
FOC69_RS08610	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC69_RS08610	COG1388	LysM domain
FOC69_RS08615	COG0295	cytidine deaminase activity
FOC69_RS08620	COG0662	Cupin 2, conserved barrel domain protein
FOC69_RS08620	COG2207	Transcriptional regulator
FOC69_RS08625	COG3059	membrane
FOC69_RS08630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC69_RS08635	COG0488	(ABC) transporter
FOC69_RS08650	COG3345	alpha-galactosidase
FOC69_RS08665	COG1629	transport
FOC69_RS08680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC69_RS08695	COG0686	Belongs to the AlaDH PNT family
FOC69_RS08720	COG1595	DNA-templated transcription, initiation
FOC69_RS08735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOC69_RS08745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC69_RS08770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS08770	COG0784	Response regulator, receiver
FOC69_RS08770	COG2205	protein histidine kinase activity
FOC69_RS08770	COG2198	Histidine kinase
FOC69_RS08775	COG2204	response regulator
FOC69_RS08895	COG0358	DNA primase activity
FOC69_RS08990	COG1388	LysM domain
FOC69_RS08990	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC69_RS09060	COG0741	lytic transglycosylase activity
FOC69_RS09060	COG0739	heme binding
FOC69_RS09060	COG1196	nuclear chromosome segregation
FOC69_RS09075	COG3279	Response regulator of the LytR AlgR family
FOC69_RS09105	COG0629	single-stranded DNA binding
FOC69_RS09120	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOC69_RS09140	COG1192	Involved in chromosome partitioning
FOC69_RS09155	COG1475	DNA binding
FOC69_RS09295	COG0202	RNA polymerase activity
FOC69_RS09360	COG4974	Belongs to the 'phage' integrase family
FOC69_RS09380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC69_RS09395	COG1741	Belongs to the pirin family
FOC69_RS09400	COG0259	pyridoxamine-phosphate oxidase activity
FOC69_RS09415	COG0346	lactoylglutathione lyase activity
FOC69_RS09430	COG0471	metal ion transport
FOC69_RS09430	COG0490	domain, Protein
FOC69_RS09450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC69_RS09460	COG0463	Glycosyl transferase, family 2
FOC69_RS09460	COG1216	Glycosyl transferase, family 2
FOC69_RS09465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC69_RS09495	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC69_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS09520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC69_RS09525	COG1086	Polysaccharide biosynthesis protein
FOC69_RS09580	COG1918	ferrous iron import across plasma membrane
FOC69_RS09580	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC69_RS09590	COG2373	Large extracellular alpha-helical protein
FOC69_RS09595	COG4953	penicillin-binding protein 1C
FOC69_RS09600	COG2814	Major facilitator Superfamily
FOC69_RS09635	COG2873	o-acetylhomoserine
FOC69_RS09660	COG0501	Belongs to the peptidase M48B family
FOC69_RS09665	COG1253	flavin adenine dinucleotide binding
FOC69_RS09690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOC69_RS09690	COG2755	lipolytic protein G-D-S-L family
FOC69_RS09710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC69_RS09735	COG0783	Belongs to the Dps family
FOC69_RS09740	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC69_RS09770	COG4771	TonB-dependent receptor
FOC69_RS09785	COG1082	Xylose isomerase domain protein TIM barrel
FOC69_RS09800	COG4948	Mandelate Racemase Muconate Lactonizing
FOC69_RS09805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC69_RS09815	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC69_RS09820	COG1169	isochorismate synthase
FOC69_RS09825	COG0561	phosphatase activity
FOC69_RS09830	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC69_RS09845	COG1280	lysine exporter protein (LysE YggA)
FOC69_RS09850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC69_RS09850	COG4651	solute:proton antiporter activity
FOC69_RS09930	COG2207	Transcriptional regulator
FOC69_RS09930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOC69_RS09940	COG1629	transport
FOC69_RS09940	COG4206	TonB-dependent receptor
FOC69_RS09950	COG2855	membrane
FOC69_RS09955	COG2217	Heavy metal translocating P-type atpase
FOC69_RS09965	COG2885	chlorophyll binding
FOC69_RS09970	COG3189	MarR family transcriptional regulator
FOC69_RS09975	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC69_RS09980	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC69_RS09985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC69_RS09990	COG0784	Response regulator, receiver
FOC69_RS09990	COG2205	protein histidine kinase activity
FOC69_RS10000	COG1193	negative regulation of DNA recombination
FOC69_RS10005	COG0598	Magnesium transport protein CorA
FOC69_RS10010	COG1760	l-serine dehydratase
FOC69_RS10040	COG3634	alkyl hydroperoxide reductase activity
FOC69_RS10050	COG1408	metallophosphoesterase
FOC69_RS10060	COG1629	transport
FOC69_RS10060	COG4206	TonB-dependent receptor
FOC69_RS10080	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC69_RS10095	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC69_RS10100	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FOC69_RS10105	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC69_RS10115	COG0443	Heat shock 70 kDa protein
FOC69_RS10135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC69_RS10155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC69_RS10170	COG1595	DNA-templated transcription, initiation
FOC69_RS10185	COG2855	membrane
FOC69_RS10190	COG0583	DNA-binding transcription factor activity
FOC69_RS10200	COG0542	response to heat
FOC69_RS10215	COG0237	dephospho-CoA kinase activity
FOC69_RS10225	COG1862	Preprotein translocase
FOC69_RS10230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC69_RS10240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOC69_RS10245	COG0193	aminoacyl-tRNA hydrolase activity
FOC69_RS10250	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC69_RS10270	COG1082	Xylose isomerase domain protein TIM barrel
FOC69_RS10275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC69_RS10285	COG0148	phosphopyruvate hydratase activity
FOC69_RS10300	COG3011	Protein conserved in bacteria
FOC69_RS10310	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
FOC69_RS10330	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC69_RS10345	COG0564	pseudouridine synthase activity
FOC69_RS10350	COG0454	-acetyltransferase
FOC69_RS10375	COG0784	Response regulator, receiver
FOC69_RS10375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS10375	COG2198	Histidine kinase
FOC69_RS10375	COG2205	protein histidine kinase activity
FOC69_RS10390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC69_RS10400	COG0656	L-ascorbic acid biosynthetic process
FOC69_RS10435	COG0582	viral genome integration into host DNA
FOC69_RS10455	COG1288	antiporter activity
FOC69_RS10475	COG2207	Transcriptional regulator
FOC69_RS10490	COG2706	6-phosphogluconolactonase activity
FOC69_RS10515	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC69_RS10520	COG0563	adenylate kinase activity
FOC69_RS10530	COG4771	TonB-dependent receptor
FOC69_RS10545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS10555	COG1216	Glycosyl transferase, family 2
FOC69_RS10575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC69_RS10590	COG0110	maltose O-acetyltransferase activity
FOC69_RS10605	COG2030	dehydratase
FOC69_RS10635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC69_RS10675	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOC69_RS10685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC69_RS10695	COG1253	flavin adenine dinucleotide binding
FOC69_RS10715	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOC69_RS10725	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FOC69_RS10745	COG3119	arylsulfatase activity
FOC69_RS10750	COG3119	arylsulfatase activity
FOC69_RS10755	COG0702	epimerase
FOC69_RS10760	COG4771	TonB-dependent receptor
FOC69_RS10775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC69_RS10790	COG4771	TonB-dependent receptor
FOC69_RS10805	COG0784	Response regulator, receiver
FOC69_RS10805	COG2198	Histidine kinase
FOC69_RS10805	COG2205	protein histidine kinase activity
FOC69_RS10810	COG0525	valine-tRNA ligase activity
FOC69_RS10820	COG3956	TIGRFAM MazG family protein
FOC69_RS10835	COG1595	DNA-templated transcription, initiation
FOC69_RS10870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS10875	COG0492	ferredoxin-NADP+ reductase activity
FOC69_RS10885	COG1674	ftsk spoiiie
FOC69_RS10900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC69_RS10905	COG2211	Major facilitator Superfamily
FOC69_RS10925	COG1136	(ABC) transporter
FOC69_RS10935	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC69_RS10940	COG1597	lipid kinase activity
FOC69_RS10945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOC69_RS10950	COG0612	Peptidase, M16
FOC69_RS10960	COG1131	(ABC) transporter
FOC69_RS10965	COG0791	NLP P60 protein
FOC69_RS10970	COG0546	phosphoglycolate phosphatase activity
FOC69_RS10975	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOC69_RS10980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOC69_RS10985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC69_RS10995	COG0543	2 iron, 2 sulfur cluster binding
FOC69_RS11000	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC69_RS11005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC69_RS11010	COG0297	glycogen (starch) synthase activity
FOC69_RS11065	COG0626	cystathionine gamma-synthase activity
FOC69_RS11070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC69_RS11075	COG0561	phosphatase activity
FOC69_RS11080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC69_RS11090	COG0009	L-threonylcarbamoyladenylate synthase
FOC69_RS11100	COG0363	glucosamine-6-phosphate deaminase activity
FOC69_RS11110	COG1242	4 iron, 4 sulfur cluster binding
FOC69_RS11130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC69_RS11140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC69_RS11150	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOC69_RS11155	COG4206	TonB-dependent receptor
FOC69_RS11155	COG1629	transport
FOC69_RS11165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC69_RS11165	COG0519	Catalyzes the synthesis of GMP from XMP
FOC69_RS11170	COG1970	mechanosensitive ion channel activity
FOC69_RS11180	COG0339	signal peptide processing
FOC69_RS11190	COG2131	deaminase
FOC69_RS11195	COG0793	Belongs to the peptidase S41A family
FOC69_RS11200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC69_RS11240	COG0673	inositol 2-dehydrogenase activity
FOC69_RS11250	COG1629	transport
FOC69_RS11250	COG4206	TonB-dependent receptor
FOC69_RS11260	COG4771	TonB-dependent receptor
FOC69_RS11270	COG4206	TonB-dependent receptor
FOC69_RS11270	COG1629	transport
FOC69_RS11285	COG4206	TonB-dependent receptor
FOC69_RS11285	COG1629	transport
FOC69_RS11290	COG0702	epimerase
FOC69_RS11315	COG2814	Major facilitator Superfamily
FOC69_RS11320	COG0457	Tetratricopeptide repeat
FOC69_RS11340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC69_RS11345	COG3250	beta-galactosidase activity
FOC69_RS11365	COG0101	tRNA pseudouridine synthase activity
FOC69_RS11375	COG5434	Belongs to the glycosyl hydrolase 28 family
FOC69_RS11385	COG2268	Band 7 protein
FOC69_RS11395	COG1702	phosphate starvation-inducible protein PhoH
FOC69_RS11400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOC69_RS11405	COG2226	methyltransferase
FOC69_RS11410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC69_RS11425	COG1704	LemA family
FOC69_RS11435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC69_RS11440	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC69_RS11445	COG0284	orotidine-5'-phosphate decarboxylase activity
FOC69_RS11450	COG1078	dGTPase activity
FOC69_RS11455	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC69_RS11460	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOC69_RS11460	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC69_RS11465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC69_RS11475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC69_RS11490	COG4585	Histidine kinase
FOC69_RS11510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC69_RS11515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC69_RS11520	COG0805	protein transport
FOC69_RS11540	COG2271	Major facilitator Superfamily
FOC69_RS11545	COG0745	RESPONSE REGULATOR receiver
FOC69_RS11545	COG3292	Two component regulator propeller
FOC69_RS11545	COG2205	protein histidine kinase activity
FOC69_RS11550	COG1629	transport
FOC69_RS11560	COG3119	arylsulfatase activity
FOC69_RS11575	COG3119	arylsulfatase activity
FOC69_RS11580	COG0546	phosphoglycolate phosphatase activity
FOC69_RS11595	COG1073	alpha beta
FOC69_RS11600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC69_RS11605	COG0569	domain protein
FOC69_RS11610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC69_RS11620	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC69_RS11625	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC69_RS11630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC69_RS11630	COG0649	NAD binding
FOC69_RS11635	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC69_RS11645	COG0839	Belongs to the complex I subunit 6 family
FOC69_RS11650	COG0713	ATP synthesis coupled electron transport
FOC69_RS11655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC69_RS11660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC69_RS11670	COG2205	protein histidine kinase activity
FOC69_RS11670	COG5002	protein histidine kinase activity
FOC69_RS11670	COG0784	Response regulator, receiver
FOC69_RS11675	COG1404	Belongs to the peptidase S8 family
FOC69_RS11675	COG4412	M6 family metalloprotease domain protein
FOC69_RS11705	COG2942	2-epimerase
FOC69_RS11710	COG2211	Major facilitator Superfamily
FOC69_RS11715	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC69_RS11720	COG4124	Belongs to the glycosyl hydrolase 26 family
FOC69_RS11725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOC69_RS11735	COG5012	cobalamin binding
FOC69_RS11775	COG0702	epimerase
FOC69_RS11780	COG4771	TonB-dependent receptor
FOC69_RS11785	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC69_RS11790	COG0667	Aldo Keto reductase
FOC69_RS11795	COG1373	ATPase (AAA superfamily
FOC69_RS11815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC69_RS11840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS11850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS11865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC69_RS11885	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS11910	COG2244	polysaccharide biosynthetic process
FOC69_RS11960	COG0662	Cupin 2, conserved barrel domain protein
FOC69_RS11960	COG2207	Transcriptional regulator
FOC69_RS11965	COG0668	transmembrane transport
FOC69_RS12020	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC69_RS12030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC69_RS12035	COG2239	Acts as a magnesium transporter
FOC69_RS12050	COG0799	negative regulation of ribosome biogenesis
FOC69_RS12055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC69_RS12070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC69_RS12075	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC69_RS12080	COG1192	Involved in chromosome partitioning
FOC69_RS12085	COG1475	DNA binding
FOC69_RS12095	COG3942	CHAP domain
FOC69_RS12095	COG1388	LysM domain
FOC69_RS12100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC69_RS12110	COG0739	heme binding
FOC69_RS12135	COG2814	Major facilitator Superfamily
FOC69_RS12140	COG3537	Alpha-1,2-mannosidase
FOC69_RS12155	COG3537	Alpha-1,2-mannosidase
FOC69_RS12165	COG4771	TonB-dependent receptor
FOC69_RS12190	COG0742	ribosomal rna small subunit methyltransferase
FOC69_RS12195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC69_RS12210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOC69_RS12230	COG1566	PFAM secretion protein HlyD family protein
FOC69_RS12245	COG0784	Response regulator, receiver
FOC69_RS12245	COG2205	protein histidine kinase activity
FOC69_RS12260	COG3250	beta-galactosidase activity
FOC69_RS12280	COG1629	transport
FOC69_RS12305	COG2234	aminopeptidase activity
FOC69_RS12315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC69_RS12320	COG0802	atpase or kinase
FOC69_RS12335	COG0714	Associated with various cellular activities
FOC69_RS12365	COG2205	protein histidine kinase activity
FOC69_RS12400	COG1136	(ABC) transporter
FOC69_RS12400	COG0577	efflux transmembrane transporter activity
FOC69_RS12420	COG3118	belongs to the thioredoxin family
FOC69_RS12430	COG0688	phosphatidylethanolamine metabolic process
FOC69_RS12435	COG1183	phosphatidylcholine synthase activity
FOC69_RS12455	COG0792	nuclease activity
FOC69_RS12480	COG0534	Mate efflux family protein
FOC69_RS12485	COG0528	UMP kinase activity
FOC69_RS12495	COG0443	Heat shock 70 kDa protein
FOC69_RS12515	COG0233	cytoplasmic translational termination
FOC69_RS12520	COG1162	GTPase activity
FOC69_RS12530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS12535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC69_RS12545	COG0531	amino acid
FOC69_RS12560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC69_RS12560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC69_RS12580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC69_RS12585	COG0702	epimerase
FOC69_RS12590	COG4771	TonB-dependent receptor
FOC69_RS12600	COG1629	transport
FOC69_RS12610	COG1629	transport
FOC69_RS12610	COG4206	TonB-dependent receptor
FOC69_RS12615	COG4974	Belongs to the 'phage' integrase family
FOC69_RS12620	COG4206	TonB-dependent receptor
FOC69_RS12620	COG1629	transport
FOC69_RS12630	COG2095	MarC family integral membrane protein
FOC69_RS12645	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC69_RS12655	COG1435	thymidine kinase activity
FOC69_RS12660	COG0628	permease
FOC69_RS12670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOC69_RS12680	COG2076	Multidrug Resistance protein
FOC69_RS12730	COG1846	Transcriptional regulator
FOC69_RS12790	COG2226	methyltransferase
FOC69_RS12805	COG4771	TonB-dependent receptor
FOC69_RS12820	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC69_RS12825	COG3250	beta-galactosidase activity
FOC69_RS12830	COG3250	beta-galactosidase activity
FOC69_RS12840	COG0702	epimerase
FOC69_RS12845	COG4771	TonB-dependent receptor
FOC69_RS12900	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FOC69_RS12905	COG0460	homoserine dehydrogenase
FOC69_RS12905	COG0527	aspartate kinase activity
FOC69_RS12915	COG0489	protein tyrosine kinase activity
FOC69_RS12915	COG3206	protein involved in exopolysaccharide biosynthesis
FOC69_RS12925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC69_RS12935	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FOC69_RS12945	COG4771	TonB-dependent receptor
FOC69_RS12955	COG0826	peptidase U32
FOC69_RS12970	COG0436	Aminotransferase
FOC69_RS12975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC69_RS12975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC69_RS13030	COG2197	response regulator
FOC69_RS13080	COG0776	regulation of translation
FOC69_RS13355	COG5002	protein histidine kinase activity
FOC69_RS13360	COG2205	protein histidine kinase activity
FOC69_RS13380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOC69_RS13390	COG2204	response regulator
FOC69_RS13400	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC69_RS13425	COG3119	arylsulfatase activity
FOC69_RS13435	COG1629	transport
FOC69_RS13435	COG4206	TonB-dependent receptor
FOC69_RS13440	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC69_RS13445	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC69_RS13450	COG0737	Belongs to the 5'-nucleotidase family
FOC69_RS13455	COG0737	Belongs to the 5'-nucleotidase family
FOC69_RS13460	COG0335	large ribosomal subunit rRNA binding
FOC69_RS13465	COG1940	carbohydrate kinase activity
FOC69_RS13470	COG1136	(ABC) transporter
FOC69_RS13475	COG1136	(ABC) transporter
FOC69_RS13475	COG0577	efflux transmembrane transporter activity
FOC69_RS13480	COG1136	(ABC) transporter
FOC69_RS13480	COG0577	efflux transmembrane transporter activity
FOC69_RS13485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS13510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC69_RS13535	COG2996	Protein conserved in bacteria
FOC69_RS13540	COG0039	L-malate dehydrogenase activity
FOC69_RS13550	COG0531	amino acid
FOC69_RS13555	COG2205	protein histidine kinase activity
FOC69_RS13555	COG3437	response regulator, receiver
FOC69_RS13555	COG3850	Histidine kinase
FOC69_RS13555	COG4999	Histidine kinase
FOC69_RS13580	COG0137	argininosuccinate synthase activity
FOC69_RS13585	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC69_RS13590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC69_RS13595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FOC69_RS13600	COG1917	Cupin 2, conserved barrel domain protein
FOC69_RS13600	COG1396	sequence-specific DNA binding
FOC69_RS13605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC69_RS13615	COG1929	Belongs to the glycerate kinase type-1 family
FOC69_RS13710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC69_RS13715	COG2137	regulation of response to DNA damage stimulus
FOC69_RS13720	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC69_RS13725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC69_RS13725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC69_RS13735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC69_RS13755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC69_RS13765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC69_RS13770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC69_RS13790	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOC69_RS13810	COG0564	pseudouridine synthase activity
FOC69_RS13815	COG2815	serine threonine protein kinase
FOC69_RS13815	COG0515	serine threonine protein kinase
FOC69_RS13820	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC69_RS13825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC69_RS13830	COG0463	Glycosyl transferase, family 2
FOC69_RS13830	COG1216	Glycosyl transferase, family 2
FOC69_RS13835	COG2003	Belongs to the UPF0758 family
FOC69_RS13840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC69_RS13850	COG1785	Belongs to the alkaline phosphatase family
FOC69_RS13855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC69_RS13860	COG0280	phosphate acetyltransferase
FOC69_RS13885	COG1346	cytolysis
FOC69_RS13980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC69_RS13985	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC69_RS13990	COG2205	protein histidine kinase activity
FOC69_RS13990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS13995	COG2066	Belongs to the glutaminase family
FOC69_RS14000	COG0076	glutamate decarboxylase activity
FOC69_RS14010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC69_RS14020	COG0733	neurotransmitter:sodium symporter activity
FOC69_RS14035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC69_RS14040	COG0589	response to stress
FOC69_RS14040	COG0475	glutathione-regulated potassium exporter activity
FOC69_RS14045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC69_RS14055	COG4206	TonB-dependent receptor
FOC69_RS14055	COG1629	transport
FOC69_RS14065	COG3876	Protein conserved in bacteria
FOC69_RS14070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC69_RS14085	COG0463	Glycosyl transferase, family 2
FOC69_RS14085	COG1216	Glycosyl transferase, family 2
FOC69_RS14105	COG3876	Protein conserved in bacteria
FOC69_RS14125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC69_RS14145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC69_RS14155	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOC69_RS14160	COG3005	denitrification pathway
FOC69_RS14170	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC69_RS14175	COG0423	glycine-tRNA ligase activity
FOC69_RS14200	COG4771	TonB-dependent receptor
FOC69_RS14225	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FOC69_RS14235	COG4771	TonB-dependent receptor
FOC69_RS14260	COG3292	Two component regulator propeller
FOC69_RS14260	COG0745	RESPONSE REGULATOR receiver
FOC69_RS14260	COG2205	protein histidine kinase activity
FOC69_RS14265	COG0745	RESPONSE REGULATOR receiver
FOC69_RS14265	COG2205	protein histidine kinase activity
FOC69_RS14265	COG3292	Two component regulator propeller
FOC69_RS14270	COG1629	transport
FOC69_RS14270	COG4206	TonB-dependent receptor
FOC69_RS14285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC69_RS14290	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC69_RS14295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS14300	COG3250	beta-galactosidase activity
FOC69_RS14320	COG2954	triphosphatase activity
FOC69_RS14335	COG1022	Amp-dependent synthetase and ligase
FOC69_RS14340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC69_RS14390	COG2017	converts alpha-aldose to the beta-anomer
FOC69_RS14400	COG3537	Alpha-1,2-mannosidase
FOC69_RS14435	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC69_RS14455	COG1629	transport
FOC69_RS14455	COG4206	TonB-dependent receptor
FOC69_RS14460	COG0383	alpha-mannosidase activity
FOC69_RS14460	COG0383	alpha-mannosidase activity
FOC69_RS14490	COG3250	beta-galactosidase activity
FOC69_RS14500	COG3940	Belongs to the glycosyl hydrolase 43 family
FOC69_RS14505	COG3292	Two component regulator propeller
FOC69_RS14505	COG2205	protein histidine kinase activity
FOC69_RS14505	COG0745	RESPONSE REGULATOR receiver
FOC69_RS14510	COG4942	peptidase
FOC69_RS14525	COG0756	dUTP diphosphatase activity
FOC69_RS14550	COG4771	TonB-dependent receptor
FOC69_RS14565	COG2001	Belongs to the MraZ family
FOC69_RS14570	COG0275	rRNA processing
FOC69_RS14585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC69_RS14590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS14595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOC69_RS14600	COG0772	Belongs to the SEDS family
FOC69_RS14605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC69_RS14610	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC69_RS14625	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC69_RS14630	COG1610	YqeY-like protein
FOC69_RS14635	COG1381	Involved in DNA repair and RecF pathway recombination
FOC69_RS14645	COG0268	Binds directly to 16S ribosomal RNA
FOC69_RS14650	COG0187	DNA topoisomerase II activity
FOC69_RS14675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC69_RS14680	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOC69_RS14705	COG4771	TonB-dependent receptor
FOC69_RS14715	COG3345	alpha-galactosidase
FOC69_RS14720	COG0393	Putative heavy-metal-binding
FOC69_RS14725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC69_RS14730	COG0719	Fe-S assembly protein
FOC69_RS14735	COG0396	ATPase activity
FOC69_RS14745	COG0719	Fe-S assembly protein
FOC69_RS14755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOC69_RS14760	COG0195	Participates in both transcription termination and antitermination
FOC69_RS14765	COG0779	Required for maturation of 30S ribosomal subunits
FOC69_RS14785	COG0738	Major facilitator superfamily
FOC69_RS14790	COG1070	Carbohydrate kinase
FOC69_RS14800	COG1454	alcohol dehydrogenase
FOC69_RS14845	COG1595	DNA-templated transcription, initiation
FOC69_RS14850	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC69_RS14855	COG1166	arginine decarboxylase activity
FOC69_RS14865	COG0326	Molecular chaperone. Has ATPase activity
FOC69_RS14875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC69_RS14885	COG0328	RNA-DNA hybrid ribonuclease activity
FOC69_RS14885	COG3341	Caulimovirus viroplasmin
FOC69_RS14890	COG1132	(ABC) transporter
FOC69_RS14895	COG1216	Glycosyl transferase, family 2
FOC69_RS14895	COG1442	glycosyl transferase family 8
FOC69_RS14905	COG1442	glycosyl transferase family 8
FOC69_RS14905	COG1216	Glycosyl transferase, family 2
FOC69_RS14910	COG1442	glycosyl transferase family 8
FOC69_RS15025	COG4383	Mu-like prophage protein gp29
FOC69_RS15130	COG1216	Glycosyl transferase, family 2
FOC69_RS15140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC69_RS15145	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC69_RS15150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC69_RS15155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC69_RS15165	COG0205	6-phosphofructokinase activity
FOC69_RS15225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOC69_RS15260	COG0561	phosphatase activity
FOC69_RS15265	COG0215	cysteine-tRNA ligase activity
FOC69_RS15285	COG3250	beta-galactosidase activity
FOC69_RS15305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC69_RS15335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOC69_RS15345	COG0681	Belongs to the peptidase S26 family
FOC69_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS15360	COG1312	Catalyzes the dehydration of D-mannonate
FOC69_RS15380	COG0612	Peptidase, M16
FOC69_RS15395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC69_RS15405	COG0513	Belongs to the DEAD box helicase family
FOC69_RS15415	COG3591	Belongs to the peptidase S1B family
FOC69_RS15430	COG2255	four-way junction helicase activity
FOC69_RS15440	COG2715	membrane protein required for spore maturation
FOC69_RS15445	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC69_RS15475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC69_RS15480	COG0322	excinuclease ABC activity
FOC69_RS15490	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC69_RS15495	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC69_RS15510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC69_RS15510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC69_RS15520	COG3279	Response regulator of the LytR AlgR family
FOC69_RS15525	COG3275	phosphorelay sensor kinase activity
FOC69_RS15530	COG1045	serine acetyltransferase
FOC69_RS15535	COG0116	Belongs to the methyltransferase superfamily
FOC69_RS15535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC69_RS15540	COG0823	Involved in the tonB-independent uptake of proteins
FOC69_RS15540	COG1506	peptidase
FOC69_RS15560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOC69_RS15560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOC69_RS15570	COG1121	(ABC) transporter
FOC69_RS15605	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC69_RS15610	COG4677	pectinesterase activity
FOC69_RS15615	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS15620	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOC69_RS15625	COG3119	arylsulfatase activity
FOC69_RS15635	COG1506	peptidase
FOC69_RS15635	COG0823	Involved in the tonB-independent uptake of proteins
FOC69_RS15635	COG4946	Tricorn protease homolog
FOC69_RS15650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOC69_RS15655	COG0594	ribonuclease P activity
FOC69_RS15670	COG1611	Belongs to the LOG family
FOC69_RS15675	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC69_RS15685	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC69_RS15690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC69_RS15695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC69_RS15700	COG1968	undecaprenyl-diphosphatase activity
FOC69_RS15710	COG2177	Part of the ABC transporter FtsEX involved in
FOC69_RS15715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC69_RS15855	COG3250	beta-galactosidase activity
FOC69_RS15865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC69_RS15875	COG0427	acetyl-CoA hydrolase
FOC69_RS15895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOC69_RS15900	COG1592	Rubrerythrin
FOC69_RS15905	COG0659	secondary active sulfate transmembrane transporter activity
FOC69_RS15930	COG0731	radical SAM domain protein
FOC69_RS15930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC69_RS15950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC69_RS15965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC69_RS15970	COG0495	leucyl-tRNA aminoacylation
FOC69_RS15980	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC69_RS15990	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOC69_RS15995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC69_RS16000	COG0012	GTP binding
FOC69_RS16015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC69_RS16035	COG1595	DNA-templated transcription, initiation
FOC69_RS16055	COG0557	exoribonuclease II activity
FOC69_RS16060	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FOC69_RS16075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC69_RS16085	COG0826	peptidase U32
FOC69_RS16095	COG0758	DNA mediated transformation
FOC69_RS16095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC69_RS16120	COG4771	TonB-dependent receptor
FOC69_RS16135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC69_RS16140	COG1053	succinate dehydrogenase
FOC69_RS16170	COG0793	Belongs to the peptidase S41A family
FOC69_RS16170	COG3409	Peptidoglycan-binding domain 1 protein
FOC69_RS16175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC69_RS16210	COG1621	beta-fructofuranosidase activity
FOC69_RS16215	COG2205	protein histidine kinase activity
FOC69_RS16215	COG3292	Two component regulator propeller
FOC69_RS16215	COG0745	RESPONSE REGULATOR receiver
FOC69_RS16265	COG2814	Major facilitator Superfamily
FOC69_RS16275	COG4206	TonB-dependent receptor
FOC69_RS16275	COG1629	transport
FOC69_RS16335	COG1566	PFAM secretion protein HlyD family protein
FOC69_RS16350	COG3275	phosphorelay sensor kinase activity
FOC69_RS16370	COG1522	sequence-specific DNA binding
FOC69_RS16375	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC69_RS16380	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC69_RS16385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC69_RS16395	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS16400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC69_RS16425	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS16540	COG0606	chelatase, subunit chli
FOC69_RS16555	COG4974	Belongs to the 'phage' integrase family
FOC69_RS16560	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOC69_RS16575	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC69_RS16580	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC69_RS16595	COG4206	TonB-dependent receptor
FOC69_RS16595	COG1629	transport
FOC69_RS16605	COG3119	arylsulfatase activity
FOC69_RS16620	COG0784	Response regulator, receiver
FOC69_RS16620	COG2205	protein histidine kinase activity
FOC69_RS16620	COG5002	protein histidine kinase activity
FOC69_RS16625	COG0318	PFAM AMP-dependent synthetase and ligase
FOC69_RS16635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOC69_RS16650	COG1629	transport
FOC69_RS16685	COG1629	transport
FOC69_RS16690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOC69_RS16695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOC69_RS16700	COG0584	glycerophosphoryl diester phosphodiesterase
FOC69_RS16705	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC69_RS16710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC69_RS16710	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC69_RS16720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC69_RS16800	COG3292	Two component regulator propeller
FOC69_RS16800	COG0745	RESPONSE REGULATOR receiver
FOC69_RS16800	COG2205	protein histidine kinase activity
FOC69_RS16820	COG4771	TonB-dependent receptor
FOC69_RS16840	COG1970	mechanosensitive ion channel activity
FOC69_RS16845	COG0776	regulation of translation
FOC69_RS16910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC69_RS16915	COG3475	LICD family
FOC69_RS16940	COG3345	alpha-galactosidase
FOC69_RS16950	COG0483	inositol monophosphate 1-phosphatase activity
FOC69_RS16975	COG2814	Major facilitator Superfamily
FOC69_RS16975	COG0477	Major facilitator Superfamily
FOC69_RS16980	COG1882	Formate acetyltransferase
FOC69_RS16985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC69_RS16990	COG0745	RESPONSE REGULATOR receiver
FOC69_RS16990	COG2205	protein histidine kinase activity
FOC69_RS16990	COG3292	Two component regulator propeller
FOC69_RS16995	COG4771	TonB-dependent receptor
FOC69_RS17030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC69_RS17035	COG0793	Belongs to the peptidase S41A family
FOC69_RS17050	COG4771	TonB-dependent receptor
FOC69_RS17055	COG0702	epimerase
FOC69_RS17080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC69_RS17085	COG0509	glycine decarboxylation via glycine cleavage system
FOC69_RS17100	COG0006	proline dipeptidase activity
FOC69_RS17125	COG2205	protein histidine kinase activity
FOC69_RS17135	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC69_RS17140	COG1773	rubredoxin
FOC69_RS17145	COG0784	Response regulator, receiver
FOC69_RS17145	COG5002	protein histidine kinase activity
FOC69_RS17150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC69_RS17155	COG1011	Hydrolase
FOC69_RS17160	COG0196	riboflavin kinase activity
FOC69_RS17165	COG1266	CAAX protease self-immunity
FOC69_RS17175	COG3655	Transcriptional regulator
FOC69_RS17180	COG2166	iron-sulfur cluster assembly
FOC69_RS17185	COG2234	aminopeptidase activity
FOC69_RS17190	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC69_RS17200	COG0280	phosphate acetyltransferase
FOC69_RS17205	COG3426	butyrate kinase activity
FOC69_RS17230	COG4771	TonB-dependent receptor
FOC69_RS17245	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC69_RS17255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC69_RS17325	COG4804	nuclease activity
FOC69_RS17330	COG4974	Belongs to the 'phage' integrase family
FOC69_RS17340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOC69_RS17370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC69_RS17375	COG2207	Transcriptional regulator
FOC69_RS17375	COG0662	Cupin 2, conserved barrel domain protein
FOC69_RS17390	COG2197	response regulator
FOC69_RS17410	COG4206	TonB-dependent receptor
FOC69_RS17425	COG3279	Response regulator of the LytR AlgR family
FOC69_RS17440	COG0657	acetylesterase activity
FOC69_RS17440	COG2755	lipolytic protein G-D-S-L family
FOC69_RS17470	COG2096	Adenosyltransferase
FOC69_RS17485	COG0252	asparaginase activity
FOC69_RS17490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC69_RS17495	COG1027	Aspartate ammonia-lyase
FOC69_RS17515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC69_RS17525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC69_RS17530	COG1480	7TM receptor with intracellular HD hydrolase
FOC69_RS17535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC69_RS17545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC69_RS17550	COG0006	proline dipeptidase activity
FOC69_RS17555	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC69_RS17560	COG4974	Belongs to the 'phage' integrase family
FOC69_RS17565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOC69_RS17610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC69_RS17615	COG0081	regulation of translation
FOC69_RS17620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC69_RS17625	COG0222	ribosome binding
FOC69_RS17630	COG0085	RNA polymerase activity
FOC69_RS17635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC69_RS17665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC69_RS17670	COG0049	tRNA binding
FOC69_RS17675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC69_RS17680	COG0051	transcription antitermination factor activity, RNA binding
FOC69_RS17685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOC69_RS17690	COG0088	Forms part of the polypeptide exit tunnel
FOC69_RS17695	COG0089	rRNA binding
FOC69_RS17700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOC69_RS17705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC69_RS17710	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOC69_RS17715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC69_RS17720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC69_RS17725	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC69_RS17730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC69_RS17735	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC69_RS17740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC69_RS17745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOC69_RS17750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC69_RS17755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC69_RS17760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC69_RS17765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC69_RS17770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC69_RS17775	COG1841	ribosomal large subunit assembly
FOC69_RS17780	COG0200	Binds to the 23S rRNA
FOC69_RS17795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC69_RS17800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC69_RS17805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC69_RS17810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC69_RS17815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC69_RS17820	COG0202	RNA polymerase activity
FOC69_RS17825	COG0203	ribosomal protein L17
FOC69_RS17855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC69_RS17865	COG1228	amidohydrolase
FOC69_RS17875	COG2986	histidine ammonia-lyase
FOC69_RS17880	COG1309	transcriptional regulator
FOC69_RS17915	COG1696	Membrane protein involved in D-alanine export
FOC69_RS18005	COG1131	(ABC) transporter
FOC69_RS18045	COG0564	pseudouridine synthase activity
FOC69_RS18060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC69_RS18065	COG0612	Peptidase, M16
FOC69_RS18070	COG0534	Mate efflux family protein
FOC69_RS18075	COG2205	protein histidine kinase activity
FOC69_RS18075	COG0784	Response regulator, receiver
FOC69_RS18120	COG0297	glycogen (starch) synthase activity
FOC69_RS18135	COG1216	Glycosyl transferase, family 2
FOC69_RS18145	COG0488	(ABC) transporter
FOC69_RS18150	COG3590	peptidase
FOC69_RS18155	COG0138	bifunctional purine biosynthesis protein purh
FOC69_RS18165	COG1792	Involved in formation and maintenance of cell shape
FOC69_RS18180	COG0772	Belongs to the SEDS family
FOC69_RS18190	COG1774	PSP1 C-terminal conserved region
FOC69_RS18195	COG0470	DNA polymerase III
FOC69_RS18200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC69_RS18240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS18245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC69_RS18250	COG1160	GTP binding
FOC69_RS18255	COG0745	RESPONSE REGULATOR receiver
FOC69_RS18260	COG1127	ABC transporter
FOC69_RS18265	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC69_RS18275	COG0724	RNA recognition motif
FOC69_RS18280	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC69_RS18290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC69_RS18295	COG0514	ATP-dependent DNA helicase (RecQ)
FOC69_RS18300	COG0517	IMP dehydrogenase activity
FOC69_RS18300	COG0516	GMP reductase activity
FOC69_RS18315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC69_RS18330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC69_RS18405	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS18445	COG1216	Glycosyl transferase, family 2
FOC69_RS18445	COG1442	glycosyl transferase family 8
FOC69_RS18480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC69_RS18535	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS18540	COG3022	response to hydroperoxide
FOC69_RS18545	COG0110	maltose O-acetyltransferase activity
FOC69_RS18575	COG1187	pseudouridine synthase activity
FOC69_RS18580	COG0017	Asparaginyl-tRNA synthetase
FOC69_RS18590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC69_RS18595	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC69_RS18600	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC69_RS18605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC69_RS18615	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOC69_RS18620	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC69_RS18625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC69_RS18640	COG0482	sulfurtransferase activity
FOC69_RS18650	COG1570	exodeoxyribonuclease VII activity
FOC69_RS18660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC69_RS18675	COG0489	protein tyrosine kinase activity
FOC69_RS18680	COG3118	belongs to the thioredoxin family
FOC69_RS18700	COG4948	Mandelate Racemase Muconate Lactonizing
FOC69_RS18715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS18770	COG0039	L-malate dehydrogenase activity
FOC69_RS18775	COG1506	peptidase
FOC69_RS18775	COG0823	Involved in the tonB-independent uptake of proteins
FOC69_RS18775	COG4946	Tricorn protease homolog
FOC69_RS18805	COG1629	transport
FOC69_RS18865	COG4974	Belongs to the 'phage' integrase family
FOC69_RS18900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC69_RS18900	COG0551	DNA topoisomerase type I activity
FOC69_RS18920	COG0784	Response regulator, receiver
FOC69_RS18920	COG2198	Histidine kinase
FOC69_RS18920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS18920	COG2205	protein histidine kinase activity
FOC69_RS19040	COG0358	DNA primase activity
FOC69_RS19135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC69_RS19145	COG0811	peptide transport
FOC69_RS19170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC69_RS19175	COG0105	UTP biosynthetic process
FOC69_RS19180	COG0739	heme binding
FOC69_RS19195	COG0149	triose-phosphate isomerase activity
FOC69_RS19205	COG0302	gtp cyclohydrolase
FOC69_RS19220	COG1629	transport
FOC69_RS19220	COG4206	TonB-dependent receptor
FOC69_RS19225	COG0702	epimerase
FOC69_RS19230	COG3119	arylsulfatase activity
FOC69_RS19235	COG0358	DNA primase activity
FOC69_RS19245	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC69_RS19250	COG0436	Aminotransferase
FOC69_RS19265	COG0514	ATP-dependent DNA helicase (RecQ)
FOC69_RS19270	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC69_RS19270	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC69_RS19275	COG2818	Glycosylase
FOC69_RS19305	COG0726	polysaccharide deacetylase
FOC69_RS19320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC69_RS19350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC69_RS19360	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS19365	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS19370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS19375	COG0656	L-ascorbic acid biosynthetic process
FOC69_RS19390	COG1216	Glycosyl transferase, family 2
FOC69_RS19395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS19400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS19430	COG0009	L-threonylcarbamoyladenylate synthase
FOC69_RS19440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC69_RS19445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC69_RS19450	COG0658	competence protein
FOC69_RS19455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC69_RS19465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC69_RS19470	COG3250	beta-galactosidase activity
FOC69_RS19485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC69_RS19495	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC69_RS19505	COG3279	Response regulator of the LytR AlgR family
FOC69_RS19510	COG3275	phosphorelay sensor kinase activity
FOC69_RS19530	COG0386	Belongs to the glutathione peroxidase family
FOC69_RS19535	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOC69_RS19540	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC69_RS19555	COG2431	L-lysine efflux transmembrane transporter activity
FOC69_RS19570	COG4771	TonB-dependent receptor
FOC69_RS19590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC69_RS19610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC69_RS19635	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC69_RS19640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC69_RS19645	COG0359	binds to the 23S rRNA
FOC69_RS19655	COG1022	Amp-dependent synthetase and ligase
FOC69_RS19660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC69_RS19680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC69_RS19685	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOC69_RS19695	COG1640	4-alpha-glucanotransferase
FOC69_RS19710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC69_RS19720	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC69_RS19745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS19760	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC69_RS19765	COG2502	aspartate--ammonia ligase
FOC69_RS19775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC69_RS19785	COG0166	Belongs to the GPI family
FOC69_RS19790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC69_RS19795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOC69_RS19805	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC69_RS19815	COG3850	Histidine kinase
FOC69_RS19815	COG3437	response regulator, receiver
FOC69_RS19815	COG2205	protein histidine kinase activity
FOC69_RS19815	COG4999	Histidine kinase
FOC69_RS19825	COG0534	Mate efflux family protein
FOC69_RS19840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC69_RS19845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC69_RS19845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC69_RS19865	COG1012	belongs to the aldehyde dehydrogenase family
FOC69_RS19875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC69_RS19895	COG4771	TonB-dependent receptor
FOC69_RS19910	COG4771	TonB-dependent receptor
FOC69_RS19915	COG0702	epimerase
FOC69_RS19930	COG4771	TonB-dependent receptor
FOC69_RS19935	COG0702	epimerase
FOC69_RS19945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FOC69_RS19955	COG3119	arylsulfatase activity
FOC69_RS19990	COG3681	Belongs to the UPF0597 family
FOC69_RS20010	COG2885	chlorophyll binding
FOC69_RS20030	COG0129	dihydroxy-acid dehydratase activity
FOC69_RS20055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC69_RS20065	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC69_RS20075	COG0538	isocitrate dehydrogenase activity
FOC69_RS20080	COG0372	Belongs to the citrate synthase family
FOC69_RS20090	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC69_RS20090	COG1902	pentaerythritol trinitrate reductase activity
FOC69_RS20100	COG0205	6-phosphofructokinase activity
FOC69_RS20105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC69_RS20110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOC69_RS20115	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FOC69_RS20130	COG0084	hydrolase, TatD family'
FOC69_RS20140	COG0811	peptide transport
FOC69_RS20165	COG1522	sequence-specific DNA binding
FOC69_RS20175	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOC69_RS20185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC69_RS20210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOC69_RS20210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FOC69_RS20245	COG0488	(ABC) transporter
FOC69_RS20250	COG2204	response regulator
FOC69_RS20260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC69_RS20270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC69_RS20275	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC69_RS20280	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC69_RS20285	COG1408	metallophosphoesterase
FOC69_RS20290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC69_RS20295	COG0194	GDP metabolic process
FOC69_RS20310	COG2198	Histidine kinase
FOC69_RS20310	COG2205	protein histidine kinase activity
FOC69_RS20310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC69_RS20310	COG0784	Response regulator, receiver
FOC69_RS20315	COG1214	PFAM Peptidase M22, glycoprotease
FOC69_RS20325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC69_RS20330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOC69_RS20340	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC69_RS20345	COG0750	zinc metalloprotease
FOC69_RS20355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC69_RS20365	COG2814	Major facilitator Superfamily
FOC69_RS20375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC69_RS20375	COG1328	CTP reductase activity
FOC69_RS20380	COG1272	protein, Hemolysin III
FOC69_RS20385	COG0673	inositol 2-dehydrogenase activity
FOC69_RS20390	COG0632	four-way junction helicase activity
FOC69_RS20410	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC69_RS20420	COG0776	regulation of translation
FOC69_RS20465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC69_RS20475	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC69_RS20490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC69_RS20505	COG0438	transferase activity, transferring glycosyl groups
FOC69_RS20555	COG1278	Cold shock
FOC69_RS20565	COG0612	Peptidase, M16
FOC69_RS20590	COG0517	IMP dehydrogenase activity
FOC69_RS20590	COG0617	tRNA 3'-terminal CCA addition
FOC69_RS20590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC69_RS20615	COG1505	serine-type exopeptidase activity
FOC69_RS20665	COG2378	regulation of single-species biofilm formation
FOC69_RS20670	COG3340	Belongs to the peptidase S51 family
FOC69_RS20705	COG4771	TonB-dependent receptor
FOC69_RS20720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC69_RS20745	COG1418	mRNA catabolic process
FOC69_RS20750	COG3142	Participates in the control of copper homeostasis
FOC69_RS20765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC69_RS20770	COG2832	Protein of unknown function (DUF454)
FOC69_RS20780	COG0602	queuosine metabolic process
FOC69_RS20785	COG0247	lactate metabolic process
FOC69_RS20790	COG1139	Iron-sulfur cluster binding protein
FOC69_RS20800	COG0351	phosphomethylpyrimidine kinase
FOC69_RS20810	COG2304	oxidoreductase activity
FOC69_RS20820	COG1629	transport
FOC69_RS20830	COG1393	Belongs to the ArsC family
FOC69_RS20845	COG2233	PERMEase
FOC69_RS20850	COG1509	lysine 2,3-aminomutase activity
FOC69_RS20860	COG1115	amino acid carrier protein
FOC69_RS20875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC69_RS20875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC69_RS20895	COG1285	pathogenesis
FOC69_RS20905	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC69_RS20905	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC69_RS20910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC69_RS20915	COG1388	LysM domain
FOC69_RS20915	COG0741	lytic transglycosylase activity
FOC69_RS20925	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC69_RS20965	COG2076	Multidrug Resistance protein
FOC69_RS20980	COG0110	maltose O-acetyltransferase activity
FOC69_RS21020	COG2873	o-acetylhomoserine
FOC69_RS21055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS21070	COG0517	IMP dehydrogenase activity
FOC69_RS21070	COG0516	GMP reductase activity
FOC69_RS21075	COG2207	Transcriptional regulator
FOC69_RS21080	COG0784	Response regulator, receiver
FOC69_RS21080	COG5002	protein histidine kinase activity
FOC69_RS21080	COG2205	protein histidine kinase activity
FOC69_RS21090	COG1335	isochorismatase
FOC69_RS21100	COG1917	Cupin 2, conserved barrel domain protein
FOC69_RS21100	COG4977	sequence-specific DNA binding
FOC69_RS21105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC69_RS21110	COG0511	ligase activity, forming carbon-carbon bonds
FOC69_RS21115	COG0439	Biotin carboxylase
FOC69_RS21120	COG4651	solute:proton antiporter activity
FOC69_RS21120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC69_RS21125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC69_RS21130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC69_RS21145	COG1028	Short-chain dehydrogenase reductase Sdr
FOC69_RS21160	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOC69_RS21175	COG4974	Belongs to the 'phage' integrase family
FOC69_RS21195	COG5290	Psort location Cytoplasmic, score
FOC69_RS21350	COG4974	Belongs to the 'phage' integrase family
FOC69_RS21360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC69_RS21370	COG2910	NAD(P)H-binding
FOC69_RS21375	COG2176	DNA-directed DNA polymerase activity
FOC69_RS21385	COG4864	UPF0365 protein
FOC69_RS21400	COG0037	tRNA processing
FOC69_RS21410	COG1477	protein flavinylation
FOC69_RS21415	COG1971	Probably functions as a manganese efflux pump
FOC69_RS21430	COG0463	Glycosyl transferase, family 2
FOC69_RS21450	COG2207	Transcriptional regulator
FOC69_RS21450	COG1917	Cupin 2, conserved barrel domain protein
FOC69_RS21545	COG1132	(ABC) transporter
FOC69_RS21580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOC69_RS21585	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC69_RS21595	COG0616	signal peptide processing
FOC69_RS21640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC69_RS21645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC69_RS21650	COG0066	3-isopropylmalate dehydratase activity
FOC69_RS21655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC69_RS21665	COG0463	Glycosyl transferase, family 2
FOC69_RS21690	COG1629	transport
FOC69_RS21690	COG4206	TonB-dependent receptor
FOC69_RS21695	COG0702	epimerase
FOC69_RS21710	COG0671	phosphoesterase, PA-phosphatase related
FOC69_RS21720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC69_RS21730	COG0514	ATP-dependent DNA helicase (RecQ)
FOC69_RS21760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC69_RS21790	COG0823	Involved in the tonB-independent uptake of proteins
FOC69_RS21790	COG1506	peptidase
FOC69_RS21795	COG3537	Alpha-1,2-mannosidase
FOC69_RS21840	COG2326	polyphosphate kinase activity
FOC69_RS21880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC69_RS21885	COG0459	protein refolding
FOC69_RS21900	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOC69_RS21905	COG0028	Belongs to the TPP enzyme family
FOC69_RS21950	COG2194	sulfuric ester hydrolase activity
FOC69_RS21960	COG0484	heat shock protein binding
FOC69_RS21980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC69_RS22000	COG0702	epimerase
FOC69_RS22005	COG1629	transport
FOC69_RS22005	COG4206	TonB-dependent receptor
FOC69_RS22010	COG4948	Mandelate Racemase Muconate Lactonizing
FOC69_RS22025	COG3279	Response regulator of the LytR AlgR family
FOC69_RS22035	COG3015	lipoprotein NlpE involved in copper resistance
FOC69_RS22060	COG0475	glutathione-regulated potassium exporter activity
FOC69_RS22065	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC69_RS22080	COG0738	Major facilitator superfamily
FOC69_RS22120	COG1621	beta-fructofuranosidase activity
FOC69_RS22130	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOC69_RS22130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOC69_RS22135	COG0745	RESPONSE REGULATOR receiver
FOC69_RS22135	COG2205	protein histidine kinase activity
FOC69_RS22135	COG3292	Two component regulator propeller
FOC69_RS22150	COG4176	ABC-type proline glycine betaine transport system permease component
FOC69_RS22155	COG2113	Glycine betaine
FOC69_RS22190	COG1649	PFAM Uncharacterised BCR, COG1649
FOC69_RS22195	COG1966	Carbon starvation protein
FOC69_RS22215	COG1649	PFAM Uncharacterised BCR, COG1649
FOC69_RS22230	COG0745	RESPONSE REGULATOR receiver
FOC69_RS22230	COG2205	protein histidine kinase activity
FOC69_RS22230	COG3292	Two component regulator propeller
FOC69_RS22260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC69_RS22265	COG1554	hydrolase, family 65, central catalytic
FOC69_RS22315	COG1609	Transcriptional regulator
FOC69_RS22320	COG1629	transport
FOC69_RS22320	COG4206	TonB-dependent receptor
FOC69_RS22325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC69_RS22350	COG0254	rRNA binding
FOC69_RS22360	COG0191	fructose-bisphosphate aldolase activity
FOC69_RS22380	COG0366	Alpha amylase catalytic
FOC69_RS22395	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOC69_RS22400	COG0511	ligase activity, forming carbon-carbon bonds
FOC69_RS22400	COG5016	pyruvate
FOC69_RS22410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC69_RS22425	COG0288	reversible hydration of carbon dioxide
FOC69_RS22430	COG0778	Nitroreductase
FOC69_RS22445	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOC69_RS22450	COG0424	maF-like protein
FOC69_RS22500	COG2311	Membrane
FOC69_RS22515	COG0126	phosphoglycerate kinase activity
FOC69_RS22530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOC69_RS22550	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOC69_RS22555	COG1523	belongs to the glycosyl hydrolase 13 family
FOC69_RS22570	COG1629	transport
FOC69_RS22570	COG4206	TonB-dependent receptor
FOC69_RS22580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS22585	COG3119	arylsulfatase activity
FOC69_RS22590	COG1119	ATPase activity
FOC69_RS22600	COG0588	phosphoglycerate mutase activity
FOC69_RS22605	COG1830	Aldolase
FOC69_RS22610	COG0745	RESPONSE REGULATOR receiver
FOC69_RS22610	COG3292	Two component regulator propeller
FOC69_RS22610	COG2205	protein histidine kinase activity
FOC69_RS22615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS22620	COG3119	arylsulfatase activity
FOC69_RS22625	COG3119	arylsulfatase activity
FOC69_RS22630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC69_RS22635	COG3250	beta-galactosidase activity
FOC69_RS22645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC69_RS22650	COG0668	transmembrane transport
FOC69_RS22660	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC69_RS22700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC69_RS22845	COG3392	D12 class N6 adenine-specific DNA methyltransferase
FOC69_RS23010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC69_RS23015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC69_RS23020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC69_RS23025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC69_RS23030	COG0534	Mate efflux family protein
FOC69_RS23035	COG2202	Pas domain
FOC69_RS23035	COG2205	protein histidine kinase activity
FOC69_RS23090	COG1216	Glycosyl transferase, family 2
FOC69_RS23095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOC69_RS23110	COG5492	domain, Protein
FOC69_RS23115	COG1215	transferase activity, transferring glycosyl groups
FOC69_RS23120	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC69_RS23130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC69_RS23135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOC69_RS23145	COG1295	ribonuclease BN
FOC69_RS23155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC69_RS23190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC69_RS23195	COG1410	methionine synthase
FOC69_RS23195	COG0646	methionine synthase
FOC69_RS23205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC69_RS23210	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC69_RS23215	COG0572	uridine kinase
FOC69_RS23225	COG4232	protein-disulfide reductase activity
FOC69_RS23230	COG1741	Belongs to the pirin family
FOC69_RS23240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC69_RS23245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC69_RS23255	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOC69_RS23255	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC69_RS23270	COG4206	TonB-dependent receptor
FOC69_RS23270	COG1629	transport
FOC69_RS23280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC69_RS23280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC69_RS23285	COG0339	signal peptide processing
FOC69_RS23290	COG3152	Membrane
FOC69_RS23300	COG1773	rubredoxin
FOC69_RS23300	COG1592	Rubrerythrin
FOC69_RS23335	COG3591	Belongs to the peptidase S1B family
FOC69_RS23340	COG3591	Belongs to the peptidase S1B family
FOC69_RS23345	COG0641	radical SAM
FOC69_RS23450	COG0681	Belongs to the peptidase S26 family
FOC69_RS23485	COG0420	3'-5' exonuclease activity
FOC69_RS23500	COG1132	(ABC) transporter
FOC69_RS23505	COG1132	(ABC) transporter
FOC69_RS23510	COG1408	metallophosphoesterase
FOC69_RS23550	COG1410	methionine synthase
FOC69_RS23550	COG0646	methionine synthase
FOC69_RS23555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOC69_RS23560	COG0463	Glycosyl transferase, family 2
FOC69_RS23565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC69_RS23570	COG1032	radical SAM domain protein
FOC69_RS23610	COG0363	glucosamine-6-phosphate deaminase activity
FOC69_RS23670	COG1629	transport
FOC69_RS23670	COG4206	TonB-dependent receptor
FOC69_RS23675	COG0561	phosphatase activity
FOC69_RS23770	COG3326	Membrane
FOC69_RS23780	COG0494	nUDIX hydrolase
FOC69_RS23795	COG0693	protein deglycase activity
FOC69_RS23805	COG4977	sequence-specific DNA binding
FOC69_RS23805	COG1917	Cupin 2, conserved barrel domain protein
FOC69_RS23830	COG3586	endonuclease activity