locus-tag	class	description
BF9343_RS00020	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS00070	COG0731	radical SAM domain protein
BF9343_RS00070	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF9343_RS00095	COG0659	secondary active sulfate transmembrane transporter activity
BF9343_RS00100	COG1592	Rubrerythrin
BF9343_RS00105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF9343_RS00125	COG0427	acetyl-CoA hydrolase
BF9343_RS00135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF9343_RS00145	COG3250	beta-galactosidase activity
BF9343_RS00285	COG2177	Part of the ABC transporter FtsEX involved in
BF9343_RS00295	COG1968	undecaprenyl-diphosphatase activity
BF9343_RS00300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BF9343_RS00305	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BF9343_RS00310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BF9343_RS00315	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BF9343_RS00320	COG1611	Belongs to the LOG family
BF9343_RS00335	COG0594	ribonuclease P activity
BF9343_RS00345	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BF9343_RS00350	COG4946	Tricorn protease homolog
BF9343_RS00350	COG1506	peptidase
BF9343_RS00350	COG0823	Involved in the tonB-independent uptake of proteins
BF9343_RS00360	COG3119	arylsulfatase activity
BF9343_RS00365	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BF9343_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS00380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BF9343_RS00410	COG1121	(ABC) transporter
BF9343_RS00420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BF9343_RS00420	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BF9343_RS00435	COG0151	Belongs to the GarS family
BF9343_RS00440	COG1506	peptidase
BF9343_RS00440	COG0823	Involved in the tonB-independent uptake of proteins
BF9343_RS00445	COG0116	Belongs to the methyltransferase superfamily
BF9343_RS00450	COG1045	serine acetyltransferase
BF9343_RS00455	COG3275	phosphorelay sensor kinase activity
BF9343_RS00460	COG3279	Response regulator of the LytR AlgR family
BF9343_RS00470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF9343_RS00470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BF9343_RS00485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BF9343_RS00490	COG1694	Mazg nucleotide pyrophosphohydrolase
BF9343_RS00495	COG1490	D-aminoacyl-tRNA deacylase activity
BF9343_RS00500	COG0322	excinuclease ABC activity
BF9343_RS00505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF9343_RS00510	COG0445	tRNA wobble uridine modification
BF9343_RS00535	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BF9343_RS00555	COG2715	membrane protein required for spore maturation
BF9343_RS00565	COG2255	four-way junction helicase activity
BF9343_RS00580	COG3591	Belongs to the peptidase S1B family
BF9343_RS00595	COG0513	Belongs to the DEAD box helicase family
BF9343_RS00605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF9343_RS00620	COG0612	Peptidase, M16
BF9343_RS00635	COG1312	Catalyzes the dehydration of D-mannonate
BF9343_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS00650	COG0681	Belongs to the peptidase S26 family
BF9343_RS00655	COG0681	Belongs to the peptidase S26 family
BF9343_RS00660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BF9343_RS00690	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BF9343_RS00705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS00710	COG3250	beta-galactosidase activity
BF9343_RS00730	COG0215	cysteine-tRNA ligase activity
BF9343_RS00735	COG0561	phosphatase activity
BF9343_RS00740	COG0745	RESPONSE REGULATOR receiver
BF9343_RS00755	COG0745	RESPONSE REGULATOR receiver
BF9343_RS00760	COG5002	protein histidine kinase activity
BF9343_RS00765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF9343_RS00780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BF9343_RS00785	COG0482	sulfurtransferase activity
BF9343_RS00795	COG0205	6-phosphofructokinase activity
BF9343_RS00800	COG0571	ribonuclease III activity
BF9343_RS00805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BF9343_RS00810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BF9343_RS00815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BF9343_RS00820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF9343_RS00835	COG1442	glycosyl transferase family 8
BF9343_RS00845	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS00850	COG1216	Glycosyl transferase, family 2
BF9343_RS00850	COG1442	glycosyl transferase family 8
BF9343_RS00855	COG1132	(ABC) transporter
BF9343_RS00865	COG3341	Caulimovirus viroplasmin
BF9343_RS00865	COG0328	RNA-DNA hybrid ribonuclease activity
BF9343_RS00880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BF9343_RS00890	COG0326	Molecular chaperone. Has ATPase activity
BF9343_RS00900	COG1166	arginine decarboxylase activity
BF9343_RS00905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BF9343_RS00975	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BF9343_RS00980	COG1454	alcohol dehydrogenase
BF9343_RS00985	COG0235	Class ii aldolase
BF9343_RS00990	COG1070	Carbohydrate kinase
BF9343_RS00995	COG0738	Major facilitator superfamily
BF9343_RS01000	COG0779	Required for maturation of 30S ribosomal subunits
BF9343_RS01005	COG0195	Participates in both transcription termination and antitermination
BF9343_RS01010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BF9343_RS01020	COG0719	Fe-S assembly protein
BF9343_RS01030	COG0396	ATPase activity
BF9343_RS01035	COG0719	Fe-S assembly protein
BF9343_RS01040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BF9343_RS01045	COG0393	Putative heavy-metal-binding
BF9343_RS01050	COG3345	alpha-galactosidase
BF9343_RS01060	COG1629	transport
BF9343_RS01085	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BF9343_RS01095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BF9343_RS01105	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BF9343_RS01110	COG2202	Pas domain
BF9343_RS01110	COG2205	protein histidine kinase activity
BF9343_RS01130	COG0187	DNA topoisomerase II activity
BF9343_RS01135	COG0268	Binds directly to 16S ribosomal RNA
BF9343_RS01145	COG1381	Involved in DNA repair and RecF pathway recombination
BF9343_RS01150	COG1610	YqeY-like protein
BF9343_RS01155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BF9343_RS01170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BF9343_RS01175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BF9343_RS01180	COG0772	Belongs to the SEDS family
BF9343_RS01185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BF9343_RS01190	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS01195	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BF9343_RS01210	COG0275	rRNA processing
BF9343_RS01215	COG2001	Belongs to the MraZ family
BF9343_RS01235	COG4771	TonB-dependent receptor
BF9343_RS01260	COG0756	dUTP diphosphatase activity
BF9343_RS01275	COG4942	peptidase
BF9343_RS01280	COG3292	Two component regulator propeller
BF9343_RS01280	COG2205	protein histidine kinase activity
BF9343_RS01280	COG0745	RESPONSE REGULATOR receiver
BF9343_RS01285	COG3940	Belongs to the glycosyl hydrolase 43 family
BF9343_RS01300	COG3250	beta-galactosidase activity
BF9343_RS01315	COG3940	Belongs to the glycosyl hydrolase 43 family
BF9343_RS01335	COG0383	alpha-mannosidase activity
BF9343_RS01340	COG1629	transport
BF9343_RS01340	COG4206	TonB-dependent receptor
BF9343_RS01360	COG3507	Belongs to the glycosyl hydrolase 43 family
BF9343_RS01385	COG3537	Alpha-1,2-mannosidase
BF9343_RS01395	COG2017	converts alpha-aldose to the beta-anomer
BF9343_RS01470	COG3408	Glycogen debranching enzyme
BF9343_RS01475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BF9343_RS01480	COG1022	Amp-dependent synthetase and ligase
BF9343_RS01500	COG2954	triphosphatase activity
BF9343_RS01520	COG3250	beta-galactosidase activity
BF9343_RS01525	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS01535	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BF9343_RS01550	COG4206	TonB-dependent receptor
BF9343_RS01550	COG1629	transport
BF9343_RS01555	COG3292	Two component regulator propeller
BF9343_RS01555	COG0745	RESPONSE REGULATOR receiver
BF9343_RS01555	COG2205	protein histidine kinase activity
BF9343_RS01560	COG0745	RESPONSE REGULATOR receiver
BF9343_RS01560	COG2205	protein histidine kinase activity
BF9343_RS01560	COG3292	Two component regulator propeller
BF9343_RS01585	COG4771	TonB-dependent receptor
BF9343_RS01600	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BF9343_RS01620	COG4771	TonB-dependent receptor
BF9343_RS01645	COG0423	glycine-tRNA ligase activity
BF9343_RS01650	COG0545	Peptidyl-prolyl cis-trans isomerase
BF9343_RS01680	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BF9343_RS01690	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF9343_RS01710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BF9343_RS01730	COG3876	Protein conserved in bacteria
BF9343_RS01765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF9343_RS01770	COG3876	Protein conserved in bacteria
BF9343_RS01775	COG0702	epimerase
BF9343_RS01780	COG4206	TonB-dependent receptor
BF9343_RS01780	COG1629	transport
BF9343_RS01795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BF9343_RS01800	COG0475	glutathione-regulated potassium exporter activity
BF9343_RS01800	COG0589	response to stress
BF9343_RS01805	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BF9343_RS01810	COG1136	(ABC) transporter
BF9343_RS01820	COG0733	neurotransmitter:sodium symporter activity
BF9343_RS01830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BF9343_RS01840	COG0076	glutamate decarboxylase activity
BF9343_RS01845	COG2066	Belongs to the glutaminase family
BF9343_RS01850	COG2198	Histidine kinase
BF9343_RS01850	COG0784	Response regulator, receiver
BF9343_RS01850	COG5002	protein histidine kinase activity
BF9343_RS01855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BF9343_RS01860	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BF9343_RS01945	COG1346	cytolysis
BF9343_RS01970	COG0280	phosphate acetyltransferase
BF9343_RS01975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BF9343_RS01980	COG1785	Belongs to the alkaline phosphatase family
BF9343_RS01985	COG2151	metal-sulfur cluster biosynthetic enzyme
BF9343_RS01990	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BF9343_RS01995	COG2003	Belongs to the UPF0758 family
BF9343_RS02000	COG1216	Glycosyl transferase, family 2
BF9343_RS02000	COG0463	Glycosyl transferase, family 2
BF9343_RS02015	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BF9343_RS02020	COG2815	serine threonine protein kinase
BF9343_RS02020	COG0515	serine threonine protein kinase
BF9343_RS02025	COG0564	pseudouridine synthase activity
BF9343_RS02030	COG1181	Belongs to the D-alanine--D-alanine ligase family
BF9343_RS02065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BF9343_RS02070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BF9343_RS02080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BF9343_RS02100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BF9343_RS02110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF9343_RS02110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BF9343_RS02115	COG2890	protein-(glutamine-N5) methyltransferase activity
BF9343_RS02120	COG2137	regulation of response to DNA damage stimulus
BF9343_RS02125	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BF9343_RS02135	COG0165	Argininosuccinate lyase
BF9343_RS02210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BF9343_RS02215	COG1917	Cupin 2, conserved barrel domain protein
BF9343_RS02215	COG1396	sequence-specific DNA binding
BF9343_RS02220	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BF9343_RS02225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF9343_RS02230	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BF9343_RS02235	COG0137	argininosuccinate synthase activity
BF9343_RS02245	COG1438	arginine binding
BF9343_RS02260	COG2205	protein histidine kinase activity
BF9343_RS02260	COG0784	Response regulator, receiver
BF9343_RS02265	COG0531	amino acid
BF9343_RS02275	COG0039	L-malate dehydrogenase activity
BF9343_RS02280	COG2996	Protein conserved in bacteria
BF9343_RS02300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF9343_RS02305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BF9343_RS02330	COG1629	transport
BF9343_RS02355	COG0577	efflux transmembrane transporter activity
BF9343_RS02355	COG1136	(ABC) transporter
BF9343_RS02360	COG1136	(ABC) transporter
BF9343_RS02360	COG0577	efflux transmembrane transporter activity
BF9343_RS02365	COG1136	(ABC) transporter
BF9343_RS02370	COG1940	carbohydrate kinase activity
BF9343_RS02375	COG0335	large ribosomal subunit rRNA binding
BF9343_RS02380	COG0737	Belongs to the 5'-nucleotidase family
BF9343_RS02385	COG0737	Belongs to the 5'-nucleotidase family
BF9343_RS02390	COG1472	Belongs to the glycosyl hydrolase 3 family
BF9343_RS02395	COG1472	Belongs to the glycosyl hydrolase 3 family
BF9343_RS02400	COG1629	transport
BF9343_RS02400	COG4206	TonB-dependent receptor
BF9343_RS02410	COG3119	arylsulfatase activity
BF9343_RS02435	COG0446	pyridine nucleotide-disulphide oxidoreductase
BF9343_RS02445	COG2204	response regulator
BF9343_RS02450	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BF9343_RS02460	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BF9343_RS02470	COG2205	protein histidine kinase activity
BF9343_RS02475	COG5002	protein histidine kinase activity
BF9343_RS02490	COG4771	TonB-dependent receptor
BF9343_RS02535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF9343_RS02535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BF9343_RS02540	COG0436	Aminotransferase
BF9343_RS02545	COG3250	beta-galactosidase activity
BF9343_RS02555	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BF9343_RS02560	COG0826	peptidase U32
BF9343_RS02570	COG4771	TonB-dependent receptor
BF9343_RS02575	COG2197	response regulator
BF9343_RS02580	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BF9343_RS02590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BF9343_RS02595	COG0252	asparaginase activity
BF9343_RS02600	COG0460	homoserine dehydrogenase
BF9343_RS02600	COG0527	aspartate kinase activity
BF9343_RS02605	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BF9343_RS02610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BF9343_RS02665	COG1629	transport
BF9343_RS02665	COG4206	TonB-dependent receptor
BF9343_RS02670	COG0702	epimerase
BF9343_RS02675	COG3250	beta-galactosidase activity
BF9343_RS02685	COG3507	Belongs to the glycosyl hydrolase 43 family
BF9343_RS02700	COG4771	TonB-dependent receptor
BF9343_RS02715	COG0628	permease
BF9343_RS02720	COG1435	thymidine kinase activity
BF9343_RS02730	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BF9343_RS02745	COG2095	MarC family integral membrane protein
BF9343_RS02755	COG1629	transport
BF9343_RS02765	COG1629	transport
BF9343_RS02770	COG4974	Belongs to the 'phage' integrase family
BF9343_RS02775	COG4206	TonB-dependent receptor
BF9343_RS02775	COG1629	transport
BF9343_RS02785	COG4771	TonB-dependent receptor
BF9343_RS02790	COG0702	epimerase
BF9343_RS02795	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BF9343_RS02810	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BF9343_RS02810	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BF9343_RS02825	COG0531	amino acid
BF9343_RS02835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF9343_RS02840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS02845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS02875	COG1162	GTPase activity
BF9343_RS02880	COG0233	cytoplasmic translational termination
BF9343_RS02900	COG0443	Heat shock 70 kDa protein
BF9343_RS02915	COG0528	UMP kinase activity
BF9343_RS02920	COG0534	Mate efflux family protein
BF9343_RS02950	COG0792	nuclease activity
BF9343_RS02970	COG1183	phosphatidylcholine synthase activity
BF9343_RS02975	COG0688	phosphatidylethanolamine metabolic process
BF9343_RS02985	COG3118	belongs to the thioredoxin family
BF9343_RS03020	COG0714	Associated with various cellular activities
BF9343_RS03035	COG0802	atpase or kinase
BF9343_RS03040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BF9343_RS03050	COG2234	aminopeptidase activity
BF9343_RS03070	COG1629	transport
BF9343_RS03090	COG3250	beta-galactosidase activity
BF9343_RS03095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BF9343_RS03105	COG0784	Response regulator, receiver
BF9343_RS03105	COG2205	protein histidine kinase activity
BF9343_RS03130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BF9343_RS03145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BF9343_RS03150	COG0742	ribosomal rna small subunit methyltransferase
BF9343_RS03175	COG4771	TonB-dependent receptor
BF9343_RS03185	COG3537	Alpha-1,2-mannosidase
BF9343_RS03200	COG3537	Alpha-1,2-mannosidase
BF9343_RS03205	COG2814	Major facilitator Superfamily
BF9343_RS03215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF9343_RS03220	COG0739	heme binding
BF9343_RS03230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF9343_RS03235	COG1388	LysM domain
BF9343_RS03235	COG3942	CHAP domain
BF9343_RS03245	COG1475	DNA binding
BF9343_RS03250	COG1192	Involved in chromosome partitioning
BF9343_RS03255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BF9343_RS03260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BF9343_RS03270	COG4589	Belongs to the CDS family
BF9343_RS03275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BF9343_RS03280	COG0799	negative regulation of ribosome biogenesis
BF9343_RS03295	COG2239	Acts as a magnesium transporter
BF9343_RS03300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BF9343_RS03310	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF9343_RS03380	COG0668	transmembrane transport
BF9343_RS03385	COG2207	Transcriptional regulator
BF9343_RS03385	COG0662	Cupin 2, conserved barrel domain protein
BF9343_RS03430	COG1086	Polysaccharide biosynthesis protein
BF9343_RS03435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF9343_RS03445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BF9343_RS03480	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF9343_RS03485	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BF9343_RS03510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF9343_RS03525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF9343_RS03540	COG0667	Aldo Keto reductase
BF9343_RS03545	COG1472	Belongs to the glycosyl hydrolase 3 family
BF9343_RS03550	COG4771	TonB-dependent receptor
BF9343_RS03555	COG0702	epimerase
BF9343_RS03595	COG5012	cobalamin binding
BF9343_RS03610	COG4124	Belongs to the glycosyl hydrolase 26 family
BF9343_RS03615	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BF9343_RS03620	COG2211	Major facilitator Superfamily
BF9343_RS03625	COG2942	2-epimerase
BF9343_RS03670	COG2202	Pas domain
BF9343_RS03670	COG2205	protein histidine kinase activity
BF9343_RS03680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF9343_RS03685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BF9343_RS03690	COG0713	ATP synthesis coupled electron transport
BF9343_RS03695	COG0839	Belongs to the complex I subunit 6 family
BF9343_RS03705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BF9343_RS03710	COG0649	NAD binding
BF9343_RS03710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF9343_RS03715	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF9343_RS03720	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BF9343_RS03730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF9343_RS03735	COG0569	domain protein
BF9343_RS03740	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BF9343_RS03745	COG1073	alpha beta
BF9343_RS03760	COG3119	arylsulfatase activity
BF9343_RS03775	COG3119	arylsulfatase activity
BF9343_RS03785	COG4771	TonB-dependent receptor
BF9343_RS03790	COG0745	RESPONSE REGULATOR receiver
BF9343_RS03790	COG2205	protein histidine kinase activity
BF9343_RS03790	COG3292	Two component regulator propeller
BF9343_RS03795	COG2271	Major facilitator Superfamily
BF9343_RS03820	COG0805	protein transport
BF9343_RS03825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BF9343_RS03830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BF9343_RS03865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BF9343_RS03875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BF9343_RS03880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BF9343_RS03880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BF9343_RS03885	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BF9343_RS03890	COG1078	dGTPase activity
BF9343_RS03895	COG0284	orotidine-5'-phosphate decarboxylase activity
BF9343_RS03900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BF9343_RS03905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BF9343_RS03915	COG1704	LemA family
BF9343_RS03930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BF9343_RS03935	COG2226	methyltransferase
BF9343_RS03940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BF9343_RS03945	COG1702	phosphate starvation-inducible protein PhoH
BF9343_RS03955	COG2268	Band 7 protein
BF9343_RS03965	COG5434	Belongs to the glycosyl hydrolase 28 family
BF9343_RS03975	COG0101	tRNA pseudouridine synthase activity
BF9343_RS03995	COG3250	beta-galactosidase activity
BF9343_RS04000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF9343_RS04025	COG0457	Tetratricopeptide repeat
BF9343_RS04030	COG2814	Major facilitator Superfamily
BF9343_RS04055	COG0561	phosphatase activity
BF9343_RS04060	COG1629	transport
BF9343_RS04060	COG4206	TonB-dependent receptor
BF9343_RS04070	COG4771	TonB-dependent receptor
BF9343_RS04080	COG1629	transport
BF9343_RS04080	COG4206	TonB-dependent receptor
BF9343_RS04095	COG1629	transport
BF9343_RS04095	COG4206	TonB-dependent receptor
BF9343_RS04100	COG0702	epimerase
BF9343_RS04110	COG0673	inositol 2-dehydrogenase activity
BF9343_RS04135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BF9343_RS04150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BF9343_RS04155	COG0793	Belongs to the peptidase S41A family
BF9343_RS04160	COG2131	deaminase
BF9343_RS04170	COG0339	signal peptide processing
BF9343_RS04180	COG1970	mechanosensitive ion channel activity
BF9343_RS04185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BF9343_RS04185	COG0519	Catalyzes the synthesis of GMP from XMP
BF9343_RS04195	COG4206	TonB-dependent receptor
BF9343_RS04195	COG1629	transport
BF9343_RS04205	COG4206	TonB-dependent receptor
BF9343_RS04205	COG1629	transport
BF9343_RS04210	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BF9343_RS04230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BF9343_RS04250	COG1242	4 iron, 4 sulfur cluster binding
BF9343_RS04260	COG0363	glucosamine-6-phosphate deaminase activity
BF9343_RS04270	COG0009	L-threonylcarbamoyladenylate synthase
BF9343_RS04280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF9343_RS04285	COG0561	phosphatase activity
BF9343_RS04290	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF9343_RS04295	COG2873	o-acetylhomoserine
BF9343_RS04350	COG0297	glycogen (starch) synthase activity
BF9343_RS04355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BF9343_RS04360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BF9343_RS04365	COG0543	2 iron, 2 sulfur cluster binding
BF9343_RS04375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BF9343_RS04380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BF9343_RS04385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BF9343_RS04390	COG0546	phosphoglycolate phosphatase activity
BF9343_RS04395	COG0791	NLP P60 protein
BF9343_RS04410	COG0612	Peptidase, M16
BF9343_RS04415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BF9343_RS04420	COG1597	lipid kinase activity
BF9343_RS04425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BF9343_RS04435	COG1136	(ABC) transporter
BF9343_RS04455	COG2211	Major facilitator Superfamily
BF9343_RS04465	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BF9343_RS04480	COG1674	ftsk spoiiie
BF9343_RS04490	COG0492	ferredoxin-NADP+ reductase activity
BF9343_RS04495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS04525	COG1234	tRNA 3'-trailer cleavage
BF9343_RS04530	COG1595	DNA-templated transcription, initiation
BF9343_RS04545	COG3956	TIGRFAM MazG family protein
BF9343_RS04555	COG0525	valine-tRNA ligase activity
BF9343_RS04560	COG2205	protein histidine kinase activity
BF9343_RS04560	COG2198	Histidine kinase
BF9343_RS04560	COG0784	Response regulator, receiver
BF9343_RS04580	COG4771	TonB-dependent receptor
BF9343_RS04595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BF9343_RS04610	COG1629	transport
BF9343_RS04610	COG4206	TonB-dependent receptor
BF9343_RS04615	COG0702	epimerase
BF9343_RS04620	COG3119	arylsulfatase activity
BF9343_RS04625	COG3119	arylsulfatase activity
BF9343_RS04640	COG0653	protein targeting
BF9343_RS04645	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
BF9343_RS04655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BF9343_RS04675	COG1253	flavin adenine dinucleotide binding
BF9343_RS04685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BF9343_RS04695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BF9343_RS04735	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BF9343_RS04745	COG2226	methyltransferase
BF9343_RS04790	COG0110	maltose O-acetyltransferase activity
BF9343_RS04805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF9343_RS04825	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS04830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS04835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS04850	COG4771	TonB-dependent receptor
BF9343_RS04855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BF9343_RS04860	COG0563	adenylate kinase activity
BF9343_RS04865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BF9343_RS04870	COG1496	oxidoreductase activity
BF9343_RS04890	COG2706	6-phosphogluconolactonase activity
BF9343_RS04925	COG1288	antiporter activity
BF9343_RS04945	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BF9343_RS04970	COG0564	pseudouridine synthase activity
BF9343_RS04985	COG1501	Belongs to the glycosyl hydrolase 31 family
BF9343_RS04990	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS05055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BF9343_RS05120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BF9343_RS05210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BF9343_RS05210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BF9343_RS05255	COG4974	Belongs to the 'phage' integrase family
BF9343_RS05265	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF9343_RS05270	COG2205	protein histidine kinase activity
BF9343_RS05270	COG0784	Response regulator, receiver
BF9343_RS05275	COG2910	NAD(P)H-binding
BF9343_RS05280	COG2176	DNA-directed DNA polymerase activity
BF9343_RS05290	COG4864	UPF0365 protein
BF9343_RS05305	COG0037	tRNA processing
BF9343_RS05315	COG1477	protein flavinylation
BF9343_RS05320	COG1971	Probably functions as a manganese efflux pump
BF9343_RS05335	COG0463	Glycosyl transferase, family 2
BF9343_RS05350	COG0148	phosphopyruvate hydratase activity
BF9343_RS05360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BF9343_RS05365	COG1082	Xylose isomerase domain protein TIM barrel
BF9343_RS05385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BF9343_RS05390	COG0193	aminoacyl-tRNA hydrolase activity
BF9343_RS05395	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BF9343_RS05405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BF9343_RS05410	COG1862	Preprotein translocase
BF9343_RS05420	COG0237	dephospho-CoA kinase activity
BF9343_RS05435	COG0542	response to heat
BF9343_RS05445	COG0583	DNA-binding transcription factor activity
BF9343_RS05450	COG2855	membrane
BF9343_RS05465	COG1595	DNA-templated transcription, initiation
BF9343_RS05480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BF9343_RS05500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BF9343_RS05520	COG0443	Heat shock 70 kDa protein
BF9343_RS05530	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BF9343_RS05535	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BF9343_RS05540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BF9343_RS05555	COG1501	Belongs to the glycosyl hydrolase 31 family
BF9343_RS05580	COG1629	transport
BF9343_RS05580	COG4206	TonB-dependent receptor
BF9343_RS05590	COG1408	metallophosphoesterase
BF9343_RS05595	COG1368	sulfuric ester hydrolase activity
BF9343_RS05605	COG3634	alkyl hydroperoxide reductase activity
BF9343_RS05640	COG1760	l-serine dehydratase
BF9343_RS05645	COG0598	Magnesium transport protein CorA
BF9343_RS05650	COG1193	negative regulation of DNA recombination
BF9343_RS05660	COG4974	Belongs to the 'phage' integrase family
BF9343_RS05670	COG2003	Belongs to the UPF0758 family
BF9343_RS05830	COG0551	DNA topoisomerase type I activity
BF9343_RS05830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF9343_RS05855	COG0534	Mate efflux family protein
BF9343_RS05885	COG0546	phosphoglycolate phosphatase activity
BF9343_RS05895	COG2207	Transcriptional regulator
BF9343_RS05915	COG1063	alcohol dehydrogenase
BF9343_RS05930	COG3119	arylsulfatase activity
BF9343_RS05935	COG5002	protein histidine kinase activity
BF9343_RS05940	COG2855	membrane
BF9343_RS05945	COG2217	Heavy metal translocating P-type atpase
BF9343_RS05955	COG2885	chlorophyll binding
BF9343_RS05960	COG3189	MarR family transcriptional regulator
BF9343_RS05965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BF9343_RS05970	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF9343_RS05975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BF9343_RS05995	COG4651	solute:proton antiporter activity
BF9343_RS05995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF9343_RS06000	COG1280	lysine exporter protein (LysE YggA)
BF9343_RS06015	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BF9343_RS06020	COG0561	phosphatase activity
BF9343_RS06025	COG1169	isochorismate synthase
BF9343_RS06030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BF9343_RS06045	COG4948	Mandelate Racemase Muconate Lactonizing
BF9343_RS06060	COG1082	Xylose isomerase domain protein TIM barrel
BF9343_RS06075	COG4771	TonB-dependent receptor
BF9343_RS06105	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BF9343_RS06110	COG0783	Belongs to the Dps family
BF9343_RS06115	COG0583	DNA-binding transcription factor activity
BF9343_RS06135	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF9343_RS06180	COG1253	flavin adenine dinucleotide binding
BF9343_RS06185	COG0501	Belongs to the peptidase M48B family
BF9343_RS06210	COG2873	o-acetylhomoserine
BF9343_RS06215	COG0482	sulfurtransferase activity
BF9343_RS06220	COG2197	response regulator
BF9343_RS06230	COG1757	Na H antiporter
BF9343_RS06245	COG2814	Major facilitator Superfamily
BF9343_RS06250	COG4953	penicillin-binding protein 1C
BF9343_RS06255	COG2373	Large extracellular alpha-helical protein
BF9343_RS06265	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF9343_RS06265	COG1918	ferrous iron import across plasma membrane
BF9343_RS06320	COG2244	polysaccharide biosynthetic process
BF9343_RS06325	COG0562	UDP-galactopyranose mutase
BF9343_RS06330	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS06345	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS06355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BF9343_RS06360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF9343_RS06370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS06375	COG0471	metal ion transport
BF9343_RS06375	COG0490	domain, Protein
BF9343_RS06390	COG0346	lactoylglutathione lyase activity
BF9343_RS06405	COG0259	pyridoxamine-phosphate oxidase activity
BF9343_RS06410	COG1741	Belongs to the pirin family
BF9343_RS06425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF9343_RS06455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BF9343_RS06460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BF9343_RS06465	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BF9343_RS06480	COG1595	DNA-templated transcription, initiation
BF9343_RS06505	COG0686	Belongs to the AlaDH PNT family
BF9343_RS06520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF9343_RS06535	COG1629	transport
BF9343_RS06550	COG3345	alpha-galactosidase
BF9343_RS06570	COG0488	(ABC) transporter
BF9343_RS06575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BF9343_RS06580	COG3059	membrane
BF9343_RS06585	COG1917	Cupin 2, conserved barrel domain protein
BF9343_RS06585	COG2207	Transcriptional regulator
BF9343_RS06590	COG0295	cytidine deaminase activity
BF9343_RS06595	COG1388	LysM domain
BF9343_RS06595	COG1705	Flagellar rod assembly protein muramidase FlgJ
BF9343_RS06610	COG0577	efflux transmembrane transporter activity
BF9343_RS06620	COG0577	efflux transmembrane transporter activity
BF9343_RS06630	COG1136	(ABC) transporter
BF9343_RS06630	COG0577	efflux transmembrane transporter activity
BF9343_RS06645	COG1136	(ABC) transporter
BF9343_RS06660	COG1136	(ABC) transporter
BF9343_RS06680	COG0784	Response regulator, receiver
BF9343_RS06680	COG2205	protein histidine kinase activity
BF9343_RS06745	COG0732	type I restriction modification DNA specificity domain
BF9343_RS06900	COG0739	heme binding
BF9343_RS06900	COG1196	nuclear chromosome segregation
BF9343_RS06900	COG0741	lytic transglycosylase activity
BF9343_RS06930	COG1192	Involved in chromosome partitioning
BF9343_RS06940	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BF9343_RS06965	COG0702	epimerase
BF9343_RS06970	COG4771	TonB-dependent receptor
BF9343_RS07090	COG4974	Belongs to the 'phage' integrase family
BF9343_RS07155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS07160	COG2244	polysaccharide biosynthetic process
BF9343_RS07170	COG1216	Glycosyl transferase, family 2
BF9343_RS07170	COG1442	glycosyl transferase family 8
BF9343_RS07195	COG0463	Glycosyl transferase, family 2
BF9343_RS07205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS07210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS07215	COG1530	ribonuclease E activity
BF9343_RS07230	COG3119	arylsulfatase activity
BF9343_RS07235	COG0629	single-stranded DNA binding
BF9343_RS07290	COG4206	TonB-dependent receptor
BF9343_RS07310	COG5002	protein histidine kinase activity
BF9343_RS07315	COG0745	RESPONSE REGULATOR receiver
BF9343_RS07340	COG0488	(ABC) transporter
BF9343_RS07355	COG5492	domain, Protein
BF9343_RS07365	COG0436	Aminotransferase
BF9343_RS07370	COG4591	ABC-type transport system involved in lipoprotein release permease component
BF9343_RS07375	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS07380	COG0628	permease
BF9343_RS07385	COG3852	Histidine kinase
BF9343_RS07400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS07410	COG1136	(ABC) transporter
BF9343_RS07410	COG0577	efflux transmembrane transporter activity
BF9343_RS07415	COG0577	efflux transmembrane transporter activity
BF9343_RS07420	COG1252	NADH dehydrogenase
BF9343_RS07440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BF9343_RS07440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BF9343_RS07450	COG4771	TonB-dependent receptor
BF9343_RS07460	COG1620	l-lactate permease
BF9343_RS07465	COG2885	chlorophyll binding
BF9343_RS07465	COG3047	cAMP biosynthetic process
BF9343_RS07475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF9343_RS07480	COG0439	Biotin carboxylase
BF9343_RS07485	COG0511	ligase activity, forming carbon-carbon bonds
BF9343_RS07490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BF9343_RS07525	COG0508	dehydrogenase complex catalyzes the overall conversion of
BF9343_RS07530	COG0022	dehydrogenase e1 component
BF9343_RS07535	COG0716	FMN binding
BF9343_RS07540	COG2264	protein methyltransferase activity
BF9343_RS07580	COG0590	tRNA wobble adenosine to inosine editing
BF9343_RS07605	COG0673	inositol 2-dehydrogenase activity
BF9343_RS07610	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BF9343_RS07645	COG0698	ribose 5-phosphate isomerase
BF9343_RS07650	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BF9343_RS07655	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BF9343_RS07670	COG1482	cell wall glycoprotein biosynthetic process
BF9343_RS07690	COG0513	Belongs to the DEAD box helicase family
BF9343_RS07695	COG4221	oxidoreductase activity
BF9343_RS07710	COG3250	beta-galactosidase activity
BF9343_RS07720	COG3273	potassium ion transport
BF9343_RS07720	COG0471	metal ion transport
BF9343_RS07725	COG0529	Catalyzes the synthesis of activated sulfate
BF9343_RS07730	COG0175	sulfate reduction
BF9343_RS07735	COG2895	sulfate adenylyltransferase (ATP) activity
BF9343_RS07775	COG4974	Belongs to the 'phage' integrase family
BF9343_RS07800	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BF9343_RS07805	COG0242	peptide deformylase activity
BF9343_RS07820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BF9343_RS07825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BF9343_RS07830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BF9343_RS07835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BF9343_RS07845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BF9343_RS07850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BF9343_RS07865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BF9343_RS07910	COG1940	carbohydrate kinase activity
BF9343_RS07915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF9343_RS07925	COG2271	Major facilitator Superfamily
BF9343_RS07930	COG2731	YhcH YjgK YiaL family protein
BF9343_RS07940	COG0702	epimerase
BF9343_RS07945	COG4206	TonB-dependent receptor
BF9343_RS07945	COG1629	transport
BF9343_RS07950	COG0702	epimerase
BF9343_RS07955	COG0702	epimerase
BF9343_RS07960	COG4771	TonB-dependent receptor
BF9343_RS08035	COG0551	DNA topoisomerase type I activity
BF9343_RS08035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BF9343_RS08045	COG4974	Belongs to the 'phage' integrase family
BF9343_RS08250	COG2003	Belongs to the UPF0758 family
BF9343_RS08270	COG1475	DNA binding
BF9343_RS08320	COG1733	regulation of RNA biosynthetic process
BF9343_RS08355	COG0702	epimerase
BF9343_RS08360	COG1629	transport
BF9343_RS08375	COG0702	epimerase
BF9343_RS08380	COG1629	transport
BF9343_RS08385	COG4206	TonB-dependent receptor
BF9343_RS08385	COG1629	transport
BF9343_RS08400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS08420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS08430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS08435	COG3537	Alpha-1,2-mannosidase
BF9343_RS08440	COG3250	beta-galactosidase activity
BF9343_RS08445	COG4206	TonB-dependent receptor
BF9343_RS08445	COG1629	transport
BF9343_RS08450	COG0702	epimerase
BF9343_RS08455	COG0484	heat shock protein binding
BF9343_RS08460	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BF9343_RS08465	COG0488	(ABC) transporter
BF9343_RS08470	COG1595	DNA-templated transcription, initiation
BF9343_RS08540	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BF9343_RS08570	COG0732	type I restriction modification DNA specificity domain
BF9343_RS08575	COG0582	viral genome integration into host DNA
BF9343_RS08595	COG2885	chlorophyll binding
BF9343_RS08710	COG2183	response to ionizing radiation
BF9343_RS08715	COG2205	protein histidine kinase activity
BF9343_RS08720	COG0737	Belongs to the 5'-nucleotidase family
BF9343_RS08725	COG1956	GAF domain-containing protein
BF9343_RS08735	COG4771	TonB-dependent receptor
BF9343_RS08760	COG0534	Mate efflux family protein
BF9343_RS08770	COG0534	Mate efflux family protein
BF9343_RS08780	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BF9343_RS08790	COG0318	PFAM AMP-dependent synthetase and ligase
BF9343_RS08795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS08800	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BF9343_RS08840	COG4750	Nucleotidyl transferase
BF9343_RS08855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF9343_RS08885	COG1216	Glycosyl transferase, family 2
BF9343_RS08890	COG1216	Glycosyl transferase, family 2
BF9343_RS08905	COG1086	Polysaccharide biosynthesis protein
BF9343_RS08915	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF9343_RS08925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS08930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS08945	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BF9343_RS08950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BF9343_RS08955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BF9343_RS08960	COG0363	glucosamine-6-phosphate deaminase activity
BF9343_RS08980	COG4413	Urea transporter
BF9343_RS09010	COG3279	Response regulator of the LytR AlgR family
BF9343_RS09020	COG1136	(ABC) transporter
BF9343_RS09020	COG0577	efflux transmembrane transporter activity
BF9343_RS09025	COG1136	(ABC) transporter
BF9343_RS09030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS09055	COG4884	unkown
BF9343_RS09055	COG3831	ATPase activity
BF9343_RS09070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF9343_RS09080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BF9343_RS09085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BF9343_RS09090	COG3250	beta-galactosidase activity
BF9343_RS09115	COG0501	Belongs to the peptidase M48B family
BF9343_RS09120	COG1704	LemA family
BF9343_RS09125	COG1595	DNA-templated transcription, initiation
BF9343_RS09135	COG4206	TonB-dependent receptor
BF9343_RS09135	COG1629	transport
BF9343_RS09145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BF9343_RS09150	COG2885	chlorophyll binding
BF9343_RS09150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BF9343_RS09160	COG0697	spore germination
BF9343_RS09190	COG0776	regulation of translation
BF9343_RS09250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF9343_RS09265	COG1846	Transcriptional regulator
BF9343_RS09265	COG0456	acetyltransferase
BF9343_RS09270	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BF9343_RS09275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF9343_RS09280	COG2814	Major facilitator Superfamily
BF9343_RS09285	COG4771	TonB-dependent receptor
BF9343_RS09310	COG4771	TonB-dependent receptor
BF9343_RS09465	COG0542	response to heat
BF9343_RS09490	COG0156	8-amino-7-oxononanoate synthase activity
BF9343_RS09565	COG0488	(ABC) transporter
BF9343_RS09585	COG2198	Histidine kinase
BF9343_RS09585	COG2205	protein histidine kinase activity
BF9343_RS09585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF9343_RS09585	COG0784	Response regulator, receiver
BF9343_RS09610	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS09625	COG2244	polysaccharide biosynthetic process
BF9343_RS09630	COG1442	glycosyl transferase family 8
BF9343_RS09630	COG1216	Glycosyl transferase, family 2
BF9343_RS09640	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS09675	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BF9343_RS09680	COG1805	sodium ion transport
BF9343_RS09685	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BF9343_RS09710	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BF9343_RS09715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BF9343_RS09725	COG0545	Peptidyl-prolyl cis-trans isomerase
BF9343_RS09730	COG1739	Uncharacterized protein family UPF0029
BF9343_RS09740	COG0778	Nitroreductase
BF9343_RS09745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BF9343_RS09745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BF9343_RS09750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BF9343_RS09780	COG2217	Heavy metal translocating P-type atpase
BF9343_RS09790	COG0321	lipoyl(octanoyl) transferase activity
BF9343_RS09820	COG3852	Histidine kinase
BF9343_RS09825	COG2204	response regulator
BF9343_RS09845	COG1136	(ABC) transporter
BF9343_RS09855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BF9343_RS09860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF9343_RS09865	COG1755	Isoprenylcysteine carboxyl methyltransferase
BF9343_RS09875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BF9343_RS09890	COG1678	Uncharacterized ACR, COG1678
BF9343_RS09955	COG0667	Aldo Keto reductase
BF9343_RS09970	COG0667	Aldo Keto reductase
BF9343_RS09980	COG0656	L-ascorbic acid biosynthetic process
BF9343_RS09990	COG0656	L-ascorbic acid biosynthetic process
BF9343_RS09995	COG0656	L-ascorbic acid biosynthetic process
BF9343_RS10010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BF9343_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS10045	COG1979	alcohol dehydrogenase
BF9343_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS10070	COG0667	Aldo Keto reductase
BF9343_RS10085	COG2311	Membrane
BF9343_RS10090	COG0667	Aldo Keto reductase
BF9343_RS10155	COG4771	TonB-dependent receptor
BF9343_RS10180	COG1309	transcriptional regulator
BF9343_RS10195	COG1132	(ABC) transporter
BF9343_RS10200	COG2205	protein histidine kinase activity
BF9343_RS10215	COG1522	sequence-specific DNA binding
BF9343_RS10235	COG3969	phosphoadenosine phosphosulfate
BF9343_RS10240	COG1475	DNA binding
BF9343_RS10280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS10285	COG0745	RESPONSE REGULATOR receiver
BF9343_RS10300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS10310	COG4206	TonB-dependent receptor
BF9343_RS10310	COG1629	transport
BF9343_RS10320	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BF9343_RS10340	COG1022	Amp-dependent synthetase and ligase
BF9343_RS10345	COG3263	regulation of cellular component size
BF9343_RS10355	COG1151	hydroxylamine reductase activity
BF9343_RS10390	COG1136	(ABC) transporter
BF9343_RS10390	COG0577	efflux transmembrane transporter activity
BF9343_RS10400	COG1136	(ABC) transporter
BF9343_RS10400	COG0577	efflux transmembrane transporter activity
BF9343_RS10415	COG0534	Mate efflux family protein
BF9343_RS10420	COG1011	Hydrolase
BF9343_RS10425	COG0167	dihydroorotate dehydrogenase activity
BF9343_RS10435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BF9343_RS10450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BF9343_RS10465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BF9343_RS10475	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BF9343_RS10485	COG0356	it plays a direct role in the translocation of protons across the membrane
BF9343_RS10490	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BF9343_RS10495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BF9343_RS10500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BF9343_RS10505	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BF9343_RS10510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BF9343_RS10515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BF9343_RS10520	COG3118	belongs to the thioredoxin family
BF9343_RS10540	COG0745	RESPONSE REGULATOR receiver
BF9343_RS10545	COG5002	protein histidine kinase activity
BF9343_RS10575	COG1120	ATPase activity
BF9343_RS10580	COG1091	dTDP-4-dehydrorhamnose reductase activity
BF9343_RS10610	COG2205	protein histidine kinase activity
BF9343_RS10615	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BF9343_RS10625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BF9343_RS10640	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BF9343_RS10645	COG0540	Belongs to the ATCase OTCase family
BF9343_RS10655	COG2431	L-lysine efflux transmembrane transporter activity
BF9343_RS10680	COG2837	iron assimilation
BF9343_RS10690	COG4206	TonB-dependent receptor
BF9343_RS10690	COG1629	transport
BF9343_RS10710	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BF9343_RS10720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BF9343_RS10740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BF9343_RS10745	COG2205	protein histidine kinase activity
BF9343_RS10975	COG0629	single-stranded DNA binding
BF9343_RS10980	COG0358	DNA primase activity
BF9343_RS11035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF9343_RS11040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF9343_RS11050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BF9343_RS11060	COG0673	inositol 2-dehydrogenase activity
BF9343_RS11070	COG2223	nitrite transmembrane transporter activity
BF9343_RS11090	COG0671	phosphoesterase, PA-phosphatase related
BF9343_RS11100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BF9343_RS11105	COG0045	succinate-CoA ligase (ADP-forming) activity
BF9343_RS11110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BF9343_RS11115	COG0351	phosphomethylpyrimidine kinase
BF9343_RS11125	COG1070	Carbohydrate kinase
BF9343_RS11130	COG2115	Belongs to the xylose isomerase family
BF9343_RS11135	COG0477	Major facilitator Superfamily
BF9343_RS11135	COG2814	Major facilitator Superfamily
BF9343_RS11145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF9343_RS11145	COG3153	acetyltransferase
BF9343_RS11150	COG0450	alkyl hydroperoxide reductase
BF9343_RS11155	COG0724	RNA recognition motif
BF9343_RS11160	COG1858	cytochrome C peroxidase
BF9343_RS11165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BF9343_RS11185	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BF9343_RS11195	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BF9343_RS11210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF9343_RS11260	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF9343_RS11270	COG1904	glucuronate isomerase
BF9343_RS11300	COG0513	Belongs to the DEAD box helicase family
BF9343_RS11305	COG0560	Phosphoserine phosphatase
BF9343_RS11305	COG3830	Belongs to the UPF0237 family
BF9343_RS11320	COG0343	queuine tRNA-ribosyltransferase activity
BF9343_RS11325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BF9343_RS11330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BF9343_RS11605	COG2205	protein histidine kinase activity
BF9343_RS11610	COG2204	response regulator
BF9343_RS11655	COG1136	(ABC) transporter
BF9343_RS11655	COG0577	efflux transmembrane transporter activity
BF9343_RS11665	COG0156	8-amino-7-oxononanoate synthase activity
BF9343_RS11670	COG1597	lipid kinase activity
BF9343_RS11675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BF9343_RS11700	COG0577	efflux transmembrane transporter activity
BF9343_RS11700	COG1136	(ABC) transporter
BF9343_RS11725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BF9343_RS11755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF9343_RS11770	COG0543	2 iron, 2 sulfur cluster binding
BF9343_RS11775	COG0167	dihydroorotate dehydrogenase activity
BF9343_RS11780	COG0336	Belongs to the RNA methyltransferase TrmD family
BF9343_RS11785	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BF9343_RS11790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF9343_RS11800	COG2315	Protein conserved in bacteria
BF9343_RS11830	COG0326	Molecular chaperone. Has ATPase activity
BF9343_RS11835	COG0542	response to heat
BF9343_RS11880	COG2304	oxidoreductase activity
BF9343_RS11895	COG0714	Associated with various cellular activities
BF9343_RS11900	COG1652	LysM domain
BF9343_RS11910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF9343_RS11915	COG0552	protein localization to endoplasmic reticulum
BF9343_RS11920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BF9343_RS11925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BF9343_RS11930	COG1546	Belongs to the CinA family
BF9343_RS11930	COG1058	Belongs to the CinA family
BF9343_RS11935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BF9343_RS11950	COG0442	prolyl-tRNA aminoacylation
BF9343_RS11960	COG0793	Belongs to the peptidase S41A family
BF9343_RS11960	COG4946	Tricorn protease homolog
BF9343_RS11970	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BF9343_RS11975	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BF9343_RS11990	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BF9343_RS12000	COG1492	cobalamin metabolic process
BF9343_RS12045	COG0784	Response regulator, receiver
BF9343_RS12045	COG2198	Histidine kinase
BF9343_RS12045	COG5002	protein histidine kinase activity
BF9343_RS12050	COG2096	Adenosyltransferase
BF9343_RS12055	COG1797	cobyrinic acid a,c-diamide synthase activity
BF9343_RS12070	COG2966	Psort location CytoplasmicMembrane, score
BF9343_RS12080	COG4771	TonB-dependent receptor
BF9343_RS12090	COG4774	siderophore transport
BF9343_RS12100	COG1429	ligase activity, forming nitrogen-metal bonds
BF9343_RS12135	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BF9343_RS12210	COG0352	thiamine-phosphate diphosphorylase activity
BF9343_RS12215	COG2022	thiamine diphosphate biosynthetic process
BF9343_RS12220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BF9343_RS12240	COG0352	thiamine-phosphate diphosphorylase activity
BF9343_RS12255	COG0574	Belongs to the PEP-utilizing enzyme family
BF9343_RS12255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BF9343_RS12260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BF9343_RS12265	COG0564	pseudouridine synthase activity
BF9343_RS12280	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BF9343_RS12300	COG0024	Methionine aminopeptidase
BF9343_RS12315	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BF9343_RS12325	COG0481	GTPase activity
BF9343_RS12345	COG0708	Exodeoxyribonuclease III
BF9343_RS12350	COG1914	H( )-stimulated, divalent metal cation uptake system
BF9343_RS12365	COG0217	transcriptional regulatory protein
BF9343_RS12370	COG0072	phenylalanine-tRNA ligase activity
BF9343_RS12370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF9343_RS12375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS12380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS12385	COG0297	glycogen (starch) synthase activity
BF9343_RS12390	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS12395	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS12405	COG1216	Glycosyl transferase, family 2
BF9343_RS12415	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS12420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS12465	COG0305	Participates in initiation and elongation during chromosome replication
BF9343_RS12470	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BF9343_RS12485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BF9343_RS12490	COG4657	Part of a membrane complex involved in electron transport
BF9343_RS12495	COG4660	Part of a membrane complex involved in electron transport
BF9343_RS12500	COG4659	FMN binding
BF9343_RS12505	COG4658	electron transport chain
BF9343_RS12510	COG4656	Part of a membrane complex involved in electron transport
BF9343_RS12535	COG0504	CTP synthase activity
BF9343_RS12540	COG0706	membrane insertase activity
BF9343_RS12545	COG0534	Mate efflux family protein
BF9343_RS12550	COG1506	peptidase
BF9343_RS12550	COG0823	Involved in the tonB-independent uptake of proteins
BF9343_RS12565	COG1695	Transcriptional regulator
BF9343_RS12580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BF9343_RS12590	COG3942	CHAP domain
BF9343_RS12590	COG1388	LysM domain
BF9343_RS12620	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BF9343_RS12625	COG0556	nucleotide-excision repair
BF9343_RS12630	COG2949	membrane
BF9343_RS12640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BF9343_RS12650	COG0784	Response regulator, receiver
BF9343_RS12650	COG2205	protein histidine kinase activity
BF9343_RS12660	COG0842	Transport permease protein
BF9343_RS12665	COG1131	(ABC) transporter
BF9343_RS12695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BF9343_RS12700	COG0505	Belongs to the CarA family
BF9343_RS12710	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BF9343_RS12715	COG0367	asparagine synthase
BF9343_RS12740	COG0436	Aminotransferase
BF9343_RS12750	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF9343_RS12760	COG1979	alcohol dehydrogenase
BF9343_RS12770	COG0133	tryptophan synthase activity
BF9343_RS12775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BF9343_RS12780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF9343_RS12780	COG0512	Glutamine amidotransferase of anthranilate synthase
BF9343_RS12785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BF9343_RS12790	COG0134	indole-3-glycerol-phosphate synthase activity
BF9343_RS12795	COG0135	phosphoribosylanthranilate isomerase activity
BF9343_RS12800	COG0159	tryptophan synthase activity
BF9343_RS12805	COG0252	asparaginase activity
BF9343_RS12820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BF9343_RS12830	COG0110	maltose O-acetyltransferase activity
BF9343_RS12835	COG2197	response regulator
BF9343_RS12845	COG0138	bifunctional purine biosynthesis protein purh
BF9343_RS12850	COG0716	FMN binding
BF9343_RS12875	COG1858	cytochrome C peroxidase
BF9343_RS12885	COG4771	TonB-dependent receptor
BF9343_RS12895	COG2814	Major facilitator Superfamily
BF9343_RS12900	COG1566	PFAM secretion protein HlyD family protein
BF9343_RS12930	COG4771	TonB-dependent receptor
BF9343_RS12955	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF9343_RS12960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BF9343_RS12970	COG2966	Psort location CytoplasmicMembrane, score
BF9343_RS12975	COG3610	response to peptide
BF9343_RS12990	COG1609	Transcriptional regulator
BF9343_RS13000	COG1733	regulation of RNA biosynthetic process
BF9343_RS13005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BF9343_RS13005	COG2205	protein histidine kinase activity
BF9343_RS13005	COG2198	Histidine kinase
BF9343_RS13005	COG0784	Response regulator, receiver
BF9343_RS13025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BF9343_RS13030	COG1690	Belongs to the RtcB family
BF9343_RS13050	COG0228	four-way junction DNA binding
BF9343_RS13065	COG0724	RNA recognition motif
BF9343_RS13075	COG1177	transmembrane transport
BF9343_RS13080	COG1176	ABC-type spermidine putrescine transport system, permease component I
BF9343_RS13085	COG3842	ATPase activity
BF9343_RS13090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS13100	COG0058	SHG alpha-glucan phosphorylase activity
BF9343_RS13110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BF9343_RS13130	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BF9343_RS13180	COG0745	RESPONSE REGULATOR receiver
BF9343_RS13185	COG5002	protein histidine kinase activity
BF9343_RS13210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BF9343_RS13215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BF9343_RS13225	COG4948	Mandelate Racemase Muconate Lactonizing
BF9343_RS13235	COG1295	ribonuclease BN
BF9343_RS13240	COG0778	Nitroreductase
BF9343_RS13250	COG0704	Plays a role in the regulation of phosphate uptake
BF9343_RS13255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BF9343_RS13260	COG0581	inorganic phosphate transmembrane transporter activity
BF9343_RS13265	COG0573	inorganic phosphate transmembrane transporter activity
BF9343_RS13275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BF9343_RS13295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BF9343_RS13330	COG3023	N-Acetylmuramoyl-L-alanine amidase
BF9343_RS13380	COG1216	Glycosyl transferase, family 2
BF9343_RS13385	COG1216	Glycosyl transferase, family 2
BF9343_RS13390	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS13410	COG1216	Glycosyl transferase, family 2
BF9343_RS13420	COG1045	serine acetyltransferase
BF9343_RS13425	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS13445	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BF9343_RS13495	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BF9343_RS13525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BF9343_RS13530	COG0167	dihydroorotate dehydrogenase activity
BF9343_RS13595	COG5002	protein histidine kinase activity
BF9343_RS13610	COG2172	sigma factor antagonist activity
BF9343_RS13620	COG2208	phosphoserine phosphatase activity
BF9343_RS13645	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BF9343_RS13665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BF9343_RS13670	COG0497	DNA recombination
BF9343_RS13680	COG5002	protein histidine kinase activity
BF9343_RS13680	COG2176	DNA-directed DNA polymerase activity
BF9343_RS13685	COG0592	DNA-directed DNA polymerase activity
BF9343_RS13700	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BF9343_RS13700	COG0321	lipoyl(octanoyl) transferase activity
BF9343_RS13705	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BF9343_RS13715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS13720	COG0156	8-amino-7-oxononanoate synthase activity
BF9343_RS13810	COG0019	diaminopimelate decarboxylase activity
BF9343_RS13815	COG0527	aspartate kinase activity
BF9343_RS13820	COG2884	Cell division ATP-binding protein ftsE
BF9343_RS13825	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BF9343_RS13825	COG0140	phosphoribosyl-ATP diphosphatase activity
BF9343_RS13830	COG0107	imidazoleglycerol-phosphate synthase activity
BF9343_RS13835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BF9343_RS13840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BF9343_RS13855	COG3586	endonuclease activity
BF9343_RS13890	COG1472	Belongs to the glycosyl hydrolase 3 family
BF9343_RS13895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BF9343_RS13905	COG5012	cobalamin binding
BF9343_RS13915	COG1472	Belongs to the glycosyl hydrolase 3 family
BF9343_RS13920	COG0702	epimerase
BF9343_RS13925	COG4771	TonB-dependent receptor
BF9343_RS13950	COG0693	protein deglycase activity
BF9343_RS13955	COG0494	nUDIX hydrolase
BF9343_RS13960	COG1401	restriction endodeoxyribonuclease activity
BF9343_RS13975	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BF9343_RS14020	COG4977	sequence-specific DNA binding
BF9343_RS14020	COG1917	Cupin 2, conserved barrel domain protein
BF9343_RS14025	COG2814	Major facilitator Superfamily
BF9343_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS14035	COG2207	Transcriptional regulator
BF9343_RS14050	COG1090	epimerase
BF9343_RS14080	COG0561	phosphatase activity
BF9343_RS14085	COG4206	TonB-dependent receptor
BF9343_RS14085	COG1629	transport
BF9343_RS14135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF9343_RS14145	COG0363	glucosamine-6-phosphate deaminase activity
BF9343_RS14185	COG1032	radical SAM domain protein
BF9343_RS14190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BF9343_RS14195	COG0463	Glycosyl transferase, family 2
BF9343_RS14200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BF9343_RS14210	COG1410	methionine synthase
BF9343_RS14210	COG0646	methionine synthase
BF9343_RS14265	COG1408	metallophosphoesterase
BF9343_RS14270	COG1132	(ABC) transporter
BF9343_RS14275	COG1132	(ABC) transporter
BF9343_RS14290	COG0420	3'-5' exonuclease activity
BF9343_RS14310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF9343_RS14315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS14325	COG0681	Belongs to the peptidase S26 family
BF9343_RS14405	COG0641	radical SAM
BF9343_RS14410	COG3591	Belongs to the peptidase S1B family
BF9343_RS14415	COG3591	Belongs to the peptidase S1B family
BF9343_RS14450	COG1592	Rubrerythrin
BF9343_RS14450	COG1773	rubredoxin
BF9343_RS14460	COG3152	Membrane
BF9343_RS14465	COG0339	signal peptide processing
BF9343_RS14470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BF9343_RS14470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BF9343_RS14480	COG1629	transport
BF9343_RS14480	COG4206	TonB-dependent receptor
BF9343_RS14495	COG0131	Imidazoleglycerol-phosphate dehydratase
BF9343_RS14495	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BF9343_RS14500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF9343_RS14505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BF9343_RS14510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BF9343_RS14520	COG1741	Belongs to the pirin family
BF9343_RS14525	COG4232	protein-disulfide reductase activity
BF9343_RS14535	COG0572	uridine kinase
BF9343_RS14545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BF9343_RS14555	COG1410	methionine synthase
BF9343_RS14555	COG0646	methionine synthase
BF9343_RS14560	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BF9343_RS14595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF9343_RS14605	COG1295	ribonuclease BN
BF9343_RS14630	COG2205	protein histidine kinase activity
BF9343_RS14630	COG2202	Pas domain
BF9343_RS14635	COG0534	Mate efflux family protein
BF9343_RS14640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BF9343_RS14650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS14655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BF9343_RS14660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS14720	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BF9343_RS14760	COG2195	Cleaves the N-terminal amino acid of tripeptides
BF9343_RS14770	COG0668	transmembrane transport
BF9343_RS14775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BF9343_RS14785	COG3250	beta-galactosidase activity
BF9343_RS14790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS14795	COG3119	arylsulfatase activity
BF9343_RS14800	COG3119	arylsulfatase activity
BF9343_RS14805	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS14810	COG3292	Two component regulator propeller
BF9343_RS14810	COG2205	protein histidine kinase activity
BF9343_RS14810	COG0745	RESPONSE REGULATOR receiver
BF9343_RS14815	COG1830	Aldolase
BF9343_RS14820	COG0588	phosphoglycerate mutase activity
BF9343_RS14830	COG1119	ATPase activity
BF9343_RS14835	COG3119	arylsulfatase activity
BF9343_RS14840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS14850	COG4206	TonB-dependent receptor
BF9343_RS14850	COG1629	transport
BF9343_RS14860	COG1595	DNA-templated transcription, initiation
BF9343_RS14865	COG1523	belongs to the glycosyl hydrolase 13 family
BF9343_RS14870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BF9343_RS14890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BF9343_RS14900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BF9343_RS14905	COG0126	phosphoglycerate kinase activity
BF9343_RS14920	COG2311	Membrane
BF9343_RS14965	COG0424	maF-like protein
BF9343_RS14970	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BF9343_RS14985	COG0778	Nitroreductase
BF9343_RS14990	COG0288	reversible hydration of carbon dioxide
BF9343_RS15005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF9343_RS15015	COG5016	pyruvate
BF9343_RS15015	COG0511	ligase activity, forming carbon-carbon bonds
BF9343_RS15020	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BF9343_RS15035	COG0366	Alpha amylase catalytic
BF9343_RS15055	COG0191	fructose-bisphosphate aldolase activity
BF9343_RS15065	COG0254	rRNA binding
BF9343_RS15090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BF9343_RS15095	COG1629	transport
BF9343_RS15095	COG4206	TonB-dependent receptor
BF9343_RS15100	COG1609	Transcriptional regulator
BF9343_RS15110	COG1554	hydrolase, family 65, central catalytic
BF9343_RS15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS15135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BF9343_RS15135	COG0047	phosphoribosylformylglycinamidine synthase activity
BF9343_RS15140	COG3292	Two component regulator propeller
BF9343_RS15140	COG2205	protein histidine kinase activity
BF9343_RS15140	COG0745	RESPONSE REGULATOR receiver
BF9343_RS15155	COG1649	PFAM Uncharacterised BCR, COG1649
BF9343_RS15175	COG1966	Carbon starvation protein
BF9343_RS15180	COG1649	PFAM Uncharacterised BCR, COG1649
BF9343_RS15185	COG0784	Response regulator, receiver
BF9343_RS15185	COG2205	protein histidine kinase activity
BF9343_RS15220	COG2113	Glycine betaine
BF9343_RS15225	COG4176	ABC-type proline glycine betaine transport system permease component
BF9343_RS15240	COG3292	Two component regulator propeller
BF9343_RS15240	COG0745	RESPONSE REGULATOR receiver
BF9343_RS15240	COG2205	protein histidine kinase activity
BF9343_RS15245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BF9343_RS15245	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BF9343_RS15255	COG1621	beta-fructofuranosidase activity
BF9343_RS15280	COG0738	Major facilitator superfamily
BF9343_RS15295	COG1752	Esterase of the alpha-beta hydrolase superfamily
BF9343_RS15300	COG0475	glutathione-regulated potassium exporter activity
BF9343_RS15325	COG3015	lipoprotein NlpE involved in copper resistance
BF9343_RS15345	COG4977	sequence-specific DNA binding
BF9343_RS15345	COG1917	Cupin 2, conserved barrel domain protein
BF9343_RS15370	COG4771	TonB-dependent receptor
BF9343_RS15375	COG0702	epimerase
BF9343_RS15390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BF9343_RS15410	COG0484	heat shock protein binding
BF9343_RS15415	COG0784	Response regulator, receiver
BF9343_RS15415	COG2205	protein histidine kinase activity
BF9343_RS15420	COG2194	sulfuric ester hydrolase activity
BF9343_RS15465	COG0028	Belongs to the TPP enzyme family
BF9343_RS15490	COG0459	protein refolding
BF9343_RS15495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BF9343_RS15535	COG2326	polyphosphate kinase activity
BF9343_RS15565	COG3537	Alpha-1,2-mannosidase
BF9343_RS15570	COG0823	Involved in the tonB-independent uptake of proteins
BF9343_RS15570	COG1506	peptidase
BF9343_RS15575	COG0124	histidyl-tRNA synthetase
BF9343_RS15600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BF9343_RS15640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF9343_RS15650	COG0671	phosphoesterase, PA-phosphatase related
BF9343_RS15670	COG0702	epimerase
BF9343_RS15675	COG4771	TonB-dependent receptor
BF9343_RS15695	COG0463	Glycosyl transferase, family 2
BF9343_RS15710	COG0066	3-isopropylmalate dehydratase activity
BF9343_RS15715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BF9343_RS15720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BF9343_RS15770	COG0616	signal peptide processing
BF9343_RS15775	COG1663	tetraacyldisaccharide 4'-kinase activity
BF9343_RS15780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BF9343_RS15785	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BF9343_RS15860	COG0667	Aldo Keto reductase
BF9343_RS15900	COG0546	phosphoglycolate phosphatase activity
BF9343_RS15915	COG2207	Transcriptional regulator
BF9343_RS15920	COG2205	protein histidine kinase activity
BF9343_RS15920	COG0745	RESPONSE REGULATOR receiver
BF9343_RS15920	COG3292	Two component regulator propeller
BF9343_RS15925	COG4948	Mandelate Racemase Muconate Lactonizing
BF9343_RS15945	COG0702	epimerase
BF9343_RS15950	COG1629	transport
BF9343_RS15950	COG4206	TonB-dependent receptor
BF9343_RS15975	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BF9343_RS15980	COG1917	Cupin 2, conserved barrel domain protein
BF9343_RS15980	COG2207	Transcriptional regulator
BF9343_RS15995	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BF9343_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
BF9343_RS16075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BF9343_RS16085	COG4651	solute:proton antiporter activity
BF9343_RS16085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BF9343_RS16090	COG0439	Biotin carboxylase
BF9343_RS16095	COG0511	ligase activity, forming carbon-carbon bonds
BF9343_RS16095	COG5016	pyruvate
BF9343_RS16100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BF9343_RS16105	COG1335	isochorismatase
BF9343_RS16115	COG0517	IMP dehydrogenase activity
BF9343_RS16115	COG0516	GMP reductase activity
BF9343_RS16130	COG2207	Transcriptional regulator
BF9343_RS16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS16150	COG2873	o-acetylhomoserine
BF9343_RS16200	COG2076	Multidrug Resistance protein
BF9343_RS16235	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BF9343_RS16245	COG0741	lytic transglycosylase activity
BF9343_RS16245	COG1388	LysM domain
BF9343_RS16250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BF9343_RS16255	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BF9343_RS16255	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BF9343_RS16265	COG1285	pathogenesis
BF9343_RS16285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF9343_RS16285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BF9343_RS16300	COG1115	amino acid carrier protein
BF9343_RS16310	COG1509	lysine 2,3-aminomutase activity
BF9343_RS16315	COG2233	PERMEase
BF9343_RS16330	COG1393	Belongs to the ArsC family
BF9343_RS16340	COG1629	transport
BF9343_RS16340	COG4206	TonB-dependent receptor
BF9343_RS16355	COG4589	Belongs to the CDS family
BF9343_RS16365	COG2304	oxidoreductase activity
BF9343_RS16375	COG0351	phosphomethylpyrimidine kinase
BF9343_RS16385	COG1139	Iron-sulfur cluster binding protein
BF9343_RS16390	COG0247	lactate metabolic process
BF9343_RS16395	COG0602	queuosine metabolic process
BF9343_RS16405	COG2832	Protein of unknown function (DUF454)
BF9343_RS16410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BF9343_RS16425	COG3142	Participates in the control of copper homeostasis
BF9343_RS16430	COG1418	mRNA catabolic process
BF9343_RS16450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BF9343_RS16465	COG4771	TonB-dependent receptor
BF9343_RS16495	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BF9343_RS16605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF9343_RS16605	COG0517	IMP dehydrogenase activity
BF9343_RS16605	COG0617	tRNA 3'-terminal CCA addition
BF9343_RS16630	COG0612	Peptidase, M16
BF9343_RS16640	COG1278	Cold shock
BF9343_RS16665	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS16675	COG0463	Glycosyl transferase, family 2
BF9343_RS16675	COG1216	Glycosyl transferase, family 2
BF9343_RS16680	COG1216	Glycosyl transferase, family 2
BF9343_RS16710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS16755	COG0776	regulation of translation
BF9343_RS16760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BF9343_RS16790	COG0632	four-way junction helicase activity
BF9343_RS16795	COG0673	inositol 2-dehydrogenase activity
BF9343_RS16800	COG1272	protein, Hemolysin III
BF9343_RS16805	COG1328	CTP reductase activity
BF9343_RS16815	COG2814	Major facilitator Superfamily
BF9343_RS16820	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BF9343_RS16825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF9343_RS16835	COG0750	zinc metalloprotease
BF9343_RS16840	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BF9343_RS16850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BF9343_RS16855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BF9343_RS16865	COG1214	PFAM Peptidase M22, glycoprotease
BF9343_RS16880	COG0194	GDP metabolic process
BF9343_RS16885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BF9343_RS16890	COG1408	metallophosphoesterase
BF9343_RS16895	COG1575	Belongs to the MenA family. Type 1 subfamily
BF9343_RS16900	COG1088	dTDP-glucose 4,6-dehydratase activity
BF9343_RS16905	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BF9343_RS16915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BF9343_RS16925	COG2204	response regulator
BF9343_RS16930	COG0488	(ABC) transporter
BF9343_RS17000	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BF9343_RS17010	COG1522	sequence-specific DNA binding
BF9343_RS17035	COG0811	peptide transport
BF9343_RS17045	COG0084	hydrolase, TatD family'
BF9343_RS17060	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BF9343_RS17065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BF9343_RS17070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BF9343_RS17075	COG0205	6-phosphofructokinase activity
BF9343_RS17095	COG0372	Belongs to the citrate synthase family
BF9343_RS17100	COG0538	isocitrate dehydrogenase activity
BF9343_RS17110	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BF9343_RS17120	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BF9343_RS17145	COG0129	dihydroxy-acid dehydratase activity
BF9343_RS17170	COG2885	chlorophyll binding
BF9343_RS17190	COG3681	Belongs to the UPF0597 family
BF9343_RS17220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BF9343_RS17230	COG0702	epimerase
BF9343_RS17235	COG4771	TonB-dependent receptor
BF9343_RS17250	COG0702	epimerase
BF9343_RS17255	COG4206	TonB-dependent receptor
BF9343_RS17255	COG1629	transport
BF9343_RS17260	COG3291	Pkd domain containing protein
BF9343_RS17260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS17270	COG4771	TonB-dependent receptor
BF9343_RS17285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BF9343_RS17325	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF9343_RS17325	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF9343_RS17330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BF9343_RS17365	COG0534	Mate efflux family protein
BF9343_RS17370	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BF9343_RS17375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BF9343_RS17380	COG0166	Belongs to the GPI family
BF9343_RS17390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF9343_RS17400	COG2502	aspartate--ammonia ligase
BF9343_RS17405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BF9343_RS17420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS17440	COG0860	N-Acetylmuramoyl-L-alanine amidase
BF9343_RS17450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BF9343_RS17465	COG1640	4-alpha-glucanotransferase
BF9343_RS17475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BF9343_RS17480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS17505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BF9343_RS17510	COG1022	Amp-dependent synthetase and ligase
BF9343_RS17520	COG0359	binds to the 23S rRNA
BF9343_RS17525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BF9343_RS17530	COG0360	Binds together with S18 to 16S ribosomal RNA
BF9343_RS17550	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BF9343_RS17560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BF9343_RS17580	COG4771	TonB-dependent receptor
BF9343_RS17595	COG2431	L-lysine efflux transmembrane transporter activity
BF9343_RS17610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS17640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BF9343_RS17645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BF9343_RS17650	COG0386	Belongs to the glutathione peroxidase family
BF9343_RS17670	COG3275	phosphorelay sensor kinase activity
BF9343_RS17675	COG3279	Response regulator of the LytR AlgR family
BF9343_RS17695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BF9343_RS17710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BF9343_RS17720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BF9343_RS17725	COG0658	competence protein
BF9343_RS17730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BF9343_RS17735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BF9343_RS17745	COG0009	L-threonylcarbamoyladenylate synthase
BF9343_RS17770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BF9343_RS17775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BF9343_RS17785	COG1216	Glycosyl transferase, family 2
BF9343_RS17795	COG1215	transferase activity, transferring glycosyl groups
BF9343_RS17835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BF9343_RS17840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BF9343_RS17875	COG2818	Glycosylase
BF9343_RS17880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BF9343_RS17880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BF9343_RS17885	COG0514	ATP-dependent DNA helicase (RecQ)
BF9343_RS17895	COG2271	Major facilitator Superfamily
BF9343_RS17910	COG0702	epimerase
BF9343_RS17915	COG4771	TonB-dependent receptor
BF9343_RS17920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF9343_RS17925	COG2186	Transcriptional regulator
BF9343_RS17935	COG0436	Aminotransferase
BF9343_RS17940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BF9343_RS17955	COG0358	DNA primase activity
BF9343_RS17960	COG3119	arylsulfatase activity
BF9343_RS17975	COG4206	TonB-dependent receptor
BF9343_RS17975	COG1629	transport
BF9343_RS17990	COG0302	gtp cyclohydrolase
BF9343_RS18000	COG0149	triose-phosphate isomerase activity
BF9343_RS18015	COG0739	heme binding
BF9343_RS18020	COG0105	UTP biosynthetic process
BF9343_RS18025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BF9343_RS18030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BF9343_RS18050	COG0811	peptide transport
BF9343_RS18060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BF9343_RS18110	COG1629	transport
BF9343_RS18145	COG0039	L-malate dehydrogenase activity
BF9343_RS18175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BF9343_RS18190	COG4948	Mandelate Racemase Muconate Lactonizing
BF9343_RS18210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BF9343_RS18215	COG3118	belongs to the thioredoxin family
BF9343_RS18220	COG0489	protein tyrosine kinase activity
BF9343_RS18225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BF9343_RS18235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BF9343_RS18240	COG1722	exodeoxyribonuclease VII activity
BF9343_RS18245	COG1570	exodeoxyribonuclease VII activity
BF9343_RS18255	COG0482	sulfurtransferase activity
BF9343_RS18275	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BF9343_RS18280	COG0179	Fumarylacetoacetate (FAA) hydrolase
BF9343_RS18285	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BF9343_RS18295	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BF9343_RS18300	COG0052	Belongs to the universal ribosomal protein uS2 family
BF9343_RS18305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BF9343_RS18310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BF9343_RS18320	COG0017	Asparaginyl-tRNA synthetase
BF9343_RS18325	COG1187	pseudouridine synthase activity
BF9343_RS18355	COG0110	maltose O-acetyltransferase activity
BF9343_RS18360	COG3022	response to hydroperoxide
BF9343_RS18365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS18420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BF9343_RS18455	COG1442	glycosyl transferase family 8
BF9343_RS18455	COG1216	Glycosyl transferase, family 2
BF9343_RS18480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BF9343_RS18510	COG0297	glycogen (starch) synthase activity
BF9343_RS18645	COG1918	ferrous iron import across plasma membrane
BF9343_RS18645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BF9343_RS18650	COG2382	esterase
BF9343_RS18650	COG3507	Belongs to the glycosyl hydrolase 43 family
BF9343_RS18650	COG3693	PFAM glycoside hydrolase, family 10
BF9343_RS18655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BF9343_RS18660	COG0436	Aminotransferase
BF9343_RS18665	COG0546	phosphoglycolate phosphatase activity
BF9343_RS18670	COG0351	phosphomethylpyrimidine kinase
BF9343_RS18675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BF9343_RS18680	COG2217	Heavy metal translocating P-type atpase
BF9343_RS18695	COG1475	DNA binding
BF9343_RS18780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BF9343_RS18795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BF9343_RS18810	COG0516	GMP reductase activity
BF9343_RS18810	COG0517	IMP dehydrogenase activity
BF9343_RS18815	COG0514	ATP-dependent DNA helicase (RecQ)
BF9343_RS18820	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BF9343_RS18835	COG0724	RNA recognition motif
BF9343_RS18845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BF9343_RS18850	COG1127	ABC transporter
BF9343_RS18855	COG2197	response regulator
BF9343_RS18860	COG1160	GTP binding
BF9343_RS18865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BF9343_RS18870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BF9343_RS18910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BF9343_RS18915	COG0470	DNA polymerase III
BF9343_RS18920	COG1774	PSP1 C-terminal conserved region
BF9343_RS18930	COG0772	Belongs to the SEDS family
BF9343_RS18945	COG1792	Involved in formation and maintenance of cell shape
BF9343_RS18955	COG0138	bifunctional purine biosynthesis protein purh
BF9343_RS18960	COG3590	peptidase
BF9343_RS18965	COG0488	(ABC) transporter
BF9343_RS18990	COG2205	protein histidine kinase activity
BF9343_RS18990	COG0784	Response regulator, receiver
BF9343_RS18995	COG0534	Mate efflux family protein
BF9343_RS19000	COG0612	Peptidase, M16
BF9343_RS19020	COG0564	pseudouridine synthase activity
BF9343_RS19055	COG2312	Erythromycin esterase
BF9343_RS19075	COG1131	(ABC) transporter
BF9343_RS19155	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BF9343_RS19175	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BF9343_RS19190	COG1696	Membrane protein involved in D-alanine export
BF9343_RS19230	COG2986	histidine ammonia-lyase
BF9343_RS19240	COG1228	amidohydrolase
BF9343_RS19250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BF9343_RS19280	COG0203	ribosomal protein L17
BF9343_RS19285	COG0202	RNA polymerase activity
BF9343_RS19290	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BF9343_RS19295	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BF9343_RS19300	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BF9343_RS19305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BF9343_RS19320	COG0200	Binds to the 23S rRNA
BF9343_RS19325	COG1841	ribosomal large subunit assembly
BF9343_RS19330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BF9343_RS19335	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BF9343_RS19340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BF9343_RS19345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BF9343_RS19350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BF9343_RS19355	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BF9343_RS19360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BF9343_RS19365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BF9343_RS19370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BF9343_RS19375	COG0255	Belongs to the universal ribosomal protein uL29 family
BF9343_RS19380	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BF9343_RS19385	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BF9343_RS19390	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BF9343_RS19395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BF9343_RS19400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BF9343_RS19405	COG0089	rRNA binding
BF9343_RS19410	COG0088	Forms part of the polypeptide exit tunnel
BF9343_RS19415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BF9343_RS19420	COG0051	transcription antitermination factor activity, RNA binding
BF9343_RS19425	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BF9343_RS19430	COG0049	tRNA binding
BF9343_RS19435	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BF9343_RS19465	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BF9343_RS19470	COG0085	RNA polymerase activity
BF9343_RS19475	COG0222	ribosome binding
BF9343_RS19480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BF9343_RS19485	COG0081	regulation of translation
BF9343_RS19490	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BF9343_RS19535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BF9343_RS19540	COG4974	Belongs to the 'phage' integrase family
BF9343_RS19545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BF9343_RS19555	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BF9343_RS19565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BF9343_RS19570	COG1480	7TM receptor with intracellular HD hydrolase
BF9343_RS19575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BF9343_RS19585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BF9343_RS19600	COG1027	Aspartate ammonia-lyase
BF9343_RS19605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BF9343_RS19610	COG0252	asparaginase activity
BF9343_RS19645	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BF9343_RS19670	COG3292	Two component regulator propeller
BF9343_RS19670	COG0745	RESPONSE REGULATOR receiver
BF9343_RS19670	COG2205	protein histidine kinase activity
BF9343_RS19700	COG2271	Major facilitator Superfamily
BF9343_RS19710	COG4771	TonB-dependent receptor
BF9343_RS19715	COG0702	epimerase
BF9343_RS19725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BF9343_RS19740	COG4771	TonB-dependent receptor
BF9343_RS19790	COG1484	DNA-dependent DNA replication
BF9343_RS19845	COG2096	Adenosyltransferase
BF9343_RS19895	COG2755	lipolytic protein G-D-S-L family
BF9343_RS19895	COG0657	acetylesterase activity
BF9343_RS19945	COG3279	Response regulator of the LytR AlgR family
BF9343_RS19960	COG4206	TonB-dependent receptor
BF9343_RS19980	COG2197	response regulator
BF9343_RS19995	COG2207	Transcriptional regulator
BF9343_RS19995	COG0662	Cupin 2, conserved barrel domain protein
BF9343_RS20000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BF9343_RS20030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BF9343_RS20080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BF9343_RS20090	COG1185	polyribonucleotide nucleotidyltransferase activity
BF9343_RS20105	COG4771	TonB-dependent receptor
BF9343_RS20130	COG3426	butyrate kinase activity
BF9343_RS20135	COG0280	phosphate acetyltransferase
BF9343_RS20145	COG1619	proteins homologs of microcin C7 resistance protein MccF
BF9343_RS20150	COG2234	aminopeptidase activity
BF9343_RS20155	COG2166	iron-sulfur cluster assembly
BF9343_RS20160	COG3655	Transcriptional regulator
BF9343_RS20170	COG1266	CAAX protease self-immunity
BF9343_RS20175	COG0196	riboflavin kinase activity
BF9343_RS20180	COG1011	Hydrolase
BF9343_RS20185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BF9343_RS20190	COG2205	protein histidine kinase activity
BF9343_RS20190	COG0784	Response regulator, receiver
BF9343_RS20195	COG1773	rubredoxin
BF9343_RS20200	COG1283	sodium-dependent phosphate transmembrane transporter activity
BF9343_RS20210	COG2205	protein histidine kinase activity
BF9343_RS20235	COG0006	proline dipeptidase activity
BF9343_RS20255	COG0509	glycine decarboxylation via glycine cleavage system
BF9343_RS20260	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BF9343_RS20265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BF9343_RS20285	COG0702	epimerase
BF9343_RS20290	COG4771	TonB-dependent receptor
BF9343_RS20305	COG0793	Belongs to the peptidase S41A family
BF9343_RS20310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BF9343_RS20345	COG4771	TonB-dependent receptor
BF9343_RS20350	COG0745	RESPONSE REGULATOR receiver
BF9343_RS20350	COG2205	protein histidine kinase activity
BF9343_RS20350	COG3292	Two component regulator propeller
BF9343_RS20355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BF9343_RS20360	COG1882	Formate acetyltransferase
BF9343_RS20365	COG2814	Major facilitator Superfamily
BF9343_RS20365	COG0477	Major facilitator Superfamily
BF9343_RS20385	COG1040	competence protein
BF9343_RS20390	COG0483	inositol monophosphate 1-phosphatase activity
BF9343_RS20400	COG3345	alpha-galactosidase
BF9343_RS20425	COG3475	LICD family
BF9343_RS20430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BF9343_RS20460	COG1442	glycosyl transferase family 8
BF9343_RS20545	COG0018	arginyl-trna synthetase
BF9343_RS20575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BF9343_RS20580	COG0776	regulation of translation
BF9343_RS20615	COG2207	Transcriptional regulator
BF9343_RS20615	COG1609	Transcriptional regulator
BF9343_RS20630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BF9343_RS20630	COG0674	pyruvate-flavodoxin oxidoreductase activity
BF9343_RS20635	COG1013	pyruvate-flavodoxin oxidoreductase activity
BF9343_RS20645	COG0584	glycerophosphoryl diester phosphodiesterase
BF9343_RS20650	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BF9343_RS20655	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BF9343_RS20660	COG1629	transport
BF9343_RS20670	COG1629	transport
BF9343_RS20685	COG5434	Belongs to the glycosyl hydrolase 28 family
BF9343_RS20710	COG1629	transport
BF9343_RS20720	COG1217	gtp-binding protein TYPA
BF9343_RS20725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BF9343_RS20735	COG0318	PFAM AMP-dependent synthetase and ligase
BF9343_RS20740	COG3850	Histidine kinase
BF9343_RS20740	COG4999	Histidine kinase
BF9343_RS20740	COG3437	response regulator, receiver
BF9343_RS20740	COG2205	protein histidine kinase activity
BF9343_RS20760	COG3119	arylsulfatase activity
BF9343_RS20785	COG4591	ABC-type transport system involved in lipoprotein release permease component
BF9343_RS20790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BF9343_RS20805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BF9343_RS20810	COG4974	Belongs to the 'phage' integrase family
BF9343_RS20820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BF9343_RS20825	COG0606	chelatase, subunit chli
BF9343_RS20845	COG3292	Two component regulator propeller
BF9343_RS20845	COG0745	RESPONSE REGULATOR receiver
BF9343_RS20845	COG2205	protein histidine kinase activity
BF9343_RS20895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF9343_RS20895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BF9343_RS20905	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS20930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BF9343_RS20935	COG0438	transferase activity, transferring glycosyl groups
BF9343_RS20945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BF9343_RS20950	COG0545	Peptidyl-prolyl cis-trans isomerase
BF9343_RS20955	COG0545	Peptidyl-prolyl cis-trans isomerase
BF9343_RS20960	COG1522	sequence-specific DNA binding
BF9343_RS20980	COG3275	phosphorelay sensor kinase activity
BF9343_RS21055	COG1629	transport
BF9343_RS21055	COG4206	TonB-dependent receptor
BF9343_RS21065	COG2814	Major facilitator Superfamily
BF9343_RS21070	COG0745	RESPONSE REGULATOR receiver
BF9343_RS21070	COG2205	protein histidine kinase activity
BF9343_RS21070	COG3292	Two component regulator propeller
BF9343_RS21075	COG1621	beta-fructofuranosidase activity
BF9343_RS21110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BF9343_RS21115	COG0793	Belongs to the peptidase S41A family
BF9343_RS21115	COG3409	Peptidoglycan-binding domain 1 protein
BF9343_RS21135	COG1053	succinate dehydrogenase
BF9343_RS21140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BF9343_RS21155	COG4771	TonB-dependent receptor
BF9343_RS21180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BF9343_RS21180	COG0758	DNA mediated transformation
BF9343_RS21190	COG0826	peptidase U32
BF9343_RS21200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BF9343_RS21215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BF9343_RS21220	COG0557	exoribonuclease II activity
BF9343_RS21245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BF9343_RS21260	COG0012	GTP binding
BF9343_RS21265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BF9343_RS21270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BF9343_RS21280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BF9343_RS21290	COG0495	leucyl-tRNA aminoacylation
BF9343_RS21295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BF9343_RS21305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BF9343_RS21480	COG0659	secondary active sulfate transmembrane transporter activity
BF9343_RS21500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BF9343_RS21590	COG0732	type I restriction modification DNA specificity domain