locus-tag	class	description
BUN20_RS00025	COG1846	Transcriptional regulator
BUN20_RS00105	COG1435	thymidine kinase activity
BUN20_RS00115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUN20_RS00130	COG2095	MarC family integral membrane protein
BUN20_RS00140	COG1629	transport
BUN20_RS00150	COG4771	TonB-dependent receptor
BUN20_RS00165	COG4974	Belongs to the 'phage' integrase family
BUN20_RS00175	COG4771	TonB-dependent receptor
BUN20_RS00180	COG0702	epimerase
BUN20_RS00185	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUN20_RS00205	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BUN20_RS00205	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BUN20_RS00220	COG0531	amino acid
BUN20_RS00230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUN20_RS00235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS00240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS00280	COG1162	GTPase activity
BUN20_RS00285	COG0233	cytoplasmic translational termination
BUN20_RS00305	COG0443	Heat shock 70 kDa protein
BUN20_RS00315	COG0528	UMP kinase activity
BUN20_RS00320	COG0534	Mate efflux family protein
BUN20_RS00345	COG0792	nuclease activity
BUN20_RS00365	COG1183	phosphatidylcholine synthase activity
BUN20_RS00370	COG0688	phosphatidylethanolamine metabolic process
BUN20_RS00380	COG3118	belongs to the thioredoxin family
BUN20_RS00400	COG1136	(ABC) transporter
BUN20_RS00400	COG0577	efflux transmembrane transporter activity
BUN20_RS00450	COG2205	protein histidine kinase activity
BUN20_RS00480	COG0714	Associated with various cellular activities
BUN20_RS00495	COG0802	atpase or kinase
BUN20_RS00500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUN20_RS00510	COG2234	aminopeptidase activity
BUN20_RS00540	COG1629	transport
BUN20_RS00560	COG3250	beta-galactosidase activity
BUN20_RS00575	COG2205	protein histidine kinase activity
BUN20_RS00575	COG0784	Response regulator, receiver
BUN20_RS00590	COG1566	PFAM secretion protein HlyD family protein
BUN20_RS00610	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BUN20_RS00625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN20_RS00630	COG0742	ribosomal rna small subunit methyltransferase
BUN20_RS00655	COG4771	TonB-dependent receptor
BUN20_RS00665	COG3537	Alpha-1,2-mannosidase
BUN20_RS00680	COG3537	Alpha-1,2-mannosidase
BUN20_RS00685	COG2814	Major facilitator Superfamily
BUN20_RS00720	COG0739	heme binding
BUN20_RS00730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUN20_RS00735	COG1388	LysM domain
BUN20_RS00735	COG3942	CHAP domain
BUN20_RS00745	COG1475	DNA binding
BUN20_RS00750	COG1192	Involved in chromosome partitioning
BUN20_RS00760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BUN20_RS00765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BUN20_RS00780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUN20_RS00785	COG0799	negative regulation of ribosome biogenesis
BUN20_RS00800	COG2239	Acts as a magnesium transporter
BUN20_RS00805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BUN20_RS00815	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUN20_RS00875	COG0668	transmembrane transport
BUN20_RS00880	COG0662	Cupin 2, conserved barrel domain protein
BUN20_RS00880	COG2207	Transcriptional regulator
BUN20_RS00920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS00925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BUN20_RS00945	COG0562	UDP-galactopyranose mutase
BUN20_RS00970	COG0438	transferase activity, transferring glycosyl groups
BUN20_RS00975	COG0297	glycogen (starch) synthase activity
BUN20_RS00975	COG0438	transferase activity, transferring glycosyl groups
BUN20_RS00990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUN20_RS01000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUN20_RS01015	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS01020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN20_RS01040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS01055	COG1373	ATPase (AAA superfamily
BUN20_RS01060	COG0667	Aldo Keto reductase
BUN20_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
BUN20_RS01070	COG4771	TonB-dependent receptor
BUN20_RS01075	COG0702	epimerase
BUN20_RS01115	COG5012	cobalamin binding
BUN20_RS01125	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BUN20_RS01130	COG4124	Belongs to the glycosyl hydrolase 26 family
BUN20_RS01135	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BUN20_RS01140	COG2211	Major facilitator Superfamily
BUN20_RS01145	COG2942	2-epimerase
BUN20_RS01180	COG4412	M6 family metalloprotease domain protein
BUN20_RS01180	COG1404	Belongs to the peptidase S8 family
BUN20_RS01190	COG2205	protein histidine kinase activity
BUN20_RS01190	COG2202	Pas domain
BUN20_RS01200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BUN20_RS01205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BUN20_RS01210	COG0713	ATP synthesis coupled electron transport
BUN20_RS01215	COG0839	Belongs to the complex I subunit 6 family
BUN20_RS01225	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BUN20_RS01230	COG0649	NAD binding
BUN20_RS01230	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BUN20_RS01235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BUN20_RS01240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BUN20_RS01250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUN20_RS01255	COG0569	domain protein
BUN20_RS01260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BUN20_RS01265	COG1073	alpha beta
BUN20_RS01280	COG0546	phosphoglycolate phosphatase activity
BUN20_RS01285	COG3119	arylsulfatase activity
BUN20_RS01300	COG3119	arylsulfatase activity
BUN20_RS01310	COG1629	transport
BUN20_RS01315	COG0745	RESPONSE REGULATOR receiver
BUN20_RS01315	COG3292	Two component regulator propeller
BUN20_RS01315	COG2205	protein histidine kinase activity
BUN20_RS01320	COG2271	Major facilitator Superfamily
BUN20_RS01365	COG0805	protein transport
BUN20_RS01370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUN20_RS01375	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUN20_RS01395	COG4585	Histidine kinase
BUN20_RS01410	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BUN20_RS01420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BUN20_RS01425	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BUN20_RS01425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BUN20_RS01430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BUN20_RS01435	COG1078	dGTPase activity
BUN20_RS01440	COG0284	orotidine-5'-phosphate decarboxylase activity
BUN20_RS01445	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BUN20_RS01450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BUN20_RS01460	COG1704	LemA family
BUN20_RS01475	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUN20_RS01480	COG2226	methyltransferase
BUN20_RS01485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BUN20_RS01490	COG1702	phosphate starvation-inducible protein PhoH
BUN20_RS01500	COG2268	Band 7 protein
BUN20_RS01510	COG5434	Belongs to the glycosyl hydrolase 28 family
BUN20_RS01520	COG0101	tRNA pseudouridine synthase activity
BUN20_RS01540	COG3250	beta-galactosidase activity
BUN20_RS01545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN20_RS01570	COG0457	Tetratricopeptide repeat
BUN20_RS01575	COG2814	Major facilitator Superfamily
BUN20_RS01600	COG0702	epimerase
BUN20_RS01605	COG1629	transport
BUN20_RS01605	COG4206	TonB-dependent receptor
BUN20_RS01615	COG4771	TonB-dependent receptor
BUN20_RS01625	COG4206	TonB-dependent receptor
BUN20_RS01625	COG1629	transport
BUN20_RS01640	COG4206	TonB-dependent receptor
BUN20_RS01640	COG1629	transport
BUN20_RS01655	COG0673	inositol 2-dehydrogenase activity
BUN20_RS01695	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUN20_RS01700	COG0793	Belongs to the peptidase S41A family
BUN20_RS01705	COG2131	deaminase
BUN20_RS01715	COG0339	signal peptide processing
BUN20_RS01725	COG1970	mechanosensitive ion channel activity
BUN20_RS01730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BUN20_RS01730	COG0519	Catalyzes the synthesis of GMP from XMP
BUN20_RS01740	COG4206	TonB-dependent receptor
BUN20_RS01740	COG1629	transport
BUN20_RS01745	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BUN20_RS01755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUN20_RS01765	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BUN20_RS01790	COG1242	4 iron, 4 sulfur cluster binding
BUN20_RS01800	COG0363	glucosamine-6-phosphate deaminase activity
BUN20_RS01810	COG0009	L-threonylcarbamoyladenylate synthase
BUN20_RS01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUN20_RS01825	COG0561	phosphatase activity
BUN20_RS01830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUN20_RS01835	COG0626	cystathionine gamma-synthase activity
BUN20_RS01890	COG0297	glycogen (starch) synthase activity
BUN20_RS01895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BUN20_RS01900	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BUN20_RS01905	COG0543	2 iron, 2 sulfur cluster binding
BUN20_RS01915	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BUN20_RS01925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BUN20_RS01930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BUN20_RS01945	COG0546	phosphoglycolate phosphatase activity
BUN20_RS01950	COG0791	NLP P60 protein
BUN20_RS01955	COG1131	(ABC) transporter
BUN20_RS01965	COG0612	Peptidase, M16
BUN20_RS01970	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BUN20_RS01975	COG1597	lipid kinase activity
BUN20_RS01990	COG1136	(ABC) transporter
BUN20_RS02010	COG2211	Major facilitator Superfamily
BUN20_RS02095	COG4104	PAAR repeat-containing protein
BUN20_RS02095	COG3209	COG3209 Rhs family protein
BUN20_RS02175	COG0542	response to heat
BUN20_RS02245	COG3209	COG3209 Rhs family protein
BUN20_RS02355	COG0587	DNA-directed DNA polymerase activity
BUN20_RS02370	COG0587	DNA-directed DNA polymerase activity
BUN20_RS02560	COG0740	serine-type endopeptidase activity
BUN20_RS02945	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUN20_RS02980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUN20_RS02995	COG1674	ftsk spoiiie
BUN20_RS03005	COG0492	ferredoxin-NADP+ reductase activity
BUN20_RS03010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS03050	COG1595	DNA-templated transcription, initiation
BUN20_RS03065	COG3956	TIGRFAM MazG family protein
BUN20_RS03075	COG0525	valine-tRNA ligase activity
BUN20_RS03080	COG0784	Response regulator, receiver
BUN20_RS03080	COG2205	protein histidine kinase activity
BUN20_RS03080	COG2198	Histidine kinase
BUN20_RS03115	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BUN20_RS03130	COG4771	TonB-dependent receptor
BUN20_RS03135	COG0702	epimerase
BUN20_RS03140	COG3119	arylsulfatase activity
BUN20_RS03145	COG3119	arylsulfatase activity
BUN20_RS03165	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
BUN20_RS03175	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BUN20_RS03195	COG1253	flavin adenine dinucleotide binding
BUN20_RS03205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BUN20_RS03215	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BUN20_RS03255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUN20_RS03285	COG2244	polysaccharide biosynthetic process
BUN20_RS03300	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BUN20_RS03315	COG2843	Capsule synthesis protein
BUN20_RS03325	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BUN20_RS03345	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS03350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS03355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN20_RS03370	COG4771	TonB-dependent receptor
BUN20_RS03380	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BUN20_RS03385	COG0563	adenylate kinase activity
BUN20_RS03390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BUN20_RS03395	COG1496	oxidoreductase activity
BUN20_RS03415	COG2706	6-phosphogluconolactonase activity
BUN20_RS03435	COG2207	Transcriptional regulator
BUN20_RS03455	COG1288	antiporter activity
BUN20_RS03490	COG0454	-acetyltransferase
BUN20_RS03495	COG0564	pseudouridine synthase activity
BUN20_RS03510	COG1501	Belongs to the glycosyl hydrolase 31 family
BUN20_RS03540	COG3011	Protein conserved in bacteria
BUN20_RS03555	COG0148	phosphopyruvate hydratase activity
BUN20_RS03565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUN20_RS03570	COG1082	Xylose isomerase domain protein TIM barrel
BUN20_RS03600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUN20_RS03605	COG0193	aminoacyl-tRNA hydrolase activity
BUN20_RS03610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BUN20_RS03620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUN20_RS03625	COG1862	Preprotein translocase
BUN20_RS03635	COG0237	dephospho-CoA kinase activity
BUN20_RS03650	COG0542	response to heat
BUN20_RS03660	COG0583	DNA-binding transcription factor activity
BUN20_RS03665	COG2855	membrane
BUN20_RS03680	COG1595	DNA-templated transcription, initiation
BUN20_RS03695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BUN20_RS03715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUN20_RS03735	COG0443	Heat shock 70 kDa protein
BUN20_RS03745	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BUN20_RS03750	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BUN20_RS03755	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUN20_RS03775	COG1501	Belongs to the glycosyl hydrolase 31 family
BUN20_RS03795	COG4206	TonB-dependent receptor
BUN20_RS03795	COG1629	transport
BUN20_RS03805	COG1408	metallophosphoesterase
BUN20_RS03815	COG3634	alkyl hydroperoxide reductase activity
BUN20_RS03855	COG1760	l-serine dehydratase
BUN20_RS03860	COG0598	Magnesium transport protein CorA
BUN20_RS03865	COG1193	negative regulation of DNA recombination
BUN20_RS03875	COG0784	Response regulator, receiver
BUN20_RS03875	COG5002	protein histidine kinase activity
BUN20_RS03880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BUN20_RS03885	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUN20_RS03890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUN20_RS03895	COG3189	MarR family transcriptional regulator
BUN20_RS03900	COG2885	chlorophyll binding
BUN20_RS03910	COG2217	Heavy metal translocating P-type atpase
BUN20_RS03915	COG2855	membrane
BUN20_RS03935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUN20_RS03935	COG2207	Transcriptional regulator
BUN20_RS04015	COG4651	solute:proton antiporter activity
BUN20_RS04015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUN20_RS04020	COG1280	lysine exporter protein (LysE YggA)
BUN20_RS04035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BUN20_RS04040	COG0561	phosphatase activity
BUN20_RS04045	COG1169	isochorismate synthase
BUN20_RS04050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BUN20_RS04060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BUN20_RS04065	COG4948	Mandelate Racemase Muconate Lactonizing
BUN20_RS04080	COG1082	Xylose isomerase domain protein TIM barrel
BUN20_RS04095	COG4771	TonB-dependent receptor
BUN20_RS04125	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BUN20_RS04130	COG0783	Belongs to the Dps family
BUN20_RS04155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BUN20_RS04175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BUN20_RS04175	COG2755	lipolytic protein G-D-S-L family
BUN20_RS04200	COG1253	flavin adenine dinucleotide binding
BUN20_RS04205	COG0501	Belongs to the peptidase M48B family
BUN20_RS04235	COG2873	o-acetylhomoserine
BUN20_RS04255	COG1757	Na H antiporter
BUN20_RS04270	COG2814	Major facilitator Superfamily
BUN20_RS04275	COG4953	penicillin-binding protein 1C
BUN20_RS04280	COG2373	Large extracellular alpha-helical protein
BUN20_RS04290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUN20_RS04290	COG1918	ferrous iron import across plasma membrane
BUN20_RS04365	COG1086	Polysaccharide biosynthesis protein
BUN20_RS04370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS04385	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS04395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUN20_RS04425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BUN20_RS04430	COG0463	Glycosyl transferase, family 2
BUN20_RS04430	COG1216	Glycosyl transferase, family 2
BUN20_RS04440	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS04460	COG0471	metal ion transport
BUN20_RS04460	COG0490	domain, Protein
BUN20_RS04475	COG0346	lactoylglutathione lyase activity
BUN20_RS04490	COG0259	pyridoxamine-phosphate oxidase activity
BUN20_RS04495	COG1741	Belongs to the pirin family
BUN20_RS04510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN20_RS04535	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BUN20_RS04545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BUN20_RS04560	COG1595	DNA-templated transcription, initiation
BUN20_RS04585	COG0686	Belongs to the AlaDH PNT family
BUN20_RS04605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUN20_RS04620	COG1629	transport
BUN20_RS04635	COG3345	alpha-galactosidase
BUN20_RS04665	COG0488	(ABC) transporter
BUN20_RS04670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUN20_RS04675	COG3059	membrane
BUN20_RS04680	COG2207	Transcriptional regulator
BUN20_RS04680	COG0662	Cupin 2, conserved barrel domain protein
BUN20_RS04685	COG0295	cytidine deaminase activity
BUN20_RS04690	COG1705	Flagellar rod assembly protein muramidase FlgJ
BUN20_RS04690	COG1388	LysM domain
BUN20_RS04705	COG0577	efflux transmembrane transporter activity
BUN20_RS04715	COG0577	efflux transmembrane transporter activity
BUN20_RS04725	COG0577	efflux transmembrane transporter activity
BUN20_RS04735	COG1136	(ABC) transporter
BUN20_RS04735	COG0577	efflux transmembrane transporter activity
BUN20_RS04745	COG0662	Cupin 2, conserved barrel domain protein
BUN20_RS04745	COG2207	Transcriptional regulator
BUN20_RS04760	COG1136	(ABC) transporter
BUN20_RS04765	COG0577	efflux transmembrane transporter activity
BUN20_RS04775	COG1136	(ABC) transporter
BUN20_RS04795	COG0784	Response regulator, receiver
BUN20_RS04795	COG2205	protein histidine kinase activity
BUN20_RS04805	COG2204	response regulator
BUN20_RS04810	COG4191	Histidine kinase
BUN20_RS04830	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BUN20_RS04860	COG0582	viral genome integration into host DNA
BUN20_RS04945	COG1088	dTDP-glucose 4,6-dehydratase activity
BUN20_RS04955	COG0656	L-ascorbic acid biosynthetic process
BUN20_RS04975	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS04995	COG1216	Glycosyl transferase, family 2
BUN20_RS05005	COG0438	transferase activity, transferring glycosyl groups
BUN20_RS05015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS05020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN20_RS05025	COG1530	ribonuclease E activity
BUN20_RS05040	COG3119	arylsulfatase activity
BUN20_RS05045	COG0629	single-stranded DNA binding
BUN20_RS05110	COG4206	TonB-dependent receptor
BUN20_RS05140	COG0745	RESPONSE REGULATOR receiver
BUN20_RS05165	COG0488	(ABC) transporter
BUN20_RS05180	COG5492	domain, Protein
BUN20_RS05190	COG0436	Aminotransferase
BUN20_RS05195	COG4591	ABC-type transport system involved in lipoprotein release permease component
BUN20_RS05200	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS05205	COG0628	permease
BUN20_RS05225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS05235	COG1136	(ABC) transporter
BUN20_RS05235	COG0577	efflux transmembrane transporter activity
BUN20_RS05240	COG0577	efflux transmembrane transporter activity
BUN20_RS05240	COG1136	(ABC) transporter
BUN20_RS05245	COG1252	NADH dehydrogenase
BUN20_RS05275	COG4771	TonB-dependent receptor
BUN20_RS05285	COG1620	l-lactate permease
BUN20_RS05290	COG2885	chlorophyll binding
BUN20_RS05290	COG3047	cAMP biosynthetic process
BUN20_RS05300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN20_RS05305	COG0439	Biotin carboxylase
BUN20_RS05310	COG0511	ligase activity, forming carbon-carbon bonds
BUN20_RS05320	COG2226	methyltransferase
BUN20_RS05325	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUN20_RS05360	COG0784	Response regulator, receiver
BUN20_RS05360	COG2205	protein histidine kinase activity
BUN20_RS05360	COG2198	Histidine kinase
BUN20_RS05365	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUN20_RS05370	COG0022	dehydrogenase e1 component
BUN20_RS05375	COG0716	FMN binding
BUN20_RS05380	COG2264	protein methyltransferase activity
BUN20_RS05400	COG0590	tRNA wobble adenosine to inosine editing
BUN20_RS05425	COG0673	inositol 2-dehydrogenase activity
BUN20_RS05430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BUN20_RS05480	COG0698	ribose 5-phosphate isomerase
BUN20_RS05485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUN20_RS05490	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUN20_RS05505	COG1482	cell wall glycoprotein biosynthetic process
BUN20_RS05525	COG0513	Belongs to the DEAD box helicase family
BUN20_RS05530	COG4221	oxidoreductase activity
BUN20_RS05550	COG3273	potassium ion transport
BUN20_RS05550	COG0471	metal ion transport
BUN20_RS05555	COG0529	Catalyzes the synthesis of activated sulfate
BUN20_RS05560	COG0175	sulfate reduction
BUN20_RS05580	COG2885	chlorophyll binding
BUN20_RS05600	COG4974	Belongs to the 'phage' integrase family
BUN20_RS05625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BUN20_RS05630	COG0242	peptide deformylase activity
BUN20_RS05645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BUN20_RS05650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BUN20_RS05655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BUN20_RS05660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BUN20_RS05670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUN20_RS05675	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BUN20_RS05680	COG1013	pyruvate-flavodoxin oxidoreductase activity
BUN20_RS05680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BUN20_RS05680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BUN20_RS05680	COG0674	pyruvate-flavodoxin oxidoreductase activity
BUN20_RS05690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUN20_RS05730	COG1940	carbohydrate kinase activity
BUN20_RS05735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BUN20_RS05745	COG2271	Major facilitator Superfamily
BUN20_RS05750	COG2731	YhcH YjgK YiaL family protein
BUN20_RS05755	COG1629	transport
BUN20_RS05760	COG0702	epimerase
BUN20_RS05780	COG1629	transport
BUN20_RS05785	COG0702	epimerase
BUN20_RS05795	COG4771	TonB-dependent receptor
BUN20_RS05800	COG0702	epimerase
BUN20_RS05805	COG0702	epimerase
BUN20_RS05810	COG4206	TonB-dependent receptor
BUN20_RS05810	COG1629	transport
BUN20_RS05815	COG1629	transport
BUN20_RS05815	COG4206	TonB-dependent receptor
BUN20_RS05830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS05850	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS05860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS05865	COG3537	Alpha-1,2-mannosidase
BUN20_RS05870	COG3250	beta-galactosidase activity
BUN20_RS05875	COG4771	TonB-dependent receptor
BUN20_RS05880	COG0702	epimerase
BUN20_RS05895	COG0484	heat shock protein binding
BUN20_RS05900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BUN20_RS05905	COG0488	(ABC) transporter
BUN20_RS05910	COG1595	DNA-templated transcription, initiation
BUN20_RS05965	COG2885	chlorophyll binding
BUN20_RS06080	COG2183	response to ionizing radiation
BUN20_RS06085	COG2205	protein histidine kinase activity
BUN20_RS06085	COG2202	Pas domain
BUN20_RS06090	COG0737	Belongs to the 5'-nucleotidase family
BUN20_RS06095	COG1956	GAF domain-containing protein
BUN20_RS06105	COG4771	TonB-dependent receptor
BUN20_RS06130	COG0534	Mate efflux family protein
BUN20_RS06145	COG4771	TonB-dependent receptor
BUN20_RS06175	COG0534	Mate efflux family protein
BUN20_RS06185	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BUN20_RS06195	COG0318	PFAM AMP-dependent synthetase and ligase
BUN20_RS06200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS06205	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BUN20_RS06245	COG2244	polysaccharide biosynthetic process
BUN20_RS06260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BUN20_RS06275	COG1086	Polysaccharide biosynthesis protein
BUN20_RS06285	COG1091	dTDP-4-dehydrorhamnose reductase activity
BUN20_RS06295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS06320	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BUN20_RS06325	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUN20_RS06330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUN20_RS06335	COG0363	glucosamine-6-phosphate deaminase activity
BUN20_RS06375	COG1742	UPF0060 membrane protein
BUN20_RS06435	COG3279	Response regulator of the LytR AlgR family
BUN20_RS06445	COG0577	efflux transmembrane transporter activity
BUN20_RS06445	COG1136	(ABC) transporter
BUN20_RS06450	COG1136	(ABC) transporter
BUN20_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS06490	COG3831	ATPase activity
BUN20_RS06490	COG4884	unkown
BUN20_RS06505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN20_RS06515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUN20_RS06520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUN20_RS06525	COG3250	beta-galactosidase activity
BUN20_RS06550	COG0501	Belongs to the peptidase M48B family
BUN20_RS06555	COG1704	LemA family
BUN20_RS06560	COG1595	DNA-templated transcription, initiation
BUN20_RS06570	COG1629	transport
BUN20_RS06570	COG4206	TonB-dependent receptor
BUN20_RS06580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN20_RS06585	COG2885	chlorophyll binding
BUN20_RS06585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BUN20_RS06595	COG0697	spore germination
BUN20_RS06630	COG0656	L-ascorbic acid biosynthetic process
BUN20_RS06640	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BUN20_RS06645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN20_RS06650	COG2814	Major facilitator Superfamily
BUN20_RS06655	COG4771	TonB-dependent receptor
BUN20_RS06685	COG4771	TonB-dependent receptor
BUN20_RS06730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN20_RS06735	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUN20_RS06790	COG0488	(ABC) transporter
BUN20_RS06810	COG3437	response regulator, receiver
BUN20_RS06810	COG4999	Histidine kinase
BUN20_RS06810	COG2205	protein histidine kinase activity
BUN20_RS06810	COG3850	Histidine kinase
BUN20_RS06825	COG1442	glycosyl transferase family 8
BUN20_RS06825	COG1216	Glycosyl transferase, family 2
BUN20_RS06845	COG2244	polysaccharide biosynthetic process
BUN20_RS06850	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS06870	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS06900	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BUN20_RS06905	COG1805	sodium ion transport
BUN20_RS06910	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BUN20_RS06935	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BUN20_RS06940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN20_RS06950	COG0545	Peptidyl-prolyl cis-trans isomerase
BUN20_RS06955	COG1739	Uncharacterized protein family UPF0029
BUN20_RS06965	COG0778	Nitroreductase
BUN20_RS06970	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BUN20_RS06970	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BUN20_RS06975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUN20_RS07005	COG2217	Heavy metal translocating P-type atpase
BUN20_RS07015	COG0321	lipoyl(octanoyl) transferase activity
BUN20_RS07035	COG3852	Histidine kinase
BUN20_RS07040	COG2204	response regulator
BUN20_RS07055	COG1136	(ABC) transporter
BUN20_RS07070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN20_RS07080	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUN20_RS07090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BUN20_RS07105	COG1678	Uncharacterized ACR, COG1678
BUN20_RS07150	COG4771	TonB-dependent receptor
BUN20_RS07160	COG3119	arylsulfatase activity
BUN20_RS07165	COG3250	beta-galactosidase activity
BUN20_RS07180	COG0681	Belongs to the peptidase S26 family
BUN20_RS07215	COG3969	phosphoadenosine phosphosulfate
BUN20_RS07220	COG1475	DNA binding
BUN20_RS07265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS07270	COG0745	RESPONSE REGULATOR receiver
BUN20_RS07280	COG1074	ATP-dependent DNA helicase activity
BUN20_RS07285	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS07295	COG1629	transport
BUN20_RS07295	COG4206	TonB-dependent receptor
BUN20_RS07470	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BUN20_RS07490	COG1022	Amp-dependent synthetase and ligase
BUN20_RS07495	COG3263	regulation of cellular component size
BUN20_RS07505	COG1151	hydroxylamine reductase activity
BUN20_RS07520	COG2204	response regulator
BUN20_RS07540	COG0577	efflux transmembrane transporter activity
BUN20_RS07540	COG1136	(ABC) transporter
BUN20_RS07550	COG1136	(ABC) transporter
BUN20_RS07560	COG0534	Mate efflux family protein
BUN20_RS07570	COG0167	dihydroorotate dehydrogenase activity
BUN20_RS07575	COG0657	acetylesterase activity
BUN20_RS07575	COG2755	lipolytic protein G-D-S-L family
BUN20_RS07580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BUN20_RS07595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUN20_RS07630	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BUN20_RS07640	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BUN20_RS07650	COG0356	it plays a direct role in the translocation of protons across the membrane
BUN20_RS07655	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUN20_RS07660	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BUN20_RS07665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUN20_RS07670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BUN20_RS07675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BUN20_RS07680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUN20_RS07685	COG3118	belongs to the thioredoxin family
BUN20_RS07705	COG0745	RESPONSE REGULATOR receiver
BUN20_RS07710	COG5002	protein histidine kinase activity
BUN20_RS07745	COG1120	ATPase activity
BUN20_RS07750	COG1091	dTDP-4-dehydrorhamnose reductase activity
BUN20_RS07790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BUN20_RS07795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BUN20_RS07815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUN20_RS07820	COG1064	alcohol dehydrogenase
BUN20_RS07835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUN20_RS07845	COG2202	Pas domain
BUN20_RS07845	COG2205	protein histidine kinase activity
BUN20_RS07850	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BUN20_RS07860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BUN20_RS07875	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BUN20_RS07880	COG0540	Belongs to the ATCase OTCase family
BUN20_RS07895	COG2431	L-lysine efflux transmembrane transporter activity
BUN20_RS07925	COG2837	iron assimilation
BUN20_RS07935	COG1629	transport
BUN20_RS07935	COG4206	TonB-dependent receptor
BUN20_RS07955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BUN20_RS07965	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BUN20_RS07980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BUN20_RS07985	COG2205	protein histidine kinase activity
BUN20_RS08005	COG2135	peptidase activity
BUN20_RS08015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN20_RS08020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN20_RS08045	COG0673	inositol 2-dehydrogenase activity
BUN20_RS08060	COG2223	nitrite transmembrane transporter activity
BUN20_RS08080	COG0671	phosphoesterase, PA-phosphatase related
BUN20_RS08100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BUN20_RS08105	COG0045	succinate-CoA ligase (ADP-forming) activity
BUN20_RS08110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUN20_RS08115	COG0351	phosphomethylpyrimidine kinase
BUN20_RS08125	COG1070	Carbohydrate kinase
BUN20_RS08135	COG0477	Major facilitator Superfamily
BUN20_RS08135	COG2814	Major facilitator Superfamily
BUN20_RS08145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN20_RS08145	COG3153	acetyltransferase
BUN20_RS08150	COG0450	alkyl hydroperoxide reductase
BUN20_RS08155	COG0724	RNA recognition motif
BUN20_RS08160	COG1858	cytochrome C peroxidase
BUN20_RS08165	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN20_RS08190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BUN20_RS08200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BUN20_RS08215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUN20_RS08265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUN20_RS08275	COG1904	glucuronate isomerase
BUN20_RS08305	COG0513	Belongs to the DEAD box helicase family
BUN20_RS08335	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BUN20_RS08340	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUN20_RS08400	COG2204	response regulator
BUN20_RS08450	COG0577	efflux transmembrane transporter activity
BUN20_RS08450	COG1136	(ABC) transporter
BUN20_RS08460	COG0156	8-amino-7-oxononanoate synthase activity
BUN20_RS08465	COG1597	lipid kinase activity
BUN20_RS08470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BUN20_RS08495	COG1132	(ABC) transporter
BUN20_RS08520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUN20_RS08550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUN20_RS08570	COG0543	2 iron, 2 sulfur cluster binding
BUN20_RS08575	COG0167	dihydroorotate dehydrogenase activity
BUN20_RS08580	COG0336	Belongs to the RNA methyltransferase TrmD family
BUN20_RS08585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BUN20_RS08590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BUN20_RS08615	COG0326	Molecular chaperone. Has ATPase activity
BUN20_RS08620	COG0542	response to heat
BUN20_RS08665	COG2304	oxidoreductase activity
BUN20_RS08680	COG0714	Associated with various cellular activities
BUN20_RS08685	COG1652	LysM domain
BUN20_RS08695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUN20_RS08700	COG0552	protein localization to endoplasmic reticulum
BUN20_RS08710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUN20_RS08715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BUN20_RS08720	COG1546	Belongs to the CinA family
BUN20_RS08720	COG1058	Belongs to the CinA family
BUN20_RS08725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BUN20_RS08740	COG0442	prolyl-tRNA aminoacylation
BUN20_RS08755	COG0793	Belongs to the peptidase S41A family
BUN20_RS08755	COG4946	Tricorn protease homolog
BUN20_RS08775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BUN20_RS08790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BUN20_RS08800	COG1492	cobalamin metabolic process
BUN20_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS08865	COG0784	Response regulator, receiver
BUN20_RS08865	COG2198	Histidine kinase
BUN20_RS08865	COG5002	protein histidine kinase activity
BUN20_RS08870	COG2096	Adenosyltransferase
BUN20_RS08875	COG1797	cobyrinic acid a,c-diamide synthase activity
BUN20_RS08890	COG2966	Psort location CytoplasmicMembrane, score
BUN20_RS08905	COG4771	TonB-dependent receptor
BUN20_RS08915	COG4774	siderophore transport
BUN20_RS08940	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BUN20_RS09000	COG0305	Participates in initiation and elongation during chromosome replication
BUN20_RS09010	COG3023	N-Acetylmuramoyl-L-alanine amidase
BUN20_RS09075	COG0352	thiamine-phosphate diphosphorylase activity
BUN20_RS09080	COG2022	thiamine diphosphate biosynthetic process
BUN20_RS09085	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BUN20_RS09100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUN20_RS09105	COG0352	thiamine-phosphate diphosphorylase activity
BUN20_RS09120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BUN20_RS09120	COG0574	Belongs to the PEP-utilizing enzyme family
BUN20_RS09125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUN20_RS09130	COG0564	pseudouridine synthase activity
BUN20_RS09145	COG0024	Methionine aminopeptidase
BUN20_RS09170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BUN20_RS09180	COG0481	GTPase activity
BUN20_RS09200	COG0708	Exodeoxyribonuclease III
BUN20_RS09205	COG1914	H( )-stimulated, divalent metal cation uptake system
BUN20_RS09220	COG0217	transcriptional regulatory protein
BUN20_RS09225	COG0072	phenylalanine-tRNA ligase activity
BUN20_RS09225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUN20_RS09230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN20_RS09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS09245	COG1216	Glycosyl transferase, family 2
BUN20_RS09255	COG1216	Glycosyl transferase, family 2
BUN20_RS09260	COG1216	Glycosyl transferase, family 2
BUN20_RS09280	COG0028	Belongs to the TPP enzyme family
BUN20_RS09285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS09295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUN20_RS09305	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BUN20_RS09335	COG0305	Participates in initiation and elongation during chromosome replication
BUN20_RS09340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BUN20_RS09355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUN20_RS09360	COG4657	Part of a membrane complex involved in electron transport
BUN20_RS09365	COG4660	Part of a membrane complex involved in electron transport
BUN20_RS09370	COG4659	FMN binding
BUN20_RS09375	COG4658	electron transport chain
BUN20_RS09380	COG4656	Part of a membrane complex involved in electron transport
BUN20_RS09405	COG0504	CTP synthase activity
BUN20_RS09415	COG0534	Mate efflux family protein
BUN20_RS09420	COG1506	peptidase
BUN20_RS09420	COG0823	Involved in the tonB-independent uptake of proteins
BUN20_RS09435	COG0110	maltose O-acetyltransferase activity
BUN20_RS09445	COG1695	Transcriptional regulator
BUN20_RS09460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUN20_RS09470	COG3942	CHAP domain
BUN20_RS09470	COG1388	LysM domain
BUN20_RS09500	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BUN20_RS09505	COG0556	nucleotide-excision repair
BUN20_RS09515	COG2949	membrane
BUN20_RS09530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BUN20_RS09545	COG2198	Histidine kinase
BUN20_RS09545	COG0784	Response regulator, receiver
BUN20_RS09545	COG2205	protein histidine kinase activity
BUN20_RS09550	COG0842	Transport permease protein
BUN20_RS09555	COG0842	Transport permease protein
BUN20_RS09560	COG1131	(ABC) transporter
BUN20_RS09595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN20_RS09600	COG0505	Belongs to the CarA family
BUN20_RS09615	COG0067	glutamate synthase
BUN20_RS09615	COG0069	glutamate synthase activity
BUN20_RS09615	COG0070	glutamate synthase
BUN20_RS09625	COG0367	asparagine synthase
BUN20_RS09640	COG3275	phosphorelay sensor kinase activity
BUN20_RS09670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BUN20_RS09680	COG1979	alcohol dehydrogenase
BUN20_RS09690	COG0133	tryptophan synthase activity
BUN20_RS09695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUN20_RS09710	COG0134	indole-3-glycerol-phosphate synthase activity
BUN20_RS09715	COG0135	phosphoribosylanthranilate isomerase activity
BUN20_RS09720	COG0159	tryptophan synthase activity
BUN20_RS09725	COG0252	asparaginase activity
BUN20_RS09735	COG0745	RESPONSE REGULATOR receiver
BUN20_RS09735	COG2205	protein histidine kinase activity
BUN20_RS09735	COG3292	Two component regulator propeller
BUN20_RS09740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUN20_RS09750	COG0110	maltose O-acetyltransferase activity
BUN20_RS09755	COG2197	response regulator
BUN20_RS09765	COG0138	bifunctional purine biosynthesis protein purh
BUN20_RS09770	COG0716	FMN binding
BUN20_RS09810	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BUN20_RS09920	COG4771	TonB-dependent receptor
BUN20_RS09925	COG0702	epimerase
BUN20_RS09950	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BUN20_RS09960	COG1192	Involved in chromosome partitioning
BUN20_RS09990	COG1196	nuclear chromosome segregation
BUN20_RS09990	COG0741	lytic transglycosylase activity
BUN20_RS09990	COG0739	heme binding
BUN20_RS10165	COG4771	TonB-dependent receptor
BUN20_RS10180	COG2814	Major facilitator Superfamily
BUN20_RS10185	COG1566	PFAM secretion protein HlyD family protein
BUN20_RS10220	COG4771	TonB-dependent receptor
BUN20_RS10250	COG3610	response to peptide
BUN20_RS10265	COG1609	Transcriptional regulator
BUN20_RS10275	COG1733	regulation of RNA biosynthetic process
BUN20_RS10285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN20_RS10285	COG2198	Histidine kinase
BUN20_RS10285	COG2205	protein histidine kinase activity
BUN20_RS10285	COG0784	Response regulator, receiver
BUN20_RS10295	COG5002	protein histidine kinase activity
BUN20_RS10300	COG0745	RESPONSE REGULATOR receiver
BUN20_RS10320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BUN20_RS10325	COG1690	Belongs to the RtcB family
BUN20_RS10345	COG0228	four-way junction DNA binding
BUN20_RS10365	COG0724	RNA recognition motif
BUN20_RS10375	COG1177	transmembrane transport
BUN20_RS10380	COG1176	ABC-type spermidine putrescine transport system, permease component I
BUN20_RS10390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN20_RS10405	COG0058	SHG alpha-glucan phosphorylase activity
BUN20_RS10415	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUN20_RS10435	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BUN20_RS10500	COG0745	RESPONSE REGULATOR receiver
BUN20_RS10505	COG5002	protein histidine kinase activity
BUN20_RS10535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUN20_RS10545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUN20_RS10555	COG4948	Mandelate Racemase Muconate Lactonizing
BUN20_RS10570	COG1295	ribonuclease BN
BUN20_RS10575	COG0778	Nitroreductase
BUN20_RS10585	COG0704	Plays a role in the regulation of phosphate uptake
BUN20_RS10590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUN20_RS10595	COG0581	inorganic phosphate transmembrane transporter activity
BUN20_RS10600	COG0573	inorganic phosphate transmembrane transporter activity
BUN20_RS10610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BUN20_RS10635	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUN20_RS10675	COG3023	N-Acetylmuramoyl-L-alanine amidase
BUN20_RS10760	COG0297	glycogen (starch) synthase activity
BUN20_RS10765	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BUN20_RS10775	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BUN20_RS10820	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BUN20_RS10820	COG0662	Cupin 2, conserved barrel domain protein
BUN20_RS10825	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BUN20_RS10880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUN20_RS10885	COG0167	dihydroorotate dehydrogenase activity
BUN20_RS10950	COG5002	protein histidine kinase activity
BUN20_RS10965	COG2172	sigma factor antagonist activity
BUN20_RS10990	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BUN20_RS11015	COG0497	DNA recombination
BUN20_RS11025	COG2176	DNA-directed DNA polymerase activity
BUN20_RS11025	COG5002	protein histidine kinase activity
BUN20_RS11030	COG0592	DNA-directed DNA polymerase activity
BUN20_RS11045	COG0321	lipoyl(octanoyl) transferase activity
BUN20_RS11045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUN20_RS11060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUN20_RS11065	COG0156	8-amino-7-oxononanoate synthase activity
BUN20_RS11170	COG0019	diaminopimelate decarboxylase activity
BUN20_RS11175	COG0527	aspartate kinase activity
BUN20_RS11180	COG2884	Cell division ATP-binding protein ftsE
BUN20_RS11185	COG0140	phosphoribosyl-ATP diphosphatase activity
BUN20_RS11185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BUN20_RS11190	COG0107	imidazoleglycerol-phosphate synthase activity
BUN20_RS11195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BUN20_RS11215	COG3586	endonuclease activity
BUN20_RS11255	COG1917	Cupin 2, conserved barrel domain protein
BUN20_RS11255	COG4977	sequence-specific DNA binding
BUN20_RS11265	COG0693	protein deglycase activity
BUN20_RS11280	COG0494	nUDIX hydrolase
BUN20_RS11295	COG3326	Membrane
BUN20_RS11400	COG0561	phosphatase activity
BUN20_RS11405	COG4206	TonB-dependent receptor
BUN20_RS11405	COG1629	transport
BUN20_RS11465	COG0363	glucosamine-6-phosphate deaminase activity
BUN20_RS11505	COG1032	radical SAM domain protein
BUN20_RS11510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUN20_RS11515	COG0463	Glycosyl transferase, family 2
BUN20_RS11520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUN20_RS11525	COG1410	methionine synthase
BUN20_RS11525	COG0646	methionine synthase
BUN20_RS11565	COG1408	metallophosphoesterase
BUN20_RS11570	COG1132	(ABC) transporter
BUN20_RS11575	COG1132	(ABC) transporter
BUN20_RS11595	COG0420	3'-5' exonuclease activity
BUN20_RS11630	COG0681	Belongs to the peptidase S26 family
BUN20_RS11735	COG0641	radical SAM
BUN20_RS11740	COG3591	Belongs to the peptidase S1B family
BUN20_RS11745	COG3591	Belongs to the peptidase S1B family
BUN20_RS11775	COG1592	Rubrerythrin
BUN20_RS11775	COG1773	rubredoxin
BUN20_RS11785	COG3152	Membrane
BUN20_RS11790	COG0339	signal peptide processing
BUN20_RS11795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUN20_RS11795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BUN20_RS11805	COG1629	transport
BUN20_RS11805	COG4206	TonB-dependent receptor
BUN20_RS11820	COG0131	Imidazoleglycerol-phosphate dehydratase
BUN20_RS11820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BUN20_RS11830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BUN20_RS11835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BUN20_RS11845	COG1741	Belongs to the pirin family
BUN20_RS11850	COG4232	protein-disulfide reductase activity
BUN20_RS11860	COG0572	uridine kinase
BUN20_RS11865	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BUN20_RS11870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN20_RS11880	COG0646	methionine synthase
BUN20_RS11880	COG1410	methionine synthase
BUN20_RS11885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BUN20_RS11920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN20_RS11930	COG1295	ribonuclease BN
BUN20_RS11940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS11945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUN20_RS11955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BUN20_RS11960	COG1215	transferase activity, transferring glycosyl groups
BUN20_RS11965	COG5492	domain, Protein
BUN20_RS11980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUN20_RS11985	COG1216	Glycosyl transferase, family 2
BUN20_RS12045	COG4974	Belongs to the 'phage' integrase family
BUN20_RS12100	COG2198	Histidine kinase
BUN20_RS12100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN20_RS12100	COG0784	Response regulator, receiver
BUN20_RS12100	COG2205	protein histidine kinase activity
BUN20_RS12340	COG2202	Pas domain
BUN20_RS12340	COG2205	protein histidine kinase activity
BUN20_RS12345	COG0534	Mate efflux family protein
BUN20_RS12350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUN20_RS12360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BUN20_RS12425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUN20_RS12465	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUN20_RS12475	COG0668	transmembrane transport
BUN20_RS12480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BUN20_RS12490	COG3250	beta-galactosidase activity
BUN20_RS12495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS12500	COG3119	arylsulfatase activity
BUN20_RS12505	COG3119	arylsulfatase activity
BUN20_RS12510	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS12515	COG0745	RESPONSE REGULATOR receiver
BUN20_RS12515	COG2205	protein histidine kinase activity
BUN20_RS12515	COG3292	Two component regulator propeller
BUN20_RS12520	COG1830	Aldolase
BUN20_RS12525	COG0588	phosphoglycerate mutase activity
BUN20_RS12535	COG1119	ATPase activity
BUN20_RS12540	COG3119	arylsulfatase activity
BUN20_RS12545	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS12555	COG1629	transport
BUN20_RS12555	COG4206	TonB-dependent receptor
BUN20_RS12570	COG1523	belongs to the glycosyl hydrolase 13 family
BUN20_RS12575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BUN20_RS12595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BUN20_RS12610	COG0126	phosphoglycerate kinase activity
BUN20_RS12625	COG2311	Membrane
BUN20_RS12680	COG0424	maF-like protein
BUN20_RS12685	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BUN20_RS12700	COG0778	Nitroreductase
BUN20_RS12705	COG0288	reversible hydration of carbon dioxide
BUN20_RS12720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN20_RS12730	COG5016	pyruvate
BUN20_RS12730	COG0511	ligase activity, forming carbon-carbon bonds
BUN20_RS12735	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BUN20_RS12750	COG0366	Alpha amylase catalytic
BUN20_RS12770	COG0191	fructose-bisphosphate aldolase activity
BUN20_RS12780	COG0254	rRNA binding
BUN20_RS12805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BUN20_RS12810	COG1629	transport
BUN20_RS12810	COG4206	TonB-dependent receptor
BUN20_RS12815	COG1609	Transcriptional regulator
BUN20_RS12865	COG1554	hydrolase, family 65, central catalytic
BUN20_RS12870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS12895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUN20_RS12895	COG0047	phosphoribosylformylglycinamidine synthase activity
BUN20_RS12900	COG2205	protein histidine kinase activity
BUN20_RS12900	COG3292	Two component regulator propeller
BUN20_RS12900	COG0745	RESPONSE REGULATOR receiver
BUN20_RS12915	COG1649	PFAM Uncharacterised BCR, COG1649
BUN20_RS12925	COG4974	Belongs to the 'phage' integrase family
BUN20_RS12965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUN20_RS12965	COG0551	DNA topoisomerase type I activity
BUN20_RS12985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS13005	COG0577	efflux transmembrane transporter activity
BUN20_RS13150	COG0358	DNA primase activity
BUN20_RS13245	COG1966	Carbon starvation protein
BUN20_RS13255	COG1649	PFAM Uncharacterised BCR, COG1649
BUN20_RS13300	COG2113	Glycine betaine
BUN20_RS13305	COG4176	ABC-type proline glycine betaine transport system permease component
BUN20_RS13320	COG0745	RESPONSE REGULATOR receiver
BUN20_RS13320	COG2205	protein histidine kinase activity
BUN20_RS13320	COG3292	Two component regulator propeller
BUN20_RS13325	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BUN20_RS13325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BUN20_RS13335	COG1621	beta-fructofuranosidase activity
BUN20_RS13405	COG0738	Major facilitator superfamily
BUN20_RS13420	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN20_RS13425	COG0475	glutathione-regulated potassium exporter activity
BUN20_RS13450	COG3015	lipoprotein NlpE involved in copper resistance
BUN20_RS13460	COG3279	Response regulator of the LytR AlgR family
BUN20_RS13475	COG4206	TonB-dependent receptor
BUN20_RS13475	COG1629	transport
BUN20_RS13480	COG0702	epimerase
BUN20_RS13500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BUN20_RS13520	COG0484	heat shock protein binding
BUN20_RS13530	COG2194	sulfuric ester hydrolase activity
BUN20_RS13580	COG0028	Belongs to the TPP enzyme family
BUN20_RS13605	COG0459	protein refolding
BUN20_RS13610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BUN20_RS13650	COG2326	polyphosphate kinase activity
BUN20_RS13700	COG3537	Alpha-1,2-mannosidase
BUN20_RS13705	COG1506	peptidase
BUN20_RS13705	COG0823	Involved in the tonB-independent uptake of proteins
BUN20_RS13735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BUN20_RS13770	COG0514	ATP-dependent DNA helicase (RecQ)
BUN20_RS13785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN20_RS13795	COG0671	phosphoesterase, PA-phosphatase related
BUN20_RS13810	COG0702	epimerase
BUN20_RS13815	COG4206	TonB-dependent receptor
BUN20_RS13815	COG1629	transport
BUN20_RS13845	COG0463	Glycosyl transferase, family 2
BUN20_RS13860	COG0066	3-isopropylmalate dehydratase activity
BUN20_RS13865	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BUN20_RS13870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUN20_RS13930	COG0616	signal peptide processing
BUN20_RS13940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BUN20_RS13945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BUN20_RS14075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN20_RS14095	COG1917	Cupin 2, conserved barrel domain protein
BUN20_RS14095	COG2207	Transcriptional regulator
BUN20_RS14105	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS14125	COG0463	Glycosyl transferase, family 2
BUN20_RS14140	COG1971	Probably functions as a manganese efflux pump
BUN20_RS14145	COG1477	protein flavinylation
BUN20_RS14155	COG0037	tRNA processing
BUN20_RS14170	COG4864	UPF0365 protein
BUN20_RS14180	COG2176	DNA-directed DNA polymerase activity
BUN20_RS14185	COG2910	NAD(P)H-binding
BUN20_RS14190	COG2202	Pas domain
BUN20_RS14190	COG2205	protein histidine kinase activity
BUN20_RS14195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BUN20_RS14210	COG4974	Belongs to the 'phage' integrase family
BUN20_RS14240	COG1431	PFAM Stem cell self-renewal protein Piwi
BUN20_RS14250	COG1401	restriction endodeoxyribonuclease activity
BUN20_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS14305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUN20_RS14310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN20_RS14315	COG4651	solute:proton antiporter activity
BUN20_RS14315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUN20_RS14320	COG0439	Biotin carboxylase
BUN20_RS14325	COG0511	ligase activity, forming carbon-carbon bonds
BUN20_RS14330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUN20_RS14335	COG4977	sequence-specific DNA binding
BUN20_RS14335	COG1917	Cupin 2, conserved barrel domain protein
BUN20_RS14345	COG1335	isochorismatase
BUN20_RS14355	COG2202	Pas domain
BUN20_RS14355	COG2205	protein histidine kinase activity
BUN20_RS14360	COG2207	Transcriptional regulator
BUN20_RS14365	COG0516	GMP reductase activity
BUN20_RS14365	COG0517	IMP dehydrogenase activity
BUN20_RS14385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS14400	COG2873	o-acetylhomoserine
BUN20_RS14440	COG0110	maltose O-acetyltransferase activity
BUN20_RS14450	COG2076	Multidrug Resistance protein
BUN20_RS14490	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUN20_RS14500	COG1388	LysM domain
BUN20_RS14500	COG0741	lytic transglycosylase activity
BUN20_RS14505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUN20_RS14510	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BUN20_RS14510	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BUN20_RS14520	COG1285	pathogenesis
BUN20_RS14540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUN20_RS14540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUN20_RS14555	COG1115	amino acid carrier protein
BUN20_RS14565	COG1509	lysine 2,3-aminomutase activity
BUN20_RS14570	COG2233	PERMEase
BUN20_RS14585	COG1393	Belongs to the ArsC family
BUN20_RS14595	COG1629	transport
BUN20_RS14605	COG2304	oxidoreductase activity
BUN20_RS14615	COG0351	phosphomethylpyrimidine kinase
BUN20_RS14625	COG1139	Iron-sulfur cluster binding protein
BUN20_RS14630	COG0247	lactate metabolic process
BUN20_RS14635	COG0602	queuosine metabolic process
BUN20_RS14645	COG2832	Protein of unknown function (DUF454)
BUN20_RS14650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUN20_RS14665	COG3142	Participates in the control of copper homeostasis
BUN20_RS14670	COG1418	mRNA catabolic process
BUN20_RS14695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUN20_RS14710	COG4771	TonB-dependent receptor
BUN20_RS14740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUN20_RS14745	COG1061	Type III restriction enzyme res subunit
BUN20_RS14750	COG1002	Type II restriction enzyme, methylase subunits
BUN20_RS14805	COG3340	Belongs to the peptidase S51 family
BUN20_RS14810	COG2378	regulation of single-species biofilm formation
BUN20_RS14865	COG1505	serine-type exopeptidase activity
BUN20_RS14895	COG0517	IMP dehydrogenase activity
BUN20_RS14895	COG0617	tRNA 3'-terminal CCA addition
BUN20_RS14895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUN20_RS14920	COG0612	Peptidase, M16
BUN20_RS14930	COG1278	Cold shock
BUN20_RS14965	COG1216	Glycosyl transferase, family 2
BUN20_RS14995	COG0110	maltose O-acetyltransferase activity
BUN20_RS15015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS15025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN20_RS15075	COG0776	regulation of translation
BUN20_RS15085	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BUN20_RS15105	COG0632	four-way junction helicase activity
BUN20_RS15110	COG0673	inositol 2-dehydrogenase activity
BUN20_RS15115	COG1272	protein, Hemolysin III
BUN20_RS15120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BUN20_RS15120	COG1328	CTP reductase activity
BUN20_RS15130	COG2814	Major facilitator Superfamily
BUN20_RS15140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUN20_RS15150	COG0750	zinc metalloprotease
BUN20_RS15155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BUN20_RS15165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BUN20_RS15170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BUN20_RS15180	COG1214	PFAM Peptidase M22, glycoprotease
BUN20_RS15185	COG2198	Histidine kinase
BUN20_RS15185	COG0784	Response regulator, receiver
BUN20_RS15185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN20_RS15185	COG2205	protein histidine kinase activity
BUN20_RS15200	COG0194	GDP metabolic process
BUN20_RS15205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUN20_RS15210	COG1408	metallophosphoesterase
BUN20_RS15215	COG1575	Belongs to the MenA family. Type 1 subfamily
BUN20_RS15220	COG1088	dTDP-glucose 4,6-dehydratase activity
BUN20_RS15225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BUN20_RS15235	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BUN20_RS15245	COG2204	response regulator
BUN20_RS15250	COG0488	(ABC) transporter
BUN20_RS15285	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BUN20_RS15285	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUN20_RS15310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUN20_RS15315	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BUN20_RS15325	COG1522	sequence-specific DNA binding
BUN20_RS15350	COG0811	peptide transport
BUN20_RS15360	COG0084	hydrolase, TatD family'
BUN20_RS15375	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BUN20_RS15380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BUN20_RS15385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BUN20_RS15390	COG0205	6-phosphofructokinase activity
BUN20_RS15410	COG0372	Belongs to the citrate synthase family
BUN20_RS15415	COG0538	isocitrate dehydrogenase activity
BUN20_RS15425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BUN20_RS15435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BUN20_RS15460	COG0129	dihydroxy-acid dehydratase activity
BUN20_RS15480	COG2885	chlorophyll binding
BUN20_RS15500	COG3681	Belongs to the UPF0597 family
BUN20_RS15535	COG3119	arylsulfatase activity
BUN20_RS15545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BUN20_RS15555	COG0702	epimerase
BUN20_RS15560	COG4771	TonB-dependent receptor
BUN20_RS15575	COG0702	epimerase
BUN20_RS15580	COG4206	TonB-dependent receptor
BUN20_RS15580	COG1629	transport
BUN20_RS15605	COG4771	TonB-dependent receptor
BUN20_RS15635	COG1012	belongs to the aldehyde dehydrogenase family
BUN20_RS15675	COG4771	TonB-dependent receptor
BUN20_RS15685	COG3250	beta-galactosidase activity
BUN20_RS15695	COG3250	beta-galactosidase activity
BUN20_RS15700	COG3250	beta-galactosidase activity
BUN20_RS15720	COG4771	TonB-dependent receptor
BUN20_RS15760	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUN20_RS15760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUN20_RS15765	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUN20_RS15790	COG0534	Mate efflux family protein
BUN20_RS15815	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUN20_RS15825	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BUN20_RS15830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BUN20_RS15835	COG0166	Belongs to the GPI family
BUN20_RS15845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUN20_RS15855	COG2502	aspartate--ammonia ligase
BUN20_RS15860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BUN20_RS15875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS15895	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUN20_RS15905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BUN20_RS15920	COG1640	4-alpha-glucanotransferase
BUN20_RS15930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUN20_RS15935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUN20_RS15960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUN20_RS15965	COG1022	Amp-dependent synthetase and ligase
BUN20_RS15980	COG0359	binds to the 23S rRNA
BUN20_RS15985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BUN20_RS15990	COG0360	Binds together with S18 to 16S ribosomal RNA
BUN20_RS16010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BUN20_RS16040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUN20_RS16060	COG4771	TonB-dependent receptor
BUN20_RS16075	COG2431	L-lysine efflux transmembrane transporter activity
BUN20_RS16125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BUN20_RS16130	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BUN20_RS16135	COG0386	Belongs to the glutathione peroxidase family
BUN20_RS16155	COG3275	phosphorelay sensor kinase activity
BUN20_RS16160	COG3279	Response regulator of the LytR AlgR family
BUN20_RS16170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BUN20_RS16180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BUN20_RS16195	COG3250	beta-galactosidase activity
BUN20_RS16200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUN20_RS16210	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUN20_RS16215	COG0658	competence protein
BUN20_RS16220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BUN20_RS16225	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BUN20_RS16235	COG0009	L-threonylcarbamoyladenylate synthase
BUN20_RS16265	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BUN20_RS16320	COG2244	polysaccharide biosynthetic process
BUN20_RS16360	COG0519	Catalyzes the synthesis of GMP from XMP
BUN20_RS16370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUN20_RS16370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUN20_RS16375	COG0514	ATP-dependent DNA helicase (RecQ)
BUN20_RS16390	COG0436	Aminotransferase
BUN20_RS16395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUN20_RS16415	COG0358	DNA primase activity
BUN20_RS16420	COG3119	arylsulfatase activity
BUN20_RS16425	COG0702	epimerase
BUN20_RS16430	COG4206	TonB-dependent receptor
BUN20_RS16430	COG1629	transport
BUN20_RS16445	COG0302	gtp cyclohydrolase
BUN20_RS16455	COG0149	triose-phosphate isomerase activity
BUN20_RS16470	COG0739	heme binding
BUN20_RS16475	COG0105	UTP biosynthetic process
BUN20_RS16480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUN20_RS16505	COG0811	peptide transport
BUN20_RS16515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUN20_RS16560	COG1629	transport
BUN20_RS16590	COG4946	Tricorn protease homolog
BUN20_RS16590	COG1506	peptidase
BUN20_RS16590	COG0823	Involved in the tonB-independent uptake of proteins
BUN20_RS16595	COG0039	L-malate dehydrogenase activity
BUN20_RS16645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS16660	COG4948	Mandelate Racemase Muconate Lactonizing
BUN20_RS16685	COG3118	belongs to the thioredoxin family
BUN20_RS16690	COG0489	protein tyrosine kinase activity
BUN20_RS16705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUN20_RS16715	COG1570	exodeoxyribonuclease VII activity
BUN20_RS16725	COG0482	sulfurtransferase activity
BUN20_RS16745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BUN20_RS16750	COG0179	Fumarylacetoacetate (FAA) hydrolase
BUN20_RS16755	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BUN20_RS16765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BUN20_RS16770	COG0052	Belongs to the universal ribosomal protein uS2 family
BUN20_RS16775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BUN20_RS16780	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUN20_RS16795	COG0017	Asparaginyl-tRNA synthetase
BUN20_RS16800	COG1187	pseudouridine synthase activity
BUN20_RS16840	COG0110	maltose O-acetyltransferase activity
BUN20_RS16845	COG3022	response to hydroperoxide
BUN20_RS16850	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS16910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BUN20_RS16950	COG1216	Glycosyl transferase, family 2
BUN20_RS16975	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BUN20_RS16995	COG0297	glycogen (starch) synthase activity
BUN20_RS17020	COG0745	RESPONSE REGULATOR receiver
BUN20_RS17085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BUN20_RS17100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUN20_RS17115	COG0517	IMP dehydrogenase activity
BUN20_RS17115	COG0516	GMP reductase activity
BUN20_RS17120	COG0514	ATP-dependent DNA helicase (RecQ)
BUN20_RS17125	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BUN20_RS17135	COG0544	peptidyl-prolyl cis-trans isomerase activity
BUN20_RS17150	COG0724	RNA recognition motif
BUN20_RS17160	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BUN20_RS17165	COG1127	ABC transporter
BUN20_RS17170	COG0745	RESPONSE REGULATOR receiver
BUN20_RS17175	COG1160	GTP binding
BUN20_RS17180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BUN20_RS17185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUN20_RS17245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BUN20_RS17250	COG0470	DNA polymerase III
BUN20_RS17255	COG1774	PSP1 C-terminal conserved region
BUN20_RS17265	COG0772	Belongs to the SEDS family
BUN20_RS17280	COG1792	Involved in formation and maintenance of cell shape
BUN20_RS17290	COG0138	bifunctional purine biosynthesis protein purh
BUN20_RS17295	COG3590	peptidase
BUN20_RS17300	COG0488	(ABC) transporter
BUN20_RS17310	COG1216	Glycosyl transferase, family 2
BUN20_RS17325	COG0297	glycogen (starch) synthase activity
BUN20_RS17375	COG0784	Response regulator, receiver
BUN20_RS17375	COG2205	protein histidine kinase activity
BUN20_RS17380	COG0534	Mate efflux family protein
BUN20_RS17385	COG0612	Peptidase, M16
BUN20_RS17390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BUN20_RS17405	COG0564	pseudouridine synthase activity
BUN20_RS17445	COG1131	(ABC) transporter
BUN20_RS17545	COG1696	Membrane protein involved in D-alanine export
BUN20_RS17580	COG1309	transcriptional regulator
BUN20_RS17585	COG2986	histidine ammonia-lyase
BUN20_RS17595	COG1228	amidohydrolase
BUN20_RS17605	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BUN20_RS17620	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUN20_RS17635	COG0203	ribosomal protein L17
BUN20_RS17640	COG0202	RNA polymerase activity
BUN20_RS17645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BUN20_RS17650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BUN20_RS17655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BUN20_RS17660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUN20_RS17665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BUN20_RS17680	COG0200	Binds to the 23S rRNA
BUN20_RS17685	COG1841	ribosomal large subunit assembly
BUN20_RS17690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BUN20_RS17695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BUN20_RS17700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BUN20_RS17705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BUN20_RS17710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BUN20_RS17715	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BUN20_RS17720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BUN20_RS17725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BUN20_RS17730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BUN20_RS17735	COG0255	Belongs to the universal ribosomal protein uL29 family
BUN20_RS17740	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BUN20_RS17745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BUN20_RS17750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BUN20_RS17755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BUN20_RS17760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BUN20_RS17765	COG0089	rRNA binding
BUN20_RS17770	COG0088	Forms part of the polypeptide exit tunnel
BUN20_RS17775	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BUN20_RS17780	COG0051	transcription antitermination factor activity, RNA binding
BUN20_RS17785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BUN20_RS17790	COG0049	tRNA binding
BUN20_RS17795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BUN20_RS17825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BUN20_RS17830	COG0085	RNA polymerase activity
BUN20_RS17835	COG0222	ribosome binding
BUN20_RS17840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BUN20_RS17845	COG0081	regulation of translation
BUN20_RS17850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BUN20_RS17895	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BUN20_RS17900	COG4974	Belongs to the 'phage' integrase family
BUN20_RS17905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BUN20_RS17910	COG0006	proline dipeptidase activity
BUN20_RS17915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BUN20_RS17925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BUN20_RS17930	COG1480	7TM receptor with intracellular HD hydrolase
BUN20_RS17935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUN20_RS17945	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUN20_RS17960	COG1027	Aspartate ammonia-lyase
BUN20_RS17965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BUN20_RS17970	COG0252	asparaginase activity
BUN20_RS17985	COG2096	Adenosyltransferase
BUN20_RS18045	COG2755	lipolytic protein G-D-S-L family
BUN20_RS18045	COG0657	acetylesterase activity
BUN20_RS18060	COG3279	Response regulator of the LytR AlgR family
BUN20_RS18075	COG4206	TonB-dependent receptor
BUN20_RS18095	COG2197	response regulator
BUN20_RS18115	COG0662	Cupin 2, conserved barrel domain protein
BUN20_RS18115	COG2207	Transcriptional regulator
BUN20_RS18120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BUN20_RS18165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUN20_RS18195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BUN20_RS18205	COG1185	polyribonucleotide nucleotidyltransferase activity
BUN20_RS18220	COG4771	TonB-dependent receptor
BUN20_RS18270	COG3426	butyrate kinase activity
BUN20_RS18275	COG0280	phosphate acetyltransferase
BUN20_RS18285	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUN20_RS18290	COG2234	aminopeptidase activity
BUN20_RS18295	COG2166	iron-sulfur cluster assembly
BUN20_RS18300	COG3655	Transcriptional regulator
BUN20_RS18310	COG1266	CAAX protease self-immunity
BUN20_RS18315	COG0196	riboflavin kinase activity
BUN20_RS18320	COG1011	Hydrolase
BUN20_RS18325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUN20_RS18330	COG0784	Response regulator, receiver
BUN20_RS18330	COG5002	protein histidine kinase activity
BUN20_RS18335	COG1773	rubredoxin
BUN20_RS18340	COG1283	sodium-dependent phosphate transmembrane transporter activity
BUN20_RS18350	COG2205	protein histidine kinase activity
BUN20_RS18380	COG0006	proline dipeptidase activity
BUN20_RS18395	COG0509	glycine decarboxylation via glycine cleavage system
BUN20_RS18400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUN20_RS18430	COG0702	epimerase
BUN20_RS18435	COG4771	TonB-dependent receptor
BUN20_RS18450	COG0793	Belongs to the peptidase S41A family
BUN20_RS18455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN20_RS18490	COG4771	TonB-dependent receptor
BUN20_RS18495	COG2205	protein histidine kinase activity
BUN20_RS18495	COG3292	Two component regulator propeller
BUN20_RS18495	COG0745	RESPONSE REGULATOR receiver
BUN20_RS18500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BUN20_RS18505	COG1882	Formate acetyltransferase
BUN20_RS18510	COG2814	Major facilitator Superfamily
BUN20_RS18510	COG0477	Major facilitator Superfamily
BUN20_RS18535	COG0483	inositol monophosphate 1-phosphatase activity
BUN20_RS18545	COG3345	alpha-galactosidase
BUN20_RS18570	COG3475	LICD family
BUN20_RS18575	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BUN20_RS18655	COG0776	regulation of translation
BUN20_RS18660	COG1970	mechanosensitive ion channel activity
BUN20_RS18680	COG4771	TonB-dependent receptor
BUN20_RS18705	COG0745	RESPONSE REGULATOR receiver
BUN20_RS18705	COG2205	protein histidine kinase activity
BUN20_RS18705	COG3292	Two component regulator propeller
BUN20_RS18740	COG2816	NAD+ diphosphatase activity
BUN20_RS18800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUN20_RS18810	COG0674	pyruvate-flavodoxin oxidoreductase activity
BUN20_RS18810	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BUN20_RS18815	COG1013	pyruvate-flavodoxin oxidoreductase activity
BUN20_RS18820	COG0584	glycerophosphoryl diester phosphodiesterase
BUN20_RS18825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BUN20_RS18830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BUN20_RS18835	COG1629	transport
BUN20_RS18870	COG1629	transport
BUN20_RS18885	COG1217	gtp-binding protein TYPA
BUN20_RS18890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BUN20_RS18900	COG0318	PFAM AMP-dependent synthetase and ligase
BUN20_RS18905	COG3850	Histidine kinase
BUN20_RS18905	COG4999	Histidine kinase
BUN20_RS18905	COG3437	response regulator, receiver
BUN20_RS18905	COG2205	protein histidine kinase activity
BUN20_RS18935	COG1629	transport
BUN20_RS18935	COG4206	TonB-dependent receptor
BUN20_RS18955	COG4591	ABC-type transport system involved in lipoprotein release permease component
BUN20_RS18960	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BUN20_RS18975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BUN20_RS18980	COG4974	Belongs to the 'phage' integrase family
BUN20_RS18995	COG0606	chelatase, subunit chli
BUN20_RS19125	COG0438	transferase activity, transferring glycosyl groups
BUN20_RS19150	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BUN20_RS19155	COG0438	transferase activity, transferring glycosyl groups
BUN20_RS19165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BUN20_RS19170	COG0545	Peptidyl-prolyl cis-trans isomerase
BUN20_RS19175	COG0545	Peptidyl-prolyl cis-trans isomerase
BUN20_RS19180	COG1522	sequence-specific DNA binding
BUN20_RS19200	COG3275	phosphorelay sensor kinase activity
BUN20_RS19215	COG1566	PFAM secretion protein HlyD family protein
BUN20_RS19290	COG4206	TonB-dependent receptor
BUN20_RS19290	COG1629	transport
BUN20_RS19300	COG2814	Major facilitator Superfamily
BUN20_RS19335	COG2205	protein histidine kinase activity
BUN20_RS19335	COG3292	Two component regulator propeller
BUN20_RS19335	COG0745	RESPONSE REGULATOR receiver
BUN20_RS19340	COG1621	beta-fructofuranosidase activity
BUN20_RS19390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BUN20_RS19395	COG0793	Belongs to the peptidase S41A family
BUN20_RS19395	COG3409	Peptidoglycan-binding domain 1 protein
BUN20_RS19430	COG1053	succinate dehydrogenase
BUN20_RS19435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BUN20_RS19460	COG0758	DNA mediated transformation
BUN20_RS19460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BUN20_RS19470	COG0826	peptidase U32
BUN20_RS19480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUN20_RS19495	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUN20_RS19500	COG0557	exoribonuclease II activity
BUN20_RS19525	COG1595	DNA-templated transcription, initiation
BUN20_RS19545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUN20_RS19560	COG0012	GTP binding
BUN20_RS19565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUN20_RS19570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BUN20_RS19580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUN20_RS19595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUN20_RS19615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BUN20_RS19635	COG0731	radical SAM domain protein
BUN20_RS19635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BUN20_RS19660	COG0659	secondary active sulfate transmembrane transporter activity
BUN20_RS19665	COG1592	Rubrerythrin
BUN20_RS19670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BUN20_RS19690	COG0427	acetyl-CoA hydrolase
BUN20_RS19700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUN20_RS19710	COG3250	beta-galactosidase activity
BUN20_RS19815	COG2177	Part of the ABC transporter FtsEX involved in
BUN20_RS19825	COG1968	undecaprenyl-diphosphatase activity
BUN20_RS19830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BUN20_RS19835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BUN20_RS19840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUN20_RS19850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BUN20_RS19855	COG1611	Belongs to the LOG family
BUN20_RS19870	COG0594	ribonuclease P activity
BUN20_RS19875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BUN20_RS19880	COG0084	hydrolase, TatD family'
BUN20_RS19890	COG0823	Involved in the tonB-independent uptake of proteins
BUN20_RS19890	COG4946	Tricorn protease homolog
BUN20_RS19890	COG1506	peptidase
BUN20_RS19900	COG3119	arylsulfatase activity
BUN20_RS19905	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BUN20_RS19910	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS19915	COG4677	pectinesterase activity
BUN20_RS19920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BUN20_RS19985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUN20_RS19985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BUN20_RS20005	COG1506	peptidase
BUN20_RS20005	COG0823	Involved in the tonB-independent uptake of proteins
BUN20_RS20010	COG0116	Belongs to the methyltransferase superfamily
BUN20_RS20010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUN20_RS20015	COG1045	serine acetyltransferase
BUN20_RS20020	COG3275	phosphorelay sensor kinase activity
BUN20_RS20025	COG3279	Response regulator of the LytR AlgR family
BUN20_RS20035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN20_RS20035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUN20_RS20055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BUN20_RS20060	COG1694	Mazg nucleotide pyrophosphohydrolase
BUN20_RS20070	COG0322	excinuclease ABC activity
BUN20_RS20075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUN20_RS20105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BUN20_RS20110	COG2715	membrane protein required for spore maturation
BUN20_RS20120	COG2255	four-way junction helicase activity
BUN20_RS20135	COG3591	Belongs to the peptidase S1B family
BUN20_RS20145	COG0513	Belongs to the DEAD box helicase family
BUN20_RS20155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUN20_RS20170	COG0612	Peptidase, M16
BUN20_RS20190	COG1312	Catalyzes the dehydration of D-mannonate
BUN20_RS20195	COG1028	Short-chain dehydrogenase reductase Sdr
BUN20_RS20205	COG0681	Belongs to the peptidase S26 family
BUN20_RS20215	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BUN20_RS20245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BUN20_RS20260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS20265	COG3250	beta-galactosidase activity
BUN20_RS20285	COG0215	cysteine-tRNA ligase activity
BUN20_RS20295	COG0561	phosphatase activity
BUN20_RS20325	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUN20_RS20390	COG0205	6-phosphofructokinase activity
BUN20_RS20400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUN20_RS20405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BUN20_RS20410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUN20_RS20415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUN20_RS20425	COG1216	Glycosyl transferase, family 2
BUN20_RS20445	COG1442	glycosyl transferase family 8
BUN20_RS20450	COG1216	Glycosyl transferase, family 2
BUN20_RS20450	COG1442	glycosyl transferase family 8
BUN20_RS20460	COG1442	glycosyl transferase family 8
BUN20_RS20460	COG1216	Glycosyl transferase, family 2
BUN20_RS20465	COG1132	(ABC) transporter
BUN20_RS20470	COG0328	RNA-DNA hybrid ribonuclease activity
BUN20_RS20470	COG3341	Caulimovirus viroplasmin
BUN20_RS20480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUN20_RS20490	COG0326	Molecular chaperone. Has ATPase activity
BUN20_RS20500	COG1166	arginine decarboxylase activity
BUN20_RS20505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BUN20_RS20510	COG1595	DNA-templated transcription, initiation
BUN20_RS20555	COG1454	alcohol dehydrogenase
BUN20_RS20565	COG1070	Carbohydrate kinase
BUN20_RS20570	COG0738	Major facilitator superfamily
BUN20_RS20590	COG0779	Required for maturation of 30S ribosomal subunits
BUN20_RS20595	COG0195	Participates in both transcription termination and antitermination
BUN20_RS20600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BUN20_RS20610	COG0719	Fe-S assembly protein
BUN20_RS20620	COG0396	ATPase activity
BUN20_RS20625	COG0719	Fe-S assembly protein
BUN20_RS20630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUN20_RS20635	COG0393	Putative heavy-metal-binding
BUN20_RS20640	COG3345	alpha-galactosidase
BUN20_RS20650	COG4771	TonB-dependent receptor
BUN20_RS20675	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BUN20_RS20680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BUN20_RS20705	COG0187	DNA topoisomerase II activity
BUN20_RS20710	COG0268	Binds directly to 16S ribosomal RNA
BUN20_RS20725	COG1381	Involved in DNA repair and RecF pathway recombination
BUN20_RS20730	COG1610	YqeY-like protein
BUN20_RS20735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUN20_RS20750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BUN20_RS20755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUN20_RS20760	COG0772	Belongs to the SEDS family
BUN20_RS20770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUN20_RS20775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUN20_RS20790	COG0275	rRNA processing
BUN20_RS20795	COG2001	Belongs to the MraZ family
BUN20_RS20815	COG4771	TonB-dependent receptor
BUN20_RS20845	COG0756	dUTP diphosphatase activity
BUN20_RS20860	COG4942	peptidase
BUN20_RS20865	COG0745	RESPONSE REGULATOR receiver
BUN20_RS20865	COG2205	protein histidine kinase activity
BUN20_RS20865	COG3292	Two component regulator propeller
BUN20_RS20870	COG3940	Belongs to the glycosyl hydrolase 43 family
BUN20_RS20880	COG3250	beta-galactosidase activity
BUN20_RS20910	COG0383	alpha-mannosidase activity
BUN20_RS20910	COG0383	alpha-mannosidase activity
BUN20_RS20935	COG3507	Belongs to the glycosyl hydrolase 43 family
BUN20_RS20975	COG3537	Alpha-1,2-mannosidase
BUN20_RS20985	COG2017	converts alpha-aldose to the beta-anomer
BUN20_RS21045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUN20_RS21050	COG1022	Amp-dependent synthetase and ligase
BUN20_RS21055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BUN20_RS21065	COG2954	triphosphatase activity
BUN20_RS21085	COG3250	beta-galactosidase activity
BUN20_RS21090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BUN20_RS21095	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BUN20_RS21100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BUN20_RS21120	COG4206	TonB-dependent receptor
BUN20_RS21120	COG1629	transport
BUN20_RS21125	COG0745	RESPONSE REGULATOR receiver
BUN20_RS21125	COG3292	Two component regulator propeller
BUN20_RS21125	COG2205	protein histidine kinase activity
BUN20_RS21130	COG2205	protein histidine kinase activity
BUN20_RS21130	COG0745	RESPONSE REGULATOR receiver
BUN20_RS21130	COG3292	Two component regulator propeller
BUN20_RS21155	COG4771	TonB-dependent receptor
BUN20_RS21165	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BUN20_RS21200	COG4771	TonB-dependent receptor
BUN20_RS21225	COG0423	glycine-tRNA ligase activity
BUN20_RS21230	COG0545	Peptidyl-prolyl cis-trans isomerase
BUN20_RS21240	COG3005	denitrification pathway
BUN20_RS21245	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BUN20_RS21255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUN20_RS21275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BUN20_RS21295	COG3876	Protein conserved in bacteria
BUN20_RS21315	COG1216	Glycosyl transferase, family 2
BUN20_RS21315	COG0463	Glycosyl transferase, family 2
BUN20_RS21330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUN20_RS21335	COG3876	Protein conserved in bacteria
BUN20_RS21345	COG1629	transport
BUN20_RS21345	COG4206	TonB-dependent receptor
BUN20_RS21355	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUN20_RS21360	COG0475	glutathione-regulated potassium exporter activity
BUN20_RS21360	COG0589	response to stress
BUN20_RS21365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BUN20_RS21380	COG0733	neurotransmitter:sodium symporter activity
BUN20_RS21390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUN20_RS21400	COG0076	glutamate decarboxylase activity
BUN20_RS21405	COG2066	Belongs to the glutaminase family
BUN20_RS21410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUN20_RS21410	COG2205	protein histidine kinase activity
BUN20_RS21415	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUN20_RS21420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUN20_RS21535	COG1346	cytolysis
BUN20_RS21560	COG0280	phosphate acetyltransferase
BUN20_RS21565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BUN20_RS21570	COG1785	Belongs to the alkaline phosphatase family
BUN20_RS21580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BUN20_RS21585	COG2003	Belongs to the UPF0758 family
BUN20_RS21590	COG1216	Glycosyl transferase, family 2
BUN20_RS21590	COG0463	Glycosyl transferase, family 2
BUN20_RS21595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BUN20_RS21600	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BUN20_RS21605	COG2815	serine threonine protein kinase
BUN20_RS21605	COG0515	serine threonine protein kinase
BUN20_RS21610	COG0564	pseudouridine synthase activity
BUN20_RS21630	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BUN20_RS21650	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BUN20_RS21655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUN20_RS21665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BUN20_RS21685	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BUN20_RS21695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN20_RS21695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUN20_RS21700	COG2890	protein-(glutamine-N5) methyltransferase activity
BUN20_RS21705	COG2137	regulation of response to DNA damage stimulus
BUN20_RS21710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BUN20_RS21735	COG1929	Belongs to the glycerate kinase type-1 family
BUN20_RS21745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUN20_RS21750	COG1396	sequence-specific DNA binding
BUN20_RS21750	COG1917	Cupin 2, conserved barrel domain protein
BUN20_RS21755	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUN20_RS21760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUN20_RS21765	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BUN20_RS21770	COG0137	argininosuccinate synthase activity
BUN20_RS21950	COG3437	response regulator, receiver
BUN20_RS21950	COG4999	Histidine kinase
BUN20_RS21950	COG3850	Histidine kinase
BUN20_RS21950	COG2205	protein histidine kinase activity
BUN20_RS21955	COG0531	amino acid
BUN20_RS21970	COG0039	L-malate dehydrogenase activity
BUN20_RS21975	COG2996	Protein conserved in bacteria
BUN20_RS22005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUN20_RS22010	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUN20_RS22030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUN20_RS22035	COG0577	efflux transmembrane transporter activity
BUN20_RS22035	COG1136	(ABC) transporter
BUN20_RS22040	COG0577	efflux transmembrane transporter activity
BUN20_RS22040	COG1136	(ABC) transporter
BUN20_RS22045	COG1136	(ABC) transporter
BUN20_RS22050	COG1940	carbohydrate kinase activity
BUN20_RS22060	COG0335	large ribosomal subunit rRNA binding
BUN20_RS22065	COG0737	Belongs to the 5'-nucleotidase family
BUN20_RS22070	COG0737	Belongs to the 5'-nucleotidase family
BUN20_RS22075	COG1472	Belongs to the glycosyl hydrolase 3 family
BUN20_RS22080	COG1472	Belongs to the glycosyl hydrolase 3 family
BUN20_RS22085	COG1629	transport
BUN20_RS22085	COG4206	TonB-dependent receptor
BUN20_RS22095	COG3119	arylsulfatase activity
BUN20_RS22120	COG0446	pyridine nucleotide-disulphide oxidoreductase
BUN20_RS22130	COG2204	response regulator
BUN20_RS22140	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BUN20_RS22160	COG2205	protein histidine kinase activity
BUN20_RS22165	COG5002	protein histidine kinase activity
BUN20_RS22200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN20_RS22200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUN20_RS22205	COG0436	Aminotransferase
BUN20_RS22220	COG0826	peptidase U32
BUN20_RS22230	COG4771	TonB-dependent receptor
BUN20_RS22240	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BUN20_RS22250	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUN20_RS22260	COG0489	protein tyrosine kinase activity
BUN20_RS22260	COG3206	protein involved in exopolysaccharide biosynthesis
BUN20_RS22270	COG0527	aspartate kinase activity
BUN20_RS22270	COG0460	homoserine dehydrogenase
BUN20_RS22275	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BUN20_RS22330	COG4771	TonB-dependent receptor
BUN20_RS22345	COG2226	methyltransferase
BUN20_RS22405	COG1846	Transcriptional regulator
BUN20_RS22460	COG2076	Multidrug Resistance protein
BUN20_RS22470	COG4974	Belongs to the 'phage' integrase family
BUN20_RS22485	COG1435	thymidine kinase activity
BUN20_RS22495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUN20_RS22510	COG2095	MarC family integral membrane protein
BUN20_RS22520	COG1629	transport
BUN20_RS22520	COG4206	TonB-dependent receptor
BUN20_RS22530	COG4974	Belongs to the 'phage' integrase family
BUN20_RS22545	COG4771	TonB-dependent receptor
BUN20_RS22555	COG4771	TonB-dependent receptor
BUN20_RS22560	COG0702	epimerase
BUN20_RS22630	COG2131	deaminase
BUN20_RS22635	COG0793	Belongs to the peptidase S41A family
BUN20_RS22640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUN20_RS22695	COG4206	TonB-dependent receptor
BUN20_RS22695	COG1629	transport
BUN20_RS22705	COG4771	TonB-dependent receptor
BUN20_RS22735	COG0702	epimerase
BUN20_RS23055	COG0776	regulation of translation
BUN20_RS23095	COG1196	nuclear chromosome segregation
BUN20_RS23095	COG0739	heme binding
BUN20_RS23095	COG0741	lytic transglycosylase activity
BUN20_RS23125	COG4115	mRNA cleavage
BUN20_RS23230	COG4227	nucleotidyltransferase activity