locus-tag	class	description
BACHE_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BACHE_RS00010	COG0778	Nitroreductase
BACHE_RS00020	COG1640	4-alpha-glucanotransferase
BACHE_RS00025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BACHE_RS00055	COG1629	transport
BACHE_RS00055	COG4206	TonB-dependent receptor
BACHE_RS00080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACHE_RS00085	COG0318	PFAM AMP-dependent synthetase and ligase
BACHE_RS00095	COG0359	binds to the 23S rRNA
BACHE_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BACHE_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
BACHE_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BACHE_RS00135	COG3250	beta-galactosidase activity
BACHE_RS00140	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BACHE_RS00175	COG3275	phosphorelay sensor kinase activity
BACHE_RS00190	COG3119	arylsulfatase activity
BACHE_RS00200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BACHE_RS00210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BACHE_RS00220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BACHE_RS00225	COG2333	competence protein COMEC
BACHE_RS00225	COG0658	competence protein
BACHE_RS00235	COG3119	arylsulfatase activity
BACHE_RS00240	COG3119	arylsulfatase activity
BACHE_RS00250	COG4206	TonB-dependent receptor
BACHE_RS00250	COG1629	transport
BACHE_RS00255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BACHE_RS00260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BACHE_RS00270	COG0009	L-threonylcarbamoyladenylate synthase
BACHE_RS00280	COG2207	Transcriptional regulator
BACHE_RS00280	COG1609	Transcriptional regulator
BACHE_RS00285	COG5183	chlorophyll binding
BACHE_RS00285	COG2133	pyrroloquinoline quinone binding
BACHE_RS00290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS00305	COG1785	Belongs to the alkaline phosphatase family
BACHE_RS00315	COG3537	Alpha-1,2-mannosidase
BACHE_RS00325	COG4206	TonB-dependent receptor
BACHE_RS00325	COG1629	transport
BACHE_RS00350	COG3022	response to hydroperoxide
BACHE_RS00355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BACHE_RS00355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BACHE_RS00375	COG0436	Aminotransferase
BACHE_RS00380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BACHE_RS00390	COG0358	DNA primase activity
BACHE_RS00395	COG0302	gtp cyclohydrolase
BACHE_RS00405	COG0149	triose-phosphate isomerase activity
BACHE_RS00420	COG0739	heme binding
BACHE_RS00425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BACHE_RS00430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BACHE_RS00445	COG0848	biopolymer transport protein
BACHE_RS00450	COG0811	peptide transport
BACHE_RS00460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BACHE_RS00470	COG3250	beta-galactosidase activity
BACHE_RS00475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACHE_RS00490	COG4771	TonB-dependent receptor
BACHE_RS00495	COG2205	protein histidine kinase activity
BACHE_RS00495	COG3292	Two component regulator propeller
BACHE_RS00495	COG0745	RESPONSE REGULATOR receiver
BACHE_RS00500	COG3119	arylsulfatase activity
BACHE_RS00505	COG3119	arylsulfatase activity
BACHE_RS00515	COG4206	TonB-dependent receptor
BACHE_RS00515	COG1629	transport
BACHE_RS00530	COG0793	Belongs to the peptidase S41A family
BACHE_RS00530	COG4946	Tricorn protease homolog
BACHE_RS00535	COG0039	L-malate dehydrogenase activity
BACHE_RS00550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS00585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BACHE_RS00585	COG2885	chlorophyll binding
BACHE_RS00615	COG0673	inositol 2-dehydrogenase activity
BACHE_RS00630	COG1629	transport
BACHE_RS00655	COG0489	protein tyrosine kinase activity
BACHE_RS00660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BACHE_RS00665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BACHE_RS00675	COG1570	exodeoxyribonuclease VII activity
BACHE_RS00685	COG0482	sulfurtransferase activity
BACHE_RS00730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BACHE_RS00735	COG0179	Fumarylacetoacetate (FAA) hydrolase
BACHE_RS00740	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BACHE_RS00750	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BACHE_RS00755	COG0052	Belongs to the universal ribosomal protein uS2 family
BACHE_RS00760	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BACHE_RS00765	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BACHE_RS00775	COG0017	Asparaginyl-tRNA synthetase
BACHE_RS00780	COG1187	pseudouridine synthase activity
BACHE_RS00810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BACHE_RS00815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BACHE_RS00830	COG1629	transport
BACHE_RS00895	COG0551	DNA topoisomerase type I activity
BACHE_RS00895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BACHE_RS00905	COG4974	Belongs to the 'phage' integrase family
BACHE_RS00925	COG1733	regulation of RNA biosynthetic process
BACHE_RS00945	COG4974	Belongs to the 'phage' integrase family
BACHE_RS00965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BACHE_RS00980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BACHE_RS00990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BACHE_RS00995	COG0516	GMP reductase activity
BACHE_RS00995	COG0517	IMP dehydrogenase activity
BACHE_RS01000	COG0514	ATP-dependent DNA helicase (RecQ)
BACHE_RS01005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BACHE_RS01010	COG0740	serine-type endopeptidase activity
BACHE_RS01015	COG0544	peptidyl-prolyl cis-trans isomerase activity
BACHE_RS01030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BACHE_RS01035	COG1127	ABC transporter
BACHE_RS01040	COG2197	response regulator
BACHE_RS01045	COG1160	GTP binding
BACHE_RS01050	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BACHE_RS01055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BACHE_RS01110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BACHE_RS01120	COG2198	Histidine kinase
BACHE_RS01120	COG0784	Response regulator, receiver
BACHE_RS01120	COG2205	protein histidine kinase activity
BACHE_RS01125	COG0436	Aminotransferase
BACHE_RS01130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BACHE_RS01150	COG5002	protein histidine kinase activity
BACHE_RS01155	COG2205	protein histidine kinase activity
BACHE_RS01160	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BACHE_RS01170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BACHE_RS01175	COG2204	response regulator
BACHE_RS01185	COG2942	2-epimerase
BACHE_RS01190	COG2211	Major facilitator Superfamily
BACHE_RS01195	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BACHE_RS01200	COG4124	Belongs to the glycosyl hydrolase 26 family
BACHE_RS01225	COG4206	TonB-dependent receptor
BACHE_RS01225	COG1629	transport
BACHE_RS01235	COG3458	cephalosporin-C deacetylase activity
BACHE_RS01240	COG2207	Transcriptional regulator
BACHE_RS01240	COG0662	Cupin 2, conserved barrel domain protein
BACHE_RS01245	COG3250	beta-galactosidase activity
BACHE_RS01250	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS01255	COG0667	Aldo Keto reductase
BACHE_RS01260	COG4948	Mandelate Racemase Muconate Lactonizing
BACHE_RS01265	COG1629	transport
BACHE_RS01275	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS01280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BACHE_RS01285	COG0737	Belongs to the 5'-nucleotidase family
BACHE_RS01290	COG0737	Belongs to the 5'-nucleotidase family
BACHE_RS01295	COG0335	large ribosomal subunit rRNA binding
BACHE_RS01300	COG0668	transmembrane transport
BACHE_RS01305	COG3279	Response regulator of the LytR AlgR family
BACHE_RS01320	COG5002	protein histidine kinase activity
BACHE_RS01330	COG1940	carbohydrate kinase activity
BACHE_RS01335	COG0577	efflux transmembrane transporter activity
BACHE_RS01335	COG1136	(ABC) transporter
BACHE_RS01340	COG0577	efflux transmembrane transporter activity
BACHE_RS01340	COG1136	(ABC) transporter
BACHE_RS01345	COG1136	(ABC) transporter
BACHE_RS01345	COG0577	efflux transmembrane transporter activity
BACHE_RS01350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS01360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BACHE_RS01375	COG2996	Protein conserved in bacteria
BACHE_RS01410	COG0039	L-malate dehydrogenase activity
BACHE_RS01435	COG0702	epimerase
BACHE_RS01440	COG1629	transport
BACHE_RS01470	COG0137	argininosuccinate synthase activity
BACHE_RS01480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BACHE_RS01485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BACHE_RS01500	COG3275	phosphorelay sensor kinase activity
BACHE_RS01505	COG3279	Response regulator of the LytR AlgR family
BACHE_RS01515	COG2197	response regulator
BACHE_RS01565	COG1396	sequence-specific DNA binding
BACHE_RS01565	COG1917	Cupin 2, conserved barrel domain protein
BACHE_RS01570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BACHE_RS01665	COG0165	Argininosuccinate lyase
BACHE_RS01675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BACHE_RS01680	COG2137	regulation of response to DNA damage stimulus
BACHE_RS01685	COG2890	protein-(glutamine-N5) methyltransferase activity
BACHE_RS01700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BACHE_RS01705	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BACHE_RS01720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BACHE_RS01730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BACHE_RS01735	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BACHE_RS01740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BACHE_RS01765	COG0564	pseudouridine synthase activity
BACHE_RS01775	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BACHE_RS01780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BACHE_RS01785	COG0463	Glycosyl transferase, family 2
BACHE_RS01785	COG1216	Glycosyl transferase, family 2
BACHE_RS01790	COG2003	Belongs to the UPF0758 family
BACHE_RS01830	COG4771	TonB-dependent receptor
BACHE_RS01840	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACHE_RS01845	COG1785	Belongs to the alkaline phosphatase family
BACHE_RS01850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BACHE_RS01855	COG0280	phosphate acetyltransferase
BACHE_RS01885	COG1346	cytolysis
BACHE_RS01905	COG0312	modulator of DNA gyrase
BACHE_RS01910	COG0312	modulator of DNA gyrase
BACHE_RS01915	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BACHE_RS01920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BACHE_RS01925	COG2205	protein histidine kinase activity
BACHE_RS01925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BACHE_RS01930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BACHE_RS01940	COG0733	neurotransmitter:sodium symporter activity
BACHE_RS01975	COG1136	(ABC) transporter
BACHE_RS01985	COG1629	transport
BACHE_RS01995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BACHE_RS02000	COG0589	response to stress
BACHE_RS02000	COG0475	glutathione-regulated potassium exporter activity
BACHE_RS02005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BACHE_RS02015	COG4206	TonB-dependent receptor
BACHE_RS02015	COG1629	transport
BACHE_RS02025	COG1629	transport
BACHE_RS02025	COG4206	TonB-dependent receptor
BACHE_RS02030	COG0702	epimerase
BACHE_RS02035	COG3876	Protein conserved in bacteria
BACHE_RS02050	COG0463	Glycosyl transferase, family 2
BACHE_RS02050	COG1216	Glycosyl transferase, family 2
BACHE_RS02065	COG3876	Protein conserved in bacteria
BACHE_RS02085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BACHE_RS02090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BACHE_RS02100	COG0423	glycine-tRNA ligase activity
BACHE_RS02160	COG2954	triphosphatase activity
BACHE_RS02185	COG3023	N-Acetylmuramoyl-L-alanine amidase
BACHE_RS02265	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BACHE_RS02280	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS02290	COG1629	transport
BACHE_RS02290	COG4206	TonB-dependent receptor
BACHE_RS02300	COG0612	Peptidase, M16
BACHE_RS02305	COG1022	Amp-dependent synthetase and ligase
BACHE_RS02325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BACHE_RS02330	COG1629	transport
BACHE_RS02330	COG4206	TonB-dependent receptor
BACHE_RS02340	COG3119	arylsulfatase activity
BACHE_RS02345	COG2205	protein histidine kinase activity
BACHE_RS02350	COG4942	peptidase
BACHE_RS02365	COG0756	dUTP diphosphatase activity
BACHE_RS02385	COG1595	DNA-templated transcription, initiation
BACHE_RS02395	COG3250	beta-galactosidase activity
BACHE_RS02400	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS02405	COG3119	arylsulfatase activity
BACHE_RS02410	COG0702	epimerase
BACHE_RS02415	COG4206	TonB-dependent receptor
BACHE_RS02415	COG1629	transport
BACHE_RS02420	COG2205	protein histidine kinase activity
BACHE_RS02420	COG0745	RESPONSE REGULATOR receiver
BACHE_RS02420	COG2205	protein histidine kinase activity
BACHE_RS02420	COG3292	Two component regulator propeller
BACHE_RS02420	COG3292	Two component regulator propeller
BACHE_RS02420	COG0745	RESPONSE REGULATOR receiver
BACHE_RS02425	COG2001	Belongs to the MraZ family
BACHE_RS02440	COG0768	penicillin binding
BACHE_RS02445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BACHE_RS02450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACHE_RS02455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BACHE_RS02460	COG0772	Belongs to the SEDS family
BACHE_RS02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BACHE_RS02470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BACHE_RS02480	COG0849	cell division
BACHE_RS02485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BACHE_RS02495	COG1381	Involved in DNA repair and RecF pathway recombination
BACHE_RS02505	COG0268	Binds directly to 16S ribosomal RNA
BACHE_RS02510	COG0187	DNA topoisomerase II activity
BACHE_RS02525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BACHE_RS02535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BACHE_RS02545	COG4206	TonB-dependent receptor
BACHE_RS02545	COG1629	transport
BACHE_RS02550	COG0702	epimerase
BACHE_RS02560	COG2431	L-lysine efflux transmembrane transporter activity
BACHE_RS02565	COG3250	beta-galactosidase activity
BACHE_RS02570	COG3408	Glycogen debranching enzyme
BACHE_RS02570	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BACHE_RS02575	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BACHE_RS02580	COG0393	Putative heavy-metal-binding
BACHE_RS02600	COG4206	TonB-dependent receptor
BACHE_RS02600	COG1629	transport
BACHE_RS02615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BACHE_RS02620	COG0719	Fe-S assembly protein
BACHE_RS02625	COG0396	ATPase activity
BACHE_RS02630	COG0719	Fe-S assembly protein
BACHE_RS02640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BACHE_RS02645	COG0195	Participates in both transcription termination and antitermination
BACHE_RS02650	COG0779	Required for maturation of 30S ribosomal subunits
BACHE_RS02660	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS02665	COG2382	esterase
BACHE_RS02695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BACHE_RS02700	COG1166	arginine decarboxylase activity
BACHE_RS02705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BACHE_RS02720	COG4206	TonB-dependent receptor
BACHE_RS02720	COG1629	transport
BACHE_RS02725	COG3341	Caulimovirus viroplasmin
BACHE_RS02725	COG0328	RNA-DNA hybrid ribonuclease activity
BACHE_RS02730	COG1132	(ABC) transporter
BACHE_RS02735	COG1132	(ABC) transporter
BACHE_RS02755	COG1368	sulfuric ester hydrolase activity
BACHE_RS02790	COG1215	transferase activity, transferring glycosyl groups
BACHE_RS02795	COG1560	Kdo2-lipid A biosynthetic process
BACHE_RS02810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BACHE_RS02815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BACHE_RS02820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BACHE_RS02825	COG0571	ribonuclease III activity
BACHE_RS02830	COG0205	6-phosphofructokinase activity
BACHE_RS02845	COG0561	phosphatase activity
BACHE_RS02865	COG3119	arylsulfatase activity
BACHE_RS02870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACHE_RS02885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS02900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACHE_RS02925	COG3292	Two component regulator propeller
BACHE_RS02925	COG0745	RESPONSE REGULATOR receiver
BACHE_RS02925	COG2205	protein histidine kinase activity
BACHE_RS02925	COG2205	protein histidine kinase activity
BACHE_RS02925	COG0745	RESPONSE REGULATOR receiver
BACHE_RS02925	COG3292	Two component regulator propeller
BACHE_RS02930	COG3119	arylsulfatase activity
BACHE_RS02935	COG4771	TonB-dependent receptor
BACHE_RS02945	COG4771	TonB-dependent receptor
BACHE_RS02950	COG0702	epimerase
BACHE_RS02960	COG5492	domain, Protein
BACHE_RS02965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BACHE_RS02985	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BACHE_RS02995	COG0681	Belongs to the peptidase S26 family
BACHE_RS03005	COG2205	protein histidine kinase activity
BACHE_RS03005	COG2202	Pas domain
BACHE_RS03010	COG2202	Pas domain
BACHE_RS03010	COG2205	protein histidine kinase activity
BACHE_RS03015	COG2205	protein histidine kinase activity
BACHE_RS03015	COG2202	Pas domain
BACHE_RS03020	COG2202	Pas domain
BACHE_RS03020	COG2205	protein histidine kinase activity
BACHE_RS03030	COG1629	transport
BACHE_RS03030	COG4206	TonB-dependent receptor
BACHE_RS03045	COG1629	transport
BACHE_RS03050	COG0702	epimerase
BACHE_RS03060	COG3250	beta-galactosidase activity
BACHE_RS03065	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACHE_RS03070	COG3250	beta-galactosidase activity
BACHE_RS03075	COG1028	Short-chain dehydrogenase reductase Sdr
BACHE_RS03080	COG1312	Catalyzes the dehydration of D-mannonate
BACHE_RS03095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BACHE_RS03100	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS03105	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BACHE_RS03120	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BACHE_RS03125	COG0612	Peptidase, M16
BACHE_RS03135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BACHE_RS03145	COG0513	Belongs to the DEAD box helicase family
BACHE_RS03150	COG0783	Belongs to the Dps family
BACHE_RS03155	COG0583	DNA-binding transcription factor activity
BACHE_RS03165	COG3634	alkyl hydroperoxide reductase activity
BACHE_RS03170	COG3591	Belongs to the peptidase S1B family
BACHE_RS03185	COG2255	four-way junction helicase activity
BACHE_RS03265	COG5492	domain, Protein
BACHE_RS03280	COG2234	aminopeptidase activity
BACHE_RS03285	COG2715	membrane protein required for spore maturation
BACHE_RS03290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BACHE_RS03295	COG2017	converts alpha-aldose to the beta-anomer
BACHE_RS03305	COG3507	Belongs to the glycosyl hydrolase 43 family
BACHE_RS03320	COG4206	TonB-dependent receptor
BACHE_RS03320	COG1629	transport
BACHE_RS03325	COG0745	RESPONSE REGULATOR receiver
BACHE_RS03325	COG2205	protein histidine kinase activity
BACHE_RS03325	COG3292	Two component regulator propeller
BACHE_RS03340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BACHE_RS03345	COG0322	excinuclease ABC activity
BACHE_RS03350	COG1490	D-aminoacyl-tRNA deacylase activity
BACHE_RS03355	COG1694	Mazg nucleotide pyrophosphohydrolase
BACHE_RS03360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BACHE_RS03370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BACHE_RS03370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BACHE_RS03395	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACHE_RS03405	COG0012	GTP binding
BACHE_RS03415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BACHE_RS03425	COG1011	Hydrolase
BACHE_RS03430	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BACHE_RS03445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACHE_RS03450	COG2207	Transcriptional regulator
BACHE_RS03455	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BACHE_RS03455	COG2755	lipolytic protein G-D-S-L family
BACHE_RS03460	COG0346	lactoylglutathione lyase activity
BACHE_RS03495	COG1704	LemA family
BACHE_RS03540	COG0697	spore germination
BACHE_RS03545	COG0495	leucyl-tRNA aminoacylation
BACHE_RS03550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACHE_RS03555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BACHE_RS03560	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BACHE_RS03570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACHE_RS03575	COG2205	protein histidine kinase activity
BACHE_RS03575	COG2202	Pas domain
BACHE_RS03590	COG0731	radical SAM domain protein
BACHE_RS03590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BACHE_RS03605	COG0659	secondary active sulfate transmembrane transporter activity
BACHE_RS03620	COG1592	Rubrerythrin
BACHE_RS03670	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BACHE_RS03755	COG0427	acetyl-CoA hydrolase
BACHE_RS03765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACHE_RS03780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BACHE_RS03785	COG2177	Part of the ABC transporter FtsEX involved in
BACHE_RS03795	COG1968	undecaprenyl-diphosphatase activity
BACHE_RS03800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BACHE_RS03805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BACHE_RS03810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BACHE_RS03825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BACHE_RS03850	COG0594	ribonuclease P activity
BACHE_RS03855	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BACHE_RS03860	COG0084	hydrolase, TatD family'
BACHE_RS03865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BACHE_RS03880	COG1028	Short-chain dehydrogenase reductase Sdr
BACHE_RS03890	COG0726	polysaccharide deacetylase
BACHE_RS03910	COG3345	alpha-galactosidase
BACHE_RS03950	COG0151	Belongs to the GarS family
BACHE_RS03955	COG0823	Involved in the tonB-independent uptake of proteins
BACHE_RS03955	COG1506	peptidase
BACHE_RS03960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BACHE_RS03960	COG0116	Belongs to the methyltransferase superfamily
BACHE_RS03965	COG1045	serine acetyltransferase
BACHE_RS03985	COG4206	TonB-dependent receptor
BACHE_RS03985	COG1629	transport
BACHE_RS04010	COG0557	exoribonuclease II activity
BACHE_RS04015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BACHE_RS04030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BACHE_RS04040	COG0826	peptidase U32
BACHE_RS04050	COG0758	DNA mediated transformation
BACHE_RS04055	COG0584	glycerophosphoryl diester phosphodiesterase
BACHE_RS04065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BACHE_RS04070	COG1053	succinate dehydrogenase
BACHE_RS04085	COG0671	phosphoesterase, PA-phosphatase related
BACHE_RS04095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS04120	COG3409	Peptidoglycan-binding domain 1 protein
BACHE_RS04120	COG0793	Belongs to the peptidase S41A family
BACHE_RS04125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BACHE_RS04165	COG3119	arylsulfatase activity
BACHE_RS04175	COG3119	arylsulfatase activity
BACHE_RS04185	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BACHE_RS04195	COG2268	Band 7 protein
BACHE_RS04275	COG1522	sequence-specific DNA binding
BACHE_RS04280	COG0545	Peptidyl-prolyl cis-trans isomerase
BACHE_RS04285	COG0545	Peptidyl-prolyl cis-trans isomerase
BACHE_RS04290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BACHE_RS04300	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS04305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BACHE_RS04315	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS04325	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS04385	COG0606	chelatase, subunit chli
BACHE_RS04400	COG4974	Belongs to the 'phage' integrase family
BACHE_RS04405	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BACHE_RS04440	COG0671	phosphoesterase, PA-phosphatase related
BACHE_RS04465	COG0656	L-ascorbic acid biosynthetic process
BACHE_RS04480	COG1733	regulation of RNA biosynthetic process
BACHE_RS04490	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BACHE_RS04495	COG4591	ABC-type transport system involved in lipoprotein release permease component
BACHE_RS04505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BACHE_RS04510	COG1854	S-ribosylhomocysteine lyase activity
BACHE_RS04515	COG0318	PFAM AMP-dependent synthetase and ligase
BACHE_RS04520	COG1396	sequence-specific DNA binding
BACHE_RS04540	COG1396	sequence-specific DNA binding
BACHE_RS04550	COG3550	peptidyl-serine autophosphorylation
BACHE_RS04560	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BACHE_RS04565	COG1217	gtp-binding protein TYPA
BACHE_RS04580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BACHE_RS04585	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BACHE_RS04610	COG1013	pyruvate-flavodoxin oxidoreductase activity
BACHE_RS04615	COG0674	pyruvate-flavodoxin oxidoreductase activity
BACHE_RS04615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BACHE_RS04625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BACHE_RS04630	COG0339	signal peptide processing
BACHE_RS04655	COG0018	arginyl-trna synthetase
BACHE_RS04675	COG2816	NAD+ diphosphatase activity
BACHE_RS04680	COG0673	inositol 2-dehydrogenase activity
BACHE_RS04705	COG2176	DNA-directed DNA polymerase activity
BACHE_RS04730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BACHE_RS04735	COG0793	Belongs to the peptidase S41A family
BACHE_RS04740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BACHE_RS04745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BACHE_RS04750	COG0509	glycine decarboxylation via glycine cleavage system
BACHE_RS04765	COG3119	arylsulfatase activity
BACHE_RS04770	COG0006	proline dipeptidase activity
BACHE_RS04775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS04800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BACHE_RS04805	COG1283	sodium-dependent phosphate transmembrane transporter activity
BACHE_RS04810	COG1773	rubredoxin
BACHE_RS04815	COG2205	protein histidine kinase activity
BACHE_RS04815	COG0784	Response regulator, receiver
BACHE_RS04820	COG0463	Glycosyl transferase, family 2
BACHE_RS04840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BACHE_RS04845	COG1011	Hydrolase
BACHE_RS04850	COG0196	riboflavin kinase activity
BACHE_RS04860	COG1266	CAAX protease self-immunity
BACHE_RS04885	COG3655	Transcriptional regulator
BACHE_RS04890	COG2166	iron-sulfur cluster assembly
BACHE_RS04895	COG2234	aminopeptidase activity
BACHE_RS04905	COG0280	phosphate acetyltransferase
BACHE_RS04910	COG3426	butyrate kinase activity
BACHE_RS04915	COG1185	polyribonucleotide nucleotidyltransferase activity
BACHE_RS04925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BACHE_RS04935	COG0662	Cupin 2, conserved barrel domain protein
BACHE_RS04935	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BACHE_RS04955	COG0446	pyridine nucleotide-disulphide oxidoreductase
BACHE_RS04955	COG1902	pentaerythritol trinitrate reductase activity
BACHE_RS04960	COG1733	regulation of RNA biosynthetic process
BACHE_RS04990	COG1733	regulation of RNA biosynthetic process
BACHE_RS05005	COG4191	Histidine kinase
BACHE_RS05025	COG1136	(ABC) transporter
BACHE_RS05025	COG0577	efflux transmembrane transporter activity
BACHE_RS05030	COG0577	efflux transmembrane transporter activity
BACHE_RS05035	COG3507	Belongs to the glycosyl hydrolase 43 family
BACHE_RS05080	COG3292	Two component regulator propeller
BACHE_RS05080	COG2205	protein histidine kinase activity
BACHE_RS05080	COG0745	RESPONSE REGULATOR receiver
BACHE_RS05085	COG1501	Belongs to the glycosyl hydrolase 31 family
BACHE_RS05095	COG2096	Adenosyltransferase
BACHE_RS05105	COG0514	ATP-dependent DNA helicase (RecQ)
BACHE_RS05130	COG1979	alcohol dehydrogenase
BACHE_RS05135	COG4977	sequence-specific DNA binding
BACHE_RS05150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BACHE_RS05155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BACHE_RS05170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BACHE_RS05185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BACHE_RS05190	COG0006	proline dipeptidase activity
BACHE_RS05195	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BACHE_RS05200	COG4974	Belongs to the 'phage' integrase family
BACHE_RS05245	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BACHE_RS05250	COG0081	regulation of translation
BACHE_RS05255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BACHE_RS05260	COG0222	ribosome binding
BACHE_RS05265	COG0085	RNA polymerase activity
BACHE_RS05270	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BACHE_RS05280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BACHE_RS05285	COG0049	tRNA binding
BACHE_RS05290	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BACHE_RS05295	COG0051	transcription antitermination factor activity, RNA binding
BACHE_RS05300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BACHE_RS05305	COG0088	Forms part of the polypeptide exit tunnel
BACHE_RS05310	COG0089	rRNA binding
BACHE_RS05315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BACHE_RS05320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BACHE_RS05325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BACHE_RS05330	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BACHE_RS05335	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BACHE_RS05340	COG0255	Belongs to the universal ribosomal protein uL29 family
BACHE_RS05345	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BACHE_RS05350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BACHE_RS05355	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BACHE_RS05360	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BACHE_RS05365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BACHE_RS05370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BACHE_RS05375	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BACHE_RS05380	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BACHE_RS05385	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BACHE_RS05390	COG1841	ribosomal large subunit assembly
BACHE_RS05395	COG0200	Binds to the 23S rRNA
BACHE_RS05410	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BACHE_RS05415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BACHE_RS05420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BACHE_RS05425	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BACHE_RS05430	COG0202	RNA polymerase activity
BACHE_RS05435	COG0203	ribosomal protein L17
BACHE_RS05450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACHE_RS05460	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BACHE_RS05470	COG1228	amidohydrolase
BACHE_RS05480	COG2986	histidine ammonia-lyase
BACHE_RS05495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS05520	COG1696	Membrane protein involved in D-alanine export
BACHE_RS05590	COG1131	(ABC) transporter
BACHE_RS05610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS05630	COG0564	pseudouridine synthase activity
BACHE_RS05635	COG1506	peptidase
BACHE_RS05635	COG0823	Involved in the tonB-independent uptake of proteins
BACHE_RS05690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BACHE_RS05695	COG0612	Peptidase, M16
BACHE_RS05700	COG0534	Mate efflux family protein
BACHE_RS05730	COG1132	(ABC) transporter
BACHE_RS05770	COG0488	(ABC) transporter
BACHE_RS05775	COG3590	peptidase
BACHE_RS05780	COG0138	bifunctional purine biosynthesis protein purh
BACHE_RS05805	COG0772	Belongs to the SEDS family
BACHE_RS05815	COG1774	PSP1 C-terminal conserved region
BACHE_RS05820	COG0470	DNA polymerase III
BACHE_RS05825	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BACHE_RS05840	COG0826	peptidase U32
BACHE_RS05850	COG4771	TonB-dependent receptor
BACHE_RS05860	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BACHE_RS05865	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BACHE_RS05870	COG0252	asparaginase activity
BACHE_RS05875	COG0527	aspartate kinase activity
BACHE_RS05875	COG0460	homoserine dehydrogenase
BACHE_RS05880	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BACHE_RS05885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BACHE_RS05935	COG0628	permease
BACHE_RS05940	COG1435	thymidine kinase activity
BACHE_RS05950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BACHE_RS05965	COG2095	MarC family integral membrane protein
BACHE_RS05975	COG4206	TonB-dependent receptor
BACHE_RS05975	COG1629	transport
BACHE_RS05990	COG4771	TonB-dependent receptor
BACHE_RS06000	COG4771	TonB-dependent receptor
BACHE_RS06010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BACHE_RS06020	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BACHE_RS06020	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BACHE_RS06035	COG0233	cytoplasmic translational termination
BACHE_RS06040	COG0528	UMP kinase activity
BACHE_RS06045	COG2217	Heavy metal translocating P-type atpase
BACHE_RS06050	COG2207	Transcriptional regulator
BACHE_RS06050	COG1609	Transcriptional regulator
BACHE_RS06060	COG0534	Mate efflux family protein
BACHE_RS06095	COG2315	Protein conserved in bacteria
BACHE_RS06100	COG0792	nuclease activity
BACHE_RS06105	COG0793	Belongs to the peptidase S41A family
BACHE_RS06125	COG1183	phosphatidylcholine synthase activity
BACHE_RS06130	COG0688	phosphatidylethanolamine metabolic process
BACHE_RS06160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BACHE_RS06170	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BACHE_RS06180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BACHE_RS06190	COG4946	Tricorn protease homolog
BACHE_RS06190	COG0823	Involved in the tonB-independent uptake of proteins
BACHE_RS06190	COG1506	peptidase
BACHE_RS06195	COG0484	heat shock protein binding
BACHE_RS06215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BACHE_RS06230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BACHE_RS06235	COG0742	ribosomal rna small subunit methyltransferase
BACHE_RS06270	COG0739	heme binding
BACHE_RS06285	COG1388	LysM domain
BACHE_RS06285	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACHE_RS06295	COG1475	DNA binding
BACHE_RS06300	COG1192	Involved in chromosome partitioning
BACHE_RS06310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BACHE_RS06315	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACHE_RS06330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BACHE_RS06355	COG2239	Acts as a magnesium transporter
BACHE_RS06360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BACHE_RS06370	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACHE_RS06415	COG0784	Response regulator, receiver
BACHE_RS06415	COG2205	protein histidine kinase activity
BACHE_RS06415	COG2198	Histidine kinase
BACHE_RS06415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BACHE_RS06420	COG1119	ATPase activity
BACHE_RS06430	COG0668	transmembrane transport
BACHE_RS06435	COG5002	protein histidine kinase activity
BACHE_RS06440	COG0745	RESPONSE REGULATOR receiver
BACHE_RS06445	COG4771	TonB-dependent receptor
BACHE_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS06480	COG4412	M6 family metalloprotease domain protein
BACHE_RS06480	COG1404	Belongs to the peptidase S8 family
BACHE_RS06485	COG5002	protein histidine kinase activity
BACHE_RS06485	COG0784	Response regulator, receiver
BACHE_RS06485	COG2205	protein histidine kinase activity
BACHE_RS06505	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BACHE_RS06510	COG0713	ATP synthesis coupled electron transport
BACHE_RS06515	COG0839	Belongs to the complex I subunit 6 family
BACHE_RS06520	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACHE_RS06525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BACHE_RS06530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACHE_RS06530	COG0649	NAD binding
BACHE_RS06540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACHE_RS06550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BACHE_RS06555	COG0569	domain protein
BACHE_RS06560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BACHE_RS06570	COG1917	Cupin 2, conserved barrel domain protein
BACHE_RS06570	COG4977	sequence-specific DNA binding
BACHE_RS06575	COG1979	alcohol dehydrogenase
BACHE_RS06615	COG0667	Aldo Keto reductase
BACHE_RS06635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BACHE_RS06640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BACHE_RS06645	COG0805	protein transport
BACHE_RS06665	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BACHE_RS06670	COG3775	system Galactitol-specific IIC component
BACHE_RS06675	COG0546	phosphoglycolate phosphatase activity
BACHE_RS06680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BACHE_RS06685	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BACHE_RS06695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BACHE_RS06700	COG0823	Involved in the tonB-independent uptake of proteins
BACHE_RS06700	COG1506	peptidase
BACHE_RS06705	COG1242	4 iron, 4 sulfur cluster binding
BACHE_RS06715	COG0363	glucosamine-6-phosphate deaminase activity
BACHE_RS06760	COG0681	Belongs to the peptidase S26 family
BACHE_RS06805	COG0009	L-threonylcarbamoyladenylate synthase
BACHE_RS06815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BACHE_RS06820	COG0561	phosphatase activity
BACHE_RS06830	COG1073	alpha beta
BACHE_RS06845	COG1730	sister chromatid segregation
BACHE_RS06850	COG3487	Iron-regulated protein
BACHE_RS06875	COG1333	cytochrome c biogenesis protein
BACHE_RS06875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BACHE_RS06880	COG4566	intracellular signal transduction
BACHE_RS06895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS06905	COG3118	belongs to the thioredoxin family
BACHE_RS06915	COG4771	TonB-dependent receptor
BACHE_RS06920	COG0561	phosphatase activity
BACHE_RS06925	COG0745	RESPONSE REGULATOR receiver
BACHE_RS06925	COG2205	protein histidine kinase activity
BACHE_RS06925	COG2205	protein histidine kinase activity
BACHE_RS06925	COG0745	RESPONSE REGULATOR receiver
BACHE_RS06925	COG3292	Two component regulator propeller
BACHE_RS06925	COG3292	Two component regulator propeller
BACHE_RS06930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BACHE_RS06945	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BACHE_RS06945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BACHE_RS06950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACHE_RS06955	COG1078	dGTPase activity
BACHE_RS06960	COG0584	glycerophosphoryl diester phosphodiesterase
BACHE_RS06965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS06970	COG2755	lipolytic protein G-D-S-L family
BACHE_RS06970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BACHE_RS07000	COG2202	Pas domain
BACHE_RS07000	COG2205	protein histidine kinase activity
BACHE_RS07005	COG0284	orotidine-5'-phosphate decarboxylase activity
BACHE_RS07015	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BACHE_RS07035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BACHE_RS07045	COG3279	Response regulator of the LytR AlgR family
BACHE_RS07085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BACHE_RS07095	COG2226	methyltransferase
BACHE_RS07100	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BACHE_RS07105	COG1702	phosphate starvation-inducible protein PhoH
BACHE_RS07130	COG1496	oxidoreductase activity
BACHE_RS07135	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BACHE_RS07140	COG0563	adenylate kinase activity
BACHE_RS07145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BACHE_RS07170	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BACHE_RS07170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BACHE_RS07180	COG0101	tRNA pseudouridine synthase activity
BACHE_RS07190	COG1755	Isoprenylcysteine carboxyl methyltransferase
BACHE_RS07200	COG1956	GAF domain-containing protein
BACHE_RS07210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACHE_RS07225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BACHE_RS07250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BACHE_RS07255	COG0793	Belongs to the peptidase S41A family
BACHE_RS07260	COG2131	deaminase
BACHE_RS07270	COG0339	signal peptide processing
BACHE_RS07280	COG1970	mechanosensitive ion channel activity
BACHE_RS07285	COG0519	Catalyzes the synthesis of GMP from XMP
BACHE_RS07285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BACHE_RS07300	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS07315	COG0297	glycogen (starch) synthase activity
BACHE_RS07320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BACHE_RS07325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BACHE_RS07335	COG0543	2 iron, 2 sulfur cluster binding
BACHE_RS07350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BACHE_RS07355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BACHE_RS07360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BACHE_RS07365	COG0546	phosphoglycolate phosphatase activity
BACHE_RS07370	COG3537	Alpha-1,2-mannosidase
BACHE_RS07375	COG3537	Alpha-1,2-mannosidase
BACHE_RS07380	COG3537	Alpha-1,2-mannosidase
BACHE_RS07395	COG4206	TonB-dependent receptor
BACHE_RS07395	COG1629	transport
BACHE_RS07405	COG1629	transport
BACHE_RS07405	COG4206	TonB-dependent receptor
BACHE_RS07420	COG0515	serine threonine protein kinase
BACHE_RS07420	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BACHE_RS07445	COG2211	Major facilitator Superfamily
BACHE_RS07450	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BACHE_RS07455	COG3537	Alpha-1,2-mannosidase
BACHE_RS07465	COG0791	NLP P60 protein
BACHE_RS07470	COG1131	(ABC) transporter
BACHE_RS07480	COG0612	Peptidase, M16
BACHE_RS07485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BACHE_RS07490	COG1597	lipid kinase activity
BACHE_RS07495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BACHE_RS07515	COG0471	metal ion transport
BACHE_RS07515	COG0490	domain, Protein
BACHE_RS07550	COG2211	Major facilitator Superfamily
BACHE_RS07555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BACHE_RS07570	COG1674	ftsk spoiiie
BACHE_RS07580	COG0492	ferredoxin-NADP+ reductase activity
BACHE_RS07600	COG5146	pantothenate kinase activity
BACHE_RS07615	COG1595	DNA-templated transcription, initiation
BACHE_RS07630	COG3956	TIGRFAM MazG family protein
BACHE_RS07635	COG0693	protein deglycase activity
BACHE_RS07645	COG0525	valine-tRNA ligase activity
BACHE_RS07660	COG0653	protein targeting
BACHE_RS07665	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
BACHE_RS07675	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BACHE_RS07695	COG1253	flavin adenine dinucleotide binding
BACHE_RS07700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BACHE_RS07705	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BACHE_RS07715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BACHE_RS07760	COG1472	Belongs to the glycosyl hydrolase 3 family
BACHE_RS07770	COG2217	Heavy metal translocating P-type atpase
BACHE_RS07785	COG0534	Mate efflux family protein
BACHE_RS07820	COG3142	Participates in the control of copper homeostasis
BACHE_RS07825	COG1418	mRNA catabolic process
BACHE_RS07865	COG1595	DNA-templated transcription, initiation
BACHE_RS07875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BACHE_RS07880	COG2832	Protein of unknown function (DUF454)
BACHE_RS07885	COG0351	phosphomethylpyrimidine kinase
BACHE_RS07895	COG0602	queuosine metabolic process
BACHE_RS07930	COG0612	Peptidase, M16
BACHE_RS07945	COG4771	TonB-dependent receptor
BACHE_RS07965	COG1388	LysM domain
BACHE_RS07965	COG0741	lytic transglycosylase activity
BACHE_RS07985	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BACHE_RS08005	COG0564	pseudouridine synthase activity
BACHE_RS08025	COG0590	tRNA wobble adenosine to inosine editing
BACHE_RS08030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BACHE_RS08045	COG3119	arylsulfatase activity
BACHE_RS08050	COG3292	Two component regulator propeller
BACHE_RS08050	COG2205	protein histidine kinase activity
BACHE_RS08050	COG0745	RESPONSE REGULATOR receiver
BACHE_RS08065	COG4771	TonB-dependent receptor
BACHE_RS08070	COG0702	epimerase
BACHE_RS08075	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACHE_RS08085	COG3119	arylsulfatase activity
BACHE_RS08095	COG1940	carbohydrate kinase activity
BACHE_RS08110	COG3119	arylsulfatase activity
BACHE_RS08110	COG3408	Glycogen debranching enzyme
BACHE_RS08160	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BACHE_RS08170	COG0732	type I restriction modification DNA specificity domain
BACHE_RS08175	COG5290	Psort location Cytoplasmic, score
BACHE_RS08190	COG2184	nucleotidyltransferase activity
BACHE_RS08235	COG4974	Belongs to the 'phage' integrase family
BACHE_RS08245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BACHE_RS08250	COG0813	purine-nucleoside phosphorylase activity
BACHE_RS08255	COG4864	UPF0365 protein
BACHE_RS08270	COG0037	tRNA processing
BACHE_RS08280	COG1477	protein flavinylation
BACHE_RS08285	COG1971	Probably functions as a manganese efflux pump
BACHE_RS08300	COG0463	Glycosyl transferase, family 2
BACHE_RS08320	COG4771	TonB-dependent receptor
BACHE_RS08345	COG0148	phosphopyruvate hydratase activity
BACHE_RS08350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BACHE_RS08355	COG2205	protein histidine kinase activity
BACHE_RS08360	COG1082	Xylose isomerase domain protein TIM barrel
BACHE_RS08365	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BACHE_RS08370	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACHE_RS08375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BACHE_RS08380	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BACHE_RS08385	COG0254	rRNA binding
BACHE_RS08395	COG0191	fructose-bisphosphate aldolase activity
BACHE_RS08400	COG0366	Alpha amylase catalytic
BACHE_RS08410	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BACHE_RS08415	COG4770	biotin carboxylase activity
BACHE_RS08425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BACHE_RS08445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BACHE_RS08445	COG4651	solute:proton antiporter activity
BACHE_RS08450	COG0673	inositol 2-dehydrogenase activity
BACHE_RS08455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BACHE_RS08460	COG0193	aminoacyl-tRNA hydrolase activity
BACHE_RS08465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BACHE_RS08475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BACHE_RS08480	COG1862	Preprotein translocase
BACHE_RS08490	COG0237	dephospho-CoA kinase activity
BACHE_RS08500	COG0542	response to heat
BACHE_RS08510	COG0583	DNA-binding transcription factor activity
BACHE_RS08515	COG2855	membrane
BACHE_RS08535	COG1595	DNA-templated transcription, initiation
BACHE_RS08550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BACHE_RS08555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BACHE_RS08575	COG0534	Mate efflux family protein
BACHE_RS08580	COG0443	Heat shock 70 kDa protein
BACHE_RS08615	COG1629	transport
BACHE_RS08615	COG4206	TonB-dependent receptor
BACHE_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BACHE_RS08815	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BACHE_RS08820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BACHE_RS08850	COG1760	l-serine dehydratase
BACHE_RS08855	COG1193	negative regulation of DNA recombination
BACHE_RS08870	COG4974	Belongs to the 'phage' integrase family
BACHE_RS08880	COG1040	competence protein
BACHE_RS08980	COG1196	nuclear chromosome segregation
BACHE_RS09000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BACHE_RS09005	COG1882	Formate acetyltransferase
BACHE_RS09080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BACHE_RS09085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BACHE_RS09105	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BACHE_RS09105	COG1918	ferrous iron import across plasma membrane
BACHE_RS09130	COG0346	lactoylglutathione lyase activity
BACHE_RS09145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BACHE_RS09160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BACHE_RS09165	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BACHE_RS09170	COG0148	phosphopyruvate hydratase activity
BACHE_RS09195	COG4771	TonB-dependent receptor
BACHE_RS09220	COG1132	(ABC) transporter
BACHE_RS09230	COG2375	cellular response to nickel ion
BACHE_RS09230	COG1132	(ABC) transporter
BACHE_RS09255	COG1151	hydroxylamine reductase activity
BACHE_RS09290	COG4771	TonB-dependent receptor
BACHE_RS09320	COG0788	formyltetrahydrofolate deformylase activity
BACHE_RS09330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BACHE_RS09335	COG0107	imidazoleglycerol-phosphate synthase activity
BACHE_RS09340	COG0140	phosphoribosyl-ATP diphosphatase activity
BACHE_RS09340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BACHE_RS09345	COG2884	Cell division ATP-binding protein ftsE
BACHE_RS09350	COG0527	aspartate kinase activity
BACHE_RS09355	COG0019	diaminopimelate decarboxylase activity
BACHE_RS09365	COG0156	8-amino-7-oxononanoate synthase activity
BACHE_RS09385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BACHE_RS09385	COG0321	lipoyl(octanoyl) transferase activity
BACHE_RS09415	COG0497	DNA recombination
BACHE_RS09420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BACHE_RS09440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BACHE_RS09455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BACHE_RS09470	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BACHE_RS09475	COG0586	Pfam SNARE associated Golgi protein
BACHE_RS09485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BACHE_RS09490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BACHE_RS09495	COG0573	inorganic phosphate transmembrane transporter activity
BACHE_RS09500	COG0581	inorganic phosphate transmembrane transporter activity
BACHE_RS09505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BACHE_RS09510	COG0704	Plays a role in the regulation of phosphate uptake
BACHE_RS09565	COG3292	Two component regulator propeller
BACHE_RS09565	COG2205	protein histidine kinase activity
BACHE_RS09565	COG0745	RESPONSE REGULATOR receiver
BACHE_RS09585	COG4948	Mandelate Racemase Muconate Lactonizing
BACHE_RS09595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BACHE_RS09600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BACHE_RS09615	COG0446	pyridine nucleotide-disulphide oxidoreductase
BACHE_RS09620	COG0671	phosphoesterase, PA-phosphatase related
BACHE_RS09640	COG1086	Polysaccharide biosynthesis protein
BACHE_RS09645	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BACHE_RS09650	COG1083	cytidylyl-transferase
BACHE_RS09670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS09670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BACHE_RS09690	COG2089	acid synthase
BACHE_RS09695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BACHE_RS09760	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS09790	COG1215	transferase activity, transferring glycosyl groups
BACHE_RS09840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS09845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACHE_RS09855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BACHE_RS09875	COG1595	DNA-templated transcription, initiation
BACHE_RS09900	COG0686	Belongs to the AlaDH PNT family
BACHE_RS09905	COG0739	heme binding
BACHE_RS09915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BACHE_RS09955	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BACHE_RS09960	COG0295	cytidine deaminase activity
BACHE_RS09965	COG3951	Flagellar rod assembly protein muramidase FlgJ
BACHE_RS09965	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACHE_RS10010	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BACHE_RS10025	COG1269	ATP hydrolysis coupled proton transport
BACHE_RS10040	COG0058	SHG alpha-glucan phosphorylase activity
BACHE_RS10050	COG0716	FMN binding
BACHE_RS10060	COG0588	phosphoglycerate mutase activity
BACHE_RS10070	COG3610	response to peptide
BACHE_RS10075	COG2966	Psort location CytoplasmicMembrane, score
BACHE_RS10080	COG3610	response to peptide
BACHE_RS10090	COG1328	CTP reductase activity
BACHE_RS10100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS10105	COG0228	four-way junction DNA binding
BACHE_RS10115	COG1609	Transcriptional regulator
BACHE_RS10135	COG1442	glycosyl transferase family 8
BACHE_RS10135	COG1216	Glycosyl transferase, family 2
BACHE_RS10165	COG1216	Glycosyl transferase, family 2
BACHE_RS10165	COG1442	glycosyl transferase family 8
BACHE_RS10205	COG0745	RESPONSE REGULATOR receiver
BACHE_RS10215	COG0252	asparaginase activity
BACHE_RS10220	COG0159	tryptophan synthase activity
BACHE_RS10225	COG0135	phosphoribosylanthranilate isomerase activity
BACHE_RS10230	COG0134	indole-3-glycerol-phosphate synthase activity
BACHE_RS10235	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BACHE_RS10240	COG0512	Glutamine amidotransferase of anthranilate synthase
BACHE_RS10240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BACHE_RS10245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BACHE_RS10250	COG0133	tryptophan synthase activity
BACHE_RS10265	COG2223	nitrite transmembrane transporter activity
BACHE_RS10285	COG0004	ammonium transporteR
BACHE_RS10290	COG0347	Belongs to the P(II) protein family
BACHE_RS10300	COG0436	Aminotransferase
BACHE_RS10305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BACHE_RS10315	COG0577	efflux transmembrane transporter activity
BACHE_RS10315	COG1136	(ABC) transporter
BACHE_RS10325	COG1136	(ABC) transporter
BACHE_RS10330	COG0577	efflux transmembrane transporter activity
BACHE_RS10355	COG2205	protein histidine kinase activity
BACHE_RS10355	COG0784	Response regulator, receiver
BACHE_RS10365	COG0436	Aminotransferase
BACHE_RS10370	COG4591	ABC-type transport system involved in lipoprotein release permease component
BACHE_RS10375	COG1215	transferase activity, transferring glycosyl groups
BACHE_RS10385	COG2226	methyltransferase
BACHE_RS10400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BACHE_RS10400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BACHE_RS10410	COG0367	asparagine synthase
BACHE_RS10420	COG0070	glutamate synthase
BACHE_RS10420	COG0067	glutamate synthase
BACHE_RS10420	COG0069	glutamate synthase activity
BACHE_RS10425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BACHE_RS10430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BACHE_RS10435	COG0505	Belongs to the CarA family
BACHE_RS10440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BACHE_RS10450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BACHE_RS10455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS10460	COG2207	Transcriptional regulator
BACHE_RS10460	COG1609	Transcriptional regulator
BACHE_RS10530	COG1216	Glycosyl transferase, family 2
BACHE_RS10555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BACHE_RS10560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BACHE_RS10570	COG0556	nucleotide-excision repair
BACHE_RS10575	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BACHE_RS10605	COG1388	LysM domain
BACHE_RS10605	COG3942	CHAP domain
BACHE_RS10610	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BACHE_RS10615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BACHE_RS10635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BACHE_RS10645	COG1160	GTP binding
BACHE_RS10650	COG1695	Transcriptional regulator
BACHE_RS10675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BACHE_RS10700	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BACHE_RS10705	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS10735	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BACHE_RS10745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS10750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACHE_RS10765	COG1022	Amp-dependent synthetase and ligase
BACHE_RS10770	COG3263	regulation of cellular component size
BACHE_RS10775	COG2205	protein histidine kinase activity
BACHE_RS10800	COG1136	(ABC) transporter
BACHE_RS10800	COG0577	efflux transmembrane transporter activity
BACHE_RS10815	COG0534	Mate efflux family protein
BACHE_RS10820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACHE_RS10825	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BACHE_RS10835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BACHE_RS10840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BACHE_RS10870	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BACHE_RS10875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BACHE_RS10880	COG0305	Participates in initiation and elongation during chromosome replication
BACHE_RS10885	COG2207	Transcriptional regulator
BACHE_RS10905	COG0657	acetylesterase activity
BACHE_RS10905	COG2755	lipolytic protein G-D-S-L family
BACHE_RS10930	COG3059	membrane
BACHE_RS10935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BACHE_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BACHE_RS10950	COG1120	ATPase activity
BACHE_RS10960	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BACHE_RS11010	COG4772	TonB-dependent receptor
BACHE_RS11020	COG4771	TonB-dependent receptor
BACHE_RS11025	COG0439	Biotin carboxylase
BACHE_RS11035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BACHE_RS11045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BACHE_RS11055	COG1797	cobyrinic acid a,c-diamide synthase activity
BACHE_RS11085	COG1216	Glycosyl transferase, family 2
BACHE_RS11095	COG0438	transferase activity, transferring glycosyl groups
BACHE_RS11130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS11135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACHE_RS11140	COG2096	Adenosyltransferase
BACHE_RS11145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BACHE_RS11160	COG1492	cobalamin metabolic process
BACHE_RS11170	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BACHE_RS11175	COG2205	protein histidine kinase activity
BACHE_RS11180	COG2202	Pas domain
BACHE_RS11180	COG2205	protein histidine kinase activity
BACHE_RS11190	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BACHE_RS11195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BACHE_RS11210	COG0442	prolyl-tRNA aminoacylation
BACHE_RS11230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BACHE_RS11235	COG0248	Ppx GppA phosphatase
BACHE_RS11245	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BACHE_RS11250	COG1546	Belongs to the CinA family
BACHE_RS11250	COG1058	Belongs to the CinA family
BACHE_RS11255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BACHE_RS11260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BACHE_RS11265	COG0552	protein localization to endoplasmic reticulum
BACHE_RS11270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACHE_RS11285	COG0714	Associated with various cellular activities
BACHE_RS11300	COG2304	oxidoreductase activity
BACHE_RS11345	COG0542	response to heat
BACHE_RS11350	COG0326	Molecular chaperone. Has ATPase activity
BACHE_RS11355	COG1752	Esterase of the alpha-beta hydrolase superfamily
BACHE_RS11375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BACHE_RS11380	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BACHE_RS11385	COG0336	Belongs to the RNA methyltransferase TrmD family
BACHE_RS11390	COG0167	dihydroorotate dehydrogenase activity
BACHE_RS11395	COG0543	2 iron, 2 sulfur cluster binding
BACHE_RS11410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BACHE_RS11420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BACHE_RS11440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BACHE_RS11450	COG0390	transport system, permease component
BACHE_RS11455	COG1132	(ABC) transporter
BACHE_RS11480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BACHE_RS11485	COG1597	lipid kinase activity
BACHE_RS11490	COG0156	8-amino-7-oxononanoate synthase activity
BACHE_RS11505	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BACHE_RS11510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BACHE_RS11515	COG0343	queuine tRNA-ribosyltransferase activity
BACHE_RS11530	COG0560	Phosphoserine phosphatase
BACHE_RS11530	COG3830	Belongs to the UPF0237 family
BACHE_RS11535	COG0513	Belongs to the DEAD box helicase family
BACHE_RS11565	COG1904	glucuronate isomerase
BACHE_RS11570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BACHE_RS11585	COG2194	sulfuric ester hydrolase activity
BACHE_RS11610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BACHE_RS11625	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BACHE_RS11635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BACHE_RS11645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BACHE_RS11645	COG3153	acetyltransferase
BACHE_RS11650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BACHE_RS11655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BACHE_RS11665	COG2814	Major facilitator Superfamily
BACHE_RS11665	COG0477	Major facilitator Superfamily
BACHE_RS11670	COG2115	Belongs to the xylose isomerase family
BACHE_RS11685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BACHE_RS11695	COG0352	thiamine-phosphate diphosphorylase activity
BACHE_RS11700	COG2022	thiamine diphosphate biosynthetic process
BACHE_RS11705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BACHE_RS11710	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BACHE_RS11715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BACHE_RS11725	COG0351	phosphomethylpyrimidine kinase
BACHE_RS11755	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BACHE_RS11780	COG4413	Urea transporter
BACHE_RS11810	COG4771	TonB-dependent receptor
BACHE_RS11830	COG0358	DNA primase activity
BACHE_RS11915	COG2003	Belongs to the UPF0758 family
BACHE_RS12070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BACHE_RS12085	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BACHE_RS12095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BACHE_RS12100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BACHE_RS12110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BACHE_RS12125	COG0673	inositol 2-dehydrogenase activity
BACHE_RS12150	COG2244	polysaccharide biosynthetic process
BACHE_RS12160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BACHE_RS12200	COG0702	epimerase
BACHE_RS12205	COG1629	transport
BACHE_RS12220	COG0540	Belongs to the ATCase OTCase family
BACHE_RS12225	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BACHE_RS12230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BACHE_RS12240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BACHE_RS12245	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BACHE_RS12285	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BACHE_RS12290	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BACHE_RS12295	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BACHE_RS12300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BACHE_RS12305	COG0356	it plays a direct role in the translocation of protons across the membrane
BACHE_RS12315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BACHE_RS12330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BACHE_RS12335	COG4657	Part of a membrane complex involved in electron transport
BACHE_RS12340	COG4660	Part of a membrane complex involved in electron transport
BACHE_RS12345	COG4659	FMN binding
BACHE_RS12350	COG4658	electron transport chain
BACHE_RS12355	COG4656	Part of a membrane complex involved in electron transport
BACHE_RS12375	COG0504	CTP synthase activity
BACHE_RS12385	COG0534	Mate efflux family protein
BACHE_RS12390	COG1506	peptidase
BACHE_RS12390	COG0823	Involved in the tonB-independent uptake of proteins
BACHE_RS12395	COG1074	ATP-dependent DNA helicase activity
BACHE_RS12415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS12420	COG1475	DNA binding
BACHE_RS12425	COG3969	phosphoadenosine phosphosulfate
BACHE_RS12435	COG0738	Major facilitator superfamily
BACHE_RS12470	COG1475	DNA binding
BACHE_RS12495	COG2207	Transcriptional regulator
BACHE_RS12500	COG4584	PFAM Integrase catalytic
BACHE_RS12505	COG1484	DNA-dependent DNA replication
BACHE_RS12570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BACHE_RS12630	COG0352	thiamine-phosphate diphosphorylase activity
BACHE_RS12635	COG2205	protein histidine kinase activity
BACHE_RS12635	COG0784	Response regulator, receiver
BACHE_RS12635	COG5002	protein histidine kinase activity
BACHE_RS12640	COG0574	Belongs to the PEP-utilizing enzyme family
BACHE_RS12640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BACHE_RS12645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BACHE_RS12650	COG0564	pseudouridine synthase activity
BACHE_RS12665	COG4804	nuclease activity
BACHE_RS12695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BACHE_RS12715	COG0420	3'-5' exonuclease activity
BACHE_RS12725	COG0024	Methionine aminopeptidase
BACHE_RS12735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BACHE_RS12740	COG2233	PERMEase
BACHE_RS12745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BACHE_RS12750	COG0481	GTPase activity
BACHE_RS12770	COG0708	Exodeoxyribonuclease III
BACHE_RS12785	COG0217	transcriptional regulatory protein
BACHE_RS12815	COG1215	transferase activity, transferring glycosyl groups
BACHE_RS12835	COG1216	Glycosyl transferase, family 2
BACHE_RS12860	COG2244	polysaccharide biosynthetic process
BACHE_RS12870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BACHE_RS12910	COG0357	Ribosomal RNA small subunit methyltransferase G
BACHE_RS12915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BACHE_RS12920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BACHE_RS12920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BACHE_RS12925	COG1272	protein, Hemolysin III
BACHE_RS12935	COG1739	Uncharacterized protein family UPF0029
BACHE_RS12945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BACHE_RS12950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BACHE_RS12955	COG0513	Belongs to the DEAD box helicase family
BACHE_RS12965	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BACHE_RS12975	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BACHE_RS12980	COG1805	sodium ion transport
BACHE_RS12985	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BACHE_RS13015	COG0612	Peptidase, M16
BACHE_RS13035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BACHE_RS13040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BACHE_RS13055	COG1864	DNA RNA non-specific endonuclease
BACHE_RS13055	COG3591	Belongs to the peptidase S1B family
BACHE_RS13065	COG4206	TonB-dependent receptor
BACHE_RS13065	COG1629	transport
BACHE_RS13070	COG0488	(ABC) transporter
BACHE_RS13140	COG4974	Belongs to the 'phage' integrase family
BACHE_RS13145	COG4974	Belongs to the 'phage' integrase family
BACHE_RS13305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BACHE_RS13325	COG3345	alpha-galactosidase
BACHE_RS13330	COG3842	ATPase activity
BACHE_RS13335	COG1176	ABC-type spermidine putrescine transport system, permease component I
BACHE_RS13340	COG1177	transmembrane transport
BACHE_RS13350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BACHE_RS13360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BACHE_RS13385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACHE_RS13390	COG1136	(ABC) transporter
BACHE_RS13395	COG1136	(ABC) transporter
BACHE_RS13395	COG0577	efflux transmembrane transporter activity
BACHE_RS13405	COG3279	Response regulator of the LytR AlgR family
BACHE_RS13420	COG0363	glucosamine-6-phosphate deaminase activity
BACHE_RS13425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BACHE_RS13430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BACHE_RS13435	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BACHE_RS13455	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BACHE_RS13460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACHE_RS13475	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BACHE_RS13485	COG0306	phosphate transporter
BACHE_RS13495	COG0586	Pfam SNARE associated Golgi protein
BACHE_RS13530	COG0534	Mate efflux family protein
BACHE_RS13540	COG4948	Mandelate Racemase Muconate Lactonizing
BACHE_RS13545	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BACHE_RS13550	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BACHE_RS13555	COG1169	isochorismate synthase
BACHE_RS13610	COG4977	sequence-specific DNA binding
BACHE_RS13610	COG1917	Cupin 2, conserved barrel domain protein
BACHE_RS13615	COG4771	TonB-dependent receptor
BACHE_RS13625	COG0737	Belongs to the 5'-nucleotidase family
BACHE_RS13630	COG2205	protein histidine kinase activity
BACHE_RS13630	COG2202	Pas domain
BACHE_RS13635	COG2183	response to ionizing radiation
BACHE_RS13650	COG0488	(ABC) transporter
BACHE_RS13655	COG4771	TonB-dependent receptor
BACHE_RS13660	COG2814	Major facilitator Superfamily
BACHE_RS13665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BACHE_RS13670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BACHE_RS13680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BACHE_RS13685	COG0484	heat shock protein binding
BACHE_RS13725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS13745	COG0702	epimerase
BACHE_RS13750	COG4771	TonB-dependent receptor
BACHE_RS13765	COG2271	Major facilitator Superfamily
BACHE_RS13770	COG2731	YhcH YjgK YiaL family protein
BACHE_RS13780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS13785	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS13790	COG3250	beta-galactosidase activity
BACHE_RS13795	COG1940	carbohydrate kinase activity
BACHE_RS13965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BACHE_RS13975	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BACHE_RS13975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BACHE_RS13975	COG1013	pyruvate-flavodoxin oxidoreductase activity
BACHE_RS13975	COG0674	pyruvate-flavodoxin oxidoreductase activity
BACHE_RS13980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BACHE_RS13985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BACHE_RS13990	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BACHE_RS13995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BACHE_RS14000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BACHE_RS14010	COG0242	peptide deformylase activity
BACHE_RS14015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BACHE_RS14040	COG4974	Belongs to the 'phage' integrase family
BACHE_RS14075	COG2895	sulfate adenylyltransferase (ATP) activity
BACHE_RS14080	COG0175	sulfate reduction
BACHE_RS14085	COG0529	Catalyzes the synthesis of activated sulfate
BACHE_RS14090	COG3273	potassium ion transport
BACHE_RS14090	COG0471	metal ion transport
BACHE_RS14095	COG1218	3'(2'),5'-bisphosphate nucleotidase
BACHE_RS14105	COG0513	Belongs to the DEAD box helicase family
BACHE_RS14125	COG1482	cell wall glycoprotein biosynthetic process
BACHE_RS14140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BACHE_RS14145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BACHE_RS14150	COG0698	ribose 5-phosphate isomerase
BACHE_RS14190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BACHE_RS14195	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BACHE_RS14195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BACHE_RS14205	COG1592	Rubrerythrin
BACHE_RS14205	COG1773	rubredoxin
BACHE_RS14240	COG2264	protein methyltransferase activity
BACHE_RS14250	COG0577	efflux transmembrane transporter activity
BACHE_RS14265	COG0724	RNA recognition motif
BACHE_RS14280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BACHE_RS14305	COG0363	glucosamine-6-phosphate deaminase activity
BACHE_RS14325	COG1032	radical SAM domain protein
BACHE_RS14330	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BACHE_RS14350	COG0667	Aldo Keto reductase
BACHE_RS14375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BACHE_RS14380	COG0463	Glycosyl transferase, family 2
BACHE_RS14390	COG0646	methionine synthase
BACHE_RS14390	COG1410	methionine synthase
BACHE_RS14405	COG1408	metallophosphoesterase
BACHE_RS14410	COG5434	Belongs to the glycosyl hydrolase 28 family
BACHE_RS14445	COG1629	transport
BACHE_RS14445	COG4206	TonB-dependent receptor
BACHE_RS14470	COG0641	radical SAM
BACHE_RS14475	COG3591	Belongs to the peptidase S1B family
BACHE_RS14480	COG3591	Belongs to the peptidase S1B family
BACHE_RS14500	COG0488	(ABC) transporter
BACHE_RS14515	COG0745	RESPONSE REGULATOR receiver
BACHE_RS14520	COG5002	protein histidine kinase activity
BACHE_RS14535	COG0629	single-stranded DNA binding
BACHE_RS14540	COG1194	a g-specific adenine glycosylase
BACHE_RS14545	COG0776	regulation of translation
BACHE_RS14550	COG1530	ribonuclease E activity
BACHE_RS14560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACHE_RS14565	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BACHE_RS14600	COG2244	polysaccharide biosynthetic process
BACHE_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
BACHE_RS14625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BACHE_RS14660	COG1979	alcohol dehydrogenase
BACHE_RS14670	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BACHE_RS14695	COG4191	Histidine kinase
BACHE_RS14700	COG2204	response regulator
BACHE_RS14710	COG0131	Imidazoleglycerol-phosphate dehydratase
BACHE_RS14715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BACHE_RS14720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BACHE_RS14725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BACHE_RS14735	COG0738	Major facilitator superfamily
BACHE_RS14745	COG1070	Carbohydrate kinase
BACHE_RS14755	COG1454	alcohol dehydrogenase
BACHE_RS14760	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BACHE_RS14770	COG2205	protein histidine kinase activity
BACHE_RS14770	COG2202	Pas domain
BACHE_RS14790	COG4232	protein-disulfide reductase activity
BACHE_RS14800	COG0572	uridine kinase
BACHE_RS14805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BACHE_RS14820	COG0646	methionine synthase
BACHE_RS14820	COG1410	methionine synthase
BACHE_RS14825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BACHE_RS14865	COG1454	alcohol dehydrogenase
BACHE_RS14870	COG2207	Transcriptional regulator
BACHE_RS14875	COG0655	NAD(P)H dehydrogenase (quinone) activity
BACHE_RS14885	COG0110	maltose O-acetyltransferase activity
BACHE_RS14910	COG0482	sulfurtransferase activity
BACHE_RS14935	COG2382	esterase
BACHE_RS14935	COG3507	Belongs to the glycosyl hydrolase 43 family
BACHE_RS14935	COG3693	PFAM glycoside hydrolase, family 10
BACHE_RS14940	COG1253	flavin adenine dinucleotide binding
BACHE_RS14960	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACHE_RS14970	COG0671	phosphoesterase, PA-phosphatase related
BACHE_RS14980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BACHE_RS14995	COG1119	ATPase activity
BACHE_RS15005	COG1523	belongs to the glycosyl hydrolase 13 family
BACHE_RS15010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BACHE_RS15030	COG1629	transport
BACHE_RS15040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BACHE_RS15050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BACHE_RS15055	COG0126	phosphoglycerate kinase activity
BACHE_RS15065	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BACHE_RS15070	COG0471	metal ion transport
BACHE_RS15080	COG0424	maF-like protein
BACHE_RS15085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BACHE_RS15100	COG0778	Nitroreductase
BACHE_RS15125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BACHE_RS15130	COG4206	TonB-dependent receptor
BACHE_RS15130	COG1629	transport
BACHE_RS15140	COG2205	protein histidine kinase activity
BACHE_RS15140	COG3292	Two component regulator propeller
BACHE_RS15140	COG0745	RESPONSE REGULATOR receiver
BACHE_RS15145	COG1609	Transcriptional regulator
BACHE_RS15155	COG1554	hydrolase, family 65, central catalytic
BACHE_RS15160	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BACHE_RS15180	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BACHE_RS15185	COG1518	maintenance of DNA repeat elements
BACHE_RS15230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BACHE_RS15245	COG1280	lysine exporter protein (LysE YggA)
BACHE_RS15255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BACHE_RS15255	COG0047	phosphoribosylformylglycinamidine synthase activity
BACHE_RS15260	COG3292	Two component regulator propeller
BACHE_RS15260	COG2205	protein histidine kinase activity
BACHE_RS15260	COG0745	RESPONSE REGULATOR receiver
BACHE_RS15260	COG2205	protein histidine kinase activity
BACHE_RS15260	COG3292	Two component regulator propeller
BACHE_RS15260	COG0745	RESPONSE REGULATOR receiver
BACHE_RS15275	COG1649	PFAM Uncharacterised BCR, COG1649
BACHE_RS15290	COG3119	arylsulfatase activity
BACHE_RS15305	COG1966	Carbon starvation protein
BACHE_RS15355	COG2205	protein histidine kinase activity
BACHE_RS15370	COG0667	Aldo Keto reductase
BACHE_RS15400	COG1621	beta-fructofuranosidase activity
BACHE_RS15410	COG4667	esterase of the alpha-beta hydrolase superfamily
BACHE_RS15420	COG0545	Peptidyl-prolyl cis-trans isomerase
BACHE_RS15425	COG3279	Response regulator of the LytR AlgR family
BACHE_RS15430	COG3275	phosphorelay sensor kinase activity
BACHE_RS15455	COG2086	electron transfer activity
BACHE_RS15460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BACHE_RS15475	COG0456	acetyltransferase
BACHE_RS15500	COG0484	heat shock protein binding
BACHE_RS15515	COG0459	protein refolding
BACHE_RS15520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BACHE_RS15535	COG0124	histidyl-tRNA synthetase
BACHE_RS15555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BACHE_RS15560	COG0735	belongs to the Fur family
BACHE_RS15580	COG0514	ATP-dependent DNA helicase (RecQ)
BACHE_RS15590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BACHE_RS15610	COG0066	3-isopropylmalate dehydratase activity
BACHE_RS15615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BACHE_RS15620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BACHE_RS15660	COG0616	signal peptide processing
BACHE_RS15665	COG1663	tetraacyldisaccharide 4'-kinase activity
BACHE_RS15670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BACHE_RS15675	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BACHE_RS15685	COG4974	Belongs to the 'phage' integrase family
BACHE_RS15750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BACHE_RS15775	COG2873	o-acetylhomoserine
BACHE_RS15785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BACHE_RS15810	COG5002	protein histidine kinase activity
BACHE_RS15820	COG0671	phosphoesterase, PA-phosphatase related
BACHE_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
BACHE_RS15845	COG0523	cobalamin synthesis protein
BACHE_RS15850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BACHE_RS15855	COG0194	GDP metabolic process
BACHE_RS15865	COG1214	PFAM Peptidase M22, glycoprotease
BACHE_RS15875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BACHE_RS15880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BACHE_RS15885	COG4942	peptidase
BACHE_RS15890	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BACHE_RS15895	COG0750	zinc metalloprotease
BACHE_RS15900	COG0673	inositol 2-dehydrogenase activity
BACHE_RS15905	COG0632	four-way junction helicase activity
BACHE_RS15915	COG0006	proline dipeptidase activity
BACHE_RS15940	COG4771	TonB-dependent receptor
BACHE_RS16030	COG0561	phosphatase activity
BACHE_RS16035	COG4771	TonB-dependent receptor
BACHE_RS16045	COG4771	TonB-dependent receptor
BACHE_RS16065	COG0363	glucosamine-6-phosphate deaminase activity
BACHE_RS16070	COG1940	carbohydrate kinase activity
BACHE_RS16125	COG1575	Belongs to the MenA family. Type 1 subfamily
BACHE_RS16135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BACHE_RS16140	COG5002	protein histidine kinase activity
BACHE_RS16150	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BACHE_RS16160	COG0617	tRNA 3'-terminal CCA addition
BACHE_RS16180	COG1629	transport
BACHE_RS16185	COG4771	TonB-dependent receptor
BACHE_RS16205	COG2204	response regulator
BACHE_RS16210	COG0488	(ABC) transporter
BACHE_RS16215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BACHE_RS16245	COG4771	TonB-dependent receptor
BACHE_RS16260	COG1595	DNA-templated transcription, initiation
BACHE_RS16275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BACHE_RS16280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BACHE_RS16285	COG1522	sequence-specific DNA binding
BACHE_RS16315	COG0811	peptide transport
BACHE_RS16325	COG0084	hydrolase, TatD family'
BACHE_RS16345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BACHE_RS16350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BACHE_RS16355	COG0205	6-phosphofructokinase activity
BACHE_RS16360	COG0372	Belongs to the citrate synthase family
BACHE_RS16375	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BACHE_RS16385	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BACHE_RS16395	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BACHE_RS16405	COG0440	acetolactate synthase activity
BACHE_RS16415	COG0129	dihydroxy-acid dehydratase activity
BACHE_RS16420	COG1047	Peptidyl-prolyl cis-trans
BACHE_RS16425	COG3681	Belongs to the UPF0597 family
BACHE_RS16460	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACHE_RS16460	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACHE_RS16465	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACHE_RS16470	COG2985	domain, Protein
BACHE_RS16470	COG0569	domain protein
BACHE_RS16485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BACHE_RS16490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BACHE_RS16495	COG0166	Belongs to the GPI family
BACHE_RS16500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACHE_RS16510	COG2502	aspartate--ammonia ligase
BACHE_RS16515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BACHE_RS16535	COG0463	Glycosyl transferase, family 2
BACHE_RS16555	COG0860	N-Acetylmuramoyl-L-alanine amidase
BACHE_RS16585	COG3279	Response regulator of the LytR AlgR family
BACHE_RS16650	COG2205	protein histidine kinase activity
BACHE_RS16675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BACHE_RS16715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACHE_RS16740	COG2169	Transcriptional regulator