locus-tag	class	description
DXK01_RS00010	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXK01_RS00010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXK01_RS00015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DXK01_RS00020	COG0569	domain protein
DXK01_RS00020	COG2985	domain, Protein
DXK01_RS00035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DXK01_RS00040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DXK01_RS00045	COG0166	Belongs to the GPI family
DXK01_RS00050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXK01_RS00075	COG2502	aspartate--ammonia ligase
DXK01_RS00080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DXK01_RS00095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DXK01_RS00105	COG0463	Glycosyl transferase, family 2
DXK01_RS00120	COG0860	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS00130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DXK01_RS00135	COG0778	Nitroreductase
DXK01_RS00145	COG1640	4-alpha-glucanotransferase
DXK01_RS00155	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DXK01_RS00210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXK01_RS00215	COG0318	PFAM AMP-dependent synthetase and ligase
DXK01_RS00230	COG0359	binds to the 23S rRNA
DXK01_RS00235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DXK01_RS00240	COG0360	Binds together with S18 to 16S ribosomal RNA
DXK01_RS00260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DXK01_RS00265	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DXK01_RS00290	COG2755	lipolytic protein G-D-S-L family
DXK01_RS00300	COG4206	TonB-dependent receptor
DXK01_RS00300	COG1629	transport
DXK01_RS00315	COG3292	Two component regulator propeller
DXK01_RS00315	COG2205	protein histidine kinase activity
DXK01_RS00315	COG0745	RESPONSE REGULATOR receiver
DXK01_RS00325	COG3250	beta-galactosidase activity
DXK01_RS00340	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS00380	COG0561	phosphatase activity
DXK01_RS00385	COG1629	transport
DXK01_RS00385	COG4206	TonB-dependent receptor
DXK01_RS00390	COG3292	Two component regulator propeller
DXK01_RS00390	COG2205	protein histidine kinase activity
DXK01_RS00390	COG0745	RESPONSE REGULATOR receiver
DXK01_RS00405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DXK01_RS00420	COG4771	TonB-dependent receptor
DXK01_RS00430	COG3292	Two component regulator propeller
DXK01_RS00430	COG2205	protein histidine kinase activity
DXK01_RS00430	COG0745	RESPONSE REGULATOR receiver
DXK01_RS00430	COG3292	Two component regulator propeller
DXK01_RS00430	COG2205	protein histidine kinase activity
DXK01_RS00430	COG0745	RESPONSE REGULATOR receiver
DXK01_RS00435	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS00460	COG4206	TonB-dependent receptor
DXK01_RS00460	COG1629	transport
DXK01_RS00525	COG3275	phosphorelay sensor kinase activity
DXK01_RS00555	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DXK01_RS00560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DXK01_RS00565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXK01_RS00575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DXK01_RS00585	COG3119	arylsulfatase activity
DXK01_RS00595	COG3292	Two component regulator propeller
DXK01_RS00595	COG0745	RESPONSE REGULATOR receiver
DXK01_RS00595	COG2205	protein histidine kinase activity
DXK01_RS00605	COG4771	TonB-dependent receptor
DXK01_RS00610	COG0702	epimerase
DXK01_RS00615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS00625	COG3119	arylsulfatase activity
DXK01_RS00635	COG1940	carbohydrate kinase activity
DXK01_RS00650	COG3119	arylsulfatase activity
DXK01_RS00650	COG3408	Glycogen debranching enzyme
DXK01_RS00745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DXK01_RS00760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DXK01_RS00770	COG0009	L-threonylcarbamoyladenylate synthase
DXK01_RS00785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DXK01_RS00790	COG0542	response to heat
DXK01_RS00795	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DXK01_RS00800	COG3022	response to hydroperoxide
DXK01_RS00805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DXK01_RS00805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DXK01_RS00810	COG0514	ATP-dependent DNA helicase (RecQ)
DXK01_RS00815	COG0501	Belongs to the peptidase M48B family
DXK01_RS00830	COG4771	TonB-dependent receptor
DXK01_RS00840	COG3069	C4-dicarboxylate transmembrane transporter activity
DXK01_RS00845	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DXK01_RS00870	COG0436	Aminotransferase
DXK01_RS00875	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DXK01_RS00885	COG0358	DNA primase activity
DXK01_RS00890	COG0302	gtp cyclohydrolase
DXK01_RS00900	COG0149	triose-phosphate isomerase activity
DXK01_RS00915	COG0739	heme binding
DXK01_RS00920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DXK01_RS00925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DXK01_RS00940	COG0848	biopolymer transport protein
DXK01_RS00945	COG0811	peptide transport
DXK01_RS00950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DXK01_RS00955	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DXK01_RS00960	COG0039	L-malate dehydrogenase activity
DXK01_RS00975	COG1132	(ABC) transporter
DXK01_RS01000	COG1132	(ABC) transporter
DXK01_RS01035	COG1132	(ABC) transporter
DXK01_RS01060	COG1132	(ABC) transporter
DXK01_RS01090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS01115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS01120	COG0673	inositol 2-dehydrogenase activity
DXK01_RS01125	COG3250	beta-galactosidase activity
DXK01_RS01130	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS01140	COG1629	transport
DXK01_RS01140	COG4206	TonB-dependent receptor
DXK01_RS01160	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DXK01_RS01165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DXK01_RS01170	COG0489	protein tyrosine kinase activity
DXK01_RS01175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DXK01_RS01180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXK01_RS01190	COG1570	exodeoxyribonuclease VII activity
DXK01_RS01200	COG0482	sulfurtransferase activity
DXK01_RS01205	COG2382	esterase
DXK01_RS01205	COG3693	PFAM glycoside hydrolase, family 10
DXK01_RS01235	COG0352	thiamine-phosphate diphosphorylase activity
DXK01_RS01240	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DXK01_RS01245	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
DXK01_RS01255	COG0352	thiamine-phosphate diphosphorylase activity
DXK01_RS01260	COG0351	phosphomethylpyrimidine kinase
DXK01_RS01265	COG0673	inositol 2-dehydrogenase activity
DXK01_RS01275	COG1408	metallophosphoesterase
DXK01_RS01280	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DXK01_RS01285	COG3119	arylsulfatase activity
DXK01_RS01295	COG1629	transport
DXK01_RS01315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DXK01_RS01320	COG0179	Fumarylacetoacetate (FAA) hydrolase
DXK01_RS01325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DXK01_RS01340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DXK01_RS01345	COG0052	Belongs to the universal ribosomal protein uS2 family
DXK01_RS01350	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DXK01_RS01355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DXK01_RS01370	COG0017	Asparaginyl-tRNA synthetase
DXK01_RS01375	COG1187	pseudouridine synthase activity
DXK01_RS01400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DXK01_RS01420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DXK01_RS01435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXK01_RS01445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DXK01_RS01450	COG0516	GMP reductase activity
DXK01_RS01450	COG0517	IMP dehydrogenase activity
DXK01_RS01455	COG0514	ATP-dependent DNA helicase (RecQ)
DXK01_RS01460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DXK01_RS01465	COG0740	serine-type endopeptidase activity
DXK01_RS01470	COG0544	peptidyl-prolyl cis-trans isomerase activity
DXK01_RS01475	COG0724	RNA recognition motif
DXK01_RS01485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DXK01_RS01490	COG1127	ABC transporter
DXK01_RS01495	COG2197	response regulator
DXK01_RS01500	COG4585	Histidine kinase
DXK01_RS01505	COG1160	GTP binding
DXK01_RS01510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DXK01_RS01515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXK01_RS01530	COG4191	Histidine kinase
DXK01_RS01560	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS01625	COG1752	Esterase of the alpha-beta hydrolase superfamily
DXK01_RS01640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DXK01_RS01645	COG2202	Pas domain
DXK01_RS01645	COG2205	protein histidine kinase activity
DXK01_RS01650	COG2205	protein histidine kinase activity
DXK01_RS01650	COG2202	Pas domain
DXK01_RS01665	COG0436	Aminotransferase
DXK01_RS01670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DXK01_RS01700	COG0681	Belongs to the peptidase S26 family
DXK01_RS01745	COG2081	HI0933 family
DXK01_RS01760	COG0793	Belongs to the peptidase S41A family
DXK01_RS01760	COG4946	Tricorn protease homolog
DXK01_RS01765	COG0745	RESPONSE REGULATOR receiver
DXK01_RS01765	COG3292	Two component regulator propeller
DXK01_RS01765	COG2205	protein histidine kinase activity
DXK01_RS01795	COG0702	epimerase
DXK01_RS01800	COG4206	TonB-dependent receptor
DXK01_RS01800	COG1629	transport
DXK01_RS01810	COG3177	Filamentation induced by cAMP protein fic
DXK01_RS01815	COG4948	Mandelate Racemase Muconate Lactonizing
DXK01_RS01835	COG5002	protein histidine kinase activity
DXK01_RS01840	COG2205	protein histidine kinase activity
DXK01_RS01850	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DXK01_RS01855	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DXK01_RS01860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DXK01_RS01875	COG2204	response regulator
DXK01_RS01885	COG2942	2-epimerase
DXK01_RS01890	COG2211	Major facilitator Superfamily
DXK01_RS01895	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DXK01_RS01900	COG4124	Belongs to the glycosyl hydrolase 26 family
DXK01_RS01905	COG0702	epimerase
DXK01_RS01910	COG4771	TonB-dependent receptor
DXK01_RS01925	COG5434	Belongs to the glycosyl hydrolase 28 family
DXK01_RS01940	COG0662	Cupin 2, conserved barrel domain protein
DXK01_RS01940	COG2207	Transcriptional regulator
DXK01_RS01945	COG0667	Aldo Keto reductase
DXK01_RS01960	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS01970	COG0737	Belongs to the 5'-nucleotidase family
DXK01_RS01990	COG3693	PFAM glycoside hydrolase, family 10
DXK01_RS01990	COG2382	esterase
DXK01_RS01995	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS02005	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS02015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS02025	COG0577	efflux transmembrane transporter activity
DXK01_RS02025	COG1136	(ABC) transporter
DXK01_RS02030	COG1136	(ABC) transporter
DXK01_RS02030	COG0577	efflux transmembrane transporter activity
DXK01_RS02035	COG1940	carbohydrate kinase activity
DXK01_RS02050	COG0335	large ribosomal subunit rRNA binding
DXK01_RS02060	COG2996	Protein conserved in bacteria
DXK01_RS02065	COG0039	L-malate dehydrogenase activity
DXK01_RS02095	COG3250	beta-galactosidase activity
DXK01_RS02110	COG0235	Class ii aldolase
DXK01_RS02120	COG4806	L-rhamnose isomerase
DXK01_RS02125	COG1070	Carbohydrate kinase
DXK01_RS02135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS02155	COG0137	argininosuccinate synthase activity
DXK01_RS02165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DXK01_RS02170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DXK01_RS02175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DXK01_RS02180	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS02180	COG1396	sequence-specific DNA binding
DXK01_RS02185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXK01_RS02205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS02220	COG3119	arylsulfatase activity
DXK01_RS02235	COG0702	epimerase
DXK01_RS02240	COG4771	TonB-dependent receptor
DXK01_RS02275	COG4584	PFAM Integrase catalytic
DXK01_RS02280	COG1484	DNA-dependent DNA replication
DXK01_RS02310	COG0165	Argininosuccinate lyase
DXK01_RS02320	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DXK01_RS02330	COG2890	protein-(glutamine-N5) methyltransferase activity
DXK01_RS02335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXK01_RS02335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DXK01_RS02350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DXK01_RS02370	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DXK01_RS02380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DXK01_RS02420	COG0702	epimerase
DXK01_RS02430	COG4771	TonB-dependent receptor
DXK01_RS02475	COG3250	beta-galactosidase activity
DXK01_RS02480	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS02485	COG3537	Alpha-1,2-mannosidase
DXK01_RS02535	COG1629	transport
DXK01_RS02550	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS02555	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS02575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DXK01_RS02590	COG0564	pseudouridine synthase activity
DXK01_RS02615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DXK01_RS02620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DXK01_RS02625	COG0463	Glycosyl transferase, family 2
DXK01_RS02625	COG1216	Glycosyl transferase, family 2
DXK01_RS02630	COG2003	Belongs to the UPF0758 family
DXK01_RS02640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DXK01_RS02655	COG1785	Belongs to the alkaline phosphatase family
DXK01_RS02660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DXK01_RS02665	COG0280	phosphate acetyltransferase
DXK01_RS02670	COG1380	Effector of murein hydrolase LrgA
DXK01_RS02675	COG1346	cytolysis
DXK01_RS02705	COG0312	modulator of DNA gyrase
DXK01_RS02710	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DXK01_RS02715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DXK01_RS02730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DXK01_RS02740	COG0733	neurotransmitter:sodium symporter activity
DXK01_RS02750	COG2205	protein histidine kinase activity
DXK01_RS02755	COG1136	(ABC) transporter
DXK01_RS02760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DXK01_RS02765	COG0589	response to stress
DXK01_RS02765	COG0475	glutathione-regulated potassium exporter activity
DXK01_RS02770	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DXK01_RS02780	COG0702	epimerase
DXK01_RS02785	COG1629	transport
DXK01_RS02785	COG4206	TonB-dependent receptor
DXK01_RS02795	COG4206	TonB-dependent receptor
DXK01_RS02795	COG1629	transport
DXK01_RS02810	COG1649	PFAM Uncharacterised BCR, COG1649
DXK01_RS02820	COG1629	transport
DXK01_RS02820	COG4206	TonB-dependent receptor
DXK01_RS02835	COG3876	Protein conserved in bacteria
DXK01_RS02840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DXK01_RS02855	COG1216	Glycosyl transferase, family 2
DXK01_RS02855	COG0463	Glycosyl transferase, family 2
DXK01_RS02870	COG2807	transmembrane transport
DXK01_RS02875	COG3876	Protein conserved in bacteria
DXK01_RS02895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DXK01_RS02910	COG0423	glycine-tRNA ligase activity
DXK01_RS02950	COG4771	TonB-dependent receptor
DXK01_RS02985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS03015	COG2954	triphosphatase activity
DXK01_RS03020	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DXK01_RS03025	COG0612	Peptidase, M16
DXK01_RS03035	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS03040	COG1022	Amp-dependent synthetase and ligase
DXK01_RS03050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DXK01_RS03055	COG4942	peptidase
DXK01_RS03070	COG0756	dUTP diphosphatase activity
DXK01_RS03115	COG3250	beta-galactosidase activity
DXK01_RS03120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS03125	COG3119	arylsulfatase activity
DXK01_RS03130	COG0702	epimerase
DXK01_RS03135	COG4771	TonB-dependent receptor
DXK01_RS03150	COG0745	RESPONSE REGULATOR receiver
DXK01_RS03150	COG3292	Two component regulator propeller
DXK01_RS03150	COG2205	protein histidine kinase activity
DXK01_RS03155	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS03160	COG3119	arylsulfatase activity
DXK01_RS03165	COG3250	beta-galactosidase activity
DXK01_RS03170	COG2001	Belongs to the MraZ family
DXK01_RS03190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DXK01_RS03195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXK01_RS03200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DXK01_RS03205	COG0772	Belongs to the SEDS family
DXK01_RS03210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DXK01_RS03215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DXK01_RS03225	COG0849	cell division
DXK01_RS03230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DXK01_RS03235	COG1610	YqeY-like protein
DXK01_RS03245	COG1381	Involved in DNA repair and RecF pathway recombination
DXK01_RS03255	COG0268	Binds directly to 16S ribosomal RNA
DXK01_RS03260	COG0187	DNA topoisomerase II activity
DXK01_RS03270	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DXK01_RS03285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DXK01_RS03295	COG1629	transport
DXK01_RS03295	COG4206	TonB-dependent receptor
DXK01_RS03310	COG2431	L-lysine efflux transmembrane transporter activity
DXK01_RS03320	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
DXK01_RS03320	COG3408	Glycogen debranching enzyme
DXK01_RS03325	COG5652	VanZ like family
DXK01_RS03330	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DXK01_RS03335	COG0745	RESPONSE REGULATOR receiver
DXK01_RS03335	COG3292	Two component regulator propeller
DXK01_RS03335	COG2205	protein histidine kinase activity
DXK01_RS03340	COG0702	epimerase
DXK01_RS03345	COG4771	TonB-dependent receptor
DXK01_RS03365	COG0393	Putative heavy-metal-binding
DXK01_RS03375	COG1253	flavin adenine dinucleotide binding
DXK01_RS03380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DXK01_RS03385	COG0719	Fe-S assembly protein
DXK01_RS03390	COG0396	ATPase activity
DXK01_RS03395	COG0719	Fe-S assembly protein
DXK01_RS03405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DXK01_RS03410	COG0195	Participates in both transcription termination and antitermination
DXK01_RS03415	COG0779	Required for maturation of 30S ribosomal subunits
DXK01_RS03420	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS03445	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS03485	COG1595	DNA-templated transcription, initiation
DXK01_RS03490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DXK01_RS03495	COG1166	arginine decarboxylase activity
DXK01_RS03500	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DXK01_RS03530	COG0328	RNA-DNA hybrid ribonuclease activity
DXK01_RS03530	COG3341	Caulimovirus viroplasmin
DXK01_RS03540	COG1132	(ABC) transporter
DXK01_RS03545	COG1368	sulfuric ester hydrolase activity
DXK01_RS03565	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS03575	COG1216	Glycosyl transferase, family 2
DXK01_RS03580	COG1442	glycosyl transferase family 8
DXK01_RS03600	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS03620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXK01_RS03625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DXK01_RS03630	COG0571	ribonuclease III activity
DXK01_RS03635	COG0205	6-phosphofructokinase activity
DXK01_RS03655	COG0215	cysteine-tRNA ligase activity
DXK01_RS03660	COG3119	arylsulfatase activity
DXK01_RS03665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS03685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS03695	COG1538	Outer membrane efflux protein
DXK01_RS03700	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DXK01_RS03720	COG3292	Two component regulator propeller
DXK01_RS03720	COG0745	RESPONSE REGULATOR receiver
DXK01_RS03720	COG3292	Two component regulator propeller
DXK01_RS03720	COG2205	protein histidine kinase activity
DXK01_RS03720	COG2205	protein histidine kinase activity
DXK01_RS03720	COG0745	RESPONSE REGULATOR receiver
DXK01_RS03725	COG3119	arylsulfatase activity
DXK01_RS03730	COG4771	TonB-dependent receptor
DXK01_RS03735	COG0702	epimerase
DXK01_RS03745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXK01_RS03750	COG3119	arylsulfatase activity
DXK01_RS03810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DXK01_RS03820	COG0681	Belongs to the peptidase S26 family
DXK01_RS03835	COG4771	TonB-dependent receptor
DXK01_RS03860	COG3250	beta-galactosidase activity
DXK01_RS03865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS03930	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS03935	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DXK01_RS03955	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DXK01_RS03975	COG0612	Peptidase, M16
DXK01_RS03985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXK01_RS03995	COG0513	Belongs to the DEAD box helicase family
DXK01_RS04000	COG0783	Belongs to the Dps family
DXK01_RS04005	COG0583	DNA-binding transcription factor activity
DXK01_RS04015	COG3634	alkyl hydroperoxide reductase activity
DXK01_RS04030	COG3591	Belongs to the peptidase S1B family
DXK01_RS04045	COG2255	four-way junction helicase activity
DXK01_RS04060	COG0784	Response regulator, receiver
DXK01_RS04060	COG5002	protein histidine kinase activity
DXK01_RS04070	COG2715	membrane protein required for spore maturation
DXK01_RS04075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DXK01_RS04085	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS04090	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS04095	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DXK01_RS04100	COG1629	transport
DXK01_RS04130	COG3250	beta-galactosidase activity
DXK01_RS04140	COG2205	protein histidine kinase activity
DXK01_RS04140	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04140	COG3292	Two component regulator propeller
DXK01_RS04145	COG3119	arylsulfatase activity
DXK01_RS04145	COG3408	Glycogen debranching enzyme
DXK01_RS04155	COG2017	converts alpha-aldose to the beta-anomer
DXK01_RS04170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DXK01_RS04175	COG1629	transport
DXK01_RS04175	COG4206	TonB-dependent receptor
DXK01_RS04200	COG0673	inositol 2-dehydrogenase activity
DXK01_RS04210	COG0673	inositol 2-dehydrogenase activity
DXK01_RS04215	COG2205	protein histidine kinase activity
DXK01_RS04215	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04215	COG3292	Two component regulator propeller
DXK01_RS04220	COG3250	beta-galactosidase activity
DXK01_RS04265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DXK01_RS04270	COG0322	excinuclease ABC activity
DXK01_RS04275	COG1490	D-aminoacyl-tRNA deacylase activity
DXK01_RS04280	COG1694	Mazg nucleotide pyrophosphohydrolase
DXK01_RS04285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DXK01_RS04290	COG0142	geranyltranstransferase activity
DXK01_RS04295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXK01_RS04295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DXK01_RS04320	COG0012	GTP binding
DXK01_RS04340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DXK01_RS04345	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DXK01_RS04355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXK01_RS04365	COG4771	TonB-dependent receptor
DXK01_RS04370	COG0702	epimerase
DXK01_RS04430	COG4948	Mandelate Racemase Muconate Lactonizing
DXK01_RS04440	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04440	COG2205	protein histidine kinase activity
DXK01_RS04440	COG3292	Two component regulator propeller
DXK01_RS04445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DXK01_RS04470	COG3250	beta-galactosidase activity
DXK01_RS04480	COG0702	epimerase
DXK01_RS04485	COG1629	transport
DXK01_RS04490	COG3292	Two component regulator propeller
DXK01_RS04490	COG2205	protein histidine kinase activity
DXK01_RS04490	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04565	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04580	COG0784	Response regulator, receiver
DXK01_RS04580	COG2198	Histidine kinase
DXK01_RS04580	COG5002	protein histidine kinase activity
DXK01_RS04590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXK01_RS04605	COG1704	LemA family
DXK01_RS04615	COG5002	protein histidine kinase activity
DXK01_RS04640	COG4771	TonB-dependent receptor
DXK01_RS04645	COG3119	arylsulfatase activity
DXK01_RS04655	COG0738	Major facilitator superfamily
DXK01_RS04670	COG1609	Transcriptional regulator
DXK01_RS04680	COG1069	ribulokinase activity
DXK01_RS04695	COG4771	TonB-dependent receptor
DXK01_RS04715	COG0697	spore germination
DXK01_RS04725	COG0495	leucyl-tRNA aminoacylation
DXK01_RS04730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXK01_RS04735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DXK01_RS04750	COG0673	inositol 2-dehydrogenase activity
DXK01_RS04765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DXK01_RS04785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DXK01_RS04785	COG0731	radical SAM domain protein
DXK01_RS04795	COG0659	secondary active sulfate transmembrane transporter activity
DXK01_RS04800	COG2205	protein histidine kinase activity
DXK01_RS04800	COG3292	Two component regulator propeller
DXK01_RS04800	COG0745	RESPONSE REGULATOR receiver
DXK01_RS04810	COG1629	transport
DXK01_RS04815	COG0561	phosphatase activity
DXK01_RS04835	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS04840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS04855	COG2315	Protein conserved in bacteria
DXK01_RS04920	COG0681	Belongs to the peptidase S26 family
DXK01_RS04955	COG3250	beta-galactosidase activity
DXK01_RS04960	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS04975	COG3693	PFAM glycoside hydrolase, family 10
DXK01_RS04975	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS04975	COG2382	esterase
DXK01_RS04985	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS04990	COG3250	beta-galactosidase activity
DXK01_RS04995	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS05000	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05005	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05010	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS05015	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05020	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS05040	COG1592	Rubrerythrin
DXK01_RS05115	COG0427	acetyl-CoA hydrolase
DXK01_RS05125	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXK01_RS05160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS05200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DXK01_RS05205	COG2177	Part of the ABC transporter FtsEX involved in
DXK01_RS05215	COG1968	undecaprenyl-diphosphatase activity
DXK01_RS05220	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DXK01_RS05225	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DXK01_RS05230	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DXK01_RS05240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DXK01_RS05260	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS05275	COG2382	esterase
DXK01_RS05280	COG2382	esterase
DXK01_RS05290	COG4771	TonB-dependent receptor
DXK01_RS05310	COG2382	esterase
DXK01_RS05350	COG1611	Belongs to the LOG family
DXK01_RS05365	COG0594	ribonuclease P activity
DXK01_RS05370	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DXK01_RS05380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DXK01_RS05390	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DXK01_RS05395	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS05400	COG4677	pectinesterase activity
DXK01_RS05430	COG1238	metal cluster binding
DXK01_RS05445	COG1506	peptidase
DXK01_RS05445	COG0823	Involved in the tonB-independent uptake of proteins
DXK01_RS05455	COG0116	Belongs to the methyltransferase superfamily
DXK01_RS05460	COG1045	serine acetyltransferase
DXK01_RS05465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXK01_RS05525	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS05565	COG1629	transport
DXK01_RS05570	COG0745	RESPONSE REGULATOR receiver
DXK01_RS05570	COG2205	protein histidine kinase activity
DXK01_RS05570	COG3292	Two component regulator propeller
DXK01_RS05575	COG0557	exoribonuclease II activity
DXK01_RS05580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DXK01_RS05595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DXK01_RS05605	COG0826	peptidase U32
DXK01_RS05625	COG3250	beta-galactosidase activity
DXK01_RS05665	COG5002	protein histidine kinase activity
DXK01_RS05670	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DXK01_RS05675	COG1053	succinate dehydrogenase
DXK01_RS05690	COG0671	phosphoesterase, PA-phosphatase related
DXK01_RS05695	COG0793	Belongs to the peptidase S41A family
DXK01_RS05700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DXK01_RS05745	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS05765	COG1629	transport
DXK01_RS05775	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS05795	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05800	COG3940	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05815	COG2205	protein histidine kinase activity
DXK01_RS05815	COG3292	Two component regulator propeller
DXK01_RS05815	COG0745	RESPONSE REGULATOR receiver
DXK01_RS05840	COG4206	TonB-dependent receptor
DXK01_RS05840	COG1629	transport
DXK01_RS05845	COG0702	epimerase
DXK01_RS05865	COG3940	Belongs to the glycosyl hydrolase 43 family
DXK01_RS05885	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DXK01_RS05890	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS05950	COG2268	Band 7 protein
DXK01_RS05955	COG3279	Response regulator of the LytR AlgR family
DXK01_RS05965	COG0745	RESPONSE REGULATOR receiver
DXK01_RS05965	COG3292	Two component regulator propeller
DXK01_RS05965	COG2205	protein histidine kinase activity
DXK01_RS05965	COG3292	Two component regulator propeller
DXK01_RS05965	COG2205	protein histidine kinase activity
DXK01_RS05965	COG0745	RESPONSE REGULATOR receiver
DXK01_RS05985	COG4771	TonB-dependent receptor
DXK01_RS06005	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS06010	COG3119	arylsulfatase activity
DXK01_RS06020	COG3119	arylsulfatase activity
DXK01_RS06085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DXK01_RS06095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DXK01_RS06145	COG1522	sequence-specific DNA binding
DXK01_RS06150	COG0545	Peptidyl-prolyl cis-trans isomerase
DXK01_RS06155	COG0545	Peptidyl-prolyl cis-trans isomerase
DXK01_RS06160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DXK01_RS06180	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS06200	COG2089	acid synthase
DXK01_RS06205	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DXK01_RS06210	COG1216	Glycosyl transferase, family 2
DXK01_RS06225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXK01_RS06225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXK01_RS06230	COG3594	Acyltransferase
DXK01_RS06270	COG0745	RESPONSE REGULATOR receiver
DXK01_RS06270	COG2205	protein histidine kinase activity
DXK01_RS06270	COG3292	Two component regulator propeller
DXK01_RS06285	COG3537	Alpha-1,2-mannosidase
DXK01_RS06325	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS06365	COG0702	epimerase
DXK01_RS06370	COG1629	transport
DXK01_RS06370	COG4206	TonB-dependent receptor
DXK01_RS06375	COG0606	chelatase, subunit chli
DXK01_RS06390	COG4974	Belongs to the 'phage' integrase family
DXK01_RS06395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DXK01_RS06410	COG2202	Pas domain
DXK01_RS06410	COG2205	protein histidine kinase activity
DXK01_RS06415	COG0784	Response regulator, receiver
DXK01_RS06415	COG2198	Histidine kinase
DXK01_RS06415	COG2205	protein histidine kinase activity
DXK01_RS06420	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DXK01_RS06425	COG4591	ABC-type transport system involved in lipoprotein release permease component
DXK01_RS06430	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS06435	COG3250	beta-galactosidase activity
DXK01_RS06450	COG3250	beta-galactosidase activity
DXK01_RS06460	COG3250	beta-galactosidase activity
DXK01_RS06470	COG0561	phosphatase activity
DXK01_RS06475	COG4771	TonB-dependent receptor
DXK01_RS06485	COG0457	Tetratricopeptide repeat
DXK01_RS06490	COG2814	Major facilitator Superfamily
DXK01_RS06490	COG0477	Major facilitator Superfamily
DXK01_RS06510	COG4999	Histidine kinase
DXK01_RS06510	COG3850	Histidine kinase
DXK01_RS06510	COG3437	response regulator, receiver
DXK01_RS06510	COG2205	protein histidine kinase activity
DXK01_RS06515	COG0318	PFAM AMP-dependent synthetase and ligase
DXK01_RS06530	COG1373	ATPase (AAA superfamily
DXK01_RS06535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DXK01_RS06540	COG1217	gtp-binding protein TYPA
DXK01_RS06550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DXK01_RS06555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DXK01_RS06565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DXK01_RS06585	COG5002	protein histidine kinase activity
DXK01_RS06590	COG1012	belongs to the aldehyde dehydrogenase family
DXK01_RS06600	COG1013	pyruvate-flavodoxin oxidoreductase activity
DXK01_RS06605	COG0674	pyruvate-flavodoxin oxidoreductase activity
DXK01_RS06605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DXK01_RS06660	COG3723	Recombinational DNA repair protein, rece pathway
DXK01_RS07005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DXK01_RS07010	COG0339	signal peptide processing
DXK01_RS07035	COG0018	arginyl-trna synthetase
DXK01_RS07055	COG2816	NAD+ diphosphatase activity
DXK01_RS07070	COG2176	DNA-directed DNA polymerase activity
DXK01_RS07095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXK01_RS07100	COG0793	Belongs to the peptidase S41A family
DXK01_RS07110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DXK01_RS07115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DXK01_RS07135	COG0006	proline dipeptidase activity
DXK01_RS07155	COG2311	Membrane
DXK01_RS07210	COG2205	protein histidine kinase activity
DXK01_RS07220	COG1283	sodium-dependent phosphate transmembrane transporter activity
DXK01_RS07225	COG1773	rubredoxin
DXK01_RS07230	COG0784	Response regulator, receiver
DXK01_RS07230	COG2198	Histidine kinase
DXK01_RS07230	COG2205	protein histidine kinase activity
DXK01_RS07235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DXK01_RS07240	COG1011	Hydrolase
DXK01_RS07245	COG0196	riboflavin kinase activity
DXK01_RS07250	COG1266	CAAX protease self-immunity
DXK01_RS07265	COG3655	Transcriptional regulator
DXK01_RS07290	COG2234	aminopeptidase activity
DXK01_RS07300	COG0280	phosphate acetyltransferase
DXK01_RS07305	COG3426	butyrate kinase activity
DXK01_RS07325	COG1629	transport
DXK01_RS07325	COG4206	TonB-dependent receptor
DXK01_RS07345	COG1185	polyribonucleotide nucleotidyltransferase activity
DXK01_RS07355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DXK01_RS07360	COG0537	adenosine 5'-monophosphoramidase activity
DXK01_RS07430	COG4804	nuclease activity
DXK01_RS07435	COG4974	Belongs to the 'phage' integrase family
DXK01_RS07450	COG2755	lipolytic protein G-D-S-L family
DXK01_RS07450	COG0657	acetylesterase activity
DXK01_RS07465	COG1629	transport
DXK01_RS07470	COG0702	epimerase
DXK01_RS07495	COG2096	Adenosyltransferase
DXK01_RS07505	COG0514	ATP-dependent DNA helicase (RecQ)
DXK01_RS07520	COG3189	MarR family transcriptional regulator
DXK01_RS07530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DXK01_RS07555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DXK01_RS07630	COG1752	Esterase of the alpha-beta hydrolase superfamily
DXK01_RS07650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXK01_RS07670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DXK01_RS07680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DXK01_RS07690	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DXK01_RS07695	COG4974	Belongs to the 'phage' integrase family
DXK01_RS07740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DXK01_RS07745	COG0081	regulation of translation
DXK01_RS07750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DXK01_RS07755	COG0222	ribosome binding
DXK01_RS07760	COG0085	RNA polymerase activity
DXK01_RS07765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DXK01_RS07775	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DXK01_RS07780	COG0049	tRNA binding
DXK01_RS07785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DXK01_RS07790	COG0051	transcription antitermination factor activity, RNA binding
DXK01_RS07795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DXK01_RS07800	COG0088	Forms part of the polypeptide exit tunnel
DXK01_RS07805	COG0089	rRNA binding
DXK01_RS07810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DXK01_RS07815	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DXK01_RS07820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DXK01_RS07825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DXK01_RS07830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DXK01_RS07835	COG0255	Belongs to the universal ribosomal protein uL29 family
DXK01_RS07840	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DXK01_RS07845	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DXK01_RS07850	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DXK01_RS07855	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DXK01_RS07860	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DXK01_RS07865	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DXK01_RS07870	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DXK01_RS07875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DXK01_RS07880	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DXK01_RS07885	COG1841	ribosomal large subunit assembly
DXK01_RS07890	COG0200	Binds to the 23S rRNA
DXK01_RS07895	COG0201	protein transport
DXK01_RS07905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DXK01_RS07910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DXK01_RS07915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DXK01_RS07920	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DXK01_RS07925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DXK01_RS07930	COG0202	RNA polymerase activity
DXK01_RS07935	COG0203	ribosomal protein L17
DXK01_RS07950	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DXK01_RS07980	COG1228	amidohydrolase
DXK01_RS07990	COG2986	histidine ammonia-lyase
DXK01_RS07995	COG1309	transcriptional regulator
DXK01_RS08030	COG1696	Membrane protein involved in D-alanine export
DXK01_RS08040	COG1595	DNA-templated transcription, initiation
DXK01_RS08045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS08060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS08095	COG1629	transport
DXK01_RS08175	COG1131	(ABC) transporter
DXK01_RS08210	COG0564	pseudouridine synthase activity
DXK01_RS08265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DXK01_RS08275	COG0612	Peptidase, M16
DXK01_RS08280	COG0534	Mate efflux family protein
DXK01_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXK01_RS08285	COG2205	protein histidine kinase activity
DXK01_RS08305	COG1132	(ABC) transporter
DXK01_RS08345	COG0784	Response regulator, receiver
DXK01_RS08345	COG2198	Histidine kinase
DXK01_RS08345	COG2205	protein histidine kinase activity
DXK01_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXK01_RS08350	COG0488	(ABC) transporter
DXK01_RS08355	COG3590	peptidase
DXK01_RS08360	COG0138	bifunctional purine biosynthesis protein purh
DXK01_RS08385	COG0772	Belongs to the SEDS family
DXK01_RS08395	COG1774	PSP1 C-terminal conserved region
DXK01_RS08400	COG0470	DNA polymerase III
DXK01_RS08405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DXK01_RS08415	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DXK01_RS08420	COG0826	peptidase U32
DXK01_RS08455	COG0022	dehydrogenase e1 component
DXK01_RS08460	COG0716	FMN binding
DXK01_RS08470	COG3345	alpha-galactosidase
DXK01_RS08475	COG3250	beta-galactosidase activity
DXK01_RS08480	COG3119	arylsulfatase activity
DXK01_RS08485	COG0702	epimerase
DXK01_RS08490	COG1629	transport
DXK01_RS08505	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DXK01_RS08520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DXK01_RS08525	COG0252	asparaginase activity
DXK01_RS08535	COG0460	homoserine dehydrogenase
DXK01_RS08535	COG0527	aspartate kinase activity
DXK01_RS08540	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DXK01_RS08620	COG2755	lipolytic protein G-D-S-L family
DXK01_RS08640	COG3250	beta-galactosidase activity
DXK01_RS08665	COG1501	Belongs to the glycosyl hydrolase 31 family
DXK01_RS08675	COG4771	TonB-dependent receptor
DXK01_RS08680	COG0702	epimerase
DXK01_RS08695	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS08700	COG3250	beta-galactosidase activity
DXK01_RS08730	COG3537	Alpha-1,2-mannosidase
DXK01_RS08735	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS08740	COG0110	maltose O-acetyltransferase activity
DXK01_RS08770	COG1162	GTPase activity
DXK01_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS08780	COG0534	Mate efflux family protein
DXK01_RS08820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXK01_RS08835	COG4974	Belongs to the 'phage' integrase family
DXK01_RS08845	COG0628	permease
DXK01_RS08850	COG1435	thymidine kinase activity
DXK01_RS08860	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DXK01_RS08875	COG2095	MarC family integral membrane protein
DXK01_RS08895	COG4771	TonB-dependent receptor
DXK01_RS08905	COG1629	transport
DXK01_RS08925	COG1373	ATPase (AAA superfamily
DXK01_RS08975	COG1629	transport
DXK01_RS09000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DXK01_RS09010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DXK01_RS09010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DXK01_RS09025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DXK01_RS09030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS09035	COG1162	GTPase activity
DXK01_RS09040	COG0233	cytoplasmic translational termination
DXK01_RS09045	COG0528	UMP kinase activity
DXK01_RS09050	COG0534	Mate efflux family protein
DXK01_RS09075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DXK01_RS09075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DXK01_RS09085	COG0792	nuclease activity
DXK01_RS09110	COG1183	phosphatidylcholine synthase activity
DXK01_RS09115	COG0688	phosphatidylethanolamine metabolic process
DXK01_RS09125	COG3118	belongs to the thioredoxin family
DXK01_RS09145	COG1538	Outer membrane efflux protein
DXK01_RS09160	COG2204	response regulator
DXK01_RS09170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DXK01_RS09180	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DXK01_RS09195	COG1566	PFAM secretion protein HlyD family protein
DXK01_RS09245	COG0582	viral genome integration into host DNA
DXK01_RS09285	COG4946	Tricorn protease homolog
DXK01_RS09285	COG1506	peptidase
DXK01_RS09285	COG0823	Involved in the tonB-independent uptake of proteins
DXK01_RS09305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DXK01_RS09325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXK01_RS09330	COG0742	ribosomal rna small subunit methyltransferase
DXK01_RS09360	COG0739	heme binding
DXK01_RS09380	COG1388	LysM domain
DXK01_RS09380	COG3942	CHAP domain
DXK01_RS09390	COG1475	DNA binding
DXK01_RS09395	COG1192	Involved in chromosome partitioning
DXK01_RS09420	COG4771	TonB-dependent receptor
DXK01_RS09430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DXK01_RS09435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DXK01_RS09450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DXK01_RS09465	COG0519	Catalyzes the synthesis of GMP from XMP
DXK01_RS09470	COG0138	bifunctional purine biosynthesis protein purh
DXK01_RS09475	COG1196	nuclear chromosome segregation
DXK01_RS09480	COG2239	Acts as a magnesium transporter
DXK01_RS09485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DXK01_RS09495	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXK01_RS09595	COG0668	transmembrane transport
DXK01_RS09605	COG1404	Belongs to the peptidase S8 family
DXK01_RS09605	COG4412	M6 family metalloprotease domain protein
DXK01_RS09610	COG0784	Response regulator, receiver
DXK01_RS09610	COG2205	protein histidine kinase activity
DXK01_RS09610	COG5002	protein histidine kinase activity
DXK01_RS09620	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXK01_RS09625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DXK01_RS09630	COG0713	ATP synthesis coupled electron transport
DXK01_RS09635	COG0839	Belongs to the complex I subunit 6 family
DXK01_RS09640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXK01_RS09645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DXK01_RS09650	COG0649	NAD binding
DXK01_RS09650	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXK01_RS09655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXK01_RS09660	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DXK01_RS09670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DXK01_RS09675	COG0569	domain protein
DXK01_RS09680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DXK01_RS09695	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DXK01_RS09700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DXK01_RS09705	COG0805	protein transport
DXK01_RS09715	COG2271	Major facilitator Superfamily
DXK01_RS09720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS09730	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS09735	COG2755	lipolytic protein G-D-S-L family
DXK01_RS09740	COG3458	cephalosporin-C deacetylase activity
DXK01_RS09745	COG4771	TonB-dependent receptor
DXK01_RS09755	COG1073	alpha beta
DXK01_RS09760	COG3292	Two component regulator propeller
DXK01_RS09760	COG0745	RESPONSE REGULATOR receiver
DXK01_RS09760	COG2205	protein histidine kinase activity
DXK01_RS09770	COG3292	Two component regulator propeller
DXK01_RS09770	COG2205	protein histidine kinase activity
DXK01_RS09770	COG0745	RESPONSE REGULATOR receiver
DXK01_RS09780	COG4206	TonB-dependent receptor
DXK01_RS09780	COG1629	transport
DXK01_RS09790	COG0702	epimerase
DXK01_RS09795	COG4771	TonB-dependent receptor
DXK01_RS09805	COG0546	phosphoglycolate phosphatase activity
DXK01_RS09825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DXK01_RS09830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DXK01_RS09840	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DXK01_RS09845	COG1506	peptidase
DXK01_RS09845	COG0823	Involved in the tonB-independent uptake of proteins
DXK01_RS09860	COG4821	SIS domain
DXK01_RS09865	COG2814	Major facilitator Superfamily
DXK01_RS09870	COG1940	carbohydrate kinase activity
DXK01_RS09875	COG1242	4 iron, 4 sulfur cluster binding
DXK01_RS09885	COG0363	glucosamine-6-phosphate deaminase activity
DXK01_RS09915	COG0628	permease
DXK01_RS09920	COG0009	L-threonylcarbamoyladenylate synthase
DXK01_RS09925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DXK01_RS09930	COG0561	phosphatase activity
DXK01_RS09945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DXK01_RS09970	COG1629	transport
DXK01_RS09970	COG4206	TonB-dependent receptor
DXK01_RS09975	COG0702	epimerase
DXK01_RS09985	COG2205	protein histidine kinase activity
DXK01_RS09985	COG3292	Two component regulator propeller
DXK01_RS09985	COG0745	RESPONSE REGULATOR receiver
DXK01_RS09995	COG1073	alpha beta
DXK01_RS10030	COG4206	TonB-dependent receptor
DXK01_RS10030	COG1629	transport
DXK01_RS10040	COG4206	TonB-dependent receptor
DXK01_RS10040	COG1629	transport
DXK01_RS10045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DXK01_RS10055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DXK01_RS10070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DXK01_RS10070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DXK01_RS10075	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DXK01_RS10080	COG1078	dGTPase activity
DXK01_RS10085	COG0284	orotidine-5'-phosphate decarboxylase activity
DXK01_RS10095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DXK01_RS10105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DXK01_RS10150	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DXK01_RS10155	COG2226	methyltransferase
DXK01_RS10160	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DXK01_RS10165	COG1702	phosphate starvation-inducible protein PhoH
DXK01_RS10180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DXK01_RS10185	COG1496	oxidoreductase activity
DXK01_RS10190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DXK01_RS10205	COG0563	adenylate kinase activity
DXK01_RS10210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DXK01_RS10230	COG0242	peptide deformylase activity
DXK01_RS10250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS10255	COG3250	beta-galactosidase activity
DXK01_RS10260	COG3119	arylsulfatase activity
DXK01_RS10265	COG3292	Two component regulator propeller
DXK01_RS10265	COG2205	protein histidine kinase activity
DXK01_RS10265	COG0745	RESPONSE REGULATOR receiver
DXK01_RS10275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DXK01_RS10275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DXK01_RS10285	COG0101	tRNA pseudouridine synthase activity
DXK01_RS10295	COG1956	GAF domain-containing protein
DXK01_RS10305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DXK01_RS10320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DXK01_RS10325	COG1690	Belongs to the RtcB family
DXK01_RS10340	COG0673	inositol 2-dehydrogenase activity
DXK01_RS10345	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS10360	COG1484	DNA-dependent DNA replication
DXK01_RS10365	COG4584	PFAM Integrase catalytic
DXK01_RS10375	COG4974	Belongs to the 'phage' integrase family
DXK01_RS10390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DXK01_RS10420	COG0793	Belongs to the peptidase S41A family
DXK01_RS10425	COG2131	deaminase
DXK01_RS10435	COG0339	signal peptide processing
DXK01_RS10445	COG1970	mechanosensitive ion channel activity
DXK01_RS10450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DXK01_RS10450	COG0519	Catalyzes the synthesis of GMP from XMP
DXK01_RS10455	COG3292	Two component regulator propeller
DXK01_RS10455	COG2205	protein histidine kinase activity
DXK01_RS10455	COG2205	protein histidine kinase activity
DXK01_RS10455	COG3292	Two component regulator propeller
DXK01_RS10455	COG0745	RESPONSE REGULATOR receiver
DXK01_RS10455	COG0745	RESPONSE REGULATOR receiver
DXK01_RS10460	COG3254	rhamnose metabolic process
DXK01_RS10465	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS10470	COG3401	FG-GAP repeat protein
DXK01_RS10480	COG3401	FG-GAP repeat protein
DXK01_RS10485	COG3250	beta-galactosidase activity
DXK01_RS10490	COG3401	FG-GAP repeat protein
DXK01_RS10500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DXK01_RS10505	COG1629	transport
DXK01_RS10515	COG4771	TonB-dependent receptor
DXK01_RS10550	COG2755	lipolytic protein G-D-S-L family
DXK01_RS10570	COG2431	L-lysine efflux transmembrane transporter activity
DXK01_RS10585	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS10600	COG0297	glycogen (starch) synthase activity
DXK01_RS10605	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DXK01_RS10610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DXK01_RS10615	COG0543	2 iron, 2 sulfur cluster binding
DXK01_RS10620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DXK01_RS10625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DXK01_RS10630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DXK01_RS10655	COG0546	phosphoglycolate phosphatase activity
DXK01_RS10660	COG3537	Alpha-1,2-mannosidase
DXK01_RS10680	COG1629	transport
DXK01_RS10705	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS10710	COG3537	Alpha-1,2-mannosidase
DXK01_RS10720	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DXK01_RS10725	COG3537	Alpha-1,2-mannosidase
DXK01_RS10755	COG1086	Polysaccharide biosynthesis protein
DXK01_RS10760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXK01_RS10765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DXK01_RS10770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DXK01_RS10775	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS10790	COG2089	acid synthase
DXK01_RS10795	COG1083	cytidylyl-transferase
DXK01_RS10800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DXK01_RS10820	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS10830	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS10835	COG3754	Rhamnan synthesis protein F
DXK01_RS10845	COG1442	glycosyl transferase family 8
DXK01_RS10845	COG1216	Glycosyl transferase, family 2
DXK01_RS10855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXK01_RS10860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXK01_RS10875	COG0791	NLP P60 protein
DXK01_RS10890	COG0612	Peptidase, M16
DXK01_RS10895	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DXK01_RS10900	COG1597	lipid kinase activity
DXK01_RS10905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DXK01_RS10925	COG0612	Peptidase, M16
DXK01_RS10940	COG4771	TonB-dependent receptor
DXK01_RS10945	COG0561	phosphatase activity
DXK01_RS10955	COG0702	epimerase
DXK01_RS10980	COG2382	esterase
DXK01_RS10980	COG3693	PFAM glycoside hydrolase, family 10
DXK01_RS10980	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS10985	COG2382	esterase
DXK01_RS10990	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DXK01_RS10995	COG0745	RESPONSE REGULATOR receiver
DXK01_RS10995	COG3292	Two component regulator propeller
DXK01_RS10995	COG2205	protein histidine kinase activity
DXK01_RS11005	COG3661	Belongs to the glycosyl hydrolase 67 family
DXK01_RS11010	COG0673	inositol 2-dehydrogenase activity
DXK01_RS11025	COG2211	Major facilitator Superfamily
DXK01_RS11050	COG0561	phosphatase activity
DXK01_RS11055	COG4206	TonB-dependent receptor
DXK01_RS11055	COG1629	transport
DXK01_RS11060	COG3292	Two component regulator propeller
DXK01_RS11060	COG0745	RESPONSE REGULATOR receiver
DXK01_RS11060	COG2205	protein histidine kinase activity
DXK01_RS11065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXK01_RS11075	COG1136	(ABC) transporter
DXK01_RS11095	COG2211	Major facilitator Superfamily
DXK01_RS11105	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DXK01_RS11125	COG1674	ftsk spoiiie
DXK01_RS11135	COG0492	ferredoxin-NADP+ reductase activity
DXK01_RS11140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS11165	COG4771	TonB-dependent receptor
DXK01_RS11190	COG0148	phosphopyruvate hydratase activity
DXK01_RS11195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DXK01_RS11200	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS11220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DXK01_RS11235	COG2244	polysaccharide biosynthetic process
DXK01_RS11245	COG1216	Glycosyl transferase, family 2
DXK01_RS11245	COG1442	glycosyl transferase family 8
DXK01_RS11275	COG1216	Glycosyl transferase, family 2
DXK01_RS11280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXK01_RS11285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXK01_RS11290	COG2814	Major facilitator Superfamily
DXK01_RS11295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DXK01_RS11300	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXK01_RS11305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DXK01_RS11320	COG0254	rRNA binding
DXK01_RS11330	COG0191	fructose-bisphosphate aldolase activity
DXK01_RS11355	COG1846	Transcriptional regulator
DXK01_RS11360	COG0366	Alpha amylase catalytic
DXK01_RS11370	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DXK01_RS11375	COG0511	ligase activity, forming carbon-carbon bonds
DXK01_RS11385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DXK01_RS11415	COG2183	response to ionizing radiation
DXK01_RS11415	COG0539	negative regulation of cytoplasmic translation
DXK01_RS11435	COG4974	Belongs to the 'phage' integrase family
DXK01_RS11460	COG3956	TIGRFAM MazG family protein
DXK01_RS11475	COG0525	valine-tRNA ligase activity
DXK01_RS11490	COG0653	protein targeting
DXK01_RS11495	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
DXK01_RS11505	COG0105	UTP biosynthetic process
DXK01_RS11510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DXK01_RS11530	COG1253	flavin adenine dinucleotide binding
DXK01_RS11540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DXK01_RS11550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DXK01_RS11590	COG2706	6-phosphogluconolactonase activity
DXK01_RS11595	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS11620	COG0534	Mate efflux family protein
DXK01_RS11675	COG3142	Participates in the control of copper homeostasis
DXK01_RS11680	COG1418	mRNA catabolic process
DXK01_RS11730	COG1595	DNA-templated transcription, initiation
DXK01_RS11740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DXK01_RS11745	COG2832	Protein of unknown function (DUF454)
DXK01_RS11760	COG0602	queuosine metabolic process
DXK01_RS11780	COG1509	lysine 2,3-aminomutase activity
DXK01_RS11790	COG1115	amino acid carrier protein
DXK01_RS11815	COG1285	pathogenesis
DXK01_RS11820	COG0741	lytic transglycosylase activity
DXK01_RS11820	COG1388	LysM domain
DXK01_RS11840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DXK01_RS11845	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS11860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DXK01_RS11955	COG2814	Major facilitator Superfamily
DXK01_RS11970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DXK01_RS11980	COG0564	pseudouridine synthase activity
DXK01_RS11990	COG0346	lactoylglutathione lyase activity
DXK01_RS11995	COG0513	Belongs to the DEAD box helicase family
DXK01_RS12060	COG4942	peptidase
DXK01_RS12130	COG3546	catalase activity
DXK01_RS12155	COG0668	transmembrane transport
DXK01_RS12185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DXK01_RS12230	COG1063	alcohol dehydrogenase
DXK01_RS12270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXK01_RS12290	COG3550	peptidyl-serine autophosphorylation
DXK01_RS12300	COG0537	adenosine 5'-monophosphoramidase activity
DXK01_RS12335	COG1910	domain protein
DXK01_RS12355	COG4974	Belongs to the 'phage' integrase family
DXK01_RS12365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DXK01_RS12375	COG0813	purine-nucleoside phosphorylase activity
DXK01_RS12380	COG4864	UPF0365 protein
DXK01_RS12395	COG0037	tRNA processing
DXK01_RS12405	COG1477	protein flavinylation
DXK01_RS12410	COG1971	Probably functions as a manganese efflux pump
DXK01_RS12425	COG0463	Glycosyl transferase, family 2
DXK01_RS12460	COG4651	solute:proton antiporter activity
DXK01_RS12460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DXK01_RS12470	COG0673	inositol 2-dehydrogenase activity
DXK01_RS12475	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DXK01_RS12480	COG0193	aminoacyl-tRNA hydrolase activity
DXK01_RS12485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DXK01_RS12495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DXK01_RS12500	COG1862	Preprotein translocase
DXK01_RS12510	COG0237	dephospho-CoA kinase activity
DXK01_RS12525	COG0542	response to heat
DXK01_RS12535	COG0583	DNA-binding transcription factor activity
DXK01_RS12540	COG2855	membrane
DXK01_RS12545	COG1595	DNA-templated transcription, initiation
DXK01_RS12560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DXK01_RS12565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DXK01_RS12580	COG2076	Multidrug Resistance protein
DXK01_RS12595	COG0534	Mate efflux family protein
DXK01_RS12600	COG0443	Heat shock 70 kDa protein
DXK01_RS12725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DXK01_RS12730	COG1595	DNA-templated transcription, initiation
DXK01_RS12755	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DXK01_RS12760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DXK01_RS12770	COG1733	regulation of RNA biosynthetic process
DXK01_RS12775	COG0656	L-ascorbic acid biosynthetic process
DXK01_RS12780	COG0667	Aldo Keto reductase
DXK01_RS12790	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DXK01_RS12795	COG0534	Mate efflux family protein
DXK01_RS12800	COG3275	phosphorelay sensor kinase activity
DXK01_RS12805	COG3279	Response regulator of the LytR AlgR family
DXK01_RS12810	COG4206	TonB-dependent receptor
DXK01_RS12835	COG0693	protein deglycase activity
DXK01_RS12840	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS12855	COG5002	protein histidine kinase activity
DXK01_RS12855	COG3850	Histidine kinase
DXK01_RS12870	COG1760	l-serine dehydratase
DXK01_RS12875	COG1193	negative regulation of DNA recombination
DXK01_RS12900	COG0745	RESPONSE REGULATOR receiver
DXK01_RS12900	COG3292	Two component regulator propeller
DXK01_RS12900	COG2205	protein histidine kinase activity
DXK01_RS12905	COG3940	Belongs to the glycosyl hydrolase 43 family
DXK01_RS12915	COG4771	TonB-dependent receptor
DXK01_RS12920	COG0702	epimerase
DXK01_RS12925	COG1629	transport
DXK01_RS12930	COG0702	epimerase
DXK01_RS12980	COG0738	Major facilitator superfamily
DXK01_RS12985	COG1063	alcohol dehydrogenase
DXK01_RS12990	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DXK01_RS13010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DXK01_RS13035	COG0798	PFAM Bile acid sodium symporter
DXK01_RS13040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DXK01_RS13075	COG3292	Two component regulator propeller
DXK01_RS13075	COG0745	RESPONSE REGULATOR receiver
DXK01_RS13075	COG2205	protein histidine kinase activity
DXK01_RS13085	COG1830	Aldolase
DXK01_RS13130	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXK01_RS13175	COG1051	belongs to the nudix hydrolase family
DXK01_RS13185	COG2197	response regulator
DXK01_RS13220	COG2217	Heavy metal translocating P-type atpase
DXK01_RS13235	COG2205	protein histidine kinase activity
DXK01_RS13235	COG2198	Histidine kinase
DXK01_RS13235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXK01_RS13235	COG0784	Response regulator, receiver
DXK01_RS13280	COG4753	response regulator
DXK01_RS13280	COG2207	Transcriptional regulator
DXK01_RS13295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS13300	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DXK01_RS13305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DXK01_RS13315	COG0784	Response regulator, receiver
DXK01_RS13315	COG2205	protein histidine kinase activity
DXK01_RS13335	COG1918	ferrous iron import across plasma membrane
DXK01_RS13335	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DXK01_RS13360	COG0490	domain, Protein
DXK01_RS13360	COG0471	metal ion transport
DXK01_RS13365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS13380	COG0346	lactoylglutathione lyase activity
DXK01_RS13395	COG1741	Belongs to the pirin family
DXK01_RS13400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DXK01_RS13445	COG1629	transport
DXK01_RS13445	COG4206	TonB-dependent receptor
DXK01_RS13455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DXK01_RS13460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DXK01_RS13470	COG2205	protein histidine kinase activity
DXK01_RS13470	COG3850	Histidine kinase
DXK01_RS13470	COG4999	Histidine kinase
DXK01_RS13470	COG3437	response regulator, receiver
DXK01_RS13475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS13485	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS13505	COG1484	DNA-dependent DNA replication
DXK01_RS13510	COG4584	PFAM Integrase catalytic
DXK01_RS13545	COG4206	TonB-dependent receptor
DXK01_RS13545	COG1629	transport
DXK01_RS13555	COG1595	DNA-templated transcription, initiation
DXK01_RS13575	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DXK01_RS13585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXK01_RS13610	COG1151	hydroxylamine reductase activity
DXK01_RS13675	COG1333	cytochrome c biogenesis protein
DXK01_RS13675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXK01_RS13685	COG0716	FMN binding
DXK01_RS13690	COG2949	membrane
DXK01_RS13695	COG2223	nitrite transmembrane transporter activity
DXK01_RS13705	COG0351	phosphomethylpyrimidine kinase
DXK01_RS13720	COG2205	protein histidine kinase activity
DXK01_RS13720	COG2198	Histidine kinase
DXK01_RS13720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXK01_RS13720	COG0784	Response regulator, receiver
DXK01_RS13750	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DXK01_RS13760	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DXK01_RS13770	COG1979	alcohol dehydrogenase
DXK01_RS13800	COG0724	RNA recognition motif
DXK01_RS13815	COG0738	Major facilitator superfamily
DXK01_RS13830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DXK01_RS13860	COG1979	alcohol dehydrogenase
DXK01_RS13880	COG3552	Protein containing von Willebrand factor type A (VWA) domain
DXK01_RS13890	COG0714	Associated with various cellular activities
DXK01_RS13965	COG0745	RESPONSE REGULATOR receiver
DXK01_RS13970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DXK01_RS14000	COG0788	formyltetrahydrofolate deformylase activity
DXK01_RS14005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DXK01_RS14010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DXK01_RS14015	COG0107	imidazoleglycerol-phosphate synthase activity
DXK01_RS14020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DXK01_RS14020	COG0140	phosphoribosyl-ATP diphosphatase activity
DXK01_RS14025	COG2884	Cell division ATP-binding protein ftsE
DXK01_RS14030	COG0527	aspartate kinase activity
DXK01_RS14035	COG0019	diaminopimelate decarboxylase activity
DXK01_RS14050	COG0156	8-amino-7-oxononanoate synthase activity
DXK01_RS14120	COG0629	single-stranded DNA binding
DXK01_RS14140	COG1061	Type III restriction enzyme res subunit
DXK01_RS14160	COG1475	DNA binding
DXK01_RS14195	COG4584	PFAM Integrase catalytic
DXK01_RS14200	COG1484	DNA-dependent DNA replication
DXK01_RS14225	COG1595	DNA-templated transcription, initiation
DXK01_RS14280	COG2135	peptidase activity
DXK01_RS14315	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DXK01_RS14315	COG0321	lipoyl(octanoyl) transferase activity
DXK01_RS14330	COG0592	DNA-directed DNA polymerase activity
DXK01_RS14350	COG0497	DNA recombination
DXK01_RS14355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXK01_RS14365	COG0251	oxidation-reduction process
DXK01_RS14375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DXK01_RS14385	COG0167	dihydroorotate dehydrogenase activity
DXK01_RS14390	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DXK01_RS14410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DXK01_RS14425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DXK01_RS14435	COG0573	inorganic phosphate transmembrane transporter activity
DXK01_RS14440	COG0581	inorganic phosphate transmembrane transporter activity
DXK01_RS14445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DXK01_RS14450	COG0704	Plays a role in the regulation of phosphate uptake
DXK01_RS14460	COG0778	Nitroreductase
DXK01_RS14465	COG1295	ribonuclease BN
DXK01_RS14480	COG4948	Mandelate Racemase Muconate Lactonizing
DXK01_RS14490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DXK01_RS14495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DXK01_RS14510	COG0446	pyridine nucleotide-disulphide oxidoreductase
DXK01_RS14530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DXK01_RS14555	COG1595	DNA-templated transcription, initiation
DXK01_RS14580	COG0531	amino acid
DXK01_RS14590	COG2066	Belongs to the glutaminase family
DXK01_RS14595	COG0076	glutamate decarboxylase activity
DXK01_RS14615	COG3275	phosphorelay sensor kinase activity
DXK01_RS14620	COG3279	Response regulator of the LytR AlgR family
DXK01_RS14625	COG0686	Belongs to the AlaDH PNT family
DXK01_RS14630	COG0739	heme binding
DXK01_RS14640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DXK01_RS14655	COG3279	Response regulator of the LytR AlgR family
DXK01_RS14680	COG0488	(ABC) transporter
DXK01_RS14690	COG0295	cytidine deaminase activity
DXK01_RS14695	COG1705	Flagellar rod assembly protein muramidase FlgJ
DXK01_RS14700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS14715	COG1136	(ABC) transporter
DXK01_RS14715	COG0577	efflux transmembrane transporter activity
DXK01_RS14725	COG0577	efflux transmembrane transporter activity
DXK01_RS14730	COG0577	efflux transmembrane transporter activity
DXK01_RS14735	COG1136	(ABC) transporter
DXK01_RS14740	COG0577	efflux transmembrane transporter activity
DXK01_RS14755	COG0577	efflux transmembrane transporter activity
DXK01_RS14765	COG0577	efflux transmembrane transporter activity
DXK01_RS14765	COG1136	(ABC) transporter
DXK01_RS14785	COG5002	protein histidine kinase activity
DXK01_RS14785	COG0784	Response regulator, receiver
DXK01_RS14800	COG0436	Aminotransferase
DXK01_RS14805	COG4591	ABC-type transport system involved in lipoprotein release permease component
DXK01_RS14810	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS14820	COG2226	methyltransferase
DXK01_RS14835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DXK01_RS14835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DXK01_RS14850	COG3973	AAA domain
DXK01_RS14865	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS14885	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DXK01_RS14890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DXK01_RS14895	COG1663	tetraacyldisaccharide 4'-kinase activity
DXK01_RS14900	COG0616	signal peptide processing
DXK01_RS14955	COG4804	nuclease activity
DXK01_RS15010	COG0776	regulation of translation
DXK01_RS15015	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS15055	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DXK01_RS15075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXK01_RS15085	COG0058	SHG alpha-glucan phosphorylase activity
DXK01_RS15090	COG0588	phosphoglycerate mutase activity
DXK01_RS15100	COG3610	response to peptide
DXK01_RS15105	COG2966	Psort location CytoplasmicMembrane, score
DXK01_RS15110	COG0602	queuosine metabolic process
DXK01_RS15115	COG1328	CTP reductase activity
DXK01_RS15120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DXK01_RS15125	COG0228	four-way junction DNA binding
DXK01_RS15155	COG2721	sulfolactate sulfo-lyase activity
DXK01_RS15160	COG1609	Transcriptional regulator
DXK01_RS15185	COG1858	cytochrome C peroxidase
DXK01_RS15195	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS15200	COG0463	Glycosyl transferase, family 2
DXK01_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS15225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DXK01_RS15230	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS15260	COG0110	maltose O-acetyltransferase activity
DXK01_RS15295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXK01_RS15300	COG0745	RESPONSE REGULATOR receiver
DXK01_RS15315	COG0252	asparaginase activity
DXK01_RS15320	COG0159	tryptophan synthase activity
DXK01_RS15325	COG0135	phosphoribosylanthranilate isomerase activity
DXK01_RS15330	COG0134	indole-3-glycerol-phosphate synthase activity
DXK01_RS15335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXK01_RS15340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DXK01_RS15340	COG0512	Glutamine amidotransferase of anthranilate synthase
DXK01_RS15345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DXK01_RS15350	COG0133	tryptophan synthase activity
DXK01_RS15375	COG0004	ammonium transporteR
DXK01_RS15380	COG0347	Belongs to the P(II) protein family
DXK01_RS15390	COG0436	Aminotransferase
DXK01_RS15410	COG1177	transmembrane transport
DXK01_RS15415	COG1176	ABC-type spermidine putrescine transport system, permease component I
DXK01_RS15420	COG3842	ATPase activity
DXK01_RS15430	COG0367	asparagine synthase
DXK01_RS15440	COG0067	glutamate synthase
DXK01_RS15440	COG0070	glutamate synthase
DXK01_RS15440	COG0069	glutamate synthase activity
DXK01_RS15445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXK01_RS15450	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DXK01_RS15455	COG0505	Belongs to the CarA family
DXK01_RS15460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DXK01_RS15480	COG1070	Carbohydrate kinase
DXK01_RS15490	COG0738	Major facilitator superfamily
DXK01_RS15495	COG2198	Histidine kinase
DXK01_RS15495	COG2205	protein histidine kinase activity
DXK01_RS15495	COG0784	Response regulator, receiver
DXK01_RS15500	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS15500	COG2207	Transcriptional regulator
DXK01_RS15515	COG1131	(ABC) transporter
DXK01_RS15520	COG0842	Transport permease protein
DXK01_RS15525	COG0842	Transport permease protein
DXK01_RS15530	COG2755	lipolytic protein G-D-S-L family
DXK01_RS15530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DXK01_RS15540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DXK01_RS15555	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS15555	COG2207	Transcriptional regulator
DXK01_RS15560	COG0110	maltose O-acetyltransferase activity
DXK01_RS15565	COG0798	PFAM Bile acid sodium symporter
DXK01_RS15605	COG4771	TonB-dependent receptor
DXK01_RS15610	COG0702	epimerase
DXK01_RS15630	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS15650	COG1022	Amp-dependent synthetase and ligase
DXK01_RS15660	COG3263	regulation of cellular component size
DXK01_RS15665	COG4191	Histidine kinase
DXK01_RS15690	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DXK01_RS15695	COG1058	Belongs to the CinA family
DXK01_RS15695	COG1546	Belongs to the CinA family
DXK01_RS15700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DXK01_RS15705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DXK01_RS15715	COG0552	protein localization to endoplasmic reticulum
DXK01_RS15720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DXK01_RS15735	COG0714	Associated with various cellular activities
DXK01_RS15750	COG2304	oxidoreductase activity
DXK01_RS15795	COG0542	response to heat
DXK01_RS15800	COG0326	Molecular chaperone. Has ATPase activity
DXK01_RS15820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DXK01_RS15830	COG0336	Belongs to the RNA methyltransferase TrmD family
DXK01_RS15835	COG0167	dihydroorotate dehydrogenase activity
DXK01_RS15840	COG0543	2 iron, 2 sulfur cluster binding
DXK01_RS15855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DXK01_RS15885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DXK01_RS15900	COG1136	(ABC) transporter
DXK01_RS15910	COG2957	Belongs to the agmatine deiminase family
DXK01_RS15925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DXK01_RS15930	COG1597	lipid kinase activity
DXK01_RS15935	COG0156	8-amino-7-oxononanoate synthase activity
DXK01_RS15940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DXK01_RS15940	COG2755	lipolytic protein G-D-S-L family
DXK01_RS15950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DXK01_RS15955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DXK01_RS15965	COG1136	(ABC) transporter
DXK01_RS16025	COG4191	Histidine kinase
DXK01_RS16055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DXK01_RS16060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DXK01_RS16065	COG0343	queuine tRNA-ribosyltransferase activity
DXK01_RS16080	COG0560	Phosphoserine phosphatase
DXK01_RS16080	COG3830	Belongs to the UPF0237 family
DXK01_RS16090	COG0702	epimerase
DXK01_RS16095	COG0513	Belongs to the DEAD box helicase family
DXK01_RS16120	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXK01_RS16130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DXK01_RS16135	COG0297	glycogen (starch) synthase activity
DXK01_RS16200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DXK01_RS16210	COG4206	TonB-dependent receptor
DXK01_RS16210	COG1629	transport
DXK01_RS16295	COG0246	Mannitol dehydrogenase
DXK01_RS16305	COG1904	glucuronate isomerase
DXK01_RS16330	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DXK01_RS16345	COG2194	sulfuric ester hydrolase activity
DXK01_RS16355	COG1252	NADH dehydrogenase
DXK01_RS16375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DXK01_RS16390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DXK01_RS16400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DXK01_RS16405	COG2249	NAD(P)H dehydrogenase (quinone) activity
DXK01_RS16430	COG3153	acetyltransferase
DXK01_RS16430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXK01_RS16440	COG0477	Major facilitator Superfamily
DXK01_RS16440	COG2814	Major facilitator Superfamily
DXK01_RS16445	COG2115	Belongs to the xylose isomerase family
DXK01_RS16450	COG1070	Carbohydrate kinase
DXK01_RS16460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DXK01_RS16480	COG0519	Catalyzes the synthesis of GMP from XMP
DXK01_RS16550	COG2226	methyltransferase
DXK01_RS16575	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DXK01_RS16580	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DXK01_RS16610	COG2731	YhcH YjgK YiaL family protein
DXK01_RS16615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DXK01_RS16645	COG2197	response regulator
DXK01_RS16655	COG1484	DNA-dependent DNA replication
DXK01_RS16660	COG4584	PFAM Integrase catalytic
DXK01_RS16730	COG2205	protein histidine kinase activity
DXK01_RS16735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DXK01_RS16750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DXK01_RS16760	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DXK01_RS16765	COG0540	Belongs to the ATCase OTCase family
DXK01_RS16770	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DXK01_RS16785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DXK01_RS16790	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DXK01_RS16800	COG0577	efflux transmembrane transporter activity
DXK01_RS16800	COG1136	(ABC) transporter
DXK01_RS16815	COG3852	Histidine kinase
DXK01_RS16820	COG1454	alcohol dehydrogenase
DXK01_RS16860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DXK01_RS16865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DXK01_RS16870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DXK01_RS16875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXK01_RS16880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DXK01_RS16885	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DXK01_RS16890	COG0356	it plays a direct role in the translocation of protons across the membrane
DXK01_RS16910	COG2837	iron assimilation
DXK01_RS16920	COG1181	Belongs to the D-alanine--D-alanine ligase family
DXK01_RS16930	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DXK01_RS16935	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DXK01_RS16945	COG0724	RNA recognition motif
DXK01_RS16960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DXK01_RS16975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DXK01_RS16980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DXK01_RS16985	COG0534	Mate efflux family protein
DXK01_RS17005	COG1136	(ABC) transporter
DXK01_RS17005	COG0577	efflux transmembrane transporter activity
DXK01_RS17020	COG0442	prolyl-tRNA aminoacylation
DXK01_RS17040	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXK01_RS17050	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXK01_RS17060	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DXK01_RS17060	COG0463	Glycosyl transferase, family 2
DXK01_RS17065	COG1216	Glycosyl transferase, family 2
DXK01_RS17105	COG0647	UMP catabolic process
DXK01_RS17110	COG1213	nucleotidyl transferase
DXK01_RS17120	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXK01_RS17190	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
DXK01_RS17195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DXK01_RS17210	COG2205	protein histidine kinase activity
DXK01_RS17215	COG2198	Histidine kinase
DXK01_RS17215	COG0784	Response regulator, receiver
DXK01_RS17215	COG2205	protein histidine kinase activity
DXK01_RS17220	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DXK01_RS17230	COG1492	cobalamin metabolic process
DXK01_RS17235	COG2205	protein histidine kinase activity
DXK01_RS17260	COG1797	cobyrinic acid a,c-diamide synthase activity
DXK01_RS17265	COG1660	Displays ATPase and GTPase activities
DXK01_RS17270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DXK01_RS17295	COG4771	TonB-dependent receptor
DXK01_RS17320	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DXK01_RS17325	COG0300	oxidoreductase activity
DXK01_RS17350	COG1120	ATPase activity
DXK01_RS17365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXK01_RS17370	COG3059	membrane
DXK01_RS17375	COG0662	Cupin 2, conserved barrel domain protein
DXK01_RS17375	COG2207	Transcriptional regulator
DXK01_RS17380	COG1687	branched-chain amino acid
DXK01_RS17400	COG0657	acetylesterase activity
DXK01_RS17400	COG2755	lipolytic protein G-D-S-L family
DXK01_RS17405	COG3250	beta-galactosidase activity
DXK01_RS17425	COG1695	Transcriptional regulator
DXK01_RS17435	COG3104	oligopeptide transport
DXK01_RS17440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DXK01_RS17455	COG1388	LysM domain
DXK01_RS17455	COG1705	Flagellar rod assembly protein muramidase FlgJ
DXK01_RS17485	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DXK01_RS17495	COG0556	nucleotide-excision repair
DXK01_RS17515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXK01_RS17520	COG1475	DNA binding
DXK01_RS17525	COG3969	phosphoadenosine phosphosulfate
DXK01_RS17560	COG0714	Associated with various cellular activities
DXK01_RS17585	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DXK01_RS17605	COG4771	TonB-dependent receptor
DXK01_RS17610	COG1678	Uncharacterized ACR, COG1678
DXK01_RS17630	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DXK01_RS17635	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DXK01_RS17695	COG0352	thiamine-phosphate diphosphorylase activity
DXK01_RS17705	COG0574	Belongs to the PEP-utilizing enzyme family
DXK01_RS17705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DXK01_RS17710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DXK01_RS17715	COG0564	pseudouridine synthase activity
DXK01_RS17730	COG2814	Major facilitator Superfamily
DXK01_RS17735	COG0386	Belongs to the glutathione peroxidase family
DXK01_RS17750	COG0420	3'-5' exonuclease activity
DXK01_RS17760	COG0024	Methionine aminopeptidase
DXK01_RS17770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DXK01_RS17785	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DXK01_RS17795	COG0481	GTPase activity
DXK01_RS17805	COG0259	pyridoxamine-phosphate oxidase activity
DXK01_RS17820	COG0708	Exodeoxyribonuclease III
DXK01_RS17835	COG0217	transcriptional regulatory protein
DXK01_RS17840	COG0072	phenylalanine-tRNA ligase activity
DXK01_RS17840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DXK01_RS17855	COG0305	Participates in initiation and elongation during chromosome replication
DXK01_RS17865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DXK01_RS17885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DXK01_RS17895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXK01_RS17950	COG1215	transferase activity, transferring glycosyl groups
DXK01_RS17990	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DXK01_RS18000	COG3254	rhamnose metabolic process
DXK01_RS18010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS18015	COG1028	Short-chain dehydrogenase reductase Sdr
DXK01_RS18020	COG1904	glucuronate isomerase
DXK01_RS18030	COG1312	Catalyzes the dehydration of D-mannonate
DXK01_RS18035	COG4145	pantothenate transmembrane transporter activity
DXK01_RS18050	COG4771	TonB-dependent receptor
DXK01_RS18055	COG1414	Transcriptional regulator
DXK01_RS18060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DXK01_RS18065	COG4657	Part of a membrane complex involved in electron transport
DXK01_RS18070	COG4660	Part of a membrane complex involved in electron transport
DXK01_RS18075	COG4659	FMN binding
DXK01_RS18080	COG4658	electron transport chain
DXK01_RS18085	COG4656	Part of a membrane complex involved in electron transport
DXK01_RS18105	COG0504	CTP synthase activity
DXK01_RS18115	COG0534	Mate efflux family protein
DXK01_RS18120	COG1506	peptidase
DXK01_RS18120	COG0823	Involved in the tonB-independent uptake of proteins
DXK01_RS18125	COG0321	lipoyl(octanoyl) transferase activity
DXK01_RS18135	COG2217	Heavy metal translocating P-type atpase
DXK01_RS18145	COG1629	transport
DXK01_RS18145	COG4206	TonB-dependent receptor
DXK01_RS18160	COG0357	Ribosomal RNA small subunit methyltransferase G
DXK01_RS18165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DXK01_RS18170	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DXK01_RS18170	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DXK01_RS18175	COG1272	protein, Hemolysin III
DXK01_RS18185	COG1131	(ABC) transporter
DXK01_RS18195	COG1725	Transcriptional regulator
DXK01_RS18205	COG0778	Nitroreductase
DXK01_RS18220	COG1739	Uncharacterized protein family UPF0029
DXK01_RS18230	COG1929	Belongs to the glycerate kinase type-1 family
DXK01_RS18235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DXK01_RS18240	COG0545	Peptidyl-prolyl cis-trans isomerase
DXK01_RS18245	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DXK01_RS18285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DXK01_RS18290	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DXK01_RS18295	COG0513	Belongs to the DEAD box helicase family
DXK01_RS18300	COG2871	sodium ion transport
DXK01_RS18305	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DXK01_RS18315	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DXK01_RS18320	COG1805	sodium ion transport
DXK01_RS18325	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DXK01_RS18345	COG0784	Response regulator, receiver
DXK01_RS18345	COG2198	Histidine kinase
DXK01_RS18345	COG2205	protein histidine kinase activity
DXK01_RS18360	COG0612	Peptidase, M16
DXK01_RS18385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DXK01_RS18390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DXK01_RS18430	COG4206	TonB-dependent receptor
DXK01_RS18430	COG1629	transport
DXK01_RS18435	COG0488	(ABC) transporter
DXK01_RS18450	COG4974	Belongs to the 'phage' integrase family
DXK01_RS18460	COG2003	Belongs to the UPF0758 family
DXK01_RS18495	COG4584	PFAM Integrase catalytic
DXK01_RS18500	COG1484	DNA-dependent DNA replication
DXK01_RS18550	COG0793	Belongs to the peptidase S41A family
DXK01_RS18555	COG0534	Mate efflux family protein
DXK01_RS18565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DXK01_RS18600	COG1136	(ABC) transporter
DXK01_RS18605	COG1136	(ABC) transporter
DXK01_RS18605	COG0577	efflux transmembrane transporter activity
DXK01_RS18615	COG3279	Response regulator of the LytR AlgR family
DXK01_RS18630	COG0363	glucosamine-6-phosphate deaminase activity
DXK01_RS18635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DXK01_RS18640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DXK01_RS18650	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXK01_RS18655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXK01_RS18660	COG0318	PFAM AMP-dependent synthetase and ligase
DXK01_RS18665	COG3119	arylsulfatase activity
DXK01_RS18675	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DXK01_RS18700	COG0534	Mate efflux family protein
DXK01_RS18725	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS18725	COG4977	sequence-specific DNA binding
DXK01_RS18730	COG4771	TonB-dependent receptor
DXK01_RS18745	COG2205	protein histidine kinase activity
DXK01_RS18750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXK01_RS18770	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS18800	COG0110	maltose O-acetyltransferase activity
DXK01_RS18815	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS18875	COG2183	response to ionizing radiation
DXK01_RS18890	COG0488	(ABC) transporter
DXK01_RS18895	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DXK01_RS18900	COG0484	heat shock protein binding
DXK01_RS18910	COG1629	transport
DXK01_RS18910	COG4206	TonB-dependent receptor
DXK01_RS18930	COG3345	alpha-galactosidase
DXK01_RS18945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DXK01_RS18950	COG3250	beta-galactosidase activity
DXK01_RS18960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DXK01_RS18980	COG2755	lipolytic protein G-D-S-L family
DXK01_RS18980	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DXK01_RS19010	COG0702	epimerase
DXK01_RS19015	COG1629	transport
DXK01_RS19030	COG2814	Major facilitator Superfamily
DXK01_RS19040	COG1940	carbohydrate kinase activity
DXK01_RS19065	COG1086	Polysaccharide biosynthesis protein
DXK01_RS19075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DXK01_RS19085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DXK01_RS19085	COG0674	pyruvate-flavodoxin oxidoreductase activity
DXK01_RS19085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DXK01_RS19085	COG1013	pyruvate-flavodoxin oxidoreductase activity
DXK01_RS19090	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DXK01_RS19100	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DXK01_RS19105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DXK01_RS19110	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DXK01_RS19115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DXK01_RS19125	COG0242	peptide deformylase activity
DXK01_RS19130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DXK01_RS19140	COG2885	chlorophyll binding
DXK01_RS19165	COG2895	sulfate adenylyltransferase (ATP) activity
DXK01_RS19170	COG0175	sulfate reduction
DXK01_RS19175	COG0529	Catalyzes the synthesis of activated sulfate
DXK01_RS19180	COG3273	potassium ion transport
DXK01_RS19180	COG0471	metal ion transport
DXK01_RS19185	COG1218	3'(2'),5'-bisphosphate nucleotidase
DXK01_RS19190	COG3250	beta-galactosidase activity
DXK01_RS19195	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS19200	COG0702	epimerase
DXK01_RS19205	COG1629	transport
DXK01_RS19215	COG4771	TonB-dependent receptor
DXK01_RS19220	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19220	COG2205	protein histidine kinase activity
DXK01_RS19220	COG3292	Two component regulator propeller
DXK01_RS19235	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS19240	COG5492	domain, Protein
DXK01_RS19270	COG1482	cell wall glycoprotein biosynthetic process
DXK01_RS19285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DXK01_RS19290	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS19300	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS19305	COG3292	Two component regulator propeller
DXK01_RS19305	COG2205	protein histidine kinase activity
DXK01_RS19305	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19315	COG4206	TonB-dependent receptor
DXK01_RS19315	COG1629	transport
DXK01_RS19320	COG0702	epimerase
DXK01_RS19330	COG0702	epimerase
DXK01_RS19335	COG3507	Belongs to the glycosyl hydrolase 43 family
DXK01_RS19350	COG2816	NAD+ diphosphatase activity
DXK01_RS19360	COG2160	L-arabinose isomerase activity
DXK01_RS19385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DXK01_RS19390	COG0698	ribose 5-phosphate isomerase
DXK01_RS19435	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DXK01_RS19440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DXK01_RS19440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXK01_RS19455	COG1592	Rubrerythrin
DXK01_RS19455	COG1773	rubredoxin
DXK01_RS19480	COG0590	tRNA wobble adenosine to inosine editing
DXK01_RS19505	COG2264	protein methyltransferase activity
DXK01_RS19510	COG3757	hydrolase, family 25
DXK01_RS19530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DXK01_RS19535	COG2373	Large extracellular alpha-helical protein
DXK01_RS19540	COG4953	penicillin-binding protein 1C
DXK01_RS19545	COG0363	glucosamine-6-phosphate deaminase activity
DXK01_RS19555	COG1472	Belongs to the glycosyl hydrolase 3 family
DXK01_RS19560	COG3250	beta-galactosidase activity
DXK01_RS19565	COG4948	Mandelate Racemase Muconate Lactonizing
DXK01_RS19575	COG3292	Two component regulator propeller
DXK01_RS19575	COG2205	protein histidine kinase activity
DXK01_RS19575	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19575	COG3292	Two component regulator propeller
DXK01_RS19575	COG2205	protein histidine kinase activity
DXK01_RS19575	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19580	COG1609	Transcriptional regulator
DXK01_RS19585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS19595	COG1629	transport
DXK01_RS19595	COG4206	TonB-dependent receptor
DXK01_RS19645	COG1032	radical SAM domain protein
DXK01_RS19665	COG4206	TonB-dependent receptor
DXK01_RS19665	COG1629	transport
DXK01_RS19685	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19685	COG2205	protein histidine kinase activity
DXK01_RS19685	COG3292	Two component regulator propeller
DXK01_RS19690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DXK01_RS19695	COG0463	Glycosyl transferase, family 2
DXK01_RS19705	COG0646	methionine synthase
DXK01_RS19705	COG1410	methionine synthase
DXK01_RS19720	COG1408	metallophosphoesterase
DXK01_RS19805	COG0641	radical SAM
DXK01_RS19810	COG3591	Belongs to the peptidase S1B family
DXK01_RS19815	COG3591	Belongs to the peptidase S1B family
DXK01_RS19820	COG3118	belongs to the thioredoxin family
DXK01_RS19835	COG0488	(ABC) transporter
DXK01_RS19850	COG0745	RESPONSE REGULATOR receiver
DXK01_RS19855	COG5002	protein histidine kinase activity
DXK01_RS19875	COG3033	Beta-eliminating lyase
DXK01_RS19895	COG0629	single-stranded DNA binding
DXK01_RS19905	COG0776	regulation of translation
DXK01_RS19910	COG1530	ribonuclease E activity
DXK01_RS19915	COG1979	alcohol dehydrogenase
DXK01_RS19925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DXK01_RS19935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DXK01_RS19965	COG2204	response regulator
DXK01_RS19975	COG0131	Imidazoleglycerol-phosphate dehydratase
DXK01_RS19980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DXK01_RS19990	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DXK01_RS20005	COG3023	N-Acetylmuramoyl-L-alanine amidase
DXK01_RS20050	COG0584	glycerophosphoryl diester phosphodiesterase
DXK01_RS20080	COG1629	transport
DXK01_RS20125	COG4232	protein-disulfide reductase activity
DXK01_RS20135	COG0572	uridine kinase
DXK01_RS20140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DXK01_RS20145	COG0646	methionine synthase
DXK01_RS20145	COG1410	methionine synthase
DXK01_RS20150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DXK01_RS20185	COG4771	TonB-dependent receptor
DXK01_RS20195	COG1408	metallophosphoesterase
DXK01_RS20225	COG4452	Inner membrane protein CreD
DXK01_RS20255	COG1757	Na H antiporter
DXK01_RS20270	COG0482	sulfurtransferase activity
DXK01_RS20275	COG2873	o-acetylhomoserine
DXK01_RS20295	COG1253	flavin adenine dinucleotide binding
DXK01_RS20310	COG0582	viral genome integration into host DNA
DXK01_RS20345	COG3250	beta-galactosidase activity
DXK01_RS20355	COG4771	TonB-dependent receptor
DXK01_RS20360	COG0702	epimerase
DXK01_RS20380	COG1629	transport
DXK01_RS20385	COG0702	epimerase
DXK01_RS20435	COG0702	epimerase
DXK01_RS20440	COG4771	TonB-dependent receptor
DXK01_RS20460	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS20470	COG3250	beta-galactosidase activity
DXK01_RS20475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DXK01_RS20480	COG0745	RESPONSE REGULATOR receiver
DXK01_RS20480	COG3292	Two component regulator propeller
DXK01_RS20480	COG2205	protein histidine kinase activity
DXK01_RS20490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DXK01_RS20490	COG1333	cytochrome c biogenesis protein
DXK01_RS20495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DXK01_RS20520	COG2376	Dihydroxyacetone kinase
DXK01_RS20545	COG0745	RESPONSE REGULATOR receiver
DXK01_RS20545	COG3292	Two component regulator propeller
DXK01_RS20545	COG2205	protein histidine kinase activity
DXK01_RS20565	COG1082	Xylose isomerase domain protein TIM barrel
DXK01_RS20610	COG2195	Cleaves the N-terminal amino acid of tripeptides
DXK01_RS20625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DXK01_RS20635	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DXK01_RS20645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DXK01_RS20650	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS20655	COG0438	transferase activity, transferring glycosyl groups
DXK01_RS20710	COG0656	L-ascorbic acid biosynthetic process
DXK01_RS20720	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DXK01_RS20730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DXK01_RS20780	COG0668	transmembrane transport
DXK01_RS20800	COG0745	RESPONSE REGULATOR receiver
DXK01_RS20820	COG0671	phosphoesterase, PA-phosphatase related
DXK01_RS20830	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DXK01_RS20835	COG0586	Pfam SNARE associated Golgi protein
DXK01_RS20860	COG1119	ATPase activity
DXK01_RS20865	COG1523	belongs to the glycosyl hydrolase 13 family
DXK01_RS20870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DXK01_RS20895	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DXK01_RS20900	COG2814	Major facilitator Superfamily
DXK01_RS20905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DXK01_RS20910	COG0126	phosphoglycerate kinase activity
DXK01_RS20920	COG2066	Belongs to the glutaminase family
DXK01_RS20930	COG2234	aminopeptidase activity
DXK01_RS20935	COG0424	maF-like protein
DXK01_RS20940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DXK01_RS20955	COG0778	Nitroreductase
DXK01_RS20985	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DXK01_RS20990	COG4206	TonB-dependent receptor
DXK01_RS20990	COG1629	transport
DXK01_RS20995	COG3250	beta-galactosidase activity
DXK01_RS21010	COG2205	protein histidine kinase activity
DXK01_RS21020	COG3292	Two component regulator propeller
DXK01_RS21020	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21020	COG2205	protein histidine kinase activity
DXK01_RS21075	COG1609	Transcriptional regulator
DXK01_RS21085	COG1554	hydrolase, family 65, central catalytic
DXK01_RS21090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DXK01_RS21105	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DXK01_RS21140	COG3250	beta-galactosidase activity
DXK01_RS21145	COG3119	arylsulfatase activity
DXK01_RS21155	COG0702	epimerase
DXK01_RS21160	COG4206	TonB-dependent receptor
DXK01_RS21160	COG1629	transport
DXK01_RS21170	COG2205	protein histidine kinase activity
DXK01_RS21170	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21170	COG3292	Two component regulator propeller
DXK01_RS21175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DXK01_RS21190	COG1280	lysine exporter protein (LysE YggA)
DXK01_RS21210	COG3292	Two component regulator propeller
DXK01_RS21210	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21210	COG2205	protein histidine kinase activity
DXK01_RS21210	COG2205	protein histidine kinase activity
DXK01_RS21210	COG3292	Two component regulator propeller
DXK01_RS21210	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21225	COG1649	PFAM Uncharacterised BCR, COG1649
DXK01_RS21230	COG2198	Histidine kinase
DXK01_RS21230	COG2205	protein histidine kinase activity
DXK01_RS21230	COG0784	Response regulator, receiver
DXK01_RS21230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DXK01_RS21250	COG1966	Carbon starvation protein
DXK01_RS21255	COG1649	PFAM Uncharacterised BCR, COG1649
DXK01_RS21285	COG3292	Two component regulator propeller
DXK01_RS21285	COG2205	protein histidine kinase activity
DXK01_RS21285	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DXK01_RS21325	COG1621	beta-fructofuranosidase activity
DXK01_RS21330	COG4771	TonB-dependent receptor
DXK01_RS21365	COG2086	electron transfer activity
DXK01_RS21370	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DXK01_RS21390	COG0484	heat shock protein binding
DXK01_RS21410	COG0459	protein refolding
DXK01_RS21415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DXK01_RS21445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DXK01_RS21450	COG0735	belongs to the Fur family
DXK01_RS21470	COG0514	ATP-dependent DNA helicase (RecQ)
DXK01_RS21480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DXK01_RS21505	COG0066	3-isopropylmalate dehydratase activity
DXK01_RS21510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DXK01_RS21515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DXK01_RS21560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXK01_RS21560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DXK01_RS21605	COG4977	sequence-specific DNA binding
DXK01_RS21605	COG1917	Cupin 2, conserved barrel domain protein
DXK01_RS21635	COG2873	o-acetylhomoserine
DXK01_RS21705	COG1360	Flagellar Motor Protein
DXK01_RS21720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DXK01_RS21750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DXK01_RS21760	COG0194	GDP metabolic process
DXK01_RS21775	COG1704	LemA family
DXK01_RS21790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DXK01_RS21795	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DXK01_RS21800	COG4942	peptidase
DXK01_RS21805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DXK01_RS21810	COG0750	zinc metalloprotease
DXK01_RS21815	COG0673	inositol 2-dehydrogenase activity
DXK01_RS21820	COG0632	four-way junction helicase activity
DXK01_RS21835	COG0006	proline dipeptidase activity
DXK01_RS21845	COG1505	serine-type exopeptidase activity
DXK01_RS21870	COG4771	TonB-dependent receptor
DXK01_RS21880	COG4771	TonB-dependent receptor
DXK01_RS21905	COG0363	glucosamine-6-phosphate deaminase activity
DXK01_RS21915	COG0745	RESPONSE REGULATOR receiver
DXK01_RS21915	COG2205	protein histidine kinase activity
DXK01_RS21915	COG3292	Two component regulator propeller
DXK01_RS21925	COG1408	metallophosphoesterase
DXK01_RS21930	COG1575	Belongs to the MenA family. Type 1 subfamily
DXK01_RS21940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DXK01_RS21950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DXK01_RS21960	COG0617	tRNA 3'-terminal CCA addition
DXK01_RS21975	COG2204	response regulator
DXK01_RS21980	COG0488	(ABC) transporter
DXK01_RS21985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DXK01_RS22015	COG4206	TonB-dependent receptor
DXK01_RS22030	COG4139	cobalamin transport
DXK01_RS22035	COG1120	ATPase activity
DXK01_RS22040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DXK01_RS22040	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DXK01_RS22045	COG4771	TonB-dependent receptor
DXK01_RS22060	COG1595	DNA-templated transcription, initiation
DXK01_RS22070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DXK01_RS22075	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DXK01_RS22085	COG1522	sequence-specific DNA binding
DXK01_RS22120	COG0811	peptide transport
DXK01_RS22135	COG0084	hydrolase, TatD family'
DXK01_RS22160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DXK01_RS22165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DXK01_RS22170	COG0205	6-phosphofructokinase activity
DXK01_RS22190	COG0372	Belongs to the citrate synthase family
DXK01_RS22205	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DXK01_RS22215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DXK01_RS22225	COG0440	acetolactate synthase activity
DXK01_RS22230	COG0028	Belongs to the TPP enzyme family
DXK01_RS22240	COG1047	Peptidyl-prolyl cis-trans
DXK01_RS22245	COG3681	Belongs to the UPF0597 family
DXK01_RS22285	COG0551	DNA topoisomerase type I activity
DXK01_RS22285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone