locus-tag	class	description
DYI28_RS00005	COG1230	cation diffusion facilitator family transporter
DYI28_RS00010	COG2985	domain, Protein
DYI28_RS00010	COG0490	domain, Protein
DYI28_RS00020	COG4771	TonB-dependent receptor
DYI28_RS00030	COG4771	TonB-dependent receptor
DYI28_RS00040	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS00045	COG2375	cellular response to nickel ion
DYI28_RS00045	COG1132	(ABC) transporter
DYI28_RS00050	COG1132	(ABC) transporter
DYI28_RS00060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DYI28_RS00060	COG1333	cytochrome c biogenesis protein
DYI28_RS00085	COG3487	Iron-regulated protein
DYI28_RS00090	COG1730	sister chromatid segregation
DYI28_RS00105	COG0138	bifunctional purine biosynthesis protein purh
DYI28_RS00115	COG2197	response regulator
DYI28_RS00130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DYI28_RS00135	COG0745	RESPONSE REGULATOR receiver
DYI28_RS00145	COG0252	asparaginase activity
DYI28_RS00155	COG0159	tryptophan synthase activity
DYI28_RS00160	COG0135	phosphoribosylanthranilate isomerase activity
DYI28_RS00165	COG0134	indole-3-glycerol-phosphate synthase activity
DYI28_RS00170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYI28_RS00180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DYI28_RS00185	COG0133	tryptophan synthase activity
DYI28_RS00200	COG1979	alcohol dehydrogenase
DYI28_RS00205	COG0784	Response regulator, receiver
DYI28_RS00205	COG2205	protein histidine kinase activity
DYI28_RS00210	COG0471	metal ion transport
DYI28_RS00210	COG0490	domain, Protein
DYI28_RS00230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DYI28_RS00245	COG0004	ammonium transporteR
DYI28_RS00250	COG0347	Belongs to the P(II) protein family
DYI28_RS00260	COG0436	Aminotransferase
DYI28_RS00265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DYI28_RS00285	COG0367	asparagine synthase
DYI28_RS00295	COG0067	glutamate synthase
DYI28_RS00295	COG0069	glutamate synthase activity
DYI28_RS00295	COG0070	glutamate synthase
DYI28_RS00300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYI28_RS00310	COG0505	Belongs to the CarA family
DYI28_RS00315	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DYI28_RS00330	COG2207	Transcriptional regulator
DYI28_RS00330	COG1917	Cupin 2, conserved barrel domain protein
DYI28_RS00340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYI28_RS00345	COG1131	(ABC) transporter
DYI28_RS00350	COG0842	Transport permease protein
DYI28_RS00355	COG0842	Transport permease protein
DYI28_RS00365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DYI28_RS00375	COG2949	membrane
DYI28_RS00395	COG0556	nucleotide-excision repair
DYI28_RS00400	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DYI28_RS00430	COG1388	LysM domain
DYI28_RS00430	COG3942	CHAP domain
DYI28_RS00440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYI28_RS00460	COG1983	PspC domain protein
DYI28_RS00475	COG0823	Involved in the tonB-independent uptake of proteins
DYI28_RS00475	COG1506	peptidase
DYI28_RS00480	COG0534	Mate efflux family protein
DYI28_RS00485	COG0706	membrane insertase activity
DYI28_RS00490	COG0504	CTP synthase activity
DYI28_RS00545	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS00550	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYI28_RS00625	COG4656	Part of a membrane complex involved in electron transport
DYI28_RS00630	COG4658	electron transport chain
DYI28_RS00635	COG4659	FMN binding
DYI28_RS00640	COG4660	Part of a membrane complex involved in electron transport
DYI28_RS00645	COG4657	Part of a membrane complex involved in electron transport
DYI28_RS00650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYI28_RS00655	COG4680	protein conserved in bacteria
DYI28_RS00665	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DYI28_RS00670	COG0305	Participates in initiation and elongation during chromosome replication
DYI28_RS00675	COG0072	phenylalanine-tRNA ligase activity
DYI28_RS00675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI28_RS00680	COG0217	transcriptional regulatory protein
DYI28_RS00695	COG0708	Exodeoxyribonuclease III
DYI28_RS00700	COG0432	Pfam Uncharacterised protein family UPF0047
DYI28_RS00720	COG0481	GTPase activity
DYI28_RS00730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DYI28_RS00740	COG0024	Methionine aminopeptidase
DYI28_RS00760	COG0564	pseudouridine synthase activity
DYI28_RS00765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYI28_RS00775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYI28_RS00775	COG0574	Belongs to the PEP-utilizing enzyme family
DYI28_RS00790	COG0352	thiamine-phosphate diphosphorylase activity
DYI28_RS00795	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DYI28_RS00805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DYI28_RS00810	COG2022	thiamine diphosphate biosynthetic process
DYI28_RS00815	COG0352	thiamine-phosphate diphosphorylase activity
DYI28_RS00825	COG5002	protein histidine kinase activity
DYI28_RS00905	COG3118	belongs to the thioredoxin family
DYI28_RS00925	COG5002	protein histidine kinase activity
DYI28_RS00930	COG0745	RESPONSE REGULATOR receiver
DYI28_RS00935	COG1082	Xylose isomerase domain protein TIM barrel
DYI28_RS00940	COG0318	PFAM AMP-dependent synthetase and ligase
DYI28_RS00950	COG2233	PERMEase
DYI28_RS00955	COG1151	hydroxylamine reductase activity
DYI28_RS00965	COG4191	Histidine kinase
DYI28_RS00970	COG2204	response regulator
DYI28_RS00990	COG0577	efflux transmembrane transporter activity
DYI28_RS00990	COG1136	(ABC) transporter
DYI28_RS01000	COG0534	Mate efflux family protein
DYI28_RS01005	COG1011	Hydrolase
DYI28_RS01010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DYI28_RS01020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYI28_RS01045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DYI28_RS01045	COG2755	lipolytic protein G-D-S-L family
DYI28_RS01050	COG0454	-acetyltransferase
DYI28_RS01055	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DYI28_RS01060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DYI28_RS01065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DYI28_RS01075	COG0356	it plays a direct role in the translocation of protons across the membrane
DYI28_RS01080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYI28_RS01085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DYI28_RS01090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYI28_RS01095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DYI28_RS01100	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DYI28_RS01105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYI28_RS01110	COG2431	L-lysine efflux transmembrane transporter activity
DYI28_RS01120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYI28_RS01120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI28_RS01125	COG1690	Belongs to the RtcB family
DYI28_RS01140	COG2207	Transcriptional regulator
DYI28_RS01185	COG2985	domain, Protein
DYI28_RS01190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DYI28_RS01195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYI28_RS01210	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DYI28_RS01215	COG0540	Belongs to the ATCase OTCase family
DYI28_RS01235	COG4974	Belongs to the 'phage' integrase family
DYI28_RS01255	COG1215	transferase activity, transferring glycosyl groups
DYI28_RS01270	COG5039	Polysaccharide pyruvyl transferase
DYI28_RS01275	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS01280	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DYI28_RS01295	COG0110	maltose O-acetyltransferase activity
DYI28_RS01305	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS01365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DYI28_RS01375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DYI28_RS01390	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYI28_RS01395	COG2205	protein histidine kinase activity
DYI28_RS01420	COG1629	transport
DYI28_RS01420	COG4206	TonB-dependent receptor
DYI28_RS01425	COG0702	epimerase
DYI28_RS01430	COG3119	arylsulfatase activity
DYI28_RS01435	COG3250	beta-galactosidase activity
DYI28_RS01440	COG2205	protein histidine kinase activity
DYI28_RS01445	COG1360	Flagellar Motor Protein
DYI28_RS01530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DYI28_RS01710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYI28_RS01725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DYI28_RS01745	COG0348	domain, Protein
DYI28_RS01750	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYI28_RS01765	COG2326	polyphosphate kinase activity
DYI28_RS01775	COG0667	Aldo Keto reductase
DYI28_RS01810	COG3279	Response regulator of the LytR AlgR family
DYI28_RS01815	COG0724	RNA recognition motif
DYI28_RS01825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DYI28_RS01830	COG0045	succinate-CoA ligase (ADP-forming) activity
DYI28_RS01840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYI28_RS01845	COG0351	phosphomethylpyrimidine kinase
DYI28_RS01860	COG2115	Belongs to the xylose isomerase family
DYI28_RS01865	COG2814	Major facilitator Superfamily
DYI28_RS01865	COG0477	Major facilitator Superfamily
DYI28_RS01875	COG3153	acetyltransferase
DYI28_RS01875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYI28_RS01885	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYI28_RS01895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DYI28_RS01910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYI28_RS01935	COG3015	lipoprotein NlpE involved in copper resistance
DYI28_RS01955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DYI28_RS01970	COG4974	Belongs to the 'phage' integrase family
DYI28_RS02050	COG0587	DNA-directed DNA polymerase activity
DYI28_RS02055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYI28_RS02065	COG0587	DNA-directed DNA polymerase activity
DYI28_RS02120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYI28_RS02120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYI28_RS02305	COG0756	dUTP diphosphatase activity
DYI28_RS02310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYI28_RS02685	COG1904	glucuronate isomerase
DYI28_RS02690	COG1609	Transcriptional regulator
DYI28_RS02695	COG0246	Mannitol dehydrogenase
DYI28_RS02725	COG0513	Belongs to the DEAD box helicase family
DYI28_RS02730	COG3830	Belongs to the UPF0237 family
DYI28_RS02730	COG0560	Phosphoserine phosphatase
DYI28_RS02755	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYI28_RS02760	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DYI28_RS02860	COG0616	signal peptide processing
DYI28_RS03040	COG2205	protein histidine kinase activity
DYI28_RS03045	COG2204	response regulator
DYI28_RS03070	COG0577	efflux transmembrane transporter activity
DYI28_RS03070	COG1136	(ABC) transporter
DYI28_RS03085	COG0156	8-amino-7-oxononanoate synthase activity
DYI28_RS03090	COG1597	lipid kinase activity
DYI28_RS03095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DYI28_RS03130	COG1132	(ABC) transporter
DYI28_RS03150	COG1595	DNA-templated transcription, initiation
DYI28_RS03155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DYI28_RS03165	COG1538	Outer membrane efflux protein
DYI28_RS03170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYI28_RS03185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYI28_RS03200	COG0543	2 iron, 2 sulfur cluster binding
DYI28_RS03205	COG0167	dihydroorotate dehydrogenase activity
DYI28_RS03210	COG0336	Belongs to the RNA methyltransferase TrmD family
DYI28_RS03215	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYI28_RS03220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYI28_RS03260	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI28_RS03265	COG0326	Molecular chaperone. Has ATPase activity
DYI28_RS03315	COG2304	oxidoreductase activity
DYI28_RS03330	COG0714	Associated with various cellular activities
DYI28_RS03340	COG0776	regulation of translation
DYI28_RS03345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYI28_RS03350	COG0552	protein localization to endoplasmic reticulum
DYI28_RS03360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DYI28_RS03365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DYI28_RS03375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DYI28_RS03410	COG2205	protein histidine kinase activity
DYI28_RS03415	COG0745	RESPONSE REGULATOR receiver
DYI28_RS03420	COG0442	prolyl-tRNA aminoacylation
DYI28_RS03455	COG3292	Two component regulator propeller
DYI28_RS03455	COG2205	protein histidine kinase activity
DYI28_RS03455	COG0745	RESPONSE REGULATOR receiver
DYI28_RS03455	COG2205	protein histidine kinase activity
DYI28_RS03455	COG3292	Two component regulator propeller
DYI28_RS03455	COG0745	RESPONSE REGULATOR receiver
DYI28_RS03470	COG4206	TonB-dependent receptor
DYI28_RS03510	COG1733	regulation of RNA biosynthetic process
DYI28_RS03535	COG1011	Hydrolase
DYI28_RS03540	COG0300	oxidoreductase activity
DYI28_RS03555	COG2966	Psort location CytoplasmicMembrane, score
DYI28_RS03570	COG4206	TonB-dependent receptor
DYI28_RS03570	COG1629	transport
DYI28_RS03585	COG3537	Alpha-1,2-mannosidase
DYI28_RS03590	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DYI28_RS03625	COG1629	transport
DYI28_RS03625	COG4206	TonB-dependent receptor
DYI28_RS03640	COG1629	transport
DYI28_RS03640	COG4206	TonB-dependent receptor
DYI28_RS03680	COG1074	ATP-dependent DNA helicase activity
DYI28_RS03700	COG0745	RESPONSE REGULATOR receiver
DYI28_RS03770	COG1475	DNA binding
DYI28_RS03775	COG3969	phosphoadenosine phosphosulfate
DYI28_RS03795	COG0305	Participates in initiation and elongation during chromosome replication
DYI28_RS03800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYI28_RS03815	COG1678	Uncharacterized ACR, COG1678
DYI28_RS03830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DYI28_RS03840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DYI28_RS03860	COG2755	lipolytic protein G-D-S-L family
DYI28_RS03860	COG0657	acetylesterase activity
DYI28_RS03870	COG0321	lipoyl(octanoyl) transferase activity
DYI28_RS03880	COG2217	Heavy metal translocating P-type atpase
DYI28_RS03900	COG1408	metallophosphoesterase
DYI28_RS03915	COG0357	Ribosomal RNA small subunit methyltransferase G
DYI28_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYI28_RS03925	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYI28_RS03925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DYI28_RS03930	COG0778	Nitroreductase
DYI28_RS03945	COG1739	Uncharacterized protein family UPF0029
DYI28_RS03960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DYI28_RS03965	COG0513	Belongs to the DEAD box helicase family
DYI28_RS03980	COG2871	sodium ion transport
DYI28_RS03995	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DYI28_RS04000	COG1805	sodium ion transport
DYI28_RS04005	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DYI28_RS04055	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS04095	COG1024	Enoyl-CoA hydratase
DYI28_RS04095	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYI28_RS04100	COG2244	polysaccharide biosynthetic process
DYI28_RS04105	COG1442	glycosyl transferase family 8
DYI28_RS04115	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS04135	COG2205	protein histidine kinase activity
DYI28_RS04135	COG0784	Response regulator, receiver
DYI28_RS04155	COG0488	(ABC) transporter
DYI28_RS04170	COG4974	Belongs to the 'phage' integrase family
DYI28_RS04180	COG2003	Belongs to the UPF0758 family
DYI28_RS04190	COG0582	viral genome integration into host DNA
DYI28_RS04360	COG2815	serine threonine protein kinase
DYI28_RS04360	COG0515	serine threonine protein kinase
DYI28_RS04375	COG0551	DNA topoisomerase type I activity
DYI28_RS04375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS04430	COG3177	Filamentation induced by cAMP protein fic
DYI28_RS04440	COG4974	Belongs to the 'phage' integrase family
DYI28_RS04545	COG3344	reverse transcriptase
DYI28_RS04615	COG1475	DNA binding
DYI28_RS04620	COG3969	phosphoadenosine phosphosulfate
DYI28_RS04685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS04685	COG0551	DNA topoisomerase type I activity
DYI28_RS04800	COG2205	protein histidine kinase activity
DYI28_RS04800	COG0784	Response regulator, receiver
DYI28_RS04805	COG2755	lipolytic protein G-D-S-L family
DYI28_RS04805	COG0657	acetylesterase activity
DYI28_RS04810	COG0534	Mate efflux family protein
DYI28_RS04815	COG2885	chlorophyll binding
DYI28_RS04820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYI28_RS04830	COG1704	LemA family
DYI28_RS04835	COG0501	Belongs to the peptidase M48B family
DYI28_RS04865	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYI28_RS04870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYI28_RS04895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYI28_RS04900	COG1136	(ABC) transporter
DYI28_RS04905	COG0577	efflux transmembrane transporter activity
DYI28_RS04905	COG1136	(ABC) transporter
DYI28_RS04915	COG3279	Response regulator of the LytR AlgR family
DYI28_RS04925	COG2837	iron assimilation
DYI28_RS04930	COG0363	glucosamine-6-phosphate deaminase activity
DYI28_RS04935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DYI28_RS04940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DYI28_RS04945	COG1301	dicarboxylic acid transport
DYI28_RS04950	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DYI28_RS04955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI28_RS04960	COG1022	Amp-dependent synthetase and ligase
DYI28_RS04970	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
DYI28_RS04975	COG0490	domain, Protein
DYI28_RS04975	COG2985	domain, Protein
DYI28_RS04990	COG2425	protein containing a von Willebrand factor type A (vWA) domain
DYI28_RS05265	COG0737	Belongs to the 5'-nucleotidase family
DYI28_RS05270	COG2205	protein histidine kinase activity
DYI28_RS05270	COG2202	Pas domain
DYI28_RS05275	COG2183	response to ionizing radiation
DYI28_RS05310	COG0488	(ABC) transporter
DYI28_RS05315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYI28_RS05320	COG0484	heat shock protein binding
DYI28_RS05325	COG0393	Putative heavy-metal-binding
DYI28_RS05330	COG4335	DNA alkylation repair
DYI28_RS05335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS05340	COG4771	TonB-dependent receptor
DYI28_RS05345	COG4974	Belongs to the 'phage' integrase family
DYI28_RS05375	COG2204	response regulator
DYI28_RS05475	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS05475	COG0551	DNA topoisomerase type I activity
DYI28_RS05545	COG4974	Belongs to the 'phage' integrase family
DYI28_RS05550	COG4974	Belongs to the 'phage' integrase family
DYI28_RS05610	COG1192	Involved in chromosome partitioning
DYI28_RS05705	COG0358	DNA primase activity
DYI28_RS05750	COG0484	heat shock protein binding
DYI28_RS05820	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS05825	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS05850	COG1629	transport
DYI28_RS05880	COG1649	PFAM Uncharacterised BCR, COG1649
DYI28_RS05885	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS05900	COG1082	Xylose isomerase domain protein TIM barrel
DYI28_RS05960	COG1629	transport
DYI28_RS05970	COG2814	Major facilitator Superfamily
DYI28_RS05985	COG1940	carbohydrate kinase activity
DYI28_RS06000	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYI28_RS06010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DYI28_RS06020	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYI28_RS06020	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYI28_RS06020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYI28_RS06020	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYI28_RS06025	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DYI28_RS06030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYI28_RS06040	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DYI28_RS06045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DYI28_RS06050	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DYI28_RS06055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DYI28_RS06065	COG0242	peptide deformylase activity
DYI28_RS06070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DYI28_RS06090	COG2895	sulfate adenylyltransferase (ATP) activity
DYI28_RS06095	COG0175	sulfate reduction
DYI28_RS06100	COG0529	Catalyzes the synthesis of activated sulfate
DYI28_RS06105	COG0471	metal ion transport
DYI28_RS06105	COG3273	potassium ion transport
DYI28_RS06110	COG1218	3'(2'),5'-bisphosphate nucleotidase
DYI28_RS06120	COG4221	oxidoreductase activity
DYI28_RS06155	COG0463	Glycosyl transferase, family 2
DYI28_RS06160	COG0110	maltose O-acetyltransferase activity
DYI28_RS06165	COG0297	glycogen (starch) synthase activity
DYI28_RS06205	COG1216	Glycosyl transferase, family 2
DYI28_RS06230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYI28_RS06250	COG1216	Glycosyl transferase, family 2
DYI28_RS06315	COG4974	Belongs to the 'phage' integrase family
DYI28_RS06320	COG1482	cell wall glycoprotein biosynthetic process
DYI28_RS06335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DYI28_RS06370	COG2816	NAD+ diphosphatase activity
DYI28_RS06380	COG2160	L-arabinose isomerase activity
DYI28_RS06385	COG1070	Carbohydrate kinase
DYI28_RS06400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYI28_RS06405	COG0698	ribose 5-phosphate isomerase
DYI28_RS06410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DYI28_RS06425	COG5012	cobalamin binding
DYI28_RS06430	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS06475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS06490	COG4771	TonB-dependent receptor
DYI28_RS06540	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DYI28_RS06550	COG0673	inositol 2-dehydrogenase activity
DYI28_RS06555	COG0590	tRNA wobble adenosine to inosine editing
DYI28_RS06575	COG2264	protein methyltransferase activity
DYI28_RS06585	COG0022	dehydrogenase e1 component
DYI28_RS06590	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYI28_RS06630	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI28_RS06650	COG4974	Belongs to the 'phage' integrase family
DYI28_RS06670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYI28_RS06675	COG0363	glucosamine-6-phosphate deaminase activity
DYI28_RS06695	COG1032	radical SAM domain protein
DYI28_RS06700	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DYI28_RS06705	COG0463	Glycosyl transferase, family 2
DYI28_RS06710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DYI28_RS06715	COG0646	methionine synthase
DYI28_RS06715	COG1410	methionine synthase
DYI28_RS06735	COG0420	3'-5' exonuclease activity
DYI28_RS06760	COG0641	radical SAM
DYI28_RS06765	COG3591	Belongs to the peptidase S1B family
DYI28_RS06770	COG3591	Belongs to the peptidase S1B family
DYI28_RS06785	COG3118	belongs to the thioredoxin family
DYI28_RS06800	COG1773	rubredoxin
DYI28_RS06800	COG1592	Rubrerythrin
DYI28_RS06820	COG1404	Belongs to the peptidase S8 family
DYI28_RS06850	COG4206	TonB-dependent receptor
DYI28_RS06850	COG1629	transport
DYI28_RS06855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYI28_RS06855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYI28_RS06865	COG0131	Imidazoleglycerol-phosphate dehydratase
DYI28_RS06870	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYI28_RS06875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYI28_RS06880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYI28_RS06905	COG2271	Major facilitator Superfamily
DYI28_RS06930	COG0702	epimerase
DYI28_RS06935	COG4771	TonB-dependent receptor
DYI28_RS06950	COG1741	Belongs to the pirin family
DYI28_RS06955	COG4232	protein-disulfide reductase activity
DYI28_RS06965	COG0572	uridine kinase
DYI28_RS06970	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
DYI28_RS06975	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYI28_RS06980	COG0778	Nitroreductase
DYI28_RS06985	COG0646	methionine synthase
DYI28_RS06985	COG1410	methionine synthase
DYI28_RS06990	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DYI28_RS07045	COG0545	Peptidyl-prolyl cis-trans isomerase
DYI28_RS07050	COG2373	Large extracellular alpha-helical protein
DYI28_RS07055	COG4953	penicillin-binding protein 1C
DYI28_RS07060	COG2814	Major facilitator Superfamily
DYI28_RS07070	COG1757	Na H antiporter
DYI28_RS07080	COG2197	response regulator
DYI28_RS07090	COG0482	sulfurtransferase activity
DYI28_RS07095	COG0793	Belongs to the peptidase S41A family
DYI28_RS07115	COG0501	Belongs to the peptidase M48B family
DYI28_RS07120	COG1253	flavin adenine dinucleotide binding
DYI28_RS07135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS07155	COG0702	epimerase
DYI28_RS07160	COG1629	transport
DYI28_RS07175	COG4974	Belongs to the 'phage' integrase family
DYI28_RS07275	COG4474	Belongs to the UPF0398 family
DYI28_RS07280	COG1475	DNA binding
DYI28_RS07300	COG2003	Belongs to the UPF0758 family
DYI28_RS07490	COG4974	Belongs to the 'phage' integrase family
DYI28_RS07500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS07500	COG0551	DNA topoisomerase type I activity
DYI28_RS07575	COG3250	beta-galactosidase activity
DYI28_RS07595	COG4206	TonB-dependent receptor
DYI28_RS07595	COG1629	transport
DYI28_RS07645	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS07650	COG2207	Transcriptional regulator
DYI28_RS07650	COG0662	Cupin 2, conserved barrel domain protein
DYI28_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS07690	COG0561	phosphatase activity
DYI28_RS07695	COG1629	transport
DYI28_RS07700	COG1595	DNA-templated transcription, initiation
DYI28_RS07710	COG3292	Two component regulator propeller
DYI28_RS07710	COG2205	protein histidine kinase activity
DYI28_RS07710	COG0745	RESPONSE REGULATOR receiver
DYI28_RS07750	COG4974	Belongs to the 'phage' integrase family
DYI28_RS07805	COG0202	RNA polymerase activity
DYI28_RS07945	COG1475	DNA binding
DYI28_RS07965	COG1192	Involved in chromosome partitioning
DYI28_RS07985	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DYI28_RS08000	COG0629	single-stranded DNA binding
DYI28_RS08060	COG2197	response regulator
DYI28_RS08065	COG0739	heme binding
DYI28_RS08065	COG1196	nuclear chromosome segregation
DYI28_RS08065	COG0741	lytic transglycosylase activity
DYI28_RS08130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYI28_RS08135	COG1388	LysM domain
DYI28_RS08135	COG1705	Flagellar rod assembly protein muramidase FlgJ
DYI28_RS08250	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS08315	COG2755	lipolytic protein G-D-S-L family
DYI28_RS08315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DYI28_RS08525	COG0784	Response regulator, receiver
DYI28_RS08525	COG2205	protein histidine kinase activity
DYI28_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS08535	COG1312	Catalyzes the dehydration of D-mannonate
DYI28_RS08545	COG3250	beta-galactosidase activity
DYI28_RS08555	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS08560	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS08565	COG1629	transport
DYI28_RS08565	COG4206	TonB-dependent receptor
DYI28_RS08575	COG3292	Two component regulator propeller
DYI28_RS08575	COG0745	RESPONSE REGULATOR receiver
DYI28_RS08575	COG2205	protein histidine kinase activity
DYI28_RS08580	COG3328	transposase activity
DYI28_RS08590	COG3250	beta-galactosidase activity
DYI28_RS08600	COG2755	lipolytic protein G-D-S-L family
DYI28_RS08610	COG4771	TonB-dependent receptor
DYI28_RS08625	COG3292	Two component regulator propeller
DYI28_RS08625	COG2205	protein histidine kinase activity
DYI28_RS08625	COG0745	RESPONSE REGULATOR receiver
DYI28_RS08645	COG1475	DNA binding
DYI28_RS08725	COG3344	reverse transcriptase
DYI28_RS08870	COG1431	PFAM Stem cell self-renewal protein Piwi
DYI28_RS08880	COG4974	Belongs to the 'phage' integrase family
DYI28_RS08895	COG4974	Belongs to the 'phage' integrase family
DYI28_RS08980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS08980	COG0551	DNA topoisomerase type I activity
DYI28_RS09170	COG4974	Belongs to the 'phage' integrase family
DYI28_RS09180	COG1882	Formate acetyltransferase
DYI28_RS09185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DYI28_RS09190	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS09235	COG2271	Major facilitator Superfamily
DYI28_RS09240	COG0584	glycerophosphoryl diester phosphodiesterase
DYI28_RS09250	COG0584	glycerophosphoryl diester phosphodiesterase
DYI28_RS09260	COG4771	TonB-dependent receptor
DYI28_RS09270	COG1595	DNA-templated transcription, initiation
DYI28_RS09290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DYI28_RS09300	COG0783	Belongs to the Dps family
DYI28_RS09320	COG4206	TonB-dependent receptor
DYI28_RS09320	COG1629	transport
DYI28_RS09335	COG1191	sigma factor activity
DYI28_RS09345	COG0577	efflux transmembrane transporter activity
DYI28_RS09345	COG1136	(ABC) transporter
DYI28_RS09350	COG0577	efflux transmembrane transporter activity
DYI28_RS09350	COG1136	(ABC) transporter
DYI28_RS09370	COG3852	Histidine kinase
DYI28_RS09375	COG0628	permease
DYI28_RS09380	COG1215	transferase activity, transferring glycosyl groups
DYI28_RS09385	COG0456	acetyltransferase
DYI28_RS09390	COG0189	ligase activity
DYI28_RS09390	COG0569	domain protein
DYI28_RS09395	COG0577	efflux transmembrane transporter activity
DYI28_RS09395	COG1136	(ABC) transporter
DYI28_RS09400	COG0436	Aminotransferase
DYI28_RS09420	COG0488	(ABC) transporter
DYI28_RS09435	COG0745	RESPONSE REGULATOR receiver
DYI28_RS09455	COG4206	TonB-dependent receptor
DYI28_RS09475	COG3033	Beta-eliminating lyase
DYI28_RS09500	COG0629	single-stranded DNA binding
DYI28_RS09505	COG1194	a g-specific adenine glycosylase
DYI28_RS09515	COG1530	ribonuclease E activity
DYI28_RS09585	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS09620	COG4771	TonB-dependent receptor
DYI28_RS09625	COG1979	alcohol dehydrogenase
DYI28_RS09640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DYI28_RS09650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DYI28_RS09665	COG4191	Histidine kinase
DYI28_RS09670	COG2204	response regulator
DYI28_RS09690	COG0577	efflux transmembrane transporter activity
DYI28_RS09710	COG1136	(ABC) transporter
DYI28_RS09720	COG1252	NADH dehydrogenase
DYI28_RS09725	COG1705	Flagellar rod assembly protein muramidase FlgJ
DYI28_RS09730	COG0295	cytidine deaminase activity
DYI28_RS09740	COG3059	membrane
DYI28_RS09745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYI28_RS09750	COG0488	(ABC) transporter
DYI28_RS09780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYI28_RS09800	COG1629	transport
DYI28_RS09800	COG4206	TonB-dependent receptor
DYI28_RS09815	COG0686	Belongs to the AlaDH PNT family
DYI28_RS09855	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DYI28_RS09875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYI28_RS09880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DYI28_RS09895	COG1595	DNA-templated transcription, initiation
DYI28_RS09930	COG0702	epimerase
DYI28_RS09935	COG1629	transport
DYI28_RS09955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYI28_RS09960	COG1741	Belongs to the pirin family
DYI28_RS09965	COG0259	pyridoxamine-phosphate oxidase activity
DYI28_RS09980	COG0346	lactoylglutathione lyase activity
DYI28_RS10010	COG0784	Response regulator, receiver
DYI28_RS10010	COG2205	protein histidine kinase activity
DYI28_RS10030	COG1918	ferrous iron import across plasma membrane
DYI28_RS10030	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DYI28_RS10035	COG0037	tRNA processing
DYI28_RS10050	COG3119	arylsulfatase activity
DYI28_RS10055	COG2205	protein histidine kinase activity
DYI28_RS10055	COG2202	Pas domain
DYI28_RS10060	COG2205	protein histidine kinase activity
DYI28_RS10060	COG2202	Pas domain
DYI28_RS10065	COG0534	Mate efflux family protein
DYI28_RS10070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYI28_RS10075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYI28_RS10120	COG2003	Belongs to the UPF0758 family
DYI28_RS10200	COG0582	viral genome integration into host DNA
DYI28_RS10220	COG0582	viral genome integration into host DNA
DYI28_RS10245	COG1983	PspC domain protein
DYI28_RS10250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DYI28_RS10275	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYI28_RS10325	COG0668	transmembrane transport
DYI28_RS10335	COG3250	beta-galactosidase activity
DYI28_RS10340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS10345	COG3119	arylsulfatase activity
DYI28_RS10360	COG1629	transport
DYI28_RS10360	COG4206	TonB-dependent receptor
DYI28_RS10390	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYI28_RS10400	COG0745	RESPONSE REGULATOR receiver
DYI28_RS10400	COG3292	Two component regulator propeller
DYI28_RS10400	COG2205	protein histidine kinase activity
DYI28_RS10400	COG3292	Two component regulator propeller
DYI28_RS10400	COG0745	RESPONSE REGULATOR receiver
DYI28_RS10400	COG2205	protein histidine kinase activity
DYI28_RS10405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYI28_RS10410	COG1830	Aldolase
DYI28_RS10415	COG0588	phosphoglycerate mutase activity
DYI28_RS10430	COG4206	TonB-dependent receptor
DYI28_RS10430	COG1629	transport
DYI28_RS10450	COG1119	ATPase activity
DYI28_RS10455	COG3661	Belongs to the glycosyl hydrolase 67 family
DYI28_RS10470	COG2211	Major facilitator Superfamily
DYI28_RS10490	COG0561	phosphatase activity
DYI28_RS10495	COG4206	TonB-dependent receptor
DYI28_RS10495	COG1629	transport
DYI28_RS10505	COG1523	belongs to the glycosyl hydrolase 13 family
DYI28_RS10510	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DYI28_RS10555	COG4717	serine-type aminopeptidase activity
DYI28_RS10585	COG4974	Belongs to the 'phage' integrase family
DYI28_RS10625	COG0551	DNA topoisomerase type I activity
DYI28_RS10625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS10660	COG0784	Response regulator, receiver
DYI28_RS10660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYI28_RS10660	COG2198	Histidine kinase
DYI28_RS10660	COG2205	protein histidine kinase activity
DYI28_RS10790	COG0358	DNA primase activity
DYI28_RS10865	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DYI28_RS10875	COG2814	Major facilitator Superfamily
DYI28_RS10880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DYI28_RS10885	COG0126	phosphoglycerate kinase activity
DYI28_RS10900	COG2311	Membrane
DYI28_RS10910	COG0424	maF-like protein
DYI28_RS10930	COG0778	Nitroreductase
DYI28_RS10940	COG0288	reversible hydration of carbon dioxide
DYI28_RS10950	COG1629	transport
DYI28_RS10965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI28_RS10975	COG0511	ligase activity, forming carbon-carbon bonds
DYI28_RS10980	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DYI28_RS10990	COG0191	fructose-bisphosphate aldolase activity
DYI28_RS10995	COG0254	rRNA binding
DYI28_RS11000	COG1373	ATPase (AAA superfamily
DYI28_RS11020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYI28_RS11045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DYI28_RS11050	COG0511	ligase activity, forming carbon-carbon bonds
DYI28_RS11070	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DYI28_RS11085	COG1280	lysine exporter protein (LysE YggA)
DYI28_RS11095	COG0745	RESPONSE REGULATOR receiver
DYI28_RS11095	COG3292	Two component regulator propeller
DYI28_RS11095	COG2205	protein histidine kinase activity
DYI28_RS11095	COG3292	Two component regulator propeller
DYI28_RS11095	COG0745	RESPONSE REGULATOR receiver
DYI28_RS11095	COG2205	protein histidine kinase activity
DYI28_RS11110	COG1649	PFAM Uncharacterised BCR, COG1649
DYI28_RS11130	COG1966	Carbon starvation protein
DYI28_RS11135	COG1649	PFAM Uncharacterised BCR, COG1649
DYI28_RS11155	COG2113	Glycine betaine
DYI28_RS11160	COG4176	ABC-type proline glycine betaine transport system permease component
DYI28_RS11170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DYI28_RS11180	COG2205	protein histidine kinase activity
DYI28_RS11180	COG3292	Two component regulator propeller
DYI28_RS11180	COG0745	RESPONSE REGULATOR receiver
DYI28_RS11185	COG1629	transport
DYI28_RS11185	COG4206	TonB-dependent receptor
DYI28_RS11200	COG1621	beta-fructofuranosidase activity
DYI28_RS11215	COG0561	phosphatase activity
DYI28_RS11220	COG1629	transport
DYI28_RS11220	COG4206	TonB-dependent receptor
DYI28_RS11235	COG1621	beta-fructofuranosidase activity
DYI28_RS11245	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYI28_RS11250	COG0475	glutathione-regulated potassium exporter activity
DYI28_RS11285	COG3279	Response regulator of the LytR AlgR family
DYI28_RS11350	COG4772	TonB-dependent receptor
DYI28_RS11375	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DYI28_RS11380	COG1960	acyl-CoA dehydrogenase activity
DYI28_RS11385	COG0705	Rhomboid family
DYI28_RS11400	COG1956	GAF domain-containing protein
DYI28_RS11410	COG0484	heat shock protein binding
DYI28_RS11415	COG2194	sulfuric ester hydrolase activity
DYI28_RS11435	COG0028	Belongs to the TPP enzyme family
DYI28_RS11475	COG0459	protein refolding
DYI28_RS11480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DYI28_RS11505	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYI28_RS11515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DYI28_RS11520	COG0124	histidyl-tRNA synthetase
DYI28_RS11535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYI28_RS11560	COG0514	ATP-dependent DNA helicase (RecQ)
DYI28_RS11570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYI28_RS11575	COG1368	sulfuric ester hydrolase activity
DYI28_RS11580	COG0671	phosphoesterase, PA-phosphatase related
DYI28_RS11585	COG0473	3-isopropylmalate dehydrogenase activity
DYI28_RS11595	COG0066	3-isopropylmalate dehydratase activity
DYI28_RS11600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYI28_RS11605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYI28_RS11650	COG4977	sequence-specific DNA binding
DYI28_RS11650	COG1917	Cupin 2, conserved barrel domain protein
DYI28_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS11700	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DYI28_RS11705	COG3118	belongs to the thioredoxin family
DYI28_RS11710	COG0439	Biotin carboxylase
DYI28_RS11720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI28_RS11730	COG2873	o-acetylhomoserine
DYI28_RS11765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DYI28_RS11775	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DYI28_RS11780	COG1088	dTDP-glucose 4,6-dehydratase activity
DYI28_RS11785	COG1575	Belongs to the MenA family. Type 1 subfamily
DYI28_RS11790	COG1408	metallophosphoesterase
DYI28_RS11795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DYI28_RS11800	COG0194	GDP metabolic process
DYI28_RS11820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYI28_RS11825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYI28_RS11835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYI28_RS11840	COG0750	zinc metalloprotease
DYI28_RS11855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYI28_RS11865	COG2814	Major facilitator Superfamily
DYI28_RS11875	COG1328	CTP reductase activity
DYI28_RS11930	COG1629	transport
DYI28_RS11930	COG4206	TonB-dependent receptor
DYI28_RS11940	COG4206	TonB-dependent receptor
DYI28_RS11940	COG1629	transport
DYI28_RS11980	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS12000	COG1538	Outer membrane efflux protein
DYI28_RS12020	COG1629	transport
DYI28_RS12065	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS12080	COG0561	phosphatase activity
DYI28_RS12085	COG4771	TonB-dependent receptor
DYI28_RS12110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DYI28_RS12130	COG3550	peptidyl-serine autophosphorylation
DYI28_RS12155	COG1505	serine-type exopeptidase activity
DYI28_RS12170	COG3119	arylsulfatase activity
DYI28_RS12175	COG3119	arylsulfatase activity
DYI28_RS12185	COG0617	tRNA 3'-terminal CCA addition
DYI28_RS12200	COG0632	four-way junction helicase activity
DYI28_RS12205	COG0673	inositol 2-dehydrogenase activity
DYI28_RS12220	COG1272	protein, Hemolysin III
DYI28_RS12230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DYI28_RS12235	COG1629	transport
DYI28_RS12235	COG4206	TonB-dependent receptor
DYI28_RS12240	COG1629	transport
DYI28_RS12250	COG2204	response regulator
DYI28_RS12255	COG0488	(ABC) transporter
DYI28_RS12295	COG1595	DNA-templated transcription, initiation
DYI28_RS12305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYI28_RS12310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DYI28_RS12320	COG1522	sequence-specific DNA binding
DYI28_RS12350	COG0811	peptide transport
DYI28_RS12360	COG0084	hydrolase, TatD family'
DYI28_RS12380	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DYI28_RS12385	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DYI28_RS12390	COG0205	6-phosphofructokinase activity
DYI28_RS12430	COG0372	Belongs to the citrate synthase family
DYI28_RS12440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYI28_RS12445	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYI28_RS12455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYI28_RS12470	COG0028	Belongs to the TPP enzyme family
DYI28_RS12475	COG0129	dihydroxy-acid dehydratase activity
DYI28_RS12485	COG3681	Belongs to the UPF0597 family
DYI28_RS12505	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DYI28_RS12565	COG1629	transport
DYI28_RS12565	COG4206	TonB-dependent receptor
DYI28_RS12585	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI28_RS12585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI28_RS12590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DYI28_RS12595	COG0569	domain protein
DYI28_RS12595	COG2985	domain, Protein
DYI28_RS12615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DYI28_RS12625	COG0406	alpha-ribazole phosphatase activity
DYI28_RS12645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYI28_RS12695	COG3537	Alpha-1,2-mannosidase
DYI28_RS12715	COG0702	epimerase
DYI28_RS12720	COG4771	TonB-dependent receptor
DYI28_RS12725	COG1940	carbohydrate kinase activity
DYI28_RS12735	COG2188	Transcriptional regulator
DYI28_RS12760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYI28_RS12770	COG1609	Transcriptional regulator
DYI28_RS12770	COG2207	Transcriptional regulator
DYI28_RS12775	COG0534	Mate efflux family protein
DYI28_RS12780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DYI28_RS12785	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DYI28_RS12790	COG0166	Belongs to the GPI family
DYI28_RS12805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYI28_RS12825	COG2502	aspartate--ammonia ligase
DYI28_RS12830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DYI28_RS12845	COG3876	Protein conserved in bacteria
DYI28_RS12855	COG2315	Protein conserved in bacteria
DYI28_RS12875	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS12885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DYI28_RS12890	COG0778	Nitroreductase
DYI28_RS12900	COG1640	4-alpha-glucanotransferase
DYI28_RS12920	COG1216	Glycosyl transferase, family 2
DYI28_RS12930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYI28_RS12935	COG1022	Amp-dependent synthetase and ligase
DYI28_RS12970	COG0359	binds to the 23S rRNA
DYI28_RS12975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DYI28_RS12980	COG0360	Binds together with S18 to 16S ribosomal RNA
DYI28_RS13000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYI28_RS13005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYI28_RS13045	COG2431	L-lysine efflux transmembrane transporter activity
DYI28_RS13095	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYI28_RS13110	COG4206	TonB-dependent receptor
DYI28_RS13110	COG1629	transport
DYI28_RS13125	COG2234	aminopeptidase activity
DYI28_RS13140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYI28_RS13145	COG0802	atpase or kinase
DYI28_RS13170	COG0714	Associated with various cellular activities
DYI28_RS13205	COG3118	belongs to the thioredoxin family
DYI28_RS13215	COG0726	polysaccharide deacetylase
DYI28_RS13230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS13235	COG4771	TonB-dependent receptor
DYI28_RS13250	COG0457	Tetratricopeptide repeat
DYI28_RS13255	COG2814	Major facilitator Superfamily
DYI28_RS13270	COG0688	phosphatidylethanolamine metabolic process
DYI28_RS13275	COG1183	phosphatidylcholine synthase activity
DYI28_RS13295	COG0792	nuclease activity
DYI28_RS13310	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYI28_RS13320	COG0534	Mate efflux family protein
DYI28_RS13325	COG0528	UMP kinase activity
DYI28_RS13340	COG3250	beta-galactosidase activity
DYI28_RS13350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS13355	COG1629	transport
DYI28_RS13355	COG4206	TonB-dependent receptor
DYI28_RS13360	COG3292	Two component regulator propeller
DYI28_RS13360	COG2205	protein histidine kinase activity
DYI28_RS13360	COG0745	RESPONSE REGULATOR receiver
DYI28_RS13370	COG0233	cytoplasmic translational termination
DYI28_RS13375	COG1162	GTPase activity
DYI28_RS13390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYI28_RS13405	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DYI28_RS13405	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYI28_RS13420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYI28_RS13430	COG4206	TonB-dependent receptor
DYI28_RS13430	COG1629	transport
DYI28_RS13440	COG4771	TonB-dependent receptor
DYI28_RS13445	COG4974	Belongs to the 'phage' integrase family
DYI28_RS13450	COG4206	TonB-dependent receptor
DYI28_RS13450	COG1629	transport
DYI28_RS13465	COG2095	MarC family integral membrane protein
DYI28_RS13480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DYI28_RS13490	COG1435	thymidine kinase activity
DYI28_RS13495	COG0628	permease
DYI28_RS13520	COG3328	transposase activity
DYI28_RS13530	COG1396	sequence-specific DNA binding
DYI28_RS13540	COG4771	TonB-dependent receptor
DYI28_RS13600	COG2076	Multidrug Resistance protein
DYI28_RS13615	COG0475	glutathione-regulated potassium exporter activity
DYI28_RS13615	COG0589	response to stress
DYI28_RS13640	COG2207	Transcriptional regulator
DYI28_RS13650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYI28_RS13675	COG0534	Mate efflux family protein
DYI28_RS13695	COG1522	sequence-specific DNA binding
DYI28_RS13715	COG0668	transmembrane transport
DYI28_RS13735	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYI28_RS13740	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
DYI28_RS13745	COG0460	homoserine dehydrogenase
DYI28_RS13745	COG0527	aspartate kinase activity
DYI28_RS13755	COG0252	asparaginase activity
DYI28_RS13760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DYI28_RS13765	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DYI28_RS13775	COG4771	TonB-dependent receptor
DYI28_RS13780	COG5433	transposase activity
DYI28_RS13800	COG0826	peptidase U32
DYI28_RS13805	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DYI28_RS13820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DYI28_RS13840	COG0519	Catalyzes the synthesis of GMP from XMP
DYI28_RS13845	COG5002	protein histidine kinase activity
DYI28_RS13850	COG2205	protein histidine kinase activity
DYI28_RS13860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DYI28_RS13865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DYI28_RS13870	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DYI28_RS13890	COG3387	PFAM Glycoside hydrolase 15-related
DYI28_RS13925	COG5433	transposase activity
DYI28_RS13940	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS13975	COG4771	TonB-dependent receptor
DYI28_RS14015	COG0702	epimerase
DYI28_RS14020	COG4771	TonB-dependent receptor
DYI28_RS14045	COG0616	signal peptide processing
DYI28_RS14050	COG1663	tetraacyldisaccharide 4'-kinase activity
DYI28_RS14055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DYI28_RS14060	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DYI28_RS14080	COG0513	Belongs to the DEAD box helicase family
DYI28_RS14085	COG2070	2-Nitropropane dioxygenase
DYI28_RS14090	COG0724	RNA recognition motif
DYI28_RS14110	COG3973	AAA domain
DYI28_RS14120	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS14150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DYI28_RS14195	COG2885	chlorophyll binding
DYI28_RS14225	COG0784	Response regulator, receiver
DYI28_RS14225	COG2205	protein histidine kinase activity
DYI28_RS14225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYI28_RS14225	COG2198	Histidine kinase
DYI28_RS14255	COG0519	Catalyzes the synthesis of GMP from XMP
DYI28_RS14365	COG0358	DNA primase activity
DYI28_RS14475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYI28_RS14540	COG2204	response regulator
DYI28_RS14545	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYI28_RS14565	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS14570	COG0737	Belongs to the 5'-nucleotidase family
DYI28_RS14575	COG0737	Belongs to the 5'-nucleotidase family
DYI28_RS14580	COG0335	large ribosomal subunit rRNA binding
DYI28_RS14590	COG1136	(ABC) transporter
DYI28_RS14595	COG0577	efflux transmembrane transporter activity
DYI28_RS14595	COG1136	(ABC) transporter
DYI28_RS14600	COG0577	efflux transmembrane transporter activity
DYI28_RS14600	COG1136	(ABC) transporter
DYI28_RS14615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYI28_RS14615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYI28_RS14625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYI28_RS14645	COG2996	Protein conserved in bacteria
DYI28_RS14650	COG0039	L-malate dehydrogenase activity
DYI28_RS14665	COG2217	Heavy metal translocating P-type atpase
DYI28_RS14675	COG1595	DNA-templated transcription, initiation
DYI28_RS14685	COG1629	transport
DYI28_RS14715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYI28_RS14720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DYI28_RS14725	COG0509	glycine decarboxylation via glycine cleavage system
DYI28_RS14740	COG0006	proline dipeptidase activity
DYI28_RS14745	COG3458	cephalosporin-C deacetylase activity
DYI28_RS14760	COG1283	sodium-dependent phosphate transmembrane transporter activity
DYI28_RS14770	COG1773	rubredoxin
DYI28_RS14780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DYI28_RS14785	COG1011	Hydrolase
DYI28_RS14790	COG0196	riboflavin kinase activity
DYI28_RS14795	COG1266	CAAX protease self-immunity
DYI28_RS14800	COG2166	iron-sulfur cluster assembly
DYI28_RS14805	COG2234	aminopeptidase activity
DYI28_RS14810	COG1619	proteins homologs of microcin C7 resistance protein MccF
DYI28_RS14820	COG0280	phosphate acetyltransferase
DYI28_RS14825	COG3426	butyrate kinase activity
DYI28_RS14830	COG3537	Alpha-1,2-mannosidase
DYI28_RS14850	COG1185	polyribonucleotide nucleotidyltransferase activity
DYI28_RS14860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYI28_RS14880	COG0076	glutamate decarboxylase activity
DYI28_RS14885	COG2066	Belongs to the glutaminase family
DYI28_RS14895	COG0531	amino acid
DYI28_RS14915	COG3345	alpha-galactosidase
DYI28_RS14935	COG1131	(ABC) transporter
DYI28_RS15015	COG0667	Aldo Keto reductase
DYI28_RS15020	COG1696	Membrane protein involved in D-alanine export
DYI28_RS15055	COG1309	transcriptional regulator
DYI28_RS15060	COG2986	histidine ammonia-lyase
DYI28_RS15070	COG1228	amidohydrolase
DYI28_RS15080	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DYI28_RS15090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYI28_RS15105	COG0203	ribosomal protein L17
DYI28_RS15110	COG0202	RNA polymerase activity
DYI28_RS15115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DYI28_RS15120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DYI28_RS15125	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DYI28_RS15130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYI28_RS15135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DYI28_RS15150	COG0200	Binds to the 23S rRNA
DYI28_RS15155	COG1841	ribosomal large subunit assembly
DYI28_RS15160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DYI28_RS15165	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DYI28_RS15170	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DYI28_RS15175	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DYI28_RS15180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DYI28_RS15185	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DYI28_RS15190	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DYI28_RS15195	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DYI28_RS15200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DYI28_RS15205	COG0255	Belongs to the universal ribosomal protein uL29 family
DYI28_RS15210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DYI28_RS15215	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DYI28_RS15220	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYI28_RS15225	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DYI28_RS15230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYI28_RS15235	COG0089	rRNA binding
DYI28_RS15240	COG0088	Forms part of the polypeptide exit tunnel
DYI28_RS15245	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DYI28_RS15250	COG0051	transcription antitermination factor activity, RNA binding
DYI28_RS15255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYI28_RS15260	COG0049	tRNA binding
DYI28_RS15265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYI28_RS15275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DYI28_RS15280	COG0085	RNA polymerase activity
DYI28_RS15285	COG0222	ribosome binding
DYI28_RS15290	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DYI28_RS15295	COG0081	regulation of translation
DYI28_RS15300	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DYI28_RS15310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYI28_RS15320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYI28_RS15350	COG4974	Belongs to the 'phage' integrase family
DYI28_RS15355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DYI28_RS15365	COG0006	proline dipeptidase activity
DYI28_RS15370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DYI28_RS15380	COG3118	belongs to the thioredoxin family
DYI28_RS15395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYI28_RS15405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYI28_RS15415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYI28_RS15430	COG1595	DNA-templated transcription, initiation
DYI28_RS15470	COG3292	Two component regulator propeller
DYI28_RS15470	COG2205	protein histidine kinase activity
DYI28_RS15470	COG0745	RESPONSE REGULATOR receiver
DYI28_RS15475	COG1629	transport
DYI28_RS15480	COG0702	epimerase
DYI28_RS15530	COG0745	RESPONSE REGULATOR receiver
DYI28_RS15530	COG2205	protein histidine kinase activity
DYI28_RS15530	COG3292	Two component regulator propeller
DYI28_RS15530	COG0745	RESPONSE REGULATOR receiver
DYI28_RS15530	COG2205	protein histidine kinase activity
DYI28_RS15530	COG3292	Two component regulator propeller
DYI28_RS15665	COG3015	lipoprotein NlpE involved in copper resistance
DYI28_RS15715	COG0428	transporter
DYI28_RS15725	COG2375	cellular response to nickel ion
DYI28_RS15725	COG1132	(ABC) transporter
DYI28_RS15730	COG1132	(ABC) transporter
DYI28_RS15750	COG4771	TonB-dependent receptor
DYI28_RS15760	COG2801	Transposase and inactivated derivatives
DYI28_RS15780	COG0622	Phosphoesterase
DYI28_RS15925	COG1027	Aspartate ammonia-lyase
DYI28_RS15930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DYI28_RS15935	COG0252	asparaginase activity
DYI28_RS15950	COG2096	Adenosyltransferase
DYI28_RS15985	COG0501	Belongs to the peptidase M48B family
DYI28_RS16030	COG2972	Histidine kinase
DYI28_RS16045	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DYI28_RS16045	COG0662	Cupin 2, conserved barrel domain protein
DYI28_RS16050	COG0318	PFAM AMP-dependent synthetase and ligase
DYI28_RS16055	COG1396	sequence-specific DNA binding
DYI28_RS16065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DYI28_RS16085	COG2059	Chromate
DYI28_RS16100	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DYI28_RS16105	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DYI28_RS16150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DYI28_RS16160	COG0793	Belongs to the peptidase S41A family
DYI28_RS16165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYI28_RS16180	COG1040	competence protein
DYI28_RS16225	COG2610	gluconate transmembrane transporter activity
DYI28_RS16230	COG1929	Belongs to the glycerate kinase type-1 family
DYI28_RS16250	COG1629	transport
DYI28_RS16260	COG1609	Transcriptional regulator
DYI28_RS16265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYI28_RS16270	COG1629	transport
DYI28_RS16270	COG4206	TonB-dependent receptor
DYI28_RS16300	COG3693	PFAM glycoside hydrolase, family 10
DYI28_RS16300	COG2382	esterase
DYI28_RS16335	COG4771	TonB-dependent receptor
DYI28_RS16340	COG2205	protein histidine kinase activity
DYI28_RS16340	COG0745	RESPONSE REGULATOR receiver
DYI28_RS16340	COG3292	Two component regulator propeller
DYI28_RS16360	COG2816	NAD+ diphosphatase activity
DYI28_RS16405	COG0018	arginyl-trna synthetase
DYI28_RS16415	COG0705	Rhomboid family
DYI28_RS16430	COG0339	signal peptide processing
DYI28_RS16435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYI28_RS16445	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYI28_RS16445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYI28_RS16450	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYI28_RS16465	COG3250	beta-galactosidase activity
DYI28_RS16470	COG3458	cephalosporin-C deacetylase activity
DYI28_RS16475	COG3345	alpha-galactosidase
DYI28_RS16480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYI28_RS16485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS16525	COG4771	TonB-dependent receptor
DYI28_RS16545	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYI28_RS16550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYI28_RS16570	COG4974	Belongs to the 'phage' integrase family
DYI28_RS16585	COG0606	chelatase, subunit chli
DYI28_RS16590	COG2205	protein histidine kinase activity
DYI28_RS16615	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS16620	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS16635	COG1216	Glycosyl transferase, family 2
DYI28_RS16660	COG1216	Glycosyl transferase, family 2
DYI28_RS16670	COG1216	Glycosyl transferase, family 2
DYI28_RS16670	COG1442	glycosyl transferase family 8
DYI28_RS16725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI28_RS16730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYI28_RS16745	COG4974	Belongs to the 'phage' integrase family
DYI28_RS16750	COG4974	Belongs to the 'phage' integrase family
DYI28_RS16825	COG1629	transport
DYI28_RS16830	COG1192	Involved in chromosome partitioning
DYI28_RS16860	COG1120	ATPase activity
DYI28_RS16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYI28_RS16930	COG0702	epimerase
DYI28_RS16935	COG4771	TonB-dependent receptor
DYI28_RS16945	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS16950	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS16970	COG4771	TonB-dependent receptor
DYI28_RS16990	COG3292	Two component regulator propeller
DYI28_RS16990	COG2205	protein histidine kinase activity
DYI28_RS16990	COG0745	RESPONSE REGULATOR receiver
DYI28_RS17010	COG0673	inositol 2-dehydrogenase activity
DYI28_RS17020	COG0673	inositol 2-dehydrogenase activity
DYI28_RS17025	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS17030	COG2205	protein histidine kinase activity
DYI28_RS17030	COG3292	Two component regulator propeller
DYI28_RS17030	COG0745	RESPONSE REGULATOR receiver
DYI28_RS17045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI28_RS17045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYI28_RS17060	COG3475	LICD family
DYI28_RS17075	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS17105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYI28_RS17110	COG0545	Peptidyl-prolyl cis-trans isomerase
DYI28_RS17115	COG0545	Peptidyl-prolyl cis-trans isomerase
DYI28_RS17170	COG0732	type I restriction modification DNA specificity domain
DYI28_RS17175	COG4974	Belongs to the 'phage' integrase family
DYI28_RS17245	COG0561	phosphatase activity
DYI28_RS17310	COG4771	TonB-dependent receptor
DYI28_RS17315	COG0702	epimerase
DYI28_RS17325	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYI28_RS17330	COG3250	beta-galactosidase activity
DYI28_RS17335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYI28_RS17345	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DYI28_RS17350	COG2211	Major facilitator Superfamily
DYI28_RS17355	COG3408	Glycogen debranching enzyme
DYI28_RS17380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DYI28_RS17385	COG0793	Belongs to the peptidase S41A family
DYI28_RS17385	COG3409	Peptidoglycan-binding domain 1 protein
DYI28_RS17390	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS17395	COG3250	beta-galactosidase activity
DYI28_RS17400	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS17405	COG0745	RESPONSE REGULATOR receiver
DYI28_RS17405	COG2205	protein histidine kinase activity
DYI28_RS17405	COG3292	Two component regulator propeller
DYI28_RS17410	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYI28_RS17415	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS17435	COG4771	TonB-dependent receptor
DYI28_RS17440	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS17450	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DYI28_RS17570	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS17585	COG0702	epimerase
DYI28_RS17590	COG4771	TonB-dependent receptor
DYI28_RS17600	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DYI28_RS17635	COG1629	transport
DYI28_RS17655	COG0584	glycerophosphoryl diester phosphodiesterase
DYI28_RS17670	COG0612	Peptidase, M16
DYI28_RS17685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYI28_RS17715	COG3250	beta-galactosidase activity
DYI28_RS17730	COG3591	Belongs to the peptidase S1B family
DYI28_RS17750	COG2255	four-way junction helicase activity
DYI28_RS17755	COG0700	Nucleoside recognition
DYI28_RS17760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DYI28_RS17800	COG4771	TonB-dependent receptor
DYI28_RS17840	COG0445	tRNA wobble uridine modification
DYI28_RS17845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYI28_RS17850	COG0322	excinuclease ABC activity
DYI28_RS17855	COG1490	D-aminoacyl-tRNA deacylase activity
DYI28_RS17860	COG1694	Mazg nucleotide pyrophosphohydrolase
DYI28_RS17865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYI28_RS17880	COG0142	geranyltranstransferase activity
DYI28_RS17885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYI28_RS17885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYI28_RS17895	COG3279	Response regulator of the LytR AlgR family
DYI28_RS17905	COG1045	serine acetyltransferase
DYI28_RS17910	COG0116	Belongs to the methyltransferase superfamily
DYI28_RS17910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYI28_RS17920	COG0823	Involved in the tonB-independent uptake of proteins
DYI28_RS17920	COG1506	peptidase
DYI28_RS17935	COG1238	metal cluster binding
DYI28_RS17950	COG1121	(ABC) transporter
DYI28_RS17960	COG0726	polysaccharide deacetylase
DYI28_RS18010	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS18015	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DYI28_RS18025	COG1629	transport
DYI28_RS18025	COG4206	TonB-dependent receptor
DYI28_RS18035	COG2205	protein histidine kinase activity
DYI28_RS18035	COG0784	Response regulator, receiver
DYI28_RS18050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DYI28_RS18060	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DYI28_RS18065	COG0594	ribonuclease P activity
DYI28_RS18080	COG1611	Belongs to the LOG family
DYI28_RS18115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYI28_RS18125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYI28_RS18130	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYI28_RS18135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYI28_RS18140	COG1968	undecaprenyl-diphosphatase activity
DYI28_RS18150	COG2177	Part of the ABC transporter FtsEX involved in
DYI28_RS18175	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS18200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYI28_RS18210	COG0427	acetyl-CoA hydrolase
DYI28_RS18215	COG2027	D-alanyl-D-alanine carboxypeptidase
DYI28_RS18245	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DYI28_RS18260	COG4771	TonB-dependent receptor
DYI28_RS18275	COG3292	Two component regulator propeller
DYI28_RS18275	COG2205	protein histidine kinase activity
DYI28_RS18275	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18280	COG1592	Rubrerythrin
DYI28_RS18285	COG0659	secondary active sulfate transmembrane transporter activity
DYI28_RS18290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS18305	COG1629	transport
DYI28_RS18305	COG4206	TonB-dependent receptor
DYI28_RS18335	COG3292	Two component regulator propeller
DYI28_RS18335	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18335	COG2205	protein histidine kinase activity
DYI28_RS18335	COG2205	protein histidine kinase activity
DYI28_RS18335	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18335	COG3292	Two component regulator propeller
DYI28_RS18360	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18360	COG2205	protein histidine kinase activity
DYI28_RS18360	COG3292	Two component regulator propeller
DYI28_RS18365	COG1629	transport
DYI28_RS18385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS18400	COG1629	transport
DYI28_RS18405	COG0702	epimerase
DYI28_RS18430	COG0731	radical SAM domain protein
DYI28_RS18430	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYI28_RS18455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DYI28_RS18460	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS18470	COG3250	beta-galactosidase activity
DYI28_RS18485	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS18490	COG1629	transport
DYI28_RS18490	COG4206	TonB-dependent receptor
DYI28_RS18500	COG1360	Flagellar Motor Protein
DYI28_RS18505	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYI28_RS18510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DYI28_RS18515	COG0495	leucyl-tRNA aminoacylation
DYI28_RS18525	COG3250	beta-galactosidase activity
DYI28_RS18540	COG0697	spore germination
DYI28_RS18545	COG1785	Belongs to the alkaline phosphatase family
DYI28_RS18555	COG3537	Alpha-1,2-mannosidase
DYI28_RS18565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYI28_RS18570	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DYI28_RS18575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYI28_RS18580	COG0012	GTP binding
DYI28_RS18600	COG1629	transport
DYI28_RS18600	COG4206	TonB-dependent receptor
DYI28_RS18615	COG2814	Major facilitator Superfamily
DYI28_RS18630	COG3119	arylsulfatase activity
DYI28_RS18655	COG1629	transport
DYI28_RS18655	COG4206	TonB-dependent receptor
DYI28_RS18665	COG1629	transport
DYI28_RS18665	COG4206	TonB-dependent receptor
DYI28_RS18685	COG3292	Two component regulator propeller
DYI28_RS18685	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18685	COG2205	protein histidine kinase activity
DYI28_RS18695	COG3119	arylsulfatase activity
DYI28_RS18695	COG3408	Glycogen debranching enzyme
DYI28_RS18740	COG4771	TonB-dependent receptor
DYI28_RS18745	COG0702	epimerase
DYI28_RS18765	COG3292	Two component regulator propeller
DYI28_RS18765	COG0745	RESPONSE REGULATOR receiver
DYI28_RS18765	COG2205	protein histidine kinase activity
DYI28_RS18770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS18780	COG4771	TonB-dependent receptor
DYI28_RS18785	COG0702	epimerase
DYI28_RS18790	COG3254	rhamnose metabolic process
DYI28_RS18835	COG1917	Cupin 2, conserved barrel domain protein
DYI28_RS18840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYI28_RS18845	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS18860	COG1629	transport
DYI28_RS18860	COG4206	TonB-dependent receptor
DYI28_RS18870	COG5002	protein histidine kinase activity
DYI28_RS18880	COG4206	TonB-dependent receptor
DYI28_RS18880	COG1629	transport
DYI28_RS18885	COG0702	epimerase
DYI28_RS18905	COG1373	ATPase (AAA superfamily
DYI28_RS18925	COG0557	exoribonuclease II activity
DYI28_RS18985	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYI28_RS18990	COG0826	peptidase U32
DYI28_RS19000	COG0758	DNA mediated transformation
DYI28_RS19020	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DYI28_RS19170	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYI28_RS19175	COG1053	succinate dehydrogenase
DYI28_RS19200	COG2205	protein histidine kinase activity
DYI28_RS19200	COG3292	Two component regulator propeller
DYI28_RS19200	COG0745	RESPONSE REGULATOR receiver
DYI28_RS19210	COG4206	TonB-dependent receptor
DYI28_RS19210	COG1629	transport
DYI28_RS19215	COG0702	epimerase
DYI28_RS19235	COG0745	RESPONSE REGULATOR receiver
DYI28_RS19235	COG2205	protein histidine kinase activity
DYI28_RS19235	COG3292	Two component regulator propeller
DYI28_RS19240	COG4771	TonB-dependent receptor
DYI28_RS19245	COG0702	epimerase
DYI28_RS19375	COG1120	ATPase activity
DYI28_RS19380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYI28_RS19410	COG4886	Leucine-rich repeat (LRR) protein
DYI28_RS19410	COG4932	domain protein
DYI28_RS19460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYI28_RS19520	COG0741	lytic transglycosylase activity
DYI28_RS19520	COG1196	nuclear chromosome segregation
DYI28_RS19520	COG0739	heme binding
DYI28_RS19555	COG1192	Involved in chromosome partitioning
DYI28_RS19570	COG1475	DNA binding
DYI28_RS19655	COG4974	Belongs to the 'phage' integrase family
DYI28_RS19660	COG4974	Belongs to the 'phage' integrase family
DYI28_RS19715	COG0300	oxidoreductase activity
DYI28_RS19715	COG3321	synthase
DYI28_RS19715	COG0318	PFAM AMP-dependent synthetase and ligase
DYI28_RS19715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYI28_RS19715	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS19770	COG0582	viral genome integration into host DNA
DYI28_RS19795	COG2226	methyltransferase
DYI28_RS19810	COG1132	(ABC) transporter
DYI28_RS19810	COG2375	cellular response to nickel ion
DYI28_RS19815	COG1132	(ABC) transporter
DYI28_RS19875	COG0681	Belongs to the peptidase S26 family
DYI28_RS19885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DYI28_RS19915	COG1215	transferase activity, transferring glycosyl groups
DYI28_RS19935	COG5492	domain, Protein
DYI28_RS19960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYI28_RS19970	COG0702	epimerase
DYI28_RS19975	COG4771	TonB-dependent receptor
DYI28_RS19980	COG3119	arylsulfatase activity
DYI28_RS19985	COG0745	RESPONSE REGULATOR receiver
DYI28_RS19985	COG3292	Two component regulator propeller
DYI28_RS19985	COG0745	RESPONSE REGULATOR receiver
DYI28_RS19985	COG2205	protein histidine kinase activity
DYI28_RS19985	COG2205	protein histidine kinase activity
DYI28_RS19985	COG3292	Two component regulator propeller
DYI28_RS20000	COG0702	epimerase
DYI28_RS20005	COG1629	transport
DYI28_RS20015	COG4771	TonB-dependent receptor
DYI28_RS20035	COG0738	Major facilitator superfamily
DYI28_RS20050	COG1940	carbohydrate kinase activity
DYI28_RS20055	COG3250	beta-galactosidase activity
DYI28_RS20065	COG1609	Transcriptional regulator
DYI28_RS20075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYI28_RS20080	COG1538	Outer membrane efflux protein
DYI28_RS20095	COG3250	beta-galactosidase activity
DYI28_RS20100	COG4771	TonB-dependent receptor
DYI28_RS20115	COG0702	epimerase
DYI28_RS20150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS20155	COG3119	arylsulfatase activity
DYI28_RS20160	COG5492	domain, Protein
DYI28_RS20165	COG0215	cysteine-tRNA ligase activity
DYI28_RS20170	COG0561	phosphatase activity
DYI28_RS20195	COG0482	sulfurtransferase activity
DYI28_RS20205	COG0205	6-phosphofructokinase activity
DYI28_RS20210	COG0571	ribonuclease III activity
DYI28_RS20215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYI28_RS20220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYI28_RS20225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYI28_RS20230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYI28_RS20265	COG0438	transferase activity, transferring glycosyl groups
DYI28_RS20270	COG3475	LICD family
DYI28_RS20275	COG4750	Nucleotidyl transferase
DYI28_RS20280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYI28_RS20290	COG1442	glycosyl transferase family 8
DYI28_RS20290	COG1216	Glycosyl transferase, family 2
DYI28_RS20310	COG1216	Glycosyl transferase, family 2
DYI28_RS20315	COG1442	glycosyl transferase family 8
DYI28_RS20315	COG1216	Glycosyl transferase, family 2
DYI28_RS20360	COG1132	(ABC) transporter
DYI28_RS20370	COG0463	Glycosyl transferase, family 2
DYI28_RS20380	COG1368	sulfuric ester hydrolase activity
DYI28_RS20390	COG3341	Caulimovirus viroplasmin
DYI28_RS20390	COG0328	RNA-DNA hybrid ribonuclease activity
DYI28_RS20400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYI28_RS20410	COG0326	Molecular chaperone. Has ATPase activity
DYI28_RS20420	COG1166	arginine decarboxylase activity
DYI28_RS20425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYI28_RS20430	COG1595	DNA-templated transcription, initiation
DYI28_RS20455	COG0779	Required for maturation of 30S ribosomal subunits
DYI28_RS20460	COG0195	Participates in both transcription termination and antitermination
DYI28_RS20465	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYI28_RS20475	COG0719	Fe-S assembly protein
DYI28_RS20480	COG0396	ATPase activity
DYI28_RS20485	COG0719	Fe-S assembly protein
DYI28_RS20490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYI28_RS20505	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20505	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20505	COG3292	Two component regulator propeller
DYI28_RS20505	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20505	COG2205	protein histidine kinase activity
DYI28_RS20505	COG3292	Two component regulator propeller
DYI28_RS20505	COG2205	protein histidine kinase activity
DYI28_RS20505	COG3292	Two component regulator propeller
DYI28_RS20505	COG2205	protein histidine kinase activity
DYI28_RS20510	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DYI28_RS20515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYI28_RS20535	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DYI28_RS20555	COG0187	DNA topoisomerase II activity
DYI28_RS20560	COG0268	Binds directly to 16S ribosomal RNA
DYI28_RS20610	COG1381	Involved in DNA repair and RecF pathway recombination
DYI28_RS20665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DYI28_RS20680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYI28_RS20685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYI28_RS20690	COG0772	Belongs to the SEDS family
DYI28_RS20695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DYI28_RS20700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYI28_RS20705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DYI28_RS20720	COG0275	rRNA processing
DYI28_RS20725	COG2001	Belongs to the MraZ family
DYI28_RS20745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DYI28_RS20750	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20750	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20750	COG2205	protein histidine kinase activity
DYI28_RS20750	COG3292	Two component regulator propeller
DYI28_RS20750	COG3292	Two component regulator propeller
DYI28_RS20750	COG2205	protein histidine kinase activity
DYI28_RS20755	COG3940	Belongs to the glycosyl hydrolase 43 family
DYI28_RS20765	COG4771	TonB-dependent receptor
DYI28_RS20795	COG0756	dUTP diphosphatase activity
DYI28_RS20810	COG4942	peptidase
DYI28_RS20815	COG0745	RESPONSE REGULATOR receiver
DYI28_RS20815	COG2205	protein histidine kinase activity
DYI28_RS20815	COG3292	Two component regulator propeller
DYI28_RS20825	COG3119	arylsulfatase activity
DYI28_RS20840	COG4771	TonB-dependent receptor
DYI28_RS20850	COG4206	TonB-dependent receptor
DYI28_RS20850	COG1629	transport
DYI28_RS20870	COG0702	epimerase
DYI28_RS20875	COG1629	transport
DYI28_RS20905	COG4771	TonB-dependent receptor
DYI28_RS20910	COG0702	epimerase
DYI28_RS20920	COG3119	arylsulfatase activity
DYI28_RS20940	COG3119	arylsulfatase activity
DYI28_RS20950	COG3119	arylsulfatase activity
DYI28_RS20960	COG3119	arylsulfatase activity
DYI28_RS20990	COG4771	TonB-dependent receptor
DYI28_RS20995	COG0561	phosphatase activity
DYI28_RS21035	COG2017	converts alpha-aldose to the beta-anomer
DYI28_RS21160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI28_RS21165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DYI28_RS21170	COG1022	Amp-dependent synthetase and ligase
DYI28_RS21175	COG0612	Peptidase, M16
DYI28_RS21180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DYI28_RS21190	COG2954	triphosphatase activity
DYI28_RS21200	COG1373	ATPase (AAA superfamily
DYI28_RS21460	COG3392	D12 class N6 adenine-specific DNA methyltransferase
DYI28_RS21500	COG0561	phosphatase activity
DYI28_RS21505	COG4771	TonB-dependent receptor
DYI28_RS21535	COG0673	inositol 2-dehydrogenase activity
DYI28_RS21545	COG0673	inositol 2-dehydrogenase activity
DYI28_RS21570	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DYI28_RS21580	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS21600	COG1629	transport
DYI28_RS21610	COG1609	Transcriptional regulator
DYI28_RS21610	COG2207	Transcriptional regulator
DYI28_RS21620	COG1373	ATPase (AAA superfamily
DYI28_RS21625	COG0423	glycine-tRNA ligase activity
DYI28_RS21635	COG1609	Transcriptional regulator
DYI28_RS21650	COG0738	Major facilitator superfamily
DYI28_RS21655	COG1063	alcohol dehydrogenase
DYI28_RS21665	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS21670	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS21675	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS21690	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS21695	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS21700	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS21705	COG4771	TonB-dependent receptor
DYI28_RS21720	COG0702	epimerase
DYI28_RS21745	COG2382	esterase
DYI28_RS21750	COG3507	Belongs to the glycosyl hydrolase 43 family
DYI28_RS21755	COG2205	protein histidine kinase activity
DYI28_RS21755	COG3292	Two component regulator propeller
DYI28_RS21755	COG0745	RESPONSE REGULATOR receiver
DYI28_RS21770	COG3292	Two component regulator propeller
DYI28_RS21770	COG0745	RESPONSE REGULATOR receiver
DYI28_RS21770	COG2205	protein histidine kinase activity
DYI28_RS21770	COG3292	Two component regulator propeller
DYI28_RS21770	COG0745	RESPONSE REGULATOR receiver
DYI28_RS21770	COG2205	protein histidine kinase activity
DYI28_RS21780	COG4771	TonB-dependent receptor
DYI28_RS21785	COG0561	phosphatase activity
DYI28_RS21815	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DYI28_RS21830	COG2211	Major facilitator Superfamily
DYI28_RS21840	COG1215	transferase activity, transferring glycosyl groups
DYI28_RS21845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYI28_RS21900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DYI28_RS21905	COG0589	response to stress
DYI28_RS21905	COG0475	glutathione-regulated potassium exporter activity
DYI28_RS21910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYI28_RS21915	COG1136	(ABC) transporter
DYI28_RS21925	COG0733	neurotransmitter:sodium symporter activity
DYI28_RS21935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYI28_RS21940	COG0784	Response regulator, receiver
DYI28_RS21940	COG5002	protein histidine kinase activity
DYI28_RS21945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYI28_RS21950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DYI28_RS21970	COG1082	Xylose isomerase domain protein TIM barrel
DYI28_RS22000	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS22005	COG3292	Two component regulator propeller
DYI28_RS22005	COG2205	protein histidine kinase activity
DYI28_RS22005	COG0745	RESPONSE REGULATOR receiver
DYI28_RS22045	COG1346	cytolysis
DYI28_RS22050	COG1380	Effector of murein hydrolase LrgA
DYI28_RS22055	COG0280	phosphate acetyltransferase
DYI28_RS22060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DYI28_RS22075	COG2003	Belongs to the UPF0758 family
DYI28_RS22080	COG3292	Two component regulator propeller
DYI28_RS22080	COG2205	protein histidine kinase activity
DYI28_RS22080	COG0745	RESPONSE REGULATOR receiver
DYI28_RS22115	COG3250	beta-galactosidase activity
DYI28_RS22130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DYI28_RS22145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS22150	COG4206	TonB-dependent receptor
DYI28_RS22150	COG1629	transport
DYI28_RS22155	COG1082	Xylose isomerase domain protein TIM barrel
DYI28_RS22160	COG0366	Alpha amylase catalytic
DYI28_RS22170	COG1785	Belongs to the alkaline phosphatase family
DYI28_RS22175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYI28_RS22180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DYI28_RS22185	COG2815	serine threonine protein kinase
DYI28_RS22185	COG0515	serine threonine protein kinase
DYI28_RS22190	COG0564	pseudouridine synthase activity
DYI28_RS22215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYI28_RS22220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DYI28_RS22235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DYI28_RS22240	COG0436	Aminotransferase
DYI28_RS22540	COG4974	Belongs to the 'phage' integrase family
DYI28_RS22555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS22555	COG0551	DNA topoisomerase type I activity
DYI28_RS22570	COG4804	nuclease activity
DYI28_RS22600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYI28_RS22615	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYI28_RS22620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYI28_RS22630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYI28_RS22630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYI28_RS22635	COG2890	protein-(glutamine-N5) methyltransferase activity
DYI28_RS22645	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DYI28_RS22655	COG0165	Argininosuccinate lyase
DYI28_RS22715	COG0582	viral genome integration into host DNA
DYI28_RS22795	COG4206	TonB-dependent receptor
DYI28_RS22795	COG1629	transport
DYI28_RS22825	COG3292	Two component regulator propeller
DYI28_RS22825	COG2205	protein histidine kinase activity
DYI28_RS22825	COG0745	RESPONSE REGULATOR receiver
DYI28_RS22835	COG1595	DNA-templated transcription, initiation
DYI28_RS22840	COG1629	transport
DYI28_RS22860	COG3458	cephalosporin-C deacetylase activity
DYI28_RS22870	COG5433	transposase activity
DYI28_RS22905	COG1629	transport
DYI28_RS22920	COG4677	pectinesterase activity
DYI28_RS22925	COG2205	protein histidine kinase activity
DYI28_RS22925	COG0745	RESPONSE REGULATOR receiver
DYI28_RS22925	COG3292	Two component regulator propeller
DYI28_RS22935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYI28_RS22940	COG1917	Cupin 2, conserved barrel domain protein
DYI28_RS22940	COG1396	sequence-specific DNA binding
DYI28_RS22950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYI28_RS22955	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DYI28_RS22960	COG0137	argininosuccinate synthase activity
DYI28_RS22970	COG1438	arginine binding
DYI28_RS22980	COG1070	Carbohydrate kinase
DYI28_RS22985	COG4806	L-rhamnose isomerase
DYI28_RS22995	COG0235	Class ii aldolase
DYI28_RS23000	COG1454	alcohol dehydrogenase
DYI28_RS23010	COG3292	Two component regulator propeller
DYI28_RS23010	COG2205	protein histidine kinase activity
DYI28_RS23010	COG0745	RESPONSE REGULATOR receiver
DYI28_RS23015	COG4771	TonB-dependent receptor
DYI28_RS23020	COG0702	epimerase
DYI28_RS23050	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS23055	COG3250	beta-galactosidase activity
DYI28_RS23080	COG0564	pseudouridine synthase activity
DYI28_RS23110	COG3537	Alpha-1,2-mannosidase
DYI28_RS23120	COG0745	RESPONSE REGULATOR receiver
DYI28_RS23120	COG2205	protein histidine kinase activity
DYI28_RS23120	COG3292	Two component regulator propeller
DYI28_RS23140	COG4771	TonB-dependent receptor
DYI28_RS23160	COG3119	arylsulfatase activity
DYI28_RS23165	COG2204	response regulator
DYI28_RS23170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYI28_RS23170	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYI28_RS23175	COG0612	Peptidase, M16
DYI28_RS23180	COG0534	Mate efflux family protein
DYI28_RS23185	COG2205	protein histidine kinase activity
DYI28_RS23185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYI28_RS23200	COG4771	TonB-dependent receptor
DYI28_RS23215	COG0612	Peptidase, M16
DYI28_RS23245	COG0488	(ABC) transporter
DYI28_RS23250	COG3590	peptidase
DYI28_RS23255	COG0138	bifunctional purine biosynthesis protein purh
DYI28_RS23280	COG0772	Belongs to the SEDS family
DYI28_RS23290	COG1774	PSP1 C-terminal conserved region
DYI28_RS23295	COG0470	DNA polymerase III
DYI28_RS23300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYI28_RS23305	COG2193	ferroxidase activity
DYI28_RS23355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DYI28_RS23360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYI28_RS23365	COG1160	GTP binding
DYI28_RS23375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYI28_RS23380	COG1127	ABC transporter
DYI28_RS23385	COG0724	RNA recognition motif
DYI28_RS23390	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYI28_RS23395	COG0740	serine-type endopeptidase activity
DYI28_RS23400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYI28_RS23405	COG0514	ATP-dependent DNA helicase (RecQ)
DYI28_RS23410	COG0517	IMP dehydrogenase activity
DYI28_RS23410	COG0516	GMP reductase activity
DYI28_RS23425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYI28_RS23440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYI28_RS23520	COG3022	response to hydroperoxide
DYI28_RS23525	COG0110	maltose O-acetyltransferase activity
DYI28_RS23545	COG1187	pseudouridine synthase activity
DYI28_RS23550	COG0017	Asparaginyl-tRNA synthetase
DYI28_RS23560	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS23565	COG0745	RESPONSE REGULATOR receiver
DYI28_RS23565	COG3292	Two component regulator propeller
DYI28_RS23565	COG2205	protein histidine kinase activity
DYI28_RS23600	COG4771	TonB-dependent receptor
DYI28_RS23605	COG0702	epimerase
DYI28_RS23610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DYI28_RS23615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DYI28_RS23620	COG0052	Belongs to the universal ribosomal protein uS2 family
DYI28_RS23625	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYI28_RS23630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI28_RS23640	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DYI28_RS23645	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYI28_RS23650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DYI28_RS23665	COG0482	sulfurtransferase activity
DYI28_RS23675	COG1570	exodeoxyribonuclease VII activity
DYI28_RS23685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYI28_RS23695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYI28_RS23700	COG0489	protein tyrosine kinase activity
DYI28_RS23705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI28_RS23745	COG0039	L-malate dehydrogenase activity
DYI28_RS23760	COG4771	TonB-dependent receptor
DYI28_RS23795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYI28_RS23800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DYI28_RS23805	COG0811	peptide transport
DYI28_RS23810	COG0848	biopolymer transport protein
DYI28_RS23825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DYI28_RS23830	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DYI28_RS23835	COG0105	UTP biosynthetic process
DYI28_RS23840	COG0739	heme binding
DYI28_RS23855	COG0149	triose-phosphate isomerase activity
DYI28_RS23865	COG0302	gtp cyclohydrolase
DYI28_RS23870	COG0358	DNA primase activity
DYI28_RS23880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYI28_RS23900	COG0514	ATP-dependent DNA helicase (RecQ)
DYI28_RS23905	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DYI28_RS23905	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYI28_RS23960	COG1215	transferase activity, transferring glycosyl groups
DYI28_RS23965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYI28_RS23980	COG0726	polysaccharide deacetylase
DYI28_RS23995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYI28_RS24000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYI28_RS24025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYI28_RS24030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYI28_RS24035	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS24055	COG4771	TonB-dependent receptor
DYI28_RS24065	COG0009	L-threonylcarbamoyladenylate synthase
DYI28_RS24075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYI28_RS24080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYI28_RS24085	COG0658	competence protein
DYI28_RS24085	COG2333	competence protein COMEC
DYI28_RS24090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DYI28_RS24100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYI28_RS24125	COG4771	TonB-dependent receptor
DYI28_RS24145	COG1501	Belongs to the glycosyl hydrolase 31 family
DYI28_RS24150	COG3537	Alpha-1,2-mannosidase
DYI28_RS24165	COG3537	Alpha-1,2-mannosidase
DYI28_RS24170	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS24175	COG3279	Response regulator of the LytR AlgR family
DYI28_RS24180	COG3275	phosphorelay sensor kinase activity
DYI28_RS24195	COG0386	Belongs to the glutathione peroxidase family
DYI28_RS24205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYI28_RS24265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYI28_RS24275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYI28_RS24290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYI28_RS24295	COG0742	ribosomal rna small subunit methyltransferase
DYI28_RS24310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYI28_RS24340	COG1629	transport
DYI28_RS24340	COG4206	TonB-dependent receptor
DYI28_RS24370	COG3537	Alpha-1,2-mannosidase
DYI28_RS24375	COG3537	Alpha-1,2-mannosidase
DYI28_RS24395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DYI28_RS24400	COG0739	heme binding
DYI28_RS24410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYI28_RS24415	COG0741	lytic transglycosylase activity
DYI28_RS24415	COG1388	LysM domain
DYI28_RS24425	COG1475	DNA binding
DYI28_RS24430	COG1192	Involved in chromosome partitioning
DYI28_RS24435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYI28_RS24440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYI28_RS24455	COG0575	Belongs to the CDS family
DYI28_RS24460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYI28_RS24475	COG1196	nuclear chromosome segregation
DYI28_RS24480	COG2239	Acts as a magnesium transporter
DYI28_RS24485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYI28_RS24495	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYI28_RS24575	COG0668	transmembrane transport
DYI28_RS24580	COG0662	Cupin 2, conserved barrel domain protein
DYI28_RS24580	COG2207	Transcriptional regulator
DYI28_RS24595	COG5002	protein histidine kinase activity
DYI28_RS24595	COG0784	Response regulator, receiver
DYI28_RS24595	COG2198	Histidine kinase
DYI28_RS24605	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI28_RS24610	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYI28_RS24615	COG0713	ATP synthesis coupled electron transport
DYI28_RS24630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DYI28_RS24635	COG0649	NAD binding
DYI28_RS24635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI28_RS24640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI28_RS24645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYI28_RS24680	COG3250	beta-galactosidase activity
DYI28_RS24690	COG3250	beta-galactosidase activity
DYI28_RS24715	COG4771	TonB-dependent receptor
DYI28_RS24720	COG0702	epimerase
DYI28_RS24725	COG1629	transport
DYI28_RS24725	COG4206	TonB-dependent receptor
DYI28_RS24745	COG3537	Alpha-1,2-mannosidase
DYI28_RS24760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYI28_RS24765	COG0569	domain protein
DYI28_RS24770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYI28_RS24780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYI28_RS24785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DYI28_RS24790	COG0805	protein transport
DYI28_RS24800	COG2271	Major facilitator Superfamily
DYI28_RS24805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DYI28_RS24810	COG3775	system Galactitol-specific IIC component
DYI28_RS24815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS24825	COG2755	lipolytic protein G-D-S-L family
DYI28_RS24830	COG0745	RESPONSE REGULATOR receiver
DYI28_RS24830	COG2205	protein histidine kinase activity
DYI28_RS24830	COG3292	Two component regulator propeller
DYI28_RS24865	COG0702	epimerase
DYI28_RS24870	COG1629	transport
DYI28_RS24870	COG4206	TonB-dependent receptor
DYI28_RS24880	COG3279	Response regulator of the LytR AlgR family
DYI28_RS24905	COG4771	TonB-dependent receptor
DYI28_RS24910	COG0702	epimerase
DYI28_RS24925	COG4677	pectinesterase activity
DYI28_RS24935	COG5433	transposase activity
DYI28_RS24945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYI28_RS24950	COG0745	RESPONSE REGULATOR receiver
DYI28_RS24950	COG3292	Two component regulator propeller
DYI28_RS24950	COG2205	protein histidine kinase activity
DYI28_RS24955	COG1242	4 iron, 4 sulfur cluster binding
DYI28_RS24965	COG0363	glucosamine-6-phosphate deaminase activity
DYI28_RS24970	COG2755	lipolytic protein G-D-S-L family
DYI28_RS24970	COG0657	acetylesterase activity
DYI28_RS24975	COG0009	L-threonylcarbamoyladenylate synthase
DYI28_RS24985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYI28_RS24990	COG0561	phosphatase activity
DYI28_RS25000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYI28_RS25025	COG2755	lipolytic protein G-D-S-L family
DYI28_RS25060	COG0702	epimerase
DYI28_RS25065	COG4771	TonB-dependent receptor
DYI28_RS25085	COG4771	TonB-dependent receptor
DYI28_RS25105	COG3401	FG-GAP repeat protein
DYI28_RS25120	COG2755	lipolytic protein G-D-S-L family
DYI28_RS25130	COG3401	FG-GAP repeat protein
DYI28_RS25140	COG3254	rhamnose metabolic process
DYI28_RS25145	COG0745	RESPONSE REGULATOR receiver
DYI28_RS25145	COG2205	protein histidine kinase activity
DYI28_RS25145	COG2205	protein histidine kinase activity
DYI28_RS25145	COG0745	RESPONSE REGULATOR receiver
DYI28_RS25145	COG3292	Two component regulator propeller
DYI28_RS25145	COG3292	Two component regulator propeller
DYI28_RS25150	COG0657	acetylesterase activity
DYI28_RS25150	COG2755	lipolytic protein G-D-S-L family
DYI28_RS25165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS25180	COG4771	TonB-dependent receptor
DYI28_RS25185	COG0702	epimerase
DYI28_RS25200	COG4771	TonB-dependent receptor
DYI28_RS25280	COG2205	protein histidine kinase activity
DYI28_RS25280	COG3292	Two component regulator propeller
DYI28_RS25280	COG0745	RESPONSE REGULATOR receiver
DYI28_RS25280	COG3292	Two component regulator propeller
DYI28_RS25280	COG2205	protein histidine kinase activity
DYI28_RS25280	COG0745	RESPONSE REGULATOR receiver
DYI28_RS25300	COG0546	phosphoglycolate phosphatase activity
DYI28_RS25330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DYI28_RS25340	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DYI28_RS25350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYI28_RS25370	COG1629	transport
DYI28_RS25375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYI28_RS25390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DYI28_RS25390	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DYI28_RS25395	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYI28_RS25400	COG1078	dGTPase activity
DYI28_RS25405	COG0284	orotidine-5'-phosphate decarboxylase activity
DYI28_RS25410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DYI28_RS25415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DYI28_RS25420	COG1704	LemA family
DYI28_RS25435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYI28_RS25445	COG2226	methyltransferase
DYI28_RS25450	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DYI28_RS25455	COG1702	phosphate starvation-inducible protein PhoH
DYI28_RS25475	COG2268	Band 7 protein
DYI28_RS25485	COG0101	tRNA pseudouridine synthase activity
DYI28_RS25505	COG3250	beta-galactosidase activity
DYI28_RS25510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DYI28_RS25515	COG0673	inositol 2-dehydrogenase activity
DYI28_RS25520	COG0673	inositol 2-dehydrogenase activity
DYI28_RS25535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DYI28_RS25545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DYI28_RS25560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DYI28_RS25565	COG0793	Belongs to the peptidase S41A family
DYI28_RS25570	COG2131	deaminase
DYI28_RS25580	COG0339	signal peptide processing
DYI28_RS25585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DYI28_RS25590	COG1970	mechanosensitive ion channel activity
DYI28_RS25595	COG0519	Catalyzes the synthesis of GMP from XMP
DYI28_RS25595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYI28_RS25620	COG0297	glycogen (starch) synthase activity
DYI28_RS25640	COG0297	glycogen (starch) synthase activity
DYI28_RS25645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYI28_RS25650	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYI28_RS25655	COG0543	2 iron, 2 sulfur cluster binding
DYI28_RS25660	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYI28_RS25665	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DYI28_RS25670	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DYI28_RS25685	COG0791	NLP P60 protein
DYI28_RS25700	COG0612	Peptidase, M16
DYI28_RS25705	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DYI28_RS25710	COG1597	lipid kinase activity
DYI28_RS25715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYI28_RS25730	COG1136	(ABC) transporter
DYI28_RS25750	COG2211	Major facilitator Superfamily
DYI28_RS25765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYI28_RS25780	COG1674	ftsk spoiiie
DYI28_RS25790	COG0492	ferredoxin-NADP+ reductase activity
DYI28_RS25795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS25835	COG4206	TonB-dependent receptor
DYI28_RS25835	COG1629	transport
DYI28_RS25875	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYI28_RS25875	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYI28_RS25885	COG1234	tRNA 3'-trailer cleavage
DYI28_RS25890	COG2989	Protein conserved in bacteria
DYI28_RS25910	COG3956	TIGRFAM MazG family protein
DYI28_RS25930	COG0525	valine-tRNA ligase activity
DYI28_RS25935	COG0784	Response regulator, receiver
DYI28_RS25935	COG2205	protein histidine kinase activity
DYI28_RS25940	COG1595	DNA-templated transcription, initiation
DYI28_RS25950	COG4206	TonB-dependent receptor
DYI28_RS25950	COG1629	transport
DYI28_RS25955	COG0702	epimerase
DYI28_RS25970	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DYI28_RS25985	COG1595	DNA-templated transcription, initiation
DYI28_RS25995	COG1629	transport
DYI28_RS25995	COG4206	TonB-dependent receptor
DYI28_RS26000	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS26025	COG0653	protein targeting
DYI28_RS26030	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
DYI28_RS26040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DYI28_RS26060	COG1253	flavin adenine dinucleotide binding
DYI28_RS26065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYI28_RS26075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DYI28_RS26085	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DYI28_RS26090	COG2204	response regulator
DYI28_RS26130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYI28_RS26130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYI28_RS26150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DYI28_RS26155	COG0563	adenylate kinase activity
DYI28_RS26160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYI28_RS26165	COG1496	oxidoreductase activity
DYI28_RS26175	COG0739	heme binding
DYI28_RS26180	COG2706	6-phosphogluconolactonase activity
DYI28_RS26270	COG3142	Participates in the control of copper homeostasis
DYI28_RS26275	COG1418	mRNA catabolic process
DYI28_RS26315	COG4771	TonB-dependent receptor
DYI28_RS26320	COG0702	epimerase
DYI28_RS26350	COG0246	Mannitol dehydrogenase
DYI28_RS26360	COG1063	alcohol dehydrogenase
DYI28_RS26375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYI28_RS26380	COG2832	Protein of unknown function (DUF454)
DYI28_RS26390	COG0602	queuosine metabolic process
DYI28_RS26395	COG0247	lactate metabolic process
DYI28_RS26400	COG1139	Iron-sulfur cluster binding protein
DYI28_RS26410	COG0351	phosphomethylpyrimidine kinase
DYI28_RS26415	COG1629	transport
DYI28_RS26430	COG4589	Belongs to the CDS family
DYI28_RS26440	COG2304	oxidoreductase activity
DYI28_RS26450	COG1393	Belongs to the ArsC family
DYI28_RS26460	COG4771	TonB-dependent receptor
DYI28_RS26475	COG2233	PERMEase
DYI28_RS26480	COG1509	lysine 2,3-aminomutase activity
DYI28_RS26495	COG1115	amino acid carrier protein
DYI28_RS26530	COG1285	pathogenesis
DYI28_RS26550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYI28_RS26555	COG1388	LysM domain
DYI28_RS26555	COG0741	lytic transglycosylase activity
DYI28_RS26595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYI28_RS26605	COG0534	Mate efflux family protein
DYI28_RS26615	COG0564	pseudouridine synthase activity
DYI28_RS26645	COG0346	lactoylglutathione lyase activity
DYI28_RS26655	COG0653	protein targeting
DYI28_RS26680	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYI28_RS26685	COG0732	type I restriction modification DNA specificity domain
DYI28_RS26705	COG1401	restriction endodeoxyribonuclease activity
DYI28_RS26710	COG4268	DNA restriction-modification system
DYI28_RS26730	COG4771	TonB-dependent receptor
DYI28_RS26770	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYI28_RS26775	COG1063	alcohol dehydrogenase
DYI28_RS26790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DYI28_RS26795	COG0784	Response regulator, receiver
DYI28_RS26795	COG2205	protein histidine kinase activity
DYI28_RS26800	COG0702	epimerase
DYI28_RS26810	COG4864	UPF0365 protein
DYI28_RS26825	COG0037	tRNA processing
DYI28_RS26835	COG1477	protein flavinylation
DYI28_RS26840	COG1971	Probably functions as a manganese efflux pump
DYI28_RS26855	COG0463	Glycosyl transferase, family 2
DYI28_RS26875	COG0148	phosphopyruvate hydratase activity
DYI28_RS26885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYI28_RS26890	COG1082	Xylose isomerase domain protein TIM barrel
DYI28_RS26895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DYI28_RS26900	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYI28_RS26905	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DYI28_RS26910	COG4651	solute:proton antiporter activity
DYI28_RS26910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYI28_RS26920	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DYI28_RS26925	COG0193	aminoacyl-tRNA hydrolase activity
DYI28_RS26930	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYI28_RS26940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DYI28_RS26955	COG0237	dephospho-CoA kinase activity
DYI28_RS26970	COG0542	response to heat
DYI28_RS26980	COG0583	DNA-binding transcription factor activity
DYI28_RS27010	COG2855	membrane
DYI28_RS27015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYI28_RS27020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYI28_RS27045	COG0443	Heat shock 70 kDa protein
DYI28_RS27055	COG4651	solute:proton antiporter activity
DYI28_RS27055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYI28_RS27060	COG0306	phosphate transporter
DYI28_RS27070	COG0586	Pfam SNARE associated Golgi protein
DYI28_RS27130	COG0038	chloride channel
DYI28_RS27140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DYI28_RS27165	COG3119	arylsulfatase activity
DYI28_RS27175	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYI28_RS27180	COG0702	epimerase
DYI28_RS27185	COG4771	TonB-dependent receptor
DYI28_RS27195	COG5434	Belongs to the glycosyl hydrolase 28 family
DYI28_RS27205	COG0745	RESPONSE REGULATOR receiver
DYI28_RS27205	COG3292	Two component regulator propeller
DYI28_RS27205	COG2205	protein histidine kinase activity
DYI28_RS27210	COG2172	sigma factor antagonist activity
DYI28_RS27235	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DYI28_RS27240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYI28_RS27255	COG2843	Capsule synthesis protein
DYI28_RS27270	COG3250	beta-galactosidase activity
DYI28_RS27285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS27290	COG4206	TonB-dependent receptor
DYI28_RS27290	COG1629	transport
DYI28_RS27300	COG2205	protein histidine kinase activity
DYI28_RS27300	COG3292	Two component regulator propeller
DYI28_RS27300	COG0745	RESPONSE REGULATOR receiver
DYI28_RS27345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DYI28_RS27350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYI28_RS27360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI28_RS27365	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DYI28_RS27425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYI28_RS27460	COG1760	l-serine dehydratase
DYI28_RS27465	COG0598	Magnesium transport protein CorA
DYI28_RS27470	COG1193	negative regulation of DNA recombination
DYI28_RS27480	COG2873	o-acetylhomoserine
DYI28_RS27495	COG2197	response regulator
DYI28_RS27500	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DYI28_RS27505	COG0456	acetyltransferase
DYI28_RS27515	COG3189	MarR family transcriptional regulator
DYI28_RS27520	COG0561	phosphatase activity
DYI28_RS27525	COG1169	isochorismate synthase
DYI28_RS27530	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DYI28_RS27535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DYI28_RS27540	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS27565	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DYI28_RS27570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYI28_RS27585	COG4771	TonB-dependent receptor
DYI28_RS27590	COG0702	epimerase
DYI28_RS27610	COG1472	Belongs to the glycosyl hydrolase 3 family
DYI28_RS27620	COG0110	maltose O-acetyltransferase activity
DYI28_RS27655	COG4771	TonB-dependent receptor
DYI28_RS27675	COG1819	glycosyl
DYI28_RS27680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DYI28_RS27690	COG1690	Belongs to the RtcB family
DYI28_RS27715	COG1620	l-lactate permease
DYI28_RS27730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYI28_RS27735	COG0439	Biotin carboxylase
DYI28_RS27740	COG0511	ligase activity, forming carbon-carbon bonds
DYI28_RS27745	COG0784	Response regulator, receiver
DYI28_RS27745	COG2205	protein histidine kinase activity
DYI28_RS27760	COG2226	methyltransferase
DYI28_RS27775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYI28_RS27775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DYI28_RS27785	COG4771	TonB-dependent receptor
DYI28_RS27795	COG2223	nitrite transmembrane transporter activity
DYI28_RS27810	COG1609	Transcriptional regulator
DYI28_RS27815	COG1028	Short-chain dehydrogenase reductase Sdr
DYI28_RS27820	COG1312	Catalyzes the dehydration of D-mannonate
DYI28_RS27865	COG1162	GTPase activity
DYI28_RS27935	COG4771	TonB-dependent receptor
DYI28_RS27940	COG0702	epimerase
DYI28_RS27970	COG4771	TonB-dependent receptor
DYI28_RS27985	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
DYI28_RS27995	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DYI28_RS28005	COG0778	Nitroreductase
DYI28_RS28010	COG0656	L-ascorbic acid biosynthetic process
DYI28_RS28015	COG2814	Major facilitator Superfamily
DYI28_RS28035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DYI28_RS28060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYI28_RS28075	COG2814	Major facilitator Superfamily
DYI28_RS28095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYI28_RS28105	COG1328	CTP reductase activity
DYI28_RS28105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYI28_RS28110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYI28_RS28110	COG2885	chlorophyll binding
DYI28_RS28115	COG3831	ATPase activity
DYI28_RS28115	COG4884	unkown
DYI28_RS28130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYI28_RS28140	COG0534	Mate efflux family protein
DYI28_RS28165	COG1924	4 iron, 4 sulfur cluster binding
DYI28_RS28205	COG0456	acetyltransferase
DYI28_RS28220	COG0788	formyltetrahydrofolate deformylase activity
DYI28_RS28225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DYI28_RS28230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DYI28_RS28235	COG0107	imidazoleglycerol-phosphate synthase activity
DYI28_RS28240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DYI28_RS28240	COG0140	phosphoribosyl-ATP diphosphatase activity
DYI28_RS28245	COG2884	Cell division ATP-binding protein ftsE
DYI28_RS28250	COG0527	aspartate kinase activity
DYI28_RS28255	COG0019	diaminopimelate decarboxylase activity
DYI28_RS28275	COG0156	8-amino-7-oxononanoate synthase activity
DYI28_RS28280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DYI28_RS28290	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DYI28_RS28295	COG0321	lipoyl(octanoyl) transferase activity
DYI28_RS28295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DYI28_RS28310	COG0592	DNA-directed DNA polymerase activity
DYI28_RS28325	COG0497	DNA recombination
DYI28_RS28330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYI28_RS28380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DYI28_RS28390	COG1216	Glycosyl transferase, family 2
DYI28_RS28415	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DYI28_RS28430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYI28_RS28440	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYI28_RS28510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DYI28_RS28515	COG0167	dihydroorotate dehydrogenase activity
DYI28_RS28520	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYI28_RS28535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DYI28_RS28545	COG0586	Pfam SNARE associated Golgi protein
DYI28_RS28555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYI28_RS28565	COG0573	inorganic phosphate transmembrane transporter activity
DYI28_RS28570	COG0581	inorganic phosphate transmembrane transporter activity
DYI28_RS28575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DYI28_RS28580	COG0704	Plays a role in the regulation of phosphate uptake
DYI28_RS28590	COG0778	Nitroreductase
DYI28_RS28600	COG1295	ribonuclease BN
DYI28_RS28615	COG4948	Mandelate Racemase Muconate Lactonizing
DYI28_RS28620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYI28_RS28625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYI28_RS28690	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DYI28_RS28710	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DYI28_RS28720	COG0058	SHG alpha-glucan phosphorylase activity
DYI28_RS28725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYI28_RS28730	COG3842	ATPase activity
DYI28_RS28735	COG1176	ABC-type spermidine putrescine transport system, permease component I
DYI28_RS28740	COG1177	transmembrane transport
DYI28_RS28800	COG0738	Major facilitator superfamily
DYI28_RS28810	COG1070	Carbohydrate kinase
DYI28_RS28820	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
DYI28_RS28830	COG0228	four-way junction DNA binding
DYI28_RS28840	COG0784	Response regulator, receiver
DYI28_RS28840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYI28_RS28840	COG2198	Histidine kinase
DYI28_RS28840	COG2205	protein histidine kinase activity
DYI28_RS28855	COG1733	regulation of RNA biosynthetic process
DYI28_RS28865	COG4452	Inner membrane protein CreD
DYI28_RS28900	COG2721	sulfolactate sulfo-lyase activity
DYI28_RS28905	COG1609	Transcriptional regulator
DYI28_RS28940	COG4771	TonB-dependent receptor
DYI28_RS28990	COG4804	nuclease activity
DYI28_RS29005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYI28_RS29005	COG0551	DNA topoisomerase type I activity
DYI28_RS29020	COG4974	Belongs to the 'phage' integrase family
DYI28_RS29725	COG2890	protein-(glutamine-N5) methyltransferase activity
DYI28_RS29725	COG0009	L-threonylcarbamoyladenylate synthase
DYI28_RS29890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DYI28_RS29955	COG1196	nuclear chromosome segregation
DYI28_RS29955	COG0741	lytic transglycosylase activity
DYI28_RS29955	COG0739	heme binding
DYI28_RS30000	COG0776	regulation of translation
DYI28_RS30120	COG4227	nucleotidyltransferase activity