locus-tag	class	description
NXW12_RS00020	COG0436	Aminotransferase
NXW12_RS00025	COG0577	efflux transmembrane transporter activity
NXW12_RS00025	COG1136	(ABC) transporter
NXW12_RS00030	COG0189	ligase activity
NXW12_RS00030	COG0569	domain protein
NXW12_RS00035	COG0456	acetyltransferase
NXW12_RS00040	COG1215	transferase activity, transferring glycosyl groups
NXW12_RS00045	COG0628	permease
NXW12_RS00050	COG3852	Histidine kinase
NXW12_RS00070	COG1136	(ABC) transporter
NXW12_RS00070	COG0577	efflux transmembrane transporter activity
NXW12_RS00075	COG0577	efflux transmembrane transporter activity
NXW12_RS00075	COG1136	(ABC) transporter
NXW12_RS00085	COG0110	maltose O-acetyltransferase activity
NXW12_RS00120	COG4771	TonB-dependent receptor
NXW12_RS00175	COG1620	l-lactate permease
NXW12_RS00180	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW12_RS00285	COG0740	serine-type endopeptidase activity
NXW12_RS00420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW12_RS00425	COG0439	Biotin carboxylase
NXW12_RS00430	COG0511	ligase activity, forming carbon-carbon bonds
NXW12_RS00445	COG2226	methyltransferase
NXW12_RS00470	COG4771	TonB-dependent receptor
NXW12_RS00485	COG2223	nitrite transmembrane transporter activity
NXW12_RS00500	COG1609	Transcriptional regulator
NXW12_RS00505	COG1028	Short-chain dehydrogenase reductase Sdr
NXW12_RS00510	COG1312	Catalyzes the dehydration of D-mannonate
NXW12_RS00555	COG1162	GTPase activity
NXW12_RS00580	COG4771	TonB-dependent receptor
NXW12_RS00595	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXW12_RS00605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXW12_RS00615	COG0778	Nitroreductase
NXW12_RS00620	COG0656	L-ascorbic acid biosynthetic process
NXW12_RS00625	COG2814	Major facilitator Superfamily
NXW12_RS00645	COG0655	NAD(P)H dehydrogenase (quinone) activity
NXW12_RS00670	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXW12_RS00685	COG2814	Major facilitator Superfamily
NXW12_RS00705	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXW12_RS00715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXW12_RS00715	COG1328	CTP reductase activity
NXW12_RS00720	COG2885	chlorophyll binding
NXW12_RS00720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS00725	COG3831	ATPase activity
NXW12_RS00725	COG4884	unkown
NXW12_RS00740	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXW12_RS00750	COG0534	Mate efflux family protein
NXW12_RS00775	COG1924	4 iron, 4 sulfur cluster binding
NXW12_RS00785	COG3547	Transposase (IS116 IS110 IS902 family)
NXW12_RS00810	COG0456	acetyltransferase
NXW12_RS00825	COG0788	formyltetrahydrofolate deformylase activity
NXW12_RS00830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXW12_RS00835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXW12_RS00840	COG0107	imidazoleglycerol-phosphate synthase activity
NXW12_RS00845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXW12_RS00845	COG0140	phosphoribosyl-ATP diphosphatase activity
NXW12_RS00850	COG2884	Cell division ATP-binding protein ftsE
NXW12_RS00855	COG0527	aspartate kinase activity
NXW12_RS00860	COG0019	diaminopimelate decarboxylase activity
NXW12_RS00880	COG0156	8-amino-7-oxononanoate synthase activity
NXW12_RS00885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW12_RS00900	COG0321	lipoyl(octanoyl) transferase activity
NXW12_RS00900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXW12_RS00915	COG0592	DNA-directed DNA polymerase activity
NXW12_RS00930	COG0497	DNA recombination
NXW12_RS00935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXW12_RS00970	COG1083	cytidylyl-transferase
NXW12_RS00980	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NXW12_RS00995	COG0110	maltose O-acetyltransferase activity
NXW12_RS01025	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS01045	COG3344	reverse transcriptase
NXW12_RS01085	COG3328	transposase activity
NXW12_RS01130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXW12_RS01135	COG0167	dihydroorotate dehydrogenase activity
NXW12_RS01140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXW12_RS01155	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXW12_RS01165	COG0586	Pfam SNARE associated Golgi protein
NXW12_RS01175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXW12_RS01185	COG0573	inorganic phosphate transmembrane transporter activity
NXW12_RS01190	COG0581	inorganic phosphate transmembrane transporter activity
NXW12_RS01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXW12_RS01200	COG0704	Plays a role in the regulation of phosphate uptake
NXW12_RS01230	COG0582	viral genome integration into host DNA
NXW12_RS01265	COG0778	Nitroreductase
NXW12_RS01275	COG1295	ribonuclease BN
NXW12_RS01290	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS01295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXW12_RS01300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXW12_RS01330	COG4771	TonB-dependent receptor
NXW12_RS01340	COG1629	transport
NXW12_RS01345	COG0702	epimerase
NXW12_RS01355	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS01420	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXW12_RS01440	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW12_RS01450	COG0058	SHG alpha-glucan phosphorylase activity
NXW12_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW12_RS01465	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXW12_RS01470	COG1177	transmembrane transport
NXW12_RS01530	COG0738	Major facilitator superfamily
NXW12_RS01540	COG1070	Carbohydrate kinase
NXW12_RS01550	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXW12_RS01560	COG0228	four-way junction DNA binding
NXW12_RS01580	COG1733	regulation of RNA biosynthetic process
NXW12_RS01605	COG4452	Inner membrane protein CreD
NXW12_RS01620	COG2721	sulfolactate sulfo-lyase activity
NXW12_RS01625	COG1609	Transcriptional regulator
NXW12_RS01685	COG1230	cation diffusion facilitator family transporter
NXW12_RS01690	COG0490	domain, Protein
NXW12_RS01690	COG2985	domain, Protein
NXW12_RS01700	COG4771	TonB-dependent receptor
NXW12_RS01710	COG4771	TonB-dependent receptor
NXW12_RS01725	COG2375	cellular response to nickel ion
NXW12_RS01725	COG1132	(ABC) transporter
NXW12_RS01730	COG1132	(ABC) transporter
NXW12_RS01745	COG1333	cytochrome c biogenesis protein
NXW12_RS01745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXW12_RS01770	COG3487	Iron-regulated protein
NXW12_RS01775	COG1730	sister chromatid segregation
NXW12_RS01800	COG2197	response regulator
NXW12_RS01815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXW12_RS01820	COG0745	RESPONSE REGULATOR receiver
NXW12_RS01840	COG0159	tryptophan synthase activity
NXW12_RS01845	COG0135	phosphoribosylanthranilate isomerase activity
NXW12_RS01850	COG0134	indole-3-glycerol-phosphate synthase activity
NXW12_RS01855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXW12_RS01870	COG0133	tryptophan synthase activity
NXW12_RS01880	COG1979	alcohol dehydrogenase
NXW12_RS01890	COG0471	metal ion transport
NXW12_RS01890	COG0490	domain, Protein
NXW12_RS01910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXW12_RS01925	COG0004	ammonium transporteR
NXW12_RS01930	COG0347	Belongs to the P(II) protein family
NXW12_RS01940	COG0436	Aminotransferase
NXW12_RS01945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXW12_RS01975	COG0367	asparagine synthase
NXW12_RS01990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXW12_RS02000	COG0505	Belongs to the CarA family
NXW12_RS02005	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXW12_RS02040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXW12_RS02105	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW12_RS02125	COG1917	Cupin 2, conserved barrel domain protein
NXW12_RS02125	COG2207	Transcriptional regulator
NXW12_RS02135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW12_RS02140	COG1131	(ABC) transporter
NXW12_RS02145	COG0842	Transport permease protein
NXW12_RS02150	COG0842	Transport permease protein
NXW12_RS02160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXW12_RS02170	COG2949	membrane
NXW12_RS02180	COG0556	nucleotide-excision repair
NXW12_RS02185	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXW12_RS02215	COG1388	LysM domain
NXW12_RS02215	COG3942	CHAP domain
NXW12_RS02225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXW12_RS02230	COG3104	oligopeptide transport
NXW12_RS02245	COG1983	PspC domain protein
NXW12_RS02260	COG1506	peptidase
NXW12_RS02260	COG0823	Involved in the tonB-independent uptake of proteins
NXW12_RS02265	COG0534	Mate efflux family protein
NXW12_RS02270	COG0706	membrane insertase activity
NXW12_RS02275	COG0504	CTP synthase activity
NXW12_RS02305	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXW12_RS02315	COG1086	Polysaccharide biosynthesis protein
NXW12_RS02385	COG0110	maltose O-acetyltransferase activity
NXW12_RS02390	COG0438	transferase activity, transferring glycosyl groups
NXW12_RS02400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW12_RS02475	COG4656	Part of a membrane complex involved in electron transport
NXW12_RS02480	COG4658	electron transport chain
NXW12_RS02485	COG4659	FMN binding
NXW12_RS02490	COG4660	Part of a membrane complex involved in electron transport
NXW12_RS02495	COG4657	Part of a membrane complex involved in electron transport
NXW12_RS02500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXW12_RS02505	COG4680	protein conserved in bacteria
NXW12_RS02515	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXW12_RS02520	COG0305	Participates in initiation and elongation during chromosome replication
NXW12_RS02525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW12_RS02525	COG0072	phenylalanine-tRNA ligase activity
NXW12_RS02530	COG0217	transcriptional regulatory protein
NXW12_RS02545	COG0708	Exodeoxyribonuclease III
NXW12_RS02550	COG0432	Pfam Uncharacterised protein family UPF0047
NXW12_RS02570	COG0481	GTPase activity
NXW12_RS02585	COG0024	Methionine aminopeptidase
NXW12_RS02605	COG0564	pseudouridine synthase activity
NXW12_RS02610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXW12_RS02615	COG0574	Belongs to the PEP-utilizing enzyme family
NXW12_RS02615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXW12_RS02630	COG0352	thiamine-phosphate diphosphorylase activity
NXW12_RS02635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXW12_RS02645	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXW12_RS02650	COG2022	thiamine diphosphate biosynthetic process
NXW12_RS02655	COG0352	thiamine-phosphate diphosphorylase activity
NXW12_RS02665	COG5002	protein histidine kinase activity
NXW12_RS02795	COG0681	Belongs to the peptidase S26 family
NXW12_RS02845	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXW12_RS02895	COG3118	belongs to the thioredoxin family
NXW12_RS02915	COG5002	protein histidine kinase activity
NXW12_RS02920	COG0745	RESPONSE REGULATOR receiver
NXW12_RS02925	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
NXW12_RS02940	COG2233	PERMEase
NXW12_RS02955	COG4191	Histidine kinase
NXW12_RS02960	COG2204	response regulator
NXW12_RS02980	COG0577	efflux transmembrane transporter activity
NXW12_RS02980	COG1136	(ABC) transporter
NXW12_RS02995	COG1011	Hydrolase
NXW12_RS03000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXW12_RS03010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXW12_RS03045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXW12_RS03145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NXW12_RS03145	COG2755	lipolytic protein G-D-S-L family
NXW12_RS03150	COG0454	-acetyltransferase
NXW12_RS03155	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXW12_RS03160	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXW12_RS03165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXW12_RS03175	COG0356	it plays a direct role in the translocation of protons across the membrane
NXW12_RS03180	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW12_RS03185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXW12_RS03190	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW12_RS03195	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXW12_RS03200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXW12_RS03205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW12_RS03210	COG2431	L-lysine efflux transmembrane transporter activity
NXW12_RS03220	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXW12_RS03220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW12_RS03225	COG1690	Belongs to the RtcB family
NXW12_RS03235	COG2207	Transcriptional regulator
NXW12_RS03280	COG2985	domain, Protein
NXW12_RS03285	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXW12_RS03290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXW12_RS03305	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXW12_RS03310	COG0540	Belongs to the ATCase OTCase family
NXW12_RS03330	COG4974	Belongs to the 'phage' integrase family
NXW12_RS03445	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NXW12_RS03455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXW12_RS03475	COG2205	protein histidine kinase activity
NXW12_RS03500	COG1629	transport
NXW12_RS03500	COG4206	TonB-dependent receptor
NXW12_RS03510	COG3119	arylsulfatase activity
NXW12_RS03515	COG3250	beta-galactosidase activity
NXW12_RS03520	COG2205	protein histidine kinase activity
NXW12_RS03525	COG1360	Flagellar Motor Protein
NXW12_RS03550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXW12_RS03565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXW12_RS03595	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXW12_RS03610	COG2326	polyphosphate kinase activity
NXW12_RS03615	COG0667	Aldo Keto reductase
NXW12_RS03650	COG3279	Response regulator of the LytR AlgR family
NXW12_RS03655	COG0724	RNA recognition motif
NXW12_RS03670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXW12_RS03675	COG0045	succinate-CoA ligase (ADP-forming) activity
NXW12_RS03680	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXW12_RS03685	COG0351	phosphomethylpyrimidine kinase
NXW12_RS03700	COG2115	Belongs to the xylose isomerase family
NXW12_RS03705	COG0477	Major facilitator Superfamily
NXW12_RS03705	COG2814	Major facilitator Superfamily
NXW12_RS03745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXW12_RS03755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXW12_RS03770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXW12_RS03800	COG3015	lipoprotein NlpE involved in copper resistance
NXW12_RS03820	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXW12_RS03835	COG1904	glucuronate isomerase
NXW12_RS03840	COG1609	Transcriptional regulator
NXW12_RS03845	COG0246	Mannitol dehydrogenase
NXW12_RS03875	COG0513	Belongs to the DEAD box helicase family
NXW12_RS03880	COG3830	Belongs to the UPF0237 family
NXW12_RS03880	COG0560	Phosphoserine phosphatase
NXW12_RS03900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXW12_RS03905	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXW12_RS03925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXW12_RS03970	COG0156	8-amino-7-oxononanoate synthase activity
NXW12_RS03975	COG1597	lipid kinase activity
NXW12_RS03980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXW12_RS04010	COG1132	(ABC) transporter
NXW12_RS04035	COG1595	DNA-templated transcription, initiation
NXW12_RS04040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXW12_RS04055	COG1538	Outer membrane efflux protein
NXW12_RS04075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXW12_RS04090	COG0543	2 iron, 2 sulfur cluster binding
NXW12_RS04095	COG0167	dihydroorotate dehydrogenase activity
NXW12_RS04100	COG0336	Belongs to the RNA methyltransferase TrmD family
NXW12_RS04105	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXW12_RS04110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXW12_RS04150	COG0326	Molecular chaperone. Has ATPase activity
NXW12_RS04200	COG2304	oxidoreductase activity
NXW12_RS04215	COG0714	Associated with various cellular activities
NXW12_RS04225	COG0776	regulation of translation
NXW12_RS04230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW12_RS04250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXW12_RS04260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXW12_RS04295	COG2205	protein histidine kinase activity
NXW12_RS04300	COG0745	RESPONSE REGULATOR receiver
NXW12_RS04305	COG0442	prolyl-tRNA aminoacylation
NXW12_RS04340	COG0745	RESPONSE REGULATOR receiver
NXW12_RS04340	COG2205	protein histidine kinase activity
NXW12_RS04340	COG3292	Two component regulator propeller
NXW12_RS04340	COG0745	RESPONSE REGULATOR receiver
NXW12_RS04340	COG2205	protein histidine kinase activity
NXW12_RS04340	COG3292	Two component regulator propeller
NXW12_RS04350	COG4206	TonB-dependent receptor
NXW12_RS04390	COG1733	regulation of RNA biosynthetic process
NXW12_RS04420	COG1011	Hydrolase
NXW12_RS04425	COG0300	oxidoreductase activity
NXW12_RS04440	COG2966	Psort location CytoplasmicMembrane, score
NXW12_RS04470	COG0745	RESPONSE REGULATOR receiver
NXW12_RS04470	COG2205	protein histidine kinase activity
NXW12_RS04470	COG3292	Two component regulator propeller
NXW12_RS04475	COG3250	beta-galactosidase activity
NXW12_RS04575	COG5002	protein histidine kinase activity
NXW12_RS04580	COG0745	RESPONSE REGULATOR receiver
NXW12_RS04585	COG3250	beta-galactosidase activity
NXW12_RS04590	COG3250	beta-galactosidase activity
NXW12_RS04600	COG0784	Response regulator, receiver
NXW12_RS04600	COG2205	protein histidine kinase activity
NXW12_RS04610	COG3250	beta-galactosidase activity
NXW12_RS04625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXW12_RS04630	COG2814	Major facilitator Superfamily
NXW12_RS04635	COG2731	YhcH YjgK YiaL family protein
NXW12_RS04645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXW12_RS04655	COG3291	Pkd domain containing protein
NXW12_RS04680	COG4974	Belongs to the 'phage' integrase family
NXW12_RS04835	COG1475	DNA binding
NXW12_RS04855	COG1192	Involved in chromosome partitioning
NXW12_RS04860	COG0629	single-stranded DNA binding
NXW12_RS05020	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW12_RS05150	COG0542	response to heat
NXW12_RS05215	COG3209	COG3209 Rhs family protein
NXW12_RS05310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXW12_RS05315	COG0739	heme binding
NXW12_RS05315	COG0741	lytic transglycosylase activity
NXW12_RS05315	COG1196	nuclear chromosome segregation
NXW12_RS05385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS05395	COG3408	Glycogen debranching enzyme
NXW12_RS05440	COG3408	Glycogen debranching enzyme
NXW12_RS05475	COG0702	epimerase
NXW12_RS05480	COG1629	transport
NXW12_RS05480	COG4206	TonB-dependent receptor
NXW12_RS05495	COG3537	Alpha-1,2-mannosidase
NXW12_RS05500	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW12_RS05535	COG1629	transport
NXW12_RS05535	COG4206	TonB-dependent receptor
NXW12_RS05545	COG1629	transport
NXW12_RS05545	COG4206	TonB-dependent receptor
NXW12_RS05585	COG1074	ATP-dependent DNA helicase activity
NXW12_RS05605	COG0745	RESPONSE REGULATOR receiver
NXW12_RS05670	COG1475	DNA binding
NXW12_RS05675	COG3969	phosphoadenosine phosphosulfate
NXW12_RS05690	COG0305	Participates in initiation and elongation during chromosome replication
NXW12_RS05695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXW12_RS05750	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXW12_RS05785	COG0085	RNA polymerase activity
NXW12_RS05805	COG0629	single-stranded DNA binding
NXW12_RS05865	COG5410	chromosome segregation
NXW12_RS06025	COG1678	Uncharacterized ACR, COG1678
NXW12_RS06040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXW12_RS06050	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXW12_RS06070	COG0657	acetylesterase activity
NXW12_RS06070	COG2755	lipolytic protein G-D-S-L family
NXW12_RS06080	COG0321	lipoyl(octanoyl) transferase activity
NXW12_RS06090	COG2217	Heavy metal translocating P-type atpase
NXW12_RS06110	COG1408	metallophosphoesterase
NXW12_RS06125	COG0357	Ribosomal RNA small subunit methyltransferase G
NXW12_RS06130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXW12_RS06135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXW12_RS06135	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXW12_RS06140	COG0778	Nitroreductase
NXW12_RS06155	COG1739	Uncharacterized protein family UPF0029
NXW12_RS06170	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXW12_RS06175	COG0513	Belongs to the DEAD box helicase family
NXW12_RS06185	COG2871	sodium ion transport
NXW12_RS06200	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXW12_RS06205	COG1805	sodium ion transport
NXW12_RS06240	COG1215	transferase activity, transferring glycosyl groups
NXW12_RS06255	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS06300	COG1216	Glycosyl transferase, family 2
NXW12_RS06300	COG1442	glycosyl transferase family 8
NXW12_RS06305	COG2244	polysaccharide biosynthetic process
NXW12_RS06315	COG0438	transferase activity, transferring glycosyl groups
NXW12_RS06330	COG1368	sulfuric ester hydrolase activity
NXW12_RS06340	COG2205	protein histidine kinase activity
NXW12_RS06340	COG0784	Response regulator, receiver
NXW12_RS06350	COG4206	TonB-dependent receptor
NXW12_RS06350	COG1629	transport
NXW12_RS06355	COG0488	(ABC) transporter
NXW12_RS06365	COG0784	Response regulator, receiver
NXW12_RS06365	COG2205	protein histidine kinase activity
NXW12_RS06370	COG2755	lipolytic protein G-D-S-L family
NXW12_RS06370	COG0657	acetylesterase activity
NXW12_RS06375	COG0534	Mate efflux family protein
NXW12_RS06380	COG2885	chlorophyll binding
NXW12_RS06385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXW12_RS06390	COG1595	DNA-templated transcription, initiation
NXW12_RS06395	COG1704	LemA family
NXW12_RS06400	COG0501	Belongs to the peptidase M48B family
NXW12_RS06425	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXW12_RS06430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXW12_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW12_RS06460	COG1136	(ABC) transporter
NXW12_RS06465	COG0577	efflux transmembrane transporter activity
NXW12_RS06465	COG1136	(ABC) transporter
NXW12_RS06475	COG3279	Response regulator of the LytR AlgR family
NXW12_RS06590	COG1595	DNA-templated transcription, initiation
NXW12_RS06660	COG3728	DNA packaging
NXW12_RS06760	COG1475	DNA binding
NXW12_RS06785	COG1061	Type III restriction enzyme res subunit
NXW12_RS06800	COG0629	single-stranded DNA binding
NXW12_RS06895	COG2837	iron assimilation
NXW12_RS06900	COG0363	glucosamine-6-phosphate deaminase activity
NXW12_RS06905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXW12_RS06910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXW12_RS06915	COG1301	dicarboxylic acid transport
NXW12_RS06920	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXW12_RS06925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW12_RS06930	COG0318	PFAM AMP-dependent synthetase and ligase
NXW12_RS06950	COG2985	domain, Protein
NXW12_RS06950	COG0490	domain, Protein
NXW12_RS06965	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXW12_RS06995	COG0737	Belongs to the 5'-nucleotidase family
NXW12_RS07000	COG2202	Pas domain
NXW12_RS07000	COG2205	protein histidine kinase activity
NXW12_RS07055	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS07090	COG0488	(ABC) transporter
NXW12_RS07095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXW12_RS07100	COG0484	heat shock protein binding
NXW12_RS07105	COG4335	DNA alkylation repair
NXW12_RS07110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS07115	COG4771	TonB-dependent receptor
NXW12_RS07120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS07125	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS07150	COG1629	transport
NXW12_RS07215	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS07230	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS07255	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXW12_RS07265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXW12_RS07275	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXW12_RS07275	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXW12_RS07275	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXW12_RS07275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NXW12_RS07280	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXW12_RS07285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXW12_RS07295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXW12_RS07305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXW12_RS07310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXW12_RS07320	COG0242	peptide deformylase activity
NXW12_RS07325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXW12_RS07345	COG2895	sulfate adenylyltransferase (ATP) activity
NXW12_RS07350	COG0175	sulfate reduction
NXW12_RS07355	COG0529	Catalyzes the synthesis of activated sulfate
NXW12_RS07360	COG3273	potassium ion transport
NXW12_RS07360	COG0471	metal ion transport
NXW12_RS07365	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXW12_RS07375	COG4221	oxidoreductase activity
NXW12_RS07415	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXW12_RS07420	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NXW12_RS07445	COG1216	Glycosyl transferase, family 2
NXW12_RS07445	COG1442	glycosyl transferase family 8
NXW12_RS07485	COG1442	glycosyl transferase family 8
NXW12_RS07485	COG1216	Glycosyl transferase, family 2
NXW12_RS07510	COG1216	Glycosyl transferase, family 2
NXW12_RS07535	COG0489	protein tyrosine kinase activity
NXW12_RS07595	COG4974	Belongs to the 'phage' integrase family
NXW12_RS07600	COG1482	cell wall glycoprotein biosynthetic process
NXW12_RS07615	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXW12_RS07635	COG2816	NAD+ diphosphatase activity
NXW12_RS07645	COG2160	L-arabinose isomerase activity
NXW12_RS07650	COG1070	Carbohydrate kinase
NXW12_RS07670	COG0698	ribose 5-phosphate isomerase
NXW12_RS07675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NXW12_RS07690	COG5012	cobalamin binding
NXW12_RS07695	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW12_RS07770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXW12_RS07775	COG0673	inositol 2-dehydrogenase activity
NXW12_RS07780	COG0590	tRNA wobble adenosine to inosine editing
NXW12_RS07800	COG2264	protein methyltransferase activity
NXW12_RS07815	COG0022	dehydrogenase e1 component
NXW12_RS07820	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXW12_RS07860	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXW12_RS07880	COG4974	Belongs to the 'phage' integrase family
NXW12_RS07895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXW12_RS07920	COG1032	radical SAM domain protein
NXW12_RS07930	COG0463	Glycosyl transferase, family 2
NXW12_RS07940	COG0646	methionine synthase
NXW12_RS07940	COG1410	methionine synthase
NXW12_RS07990	COG0641	radical SAM
NXW12_RS07995	COG3591	Belongs to the peptidase S1B family
NXW12_RS08015	COG3118	belongs to the thioredoxin family
NXW12_RS08030	COG1773	rubredoxin
NXW12_RS08030	COG1592	Rubrerythrin
NXW12_RS08080	COG4206	TonB-dependent receptor
NXW12_RS08080	COG1629	transport
NXW12_RS08085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXW12_RS08085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXW12_RS08100	COG0131	Imidazoleglycerol-phosphate dehydratase
NXW12_RS08105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXW12_RS08110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXW12_RS08135	COG2271	Major facilitator Superfamily
NXW12_RS08160	COG0702	epimerase
NXW12_RS08165	COG4771	TonB-dependent receptor
NXW12_RS08180	COG1741	Belongs to the pirin family
NXW12_RS08185	COG4232	protein-disulfide reductase activity
NXW12_RS08195	COG0572	uridine kinase
NXW12_RS08200	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXW12_RS08205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXW12_RS08215	COG0778	Nitroreductase
NXW12_RS08220	COG1410	methionine synthase
NXW12_RS08220	COG0646	methionine synthase
NXW12_RS08225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXW12_RS08300	COG2003	Belongs to the UPF0758 family
NXW12_RS08355	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW12_RS08365	COG4953	penicillin-binding protein 1C
NXW12_RS08370	COG2814	Major facilitator Superfamily
NXW12_RS08380	COG1757	Na H antiporter
NXW12_RS08390	COG2197	response regulator
NXW12_RS08395	COG0482	sulfurtransferase activity
NXW12_RS08400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXW12_RS08425	COG0501	Belongs to the peptidase M48B family
NXW12_RS08430	COG1253	flavin adenine dinucleotide binding
NXW12_RS08445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS08460	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW12_RS08545	COG0740	serine-type endopeptidase activity
NXW12_RS08705	COG0551	DNA topoisomerase type I activity
NXW12_RS08705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW12_RS08740	COG3344	reverse transcriptase
NXW12_RS08890	COG2003	Belongs to the UPF0758 family
NXW12_RS08905	COG4974	Belongs to the 'phage' integrase family
NXW12_RS08920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXW12_RS08925	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS08970	COG2271	Major facilitator Superfamily
NXW12_RS08985	COG0584	glycerophosphoryl diester phosphodiesterase
NXW12_RS08995	COG4771	TonB-dependent receptor
NXW12_RS09005	COG1595	DNA-templated transcription, initiation
NXW12_RS09025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXW12_RS09030	COG0583	DNA-binding transcription factor activity
NXW12_RS09035	COG0783	Belongs to the Dps family
NXW12_RS09060	COG4771	TonB-dependent receptor
NXW12_RS09120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NXW12_RS09120	COG0515	serine threonine protein kinase
NXW12_RS09140	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS09145	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXW12_RS09150	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXW12_RS09155	COG1169	isochorismate synthase
NXW12_RS09160	COG0561	phosphatase activity
NXW12_RS09165	COG3189	MarR family transcriptional regulator
NXW12_RS09175	COG0456	acetyltransferase
NXW12_RS09180	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXW12_RS09185	COG2197	response regulator
NXW12_RS09195	COG4206	TonB-dependent receptor
NXW12_RS09195	COG1629	transport
NXW12_RS09200	COG2873	o-acetylhomoserine
NXW12_RS09220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXW12_RS09240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW12_RS09240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW12_RS09260	COG3547	Transposase (IS116 IS110 IS902 family)
NXW12_RS09270	COG3344	reverse transcriptase
NXW12_RS09385	COG4974	Belongs to the 'phage' integrase family
NXW12_RS09395	COG1193	negative regulation of DNA recombination
NXW12_RS09400	COG0598	Magnesium transport protein CorA
NXW12_RS09405	COG1760	l-serine dehydratase
NXW12_RS09420	COG1215	transferase activity, transferring glycosyl groups
NXW12_RS09430	COG0438	transferase activity, transferring glycosyl groups
NXW12_RS09440	COG1216	Glycosyl transferase, family 2
NXW12_RS09525	COG3292	Two component regulator propeller
NXW12_RS09525	COG2205	protein histidine kinase activity
NXW12_RS09525	COG0745	RESPONSE REGULATOR receiver
NXW12_RS09535	COG1629	transport
NXW12_RS09535	COG4206	TonB-dependent receptor
NXW12_RS09540	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS09555	COG3250	beta-galactosidase activity
NXW12_RS09575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXW12_RS09580	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXW12_RS09585	COG3292	Two component regulator propeller
NXW12_RS09585	COG0745	RESPONSE REGULATOR receiver
NXW12_RS09585	COG2205	protein histidine kinase activity
NXW12_RS09590	COG5434	Belongs to the glycosyl hydrolase 28 family
NXW12_RS09600	COG4771	TonB-dependent receptor
NXW12_RS09605	COG0702	epimerase
NXW12_RS09610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS09620	COG3119	arylsulfatase activity
NXW12_RS09630	COG1940	carbohydrate kinase activity
NXW12_RS09645	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXW12_RS09710	COG0586	Pfam SNARE associated Golgi protein
NXW12_RS09720	COG0306	phosphate transporter
NXW12_RS09725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW12_RS09725	COG4651	solute:proton antiporter activity
NXW12_RS09835	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS09900	COG0740	serine-type endopeptidase activity
NXW12_RS10060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXW12_RS10080	COG0443	Heat shock 70 kDa protein
NXW12_RS10100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXW12_RS10105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXW12_RS10110	COG2855	membrane
NXW12_RS10135	COG0583	DNA-binding transcription factor activity
NXW12_RS10145	COG0542	response to heat
NXW12_RS10160	COG0237	dephospho-CoA kinase activity
NXW12_RS10175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXW12_RS10185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXW12_RS10190	COG0193	aminoacyl-tRNA hydrolase activity
NXW12_RS10195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXW12_RS10205	COG4651	solute:proton antiporter activity
NXW12_RS10205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW12_RS10210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXW12_RS10215	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW12_RS10220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXW12_RS10225	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS10240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXW12_RS10250	COG0148	phosphopyruvate hydratase activity
NXW12_RS10270	COG0463	Glycosyl transferase, family 2
NXW12_RS10285	COG1971	Probably functions as a manganese efflux pump
NXW12_RS10290	COG1477	protein flavinylation
NXW12_RS10300	COG0037	tRNA processing
NXW12_RS10315	COG4864	UPF0365 protein
NXW12_RS10325	COG0702	epimerase
NXW12_RS10340	COG3547	Transposase (IS116 IS110 IS902 family)
NXW12_RS10365	COG1063	alcohol dehydrogenase
NXW12_RS10380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXW12_RS10390	COG0582	viral genome integration into host DNA
NXW12_RS10405	COG1396	sequence-specific DNA binding
NXW12_RS10455	COG0346	lactoylglutathione lyase activity
NXW12_RS10485	COG0564	pseudouridine synthase activity
NXW12_RS10495	COG0534	Mate efflux family protein
NXW12_RS10505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXW12_RS10550	COG1388	LysM domain
NXW12_RS10550	COG0741	lytic transglycosylase activity
NXW12_RS10555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXW12_RS10565	COG1285	pathogenesis
NXW12_RS10590	COG1115	amino acid carrier protein
NXW12_RS10600	COG1509	lysine 2,3-aminomutase activity
NXW12_RS10605	COG2233	PERMEase
NXW12_RS10620	COG4771	TonB-dependent receptor
NXW12_RS10630	COG1393	Belongs to the ArsC family
NXW12_RS10640	COG2304	oxidoreductase activity
NXW12_RS10650	COG4589	Belongs to the CDS family
NXW12_RS10665	COG1629	transport
NXW12_RS10675	COG0351	phosphomethylpyrimidine kinase
NXW12_RS10685	COG1139	Iron-sulfur cluster binding protein
NXW12_RS10690	COG0247	lactate metabolic process
NXW12_RS10695	COG0602	queuosine metabolic process
NXW12_RS10705	COG2832	Protein of unknown function (DUF454)
NXW12_RS10710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXW12_RS10720	COG1063	alcohol dehydrogenase
NXW12_RS10730	COG0246	Mannitol dehydrogenase
NXW12_RS10765	COG0702	epimerase
NXW12_RS10770	COG4771	TonB-dependent receptor
NXW12_RS10810	COG1418	mRNA catabolic process
NXW12_RS10815	COG3142	Participates in the control of copper homeostasis
NXW12_RS10910	COG2706	6-phosphogluconolactonase activity
NXW12_RS10915	COG0739	heme binding
NXW12_RS10925	COG1496	oxidoreductase activity
NXW12_RS10930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXW12_RS10935	COG0563	adenylate kinase activity
NXW12_RS10940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXW12_RS10955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXW12_RS10955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXW12_RS10995	COG2204	response regulator
NXW12_RS11000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXW12_RS11010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXW12_RS11025	COG1253	flavin adenine dinucleotide binding
NXW12_RS11045	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXW12_RS11055	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXW12_RS11060	COG0653	protein targeting
NXW12_RS11085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS11090	COG1629	transport
NXW12_RS11090	COG4206	TonB-dependent receptor
NXW12_RS11100	COG1595	DNA-templated transcription, initiation
NXW12_RS11115	COG3408	Glycogen debranching enzyme
NXW12_RS11120	COG3119	arylsulfatase activity
NXW12_RS11125	COG3119	arylsulfatase activity
NXW12_RS11135	COG0702	epimerase
NXW12_RS11140	COG4771	TonB-dependent receptor
NXW12_RS11150	COG1595	DNA-templated transcription, initiation
NXW12_RS11155	COG0784	Response regulator, receiver
NXW12_RS11155	COG2205	protein histidine kinase activity
NXW12_RS11160	COG0525	valine-tRNA ligase activity
NXW12_RS11175	COG3956	TIGRFAM MazG family protein
NXW12_RS11195	COG2989	Protein conserved in bacteria
NXW12_RS11200	COG1234	tRNA 3'-trailer cleavage
NXW12_RS11210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXW12_RS11210	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXW12_RS11250	COG4206	TonB-dependent receptor
NXW12_RS11250	COG1629	transport
NXW12_RS11290	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS11295	COG0492	ferredoxin-NADP+ reductase activity
NXW12_RS11305	COG1674	ftsk spoiiie
NXW12_RS11320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXW12_RS11325	COG2211	Major facilitator Superfamily
NXW12_RS11345	COG1136	(ABC) transporter
NXW12_RS11360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXW12_RS11365	COG1597	lipid kinase activity
NXW12_RS11370	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXW12_RS11375	COG0612	Peptidase, M16
NXW12_RS11390	COG0791	NLP P60 protein
NXW12_RS11405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXW12_RS11410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXW12_RS11420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXW12_RS11425	COG0543	2 iron, 2 sulfur cluster binding
NXW12_RS11430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXW12_RS11435	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXW12_RS11455	COG0297	glycogen (starch) synthase activity
NXW12_RS11485	COG0519	Catalyzes the synthesis of GMP from XMP
NXW12_RS11485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXW12_RS11490	COG1970	mechanosensitive ion channel activity
NXW12_RS11510	COG2131	deaminase
NXW12_RS11515	COG0793	Belongs to the peptidase S41A family
NXW12_RS11520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXW12_RS11545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXW12_RS11565	COG0673	inositol 2-dehydrogenase activity
NXW12_RS11570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXW12_RS11575	COG3250	beta-galactosidase activity
NXW12_RS11595	COG0101	tRNA pseudouridine synthase activity
NXW12_RS11605	COG2268	Band 7 protein
NXW12_RS11625	COG1702	phosphate starvation-inducible protein PhoH
NXW12_RS11630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXW12_RS11635	COG2226	methyltransferase
NXW12_RS11645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXW12_RS11660	COG1704	LemA family
NXW12_RS11675	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NXW12_RS11680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXW12_RS11685	COG0284	orotidine-5'-phosphate decarboxylase activity
NXW12_RS11690	COG1078	dGTPase activity
NXW12_RS11695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW12_RS11700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXW12_RS11700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXW12_RS11715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXW12_RS11735	COG1506	peptidase
NXW12_RS11735	COG0823	Involved in the tonB-independent uptake of proteins
NXW12_RS11740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXW12_RS11750	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXW12_RS11760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXW12_RS11790	COG0546	phosphoglycolate phosphatase activity
NXW12_RS11810	COG2205	protein histidine kinase activity
NXW12_RS11810	COG2205	protein histidine kinase activity
NXW12_RS11810	COG0745	RESPONSE REGULATOR receiver
NXW12_RS11810	COG3292	Two component regulator propeller
NXW12_RS11810	COG0745	RESPONSE REGULATOR receiver
NXW12_RS11810	COG3292	Two component regulator propeller
NXW12_RS11875	COG4771	TonB-dependent receptor
NXW12_RS11890	COG0702	epimerase
NXW12_RS11895	COG4771	TonB-dependent receptor
NXW12_RS11935	COG3401	FG-GAP repeat protein
NXW12_RS11960	COG1629	transport
NXW12_RS11965	COG2205	protein histidine kinase activity
NXW12_RS11965	COG3292	Two component regulator propeller
NXW12_RS11965	COG0745	RESPONSE REGULATOR receiver
NXW12_RS11995	COG3401	FG-GAP repeat protein
NXW12_RS12000	COG3250	beta-galactosidase activity
NXW12_RS12025	COG3254	rhamnose metabolic process
NXW12_RS12035	COG3401	FG-GAP repeat protein
NXW12_RS12045	COG2755	lipolytic protein G-D-S-L family
NXW12_RS12060	COG3401	FG-GAP repeat protein
NXW12_RS12080	COG4771	TonB-dependent receptor
NXW12_RS12100	COG4771	TonB-dependent receptor
NXW12_RS12105	COG0702	epimerase
NXW12_RS12140	COG2755	lipolytic protein G-D-S-L family
NXW12_RS12175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXW12_RS12180	COG3292	Two component regulator propeller
NXW12_RS12180	COG2205	protein histidine kinase activity
NXW12_RS12180	COG0745	RESPONSE REGULATOR receiver
NXW12_RS12185	COG1242	4 iron, 4 sulfur cluster binding
NXW12_RS12195	COG0363	glucosamine-6-phosphate deaminase activity
NXW12_RS12200	COG2755	lipolytic protein G-D-S-L family
NXW12_RS12200	COG0657	acetylesterase activity
NXW12_RS12205	COG0009	L-threonylcarbamoyladenylate synthase
NXW12_RS12215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW12_RS12220	COG0561	phosphatase activity
NXW12_RS12235	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXW12_RS12260	COG0702	epimerase
NXW12_RS12265	COG4771	TonB-dependent receptor
NXW12_RS12295	COG3279	Response regulator of the LytR AlgR family
NXW12_RS12305	COG1629	transport
NXW12_RS12305	COG4206	TonB-dependent receptor
NXW12_RS12310	COG0702	epimerase
NXW12_RS12340	COG2205	protein histidine kinase activity
NXW12_RS12340	COG0745	RESPONSE REGULATOR receiver
NXW12_RS12340	COG3292	Two component regulator propeller
NXW12_RS12345	COG2755	lipolytic protein G-D-S-L family
NXW12_RS12355	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS12360	COG3775	system Galactitol-specific IIC component
NXW12_RS12365	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXW12_RS12370	COG2271	Major facilitator Superfamily
NXW12_RS12380	COG0805	protein transport
NXW12_RS12385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXW12_RS12400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXW12_RS12405	COG0569	domain protein
NXW12_RS12410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXW12_RS12425	COG3537	Alpha-1,2-mannosidase
NXW12_RS12460	COG4771	TonB-dependent receptor
NXW12_RS12465	COG0702	epimerase
NXW12_RS12470	COG1629	transport
NXW12_RS12480	COG3250	beta-galactosidase activity
NXW12_RS12525	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW12_RS12530	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW12_RS12535	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW12_RS12535	COG0649	NAD binding
NXW12_RS12540	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXW12_RS12555	COG0713	ATP synthesis coupled electron transport
NXW12_RS12560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXW12_RS12565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW12_RS12575	COG0784	Response regulator, receiver
NXW12_RS12575	COG2198	Histidine kinase
NXW12_RS12575	COG5002	protein histidine kinase activity
NXW12_RS12595	COG2207	Transcriptional regulator
NXW12_RS12595	COG0662	Cupin 2, conserved barrel domain protein
NXW12_RS12600	COG0668	transmembrane transport
NXW12_RS12635	COG4974	Belongs to the 'phage' integrase family
NXW12_RS12660	COG1040	competence protein
NXW12_RS12700	COG0784	Response regulator, receiver
NXW12_RS12700	COG2205	protein histidine kinase activity
NXW12_RS12705	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS12710	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW12_RS12730	COG4771	TonB-dependent receptor
NXW12_RS12755	COG1475	DNA binding
NXW12_RS12945	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW12_RS12955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXW12_RS12960	COG2239	Acts as a magnesium transporter
NXW12_RS12965	COG1196	nuclear chromosome segregation
NXW12_RS13000	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS13060	COG4974	Belongs to the 'phage' integrase family
NXW12_RS13065	COG4974	Belongs to the 'phage' integrase family
NXW12_RS13070	COG4974	Belongs to the 'phage' integrase family
NXW12_RS13135	COG1629	transport
NXW12_RS13145	COG1192	Involved in chromosome partitioning
NXW12_RS13185	COG1120	ATPase activity
NXW12_RS13190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXW12_RS13250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXW12_RS13255	COG0575	Belongs to the CDS family
NXW12_RS13265	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW12_RS13270	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXW12_RS13275	COG1192	Involved in chromosome partitioning
NXW12_RS13280	COG1475	DNA binding
NXW12_RS13290	COG1388	LysM domain
NXW12_RS13290	COG0741	lytic transglycosylase activity
NXW12_RS13295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXW12_RS13305	COG0739	heme binding
NXW12_RS13380	COG0768	penicillin binding
NXW12_RS13395	COG0582	viral genome integration into host DNA
NXW12_RS13420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXW12_RS13440	COG3537	Alpha-1,2-mannosidase
NXW12_RS13445	COG3537	Alpha-1,2-mannosidase
NXW12_RS13470	COG1629	transport
NXW12_RS13470	COG4206	TonB-dependent receptor
NXW12_RS13515	COG0742	ribosomal rna small subunit methyltransferase
NXW12_RS13520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXW12_RS13535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXW12_RS13550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXW12_RS13560	COG0386	Belongs to the glutathione peroxidase family
NXW12_RS13575	COG3275	phosphorelay sensor kinase activity
NXW12_RS13580	COG3279	Response regulator of the LytR AlgR family
NXW12_RS13585	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS13590	COG3537	Alpha-1,2-mannosidase
NXW12_RS13600	COG3537	Alpha-1,2-mannosidase
NXW12_RS13605	COG3537	Alpha-1,2-mannosidase
NXW12_RS13615	COG4771	TonB-dependent receptor
NXW12_RS13630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXW12_RS13640	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXW12_RS13645	COG2333	competence protein COMEC
NXW12_RS13645	COG0658	competence protein
NXW12_RS13650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXW12_RS13655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXW12_RS13665	COG0009	L-threonylcarbamoyladenylate synthase
NXW12_RS13675	COG4771	TonB-dependent receptor
NXW12_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
NXW12_RS13695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW12_RS13700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW12_RS13725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW12_RS13730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW12_RS13745	COG0726	polysaccharide deacetylase
NXW12_RS13760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXW12_RS13765	COG1215	transferase activity, transferring glycosyl groups
NXW12_RS13830	COG0514	ATP-dependent DNA helicase (RecQ)
NXW12_RS13850	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXW12_RS13860	COG0358	DNA primase activity
NXW12_RS13865	COG0302	gtp cyclohydrolase
NXW12_RS13875	COG0149	triose-phosphate isomerase activity
NXW12_RS13890	COG0739	heme binding
NXW12_RS13895	COG0105	UTP biosynthetic process
NXW12_RS13905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXW12_RS13920	COG0848	biopolymer transport protein
NXW12_RS13925	COG0811	peptide transport
NXW12_RS13930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXW12_RS13935	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXW12_RS13945	COG0039	L-malate dehydrogenase activity
NXW12_RS13985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW12_RS13990	COG0489	protein tyrosine kinase activity
NXW12_RS13995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXW12_RS14005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXW12_RS14015	COG1570	exodeoxyribonuclease VII activity
NXW12_RS14025	COG0482	sulfurtransferase activity
NXW12_RS14040	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXW12_RS14045	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXW12_RS14050	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXW12_RS14065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXW12_RS14070	COG0052	Belongs to the universal ribosomal protein uS2 family
NXW12_RS14075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXW12_RS14080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXW12_RS14085	COG0702	epimerase
NXW12_RS14090	COG4771	TonB-dependent receptor
NXW12_RS14120	COG3292	Two component regulator propeller
NXW12_RS14120	COG2205	protein histidine kinase activity
NXW12_RS14120	COG0745	RESPONSE REGULATOR receiver
NXW12_RS14125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS14135	COG0017	Asparaginyl-tRNA synthetase
NXW12_RS14140	COG1187	pseudouridine synthase activity
NXW12_RS14160	COG0110	maltose O-acetyltransferase activity
NXW12_RS14165	COG3022	response to hydroperoxide
NXW12_RS14175	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXW12_RS14190	COG3547	Transposase (IS116 IS110 IS902 family)
NXW12_RS14200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXW12_RS14215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXW12_RS14230	COG0516	GMP reductase activity
NXW12_RS14230	COG0517	IMP dehydrogenase activity
NXW12_RS14255	COG0582	viral genome integration into host DNA
NXW12_RS14270	COG0514	ATP-dependent DNA helicase (RecQ)
NXW12_RS14275	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXW12_RS14280	COG0740	serine-type endopeptidase activity
NXW12_RS14285	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXW12_RS14290	COG0724	RNA recognition motif
NXW12_RS14295	COG1127	ABC transporter
NXW12_RS14300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXW12_RS14310	COG1160	GTP binding
NXW12_RS14315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXW12_RS14320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXW12_RS14385	COG2193	ferroxidase activity
NXW12_RS14390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXW12_RS14400	COG0470	DNA polymerase III
NXW12_RS14405	COG1774	PSP1 C-terminal conserved region
NXW12_RS14415	COG0772	Belongs to the SEDS family
NXW12_RS14440	COG0138	bifunctional purine biosynthesis protein purh
NXW12_RS14445	COG3590	peptidase
NXW12_RS14450	COG0488	(ABC) transporter
NXW12_RS14470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW12_RS14470	COG2205	protein histidine kinase activity
NXW12_RS14475	COG0534	Mate efflux family protein
NXW12_RS14480	COG0612	Peptidase, M16
NXW12_RS14485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXW12_RS14485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXW12_RS14490	COG2204	response regulator
NXW12_RS14495	COG3119	arylsulfatase activity
NXW12_RS14515	COG1629	transport
NXW12_RS14515	COG4206	TonB-dependent receptor
NXW12_RS14535	COG2205	protein histidine kinase activity
NXW12_RS14535	COG3292	Two component regulator propeller
NXW12_RS14535	COG0745	RESPONSE REGULATOR receiver
NXW12_RS14540	COG3537	Alpha-1,2-mannosidase
NXW12_RS14570	COG0564	pseudouridine synthase activity
NXW12_RS14595	COG3250	beta-galactosidase activity
NXW12_RS14600	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW12_RS14630	COG0702	epimerase
NXW12_RS14635	COG4771	TonB-dependent receptor
NXW12_RS14640	COG0745	RESPONSE REGULATOR receiver
NXW12_RS14640	COG2205	protein histidine kinase activity
NXW12_RS14640	COG3292	Two component regulator propeller
NXW12_RS14650	COG1454	alcohol dehydrogenase
NXW12_RS14655	COG0235	Class ii aldolase
NXW12_RS14665	COG4806	L-rhamnose isomerase
NXW12_RS14670	COG1070	Carbohydrate kinase
NXW12_RS14675	COG1438	arginine binding
NXW12_RS14685	COG0137	argininosuccinate synthase activity
NXW12_RS14690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXW12_RS14700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXW12_RS14710	COG1396	sequence-specific DNA binding
NXW12_RS14710	COG1917	Cupin 2, conserved barrel domain protein
NXW12_RS14715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXW12_RS14760	COG4771	TonB-dependent receptor
NXW12_RS14790	COG4206	TonB-dependent receptor
NXW12_RS14790	COG1629	transport
NXW12_RS14815	COG0165	Argininosuccinate lyase
NXW12_RS14825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXW12_RS14835	COG2890	protein-(glutamine-N5) methyltransferase activity
NXW12_RS14840	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW12_RS14840	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW12_RS14850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXW12_RS14855	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXW12_RS14870	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXW12_RS14880	COG0436	Aminotransferase
NXW12_RS14900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXW12_RS14905	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXW12_RS14930	COG0564	pseudouridine synthase activity
NXW12_RS14935	COG2815	serine threonine protein kinase
NXW12_RS14935	COG0515	serine threonine protein kinase
NXW12_RS14940	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXW12_RS14945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXW12_RS14955	COG1785	Belongs to the alkaline phosphatase family
NXW12_RS14965	COG0366	Alpha amylase catalytic
NXW12_RS14970	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS14975	COG1629	transport
NXW12_RS14975	COG4206	TonB-dependent receptor
NXW12_RS14980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS14995	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXW12_RS15010	COG3250	beta-galactosidase activity
NXW12_RS15045	COG4206	TonB-dependent receptor
NXW12_RS15045	COG1629	transport
NXW12_RS15050	COG2205	protein histidine kinase activity
NXW12_RS15050	COG3292	Two component regulator propeller
NXW12_RS15050	COG0745	RESPONSE REGULATOR receiver
NXW12_RS15055	COG2003	Belongs to the UPF0758 family
NXW12_RS15070	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXW12_RS15075	COG0280	phosphate acetyltransferase
NXW12_RS15080	COG1380	Effector of murein hydrolase LrgA
NXW12_RS15085	COG1346	cytolysis
NXW12_RS15155	COG4771	TonB-dependent receptor
NXW12_RS15165	COG0745	RESPONSE REGULATOR receiver
NXW12_RS15165	COG2205	protein histidine kinase activity
NXW12_RS15165	COG3292	Two component regulator propeller
NXW12_RS15185	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS15200	COG4977	sequence-specific DNA binding
NXW12_RS15215	COG4206	TonB-dependent receptor
NXW12_RS15215	COG1629	transport
NXW12_RS15225	COG1082	Xylose isomerase domain protein TIM barrel
NXW12_RS15245	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXW12_RS15250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXW12_RS15255	COG5002	protein histidine kinase activity
NXW12_RS15255	COG0784	Response regulator, receiver
NXW12_RS15260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXW12_RS15270	COG0733	neurotransmitter:sodium symporter activity
NXW12_RS15280	COG1136	(ABC) transporter
NXW12_RS15285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXW12_RS15290	COG0475	glutathione-regulated potassium exporter activity
NXW12_RS15290	COG0589	response to stress
NXW12_RS15295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXW12_RS15355	COG1216	Glycosyl transferase, family 2
NXW12_RS15355	COG0463	Glycosyl transferase, family 2
NXW12_RS15365	COG2211	Major facilitator Superfamily
NXW12_RS15375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXW12_RS15390	COG0745	RESPONSE REGULATOR receiver
NXW12_RS15390	COG3292	Two component regulator propeller
NXW12_RS15390	COG2205	protein histidine kinase activity
NXW12_RS15395	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS15400	COG2382	esterase
NXW12_RS15430	COG1629	transport
NXW12_RS15440	COG4771	TonB-dependent receptor
NXW12_RS15445	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS15450	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS15465	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS15470	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS15480	COG1063	alcohol dehydrogenase
NXW12_RS15485	COG0738	Major facilitator superfamily
NXW12_RS15500	COG1609	Transcriptional regulator
NXW12_RS15525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NXW12_RS15525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXW12_RS15545	COG0423	glycine-tRNA ligase activity
NXW12_RS15550	COG1373	ATPase (AAA superfamily
NXW12_RS15560	COG1609	Transcriptional regulator
NXW12_RS15560	COG2207	Transcriptional regulator
NXW12_RS15570	COG1629	transport
NXW12_RS15590	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS15600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXW12_RS15625	COG0673	inositol 2-dehydrogenase activity
NXW12_RS15635	COG0673	inositol 2-dehydrogenase activity
NXW12_RS15640	COG1595	DNA-templated transcription, initiation
NXW12_RS15660	COG3547	Transposase (IS116 IS110 IS902 family)
NXW12_RS15675	COG1629	transport
NXW12_RS15685	COG2271	Major facilitator Superfamily
NXW12_RS15715	COG4771	TonB-dependent receptor
NXW12_RS15720	COG0561	phosphatase activity
NXW12_RS15755	COG3591	Belongs to the peptidase S1B family
NXW12_RS15755	COG1864	DNA RNA non-specific endonuclease
NXW12_RS15815	COG1022	Amp-dependent synthetase and ligase
NXW12_RS15820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXW12_RS15830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW12_RS15870	COG2017	converts alpha-aldose to the beta-anomer
NXW12_RS15880	COG3537	Alpha-1,2-mannosidase
NXW12_RS15910	COG0561	phosphatase activity
NXW12_RS15915	COG4771	TonB-dependent receptor
NXW12_RS15945	COG3119	arylsulfatase activity
NXW12_RS15950	COG3661	Belongs to the glycosyl hydrolase 67 family
NXW12_RS15975	COG4771	TonB-dependent receptor
NXW12_RS15985	COG4771	TonB-dependent receptor
NXW12_RS15990	COG1629	transport
NXW12_RS15990	COG4206	TonB-dependent receptor
NXW12_RS16015	COG3119	arylsulfatase activity
NXW12_RS16025	COG3119	arylsulfatase activity
NXW12_RS16045	COG3119	arylsulfatase activity
NXW12_RS16055	COG0702	epimerase
NXW12_RS16095	COG0702	epimerase
NXW12_RS16100	COG4771	TonB-dependent receptor
NXW12_RS16115	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS16130	COG1629	transport
NXW12_RS16130	COG4206	TonB-dependent receptor
NXW12_RS16140	COG4771	TonB-dependent receptor
NXW12_RS16155	COG3119	arylsulfatase activity
NXW12_RS16165	COG3292	Two component regulator propeller
NXW12_RS16165	COG2205	protein histidine kinase activity
NXW12_RS16165	COG0745	RESPONSE REGULATOR receiver
NXW12_RS16170	COG4942	peptidase
NXW12_RS16185	COG0756	dUTP diphosphatase activity
NXW12_RS16210	COG0702	epimerase
NXW12_RS16215	COG1629	transport
NXW12_RS16225	COG3940	Belongs to the glycosyl hydrolase 43 family
NXW12_RS16230	COG2205	protein histidine kinase activity
NXW12_RS16230	COG3292	Two component regulator propeller
NXW12_RS16230	COG0745	RESPONSE REGULATOR receiver
NXW12_RS16235	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXW12_RS16260	COG2001	Belongs to the MraZ family
NXW12_RS16265	COG0275	rRNA processing
NXW12_RS16280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXW12_RS16285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXW12_RS16290	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXW12_RS16295	COG0772	Belongs to the SEDS family
NXW12_RS16300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXW12_RS16305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXW12_RS16320	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXW12_RS16365	COG1381	Involved in DNA repair and RecF pathway recombination
NXW12_RS16415	COG0268	Binds directly to 16S ribosomal RNA
NXW12_RS16420	COG0187	DNA topoisomerase II activity
NXW12_RS16435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXW12_RS16455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXW12_RS16460	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXW12_RS16465	COG0745	RESPONSE REGULATOR receiver
NXW12_RS16465	COG2205	protein histidine kinase activity
NXW12_RS16465	COG3292	Two component regulator propeller
NXW12_RS16465	COG3292	Two component regulator propeller
NXW12_RS16465	COG3292	Two component regulator propeller
NXW12_RS16465	COG0745	RESPONSE REGULATOR receiver
NXW12_RS16465	COG2205	protein histidine kinase activity
NXW12_RS16465	COG2205	protein histidine kinase activity
NXW12_RS16465	COG0745	RESPONSE REGULATOR receiver
NXW12_RS16480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXW12_RS16485	COG0719	Fe-S assembly protein
NXW12_RS16490	COG0396	ATPase activity
NXW12_RS16495	COG0719	Fe-S assembly protein
NXW12_RS16505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXW12_RS16510	COG0195	Participates in both transcription termination and antitermination
NXW12_RS16515	COG0779	Required for maturation of 30S ribosomal subunits
NXW12_RS16540	COG1595	DNA-templated transcription, initiation
NXW12_RS16545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NXW12_RS16550	COG1166	arginine decarboxylase activity
NXW12_RS16560	COG0326	Molecular chaperone. Has ATPase activity
NXW12_RS16570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXW12_RS16580	COG3341	Caulimovirus viroplasmin
NXW12_RS16580	COG0328	RNA-DNA hybrid ribonuclease activity
NXW12_RS16610	COG1132	(ABC) transporter
NXW12_RS16625	COG5433	transposase activity
NXW12_RS16630	COG5433	transposase activity
NXW12_RS16670	COG1442	glycosyl transferase family 8
NXW12_RS16670	COG1216	Glycosyl transferase, family 2
NXW12_RS16675	COG1216	Glycosyl transferase, family 2
NXW12_RS16690	COG1216	Glycosyl transferase, family 2
NXW12_RS16690	COG1442	glycosyl transferase family 8
NXW12_RS16705	COG4750	Nucleotidyl transferase
NXW12_RS16710	COG3475	LICD family
NXW12_RS16715	COG0438	transferase activity, transferring glycosyl groups
NXW12_RS16750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXW12_RS16760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW12_RS16765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW12_RS16770	COG0571	ribonuclease III activity
NXW12_RS16775	COG0205	6-phosphofructokinase activity
NXW12_RS16790	COG0482	sulfurtransferase activity
NXW12_RS16795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXW12_RS16815	COG0561	phosphatase activity
NXW12_RS16820	COG0215	cysteine-tRNA ligase activity
NXW12_RS16825	COG5492	domain, Protein
NXW12_RS16830	COG3119	arylsulfatase activity
NXW12_RS16835	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS16845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NXW12_RS16850	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS16855	COG0702	epimerase
NXW12_RS16860	COG1629	transport
NXW12_RS16915	COG0702	epimerase
NXW12_RS16930	COG4771	TonB-dependent receptor
NXW12_RS16935	COG3250	beta-galactosidase activity
NXW12_RS16940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW12_RS16950	COG1538	Outer membrane efflux protein
NXW12_RS16955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW12_RS16965	COG1609	Transcriptional regulator
NXW12_RS16975	COG3250	beta-galactosidase activity
NXW12_RS16980	COG1940	carbohydrate kinase activity
NXW12_RS16995	COG0738	Major facilitator superfamily
NXW12_RS17015	COG4771	TonB-dependent receptor
NXW12_RS17025	COG1629	transport
NXW12_RS17030	COG0702	epimerase
NXW12_RS17045	COG3292	Two component regulator propeller
NXW12_RS17045	COG2205	protein histidine kinase activity
NXW12_RS17045	COG0745	RESPONSE REGULATOR receiver
NXW12_RS17045	COG2205	protein histidine kinase activity
NXW12_RS17045	COG3292	Two component regulator propeller
NXW12_RS17045	COG0745	RESPONSE REGULATOR receiver
NXW12_RS17050	COG3119	arylsulfatase activity
NXW12_RS17055	COG4771	TonB-dependent receptor
NXW12_RS17060	COG0702	epimerase
NXW12_RS17070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXW12_RS17095	COG5492	domain, Protein
NXW12_RS17180	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXW12_RS17190	COG0681	Belongs to the peptidase S26 family
NXW12_RS17230	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS17245	COG0702	epimerase
NXW12_RS17250	COG4771	TonB-dependent receptor
NXW12_RS17260	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NXW12_RS17275	COG5433	transposase activity
NXW12_RS17280	COG5433	transposase activity
NXW12_RS17295	COG4771	TonB-dependent receptor
NXW12_RS17300	COG0702	epimerase
NXW12_RS17320	COG0584	glycerophosphoryl diester phosphodiesterase
NXW12_RS17330	COG0612	Peptidase, M16
NXW12_RS17345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW12_RS17380	COG0702	epimerase
NXW12_RS17385	COG1629	transport
NXW12_RS17395	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS17405	COG0513	Belongs to the DEAD box helicase family
NXW12_RS17410	COG3591	Belongs to the peptidase S1B family
NXW12_RS17430	COG2255	four-way junction helicase activity
NXW12_RS17435	COG2715	membrane protein required for spore maturation
NXW12_RS17440	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXW12_RS17505	COG0445	tRNA wobble uridine modification
NXW12_RS17510	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXW12_RS17515	COG0322	excinuclease ABC activity
NXW12_RS17520	COG1490	D-aminoacyl-tRNA deacylase activity
NXW12_RS17525	COG1694	Mazg nucleotide pyrophosphohydrolase
NXW12_RS17530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXW12_RS17545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXW12_RS17545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXW12_RS17555	COG3279	Response regulator of the LytR AlgR family
NXW12_RS17565	COG1045	serine acetyltransferase
NXW12_RS17570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXW12_RS17570	COG0116	Belongs to the methyltransferase superfamily
NXW12_RS17580	COG1506	peptidase
NXW12_RS17580	COG0823	Involved in the tonB-independent uptake of proteins
NXW12_RS17595	COG1238	metal cluster binding
NXW12_RS17610	COG1121	(ABC) transporter
NXW12_RS17620	COG0726	polysaccharide deacetylase
NXW12_RS17655	COG1028	Short-chain dehydrogenase reductase Sdr
NXW12_RS17660	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXW12_RS17665	COG1629	transport
NXW12_RS17665	COG4206	TonB-dependent receptor
NXW12_RS17675	COG0784	Response regulator, receiver
NXW12_RS17675	COG2205	protein histidine kinase activity
NXW12_RS17695	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXW12_RS17700	COG0594	ribonuclease P activity
NXW12_RS17715	COG1611	Belongs to the LOG family
NXW12_RS17755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXW12_RS17765	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXW12_RS17770	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXW12_RS17775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXW12_RS17780	COG1968	undecaprenyl-diphosphatase activity
NXW12_RS17790	COG2177	Part of the ABC transporter FtsEX involved in
NXW12_RS17830	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS17855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW12_RS17865	COG0427	acetyl-CoA hydrolase
NXW12_RS17870	COG2027	D-alanyl-D-alanine carboxypeptidase
NXW12_RS17900	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW12_RS17915	COG4771	TonB-dependent receptor
NXW12_RS17930	COG0745	RESPONSE REGULATOR receiver
NXW12_RS17930	COG2205	protein histidine kinase activity
NXW12_RS17930	COG3292	Two component regulator propeller
NXW12_RS17935	COG1592	Rubrerythrin
NXW12_RS17940	COG0659	secondary active sulfate transmembrane transporter activity
NXW12_RS17955	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS17985	COG3292	Two component regulator propeller
NXW12_RS17985	COG2205	protein histidine kinase activity
NXW12_RS17985	COG0745	RESPONSE REGULATOR receiver
NXW12_RS17985	COG3292	Two component regulator propeller
NXW12_RS17985	COG0745	RESPONSE REGULATOR receiver
NXW12_RS17985	COG2205	protein histidine kinase activity
NXW12_RS18035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS18055	COG1629	transport
NXW12_RS18080	COG0784	Response regulator, receiver
NXW12_RS18080	COG2205	protein histidine kinase activity
NXW12_RS18080	COG2198	Histidine kinase
NXW12_RS18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW12_RS18090	COG0731	radical SAM domain protein
NXW12_RS18090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXW12_RS18120	COG4206	TonB-dependent receptor
NXW12_RS18120	COG1629	transport
NXW12_RS18150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXW12_RS18155	COG1360	Flagellar Motor Protein
NXW12_RS18160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXW12_RS18165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXW12_RS18170	COG0495	leucyl-tRNA aminoacylation
NXW12_RS18175	COG3250	beta-galactosidase activity
NXW12_RS18190	COG0697	spore germination
NXW12_RS18195	COG1785	Belongs to the alkaline phosphatase family
NXW12_RS18210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXW12_RS18220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXW12_RS18225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXW12_RS18230	COG0012	GTP binding
NXW12_RS18255	COG1629	transport
NXW12_RS18255	COG4206	TonB-dependent receptor
NXW12_RS18275	COG2814	Major facilitator Superfamily
NXW12_RS18285	COG3119	arylsulfatase activity
NXW12_RS18320	COG4206	TonB-dependent receptor
NXW12_RS18320	COG1629	transport
NXW12_RS18335	COG3292	Two component regulator propeller
NXW12_RS18335	COG2205	protein histidine kinase activity
NXW12_RS18335	COG0745	RESPONSE REGULATOR receiver
NXW12_RS18380	COG4771	TonB-dependent receptor
NXW12_RS18385	COG0702	epimerase
NXW12_RS18410	COG1917	Cupin 2, conserved barrel domain protein
NXW12_RS18415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXW12_RS18420	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS18435	COG1629	transport
NXW12_RS18435	COG4206	TonB-dependent receptor
NXW12_RS18445	COG5002	protein histidine kinase activity
NXW12_RS18455	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS18465	COG0557	exoribonuclease II activity
NXW12_RS18525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXW12_RS18530	COG0826	peptidase U32
NXW12_RS18540	COG0758	DNA mediated transformation
NXW12_RS18600	COG1609	Transcriptional regulator
NXW12_RS18600	COG2207	Transcriptional regulator
NXW12_RS18645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXW12_RS18650	COG1053	succinate dehydrogenase
NXW12_RS18675	COG4206	TonB-dependent receptor
NXW12_RS18675	COG1629	transport
NXW12_RS18680	COG0702	epimerase
NXW12_RS18705	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS18710	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS18715	COG4206	TonB-dependent receptor
NXW12_RS18715	COG1629	transport
NXW12_RS18735	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXW12_RS18740	COG3292	Two component regulator propeller
NXW12_RS18740	COG2205	protein histidine kinase activity
NXW12_RS18740	COG0745	RESPONSE REGULATOR receiver
NXW12_RS18745	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW12_RS18750	COG3250	beta-galactosidase activity
NXW12_RS18755	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS18760	COG0793	Belongs to the peptidase S41A family
NXW12_RS18760	COG3409	Peptidoglycan-binding domain 1 protein
NXW12_RS18765	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXW12_RS18790	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW12_RS18815	COG4771	TonB-dependent receptor
NXW12_RS18820	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW12_RS18840	COG4771	TonB-dependent receptor
NXW12_RS18915	COG0561	phosphatase activity
NXW12_RS18975	COG1196	nuclear chromosome segregation
NXW12_RS19050	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW12_RS19055	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW12_RS19060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXW12_RS19095	COG0438	transferase activity, transferring glycosyl groups
NXW12_RS19110	COG3475	LICD family
NXW12_RS19125	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW12_RS19125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW12_RS19140	COG0673	inositol 2-dehydrogenase activity
NXW12_RS19150	COG0673	inositol 2-dehydrogenase activity
NXW12_RS19170	COG0745	RESPONSE REGULATOR receiver
NXW12_RS19170	COG2205	protein histidine kinase activity
NXW12_RS19170	COG3292	Two component regulator propeller
NXW12_RS19190	COG4771	TonB-dependent receptor
NXW12_RS19210	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW12_RS19215	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW12_RS19225	COG4771	TonB-dependent receptor
NXW12_RS19230	COG0702	epimerase
NXW12_RS19240	COG2205	protein histidine kinase activity
NXW12_RS19245	COG0606	chelatase, subunit chli
NXW12_RS19260	COG4974	Belongs to the 'phage' integrase family
NXW12_RS19280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXW12_RS19285	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXW12_RS19300	COG4771	TonB-dependent receptor
NXW12_RS19340	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW12_RS19345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW12_RS19350	COG3345	alpha-galactosidase
NXW12_RS19355	COG3458	cephalosporin-C deacetylase activity
NXW12_RS19360	COG3250	beta-galactosidase activity
NXW12_RS19375	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXW12_RS19380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXW12_RS19380	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXW12_RS19435	COG3723	Recombinational DNA repair protein, rece pathway
NXW12_RS19580	COG1690	Belongs to the RtcB family
NXW12_RS19760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXW12_RS19765	COG0339	signal peptide processing
NXW12_RS19780	COG0705	Rhomboid family
NXW12_RS19790	COG0018	arginyl-trna synthetase
NXW12_RS19810	COG0745	RESPONSE REGULATOR receiver
NXW12_RS19810	COG2205	protein histidine kinase activity
NXW12_RS19810	COG3292	Two component regulator propeller
NXW12_RS19840	COG4771	TonB-dependent receptor
NXW12_RS19845	COG0561	phosphatase activity
NXW12_RS19875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NXW12_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS19920	COG3634	alkyl hydroperoxide reductase activity
NXW12_RS19930	COG2205	protein histidine kinase activity
NXW12_RS19930	COG0745	RESPONSE REGULATOR receiver
NXW12_RS19930	COG3292	Two component regulator propeller
NXW12_RS19935	COG4771	TonB-dependent receptor
NXW12_RS19970	COG2382	esterase
NXW12_RS19970	COG3693	PFAM glycoside hydrolase, family 10
NXW12_RS20000	COG1629	transport
NXW12_RS20000	COG4206	TonB-dependent receptor
NXW12_RS20005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW12_RS20010	COG1609	Transcriptional regulator
NXW12_RS20020	COG1629	transport
NXW12_RS20040	COG1929	Belongs to the glycerate kinase type-1 family
NXW12_RS20045	COG2610	gluconate transmembrane transporter activity
NXW12_RS20090	COG4771	TonB-dependent receptor
NXW12_RS20115	COG0457	Tetratricopeptide repeat
NXW12_RS20120	COG1595	DNA-templated transcription, initiation
NXW12_RS20135	COG1040	competence protein
NXW12_RS20150	COG1609	Transcriptional regulator
NXW12_RS20155	COG4771	TonB-dependent receptor
NXW12_RS20160	COG0702	epimerase
NXW12_RS20210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW12_RS20215	COG0793	Belongs to the peptidase S41A family
NXW12_RS20220	COG2205	protein histidine kinase activity
NXW12_RS20220	COG0784	Response regulator, receiver
NXW12_RS20220	COG5002	protein histidine kinase activity
NXW12_RS20225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXW12_RS20260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXW12_RS20265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXW12_RS20280	COG2059	Chromate
NXW12_RS20295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXW12_RS20300	COG1396	sequence-specific DNA binding
NXW12_RS20305	COG0318	PFAM AMP-dependent synthetase and ligase
NXW12_RS20310	COG0662	Cupin 2, conserved barrel domain protein
NXW12_RS20310	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXW12_RS20335	COG0501	Belongs to the peptidase M48B family
NXW12_RS20370	COG2096	Adenosyltransferase
NXW12_RS20415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NXW12_RS20440	COG4974	Belongs to the 'phage' integrase family
NXW12_RS20475	COG0252	asparaginase activity
NXW12_RS20480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXW12_RS20485	COG1027	Aspartate ammonia-lyase
NXW12_RS20490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW12_RS20510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXW12_RS20520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXW12_RS20530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXW12_RS20540	COG3118	belongs to the thioredoxin family
NXW12_RS20550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXW12_RS20555	COG0006	proline dipeptidase activity
NXW12_RS20560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXW12_RS20565	COG4974	Belongs to the 'phage' integrase family
NXW12_RS20605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXW12_RS20615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXW12_RS20620	COG0081	regulation of translation
NXW12_RS20625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXW12_RS20630	COG0222	ribosome binding
NXW12_RS20635	COG0085	RNA polymerase activity
NXW12_RS20640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXW12_RS20650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXW12_RS20655	COG0049	tRNA binding
NXW12_RS20660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXW12_RS20665	COG0051	transcription antitermination factor activity, RNA binding
NXW12_RS20670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXW12_RS20675	COG0088	Forms part of the polypeptide exit tunnel
NXW12_RS20680	COG0089	rRNA binding
NXW12_RS20685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXW12_RS20690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXW12_RS20695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXW12_RS20700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXW12_RS20705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXW12_RS20710	COG0255	Belongs to the universal ribosomal protein uL29 family
NXW12_RS20715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXW12_RS20720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXW12_RS20725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXW12_RS20730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXW12_RS20735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXW12_RS20740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXW12_RS20745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXW12_RS20750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXW12_RS20755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXW12_RS20760	COG1841	ribosomal large subunit assembly
NXW12_RS20765	COG0200	Binds to the 23S rRNA
NXW12_RS20780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXW12_RS20785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXW12_RS20790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXW12_RS20795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXW12_RS20800	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXW12_RS20805	COG0202	RNA polymerase activity
NXW12_RS20810	COG0203	ribosomal protein L17
NXW12_RS20825	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXW12_RS20835	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXW12_RS20845	COG1228	amidohydrolase
NXW12_RS20855	COG2986	histidine ammonia-lyase
NXW12_RS20860	COG1309	transcriptional regulator
NXW12_RS20895	COG1696	Membrane protein involved in D-alanine export
NXW12_RS20900	COG0667	Aldo Keto reductase
NXW12_RS20970	COG1131	(ABC) transporter
NXW12_RS20990	COG3345	alpha-galactosidase
NXW12_RS21025	COG2066	Belongs to the glutaminase family
NXW12_RS21030	COG0076	glutamate decarboxylase activity
NXW12_RS21050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXW12_RS21060	COG1185	polyribonucleotide nucleotidyltransferase activity
NXW12_RS21080	COG3537	Alpha-1,2-mannosidase
NXW12_RS21085	COG3426	butyrate kinase activity
NXW12_RS21090	COG0280	phosphate acetyltransferase
NXW12_RS21100	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXW12_RS21105	COG2234	aminopeptidase activity
NXW12_RS21110	COG2166	iron-sulfur cluster assembly
NXW12_RS21115	COG1266	CAAX protease self-immunity
NXW12_RS21120	COG0196	riboflavin kinase activity
NXW12_RS21125	COG1011	Hydrolase
NXW12_RS21140	COG1773	rubredoxin
NXW12_RS21150	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXW12_RS21165	COG3458	cephalosporin-C deacetylase activity
NXW12_RS21175	COG0006	proline dipeptidase activity
NXW12_RS21190	COG0509	glycine decarboxylation via glycine cleavage system
NXW12_RS21195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXW12_RS21200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXW12_RS21210	COG2217	Heavy metal translocating P-type atpase
NXW12_RS21220	COG0039	L-malate dehydrogenase activity
NXW12_RS21225	COG2996	Protein conserved in bacteria
NXW12_RS21245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXW12_RS21255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXW12_RS21255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXW12_RS21270	COG1136	(ABC) transporter
NXW12_RS21270	COG0577	efflux transmembrane transporter activity
NXW12_RS21275	COG0577	efflux transmembrane transporter activity
NXW12_RS21275	COG1136	(ABC) transporter
NXW12_RS21280	COG1136	(ABC) transporter
NXW12_RS21295	COG0335	large ribosomal subunit rRNA binding
NXW12_RS21300	COG0737	Belongs to the 5'-nucleotidase family
NXW12_RS21305	COG0737	Belongs to the 5'-nucleotidase family
NXW12_RS21310	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW12_RS21330	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXW12_RS21335	COG2204	response regulator
NXW12_RS21340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXW12_RS21450	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS21465	COG3973	AAA domain
NXW12_RS21485	COG0724	RNA recognition motif
NXW12_RS21495	COG0513	Belongs to the DEAD box helicase family
NXW12_RS21515	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXW12_RS21520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXW12_RS21525	COG1663	tetraacyldisaccharide 4'-kinase activity
NXW12_RS21530	COG0616	signal peptide processing
NXW12_RS21555	COG4771	TonB-dependent receptor
NXW12_RS21560	COG0702	epimerase
NXW12_RS21585	COG3292	Two component regulator propeller
NXW12_RS21585	COG2205	protein histidine kinase activity
NXW12_RS21585	COG0745	RESPONSE REGULATOR receiver
NXW12_RS21585	COG3292	Two component regulator propeller
NXW12_RS21585	COG2205	protein histidine kinase activity
NXW12_RS21585	COG0745	RESPONSE REGULATOR receiver
NXW12_RS21590	COG0471	metal ion transport
NXW12_RS21605	COG4771	TonB-dependent receptor
NXW12_RS21635	COG4948	Mandelate Racemase Muconate Lactonizing
NXW12_RS21685	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXW12_RS21690	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NXW12_RS21695	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXW12_RS21705	COG2205	protein histidine kinase activity
NXW12_RS21710	COG5002	protein histidine kinase activity
NXW12_RS21725	COG1131	(ABC) transporter
NXW12_RS21780	COG4771	TonB-dependent receptor
NXW12_RS21835	COG0582	viral genome integration into host DNA
NXW12_RS21865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXW12_RS21880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXW12_RS21885	COG0826	peptidase U32
NXW12_RS21900	COG4771	TonB-dependent receptor
NXW12_RS21910	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXW12_RS21915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXW12_RS21920	COG0252	asparaginase activity
NXW12_RS21925	COG0527	aspartate kinase activity
NXW12_RS21925	COG0460	homoserine dehydrogenase
NXW12_RS21930	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXW12_RS21935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXW12_RS21955	COG0668	transmembrane transport
NXW12_RS21970	COG1522	sequence-specific DNA binding
NXW12_RS21990	COG0534	Mate efflux family protein
NXW12_RS22005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXW12_RS22010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXW12_RS22020	COG2207	Transcriptional regulator
NXW12_RS22045	COG0475	glutathione-regulated potassium exporter activity
NXW12_RS22045	COG0589	response to stress
NXW12_RS22060	COG2076	Multidrug Resistance protein
NXW12_RS22090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXW12_RS22125	COG4771	TonB-dependent receptor
NXW12_RS22135	COG1396	sequence-specific DNA binding
NXW12_RS22140	COG4413	Urea transporter
NXW12_RS22145	COG0010	Belongs to the arginase family
NXW12_RS22150	COG0058	SHG alpha-glucan phosphorylase activity
NXW12_RS22165	COG0205	6-phosphofructokinase activity
NXW12_RS22170	COG1595	DNA-templated transcription, initiation
NXW12_RS22180	COG0588	phosphoglycerate mutase activity
NXW12_RS22185	COG1830	Aldolase
NXW12_RS22280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW12_RS22280	COG0551	DNA topoisomerase type I activity
NXW12_RS22350	COG3344	reverse transcriptase
NXW12_RS22515	COG4974	Belongs to the 'phage' integrase family
NXW12_RS22530	COG1435	thymidine kinase activity
NXW12_RS22540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXW12_RS22555	COG2095	MarC family integral membrane protein
NXW12_RS22570	COG1629	transport
NXW12_RS22575	COG4974	Belongs to the 'phage' integrase family
NXW12_RS22590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXW12_RS22605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXW12_RS22605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXW12_RS22620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXW12_RS22630	COG1162	GTPase activity
NXW12_RS22635	COG0233	cytoplasmic translational termination
NXW12_RS22645	COG2205	protein histidine kinase activity
NXW12_RS22645	COG3292	Two component regulator propeller
NXW12_RS22645	COG0745	RESPONSE REGULATOR receiver
NXW12_RS22790	COG0740	serine-type endopeptidase activity
NXW12_RS22875	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW12_RS22880	COG1629	transport
NXW12_RS22880	COG4206	TonB-dependent receptor
NXW12_RS22885	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS22895	COG3250	beta-galactosidase activity
NXW12_RS22910	COG0528	UMP kinase activity
NXW12_RS22915	COG0534	Mate efflux family protein
NXW12_RS22940	COG0792	nuclease activity
NXW12_RS22960	COG1183	phosphatidylcholine synthase activity
NXW12_RS22965	COG0688	phosphatidylethanolamine metabolic process
NXW12_RS22980	COG2814	Major facilitator Superfamily
NXW12_RS23000	COG4771	TonB-dependent receptor
NXW12_RS23005	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW12_RS23020	COG0726	polysaccharide deacetylase
NXW12_RS23030	COG3118	belongs to the thioredoxin family
NXW12_RS23065	COG0714	Associated with various cellular activities
NXW12_RS23080	COG0802	atpase or kinase
NXW12_RS23085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXW12_RS23095	COG2234	aminopeptidase activity
NXW12_RS23110	COG1629	transport
NXW12_RS23110	COG4206	TonB-dependent receptor
NXW12_RS23125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXW12_RS23130	COG1373	ATPase (AAA superfamily
NXW12_RS23165	COG2431	L-lysine efflux transmembrane transporter activity
NXW12_RS23205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXW12_RS23235	COG0360	Binds together with S18 to 16S ribosomal RNA
NXW12_RS23240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXW12_RS23245	COG0359	binds to the 23S rRNA
NXW12_RS23280	COG1022	Amp-dependent synthetase and ligase
NXW12_RS23285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW12_RS23295	COG1216	Glycosyl transferase, family 2
NXW12_RS23315	COG1640	4-alpha-glucanotransferase
NXW12_RS23325	COG0778	Nitroreductase
NXW12_RS23340	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS23370	COG0358	DNA primase activity
NXW12_RS23380	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXW12_RS23405	COG2315	Protein conserved in bacteria
NXW12_RS23415	COG3876	Protein conserved in bacteria
NXW12_RS23430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXW12_RS23435	COG2502	aspartate--ammonia ligase
NXW12_RS23455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXW12_RS23475	COG0166	Belongs to the GPI family
NXW12_RS23480	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXW12_RS23485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXW12_RS23490	COG0534	Mate efflux family protein
NXW12_RS23495	COG2207	Transcriptional regulator
NXW12_RS23495	COG1609	Transcriptional regulator
NXW12_RS23505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXW12_RS23535	COG2188	Transcriptional regulator
NXW12_RS23555	COG4771	TonB-dependent receptor
NXW12_RS23620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXW12_RS23655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NXW12_RS23675	COG0569	domain protein
NXW12_RS23675	COG2985	domain, Protein
NXW12_RS23680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW12_RS23685	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW12_RS23685	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW12_RS23710	COG1629	transport
NXW12_RS23710	COG4206	TonB-dependent receptor
NXW12_RS23755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXW12_RS23785	COG0129	dihydroxy-acid dehydratase activity
NXW12_RS23790	COG0028	Belongs to the TPP enzyme family
NXW12_RS23805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXW12_RS23820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXW12_RS23830	COG0372	Belongs to the citrate synthase family
NXW12_RS23865	COG0205	6-phosphofructokinase activity
NXW12_RS23870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXW12_RS23875	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXW12_RS23895	COG0084	hydrolase, TatD family'
NXW12_RS23905	COG0811	peptide transport
NXW12_RS23935	COG1522	sequence-specific DNA binding
NXW12_RS23945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXW12_RS23950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXW12_RS23960	COG1595	DNA-templated transcription, initiation
NXW12_RS24000	COG0488	(ABC) transporter
NXW12_RS24005	COG2204	response regulator
NXW12_RS24015	COG1629	transport
NXW12_RS24020	COG1629	transport
NXW12_RS24020	COG4206	TonB-dependent receptor
NXW12_RS24025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXW12_RS24030	COG1272	protein, Hemolysin III
NXW12_RS24045	COG0673	inositol 2-dehydrogenase activity
NXW12_RS24050	COG0632	four-way junction helicase activity
NXW12_RS24070	COG0617	tRNA 3'-terminal CCA addition
NXW12_RS24080	COG3119	arylsulfatase activity
NXW12_RS24085	COG3119	arylsulfatase activity
NXW12_RS24100	COG1505	serine-type exopeptidase activity
NXW12_RS24130	COG3550	peptidyl-serine autophosphorylation
NXW12_RS24150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXW12_RS24180	COG0561	phosphatase activity
NXW12_RS24195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS24240	COG1629	transport
NXW12_RS24260	COG1538	Outer membrane efflux protein
NXW12_RS24295	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS24320	COG1629	transport
NXW12_RS24320	COG4206	TonB-dependent receptor
NXW12_RS24325	COG4206	TonB-dependent receptor
NXW12_RS24325	COG1629	transport
NXW12_RS24380	COG1328	CTP reductase activity
NXW12_RS24390	COG2814	Major facilitator Superfamily
NXW12_RS24400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXW12_RS24415	COG0750	zinc metalloprotease
NXW12_RS24420	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXW12_RS24430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXW12_RS24435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXW12_RS24455	COG0194	GDP metabolic process
NXW12_RS24460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXW12_RS24470	COG1408	metallophosphoesterase
NXW12_RS24475	COG1575	Belongs to the MenA family. Type 1 subfamily
NXW12_RS24480	COG1088	dTDP-glucose 4,6-dehydratase activity
NXW12_RS24485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXW12_RS24495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXW12_RS24520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXW12_RS24525	COG2873	o-acetylhomoserine
NXW12_RS24535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW12_RS24545	COG0439	Biotin carboxylase
NXW12_RS24550	COG3118	belongs to the thioredoxin family
NXW12_RS24555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXW12_RS24575	COG1028	Short-chain dehydrogenase reductase Sdr
NXW12_RS24655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXW12_RS24660	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXW12_RS24665	COG0066	3-isopropylmalate dehydratase activity
NXW12_RS24675	COG0473	3-isopropylmalate dehydrogenase activity
NXW12_RS24680	COG0671	phosphoesterase, PA-phosphatase related
NXW12_RS24685	COG1368	sulfuric ester hydrolase activity
NXW12_RS24700	COG0514	ATP-dependent DNA helicase (RecQ)
NXW12_RS24725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXW12_RS24740	COG0124	histidyl-tRNA synthetase
NXW12_RS24745	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXW12_RS24755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXW12_RS24785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXW12_RS24790	COG0459	protein refolding
NXW12_RS24820	COG0028	Belongs to the TPP enzyme family
NXW12_RS24840	COG2194	sulfuric ester hydrolase activity
NXW12_RS24845	COG0484	heat shock protein binding
NXW12_RS24855	COG1956	GAF domain-containing protein
NXW12_RS24875	COG1960	acyl-CoA dehydrogenase activity
NXW12_RS24880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXW12_RS24905	COG4772	TonB-dependent receptor
NXW12_RS24935	COG3279	Response regulator of the LytR AlgR family
NXW12_RS24985	COG1621	beta-fructofuranosidase activity
NXW12_RS24995	COG4771	TonB-dependent receptor
NXW12_RS25015	COG1621	beta-fructofuranosidase activity
NXW12_RS25030	COG4206	TonB-dependent receptor
NXW12_RS25030	COG1629	transport
NXW12_RS25035	COG2205	protein histidine kinase activity
NXW12_RS25035	COG0745	RESPONSE REGULATOR receiver
NXW12_RS25035	COG3292	Two component regulator propeller
NXW12_RS25045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXW12_RS25055	COG4176	ABC-type proline glycine betaine transport system permease component
NXW12_RS25060	COG2113	Glycine betaine
NXW12_RS25225	COG0622	Phosphoesterase
NXW12_RS25250	COG4771	TonB-dependent receptor
NXW12_RS25275	COG2375	cellular response to nickel ion
NXW12_RS25275	COG1132	(ABC) transporter
NXW12_RS25285	COG0428	transporter
NXW12_RS25340	COG3015	lipoprotein NlpE involved in copper resistance
NXW12_RS25465	COG4372	Transposase
NXW12_RS25470	COG2433	Pfam Transposase IS66
NXW12_RS25535	COG0702	epimerase
NXW12_RS25540	COG1629	transport
NXW12_RS25545	COG3292	Two component regulator propeller
NXW12_RS25545	COG0745	RESPONSE REGULATOR receiver
NXW12_RS25545	COG2205	protein histidine kinase activity
NXW12_RS25580	COG2095	MarC family integral membrane protein
NXW12_RS25590	COG1830	Aldolase
NXW12_RS25595	COG0588	phosphoglycerate mutase activity
NXW12_RS25615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW12_RS25615	COG4651	solute:proton antiporter activity
NXW12_RS25625	COG0010	Belongs to the arginase family
NXW12_RS25690	COG0739	heme binding
NXW12_RS25735	COG4974	Belongs to the 'phage' integrase family
NXW12_RS25740	COG1649	PFAM Uncharacterised BCR, COG1649
NXW12_RS25745	COG1966	Carbon starvation protein
NXW12_RS25770	COG1649	PFAM Uncharacterised BCR, COG1649
NXW12_RS25795	COG1280	lysine exporter protein (LysE YggA)
NXW12_RS25810	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXW12_RS25835	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXW12_RS25920	COG1373	ATPase (AAA superfamily
NXW12_RS25925	COG0254	rRNA binding
NXW12_RS25930	COG0191	fructose-bisphosphate aldolase activity
NXW12_RS25935	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXW12_RS25940	COG0511	ligase activity, forming carbon-carbon bonds
NXW12_RS25950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW12_RS25965	COG1629	transport
NXW12_RS25975	COG0288	reversible hydration of carbon dioxide
NXW12_RS25985	COG0778	Nitroreductase
NXW12_RS26005	COG0424	maF-like protein
NXW12_RS26015	COG2311	Membrane
NXW12_RS26030	COG0126	phosphoglycerate kinase activity
NXW12_RS26035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXW12_RS26040	COG2814	Major facilitator Superfamily
NXW12_RS26045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXW12_RS26085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXW12_RS26090	COG1523	belongs to the glycosyl hydrolase 13 family
NXW12_RS26100	COG1629	transport
NXW12_RS26100	COG4206	TonB-dependent receptor
NXW12_RS26105	COG0561	phosphatase activity
NXW12_RS26125	COG2211	Major facilitator Superfamily
NXW12_RS26140	COG3661	Belongs to the glycosyl hydrolase 67 family
NXW12_RS26145	COG1119	ATPase activity
NXW12_RS26165	COG1629	transport
NXW12_RS26165	COG4206	TonB-dependent receptor
NXW12_RS26180	COG0588	phosphoglycerate mutase activity
NXW12_RS26185	COG1830	Aldolase
NXW12_RS26190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXW12_RS26205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXW12_RS26225	COG4206	TonB-dependent receptor
NXW12_RS26225	COG1629	transport
NXW12_RS26240	COG3119	arylsulfatase activity
NXW12_RS26245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW12_RS26250	COG3250	beta-galactosidase activity
NXW12_RS26260	COG0668	transmembrane transport
NXW12_RS26270	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW12_RS26295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXW12_RS26305	COG1983	PspC domain protein
NXW12_RS26320	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXW12_RS26325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXW12_RS26330	COG0534	Mate efflux family protein
NXW12_RS26340	COG2205	protein histidine kinase activity
NXW12_RS26340	COG2202	Pas domain
NXW12_RS26345	COG3119	arylsulfatase activity
NXW12_RS26360	COG0037	tRNA processing
NXW12_RS26365	COG1918	ferrous iron import across plasma membrane
NXW12_RS26365	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXW12_RS26400	COG1396	sequence-specific DNA binding
NXW12_RS26405	COG3177	Filamentation induced by cAMP protein fic
NXW12_RS26480	COG0305	Participates in initiation and elongation during chromosome replication
NXW12_RS26555	COG0346	lactoylglutathione lyase activity
NXW12_RS26570	COG0259	pyridoxamine-phosphate oxidase activity
NXW12_RS26575	COG1741	Belongs to the pirin family
NXW12_RS26580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXW12_RS26595	COG1595	DNA-templated transcription, initiation
NXW12_RS26605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXW12_RS26610	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXW12_RS26630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXW12_RS26675	COG0686	Belongs to the AlaDH PNT family
NXW12_RS26690	COG4206	TonB-dependent receptor
NXW12_RS26690	COG1629	transport
NXW12_RS26710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXW12_RS26725	COG0488	(ABC) transporter
NXW12_RS26730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW12_RS26735	COG3059	membrane
NXW12_RS26745	COG0295	cytidine deaminase activity
NXW12_RS26750	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXW12_RS26755	COG1252	NADH dehydrogenase
NXW12_RS26765	COG1136	(ABC) transporter
NXW12_RS26785	COG0577	efflux transmembrane transporter activity
NXW12_RS26805	COG2204	response regulator
NXW12_RS26810	COG4191	Histidine kinase
NXW12_RS26825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXW12_RS26835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXW12_RS26850	COG1979	alcohol dehydrogenase
NXW12_RS26890	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW12_RS26945	COG1530	ribonuclease E activity
NXW12_RS26960	COG0629	single-stranded DNA binding
NXW12_RS26985	COG3033	Beta-eliminating lyase
NXW12_RS27015	COG0745	RESPONSE REGULATOR receiver
NXW12_RS27030	COG0488	(ABC) transporter