locus-tag	class	description
NXV93_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXV93_RS00010	COG0778	Nitroreductase
NXV93_RS00020	COG1640	4-alpha-glucanotransferase
NXV93_RS00040	COG1216	Glycosyl transferase, family 2
NXV93_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV93_RS00055	COG1022	Amp-dependent synthetase and ligase
NXV93_RS00090	COG0359	binds to the 23S rRNA
NXV93_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXV93_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
NXV93_RS00125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXV93_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXV93_RS00170	COG2431	L-lysine efflux transmembrane transporter activity
NXV93_RS00210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXV93_RS00225	COG4206	TonB-dependent receptor
NXV93_RS00225	COG1629	transport
NXV93_RS00240	COG2234	aminopeptidase activity
NXV93_RS00255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXV93_RS00260	COG0802	atpase or kinase
NXV93_RS00285	COG0714	Associated with various cellular activities
NXV93_RS00320	COG3118	belongs to the thioredoxin family
NXV93_RS00335	COG0726	polysaccharide deacetylase
NXV93_RS00350	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS00355	COG4206	TonB-dependent receptor
NXV93_RS00355	COG1629	transport
NXV93_RS00360	COG1629	transport
NXV93_RS00360	COG4206	TonB-dependent receptor
NXV93_RS00375	COG0457	Tetratricopeptide repeat
NXV93_RS00380	COG2814	Major facilitator Superfamily
NXV93_RS00395	COG0688	phosphatidylethanolamine metabolic process
NXV93_RS00400	COG1183	phosphatidylcholine synthase activity
NXV93_RS00420	COG0792	nuclease activity
NXV93_RS00435	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV93_RS00445	COG0534	Mate efflux family protein
NXV93_RS00450	COG0528	UMP kinase activity
NXV93_RS00465	COG3250	beta-galactosidase activity
NXV93_RS00475	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS00480	COG4206	TonB-dependent receptor
NXV93_RS00480	COG1629	transport
NXV93_RS00485	COG3292	Two component regulator propeller
NXV93_RS00485	COG2205	protein histidine kinase activity
NXV93_RS00485	COG0745	RESPONSE REGULATOR receiver
NXV93_RS00495	COG0233	cytoplasmic translational termination
NXV93_RS00500	COG1162	GTPase activity
NXV93_RS00515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXV93_RS00530	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXV93_RS00530	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXV93_RS00565	COG4974	Belongs to the 'phage' integrase family
NXV93_RS00570	COG4771	TonB-dependent receptor
NXV93_RS00580	COG1629	transport
NXV93_RS00595	COG2095	MarC family integral membrane protein
NXV93_RS00610	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXV93_RS00620	COG1435	thymidine kinase activity
NXV93_RS00625	COG0628	permease
NXV93_RS00640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXV93_RS00660	COG3328	transposase activity
NXV93_RS00670	COG1396	sequence-specific DNA binding
NXV93_RS00680	COG4771	TonB-dependent receptor
NXV93_RS00740	COG2076	Multidrug Resistance protein
NXV93_RS00755	COG0589	response to stress
NXV93_RS00755	COG0475	glutathione-regulated potassium exporter activity
NXV93_RS00780	COG2207	Transcriptional regulator
NXV93_RS00790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXV93_RS00810	COG0534	Mate efflux family protein
NXV93_RS00830	COG1522	sequence-specific DNA binding
NXV93_RS00845	COG0668	transmembrane transport
NXV93_RS00865	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXV93_RS00870	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXV93_RS00875	COG0460	homoserine dehydrogenase
NXV93_RS00875	COG0527	aspartate kinase activity
NXV93_RS00880	COG0252	asparaginase activity
NXV93_RS00885	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXV93_RS00890	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXV93_RS00900	COG4771	TonB-dependent receptor
NXV93_RS00920	COG0826	peptidase U32
NXV93_RS00925	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXV93_RS00940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXV93_RS00960	COG0519	Catalyzes the synthesis of GMP from XMP
NXV93_RS00965	COG5002	protein histidine kinase activity
NXV93_RS00970	COG2205	protein histidine kinase activity
NXV93_RS00980	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXV93_RS00985	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NXV93_RS00990	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXV93_RS01000	COG3387	PFAM Glycoside hydrolase 15-related
NXV93_RS01045	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS01080	COG4771	TonB-dependent receptor
NXV93_RS01115	COG0702	epimerase
NXV93_RS01120	COG4771	TonB-dependent receptor
NXV93_RS01145	COG0616	signal peptide processing
NXV93_RS01150	COG1663	tetraacyldisaccharide 4'-kinase activity
NXV93_RS01155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXV93_RS01160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXV93_RS01180	COG0513	Belongs to the DEAD box helicase family
NXV93_RS01185	COG2070	2-Nitropropane dioxygenase
NXV93_RS01190	COG0724	RNA recognition motif
NXV93_RS01210	COG3973	AAA domain
NXV93_RS01220	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS01245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXV93_RS01290	COG2885	chlorophyll binding
NXV93_RS01345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXV93_RS01405	COG2204	response regulator
NXV93_RS01410	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXV93_RS01430	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS01435	COG0737	Belongs to the 5'-nucleotidase family
NXV93_RS01440	COG0737	Belongs to the 5'-nucleotidase family
NXV93_RS01445	COG0335	large ribosomal subunit rRNA binding
NXV93_RS01455	COG1136	(ABC) transporter
NXV93_RS01460	COG1136	(ABC) transporter
NXV93_RS01460	COG0577	efflux transmembrane transporter activity
NXV93_RS01465	COG1136	(ABC) transporter
NXV93_RS01465	COG0577	efflux transmembrane transporter activity
NXV93_RS01480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXV93_RS01480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXV93_RS01490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXV93_RS01510	COG2996	Protein conserved in bacteria
NXV93_RS01515	COG0039	L-malate dehydrogenase activity
NXV93_RS01535	COG1595	DNA-templated transcription, initiation
NXV93_RS01545	COG1629	transport
NXV93_RS01590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXV93_RS01595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXV93_RS01600	COG0509	glycine decarboxylation via glycine cleavage system
NXV93_RS01615	COG0006	proline dipeptidase activity
NXV93_RS01635	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXV93_RS01645	COG1773	rubredoxin
NXV93_RS01655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXV93_RS01660	COG1011	Hydrolase
NXV93_RS01665	COG0196	riboflavin kinase activity
NXV93_RS01670	COG1266	CAAX protease self-immunity
NXV93_RS01680	COG2234	aminopeptidase activity
NXV93_RS01685	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXV93_RS01695	COG0280	phosphate acetyltransferase
NXV93_RS01700	COG3426	butyrate kinase activity
NXV93_RS01705	COG3537	Alpha-1,2-mannosidase
NXV93_RS01725	COG1185	polyribonucleotide nucleotidyltransferase activity
NXV93_RS01735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXV93_RS01760	COG2066	Belongs to the glutaminase family
NXV93_RS01770	COG0531	amino acid
NXV93_RS01775	COG2205	protein histidine kinase activity
NXV93_RS01775	COG3437	response regulator, receiver
NXV93_RS01775	COG3850	Histidine kinase
NXV93_RS01775	COG4999	Histidine kinase
NXV93_RS01790	COG3345	alpha-galactosidase
NXV93_RS01810	COG1131	(ABC) transporter
NXV93_RS01885	COG0667	Aldo Keto reductase
NXV93_RS01890	COG1696	Membrane protein involved in D-alanine export
NXV93_RS01925	COG1309	transcriptional regulator
NXV93_RS01930	COG2986	histidine ammonia-lyase
NXV93_RS01940	COG1228	amidohydrolase
NXV93_RS01960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXV93_RS01975	COG0203	ribosomal protein L17
NXV93_RS01980	COG0202	RNA polymerase activity
NXV93_RS01985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXV93_RS01990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXV93_RS01995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXV93_RS02000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXV93_RS02005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXV93_RS02020	COG0200	Binds to the 23S rRNA
NXV93_RS02025	COG1841	ribosomal large subunit assembly
NXV93_RS02030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXV93_RS02035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXV93_RS02040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXV93_RS02045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXV93_RS02050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXV93_RS02055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXV93_RS02060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXV93_RS02065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXV93_RS02070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXV93_RS02075	COG0255	Belongs to the universal ribosomal protein uL29 family
NXV93_RS02080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXV93_RS02085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXV93_RS02090	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXV93_RS02095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXV93_RS02100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXV93_RS02105	COG0089	rRNA binding
NXV93_RS02110	COG0088	Forms part of the polypeptide exit tunnel
NXV93_RS02115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXV93_RS02120	COG0051	transcription antitermination factor activity, RNA binding
NXV93_RS02125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXV93_RS02130	COG0049	tRNA binding
NXV93_RS02135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXV93_RS02145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXV93_RS02150	COG0085	RNA polymerase activity
NXV93_RS02155	COG0222	ribosome binding
NXV93_RS02160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXV93_RS02165	COG0081	regulation of translation
NXV93_RS02170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXV93_RS02180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXV93_RS02190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXV93_RS02220	COG4974	Belongs to the 'phage' integrase family
NXV93_RS02225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXV93_RS02230	COG0006	proline dipeptidase activity
NXV93_RS02235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXV93_RS02245	COG3118	belongs to the thioredoxin family
NXV93_RS02255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXV93_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXV93_RS02275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXV93_RS02325	COG4974	Belongs to the 'phage' integrase family
NXV93_RS02405	COG0739	heme binding
NXV93_RS02465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV93_RS02465	COG2198	Histidine kinase
NXV93_RS02465	COG2205	protein histidine kinase activity
NXV93_RS02465	COG0784	Response regulator, receiver
NXV93_RS02475	COG0010	Belongs to the arginase family
NXV93_RS02480	COG0058	SHG alpha-glucan phosphorylase activity
NXV93_RS02485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXV93_RS02485	COG4651	solute:proton antiporter activity
NXV93_RS02505	COG0588	phosphoglycerate mutase activity
NXV93_RS02510	COG1830	Aldolase
NXV93_RS02520	COG2095	MarC family integral membrane protein
NXV93_RS02545	COG0745	RESPONSE REGULATOR receiver
NXV93_RS02545	COG2205	protein histidine kinase activity
NXV93_RS02545	COG3292	Two component regulator propeller
NXV93_RS02550	COG1629	transport
NXV93_RS02555	COG0702	epimerase
NXV93_RS02625	COG2433	Pfam Transposase IS66
NXV93_RS02630	COG4372	Transposase
NXV93_RS02745	COG3015	lipoprotein NlpE involved in copper resistance
NXV93_RS02790	COG0428	transporter
NXV93_RS02800	COG1132	(ABC) transporter
NXV93_RS02800	COG2375	cellular response to nickel ion
NXV93_RS02825	COG4771	TonB-dependent receptor
NXV93_RS02850	COG0622	Phosphoesterase
NXV93_RS02990	COG1027	Aspartate ammonia-lyase
NXV93_RS02995	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXV93_RS03000	COG0252	asparaginase activity
NXV93_RS03015	COG2096	Adenosyltransferase
NXV93_RS03050	COG0501	Belongs to the peptidase M48B family
NXV93_RS03070	COG3328	transposase activity
NXV93_RS03095	COG2972	Histidine kinase
NXV93_RS03110	COG0662	Cupin 2, conserved barrel domain protein
NXV93_RS03110	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXV93_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
NXV93_RS03120	COG1396	sequence-specific DNA binding
NXV93_RS03130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXV93_RS03150	COG2059	Chromate
NXV93_RS03165	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXV93_RS03170	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXV93_RS03210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXV93_RS03220	COG0793	Belongs to the peptidase S41A family
NXV93_RS03225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV93_RS03240	COG1040	competence protein
NXV93_RS03310	COG1629	transport
NXV93_RS03315	COG1609	Transcriptional regulator
NXV93_RS03320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV93_RS03325	COG1629	transport
NXV93_RS03325	COG4206	TonB-dependent receptor
NXV93_RS03355	COG2382	esterase
NXV93_RS03355	COG3693	PFAM glycoside hydrolase, family 10
NXV93_RS03390	COG4771	TonB-dependent receptor
NXV93_RS03395	COG0745	RESPONSE REGULATOR receiver
NXV93_RS03395	COG2205	protein histidine kinase activity
NXV93_RS03395	COG3292	Two component regulator propeller
NXV93_RS03415	COG2816	NAD+ diphosphatase activity
NXV93_RS03460	COG0018	arginyl-trna synthetase
NXV93_RS03470	COG0705	Rhomboid family
NXV93_RS03485	COG0339	signal peptide processing
NXV93_RS03490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXV93_RS03500	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXV93_RS03500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXV93_RS03505	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXV93_RS03520	COG3250	beta-galactosidase activity
NXV93_RS03525	COG3458	cephalosporin-C deacetylase activity
NXV93_RS03535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXV93_RS03540	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS03580	COG4771	TonB-dependent receptor
NXV93_RS03595	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXV93_RS03600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXV93_RS03620	COG4974	Belongs to the 'phage' integrase family
NXV93_RS03670	COG0582	viral genome integration into host DNA
NXV93_RS03760	COG2205	protein histidine kinase activity
NXV93_RS03785	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS03790	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS03805	COG1216	Glycosyl transferase, family 2
NXV93_RS03830	COG1216	Glycosyl transferase, family 2
NXV93_RS03840	COG1216	Glycosyl transferase, family 2
NXV93_RS03840	COG1442	glycosyl transferase family 8
NXV93_RS03845	COG1442	glycosyl transferase family 8
NXV93_RS03845	COG1216	Glycosyl transferase, family 2
NXV93_RS03900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS03905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXV93_RS03920	COG4974	Belongs to the 'phage' integrase family
NXV93_RS03925	COG4974	Belongs to the 'phage' integrase family
NXV93_RS03990	COG1629	transport
NXV93_RS04000	COG1192	Involved in chromosome partitioning
NXV93_RS04025	COG1120	ATPase activity
NXV93_RS04030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXV93_RS04090	COG0702	epimerase
NXV93_RS04105	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS04110	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS04130	COG4771	TonB-dependent receptor
NXV93_RS04155	COG2205	protein histidine kinase activity
NXV93_RS04155	COG0745	RESPONSE REGULATOR receiver
NXV93_RS04155	COG3292	Two component regulator propeller
NXV93_RS04175	COG0673	inositol 2-dehydrogenase activity
NXV93_RS04185	COG0673	inositol 2-dehydrogenase activity
NXV93_RS04190	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS04205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV93_RS04205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV93_RS04220	COG3475	LICD family
NXV93_RS04235	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS04265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXV93_RS04270	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV93_RS04275	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV93_RS04330	COG0732	type I restriction modification DNA specificity domain
NXV93_RS04335	COG4974	Belongs to the 'phage' integrase family
NXV93_RS04405	COG0561	phosphatase activity
NXV93_RS04470	COG4771	TonB-dependent receptor
NXV93_RS04480	COG0702	epimerase
NXV93_RS04490	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV93_RS04495	COG3250	beta-galactosidase activity
NXV93_RS04500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV93_RS04510	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXV93_RS04515	COG2211	Major facilitator Superfamily
NXV93_RS04520	COG3408	Glycogen debranching enzyme
NXV93_RS04545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXV93_RS04550	COG0793	Belongs to the peptidase S41A family
NXV93_RS04550	COG3409	Peptidoglycan-binding domain 1 protein
NXV93_RS04555	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS04560	COG3250	beta-galactosidase activity
NXV93_RS04565	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS04570	COG3292	Two component regulator propeller
NXV93_RS04570	COG0745	RESPONSE REGULATOR receiver
NXV93_RS04570	COG2205	protein histidine kinase activity
NXV93_RS04575	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV93_RS04580	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS04605	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS04660	COG0702	epimerase
NXV93_RS04665	COG4771	TonB-dependent receptor
NXV93_RS04670	COG3292	Two component regulator propeller
NXV93_RS04670	COG0745	RESPONSE REGULATOR receiver
NXV93_RS04670	COG2205	protein histidine kinase activity
NXV93_RS04695	COG0702	epimerase
NXV93_RS04700	COG4206	TonB-dependent receptor
NXV93_RS04700	COG1629	transport
NXV93_RS04705	COG3292	Two component regulator propeller
NXV93_RS04705	COG2205	protein histidine kinase activity
NXV93_RS04705	COG0745	RESPONSE REGULATOR receiver
NXV93_RS04725	COG1053	succinate dehydrogenase
NXV93_RS04730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXV93_RS04860	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NXV93_RS04880	COG0758	DNA mediated transformation
NXV93_RS04890	COG0826	peptidase U32
NXV93_RS04895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXV93_RS04955	COG0557	exoribonuclease II activity
NXV93_RS04980	COG1373	ATPase (AAA superfamily
NXV93_RS05000	COG0702	epimerase
NXV93_RS05005	COG4206	TonB-dependent receptor
NXV93_RS05005	COG1629	transport
NXV93_RS05020	COG5002	protein histidine kinase activity
NXV93_RS05030	COG4206	TonB-dependent receptor
NXV93_RS05030	COG1629	transport
NXV93_RS05045	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS05050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXV93_RS05055	COG1917	Cupin 2, conserved barrel domain protein
NXV93_RS05095	COG3254	rhamnose metabolic process
NXV93_RS05100	COG0702	epimerase
NXV93_RS05105	COG0561	phosphatase activity
NXV93_RS05110	COG4771	TonB-dependent receptor
NXV93_RS05120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS05125	COG3292	Two component regulator propeller
NXV93_RS05125	COG2205	protein histidine kinase activity
NXV93_RS05125	COG0745	RESPONSE REGULATOR receiver
NXV93_RS05130	COG0745	RESPONSE REGULATOR receiver
NXV93_RS05130	COG3292	Two component regulator propeller
NXV93_RS05130	COG2205	protein histidine kinase activity
NXV93_RS05150	COG0702	epimerase
NXV93_RS05155	COG4771	TonB-dependent receptor
NXV93_RS05190	COG3119	arylsulfatase activity
NXV93_RS05190	COG3408	Glycogen debranching enzyme
NXV93_RS05235	COG4206	TonB-dependent receptor
NXV93_RS05235	COG1629	transport
NXV93_RS05260	COG3119	arylsulfatase activity
NXV93_RS05270	COG2814	Major facilitator Superfamily
NXV93_RS05285	COG4206	TonB-dependent receptor
NXV93_RS05285	COG1629	transport
NXV93_RS05310	COG0012	GTP binding
NXV93_RS05315	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXV93_RS05320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXV93_RS05325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXV93_RS05330	COG3537	Alpha-1,2-mannosidase
NXV93_RS05340	COG1785	Belongs to the alkaline phosphatase family
NXV93_RS05345	COG0697	spore germination
NXV93_RS05360	COG3250	beta-galactosidase activity
NXV93_RS05370	COG4974	Belongs to the 'phage' integrase family
NXV93_RS05620	COG0517	IMP dehydrogenase activity
NXV93_RS05625	COG4974	Belongs to the 'phage' integrase family
NXV93_RS05645	COG0551	DNA topoisomerase type I activity
NXV93_RS05645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV93_RS05660	COG4804	nuclease activity
NXV93_RS05690	COG0495	leucyl-tRNA aminoacylation
NXV93_RS05695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXV93_RS05700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXV93_RS05705	COG1360	Flagellar Motor Protein
NXV93_RS05715	COG1629	transport
NXV93_RS05715	COG4206	TonB-dependent receptor
NXV93_RS05720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS05745	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS05750	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXV93_RS05770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXV93_RS05770	COG0731	radical SAM domain protein
NXV93_RS05800	COG0702	epimerase
NXV93_RS05805	COG1629	transport
NXV93_RS05820	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS05840	COG1629	transport
NXV93_RS05845	COG0745	RESPONSE REGULATOR receiver
NXV93_RS05845	COG3292	Two component regulator propeller
NXV93_RS05845	COG2205	protein histidine kinase activity
NXV93_RS05895	COG4206	TonB-dependent receptor
NXV93_RS05895	COG1629	transport
NXV93_RS05910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS05915	COG0659	secondary active sulfate transmembrane transporter activity
NXV93_RS05920	COG1592	Rubrerythrin
NXV93_RS05925	COG0745	RESPONSE REGULATOR receiver
NXV93_RS05925	COG3292	Two component regulator propeller
NXV93_RS05925	COG2205	protein histidine kinase activity
NXV93_RS05940	COG4771	TonB-dependent receptor
NXV93_RS05955	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXV93_RS05985	COG2027	D-alanyl-D-alanine carboxypeptidase
NXV93_RS05990	COG0427	acetyl-CoA hydrolase
NXV93_RS06000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV93_RS06025	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS06055	COG2177	Part of the ABC transporter FtsEX involved in
NXV93_RS06065	COG1968	undecaprenyl-diphosphatase activity
NXV93_RS06070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXV93_RS06075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXV93_RS06080	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXV93_RS06090	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXV93_RS06125	COG1611	Belongs to the LOG family
NXV93_RS06145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXV93_RS06155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXV93_RS06180	COG1629	transport
NXV93_RS06180	COG4206	TonB-dependent receptor
NXV93_RS06185	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXV93_RS06190	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS06230	COG0726	polysaccharide deacetylase
NXV93_RS06240	COG1121	(ABC) transporter
NXV93_RS06255	COG1238	metal cluster binding
NXV93_RS06270	COG1506	peptidase
NXV93_RS06270	COG0823	Involved in the tonB-independent uptake of proteins
NXV93_RS06280	COG0116	Belongs to the methyltransferase superfamily
NXV93_RS06280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXV93_RS06285	COG1045	serine acetyltransferase
NXV93_RS06295	COG3279	Response regulator of the LytR AlgR family
NXV93_RS06305	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXV93_RS06305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXV93_RS06310	COG0142	geranyltranstransferase activity
NXV93_RS06320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXV93_RS06325	COG1694	Mazg nucleotide pyrophosphohydrolase
NXV93_RS06330	COG1490	D-aminoacyl-tRNA deacylase activity
NXV93_RS06335	COG0322	excinuclease ABC activity
NXV93_RS06340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXV93_RS06345	COG0445	tRNA wobble uridine modification
NXV93_RS06385	COG4771	TonB-dependent receptor
NXV93_RS06450	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXV93_RS06460	COG2255	four-way junction helicase activity
NXV93_RS06480	COG3591	Belongs to the peptidase S1B family
NXV93_RS06530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV93_RS06545	COG0612	Peptidase, M16
NXV93_RS06565	COG0584	glycerophosphoryl diester phosphodiesterase
NXV93_RS06585	COG1629	transport
NXV93_RS06620	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NXV93_RS06630	COG4771	TonB-dependent receptor
NXV93_RS06635	COG0702	epimerase
NXV93_RS06650	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS06690	COG0681	Belongs to the peptidase S26 family
NXV93_RS06700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXV93_RS06730	COG1215	transferase activity, transferring glycosyl groups
NXV93_RS06750	COG5492	domain, Protein
NXV93_RS06775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXV93_RS06785	COG0702	epimerase
NXV93_RS06790	COG4771	TonB-dependent receptor
NXV93_RS06795	COG3119	arylsulfatase activity
NXV93_RS06800	COG3292	Two component regulator propeller
NXV93_RS06800	COG0745	RESPONSE REGULATOR receiver
NXV93_RS06800	COG3292	Two component regulator propeller
NXV93_RS06800	COG2205	protein histidine kinase activity
NXV93_RS06800	COG0745	RESPONSE REGULATOR receiver
NXV93_RS06800	COG2205	protein histidine kinase activity
NXV93_RS06820	COG0702	epimerase
NXV93_RS06825	COG1629	transport
NXV93_RS06840	COG4771	TonB-dependent receptor
NXV93_RS06860	COG0738	Major facilitator superfamily
NXV93_RS06875	COG1940	carbohydrate kinase activity
NXV93_RS06880	COG3250	beta-galactosidase activity
NXV93_RS06890	COG1609	Transcriptional regulator
NXV93_RS06900	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV93_RS06905	COG1538	Outer membrane efflux protein
NXV93_RS06920	COG3250	beta-galactosidase activity
NXV93_RS06925	COG4771	TonB-dependent receptor
NXV93_RS06940	COG0702	epimerase
NXV93_RS06975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS06980	COG3119	arylsulfatase activity
NXV93_RS06985	COG5492	domain, Protein
NXV93_RS06990	COG0215	cysteine-tRNA ligase activity
NXV93_RS06995	COG0561	phosphatase activity
NXV93_RS07020	COG0482	sulfurtransferase activity
NXV93_RS07030	COG0205	6-phosphofructokinase activity
NXV93_RS07035	COG0571	ribonuclease III activity
NXV93_RS07040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXV93_RS07045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXV93_RS07050	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NXV93_RS07055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXV93_RS07090	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS07095	COG3475	LICD family
NXV93_RS07100	COG4750	Nucleotidyl transferase
NXV93_RS07105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXV93_RS07115	COG1216	Glycosyl transferase, family 2
NXV93_RS07115	COG1442	glycosyl transferase family 8
NXV93_RS07135	COG1216	Glycosyl transferase, family 2
NXV93_RS07135	COG1442	glycosyl transferase family 8
NXV93_RS07180	COG1132	(ABC) transporter
NXV93_RS07190	COG0463	Glycosyl transferase, family 2
NXV93_RS07200	COG1368	sulfuric ester hydrolase activity
NXV93_RS07210	COG0328	RNA-DNA hybrid ribonuclease activity
NXV93_RS07210	COG3341	Caulimovirus viroplasmin
NXV93_RS07220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXV93_RS07230	COG0326	Molecular chaperone. Has ATPase activity
NXV93_RS07240	COG1166	arginine decarboxylase activity
NXV93_RS07250	COG1595	DNA-templated transcription, initiation
NXV93_RS07275	COG0779	Required for maturation of 30S ribosomal subunits
NXV93_RS07280	COG0195	Participates in both transcription termination and antitermination
NXV93_RS07285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXV93_RS07295	COG0719	Fe-S assembly protein
NXV93_RS07300	COG0396	ATPase activity
NXV93_RS07305	COG0719	Fe-S assembly protein
NXV93_RS07325	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07325	COG3292	Two component regulator propeller
NXV93_RS07325	COG2205	protein histidine kinase activity
NXV93_RS07325	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07325	COG2205	protein histidine kinase activity
NXV93_RS07325	COG3292	Two component regulator propeller
NXV93_RS07330	COG3292	Two component regulator propeller
NXV93_RS07330	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07330	COG2205	protein histidine kinase activity
NXV93_RS07335	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXV93_RS07340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXV93_RS07360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXV93_RS07375	COG0187	DNA topoisomerase II activity
NXV93_RS07380	COG0268	Binds directly to 16S ribosomal RNA
NXV93_RS07430	COG1381	Involved in DNA repair and RecF pathway recombination
NXV93_RS07500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXV93_RS07505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXV93_RS07510	COG0772	Belongs to the SEDS family
NXV93_RS07515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXV93_RS07520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXV93_RS07525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXV93_RS07540	COG0275	rRNA processing
NXV93_RS07545	COG2001	Belongs to the MraZ family
NXV93_RS07565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXV93_RS07570	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07570	COG2205	protein histidine kinase activity
NXV93_RS07570	COG3292	Two component regulator propeller
NXV93_RS07570	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07570	COG2205	protein histidine kinase activity
NXV93_RS07570	COG3292	Two component regulator propeller
NXV93_RS07575	COG3940	Belongs to the glycosyl hydrolase 43 family
NXV93_RS07615	COG0756	dUTP diphosphatase activity
NXV93_RS07630	COG4942	peptidase
NXV93_RS07635	COG2205	protein histidine kinase activity
NXV93_RS07635	COG0745	RESPONSE REGULATOR receiver
NXV93_RS07635	COG3292	Two component regulator propeller
NXV93_RS07645	COG3119	arylsulfatase activity
NXV93_RS07665	COG4771	TonB-dependent receptor
NXV93_RS07675	COG4206	TonB-dependent receptor
NXV93_RS07675	COG1629	transport
NXV93_RS07695	COG0702	epimerase
NXV93_RS07700	COG1629	transport
NXV93_RS07730	COG4771	TonB-dependent receptor
NXV93_RS07735	COG0702	epimerase
NXV93_RS07745	COG3119	arylsulfatase activity
NXV93_RS07780	COG0582	viral genome integration into host DNA
NXV93_RS07795	COG0768	penicillin binding
NXV93_RS07800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXV93_RS07840	COG3119	arylsulfatase activity
NXV93_RS07850	COG3119	arylsulfatase activity
NXV93_RS07860	COG3119	arylsulfatase activity
NXV93_RS07890	COG4771	TonB-dependent receptor
NXV93_RS07895	COG0561	phosphatase activity
NXV93_RS07925	COG3537	Alpha-1,2-mannosidase
NXV93_RS07935	COG2017	converts alpha-aldose to the beta-anomer
NXV93_RS08060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV93_RS08065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXV93_RS08070	COG1022	Amp-dependent synthetase and ligase
NXV93_RS08075	COG0612	Peptidase, M16
NXV93_RS08095	COG2954	triphosphatase activity
NXV93_RS08105	COG1373	ATPase (AAA superfamily
NXV93_RS08135	COG1864	DNA RNA non-specific endonuclease
NXV93_RS08135	COG3591	Belongs to the peptidase S1B family
NXV93_RS08165	COG0561	phosphatase activity
NXV93_RS08170	COG4771	TonB-dependent receptor
NXV93_RS08200	COG0673	inositol 2-dehydrogenase activity
NXV93_RS08210	COG0673	inositol 2-dehydrogenase activity
NXV93_RS08235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXV93_RS08245	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS08265	COG1629	transport
NXV93_RS08275	COG1609	Transcriptional regulator
NXV93_RS08275	COG2207	Transcriptional regulator
NXV93_RS08285	COG1373	ATPase (AAA superfamily
NXV93_RS08290	COG0423	glycine-tRNA ligase activity
NXV93_RS08300	COG1609	Transcriptional regulator
NXV93_RS08315	COG0738	Major facilitator superfamily
NXV93_RS08320	COG1063	alcohol dehydrogenase
NXV93_RS08330	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS08335	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS08340	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS08355	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS08360	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS08365	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS08370	COG4771	TonB-dependent receptor
NXV93_RS08380	COG4771	TonB-dependent receptor
NXV93_RS08400	COG5520	Belongs to the glycosyl hydrolase 30 family
NXV93_RS08415	COG2382	esterase
NXV93_RS08420	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV93_RS08425	COG2205	protein histidine kinase activity
NXV93_RS08425	COG3292	Two component regulator propeller
NXV93_RS08425	COG0745	RESPONSE REGULATOR receiver
NXV93_RS08440	COG2205	protein histidine kinase activity
NXV93_RS08440	COG0745	RESPONSE REGULATOR receiver
NXV93_RS08440	COG3292	Two component regulator propeller
NXV93_RS08440	COG2205	protein histidine kinase activity
NXV93_RS08440	COG0745	RESPONSE REGULATOR receiver
NXV93_RS08440	COG3292	Two component regulator propeller
NXV93_RS08450	COG1629	transport
NXV93_RS08455	COG1629	transport
NXV93_RS08460	COG0561	phosphatase activity
NXV93_RS08490	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXV93_RS08505	COG2211	Major facilitator Superfamily
NXV93_RS08515	COG1215	transferase activity, transferring glycosyl groups
NXV93_RS08520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXV93_RS08575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXV93_RS08580	COG0589	response to stress
NXV93_RS08580	COG0475	glutathione-regulated potassium exporter activity
NXV93_RS08585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXV93_RS08590	COG1136	(ABC) transporter
NXV93_RS08600	COG0733	neurotransmitter:sodium symporter activity
NXV93_RS08610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXV93_RS08615	COG5002	protein histidine kinase activity
NXV93_RS08615	COG0784	Response regulator, receiver
NXV93_RS08620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXV93_RS08625	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXV93_RS08645	COG1082	Xylose isomerase domain protein TIM barrel
NXV93_RS08660	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS08665	COG3292	Two component regulator propeller
NXV93_RS08665	COG0745	RESPONSE REGULATOR receiver
NXV93_RS08665	COG2205	protein histidine kinase activity
NXV93_RS08705	COG1346	cytolysis
NXV93_RS08710	COG1380	Effector of murein hydrolase LrgA
NXV93_RS08715	COG0280	phosphate acetyltransferase
NXV93_RS08720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXV93_RS08735	COG2003	Belongs to the UPF0758 family
NXV93_RS08740	COG0745	RESPONSE REGULATOR receiver
NXV93_RS08740	COG2205	protein histidine kinase activity
NXV93_RS08740	COG3292	Two component regulator propeller
NXV93_RS08770	COG3250	beta-galactosidase activity
NXV93_RS08785	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXV93_RS08805	COG1629	transport
NXV93_RS08805	COG4206	TonB-dependent receptor
NXV93_RS08810	COG1082	Xylose isomerase domain protein TIM barrel
NXV93_RS08825	COG1785	Belongs to the alkaline phosphatase family
NXV93_RS08830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXV93_RS08835	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXV93_RS08840	COG0515	serine threonine protein kinase
NXV93_RS08840	COG2815	serine threonine protein kinase
NXV93_RS08845	COG0564	pseudouridine synthase activity
NXV93_RS08870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXV93_RS08875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXV93_RS08895	COG0436	Aminotransferase
NXV93_RS08905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXV93_RS08920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXV93_RS08925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXV93_RS08935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXV93_RS08935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXV93_RS08940	COG2890	protein-(glutamine-N5) methyltransferase activity
NXV93_RS08950	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXV93_RS08960	COG0165	Argininosuccinate lyase
NXV93_RS08985	COG1629	transport
NXV93_RS08985	COG4206	TonB-dependent receptor
NXV93_RS09020	COG3292	Two component regulator propeller
NXV93_RS09020	COG0745	RESPONSE REGULATOR receiver
NXV93_RS09020	COG2205	protein histidine kinase activity
NXV93_RS09030	COG1595	DNA-templated transcription, initiation
NXV93_RS09035	COG1629	transport
NXV93_RS09055	COG3458	cephalosporin-C deacetylase activity
NXV93_RS09110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXV93_RS09155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXV93_RS09195	COG1629	transport
NXV93_RS09210	COG4677	pectinesterase activity
NXV93_RS09215	COG3292	Two component regulator propeller
NXV93_RS09215	COG0745	RESPONSE REGULATOR receiver
NXV93_RS09215	COG2205	protein histidine kinase activity
NXV93_RS09225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXV93_RS09230	COG1917	Cupin 2, conserved barrel domain protein
NXV93_RS09230	COG1396	sequence-specific DNA binding
NXV93_RS09240	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXV93_RS09245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXV93_RS09250	COG0137	argininosuccinate synthase activity
NXV93_RS09260	COG1438	arginine binding
NXV93_RS09265	COG1070	Carbohydrate kinase
NXV93_RS09270	COG4806	L-rhamnose isomerase
NXV93_RS09280	COG0235	Class ii aldolase
NXV93_RS09285	COG1454	alcohol dehydrogenase
NXV93_RS09295	COG0745	RESPONSE REGULATOR receiver
NXV93_RS09295	COG3292	Two component regulator propeller
NXV93_RS09295	COG2205	protein histidine kinase activity
NXV93_RS09300	COG4771	TonB-dependent receptor
NXV93_RS09305	COG0702	epimerase
NXV93_RS09335	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS09365	COG0564	pseudouridine synthase activity
NXV93_RS09395	COG3537	Alpha-1,2-mannosidase
NXV93_RS09400	COG0745	RESPONSE REGULATOR receiver
NXV93_RS09400	COG2205	protein histidine kinase activity
NXV93_RS09400	COG3292	Two component regulator propeller
NXV93_RS09420	COG4771	TonB-dependent receptor
NXV93_RS09440	COG3119	arylsulfatase activity
NXV93_RS09445	COG2204	response regulator
NXV93_RS09450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXV93_RS09450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXV93_RS09455	COG0612	Peptidase, M16
NXV93_RS09460	COG0534	Mate efflux family protein
NXV93_RS09465	COG2205	protein histidine kinase activity
NXV93_RS09465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV93_RS09480	COG1629	transport
NXV93_RS09480	COG4206	TonB-dependent receptor
NXV93_RS09490	COG4771	TonB-dependent receptor
NXV93_RS09505	COG0612	Peptidase, M16
NXV93_RS09535	COG0488	(ABC) transporter
NXV93_RS09540	COG3590	peptidase
NXV93_RS09570	COG0772	Belongs to the SEDS family
NXV93_RS09580	COG1774	PSP1 C-terminal conserved region
NXV93_RS09585	COG0470	DNA polymerase III
NXV93_RS09590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXV93_RS09595	COG2193	ferroxidase activity
NXV93_RS09635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXV93_RS09640	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXV93_RS09645	COG1160	GTP binding
NXV93_RS09655	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXV93_RS09660	COG1127	ABC transporter
NXV93_RS09665	COG0724	RNA recognition motif
NXV93_RS09670	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXV93_RS09675	COG0740	serine-type endopeptidase activity
NXV93_RS09680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXV93_RS09685	COG0514	ATP-dependent DNA helicase (RecQ)
NXV93_RS09690	COG0517	IMP dehydrogenase activity
NXV93_RS09690	COG0516	GMP reductase activity
NXV93_RS09705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXV93_RS09720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXV93_RS09780	COG0110	maltose O-acetyltransferase activity
NXV93_RS09800	COG1187	pseudouridine synthase activity
NXV93_RS09805	COG0017	Asparaginyl-tRNA synthetase
NXV93_RS09815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS09820	COG3292	Two component regulator propeller
NXV93_RS09820	COG0745	RESPONSE REGULATOR receiver
NXV93_RS09820	COG2205	protein histidine kinase activity
NXV93_RS09850	COG4771	TonB-dependent receptor
NXV93_RS09855	COG0702	epimerase
NXV93_RS09860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXV93_RS09865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXV93_RS09870	COG0052	Belongs to the universal ribosomal protein uS2 family
NXV93_RS09875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXV93_RS09880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV93_RS09890	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXV93_RS09895	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXV93_RS09915	COG0482	sulfurtransferase activity
NXV93_RS09985	COG0358	DNA primase activity
NXV93_RS10130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV93_RS10130	COG2198	Histidine kinase
NXV93_RS10130	COG0784	Response regulator, receiver
NXV93_RS10130	COG2205	protein histidine kinase activity
NXV93_RS10150	COG0551	DNA topoisomerase type I activity
NXV93_RS10150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV93_RS10185	COG4974	Belongs to the 'phage' integrase family
NXV93_RS10190	COG1570	exodeoxyribonuclease VII activity
NXV93_RS10200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXV93_RS10210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXV93_RS10215	COG0489	protein tyrosine kinase activity
NXV93_RS10260	COG0039	L-malate dehydrogenase activity
NXV93_RS10275	COG4771	TonB-dependent receptor
NXV93_RS10315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXV93_RS10320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXV93_RS10325	COG0811	peptide transport
NXV93_RS10330	COG0848	biopolymer transport protein
NXV93_RS10345	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXV93_RS10350	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXV93_RS10355	COG0105	UTP biosynthetic process
NXV93_RS10360	COG0739	heme binding
NXV93_RS10375	COG0149	triose-phosphate isomerase activity
NXV93_RS10385	COG0302	gtp cyclohydrolase
NXV93_RS10390	COG0358	DNA primase activity
NXV93_RS10400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXV93_RS10420	COG0514	ATP-dependent DNA helicase (RecQ)
NXV93_RS10480	COG1215	transferase activity, transferring glycosyl groups
NXV93_RS10485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXV93_RS10500	COG0726	polysaccharide deacetylase
NXV93_RS10515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXV93_RS10520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXV93_RS10545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXV93_RS10550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXV93_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS10580	COG0009	L-threonylcarbamoyladenylate synthase
NXV93_RS10590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXV93_RS10595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXV93_RS10600	COG2333	competence protein COMEC
NXV93_RS10600	COG0658	competence protein
NXV93_RS10605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXV93_RS10615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXV93_RS10640	COG4771	TonB-dependent receptor
NXV93_RS10660	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV93_RS10665	COG3537	Alpha-1,2-mannosidase
NXV93_RS10690	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS10695	COG3279	Response regulator of the LytR AlgR family
NXV93_RS10700	COG3275	phosphorelay sensor kinase activity
NXV93_RS10715	COG0386	Belongs to the glutathione peroxidase family
NXV93_RS10725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXV93_RS10785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXV93_RS10795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXV93_RS10810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXV93_RS10815	COG0742	ribosomal rna small subunit methyltransferase
NXV93_RS10830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV93_RS10860	COG1629	transport
NXV93_RS10860	COG4206	TonB-dependent receptor
NXV93_RS10885	COG3537	Alpha-1,2-mannosidase
NXV93_RS10890	COG3537	Alpha-1,2-mannosidase
NXV93_RS10910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXV93_RS10945	COG0582	viral genome integration into host DNA
NXV93_RS10975	COG0739	heme binding
NXV93_RS10985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXV93_RS10990	COG1388	LysM domain
NXV93_RS10990	COG0741	lytic transglycosylase activity
NXV93_RS11000	COG1475	DNA binding
NXV93_RS11005	COG1192	Involved in chromosome partitioning
NXV93_RS11010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXV93_RS11015	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV93_RS11030	COG0575	Belongs to the CDS family
NXV93_RS11035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXV93_RS11050	COG1196	nuclear chromosome segregation
NXV93_RS11055	COG2239	Acts as a magnesium transporter
NXV93_RS11060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXV93_RS11070	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV93_RS11150	COG0668	transmembrane transport
NXV93_RS11155	COG0662	Cupin 2, conserved barrel domain protein
NXV93_RS11155	COG2207	Transcriptional regulator
NXV93_RS11180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV93_RS11185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXV93_RS11190	COG0713	ATP synthesis coupled electron transport
NXV93_RS11205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXV93_RS11210	COG0649	NAD binding
NXV93_RS11210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV93_RS11215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV93_RS11220	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV93_RS11255	COG3250	beta-galactosidase activity
NXV93_RS11265	COG3250	beta-galactosidase activity
NXV93_RS11285	COG0702	epimerase
NXV93_RS11300	COG4771	TonB-dependent receptor
NXV93_RS11305	COG0702	epimerase
NXV93_RS11350	COG4206	TonB-dependent receptor
NXV93_RS11350	COG1629	transport
NXV93_RS11370	COG3537	Alpha-1,2-mannosidase
NXV93_RS11385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXV93_RS11390	COG0569	domain protein
NXV93_RS11395	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXV93_RS11405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXV93_RS11410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXV93_RS11415	COG0805	protein transport
NXV93_RS11425	COG2271	Major facilitator Superfamily
NXV93_RS11430	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXV93_RS11435	COG3775	system Galactitol-specific IIC component
NXV93_RS11440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS11450	COG2755	lipolytic protein G-D-S-L family
NXV93_RS11455	COG2205	protein histidine kinase activity
NXV93_RS11455	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11455	COG3292	Two component regulator propeller
NXV93_RS11485	COG0702	epimerase
NXV93_RS11490	COG1629	transport
NXV93_RS11490	COG4206	TonB-dependent receptor
NXV93_RS11500	COG3279	Response regulator of the LytR AlgR family
NXV93_RS11525	COG4771	TonB-dependent receptor
NXV93_RS11530	COG0702	epimerase
NXV93_RS11545	COG4677	pectinesterase activity
NXV93_RS11565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXV93_RS11570	COG3292	Two component regulator propeller
NXV93_RS11570	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11570	COG2205	protein histidine kinase activity
NXV93_RS11575	COG1242	4 iron, 4 sulfur cluster binding
NXV93_RS11585	COG0363	glucosamine-6-phosphate deaminase activity
NXV93_RS11595	COG2755	lipolytic protein G-D-S-L family
NXV93_RS11595	COG0657	acetylesterase activity
NXV93_RS11600	COG0009	L-threonylcarbamoyladenylate synthase
NXV93_RS11610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV93_RS11615	COG0561	phosphatase activity
NXV93_RS11630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXV93_RS11655	COG2755	lipolytic protein G-D-S-L family
NXV93_RS11690	COG0702	epimerase
NXV93_RS11695	COG4771	TonB-dependent receptor
NXV93_RS11715	COG4771	TonB-dependent receptor
NXV93_RS11735	COG3401	FG-GAP repeat protein
NXV93_RS11750	COG2755	lipolytic protein G-D-S-L family
NXV93_RS11760	COG3401	FG-GAP repeat protein
NXV93_RS11770	COG3254	rhamnose metabolic process
NXV93_RS11775	COG2205	protein histidine kinase activity
NXV93_RS11775	COG3292	Two component regulator propeller
NXV93_RS11775	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11775	COG2205	protein histidine kinase activity
NXV93_RS11775	COG3292	Two component regulator propeller
NXV93_RS11775	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11780	COG2755	lipolytic protein G-D-S-L family
NXV93_RS11780	COG0657	acetylesterase activity
NXV93_RS11790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS11805	COG4771	TonB-dependent receptor
NXV93_RS11810	COG0702	epimerase
NXV93_RS11825	COG4771	TonB-dependent receptor
NXV93_RS11905	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11905	COG2205	protein histidine kinase activity
NXV93_RS11905	COG3292	Two component regulator propeller
NXV93_RS11905	COG0745	RESPONSE REGULATOR receiver
NXV93_RS11905	COG2205	protein histidine kinase activity
NXV93_RS11905	COG3292	Two component regulator propeller
NXV93_RS11925	COG0546	phosphoglycolate phosphatase activity
NXV93_RS11955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXV93_RS11965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXV93_RS11975	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXV93_RS11995	COG1629	transport
NXV93_RS12000	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXV93_RS12015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXV93_RS12015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXV93_RS12020	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV93_RS12025	COG1078	dGTPase activity
NXV93_RS12030	COG0284	orotidine-5'-phosphate decarboxylase activity
NXV93_RS12035	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXV93_RS12040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NXV93_RS12045	COG1704	LemA family
NXV93_RS12060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXV93_RS12070	COG2226	methyltransferase
NXV93_RS12075	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXV93_RS12080	COG1702	phosphate starvation-inducible protein PhoH
NXV93_RS12100	COG2268	Band 7 protein
NXV93_RS12110	COG0101	tRNA pseudouridine synthase activity
NXV93_RS12130	COG3250	beta-galactosidase activity
NXV93_RS12140	COG0673	inositol 2-dehydrogenase activity
NXV93_RS12145	COG0673	inositol 2-dehydrogenase activity
NXV93_RS12160	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXV93_RS12170	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXV93_RS12185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXV93_RS12190	COG0793	Belongs to the peptidase S41A family
NXV93_RS12195	COG2131	deaminase
NXV93_RS12205	COG0339	signal peptide processing
NXV93_RS12210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NXV93_RS12215	COG1970	mechanosensitive ion channel activity
NXV93_RS12220	COG0519	Catalyzes the synthesis of GMP from XMP
NXV93_RS12220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXV93_RS12245	COG0297	glycogen (starch) synthase activity
NXV93_RS12265	COG0297	glycogen (starch) synthase activity
NXV93_RS12270	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXV93_RS12275	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXV93_RS12280	COG0543	2 iron, 2 sulfur cluster binding
NXV93_RS12285	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXV93_RS12290	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXV93_RS12295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXV93_RS12310	COG0791	NLP P60 protein
NXV93_RS12325	COG0612	Peptidase, M16
NXV93_RS12330	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXV93_RS12335	COG1597	lipid kinase activity
NXV93_RS12340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXV93_RS12355	COG1136	(ABC) transporter
NXV93_RS12375	COG2211	Major facilitator Superfamily
NXV93_RS12380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXV93_RS12395	COG1674	ftsk spoiiie
NXV93_RS12405	COG0492	ferredoxin-NADP+ reductase activity
NXV93_RS12410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS12450	COG4206	TonB-dependent receptor
NXV93_RS12450	COG1629	transport
NXV93_RS12490	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV93_RS12490	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV93_RS12500	COG1234	tRNA 3'-trailer cleavage
NXV93_RS12505	COG2989	Protein conserved in bacteria
NXV93_RS12525	COG3956	TIGRFAM MazG family protein
NXV93_RS12540	COG0525	valine-tRNA ligase activity
NXV93_RS12550	COG1595	DNA-templated transcription, initiation
NXV93_RS12560	COG4206	TonB-dependent receptor
NXV93_RS12560	COG1629	transport
NXV93_RS12565	COG0702	epimerase
NXV93_RS12580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS12595	COG1595	DNA-templated transcription, initiation
NXV93_RS12605	COG1629	transport
NXV93_RS12605	COG4206	TonB-dependent receptor
NXV93_RS12615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS12640	COG0653	protein targeting
NXV93_RS12645	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXV93_RS12655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXV93_RS12680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXV93_RS12690	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXV93_RS12700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXV93_RS12705	COG2204	response regulator
NXV93_RS12745	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXV93_RS12745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXV93_RS12765	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXV93_RS12770	COG0563	adenylate kinase activity
NXV93_RS12775	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXV93_RS12790	COG0739	heme binding
NXV93_RS12890	COG3142	Participates in the control of copper homeostasis
NXV93_RS12895	COG1418	mRNA catabolic process
NXV93_RS12930	COG4771	TonB-dependent receptor
NXV93_RS12935	COG0702	epimerase
NXV93_RS12965	COG0246	Mannitol dehydrogenase
NXV93_RS12975	COG1063	alcohol dehydrogenase
NXV93_RS12985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXV93_RS12990	COG2832	Protein of unknown function (DUF454)
NXV93_RS13000	COG0602	queuosine metabolic process
NXV93_RS13005	COG0247	lactate metabolic process
NXV93_RS13010	COG1139	Iron-sulfur cluster binding protein
NXV93_RS13020	COG0351	phosphomethylpyrimidine kinase
NXV93_RS13025	COG1629	transport
NXV93_RS13040	COG4589	Belongs to the CDS family
NXV93_RS13050	COG2304	oxidoreductase activity
NXV93_RS13060	COG1393	Belongs to the ArsC family
NXV93_RS13085	COG2233	PERMEase
NXV93_RS13090	COG1509	lysine 2,3-aminomutase activity
NXV93_RS13100	COG1115	amino acid carrier protein
NXV93_RS13135	COG1285	pathogenesis
NXV93_RS13155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXV93_RS13160	COG1388	LysM domain
NXV93_RS13160	COG0741	lytic transglycosylase activity
NXV93_RS13200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXV93_RS13210	COG0534	Mate efflux family protein
NXV93_RS13220	COG0564	pseudouridine synthase activity
NXV93_RS13250	COG0346	lactoylglutathione lyase activity
NXV93_RS13260	COG0653	protein targeting
NXV93_RS13285	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NXV93_RS13305	COG0732	type I restriction modification DNA specificity domain
NXV93_RS13310	COG1401	restriction endodeoxyribonuclease activity
NXV93_RS13315	COG4268	DNA restriction-modification system
NXV93_RS13335	COG4771	TonB-dependent receptor
NXV93_RS13370	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV93_RS13375	COG1063	alcohol dehydrogenase
NXV93_RS13435	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NXV93_RS13450	COG3645	SOS response
NXV93_RS13475	COG0582	viral genome integration into host DNA
NXV93_RS13505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXV93_RS13510	COG0784	Response regulator, receiver
NXV93_RS13510	COG5002	protein histidine kinase activity
NXV93_RS13515	COG0702	epimerase
NXV93_RS13525	COG4864	UPF0365 protein
NXV93_RS13540	COG0037	tRNA processing
NXV93_RS13550	COG1477	protein flavinylation
NXV93_RS13555	COG1971	Probably functions as a manganese efflux pump
NXV93_RS13570	COG0463	Glycosyl transferase, family 2
NXV93_RS13590	COG0148	phosphopyruvate hydratase activity
NXV93_RS13600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXV93_RS13605	COG1082	Xylose isomerase domain protein TIM barrel
NXV93_RS13610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXV93_RS13615	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV93_RS13620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXV93_RS13625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXV93_RS13625	COG4651	solute:proton antiporter activity
NXV93_RS13635	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXV93_RS13640	COG0193	aminoacyl-tRNA hydrolase activity
NXV93_RS13645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXV93_RS13655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXV93_RS13670	COG0237	dephospho-CoA kinase activity
NXV93_RS13685	COG0542	response to heat
NXV93_RS13695	COG0583	DNA-binding transcription factor activity
NXV93_RS13725	COG2855	membrane
NXV93_RS13730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXV93_RS13735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXV93_RS13755	COG0443	Heat shock 70 kDa protein
NXV93_RS13765	COG4651	solute:proton antiporter activity
NXV93_RS13765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXV93_RS13770	COG0306	phosphate transporter
NXV93_RS13780	COG0586	Pfam SNARE associated Golgi protein
NXV93_RS13840	COG0038	chloride channel
NXV93_RS13850	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXV93_RS13875	COG3119	arylsulfatase activity
NXV93_RS13885	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS13890	COG0702	epimerase
NXV93_RS13895	COG4771	TonB-dependent receptor
NXV93_RS13905	COG5434	Belongs to the glycosyl hydrolase 28 family
NXV93_RS13915	COG3292	Two component regulator propeller
NXV93_RS13915	COG2205	protein histidine kinase activity
NXV93_RS13915	COG0745	RESPONSE REGULATOR receiver
NXV93_RS13920	COG2172	sigma factor antagonist activity
NXV93_RS13945	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXV93_RS13950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXV93_RS13965	COG2843	Capsule synthesis protein
NXV93_RS13980	COG3250	beta-galactosidase activity
NXV93_RS13995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS14000	COG1629	transport
NXV93_RS14000	COG4206	TonB-dependent receptor
NXV93_RS14010	COG0745	RESPONSE REGULATOR receiver
NXV93_RS14010	COG2205	protein histidine kinase activity
NXV93_RS14010	COG3292	Two component regulator propeller
NXV93_RS14050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXV93_RS14060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS14065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXV93_RS14130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXV93_RS14155	COG1760	l-serine dehydratase
NXV93_RS14160	COG0598	Magnesium transport protein CorA
NXV93_RS14165	COG1193	negative regulation of DNA recombination
NXV93_RS14175	COG4974	Belongs to the 'phage' integrase family
NXV93_RS14295	COG0551	DNA topoisomerase type I activity
NXV93_RS14295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV93_RS14320	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXV93_RS14340	COG2873	o-acetylhomoserine
NXV93_RS14355	COG2197	response regulator
NXV93_RS14360	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXV93_RS14365	COG0456	acetyltransferase
NXV93_RS14375	COG3189	MarR family transcriptional regulator
NXV93_RS14380	COG0561	phosphatase activity
NXV93_RS14385	COG1169	isochorismate synthase
NXV93_RS14390	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXV93_RS14395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXV93_RS14400	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS14415	COG1191	sigma factor activity
NXV93_RS14430	COG4206	TonB-dependent receptor
NXV93_RS14430	COG1629	transport
NXV93_RS14455	COG0783	Belongs to the Dps family
NXV93_RS14465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXV93_RS14485	COG1595	DNA-templated transcription, initiation
NXV93_RS14495	COG4771	TonB-dependent receptor
NXV93_RS14505	COG0584	glycerophosphoryl diester phosphodiesterase
NXV93_RS14515	COG0584	glycerophosphoryl diester phosphodiesterase
NXV93_RS14520	COG2271	Major facilitator Superfamily
NXV93_RS14560	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS14565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXV93_RS14640	COG2205	protein histidine kinase activity
NXV93_RS14640	COG3292	Two component regulator propeller
NXV93_RS14640	COG0745	RESPONSE REGULATOR receiver
NXV93_RS14650	COG1595	DNA-templated transcription, initiation
NXV93_RS14655	COG1629	transport
NXV93_RS14660	COG0561	phosphatase activity
NXV93_RS14695	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS14700	COG2207	Transcriptional regulator
NXV93_RS14700	COG0662	Cupin 2, conserved barrel domain protein
NXV93_RS14705	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS14755	COG4206	TonB-dependent receptor
NXV93_RS14755	COG1629	transport
NXV93_RS14790	COG1629	transport
NXV93_RS14815	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS14830	COG1253	flavin adenine dinucleotide binding
NXV93_RS14835	COG0501	Belongs to the peptidase M48B family
NXV93_RS14855	COG0793	Belongs to the peptidase S41A family
NXV93_RS14860	COG0482	sulfurtransferase activity
NXV93_RS14870	COG2197	response regulator
NXV93_RS14880	COG1757	Na H antiporter
NXV93_RS14890	COG2814	Major facilitator Superfamily
NXV93_RS14895	COG4953	penicillin-binding protein 1C
NXV93_RS14905	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV93_RS14955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXV93_RS14960	COG0646	methionine synthase
NXV93_RS14960	COG1410	methionine synthase
NXV93_RS14965	COG0778	Nitroreductase
NXV93_RS14980	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXV93_RS14985	COG0572	uridine kinase
NXV93_RS14995	COG4232	protein-disulfide reductase activity
NXV93_RS15000	COG1741	Belongs to the pirin family
NXV93_RS15015	COG4771	TonB-dependent receptor
NXV93_RS15020	COG0702	epimerase
NXV93_RS15045	COG2271	Major facilitator Superfamily
NXV93_RS15065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXV93_RS15070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXV93_RS15075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXV93_RS15080	COG0131	Imidazoleglycerol-phosphate dehydratase
NXV93_RS15090	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXV93_RS15090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV93_RS15095	COG4771	TonB-dependent receptor
NXV93_RS15145	COG1592	Rubrerythrin
NXV93_RS15145	COG1773	rubredoxin
NXV93_RS15160	COG3118	belongs to the thioredoxin family
NXV93_RS15175	COG3591	Belongs to the peptidase S1B family
NXV93_RS15180	COG3591	Belongs to the peptidase S1B family
NXV93_RS15185	COG0641	radical SAM
NXV93_RS15210	COG0420	3'-5' exonuclease activity
NXV93_RS15230	COG1410	methionine synthase
NXV93_RS15230	COG0646	methionine synthase
NXV93_RS15240	COG0463	Glycosyl transferase, family 2
NXV93_RS15250	COG1032	radical SAM domain protein
NXV93_RS15270	COG0363	glucosamine-6-phosphate deaminase activity
NXV93_RS15275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV93_RS15290	COG4974	Belongs to the 'phage' integrase family
NXV93_RS15310	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXV93_RS15350	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXV93_RS15365	COG2264	protein methyltransferase activity
NXV93_RS15385	COG0590	tRNA wobble adenosine to inosine editing
NXV93_RS15390	COG0673	inositol 2-dehydrogenase activity
NXV93_RS15395	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXV93_RS15445	COG4771	TonB-dependent receptor
NXV93_RS15515	COG5012	cobalamin binding
NXV93_RS15530	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NXV93_RS15535	COG0698	ribose 5-phosphate isomerase
NXV93_RS15540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NXV93_RS15555	COG1070	Carbohydrate kinase
NXV93_RS15560	COG2160	L-arabinose isomerase activity
NXV93_RS15570	COG2816	NAD+ diphosphatase activity
NXV93_RS15605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXV93_RS15620	COG1482	cell wall glycoprotein biosynthetic process
NXV93_RS15625	COG4974	Belongs to the 'phage' integrase family
NXV93_RS15690	COG1216	Glycosyl transferase, family 2
NXV93_RS15700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXV93_RS15725	COG1216	Glycosyl transferase, family 2
NXV93_RS15765	COG0297	glycogen (starch) synthase activity
NXV93_RS15770	COG0110	maltose O-acetyltransferase activity
NXV93_RS15775	COG0463	Glycosyl transferase, family 2
NXV93_RS15810	COG4221	oxidoreductase activity
NXV93_RS15820	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXV93_RS15825	COG3273	potassium ion transport
NXV93_RS15825	COG0471	metal ion transport
NXV93_RS15830	COG0529	Catalyzes the synthesis of activated sulfate
NXV93_RS15835	COG0175	sulfate reduction
NXV93_RS15840	COG2895	sulfate adenylyltransferase (ATP) activity
NXV93_RS15860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXV93_RS15865	COG0242	peptide deformylase activity
NXV93_RS15875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXV93_RS15880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXV93_RS15885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXV93_RS15890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXV93_RS15900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXV93_RS15905	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXV93_RS15920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXV93_RS15930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXV93_RS15970	COG1940	carbohydrate kinase activity
NXV93_RS15985	COG2814	Major facilitator Superfamily
NXV93_RS15995	COG1629	transport
NXV93_RS16055	COG1082	Xylose isomerase domain protein TIM barrel
NXV93_RS16070	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS16075	COG1649	PFAM Uncharacterised BCR, COG1649
NXV93_RS16105	COG1629	transport
NXV93_RS16130	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS16135	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS16140	COG4771	TonB-dependent receptor
NXV93_RS16145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS16150	COG4335	DNA alkylation repair
NXV93_RS16155	COG0393	Putative heavy-metal-binding
NXV93_RS16160	COG0484	heat shock protein binding
NXV93_RS16165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXV93_RS16170	COG0488	(ABC) transporter
NXV93_RS16205	COG2183	response to ionizing radiation
NXV93_RS16210	COG2202	Pas domain
NXV93_RS16210	COG2205	protein histidine kinase activity
NXV93_RS16215	COG0737	Belongs to the 5'-nucleotidase family
NXV93_RS16500	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXV93_RS16515	COG0490	domain, Protein
NXV93_RS16515	COG2985	domain, Protein
NXV93_RS16520	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXV93_RS16530	COG1022	Amp-dependent synthetase and ligase
NXV93_RS16535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS16540	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXV93_RS16545	COG1301	dicarboxylic acid transport
NXV93_RS16550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXV93_RS16555	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXV93_RS16560	COG0363	glucosamine-6-phosphate deaminase activity
NXV93_RS16565	COG2837	iron assimilation
NXV93_RS16575	COG3279	Response regulator of the LytR AlgR family
NXV93_RS16590	COG1136	(ABC) transporter
NXV93_RS16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV93_RS16620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXV93_RS16625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXV93_RS16650	COG0501	Belongs to the peptidase M48B family
NXV93_RS16655	COG1704	LemA family
NXV93_RS16665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXV93_RS16670	COG2885	chlorophyll binding
NXV93_RS16675	COG0534	Mate efflux family protein
NXV93_RS16680	COG0657	acetylesterase activity
NXV93_RS16680	COG2755	lipolytic protein G-D-S-L family
NXV93_RS16685	COG2205	protein histidine kinase activity
NXV93_RS16685	COG0784	Response regulator, receiver
NXV93_RS16810	COG0551	DNA topoisomerase type I activity
NXV93_RS16810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV93_RS17060	COG4974	Belongs to the 'phage' integrase family
NXV93_RS17065	COG3177	Filamentation induced by cAMP protein fic
NXV93_RS17120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV93_RS17120	COG0551	DNA topoisomerase type I activity
NXV93_RS17135	COG2815	serine threonine protein kinase
NXV93_RS17135	COG0515	serine threonine protein kinase
NXV93_RS17270	COG2003	Belongs to the UPF0758 family
NXV93_RS17280	COG4974	Belongs to the 'phage' integrase family
NXV93_RS17290	COG0488	(ABC) transporter
NXV93_RS17310	COG2198	Histidine kinase
NXV93_RS17310	COG2205	protein histidine kinase activity
NXV93_RS17310	COG0784	Response regulator, receiver
NXV93_RS17330	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS17340	COG1442	glycosyl transferase family 8
NXV93_RS17345	COG2244	polysaccharide biosynthetic process
NXV93_RS17350	COG1250	3-hydroxyacyl-CoA dehydrogenase
NXV93_RS17350	COG1024	Enoyl-CoA hydratase
NXV93_RS17395	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS17440	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXV93_RS17445	COG1805	sodium ion transport
NXV93_RS17450	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXV93_RS17475	COG0513	Belongs to the DEAD box helicase family
NXV93_RS17480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXV93_RS17495	COG1739	Uncharacterized protein family UPF0029
NXV93_RS17515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXV93_RS17515	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXV93_RS17520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXV93_RS17525	COG0357	Ribosomal RNA small subunit methyltransferase G
NXV93_RS17540	COG1408	metallophosphoesterase
NXV93_RS17560	COG2217	Heavy metal translocating P-type atpase
NXV93_RS17570	COG0321	lipoyl(octanoyl) transferase activity
NXV93_RS17580	COG0657	acetylesterase activity
NXV93_RS17580	COG2755	lipolytic protein G-D-S-L family
NXV93_RS17600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXV93_RS17610	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXV93_RS17625	COG1678	Uncharacterized ACR, COG1678
NXV93_RS17640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXV93_RS17645	COG0305	Participates in initiation and elongation during chromosome replication
NXV93_RS17660	COG3969	phosphoadenosine phosphosulfate
NXV93_RS17665	COG1475	DNA binding
NXV93_RS17735	COG0745	RESPONSE REGULATOR receiver
NXV93_RS17755	COG1074	ATP-dependent DNA helicase activity
NXV93_RS17795	COG1629	transport
NXV93_RS17795	COG4206	TonB-dependent receptor
NXV93_RS17805	COG1629	transport
NXV93_RS17805	COG4206	TonB-dependent receptor
NXV93_RS17840	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXV93_RS17845	COG3537	Alpha-1,2-mannosidase
NXV93_RS17860	COG4206	TonB-dependent receptor
NXV93_RS17860	COG1629	transport
NXV93_RS17865	COG0702	epimerase
NXV93_RS17890	COG3408	Glycogen debranching enzyme
NXV93_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS17915	COG3408	Glycogen debranching enzyme
NXV93_RS17925	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV93_RS17935	COG0167	dihydroorotate dehydrogenase activity
NXV93_RS17940	COG0657	acetylesterase activity
NXV93_RS17940	COG2755	lipolytic protein G-D-S-L family
NXV93_RS17980	COG1715	Restriction endonuclease
NXV93_RS17985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NXV93_RS18030	COG1629	transport
NXV93_RS18030	COG4206	TonB-dependent receptor
NXV93_RS18110	COG4232	protein-disulfide reductase activity
NXV93_RS18125	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS18140	COG3420	alginic acid biosynthetic process
NXV93_RS18165	COG4771	TonB-dependent receptor
NXV93_RS18185	COG3291	Pkd domain containing protein
NXV93_RS18195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXV93_RS18205	COG2731	YhcH YjgK YiaL family protein
NXV93_RS18210	COG2814	Major facilitator Superfamily
NXV93_RS18230	COG3250	beta-galactosidase activity
NXV93_RS18240	COG5002	protein histidine kinase activity
NXV93_RS18240	COG2205	protein histidine kinase activity
NXV93_RS18240	COG0784	Response regulator, receiver
NXV93_RS18250	COG3250	beta-galactosidase activity
NXV93_RS18255	COG3250	beta-galactosidase activity
NXV93_RS18260	COG0745	RESPONSE REGULATOR receiver
NXV93_RS18265	COG5002	protein histidine kinase activity
NXV93_RS18355	COG3250	beta-galactosidase activity
NXV93_RS18360	COG3292	Two component regulator propeller
NXV93_RS18360	COG2205	protein histidine kinase activity
NXV93_RS18360	COG0745	RESPONSE REGULATOR receiver
NXV93_RS18390	COG2966	Psort location CytoplasmicMembrane, score
NXV93_RS18405	COG0300	oxidoreductase activity
NXV93_RS18410	COG1011	Hydrolase
NXV93_RS18435	COG1733	regulation of RNA biosynthetic process
NXV93_RS18475	COG4206	TonB-dependent receptor
NXV93_RS18520	COG0442	prolyl-tRNA aminoacylation
NXV93_RS18525	COG0745	RESPONSE REGULATOR receiver
NXV93_RS18530	COG2205	protein histidine kinase activity
NXV93_RS18565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXV93_RS18575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXV93_RS18580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXV93_RS18590	COG0552	protein localization to endoplasmic reticulum
NXV93_RS18595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV93_RS18600	COG0776	regulation of translation
NXV93_RS18610	COG0714	Associated with various cellular activities
NXV93_RS18625	COG2304	oxidoreductase activity
NXV93_RS18675	COG0326	Molecular chaperone. Has ATPase activity
NXV93_RS18680	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXV93_RS18715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXV93_RS18720	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXV93_RS18725	COG0336	Belongs to the RNA methyltransferase TrmD family
NXV93_RS18730	COG0167	dihydroorotate dehydrogenase activity
NXV93_RS18735	COG0543	2 iron, 2 sulfur cluster binding
NXV93_RS18750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXV93_RS18765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV93_RS18770	COG1538	Outer membrane efflux protein
NXV93_RS18780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXV93_RS18785	COG1595	DNA-templated transcription, initiation
NXV93_RS18805	COG1132	(ABC) transporter
NXV93_RS18840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXV93_RS18850	COG0156	8-amino-7-oxononanoate synthase activity
NXV93_RS18865	COG0577	efflux transmembrane transporter activity
NXV93_RS18865	COG1136	(ABC) transporter
NXV93_RS18890	COG2204	response regulator
NXV93_RS18895	COG2205	protein histidine kinase activity
NXV93_RS18920	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXV93_RS18925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXV93_RS18945	COG3830	Belongs to the UPF0237 family
NXV93_RS18945	COG0560	Phosphoserine phosphatase
NXV93_RS18950	COG0513	Belongs to the DEAD box helicase family
NXV93_RS18980	COG0246	Mannitol dehydrogenase
NXV93_RS18990	COG1904	glucuronate isomerase
NXV93_RS19345	COG0484	heat shock protein binding
NXV93_RS19385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXV93_RS19390	COG0756	dUTP diphosphatase activity
NXV93_RS19565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NXV93_RS19620	COG0587	DNA-directed DNA polymerase activity
NXV93_RS19625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV93_RS19630	COG0587	DNA-directed DNA polymerase activity
NXV93_RS19710	COG4974	Belongs to the 'phage' integrase family
NXV93_RS19730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXV93_RS19750	COG3015	lipoprotein NlpE involved in copper resistance
NXV93_RS19775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXV93_RS19790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXV93_RS19800	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXV93_RS19810	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV93_RS19810	COG3153	acetyltransferase
NXV93_RS19825	COG0477	Major facilitator Superfamily
NXV93_RS19825	COG2814	Major facilitator Superfamily
NXV93_RS19830	COG2115	Belongs to the xylose isomerase family
NXV93_RS19845	COG0351	phosphomethylpyrimidine kinase
NXV93_RS19850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXV93_RS19855	COG0045	succinate-CoA ligase (ADP-forming) activity
NXV93_RS19860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXV93_RS19875	COG0724	RNA recognition motif
NXV93_RS19880	COG3279	Response regulator of the LytR AlgR family
NXV93_RS19915	COG0667	Aldo Keto reductase
NXV93_RS19920	COG2326	polyphosphate kinase activity
NXV93_RS20000	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXV93_RS20015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXV93_RS20040	COG1360	Flagellar Motor Protein
NXV93_RS20045	COG2205	protein histidine kinase activity
NXV93_RS20050	COG3250	beta-galactosidase activity
NXV93_RS20055	COG3119	arylsulfatase activity
NXV93_RS20060	COG0702	epimerase
NXV93_RS20065	COG1629	transport
NXV93_RS20065	COG4206	TonB-dependent receptor
NXV93_RS20095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXV93_RS20110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXV93_RS20120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NXV93_RS20185	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS20195	COG0110	maltose O-acetyltransferase activity
NXV93_RS20220	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXV93_RS20225	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS20230	COG5039	Polysaccharide pyruvyl transferase
NXV93_RS20240	COG1442	glycosyl transferase family 8
NXV93_RS20240	COG1216	Glycosyl transferase, family 2
NXV93_RS20260	COG4974	Belongs to the 'phage' integrase family
NXV93_RS20280	COG0540	Belongs to the ATCase OTCase family
NXV93_RS20285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXV93_RS20300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXV93_RS20305	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXV93_RS20310	COG2985	domain, Protein
NXV93_RS20355	COG2207	Transcriptional regulator
NXV93_RS20365	COG1690	Belongs to the RtcB family
NXV93_RS20370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXV93_RS20370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS20380	COG2431	L-lysine efflux transmembrane transporter activity
NXV93_RS20385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV93_RS20390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXV93_RS20395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXV93_RS20400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV93_RS20405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXV93_RS20410	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV93_RS20415	COG0356	it plays a direct role in the translocation of protons across the membrane
NXV93_RS20425	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXV93_RS20430	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXV93_RS20435	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXV93_RS20440	COG0454	-acetyltransferase
NXV93_RS20490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXV93_RS20500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXV93_RS20505	COG1011	Hydrolase
NXV93_RS20510	COG0534	Mate efflux family protein
NXV93_RS20520	COG0577	efflux transmembrane transporter activity
NXV93_RS20520	COG1136	(ABC) transporter
NXV93_RS20540	COG2204	response regulator
NXV93_RS20545	COG4191	Histidine kinase
NXV93_RS20555	COG1151	hydroxylamine reductase activity
NXV93_RS20560	COG2233	PERMEase
NXV93_RS20570	COG0318	PFAM AMP-dependent synthetase and ligase
NXV93_RS20575	COG1082	Xylose isomerase domain protein TIM barrel
NXV93_RS20580	COG0745	RESPONSE REGULATOR receiver
NXV93_RS20585	COG5002	protein histidine kinase activity
NXV93_RS20605	COG3118	belongs to the thioredoxin family
NXV93_RS20685	COG5002	protein histidine kinase activity
NXV93_RS20695	COG0352	thiamine-phosphate diphosphorylase activity
NXV93_RS20700	COG2022	thiamine diphosphate biosynthetic process
NXV93_RS20705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXV93_RS20715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXV93_RS20720	COG0352	thiamine-phosphate diphosphorylase activity
NXV93_RS20735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXV93_RS20735	COG0574	Belongs to the PEP-utilizing enzyme family
NXV93_RS20740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXV93_RS20745	COG0564	pseudouridine synthase activity
NXV93_RS20765	COG0024	Methionine aminopeptidase
NXV93_RS20775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXV93_RS20785	COG0481	GTPase activity
NXV93_RS20805	COG0432	Pfam Uncharacterised protein family UPF0047
NXV93_RS20810	COG0708	Exodeoxyribonuclease III
NXV93_RS20825	COG0217	transcriptional regulatory protein
NXV93_RS20830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV93_RS20830	COG0072	phenylalanine-tRNA ligase activity
NXV93_RS20835	COG0305	Participates in initiation and elongation during chromosome replication
NXV93_RS20840	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXV93_RS20850	COG4680	protein conserved in bacteria
NXV93_RS20855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXV93_RS20860	COG4657	Part of a membrane complex involved in electron transport
NXV93_RS20865	COG4660	Part of a membrane complex involved in electron transport
NXV93_RS20870	COG4659	FMN binding
NXV93_RS20875	COG4658	electron transport chain
NXV93_RS20880	COG4656	Part of a membrane complex involved in electron transport
NXV93_RS20970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS20975	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXV93_RS20980	COG0438	transferase activity, transferring glycosyl groups
NXV93_RS21040	COG0706	membrane insertase activity
NXV93_RS21045	COG0534	Mate efflux family protein
NXV93_RS21050	COG1506	peptidase
NXV93_RS21050	COG0823	Involved in the tonB-independent uptake of proteins
NXV93_RS21065	COG1983	PspC domain protein
NXV93_RS21080	COG3104	oligopeptide transport
NXV93_RS21085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXV93_RS21095	COG1388	LysM domain
NXV93_RS21095	COG3942	CHAP domain
NXV93_RS21125	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXV93_RS21130	COG0556	nucleotide-excision repair
NXV93_RS21140	COG2949	membrane
NXV93_RS21150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXV93_RS21160	COG0842	Transport permease protein
NXV93_RS21165	COG0842	Transport permease protein
NXV93_RS21170	COG1131	(ABC) transporter
NXV93_RS21175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV93_RS21185	COG1917	Cupin 2, conserved barrel domain protein
NXV93_RS21185	COG2207	Transcriptional regulator
NXV93_RS21200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXV93_RS21205	COG0505	Belongs to the CarA family
NXV93_RS21215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXV93_RS21220	COG0069	glutamate synthase activity
NXV93_RS21220	COG0067	glutamate synthase
NXV93_RS21220	COG0070	glutamate synthase
NXV93_RS21230	COG0367	asparagine synthase
NXV93_RS21250	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXV93_RS21255	COG0436	Aminotransferase
NXV93_RS21265	COG0347	Belongs to the P(II) protein family
NXV93_RS21270	COG0004	ammonium transporteR
NXV93_RS21330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXV93_RS21350	COG0490	domain, Protein
NXV93_RS21350	COG0471	metal ion transport
NXV93_RS21355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV93_RS21355	COG2205	protein histidine kinase activity
NXV93_RS21360	COG1979	alcohol dehydrogenase
NXV93_RS21370	COG0133	tryptophan synthase activity
NXV93_RS21375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXV93_RS21385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXV93_RS21390	COG0134	indole-3-glycerol-phosphate synthase activity
NXV93_RS21395	COG0135	phosphoribosylanthranilate isomerase activity
NXV93_RS21400	COG0159	tryptophan synthase activity
NXV93_RS21410	COG0252	asparaginase activity
NXV93_RS21420	COG0745	RESPONSE REGULATOR receiver
NXV93_RS21425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXV93_RS21440	COG2197	response regulator
NXV93_RS21450	COG0138	bifunctional purine biosynthesis protein purh
NXV93_RS21465	COG1730	sister chromatid segregation
NXV93_RS21470	COG3487	Iron-regulated protein
NXV93_RS21495	COG1333	cytochrome c biogenesis protein
NXV93_RS21495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXV93_RS21505	COG1132	(ABC) transporter
NXV93_RS21510	COG2375	cellular response to nickel ion
NXV93_RS21510	COG1132	(ABC) transporter
NXV93_RS21515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS21525	COG4771	TonB-dependent receptor
NXV93_RS21535	COG4771	TonB-dependent receptor
NXV93_RS21545	COG0490	domain, Protein
NXV93_RS21545	COG2985	domain, Protein
NXV93_RS21550	COG1230	cation diffusion facilitator family transporter
NXV93_RS21575	COG4771	TonB-dependent receptor
NXV93_RS21610	COG1609	Transcriptional regulator
NXV93_RS21615	COG2721	sulfolactate sulfo-lyase activity
NXV93_RS21650	COG4452	Inner membrane protein CreD
NXV93_RS21660	COG1733	regulation of RNA biosynthetic process
NXV93_RS21670	COG0784	Response regulator, receiver
NXV93_RS21670	COG5002	protein histidine kinase activity
NXV93_RS21670	COG2205	protein histidine kinase activity
NXV93_RS21675	COG2198	Histidine kinase
NXV93_RS21675	COG0784	Response regulator, receiver
NXV93_RS21675	COG2205	protein histidine kinase activity
NXV93_RS21675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV93_RS21685	COG0228	four-way junction DNA binding
NXV93_RS21695	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXV93_RS21705	COG1070	Carbohydrate kinase
NXV93_RS21715	COG0738	Major facilitator superfamily
NXV93_RS21775	COG1177	transmembrane transport
NXV93_RS21780	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXV93_RS21785	COG3842	ATPase activity
NXV93_RS21790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV93_RS21795	COG0058	SHG alpha-glucan phosphorylase activity
NXV93_RS21805	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV93_RS21825	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXV93_RS21880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXV93_RS21885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXV93_RS21890	COG4948	Mandelate Racemase Muconate Lactonizing
NXV93_RS21905	COG1295	ribonuclease BN
NXV93_RS21915	COG0778	Nitroreductase
NXV93_RS21925	COG0704	Plays a role in the regulation of phosphate uptake
NXV93_RS21930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXV93_RS21940	COG0573	inorganic phosphate transmembrane transporter activity
NXV93_RS21950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXV93_RS21960	COG0586	Pfam SNARE associated Golgi protein
NXV93_RS21970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXV93_RS21985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXV93_RS21990	COG0167	dihydroorotate dehydrogenase activity
NXV93_RS21995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXV93_RS22070	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS22080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXV93_RS22095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NXV93_RS22120	COG1216	Glycosyl transferase, family 2
NXV93_RS22130	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXV93_RS22185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXV93_RS22190	COG0497	DNA recombination
NXV93_RS22205	COG0592	DNA-directed DNA polymerase activity
NXV93_RS22220	COG0321	lipoyl(octanoyl) transferase activity
NXV93_RS22220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXV93_RS22225	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXV93_RS22235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV93_RS22240	COG0156	8-amino-7-oxononanoate synthase activity
NXV93_RS22260	COG0019	diaminopimelate decarboxylase activity
NXV93_RS22265	COG0527	aspartate kinase activity
NXV93_RS22270	COG2884	Cell division ATP-binding protein ftsE
NXV93_RS22280	COG0107	imidazoleglycerol-phosphate synthase activity
NXV93_RS22285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXV93_RS22290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXV93_RS22295	COG0788	formyltetrahydrofolate deformylase activity
NXV93_RS22310	COG0456	acetyltransferase
NXV93_RS22340	COG0671	phosphoesterase, PA-phosphatase related
NXV93_RS22350	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NXV93_RS22355	COG1924	4 iron, 4 sulfur cluster binding
NXV93_RS22380	COG0534	Mate efflux family protein
NXV93_RS22390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXV93_RS22405	COG4884	unkown
NXV93_RS22405	COG3831	ATPase activity
NXV93_RS22410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV93_RS22410	COG2885	chlorophyll binding
NXV93_RS22415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXV93_RS22415	COG1328	CTP reductase activity
NXV93_RS22425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXV93_RS22445	COG2814	Major facilitator Superfamily
NXV93_RS22460	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXV93_RS22485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NXV93_RS22505	COG2814	Major facilitator Superfamily
NXV93_RS22515	COG0778	Nitroreductase
NXV93_RS22525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXV93_RS22535	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXV93_RS22550	COG4771	TonB-dependent receptor
NXV93_RS22575	COG0702	epimerase
NXV93_RS22580	COG4771	TonB-dependent receptor
NXV93_RS22615	COG1162	GTPase activity
NXV93_RS22660	COG1312	Catalyzes the dehydration of D-mannonate
NXV93_RS22665	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS22670	COG1609	Transcriptional regulator
NXV93_RS22685	COG2223	nitrite transmembrane transporter activity
NXV93_RS22695	COG4771	TonB-dependent receptor
NXV93_RS22705	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXV93_RS22705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXV93_RS22720	COG2226	methyltransferase
NXV93_RS22735	COG0511	ligase activity, forming carbon-carbon bonds
NXV93_RS22740	COG0439	Biotin carboxylase
NXV93_RS22745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV93_RS22760	COG1620	l-lactate permease
NXV93_RS22785	COG1690	Belongs to the RtcB family
NXV93_RS22795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NXV93_RS22800	COG1819	glycosyl
NXV93_RS22820	COG4771	TonB-dependent receptor
NXV93_RS22855	COG0110	maltose O-acetyltransferase activity
NXV93_RS22865	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV93_RS22885	COG0702	epimerase
NXV93_RS22890	COG4206	TonB-dependent receptor
NXV93_RS22890	COG1629	transport
NXV93_RS22895	COG4771	TonB-dependent receptor
NXV93_RS22915	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NXV93_RS22935	COG1136	(ABC) transporter
NXV93_RS22935	COG0577	efflux transmembrane transporter activity
NXV93_RS22940	COG0577	efflux transmembrane transporter activity
NXV93_RS22940	COG1136	(ABC) transporter
NXV93_RS22960	COG3852	Histidine kinase
NXV93_RS22965	COG0628	permease
NXV93_RS22970	COG1215	transferase activity, transferring glycosyl groups
NXV93_RS22975	COG0456	acetyltransferase
NXV93_RS22980	COG0569	domain protein
NXV93_RS22980	COG0189	ligase activity
NXV93_RS22985	COG1136	(ABC) transporter
NXV93_RS22985	COG0577	efflux transmembrane transporter activity
NXV93_RS22990	COG0436	Aminotransferase
NXV93_RS23010	COG0488	(ABC) transporter
NXV93_RS23060	COG3033	Beta-eliminating lyase
NXV93_RS23085	COG0629	single-stranded DNA binding
NXV93_RS23090	COG1194	a g-specific adenine glycosylase
NXV93_RS23100	COG1530	ribonuclease E activity
NXV93_RS23170	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS23210	COG4771	TonB-dependent receptor
NXV93_RS23215	COG1979	alcohol dehydrogenase
NXV93_RS23230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXV93_RS23240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXV93_RS23255	COG4191	Histidine kinase
NXV93_RS23260	COG2204	response regulator
NXV93_RS23280	COG0577	efflux transmembrane transporter activity
NXV93_RS23305	COG1136	(ABC) transporter
NXV93_RS23315	COG1252	NADH dehydrogenase
NXV93_RS23320	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXV93_RS23325	COG0295	cytidine deaminase activity
NXV93_RS23335	COG3059	membrane
NXV93_RS23340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXV93_RS23345	COG0488	(ABC) transporter
NXV93_RS23370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXV93_RS23390	COG1629	transport
NXV93_RS23390	COG4206	TonB-dependent receptor
NXV93_RS23405	COG0686	Belongs to the AlaDH PNT family
NXV93_RS23445	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXV93_RS23465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXV93_RS23470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXV93_RS23485	COG1595	DNA-templated transcription, initiation
NXV93_RS23520	COG0702	epimerase
NXV93_RS23525	COG1629	transport
NXV93_RS23545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXV93_RS23550	COG1741	Belongs to the pirin family
NXV93_RS23555	COG0259	pyridoxamine-phosphate oxidase activity
NXV93_RS23570	COG0346	lactoylglutathione lyase activity
NXV93_RS23600	COG0784	Response regulator, receiver
NXV93_RS23600	COG2198	Histidine kinase
NXV93_RS23600	COG2205	protein histidine kinase activity
NXV93_RS23620	COG1918	ferrous iron import across plasma membrane
NXV93_RS23620	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXV93_RS23625	COG0037	tRNA processing
NXV93_RS23655	COG0534	Mate efflux family protein
NXV93_RS23660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXV93_RS23665	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXV93_RS23710	COG2003	Belongs to the UPF0758 family
NXV93_RS23785	COG1983	PspC domain protein
NXV93_RS23790	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXV93_RS23815	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV93_RS23865	COG0668	transmembrane transport
NXV93_RS23875	COG3250	beta-galactosidase activity
NXV93_RS23880	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS23900	COG1629	transport
NXV93_RS23900	COG4206	TonB-dependent receptor
NXV93_RS23920	COG0784	Response regulator, receiver
NXV93_RS23920	COG2205	protein histidine kinase activity
NXV93_RS23920	COG2198	Histidine kinase
NXV93_RS23925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXV93_RS23935	COG0745	RESPONSE REGULATOR receiver
NXV93_RS23935	COG3292	Two component regulator propeller
NXV93_RS23935	COG0745	RESPONSE REGULATOR receiver
NXV93_RS23935	COG2205	protein histidine kinase activity
NXV93_RS23935	COG3292	Two component regulator propeller
NXV93_RS23935	COG2205	protein histidine kinase activity
NXV93_RS23940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXV93_RS23945	COG1830	Aldolase
NXV93_RS23950	COG0588	phosphoglycerate mutase activity
NXV93_RS23965	COG4206	TonB-dependent receptor
NXV93_RS23965	COG1629	transport
NXV93_RS23985	COG1119	ATPase activity
NXV93_RS23990	COG3661	Belongs to the glycosyl hydrolase 67 family
NXV93_RS24005	COG2211	Major facilitator Superfamily
NXV93_RS24025	COG0561	phosphatase activity
NXV93_RS24030	COG1629	transport
NXV93_RS24030	COG4206	TonB-dependent receptor
NXV93_RS24045	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXV93_RS24095	COG4717	serine-type aminopeptidase activity
NXV93_RS24120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXV93_RS24125	COG2814	Major facilitator Superfamily
NXV93_RS24130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXV93_RS24135	COG0126	phosphoglycerate kinase activity
NXV93_RS24150	COG2311	Membrane
NXV93_RS24160	COG0424	maF-like protein
NXV93_RS24180	COG0778	Nitroreductase
NXV93_RS24190	COG0288	reversible hydration of carbon dioxide
NXV93_RS24200	COG1629	transport
NXV93_RS24215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV93_RS24225	COG0511	ligase activity, forming carbon-carbon bonds
NXV93_RS24230	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXV93_RS24240	COG0191	fructose-bisphosphate aldolase activity
NXV93_RS24245	COG0254	rRNA binding
NXV93_RS24250	COG1373	ATPase (AAA superfamily
NXV93_RS24290	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXV93_RS24295	COG0511	ligase activity, forming carbon-carbon bonds
NXV93_RS24315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXV93_RS24330	COG1280	lysine exporter protein (LysE YggA)
NXV93_RS24355	COG1649	PFAM Uncharacterised BCR, COG1649
NXV93_RS24375	COG1966	Carbon starvation protein
NXV93_RS24380	COG1649	PFAM Uncharacterised BCR, COG1649
NXV93_RS24400	COG2113	Glycine betaine
NXV93_RS24405	COG4176	ABC-type proline glycine betaine transport system permease component
NXV93_RS24415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXV93_RS24425	COG2205	protein histidine kinase activity
NXV93_RS24425	COG0745	RESPONSE REGULATOR receiver
NXV93_RS24425	COG3292	Two component regulator propeller
NXV93_RS24430	COG4206	TonB-dependent receptor
NXV93_RS24430	COG1629	transport
NXV93_RS24445	COG1621	beta-fructofuranosidase activity
NXV93_RS24460	COG0561	phosphatase activity
NXV93_RS24465	COG4206	TonB-dependent receptor
NXV93_RS24465	COG1629	transport
NXV93_RS24480	COG1621	beta-fructofuranosidase activity
NXV93_RS24490	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXV93_RS24495	COG0475	glutathione-regulated potassium exporter activity
NXV93_RS24530	COG3279	Response regulator of the LytR AlgR family
NXV93_RS24590	COG4772	TonB-dependent receptor
NXV93_RS24615	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXV93_RS24620	COG1960	acyl-CoA dehydrogenase activity
NXV93_RS24625	COG0705	Rhomboid family
NXV93_RS24640	COG1956	GAF domain-containing protein
NXV93_RS24650	COG0484	heat shock protein binding
NXV93_RS24655	COG2194	sulfuric ester hydrolase activity
NXV93_RS24675	COG0028	Belongs to the TPP enzyme family
NXV93_RS24715	COG0459	protein refolding
NXV93_RS24720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXV93_RS24750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXV93_RS24760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXV93_RS24765	COG0124	histidyl-tRNA synthetase
NXV93_RS24780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXV93_RS24805	COG0514	ATP-dependent DNA helicase (RecQ)
NXV93_RS24815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXV93_RS24820	COG1368	sulfuric ester hydrolase activity
NXV93_RS24825	COG0671	phosphoesterase, PA-phosphatase related
NXV93_RS24830	COG0473	3-isopropylmalate dehydrogenase activity
NXV93_RS24840	COG0066	3-isopropylmalate dehydratase activity
NXV93_RS24845	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXV93_RS24850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXV93_RS24925	COG1028	Short-chain dehydrogenase reductase Sdr
NXV93_RS24945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXV93_RS24950	COG3118	belongs to the thioredoxin family
NXV93_RS24955	COG0439	Biotin carboxylase
NXV93_RS24965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV93_RS24975	COG2873	o-acetylhomoserine
NXV93_RS24980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXV93_RS25045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXV93_RS25050	COG1088	dTDP-glucose 4,6-dehydratase activity
NXV93_RS25055	COG1575	Belongs to the MenA family. Type 1 subfamily
NXV93_RS25060	COG1408	metallophosphoesterase
NXV93_RS25065	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXV93_RS25070	COG0194	GDP metabolic process
NXV93_RS25090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXV93_RS25095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXV93_RS25105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXV93_RS25110	COG0750	zinc metalloprotease
NXV93_RS25125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXV93_RS25135	COG2814	Major facilitator Superfamily
NXV93_RS25145	COG1328	CTP reductase activity
NXV93_RS25200	COG1629	transport
NXV93_RS25200	COG4206	TonB-dependent receptor
NXV93_RS25205	COG1629	transport
NXV93_RS25205	COG4206	TonB-dependent receptor
NXV93_RS25245	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV93_RS25265	COG1538	Outer membrane efflux protein
NXV93_RS25330	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV93_RS25345	COG0561	phosphatase activity
NXV93_RS25350	COG4771	TonB-dependent receptor
NXV93_RS25375	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXV93_RS25395	COG3550	peptidyl-serine autophosphorylation
NXV93_RS25420	COG1505	serine-type exopeptidase activity
NXV93_RS25435	COG3119	arylsulfatase activity
NXV93_RS25440	COG3119	arylsulfatase activity
NXV93_RS25450	COG0617	tRNA 3'-terminal CCA addition
NXV93_RS25470	COG0632	four-way junction helicase activity
NXV93_RS25475	COG0673	inositol 2-dehydrogenase activity
NXV93_RS25495	COG1272	protein, Hemolysin III
NXV93_RS25500	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXV93_RS25505	COG1629	transport
NXV93_RS25505	COG4206	TonB-dependent receptor
NXV93_RS25510	COG1629	transport
NXV93_RS25520	COG2204	response regulator
NXV93_RS25525	COG0488	(ABC) transporter
NXV93_RS25565	COG1595	DNA-templated transcription, initiation
NXV93_RS25575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXV93_RS25580	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXV93_RS25590	COG1522	sequence-specific DNA binding
NXV93_RS25620	COG0811	peptide transport
NXV93_RS25630	COG0084	hydrolase, TatD family'
NXV93_RS25650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXV93_RS25655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXV93_RS25660	COG0205	6-phosphofructokinase activity
NXV93_RS25695	COG0372	Belongs to the citrate synthase family
NXV93_RS25705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXV93_RS25710	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV93_RS25720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXV93_RS25740	COG0129	dihydroxy-acid dehydratase activity
NXV93_RS25750	COG3681	Belongs to the UPF0597 family
NXV93_RS25770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXV93_RS25825	COG1629	transport
NXV93_RS25825	COG4206	TonB-dependent receptor
NXV93_RS25845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV93_RS25845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV93_RS25850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV93_RS25855	COG2985	domain, Protein
NXV93_RS25855	COG0569	domain protein
NXV93_RS25870	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
NXV93_RS25875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NXV93_RS25895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXV93_RS25945	COG3537	Alpha-1,2-mannosidase
NXV93_RS25965	COG0702	epimerase
NXV93_RS25970	COG4771	TonB-dependent receptor
NXV93_RS25975	COG1940	carbohydrate kinase activity
NXV93_RS25985	COG2188	Transcriptional regulator
NXV93_RS26015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXV93_RS26025	COG1609	Transcriptional regulator
NXV93_RS26025	COG2207	Transcriptional regulator
NXV93_RS26030	COG0534	Mate efflux family protein
NXV93_RS26035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXV93_RS26040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXV93_RS26045	COG0166	Belongs to the GPI family
NXV93_RS26060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXV93_RS26080	COG2502	aspartate--ammonia ligase
NXV93_RS26085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXV93_RS26100	COG3876	Protein conserved in bacteria
NXV93_RS26110	COG2315	Protein conserved in bacteria
NXV93_RS26125	COG0860	N-Acetylmuramoyl-L-alanine amidase