locus-tag	class	description
FOC41_RS00015	COG0584	glycerophosphoryl diester phosphodiesterase
FOC41_RS00025	COG0584	glycerophosphoryl diester phosphodiesterase
FOC41_RS00030	COG2271	Major facilitator Superfamily
FOC41_RS00075	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS00080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FOC41_RS00085	COG1882	Formate acetyltransferase
FOC41_RS00155	COG3292	Two component regulator propeller
FOC41_RS00155	COG2205	protein histidine kinase activity
FOC41_RS00155	COG0745	RESPONSE REGULATOR receiver
FOC41_RS00165	COG1595	DNA-templated transcription, initiation
FOC41_RS00170	COG1629	transport
FOC41_RS00175	COG0561	phosphatase activity
FOC41_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS00210	COG2207	Transcriptional regulator
FOC41_RS00210	COG0662	Cupin 2, conserved barrel domain protein
FOC41_RS00215	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS00220	COG0656	L-ascorbic acid biosynthetic process
FOC41_RS00265	COG1629	transport
FOC41_RS00295	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS00310	COG1253	flavin adenine dinucleotide binding
FOC41_RS00315	COG0501	Belongs to the peptidase M48B family
FOC41_RS00340	COG0793	Belongs to the peptidase S41A family
FOC41_RS00345	COG0482	sulfurtransferase activity
FOC41_RS00350	COG2197	response regulator
FOC41_RS00360	COG1757	Na H antiporter
FOC41_RS00370	COG2814	Major facilitator Superfamily
FOC41_RS00375	COG4953	penicillin-binding protein 1C
FOC41_RS00380	COG2373	Large extracellular alpha-helical protein
FOC41_RS00385	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC41_RS00435	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOC41_RS00440	COG1410	methionine synthase
FOC41_RS00440	COG0646	methionine synthase
FOC41_RS00445	COG0778	Nitroreductase
FOC41_RS00450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC41_RS00455	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC41_RS00460	COG0572	uridine kinase
FOC41_RS00470	COG4232	protein-disulfide reductase activity
FOC41_RS00475	COG1741	Belongs to the pirin family
FOC41_RS00490	COG4771	TonB-dependent receptor
FOC41_RS00495	COG0702	epimerase
FOC41_RS00520	COG2271	Major facilitator Superfamily
FOC41_RS00540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOC41_RS00545	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOC41_RS00550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOC41_RS00555	COG0131	Imidazoleglycerol-phosphate dehydratase
FOC41_RS00565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOC41_RS00565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC41_RS00570	COG1629	transport
FOC41_RS00570	COG4206	TonB-dependent receptor
FOC41_RS00620	COG1773	rubredoxin
FOC41_RS00620	COG1592	Rubrerythrin
FOC41_RS00635	COG3118	belongs to the thioredoxin family
FOC41_RS00650	COG3591	Belongs to the peptidase S1B family
FOC41_RS00655	COG3591	Belongs to the peptidase S1B family
FOC41_RS00660	COG0641	radical SAM
FOC41_RS00685	COG0420	3'-5' exonuclease activity
FOC41_RS00705	COG0646	methionine synthase
FOC41_RS00705	COG1410	methionine synthase
FOC41_RS00715	COG0463	Glycosyl transferase, family 2
FOC41_RS00720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOC41_RS00725	COG1032	radical SAM domain protein
FOC41_RS00745	COG0363	glucosamine-6-phosphate deaminase activity
FOC41_RS00750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC41_RS00790	COG3292	Two component regulator propeller
FOC41_RS00790	COG0745	RESPONSE REGULATOR receiver
FOC41_RS00790	COG2205	protein histidine kinase activity
FOC41_RS00805	COG4771	TonB-dependent receptor
FOC41_RS00825	COG4771	TonB-dependent receptor
FOC41_RS00895	COG0811	peptide transport
FOC41_RS00900	COG0848	biopolymer transport protein
FOC41_RS00920	COG4206	TonB-dependent receptor
FOC41_RS00920	COG1629	transport
FOC41_RS00950	COG4974	Belongs to the 'phage' integrase family
FOC41_RS00975	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC41_RS01015	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOC41_RS01020	COG0022	dehydrogenase e1 component
FOC41_RS01030	COG2264	protein methyltransferase activity
FOC41_RS01050	COG0590	tRNA wobble adenosine to inosine editing
FOC41_RS01055	COG0673	inositol 2-dehydrogenase activity
FOC41_RS01060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOC41_RS01110	COG4771	TonB-dependent receptor
FOC41_RS01125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS01155	COG0110	maltose O-acetyltransferase activity
FOC41_RS01195	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS01200	COG5012	cobalamin binding
FOC41_RS01220	COG0698	ribose 5-phosphate isomerase
FOC41_RS01240	COG1070	Carbohydrate kinase
FOC41_RS01245	COG2160	L-arabinose isomerase activity
FOC41_RS01255	COG2816	NAD+ diphosphatase activity
FOC41_RS01285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FOC41_RS01300	COG1482	cell wall glycoprotein biosynthetic process
FOC41_RS01305	COG4974	Belongs to the 'phage' integrase family
FOC41_RS01370	COG1216	Glycosyl transferase, family 2
FOC41_RS01380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC41_RS01405	COG1216	Glycosyl transferase, family 2
FOC41_RS01445	COG0297	glycogen (starch) synthase activity
FOC41_RS01450	COG0110	maltose O-acetyltransferase activity
FOC41_RS01455	COG0463	Glycosyl transferase, family 2
FOC41_RS01485	COG4221	oxidoreductase activity
FOC41_RS01495	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOC41_RS01500	COG3273	potassium ion transport
FOC41_RS01500	COG0471	metal ion transport
FOC41_RS01505	COG0529	Catalyzes the synthesis of activated sulfate
FOC41_RS01510	COG0175	sulfate reduction
FOC41_RS01515	COG2895	sulfate adenylyltransferase (ATP) activity
FOC41_RS01535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOC41_RS01540	COG0242	peptide deformylase activity
FOC41_RS01550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOC41_RS01555	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOC41_RS01560	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOC41_RS01565	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOC41_RS01575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC41_RS01580	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOC41_RS01585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOC41_RS01585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC41_RS01585	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC41_RS01585	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC41_RS01595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOC41_RS01605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOC41_RS01620	COG1940	carbohydrate kinase activity
FOC41_RS01635	COG2814	Major facilitator Superfamily
FOC41_RS01650	COG1629	transport
FOC41_RS01670	COG1649	PFAM Uncharacterised BCR, COG1649
FOC41_RS01675	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS01690	COG1082	Xylose isomerase domain protein TIM barrel
FOC41_RS01715	COG3345	alpha-galactosidase
FOC41_RS01755	COG1629	transport
FOC41_RS01780	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS01785	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS01790	COG4771	TonB-dependent receptor
FOC41_RS01795	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS01800	COG4335	DNA alkylation repair
FOC41_RS01805	COG0393	Putative heavy-metal-binding
FOC41_RS01810	COG0484	heat shock protein binding
FOC41_RS01815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOC41_RS01820	COG0488	(ABC) transporter
FOC41_RS01855	COG2183	response to ionizing radiation
FOC41_RS01860	COG2202	Pas domain
FOC41_RS01860	COG2205	protein histidine kinase activity
FOC41_RS01865	COG0737	Belongs to the 5'-nucleotidase family
FOC41_RS01910	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FOC41_RS01925	COG2985	domain, Protein
FOC41_RS01925	COG0490	domain, Protein
FOC41_RS01930	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FOC41_RS01945	COG0318	PFAM AMP-dependent synthetase and ligase
FOC41_RS01950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC41_RS01955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOC41_RS01960	COG1301	dicarboxylic acid transport
FOC41_RS01965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FOC41_RS01970	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOC41_RS01975	COG0363	glucosamine-6-phosphate deaminase activity
FOC41_RS01980	COG2837	iron assimilation
FOC41_RS01990	COG3279	Response regulator of the LytR AlgR family
FOC41_RS02000	COG1136	(ABC) transporter
FOC41_RS02000	COG0577	efflux transmembrane transporter activity
FOC41_RS02005	COG1136	(ABC) transporter
FOC41_RS02010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS02035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC41_RS02040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC41_RS02065	COG0501	Belongs to the peptidase M48B family
FOC41_RS02070	COG1704	LemA family
FOC41_RS02080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC41_RS02085	COG2885	chlorophyll binding
FOC41_RS02090	COG0534	Mate efflux family protein
FOC41_RS02095	COG0657	acetylesterase activity
FOC41_RS02095	COG2755	lipolytic protein G-D-S-L family
FOC41_RS02100	COG2205	protein histidine kinase activity
FOC41_RS02100	COG5002	protein histidine kinase activity
FOC41_RS02100	COG0784	Response regulator, receiver
FOC41_RS02110	COG0488	(ABC) transporter
FOC41_RS02125	COG2205	protein histidine kinase activity
FOC41_RS02125	COG0784	Response regulator, receiver
FOC41_RS02125	COG5002	protein histidine kinase activity
FOC41_RS02145	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS02155	COG1442	glycosyl transferase family 8
FOC41_RS02160	COG2244	polysaccharide biosynthetic process
FOC41_RS02165	COG1216	Glycosyl transferase, family 2
FOC41_RS02165	COG1442	glycosyl transferase family 8
FOC41_RS02210	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS02260	COG1805	sodium ion transport
FOC41_RS02265	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FOC41_RS02280	COG2871	sodium ion transport
FOC41_RS02290	COG0513	Belongs to the DEAD box helicase family
FOC41_RS02295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOC41_RS02310	COG1739	Uncharacterized protein family UPF0029
FOC41_RS02325	COG0778	Nitroreductase
FOC41_RS02330	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC41_RS02330	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOC41_RS02335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOC41_RS02340	COG0357	Ribosomal RNA small subunit methyltransferase G
FOC41_RS02355	COG1408	metallophosphoesterase
FOC41_RS02375	COG2217	Heavy metal translocating P-type atpase
FOC41_RS02385	COG0321	lipoyl(octanoyl) transferase activity
FOC41_RS02395	COG2755	lipolytic protein G-D-S-L family
FOC41_RS02395	COG0657	acetylesterase activity
FOC41_RS02415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOC41_RS02425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOC41_RS02440	COG1678	Uncharacterized ACR, COG1678
FOC41_RS02455	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC41_RS02460	COG0305	Participates in initiation and elongation during chromosome replication
FOC41_RS02475	COG3969	phosphoadenosine phosphosulfate
FOC41_RS02480	COG1475	DNA binding
FOC41_RS02545	COG0745	RESPONSE REGULATOR receiver
FOC41_RS02565	COG1074	ATP-dependent DNA helicase activity
FOC41_RS02605	COG4206	TonB-dependent receptor
FOC41_RS02605	COG1629	transport
FOC41_RS02615	COG4206	TonB-dependent receptor
FOC41_RS02615	COG1629	transport
FOC41_RS02650	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC41_RS02655	COG3537	Alpha-1,2-mannosidase
FOC41_RS02670	COG4206	TonB-dependent receptor
FOC41_RS02670	COG1629	transport
FOC41_RS02675	COG0702	epimerase
FOC41_RS02700	COG3408	Glycogen debranching enzyme
FOC41_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS02725	COG3408	Glycogen debranching enzyme
FOC41_RS02735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS02795	COG3586	endonuclease activity
FOC41_RS02810	COG1629	transport
FOC41_RS02810	COG4206	TonB-dependent receptor
FOC41_RS02875	COG4232	protein-disulfide reductase activity
FOC41_RS02890	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS02905	COG3420	alginic acid biosynthetic process
FOC41_RS02925	COG1629	transport
FOC41_RS02960	COG3250	beta-galactosidase activity
FOC41_RS02970	COG2205	protein histidine kinase activity
FOC41_RS02970	COG0784	Response regulator, receiver
FOC41_RS02980	COG3250	beta-galactosidase activity
FOC41_RS02985	COG3250	beta-galactosidase activity
FOC41_RS02990	COG0745	RESPONSE REGULATOR receiver
FOC41_RS02995	COG5002	protein histidine kinase activity
FOC41_RS03075	COG0776	regulation of translation
FOC41_RS03090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC41_RS03120	COG3250	beta-galactosidase activity
FOC41_RS03125	COG0745	RESPONSE REGULATOR receiver
FOC41_RS03125	COG2205	protein histidine kinase activity
FOC41_RS03125	COG3292	Two component regulator propeller
FOC41_RS03155	COG2966	Psort location CytoplasmicMembrane, score
FOC41_RS03170	COG0300	oxidoreductase activity
FOC41_RS03180	COG1011	Hydrolase
FOC41_RS03265	COG4206	TonB-dependent receptor
FOC41_RS03275	COG3292	Two component regulator propeller
FOC41_RS03275	COG2205	protein histidine kinase activity
FOC41_RS03275	COG0745	RESPONSE REGULATOR receiver
FOC41_RS03275	COG3292	Two component regulator propeller
FOC41_RS03275	COG2205	protein histidine kinase activity
FOC41_RS03275	COG0745	RESPONSE REGULATOR receiver
FOC41_RS03310	COG0442	prolyl-tRNA aminoacylation
FOC41_RS03315	COG0745	RESPONSE REGULATOR receiver
FOC41_RS03320	COG2205	protein histidine kinase activity
FOC41_RS03355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOC41_RS03365	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOC41_RS03370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOC41_RS03380	COG0552	protein localization to endoplasmic reticulum
FOC41_RS03385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC41_RS03390	COG0776	regulation of translation
FOC41_RS03400	COG0714	Associated with various cellular activities
FOC41_RS03415	COG2304	oxidoreductase activity
FOC41_RS03465	COG0326	Molecular chaperone. Has ATPase activity
FOC41_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOC41_RS03505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC41_RS03510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOC41_RS03515	COG0336	Belongs to the RNA methyltransferase TrmD family
FOC41_RS03520	COG0167	dihydroorotate dehydrogenase activity
FOC41_RS03525	COG0543	2 iron, 2 sulfur cluster binding
FOC41_RS03540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC41_RS03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS03560	COG1538	Outer membrane efflux protein
FOC41_RS03570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOC41_RS03575	COG1595	DNA-templated transcription, initiation
FOC41_RS03595	COG3842	ATPase activity
FOC41_RS03625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOC41_RS03630	COG1597	lipid kinase activity
FOC41_RS03635	COG0156	8-amino-7-oxononanoate synthase activity
FOC41_RS03655	COG2226	methyltransferase
FOC41_RS03675	COG0592	DNA-directed DNA polymerase activity
FOC41_RS03700	COG0305	Participates in initiation and elongation during chromosome replication
FOC41_RS04040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FOC41_RS04045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOC41_RS04065	COG0560	Phosphoserine phosphatase
FOC41_RS04065	COG3830	Belongs to the UPF0237 family
FOC41_RS04070	COG0513	Belongs to the DEAD box helicase family
FOC41_RS04100	COG0246	Mannitol dehydrogenase
FOC41_RS04105	COG1609	Transcriptional regulator
FOC41_RS04110	COG1904	glucuronate isomerase
FOC41_RS04160	COG1674	ftsk spoiiie
FOC41_RS04185	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FOC41_RS04315	COG2135	peptidase activity
FOC41_RS04460	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS04520	COG0740	serine-type endopeptidase activity
FOC41_RS04685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC41_RS04705	COG3015	lipoprotein NlpE involved in copper resistance
FOC41_RS04730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC41_RS04745	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOC41_RS04755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOC41_RS04765	COG3153	acetyltransferase
FOC41_RS04765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOC41_RS04775	COG0477	Major facilitator Superfamily
FOC41_RS04775	COG2814	Major facilitator Superfamily
FOC41_RS04780	COG2115	Belongs to the xylose isomerase family
FOC41_RS04795	COG0351	phosphomethylpyrimidine kinase
FOC41_RS04800	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOC41_RS04805	COG0045	succinate-CoA ligase (ADP-forming) activity
FOC41_RS04810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOC41_RS04820	COG0724	RNA recognition motif
FOC41_RS04825	COG3279	Response regulator of the LytR AlgR family
FOC41_RS04860	COG0667	Aldo Keto reductase
FOC41_RS04865	COG2326	polyphosphate kinase activity
FOC41_RS04880	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOC41_RS04885	COG0348	domain, Protein
FOC41_RS04905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC41_RS04920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC41_RS05100	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FOC41_RS05185	COG1360	Flagellar Motor Protein
FOC41_RS05190	COG2205	protein histidine kinase activity
FOC41_RS05195	COG3250	beta-galactosidase activity
FOC41_RS05200	COG3119	arylsulfatase activity
FOC41_RS05210	COG4206	TonB-dependent receptor
FOC41_RS05210	COG1629	transport
FOC41_RS05235	COG2205	protein histidine kinase activity
FOC41_RS05240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOC41_RS05255	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOC41_RS05265	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FOC41_RS05330	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS05340	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOC41_RS05385	COG4974	Belongs to the 'phage' integrase family
FOC41_RS05405	COG0540	Belongs to the ATCase OTCase family
FOC41_RS05410	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FOC41_RS05425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOC41_RS05430	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FOC41_RS05435	COG2985	domain, Protein
FOC41_RS05480	COG2207	Transcriptional regulator
FOC41_RS05495	COG1690	Belongs to the RtcB family
FOC41_RS05500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC41_RS05500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC41_RS05510	COG2431	L-lysine efflux transmembrane transporter activity
FOC41_RS05515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC41_RS05520	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOC41_RS05525	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOC41_RS05530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC41_RS05535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOC41_RS05540	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC41_RS05545	COG0356	it plays a direct role in the translocation of protons across the membrane
FOC41_RS05555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOC41_RS05560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOC41_RS05565	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOC41_RS05570	COG0454	-acetyltransferase
FOC41_RS05575	COG2755	lipolytic protein G-D-S-L family
FOC41_RS05575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOC41_RS05610	COG0631	protein serine/threonine phosphatase activity
FOC41_RS05635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FOC41_RS05660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC41_RS05670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOC41_RS05675	COG1011	Hydrolase
FOC41_RS05680	COG0534	Mate efflux family protein
FOC41_RS05690	COG0577	efflux transmembrane transporter activity
FOC41_RS05690	COG1136	(ABC) transporter
FOC41_RS05710	COG2204	response regulator
FOC41_RS05715	COG4191	Histidine kinase
FOC41_RS05725	COG1151	hydroxylamine reductase activity
FOC41_RS05730	COG2233	PERMEase
FOC41_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
FOC41_RS05745	COG1082	Xylose isomerase domain protein TIM barrel
FOC41_RS05750	COG0745	RESPONSE REGULATOR receiver
FOC41_RS05755	COG5002	protein histidine kinase activity
FOC41_RS05775	COG3118	belongs to the thioredoxin family
FOC41_RS05855	COG5002	protein histidine kinase activity
FOC41_RS05865	COG0352	thiamine-phosphate diphosphorylase activity
FOC41_RS05870	COG2022	thiamine diphosphate biosynthetic process
FOC41_RS05875	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOC41_RS05885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOC41_RS05890	COG0352	thiamine-phosphate diphosphorylase activity
FOC41_RS05985	COG0758	DNA mediated transformation
FOC41_RS06020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOC41_RS06085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC41_RS06200	COG1192	Involved in chromosome partitioning
FOC41_RS06225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOC41_RS06225	COG0574	Belongs to the PEP-utilizing enzyme family
FOC41_RS06230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC41_RS06235	COG0564	pseudouridine synthase activity
FOC41_RS06255	COG0024	Methionine aminopeptidase
FOC41_RS06260	COG1322	Protein conserved in bacteria
FOC41_RS06270	COG0481	GTPase activity
FOC41_RS06300	COG0708	Exodeoxyribonuclease III
FOC41_RS06315	COG0217	transcriptional regulatory protein
FOC41_RS06320	COG0072	phenylalanine-tRNA ligase activity
FOC41_RS06320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC41_RS06325	COG0305	Participates in initiation and elongation during chromosome replication
FOC41_RS06330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOC41_RS06340	COG4680	protein conserved in bacteria
FOC41_RS06345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FOC41_RS06350	COG4657	Part of a membrane complex involved in electron transport
FOC41_RS06355	COG4660	Part of a membrane complex involved in electron transport
FOC41_RS06360	COG4659	FMN binding
FOC41_RS06365	COG4658	electron transport chain
FOC41_RS06370	COG4656	Part of a membrane complex involved in electron transport
FOC41_RS06425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC41_RS06450	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS06455	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS06460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC41_RS06505	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FOC41_RS06535	COG0504	CTP synthase activity
FOC41_RS06540	COG0706	membrane insertase activity
FOC41_RS06545	COG0534	Mate efflux family protein
FOC41_RS06550	COG1506	peptidase
FOC41_RS06550	COG0823	Involved in the tonB-independent uptake of proteins
FOC41_RS06565	COG1983	PspC domain protein
FOC41_RS06585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOC41_RS06595	COG1388	LysM domain
FOC41_RS06595	COG3942	CHAP domain
FOC41_RS06625	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FOC41_RS06630	COG0556	nucleotide-excision repair
FOC41_RS06640	COG2949	membrane
FOC41_RS06650	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC41_RS06660	COG0842	Transport permease protein
FOC41_RS06665	COG0842	Transport permease protein
FOC41_RS06670	COG1131	(ABC) transporter
FOC41_RS06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS06685	COG2207	Transcriptional regulator
FOC41_RS06685	COG1917	Cupin 2, conserved barrel domain protein
FOC41_RS06690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOC41_RS06690	COG0662	Cupin 2, conserved barrel domain protein
FOC41_RS06695	COG3119	arylsulfatase activity
FOC41_RS06705	COG3119	arylsulfatase activity
FOC41_RS06715	COG0702	epimerase
FOC41_RS06720	COG4771	TonB-dependent receptor
FOC41_RS06730	COG4771	TonB-dependent receptor
FOC41_RS06735	COG3119	arylsulfatase activity
FOC41_RS06740	COG3119	arylsulfatase activity
FOC41_RS06745	COG3250	beta-galactosidase activity
FOC41_RS06750	COG3119	arylsulfatase activity
FOC41_RS06760	COG0745	RESPONSE REGULATOR receiver
FOC41_RS06760	COG2205	protein histidine kinase activity
FOC41_RS06760	COG3292	Two component regulator propeller
FOC41_RS06780	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FOC41_RS06785	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FOC41_RS06805	COG0110	maltose O-acetyltransferase activity
FOC41_RS06810	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS06855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC41_RS06890	COG0505	Belongs to the CarA family
FOC41_RS06900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOC41_RS06905	COG0070	glutamate synthase
FOC41_RS06905	COG0069	glutamate synthase activity
FOC41_RS06905	COG0067	glutamate synthase
FOC41_RS06915	COG0367	asparagine synthase
FOC41_RS06930	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOC41_RS06935	COG0436	Aminotransferase
FOC41_RS06945	COG0347	Belongs to the P(II) protein family
FOC41_RS06950	COG0004	ammonium transporteR
FOC41_RS07010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC41_RS07030	COG0471	metal ion transport
FOC41_RS07030	COG0490	domain, Protein
FOC41_RS07035	COG2202	Pas domain
FOC41_RS07035	COG2205	protein histidine kinase activity
FOC41_RS07040	COG1979	alcohol dehydrogenase
FOC41_RS07050	COG0133	tryptophan synthase activity
FOC41_RS07055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOC41_RS07065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOC41_RS07070	COG0134	indole-3-glycerol-phosphate synthase activity
FOC41_RS07075	COG0135	phosphoribosylanthranilate isomerase activity
FOC41_RS07080	COG0159	tryptophan synthase activity
FOC41_RS07085	COG0252	asparaginase activity
FOC41_RS07095	COG0745	RESPONSE REGULATOR receiver
FOC41_RS07100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC41_RS07115	COG2197	response regulator
FOC41_RS07125	COG0138	bifunctional purine biosynthesis protein purh
FOC41_RS07130	COG0716	FMN binding
FOC41_RS07140	COG1730	sister chromatid segregation
FOC41_RS07145	COG3487	Iron-regulated protein
FOC41_RS07170	COG1333	cytochrome c biogenesis protein
FOC41_RS07170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC41_RS07180	COG1132	(ABC) transporter
FOC41_RS07185	COG2375	cellular response to nickel ion
FOC41_RS07185	COG1132	(ABC) transporter
FOC41_RS07190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS07200	COG4771	TonB-dependent receptor
FOC41_RS07210	COG4771	TonB-dependent receptor
FOC41_RS07220	COG0490	domain, Protein
FOC41_RS07220	COG2985	domain, Protein
FOC41_RS07225	COG1230	cation diffusion facilitator family transporter
FOC41_RS07465	COG4974	Belongs to the 'phage' integrase family
FOC41_RS07480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC41_RS07480	COG0551	DNA topoisomerase type I activity
FOC41_RS07495	COG4804	nuclease activity
FOC41_RS07540	COG4771	TonB-dependent receptor
FOC41_RS07575	COG1609	Transcriptional regulator
FOC41_RS07580	COG2721	sulfolactate sulfo-lyase activity
FOC41_RS07615	COG4452	Inner membrane protein CreD
FOC41_RS07625	COG1733	regulation of RNA biosynthetic process
FOC41_RS07635	COG0784	Response regulator, receiver
FOC41_RS07635	COG2205	protein histidine kinase activity
FOC41_RS07635	COG5002	protein histidine kinase activity
FOC41_RS07640	COG2205	protein histidine kinase activity
FOC41_RS07640	COG2198	Histidine kinase
FOC41_RS07640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC41_RS07640	COG0784	Response regulator, receiver
FOC41_RS07650	COG0228	four-way junction DNA binding
FOC41_RS07660	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FOC41_RS07670	COG1070	Carbohydrate kinase
FOC41_RS07680	COG0738	Major facilitator superfamily
FOC41_RS07685	COG2207	Transcriptional regulator
FOC41_RS07705	COG1177	transmembrane transport
FOC41_RS07710	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOC41_RS07715	COG3842	ATPase activity
FOC41_RS07720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC41_RS07725	COG0058	SHG alpha-glucan phosphorylase activity
FOC41_RS07735	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOC41_RS07755	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FOC41_RS07810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOC41_RS07815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOC41_RS07820	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS07835	COG1295	ribonuclease BN
FOC41_RS07860	COG0778	Nitroreductase
FOC41_RS07870	COG0704	Plays a role in the regulation of phosphate uptake
FOC41_RS07875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOC41_RS07880	COG0581	inorganic phosphate transmembrane transporter activity
FOC41_RS07885	COG0573	inorganic phosphate transmembrane transporter activity
FOC41_RS07895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC41_RS07905	COG0586	Pfam SNARE associated Golgi protein
FOC41_RS07915	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOC41_RS07930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOC41_RS07935	COG0167	dihydroorotate dehydrogenase activity
FOC41_RS07940	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOC41_RS07955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOC41_RS07955	COG0515	serine threonine protein kinase
FOC41_RS08015	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS08025	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS08045	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS08075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC41_RS08115	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC41_RS08550	COG1120	ATPase activity
FOC41_RS08555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC41_RS08690	COG0587	DNA-directed DNA polymerase activity
FOC41_RS08710	COG0587	DNA-directed DNA polymerase activity
FOC41_RS08815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC41_RS08840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOC41_RS08855	COG0297	glycogen (starch) synthase activity
FOC41_RS08855	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS08865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOC41_RS08915	COG0776	regulation of translation
FOC41_RS08940	COG1442	glycosyl transferase family 8
FOC41_RS08970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC41_RS08990	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOC41_RS09020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOC41_RS09025	COG0497	DNA recombination
FOC41_RS09040	COG0592	DNA-directed DNA polymerase activity
FOC41_RS09055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOC41_RS09055	COG0321	lipoyl(octanoyl) transferase activity
FOC41_RS09060	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOC41_RS09070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOC41_RS09075	COG0156	8-amino-7-oxononanoate synthase activity
FOC41_RS09085	COG5002	protein histidine kinase activity
FOC41_RS09095	COG0019	diaminopimelate decarboxylase activity
FOC41_RS09100	COG0527	aspartate kinase activity
FOC41_RS09105	COG2884	Cell division ATP-binding protein ftsE
FOC41_RS09110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOC41_RS09110	COG0140	phosphoribosyl-ATP diphosphatase activity
FOC41_RS09115	COG0107	imidazoleglycerol-phosphate synthase activity
FOC41_RS09120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOC41_RS09125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOC41_RS09130	COG0788	formyltetrahydrofolate deformylase activity
FOC41_RS09145	COG0456	acetyltransferase
FOC41_RS09175	COG1924	4 iron, 4 sulfur cluster binding
FOC41_RS09200	COG0534	Mate efflux family protein
FOC41_RS09210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC41_RS09225	COG3831	ATPase activity
FOC41_RS09225	COG4884	unkown
FOC41_RS09230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS09230	COG2885	chlorophyll binding
FOC41_RS09235	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOC41_RS09235	COG1328	CTP reductase activity
FOC41_RS09245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC41_RS09265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC41_RS09290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOC41_RS09310	COG2814	Major facilitator Superfamily
FOC41_RS09315	COG0656	L-ascorbic acid biosynthetic process
FOC41_RS09320	COG0778	Nitroreductase
FOC41_RS09330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC41_RS09340	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FOC41_RS09355	COG4771	TonB-dependent receptor
FOC41_RS09385	COG0702	epimerase
FOC41_RS09390	COG4771	TonB-dependent receptor
FOC41_RS09425	COG1162	GTPase activity
FOC41_RS09470	COG1312	Catalyzes the dehydration of D-mannonate
FOC41_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS09480	COG1609	Transcriptional regulator
FOC41_RS09495	COG2223	nitrite transmembrane transporter activity
FOC41_RS09505	COG4771	TonB-dependent receptor
FOC41_RS09515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC41_RS09515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOC41_RS09530	COG2226	methyltransferase
FOC41_RS09545	COG0511	ligase activity, forming carbon-carbon bonds
FOC41_RS09550	COG0439	Biotin carboxylase
FOC41_RS09555	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC41_RS09570	COG1620	l-lactate permease
FOC41_RS09595	COG1690	Belongs to the RtcB family
FOC41_RS09605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOC41_RS09610	COG1819	glycosyl
FOC41_RS09640	COG4771	TonB-dependent receptor
FOC41_RS09675	COG0110	maltose O-acetyltransferase activity
FOC41_RS09685	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS09705	COG0702	epimerase
FOC41_RS09710	COG4771	TonB-dependent receptor
FOC41_RS09725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOC41_RS09730	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FOC41_RS09745	COG0577	efflux transmembrane transporter activity
FOC41_RS09745	COG1136	(ABC) transporter
FOC41_RS09750	COG0577	efflux transmembrane transporter activity
FOC41_RS09750	COG1136	(ABC) transporter
FOC41_RS09770	COG3852	Histidine kinase
FOC41_RS09775	COG0628	permease
FOC41_RS09780	COG1215	transferase activity, transferring glycosyl groups
FOC41_RS09785	COG0456	acetyltransferase
FOC41_RS09790	COG0569	domain protein
FOC41_RS09790	COG0189	ligase activity
FOC41_RS09795	COG0577	efflux transmembrane transporter activity
FOC41_RS09795	COG1136	(ABC) transporter
FOC41_RS09800	COG0436	Aminotransferase
FOC41_RS09820	COG0488	(ABC) transporter
FOC41_RS09835	COG0745	RESPONSE REGULATOR receiver
FOC41_RS09890	COG0629	single-stranded DNA binding
FOC41_RS09895	COG1194	a g-specific adenine glycosylase
FOC41_RS09905	COG1530	ribonuclease E activity
FOC41_RS09960	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS09995	COG4771	TonB-dependent receptor
FOC41_RS10000	COG1979	alcohol dehydrogenase
FOC41_RS10015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOC41_RS10025	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOC41_RS10040	COG4191	Histidine kinase
FOC41_RS10045	COG2204	response regulator
FOC41_RS10065	COG0577	efflux transmembrane transporter activity
FOC41_RS10085	COG1136	(ABC) transporter
FOC41_RS10095	COG1252	NADH dehydrogenase
FOC41_RS10100	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOC41_RS10105	COG0295	cytidine deaminase activity
FOC41_RS10115	COG3059	membrane
FOC41_RS10120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC41_RS10130	COG0488	(ABC) transporter
FOC41_RS10155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC41_RS10175	COG1629	transport
FOC41_RS10175	COG4206	TonB-dependent receptor
FOC41_RS10190	COG0686	Belongs to the AlaDH PNT family
FOC41_RS10230	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOC41_RS10240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOC41_RS10245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOC41_RS10260	COG4974	Belongs to the 'phage' integrase family
FOC41_RS10300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOC41_RS10300	COG0551	DNA topoisomerase type I activity
FOC41_RS10320	COG2198	Histidine kinase
FOC41_RS10320	COG0784	Response regulator, receiver
FOC41_RS10320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC41_RS10320	COG2205	protein histidine kinase activity
FOC41_RS10445	COG0358	DNA primase activity
FOC41_RS10515	COG1595	DNA-templated transcription, initiation
FOC41_RS10530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOC41_RS10535	COG1741	Belongs to the pirin family
FOC41_RS10540	COG0259	pyridoxamine-phosphate oxidase activity
FOC41_RS10555	COG0346	lactoylglutathione lyase activity
FOC41_RS10605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FOC41_RS10605	COG1918	ferrous iron import across plasma membrane
FOC41_RS10610	COG0037	tRNA processing
FOC41_RS10625	COG3119	arylsulfatase activity
FOC41_RS10630	COG2205	protein histidine kinase activity
FOC41_RS10635	COG2205	protein histidine kinase activity
FOC41_RS10635	COG2202	Pas domain
FOC41_RS10640	COG0534	Mate efflux family protein
FOC41_RS10645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOC41_RS10650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOC41_RS10695	COG2003	Belongs to the UPF0758 family
FOC41_RS10725	COG1983	PspC domain protein
FOC41_RS10735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOC41_RS10760	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC41_RS10780	COG1595	DNA-templated transcription, initiation
FOC41_RS10805	COG0668	transmembrane transport
FOC41_RS10815	COG3250	beta-galactosidase activity
FOC41_RS10820	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS10825	COG3119	arylsulfatase activity
FOC41_RS10840	COG1629	transport
FOC41_RS10840	COG4206	TonB-dependent receptor
FOC41_RS10865	COG2205	protein histidine kinase activity
FOC41_RS10865	COG2198	Histidine kinase
FOC41_RS10865	COG0784	Response regulator, receiver
FOC41_RS10870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOC41_RS10880	COG2205	protein histidine kinase activity
FOC41_RS10880	COG2205	protein histidine kinase activity
FOC41_RS10880	COG3292	Two component regulator propeller
FOC41_RS10880	COG0745	RESPONSE REGULATOR receiver
FOC41_RS10880	COG0745	RESPONSE REGULATOR receiver
FOC41_RS10880	COG3292	Two component regulator propeller
FOC41_RS10885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOC41_RS10890	COG1830	Aldolase
FOC41_RS10895	COG0588	phosphoglycerate mutase activity
FOC41_RS10910	COG1629	transport
FOC41_RS10910	COG4206	TonB-dependent receptor
FOC41_RS10930	COG1119	ATPase activity
FOC41_RS10935	COG3661	Belongs to the glycosyl hydrolase 67 family
FOC41_RS10950	COG2211	Major facilitator Superfamily
FOC41_RS10970	COG0561	phosphatase activity
FOC41_RS10975	COG1629	transport
FOC41_RS10975	COG4206	TonB-dependent receptor
FOC41_RS10985	COG1523	belongs to the glycosyl hydrolase 13 family
FOC41_RS10990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOC41_RS11030	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOC41_RS11040	COG2814	Major facilitator Superfamily
FOC41_RS11050	COG0126	phosphoglycerate kinase activity
FOC41_RS11065	COG2311	Membrane
FOC41_RS11075	COG0424	maF-like protein
FOC41_RS11095	COG0778	Nitroreductase
FOC41_RS11105	COG0288	reversible hydration of carbon dioxide
FOC41_RS11115	COG1629	transport
FOC41_RS11130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC41_RS11140	COG0511	ligase activity, forming carbon-carbon bonds
FOC41_RS11145	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOC41_RS11155	COG0191	fructose-bisphosphate aldolase activity
FOC41_RS11160	COG0254	rRNA binding
FOC41_RS11165	COG1373	ATPase (AAA superfamily
FOC41_RS11215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS11240	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FOC41_RS11245	COG0511	ligase activity, forming carbon-carbon bonds
FOC41_RS11265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOC41_RS11280	COG1280	lysine exporter protein (LysE YggA)
FOC41_RS11290	COG2205	protein histidine kinase activity
FOC41_RS11290	COG3292	Two component regulator propeller
FOC41_RS11290	COG2205	protein histidine kinase activity
FOC41_RS11290	COG0745	RESPONSE REGULATOR receiver
FOC41_RS11290	COG0745	RESPONSE REGULATOR receiver
FOC41_RS11290	COG3292	Two component regulator propeller
FOC41_RS11305	COG1649	PFAM Uncharacterised BCR, COG1649
FOC41_RS11335	COG1966	Carbon starvation protein
FOC41_RS11340	COG1649	PFAM Uncharacterised BCR, COG1649
FOC41_RS11375	COG2113	Glycine betaine
FOC41_RS11380	COG4176	ABC-type proline glycine betaine transport system permease component
FOC41_RS11390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOC41_RS11400	COG0745	RESPONSE REGULATOR receiver
FOC41_RS11400	COG2205	protein histidine kinase activity
FOC41_RS11400	COG3292	Two component regulator propeller
FOC41_RS11405	COG4206	TonB-dependent receptor
FOC41_RS11405	COG1629	transport
FOC41_RS11425	COG1621	beta-fructofuranosidase activity
FOC41_RS11440	COG0561	phosphatase activity
FOC41_RS11445	COG1629	transport
FOC41_RS11445	COG4206	TonB-dependent receptor
FOC41_RS11460	COG1621	beta-fructofuranosidase activity
FOC41_RS11465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOC41_RS11475	COG3250	beta-galactosidase activity
FOC41_RS11480	COG3537	Alpha-1,2-mannosidase
FOC41_RS11490	COG1629	transport
FOC41_RS11515	COG3250	beta-galactosidase activity
FOC41_RS11525	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS11545	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS11595	COG3279	Response regulator of the LytR AlgR family
FOC41_RS11655	COG4772	TonB-dependent receptor
FOC41_RS11680	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FOC41_RS11685	COG1960	acyl-CoA dehydrogenase activity
FOC41_RS11690	COG0705	Rhomboid family
FOC41_RS11705	COG1956	GAF domain-containing protein
FOC41_RS11715	COG0484	heat shock protein binding
FOC41_RS11720	COG2194	sulfuric ester hydrolase activity
FOC41_RS11740	COG0028	Belongs to the TPP enzyme family
FOC41_RS11780	COG0459	protein refolding
FOC41_RS11785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOC41_RS11810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOC41_RS11820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC41_RS11825	COG0124	histidyl-tRNA synthetase
FOC41_RS11840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOC41_RS11865	COG0514	ATP-dependent DNA helicase (RecQ)
FOC41_RS11875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC41_RS11880	COG1368	sulfuric ester hydrolase activity
FOC41_RS11885	COG0671	phosphoesterase, PA-phosphatase related
FOC41_RS11890	COG0473	3-isopropylmalate dehydrogenase activity
FOC41_RS11900	COG0066	3-isopropylmalate dehydratase activity
FOC41_RS11905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC41_RS11910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC41_RS11960	COG1917	Cupin 2, conserved barrel domain protein
FOC41_RS11960	COG4977	sequence-specific DNA binding
FOC41_RS11990	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS12010	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FOC41_RS12015	COG3118	belongs to the thioredoxin family
FOC41_RS12020	COG0439	Biotin carboxylase
FOC41_RS12030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOC41_RS12040	COG2873	o-acetylhomoserine
FOC41_RS12045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FOC41_RS12070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FOC41_RS12080	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FOC41_RS12085	COG1088	dTDP-glucose 4,6-dehydratase activity
FOC41_RS12090	COG1575	Belongs to the MenA family. Type 1 subfamily
FOC41_RS12095	COG1408	metallophosphoesterase
FOC41_RS12100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOC41_RS12105	COG0194	GDP metabolic process
FOC41_RS12125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOC41_RS12130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOC41_RS12140	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOC41_RS12145	COG0750	zinc metalloprotease
FOC41_RS12160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC41_RS12170	COG2814	Major facilitator Superfamily
FOC41_RS12180	COG1328	CTP reductase activity
FOC41_RS12200	COG1538	Outer membrane efflux protein
FOC41_RS12220	COG1629	transport
FOC41_RS12240	COG2814	Major facilitator Superfamily
FOC41_RS12265	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS12280	COG0561	phosphatase activity
FOC41_RS12285	COG4771	TonB-dependent receptor
FOC41_RS12310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOC41_RS12330	COG3550	peptidyl-serine autophosphorylation
FOC41_RS12395	COG1505	serine-type exopeptidase activity
FOC41_RS12410	COG3119	arylsulfatase activity
FOC41_RS12415	COG3119	arylsulfatase activity
FOC41_RS12425	COG0617	tRNA 3'-terminal CCA addition
FOC41_RS12440	COG0632	four-way junction helicase activity
FOC41_RS12445	COG0673	inositol 2-dehydrogenase activity
FOC41_RS12460	COG1272	protein, Hemolysin III
FOC41_RS12465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOC41_RS12470	COG1629	transport
FOC41_RS12470	COG4206	TonB-dependent receptor
FOC41_RS12475	COG1629	transport
FOC41_RS12485	COG2204	response regulator
FOC41_RS12490	COG0488	(ABC) transporter
FOC41_RS12530	COG1595	DNA-templated transcription, initiation
FOC41_RS12540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC41_RS12545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOC41_RS12555	COG1522	sequence-specific DNA binding
FOC41_RS12585	COG4771	TonB-dependent receptor
FOC41_RS12620	COG0811	peptide transport
FOC41_RS12630	COG0084	hydrolase, TatD family'
FOC41_RS12650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOC41_RS12655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOC41_RS12660	COG0205	6-phosphofructokinase activity
FOC41_RS12695	COG0372	Belongs to the citrate synthase family
FOC41_RS12705	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOC41_RS12710	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC41_RS12720	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOC41_RS12735	COG0028	Belongs to the TPP enzyme family
FOC41_RS12740	COG0129	dihydroxy-acid dehydratase activity
FOC41_RS12750	COG3681	Belongs to the UPF0597 family
FOC41_RS12770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOC41_RS12825	COG4206	TonB-dependent receptor
FOC41_RS12825	COG1629	transport
FOC41_RS12835	COG1595	DNA-templated transcription, initiation
FOC41_RS12840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC41_RS12840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC41_RS12845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FOC41_RS12850	COG0569	domain protein
FOC41_RS12850	COG2985	domain, Protein
FOC41_RS12865	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
FOC41_RS12870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FOC41_RS12905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOC41_RS12975	COG0702	epimerase
FOC41_RS12980	COG4771	TonB-dependent receptor
FOC41_RS12985	COG1940	carbohydrate kinase activity
FOC41_RS12995	COG2188	Transcriptional regulator
FOC41_RS13015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC41_RS13025	COG2207	Transcriptional regulator
FOC41_RS13025	COG1609	Transcriptional regulator
FOC41_RS13030	COG0534	Mate efflux family protein
FOC41_RS13035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOC41_RS13040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOC41_RS13045	COG0166	Belongs to the GPI family
FOC41_RS13060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOC41_RS13080	COG2502	aspartate--ammonia ligase
FOC41_RS13085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOC41_RS13100	COG3876	Protein conserved in bacteria
FOC41_RS13120	COG2315	Protein conserved in bacteria
FOC41_RS13125	COG2186	Transcriptional regulator
FOC41_RS13145	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS13155	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOC41_RS13160	COG0778	Nitroreductase
FOC41_RS13170	COG1640	4-alpha-glucanotransferase
FOC41_RS13190	COG1216	Glycosyl transferase, family 2
FOC41_RS13200	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC41_RS13205	COG1022	Amp-dependent synthetase and ligase
FOC41_RS13240	COG0359	binds to the 23S rRNA
FOC41_RS13245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOC41_RS13250	COG0360	Binds together with S18 to 16S ribosomal RNA
FOC41_RS13270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC41_RS13275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOC41_RS13315	COG2431	L-lysine efflux transmembrane transporter activity
FOC41_RS13355	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOC41_RS13375	COG2234	aminopeptidase activity
FOC41_RS13390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOC41_RS13395	COG0802	atpase or kinase
FOC41_RS13415	COG0714	Associated with various cellular activities
FOC41_RS13450	COG3118	belongs to the thioredoxin family
FOC41_RS13470	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS13475	COG1629	transport
FOC41_RS13475	COG4206	TonB-dependent receptor
FOC41_RS13490	COG0457	Tetratricopeptide repeat
FOC41_RS13495	COG2814	Major facilitator Superfamily
FOC41_RS13510	COG0688	phosphatidylethanolamine metabolic process
FOC41_RS13515	COG1183	phosphatidylcholine synthase activity
FOC41_RS13535	COG0792	nuclease activity
FOC41_RS13560	COG0534	Mate efflux family protein
FOC41_RS13565	COG0528	UMP kinase activity
FOC41_RS13580	COG3250	beta-galactosidase activity
FOC41_RS13590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS13595	COG4206	TonB-dependent receptor
FOC41_RS13595	COG1629	transport
FOC41_RS13600	COG0745	RESPONSE REGULATOR receiver
FOC41_RS13600	COG3292	Two component regulator propeller
FOC41_RS13600	COG2205	protein histidine kinase activity
FOC41_RS13610	COG0233	cytoplasmic translational termination
FOC41_RS13615	COG1162	GTPase activity
FOC41_RS13625	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOC41_RS13640	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC41_RS13640	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FOC41_RS13655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOC41_RS13670	COG1629	transport
FOC41_RS13670	COG4206	TonB-dependent receptor
FOC41_RS13675	COG4974	Belongs to the 'phage' integrase family
FOC41_RS13680	COG1629	transport
FOC41_RS13700	COG1629	transport
FOC41_RS13700	COG4206	TonB-dependent receptor
FOC41_RS13720	COG2095	MarC family integral membrane protein
FOC41_RS13735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC41_RS13745	COG1435	thymidine kinase activity
FOC41_RS13750	COG0628	permease
FOC41_RS13780	COG1830	Aldolase
FOC41_RS13785	COG0588	phosphoglycerate mutase activity
FOC41_RS13795	COG1595	DNA-templated transcription, initiation
FOC41_RS13800	COG0205	6-phosphofructokinase activity
FOC41_RS13805	COG0058	SHG alpha-glucan phosphorylase activity
FOC41_RS13810	COG0010	Belongs to the arginase family
FOC41_RS13815	COG4413	Urea transporter
FOC41_RS13820	COG1396	sequence-specific DNA binding
FOC41_RS13830	COG4771	TonB-dependent receptor
FOC41_RS13890	COG2076	Multidrug Resistance protein
FOC41_RS13905	COG0475	glutathione-regulated potassium exporter activity
FOC41_RS13905	COG0589	response to stress
FOC41_RS13930	COG2207	Transcriptional regulator
FOC41_RS13940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC41_RS13945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOC41_RS13960	COG0534	Mate efflux family protein
FOC41_RS13980	COG1522	sequence-specific DNA binding
FOC41_RS13995	COG0668	transmembrane transport
FOC41_RS14015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOC41_RS14020	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FOC41_RS14025	COG0460	homoserine dehydrogenase
FOC41_RS14025	COG0527	aspartate kinase activity
FOC41_RS14030	COG0252	asparaginase activity
FOC41_RS14035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FOC41_RS14040	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FOC41_RS14050	COG4771	TonB-dependent receptor
FOC41_RS14065	COG0826	peptidase U32
FOC41_RS14070	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOC41_RS14085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FOC41_RS14105	COG0519	Catalyzes the synthesis of GMP from XMP
FOC41_RS14110	COG5002	protein histidine kinase activity
FOC41_RS14115	COG2205	protein histidine kinase activity
FOC41_RS14125	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOC41_RS14130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FOC41_RS14135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOC41_RS14150	COG3387	PFAM Glycoside hydrolase 15-related
FOC41_RS14185	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS14215	COG4771	TonB-dependent receptor
FOC41_RS14230	COG0471	metal ion transport
FOC41_RS14235	COG0745	RESPONSE REGULATOR receiver
FOC41_RS14235	COG2205	protein histidine kinase activity
FOC41_RS14235	COG3292	Two component regulator propeller
FOC41_RS14235	COG0745	RESPONSE REGULATOR receiver
FOC41_RS14235	COG2205	protein histidine kinase activity
FOC41_RS14235	COG3292	Two component regulator propeller
FOC41_RS14245	COG5012	cobalamin binding
FOC41_RS14290	COG4771	TonB-dependent receptor
FOC41_RS14315	COG3537	Alpha-1,2-mannosidase
FOC41_RS14330	COG3250	beta-galactosidase activity
FOC41_RS14350	COG4771	TonB-dependent receptor
FOC41_RS14360	COG4771	TonB-dependent receptor
FOC41_RS14380	COG0616	signal peptide processing
FOC41_RS14385	COG1663	tetraacyldisaccharide 4'-kinase activity
FOC41_RS14390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOC41_RS14395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FOC41_RS14415	COG0513	Belongs to the DEAD box helicase family
FOC41_RS14420	COG2070	2-Nitropropane dioxygenase
FOC41_RS14425	COG0724	RNA recognition motif
FOC41_RS14445	COG3973	AAA domain
FOC41_RS14490	COG2204	response regulator
FOC41_RS14495	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC41_RS14515	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS14520	COG0737	Belongs to the 5'-nucleotidase family
FOC41_RS14525	COG0737	Belongs to the 5'-nucleotidase family
FOC41_RS14530	COG0335	large ribosomal subunit rRNA binding
FOC41_RS14540	COG1136	(ABC) transporter
FOC41_RS14545	COG0577	efflux transmembrane transporter activity
FOC41_RS14545	COG1136	(ABC) transporter
FOC41_RS14550	COG1136	(ABC) transporter
FOC41_RS14550	COG0577	efflux transmembrane transporter activity
FOC41_RS14565	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC41_RS14565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOC41_RS14575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOC41_RS14595	COG2996	Protein conserved in bacteria
FOC41_RS14600	COG0039	L-malate dehydrogenase activity
FOC41_RS14610	COG2217	Heavy metal translocating P-type atpase
FOC41_RS14620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOC41_RS14625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOC41_RS14630	COG0509	glycine decarboxylation via glycine cleavage system
FOC41_RS14645	COG0006	proline dipeptidase activity
FOC41_RS14650	COG3458	cephalosporin-C deacetylase activity
FOC41_RS14665	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOC41_RS14675	COG1773	rubredoxin
FOC41_RS14680	COG2205	protein histidine kinase activity
FOC41_RS14680	COG2198	Histidine kinase
FOC41_RS14680	COG0784	Response regulator, receiver
FOC41_RS14685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOC41_RS14690	COG1011	Hydrolase
FOC41_RS14695	COG0196	riboflavin kinase activity
FOC41_RS14700	COG1266	CAAX protease self-immunity
FOC41_RS14705	COG2166	iron-sulfur cluster assembly
FOC41_RS14710	COG2234	aminopeptidase activity
FOC41_RS14715	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOC41_RS14725	COG0280	phosphate acetyltransferase
FOC41_RS14730	COG3426	butyrate kinase activity
FOC41_RS14735	COG3537	Alpha-1,2-mannosidase
FOC41_RS14755	COG1185	polyribonucleotide nucleotidyltransferase activity
FOC41_RS14765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOC41_RS14785	COG0076	glutamate decarboxylase activity
FOC41_RS14790	COG2066	Belongs to the glutaminase family
FOC41_RS14800	COG0531	amino acid
FOC41_RS14805	COG2205	protein histidine kinase activity
FOC41_RS14805	COG0784	Response regulator, receiver
FOC41_RS14820	COG3345	alpha-galactosidase
FOC41_RS14855	COG4974	Belongs to the 'phage' integrase family
FOC41_RS14875	COG1131	(ABC) transporter
FOC41_RS14950	COG0667	Aldo Keto reductase
FOC41_RS14955	COG1696	Membrane protein involved in D-alanine export
FOC41_RS14990	COG1309	transcriptional regulator
FOC41_RS14995	COG2986	histidine ammonia-lyase
FOC41_RS15005	COG1228	amidohydrolase
FOC41_RS15015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FOC41_RS15025	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC41_RS15040	COG0203	ribosomal protein L17
FOC41_RS15045	COG0202	RNA polymerase activity
FOC41_RS15050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOC41_RS15055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOC41_RS15060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOC41_RS15065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOC41_RS15070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOC41_RS15085	COG0200	Binds to the 23S rRNA
FOC41_RS15090	COG1841	ribosomal large subunit assembly
FOC41_RS15095	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOC41_RS15100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOC41_RS15105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOC41_RS15110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOC41_RS15115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOC41_RS15120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOC41_RS15125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOC41_RS15130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOC41_RS15135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOC41_RS15140	COG0255	Belongs to the universal ribosomal protein uL29 family
FOC41_RS15145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOC41_RS15150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOC41_RS15155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOC41_RS15160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOC41_RS15165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOC41_RS15170	COG0089	rRNA binding
FOC41_RS15175	COG0088	Forms part of the polypeptide exit tunnel
FOC41_RS15180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOC41_RS15185	COG0051	transcription antitermination factor activity, RNA binding
FOC41_RS15190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOC41_RS15195	COG0049	tRNA binding
FOC41_RS15200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOC41_RS15210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOC41_RS15215	COG0085	RNA polymerase activity
FOC41_RS15220	COG0222	ribosome binding
FOC41_RS15225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOC41_RS15230	COG0081	regulation of translation
FOC41_RS15235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOC41_RS15245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOC41_RS15255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOC41_RS15285	COG4974	Belongs to the 'phage' integrase family
FOC41_RS15290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOC41_RS15295	COG0006	proline dipeptidase activity
FOC41_RS15300	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOC41_RS15310	COG3118	belongs to the thioredoxin family
FOC41_RS15320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOC41_RS15330	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOC41_RS15340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOC41_RS15380	COG1027	Aspartate ammonia-lyase
FOC41_RS15385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FOC41_RS15390	COG0252	asparaginase activity
FOC41_RS15405	COG2096	Adenosyltransferase
FOC41_RS15420	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOC41_RS15420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOC41_RS15435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC41_RS15460	COG0501	Belongs to the peptidase M48B family
FOC41_RS15495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS15500	COG2972	Histidine kinase
FOC41_RS15525	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOC41_RS15525	COG0662	Cupin 2, conserved barrel domain protein
FOC41_RS15530	COG0318	PFAM AMP-dependent synthetase and ligase
FOC41_RS15535	COG1396	sequence-specific DNA binding
FOC41_RS15540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOC41_RS15545	COG1217	gtp-binding protein TYPA
FOC41_RS15555	COG2059	Chromate
FOC41_RS15570	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FOC41_RS15575	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOC41_RS15610	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOC41_RS15615	COG5002	protein histidine kinase activity
FOC41_RS15615	COG2205	protein histidine kinase activity
FOC41_RS15615	COG0784	Response regulator, receiver
FOC41_RS15620	COG0793	Belongs to the peptidase S41A family
FOC41_RS15625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC41_RS15655	COG1629	transport
FOC41_RS15655	COG4206	TonB-dependent receptor
FOC41_RS15660	COG4977	sequence-specific DNA binding
FOC41_RS15660	COG1917	Cupin 2, conserved barrel domain protein
FOC41_RS15685	COG1040	competence protein
FOC41_RS15730	COG2610	gluconate transmembrane transporter activity
FOC41_RS15755	COG1629	transport
FOC41_RS15780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC41_RS15785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC41_RS15790	COG4771	TonB-dependent receptor
FOC41_RS15840	COG4771	TonB-dependent receptor
FOC41_RS15845	COG2205	protein histidine kinase activity
FOC41_RS15845	COG0745	RESPONSE REGULATOR receiver
FOC41_RS15845	COG3292	Two component regulator propeller
FOC41_RS15865	COG2816	NAD+ diphosphatase activity
FOC41_RS15910	COG0018	arginyl-trna synthetase
FOC41_RS15920	COG0705	Rhomboid family
FOC41_RS15935	COG0339	signal peptide processing
FOC41_RS15940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOC41_RS15950	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOC41_RS15950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOC41_RS15955	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOC41_RS15965	COG1629	transport
FOC41_RS15990	COG3250	beta-galactosidase activity
FOC41_RS15995	COG3458	cephalosporin-C deacetylase activity
FOC41_RS16000	COG3345	alpha-galactosidase
FOC41_RS16005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOC41_RS16025	COG1629	transport
FOC41_RS16045	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS16080	COG4771	TonB-dependent receptor
FOC41_RS16095	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOC41_RS16100	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOC41_RS16120	COG4974	Belongs to the 'phage' integrase family
FOC41_RS16135	COG0606	chelatase, subunit chli
FOC41_RS16140	COG2205	protein histidine kinase activity
FOC41_RS16160	COG3250	beta-galactosidase activity
FOC41_RS16195	COG4771	TonB-dependent receptor
FOC41_RS16205	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS16230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS16235	COG1629	transport
FOC41_RS16235	COG4206	TonB-dependent receptor
FOC41_RS16250	COG0673	inositol 2-dehydrogenase activity
FOC41_RS16260	COG0673	inositol 2-dehydrogenase activity
FOC41_RS16265	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS16270	COG3292	Two component regulator propeller
FOC41_RS16270	COG2205	protein histidine kinase activity
FOC41_RS16270	COG0745	RESPONSE REGULATOR receiver
FOC41_RS16280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC41_RS16280	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOC41_RS16295	COG3475	LICD family
FOC41_RS16310	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS16345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOC41_RS16350	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC41_RS16355	COG0545	Peptidyl-prolyl cis-trans isomerase
FOC41_RS16375	COG4974	Belongs to the 'phage' integrase family
FOC41_RS16415	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS16450	COG0561	phosphatase activity
FOC41_RS16515	COG4771	TonB-dependent receptor
FOC41_RS16520	COG0702	epimerase
FOC41_RS16530	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOC41_RS16535	COG3250	beta-galactosidase activity
FOC41_RS16540	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOC41_RS16550	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC41_RS16555	COG2211	Major facilitator Superfamily
FOC41_RS16560	COG3408	Glycogen debranching enzyme
FOC41_RS16585	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOC41_RS16590	COG0793	Belongs to the peptidase S41A family
FOC41_RS16590	COG3409	Peptidoglycan-binding domain 1 protein
FOC41_RS16595	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS16600	COG3250	beta-galactosidase activity
FOC41_RS16605	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS16610	COG3292	Two component regulator propeller
FOC41_RS16610	COG0745	RESPONSE REGULATOR receiver
FOC41_RS16610	COG2205	protein histidine kinase activity
FOC41_RS16615	COG3291	Pkd domain containing protein
FOC41_RS16625	COG0561	phosphatase activity
FOC41_RS16630	COG4771	TonB-dependent receptor
FOC41_RS16635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FOC41_RS16640	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS16645	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS16650	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS16695	COG0702	epimerase
FOC41_RS16700	COG4771	TonB-dependent receptor
FOC41_RS16705	COG3292	Two component regulator propeller
FOC41_RS16705	COG0745	RESPONSE REGULATOR receiver
FOC41_RS16705	COG2205	protein histidine kinase activity
FOC41_RS16720	COG0702	epimerase
FOC41_RS16725	COG4771	TonB-dependent receptor
FOC41_RS16735	COG3292	Two component regulator propeller
FOC41_RS16735	COG0745	RESPONSE REGULATOR receiver
FOC41_RS16735	COG2205	protein histidine kinase activity
FOC41_RS16755	COG1053	succinate dehydrogenase
FOC41_RS16760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOC41_RS16785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOC41_RS16810	COG2205	protein histidine kinase activity
FOC41_RS16810	COG3292	Two component regulator propeller
FOC41_RS16810	COG0745	RESPONSE REGULATOR receiver
FOC41_RS16835	COG3250	beta-galactosidase activity
FOC41_RS16840	COG3401	FG-GAP repeat protein
FOC41_RS16845	COG3250	beta-galactosidase activity
FOC41_RS16855	COG1629	transport
FOC41_RS16880	COG3250	beta-galactosidase activity
FOC41_RS16890	COG3401	FG-GAP repeat protein
FOC41_RS16895	COG0758	DNA mediated transformation
FOC41_RS16905	COG0826	peptidase U32
FOC41_RS16910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC41_RS16970	COG0557	exoribonuclease II activity
FOC41_RS16980	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS17005	COG4206	TonB-dependent receptor
FOC41_RS17005	COG1629	transport
FOC41_RS17015	COG5002	protein histidine kinase activity
FOC41_RS17025	COG1629	transport
FOC41_RS17025	COG4206	TonB-dependent receptor
FOC41_RS17040	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS17045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FOC41_RS17050	COG1917	Cupin 2, conserved barrel domain protein
FOC41_RS17060	COG4124	Belongs to the glycosyl hydrolase 26 family
FOC41_RS17080	COG0702	epimerase
FOC41_RS17085	COG4771	TonB-dependent receptor
FOC41_RS17090	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC41_RS17130	COG0702	epimerase
FOC41_RS17135	COG4771	TonB-dependent receptor
FOC41_RS17180	COG0745	RESPONSE REGULATOR receiver
FOC41_RS17180	COG2205	protein histidine kinase activity
FOC41_RS17180	COG3292	Two component regulator propeller
FOC41_RS17205	COG1629	transport
FOC41_RS17205	COG4206	TonB-dependent receptor
FOC41_RS17230	COG3119	arylsulfatase activity
FOC41_RS17240	COG2814	Major facilitator Superfamily
FOC41_RS17245	COG0464	growth
FOC41_RS17250	COG0012	GTP binding
FOC41_RS17255	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOC41_RS17260	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOC41_RS17265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOC41_RS17290	COG0222	ribosome binding
FOC41_RS17305	COG0697	spore germination
FOC41_RS17310	COG3250	beta-galactosidase activity
FOC41_RS17315	COG0495	leucyl-tRNA aminoacylation
FOC41_RS17320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC41_RS17325	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOC41_RS17330	COG1360	Flagellar Motor Protein
FOC41_RS17350	COG2205	protein histidine kinase activity
FOC41_RS17350	COG3292	Two component regulator propeller
FOC41_RS17350	COG0745	RESPONSE REGULATOR receiver
FOC41_RS17350	COG3292	Two component regulator propeller
FOC41_RS17350	COG2205	protein histidine kinase activity
FOC41_RS17350	COG0745	RESPONSE REGULATOR receiver
FOC41_RS17355	COG3537	Alpha-1,2-mannosidase
FOC41_RS17360	COG0702	epimerase
FOC41_RS17365	COG4206	TonB-dependent receptor
FOC41_RS17365	COG1629	transport
FOC41_RS17375	COG5434	Belongs to the glycosyl hydrolase 28 family
FOC41_RS17385	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FOC41_RS17415	COG1629	transport
FOC41_RS17415	COG4206	TonB-dependent receptor
FOC41_RS17445	COG0731	radical SAM domain protein
FOC41_RS17445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC41_RS17450	COG2198	Histidine kinase
FOC41_RS17450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC41_RS17450	COG0784	Response regulator, receiver
FOC41_RS17450	COG2205	protein histidine kinase activity
FOC41_RS17460	COG1629	transport
FOC41_RS17480	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS17515	COG0659	secondary active sulfate transmembrane transporter activity
FOC41_RS17520	COG1592	Rubrerythrin
FOC41_RS17525	COG2205	protein histidine kinase activity
FOC41_RS17525	COG0745	RESPONSE REGULATOR receiver
FOC41_RS17525	COG3292	Two component regulator propeller
FOC41_RS17540	COG4771	TonB-dependent receptor
FOC41_RS17555	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FOC41_RS17585	COG2027	D-alanyl-D-alanine carboxypeptidase
FOC41_RS17590	COG0427	acetyl-CoA hydrolase
FOC41_RS17600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOC41_RS17625	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOC41_RS17655	COG2177	Part of the ABC transporter FtsEX involved in
FOC41_RS17665	COG1968	undecaprenyl-diphosphatase activity
FOC41_RS17670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOC41_RS17675	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC41_RS17680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOC41_RS17690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOC41_RS17725	COG1611	Belongs to the LOG family
FOC41_RS17740	COG0594	ribonuclease P activity
FOC41_RS17745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOC41_RS17755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOC41_RS17765	COG2205	protein histidine kinase activity
FOC41_RS17765	COG2202	Pas domain
FOC41_RS17775	COG4206	TonB-dependent receptor
FOC41_RS17775	COG1629	transport
FOC41_RS17780	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOC41_RS17785	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS17825	COG0726	polysaccharide deacetylase
FOC41_RS17845	COG4771	TonB-dependent receptor
FOC41_RS17945	COG1121	(ABC) transporter
FOC41_RS17960	COG1238	metal cluster binding
FOC41_RS17975	COG0823	Involved in the tonB-independent uptake of proteins
FOC41_RS17975	COG1506	peptidase
FOC41_RS17985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC41_RS17985	COG0116	Belongs to the methyltransferase superfamily
FOC41_RS17990	COG1045	serine acetyltransferase
FOC41_RS18000	COG3279	Response regulator of the LytR AlgR family
FOC41_RS18010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC41_RS18010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOC41_RS18015	COG0142	geranyltranstransferase activity
FOC41_RS18030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC41_RS18035	COG1694	Mazg nucleotide pyrophosphohydrolase
FOC41_RS18040	COG1490	D-aminoacyl-tRNA deacylase activity
FOC41_RS18045	COG0322	excinuclease ABC activity
FOC41_RS18050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOC41_RS18055	COG0445	tRNA wobble uridine modification
FOC41_RS18080	COG4771	TonB-dependent receptor
FOC41_RS18120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOC41_RS18125	COG2715	membrane protein required for spore maturation
FOC41_RS18130	COG2255	four-way junction helicase activity
FOC41_RS18150	COG3591	Belongs to the peptidase S1B family
FOC41_RS18160	COG3408	Glycogen debranching enzyme
FOC41_RS18165	COG3292	Two component regulator propeller
FOC41_RS18165	COG2205	protein histidine kinase activity
FOC41_RS18165	COG0745	RESPONSE REGULATOR receiver
FOC41_RS18175	COG3250	beta-galactosidase activity
FOC41_RS18180	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS18190	COG2755	lipolytic protein G-D-S-L family
FOC41_RS18190	COG0657	acetylesterase activity
FOC41_RS18210	COG1629	transport
FOC41_RS18210	COG4206	TonB-dependent receptor
FOC41_RS18215	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS18255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOC41_RS18270	COG0612	Peptidase, M16
FOC41_RS18285	COG0584	glycerophosphoryl diester phosphodiesterase
FOC41_RS18305	COG1629	transport
FOC41_RS18335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC41_RS18340	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FOC41_RS18350	COG4771	TonB-dependent receptor
FOC41_RS18355	COG0702	epimerase
FOC41_RS18370	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS18415	COG0681	Belongs to the peptidase S26 family
FOC41_RS18425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOC41_RS18460	COG1215	transferase activity, transferring glycosyl groups
FOC41_RS18480	COG5492	domain, Protein
FOC41_RS18490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOC41_RS18500	COG0702	epimerase
FOC41_RS18505	COG4771	TonB-dependent receptor
FOC41_RS18510	COG3119	arylsulfatase activity
FOC41_RS18515	COG3292	Two component regulator propeller
FOC41_RS18515	COG0745	RESPONSE REGULATOR receiver
FOC41_RS18515	COG2205	protein histidine kinase activity
FOC41_RS18515	COG2205	protein histidine kinase activity
FOC41_RS18515	COG0745	RESPONSE REGULATOR receiver
FOC41_RS18515	COG3292	Two component regulator propeller
FOC41_RS18525	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC41_RS18530	COG1538	Outer membrane efflux protein
FOC41_RS18540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOC41_RS18545	COG3250	beta-galactosidase activity
FOC41_RS18595	COG1629	transport
FOC41_RS18600	COG0702	epimerase
FOC41_RS18605	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS18610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOC41_RS18620	COG3940	Belongs to the glycosyl hydrolase 43 family
FOC41_RS18640	COG0561	phosphatase activity
FOC41_RS18645	COG4771	TonB-dependent receptor
FOC41_RS18665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS18670	COG3119	arylsulfatase activity
FOC41_RS18675	COG5492	domain, Protein
FOC41_RS18680	COG0215	cysteine-tRNA ligase activity
FOC41_RS18700	COG0561	phosphatase activity
FOC41_RS18720	COG0482	sulfurtransferase activity
FOC41_RS18730	COG0205	6-phosphofructokinase activity
FOC41_RS18735	COG0571	ribonuclease III activity
FOC41_RS18740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC41_RS18745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC41_RS18750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOC41_RS18755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOC41_RS18790	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS18795	COG3475	LICD family
FOC41_RS18800	COG4750	Nucleotidyl transferase
FOC41_RS18815	COG1216	Glycosyl transferase, family 2
FOC41_RS18820	COG3754	Rhamnan synthesis protein F
FOC41_RS18825	COG1216	Glycosyl transferase, family 2
FOC41_RS18850	COG0463	Glycosyl transferase, family 2
FOC41_RS18855	COG1442	glycosyl transferase family 8
FOC41_RS18865	COG1216	Glycosyl transferase, family 2
FOC41_RS18905	COG1132	(ABC) transporter
FOC41_RS18915	COG0463	Glycosyl transferase, family 2
FOC41_RS18935	COG0328	RNA-DNA hybrid ribonuclease activity
FOC41_RS18935	COG3341	Caulimovirus viroplasmin
FOC41_RS18945	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOC41_RS18955	COG0326	Molecular chaperone. Has ATPase activity
FOC41_RS18965	COG1166	arginine decarboxylase activity
FOC41_RS18970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOC41_RS18975	COG1595	DNA-templated transcription, initiation
FOC41_RS19000	COG0779	Required for maturation of 30S ribosomal subunits
FOC41_RS19005	COG0195	Participates in both transcription termination and antitermination
FOC41_RS19010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOC41_RS19020	COG0719	Fe-S assembly protein
FOC41_RS19025	COG0396	ATPase activity
FOC41_RS19030	COG0719	Fe-S assembly protein
FOC41_RS19035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FOC41_RS19040	COG0393	Putative heavy-metal-binding
FOC41_RS19055	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOC41_RS19060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOC41_RS19080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOC41_RS19095	COG0187	DNA topoisomerase II activity
FOC41_RS19100	COG0268	Binds directly to 16S ribosomal RNA
FOC41_RS19150	COG1381	Involved in DNA repair and RecF pathway recombination
FOC41_RS19200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOC41_RS19215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOC41_RS19220	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOC41_RS19225	COG0772	Belongs to the SEDS family
FOC41_RS19230	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOC41_RS19235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOC41_RS19240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOC41_RS19255	COG0275	rRNA processing
FOC41_RS19260	COG2001	Belongs to the MraZ family
FOC41_RS19280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOC41_RS19285	COG0756	dUTP diphosphatase activity
FOC41_RS19300	COG4942	peptidase
FOC41_RS19305	COG3292	Two component regulator propeller
FOC41_RS19305	COG0745	RESPONSE REGULATOR receiver
FOC41_RS19305	COG2205	protein histidine kinase activity
FOC41_RS19315	COG3119	arylsulfatase activity
FOC41_RS19330	COG4771	TonB-dependent receptor
FOC41_RS19340	COG4206	TonB-dependent receptor
FOC41_RS19340	COG1629	transport
FOC41_RS19365	COG1629	transport
FOC41_RS19370	COG0702	epimerase
FOC41_RS19395	COG4771	TonB-dependent receptor
FOC41_RS19400	COG0702	epimerase
FOC41_RS19410	COG3119	arylsulfatase activity
FOC41_RS19430	COG3119	arylsulfatase activity
FOC41_RS19440	COG3119	arylsulfatase activity
FOC41_RS19445	COG3119	arylsulfatase activity
FOC41_RS19475	COG1629	transport
FOC41_RS19480	COG0561	phosphatase activity
FOC41_RS19515	COG3537	Alpha-1,2-mannosidase
FOC41_RS19560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC41_RS19565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOC41_RS19570	COG1022	Amp-dependent synthetase and ligase
FOC41_RS19575	COG0612	Peptidase, M16
FOC41_RS19580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOC41_RS19590	COG2954	triphosphatase activity
FOC41_RS19625	COG3591	Belongs to the peptidase S1B family
FOC41_RS19625	COG1864	DNA RNA non-specific endonuclease
FOC41_RS19655	COG0561	phosphatase activity
FOC41_RS19660	COG4771	TonB-dependent receptor
FOC41_RS19690	COG0673	inositol 2-dehydrogenase activity
FOC41_RS19700	COG0673	inositol 2-dehydrogenase activity
FOC41_RS19725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FOC41_RS19735	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS19755	COG1629	transport
FOC41_RS19765	COG1609	Transcriptional regulator
FOC41_RS19765	COG2207	Transcriptional regulator
FOC41_RS19775	COG1373	ATPase (AAA superfamily
FOC41_RS19780	COG0423	glycine-tRNA ligase activity
FOC41_RS19790	COG1609	Transcriptional regulator
FOC41_RS19805	COG0738	Major facilitator superfamily
FOC41_RS19810	COG1063	alcohol dehydrogenase
FOC41_RS19820	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS19825	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS19830	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS19840	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS19845	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS19850	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS19855	COG4771	TonB-dependent receptor
FOC41_RS19870	COG0702	epimerase
FOC41_RS19890	COG2382	esterase
FOC41_RS19895	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS19900	COG0745	RESPONSE REGULATOR receiver
FOC41_RS19900	COG3292	Two component regulator propeller
FOC41_RS19900	COG2205	protein histidine kinase activity
FOC41_RS19920	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FOC41_RS19935	COG2211	Major facilitator Superfamily
FOC41_RS19945	COG1215	transferase activity, transferring glycosyl groups
FOC41_RS19950	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOC41_RS20005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOC41_RS20010	COG0589	response to stress
FOC41_RS20010	COG0475	glutathione-regulated potassium exporter activity
FOC41_RS20015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOC41_RS20020	COG1136	(ABC) transporter
FOC41_RS20030	COG0733	neurotransmitter:sodium symporter activity
FOC41_RS20040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOC41_RS20045	COG0784	Response regulator, receiver
FOC41_RS20045	COG5002	protein histidine kinase activity
FOC41_RS20050	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOC41_RS20055	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FOC41_RS20075	COG1082	Xylose isomerase domain protein TIM barrel
FOC41_RS20085	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS20090	COG2205	protein histidine kinase activity
FOC41_RS20090	COG3292	Two component regulator propeller
FOC41_RS20090	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20130	COG1346	cytolysis
FOC41_RS20135	COG1380	Effector of murein hydrolase LrgA
FOC41_RS20140	COG0280	phosphate acetyltransferase
FOC41_RS20145	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOC41_RS20160	COG2003	Belongs to the UPF0758 family
FOC41_RS20165	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20165	COG2205	protein histidine kinase activity
FOC41_RS20165	COG3292	Two component regulator propeller
FOC41_RS20170	COG1629	transport
FOC41_RS20170	COG4206	TonB-dependent receptor
FOC41_RS20195	COG3250	beta-galactosidase activity
FOC41_RS20210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOC41_RS20225	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS20230	COG4206	TonB-dependent receptor
FOC41_RS20230	COG1629	transport
FOC41_RS20235	COG1082	Xylose isomerase domain protein TIM barrel
FOC41_RS20240	COG0366	Alpha amylase catalytic
FOC41_RS20250	COG1785	Belongs to the alkaline phosphatase family
FOC41_RS20255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOC41_RS20260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOC41_RS20265	COG0515	serine threonine protein kinase
FOC41_RS20265	COG2815	serine threonine protein kinase
FOC41_RS20270	COG0564	pseudouridine synthase activity
FOC41_RS20295	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOC41_RS20300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOC41_RS20315	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOC41_RS20320	COG0436	Aminotransferase
FOC41_RS20330	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FOC41_RS20345	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOC41_RS20350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOC41_RS20360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC41_RS20360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOC41_RS20365	COG2890	protein-(glutamine-N5) methyltransferase activity
FOC41_RS20375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOC41_RS20385	COG0165	Argininosuccinate lyase
FOC41_RS20410	COG1629	transport
FOC41_RS20410	COG4206	TonB-dependent receptor
FOC41_RS20440	COG3292	Two component regulator propeller
FOC41_RS20440	COG2205	protein histidine kinase activity
FOC41_RS20440	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20450	COG1595	DNA-templated transcription, initiation
FOC41_RS20455	COG1629	transport
FOC41_RS20475	COG3458	cephalosporin-C deacetylase activity
FOC41_RS20510	COG1629	transport
FOC41_RS20525	COG4677	pectinesterase activity
FOC41_RS20530	COG3292	Two component regulator propeller
FOC41_RS20530	COG2205	protein histidine kinase activity
FOC41_RS20530	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOC41_RS20545	COG1917	Cupin 2, conserved barrel domain protein
FOC41_RS20545	COG1396	sequence-specific DNA binding
FOC41_RS20555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOC41_RS20560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOC41_RS20565	COG0137	argininosuccinate synthase activity
FOC41_RS20575	COG1438	arginine binding
FOC41_RS20580	COG1070	Carbohydrate kinase
FOC41_RS20585	COG4806	L-rhamnose isomerase
FOC41_RS20595	COG0235	Class ii aldolase
FOC41_RS20600	COG1454	alcohol dehydrogenase
FOC41_RS20610	COG3292	Two component regulator propeller
FOC41_RS20610	COG2205	protein histidine kinase activity
FOC41_RS20610	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20615	COG4771	TonB-dependent receptor
FOC41_RS20620	COG0702	epimerase
FOC41_RS20650	COG1501	Belongs to the glycosyl hydrolase 31 family
FOC41_RS20655	COG3250	beta-galactosidase activity
FOC41_RS20680	COG0564	pseudouridine synthase activity
FOC41_RS20710	COG3537	Alpha-1,2-mannosidase
FOC41_RS20715	COG0745	RESPONSE REGULATOR receiver
FOC41_RS20715	COG3292	Two component regulator propeller
FOC41_RS20715	COG2205	protein histidine kinase activity
FOC41_RS20735	COG4771	TonB-dependent receptor
FOC41_RS20755	COG3119	arylsulfatase activity
FOC41_RS20760	COG2204	response regulator
FOC41_RS20765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC41_RS20765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOC41_RS20770	COG0612	Peptidase, M16
FOC41_RS20775	COG0534	Mate efflux family protein
FOC41_RS20780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOC41_RS20780	COG2205	protein histidine kinase activity
FOC41_RS20795	COG4771	TonB-dependent receptor
FOC41_RS20810	COG0612	Peptidase, M16
FOC41_RS20840	COG0488	(ABC) transporter
FOC41_RS20845	COG3590	peptidase
FOC41_RS20850	COG0138	bifunctional purine biosynthesis protein purh
FOC41_RS20875	COG0772	Belongs to the SEDS family
FOC41_RS20885	COG1774	PSP1 C-terminal conserved region
FOC41_RS20890	COG0470	DNA polymerase III
FOC41_RS20895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOC41_RS20900	COG2193	ferroxidase activity
FOC41_RS20960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOC41_RS20965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOC41_RS20970	COG1160	GTP binding
FOC41_RS20980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOC41_RS20985	COG1127	ABC transporter
FOC41_RS20990	COG0724	RNA recognition motif
FOC41_RS20995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOC41_RS21000	COG0740	serine-type endopeptidase activity
FOC41_RS21005	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOC41_RS21010	COG0514	ATP-dependent DNA helicase (RecQ)
FOC41_RS21015	COG0517	IMP dehydrogenase activity
FOC41_RS21015	COG0516	GMP reductase activity
FOC41_RS21030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC41_RS21045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOC41_RS21070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOC41_RS21080	COG3022	response to hydroperoxide
FOC41_RS21085	COG0110	maltose O-acetyltransferase activity
FOC41_RS21105	COG1187	pseudouridine synthase activity
FOC41_RS21110	COG0017	Asparaginyl-tRNA synthetase
FOC41_RS21120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS21125	COG0745	RESPONSE REGULATOR receiver
FOC41_RS21125	COG2205	protein histidine kinase activity
FOC41_RS21125	COG3292	Two component regulator propeller
FOC41_RS21155	COG4771	TonB-dependent receptor
FOC41_RS21160	COG0702	epimerase
FOC41_RS21165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOC41_RS21170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOC41_RS21175	COG0052	Belongs to the universal ribosomal protein uS2 family
FOC41_RS21180	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOC41_RS21185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC41_RS21195	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FOC41_RS21200	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOC41_RS21205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOC41_RS21220	COG0482	sulfurtransferase activity
FOC41_RS21230	COG1570	exodeoxyribonuclease VII activity
FOC41_RS21240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOC41_RS21250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOC41_RS21255	COG0489	protein tyrosine kinase activity
FOC41_RS21260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOC41_RS21300	COG0039	L-malate dehydrogenase activity
FOC41_RS21310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOC41_RS21315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOC41_RS21320	COG0811	peptide transport
FOC41_RS21325	COG0848	biopolymer transport protein
FOC41_RS21340	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOC41_RS21345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOC41_RS21350	COG0105	UTP biosynthetic process
FOC41_RS21355	COG0739	heme binding
FOC41_RS21370	COG0149	triose-phosphate isomerase activity
FOC41_RS21380	COG0302	gtp cyclohydrolase
FOC41_RS21385	COG0358	DNA primase activity
FOC41_RS21395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOC41_RS21415	COG0514	ATP-dependent DNA helicase (RecQ)
FOC41_RS21420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FOC41_RS21420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOC41_RS21475	COG1215	transferase activity, transferring glycosyl groups
FOC41_RS21480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC41_RS21495	COG0726	polysaccharide deacetylase
FOC41_RS21510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC41_RS21515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC41_RS21540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOC41_RS21545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOC41_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
FOC41_RS21565	COG4771	TonB-dependent receptor
FOC41_RS21575	COG0009	L-threonylcarbamoyladenylate synthase
FOC41_RS21585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOC41_RS21590	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOC41_RS21595	COG0658	competence protein
FOC41_RS21595	COG2333	competence protein COMEC
FOC41_RS21600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FOC41_RS21610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOC41_RS21625	COG4771	TonB-dependent receptor
FOC41_RS21635	COG3537	Alpha-1,2-mannosidase
FOC41_RS21640	COG3537	Alpha-1,2-mannosidase
FOC41_RS21650	COG3537	Alpha-1,2-mannosidase
FOC41_RS21655	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS21660	COG3279	Response regulator of the LytR AlgR family
FOC41_RS21665	COG3275	phosphorelay sensor kinase activity
FOC41_RS21680	COG0386	Belongs to the glutathione peroxidase family
FOC41_RS21690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOC41_RS21705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOC41_RS21720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOC41_RS21725	COG0742	ribosomal rna small subunit methyltransferase
FOC41_RS21740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC41_RS21765	COG4771	TonB-dependent receptor
FOC41_RS21775	COG3537	Alpha-1,2-mannosidase
FOC41_RS21780	COG3537	Alpha-1,2-mannosidase
FOC41_RS21800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOC41_RS21805	COG0739	heme binding
FOC41_RS21815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOC41_RS21820	COG1388	LysM domain
FOC41_RS21820	COG0741	lytic transglycosylase activity
FOC41_RS21830	COG1475	DNA binding
FOC41_RS21835	COG1192	Involved in chromosome partitioning
FOC41_RS21840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOC41_RS21845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC41_RS21855	COG0575	Belongs to the CDS family
FOC41_RS21860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOC41_RS21875	COG1196	nuclear chromosome segregation
FOC41_RS21880	COG2239	Acts as a magnesium transporter
FOC41_RS21885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOC41_RS21895	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC41_RS21970	COG0668	transmembrane transport
FOC41_RS21975	COG0662	Cupin 2, conserved barrel domain protein
FOC41_RS21975	COG2207	Transcriptional regulator
FOC41_RS22000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC41_RS22005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOC41_RS22010	COG0713	ATP synthesis coupled electron transport
FOC41_RS22025	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOC41_RS22030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC41_RS22030	COG0649	NAD binding
FOC41_RS22035	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC41_RS22040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOC41_RS22075	COG3250	beta-galactosidase activity
FOC41_RS22085	COG3250	beta-galactosidase activity
FOC41_RS22095	COG1629	transport
FOC41_RS22100	COG0702	epimerase
FOC41_RS22105	COG4771	TonB-dependent receptor
FOC41_RS22140	COG3537	Alpha-1,2-mannosidase
FOC41_RS22160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC41_RS22165	COG0569	domain protein
FOC41_RS22170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOC41_RS22180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOC41_RS22185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOC41_RS22190	COG0805	protein transport
FOC41_RS22200	COG2271	Major facilitator Superfamily
FOC41_RS22205	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FOC41_RS22210	COG3775	system Galactitol-specific IIC component
FOC41_RS22215	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS22225	COG2755	lipolytic protein G-D-S-L family
FOC41_RS22230	COG3292	Two component regulator propeller
FOC41_RS22230	COG2205	protein histidine kinase activity
FOC41_RS22230	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22260	COG0702	epimerase
FOC41_RS22265	COG4206	TonB-dependent receptor
FOC41_RS22265	COG1629	transport
FOC41_RS22275	COG3279	Response regulator of the LytR AlgR family
FOC41_RS22300	COG1629	transport
FOC41_RS22305	COG0702	epimerase
FOC41_RS22320	COG4677	pectinesterase activity
FOC41_RS22330	COG1472	Belongs to the glycosyl hydrolase 3 family
FOC41_RS22335	COG3507	Belongs to the glycosyl hydrolase 43 family
FOC41_RS22345	COG3292	Two component regulator propeller
FOC41_RS22345	COG2205	protein histidine kinase activity
FOC41_RS22345	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22350	COG1242	4 iron, 4 sulfur cluster binding
FOC41_RS22360	COG0363	glucosamine-6-phosphate deaminase activity
FOC41_RS22365	COG0657	acetylesterase activity
FOC41_RS22365	COG2755	lipolytic protein G-D-S-L family
FOC41_RS22370	COG0009	L-threonylcarbamoyladenylate synthase
FOC41_RS22380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FOC41_RS22385	COG0561	phosphatase activity
FOC41_RS22405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC41_RS22405	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC41_RS22410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC41_RS22410	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOC41_RS22425	COG4771	TonB-dependent receptor
FOC41_RS22430	COG0561	phosphatase activity
FOC41_RS22440	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FOC41_RS22465	COG2755	lipolytic protein G-D-S-L family
FOC41_RS22500	COG0702	epimerase
FOC41_RS22505	COG1629	transport
FOC41_RS22540	COG4771	TonB-dependent receptor
FOC41_RS22560	COG3401	FG-GAP repeat protein
FOC41_RS22570	COG2755	lipolytic protein G-D-S-L family
FOC41_RS22580	COG3401	FG-GAP repeat protein
FOC41_RS22590	COG3254	rhamnose metabolic process
FOC41_RS22595	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22595	COG2205	protein histidine kinase activity
FOC41_RS22595	COG3292	Two component regulator propeller
FOC41_RS22595	COG3292	Two component regulator propeller
FOC41_RS22595	COG2205	protein histidine kinase activity
FOC41_RS22595	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22600	COG2755	lipolytic protein G-D-S-L family
FOC41_RS22600	COG0657	acetylesterase activity
FOC41_RS22610	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS22630	COG4771	TonB-dependent receptor
FOC41_RS22635	COG0702	epimerase
FOC41_RS22650	COG1629	transport
FOC41_RS22730	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22730	COG3292	Two component regulator propeller
FOC41_RS22730	COG3292	Two component regulator propeller
FOC41_RS22730	COG2205	protein histidine kinase activity
FOC41_RS22730	COG0745	RESPONSE REGULATOR receiver
FOC41_RS22730	COG2205	protein histidine kinase activity
FOC41_RS22750	COG0546	phosphoglycolate phosphatase activity
FOC41_RS22790	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FOC41_RS22800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOC41_RS22805	COG1506	peptidase
FOC41_RS22805	COG0823	Involved in the tonB-independent uptake of proteins
FOC41_RS22820	COG1629	transport
FOC41_RS22825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC41_RS22840	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOC41_RS22840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOC41_RS22845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOC41_RS22850	COG1078	dGTPase activity
FOC41_RS22855	COG0284	orotidine-5'-phosphate decarboxylase activity
FOC41_RS22860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOC41_RS22865	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOC41_RS22885	COG1704	LemA family
FOC41_RS22900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOC41_RS22910	COG2226	methyltransferase
FOC41_RS22915	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOC41_RS22920	COG1702	phosphate starvation-inducible protein PhoH
FOC41_RS22940	COG2268	Band 7 protein
FOC41_RS23015	COG3292	Two component regulator propeller
FOC41_RS23015	COG2205	protein histidine kinase activity
FOC41_RS23015	COG0745	RESPONSE REGULATOR receiver
FOC41_RS23020	COG0101	tRNA pseudouridine synthase activity
FOC41_RS23040	COG3250	beta-galactosidase activity
FOC41_RS23045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FOC41_RS23050	COG0673	inositol 2-dehydrogenase activity
FOC41_RS23055	COG0673	inositol 2-dehydrogenase activity
FOC41_RS23070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOC41_RS23080	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOC41_RS23095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOC41_RS23100	COG0793	Belongs to the peptidase S41A family
FOC41_RS23105	COG2131	deaminase
FOC41_RS23115	COG0339	signal peptide processing
FOC41_RS23120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOC41_RS23125	COG1970	mechanosensitive ion channel activity
FOC41_RS23130	COG0519	Catalyzes the synthesis of GMP from XMP
FOC41_RS23130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOC41_RS23155	COG0297	glycogen (starch) synthase activity
FOC41_RS23170	COG0297	glycogen (starch) synthase activity
FOC41_RS23175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOC41_RS23180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOC41_RS23185	COG0543	2 iron, 2 sulfur cluster binding
FOC41_RS23190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOC41_RS23195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOC41_RS23200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOC41_RS23215	COG0791	NLP P60 protein
FOC41_RS23230	COG0612	Peptidase, M16
FOC41_RS23235	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOC41_RS23240	COG1597	lipid kinase activity
FOC41_RS23245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOC41_RS23250	COG5433	transposase activity
FOC41_RS23265	COG1136	(ABC) transporter
FOC41_RS23285	COG2211	Major facilitator Superfamily
FOC41_RS23295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOC41_RS23310	COG1674	ftsk spoiiie
FOC41_RS23320	COG0492	ferredoxin-NADP+ reductase activity
FOC41_RS23325	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FOC41_RS23330	COG3118	belongs to the thioredoxin family
FOC41_RS23365	COG1629	transport
FOC41_RS23365	COG4206	TonB-dependent receptor
FOC41_RS23405	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC41_RS23405	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC41_RS23415	COG1234	tRNA 3'-trailer cleavage
FOC41_RS23420	COG2989	Protein conserved in bacteria
FOC41_RS23440	COG3956	TIGRFAM MazG family protein
FOC41_RS23455	COG0525	valine-tRNA ligase activity
FOC41_RS23460	COG2198	Histidine kinase
FOC41_RS23460	COG0784	Response regulator, receiver
FOC41_RS23460	COG2205	protein histidine kinase activity
FOC41_RS23465	COG1595	DNA-templated transcription, initiation
FOC41_RS23475	COG1629	transport
FOC41_RS23490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS23495	COG1595	DNA-templated transcription, initiation
FOC41_RS23505	COG1629	transport
FOC41_RS23505	COG4206	TonB-dependent receptor
FOC41_RS23510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS23535	COG0653	protein targeting
FOC41_RS23540	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FOC41_RS23550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOC41_RS23570	COG1253	flavin adenine dinucleotide binding
FOC41_RS23575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOC41_RS23585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOC41_RS23595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOC41_RS23600	COG2204	response regulator
FOC41_RS23640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOC41_RS23640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOC41_RS23655	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FOC41_RS23660	COG0563	adenylate kinase activity
FOC41_RS23665	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOC41_RS23670	COG1496	oxidoreductase activity
FOC41_RS23680	COG0739	heme binding
FOC41_RS23685	COG2706	6-phosphogluconolactonase activity
FOC41_RS23750	COG1595	DNA-templated transcription, initiation
FOC41_RS23755	COG1629	transport
FOC41_RS23755	COG4206	TonB-dependent receptor
FOC41_RS23830	COG2048	Heterodisulfide reductase, subunit B
FOC41_RS23870	COG3142	Participates in the control of copper homeostasis
FOC41_RS23875	COG1418	mRNA catabolic process
FOC41_RS23905	COG1070	Carbohydrate kinase
FOC41_RS23910	COG1063	alcohol dehydrogenase
FOC41_RS23915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FOC41_RS23940	COG1333	cytochrome c biogenesis protein
FOC41_RS23940	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOC41_RS23970	COG4771	TonB-dependent receptor
FOC41_RS24005	COG0246	Mannitol dehydrogenase
FOC41_RS24015	COG1063	alcohol dehydrogenase
FOC41_RS24030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOC41_RS24035	COG2832	Protein of unknown function (DUF454)
FOC41_RS24045	COG0602	queuosine metabolic process
FOC41_RS24050	COG0247	lactate metabolic process
FOC41_RS24055	COG1139	Iron-sulfur cluster binding protein
FOC41_RS24065	COG0351	phosphomethylpyrimidine kinase
FOC41_RS24090	COG4589	Belongs to the CDS family
FOC41_RS24100	COG2304	oxidoreductase activity
FOC41_RS24110	COG1393	Belongs to the ArsC family
FOC41_RS24120	COG4771	TonB-dependent receptor
FOC41_RS24135	COG2233	PERMEase
FOC41_RS24140	COG1509	lysine 2,3-aminomutase activity
FOC41_RS24175	COG1285	pathogenesis
FOC41_RS24185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOC41_RS24190	COG1388	LysM domain
FOC41_RS24190	COG0741	lytic transglycosylase activity
FOC41_RS24230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC41_RS24240	COG0534	Mate efflux family protein
FOC41_RS24250	COG0564	pseudouridine synthase activity
FOC41_RS24280	COG0346	lactoylglutathione lyase activity
FOC41_RS24355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOC41_RS24370	COG2184	nucleotidyltransferase activity
FOC41_RS24375	COG0732	type I restriction modification DNA specificity domain
FOC41_RS24390	COG4974	Belongs to the 'phage' integrase family
FOC41_RS24395	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOC41_RS24400	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FOC41_RS24405	COG1063	alcohol dehydrogenase
FOC41_RS24420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOC41_RS24425	COG5002	protein histidine kinase activity
FOC41_RS24425	COG0784	Response regulator, receiver
FOC41_RS24430	COG0702	epimerase
FOC41_RS24440	COG4864	UPF0365 protein
FOC41_RS24455	COG0037	tRNA processing
FOC41_RS24465	COG0582	viral genome integration into host DNA
FOC41_RS24495	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOC41_RS24515	COG1477	protein flavinylation
FOC41_RS24520	COG1971	Probably functions as a manganese efflux pump
FOC41_RS24535	COG0463	Glycosyl transferase, family 2
FOC41_RS24555	COG0148	phosphopyruvate hydratase activity
FOC41_RS24565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOC41_RS24580	COG1082	Xylose isomerase domain protein TIM barrel
FOC41_RS24585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FOC41_RS24590	COG2195	Cleaves the N-terminal amino acid of tripeptides
FOC41_RS24595	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOC41_RS24600	COG4651	solute:proton antiporter activity
FOC41_RS24600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC41_RS24610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOC41_RS24615	COG0193	aminoacyl-tRNA hydrolase activity
FOC41_RS24620	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOC41_RS24630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOC41_RS24645	COG0237	dephospho-CoA kinase activity
FOC41_RS24660	COG0542	response to heat
FOC41_RS24670	COG0583	DNA-binding transcription factor activity
FOC41_RS24695	COG2855	membrane
FOC41_RS24700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOC41_RS24705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOC41_RS24725	COG0443	Heat shock 70 kDa protein
FOC41_RS24750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOC41_RS24750	COG4651	solute:proton antiporter activity
FOC41_RS24755	COG0306	phosphate transporter
FOC41_RS24765	COG0586	Pfam SNARE associated Golgi protein
FOC41_RS24820	COG0038	chloride channel
FOC41_RS24830	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FOC41_RS24845	COG1940	carbohydrate kinase activity
FOC41_RS24855	COG3119	arylsulfatase activity
FOC41_RS24865	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FOC41_RS24870	COG0702	epimerase
FOC41_RS24875	COG4771	TonB-dependent receptor
FOC41_RS24885	COG5434	Belongs to the glycosyl hydrolase 28 family
FOC41_RS24895	COG2205	protein histidine kinase activity
FOC41_RS24895	COG3292	Two component regulator propeller
FOC41_RS24895	COG0745	RESPONSE REGULATOR receiver
FOC41_RS24900	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FOC41_RS24905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOC41_RS24915	COG2843	Capsule synthesis protein
FOC41_RS24930	COG3250	beta-galactosidase activity
FOC41_RS24945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOC41_RS24950	COG1629	transport
FOC41_RS24950	COG4206	TonB-dependent receptor
FOC41_RS24960	COG0745	RESPONSE REGULATOR receiver
FOC41_RS24960	COG2205	protein histidine kinase activity
FOC41_RS24960	COG3292	Two component regulator propeller
FOC41_RS25040	COG1216	Glycosyl transferase, family 2
FOC41_RS25050	COG0438	transferase activity, transferring glycosyl groups
FOC41_RS25060	COG1215	transferase activity, transferring glycosyl groups
FOC41_RS25075	COG1760	l-serine dehydratase
FOC41_RS25080	COG0598	Magnesium transport protein CorA
FOC41_RS25085	COG1193	negative regulation of DNA recombination
FOC41_RS25120	COG0626	cystathionine gamma-synthase activity
FOC41_RS25135	COG2197	response regulator
FOC41_RS25140	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FOC41_RS25145	COG0456	acetyltransferase
FOC41_RS25155	COG3189	MarR family transcriptional regulator
FOC41_RS25160	COG0561	phosphatase activity
FOC41_RS25165	COG1169	isochorismate synthase
FOC41_RS25170	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FOC41_RS25175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FOC41_RS25180	COG4948	Mandelate Racemase Muconate Lactonizing
FOC41_RS25190	COG0668	transmembrane transport
FOC41_RS25195	COG1523	belongs to the glycosyl hydrolase 13 family
FOC41_RS25205	COG1191	sigma factor activity
FOC41_RS25210	COG0515	serine threonine protein kinase
FOC41_RS25210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOC41_RS25220	COG1629	transport
FOC41_RS25220	COG4206	TonB-dependent receptor
FOC41_RS25255	COG0783	Belongs to the Dps family
FOC41_RS25265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FOC41_RS25285	COG1595	DNA-templated transcription, initiation