locus-tag	class	description
BACSA_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BACSA_RS00025	COG2204	response regulator
BACSA_RS00050	COG0745	RESPONSE REGULATOR receiver
BACSA_RS00055	COG2205	protein histidine kinase activity
BACSA_RS00070	COG0251	oxidation-reduction process
BACSA_RS00080	COG0488	(ABC) transporter
BACSA_RS00110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BACSA_RS00115	COG1410	methionine synthase
BACSA_RS00115	COG0646	methionine synthase
BACSA_RS00120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BACSA_RS00125	COG1660	Displays ATPase and GTPase activities
BACSA_RS00150	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BACSA_RS00165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BACSA_RS00170	COG0126	phosphoglycerate kinase activity
BACSA_RS00195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BACSA_RS00205	COG0534	Mate efflux family protein
BACSA_RS00215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BACSA_RS00235	COG3876	Protein conserved in bacteria
BACSA_RS00255	COG2223	nitrite transmembrane transporter activity
BACSA_RS00260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BACSA_RS00275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BACSA_RS00280	COG2502	aspartate--ammonia ligase
BACSA_RS00285	COG4372	Transposase
BACSA_RS00315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACSA_RS00375	COG2244	polysaccharide biosynthetic process
BACSA_RS00380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BACSA_RS00385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BACSA_RS00480	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BACSA_RS00490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BACSA_RS00500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BACSA_RS00505	COG0793	Belongs to the peptidase S41A family
BACSA_RS00505	COG3409	Peptidoglycan-binding domain 1 protein
BACSA_RS00510	COG2131	deaminase
BACSA_RS00520	COG0339	signal peptide processing
BACSA_RS00535	COG1032	radical SAM domain protein
BACSA_RS00560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BACSA_RS00565	COG0372	Belongs to the citrate synthase family
BACSA_RS00570	COG0538	isocitrate dehydrogenase activity
BACSA_RS00575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BACSA_RS00585	COG0584	glycerophosphoryl diester phosphodiesterase
BACSA_RS00600	COG0702	epimerase
BACSA_RS00605	COG1629	transport
BACSA_RS00605	COG4206	TonB-dependent receptor
BACSA_RS00615	COG0702	epimerase
BACSA_RS00620	COG4206	TonB-dependent receptor
BACSA_RS00620	COG1629	transport
BACSA_RS00665	COG0673	inositol 2-dehydrogenase activity
BACSA_RS00700	COG0543	2 iron, 2 sulfur cluster binding
BACSA_RS00705	COG1757	Na H antiporter
BACSA_RS00715	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BACSA_RS00725	COG1704	LemA family
BACSA_RS00735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BACSA_RS00740	COG2226	methyltransferase
BACSA_RS00745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BACSA_RS00750	COG1702	phosphate starvation-inducible protein PhoH
BACSA_RS00760	COG0101	tRNA pseudouridine synthase activity
BACSA_RS00765	COG0490	domain, Protein
BACSA_RS00765	COG0471	metal ion transport
BACSA_RS00780	COG3275	phosphorelay sensor kinase activity
BACSA_RS00785	COG3279	Response regulator of the LytR AlgR family
BACSA_RS00795	COG0622	Phosphoesterase
BACSA_RS00800	COG2885	chlorophyll binding
BACSA_RS00815	COG3250	beta-galactosidase activity
BACSA_RS00830	COG0366	Alpha amylase catalytic
BACSA_RS00835	COG1082	Xylose isomerase domain protein TIM barrel
BACSA_RS00840	COG1629	transport
BACSA_RS00840	COG4206	TonB-dependent receptor
BACSA_RS00845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BACSA_RS00865	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACSA_RS00875	COG0295	cytidine deaminase activity
BACSA_RS00935	COG4535	Mg2 and Co2 transporter CorC
BACSA_RS00955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BACSA_RS00970	COG0653	protein targeting
BACSA_RS00975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACSA_RS00980	COG0166	Belongs to the GPI family
BACSA_RS00990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BACSA_RS00995	COG0318	PFAM AMP-dependent synthetase and ligase
BACSA_RS01005	COG1408	metallophosphoesterase
BACSA_RS01015	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BACSA_RS01020	COG0463	Glycosyl transferase, family 2
BACSA_RS01040	COG2211	Major facilitator Superfamily
BACSA_RS01060	COG1136	(ABC) transporter
BACSA_RS01075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BACSA_RS01090	COG0356	it plays a direct role in the translocation of protons across the membrane
BACSA_RS01095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BACSA_RS01100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BACSA_RS01105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BACSA_RS01110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BACSA_RS01115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BACSA_RS01120	COG0513	Belongs to the DEAD box helicase family
BACSA_RS01125	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BACSA_RS01130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BACSA_RS01145	COG1739	Uncharacterized protein family UPF0029
BACSA_RS01155	COG1629	transport
BACSA_RS01205	COG1882	Formate acetyltransferase
BACSA_RS01210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BACSA_RS01225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACSA_RS01235	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BACSA_RS01270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BACSA_RS01280	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BACSA_RS01285	COG1523	belongs to the glycosyl hydrolase 13 family
BACSA_RS01290	COG1119	ATPase activity
BACSA_RS01305	COG0564	pseudouridine synthase activity
BACSA_RS01310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BACSA_RS01325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BACSA_RS01335	COG0754	glutathionylspermidine amidase activity
BACSA_RS01350	COG0297	glycogen (starch) synthase activity
BACSA_RS01355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BACSA_RS01360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BACSA_RS01375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BACSA_RS01375	COG0574	Belongs to the PEP-utilizing enzyme family
BACSA_RS01435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BACSA_RS01440	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BACSA_RS01495	COG1373	ATPase (AAA superfamily
BACSA_RS01515	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BACSA_RS01525	COG0009	L-threonylcarbamoyladenylate synthase
BACSA_RS01535	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BACSA_RS01545	COG1191	sigma factor activity
BACSA_RS01555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BACSA_RS01570	COG1640	4-alpha-glucanotransferase
BACSA_RS01575	COG1523	belongs to the glycosyl hydrolase 13 family
BACSA_RS01590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BACSA_RS01635	COG0582	viral genome integration into host DNA
BACSA_RS01675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BACSA_RS01715	COG0758	DNA mediated transformation
BACSA_RS01810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BACSA_RS01825	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BACSA_RS01865	COG0629	single-stranded DNA binding
BACSA_RS01905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BACSA_RS02045	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACSA_RS02110	COG0739	heme binding
BACSA_RS02120	COG1373	ATPase (AAA superfamily
BACSA_RS02155	COG0629	single-stranded DNA binding
BACSA_RS02170	COG1475	DNA binding
BACSA_RS02440	COG4974	Belongs to the 'phage' integrase family
BACSA_RS02445	COG1309	transcriptional regulator
BACSA_RS02575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BACSA_RS02600	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BACSA_RS02665	COG3328	transposase activity
BACSA_RS02680	COG4974	Belongs to the 'phage' integrase family
BACSA_RS02690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BACSA_RS02695	COG1956	GAF domain-containing protein
BACSA_RS02705	COG4864	UPF0365 protein
BACSA_RS02720	COG0037	tRNA processing
BACSA_RS02770	COG3617	BRO family, N-terminal domain
BACSA_RS02790	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACSA_RS02790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACSA_RS02800	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BACSA_RS02805	COG2985	domain, Protein
BACSA_RS02805	COG0569	domain protein
BACSA_RS02810	COG1011	Hydrolase
BACSA_RS02815	COG1506	peptidase
BACSA_RS02815	COG0823	Involved in the tonB-independent uptake of proteins
BACSA_RS02830	COG1979	alcohol dehydrogenase
BACSA_RS02855	COG0343	queuine tRNA-ribosyltransferase activity
BACSA_RS02860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BACSA_RS02865	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BACSA_RS02875	COG0156	8-amino-7-oxononanoate synthase activity
BACSA_RS02885	COG0561	phosphatase activity
BACSA_RS02890	COG1285	pathogenesis
BACSA_RS02900	COG0024	Methionine aminopeptidase
BACSA_RS02905	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BACSA_RS02910	COG1546	Belongs to the CinA family
BACSA_RS02910	COG1058	Belongs to the CinA family
BACSA_RS02915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BACSA_RS02920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BACSA_RS02925	COG0552	protein localization to endoplasmic reticulum
BACSA_RS02930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACSA_RS02935	COG0776	regulation of translation
BACSA_RS02945	COG0714	Associated with various cellular activities
BACSA_RS02960	COG2304	oxidoreductase activity
BACSA_RS02985	COG0671	phosphoesterase, PA-phosphatase related
BACSA_RS03000	COG0393	Putative heavy-metal-binding
BACSA_RS03055	COG4372	Transposase
BACSA_RS03075	COG1752	Esterase of the alpha-beta hydrolase superfamily
BACSA_RS03085	COG0542	response to heat
BACSA_RS03090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BACSA_RS03100	COG0442	prolyl-tRNA aminoacylation
BACSA_RS03110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BACSA_RS03115	COG2731	YhcH YjgK YiaL family protein
BACSA_RS03125	COG0483	inositol monophosphate 1-phosphatase activity
BACSA_RS03180	COG0560	Phosphoserine phosphatase
BACSA_RS03180	COG3830	Belongs to the UPF0237 family
BACSA_RS03185	COG0513	Belongs to the DEAD box helicase family
BACSA_RS03210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BACSA_RS03220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BACSA_RS03225	COG2431	L-lysine efflux transmembrane transporter activity
BACSA_RS03240	COG0336	Belongs to the RNA methyltransferase TrmD family
BACSA_RS03245	COG0167	dihydroorotate dehydrogenase activity
BACSA_RS03250	COG0543	2 iron, 2 sulfur cluster binding
BACSA_RS03275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BACSA_RS03285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BACSA_RS03300	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BACSA_RS03320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BACSA_RS03320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BACSA_RS03325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BACSA_RS03330	COG0357	Ribosomal RNA small subunit methyltransferase G
BACSA_RS03340	COG0321	lipoyl(octanoyl) transferase activity
BACSA_RS03355	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BACSA_RS03360	COG0540	Belongs to the ATCase OTCase family
BACSA_RS03365	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BACSA_RS03380	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BACSA_RS03385	COG3047	cAMP biosynthetic process
BACSA_RS03385	COG2885	chlorophyll binding
BACSA_RS03405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BACSA_RS03415	COG0739	heme binding
BACSA_RS03420	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BACSA_RS03435	COG0492	ferredoxin-NADP+ reductase activity
BACSA_RS03440	COG0612	Peptidase, M16
BACSA_RS03450	COG1131	(ABC) transporter
BACSA_RS03455	COG0791	NLP P60 protein
BACSA_RS03465	COG0436	Aminotransferase
BACSA_RS03480	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BACSA_RS03495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BACSA_RS03500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BACSA_RS03515	COG1674	ftsk spoiiie
BACSA_RS03540	COG1629	transport
BACSA_RS03540	COG4206	TonB-dependent receptor
BACSA_RS03555	COG1082	Xylose isomerase domain protein TIM barrel
BACSA_RS03560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACSA_RS03570	COG0745	RESPONSE REGULATOR receiver
BACSA_RS03575	COG2205	protein histidine kinase activity
BACSA_RS03590	COG0246	Mannitol dehydrogenase
BACSA_RS03595	COG1904	glucuronate isomerase
BACSA_RS03600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BACSA_RS03605	COG4372	Transposase
BACSA_RS03635	COG2160	L-arabinose isomerase activity
BACSA_RS03645	COG0494	nUDIX hydrolase
BACSA_RS03660	COG0351	phosphomethylpyrimidine kinase
BACSA_RS03680	COG0110	maltose O-acetyltransferase activity
BACSA_RS03685	COG1073	alpha beta
BACSA_RS03695	COG1064	alcohol dehydrogenase
BACSA_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS03730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BACSA_RS03735	COG4607	ABC-type enterochelin transport system periplasmic component
BACSA_RS03750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACSA_RS03760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BACSA_RS03765	COG1597	lipid kinase activity
BACSA_RS03770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BACSA_RS03790	COG0217	transcriptional regulatory protein
BACSA_RS03805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BACSA_RS03815	COG0842	Transport permease protein
BACSA_RS03820	COG0842	Transport permease protein
BACSA_RS03830	COG1131	(ABC) transporter
BACSA_RS03835	COG1131	(ABC) transporter
BACSA_RS03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS03865	COG0504	CTP synthase activity
BACSA_RS03870	COG0706	membrane insertase activity
BACSA_RS03890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BACSA_RS03915	COG0745	RESPONSE REGULATOR receiver
BACSA_RS03915	COG2205	protein histidine kinase activity
BACSA_RS03915	COG3292	Two component regulator propeller
BACSA_RS03920	COG2059	Chromate
BACSA_RS03960	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BACSA_RS03965	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BACSA_RS03975	COG1805	sodium ion transport
BACSA_RS04010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BACSA_RS04015	COG0105	UTP biosynthetic process
BACSA_RS04030	COG0738	Major facilitator superfamily
BACSA_RS04065	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BACSA_RS04075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BACSA_RS04095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BACSA_RS04105	COG0439	Biotin carboxylase
BACSA_RS04110	COG1215	transferase activity, transferring glycosyl groups
BACSA_RS04130	COG1063	alcohol dehydrogenase
BACSA_RS04170	COG4771	TonB-dependent receptor
BACSA_RS04180	COG3537	Alpha-1,2-mannosidase
BACSA_RS04190	COG3537	Alpha-1,2-mannosidase
BACSA_RS04195	COG3537	Alpha-1,2-mannosidase
BACSA_RS04205	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BACSA_RS04210	COG3537	Alpha-1,2-mannosidase
BACSA_RS04215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BACSA_RS04230	COG0028	Belongs to the TPP enzyme family
BACSA_RS04235	COG0129	dihydroxy-acid dehydratase activity
BACSA_RS04260	COG0546	phosphoglycolate phosphatase activity
BACSA_RS04265	COG0110	maltose O-acetyltransferase activity
BACSA_RS04270	COG2207	Transcriptional regulator
BACSA_RS04275	COG1047	Peptidyl-prolyl cis-trans
BACSA_RS04285	COG0305	Participates in initiation and elongation during chromosome replication
BACSA_RS04290	COG2816	NAD+ diphosphatase activity
BACSA_RS04295	COG2183	response to ionizing radiation
BACSA_RS04310	COG0484	heat shock protein binding
BACSA_RS04315	COG0737	Belongs to the 5'-nucleotidase family
BACSA_RS04320	COG1408	metallophosphoesterase
BACSA_RS04345	COG3279	Response regulator of the LytR AlgR family
BACSA_RS04350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BACSA_RS04405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BACSA_RS04420	COG4690	dipeptidase activity
BACSA_RS04430	COG2855	membrane
BACSA_RS04435	COG1966	Carbon starvation protein
BACSA_RS04445	COG0542	response to heat
BACSA_RS04450	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS04455	COG3250	beta-galactosidase activity
BACSA_RS04460	COG1501	Belongs to the glycosyl hydrolase 31 family
BACSA_RS04465	COG0745	RESPONSE REGULATOR receiver
BACSA_RS04465	COG2205	protein histidine kinase activity
BACSA_RS04465	COG3292	Two component regulator propeller
BACSA_RS04480	COG5297	Belongs to the glycosyl hydrolase family 6
BACSA_RS04480	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BACSA_RS04495	COG1629	transport
BACSA_RS04500	COG2755	lipolytic protein G-D-S-L family
BACSA_RS04500	COG0657	acetylesterase activity
BACSA_RS04505	COG3507	Belongs to the glycosyl hydrolase 43 family
BACSA_RS04510	COG2755	lipolytic protein G-D-S-L family
BACSA_RS04510	COG0657	acetylesterase activity
BACSA_RS04515	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS04520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BACSA_RS04525	COG0564	pseudouridine synthase activity
BACSA_RS04540	COG3263	regulation of cellular component size
BACSA_RS04545	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BACSA_RS04555	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BACSA_RS04575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BACSA_RS04580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BACSA_RS04595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BACSA_RS04615	COG0488	(ABC) transporter
BACSA_RS04620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BACSA_RS04625	COG0484	heat shock protein binding
BACSA_RS04650	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BACSA_RS04665	COG0436	Aminotransferase
BACSA_RS04685	COG4372	Transposase
BACSA_RS04725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BACSA_RS04745	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BACSA_RS04750	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BACSA_RS04755	COG0107	imidazoleglycerol-phosphate synthase activity
BACSA_RS04760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BACSA_RS04760	COG0140	phosphoribosyl-ATP diphosphatase activity
BACSA_RS04765	COG2884	Cell division ATP-binding protein ftsE
BACSA_RS04770	COG0527	aspartate kinase activity
BACSA_RS04775	COG0019	diaminopimelate decarboxylase activity
BACSA_RS04780	COG0525	valine-tRNA ligase activity
BACSA_RS04790	COG0656	L-ascorbic acid biosynthetic process
BACSA_RS04820	COG0110	maltose O-acetyltransferase activity
BACSA_RS04840	COG3409	Peptidoglycan-binding domain 1 protein
BACSA_RS04840	COG0793	Belongs to the peptidase S41A family
BACSA_RS04850	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BACSA_RS04850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BACSA_RS04860	COG1773	rubredoxin
BACSA_RS04860	COG1592	Rubrerythrin
BACSA_RS04875	COG0539	negative regulation of cytoplasmic translation
BACSA_RS04885	COG4771	TonB-dependent receptor
BACSA_RS04895	COG0523	cobalamin synthesis protein
BACSA_RS04900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BACSA_RS04910	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS04915	COG1082	Xylose isomerase domain protein TIM barrel
BACSA_RS04920	COG4677	pectinesterase activity
BACSA_RS04930	COG2264	protein methyltransferase activity
BACSA_RS04940	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BACSA_RS04950	COG3757	hydrolase, family 25
BACSA_RS04950	COG3409	Peptidoglycan-binding domain 1 protein
BACSA_RS04980	COG0778	Nitroreductase
BACSA_RS04985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BACSA_RS04985	COG0321	lipoyl(octanoyl) transferase activity
BACSA_RS04990	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BACSA_RS05000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BACSA_RS05030	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BACSA_RS05040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACSA_RS05095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BACSA_RS05100	COG0360	Binds together with S18 to 16S ribosomal RNA
BACSA_RS05120	COG1757	Na H antiporter
BACSA_RS05170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BACSA_RS05185	COG1678	Uncharacterized ACR, COG1678
BACSA_RS05195	COG4974	Belongs to the 'phage' integrase family
BACSA_RS05250	COG2433	Pfam Transposase IS66
BACSA_RS05265	COG3209	COG3209 Rhs family protein
BACSA_RS05310	COG0551	DNA topoisomerase type I activity
BACSA_RS05310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BACSA_RS05330	COG0784	Response regulator, receiver
BACSA_RS05330	COG2198	Histidine kinase
BACSA_RS05330	COG5002	protein histidine kinase activity
BACSA_RS05340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BACSA_RS05375	COG3209	COG3209 Rhs family protein
BACSA_RS05405	COG0542	response to heat
BACSA_RS05560	COG1192	Involved in chromosome partitioning
BACSA_RS05580	COG1122	ATPase activity
BACSA_RS05785	COG4974	Belongs to the 'phage' integrase family
BACSA_RS05825	COG0210	DNA helicase
BACSA_RS05845	COG4974	Belongs to the 'phage' integrase family
BACSA_RS05920	COG4372	Transposase
BACSA_RS05955	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BACSA_RS05980	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BACSA_RS06010	COG0562	UDP-galactopyranose mutase
BACSA_RS06015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACSA_RS06020	COG0438	transferase activity, transferring glycosyl groups
BACSA_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS06145	COG0667	Aldo Keto reductase
BACSA_RS06205	COG1193	negative regulation of DNA recombination
BACSA_RS06210	COG1760	l-serine dehydratase
BACSA_RS06220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BACSA_RS06225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BACSA_RS06235	COG0237	dephospho-CoA kinase activity
BACSA_RS06245	COG1862	Preprotein translocase
BACSA_RS06250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BACSA_RS06260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BACSA_RS06265	COG0193	aminoacyl-tRNA hydrolase activity
BACSA_RS06270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BACSA_RS06280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BACSA_RS06280	COG4651	solute:proton antiporter activity
BACSA_RS06295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BACSA_RS06295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BACSA_RS06300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BACSA_RS06305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BACSA_RS06315	COG1690	Belongs to the RtcB family
BACSA_RS06380	COG3620	sequence-specific DNA binding
BACSA_RS06385	COG0590	tRNA wobble adenosine to inosine editing
BACSA_RS06395	COG0792	nuclease activity
BACSA_RS06405	COG0534	Mate efflux family protein
BACSA_RS06415	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BACSA_RS06425	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BACSA_RS06435	COG2382	esterase
BACSA_RS06460	COG0592	DNA-directed DNA polymerase activity
BACSA_RS06475	COG0497	DNA recombination
BACSA_RS06480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BACSA_RS06490	COG1234	tRNA 3'-trailer cleavage
BACSA_RS06520	COG0514	ATP-dependent DNA helicase (RecQ)
BACSA_RS06540	COG4771	TonB-dependent receptor
BACSA_RS06550	COG0826	peptidase U32
BACSA_RS06555	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BACSA_RS06560	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BACSA_RS06610	COG1253	flavin adenine dinucleotide binding
BACSA_RS06615	COG2197	response regulator
BACSA_RS06625	COG3385	transposase activity
BACSA_RS06630	COG1538	Outer membrane efflux protein
BACSA_RS06650	COG3385	transposase activity
BACSA_RS06660	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BACSA_RS06665	COG1333	cytochrome c biogenesis protein
BACSA_RS06665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BACSA_RS06675	COG3487	Iron-regulated protein
BACSA_RS06680	COG1730	sister chromatid segregation
BACSA_RS06700	COG0463	Glycosyl transferase, family 2
BACSA_RS06715	COG1971	Probably functions as a manganese efflux pump
BACSA_RS06720	COG1477	protein flavinylation
BACSA_RS06730	COG0657	acetylesterase activity
BACSA_RS06730	COG2755	lipolytic protein G-D-S-L family
BACSA_RS06745	COG4372	Transposase
BACSA_RS06775	COG0515	serine threonine protein kinase
BACSA_RS06790	COG0228	four-way junction DNA binding
BACSA_RS06800	COG1864	DNA RNA non-specific endonuclease
BACSA_RS06800	COG3591	Belongs to the peptidase S1B family
BACSA_RS06825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BACSA_RS06840	COG1695	Transcriptional regulator
BACSA_RS06855	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACSA_RS06870	COG3118	belongs to the thioredoxin family
BACSA_RS06875	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BACSA_RS06880	COG0572	uridine kinase
BACSA_RS06885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BACSA_RS06890	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BACSA_RS06900	COG0233	cytoplasmic translational termination
BACSA_RS06905	COG1162	GTPase activity
BACSA_RS06910	COG2271	Major facilitator Superfamily
BACSA_RS06915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BACSA_RS06920	COG0470	DNA polymerase III
BACSA_RS06925	COG1774	PSP1 C-terminal conserved region
BACSA_RS06935	COG0772	Belongs to the SEDS family
BACSA_RS06940	COG0768	penicillin binding
BACSA_RS06960	COG0138	bifunctional purine biosynthesis protein purh
BACSA_RS06975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BACSA_RS06980	COG0612	Peptidase, M16
BACSA_RS06985	COG0534	Mate efflux family protein
BACSA_RS06990	COG0784	Response regulator, receiver
BACSA_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BACSA_RS06990	COG2198	Histidine kinase
BACSA_RS06990	COG2205	protein histidine kinase activity
BACSA_RS06995	COG0584	glycerophosphoryl diester phosphodiesterase
BACSA_RS07000	COG0528	UMP kinase activity
BACSA_RS07005	COG0588	phosphoglycerate mutase activity
BACSA_RS07010	COG0488	(ABC) transporter
BACSA_RS07020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BACSA_RS07025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACSA_RS07030	COG0534	Mate efflux family protein
BACSA_RS07035	COG1914	H( )-stimulated, divalent metal cation uptake system
BACSA_RS07055	COG3345	alpha-galactosidase
BACSA_RS07080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BACSA_RS07090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BACSA_RS07100	COG0598	Magnesium transport protein CorA
BACSA_RS07105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BACSA_RS07110	COG0427	acetyl-CoA hydrolase
BACSA_RS07115	COG3104	oligopeptide transport
BACSA_RS07120	COG1929	Belongs to the glycerate kinase type-1 family
BACSA_RS07125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BACSA_RS07140	COG3885	ferrous iron binding
BACSA_RS07140	COG2078	PFAM AMMECR1 domain protein
BACSA_RS07155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACSA_RS07175	COG1120	ATPase activity
BACSA_RS07190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BACSA_RS07190	COG0519	Catalyzes the synthesis of GMP from XMP
BACSA_RS07205	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BACSA_RS07220	COG0564	pseudouridine synthase activity
BACSA_RS07225	COG1181	Belongs to the D-alanine--D-alanine ligase family
BACSA_RS07240	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BACSA_RS07245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BACSA_RS07250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BACSA_RS07265	COG1388	LysM domain
BACSA_RS07265	COG0741	lytic transglycosylase activity
BACSA_RS07270	COG1214	PFAM Peptidase M22, glycoprotease
BACSA_RS07280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BACSA_RS07285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BACSA_RS07295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BACSA_RS07305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BACSA_RS07310	COG1506	peptidase
BACSA_RS07310	COG0823	Involved in the tonB-independent uptake of proteins
BACSA_RS07320	COG1397	ADP-ribosylglycohydrolase
BACSA_RS07380	COG0697	spore germination
BACSA_RS07385	COG0641	radical SAM
BACSA_RS07395	COG3119	arylsulfatase activity
BACSA_RS07400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BACSA_RS07405	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BACSA_RS07425	COG0799	negative regulation of ribosome biogenesis
BACSA_RS07430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BACSA_RS07440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACSA_RS07445	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BACSA_RS07450	COG1192	Involved in chromosome partitioning
BACSA_RS07455	COG1475	DNA binding
BACSA_RS07465	COG1388	LysM domain
BACSA_RS07465	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACSA_RS07470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BACSA_RS07480	COG0739	heme binding
BACSA_RS07485	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BACSA_RS07490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BACSA_RS07500	COG0446	pyridine nucleotide-disulphide oxidoreductase
BACSA_RS07520	COG4771	TonB-dependent receptor
BACSA_RS07525	COG0702	epimerase
BACSA_RS07535	COG3250	beta-galactosidase activity
BACSA_RS07540	COG2205	protein histidine kinase activity
BACSA_RS07540	COG3292	Two component regulator propeller
BACSA_RS07540	COG0745	RESPONSE REGULATOR receiver
BACSA_RS07555	COG3956	TIGRFAM MazG family protein
BACSA_RS07565	COG4771	TonB-dependent receptor
BACSA_RS07575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BACSA_RS07595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BACSA_RS07600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BACSA_RS07615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACSA_RS07620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BACSA_RS07665	COG3292	Two component regulator propeller
BACSA_RS07665	COG2205	protein histidine kinase activity
BACSA_RS07665	COG0745	RESPONSE REGULATOR receiver
BACSA_RS07665	COG2205	protein histidine kinase activity
BACSA_RS07665	COG3292	Two component regulator propeller
BACSA_RS07665	COG0745	RESPONSE REGULATOR receiver
BACSA_RS07670	COG0702	epimerase
BACSA_RS07675	COG4771	TonB-dependent receptor
BACSA_RS07690	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BACSA_RS07700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BACSA_RS07710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BACSA_RS07715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BACSA_RS07720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BACSA_RS07725	COG0131	Imidazoleglycerol-phosphate dehydratase
BACSA_RS07745	COG0318	PFAM AMP-dependent synthetase and ligase
BACSA_RS07755	COG1538	Outer membrane efflux protein
BACSA_RS07765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS07785	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BACSA_RS07790	COG0514	ATP-dependent DNA helicase (RecQ)
BACSA_RS07795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BACSA_RS07795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BACSA_RS07805	COG0006	proline dipeptidase activity
BACSA_RS07820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BACSA_RS07825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BACSA_RS07845	COG0443	Heat shock 70 kDa protein
BACSA_RS07900	COG2433	Pfam Transposase IS66
BACSA_RS07925	COG1501	Belongs to the glycosyl hydrolase 31 family
BACSA_RS07945	COG4771	TonB-dependent receptor
BACSA_RS07955	COG1595	DNA-templated transcription, initiation
BACSA_RS07965	COG1522	sequence-specific DNA binding
BACSA_RS07975	COG3426	butyrate kinase activity
BACSA_RS07980	COG0280	phosphate acetyltransferase
BACSA_RS07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BACSA_RS08005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BACSA_RS08045	COG4771	TonB-dependent receptor
BACSA_RS08055	COG2205	protein histidine kinase activity
BACSA_RS08055	COG0745	RESPONSE REGULATOR receiver
BACSA_RS08055	COG3292	Two component regulator propeller
BACSA_RS08060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BACSA_RS08110	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACSA_RS08120	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BACSA_RS08125	COG2239	Acts as a magnesium transporter
BACSA_RS08130	COG1196	nuclear chromosome segregation
BACSA_RS08140	COG2755	lipolytic protein G-D-S-L family
BACSA_RS08140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BACSA_RS08155	COG0745	RESPONSE REGULATOR receiver
BACSA_RS08165	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BACSA_RS08180	COG1696	Membrane protein involved in D-alanine export
BACSA_RS08195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACSA_RS08210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS08225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BACSA_RS08265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BACSA_RS08275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BACSA_RS08280	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BACSA_RS08295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BACSA_RS08305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BACSA_RS08360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BACSA_RS08365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BACSA_RS08370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BACSA_RS08375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BACSA_RS08385	COG0242	peptide deformylase activity
BACSA_RS08390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BACSA_RS08425	COG4977	sequence-specific DNA binding
BACSA_RS08425	COG1917	Cupin 2, conserved barrel domain protein
BACSA_RS08445	COG0443	Heat shock 70 kDa protein
BACSA_RS08490	COG0662	Cupin 2, conserved barrel domain protein
BACSA_RS08490	COG2207	Transcriptional regulator
BACSA_RS08505	COG4771	TonB-dependent receptor
BACSA_RS08510	COG0561	phosphatase activity
BACSA_RS08525	COG4124	Belongs to the glycosyl hydrolase 26 family
BACSA_RS08530	COG4124	Belongs to the glycosyl hydrolase 26 family
BACSA_RS08535	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BACSA_RS08540	COG2211	Major facilitator Superfamily
BACSA_RS08545	COG2942	2-epimerase
BACSA_RS08555	COG1309	transcriptional regulator
BACSA_RS08570	COG1132	(ABC) transporter
BACSA_RS08580	COG3681	Belongs to the UPF0597 family
BACSA_RS08590	COG1346	cytolysis
BACSA_RS08600	COG0280	phosphate acetyltransferase
BACSA_RS08605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BACSA_RS08610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BACSA_RS08670	COG1216	Glycosyl transferase, family 2
BACSA_RS08680	COG0438	transferase activity, transferring glycosyl groups
BACSA_RS08725	COG2003	Belongs to the UPF0758 family
BACSA_RS08730	COG1216	Glycosyl transferase, family 2
BACSA_RS08730	COG0463	Glycosyl transferase, family 2
BACSA_RS08735	COG0586	Pfam SNARE associated Golgi protein
BACSA_RS08765	COG0811	peptide transport
BACSA_RS08775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BACSA_RS08785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BACSA_RS08790	COG0569	domain protein
BACSA_RS08800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACSA_RS08805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACSA_RS08810	COG0649	NAD binding
BACSA_RS08810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACSA_RS08815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BACSA_RS08825	COG0839	Belongs to the complex I subunit 6 family
BACSA_RS08830	COG0713	ATP synthesis coupled electron transport
BACSA_RS08835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BACSA_RS08840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BACSA_RS08845	COG1007	ATP synthesis coupled electron transport
BACSA_RS08900	COG0488	(ABC) transporter
BACSA_RS08905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BACSA_RS08935	COG0514	ATP-dependent DNA helicase (RecQ)
BACSA_RS08975	COG2161	toxin-antitoxin pair type II binding
BACSA_RS09030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BACSA_RS09040	COG3292	Two component regulator propeller
BACSA_RS09040	COG0745	RESPONSE REGULATOR receiver
BACSA_RS09040	COG2205	protein histidine kinase activity
BACSA_RS09040	COG3292	Two component regulator propeller
BACSA_RS09040	COG0745	RESPONSE REGULATOR receiver
BACSA_RS09040	COG2205	protein histidine kinase activity
BACSA_RS09065	COG0545	Peptidyl-prolyl cis-trans isomerase
BACSA_RS09070	COG0423	glycine-tRNA ligase activity
BACSA_RS09090	COG0534	Mate efflux family protein
BACSA_RS09115	COG5002	protein histidine kinase activity
BACSA_RS09165	COG2770	Histidine kinase
BACSA_RS09165	COG2208	phosphoserine phosphatase activity
BACSA_RS09180	COG0028	Belongs to the TPP enzyme family
BACSA_RS09240	COG1496	oxidoreductase activity
BACSA_RS09245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BACSA_RS09250	COG0563	adenylate kinase activity
BACSA_RS09260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BACSA_RS09260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BACSA_RS09285	COG0124	histidyl-tRNA synthetase
BACSA_RS09295	COG0194	GDP metabolic process
BACSA_RS09305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BACSA_RS09310	COG1575	Belongs to the MenA family. Type 1 subfamily
BACSA_RS09315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BACSA_RS09320	COG0179	Fumarylacetoacetate (FAA) hydrolase
BACSA_RS09325	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BACSA_RS09330	COG0023	Translation Initiation Factor
BACSA_RS09335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BACSA_RS09340	COG0459	protein refolding
BACSA_RS09345	COG0590	tRNA wobble adenosine to inosine editing
BACSA_RS09355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BACSA_RS09360	COG3142	Participates in the control of copper homeostasis
BACSA_RS09365	COG0561	phosphatase activity
BACSA_RS09375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BACSA_RS09400	COG1917	Cupin 2, conserved barrel domain protein
BACSA_RS09400	COG1396	sequence-specific DNA binding
BACSA_RS09405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BACSA_RS09410	COG0254	rRNA binding
BACSA_RS09420	COG0191	fructose-bisphosphate aldolase activity
BACSA_RS09450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS09460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BACSA_RS09465	COG0052	Belongs to the universal ribosomal protein uS2 family
BACSA_RS09470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BACSA_RS09475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BACSA_RS09490	COG0017	Asparaginyl-tRNA synthetase
BACSA_RS09495	COG1187	pseudouridine synthase activity
BACSA_RS09530	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS09550	COG4206	TonB-dependent receptor
BACSA_RS09550	COG1629	transport
BACSA_RS09560	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS09565	COG3292	Two component regulator propeller
BACSA_RS09565	COG2205	protein histidine kinase activity
BACSA_RS09565	COG0745	RESPONSE REGULATOR receiver
BACSA_RS09580	COG0756	dUTP diphosphatase activity
BACSA_RS09630	COG1733	regulation of RNA biosynthetic process
BACSA_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS09655	COG0656	L-ascorbic acid biosynthetic process
BACSA_RS09660	COG0667	Aldo Keto reductase
BACSA_RS09685	COG0656	L-ascorbic acid biosynthetic process
BACSA_RS09690	COG0110	maltose O-acetyltransferase activity
BACSA_RS09695	COG0656	L-ascorbic acid biosynthetic process
BACSA_RS09765	COG0454	-acetyltransferase
BACSA_RS09795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BACSA_RS09815	COG1733	regulation of RNA biosynthetic process
BACSA_RS09825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BACSA_RS09840	COG2197	response regulator
BACSA_RS09860	COG0667	Aldo Keto reductase
BACSA_RS09865	COG2207	Transcriptional regulator
BACSA_RS09890	COG1924	4 iron, 4 sulfur cluster binding
BACSA_RS09895	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BACSA_RS09900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BACSA_RS09905	COG0509	glycine decarboxylation via glycine cleavage system
BACSA_RS09910	COG3250	beta-galactosidase activity
BACSA_RS09935	COG0793	Belongs to the peptidase S41A family
BACSA_RS09960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BACSA_RS09965	COG0203	ribosomal protein L17
BACSA_RS09970	COG0202	RNA polymerase activity
BACSA_RS09975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BACSA_RS09980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BACSA_RS09985	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BACSA_RS09990	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BACSA_RS10005	COG0200	Binds to the 23S rRNA
BACSA_RS10010	COG1841	ribosomal large subunit assembly
BACSA_RS10015	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BACSA_RS10020	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BACSA_RS10025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BACSA_RS10030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BACSA_RS10035	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BACSA_RS10040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BACSA_RS10045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BACSA_RS10050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BACSA_RS10055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BACSA_RS10060	COG0255	Belongs to the universal ribosomal protein uL29 family
BACSA_RS10065	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BACSA_RS10070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BACSA_RS10075	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BACSA_RS10080	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BACSA_RS10085	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BACSA_RS10090	COG0089	rRNA binding
BACSA_RS10095	COG0088	Forms part of the polypeptide exit tunnel
BACSA_RS10100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BACSA_RS10105	COG0051	transcription antitermination factor activity, RNA binding
BACSA_RS10110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BACSA_RS10115	COG0049	tRNA binding
BACSA_RS10120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BACSA_RS10130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BACSA_RS10135	COG0849	cell division
BACSA_RS10145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BACSA_RS10150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BACSA_RS10155	COG0772	Belongs to the SEDS family
BACSA_RS10160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BACSA_RS10165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACSA_RS10170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BACSA_RS10175	COG0768	penicillin binding
BACSA_RS10185	COG0275	rRNA processing
BACSA_RS10205	COG0733	neurotransmitter:sodium symporter activity
BACSA_RS10215	COG1785	Belongs to the alkaline phosphatase family
BACSA_RS10220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BACSA_RS10225	COG2233	PERMEase
BACSA_RS10250	COG2166	iron-sulfur cluster assembly
BACSA_RS10255	COG2234	aminopeptidase activity
BACSA_RS10265	COG1022	Amp-dependent synthetase and ligase
BACSA_RS10275	COG2954	triphosphatase activity
BACSA_RS10280	COG1595	DNA-templated transcription, initiation
BACSA_RS10285	COG1381	Involved in DNA repair and RecF pathway recombination
BACSA_RS10295	COG0268	Binds directly to 16S ribosomal RNA
BACSA_RS10300	COG0187	DNA topoisomerase II activity
BACSA_RS10305	COG1640	4-alpha-glucanotransferase
BACSA_RS10340	COG2096	Adenosyltransferase
BACSA_RS10355	COG3594	Acyltransferase
BACSA_RS10365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BACSA_RS10375	COG2873	o-acetylhomoserine
BACSA_RS10380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACSA_RS10400	COG0165	Argininosuccinate lyase
BACSA_RS10410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BACSA_RS10415	COG1040	competence protein
BACSA_RS10425	COG2890	protein-(glutamine-N5) methyltransferase activity
BACSA_RS10430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BACSA_RS10430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BACSA_RS10440	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BACSA_RS10460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BACSA_RS10480	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS10485	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS10490	COG2382	esterase
BACSA_RS10495	COG2382	esterase
BACSA_RS10500	COG3693	PFAM glycoside hydrolase, family 10
BACSA_RS10500	COG2382	esterase
BACSA_RS10500	COG3507	Belongs to the glycosyl hydrolase 43 family
BACSA_RS10505	COG0702	epimerase
BACSA_RS10510	COG1629	transport
BACSA_RS10515	COG2272	Belongs to the type-B carboxylesterase lipase family
BACSA_RS10520	COG2205	protein histidine kinase activity
BACSA_RS10520	COG0745	RESPONSE REGULATOR receiver
BACSA_RS10520	COG3292	Two component regulator propeller
BACSA_RS10525	COG1629	transport
BACSA_RS10525	COG4206	TonB-dependent receptor
BACSA_RS10530	COG0702	epimerase
BACSA_RS10540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BACSA_RS10545	COG1053	succinate dehydrogenase
BACSA_RS10565	COG2885	chlorophyll binding
BACSA_RS10570	COG0482	sulfurtransferase activity
BACSA_RS10580	COG2255	four-way junction helicase activity
BACSA_RS10590	COG0513	Belongs to the DEAD box helicase family
BACSA_RS10595	COG3655	Transcriptional regulator
BACSA_RS10635	COG1082	Xylose isomerase domain protein TIM barrel
BACSA_RS10640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BACSA_RS10650	COG0196	riboflavin kinase activity
BACSA_RS10655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BACSA_RS10900	COG4974	Belongs to the 'phage' integrase family
BACSA_RS10905	COG4974	Belongs to the 'phage' integrase family
BACSA_RS10940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BACSA_RS10945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BACSA_RS10950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BACSA_RS10955	COG1480	7TM receptor with intracellular HD hydrolase
BACSA_RS10960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BACSA_RS11010	COG0545	Peptidyl-prolyl cis-trans isomerase
BACSA_RS11020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BACSA_RS11025	COG1773	rubredoxin
BACSA_RS11030	COG1185	polyribonucleotide nucleotidyltransferase activity
BACSA_RS11045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BACSA_RS11115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BACSA_RS11120	COG3408	Glycogen debranching enzyme
BACSA_RS11125	COG1217	gtp-binding protein TYPA
BACSA_RS11135	COG2197	response regulator
BACSA_RS11140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BACSA_RS11155	COG2223	nitrite transmembrane transporter activity
BACSA_RS11160	COG1132	(ABC) transporter
BACSA_RS11165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BACSA_RS11170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BACSA_RS11175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BACSA_RS11180	COG0571	ribonuclease III activity
BACSA_RS11185	COG0363	glucosamine-6-phosphate deaminase activity
BACSA_RS11200	COG4942	peptidase
BACSA_RS11230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACSA_RS11265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BACSA_RS11305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BACSA_RS11310	COG0116	Belongs to the methyltransferase superfamily
BACSA_RS11315	COG0823	Involved in the tonB-independent uptake of proteins
BACSA_RS11315	COG1506	peptidase
BACSA_RS11320	COG0151	Belongs to the GarS family
BACSA_RS11330	COG1238	metal cluster binding
BACSA_RS11370	COG0534	Mate efflux family protein
BACSA_RS11375	COG0110	maltose O-acetyltransferase activity
BACSA_RS11385	COG0148	phosphopyruvate hydratase activity
BACSA_RS11390	COG1592	Rubrerythrin
BACSA_RS11395	COG0659	secondary active sulfate transmembrane transporter activity
BACSA_RS11405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BACSA_RS11415	COG0427	acetyl-CoA hydrolase
BACSA_RS11420	COG3250	beta-galactosidase activity
BACSA_RS11430	COG4206	TonB-dependent receptor
BACSA_RS11430	COG1629	transport
BACSA_RS11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACSA_RS11445	COG0501	Belongs to the peptidase M48B family
BACSA_RS11455	COG0495	leucyl-tRNA aminoacylation
BACSA_RS11460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BACSA_RS11465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BACSA_RS11515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BACSA_RS11525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BACSA_RS11540	COG0731	radical SAM domain protein
BACSA_RS11540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BACSA_RS11550	COG2177	Part of the ABC transporter FtsEX involved in
BACSA_RS11560	COG1968	undecaprenyl-diphosphatase activity
BACSA_RS11565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BACSA_RS11570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BACSA_RS11575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BACSA_RS11580	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BACSA_RS11585	COG1611	Belongs to the LOG family
BACSA_RS11600	COG0594	ribonuclease P activity
BACSA_RS11605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BACSA_RS11615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BACSA_RS11620	COG0339	signal peptide processing
BACSA_RS11635	COG1629	transport
BACSA_RS11635	COG4206	TonB-dependent receptor
BACSA_RS11650	COG1073	alpha beta
BACSA_RS11665	COG3940	Belongs to the glycosyl hydrolase 43 family
BACSA_RS11670	COG1854	S-ribosylhomocysteine lyase activity
BACSA_RS11675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BACSA_RS11700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BACSA_RS11705	COG3409	Peptidoglycan-binding domain 1 protein
BACSA_RS11705	COG0793	Belongs to the peptidase S41A family
BACSA_RS11715	COG0758	DNA mediated transformation
BACSA_RS11715	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BACSA_RS11730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BACSA_RS11740	COG0681	Belongs to the peptidase S26 family
BACSA_RS11785	COG0438	transferase activity, transferring glycosyl groups
BACSA_RS11820	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
BACSA_RS11825	COG0438	transferase activity, transferring glycosyl groups
BACSA_RS11825	COG4641	Protein conserved in bacteria
BACSA_RS11840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BACSA_RS11840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BACSA_RS11855	COG1045	serine acetyltransferase
BACSA_RS11860	COG0205	6-phosphofructokinase activity
BACSA_RS11905	COG0215	cysteine-tRNA ligase activity
BACSA_RS11915	COG0482	sulfurtransferase activity
BACSA_RS11950	COG0012	GTP binding
BACSA_RS11970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BACSA_RS11970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BACSA_RS11975	COG0142	geranyltranstransferase activity
BACSA_RS11980	COG4771	TonB-dependent receptor
BACSA_RS11985	COG0702	epimerase
BACSA_RS12050	COG1694	Mazg nucleotide pyrophosphohydrolase
BACSA_RS12055	COG1490	D-aminoacyl-tRNA deacylase activity
BACSA_RS12060	COG0322	excinuclease ABC activity
BACSA_RS12065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BACSA_RS12070	COG0445	tRNA wobble uridine modification
BACSA_RS12075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BACSA_RS12080	COG2715	membrane protein required for spore maturation
BACSA_RS12090	COG3341	Caulimovirus viroplasmin
BACSA_RS12090	COG0328	RNA-DNA hybrid ribonuclease activity
BACSA_RS12095	COG0018	arginyl-trna synthetase
BACSA_RS12125	COG0612	Peptidase, M16
BACSA_RS12165	COG1454	alcohol dehydrogenase
BACSA_RS12190	COG2027	D-alanyl-D-alanine carboxypeptidase
BACSA_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS12215	COG3250	beta-galactosidase activity
BACSA_RS12245	COG1121	(ABC) transporter
BACSA_RS12285	COG0606	chelatase, subunit chli
BACSA_RS12300	COG4974	Belongs to the 'phage' integrase family
BACSA_RS12305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BACSA_RS12320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BACSA_RS12325	COG4591	ABC-type transport system involved in lipoprotein release permease component
BACSA_RS12340	COG0557	exoribonuclease II activity
BACSA_RS12345	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BACSA_RS12350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BACSA_RS12365	COG4974	Belongs to the 'phage' integrase family
BACSA_RS12400	COG1388	LysM domain
BACSA_RS12400	COG4932	domain protein
BACSA_RS12475	COG0004	ammonium transporteR
BACSA_RS12480	COG0347	Belongs to the P(II) protein family
BACSA_RS12500	COG0149	triose-phosphate isomerase activity
BACSA_RS12510	COG0302	gtp cyclohydrolase
BACSA_RS12525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BACSA_RS12530	COG0826	peptidase U32
BACSA_RS12535	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BACSA_RS12540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BACSA_RS12545	COG1013	pyruvate-flavodoxin oxidoreductase activity
BACSA_RS12550	COG0674	pyruvate-flavodoxin oxidoreductase activity
BACSA_RS12550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BACSA_RS12560	COG0602	queuosine metabolic process
BACSA_RS12570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BACSA_RS12580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BACSA_RS12590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BACSA_RS12595	COG4974	Belongs to the 'phage' integrase family
BACSA_RS12625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BACSA_RS12640	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BACSA_RS12645	COG0081	regulation of translation
BACSA_RS12650	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BACSA_RS12655	COG0222	ribosome binding
BACSA_RS12660	COG0085	RNA polymerase activity
BACSA_RS12665	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BACSA_RS12690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BACSA_RS12695	COG4974	Belongs to the 'phage' integrase family
BACSA_RS12730	COG0551	DNA topoisomerase type I activity
BACSA_RS12730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BACSA_RS12750	COG2198	Histidine kinase
BACSA_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BACSA_RS12750	COG2205	protein histidine kinase activity
BACSA_RS12750	COG0784	Response regulator, receiver
BACSA_RS12870	COG0358	DNA primase activity
BACSA_RS12960	COG0673	inositol 2-dehydrogenase activity
BACSA_RS12965	COG0632	four-way junction helicase activity
BACSA_RS12970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BACSA_RS12975	COG0805	protein transport
BACSA_RS12980	COG0616	signal peptide processing
BACSA_RS12985	COG1663	tetraacyldisaccharide 4'-kinase activity
BACSA_RS12990	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BACSA_RS12995	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BACSA_RS13035	COG0673	inositol 2-dehydrogenase activity
BACSA_RS13040	COG1482	cell wall glycoprotein biosynthetic process
BACSA_RS13045	COG3458	cephalosporin-C deacetylase activity
BACSA_RS13050	COG1629	transport
BACSA_RS13050	COG4206	TonB-dependent receptor
BACSA_RS13055	COG0702	epimerase
BACSA_RS13065	COG2271	Major facilitator Superfamily
BACSA_RS13070	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BACSA_RS13075	COG3775	system Galactitol-specific IIC component
BACSA_RS13080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS13095	COG3250	beta-galactosidase activity
BACSA_RS13100	COG0745	RESPONSE REGULATOR receiver
BACSA_RS13100	COG2205	protein histidine kinase activity
BACSA_RS13100	COG3292	Two component regulator propeller
BACSA_RS13105	COG0668	transmembrane transport
BACSA_RS13115	COG2086	electron transfer activity
BACSA_RS13120	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BACSA_RS13165	COG1970	mechanosensitive ion channel activity
BACSA_RS13185	COG1073	alpha beta
BACSA_RS13190	COG2755	lipolytic protein G-D-S-L family
BACSA_RS13225	COG1070	Carbohydrate kinase
BACSA_RS13230	COG4806	L-rhamnose isomerase
BACSA_RS13240	COG0235	Class ii aldolase
BACSA_RS13245	COG1454	alcohol dehydrogenase
BACSA_RS13255	COG0037	tRNA processing
BACSA_RS13260	COG0562	UDP-galactopyranose mutase
BACSA_RS13265	COG3279	Response regulator of the LytR AlgR family
BACSA_RS13275	COG1136	(ABC) transporter
BACSA_RS13275	COG0577	efflux transmembrane transporter activity
BACSA_RS13280	COG1136	(ABC) transporter
BACSA_RS13285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS13300	COG1271	oxidase subunit
BACSA_RS13340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BACSA_RS13345	COG0742	ribosomal rna small subunit methyltransferase
BACSA_RS13390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BACSA_RS13450	COG2217	Heavy metal translocating P-type atpase
BACSA_RS13525	COG2205	protein histidine kinase activity
BACSA_RS13525	COG3292	Two component regulator propeller
BACSA_RS13525	COG3292	Two component regulator propeller
BACSA_RS13525	COG2205	protein histidine kinase activity
BACSA_RS13525	COG0745	RESPONSE REGULATOR receiver
BACSA_RS13525	COG0745	RESPONSE REGULATOR receiver
BACSA_RS13545	COG4206	TonB-dependent receptor
BACSA_RS13545	COG1629	transport
BACSA_RS13570	COG0708	Exodeoxyribonuclease III
BACSA_RS13580	COG1388	LysM domain
BACSA_RS13580	COG3942	CHAP domain
BACSA_RS13585	COG0436	Aminotransferase
BACSA_RS13590	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BACSA_RS13595	COG0367	asparagine synthase
BACSA_RS13605	COG0069	glutamate synthase activity
BACSA_RS13605	COG0070	glutamate synthase
BACSA_RS13605	COG0067	glutamate synthase
BACSA_RS13615	COG0667	Aldo Keto reductase
BACSA_RS13625	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS13650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BACSA_RS13650	COG1918	ferrous iron import across plasma membrane
BACSA_RS13685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BACSA_RS13690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BACSA_RS13695	COG1160	GTP binding
BACSA_RS13705	COG1328	CTP reductase activity
BACSA_RS13710	COG0617	tRNA 3'-terminal CCA addition
BACSA_RS13770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BACSA_RS13785	COG4464	protein tyrosine phosphatase activity
BACSA_RS13835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BACSA_RS13880	COG0297	glycogen (starch) synthase activity
BACSA_RS13895	COG0110	maltose O-acetyltransferase activity
BACSA_RS13900	COG0463	Glycosyl transferase, family 2
BACSA_RS13915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BACSA_RS13925	COG0779	Required for maturation of 30S ribosomal subunits
BACSA_RS13930	COG0195	Participates in both transcription termination and antitermination
BACSA_RS13930	COG2251	uridine kinase activity
BACSA_RS13935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BACSA_RS13945	COG0719	Fe-S assembly protein
BACSA_RS13950	COG0396	ATPase activity
BACSA_RS13955	COG0719	Fe-S assembly protein
BACSA_RS13960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BACSA_RS13970	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BACSA_RS13970	COG3408	Glycogen debranching enzyme
BACSA_RS13980	COG2431	L-lysine efflux transmembrane transporter activity
BACSA_RS13995	COG0702	epimerase
BACSA_RS14000	COG4206	TonB-dependent receptor
BACSA_RS14000	COG1629	transport
BACSA_RS14025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BACSA_RS14030	COG0811	peptide transport
BACSA_RS14035	COG0848	biopolymer transport protein
BACSA_RS14050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BACSA_RS14055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BACSA_RS14060	COG0481	GTPase activity
BACSA_RS14065	COG0534	Mate efflux family protein
BACSA_RS14075	COG2211	Major facilitator Superfamily
BACSA_RS14095	COG1501	Belongs to the glycosyl hydrolase 31 family
BACSA_RS14100	COG3507	Belongs to the glycosyl hydrolase 43 family
BACSA_RS14105	COG3507	Belongs to the glycosyl hydrolase 43 family
BACSA_RS14110	COG3507	Belongs to the glycosyl hydrolase 43 family
BACSA_RS14115	COG4771	TonB-dependent receptor
BACSA_RS14130	COG2205	protein histidine kinase activity
BACSA_RS14130	COG3292	Two component regulator propeller
BACSA_RS14130	COG0745	RESPONSE REGULATOR receiver
BACSA_RS14135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BACSA_RS14140	COG4657	Part of a membrane complex involved in electron transport
BACSA_RS14145	COG4660	Part of a membrane complex involved in electron transport
BACSA_RS14150	COG4659	FMN binding
BACSA_RS14155	COG4658	electron transport chain
BACSA_RS14160	COG4656	Part of a membrane complex involved in electron transport
BACSA_RS14185	COG0739	heme binding
BACSA_RS14190	COG0358	DNA primase activity
BACSA_RS14205	COG0039	L-malate dehydrogenase activity
BACSA_RS14220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BACSA_RS14220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BACSA_RS14225	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BACSA_RS14225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BACSA_RS14265	COG0464	growth
BACSA_RS14275	COG1621	beta-fructofuranosidase activity
BACSA_RS14290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BACSA_RS14300	COG3292	Two component regulator propeller
BACSA_RS14300	COG2205	protein histidine kinase activity
BACSA_RS14300	COG0745	RESPONSE REGULATOR receiver
BACSA_RS14305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BACSA_RS14310	COG1438	arginine binding
BACSA_RS14320	COG0137	argininosuccinate synthase activity
BACSA_RS14325	COG1983	PspC domain protein
BACSA_RS14330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BACSA_RS14340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BACSA_RS14350	COG4771	TonB-dependent receptor
BACSA_RS14385	COG1629	transport
BACSA_RS14385	COG4206	TonB-dependent receptor
BACSA_RS14390	COG1373	ATPase (AAA superfamily
BACSA_RS14405	COG1629	transport
BACSA_RS14405	COG4206	TonB-dependent receptor
BACSA_RS14420	COG4974	Belongs to the 'phage' integrase family
BACSA_RS14425	COG1629	transport
BACSA_RS14435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BACSA_RS14445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BACSA_RS14450	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BACSA_RS14450	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BACSA_RS14455	COG3022	response to hydroperoxide
BACSA_RS14460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BACSA_RS14500	COG0138	bifunctional purine biosynthesis protein purh
BACSA_RS14525	COG5002	protein histidine kinase activity
BACSA_RS14530	COG0745	RESPONSE REGULATOR receiver
BACSA_RS14535	COG4206	TonB-dependent receptor
BACSA_RS14550	COG0288	reversible hydration of carbon dioxide
BACSA_RS14580	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BACSA_RS14585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BACSA_RS14590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BACSA_RS14595	COG0066	3-isopropylmalate dehydratase activity
BACSA_RS14620	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS14635	COG1649	PFAM Uncharacterised BCR, COG1649
BACSA_RS14645	COG0287	Prephenate dehydrogenase
BACSA_RS14645	COG1605	Chorismate mutase
BACSA_RS14650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BACSA_RS14685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BACSA_RS14690	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BACSA_RS14695	COG1169	isochorismate synthase
BACSA_RS14710	COG3385	transposase activity
BACSA_RS14715	COG1252	NADH dehydrogenase
BACSA_RS14720	COG0110	maltose O-acetyltransferase activity
BACSA_RS14725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BACSA_RS14745	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BACSA_RS14750	COG4770	biotin carboxylase activity
BACSA_RS14760	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BACSA_RS14765	COG0346	lactoylglutathione lyase activity
BACSA_RS14780	COG0778	Nitroreductase
BACSA_RS14795	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BACSA_RS14800	COG0424	maF-like protein
BACSA_RS14805	COG1530	ribonuclease E activity
BACSA_RS14810	COG0776	regulation of translation
BACSA_RS14815	COG1194	a g-specific adenine glycosylase
BACSA_RS14820	COG0629	single-stranded DNA binding
BACSA_RS14835	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BACSA_RS14840	COG1091	dTDP-4-dehydrorhamnose reductase activity
BACSA_RS14845	COG5002	protein histidine kinase activity
BACSA_RS14850	COG0745	RESPONSE REGULATOR receiver
BACSA_RS14855	COG0252	asparaginase activity
BACSA_RS14860	COG0159	tryptophan synthase activity
BACSA_RS14865	COG0135	phosphoribosylanthranilate isomerase activity
BACSA_RS14870	COG0134	indole-3-glycerol-phosphate synthase activity
BACSA_RS14875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BACSA_RS14880	COG0512	Glutamine amidotransferase of anthranilate synthase
BACSA_RS14885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BACSA_RS14890	COG0133	tryptophan synthase activity
BACSA_RS14915	COG0516	GMP reductase activity
BACSA_RS14915	COG0517	IMP dehydrogenase activity
BACSA_RS14930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BACSA_RS14945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BACSA_RS14975	COG0564	pseudouridine synthase activity
BACSA_RS15005	COG4771	TonB-dependent receptor
BACSA_RS15020	COG4771	TonB-dependent receptor
BACSA_RS15030	COG3401	FG-GAP repeat protein
BACSA_RS15040	COG3250	beta-galactosidase activity
BACSA_RS15050	COG2755	lipolytic protein G-D-S-L family
BACSA_RS15055	COG3254	rhamnose metabolic process
BACSA_RS15060	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BACSA_RS15065	COG0352	thiamine-phosphate diphosphorylase activity
BACSA_RS15065	COG0351	phosphomethylpyrimidine kinase
BACSA_RS15075	COG1070	Carbohydrate kinase
BACSA_RS15080	COG2115	Belongs to the xylose isomerase family
BACSA_RS15085	COG0477	Major facilitator Superfamily
BACSA_RS15085	COG2814	Major facilitator Superfamily
BACSA_RS15100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS15105	COG3401	FG-GAP repeat protein
BACSA_RS15110	COG5434	Belongs to the glycosyl hydrolase 28 family
BACSA_RS15130	COG2205	protein histidine kinase activity
BACSA_RS15130	COG3292	Two component regulator propeller
BACSA_RS15130	COG0745	RESPONSE REGULATOR receiver
BACSA_RS15130	COG2205	protein histidine kinase activity
BACSA_RS15130	COG3292	Two component regulator propeller
BACSA_RS15130	COG0745	RESPONSE REGULATOR receiver
BACSA_RS15135	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS15155	COG0335	large ribosomal subunit rRNA binding
BACSA_RS15165	COG0737	Belongs to the 5'-nucleotidase family
BACSA_RS15170	COG1472	Belongs to the glycosyl hydrolase 3 family
BACSA_RS15175	COG0363	glucosamine-6-phosphate deaminase activity
BACSA_RS15180	COG0363	glucosamine-6-phosphate deaminase activity
BACSA_RS15190	COG2895	sulfate adenylyltransferase (ATP) activity
BACSA_RS15195	COG0175	sulfate reduction
BACSA_RS15200	COG0529	Catalyzes the synthesis of activated sulfate
BACSA_RS15205	COG0471	metal ion transport
BACSA_RS15205	COG3273	potassium ion transport
BACSA_RS15210	COG1218	3'(2'),5'-bisphosphate nucleotidase
BACSA_RS15215	COG0531	amino acid
BACSA_RS15270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BACSA_RS15275	COG1166	arginine decarboxylase activity
BACSA_RS15285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BACSA_RS15305	COG2814	Major facilitator Superfamily
BACSA_RS15315	COG4591	ABC-type transport system involved in lipoprotein release permease component
BACSA_RS15315	COG1136	(ABC) transporter
BACSA_RS15360	COG0745	RESPONSE REGULATOR receiver
BACSA_RS15360	COG2205	protein histidine kinase activity
BACSA_RS15360	COG3292	Two component regulator propeller
BACSA_RS15390	COG1418	mRNA catabolic process
BACSA_RS15420	COG1538	Outer membrane efflux protein
BACSA_RS15430	COG1136	(ABC) transporter
BACSA_RS15430	COG0577	efflux transmembrane transporter activity
BACSA_RS15435	COG1136	(ABC) transporter
BACSA_RS15435	COG0577	efflux transmembrane transporter activity
BACSA_RS15440	COG1136	(ABC) transporter
BACSA_RS15450	COG1127	ABC transporter
BACSA_RS15455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BACSA_RS15460	COG1137	ATPase activity
BACSA_RS15465	COG0544	peptidyl-prolyl cis-trans isomerase activity
BACSA_RS15470	COG0740	serine-type endopeptidase activity
BACSA_RS15475	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BACSA_RS15480	COG0514	ATP-dependent DNA helicase (RecQ)
BACSA_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS15530	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BACSA_RS15570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BACSA_RS15720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BACSA_RS15725	COG0776	regulation of translation
BACSA_RS15910	COG2204	response regulator
BACSA_RS15915	COG2205	protein histidine kinase activity
BACSA_RS15915	COG2198	Histidine kinase
BACSA_RS15915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BACSA_RS15915	COG0784	Response regulator, receiver
BACSA_RS16055	COG4974	Belongs to the 'phage' integrase family
BACSA_RS16120	COG1373	ATPase (AAA superfamily
BACSA_RS16150	COG1373	ATPase (AAA superfamily
BACSA_RS16315	COG3831	ATPase activity
BACSA_RS16315	COG4884	unkown
BACSA_RS16365	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BACSA_RS16365	COG0551	DNA topoisomerase type I activity
BACSA_RS16420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BACSA_RS16495	COG2076	Multidrug Resistance protein
BACSA_RS16510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BACSA_RS16525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BACSA_RS16530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BACSA_RS16540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BACSA_RS16545	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BACSA_RS16550	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS16560	COG4771	TonB-dependent receptor
BACSA_RS16570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BACSA_RS16575	COG0436	Aminotransferase
BACSA_RS16580	COG0670	Belongs to the BI1 family
BACSA_RS16585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BACSA_RS16585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BACSA_RS16615	COG0205	6-phosphofructokinase activity
BACSA_RS16620	COG0546	phosphoglycolate phosphatase activity
BACSA_RS16640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BACSA_RS16665	COG1242	4 iron, 4 sulfur cluster binding
BACSA_RS16670	COG0426	domain, Protein
BACSA_RS16675	COG0009	L-threonylcarbamoyladenylate synthase
BACSA_RS16680	COG0668	transmembrane transport
BACSA_RS16685	COG3250	beta-galactosidase activity
BACSA_RS16695	COG0457	Tetratricopeptide repeat
BACSA_RS16700	COG2814	Major facilitator Superfamily
BACSA_RS16700	COG0477	Major facilitator Superfamily
BACSA_RS16745	COG0534	Mate efflux family protein
BACSA_RS16750	COG1570	exodeoxyribonuclease VII activity
BACSA_RS16760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BACSA_RS16775	COG0489	protein tyrosine kinase activity
BACSA_RS16790	COG0793	Belongs to the peptidase S41A family
BACSA_RS16790	COG4946	Tricorn protease homolog
BACSA_RS16805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BACSA_RS16810	COG0589	response to stress
BACSA_RS16810	COG0475	glutathione-regulated potassium exporter activity
BACSA_RS16815	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BACSA_RS16820	COG1136	(ABC) transporter
BACSA_RS16830	COG1629	transport
BACSA_RS16830	COG4206	TonB-dependent receptor
BACSA_RS16840	COG2996	Protein conserved in bacteria
BACSA_RS16845	COG0205	6-phosphofructokinase activity
BACSA_RS16850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BACSA_RS16855	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BACSA_RS16870	COG0084	hydrolase, TatD family'
BACSA_RS16880	COG0811	peptide transport
BACSA_RS16910	COG1522	sequence-specific DNA binding
BACSA_RS16920	COG1183	phosphatidylcholine synthase activity
BACSA_RS16925	COG0688	phosphatidylethanolamine metabolic process
BACSA_RS16935	COG3118	belongs to the thioredoxin family
BACSA_RS16960	COG0802	atpase or kinase
BACSA_RS16965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BACSA_RS16980	COG0667	Aldo Keto reductase
BACSA_RS17000	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BACSA_RS17030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BACSA_RS17040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BACSA_RS17050	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BACSA_RS17055	COG2207	Transcriptional regulator
BACSA_RS17055	COG1609	Transcriptional regulator
BACSA_RS17060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BACSA_RS17075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BACSA_RS17075	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BACSA_RS17080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BACSA_RS17085	COG0284	orotidine-5'-phosphate decarboxylase activity
BACSA_RS17095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BACSA_RS17100	COG3177	Filamentation induced by cAMP protein fic
BACSA_RS17105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BACSA_RS17120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BACSA_RS17140	COG2205	protein histidine kinase activity
BACSA_RS17140	COG2205	protein histidine kinase activity
BACSA_RS17140	COG0745	RESPONSE REGULATOR receiver
BACSA_RS17140	COG3292	Two component regulator propeller
BACSA_RS17140	COG0745	RESPONSE REGULATOR receiver
BACSA_RS17140	COG3292	Two component regulator propeller
BACSA_RS17145	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BACSA_RS17155	COG2195	Cleaves the N-terminal amino acid of tripeptides
BACSA_RS17160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BACSA_RS17205	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BACSA_RS17300	COG3617	BRO family, N-terminal domain
BACSA_RS17415	COG1028	Short-chain dehydrogenase reductase Sdr
BACSA_RS17420	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BACSA_RS17465	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BACSA_RS17495	COG0513	Belongs to the DEAD box helicase family
BACSA_RS17505	COG0739	heme binding
BACSA_RS17570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BACSA_RS17575	COG1705	Flagellar rod assembly protein muramidase FlgJ
BACSA_RS17615	COG0592	DNA-directed DNA polymerase activity
BACSA_RS17700	COG4474	Belongs to the UPF0398 family
BACSA_RS17755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BACSA_RS17770	COG4974	Belongs to the 'phage' integrase family
BACSA_RS17785	COG2848	UPF0210 protein
BACSA_RS17840	COG0307	riboflavin synthase, alpha
BACSA_RS17845	COG3250	beta-galactosidase activity
BACSA_RS17885	COG1295	ribonuclease BN
BACSA_RS17890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BACSA_RS17905	COG3591	Belongs to the peptidase S1B family
BACSA_RS17910	COG3591	Belongs to the peptidase S1B family
BACSA_RS17935	COG0505	Belongs to the CarA family
BACSA_RS17940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BACSA_RS17945	COG2721	sulfolactate sulfo-lyase activity
BACSA_RS17950	COG1609	Transcriptional regulator
BACSA_RS18085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BACSA_RS18095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BACSA_RS18125	COG1475	DNA binding
BACSA_RS18130	COG3969	phosphoadenosine phosphosulfate
BACSA_RS18150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BACSA_RS18155	COG0352	thiamine-phosphate diphosphorylase activity
BACSA_RS18160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BACSA_RS18175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BACSA_RS18180	COG2022	thiamine diphosphate biosynthetic process
BACSA_RS18185	COG0352	thiamine-phosphate diphosphorylase activity
BACSA_RS18240	COG0247	lactate metabolic process
BACSA_RS18245	COG1139	Iron-sulfur cluster binding protein
BACSA_RS18270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BACSA_RS18275	COG0581	inorganic phosphate transmembrane transporter activity
BACSA_RS18280	COG0573	inorganic phosphate transmembrane transporter activity
BACSA_RS18285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BACSA_RS18295	COG0716	FMN binding
BACSA_RS18305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BACSA_RS18325	COG1629	transport
BACSA_RS18360	COG0058	SHG alpha-glucan phosphorylase activity
BACSA_RS18370	COG2801	Transposase and inactivated derivatives
BACSA_RS18385	COG0628	permease
BACSA_RS18395	COG0860	N-Acetylmuramoyl-L-alanine amidase
BACSA_RS18420	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BACSA_RS18465	COG0745	RESPONSE REGULATOR receiver
BACSA_RS18625	COG0126	phosphoglycerate kinase activity
BACSA_RS18700	COG3829	transcription factor binding
BACSA_RS18750	COG0488	(ABC) transporter
BACSA_RS18890	COG0631	protein serine/threonine phosphatase activity
BACSA_RS18925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BACSA_RS18990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)