locus-tag	class	description
EYA81_RS00190	COG0358	DNA primase activity
EYA81_RS00280	COG1136	(ABC) transporter
EYA81_RS00295	COG0501	Belongs to the peptidase M48B family
EYA81_RS00300	COG0156	8-amino-7-oxononanoate synthase activity
EYA81_RS00310	COG1597	lipid kinase activity
EYA81_RS00315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYA81_RS00330	COG2957	Belongs to the agmatine deiminase family
EYA81_RS00340	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EYA81_RS00345	COG0390	transport system, permease component
EYA81_RS00350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EYA81_RS00395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYA81_RS00410	COG0543	2 iron, 2 sulfur cluster binding
EYA81_RS00415	COG0167	dihydroorotate dehydrogenase activity
EYA81_RS00420	COG0336	Belongs to the RNA methyltransferase TrmD family
EYA81_RS00425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYA81_RS00430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYA81_RS00455	COG0542	response to heat
EYA81_RS00460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYA81_RS00480	COG3385	transposase activity
EYA81_RS00505	COG2304	oxidoreductase activity
EYA81_RS00520	COG0714	Associated with various cellular activities
EYA81_RS00535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYA81_RS00540	COG0552	protein localization to endoplasmic reticulum
EYA81_RS00550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYA81_RS00555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYA81_RS00560	COG1058	Belongs to the CinA family
EYA81_RS00560	COG1546	Belongs to the CinA family
EYA81_RS00565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYA81_RS00575	COG0305	Participates in initiation and elongation during chromosome replication
EYA81_RS00580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYA81_RS00590	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EYA81_RS00600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYA81_RS00605	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYA81_RS00615	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYA81_RS00620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYA81_RS00625	COG0534	Mate efflux family protein
EYA81_RS00635	COG0577	efflux transmembrane transporter activity
EYA81_RS00635	COG1136	(ABC) transporter
EYA81_RS00640	COG1136	(ABC) transporter
EYA81_RS00665	COG3852	Histidine kinase
EYA81_RS00670	COG3263	regulation of cellular component size
EYA81_RS00675	COG0318	PFAM AMP-dependent synthetase and ligase
EYA81_RS00680	COG1082	Xylose isomerase domain protein TIM barrel
EYA81_RS00700	COG0702	epimerase
EYA81_RS00705	COG4771	TonB-dependent receptor
EYA81_RS00720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYA81_RS00730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYA81_RS00730	COG2755	lipolytic protein G-D-S-L family
EYA81_RS00740	COG0842	Transport permease protein
EYA81_RS00745	COG1131	(ABC) transporter
EYA81_RS00760	COG2207	Transcriptional regulator
EYA81_RS00760	COG1917	Cupin 2, conserved barrel domain protein
EYA81_RS00765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYA81_RS00770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS00775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYA81_RS00780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYA81_RS00785	COG0505	Belongs to the CarA family
EYA81_RS00795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYA81_RS00800	COG0070	glutamate synthase
EYA81_RS00800	COG0069	glutamate synthase activity
EYA81_RS00800	COG0067	glutamate synthase
EYA81_RS00810	COG0367	asparagine synthase
EYA81_RS00820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYA81_RS00825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYA81_RS00845	COG1442	glycosyl transferase family 8
EYA81_RS00845	COG1216	Glycosyl transferase, family 2
EYA81_RS00855	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS00865	COG0110	maltose O-acetyltransferase activity
EYA81_RS00870	COG2244	polysaccharide biosynthetic process
EYA81_RS00920	COG0436	Aminotransferase
EYA81_RS00955	COG0133	tryptophan synthase activity
EYA81_RS00960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYA81_RS00965	COG0512	Glutamine amidotransferase of anthranilate synthase
EYA81_RS00965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYA81_RS00970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYA81_RS00975	COG0134	indole-3-glycerol-phosphate synthase activity
EYA81_RS00980	COG0135	phosphoribosylanthranilate isomerase activity
EYA81_RS00985	COG0159	tryptophan synthase activity
EYA81_RS00990	COG0252	asparaginase activity
EYA81_RS01000	COG0745	RESPONSE REGULATOR receiver
EYA81_RS01090	COG1442	glycosyl transferase family 8
EYA81_RS01090	COG1216	Glycosyl transferase, family 2
EYA81_RS01095	COG1216	Glycosyl transferase, family 2
EYA81_RS01100	COG1216	Glycosyl transferase, family 2
EYA81_RS01130	COG1609	Transcriptional regulator
EYA81_RS01135	COG2721	sulfolactate sulfo-lyase activity
EYA81_RS01145	COG0228	four-way junction DNA binding
EYA81_RS01150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYA81_RS01180	COG0588	phosphoglycerate mutase activity
EYA81_RS01190	COG0716	FMN binding
EYA81_RS01195	COG0058	SHG alpha-glucan phosphorylase activity
EYA81_RS01225	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EYA81_RS01275	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYA81_RS01285	COG0305	Participates in initiation and elongation during chromosome replication
EYA81_RS01315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYA81_RS01315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYA81_RS01330	COG2226	methyltransferase
EYA81_RS01340	COG1215	transferase activity, transferring glycosyl groups
EYA81_RS01345	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYA81_RS01350	COG0436	Aminotransferase
EYA81_RS01395	COG0577	efflux transmembrane transporter activity
EYA81_RS01410	COG0577	efflux transmembrane transporter activity
EYA81_RS01415	COG1136	(ABC) transporter
EYA81_RS01435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS01440	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYA81_RS01445	COG0295	cytidine deaminase activity
EYA81_RS01450	COG0488	(ABC) transporter
EYA81_RS01455	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYA81_RS01485	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EYA81_RS01515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYA81_RS01525	COG0739	heme binding
EYA81_RS01530	COG0686	Belongs to the AlaDH PNT family
EYA81_RS01540	COG0076	glutamate decarboxylase activity
EYA81_RS01545	COG2066	Belongs to the glutaminase family
EYA81_RS01555	COG0531	amino acid
EYA81_RS01580	COG1595	DNA-templated transcription, initiation
EYA81_RS01605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYA81_RS01615	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYA81_RS01630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYA81_RS01635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYA81_RS01645	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS01675	COG0704	Plays a role in the regulation of phosphate uptake
EYA81_RS01680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYA81_RS01685	COG0581	inorganic phosphate transmembrane transporter activity
EYA81_RS01695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYA81_RS01700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYA81_RS01710	COG0586	Pfam SNARE associated Golgi protein
EYA81_RS01715	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EYA81_RS01730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYA81_RS01740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYA81_RS01755	COG0673	inositol 2-dehydrogenase activity
EYA81_RS01795	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYA81_RS01805	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYA81_RS01830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYA81_RS01835	COG0167	dihydroorotate dehydrogenase activity
EYA81_RS01845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYA81_RS01865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYA81_RS01870	COG0497	DNA recombination
EYA81_RS01885	COG0592	DNA-directed DNA polymerase activity
EYA81_RS01900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYA81_RS01900	COG0321	lipoyl(octanoyl) transferase activity
EYA81_RS01920	COG0156	8-amino-7-oxononanoate synthase activity
EYA81_RS01930	COG0019	diaminopimelate decarboxylase activity
EYA81_RS01935	COG0527	aspartate kinase activity
EYA81_RS01940	COG2884	Cell division ATP-binding protein ftsE
EYA81_RS01945	COG0140	phosphoribosyl-ATP diphosphatase activity
EYA81_RS01945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYA81_RS01950	COG0107	imidazoleglycerol-phosphate synthase activity
EYA81_RS01955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYA81_RS01960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYA81_RS01965	COG0788	formyltetrahydrofolate deformylase activity
EYA81_RS01985	COG0561	phosphatase activity
EYA81_RS01990	COG1609	Transcriptional regulator
EYA81_RS01990	COG2207	Transcriptional regulator
EYA81_RS02000	COG0714	Associated with various cellular activities
EYA81_RS02035	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYA81_RS02050	COG1151	hydroxylamine reductase activity
EYA81_RS02075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYA81_RS02080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYA81_RS02090	COG4206	TonB-dependent receptor
EYA81_RS02090	COG1629	transport
EYA81_RS02120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYA81_RS02125	COG1741	Belongs to the pirin family
EYA81_RS02140	COG0346	lactoylglutathione lyase activity
EYA81_RS02170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYA81_RS02170	COG1918	ferrous iron import across plasma membrane
EYA81_RS02175	COG0037	tRNA processing
EYA81_RS02190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYA81_RS02195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYA81_RS02210	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYA81_RS02220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYA81_RS02245	COG4804	nuclease activity
EYA81_RS02310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYA81_RS02425	COG2204	response regulator
EYA81_RS02450	COG2217	Heavy metal translocating P-type atpase
EYA81_RS02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYA81_RS02535	COG1475	DNA binding
EYA81_RS02570	COG4206	TonB-dependent receptor
EYA81_RS02580	COG1741	Belongs to the pirin family
EYA81_RS02585	COG2353	YceI-like domain
EYA81_RS02590	COG1335	isochorismatase
EYA81_RS02595	COG1917	Cupin 2, conserved barrel domain protein
EYA81_RS02595	COG4977	sequence-specific DNA binding
EYA81_RS02600	COG0697	spore germination
EYA81_RS02665	COG3344	reverse transcriptase
EYA81_RS02790	COG4974	Belongs to the 'phage' integrase family
EYA81_RS02800	COG4804	nuclease activity
EYA81_RS02850	COG1193	negative regulation of DNA recombination
EYA81_RS02855	COG1760	l-serine dehydratase
EYA81_RS02870	COG3850	Histidine kinase
EYA81_RS02870	COG5002	protein histidine kinase activity
EYA81_RS02875	COG0745	RESPONSE REGULATOR receiver
EYA81_RS02930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYA81_RS02935	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EYA81_RS02970	COG4139	cobalamin transport
EYA81_RS02990	COG0561	phosphatase activity
EYA81_RS02995	COG0514	ATP-dependent DNA helicase (RecQ)
EYA81_RS03020	COG0443	Heat shock 70 kDa protein
EYA81_RS03045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYA81_RS03050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYA81_RS03065	COG1595	DNA-templated transcription, initiation
EYA81_RS03085	COG2855	membrane
EYA81_RS03090	COG0583	DNA-binding transcription factor activity
EYA81_RS03100	COG0542	response to heat
EYA81_RS03110	COG0237	dephospho-CoA kinase activity
EYA81_RS03120	COG1862	Preprotein translocase
EYA81_RS03125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYA81_RS03135	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYA81_RS03140	COG0193	aminoacyl-tRNA hydrolase activity
EYA81_RS03145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYA81_RS03150	COG0673	inositol 2-dehydrogenase activity
EYA81_RS03155	COG4651	solute:proton antiporter activity
EYA81_RS03155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYA81_RS03160	COG0131	Imidazoleglycerol-phosphate dehydratase
EYA81_RS03165	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYA81_RS03170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYA81_RS03175	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYA81_RS03200	COG4232	protein-disulfide reductase activity
EYA81_RS03210	COG0572	uridine kinase
EYA81_RS03215	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EYA81_RS03220	COG1410	methionine synthase
EYA81_RS03220	COG0646	methionine synthase
EYA81_RS03225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYA81_RS03295	COG2003	Belongs to the UPF0758 family
EYA81_RS03355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYA81_RS03395	COG2801	Transposase and inactivated derivatives
EYA81_RS03415	COG1063	alcohol dehydrogenase
EYA81_RS03460	COG0534	Mate efflux family protein
EYA81_RS03470	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYA81_RS03475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYA81_RS03490	COG2217	Heavy metal translocating P-type atpase
EYA81_RS03520	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS03525	COG2706	6-phosphogluconolactonase activity
EYA81_RS03565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYA81_RS03575	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYA81_RS03585	COG1253	flavin adenine dinucleotide binding
EYA81_RS03615	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
EYA81_RS03620	COG0653	protein targeting
EYA81_RS03650	COG0561	phosphatase activity
EYA81_RS03655	COG4771	TonB-dependent receptor
EYA81_RS03690	COG0525	valine-tRNA ligase activity
EYA81_RS03700	COG3956	TIGRFAM MazG family protein
EYA81_RS03715	COG1595	DNA-templated transcription, initiation
EYA81_RS03760	COG0492	ferredoxin-NADP+ reductase activity
EYA81_RS03770	COG1674	ftsk spoiiie
EYA81_RS03810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYA81_RS03815	COG2211	Major facilitator Superfamily
EYA81_RS03835	COG1136	(ABC) transporter
EYA81_RS03850	COG0490	domain, Protein
EYA81_RS03850	COG0471	metal ion transport
EYA81_RS03865	COG1733	regulation of RNA biosynthetic process
EYA81_RS03885	COG1917	Cupin 2, conserved barrel domain protein
EYA81_RS03885	COG4977	sequence-specific DNA binding
EYA81_RS03900	COG2873	o-acetylhomoserine
EYA81_RS03925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYA81_RS03940	COG0702	epimerase
EYA81_RS03945	COG4771	TonB-dependent receptor
EYA81_RS03960	COG3119	arylsulfatase activity
EYA81_RS03965	COG3537	Alpha-1,2-mannosidase
EYA81_RS03975	COG1940	carbohydrate kinase activity
EYA81_RS03985	COG2188	Transcriptional regulator
EYA81_RS03990	COG0523	cobalamin synthesis protein
EYA81_RS03995	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYA81_RS04000	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYA81_RS04010	COG0194	GDP metabolic process
EYA81_RS04020	COG1214	PFAM Peptidase M22, glycoprotease
EYA81_RS04030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYA81_RS04035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYA81_RS04045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYA81_RS04050	COG0750	zinc metalloprotease
EYA81_RS04055	COG0673	inositol 2-dehydrogenase activity
EYA81_RS04065	COG0632	four-way junction helicase activity
EYA81_RS04075	COG0006	proline dipeptidase activity
EYA81_RS04085	COG1082	Xylose isomerase domain protein TIM barrel
EYA81_RS04105	COG4771	TonB-dependent receptor
EYA81_RS04130	COG4771	TonB-dependent receptor
EYA81_RS04145	COG0363	glucosamine-6-phosphate deaminase activity
EYA81_RS04150	COG1940	carbohydrate kinase activity
EYA81_RS04155	COG3292	Two component regulator propeller
EYA81_RS04155	COG2205	protein histidine kinase activity
EYA81_RS04155	COG0745	RESPONSE REGULATOR receiver
EYA81_RS04165	COG1408	metallophosphoesterase
EYA81_RS04170	COG1575	Belongs to the MenA family. Type 1 subfamily
EYA81_RS04180	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EYA81_RS04190	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYA81_RS04195	COG1082	Xylose isomerase domain protein TIM barrel
EYA81_RS04205	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYA81_RS04210	COG3069	C4-dicarboxylate transmembrane transporter activity
EYA81_RS04220	COG4771	TonB-dependent receptor
EYA81_RS04235	COG0617	tRNA 3'-terminal CCA addition
EYA81_RS04245	COG2204	response regulator
EYA81_RS04250	COG0488	(ABC) transporter
EYA81_RS04255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYA81_RS04290	COG4771	TonB-dependent receptor
EYA81_RS04310	COG1595	DNA-templated transcription, initiation
EYA81_RS04325	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYA81_RS04330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYA81_RS04335	COG1522	sequence-specific DNA binding
EYA81_RS04370	COG0811	peptide transport
EYA81_RS04380	COG0084	hydrolase, TatD family'
EYA81_RS04400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYA81_RS04405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYA81_RS04410	COG0205	6-phosphofructokinase activity
EYA81_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
EYA81_RS04430	COG0372	Belongs to the citrate synthase family
EYA81_RS04445	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EYA81_RS04450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYA81_RS04460	COG0440	acetolactate synthase activity
EYA81_RS04465	COG0028	Belongs to the TPP enzyme family
EYA81_RS04470	COG0129	dihydroxy-acid dehydratase activity
EYA81_RS04475	COG1047	Peptidyl-prolyl cis-trans
EYA81_RS04480	COG3681	Belongs to the UPF0597 family
EYA81_RS04510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYA81_RS04510	COG0551	DNA topoisomerase type I activity
EYA81_RS04520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EYA81_RS04520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EYA81_RS04525	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EYA81_RS04530	COG2985	domain, Protein
EYA81_RS04530	COG0569	domain protein
EYA81_RS04550	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYA81_RS04555	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYA81_RS04560	COG0166	Belongs to the GPI family
EYA81_RS04565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYA81_RS04585	COG0789	Transcriptional regulator
EYA81_RS04595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYA81_RS04605	COG2502	aspartate--ammonia ligase
EYA81_RS04610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYA81_RS04625	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYA81_RS04635	COG0463	Glycosyl transferase, family 2
EYA81_RS04670	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYA81_RS04680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYA81_RS04695	COG1640	4-alpha-glucanotransferase
EYA81_RS04700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYA81_RS04745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYA81_RS04750	COG0318	PFAM AMP-dependent synthetase and ligase
EYA81_RS04760	COG0724	RNA recognition motif
EYA81_RS04775	COG0359	binds to the 23S rRNA
EYA81_RS04780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYA81_RS04785	COG0360	Binds together with S18 to 16S ribosomal RNA
EYA81_RS04805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYA81_RS04820	COG0519	Catalyzes the synthesis of GMP from XMP
EYA81_RS04825	COG3250	beta-galactosidase activity
EYA81_RS04865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYA81_RS04895	COG3279	Response regulator of the LytR AlgR family
EYA81_RS04900	COG3275	phosphorelay sensor kinase activity
EYA81_RS04910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYA81_RS04915	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EYA81_RS04920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYA81_RS04930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EYA81_RS04940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYA81_RS04950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYA81_RS04960	COG0009	L-threonylcarbamoyladenylate synthase
EYA81_RS04970	COG2207	Transcriptional regulator
EYA81_RS04970	COG1609	Transcriptional regulator
EYA81_RS04975	COG2133	pyrroloquinoline quinone binding
EYA81_RS04975	COG5183	chlorophyll binding
EYA81_RS04980	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYA81_RS04995	COG1785	Belongs to the alkaline phosphatase family
EYA81_RS05005	COG3537	Alpha-1,2-mannosidase
EYA81_RS05020	COG0702	epimerase
EYA81_RS05025	COG4206	TonB-dependent receptor
EYA81_RS05025	COG1629	transport
EYA81_RS05035	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS05040	COG3022	response to hydroperoxide
EYA81_RS05050	COG0514	ATP-dependent DNA helicase (RecQ)
EYA81_RS05070	COG0436	Aminotransferase
EYA81_RS05075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYA81_RS05085	COG0358	DNA primase activity
EYA81_RS05090	COG0302	gtp cyclohydrolase
EYA81_RS05100	COG0149	triose-phosphate isomerase activity
EYA81_RS05115	COG0739	heme binding
EYA81_RS05120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYA81_RS05125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYA81_RS05145	COG0811	peptide transport
EYA81_RS05155	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYA81_RS05170	COG4771	TonB-dependent receptor
EYA81_RS05175	COG0702	epimerase
EYA81_RS05180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYA81_RS05190	COG3458	cephalosporin-C deacetylase activity
EYA81_RS05195	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS05200	COG3250	beta-galactosidase activity
EYA81_RS05230	COG4771	TonB-dependent receptor
EYA81_RS05240	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYA81_RS05255	COG0039	L-malate dehydrogenase activity
EYA81_RS05290	COG3118	belongs to the thioredoxin family
EYA81_RS05295	COG0673	inositol 2-dehydrogenase activity
EYA81_RS05315	COG0489	protein tyrosine kinase activity
EYA81_RS05320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYA81_RS05325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYA81_RS05335	COG1570	exodeoxyribonuclease VII activity
EYA81_RS05345	COG0482	sulfurtransferase activity
EYA81_RS05385	COG0582	viral genome integration into host DNA
EYA81_RS05400	COG3507	Belongs to the glycosyl hydrolase 43 family
EYA81_RS05425	COG0702	epimerase
EYA81_RS05430	COG1629	transport
EYA81_RS05465	COG0673	inositol 2-dehydrogenase activity
EYA81_RS05470	COG1408	metallophosphoesterase
EYA81_RS05475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYA81_RS05480	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYA81_RS05485	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EYA81_RS05495	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYA81_RS05500	COG0052	Belongs to the universal ribosomal protein uS2 family
EYA81_RS05505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYA81_RS05510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYA81_RS05520	COG0017	Asparaginyl-tRNA synthetase
EYA81_RS05525	COG1187	pseudouridine synthase activity
EYA81_RS05545	COG0110	maltose O-acetyltransferase activity
EYA81_RS05550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYA81_RS05580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYA81_RS05595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYA81_RS05605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYA81_RS05610	COG0517	IMP dehydrogenase activity
EYA81_RS05610	COG0516	GMP reductase activity
EYA81_RS05615	COG0514	ATP-dependent DNA helicase (RecQ)
EYA81_RS05620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYA81_RS05625	COG0740	serine-type endopeptidase activity
EYA81_RS05630	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYA81_RS05640	COG0724	RNA recognition motif
EYA81_RS05650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYA81_RS05655	COG1127	ABC transporter
EYA81_RS05660	COG1160	GTP binding
EYA81_RS05665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYA81_RS05670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYA81_RS05720	COG4771	TonB-dependent receptor
EYA81_RS05725	COG0702	epimerase
EYA81_RS05750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYA81_RS05755	COG2205	protein histidine kinase activity
EYA81_RS05755	COG2202	Pas domain
EYA81_RS05760	COG2202	Pas domain
EYA81_RS05760	COG2205	protein histidine kinase activity
EYA81_RS05770	COG0436	Aminotransferase
EYA81_RS05775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYA81_RS05830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYA81_RS05870	COG0776	regulation of translation
EYA81_RS05920	COG3119	arylsulfatase activity
EYA81_RS05925	COG0702	epimerase
EYA81_RS05930	COG4771	TonB-dependent receptor
EYA81_RS05965	COG0745	RESPONSE REGULATOR receiver
EYA81_RS05965	COG2205	protein histidine kinase activity
EYA81_RS05965	COG3292	Two component regulator propeller
EYA81_RS05970	COG5434	Belongs to the glycosyl hydrolase 28 family
EYA81_RS06060	COG4771	TonB-dependent receptor
EYA81_RS06080	COG3507	Belongs to the glycosyl hydrolase 43 family
EYA81_RS06090	COG0745	RESPONSE REGULATOR receiver
EYA81_RS06090	COG3292	Two component regulator propeller
EYA81_RS06090	COG2205	protein histidine kinase activity
EYA81_RS06110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYA81_RS06115	COG2205	protein histidine kinase activity
EYA81_RS06115	COG0784	Response regulator, receiver
EYA81_RS06115	COG5002	protein histidine kinase activity
EYA81_RS06135	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS06170	COG1595	DNA-templated transcription, initiation
EYA81_RS06255	COG2207	Transcriptional regulator
EYA81_RS06255	COG4753	response regulator
EYA81_RS06260	COG5002	protein histidine kinase activity
EYA81_RS06265	COG2205	protein histidine kinase activity
EYA81_RS06275	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EYA81_RS06280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYA81_RS06285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYA81_RS06295	COG2204	response regulator
EYA81_RS06300	COG0460	homoserine dehydrogenase
EYA81_RS06300	COG0527	aspartate kinase activity
EYA81_RS06310	COG2942	2-epimerase
EYA81_RS06315	COG2211	Major facilitator Superfamily
EYA81_RS06320	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EYA81_RS06325	COG4124	Belongs to the glycosyl hydrolase 26 family
EYA81_RS06390	COG4206	TonB-dependent receptor
EYA81_RS06390	COG1629	transport
EYA81_RS06395	COG4124	Belongs to the glycosyl hydrolase 26 family
EYA81_RS06410	COG0561	phosphatase activity
EYA81_RS06415	COG4771	TonB-dependent receptor
EYA81_RS06420	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYA81_RS06430	COG3458	cephalosporin-C deacetylase activity
EYA81_RS06435	COG2207	Transcriptional regulator
EYA81_RS06435	COG0662	Cupin 2, conserved barrel domain protein
EYA81_RS06440	COG3250	beta-galactosidase activity
EYA81_RS06445	COG3459	Glycosyltransferase 36 associated
EYA81_RS06450	COG0667	Aldo Keto reductase
EYA81_RS06455	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS06470	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS06475	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS06480	COG0737	Belongs to the 5'-nucleotidase family
EYA81_RS06485	COG0737	Belongs to the 5'-nucleotidase family
EYA81_RS06490	COG0335	large ribosomal subunit rRNA binding
EYA81_RS06495	COG1940	carbohydrate kinase activity
EYA81_RS06500	COG1136	(ABC) transporter
EYA81_RS06505	COG1136	(ABC) transporter
EYA81_RS06505	COG0577	efflux transmembrane transporter activity
EYA81_RS06510	COG0577	efflux transmembrane transporter activity
EYA81_RS06510	COG1136	(ABC) transporter
EYA81_RS06515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS06535	COG2996	Protein conserved in bacteria
EYA81_RS06540	COG0039	L-malate dehydrogenase activity
EYA81_RS06565	COG0137	argininosuccinate synthase activity
EYA81_RS06575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYA81_RS06580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYA81_RS06585	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYA81_RS06590	COG1396	sequence-specific DNA binding
EYA81_RS06590	COG1917	Cupin 2, conserved barrel domain protein
EYA81_RS06595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYA81_RS06615	COG0165	Argininosuccinate lyase
EYA81_RS06625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYA81_RS06635	COG2890	protein-(glutamine-N5) methyltransferase activity
EYA81_RS06640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYA81_RS06640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYA81_RS06650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYA81_RS06670	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EYA81_RS06680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYA81_RS06685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYA81_RS06715	COG0564	pseudouridine synthase activity
EYA81_RS06725	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EYA81_RS06730	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYA81_RS06735	COG1216	Glycosyl transferase, family 2
EYA81_RS06740	COG2003	Belongs to the UPF0758 family
EYA81_RS06750	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYA81_RS06765	COG1785	Belongs to the alkaline phosphatase family
EYA81_RS06770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYA81_RS06775	COG0280	phosphate acetyltransferase
EYA81_RS06785	COG1380	Effector of murein hydrolase LrgA
EYA81_RS06790	COG1346	cytolysis
EYA81_RS06805	COG0312	modulator of DNA gyrase
EYA81_RS06810	COG0312	modulator of DNA gyrase
EYA81_RS06815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYA81_RS06820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYA81_RS06825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYA81_RS06835	COG0733	neurotransmitter:sodium symporter activity
EYA81_RS06845	COG1136	(ABC) transporter
EYA81_RS06850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYA81_RS06855	COG0589	response to stress
EYA81_RS06855	COG0475	glutathione-regulated potassium exporter activity
EYA81_RS06860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYA81_RS06865	COG0702	epimerase
EYA81_RS06870	COG4206	TonB-dependent receptor
EYA81_RS06870	COG1629	transport
EYA81_RS06880	COG1629	transport
EYA81_RS06880	COG4206	TonB-dependent receptor
EYA81_RS06885	COG0702	epimerase
EYA81_RS06920	COG3876	Protein conserved in bacteria
EYA81_RS06925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYA81_RS06955	COG2807	transmembrane transport
EYA81_RS06960	COG3876	Protein conserved in bacteria
EYA81_RS06980	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EYA81_RS06985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYA81_RS06995	COG0423	glycine-tRNA ligase activity
EYA81_RS07000	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYA81_RS07015	COG0745	RESPONSE REGULATOR receiver
EYA81_RS07015	COG2205	protein histidine kinase activity
EYA81_RS07015	COG3292	Two component regulator propeller
EYA81_RS07020	COG4771	TonB-dependent receptor
EYA81_RS07025	COG0561	phosphatase activity
EYA81_RS07040	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS07045	COG3250	beta-galactosidase activity
EYA81_RS07050	COG1874	Beta-galactosidase
EYA81_RS07055	COG3250	beta-galactosidase activity
EYA81_RS07065	COG1501	Belongs to the glycosyl hydrolase 31 family
EYA81_RS07070	COG3507	Belongs to the glycosyl hydrolase 43 family
EYA81_RS07105	COG1629	transport
EYA81_RS07105	COG4206	TonB-dependent receptor
EYA81_RS07130	COG4771	TonB-dependent receptor
EYA81_RS07135	COG0702	epimerase
EYA81_RS07140	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS07165	COG2954	triphosphatase activity
EYA81_RS07170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EYA81_RS07205	COG4206	TonB-dependent receptor
EYA81_RS07205	COG1629	transport
EYA81_RS07210	COG1022	Amp-dependent synthetase and ligase
EYA81_RS07220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYA81_RS07225	COG4942	peptidase
EYA81_RS07240	COG0756	dUTP diphosphatase activity
EYA81_RS07275	COG2001	Belongs to the MraZ family
EYA81_RS07290	COG0768	penicillin binding
EYA81_RS07295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYA81_RS07300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYA81_RS07305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYA81_RS07310	COG0772	Belongs to the SEDS family
EYA81_RS07315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYA81_RS07320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYA81_RS07330	COG0849	cell division
EYA81_RS07335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYA81_RS07340	COG1610	YqeY-like protein
EYA81_RS07345	COG1381	Involved in DNA repair and RecF pathway recombination
EYA81_RS07355	COG0268	Binds directly to 16S ribosomal RNA
EYA81_RS07360	COG0187	DNA topoisomerase II activity
EYA81_RS07370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYA81_RS07380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYA81_RS07390	COG1629	transport
EYA81_RS07390	COG4206	TonB-dependent receptor
EYA81_RS07405	COG2431	L-lysine efflux transmembrane transporter activity
EYA81_RS07410	COG3250	beta-galactosidase activity
EYA81_RS07415	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EYA81_RS07415	COG3408	Glycogen debranching enzyme
EYA81_RS07420	COG3426	butyrate kinase activity
EYA81_RS07425	COG0280	phosphate acetyltransferase
EYA81_RS07440	COG2166	iron-sulfur cluster assembly
EYA81_RS07445	COG3655	Transcriptional regulator
EYA81_RS07475	COG1266	CAAX protease self-immunity
EYA81_RS07485	COG0196	riboflavin kinase activity
EYA81_RS07490	COG1011	Hydrolase
EYA81_RS07495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYA81_RS07505	COG1773	rubredoxin
EYA81_RS07510	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYA81_RS07515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYA81_RS07520	COG2205	protein histidine kinase activity
EYA81_RS07525	COG0006	proline dipeptidase activity
EYA81_RS07540	COG0509	glycine decarboxylation via glycine cleavage system
EYA81_RS07545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYA81_RS07550	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYA81_RS07555	COG2066	Belongs to the glutaminase family
EYA81_RS07575	COG3119	arylsulfatase activity
EYA81_RS07600	COG0702	epimerase
EYA81_RS07605	COG4771	TonB-dependent receptor
EYA81_RS07630	COG0793	Belongs to the peptidase S41A family
EYA81_RS07635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYA81_RS07655	COG1040	competence protein
EYA81_RS07660	COG0483	inositol monophosphate 1-phosphatase activity
EYA81_RS07670	COG0515	serine threonine protein kinase
EYA81_RS07670	COG1357	PFAM Pentapeptide repeats (8 copies)
EYA81_RS07705	COG0515	serine threonine protein kinase
EYA81_RS07705	COG2815	serine threonine protein kinase
EYA81_RS07710	COG0515	serine threonine protein kinase
EYA81_RS07715	COG0515	serine threonine protein kinase
EYA81_RS07715	COG2815	serine threonine protein kinase
EYA81_RS07750	COG0631	protein serine/threonine phosphatase activity
EYA81_RS07760	COG2176	DNA-directed DNA polymerase activity
EYA81_RS07765	COG2816	NAD+ diphosphatase activity
EYA81_RS07785	COG0018	arginyl-trna synthetase
EYA81_RS07805	COG0708	Exodeoxyribonuclease III
EYA81_RS07810	COG0339	signal peptide processing
EYA81_RS07815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYA81_RS07835	COG0674	pyruvate-flavodoxin oxidoreductase activity
EYA81_RS07835	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EYA81_RS07840	COG1013	pyruvate-flavodoxin oxidoreductase activity
EYA81_RS07850	COG4206	TonB-dependent receptor
EYA81_RS07850	COG1629	transport
EYA81_RS07880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYA81_RS07885	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EYA81_RS07895	COG1217	gtp-binding protein TYPA
EYA81_RS07900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYA81_RS07925	COG0318	PFAM AMP-dependent synthetase and ligase
EYA81_RS07930	COG1854	S-ribosylhomocysteine lyase activity
EYA81_RS07935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYA81_RS07945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYA81_RS07950	COG4591	ABC-type transport system involved in lipoprotein release permease component
EYA81_RS07965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYA81_RS07970	COG4974	Belongs to the 'phage' integrase family
EYA81_RS07985	COG0606	chelatase, subunit chli
EYA81_RS07995	COG3594	Acyltransferase
EYA81_RS08015	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYA81_RS08015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYA81_RS08030	COG3475	LICD family
EYA81_RS08040	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS08050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYA81_RS08055	COG0545	Peptidyl-prolyl cis-trans isomerase
EYA81_RS08060	COG0545	Peptidyl-prolyl cis-trans isomerase
EYA81_RS08065	COG1522	sequence-specific DNA binding
EYA81_RS08115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYA81_RS08120	COG3250	beta-galactosidase activity
EYA81_RS08130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYA81_RS08150	COG2755	lipolytic protein G-D-S-L family
EYA81_RS08150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYA81_RS08170	COG0702	epimerase
EYA81_RS08175	COG4206	TonB-dependent receptor
EYA81_RS08175	COG1629	transport
EYA81_RS08190	COG2814	Major facilitator Superfamily
EYA81_RS08205	COG1940	carbohydrate kinase activity
EYA81_RS08215	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EYA81_RS08215	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EYA81_RS08260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYA81_RS08265	COG3409	Peptidoglycan-binding domain 1 protein
EYA81_RS08265	COG0793	Belongs to the peptidase S41A family
EYA81_RS08270	COG0671	phosphoesterase, PA-phosphatase related
EYA81_RS08285	COG1053	succinate dehydrogenase
EYA81_RS08290	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYA81_RS08330	COG0826	peptidase U32
EYA81_RS08335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYA81_RS08360	COG0557	exoribonuclease II activity
EYA81_RS08375	COG1045	serine acetyltransferase
EYA81_RS08380	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYA81_RS08380	COG0116	Belongs to the methyltransferase superfamily
EYA81_RS08385	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS08385	COG1506	peptidase
EYA81_RS08390	COG0151	Belongs to the GarS family
EYA81_RS08400	COG1238	metal cluster binding
EYA81_RS08430	COG2942	2-epimerase
EYA81_RS08440	COG4206	TonB-dependent receptor
EYA81_RS08440	COG1629	transport
EYA81_RS08445	COG1501	Belongs to the glycosyl hydrolase 31 family
EYA81_RS08465	COG3291	Pkd domain containing protein
EYA81_RS08475	COG2942	2-epimerase
EYA81_RS08490	COG2076	Multidrug Resistance protein
EYA81_RS08505	COG1373	ATPase (AAA superfamily
EYA81_RS08530	COG4585	Histidine kinase
EYA81_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
EYA81_RS08550	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EYA81_RS08575	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYA81_RS08605	COG4974	Belongs to the 'phage' integrase family
EYA81_RS08615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYA81_RS08620	COG0084	hydrolase, TatD family'
EYA81_RS08625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYA81_RS08630	COG0594	ribonuclease P activity
EYA81_RS08645	COG1611	Belongs to the LOG family
EYA81_RS08655	COG2205	protein histidine kinase activity
EYA81_RS08710	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYA81_RS08740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYA81_RS08740	COG2198	Histidine kinase
EYA81_RS08740	COG2205	protein histidine kinase activity
EYA81_RS08740	COG0784	Response regulator, receiver
EYA81_RS08775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYA81_RS08780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYA81_RS08780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYA81_RS08785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYA81_RS08790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYA81_RS08795	COG1968	undecaprenyl-diphosphatase activity
EYA81_RS08805	COG2177	Part of the ABC transporter FtsEX involved in
EYA81_RS08810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYA81_RS08820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYA81_RS08830	COG0427	acetyl-CoA hydrolase
EYA81_RS08905	COG3279	Response regulator of the LytR AlgR family
EYA81_RS08920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EYA81_RS08925	COG1592	Rubrerythrin
EYA81_RS08930	COG0659	secondary active sulfate transmembrane transporter activity
EYA81_RS08945	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYA81_RS08945	COG0731	radical SAM domain protein
EYA81_RS08955	COG1476	TRANSCRIPTIONal
EYA81_RS08975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYA81_RS08980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYA81_RS08985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYA81_RS08990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYA81_RS08995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYA81_RS09000	COG0495	leucyl-tRNA aminoacylation
EYA81_RS09005	COG0697	spore germination
EYA81_RS09020	COG4771	TonB-dependent receptor
EYA81_RS09040	COG4206	TonB-dependent receptor
EYA81_RS09040	COG1629	transport
EYA81_RS09065	COG0738	Major facilitator superfamily
EYA81_RS09080	COG1609	Transcriptional regulator
EYA81_RS09105	COG4771	TonB-dependent receptor
EYA81_RS09135	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS09150	COG4771	TonB-dependent receptor
EYA81_RS09175	COG0383	alpha-mannosidase activity
EYA81_RS09185	COG5002	protein histidine kinase activity
EYA81_RS09195	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYA81_RS09240	COG3250	beta-galactosidase activity
EYA81_RS09245	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09245	COG3292	Two component regulator propeller
EYA81_RS09245	COG2205	protein histidine kinase activity
EYA81_RS09250	COG4948	Mandelate Racemase Muconate Lactonizing
EYA81_RS09275	COG4206	TonB-dependent receptor
EYA81_RS09275	COG1629	transport
EYA81_RS09280	COG0702	epimerase
EYA81_RS09300	COG3408	Glycogen debranching enzyme
EYA81_RS09305	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS09310	COG1501	Belongs to the glycosyl hydrolase 31 family
EYA81_RS09315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYA81_RS09330	COG0012	GTP binding
EYA81_RS09350	COG1629	transport
EYA81_RS09365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYA81_RS09365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYA81_RS09370	COG0142	geranyltranstransferase activity
EYA81_RS09375	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYA81_RS09380	COG1694	Mazg nucleotide pyrophosphohydrolase
EYA81_RS09385	COG1490	D-aminoacyl-tRNA deacylase activity
EYA81_RS09390	COG0322	excinuclease ABC activity
EYA81_RS09395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYA81_RS09410	COG3292	Two component regulator propeller
EYA81_RS09410	COG2205	protein histidine kinase activity
EYA81_RS09410	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09410	COG3292	Two component regulator propeller
EYA81_RS09410	COG2205	protein histidine kinase activity
EYA81_RS09410	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09415	COG4206	TonB-dependent receptor
EYA81_RS09415	COG1629	transport
EYA81_RS09450	COG3408	Glycogen debranching enzyme
EYA81_RS09460	COG2017	converts alpha-aldose to the beta-anomer
EYA81_RS09470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYA81_RS09475	COG2715	membrane protein required for spore maturation
EYA81_RS09480	COG2234	aminopeptidase activity
EYA81_RS09490	COG2255	four-way junction helicase activity
EYA81_RS09505	COG3591	Belongs to the peptidase S1B family
EYA81_RS09510	COG3634	alkyl hydroperoxide reductase activity
EYA81_RS09520	COG0583	DNA-binding transcription factor activity
EYA81_RS09525	COG0783	Belongs to the Dps family
EYA81_RS09540	COG4176	ABC-type proline glycine betaine transport system permease component
EYA81_RS09545	COG2113	Glycine betaine
EYA81_RS09590	COG0513	Belongs to the DEAD box helicase family
EYA81_RS09600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYA81_RS09605	COG0517	IMP dehydrogenase activity
EYA81_RS09605	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EYA81_RS09610	COG0612	Peptidase, M16
EYA81_RS09620	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYA81_RS09635	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYA81_RS09640	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS09645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EYA81_RS09650	COG1312	Catalyzes the dehydration of D-mannonate
EYA81_RS09655	COG1028	Short-chain dehydrogenase reductase Sdr
EYA81_RS09665	COG0681	Belongs to the peptidase S26 family
EYA81_RS09670	COG0681	Belongs to the peptidase S26 family
EYA81_RS09675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYA81_RS09695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYA81_RS09700	COG5492	domain, Protein
EYA81_RS09710	COG0702	epimerase
EYA81_RS09715	COG4771	TonB-dependent receptor
EYA81_RS09720	COG3119	arylsulfatase activity
EYA81_RS09725	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09725	COG2205	protein histidine kinase activity
EYA81_RS09725	COG3292	Two component regulator propeller
EYA81_RS09725	COG2205	protein histidine kinase activity
EYA81_RS09725	COG0745	RESPONSE REGULATOR receiver
EYA81_RS09725	COG3292	Two component regulator propeller
EYA81_RS09750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYA81_RS09765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS09785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYA81_RS09790	COG3119	arylsulfatase activity
EYA81_RS09805	COG0482	sulfurtransferase activity
EYA81_RS09815	COG0205	6-phosphofructokinase activity
EYA81_RS09820	COG0571	ribonuclease III activity
EYA81_RS09825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYA81_RS09830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYA81_RS09835	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYA81_RS09840	COG3083	sulfuric ester hydrolase activity
EYA81_RS09845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYA81_RS09855	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS09860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYA81_RS09865	COG4750	Nucleotidyl transferase
EYA81_RS09870	COG3475	LICD family
EYA81_RS09890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EYA81_RS09890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYA81_RS09895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EYA81_RS09900	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EYA81_RS09910	COG1368	sulfuric ester hydrolase activity
EYA81_RS09920	COG1442	glycosyl transferase family 8
EYA81_RS09920	COG1216	Glycosyl transferase, family 2
EYA81_RS09925	COG3754	Rhamnan synthesis protein F
EYA81_RS09945	COG1215	transferase activity, transferring glycosyl groups
EYA81_RS09960	COG1132	(ABC) transporter
EYA81_RS09965	COG1132	(ABC) transporter
EYA81_RS09975	COG0673	inositol 2-dehydrogenase activity
EYA81_RS09990	COG0328	RNA-DNA hybrid ribonuclease activity
EYA81_RS09990	COG3341	Caulimovirus viroplasmin
EYA81_RS10000	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYA81_RS10005	COG1166	arginine decarboxylase activity
EYA81_RS10010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYA81_RS10015	COG1595	DNA-templated transcription, initiation
EYA81_RS10040	COG0745	RESPONSE REGULATOR receiver
EYA81_RS10040	COG2205	protein histidine kinase activity
EYA81_RS10040	COG3292	Two component regulator propeller
EYA81_RS10045	COG2272	Belongs to the type-B carboxylesterase lipase family
EYA81_RS10050	COG4771	TonB-dependent receptor
EYA81_RS10080	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS10085	COG3693	PFAM glycoside hydrolase, family 10
EYA81_RS10085	COG3507	Belongs to the glycosyl hydrolase 43 family
EYA81_RS10085	COG2382	esterase
EYA81_RS10090	COG2382	esterase
EYA81_RS10095	COG2382	esterase
EYA81_RS10100	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS10105	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS10110	COG0779	Required for maturation of 30S ribosomal subunits
EYA81_RS10115	COG0195	Participates in both transcription termination and antitermination
EYA81_RS10120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYA81_RS10130	COG0719	Fe-S assembly protein
EYA81_RS10135	COG0396	ATPase activity
EYA81_RS10140	COG0719	Fe-S assembly protein
EYA81_RS10145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYA81_RS10150	COG0393	Putative heavy-metal-binding
EYA81_RS10155	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYA81_RS10165	COG4206	TonB-dependent receptor
EYA81_RS10165	COG1629	transport
EYA81_RS10180	COG1185	polyribonucleotide nucleotidyltransferase activity
EYA81_RS10190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYA81_RS10195	COG0537	adenosine 5'-monophosphoramidase activity
EYA81_RS10200	COG0662	Cupin 2, conserved barrel domain protein
EYA81_RS10200	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EYA81_RS10280	COG4771	TonB-dependent receptor
EYA81_RS10300	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYA81_RS10305	COG2205	protein histidine kinase activity
EYA81_RS10305	COG0745	RESPONSE REGULATOR receiver
EYA81_RS10305	COG3292	Two component regulator propeller
EYA81_RS10310	COG1501	Belongs to the glycosyl hydrolase 31 family
EYA81_RS10315	COG3250	beta-galactosidase activity
EYA81_RS10320	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS10340	COG2096	Adenosyltransferase
EYA81_RS10350	COG0514	ATP-dependent DNA helicase (RecQ)
EYA81_RS10440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYA81_RS10445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYA81_RS10470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYA81_RS10480	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYA81_RS10485	COG0006	proline dipeptidase activity
EYA81_RS10490	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYA81_RS10495	COG4974	Belongs to the 'phage' integrase family
EYA81_RS10540	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYA81_RS10545	COG0081	regulation of translation
EYA81_RS10550	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYA81_RS10555	COG0222	ribosome binding
EYA81_RS10560	COG0085	RNA polymerase activity
EYA81_RS10565	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYA81_RS10575	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYA81_RS10580	COG0049	tRNA binding
EYA81_RS10585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYA81_RS10590	COG0051	transcription antitermination factor activity, RNA binding
EYA81_RS10595	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYA81_RS10600	COG0088	Forms part of the polypeptide exit tunnel
EYA81_RS10605	COG0089	rRNA binding
EYA81_RS10610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYA81_RS10615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYA81_RS10620	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYA81_RS10625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYA81_RS10630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYA81_RS10635	COG0255	Belongs to the universal ribosomal protein uL29 family
EYA81_RS10640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYA81_RS10645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYA81_RS10650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYA81_RS10655	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYA81_RS10660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYA81_RS10665	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYA81_RS10670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYA81_RS10675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYA81_RS10680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYA81_RS10685	COG1841	ribosomal large subunit assembly
EYA81_RS10690	COG0200	Binds to the 23S rRNA
EYA81_RS10705	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYA81_RS10710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYA81_RS10715	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYA81_RS10720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYA81_RS10725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYA81_RS10730	COG0202	RNA polymerase activity
EYA81_RS10735	COG0203	ribosomal protein L17
EYA81_RS10750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYA81_RS10765	COG2431	L-lysine efflux transmembrane transporter activity
EYA81_RS10785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYA81_RS10795	COG1228	amidohydrolase
EYA81_RS10805	COG2986	histidine ammonia-lyase
EYA81_RS10810	COG1309	transcriptional regulator
EYA81_RS10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS10845	COG1696	Membrane protein involved in D-alanine export
EYA81_RS10850	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYA81_RS10945	COG1131	(ABC) transporter
EYA81_RS10965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EYA81_RS10985	COG0564	pseudouridine synthase activity
EYA81_RS10990	COG1506	peptidase
EYA81_RS10990	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS11000	COG2204	response regulator
EYA81_RS11005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYA81_RS11010	COG0612	Peptidase, M16
EYA81_RS11015	COG0534	Mate efflux family protein
EYA81_RS11020	COG0784	Response regulator, receiver
EYA81_RS11020	COG2205	protein histidine kinase activity
EYA81_RS11065	COG0488	(ABC) transporter
EYA81_RS11070	COG3590	peptidase
EYA81_RS11075	COG0138	bifunctional purine biosynthesis protein purh
EYA81_RS11085	COG1792	Involved in formation and maintenance of cell shape
EYA81_RS11100	COG0772	Belongs to the SEDS family
EYA81_RS11110	COG1774	PSP1 C-terminal conserved region
EYA81_RS11115	COG0470	DNA polymerase III
EYA81_RS11120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYA81_RS11135	COG0826	peptidase U32
EYA81_RS11145	COG4771	TonB-dependent receptor
EYA81_RS11155	COG2205	protein histidine kinase activity
EYA81_RS11155	COG3292	Two component regulator propeller
EYA81_RS11155	COG0745	RESPONSE REGULATOR receiver
EYA81_RS11155	COG3292	Two component regulator propeller
EYA81_RS11155	COG2205	protein histidine kinase activity
EYA81_RS11155	COG0745	RESPONSE REGULATOR receiver
EYA81_RS11160	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EYA81_RS11165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYA81_RS11170	COG0288	reversible hydration of carbon dioxide
EYA81_RS11175	COG0252	asparaginase activity
EYA81_RS11185	COG0460	homoserine dehydrogenase
EYA81_RS11185	COG0527	aspartate kinase activity
EYA81_RS11190	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
EYA81_RS11195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYA81_RS11270	COG0628	permease
EYA81_RS11275	COG1435	thymidine kinase activity
EYA81_RS11285	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYA81_RS11300	COG2095	MarC family integral membrane protein
EYA81_RS11310	COG1629	transport
EYA81_RS11310	COG4206	TonB-dependent receptor
EYA81_RS11315	COG1373	ATPase (AAA superfamily
EYA81_RS11330	COG4771	TonB-dependent receptor
EYA81_RS11340	COG4206	TonB-dependent receptor
EYA81_RS11340	COG1629	transport
EYA81_RS11355	COG1629	transport
EYA81_RS11365	COG1629	transport
EYA81_RS11365	COG4206	TonB-dependent receptor
EYA81_RS11380	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYA81_RS11390	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EYA81_RS11390	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EYA81_RS11405	COG0531	amino acid
EYA81_RS11415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYA81_RS11420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYA81_RS11425	COG1162	GTPase activity
EYA81_RS11430	COG0233	cytoplasmic translational termination
EYA81_RS11435	COG0528	UMP kinase activity
EYA81_RS11445	COG0697	spore germination
EYA81_RS11450	COG2217	Heavy metal translocating P-type atpase
EYA81_RS11455	COG0534	Mate efflux family protein
EYA81_RS11510	COG0792	nuclease activity
EYA81_RS11535	COG1183	phosphatidylcholine synthase activity
EYA81_RS11540	COG0688	phosphatidylethanolamine metabolic process
EYA81_RS11570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYA81_RS11580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYA81_RS11590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYA81_RS11600	COG2985	domain, Protein
EYA81_RS11600	COG0490	domain, Protein
EYA81_RS11605	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS11605	COG4946	Tricorn protease homolog
EYA81_RS11605	COG1506	peptidase
EYA81_RS11630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYA81_RS11645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYA81_RS11650	COG0742	ribosomal rna small subunit methyltransferase
EYA81_RS11680	COG0739	heme binding
EYA81_RS11690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYA81_RS11695	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYA81_RS11695	COG1388	LysM domain
EYA81_RS11705	COG1475	DNA binding
EYA81_RS11710	COG1192	Involved in chromosome partitioning
EYA81_RS11725	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYA81_RS11730	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYA81_RS11745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYA81_RS11760	COG0138	bifunctional purine biosynthesis protein purh
EYA81_RS11765	COG1196	nuclear chromosome segregation
EYA81_RS11770	COG2239	Acts as a magnesium transporter
EYA81_RS11775	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYA81_RS11785	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYA81_RS11795	COG1203	CRISPR-associated helicase, Cas3
EYA81_RS11820	COG1518	maintenance of DNA repeat elements
EYA81_RS11825	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EYA81_RS11850	COG1119	ATPase activity
EYA81_RS11860	COG0668	transmembrane transport
EYA81_RS11880	COG1404	Belongs to the peptidase S8 family
EYA81_RS11880	COG4412	M6 family metalloprotease domain protein
EYA81_RS11885	COG5002	protein histidine kinase activity
EYA81_RS11885	COG0784	Response regulator, receiver
EYA81_RS11885	COG2205	protein histidine kinase activity
EYA81_RS11895	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYA81_RS11900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYA81_RS11905	COG0713	ATP synthesis coupled electron transport
EYA81_RS11910	COG0839	Belongs to the complex I subunit 6 family
EYA81_RS11915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYA81_RS11920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYA81_RS11925	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYA81_RS11925	COG0649	NAD binding
EYA81_RS11930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYA81_RS11935	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYA81_RS11945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYA81_RS11950	COG0569	domain protein
EYA81_RS11955	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYA81_RS11970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYA81_RS11975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYA81_RS11980	COG0805	protein transport
EYA81_RS11995	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EYA81_RS12000	COG3775	system Galactitol-specific IIC component
EYA81_RS12005	COG0546	phosphoglycolate phosphatase activity
EYA81_RS12015	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYA81_RS12020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYA81_RS12030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYA81_RS12035	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS12035	COG1506	peptidase
EYA81_RS12040	COG4821	SIS domain
EYA81_RS12055	COG1242	4 iron, 4 sulfur cluster binding
EYA81_RS12065	COG0363	glucosamine-6-phosphate deaminase activity
EYA81_RS12125	COG0628	permease
EYA81_RS12130	COG0009	L-threonylcarbamoyladenylate synthase
EYA81_RS12135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYA81_RS12140	COG0561	phosphatase activity
EYA81_RS12155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYA81_RS12170	COG1472	Belongs to the glycosyl hydrolase 3 family
EYA81_RS12180	COG1073	alpha beta
EYA81_RS12200	COG3487	Iron-regulated protein
EYA81_RS12225	COG1333	cytochrome c biogenesis protein
EYA81_RS12225	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYA81_RS12250	COG1629	transport
EYA81_RS12250	COG4206	TonB-dependent receptor
EYA81_RS12265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYA81_RS12275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYA81_RS12280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EYA81_RS12280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYA81_RS12285	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYA81_RS12290	COG1078	dGTPase activity
EYA81_RS12295	COG0284	orotidine-5'-phosphate decarboxylase activity
EYA81_RS12300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYA81_RS12305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYA81_RS12310	COG1704	LemA family
EYA81_RS12325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYA81_RS12330	COG2226	methyltransferase
EYA81_RS12335	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYA81_RS12340	COG1702	phosphate starvation-inducible protein PhoH
EYA81_RS12355	COG1496	oxidoreductase activity
EYA81_RS12360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYA81_RS12365	COG0563	adenylate kinase activity
EYA81_RS12370	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYA81_RS12380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYA81_RS12380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYA81_RS12390	COG0101	tRNA pseudouridine synthase activity
EYA81_RS12400	COG1956	GAF domain-containing protein
EYA81_RS12410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYA81_RS12420	COG2755	lipolytic protein G-D-S-L family
EYA81_RS12420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYA81_RS12495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYA81_RS12520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYA81_RS12525	COG0793	Belongs to the peptidase S41A family
EYA81_RS12530	COG2131	deaminase
EYA81_RS12540	COG0339	signal peptide processing
EYA81_RS12550	COG1970	mechanosensitive ion channel activity
EYA81_RS12560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYA81_RS12560	COG0519	Catalyzes the synthesis of GMP from XMP
EYA81_RS12565	COG0519	Catalyzes the synthesis of GMP from XMP
EYA81_RS12590	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS12605	COG0297	glycogen (starch) synthase activity
EYA81_RS12610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYA81_RS12615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYA81_RS12625	COG0543	2 iron, 2 sulfur cluster binding
EYA81_RS12640	COG3279	Response regulator of the LytR AlgR family
EYA81_RS12645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYA81_RS12650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYA81_RS12655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYA81_RS12675	COG1191	sigma factor activity
EYA81_RS12685	COG3537	Alpha-1,2-mannosidase
EYA81_RS12690	COG4771	TonB-dependent receptor
EYA81_RS12715	COG3537	Alpha-1,2-mannosidase
EYA81_RS12735	COG1629	transport
EYA81_RS12735	COG4206	TonB-dependent receptor
EYA81_RS12755	COG3537	Alpha-1,2-mannosidase
EYA81_RS12765	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EYA81_RS12770	COG3537	Alpha-1,2-mannosidase
EYA81_RS12785	COG0791	NLP P60 protein
EYA81_RS12800	COG0612	Peptidase, M16
EYA81_RS12805	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYA81_RS12810	COG1597	lipid kinase activity
EYA81_RS12815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYA81_RS12835	COG3973	AAA domain
EYA81_RS12885	COG0326	Molecular chaperone. Has ATPase activity
EYA81_RS13055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYA81_RS13055	COG0551	DNA topoisomerase type I activity
EYA81_RS13080	COG0784	Response regulator, receiver
EYA81_RS13080	COG2205	protein histidine kinase activity
EYA81_RS13095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYA81_RS13135	COG3209	COG3209 Rhs family protein
EYA81_RS13160	COG3209	COG3209 Rhs family protein
EYA81_RS13190	COG0542	response to heat
EYA81_RS13325	COG1192	Involved in chromosome partitioning
EYA81_RS13435	COG4932	domain protein
EYA81_RS13435	COG1388	LysM domain
EYA81_RS13580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYA81_RS13585	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYA81_RS13590	COG1663	tetraacyldisaccharide 4'-kinase activity
EYA81_RS13595	COG0616	signal peptide processing
EYA81_RS13635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYA81_RS13640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYA81_RS13645	COG0066	3-isopropylmalate dehydratase activity
EYA81_RS13665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYA81_RS13675	COG0514	ATP-dependent DNA helicase (RecQ)
EYA81_RS13695	COG0735	belongs to the Fur family
EYA81_RS13700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYA81_RS13715	COG0124	histidyl-tRNA synthetase
EYA81_RS13730	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYA81_RS13735	COG0459	protein refolding
EYA81_RS13755	COG0484	heat shock protein binding
EYA81_RS13775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EYA81_RS13780	COG2086	electron transfer activity
EYA81_RS13795	COG4667	esterase of the alpha-beta hydrolase superfamily
EYA81_RS13800	COG4771	TonB-dependent receptor
EYA81_RS13810	COG1621	beta-fructofuranosidase activity
EYA81_RS13815	COG1621	beta-fructofuranosidase activity
EYA81_RS13820	COG1621	beta-fructofuranosidase activity
EYA81_RS13840	COG0745	RESPONSE REGULATOR receiver
EYA81_RS13840	COG3292	Two component regulator propeller
EYA81_RS13840	COG2205	protein histidine kinase activity
EYA81_RS13865	COG1649	PFAM Uncharacterised BCR, COG1649
EYA81_RS13870	COG1966	Carbon starvation protein
EYA81_RS13895	COG1649	PFAM Uncharacterised BCR, COG1649
EYA81_RS13910	COG0745	RESPONSE REGULATOR receiver
EYA81_RS13910	COG3292	Two component regulator propeller
EYA81_RS13910	COG2205	protein histidine kinase activity
EYA81_RS13925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EYA81_RS13930	COG1280	lysine exporter protein (LysE YggA)
EYA81_RS13945	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYA81_RS13995	COG0511	ligase activity, forming carbon-carbon bonds
EYA81_RS14010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYA81_RS14015	COG1566	PFAM secretion protein HlyD family protein
EYA81_RS14020	COG1554	hydrolase, family 65, central catalytic
EYA81_RS14030	COG1609	Transcriptional regulator
EYA81_RS14040	COG3250	beta-galactosidase activity
EYA81_RS14045	COG1629	transport
EYA81_RS14045	COG4206	TonB-dependent receptor
EYA81_RS14065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EYA81_RS14095	COG0778	Nitroreductase
EYA81_RS14110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EYA81_RS14115	COG0424	maF-like protein
EYA81_RS14130	COG0126	phosphoglycerate kinase activity
EYA81_RS14135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYA81_RS14145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYA81_RS14155	COG1629	transport
EYA81_RS14165	COG2223	nitrite transmembrane transporter activity
EYA81_RS14225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYA81_RS14230	COG1523	belongs to the glycosyl hydrolase 13 family
EYA81_RS14235	COG1119	ATPase activity
EYA81_RS14250	COG0671	phosphoesterase, PA-phosphatase related
EYA81_RS14265	COG5002	protein histidine kinase activity
EYA81_RS14270	COG0745	RESPONSE REGULATOR receiver
EYA81_RS14275	COG0668	transmembrane transport
EYA81_RS14285	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYA81_RS14300	COG3142	Participates in the control of copper homeostasis
EYA81_RS14305	COG1418	mRNA catabolic process
EYA81_RS14340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYA81_RS14345	COG2832	Protein of unknown function (DUF454)
EYA81_RS14350	COG0351	phosphomethylpyrimidine kinase
EYA81_RS14365	COG0602	queuosine metabolic process
EYA81_RS14380	COG1509	lysine 2,3-aminomutase activity
EYA81_RS14415	COG0741	lytic transglycosylase activity
EYA81_RS14415	COG1388	LysM domain
EYA81_RS14430	COG0784	Response regulator, receiver
EYA81_RS14430	COG2205	protein histidine kinase activity
EYA81_RS14485	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EYA81_RS14490	COG0346	lactoylglutathione lyase activity
EYA81_RS14495	COG0564	pseudouridine synthase activity
EYA81_RS14500	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EYA81_RS14505	COG0542	response to heat
EYA81_RS14510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYA81_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
EYA81_RS14555	COG1253	flavin adenine dinucleotide binding
EYA81_RS14580	COG0482	sulfurtransferase activity
EYA81_RS14595	COG1757	Na H antiporter
EYA81_RS14600	COG2814	Major facilitator Superfamily
EYA81_RS14640	COG4974	Belongs to the 'phage' integrase family
EYA81_RS14655	COG0813	purine-nucleoside phosphorylase activity
EYA81_RS14660	COG4864	UPF0365 protein
EYA81_RS14675	COG0037	tRNA processing
EYA81_RS14685	COG1477	protein flavinylation
EYA81_RS14690	COG1971	Probably functions as a manganese efflux pump
EYA81_RS14705	COG0463	Glycosyl transferase, family 2
EYA81_RS14730	COG1629	transport
EYA81_RS14760	COG0148	phosphopyruvate hydratase activity
EYA81_RS14770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYA81_RS14780	COG1082	Xylose isomerase domain protein TIM barrel
EYA81_RS14795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYA81_RS14800	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYA81_RS14805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYA81_RS14815	COG0254	rRNA binding
EYA81_RS14825	COG0191	fructose-bisphosphate aldolase activity
EYA81_RS14830	COG0366	Alpha amylase catalytic
EYA81_RS14840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EYA81_RS14845	COG0511	ligase activity, forming carbon-carbon bonds
EYA81_RS14855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYA81_RS14870	COG2204	response regulator
EYA81_RS14875	COG4191	Histidine kinase
EYA81_RS14910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYA81_RS14920	COG1979	alcohol dehydrogenase
EYA81_RS14925	COG1530	ribonuclease E activity
EYA81_RS14930	COG0776	regulation of translation
EYA81_RS14935	COG1194	a g-specific adenine glycosylase
EYA81_RS14940	COG0629	single-stranded DNA binding
EYA81_RS14955	COG3033	Beta-eliminating lyase
EYA81_RS14960	COG5002	protein histidine kinase activity
EYA81_RS14965	COG0745	RESPONSE REGULATOR receiver
EYA81_RS14975	COG4771	TonB-dependent receptor
EYA81_RS14990	COG0488	(ABC) transporter
EYA81_RS15010	COG3591	Belongs to the peptidase S1B family
EYA81_RS15015	COG3591	Belongs to the peptidase S1B family
EYA81_RS15020	COG0641	radical SAM
EYA81_RS15035	COG1408	metallophosphoesterase
EYA81_RS15050	COG1410	methionine synthase
EYA81_RS15050	COG0646	methionine synthase
EYA81_RS15055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYA81_RS15060	COG0463	Glycosyl transferase, family 2
EYA81_RS15065	COG1940	carbohydrate kinase activity
EYA81_RS15080	COG2814	Major facilitator Superfamily
EYA81_RS15085	COG2942	2-epimerase
EYA81_RS15090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYA81_RS15125	COG4771	TonB-dependent receptor
EYA81_RS15130	COG0702	epimerase
EYA81_RS15140	COG3345	alpha-galactosidase
EYA81_RS15155	COG3345	alpha-galactosidase
EYA81_RS15165	COG1082	Xylose isomerase domain protein TIM barrel
EYA81_RS15205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYA81_RS15215	COG1032	radical SAM domain protein
EYA81_RS15235	COG3250	beta-galactosidase activity
EYA81_RS15240	COG0363	glucosamine-6-phosphate deaminase activity
EYA81_RS15250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYA81_RS15300	COG2264	protein methyltransferase activity
EYA81_RS15340	COG1592	Rubrerythrin
EYA81_RS15340	COG1773	rubredoxin
EYA81_RS15350	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYA81_RS15350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYA81_RS15355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EYA81_RS15395	COG0698	ribose 5-phosphate isomerase
EYA81_RS15410	COG1070	Carbohydrate kinase
EYA81_RS15415	COG2160	L-arabinose isomerase activity
EYA81_RS15440	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EYA81_RS15455	COG1482	cell wall glycoprotein biosynthetic process
EYA81_RS15475	COG0513	Belongs to the DEAD box helicase family
EYA81_RS15490	COG1218	3'(2'),5'-bisphosphate nucleotidase
EYA81_RS15495	COG3273	potassium ion transport
EYA81_RS15495	COG0471	metal ion transport
EYA81_RS15500	COG0529	Catalyzes the synthesis of activated sulfate
EYA81_RS15505	COG0175	sulfate reduction
EYA81_RS15510	COG2895	sulfate adenylyltransferase (ATP) activity
EYA81_RS15550	COG4974	Belongs to the 'phage' integrase family
EYA81_RS15580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYA81_RS15585	COG0242	peptide deformylase activity
EYA81_RS15595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYA81_RS15600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYA81_RS15605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYA81_RS15610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYA81_RS15615	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EYA81_RS15620	COG0674	pyruvate-flavodoxin oxidoreductase activity
EYA81_RS15620	COG1013	pyruvate-flavodoxin oxidoreductase activity
EYA81_RS15620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EYA81_RS15620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EYA81_RS15630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYA81_RS15635	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS15675	COG0484	heat shock protein binding
EYA81_RS15680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYA81_RS15685	COG0488	(ABC) transporter
EYA81_RS15700	COG2183	response to ionizing radiation
EYA81_RS15705	COG2202	Pas domain
EYA81_RS15705	COG2205	protein histidine kinase activity
EYA81_RS15720	COG4771	TonB-dependent receptor
EYA81_RS15725	COG4977	sequence-specific DNA binding
EYA81_RS15725	COG1917	Cupin 2, conserved barrel domain protein
EYA81_RS15750	COG0534	Mate efflux family protein
EYA81_RS15780	COG0306	phosphate transporter
EYA81_RS15790	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
EYA81_RS15800	COG0318	PFAM AMP-dependent synthetase and ligase
EYA81_RS15810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYA81_RS15820	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EYA81_RS15825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EYA81_RS15830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYA81_RS15835	COG0363	glucosamine-6-phosphate deaminase activity
EYA81_RS15845	COG0259	pyridoxamine-phosphate oxidase activity
EYA81_RS15890	COG1475	DNA binding
EYA81_RS15895	COG1475	DNA binding
EYA81_RS15945	COG0740	serine-type endopeptidase activity
EYA81_RS16055	COG3969	phosphoadenosine phosphosulfate
EYA81_RS16070	COG0322	excinuclease ABC activity
EYA81_RS16110	COG3279	Response regulator of the LytR AlgR family
EYA81_RS16120	COG0577	efflux transmembrane transporter activity
EYA81_RS16120	COG1136	(ABC) transporter
EYA81_RS16125	COG1136	(ABC) transporter
EYA81_RS16155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYA81_RS16165	COG0534	Mate efflux family protein
EYA81_RS16175	COG1177	transmembrane transport
EYA81_RS16180	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYA81_RS16185	COG3842	ATPase activity
EYA81_RS16210	COG4221	oxidoreductase activity
EYA81_RS16225	COG0488	(ABC) transporter
EYA81_RS16245	COG0513	Belongs to the DEAD box helicase family
EYA81_RS16250	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYA81_RS16255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYA81_RS16285	COG0545	Peptidyl-prolyl cis-trans isomerase
EYA81_RS16295	COG0534	Mate efflux family protein
EYA81_RS16300	COG1929	Belongs to the glycerate kinase type-1 family
EYA81_RS16310	COG1739	Uncharacterized protein family UPF0029
EYA81_RS16320	COG0778	Nitroreductase
EYA81_RS16330	COG1725	Transcriptional regulator
EYA81_RS16340	COG1131	(ABC) transporter
EYA81_RS16350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYA81_RS16350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYA81_RS16355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYA81_RS16360	COG0357	Ribosomal RNA small subunit methyltransferase G
EYA81_RS16385	COG2217	Heavy metal translocating P-type atpase
EYA81_RS16395	COG0321	lipoyl(octanoyl) transferase activity
EYA81_RS16465	COG0297	glycogen (starch) synthase activity
EYA81_RS16470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYA81_RS16480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYA81_RS16485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYA81_RS16500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYA81_RS16500	COG0072	phenylalanine-tRNA ligase activity
EYA81_RS16505	COG0217	transcriptional regulatory protein
EYA81_RS16515	COG1914	H( )-stimulated, divalent metal cation uptake system
EYA81_RS16520	COG0708	Exodeoxyribonuclease III
EYA81_RS16535	COG0481	GTPase activity
EYA81_RS16540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EYA81_RS16545	COG2205	protein histidine kinase activity
EYA81_RS16545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYA81_RS16560	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYA81_RS16565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYA81_RS16585	COG0612	Peptidase, M16
EYA81_RS16600	COG2205	protein histidine kinase activity
EYA81_RS16600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYA81_RS16600	COG0784	Response regulator, receiver
EYA81_RS16600	COG2198	Histidine kinase
EYA81_RS16605	COG0463	Glycosyl transferase, family 2
EYA81_RS16620	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EYA81_RS16625	COG1805	sodium ion transport
EYA81_RS16630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EYA81_RS16640	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EYA81_RS16650	COG2233	PERMEase
EYA81_RS16655	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYA81_RS16665	COG0024	Methionine aminopeptidase
EYA81_RS16675	COG0420	3'-5' exonuclease activity
EYA81_RS16705	COG2814	Major facilitator Superfamily
EYA81_RS16720	COG0564	pseudouridine synthase activity
EYA81_RS16725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYA81_RS16730	COG0574	Belongs to the PEP-utilizing enzyme family
EYA81_RS16730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYA81_RS16860	COG5002	protein histidine kinase activity
EYA81_RS16860	COG2205	protein histidine kinase activity
EYA81_RS16860	COG0784	Response regulator, receiver
EYA81_RS16930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYA81_RS16945	COG1678	Uncharacterized ACR, COG1678
EYA81_RS16950	COG4771	TonB-dependent receptor
EYA81_RS16980	COG0110	maltose O-acetyltransferase activity
EYA81_RS16990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYA81_RS17005	COG0738	Major facilitator superfamily
EYA81_RS17015	COG2059	Chromate
EYA81_RS17025	COG3969	phosphoadenosine phosphosulfate
EYA81_RS17030	COG1475	DNA binding
EYA81_RS17035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYA81_RS17050	COG1074	ATP-dependent DNA helicase activity
EYA81_RS17060	COG0556	nucleotide-excision repair
EYA81_RS17070	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EYA81_RS17100	COG1388	LysM domain
EYA81_RS17100	COG3942	CHAP domain
EYA81_RS17110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYA81_RS17115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYA81_RS17120	COG3104	oligopeptide transport
EYA81_RS17135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYA81_RS17145	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYA81_RS17150	COG1695	Transcriptional regulator
EYA81_RS17170	COG1086	Polysaccharide biosynthesis protein
EYA81_RS17175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYA81_RS17180	COG1083	cytidylyl-transferase
EYA81_RS17200	COG1028	Short-chain dehydrogenase reductase Sdr
EYA81_RS17220	COG2089	acid synthase
EYA81_RS17365	COG0740	serine-type endopeptidase activity
EYA81_RS17480	COG3969	phosphoadenosine phosphosulfate
EYA81_RS17495	COG3392	D12 class N6 adenine-specific DNA methyltransferase
EYA81_RS17505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYA81_RS17550	COG2244	polysaccharide biosynthetic process
EYA81_RS17555	COG0246	Mannitol dehydrogenase
EYA81_RS17565	COG1442	glycosyl transferase family 8
EYA81_RS17565	COG1216	Glycosyl transferase, family 2
EYA81_RS17570	COG1216	Glycosyl transferase, family 2
EYA81_RS17575	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS17590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYA81_RS17595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYA81_RS17610	COG3250	beta-galactosidase activity
EYA81_RS17615	COG2755	lipolytic protein G-D-S-L family
EYA81_RS17615	COG0657	acetylesterase activity
EYA81_RS17640	COG3059	membrane
EYA81_RS17645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYA81_RS17660	COG1120	ATPase activity
EYA81_RS17665	COG0534	Mate efflux family protein
EYA81_RS17670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EYA81_RS17680	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EYA81_RS17710	COG4771	TonB-dependent receptor
EYA81_RS17755	COG0439	Biotin carboxylase
EYA81_RS17765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYA81_RS17775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYA81_RS17785	COG1797	cobyrinic acid a,c-diamide synthase activity
EYA81_RS17790	COG2096	Adenosyltransferase
EYA81_RS17795	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYA81_RS17815	COG1492	cobalamin metabolic process
EYA81_RS17825	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EYA81_RS17830	COG2202	Pas domain
EYA81_RS17830	COG2205	protein histidine kinase activity
EYA81_RS17835	COG2202	Pas domain
EYA81_RS17835	COG2205	protein histidine kinase activity
EYA81_RS17850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYA81_RS17865	COG0442	prolyl-tRNA aminoacylation
EYA81_RS17935	COG1216	Glycosyl transferase, family 2
EYA81_RS17945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYA81_RS17950	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EYA81_RS17955	COG0438	transferase activity, transferring glycosyl groups
EYA81_RS17970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYA81_RS17975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYA81_RS17985	COG1506	peptidase
EYA81_RS17985	COG0823	Involved in the tonB-independent uptake of proteins
EYA81_RS18000	COG0504	CTP synthase activity
EYA81_RS18025	COG4656	Part of a membrane complex involved in electron transport
EYA81_RS18030	COG4658	electron transport chain
EYA81_RS18035	COG4659	FMN binding
EYA81_RS18040	COG4660	Part of a membrane complex involved in electron transport
EYA81_RS18045	COG4657	Part of a membrane complex involved in electron transport
EYA81_RS18050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYA81_RS18070	COG0356	it plays a direct role in the translocation of protons across the membrane
EYA81_RS18075	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYA81_RS18080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYA81_RS18085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYA81_RS18090	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYA81_RS18095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYA81_RS18100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYA81_RS18135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYA81_RS18145	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EYA81_RS18150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYA81_RS18165	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EYA81_RS18170	COG0540	Belongs to the ATCase OTCase family
EYA81_RS18175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYA81_RS18185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EYA81_RS18200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYA81_RS18205	COG2205	protein histidine kinase activity
EYA81_RS18310	COG0085	RNA polymerase activity
EYA81_RS18330	COG1061	Type III restriction enzyme res subunit
EYA81_RS18635	COG3969	phosphoadenosine phosphosulfate
EYA81_RS18730	COG3328	transposase activity
EYA81_RS18740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYA81_RS18785	COG0351	phosphomethylpyrimidine kinase
EYA81_RS18790	COG0352	thiamine-phosphate diphosphorylase activity
EYA81_RS18805	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYA81_RS18810	COG2022	thiamine diphosphate biosynthetic process
EYA81_RS18815	COG0352	thiamine-phosphate diphosphorylase activity
EYA81_RS18825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYA81_RS18840	COG2115	Belongs to the xylose isomerase family
EYA81_RS18845	COG0477	Major facilitator Superfamily
EYA81_RS18845	COG2814	Major facilitator Superfamily
EYA81_RS18850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYA81_RS18850	COG3153	acetyltransferase
EYA81_RS18860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYA81_RS18870	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYA81_RS18885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYA81_RS18915	COG2194	sulfuric ester hydrolase activity
EYA81_RS18935	COG3387	PFAM Glycoside hydrolase 15-related
EYA81_RS18945	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYA81_RS18955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYA81_RS18970	COG1904	glucuronate isomerase
EYA81_RS18975	COG1609	Transcriptional regulator
EYA81_RS18980	COG0246	Mannitol dehydrogenase
EYA81_RS19015	COG0513	Belongs to the DEAD box helicase family
EYA81_RS19020	COG3830	Belongs to the UPF0237 family
EYA81_RS19020	COG0560	Phosphoserine phosphatase
EYA81_RS19040	COG0343	queuine tRNA-ribosyltransferase activity
EYA81_RS19045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYA81_RS19050	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)