locus-tag	class	description
ITJ87_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ITJ87_RS00010	COG0778	Nitroreductase
ITJ87_RS00020	COG1640	4-alpha-glucanotransferase
ITJ87_RS00055	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS00060	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS00130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ITJ87_RS00170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ITJ87_RS00175	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS00185	COG0724	RNA recognition motif
ITJ87_RS00200	COG0359	binds to the 23S rRNA
ITJ87_RS00205	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ITJ87_RS00210	COG0360	Binds together with S18 to 16S ribosomal RNA
ITJ87_RS00235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ITJ87_RS00250	COG0519	Catalyzes the synthesis of GMP from XMP
ITJ87_RS00255	COG3250	beta-galactosidase activity
ITJ87_RS00295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ITJ87_RS00325	COG3279	Response regulator of the LytR AlgR family
ITJ87_RS00330	COG3275	phosphorelay sensor kinase activity
ITJ87_RS00340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ITJ87_RS00345	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ITJ87_RS00350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITJ87_RS00360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ITJ87_RS00370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ITJ87_RS00375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ITJ87_RS00385	COG0009	L-threonylcarbamoyladenylate synthase
ITJ87_RS00395	COG2207	Transcriptional regulator
ITJ87_RS00395	COG1609	Transcriptional regulator
ITJ87_RS00400	COG2133	pyrroloquinoline quinone binding
ITJ87_RS00400	COG5183	chlorophyll binding
ITJ87_RS00405	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ITJ87_RS00420	COG1785	Belongs to the alkaline phosphatase family
ITJ87_RS00430	COG3537	Alpha-1,2-mannosidase
ITJ87_RS00440	COG4206	TonB-dependent receptor
ITJ87_RS00440	COG1629	transport
ITJ87_RS00450	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS00455	COG3022	response to hydroperoxide
ITJ87_RS00460	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ITJ87_RS00460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ITJ87_RS00465	COG0514	ATP-dependent DNA helicase (RecQ)
ITJ87_RS00485	COG0436	Aminotransferase
ITJ87_RS00490	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ITJ87_RS00500	COG0358	DNA primase activity
ITJ87_RS00505	COG0302	gtp cyclohydrolase
ITJ87_RS00515	COG0149	triose-phosphate isomerase activity
ITJ87_RS00530	COG0739	heme binding
ITJ87_RS00535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ITJ87_RS00540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ITJ87_RS00560	COG0811	peptide transport
ITJ87_RS00570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ITJ87_RS00580	COG0039	L-malate dehydrogenase activity
ITJ87_RS00615	COG3118	belongs to the thioredoxin family
ITJ87_RS00620	COG0673	inositol 2-dehydrogenase activity
ITJ87_RS00630	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ITJ87_RS00635	COG0489	protein tyrosine kinase activity
ITJ87_RS00640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ITJ87_RS00645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ITJ87_RS00655	COG1570	exodeoxyribonuclease VII activity
ITJ87_RS00665	COG0482	sulfurtransferase activity
ITJ87_RS00685	COG3507	Belongs to the glycosyl hydrolase 43 family
ITJ87_RS00710	COG0702	epimerase
ITJ87_RS00715	COG1629	transport
ITJ87_RS00750	COG0673	inositol 2-dehydrogenase activity
ITJ87_RS00755	COG1408	metallophosphoesterase
ITJ87_RS00760	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ITJ87_RS00765	COG0179	Fumarylacetoacetate (FAA) hydrolase
ITJ87_RS00770	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ITJ87_RS00780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ITJ87_RS00785	COG0052	Belongs to the universal ribosomal protein uS2 family
ITJ87_RS00790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ITJ87_RS00795	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ITJ87_RS00805	COG0017	Asparaginyl-tRNA synthetase
ITJ87_RS00810	COG1187	pseudouridine synthase activity
ITJ87_RS00830	COG0110	maltose O-acetyltransferase activity
ITJ87_RS00835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ITJ87_RS00855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ITJ87_RS00870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITJ87_RS00880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ITJ87_RS00885	COG0516	GMP reductase activity
ITJ87_RS00885	COG0517	IMP dehydrogenase activity
ITJ87_RS00890	COG0514	ATP-dependent DNA helicase (RecQ)
ITJ87_RS00895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ITJ87_RS00900	COG0740	serine-type endopeptidase activity
ITJ87_RS00905	COG0544	peptidyl-prolyl cis-trans isomerase activity
ITJ87_RS00910	COG0724	RNA recognition motif
ITJ87_RS00920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ITJ87_RS00925	COG1127	ABC transporter
ITJ87_RS00930	COG1160	GTP binding
ITJ87_RS00935	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ITJ87_RS00940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS00990	COG4771	TonB-dependent receptor
ITJ87_RS00995	COG0702	epimerase
ITJ87_RS01020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ITJ87_RS01025	COG2202	Pas domain
ITJ87_RS01025	COG2205	protein histidine kinase activity
ITJ87_RS01030	COG2205	protein histidine kinase activity
ITJ87_RS01030	COG2202	Pas domain
ITJ87_RS01040	COG0436	Aminotransferase
ITJ87_RS01045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ITJ87_RS01095	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS01100	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS01105	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS01165	COG1629	transport
ITJ87_RS01175	COG1192	Involved in chromosome partitioning
ITJ87_RS01200	COG1120	ATPase activity
ITJ87_RS01205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ITJ87_RS01265	COG0456	acetyltransferase
ITJ87_RS01300	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS01305	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS01345	COG4753	response regulator
ITJ87_RS01345	COG2207	Transcriptional regulator
ITJ87_RS01350	COG5002	protein histidine kinase activity
ITJ87_RS01355	COG2205	protein histidine kinase activity
ITJ87_RS01365	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ITJ87_RS01370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ITJ87_RS01375	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ITJ87_RS01385	COG2204	response regulator
ITJ87_RS01390	COG0460	homoserine dehydrogenase
ITJ87_RS01390	COG0527	aspartate kinase activity
ITJ87_RS01400	COG2942	2-epimerase
ITJ87_RS01405	COG2211	Major facilitator Superfamily
ITJ87_RS01410	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ITJ87_RS01415	COG4124	Belongs to the glycosyl hydrolase 26 family
ITJ87_RS01475	COG1629	transport
ITJ87_RS01475	COG4206	TonB-dependent receptor
ITJ87_RS01480	COG4124	Belongs to the glycosyl hydrolase 26 family
ITJ87_RS01495	COG0561	phosphatase activity
ITJ87_RS01500	COG4771	TonB-dependent receptor
ITJ87_RS01505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ITJ87_RS01515	COG3458	cephalosporin-C deacetylase activity
ITJ87_RS01520	COG0662	Cupin 2, conserved barrel domain protein
ITJ87_RS01520	COG2207	Transcriptional regulator
ITJ87_RS01525	COG3250	beta-galactosidase activity
ITJ87_RS01530	COG3459	Glycosyltransferase 36 associated
ITJ87_RS01535	COG0667	Aldo Keto reductase
ITJ87_RS01540	COG4948	Mandelate Racemase Muconate Lactonizing
ITJ87_RS01555	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS01560	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS01565	COG0737	Belongs to the 5'-nucleotidase family
ITJ87_RS01570	COG0737	Belongs to the 5'-nucleotidase family
ITJ87_RS01575	COG0335	large ribosomal subunit rRNA binding
ITJ87_RS01580	COG1940	carbohydrate kinase activity
ITJ87_RS01585	COG1136	(ABC) transporter
ITJ87_RS01590	COG0577	efflux transmembrane transporter activity
ITJ87_RS01590	COG1136	(ABC) transporter
ITJ87_RS01595	COG1136	(ABC) transporter
ITJ87_RS01595	COG0577	efflux transmembrane transporter activity
ITJ87_RS01600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS01620	COG2996	Protein conserved in bacteria
ITJ87_RS01625	COG0039	L-malate dehydrogenase activity
ITJ87_RS01650	COG0137	argininosuccinate synthase activity
ITJ87_RS01660	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ITJ87_RS01665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ITJ87_RS01670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ITJ87_RS01675	COG1917	Cupin 2, conserved barrel domain protein
ITJ87_RS01675	COG1396	sequence-specific DNA binding
ITJ87_RS01680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ITJ87_RS01710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ITJ87_RS01720	COG2890	protein-(glutamine-N5) methyltransferase activity
ITJ87_RS01725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITJ87_RS01725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ITJ87_RS01735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ITJ87_RS01755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ITJ87_RS01765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ITJ87_RS01770	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ITJ87_RS01800	COG0564	pseudouridine synthase activity
ITJ87_RS01810	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ITJ87_RS01815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ITJ87_RS01820	COG1216	Glycosyl transferase, family 2
ITJ87_RS01825	COG2003	Belongs to the UPF0758 family
ITJ87_RS01835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITJ87_RS01850	COG1785	Belongs to the alkaline phosphatase family
ITJ87_RS01855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ITJ87_RS01860	COG0280	phosphate acetyltransferase
ITJ87_RS01865	COG1380	Effector of murein hydrolase LrgA
ITJ87_RS01870	COG1346	cytolysis
ITJ87_RS01885	COG0312	modulator of DNA gyrase
ITJ87_RS01890	COG0312	modulator of DNA gyrase
ITJ87_RS01895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ITJ87_RS01900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ITJ87_RS01905	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ITJ87_RS01915	COG0733	neurotransmitter:sodium symporter activity
ITJ87_RS01925	COG1136	(ABC) transporter
ITJ87_RS01930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ITJ87_RS01935	COG0475	glutathione-regulated potassium exporter activity
ITJ87_RS01935	COG0589	response to stress
ITJ87_RS01940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ITJ87_RS01945	COG0702	epimerase
ITJ87_RS01950	COG4206	TonB-dependent receptor
ITJ87_RS01950	COG1629	transport
ITJ87_RS01960	COG4206	TonB-dependent receptor
ITJ87_RS01960	COG1629	transport
ITJ87_RS01965	COG0702	epimerase
ITJ87_RS01995	COG3876	Protein conserved in bacteria
ITJ87_RS02000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ITJ87_RS02030	COG2807	transmembrane transport
ITJ87_RS02035	COG3876	Protein conserved in bacteria
ITJ87_RS02055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ITJ87_RS02060	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ITJ87_RS02070	COG0423	glycine-tRNA ligase activity
ITJ87_RS02075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ITJ87_RS02110	COG1629	transport
ITJ87_RS02110	COG4206	TonB-dependent receptor
ITJ87_RS02135	COG4771	TonB-dependent receptor
ITJ87_RS02140	COG0702	epimerase
ITJ87_RS02170	COG2954	triphosphatase activity
ITJ87_RS02175	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ITJ87_RS02205	COG1629	transport
ITJ87_RS02205	COG4206	TonB-dependent receptor
ITJ87_RS02210	COG1022	Amp-dependent synthetase and ligase
ITJ87_RS02215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ITJ87_RS02220	COG4942	peptidase
ITJ87_RS02235	COG0756	dUTP diphosphatase activity
ITJ87_RS02275	COG2001	Belongs to the MraZ family
ITJ87_RS02290	COG0768	penicillin binding
ITJ87_RS02295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ITJ87_RS02300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITJ87_RS02305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ITJ87_RS02310	COG0772	Belongs to the SEDS family
ITJ87_RS02315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ITJ87_RS02320	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ITJ87_RS02330	COG0849	cell division
ITJ87_RS02335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ITJ87_RS02340	COG1610	YqeY-like protein
ITJ87_RS02345	COG1381	Involved in DNA repair and RecF pathway recombination
ITJ87_RS02355	COG0268	Binds directly to 16S ribosomal RNA
ITJ87_RS02360	COG0187	DNA topoisomerase II activity
ITJ87_RS02370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ITJ87_RS02380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ITJ87_RS02390	COG1629	transport
ITJ87_RS02390	COG4206	TonB-dependent receptor
ITJ87_RS02405	COG2431	L-lysine efflux transmembrane transporter activity
ITJ87_RS02415	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ITJ87_RS02415	COG3408	Glycogen debranching enzyme
ITJ87_RS02420	COG3426	butyrate kinase activity
ITJ87_RS02425	COG0280	phosphate acetyltransferase
ITJ87_RS02440	COG2166	iron-sulfur cluster assembly
ITJ87_RS02445	COG3655	Transcriptional regulator
ITJ87_RS02475	COG1266	CAAX protease self-immunity
ITJ87_RS02485	COG0196	riboflavin kinase activity
ITJ87_RS02490	COG1011	Hydrolase
ITJ87_RS02495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ITJ87_RS02500	COG0582	viral genome integration into host DNA
ITJ87_RS02555	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ITJ87_RS02595	COG1773	rubredoxin
ITJ87_RS02600	COG1283	sodium-dependent phosphate transmembrane transporter activity
ITJ87_RS02605	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ITJ87_RS02610	COG2205	protein histidine kinase activity
ITJ87_RS02615	COG0006	proline dipeptidase activity
ITJ87_RS02630	COG0509	glycine decarboxylation via glycine cleavage system
ITJ87_RS02635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ITJ87_RS02640	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ITJ87_RS02645	COG2066	Belongs to the glutaminase family
ITJ87_RS02670	COG3119	arylsulfatase activity
ITJ87_RS02695	COG0702	epimerase
ITJ87_RS02700	COG4771	TonB-dependent receptor
ITJ87_RS02720	COG0793	Belongs to the peptidase S41A family
ITJ87_RS02725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITJ87_RS02745	COG1040	competence protein
ITJ87_RS02760	COG2816	NAD+ diphosphatase activity
ITJ87_RS02780	COG0018	arginyl-trna synthetase
ITJ87_RS02800	COG0708	Exodeoxyribonuclease III
ITJ87_RS02805	COG0339	signal peptide processing
ITJ87_RS02810	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ITJ87_RS02820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ITJ87_RS02820	COG0674	pyruvate-flavodoxin oxidoreductase activity
ITJ87_RS02825	COG1013	pyruvate-flavodoxin oxidoreductase activity
ITJ87_RS02830	COG1629	transport
ITJ87_RS02830	COG4206	TonB-dependent receptor
ITJ87_RS02860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ITJ87_RS02865	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ITJ87_RS02875	COG1217	gtp-binding protein TYPA
ITJ87_RS02880	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ITJ87_RS02905	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS02910	COG1854	S-ribosylhomocysteine lyase activity
ITJ87_RS02915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ITJ87_RS02925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ITJ87_RS02930	COG4591	ABC-type transport system involved in lipoprotein release permease component
ITJ87_RS02945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ITJ87_RS02950	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS02965	COG0606	chelatase, subunit chli
ITJ87_RS02975	COG3594	Acyltransferase
ITJ87_RS02980	COG2972	Histidine kinase
ITJ87_RS02985	COG3279	Response regulator of the LytR AlgR family
ITJ87_RS03005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ87_RS03005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ87_RS03020	COG3475	LICD family
ITJ87_RS03030	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS03040	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ITJ87_RS03045	COG0545	Peptidyl-prolyl cis-trans isomerase
ITJ87_RS03050	COG0545	Peptidyl-prolyl cis-trans isomerase
ITJ87_RS03055	COG1522	sequence-specific DNA binding
ITJ87_RS03095	COG2003	Belongs to the UPF0758 family
ITJ87_RS03150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITJ87_RS03155	COG3250	beta-galactosidase activity
ITJ87_RS03165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ITJ87_RS03185	COG2755	lipolytic protein G-D-S-L family
ITJ87_RS03185	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ITJ87_RS03205	COG0702	epimerase
ITJ87_RS03210	COG4206	TonB-dependent receptor
ITJ87_RS03210	COG1629	transport
ITJ87_RS03225	COG2814	Major facilitator Superfamily
ITJ87_RS03240	COG1940	carbohydrate kinase activity
ITJ87_RS03250	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ITJ87_RS03290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ITJ87_RS03295	COG3409	Peptidoglycan-binding domain 1 protein
ITJ87_RS03295	COG0793	Belongs to the peptidase S41A family
ITJ87_RS03300	COG0671	phosphoesterase, PA-phosphatase related
ITJ87_RS03315	COG1053	succinate dehydrogenase
ITJ87_RS03320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ITJ87_RS03360	COG0826	peptidase U32
ITJ87_RS03365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITJ87_RS03385	COG0557	exoribonuclease II activity
ITJ87_RS03400	COG1045	serine acetyltransferase
ITJ87_RS03405	COG0116	Belongs to the methyltransferase superfamily
ITJ87_RS03405	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ITJ87_RS03410	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS03410	COG1506	peptidase
ITJ87_RS03415	COG0151	Belongs to the GarS family
ITJ87_RS03425	COG1238	metal cluster binding
ITJ87_RS03455	COG2942	2-epimerase
ITJ87_RS03465	COG4206	TonB-dependent receptor
ITJ87_RS03465	COG1629	transport
ITJ87_RS03470	COG1501	Belongs to the glycosyl hydrolase 31 family
ITJ87_RS03475	COG2205	protein histidine kinase activity
ITJ87_RS03475	COG3292	Two component regulator propeller
ITJ87_RS03475	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS03480	COG3291	Pkd domain containing protein
ITJ87_RS03530	COG4585	Histidine kinase
ITJ87_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS03550	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ITJ87_RS03580	COG3023	N-Acetylmuramoyl-L-alanine amidase
ITJ87_RS03610	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS03620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ITJ87_RS03625	COG0084	hydrolase, TatD family'
ITJ87_RS03630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ITJ87_RS03635	COG0594	ribonuclease P activity
ITJ87_RS03650	COG1611	Belongs to the LOG family
ITJ87_RS03660	COG2205	protein histidine kinase activity
ITJ87_RS03770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ITJ87_RS03775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ITJ87_RS03775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ITJ87_RS03780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ITJ87_RS03785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ITJ87_RS03790	COG1968	undecaprenyl-diphosphatase activity
ITJ87_RS03800	COG2177	Part of the ABC transporter FtsEX involved in
ITJ87_RS03805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ITJ87_RS03815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ITJ87_RS03825	COG0427	acetyl-CoA hydrolase
ITJ87_RS03895	COG3279	Response regulator of the LytR AlgR family
ITJ87_RS03910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ITJ87_RS03915	COG1592	Rubrerythrin
ITJ87_RS03920	COG0659	secondary active sulfate transmembrane transporter activity
ITJ87_RS03935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ITJ87_RS03935	COG0731	radical SAM domain protein
ITJ87_RS03945	COG1476	TRANSCRIPTIONal
ITJ87_RS03965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITJ87_RS03970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITJ87_RS03975	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ITJ87_RS03980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ITJ87_RS03985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITJ87_RS03990	COG0495	leucyl-tRNA aminoacylation
ITJ87_RS04000	COG0582	viral genome integration into host DNA
ITJ87_RS04060	COG1595	DNA-templated transcription, initiation
ITJ87_RS04070	COG0697	spore germination
ITJ87_RS04080	COG4948	Mandelate Racemase Muconate Lactonizing
ITJ87_RS04090	COG1629	transport
ITJ87_RS04090	COG4206	TonB-dependent receptor
ITJ87_RS04105	COG0738	Major facilitator superfamily
ITJ87_RS04120	COG1609	Transcriptional regulator
ITJ87_RS04140	COG4771	TonB-dependent receptor
ITJ87_RS04170	COG4948	Mandelate Racemase Muconate Lactonizing
ITJ87_RS04185	COG1629	transport
ITJ87_RS04225	COG5002	protein histidine kinase activity
ITJ87_RS04235	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04275	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ITJ87_RS04285	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04285	COG2205	protein histidine kinase activity
ITJ87_RS04285	COG3292	Two component regulator propeller
ITJ87_RS04290	COG4948	Mandelate Racemase Muconate Lactonizing
ITJ87_RS04315	COG1629	transport
ITJ87_RS04315	COG4206	TonB-dependent receptor
ITJ87_RS04320	COG0702	epimerase
ITJ87_RS04340	COG3408	Glycogen debranching enzyme
ITJ87_RS04345	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS04350	COG1501	Belongs to the glycosyl hydrolase 31 family
ITJ87_RS04365	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ITJ87_RS04380	COG0012	GTP binding
ITJ87_RS04400	COG1629	transport
ITJ87_RS04415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITJ87_RS04415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ITJ87_RS04420	COG0142	geranyltranstransferase activity
ITJ87_RS04425	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ITJ87_RS04430	COG1694	Mazg nucleotide pyrophosphohydrolase
ITJ87_RS04435	COG1490	D-aminoacyl-tRNA deacylase activity
ITJ87_RS04440	COG0322	excinuclease ABC activity
ITJ87_RS04445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ITJ87_RS04465	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04465	COG2205	protein histidine kinase activity
ITJ87_RS04465	COG3292	Two component regulator propeller
ITJ87_RS04465	COG2205	protein histidine kinase activity
ITJ87_RS04465	COG3292	Two component regulator propeller
ITJ87_RS04465	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04470	COG4206	TonB-dependent receptor
ITJ87_RS04470	COG1629	transport
ITJ87_RS04505	COG3408	Glycogen debranching enzyme
ITJ87_RS04515	COG2017	converts alpha-aldose to the beta-anomer
ITJ87_RS04525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ITJ87_RS04530	COG2715	membrane protein required for spore maturation
ITJ87_RS04535	COG2234	aminopeptidase activity
ITJ87_RS04545	COG2255	four-way junction helicase activity
ITJ87_RS04560	COG3591	Belongs to the peptidase S1B family
ITJ87_RS04565	COG3634	alkyl hydroperoxide reductase activity
ITJ87_RS04575	COG0583	DNA-binding transcription factor activity
ITJ87_RS04580	COG0783	Belongs to the Dps family
ITJ87_RS04595	COG4176	ABC-type proline glycine betaine transport system permease component
ITJ87_RS04600	COG2113	Glycine betaine
ITJ87_RS04645	COG0513	Belongs to the DEAD box helicase family
ITJ87_RS04655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ITJ87_RS04660	COG0517	IMP dehydrogenase activity
ITJ87_RS04660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ITJ87_RS04665	COG0612	Peptidase, M16
ITJ87_RS04670	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ITJ87_RS04685	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ITJ87_RS04690	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS04695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ITJ87_RS04700	COG1312	Catalyzes the dehydration of D-mannonate
ITJ87_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS04715	COG0681	Belongs to the peptidase S26 family
ITJ87_RS04720	COG0681	Belongs to the peptidase S26 family
ITJ87_RS04725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ITJ87_RS04745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ITJ87_RS04750	COG5492	domain, Protein
ITJ87_RS04760	COG0702	epimerase
ITJ87_RS04765	COG4771	TonB-dependent receptor
ITJ87_RS04770	COG3119	arylsulfatase activity
ITJ87_RS04775	COG3292	Two component regulator propeller
ITJ87_RS04775	COG2205	protein histidine kinase activity
ITJ87_RS04775	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04775	COG3292	Two component regulator propeller
ITJ87_RS04775	COG2205	protein histidine kinase activity
ITJ87_RS04775	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS04790	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITJ87_RS04805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS04825	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ITJ87_RS04830	COG3119	arylsulfatase activity
ITJ87_RS04845	COG0482	sulfurtransferase activity
ITJ87_RS04855	COG0205	6-phosphofructokinase activity
ITJ87_RS04860	COG0571	ribonuclease III activity
ITJ87_RS04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ITJ87_RS04870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ITJ87_RS04875	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ITJ87_RS04880	COG3083	sulfuric ester hydrolase activity
ITJ87_RS04885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ITJ87_RS04895	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS04900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ITJ87_RS04905	COG4750	Nucleotidyl transferase
ITJ87_RS04910	COG3475	LICD family
ITJ87_RS04925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ITJ87_RS04925	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ITJ87_RS04930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ITJ87_RS04935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ITJ87_RS04945	COG1368	sulfuric ester hydrolase activity
ITJ87_RS04955	COG1442	glycosyl transferase family 8
ITJ87_RS04955	COG1216	Glycosyl transferase, family 2
ITJ87_RS04960	COG3754	Rhamnan synthesis protein F
ITJ87_RS04980	COG1215	transferase activity, transferring glycosyl groups
ITJ87_RS04995	COG1132	(ABC) transporter
ITJ87_RS05000	COG1132	(ABC) transporter
ITJ87_RS05010	COG0673	inositol 2-dehydrogenase activity
ITJ87_RS05025	COG3341	Caulimovirus viroplasmin
ITJ87_RS05025	COG0328	RNA-DNA hybrid ribonuclease activity
ITJ87_RS05035	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ITJ87_RS05040	COG1166	arginine decarboxylase activity
ITJ87_RS05045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ITJ87_RS05050	COG1595	DNA-templated transcription, initiation
ITJ87_RS05075	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS05075	COG2205	protein histidine kinase activity
ITJ87_RS05075	COG3292	Two component regulator propeller
ITJ87_RS05080	COG2272	Belongs to the type-B carboxylesterase lipase family
ITJ87_RS05085	COG4771	TonB-dependent receptor
ITJ87_RS05115	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS05120	COG2382	esterase
ITJ87_RS05120	COG3507	Belongs to the glycosyl hydrolase 43 family
ITJ87_RS05120	COG3693	PFAM glycoside hydrolase, family 10
ITJ87_RS05125	COG2382	esterase
ITJ87_RS05130	COG2382	esterase
ITJ87_RS05135	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS05140	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS05145	COG0779	Required for maturation of 30S ribosomal subunits
ITJ87_RS05150	COG0195	Participates in both transcription termination and antitermination
ITJ87_RS05155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ITJ87_RS05165	COG0719	Fe-S assembly protein
ITJ87_RS05170	COG0396	ATPase activity
ITJ87_RS05175	COG0719	Fe-S assembly protein
ITJ87_RS05180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ITJ87_RS05185	COG0393	Putative heavy-metal-binding
ITJ87_RS05190	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ITJ87_RS05200	COG4206	TonB-dependent receptor
ITJ87_RS05200	COG1629	transport
ITJ87_RS05215	COG1185	polyribonucleotide nucleotidyltransferase activity
ITJ87_RS05225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ITJ87_RS05230	COG0537	adenosine 5'-monophosphoramidase activity
ITJ87_RS05235	COG0662	Cupin 2, conserved barrel domain protein
ITJ87_RS05235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ITJ87_RS05290	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05295	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05300	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05330	COG4771	TonB-dependent receptor
ITJ87_RS05350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ITJ87_RS05355	COG2205	protein histidine kinase activity
ITJ87_RS05355	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS05355	COG3292	Two component regulator propeller
ITJ87_RS05360	COG1501	Belongs to the glycosyl hydrolase 31 family
ITJ87_RS05365	COG3250	beta-galactosidase activity
ITJ87_RS05370	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS05390	COG2096	Adenosyltransferase
ITJ87_RS05400	COG0514	ATP-dependent DNA helicase (RecQ)
ITJ87_RS05475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ITJ87_RS05480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ITJ87_RS05520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ITJ87_RS05530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ITJ87_RS05535	COG0006	proline dipeptidase activity
ITJ87_RS05540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ITJ87_RS05545	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ITJ87_RS05595	COG0081	regulation of translation
ITJ87_RS05600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ITJ87_RS05605	COG0222	ribosome binding
ITJ87_RS05610	COG0085	RNA polymerase activity
ITJ87_RS05615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ITJ87_RS05625	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ITJ87_RS05630	COG0049	tRNA binding
ITJ87_RS05635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ITJ87_RS05640	COG0051	transcription antitermination factor activity, RNA binding
ITJ87_RS05645	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ITJ87_RS05650	COG0088	Forms part of the polypeptide exit tunnel
ITJ87_RS05655	COG0089	rRNA binding
ITJ87_RS05660	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ITJ87_RS05665	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ITJ87_RS05670	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ITJ87_RS05675	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ITJ87_RS05680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ITJ87_RS05685	COG0255	Belongs to the universal ribosomal protein uL29 family
ITJ87_RS05690	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ITJ87_RS05695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ITJ87_RS05700	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ITJ87_RS05705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ITJ87_RS05710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ITJ87_RS05715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ITJ87_RS05720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ITJ87_RS05725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ITJ87_RS05730	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ITJ87_RS05735	COG1841	ribosomal large subunit assembly
ITJ87_RS05740	COG0200	Binds to the 23S rRNA
ITJ87_RS05755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ITJ87_RS05760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ITJ87_RS05765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ITJ87_RS05770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ITJ87_RS05775	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ITJ87_RS05780	COG0202	RNA polymerase activity
ITJ87_RS05785	COG0203	ribosomal protein L17
ITJ87_RS05800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ITJ87_RS05815	COG2431	L-lysine efflux transmembrane transporter activity
ITJ87_RS05830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ITJ87_RS05840	COG1228	amidohydrolase
ITJ87_RS05850	COG2986	histidine ammonia-lyase
ITJ87_RS05855	COG1309	transcriptional regulator
ITJ87_RS05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS05875	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05880	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05885	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS05910	COG1696	Membrane protein involved in D-alanine export
ITJ87_RS05915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ITJ87_RS06000	COG1131	(ABC) transporter
ITJ87_RS06020	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ITJ87_RS06040	COG0564	pseudouridine synthase activity
ITJ87_RS06045	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS06045	COG1506	peptidase
ITJ87_RS06055	COG2204	response regulator
ITJ87_RS06060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ITJ87_RS06065	COG0612	Peptidase, M16
ITJ87_RS06070	COG0534	Mate efflux family protein
ITJ87_RS06075	COG0784	Response regulator, receiver
ITJ87_RS06075	COG2205	protein histidine kinase activity
ITJ87_RS06110	COG0784	Response regulator, receiver
ITJ87_RS06110	COG2205	protein histidine kinase activity
ITJ87_RS06115	COG0488	(ABC) transporter
ITJ87_RS06120	COG3590	peptidase
ITJ87_RS06125	COG0138	bifunctional purine biosynthesis protein purh
ITJ87_RS06135	COG1792	Involved in formation and maintenance of cell shape
ITJ87_RS06150	COG0772	Belongs to the SEDS family
ITJ87_RS06160	COG1774	PSP1 C-terminal conserved region
ITJ87_RS06165	COG0470	DNA polymerase III
ITJ87_RS06170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ITJ87_RS06185	COG0826	peptidase U32
ITJ87_RS06195	COG4771	TonB-dependent receptor
ITJ87_RS06205	COG3292	Two component regulator propeller
ITJ87_RS06205	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS06205	COG3292	Two component regulator propeller
ITJ87_RS06205	COG2205	protein histidine kinase activity
ITJ87_RS06205	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS06205	COG2205	protein histidine kinase activity
ITJ87_RS06210	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ITJ87_RS06215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ITJ87_RS06220	COG0288	reversible hydration of carbon dioxide
ITJ87_RS06225	COG0252	asparaginase activity
ITJ87_RS06230	COG0527	aspartate kinase activity
ITJ87_RS06230	COG0460	homoserine dehydrogenase
ITJ87_RS06235	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ITJ87_RS06240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ITJ87_RS06320	COG0628	permease
ITJ87_RS06325	COG1435	thymidine kinase activity
ITJ87_RS06335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ITJ87_RS06350	COG2095	MarC family integral membrane protein
ITJ87_RS06390	COG1629	transport
ITJ87_RS06395	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS06400	COG1629	transport
ITJ87_RS06400	COG4206	TonB-dependent receptor
ITJ87_RS06410	COG4206	TonB-dependent receptor
ITJ87_RS06410	COG1629	transport
ITJ87_RS06425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ITJ87_RS06435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ITJ87_RS06435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ITJ87_RS06440	COG0531	amino acid
ITJ87_RS06450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITJ87_RS06455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS06460	COG1162	GTPase activity
ITJ87_RS06465	COG0233	cytoplasmic translational termination
ITJ87_RS06470	COG0528	UMP kinase activity
ITJ87_RS06480	COG0697	spore germination
ITJ87_RS06485	COG2217	Heavy metal translocating P-type atpase
ITJ87_RS06490	COG0534	Mate efflux family protein
ITJ87_RS06545	COG0792	nuclease activity
ITJ87_RS06570	COG1183	phosphatidylcholine synthase activity
ITJ87_RS06575	COG0688	phosphatidylethanolamine metabolic process
ITJ87_RS06600	COG0802	atpase or kinase
ITJ87_RS06605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ITJ87_RS06615	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ITJ87_RS06625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ITJ87_RS06635	COG0490	domain, Protein
ITJ87_RS06635	COG2985	domain, Protein
ITJ87_RS06640	COG1506	peptidase
ITJ87_RS06640	COG4946	Tricorn protease homolog
ITJ87_RS06640	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS06665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ITJ87_RS06680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ITJ87_RS06685	COG0742	ribosomal rna small subunit methyltransferase
ITJ87_RS06715	COG0739	heme binding
ITJ87_RS06725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ITJ87_RS06730	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ87_RS06730	COG1388	LysM domain
ITJ87_RS06740	COG1475	DNA binding
ITJ87_RS06745	COG1192	Involved in chromosome partitioning
ITJ87_RS06760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ITJ87_RS06765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITJ87_RS06780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ITJ87_RS06795	COG0138	bifunctional purine biosynthesis protein purh
ITJ87_RS06800	COG1196	nuclear chromosome segregation
ITJ87_RS06805	COG2239	Acts as a magnesium transporter
ITJ87_RS06810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ITJ87_RS06820	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITJ87_RS06850	COG1119	ATPase activity
ITJ87_RS06860	COG0668	transmembrane transport
ITJ87_RS06875	COG4412	M6 family metalloprotease domain protein
ITJ87_RS06875	COG1404	Belongs to the peptidase S8 family
ITJ87_RS06880	COG5002	protein histidine kinase activity
ITJ87_RS06880	COG2205	protein histidine kinase activity
ITJ87_RS06880	COG0784	Response regulator, receiver
ITJ87_RS06890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ITJ87_RS06895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ITJ87_RS06900	COG0713	ATP synthesis coupled electron transport
ITJ87_RS06905	COG0839	Belongs to the complex I subunit 6 family
ITJ87_RS06910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ITJ87_RS06915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ITJ87_RS06920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ITJ87_RS06920	COG0649	NAD binding
ITJ87_RS06925	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ITJ87_RS06930	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ITJ87_RS06940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ITJ87_RS06945	COG0569	domain protein
ITJ87_RS06950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ITJ87_RS06965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ITJ87_RS06970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ITJ87_RS06975	COG0805	protein transport
ITJ87_RS06990	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ITJ87_RS06995	COG3775	system Galactitol-specific IIC component
ITJ87_RS07000	COG0546	phosphoglycolate phosphatase activity
ITJ87_RS07005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ITJ87_RS07010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ITJ87_RS07020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ITJ87_RS07025	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS07025	COG1506	peptidase
ITJ87_RS07030	COG4821	SIS domain
ITJ87_RS07035	COG2814	Major facilitator Superfamily
ITJ87_RS07045	COG1242	4 iron, 4 sulfur cluster binding
ITJ87_RS07055	COG0363	glucosamine-6-phosphate deaminase activity
ITJ87_RS07105	COG0681	Belongs to the peptidase S26 family
ITJ87_RS07115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS07175	COG0628	permease
ITJ87_RS07180	COG0009	L-threonylcarbamoyladenylate synthase
ITJ87_RS07185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ITJ87_RS07190	COG0561	phosphatase activity
ITJ87_RS07205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITJ87_RS07220	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS07230	COG1073	alpha beta
ITJ87_RS07250	COG3487	Iron-regulated protein
ITJ87_RS07275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ITJ87_RS07275	COG1333	cytochrome c biogenesis protein
ITJ87_RS07300	COG4206	TonB-dependent receptor
ITJ87_RS07300	COG1629	transport
ITJ87_RS07315	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ITJ87_RS07325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITJ87_RS07330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ITJ87_RS07330	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ITJ87_RS07335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ITJ87_RS07340	COG1078	dGTPase activity
ITJ87_RS07345	COG0284	orotidine-5'-phosphate decarboxylase activity
ITJ87_RS07350	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ITJ87_RS07355	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ITJ87_RS07360	COG1704	LemA family
ITJ87_RS07375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ITJ87_RS07380	COG2226	methyltransferase
ITJ87_RS07385	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ITJ87_RS07390	COG1702	phosphate starvation-inducible protein PhoH
ITJ87_RS07405	COG1496	oxidoreductase activity
ITJ87_RS07410	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ITJ87_RS07415	COG0563	adenylate kinase activity
ITJ87_RS07420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ITJ87_RS07430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ITJ87_RS07430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ITJ87_RS07445	COG0101	tRNA pseudouridine synthase activity
ITJ87_RS07455	COG1956	GAF domain-containing protein
ITJ87_RS07465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ITJ87_RS07475	COG2755	lipolytic protein G-D-S-L family
ITJ87_RS07475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ITJ87_RS07500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ITJ87_RS07525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ITJ87_RS07530	COG0793	Belongs to the peptidase S41A family
ITJ87_RS07535	COG2131	deaminase
ITJ87_RS07545	COG0339	signal peptide processing
ITJ87_RS07555	COG1970	mechanosensitive ion channel activity
ITJ87_RS07560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ITJ87_RS07560	COG0519	Catalyzes the synthesis of GMP from XMP
ITJ87_RS07565	COG0519	Catalyzes the synthesis of GMP from XMP
ITJ87_RS07590	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS07605	COG0297	glycogen (starch) synthase activity
ITJ87_RS07610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ITJ87_RS07615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ITJ87_RS07625	COG0543	2 iron, 2 sulfur cluster binding
ITJ87_RS07640	COG3279	Response regulator of the LytR AlgR family
ITJ87_RS07645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ITJ87_RS07650	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ITJ87_RS07655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ITJ87_RS07670	COG1191	sigma factor activity
ITJ87_RS07680	COG3537	Alpha-1,2-mannosidase
ITJ87_RS07685	COG4771	TonB-dependent receptor
ITJ87_RS07710	COG3537	Alpha-1,2-mannosidase
ITJ87_RS07725	COG4206	TonB-dependent receptor
ITJ87_RS07725	COG1629	transport
ITJ87_RS07745	COG3537	Alpha-1,2-mannosidase
ITJ87_RS07755	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
ITJ87_RS07760	COG3537	Alpha-1,2-mannosidase
ITJ87_RS07775	COG0791	NLP P60 protein
ITJ87_RS07790	COG0612	Peptidase, M16
ITJ87_RS07795	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ITJ87_RS07800	COG1597	lipid kinase activity
ITJ87_RS07805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ITJ87_RS07810	COG0534	Mate efflux family protein
ITJ87_RS07840	COG3340	Belongs to the peptidase S51 family
ITJ87_RS07845	COG2378	regulation of single-species biofilm formation
ITJ87_RS07915	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS07960	COG4983	Phage plasmid primase, P4 family domain protein
ITJ87_RS08065	COG0551	DNA topoisomerase type I activity
ITJ87_RS08065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ87_RS08110	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ITJ87_RS08130	COG1086	Polysaccharide biosynthesis protein
ITJ87_RS08145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ITJ87_RS08180	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ITJ87_RS08195	COG2205	protein histidine kinase activity
ITJ87_RS08195	COG0784	Response regulator, receiver
ITJ87_RS08230	COG1192	Involved in chromosome partitioning
ITJ87_RS08425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ITJ87_RS08430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ITJ87_RS08435	COG1663	tetraacyldisaccharide 4'-kinase activity
ITJ87_RS08440	COG0616	signal peptide processing
ITJ87_RS08480	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ITJ87_RS08485	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ITJ87_RS08490	COG0066	3-isopropylmalate dehydratase activity
ITJ87_RS08510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ITJ87_RS08520	COG0514	ATP-dependent DNA helicase (RecQ)
ITJ87_RS08540	COG0735	belongs to the Fur family
ITJ87_RS08545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ITJ87_RS08560	COG0124	histidyl-tRNA synthetase
ITJ87_RS08580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ITJ87_RS08585	COG0459	protein refolding
ITJ87_RS08605	COG0484	heat shock protein binding
ITJ87_RS08625	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ITJ87_RS08630	COG2086	electron transfer activity
ITJ87_RS08645	COG4667	esterase of the alpha-beta hydrolase superfamily
ITJ87_RS08650	COG1621	beta-fructofuranosidase activity
ITJ87_RS08665	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS08665	COG2205	protein histidine kinase activity
ITJ87_RS08665	COG3292	Two component regulator propeller
ITJ87_RS08690	COG1649	PFAM Uncharacterised BCR, COG1649
ITJ87_RS08695	COG1966	Carbon starvation protein
ITJ87_RS08720	COG1649	PFAM Uncharacterised BCR, COG1649
ITJ87_RS08735	COG3292	Two component regulator propeller
ITJ87_RS08735	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS08735	COG2205	protein histidine kinase activity
ITJ87_RS08745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ITJ87_RS08750	COG1280	lysine exporter protein (LysE YggA)
ITJ87_RS08765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ITJ87_RS08810	COG0511	ligase activity, forming carbon-carbon bonds
ITJ87_RS08830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS08835	COG1554	hydrolase, family 65, central catalytic
ITJ87_RS08845	COG1609	Transcriptional regulator
ITJ87_RS08855	COG3250	beta-galactosidase activity
ITJ87_RS08860	COG1629	transport
ITJ87_RS08860	COG4206	TonB-dependent receptor
ITJ87_RS08865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ITJ87_RS08875	COG2819	hydrolase of the alpha beta superfamily
ITJ87_RS08885	COG0366	Alpha amylase catalytic
ITJ87_RS08900	COG0778	Nitroreductase
ITJ87_RS08915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ITJ87_RS08920	COG0424	maF-like protein
ITJ87_RS08935	COG0126	phosphoglycerate kinase activity
ITJ87_RS08940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ITJ87_RS08950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ITJ87_RS08960	COG1629	transport
ITJ87_RS08970	COG2223	nitrite transmembrane transporter activity
ITJ87_RS09025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ITJ87_RS09030	COG1523	belongs to the glycosyl hydrolase 13 family
ITJ87_RS09035	COG1119	ATPase activity
ITJ87_RS09050	COG0671	phosphoesterase, PA-phosphatase related
ITJ87_RS09065	COG5002	protein histidine kinase activity
ITJ87_RS09070	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS09075	COG0668	transmembrane transport
ITJ87_RS09085	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITJ87_RS09100	COG3142	Participates in the control of copper homeostasis
ITJ87_RS09105	COG1418	mRNA catabolic process
ITJ87_RS09135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ITJ87_RS09140	COG2832	Protein of unknown function (DUF454)
ITJ87_RS09145	COG0351	phosphomethylpyrimidine kinase
ITJ87_RS09160	COG0602	queuosine metabolic process
ITJ87_RS09175	COG1509	lysine 2,3-aminomutase activity
ITJ87_RS09210	COG1388	LysM domain
ITJ87_RS09210	COG0741	lytic transglycosylase activity
ITJ87_RS09225	COG5002	protein histidine kinase activity
ITJ87_RS09225	COG2205	protein histidine kinase activity
ITJ87_RS09225	COG0784	Response regulator, receiver
ITJ87_RS09265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ITJ87_RS09270	COG0346	lactoylglutathione lyase activity
ITJ87_RS09275	COG0564	pseudouridine synthase activity
ITJ87_RS09280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ITJ87_RS09285	COG0542	response to heat
ITJ87_RS09290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ITJ87_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS09310	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS09315	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS09340	COG1253	flavin adenine dinucleotide binding
ITJ87_RS09365	COG0482	sulfurtransferase activity
ITJ87_RS09380	COG1757	Na H antiporter
ITJ87_RS09385	COG2814	Major facilitator Superfamily
ITJ87_RS09455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ITJ87_RS09470	COG3645	SOS response
ITJ87_RS09495	COG0582	viral genome integration into host DNA
ITJ87_RS09535	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS09550	COG0813	purine-nucleoside phosphorylase activity
ITJ87_RS09555	COG4864	UPF0365 protein
ITJ87_RS09570	COG0037	tRNA processing
ITJ87_RS09580	COG1477	protein flavinylation
ITJ87_RS09585	COG1971	Probably functions as a manganese efflux pump
ITJ87_RS09600	COG0463	Glycosyl transferase, family 2
ITJ87_RS09620	COG4206	TonB-dependent receptor
ITJ87_RS09620	COG1629	transport
ITJ87_RS09625	COG0561	phosphatase activity
ITJ87_RS09650	COG0148	phosphopyruvate hydratase activity
ITJ87_RS09655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ITJ87_RS09660	COG1082	Xylose isomerase domain protein TIM barrel
ITJ87_RS09675	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ITJ87_RS09680	COG2195	Cleaves the N-terminal amino acid of tripeptides
ITJ87_RS09685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ITJ87_RS09695	COG0254	rRNA binding
ITJ87_RS09705	COG0191	fructose-bisphosphate aldolase activity
ITJ87_RS09710	COG0366	Alpha amylase catalytic
ITJ87_RS09720	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ITJ87_RS09725	COG0511	ligase activity, forming carbon-carbon bonds
ITJ87_RS09735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ITJ87_RS09750	COG2204	response regulator
ITJ87_RS09755	COG4191	Histidine kinase
ITJ87_RS09790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ITJ87_RS09800	COG1979	alcohol dehydrogenase
ITJ87_RS09805	COG1530	ribonuclease E activity
ITJ87_RS09810	COG0776	regulation of translation
ITJ87_RS09815	COG1194	a g-specific adenine glycosylase
ITJ87_RS09820	COG0629	single-stranded DNA binding
ITJ87_RS09835	COG3033	Beta-eliminating lyase
ITJ87_RS09840	COG5002	protein histidine kinase activity
ITJ87_RS09845	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS09855	COG4771	TonB-dependent receptor
ITJ87_RS09870	COG0488	(ABC) transporter
ITJ87_RS09890	COG3591	Belongs to the peptidase S1B family
ITJ87_RS09895	COG3591	Belongs to the peptidase S1B family
ITJ87_RS09900	COG0641	radical SAM
ITJ87_RS09915	COG1408	metallophosphoesterase
ITJ87_RS09930	COG1410	methionine synthase
ITJ87_RS09930	COG0646	methionine synthase
ITJ87_RS09935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ITJ87_RS09940	COG0463	Glycosyl transferase, family 2
ITJ87_RS09945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ITJ87_RS09955	COG1032	radical SAM domain protein
ITJ87_RS09975	COG3250	beta-galactosidase activity
ITJ87_RS09980	COG0363	glucosamine-6-phosphate deaminase activity
ITJ87_RS09990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ITJ87_RS10040	COG2264	protein methyltransferase activity
ITJ87_RS10075	COG1773	rubredoxin
ITJ87_RS10075	COG1592	Rubrerythrin
ITJ87_RS10085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ITJ87_RS10085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ITJ87_RS10090	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ITJ87_RS10130	COG0698	ribose 5-phosphate isomerase
ITJ87_RS10145	COG1070	Carbohydrate kinase
ITJ87_RS10150	COG2160	L-arabinose isomerase activity
ITJ87_RS10175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ITJ87_RS10190	COG1482	cell wall glycoprotein biosynthetic process
ITJ87_RS10210	COG0513	Belongs to the DEAD box helicase family
ITJ87_RS10225	COG1218	3'(2'),5'-bisphosphate nucleotidase
ITJ87_RS10230	COG0471	metal ion transport
ITJ87_RS10230	COG3273	potassium ion transport
ITJ87_RS10235	COG0529	Catalyzes the synthesis of activated sulfate
ITJ87_RS10240	COG0175	sulfate reduction
ITJ87_RS10245	COG2895	sulfate adenylyltransferase (ATP) activity
ITJ87_RS10290	COG1477	protein flavinylation
ITJ87_RS10320	COG2095	MarC family integral membrane protein
ITJ87_RS10330	COG1830	Aldolase
ITJ87_RS10335	COG0588	phosphoglycerate mutase activity
ITJ87_RS10350	COG0205	6-phosphofructokinase activity
ITJ87_RS10355	COG4651	solute:proton antiporter activity
ITJ87_RS10355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ITJ87_RS10360	COG0058	SHG alpha-glucan phosphorylase activity
ITJ87_RS10365	COG0010	Belongs to the arginase family
ITJ87_RS10390	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS10400	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS10425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ITJ87_RS10430	COG0242	peptide deformylase activity
ITJ87_RS10440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ITJ87_RS10445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ITJ87_RS10450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ITJ87_RS10455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ITJ87_RS10460	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ITJ87_RS10465	COG1013	pyruvate-flavodoxin oxidoreductase activity
ITJ87_RS10465	COG0674	pyruvate-flavodoxin oxidoreductase activity
ITJ87_RS10465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ITJ87_RS10465	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ITJ87_RS10475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ITJ87_RS10480	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS10485	COG3507	Belongs to the glycosyl hydrolase 43 family
ITJ87_RS10520	COG0484	heat shock protein binding
ITJ87_RS10525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ITJ87_RS10530	COG0488	(ABC) transporter
ITJ87_RS10545	COG2183	response to ionizing radiation
ITJ87_RS10550	COG2205	protein histidine kinase activity
ITJ87_RS10550	COG2202	Pas domain
ITJ87_RS10565	COG4771	TonB-dependent receptor
ITJ87_RS10570	COG4977	sequence-specific DNA binding
ITJ87_RS10570	COG1917	Cupin 2, conserved barrel domain protein
ITJ87_RS10595	COG0534	Mate efflux family protein
ITJ87_RS10620	COG0586	Pfam SNARE associated Golgi protein
ITJ87_RS10630	COG0306	phosphate transporter
ITJ87_RS10640	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ITJ87_RS10650	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS10660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ITJ87_RS10670	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ITJ87_RS10675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ITJ87_RS10680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ITJ87_RS10685	COG0363	glucosamine-6-phosphate deaminase activity
ITJ87_RS10695	COG0259	pyridoxamine-phosphate oxidase activity
ITJ87_RS10760	COG3279	Response regulator of the LytR AlgR family
ITJ87_RS10770	COG1136	(ABC) transporter
ITJ87_RS10770	COG0577	efflux transmembrane transporter activity
ITJ87_RS10775	COG1136	(ABC) transporter
ITJ87_RS10805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ87_RS10815	COG0534	Mate efflux family protein
ITJ87_RS10825	COG1177	transmembrane transport
ITJ87_RS10830	COG1176	ABC-type spermidine putrescine transport system, permease component I
ITJ87_RS10835	COG3842	ATPase activity
ITJ87_RS10855	COG4221	oxidoreductase activity
ITJ87_RS10870	COG0488	(ABC) transporter
ITJ87_RS10890	COG0513	Belongs to the DEAD box helicase family
ITJ87_RS10895	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ITJ87_RS10915	COG0545	Peptidyl-prolyl cis-trans isomerase
ITJ87_RS10925	COG0534	Mate efflux family protein
ITJ87_RS10930	COG1929	Belongs to the glycerate kinase type-1 family
ITJ87_RS10935	COG1739	Uncharacterized protein family UPF0029
ITJ87_RS10955	COG1725	Transcriptional regulator
ITJ87_RS10965	COG1131	(ABC) transporter
ITJ87_RS10975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ITJ87_RS10975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ITJ87_RS10980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ITJ87_RS10985	COG0357	Ribosomal RNA small subunit methyltransferase G
ITJ87_RS11010	COG2217	Heavy metal translocating P-type atpase
ITJ87_RS11020	COG0321	lipoyl(octanoyl) transferase activity
ITJ87_RS11060	COG0110	maltose O-acetyltransferase activity
ITJ87_RS11070	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS11075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS11145	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS11150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS11160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ITJ87_RS11165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ITJ87_RS11170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ITJ87_RS11175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ITJ87_RS11195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ITJ87_RS11195	COG0072	phenylalanine-tRNA ligase activity
ITJ87_RS11200	COG0217	transcriptional regulatory protein
ITJ87_RS11210	COG1914	H( )-stimulated, divalent metal cation uptake system
ITJ87_RS11215	COG0708	Exodeoxyribonuclease III
ITJ87_RS11230	COG0481	GTPase activity
ITJ87_RS11235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ITJ87_RS11240	COG2205	protein histidine kinase activity
ITJ87_RS11240	COG0784	Response regulator, receiver
ITJ87_RS11255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ87_RS11260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ITJ87_RS11280	COG0612	Peptidase, M16
ITJ87_RS11295	COG2205	protein histidine kinase activity
ITJ87_RS11295	COG0784	Response regulator, receiver
ITJ87_RS11300	COG0463	Glycosyl transferase, family 2
ITJ87_RS11315	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITJ87_RS11320	COG1805	sodium ion transport
ITJ87_RS11325	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITJ87_RS11335	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ITJ87_RS11345	COG2233	PERMEase
ITJ87_RS11350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ITJ87_RS11360	COG0024	Methionine aminopeptidase
ITJ87_RS11370	COG0420	3'-5' exonuclease activity
ITJ87_RS11395	COG2814	Major facilitator Superfamily
ITJ87_RS11410	COG0564	pseudouridine synthase activity
ITJ87_RS11415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ITJ87_RS11420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ITJ87_RS11420	COG0574	Belongs to the PEP-utilizing enzyme family
ITJ87_RS11540	COG0784	Response regulator, receiver
ITJ87_RS11540	COG2205	protein histidine kinase activity
ITJ87_RS11540	COG5002	protein histidine kinase activity
ITJ87_RS11605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ITJ87_RS11620	COG1678	Uncharacterized ACR, COG1678
ITJ87_RS11625	COG1629	transport
ITJ87_RS11625	COG4206	TonB-dependent receptor
ITJ87_RS11645	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS11655	COG0489	protein tyrosine kinase activity
ITJ87_RS11980	COG1690	Belongs to the RtcB family
ITJ87_RS12155	COG0110	maltose O-acetyltransferase activity
ITJ87_RS12165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ITJ87_RS12180	COG0738	Major facilitator superfamily
ITJ87_RS12190	COG2059	Chromate
ITJ87_RS12200	COG3969	phosphoadenosine phosphosulfate
ITJ87_RS12205	COG1475	DNA binding
ITJ87_RS12210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ITJ87_RS12225	COG1074	ATP-dependent DNA helicase activity
ITJ87_RS12235	COG0556	nucleotide-excision repair
ITJ87_RS12240	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ITJ87_RS12270	COG3942	CHAP domain
ITJ87_RS12270	COG1388	LysM domain
ITJ87_RS12275	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ITJ87_RS12280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ITJ87_RS12285	COG3104	oligopeptide transport
ITJ87_RS12300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ITJ87_RS12310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ITJ87_RS12315	COG1695	Transcriptional regulator
ITJ87_RS12335	COG1086	Polysaccharide biosynthesis protein
ITJ87_RS12340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ITJ87_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS12380	COG2089	acid synthase
ITJ87_RS12385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ITJ87_RS12450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ITJ87_RS12455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITJ87_RS12470	COG3250	beta-galactosidase activity
ITJ87_RS12475	COG2755	lipolytic protein G-D-S-L family
ITJ87_RS12475	COG0657	acetylesterase activity
ITJ87_RS12500	COG3059	membrane
ITJ87_RS12505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITJ87_RS12520	COG1120	ATPase activity
ITJ87_RS12525	COG0534	Mate efflux family protein
ITJ87_RS12530	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ITJ87_RS12540	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ITJ87_RS12570	COG4771	TonB-dependent receptor
ITJ87_RS12615	COG0439	Biotin carboxylase
ITJ87_RS12625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ITJ87_RS12635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ITJ87_RS12645	COG1797	cobyrinic acid a,c-diamide synthase activity
ITJ87_RS12685	COG2096	Adenosyltransferase
ITJ87_RS12690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ITJ87_RS12710	COG1492	cobalamin metabolic process
ITJ87_RS12720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ITJ87_RS12745	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ITJ87_RS12760	COG0442	prolyl-tRNA aminoacylation
ITJ87_RS12830	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS12845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ITJ87_RS12850	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ITJ87_RS12855	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS12870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ITJ87_RS12875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ITJ87_RS12885	COG1506	peptidase
ITJ87_RS12885	COG0823	Involved in the tonB-independent uptake of proteins
ITJ87_RS12890	COG0534	Mate efflux family protein
ITJ87_RS12900	COG0504	CTP synthase activity
ITJ87_RS12920	COG4656	Part of a membrane complex involved in electron transport
ITJ87_RS12925	COG4658	electron transport chain
ITJ87_RS12930	COG4659	FMN binding
ITJ87_RS12935	COG4660	Part of a membrane complex involved in electron transport
ITJ87_RS12940	COG4657	Part of a membrane complex involved in electron transport
ITJ87_RS12945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ITJ87_RS12965	COG0356	it plays a direct role in the translocation of protons across the membrane
ITJ87_RS12970	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ITJ87_RS12975	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ITJ87_RS12980	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ITJ87_RS12985	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ITJ87_RS12990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ITJ87_RS12995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ITJ87_RS13030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ITJ87_RS13040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ITJ87_RS13045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ITJ87_RS13060	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ITJ87_RS13065	COG0540	Belongs to the ATCase OTCase family
ITJ87_RS13070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ITJ87_RS13080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ITJ87_RS13095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ITJ87_RS13100	COG2205	protein histidine kinase activity
ITJ87_RS13140	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ITJ87_RS13180	COG0351	phosphomethylpyrimidine kinase
ITJ87_RS13185	COG0352	thiamine-phosphate diphosphorylase activity
ITJ87_RS13200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ITJ87_RS13205	COG2022	thiamine diphosphate biosynthetic process
ITJ87_RS13210	COG0352	thiamine-phosphate diphosphorylase activity
ITJ87_RS13220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ITJ87_RS13230	COG1070	Carbohydrate kinase
ITJ87_RS13235	COG2115	Belongs to the xylose isomerase family
ITJ87_RS13240	COG0477	Major facilitator Superfamily
ITJ87_RS13240	COG2814	Major facilitator Superfamily
ITJ87_RS13250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ITJ87_RS13250	COG3153	acetyltransferase
ITJ87_RS13260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ITJ87_RS13270	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ITJ87_RS13285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITJ87_RS13315	COG2194	sulfuric ester hydrolase activity
ITJ87_RS13335	COG3387	PFAM Glycoside hydrolase 15-related
ITJ87_RS13345	COG2249	NAD(P)H dehydrogenase (quinone) activity
ITJ87_RS13365	COG1132	(ABC) transporter
ITJ87_RS13430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ITJ87_RS13445	COG1904	glucuronate isomerase
ITJ87_RS13450	COG1609	Transcriptional regulator
ITJ87_RS13455	COG0246	Mannitol dehydrogenase
ITJ87_RS13490	COG0513	Belongs to the DEAD box helicase family
ITJ87_RS13495	COG0560	Phosphoserine phosphatase
ITJ87_RS13495	COG3830	Belongs to the UPF0237 family
ITJ87_RS13510	COG0343	queuine tRNA-ribosyltransferase activity
ITJ87_RS13515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ITJ87_RS13520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ITJ87_RS13765	COG0358	DNA primase activity
ITJ87_RS13850	COG1136	(ABC) transporter
ITJ87_RS13865	COG0501	Belongs to the peptidase M48B family
ITJ87_RS13870	COG0156	8-amino-7-oxononanoate synthase activity
ITJ87_RS13875	COG1597	lipid kinase activity
ITJ87_RS13880	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ITJ87_RS13895	COG2957	Belongs to the agmatine deiminase family
ITJ87_RS13905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ITJ87_RS13910	COG0390	transport system, permease component
ITJ87_RS13915	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ITJ87_RS13960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ITJ87_RS13975	COG0543	2 iron, 2 sulfur cluster binding
ITJ87_RS13980	COG0167	dihydroorotate dehydrogenase activity
ITJ87_RS13985	COG0336	Belongs to the RNA methyltransferase TrmD family
ITJ87_RS13990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ITJ87_RS13995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ITJ87_RS14020	COG0542	response to heat
ITJ87_RS14025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ITJ87_RS14065	COG2304	oxidoreductase activity
ITJ87_RS14080	COG0714	Associated with various cellular activities
ITJ87_RS14095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ITJ87_RS14100	COG0552	protein localization to endoplasmic reticulum
ITJ87_RS14110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ITJ87_RS14115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ITJ87_RS14120	COG1058	Belongs to the CinA family
ITJ87_RS14120	COG1546	Belongs to the CinA family
ITJ87_RS14125	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ITJ87_RS14135	COG0305	Participates in initiation and elongation during chromosome replication
ITJ87_RS14140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ITJ87_RS14150	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ITJ87_RS14160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ITJ87_RS14165	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ITJ87_RS14175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ITJ87_RS14180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITJ87_RS14185	COG0534	Mate efflux family protein
ITJ87_RS14195	COG1136	(ABC) transporter
ITJ87_RS14195	COG0577	efflux transmembrane transporter activity
ITJ87_RS14200	COG1136	(ABC) transporter
ITJ87_RS14225	COG2205	protein histidine kinase activity
ITJ87_RS14230	COG3263	regulation of cellular component size
ITJ87_RS14235	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS14240	COG1082	Xylose isomerase domain protein TIM barrel
ITJ87_RS14260	COG0702	epimerase
ITJ87_RS14265	COG4771	TonB-dependent receptor
ITJ87_RS14300	COG1752	Esterase of the alpha-beta hydrolase superfamily
ITJ87_RS14335	COG3344	reverse transcriptase
ITJ87_RS14350	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ87_RS14350	COG0551	DNA topoisomerase type I activity
ITJ87_RS14385	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS14400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ITJ87_RS14410	COG2755	lipolytic protein G-D-S-L family
ITJ87_RS14410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ITJ87_RS14420	COG0842	Transport permease protein
ITJ87_RS14425	COG1131	(ABC) transporter
ITJ87_RS14440	COG1917	Cupin 2, conserved barrel domain protein
ITJ87_RS14440	COG2207	Transcriptional regulator
ITJ87_RS14445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ITJ87_RS14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS14455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ITJ87_RS14460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ITJ87_RS14465	COG0505	Belongs to the CarA family
ITJ87_RS14475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ITJ87_RS14480	COG0067	glutamate synthase
ITJ87_RS14480	COG0069	glutamate synthase activity
ITJ87_RS14480	COG0070	glutamate synthase
ITJ87_RS14490	COG0367	asparagine synthase
ITJ87_RS14505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ITJ87_RS14510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ITJ87_RS14545	COG1442	glycosyl transferase family 8
ITJ87_RS14545	COG1216	Glycosyl transferase, family 2
ITJ87_RS14555	COG0438	transferase activity, transferring glycosyl groups
ITJ87_RS14565	COG0110	maltose O-acetyltransferase activity
ITJ87_RS14570	COG2244	polysaccharide biosynthetic process
ITJ87_RS14625	COG0436	Aminotransferase
ITJ87_RS14655	COG0133	tryptophan synthase activity
ITJ87_RS14660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ITJ87_RS14665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ITJ87_RS14665	COG0512	Glutamine amidotransferase of anthranilate synthase
ITJ87_RS14670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ITJ87_RS14675	COG0134	indole-3-glycerol-phosphate synthase activity
ITJ87_RS14680	COG0135	phosphoribosylanthranilate isomerase activity
ITJ87_RS14685	COG0159	tryptophan synthase activity
ITJ87_RS14690	COG0252	asparaginase activity
ITJ87_RS14700	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS14780	COG1442	glycosyl transferase family 8
ITJ87_RS14780	COG1216	Glycosyl transferase, family 2
ITJ87_RS14785	COG1216	Glycosyl transferase, family 2
ITJ87_RS14790	COG1216	Glycosyl transferase, family 2
ITJ87_RS14820	COG1609	Transcriptional regulator
ITJ87_RS14825	COG2721	sulfolactate sulfo-lyase activity
ITJ87_RS14835	COG0228	four-way junction DNA binding
ITJ87_RS14840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ITJ87_RS14870	COG0588	phosphoglycerate mutase activity
ITJ87_RS14880	COG0716	FMN binding
ITJ87_RS14885	COG0058	SHG alpha-glucan phosphorylase activity
ITJ87_RS14915	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ITJ87_RS15220	COG0305	Participates in initiation and elongation during chromosome replication
ITJ87_RS15245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ITJ87_RS15245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ITJ87_RS15260	COG2226	methyltransferase
ITJ87_RS15270	COG1215	transferase activity, transferring glycosyl groups
ITJ87_RS15275	COG4591	ABC-type transport system involved in lipoprotein release permease component
ITJ87_RS15280	COG0436	Aminotransferase
ITJ87_RS15290	COG0784	Response regulator, receiver
ITJ87_RS15290	COG2205	protein histidine kinase activity
ITJ87_RS15320	COG0577	efflux transmembrane transporter activity
ITJ87_RS15335	COG0577	efflux transmembrane transporter activity
ITJ87_RS15340	COG1136	(ABC) transporter
ITJ87_RS15345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ITJ87_RS15350	COG3942	CHAP domain
ITJ87_RS15350	COG1705	Flagellar rod assembly protein muramidase FlgJ
ITJ87_RS15355	COG0295	cytidine deaminase activity
ITJ87_RS15360	COG0488	(ABC) transporter
ITJ87_RS15365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ITJ87_RS15390	COG0714	Associated with various cellular activities
ITJ87_RS15405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ITJ87_RS15415	COG0739	heme binding
ITJ87_RS15420	COG0686	Belongs to the AlaDH PNT family
ITJ87_RS15430	COG0076	glutamate decarboxylase activity
ITJ87_RS15435	COG2066	Belongs to the glutaminase family
ITJ87_RS15445	COG0531	amino acid
ITJ87_RS15470	COG1595	DNA-templated transcription, initiation
ITJ87_RS15495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ITJ87_RS15520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ITJ87_RS15525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ITJ87_RS15535	COG4948	Mandelate Racemase Muconate Lactonizing
ITJ87_RS15560	COG0778	Nitroreductase
ITJ87_RS15570	COG0704	Plays a role in the regulation of phosphate uptake
ITJ87_RS15575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ITJ87_RS15580	COG0581	inorganic phosphate transmembrane transporter activity
ITJ87_RS15585	COG0573	inorganic phosphate transmembrane transporter activity
ITJ87_RS15590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ITJ87_RS15595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ITJ87_RS15605	COG0586	Pfam SNARE associated Golgi protein
ITJ87_RS15610	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ITJ87_RS15625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ITJ87_RS15630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ITJ87_RS15635	COG0656	L-ascorbic acid biosynthetic process
ITJ87_RS15645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS15650	COG0318	PFAM AMP-dependent synthetase and ligase
ITJ87_RS15660	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS15665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS15680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ITJ87_RS15690	COG1216	Glycosyl transferase, family 2
ITJ87_RS15730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ITJ87_RS15735	COG0167	dihydroorotate dehydrogenase activity
ITJ87_RS15745	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ITJ87_RS15765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ITJ87_RS15770	COG0497	DNA recombination
ITJ87_RS15785	COG0592	DNA-directed DNA polymerase activity
ITJ87_RS15800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ITJ87_RS15800	COG0321	lipoyl(octanoyl) transferase activity
ITJ87_RS15805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ITJ87_RS15820	COG0156	8-amino-7-oxononanoate synthase activity
ITJ87_RS15830	COG0019	diaminopimelate decarboxylase activity
ITJ87_RS15835	COG0527	aspartate kinase activity
ITJ87_RS15840	COG2884	Cell division ATP-binding protein ftsE
ITJ87_RS15845	COG0140	phosphoribosyl-ATP diphosphatase activity
ITJ87_RS15845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ITJ87_RS15850	COG0107	imidazoleglycerol-phosphate synthase activity
ITJ87_RS15855	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ITJ87_RS15860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ITJ87_RS15865	COG0788	formyltetrahydrofolate deformylase activity
ITJ87_RS15885	COG0561	phosphatase activity
ITJ87_RS15890	COG2207	Transcriptional regulator
ITJ87_RS15890	COG1609	Transcriptional regulator
ITJ87_RS15900	COG0714	Associated with various cellular activities
ITJ87_RS15935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ITJ87_RS15950	COG1151	hydroxylamine reductase activity
ITJ87_RS15975	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ITJ87_RS15980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ITJ87_RS15990	COG1629	transport
ITJ87_RS15995	COG0702	epimerase
ITJ87_RS16020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ITJ87_RS16025	COG1741	Belongs to the pirin family
ITJ87_RS16040	COG0346	lactoylglutathione lyase activity
ITJ87_RS16065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ITJ87_RS16065	COG1918	ferrous iron import across plasma membrane
ITJ87_RS16070	COG0037	tRNA processing
ITJ87_RS16085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ITJ87_RS16090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ITJ87_RS16115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ITJ87_RS16125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ITJ87_RS16145	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16210	COG0551	DNA topoisomerase type I activity
ITJ87_RS16210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ87_RS16360	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ITJ87_RS16500	COG0551	DNA topoisomerase type I activity
ITJ87_RS16500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ87_RS16640	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16655	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16660	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16665	COG4974	Belongs to the 'phage' integrase family
ITJ87_RS16710	COG0210	DNA helicase
ITJ87_RS16720	COG1193	negative regulation of DNA recombination
ITJ87_RS16725	COG1760	l-serine dehydratase
ITJ87_RS16740	COG5002	protein histidine kinase activity
ITJ87_RS16740	COG3850	Histidine kinase
ITJ87_RS16745	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS16795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ITJ87_RS16800	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ITJ87_RS16835	COG4139	cobalamin transport
ITJ87_RS16875	COG2271	Major facilitator Superfamily
ITJ87_RS16945	COG1196	nuclear chromosome segregation
ITJ87_RS16970	COG0443	Heat shock 70 kDa protein
ITJ87_RS16995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ITJ87_RS17000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ITJ87_RS17015	COG1595	DNA-templated transcription, initiation
ITJ87_RS17035	COG2855	membrane
ITJ87_RS17040	COG0583	DNA-binding transcription factor activity
ITJ87_RS17050	COG0542	response to heat
ITJ87_RS17060	COG0237	dephospho-CoA kinase activity
ITJ87_RS17070	COG1862	Preprotein translocase
ITJ87_RS17075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ITJ87_RS17085	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ITJ87_RS17090	COG0193	aminoacyl-tRNA hydrolase activity
ITJ87_RS17095	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ITJ87_RS17100	COG0673	inositol 2-dehydrogenase activity
ITJ87_RS17105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ITJ87_RS17105	COG4651	solute:proton antiporter activity
ITJ87_RS17110	COG0131	Imidazoleglycerol-phosphate dehydratase
ITJ87_RS17115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ITJ87_RS17120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ITJ87_RS17125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ITJ87_RS17150	COG4232	protein-disulfide reductase activity
ITJ87_RS17160	COG0572	uridine kinase
ITJ87_RS17165	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ITJ87_RS17170	COG1410	methionine synthase
ITJ87_RS17170	COG0646	methionine synthase
ITJ87_RS17175	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ITJ87_RS17210	COG3328	transposase activity
ITJ87_RS17255	COG1063	alcohol dehydrogenase
ITJ87_RS17300	COG0534	Mate efflux family protein
ITJ87_RS17305	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ITJ87_RS17310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITJ87_RS17325	COG2217	Heavy metal translocating P-type atpase
ITJ87_RS17410	COG1472	Belongs to the glycosyl hydrolase 3 family
ITJ87_RS17415	COG2706	6-phosphogluconolactonase activity
ITJ87_RS17455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ITJ87_RS17465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ITJ87_RS17475	COG1253	flavin adenine dinucleotide binding
ITJ87_RS17505	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
ITJ87_RS17510	COG0653	protein targeting
ITJ87_RS17540	COG0561	phosphatase activity
ITJ87_RS17545	COG4771	TonB-dependent receptor
ITJ87_RS17575	COG0525	valine-tRNA ligase activity
ITJ87_RS17585	COG3956	TIGRFAM MazG family protein
ITJ87_RS17605	COG1234	tRNA 3'-trailer cleavage
ITJ87_RS17645	COG0492	ferredoxin-NADP+ reductase activity
ITJ87_RS17655	COG1674	ftsk spoiiie
ITJ87_RS17675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ITJ87_RS17680	COG3250	beta-galactosidase activity
ITJ87_RS17690	COG4771	TonB-dependent receptor
ITJ87_RS17735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ITJ87_RS17740	COG2211	Major facilitator Superfamily
ITJ87_RS17760	COG1136	(ABC) transporter
ITJ87_RS17775	COG0471	metal ion transport
ITJ87_RS17775	COG0490	domain, Protein
ITJ87_RS17790	COG1733	regulation of RNA biosynthetic process
ITJ87_RS17805	COG2207	Transcriptional regulator
ITJ87_RS17805	COG1917	Cupin 2, conserved barrel domain protein
ITJ87_RS17820	COG2873	o-acetylhomoserine
ITJ87_RS17835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ITJ87_RS17850	COG0702	epimerase
ITJ87_RS17855	COG4771	TonB-dependent receptor
ITJ87_RS17870	COG3119	arylsulfatase activity
ITJ87_RS17875	COG3537	Alpha-1,2-mannosidase
ITJ87_RS17885	COG1940	carbohydrate kinase activity
ITJ87_RS17895	COG2188	Transcriptional regulator
ITJ87_RS17900	COG0523	cobalamin synthesis protein
ITJ87_RS17905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ITJ87_RS17910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ITJ87_RS17920	COG0194	GDP metabolic process
ITJ87_RS17930	COG1214	PFAM Peptidase M22, glycoprotease
ITJ87_RS17940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ITJ87_RS17945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ITJ87_RS17955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ITJ87_RS17960	COG0750	zinc metalloprotease
ITJ87_RS17965	COG0673	inositol 2-dehydrogenase activity
ITJ87_RS17970	COG0632	four-way junction helicase activity
ITJ87_RS17980	COG0006	proline dipeptidase activity
ITJ87_RS17990	COG1082	Xylose isomerase domain protein TIM barrel
ITJ87_RS18010	COG4771	TonB-dependent receptor
ITJ87_RS18035	COG4771	TonB-dependent receptor
ITJ87_RS18050	COG0363	glucosamine-6-phosphate deaminase activity
ITJ87_RS18055	COG1940	carbohydrate kinase activity
ITJ87_RS18060	COG3292	Two component regulator propeller
ITJ87_RS18060	COG0745	RESPONSE REGULATOR receiver
ITJ87_RS18060	COG2205	protein histidine kinase activity
ITJ87_RS18070	COG1408	metallophosphoesterase
ITJ87_RS18075	COG1575	Belongs to the MenA family. Type 1 subfamily
ITJ87_RS18085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ITJ87_RS18095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ITJ87_RS18105	COG0617	tRNA 3'-terminal CCA addition
ITJ87_RS18115	COG2204	response regulator
ITJ87_RS18120	COG0488	(ABC) transporter
ITJ87_RS18125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ITJ87_RS18160	COG4771	TonB-dependent receptor
ITJ87_RS18175	COG1595	DNA-templated transcription, initiation
ITJ87_RS18190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ITJ87_RS18195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ITJ87_RS18200	COG1522	sequence-specific DNA binding
ITJ87_RS18230	COG0811	peptide transport
ITJ87_RS18240	COG0084	hydrolase, TatD family'
ITJ87_RS18260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ITJ87_RS18265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ITJ87_RS18270	COG0205	6-phosphofructokinase activity
ITJ87_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
ITJ87_RS18290	COG0372	Belongs to the citrate synthase family
ITJ87_RS18305	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ITJ87_RS18310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ITJ87_RS18320	COG0440	acetolactate synthase activity
ITJ87_RS18330	COG0129	dihydroxy-acid dehydratase activity
ITJ87_RS18335	COG1047	Peptidyl-prolyl cis-trans
ITJ87_RS18340	COG3681	Belongs to the UPF0597 family
ITJ87_RS18370	COG0551	DNA topoisomerase type I activity
ITJ87_RS18370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ITJ87_RS18375	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ITJ87_RS18375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ITJ87_RS18380	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ITJ87_RS18385	COG0569	domain protein
ITJ87_RS18385	COG2985	domain, Protein
ITJ87_RS18405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ITJ87_RS18410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ITJ87_RS18415	COG0166	Belongs to the GPI family
ITJ87_RS18420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ITJ87_RS18440	COG0789	Transcriptional regulator
ITJ87_RS18450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ITJ87_RS18460	COG2502	aspartate--ammonia ligase
ITJ87_RS18465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ITJ87_RS18480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ITJ87_RS18490	COG0463	Glycosyl transferase, family 2
ITJ87_RS18520	COG0860	N-Acetylmuramoyl-L-alanine amidase