locus-tag	class	description
GD631_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GD631_RS00010	COG0778	Nitroreductase
GD631_RS00020	COG1640	4-alpha-glucanotransferase
GD631_RS00030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GD631_RS00040	COG1216	Glycosyl transferase, family 2
GD631_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GD631_RS00055	COG1022	Amp-dependent synthetase and ligase
GD631_RS00090	COG0359	binds to the 23S rRNA
GD631_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GD631_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
GD631_RS00125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GD631_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GD631_RS00165	COG2431	L-lysine efflux transmembrane transporter activity
GD631_RS00200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GD631_RS00220	COG2234	aminopeptidase activity
GD631_RS00230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GD631_RS00235	COG0802	atpase or kinase
GD631_RS00250	COG0714	Associated with various cellular activities
GD631_RS00285	COG3118	belongs to the thioredoxin family
GD631_RS00290	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS00315	COG2017	converts alpha-aldose to the beta-anomer
GD631_RS00320	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS00330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS00335	COG1082	Xylose isomerase domain protein TIM barrel
GD631_RS00355	COG1629	transport
GD631_RS00355	COG4206	TonB-dependent receptor
GD631_RS00360	COG4948	Mandelate Racemase Muconate Lactonizing
GD631_RS00365	COG0457	Tetratricopeptide repeat
GD631_RS00370	COG2814	Major facilitator Superfamily
GD631_RS00370	COG0477	Major facilitator Superfamily
GD631_RS00385	COG0688	phosphatidylethanolamine metabolic process
GD631_RS00390	COG1183	phosphatidylcholine synthase activity
GD631_RS00410	COG0792	nuclease activity
GD631_RS00435	COG0534	Mate efflux family protein
GD631_RS00440	COG0528	UMP kinase activity
GD631_RS00445	COG3292	Two component regulator propeller
GD631_RS00445	COG2205	protein histidine kinase activity
GD631_RS00445	COG0745	RESPONSE REGULATOR receiver
GD631_RS00495	COG0702	epimerase
GD631_RS00500	COG4771	TonB-dependent receptor
GD631_RS00510	COG1629	transport
GD631_RS00525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD631_RS00530	COG3693	PFAM glycoside hydrolase, family 10
GD631_RS00540	COG3250	beta-galactosidase activity
GD631_RS00550	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS00565	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS00575	COG4677	pectinesterase activity
GD631_RS00585	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS00615	COG3250	beta-galactosidase activity
GD631_RS00625	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GD631_RS00630	COG1629	transport
GD631_RS00635	COG2205	protein histidine kinase activity
GD631_RS00635	COG0745	RESPONSE REGULATOR receiver
GD631_RS00635	COG3292	Two component regulator propeller
GD631_RS00640	COG0697	spore germination
GD631_RS00645	COG0233	cytoplasmic translational termination
GD631_RS00650	COG1162	GTPase activity
GD631_RS00660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GD631_RS00675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GD631_RS00675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GD631_RS00685	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GD631_RS00695	COG4206	TonB-dependent receptor
GD631_RS00695	COG1629	transport
GD631_RS00700	COG4974	Belongs to the 'phage' integrase family
GD631_RS00705	COG1629	transport
GD631_RS00705	COG4206	TonB-dependent receptor
GD631_RS00720	COG2095	MarC family integral membrane protein
GD631_RS00735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GD631_RS00745	COG1435	thymidine kinase activity
GD631_RS00750	COG0628	permease
GD631_RS00850	COG1396	sequence-specific DNA binding
GD631_RS00910	COG2076	Multidrug Resistance protein
GD631_RS00930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS00935	COG1484	DNA-dependent DNA replication
GD631_RS00950	COG3250	beta-galactosidase activity
GD631_RS00955	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GD631_RS00960	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS00975	COG3408	Glycogen debranching enzyme
GD631_RS00985	COG0702	epimerase
GD631_RS00990	COG1629	transport
GD631_RS01005	COG1595	DNA-templated transcription, initiation
GD631_RS01020	COG1733	regulation of RNA biosynthetic process
GD631_RS01030	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GD631_RS01040	COG0589	response to stress
GD631_RS01040	COG0475	glutathione-regulated potassium exporter activity
GD631_RS01085	COG5520	Belongs to the glycosyl hydrolase 30 family
GD631_RS01095	COG4206	TonB-dependent receptor
GD631_RS01095	COG1629	transport
GD631_RS01105	COG3250	beta-galactosidase activity
GD631_RS01110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS01135	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS01140	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GD631_RS01165	COG0534	Mate efflux family protein
GD631_RS01175	COG0110	maltose O-acetyltransferase activity
GD631_RS01180	COG1522	sequence-specific DNA binding
GD631_RS01185	COG2873	o-acetylhomoserine
GD631_RS01195	COG0668	transmembrane transport
GD631_RS01220	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
GD631_RS01225	COG0527	aspartate kinase activity
GD631_RS01225	COG0460	homoserine dehydrogenase
GD631_RS01230	COG0252	asparaginase activity
GD631_RS01240	COG1106	Psort location Cytoplasmic, score
GD631_RS01245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GD631_RS01250	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GD631_RS01260	COG4771	TonB-dependent receptor
GD631_RS01275	COG0826	peptidase U32
GD631_RS01280	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GD631_RS01295	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GD631_RS01345	COG3617	BRO family, N-terminal domain
GD631_RS01370	COG4974	Belongs to the 'phage' integrase family
GD631_RS01380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GD631_RS01385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GD631_RS01390	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GD631_RS01410	COG1629	transport
GD631_RS01410	COG4206	TonB-dependent receptor
GD631_RS01420	COG2197	response regulator
GD631_RS01425	COG0519	Catalyzes the synthesis of GMP from XMP
GD631_RS01445	COG4206	TonB-dependent receptor
GD631_RS01445	COG1629	transport
GD631_RS01475	COG4771	TonB-dependent receptor
GD631_RS01485	COG1131	(ABC) transporter
GD631_RS01500	COG5002	protein histidine kinase activity
GD631_RS01505	COG2205	protein histidine kinase activity
GD631_RS01515	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GD631_RS01520	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GD631_RS01525	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GD631_RS01575	COG4263	nitrous-oxide reductase activity
GD631_RS01590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GD631_RS01600	COG4948	Mandelate Racemase Muconate Lactonizing
GD631_RS01630	COG4771	TonB-dependent receptor
GD631_RS01645	COG0471	metal ion transport
GD631_RS01655	COG3292	Two component regulator propeller
GD631_RS01655	COG2205	protein histidine kinase activity
GD631_RS01655	COG0745	RESPONSE REGULATOR receiver
GD631_RS01685	COG4771	TonB-dependent receptor
GD631_RS01710	COG0616	signal peptide processing
GD631_RS01715	COG1663	tetraacyldisaccharide 4'-kinase activity
GD631_RS01720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GD631_RS01725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GD631_RS01745	COG4974	Belongs to the 'phage' integrase family
GD631_RS01800	COG0546	phosphoglycolate phosphatase activity
GD631_RS01805	COG0110	maltose O-acetyltransferase activity
GD631_RS01835	COG0513	Belongs to the DEAD box helicase family
GD631_RS01840	COG2070	2-Nitropropane dioxygenase
GD631_RS01845	COG0724	RNA recognition motif
GD631_RS01850	COG2197	response regulator
GD631_RS01860	COG3973	AAA domain
GD631_RS01905	COG2204	response regulator
GD631_RS01910	COG0446	pyridine nucleotide-disulphide oxidoreductase
GD631_RS01930	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS01935	COG0737	Belongs to the 5'-nucleotidase family
GD631_RS01940	COG0737	Belongs to the 5'-nucleotidase family
GD631_RS01945	COG0335	large ribosomal subunit rRNA binding
GD631_RS01955	COG1136	(ABC) transporter
GD631_RS01955	COG0577	efflux transmembrane transporter activity
GD631_RS01960	COG1136	(ABC) transporter
GD631_RS01960	COG0577	efflux transmembrane transporter activity
GD631_RS01965	COG1136	(ABC) transporter
GD631_RS01965	COG0577	efflux transmembrane transporter activity
GD631_RS01980	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GD631_RS01980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GD631_RS01990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD631_RS02010	COG2996	Protein conserved in bacteria
GD631_RS02015	COG0039	L-malate dehydrogenase activity
GD631_RS02025	COG2217	Heavy metal translocating P-type atpase
GD631_RS02040	COG3250	beta-galactosidase activity
GD631_RS02055	COG4771	TonB-dependent receptor
GD631_RS02070	COG0745	RESPONSE REGULATOR receiver
GD631_RS02070	COG2205	protein histidine kinase activity
GD631_RS02070	COG3292	Two component regulator propeller
GD631_RS02080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GD631_RS02085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GD631_RS02090	COG0509	glycine decarboxylation via glycine cleavage system
GD631_RS02105	COG0006	proline dipeptidase activity
GD631_RS02110	COG3458	cephalosporin-C deacetylase activity
GD631_RS02125	COG1283	sodium-dependent phosphate transmembrane transporter activity
GD631_RS02130	COG1773	rubredoxin
GD631_RS02140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GD631_RS02145	COG1011	Hydrolase
GD631_RS02150	COG0196	riboflavin kinase activity
GD631_RS02155	COG1266	CAAX protease self-immunity
GD631_RS02165	COG0612	Peptidase, M16
GD631_RS02180	COG4206	TonB-dependent receptor
GD631_RS02180	COG1629	transport
GD631_RS02185	COG2166	iron-sulfur cluster assembly
GD631_RS02190	COG2234	aminopeptidase activity
GD631_RS02195	COG1619	proteins homologs of microcin C7 resistance protein MccF
GD631_RS02200	COG0280	phosphate acetyltransferase
GD631_RS02205	COG3426	butyrate kinase activity
GD631_RS02225	COG1185	polyribonucleotide nucleotidyltransferase activity
GD631_RS02235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GD631_RS02255	COG0076	glutamate decarboxylase activity
GD631_RS02260	COG2066	Belongs to the glutaminase family
GD631_RS02270	COG0531	amino acid
GD631_RS02275	COG2205	protein histidine kinase activity
GD631_RS02275	COG3850	Histidine kinase
GD631_RS02275	COG3437	response regulator, receiver
GD631_RS02275	COG4999	Histidine kinase
GD631_RS02290	COG3345	alpha-galactosidase
GD631_RS02310	COG1131	(ABC) transporter
GD631_RS02380	COG0667	Aldo Keto reductase
GD631_RS02385	COG1696	Membrane protein involved in D-alanine export
GD631_RS02410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS02420	COG1309	transcriptional regulator
GD631_RS02425	COG2986	histidine ammonia-lyase
GD631_RS02435	COG1228	amidohydrolase
GD631_RS02445	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GD631_RS02455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GD631_RS02470	COG0203	ribosomal protein L17
GD631_RS02475	COG0202	RNA polymerase activity
GD631_RS02480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GD631_RS02485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GD631_RS02490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GD631_RS02495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GD631_RS02500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GD631_RS02515	COG0200	Binds to the 23S rRNA
GD631_RS02520	COG1841	ribosomal large subunit assembly
GD631_RS02525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GD631_RS02530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GD631_RS02535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GD631_RS02540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GD631_RS02545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GD631_RS02550	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GD631_RS02555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GD631_RS02560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GD631_RS02565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GD631_RS02570	COG0255	Belongs to the universal ribosomal protein uL29 family
GD631_RS02575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GD631_RS02580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GD631_RS02585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GD631_RS02590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GD631_RS02595	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GD631_RS02600	COG0089	rRNA binding
GD631_RS02605	COG0088	Forms part of the polypeptide exit tunnel
GD631_RS02610	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GD631_RS02615	COG0051	transcription antitermination factor activity, RNA binding
GD631_RS02620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GD631_RS02625	COG0049	tRNA binding
GD631_RS02630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GD631_RS02640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GD631_RS02645	COG0085	RNA polymerase activity
GD631_RS02650	COG0222	ribosome binding
GD631_RS02655	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GD631_RS02660	COG0081	regulation of translation
GD631_RS02665	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GD631_RS02675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GD631_RS02685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GD631_RS02715	COG4974	Belongs to the 'phage' integrase family
GD631_RS02720	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GD631_RS02725	COG0006	proline dipeptidase activity
GD631_RS02730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GD631_RS02750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GD631_RS02760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GD631_RS02770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GD631_RS02785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GD631_RS02790	COG1027	Aspartate ammonia-lyase
GD631_RS02795	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GD631_RS02800	COG0252	asparaginase activity
GD631_RS02880	COG2096	Adenosyltransferase
GD631_RS02915	COG0662	Cupin 2, conserved barrel domain protein
GD631_RS02915	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GD631_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
GD631_RS02925	COG1396	sequence-specific DNA binding
GD631_RS02930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GD631_RS02935	COG1217	gtp-binding protein TYPA
GD631_RS02945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GD631_RS02950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GD631_RS02985	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GD631_RS02990	COG0784	Response regulator, receiver
GD631_RS02990	COG2205	protein histidine kinase activity
GD631_RS02990	COG5002	protein histidine kinase activity
GD631_RS03000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD631_RS03015	COG1040	competence protein
GD631_RS03035	COG0457	Tetratricopeptide repeat
GD631_RS03060	COG4771	TonB-dependent receptor
GD631_RS03105	COG2610	gluconate transmembrane transporter activity
GD631_RS03110	COG1929	Belongs to the glycerate kinase type-1 family
GD631_RS03130	COG1629	transport
GD631_RS03155	COG4771	TonB-dependent receptor
GD631_RS03165	COG2205	protein histidine kinase activity
GD631_RS03165	COG3292	Two component regulator propeller
GD631_RS03165	COG0745	RESPONSE REGULATOR receiver
GD631_RS03180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD631_RS03185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD631_RS03190	COG1629	transport
GD631_RS03195	COG0702	epimerase
GD631_RS03205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GD631_RS03210	COG2731	YhcH YjgK YiaL family protein
GD631_RS03215	COG2814	Major facilitator Superfamily
GD631_RS03245	COG4771	TonB-dependent receptor
GD631_RS03250	COG2205	protein histidine kinase activity
GD631_RS03250	COG3292	Two component regulator propeller
GD631_RS03250	COG0745	RESPONSE REGULATOR receiver
GD631_RS03310	COG0018	arginyl-trna synthetase
GD631_RS03320	COG0705	Rhomboid family
GD631_RS03335	COG0339	signal peptide processing
GD631_RS03340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GD631_RS03350	COG0674	pyruvate-flavodoxin oxidoreductase activity
GD631_RS03350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GD631_RS03355	COG1013	pyruvate-flavodoxin oxidoreductase activity
GD631_RS03360	COG4591	ABC-type transport system involved in lipoprotein release permease component
GD631_RS03365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GD631_RS03385	COG4974	Belongs to the 'phage' integrase family
GD631_RS03400	COG0606	chelatase, subunit chli
GD631_RS03405	COG2205	protein histidine kinase activity
GD631_RS03415	COG0702	epimerase
GD631_RS03420	COG4771	TonB-dependent receptor
GD631_RS03430	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS03435	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS03455	COG4771	TonB-dependent receptor
GD631_RS03475	COG2205	protein histidine kinase activity
GD631_RS03475	COG0745	RESPONSE REGULATOR receiver
GD631_RS03475	COG3292	Two component regulator propeller
GD631_RS03480	COG0582	viral genome integration into host DNA
GD631_RS03515	COG0673	inositol 2-dehydrogenase activity
GD631_RS03520	COG0673	inositol 2-dehydrogenase activity
GD631_RS03530	COG0745	RESPONSE REGULATOR receiver
GD631_RS03530	COG2205	protein histidine kinase activity
GD631_RS03530	COG3292	Two component regulator propeller
GD631_RS03570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GD631_RS03570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GD631_RS03585	COG3475	LICD family
GD631_RS03600	COG0438	transferase activity, transferring glycosyl groups
GD631_RS03630	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GD631_RS03635	COG0545	Peptidyl-prolyl cis-trans isomerase
GD631_RS03640	COG0545	Peptidyl-prolyl cis-trans isomerase
GD631_RS03690	COG0561	phosphatase activity
GD631_RS03755	COG4771	TonB-dependent receptor
GD631_RS03760	COG0702	epimerase
GD631_RS03770	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GD631_RS03780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GD631_RS03790	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GD631_RS03795	COG2211	Major facilitator Superfamily
GD631_RS03800	COG3408	Glycogen debranching enzyme
GD631_RS03825	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GD631_RS03830	COG3409	Peptidoglycan-binding domain 1 protein
GD631_RS03830	COG0793	Belongs to the peptidase S41A family
GD631_RS03850	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS03855	COG3250	beta-galactosidase activity
GD631_RS03860	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS03865	COG3292	Two component regulator propeller
GD631_RS03865	COG0745	RESPONSE REGULATOR receiver
GD631_RS03865	COG2205	protein histidine kinase activity
GD631_RS03870	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GD631_RS03885	COG4206	TonB-dependent receptor
GD631_RS03885	COG1629	transport
GD631_RS03890	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS03895	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS03915	COG1053	succinate dehydrogenase
GD631_RS03920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GD631_RS03990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GD631_RS03990	COG0758	DNA mediated transformation
GD631_RS04000	COG0826	peptidase U32
GD631_RS04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GD631_RS04065	COG0557	exoribonuclease II activity
GD631_RS04075	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS04100	COG4206	TonB-dependent receptor
GD631_RS04100	COG1629	transport
GD631_RS04110	COG0745	RESPONSE REGULATOR receiver
GD631_RS04110	COG2205	protein histidine kinase activity
GD631_RS04110	COG3292	Two component regulator propeller
GD631_RS04120	COG4206	TonB-dependent receptor
GD631_RS04120	COG1629	transport
GD631_RS04135	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS04140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GD631_RS04145	COG1917	Cupin 2, conserved barrel domain protein
GD631_RS04155	COG4124	Belongs to the glycosyl hydrolase 26 family
GD631_RS04175	COG0702	epimerase
GD631_RS04180	COG4771	TonB-dependent receptor
GD631_RS04185	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GD631_RS04205	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS04230	COG2205	protein histidine kinase activity
GD631_RS04230	COG0745	RESPONSE REGULATOR receiver
GD631_RS04230	COG3292	Two component regulator propeller
GD631_RS04230	COG0745	RESPONSE REGULATOR receiver
GD631_RS04230	COG3292	Two component regulator propeller
GD631_RS04230	COG2205	protein histidine kinase activity
GD631_RS04235	COG4771	TonB-dependent receptor
GD631_RS04250	COG0702	epimerase
GD631_RS04275	COG0702	epimerase
GD631_RS04280	COG4771	TonB-dependent receptor
GD631_RS04320	COG3119	arylsulfatase activity
GD631_RS04330	COG2814	Major facilitator Superfamily
GD631_RS04345	COG1629	transport
GD631_RS04345	COG4206	TonB-dependent receptor
GD631_RS04365	COG0012	GTP binding
GD631_RS04370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GD631_RS04375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GD631_RS04380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GD631_RS04405	COG4771	TonB-dependent receptor
GD631_RS04410	COG3537	Alpha-1,2-mannosidase
GD631_RS04420	COG1785	Belongs to the alkaline phosphatase family
GD631_RS04425	COG0697	spore germination
GD631_RS04435	COG3250	beta-galactosidase activity
GD631_RS04440	COG0495	leucyl-tRNA aminoacylation
GD631_RS04445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD631_RS04450	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GD631_RS04455	COG1360	Flagellar Motor Protein
GD631_RS04460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GD631_RS04470	COG3345	alpha-galactosidase
GD631_RS04490	COG3250	beta-galactosidase activity
GD631_RS04505	COG0561	phosphatase activity
GD631_RS04510	COG1629	transport
GD631_RS04515	COG3537	Alpha-1,2-mannosidase
GD631_RS04545	COG1629	transport
GD631_RS04545	COG4206	TonB-dependent receptor
GD631_RS04575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GD631_RS04575	COG0731	radical SAM domain protein
GD631_RS04600	COG0659	secondary active sulfate transmembrane transporter activity
GD631_RS04605	COG1592	Rubrerythrin
GD631_RS04655	COG0427	acetyl-CoA hydrolase
GD631_RS04665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GD631_RS04700	COG3023	N-Acetylmuramoyl-L-alanine amidase
GD631_RS04760	COG2177	Part of the ABC transporter FtsEX involved in
GD631_RS04770	COG1968	undecaprenyl-diphosphatase activity
GD631_RS04775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GD631_RS04780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GD631_RS04785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GD631_RS04795	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GD631_RS04825	COG0594	ribonuclease P activity
GD631_RS04830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GD631_RS04835	COG0084	hydrolase, TatD family'
GD631_RS04840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GD631_RS04850	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GD631_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS04895	COG0726	polysaccharide deacetylase
GD631_RS04915	COG4771	TonB-dependent receptor
GD631_RS04955	COG1121	(ABC) transporter
GD631_RS04965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GD631_RS04965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GD631_RS04970	COG1238	metal cluster binding
GD631_RS04985	COG0823	Involved in the tonB-independent uptake of proteins
GD631_RS04985	COG1506	peptidase
GD631_RS04995	COG0116	Belongs to the methyltransferase superfamily
GD631_RS04995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GD631_RS05000	COG1045	serine acetyltransferase
GD631_RS05010	COG3279	Response regulator of the LytR AlgR family
GD631_RS05020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GD631_RS05020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GD631_RS05035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GD631_RS05040	COG1694	Mazg nucleotide pyrophosphohydrolase
GD631_RS05045	COG1490	D-aminoacyl-tRNA deacylase activity
GD631_RS05050	COG0322	excinuclease ABC activity
GD631_RS05055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GD631_RS05060	COG0445	tRNA wobble uridine modification
GD631_RS05085	COG4771	TonB-dependent receptor
GD631_RS05130	COG4771	TonB-dependent receptor
GD631_RS05160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GD631_RS05165	COG2715	membrane protein required for spore maturation
GD631_RS05170	COG2255	four-way junction helicase activity
GD631_RS05190	COG3591	Belongs to the peptidase S1B family
GD631_RS05195	COG3408	Glycogen debranching enzyme
GD631_RS05200	COG0513	Belongs to the DEAD box helicase family
GD631_RS05220	COG3119	arylsulfatase activity
GD631_RS05225	COG3119	arylsulfatase activity
GD631_RS05230	COG3119	arylsulfatase activity
GD631_RS05240	COG0702	epimerase
GD631_RS05245	COG4771	TonB-dependent receptor
GD631_RS05250	COG3119	arylsulfatase activity
GD631_RS05260	COG3119	arylsulfatase activity
GD631_RS05270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD631_RS05285	COG0612	Peptidase, M16
GD631_RS05305	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GD631_RS05340	COG4771	TonB-dependent receptor
GD631_RS05345	COG0702	epimerase
GD631_RS05360	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS05375	COG0681	Belongs to the peptidase S26 family
GD631_RS05385	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GD631_RS05415	COG1215	transferase activity, transferring glycosyl groups
GD631_RS05435	COG5492	domain, Protein
GD631_RS05445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GD631_RS05455	COG0702	epimerase
GD631_RS05460	COG4771	TonB-dependent receptor
GD631_RS05465	COG3119	arylsulfatase activity
GD631_RS05470	COG0745	RESPONSE REGULATOR receiver
GD631_RS05470	COG2205	protein histidine kinase activity
GD631_RS05470	COG3292	Two component regulator propeller
GD631_RS05470	COG2205	protein histidine kinase activity
GD631_RS05470	COG3292	Two component regulator propeller
GD631_RS05470	COG0745	RESPONSE REGULATOR receiver
GD631_RS05485	COG1629	transport
GD631_RS05495	COG1629	transport
GD631_RS05515	COG0738	Major facilitator superfamily
GD631_RS05530	COG1940	carbohydrate kinase activity
GD631_RS05535	COG3250	beta-galactosidase activity
GD631_RS05540	COG3408	Glycogen debranching enzyme
GD631_RS05545	COG1609	Transcriptional regulator
GD631_RS05555	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GD631_RS05560	COG1538	Outer membrane efflux protein
GD631_RS05570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS05575	COG3250	beta-galactosidase activity
GD631_RS05620	COG1609	Transcriptional regulator
GD631_RS05635	COG0738	Major facilitator superfamily
GD631_RS05645	COG4771	TonB-dependent receptor
GD631_RS05670	COG0383	alpha-mannosidase activity
GD631_RS05680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS05685	COG3119	arylsulfatase activity
GD631_RS05690	COG5492	domain, Protein
GD631_RS05695	COG0215	cysteine-tRNA ligase activity
GD631_RS05700	COG0561	phosphatase activity
GD631_RS05720	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GD631_RS05725	COG0482	sulfurtransferase activity
GD631_RS05735	COG0205	6-phosphofructokinase activity
GD631_RS05740	COG0571	ribonuclease III activity
GD631_RS05745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GD631_RS05750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GD631_RS05755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GD631_RS05760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GD631_RS05795	COG0438	transferase activity, transferring glycosyl groups
GD631_RS05800	COG3475	LICD family
GD631_RS05805	COG4750	Nucleotidyl transferase
GD631_RS05820	COG1216	Glycosyl transferase, family 2
GD631_RS05825	COG3754	Rhamnan synthesis protein F
GD631_RS05840	COG1215	transferase activity, transferring glycosyl groups
GD631_RS05845	COG0438	transferase activity, transferring glycosyl groups
GD631_RS05850	COG1216	Glycosyl transferase, family 2
GD631_RS05865	COG2076	Multidrug Resistance protein
GD631_RS05875	COG0463	Glycosyl transferase, family 2
GD631_RS05885	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GD631_RS05920	COG1132	(ABC) transporter
GD631_RS05930	COG0463	Glycosyl transferase, family 2
GD631_RS05940	COG1368	sulfuric ester hydrolase activity
GD631_RS05950	COG3341	Caulimovirus viroplasmin
GD631_RS05950	COG0328	RNA-DNA hybrid ribonuclease activity
GD631_RS05960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GD631_RS05970	COG0326	Molecular chaperone. Has ATPase activity
GD631_RS05980	COG1166	arginine decarboxylase activity
GD631_RS05985	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GD631_RS05990	COG1595	DNA-templated transcription, initiation
GD631_RS06015	COG0779	Required for maturation of 30S ribosomal subunits
GD631_RS06020	COG0195	Participates in both transcription termination and antitermination
GD631_RS06025	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GD631_RS06035	COG0719	Fe-S assembly protein
GD631_RS06040	COG0396	ATPase activity
GD631_RS06045	COG0719	Fe-S assembly protein
GD631_RS06050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GD631_RS06060	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GD631_RS06065	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GD631_RS06080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GD631_RS06095	COG0187	DNA topoisomerase II activity
GD631_RS06100	COG0268	Binds directly to 16S ribosomal RNA
GD631_RS06110	COG1381	Involved in DNA repair and RecF pathway recombination
GD631_RS06165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GD631_RS06180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GD631_RS06185	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GD631_RS06190	COG0772	Belongs to the SEDS family
GD631_RS06195	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GD631_RS06200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GD631_RS06205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GD631_RS06220	COG0275	rRNA processing
GD631_RS06225	COG2001	Belongs to the MraZ family
GD631_RS06230	COG1595	DNA-templated transcription, initiation
GD631_RS06245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GD631_RS06250	COG0756	dUTP diphosphatase activity
GD631_RS06265	COG4942	peptidase
GD631_RS06270	COG0745	RESPONSE REGULATOR receiver
GD631_RS06270	COG2205	protein histidine kinase activity
GD631_RS06270	COG3292	Two component regulator propeller
GD631_RS06285	COG3119	arylsulfatase activity
GD631_RS06315	COG1629	transport
GD631_RS06320	COG0561	phosphatase activity
GD631_RS06355	COG3537	Alpha-1,2-mannosidase
GD631_RS06365	COG2017	converts alpha-aldose to the beta-anomer
GD631_RS06515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD631_RS06520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GD631_RS06530	COG4206	TonB-dependent receptor
GD631_RS06530	COG1629	transport
GD631_RS06540	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS06540	COG3291	Pkd domain containing protein
GD631_RS06550	COG3250	beta-galactosidase activity
GD631_RS06560	COG1022	Amp-dependent synthetase and ligase
GD631_RS06565	COG0612	Peptidase, M16
GD631_RS06580	COG2954	triphosphatase activity
GD631_RS06615	COG1864	DNA RNA non-specific endonuclease
GD631_RS06615	COG3591	Belongs to the peptidase S1B family
GD631_RS06645	COG0561	phosphatase activity
GD631_RS06650	COG4771	TonB-dependent receptor
GD631_RS06660	COG3537	Alpha-1,2-mannosidase
GD631_RS06680	COG0702	epimerase
GD631_RS06685	COG1629	transport
GD631_RS06685	COG4206	TonB-dependent receptor
GD631_RS06690	COG3250	beta-galactosidase activity
GD631_RS06695	COG0745	RESPONSE REGULATOR receiver
GD631_RS06695	COG3292	Two component regulator propeller
GD631_RS06695	COG2205	protein histidine kinase activity
GD631_RS06720	COG0673	inositol 2-dehydrogenase activity
GD631_RS06725	COG0673	inositol 2-dehydrogenase activity
GD631_RS06750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GD631_RS06765	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS06785	COG1629	transport
GD631_RS06790	COG1609	Transcriptional regulator
GD631_RS06790	COG2207	Transcriptional regulator
GD631_RS06800	COG0423	glycine-tRNA ligase activity
GD631_RS06810	COG1609	Transcriptional regulator
GD631_RS06825	COG0738	Major facilitator superfamily
GD631_RS06830	COG1063	alcohol dehydrogenase
GD631_RS06840	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS06845	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS06850	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS06860	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS06865	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS06870	COG4771	TonB-dependent receptor
GD631_RS06885	COG0702	epimerase
GD631_RS06905	COG2382	esterase
GD631_RS06910	COG3507	Belongs to the glycosyl hydrolase 43 family
GD631_RS06915	COG2205	protein histidine kinase activity
GD631_RS06915	COG0745	RESPONSE REGULATOR receiver
GD631_RS06915	COG3292	Two component regulator propeller
GD631_RS06930	COG0745	RESPONSE REGULATOR receiver
GD631_RS06930	COG0745	RESPONSE REGULATOR receiver
GD631_RS06930	COG2205	protein histidine kinase activity
GD631_RS06930	COG3292	Two component regulator propeller
GD631_RS06930	COG3292	Two component regulator propeller
GD631_RS06930	COG2205	protein histidine kinase activity
GD631_RS06940	COG1629	transport
GD631_RS06945	COG0561	phosphatase activity
GD631_RS06975	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GD631_RS06985	COG2211	Major facilitator Superfamily
GD631_RS06995	COG1216	Glycosyl transferase, family 2
GD631_RS06995	COG0463	Glycosyl transferase, family 2
GD631_RS07000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD631_RS07055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GD631_RS07060	COG0475	glutathione-regulated potassium exporter activity
GD631_RS07060	COG0589	response to stress
GD631_RS07065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GD631_RS07070	COG1136	(ABC) transporter
GD631_RS07080	COG0733	neurotransmitter:sodium symporter activity
GD631_RS07090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GD631_RS07095	COG0784	Response regulator, receiver
GD631_RS07095	COG5002	protein histidine kinase activity
GD631_RS07100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GD631_RS07105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GD631_RS07120	COG1346	cytolysis
GD631_RS07125	COG1380	Effector of murein hydrolase LrgA
GD631_RS07130	COG0280	phosphate acetyltransferase
GD631_RS07135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GD631_RS07180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD631_RS07185	COG1120	ATPase activity
GD631_RS07210	COG1192	Involved in chromosome partitioning
GD631_RS07220	COG1629	transport
GD631_RS07285	COG4974	Belongs to the 'phage' integrase family
GD631_RS07290	COG4974	Belongs to the 'phage' integrase family
GD631_RS07300	COG1349	DNA-binding transcription factor activity
GD631_RS07305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GD631_RS07315	COG0371	Dehydrogenase
GD631_RS07320	COG2271	Major facilitator Superfamily
GD631_RS07335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS07365	COG1629	transport
GD631_RS07390	COG0463	Glycosyl transferase, family 2
GD631_RS07390	COG1216	Glycosyl transferase, family 2
GD631_RS07395	COG2003	Belongs to the UPF0758 family
GD631_RS07420	COG4206	TonB-dependent receptor
GD631_RS07420	COG1629	transport
GD631_RS07425	COG1082	Xylose isomerase domain protein TIM barrel
GD631_RS07430	COG0366	Alpha amylase catalytic
GD631_RS07440	COG1785	Belongs to the alkaline phosphatase family
GD631_RS07445	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GD631_RS07450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GD631_RS07455	COG0515	serine threonine protein kinase
GD631_RS07455	COG2815	serine threonine protein kinase
GD631_RS07460	COG0564	pseudouridine synthase activity
GD631_RS07485	COG0671	phosphoesterase, PA-phosphatase related
GD631_RS07490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GD631_RS07495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GD631_RS07500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GD631_RS07505	COG0436	Aminotransferase
GD631_RS07515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GD631_RS07530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GD631_RS07535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GD631_RS07545	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD631_RS07545	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD631_RS07550	COG2890	protein-(glutamine-N5) methyltransferase activity
GD631_RS07560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GD631_RS07570	COG0165	Argininosuccinate lyase
GD631_RS07595	COG1629	transport
GD631_RS07595	COG4206	TonB-dependent receptor
GD631_RS07615	COG3344	reverse transcriptase
GD631_RS07655	COG1629	transport
GD631_RS07670	COG4677	pectinesterase activity
GD631_RS07675	COG2205	protein histidine kinase activity
GD631_RS07675	COG3292	Two component regulator propeller
GD631_RS07675	COG0745	RESPONSE REGULATOR receiver
GD631_RS07685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GD631_RS07690	COG1396	sequence-specific DNA binding
GD631_RS07690	COG1917	Cupin 2, conserved barrel domain protein
GD631_RS07700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GD631_RS07705	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GD631_RS07710	COG0137	argininosuccinate synthase activity
GD631_RS07720	COG1438	arginine binding
GD631_RS07725	COG1070	Carbohydrate kinase
GD631_RS07730	COG4806	L-rhamnose isomerase
GD631_RS07740	COG0235	Class ii aldolase
GD631_RS07745	COG1454	alcohol dehydrogenase
GD631_RS07755	COG2205	protein histidine kinase activity
GD631_RS07755	COG0745	RESPONSE REGULATOR receiver
GD631_RS07755	COG3292	Two component regulator propeller
GD631_RS07755	COG2205	protein histidine kinase activity
GD631_RS07755	COG3292	Two component regulator propeller
GD631_RS07755	COG0745	RESPONSE REGULATOR receiver
GD631_RS07760	COG4771	TonB-dependent receptor
GD631_RS07765	COG0702	epimerase
GD631_RS07795	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS07800	COG3250	beta-galactosidase activity
GD631_RS07835	COG0564	pseudouridine synthase activity
GD631_RS07865	COG4771	TonB-dependent receptor
GD631_RS07875	COG1595	DNA-templated transcription, initiation
GD631_RS07890	COG2204	response regulator
GD631_RS07895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GD631_RS07895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GD631_RS07900	COG0612	Peptidase, M16
GD631_RS07905	COG0534	Mate efflux family protein
GD631_RS07930	COG0488	(ABC) transporter
GD631_RS07935	COG3590	peptidase
GD631_RS07940	COG0138	bifunctional purine biosynthesis protein purh
GD631_RS07965	COG0772	Belongs to the SEDS family
GD631_RS07975	COG1774	PSP1 C-terminal conserved region
GD631_RS07980	COG0470	DNA polymerase III
GD631_RS07985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GD631_RS07990	COG2193	ferroxidase activity
GD631_RS08030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GD631_RS08035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GD631_RS08040	COG1160	GTP binding
GD631_RS08050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GD631_RS08055	COG1127	ABC transporter
GD631_RS08060	COG0724	RNA recognition motif
GD631_RS08065	COG0544	peptidyl-prolyl cis-trans isomerase activity
GD631_RS08070	COG0740	serine-type endopeptidase activity
GD631_RS08075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GD631_RS08080	COG0514	ATP-dependent DNA helicase (RecQ)
GD631_RS08085	COG0516	GMP reductase activity
GD631_RS08085	COG0517	IMP dehydrogenase activity
GD631_RS08100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GD631_RS08115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GD631_RS08130	COG4771	TonB-dependent receptor
GD631_RS08150	COG3537	Alpha-1,2-mannosidase
GD631_RS08215	COG3022	response to hydroperoxide
GD631_RS08220	COG0110	maltose O-acetyltransferase activity
GD631_RS08240	COG1187	pseudouridine synthase activity
GD631_RS08245	COG0017	Asparaginyl-tRNA synthetase
GD631_RS08255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS08265	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GD631_RS08270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GD631_RS08275	COG0052	Belongs to the universal ribosomal protein uS2 family
GD631_RS08280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GD631_RS08295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GD631_RS08300	COG0179	Fumarylacetoacetate (FAA) hydrolase
GD631_RS08305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GD631_RS08320	COG0482	sulfurtransferase activity
GD631_RS08330	COG1570	exodeoxyribonuclease VII activity
GD631_RS08340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD631_RS08350	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GD631_RS08355	COG0489	protein tyrosine kinase activity
GD631_RS08360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD631_RS08400	COG0039	L-malate dehydrogenase activity
GD631_RS08410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GD631_RS08415	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GD631_RS08420	COG0811	peptide transport
GD631_RS08425	COG0848	biopolymer transport protein
GD631_RS08440	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GD631_RS08445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GD631_RS08450	COG0105	UTP biosynthetic process
GD631_RS08455	COG0739	heme binding
GD631_RS08470	COG0149	triose-phosphate isomerase activity
GD631_RS08480	COG0302	gtp cyclohydrolase
GD631_RS08485	COG0358	DNA primase activity
GD631_RS08495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GD631_RS08515	COG0514	ATP-dependent DNA helicase (RecQ)
GD631_RS08520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GD631_RS08520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GD631_RS08535	COG1629	transport
GD631_RS08595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GD631_RS08610	COG0726	polysaccharide deacetylase
GD631_RS08620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GD631_RS08625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GD631_RS08630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GD631_RS08640	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GD631_RS08655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GD631_RS08660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GD631_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS08680	COG4771	TonB-dependent receptor
GD631_RS08690	COG0009	L-threonylcarbamoyladenylate synthase
GD631_RS08700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GD631_RS08705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GD631_RS08710	COG2333	competence protein COMEC
GD631_RS08710	COG0658	competence protein
GD631_RS08715	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GD631_RS08725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GD631_RS08745	COG4771	TonB-dependent receptor
GD631_RS08750	COG0702	epimerase
GD631_RS08775	COG3537	Alpha-1,2-mannosidase
GD631_RS08785	COG4771	TonB-dependent receptor
GD631_RS08795	COG3537	Alpha-1,2-mannosidase
GD631_RS08800	COG3537	Alpha-1,2-mannosidase
GD631_RS08810	COG3537	Alpha-1,2-mannosidase
GD631_RS08815	COG4948	Mandelate Racemase Muconate Lactonizing
GD631_RS08820	COG3279	Response regulator of the LytR AlgR family
GD631_RS08825	COG3275	phosphorelay sensor kinase activity
GD631_RS08840	COG0386	Belongs to the glutathione peroxidase family
GD631_RS08850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GD631_RS08865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GD631_RS08880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GD631_RS08885	COG0742	ribosomal rna small subunit methyltransferase
GD631_RS08900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GD631_RS08930	COG1629	transport
GD631_RS08930	COG4206	TonB-dependent receptor
GD631_RS08940	COG3537	Alpha-1,2-mannosidase
GD631_RS08945	COG3537	Alpha-1,2-mannosidase
GD631_RS08965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GD631_RS08970	COG0739	heme binding
GD631_RS08980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GD631_RS08985	COG0741	lytic transglycosylase activity
GD631_RS08985	COG1388	LysM domain
GD631_RS08995	COG1475	DNA binding
GD631_RS09000	COG1192	Involved in chromosome partitioning
GD631_RS09005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GD631_RS09010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GD631_RS09020	COG4589	Belongs to the CDS family
GD631_RS09025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GD631_RS09040	COG1196	nuclear chromosome segregation
GD631_RS09045	COG2239	Acts as a magnesium transporter
GD631_RS09050	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GD631_RS09060	COG2195	Cleaves the N-terminal amino acid of tripeptides
GD631_RS09095	COG0668	transmembrane transport
GD631_RS09100	COG0662	Cupin 2, conserved barrel domain protein
GD631_RS09100	COG2207	Transcriptional regulator
GD631_RS09130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GD631_RS09135	COG0713	ATP synthesis coupled electron transport
GD631_RS09150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GD631_RS09155	COG0649	NAD binding
GD631_RS09155	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GD631_RS09160	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GD631_RS09165	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GD631_RS09200	COG3250	beta-galactosidase activity
GD631_RS09210	COG3250	beta-galactosidase activity
GD631_RS09230	COG1629	transport
GD631_RS09235	COG0702	epimerase
GD631_RS09240	COG4771	TonB-dependent receptor
GD631_RS09275	COG3537	Alpha-1,2-mannosidase
GD631_RS09290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GD631_RS09295	COG0569	domain protein
GD631_RS09300	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GD631_RS09310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GD631_RS09315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GD631_RS09320	COG0805	protein transport
GD631_RS09330	COG2271	Major facilitator Superfamily
GD631_RS09335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GD631_RS09340	COG3775	system Galactitol-specific IIC component
GD631_RS09355	COG2755	lipolytic protein G-D-S-L family
GD631_RS09360	COG3292	Two component regulator propeller
GD631_RS09360	COG2205	protein histidine kinase activity
GD631_RS09360	COG0745	RESPONSE REGULATOR receiver
GD631_RS09370	COG0702	epimerase
GD631_RS09375	COG4206	TonB-dependent receptor
GD631_RS09375	COG1629	transport
GD631_RS09395	COG3279	Response regulator of the LytR AlgR family
GD631_RS09415	COG1629	transport
GD631_RS09420	COG0702	epimerase
GD631_RS09435	COG3344	reverse transcriptase
GD631_RS09445	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS09450	COG2205	protein histidine kinase activity
GD631_RS09450	COG0745	RESPONSE REGULATOR receiver
GD631_RS09450	COG3292	Two component regulator propeller
GD631_RS09455	COG1242	4 iron, 4 sulfur cluster binding
GD631_RS09465	COG0363	glucosamine-6-phosphate deaminase activity
GD631_RS09470	COG0009	L-threonylcarbamoyladenylate synthase
GD631_RS09480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GD631_RS09485	COG0561	phosphatase activity
GD631_RS09490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GD631_RS09515	COG2755	lipolytic protein G-D-S-L family
GD631_RS09555	COG2755	lipolytic protein G-D-S-L family
GD631_RS09565	COG3401	FG-GAP repeat protein
GD631_RS09580	COG3292	Two component regulator propeller
GD631_RS09580	COG3292	Two component regulator propeller
GD631_RS09580	COG0745	RESPONSE REGULATOR receiver
GD631_RS09580	COG2205	protein histidine kinase activity
GD631_RS09580	COG2205	protein histidine kinase activity
GD631_RS09580	COG0745	RESPONSE REGULATOR receiver
GD631_RS09585	COG3250	beta-galactosidase activity
GD631_RS09590	COG3401	FG-GAP repeat protein
GD631_RS09600	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS09615	COG4771	TonB-dependent receptor
GD631_RS09620	COG0702	epimerase
GD631_RS09635	COG4771	TonB-dependent receptor
GD631_RS09705	COG2205	protein histidine kinase activity
GD631_RS09705	COG3292	Two component regulator propeller
GD631_RS09705	COG2205	protein histidine kinase activity
GD631_RS09705	COG0745	RESPONSE REGULATOR receiver
GD631_RS09705	COG3292	Two component regulator propeller
GD631_RS09705	COG0745	RESPONSE REGULATOR receiver
GD631_RS09745	COG3279	Response regulator of the LytR AlgR family
GD631_RS09765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GD631_RS09775	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GD631_RS09785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GD631_RS09790	COG1506	peptidase
GD631_RS09790	COG0823	Involved in the tonB-independent uptake of proteins
GD631_RS09805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GD631_RS09820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GD631_RS09820	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GD631_RS09825	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GD631_RS09830	COG1078	dGTPase activity
GD631_RS09835	COG0284	orotidine-5'-phosphate decarboxylase activity
GD631_RS09840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GD631_RS09845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GD631_RS09850	COG1704	LemA family
GD631_RS09865	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GD631_RS09870	COG2226	methyltransferase
GD631_RS09875	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GD631_RS09880	COG1702	phosphate starvation-inducible protein PhoH
GD631_RS09905	COG2268	Band 7 protein
GD631_RS09955	COG3292	Two component regulator propeller
GD631_RS09955	COG0745	RESPONSE REGULATOR receiver
GD631_RS09955	COG2205	protein histidine kinase activity
GD631_RS09960	COG0101	tRNA pseudouridine synthase activity
GD631_RS09985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD631_RS09990	COG0673	inositol 2-dehydrogenase activity
GD631_RS10005	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GD631_RS10015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GD631_RS10030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GD631_RS10035	COG0793	Belongs to the peptidase S41A family
GD631_RS10040	COG2131	deaminase
GD631_RS10050	COG0339	signal peptide processing
GD631_RS10055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GD631_RS10060	COG1970	mechanosensitive ion channel activity
GD631_RS10065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GD631_RS10065	COG0519	Catalyzes the synthesis of GMP from XMP
GD631_RS10090	COG0297	glycogen (starch) synthase activity
GD631_RS10105	COG0297	glycogen (starch) synthase activity
GD631_RS10110	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GD631_RS10115	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GD631_RS10120	COG0543	2 iron, 2 sulfur cluster binding
GD631_RS10125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GD631_RS10130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GD631_RS10135	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GD631_RS10150	COG0791	NLP P60 protein
GD631_RS10165	COG0612	Peptidase, M16
GD631_RS10170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GD631_RS10175	COG1597	lipid kinase activity
GD631_RS10180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GD631_RS10195	COG3250	beta-galactosidase activity
GD631_RS10200	COG3250	beta-galactosidase activity
GD631_RS10205	COG1629	transport
GD631_RS10205	COG4206	TonB-dependent receptor
GD631_RS10250	COG1136	(ABC) transporter
GD631_RS10270	COG2211	Major facilitator Superfamily
GD631_RS10275	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GD631_RS10290	COG1674	ftsk spoiiie
GD631_RS10300	COG0492	ferredoxin-NADP+ reductase activity
GD631_RS10340	COG4206	TonB-dependent receptor
GD631_RS10340	COG1629	transport
GD631_RS10375	COG4206	TonB-dependent receptor
GD631_RS10375	COG1629	transport
GD631_RS10385	COG3537	Alpha-1,2-mannosidase
GD631_RS10395	COG1785	Belongs to the alkaline phosphatase family
GD631_RS10410	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS10415	COG2133	pyrroloquinoline quinone binding
GD631_RS10415	COG5183	chlorophyll binding
GD631_RS10420	COG2207	Transcriptional regulator
GD631_RS10420	COG1609	Transcriptional regulator
GD631_RS10445	COG1234	tRNA 3'-trailer cleavage
GD631_RS10450	COG2989	Protein conserved in bacteria
GD631_RS10470	COG3956	TIGRFAM MazG family protein
GD631_RS10490	COG0525	valine-tRNA ligase activity
GD631_RS10510	COG4206	TonB-dependent receptor
GD631_RS10510	COG1629	transport
GD631_RS10515	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GD631_RS10540	COG0653	protein targeting
GD631_RS10545	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
GD631_RS10555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GD631_RS10575	COG1253	flavin adenine dinucleotide binding
GD631_RS10590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GD631_RS10600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GD631_RS10605	COG2204	response regulator
GD631_RS10645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GD631_RS10645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GD631_RS10660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GD631_RS10665	COG0563	adenylate kinase activity
GD631_RS10670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GD631_RS10675	COG1496	oxidoreductase activity
GD631_RS10690	COG2706	6-phosphogluconolactonase activity
GD631_RS10745	COG2048	Heterodisulfide reductase, subunit B
GD631_RS10785	COG3142	Participates in the control of copper homeostasis
GD631_RS10790	COG1418	mRNA catabolic process
GD631_RS10835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD631_RS10835	COG1333	cytochrome c biogenesis protein
GD631_RS10920	COG4771	TonB-dependent receptor
GD631_RS10955	COG0246	Mannitol dehydrogenase
GD631_RS10965	COG1063	alcohol dehydrogenase
GD631_RS10980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GD631_RS10985	COG2832	Protein of unknown function (DUF454)
GD631_RS10995	COG0602	queuosine metabolic process
GD631_RS11000	COG0247	lactate metabolic process
GD631_RS11005	COG1139	Iron-sulfur cluster binding protein
GD631_RS11015	COG0351	phosphomethylpyrimidine kinase
GD631_RS11040	COG4589	Belongs to the CDS family
GD631_RS11050	COG2304	oxidoreductase activity
GD631_RS11060	COG1393	Belongs to the ArsC family
GD631_RS11070	COG4771	TonB-dependent receptor
GD631_RS11085	COG2233	PERMEase
GD631_RS11090	COG1509	lysine 2,3-aminomutase activity
GD631_RS11120	COG1285	pathogenesis
GD631_RS11130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GD631_RS11135	COG1388	LysM domain
GD631_RS11135	COG0741	lytic transglycosylase activity
GD631_RS11150	COG2205	protein histidine kinase activity
GD631_RS11150	COG2198	Histidine kinase
GD631_RS11150	COG0784	Response regulator, receiver
GD631_RS11175	COG0534	Mate efflux family protein
GD631_RS11180	COG0564	pseudouridine synthase activity
GD631_RS11205	COG0346	lactoylglutathione lyase activity
GD631_RS11215	COG0653	protein targeting
GD631_RS11240	COG1401	restriction endodeoxyribonuclease activity
GD631_RS11245	COG4268	DNA restriction-modification system
GD631_RS11255	COG1063	alcohol dehydrogenase
GD631_RS11270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GD631_RS11275	COG0784	Response regulator, receiver
GD631_RS11275	COG5002	protein histidine kinase activity
GD631_RS11280	COG0702	epimerase
GD631_RS11290	COG4864	UPF0365 protein
GD631_RS11305	COG0037	tRNA processing
GD631_RS11345	COG2003	Belongs to the UPF0758 family
GD631_RS11385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GD631_RS11415	COG1477	protein flavinylation
GD631_RS11420	COG1971	Probably functions as a manganese efflux pump
GD631_RS11435	COG0463	Glycosyl transferase, family 2
GD631_RS11460	COG0148	phosphopyruvate hydratase activity
GD631_RS11470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GD631_RS11485	COG1082	Xylose isomerase domain protein TIM barrel
GD631_RS11490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GD631_RS11495	COG2195	Cleaves the N-terminal amino acid of tripeptides
GD631_RS11500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GD631_RS11505	COG4651	solute:proton antiporter activity
GD631_RS11505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GD631_RS11515	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GD631_RS11520	COG0193	aminoacyl-tRNA hydrolase activity
GD631_RS11525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GD631_RS11535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GD631_RS11550	COG0237	dephospho-CoA kinase activity
GD631_RS11565	COG0542	response to heat
GD631_RS11575	COG0583	DNA-binding transcription factor activity
GD631_RS11580	COG3304	Inner membrane component domain
GD631_RS11585	COG2855	membrane
GD631_RS11590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GD631_RS11595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GD631_RS11615	COG0443	Heat shock 70 kDa protein
GD631_RS11625	COG4651	solute:proton antiporter activity
GD631_RS11625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GD631_RS11630	COG0306	phosphate transporter
GD631_RS11640	COG0586	Pfam SNARE associated Golgi protein
GD631_RS11685	COG0038	chloride channel
GD631_RS11690	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GD631_RS11705	COG1940	carbohydrate kinase activity
GD631_RS11715	COG3119	arylsulfatase activity
GD631_RS11725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS11730	COG0702	epimerase
GD631_RS11735	COG4771	TonB-dependent receptor
GD631_RS11745	COG5434	Belongs to the glycosyl hydrolase 28 family
GD631_RS11750	COG3292	Two component regulator propeller
GD631_RS11750	COG2205	protein histidine kinase activity
GD631_RS11750	COG0745	RESPONSE REGULATOR receiver
GD631_RS11755	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GD631_RS11760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GD631_RS11795	COG4974	Belongs to the 'phage' integrase family
GD631_RS11820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GD631_RS11825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GD631_RS11825	COG0517	IMP dehydrogenase activity
GD631_RS11830	COG1083	cytidylyl-transferase
GD631_RS11835	COG2244	polysaccharide biosynthetic process
GD631_RS11850	COG1216	Glycosyl transferase, family 2
GD631_RS11855	COG1442	glycosyl transferase family 8
GD631_RS11855	COG1216	Glycosyl transferase, family 2
GD631_RS11875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GD631_RS11895	COG1760	l-serine dehydratase
GD631_RS11900	COG0598	Magnesium transport protein CorA
GD631_RS11905	COG1193	negative regulation of DNA recombination
GD631_RS11915	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GD631_RS11935	COG0561	phosphatase activity
GD631_RS11940	COG1169	isochorismate synthase
GD631_RS11945	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GD631_RS11950	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GD631_RS11955	COG4948	Mandelate Racemase Muconate Lactonizing
GD631_RS11960	COG0318	PFAM AMP-dependent synthetase and ligase
GD631_RS11975	COG1191	sigma factor activity
GD631_RS11990	COG1629	transport
GD631_RS11990	COG4206	TonB-dependent receptor
GD631_RS12010	COG1595	DNA-templated transcription, initiation
GD631_RS12020	COG1629	transport
GD631_RS12020	COG4206	TonB-dependent receptor
GD631_RS12045	COG3119	arylsulfatase activity
GD631_RS12050	COG0783	Belongs to the Dps family
GD631_RS12080	COG1595	DNA-templated transcription, initiation
GD631_RS12095	COG4771	TonB-dependent receptor
GD631_RS12105	COG0584	glycerophosphoryl diester phosphodiesterase
GD631_RS12110	COG0584	glycerophosphoryl diester phosphodiesterase
GD631_RS12135	COG4771	TonB-dependent receptor
GD631_RS12140	COG0702	epimerase
GD631_RS12150	COG0584	glycerophosphoryl diester phosphodiesterase
GD631_RS12155	COG2271	Major facilitator Superfamily
GD631_RS12195	COG3023	N-Acetylmuramoyl-L-alanine amidase
GD631_RS12200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GD631_RS12205	COG1882	Formate acetyltransferase
GD631_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS12270	COG0662	Cupin 2, conserved barrel domain protein
GD631_RS12270	COG2207	Transcriptional regulator
GD631_RS12295	COG1253	flavin adenine dinucleotide binding
GD631_RS12300	COG0501	Belongs to the peptidase M48B family
GD631_RS12330	COG0482	sulfurtransferase activity
GD631_RS12345	COG2197	response regulator
GD631_RS12355	COG1757	Na H antiporter
GD631_RS12365	COG2814	Major facilitator Superfamily
GD631_RS12370	COG4953	penicillin-binding protein 1C
GD631_RS12375	COG2373	Large extracellular alpha-helical protein
GD631_RS12380	COG0545	Peptidyl-prolyl cis-trans isomerase
GD631_RS12420	COG4771	TonB-dependent receptor
GD631_RS12450	COG1629	transport
GD631_RS12455	COG0702	epimerase
GD631_RS12475	COG3250	beta-galactosidase activity
GD631_RS12495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GD631_RS12500	COG1410	methionine synthase
GD631_RS12500	COG0646	methionine synthase
GD631_RS12505	COG0778	Nitroreductase
GD631_RS12510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD631_RS12515	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GD631_RS12520	COG0572	uridine kinase
GD631_RS12530	COG4232	protein-disulfide reductase activity
GD631_RS12545	COG4771	TonB-dependent receptor
GD631_RS12550	COG0702	epimerase
GD631_RS12575	COG2271	Major facilitator Superfamily
GD631_RS12595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GD631_RS12600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GD631_RS12605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GD631_RS12610	COG0131	Imidazoleglycerol-phosphate dehydratase
GD631_RS12620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GD631_RS12620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GD631_RS12655	COG1404	Belongs to the peptidase S8 family
GD631_RS12675	COG1592	Rubrerythrin
GD631_RS12675	COG1773	rubredoxin
GD631_RS12690	COG3118	belongs to the thioredoxin family
GD631_RS12700	COG3591	Belongs to the peptidase S1B family
GD631_RS12705	COG3591	Belongs to the peptidase S1B family
GD631_RS12710	COG0641	radical SAM
GD631_RS12735	COG0420	3'-5' exonuclease activity
GD631_RS12755	COG0646	methionine synthase
GD631_RS12755	COG1410	methionine synthase
GD631_RS12765	COG0463	Glycosyl transferase, family 2
GD631_RS12770	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GD631_RS12775	COG1032	radical SAM domain protein
GD631_RS12795	COG0363	glucosamine-6-phosphate deaminase activity
GD631_RS12800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GD631_RS12815	COG1752	Esterase of the alpha-beta hydrolase superfamily
GD631_RS12855	COG0508	dehydrogenase complex catalyzes the overall conversion of
GD631_RS12860	COG0022	dehydrogenase e1 component
GD631_RS12870	COG2264	protein methyltransferase activity
GD631_RS12890	COG0590	tRNA wobble adenosine to inosine editing
GD631_RS12895	COG0673	inositol 2-dehydrogenase activity
GD631_RS12910	COG0702	epimerase
GD631_RS12915	COG1629	transport
GD631_RS12930	COG3250	beta-galactosidase activity
GD631_RS12935	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS12940	COG3292	Two component regulator propeller
GD631_RS12940	COG2205	protein histidine kinase activity
GD631_RS12940	COG0745	RESPONSE REGULATOR receiver
GD631_RS12945	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GD631_RS12995	COG4771	TonB-dependent receptor
GD631_RS13010	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS13035	COG1501	Belongs to the glycosyl hydrolase 31 family
GD631_RS13040	COG5012	cobalamin binding
GD631_RS13055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GD631_RS13060	COG0698	ribose 5-phosphate isomerase
GD631_RS13080	COG1070	Carbohydrate kinase
GD631_RS13085	COG2160	L-arabinose isomerase activity
GD631_RS13095	COG2816	NAD+ diphosphatase activity
GD631_RS13110	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GD631_RS13125	COG1482	cell wall glycoprotein biosynthetic process
GD631_RS13130	COG4974	Belongs to the 'phage' integrase family
GD631_RS13190	COG0489	protein tyrosine kinase activity
GD631_RS13215	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS13220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GD631_RS13225	COG0318	PFAM AMP-dependent synthetase and ligase
GD631_RS13230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GD631_RS13255	COG2244	polysaccharide biosynthetic process
GD631_RS13265	COG1215	transferase activity, transferring glycosyl groups
GD631_RS13290	COG3594	Acyltransferase
GD631_RS13300	COG1216	Glycosyl transferase, family 2
GD631_RS13300	COG1442	glycosyl transferase family 8
GD631_RS13310	COG0438	transferase activity, transferring glycosyl groups
GD631_RS13320	COG0110	maltose O-acetyltransferase activity
GD631_RS13340	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GD631_RS13385	COG4221	oxidoreductase activity
GD631_RS13395	COG1218	3'(2'),5'-bisphosphate nucleotidase
GD631_RS13400	COG0471	metal ion transport
GD631_RS13400	COG3273	potassium ion transport
GD631_RS13405	COG0529	Catalyzes the synthesis of activated sulfate
GD631_RS13410	COG0175	sulfate reduction
GD631_RS13415	COG2895	sulfate adenylyltransferase (ATP) activity
GD631_RS13435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GD631_RS13440	COG0242	peptide deformylase activity
GD631_RS13450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GD631_RS13455	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GD631_RS13460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GD631_RS13465	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GD631_RS13475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GD631_RS13480	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GD631_RS13485	COG0674	pyruvate-flavodoxin oxidoreductase activity
GD631_RS13485	COG1013	pyruvate-flavodoxin oxidoreductase activity
GD631_RS13485	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GD631_RS13485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GD631_RS13495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GD631_RS13505	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GD631_RS13520	COG1940	carbohydrate kinase activity
GD631_RS13535	COG2814	Major facilitator Superfamily
GD631_RS13560	COG1629	transport
GD631_RS13560	COG4206	TonB-dependent receptor
GD631_RS13565	COG0702	epimerase
GD631_RS13615	COG4771	TonB-dependent receptor
GD631_RS13645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS13650	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS13655	COG4771	TonB-dependent receptor
GD631_RS13660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GD631_RS13665	COG4335	DNA alkylation repair
GD631_RS13670	COG0484	heat shock protein binding
GD631_RS13675	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GD631_RS13680	COG0488	(ABC) transporter
GD631_RS13705	COG3023	N-Acetylmuramoyl-L-alanine amidase
GD631_RS13725	COG2183	response to ionizing radiation
GD631_RS13730	COG2205	protein histidine kinase activity
GD631_RS13730	COG2202	Pas domain
GD631_RS13735	COG0737	Belongs to the 5'-nucleotidase family
GD631_RS14000	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GD631_RS14015	COG0490	domain, Protein
GD631_RS14015	COG2985	domain, Protein
GD631_RS14020	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GD631_RS14030	COG1022	Amp-dependent synthetase and ligase
GD631_RS14035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD631_RS14040	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GD631_RS14045	COG1301	dicarboxylic acid transport
GD631_RS14050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GD631_RS14055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GD631_RS14060	COG0363	glucosamine-6-phosphate deaminase activity
GD631_RS14065	COG2837	iron assimilation
GD631_RS14075	COG3279	Response regulator of the LytR AlgR family
GD631_RS14085	COG0577	efflux transmembrane transporter activity
GD631_RS14085	COG1136	(ABC) transporter
GD631_RS14090	COG1136	(ABC) transporter
GD631_RS14110	COG1271	oxidase subunit
GD631_RS14120	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GD631_RS14125	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GD631_RS14150	COG0501	Belongs to the peptidase M48B family
GD631_RS14155	COG1704	LemA family
GD631_RS14165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD631_RS14170	COG2885	chlorophyll binding
GD631_RS14175	COG0534	Mate efflux family protein
GD631_RS14180	COG0657	acetylesterase activity
GD631_RS14180	COG2755	lipolytic protein G-D-S-L family
GD631_RS14185	COG2205	protein histidine kinase activity
GD631_RS14185	COG0784	Response regulator, receiver
GD631_RS14195	COG0488	(ABC) transporter
GD631_RS14210	COG2198	Histidine kinase
GD631_RS14210	COG0784	Response regulator, receiver
GD631_RS14210	COG2205	protein histidine kinase activity
GD631_RS14240	COG0438	transferase activity, transferring glycosyl groups
GD631_RS14250	COG2244	polysaccharide biosynthetic process
GD631_RS14305	COG1805	sodium ion transport
GD631_RS14310	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GD631_RS14325	COG2871	sodium ion transport
GD631_RS14335	COG0513	Belongs to the DEAD box helicase family
GD631_RS14340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GD631_RS14345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GD631_RS14355	COG1739	Uncharacterized protein family UPF0029
GD631_RS14370	COG0778	Nitroreductase
GD631_RS14375	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GD631_RS14375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GD631_RS14380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD631_RS14385	COG0357	Ribosomal RNA small subunit methyltransferase G
GD631_RS14400	COG1408	metallophosphoesterase
GD631_RS14420	COG2217	Heavy metal translocating P-type atpase
GD631_RS14430	COG0321	lipoyl(octanoyl) transferase activity
GD631_RS14440	COG2755	lipolytic protein G-D-S-L family
GD631_RS14440	COG0657	acetylesterase activity
GD631_RS14460	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GD631_RS14470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GD631_RS14485	COG1678	Uncharacterized ACR, COG1678
GD631_RS14565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GD631_RS14580	COG3969	phosphoadenosine phosphosulfate
GD631_RS14585	COG1475	DNA binding
GD631_RS14650	COG0745	RESPONSE REGULATOR receiver
GD631_RS14710	COG1629	transport
GD631_RS14710	COG4206	TonB-dependent receptor
GD631_RS14750	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
GD631_RS14755	COG3537	Alpha-1,2-mannosidase
GD631_RS14775	COG4771	TonB-dependent receptor
GD631_RS14805	COG3408	Glycogen debranching enzyme
GD631_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS14845	COG3408	Glycogen debranching enzyme
GD631_RS14855	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS14875	COG0745	RESPONSE REGULATOR receiver
GD631_RS14880	COG3275	phosphorelay sensor kinase activity
GD631_RS14885	COG3279	Response regulator of the LytR AlgR family
GD631_RS14930	COG1629	transport
GD631_RS14930	COG4206	TonB-dependent receptor
GD631_RS14995	COG4232	protein-disulfide reductase activity
GD631_RS15030	COG3420	alginic acid biosynthetic process
GD631_RS15055	COG4771	TonB-dependent receptor
GD631_RS15085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GD631_RS15095	COG2731	YhcH YjgK YiaL family protein
GD631_RS15100	COG2814	Major facilitator Superfamily
GD631_RS15120	COG3250	beta-galactosidase activity
GD631_RS15130	COG3250	beta-galactosidase activity
GD631_RS15135	COG3250	beta-galactosidase activity
GD631_RS15140	COG0745	RESPONSE REGULATOR receiver
GD631_RS15145	COG5002	protein histidine kinase activity
GD631_RS15165	COG3328	transposase activity
GD631_RS15215	COG3250	beta-galactosidase activity
GD631_RS15220	COG3292	Two component regulator propeller
GD631_RS15220	COG2205	protein histidine kinase activity
GD631_RS15220	COG0745	RESPONSE REGULATOR receiver
GD631_RS15250	COG2966	Psort location CytoplasmicMembrane, score
GD631_RS15265	COG0300	oxidoreductase activity
GD631_RS15270	COG1011	Hydrolase
GD631_RS15305	COG0656	L-ascorbic acid biosynthetic process
GD631_RS15325	COG4771	TonB-dependent receptor
GD631_RS15335	COG3292	Two component regulator propeller
GD631_RS15335	COG0745	RESPONSE REGULATOR receiver
GD631_RS15335	COG2205	protein histidine kinase activity
GD631_RS15370	COG0442	prolyl-tRNA aminoacylation
GD631_RS15375	COG0745	RESPONSE REGULATOR receiver
GD631_RS15380	COG2205	protein histidine kinase activity
GD631_RS15410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GD631_RS15420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GD631_RS15425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GD631_RS15435	COG0552	protein localization to endoplasmic reticulum
GD631_RS15440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GD631_RS15455	COG0714	Associated with various cellular activities
GD631_RS15470	COG2304	oxidoreductase activity
GD631_RS15515	COG0542	response to heat
GD631_RS15520	COG0326	Molecular chaperone. Has ATPase activity
GD631_RS15525	COG1752	Esterase of the alpha-beta hydrolase superfamily
GD631_RS15570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GD631_RS15575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GD631_RS15580	COG0336	Belongs to the RNA methyltransferase TrmD family
GD631_RS15585	COG0167	dihydroorotate dehydrogenase activity
GD631_RS15590	COG0543	2 iron, 2 sulfur cluster binding
GD631_RS15605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GD631_RS15620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS15625	COG1538	Outer membrane efflux protein
GD631_RS15635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GD631_RS15650	COG4988	ABC transporter
GD631_RS15700	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GD631_RS15705	COG1597	lipid kinase activity
GD631_RS15710	COG0156	8-amino-7-oxononanoate synthase activity
GD631_RS15720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GD631_RS15910	COG0616	signal peptide processing
GD631_RS15980	COG1396	sequence-specific DNA binding
GD631_RS16000	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GD631_RS16005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GD631_RS16020	COG0110	maltose O-acetyltransferase activity
GD631_RS16030	COG3830	Belongs to the UPF0237 family
GD631_RS16030	COG0560	Phosphoserine phosphatase
GD631_RS16035	COG0513	Belongs to the DEAD box helicase family
GD631_RS16070	COG0246	Mannitol dehydrogenase
GD631_RS16075	COG1609	Transcriptional regulator
GD631_RS16080	COG1904	glucuronate isomerase
GD631_RS16100	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GD631_RS16140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GD631_RS16155	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GD631_RS16165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GD631_RS16175	COG3153	acetyltransferase
GD631_RS16175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GD631_RS16185	COG2814	Major facilitator Superfamily
GD631_RS16185	COG0477	Major facilitator Superfamily
GD631_RS16190	COG2115	Belongs to the xylose isomerase family
GD631_RS16205	COG0351	phosphomethylpyrimidine kinase
GD631_RS16210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GD631_RS16215	COG0045	succinate-CoA ligase (ADP-forming) activity
GD631_RS16220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GD631_RS16235	COG3279	Response regulator of the LytR AlgR family
GD631_RS16275	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
GD631_RS16280	COG0348	domain, Protein
GD631_RS16300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GD631_RS16305	COG2731	YhcH YjgK YiaL family protein
GD631_RS16315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD631_RS16345	COG2205	protein histidine kinase activity
GD631_RS16350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GD631_RS16365	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GD631_RS16375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GD631_RS16410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GD631_RS16425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GD631_RS16430	COG1216	Glycosyl transferase, family 2
GD631_RS16435	COG1216	Glycosyl transferase, family 2
GD631_RS16440	COG1216	Glycosyl transferase, family 2
GD631_RS16465	COG4974	Belongs to the 'phage' integrase family
GD631_RS16485	COG0540	Belongs to the ATCase OTCase family
GD631_RS16490	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GD631_RS16505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GD631_RS16510	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GD631_RS16515	COG2985	domain, Protein
GD631_RS16535	COG2207	Transcriptional regulator
GD631_RS16535	COG1917	Cupin 2, conserved barrel domain protein
GD631_RS16540	COG2207	Transcriptional regulator
GD631_RS16550	COG1690	Belongs to the RtcB family
GD631_RS16565	COG2431	L-lysine efflux transmembrane transporter activity
GD631_RS16570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GD631_RS16575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GD631_RS16580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GD631_RS16585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GD631_RS16590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GD631_RS16595	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GD631_RS16600	COG0356	it plays a direct role in the translocation of protons across the membrane
GD631_RS16610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GD631_RS16615	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GD631_RS16620	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GD631_RS16625	COG0454	-acetyltransferase
GD631_RS16635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GD631_RS16635	COG2755	lipolytic protein G-D-S-L family
GD631_RS16660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GD631_RS16670	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GD631_RS16675	COG1011	Hydrolase
GD631_RS16680	COG0534	Mate efflux family protein
GD631_RS16690	COG1136	(ABC) transporter
GD631_RS16690	COG0577	efflux transmembrane transporter activity
GD631_RS16705	COG2204	response regulator
GD631_RS16720	COG1151	hydroxylamine reductase activity
GD631_RS16725	COG2233	PERMEase
GD631_RS16730	COG3263	regulation of cellular component size
GD631_RS16735	COG0318	PFAM AMP-dependent synthetase and ligase
GD631_RS16740	COG0745	RESPONSE REGULATOR receiver
GD631_RS16745	COG5002	protein histidine kinase activity
GD631_RS16745	COG3850	Histidine kinase
GD631_RS16765	COG3118	belongs to the thioredoxin family
GD631_RS16845	COG0681	Belongs to the peptidase S26 family
GD631_RS16945	COG2205	protein histidine kinase activity
GD631_RS16945	COG2202	Pas domain
GD631_RS16955	COG0352	thiamine-phosphate diphosphorylase activity
GD631_RS16960	COG2022	thiamine diphosphate biosynthetic process
GD631_RS16965	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GD631_RS16975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GD631_RS16980	COG0352	thiamine-phosphate diphosphorylase activity
GD631_RS17000	COG0574	Belongs to the PEP-utilizing enzyme family
GD631_RS17000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GD631_RS17005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GD631_RS17010	COG0564	pseudouridine synthase activity
GD631_RS17025	COG0024	Methionine aminopeptidase
GD631_RS17040	COG0481	GTPase activity
GD631_RS17055	COG0708	Exodeoxyribonuclease III
GD631_RS17070	COG0217	transcriptional regulatory protein
GD631_RS17075	COG0072	phenylalanine-tRNA ligase activity
GD631_RS17075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GD631_RS17080	COG0305	Participates in initiation and elongation during chromosome replication
GD631_RS17085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GD631_RS17090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GD631_RS17095	COG4657	Part of a membrane complex involved in electron transport
GD631_RS17100	COG4660	Part of a membrane complex involved in electron transport
GD631_RS17105	COG4659	FMN binding
GD631_RS17110	COG4658	electron transport chain
GD631_RS17115	COG4656	Part of a membrane complex involved in electron transport
GD631_RS17210	COG1216	Glycosyl transferase, family 2
GD631_RS17220	COG2076	Multidrug Resistance protein
GD631_RS17245	COG0110	maltose O-acetyltransferase activity
GD631_RS17265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GD631_RS17290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GD631_RS17315	COG0504	CTP synthase activity
GD631_RS17320	COG0706	membrane insertase activity
GD631_RS17325	COG0534	Mate efflux family protein
GD631_RS17360	COG0515	serine threonine protein kinase
GD631_RS17360	COG2815	serine threonine protein kinase
GD631_RS17370	COG0823	Involved in the tonB-independent uptake of proteins
GD631_RS17370	COG1506	peptidase
GD631_RS17385	COG1983	PspC domain protein
GD631_RS17405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GD631_RS17415	COG1388	LysM domain
GD631_RS17415	COG3942	CHAP domain
GD631_RS17445	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GD631_RS17450	COG0556	nucleotide-excision repair
GD631_RS17465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GD631_RS17475	COG0842	Transport permease protein
GD631_RS17480	COG0842	Transport permease protein
GD631_RS17485	COG1131	(ABC) transporter
GD631_RS17490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS17500	COG1917	Cupin 2, conserved barrel domain protein
GD631_RS17500	COG2207	Transcriptional regulator
GD631_RS17505	COG0662	Cupin 2, conserved barrel domain protein
GD631_RS17505	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GD631_RS17510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GD631_RS17515	COG0505	Belongs to the CarA family
GD631_RS17525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GD631_RS17530	COG0067	glutamate synthase
GD631_RS17530	COG0069	glutamate synthase activity
GD631_RS17530	COG0070	glutamate synthase
GD631_RS17540	COG0367	asparagine synthase
GD631_RS17555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GD631_RS17560	COG0436	Aminotransferase
GD631_RS17570	COG0347	Belongs to the P(II) protein family
GD631_RS17575	COG0004	ammonium transporteR
GD631_RS17625	COG1629	transport
GD631_RS17630	COG3250	beta-galactosidase activity
GD631_RS17635	COG0745	RESPONSE REGULATOR receiver
GD631_RS17635	COG3292	Two component regulator propeller
GD631_RS17635	COG2205	protein histidine kinase activity
GD631_RS17635	COG2205	protein histidine kinase activity
GD631_RS17635	COG0745	RESPONSE REGULATOR receiver
GD631_RS17635	COG3292	Two component regulator propeller
GD631_RS17645	COG0490	domain, Protein
GD631_RS17645	COG0471	metal ion transport
GD631_RS17650	COG2202	Pas domain
GD631_RS17650	COG2205	protein histidine kinase activity
GD631_RS17655	COG1979	alcohol dehydrogenase
GD631_RS17665	COG0133	tryptophan synthase activity
GD631_RS17670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GD631_RS17680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GD631_RS17685	COG0134	indole-3-glycerol-phosphate synthase activity
GD631_RS17690	COG0135	phosphoribosylanthranilate isomerase activity
GD631_RS17695	COG0159	tryptophan synthase activity
GD631_RS17700	COG0252	asparaginase activity
GD631_RS17710	COG0745	RESPONSE REGULATOR receiver
GD631_RS17740	COG0138	bifunctional purine biosynthesis protein purh
GD631_RS17745	COG0716	FMN binding
GD631_RS17755	COG1730	sister chromatid segregation
GD631_RS17760	COG3487	Iron-regulated protein
GD631_RS17785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD631_RS17785	COG1333	cytochrome c biogenesis protein
GD631_RS17790	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS17800	COG4771	TonB-dependent receptor
GD631_RS17810	COG4771	TonB-dependent receptor
GD631_RS17820	COG0490	domain, Protein
GD631_RS17820	COG2985	domain, Protein
GD631_RS17840	COG1609	Transcriptional regulator
GD631_RS17845	COG2721	sulfolactate sulfo-lyase activity
GD631_RS17880	COG4452	Inner membrane protein CreD
GD631_RS17900	COG1733	regulation of RNA biosynthetic process
GD631_RS17910	COG5002	protein histidine kinase activity
GD631_RS17915	COG2198	Histidine kinase
GD631_RS17915	COG0784	Response regulator, receiver
GD631_RS17915	COG2205	protein histidine kinase activity
GD631_RS17925	COG3275	phosphorelay sensor kinase activity
GD631_RS17950	COG0228	four-way junction DNA binding
GD631_RS17960	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
GD631_RS17970	COG1070	Carbohydrate kinase
GD631_RS17980	COG0738	Major facilitator superfamily
GD631_RS17995	COG4771	TonB-dependent receptor
GD631_RS18050	COG1177	transmembrane transport
GD631_RS18055	COG1176	ABC-type spermidine putrescine transport system, permease component I
GD631_RS18060	COG3842	ATPase activity
GD631_RS18065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD631_RS18070	COG0058	SHG alpha-glucan phosphorylase activity
GD631_RS18080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GD631_RS18100	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
GD631_RS18140	COG3328	transposase activity
GD631_RS18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GD631_RS18165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GD631_RS18170	COG4948	Mandelate Racemase Muconate Lactonizing
GD631_RS18185	COG1295	ribonuclease BN
GD631_RS18200	COG0704	Plays a role in the regulation of phosphate uptake
GD631_RS18205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GD631_RS18210	COG0581	inorganic phosphate transmembrane transporter activity
GD631_RS18215	COG0573	inorganic phosphate transmembrane transporter activity
GD631_RS18225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GD631_RS18235	COG0586	Pfam SNARE associated Golgi protein
GD631_RS18245	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GD631_RS18260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GD631_RS18265	COG0167	dihydroorotate dehydrogenase activity
GD631_RS18270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GD631_RS18320	COG3023	N-Acetylmuramoyl-L-alanine amidase
GD631_RS18330	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GD631_RS18335	COG0438	transferase activity, transferring glycosyl groups
GD631_RS18335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GD631_RS18365	COG0582	viral genome integration into host DNA
GD631_RS18395	COG3958	Transketolase
GD631_RS18400	COG3959	Transketolase, thiamine diphosphate binding domain
GD631_RS18455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GD631_RS18460	COG0497	DNA recombination
GD631_RS18475	COG0592	DNA-directed DNA polymerase activity
GD631_RS18490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GD631_RS18490	COG0321	lipoyl(octanoyl) transferase activity
GD631_RS18495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GD631_RS18505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD631_RS18510	COG0156	8-amino-7-oxononanoate synthase activity
GD631_RS18530	COG0019	diaminopimelate decarboxylase activity
GD631_RS18535	COG0527	aspartate kinase activity
GD631_RS18540	COG2884	Cell division ATP-binding protein ftsE
GD631_RS18545	COG0140	phosphoribosyl-ATP diphosphatase activity
GD631_RS18545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GD631_RS18550	COG0107	imidazoleglycerol-phosphate synthase activity
GD631_RS18555	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GD631_RS18560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GD631_RS18565	COG0788	formyltetrahydrofolate deformylase activity
GD631_RS18630	COG0667	Aldo Keto reductase
GD631_RS18645	COG0693	protein deglycase activity
GD631_RS18660	COG0534	Mate efflux family protein
GD631_RS18670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GD631_RS18685	COG4884	unkown
GD631_RS18685	COG3831	ATPase activity
GD631_RS18690	COG2885	chlorophyll binding
GD631_RS18690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GD631_RS18715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GD631_RS18735	COG2814	Major facilitator Superfamily
GD631_RS18750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GD631_RS18765	COG0823	Involved in the tonB-independent uptake of proteins
GD631_RS18765	COG4946	Tricorn protease homolog
GD631_RS18765	COG1506	peptidase
GD631_RS18775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GD631_RS18855	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD631_RS18865	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GD631_RS18880	COG4771	TonB-dependent receptor
GD631_RS18905	COG0702	epimerase
GD631_RS18910	COG4771	TonB-dependent receptor
GD631_RS18965	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GD631_RS18970	COG5002	protein histidine kinase activity
GD631_RS18980	COG1312	Catalyzes the dehydration of D-mannonate
GD631_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS18990	COG1609	Transcriptional regulator
GD631_RS19005	COG2223	nitrite transmembrane transporter activity
GD631_RS19015	COG4771	TonB-dependent receptor
GD631_RS19025	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GD631_RS19025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GD631_RS19040	COG2226	methyltransferase
GD631_RS19055	COG2198	Histidine kinase
GD631_RS19055	COG0784	Response regulator, receiver
GD631_RS19055	COG2205	protein histidine kinase activity
GD631_RS19060	COG0511	ligase activity, forming carbon-carbon bonds
GD631_RS19065	COG0439	Biotin carboxylase
GD631_RS19070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GD631_RS19085	COG1620	l-lactate permease
GD631_RS19105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GD631_RS19110	COG1690	Belongs to the RtcB family
GD631_RS19120	COG3279	Response regulator of the LytR AlgR family
GD631_RS19155	COG0628	permease
GD631_RS19160	COG1215	transferase activity, transferring glycosyl groups
GD631_RS19165	COG0456	acetyltransferase
GD631_RS19170	COG0189	ligase activity
GD631_RS19170	COG0569	domain protein
GD631_RS19175	COG1136	(ABC) transporter
GD631_RS19175	COG0577	efflux transmembrane transporter activity
GD631_RS19180	COG0436	Aminotransferase
GD631_RS19205	COG0488	(ABC) transporter
GD631_RS19220	COG0745	RESPONSE REGULATOR receiver
GD631_RS19230	COG1472	Belongs to the glycosyl hydrolase 3 family
GD631_RS19235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GD631_RS19250	COG4771	TonB-dependent receptor
GD631_RS19270	COG4206	TonB-dependent receptor
GD631_RS19285	COG3033	Beta-eliminating lyase
GD631_RS19310	COG0629	single-stranded DNA binding
GD631_RS19315	COG1194	a g-specific adenine glycosylase
GD631_RS19325	COG1530	ribonuclease E activity
GD631_RS19335	COG1979	alcohol dehydrogenase
GD631_RS19350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GD631_RS19360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GD631_RS19375	COG4191	Histidine kinase
GD631_RS19380	COG2204	response regulator
GD631_RS19400	COG0577	efflux transmembrane transporter activity
GD631_RS19410	COG1136	(ABC) transporter
GD631_RS19420	COG1252	NADH dehydrogenase
GD631_RS19425	COG1705	Flagellar rod assembly protein muramidase FlgJ
GD631_RS19430	COG0295	cytidine deaminase activity
GD631_RS19440	COG3059	membrane
GD631_RS19445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GD631_RS19450	COG0488	(ABC) transporter
GD631_RS19465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GD631_RS19485	COG1629	transport
GD631_RS19485	COG4206	TonB-dependent receptor
GD631_RS19500	COG0686	Belongs to the AlaDH PNT family
GD631_RS19540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GD631_RS19550	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GD631_RS19555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GD631_RS19565	COG1595	DNA-templated transcription, initiation
GD631_RS19580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GD631_RS19585	COG1741	Belongs to the pirin family
GD631_RS19590	COG0259	pyridoxamine-phosphate oxidase activity
GD631_RS19605	COG0346	lactoylglutathione lyase activity
GD631_RS19660	COG1918	ferrous iron import across plasma membrane
GD631_RS19660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GD631_RS19665	COG0037	tRNA processing
GD631_RS19680	COG3119	arylsulfatase activity
GD631_RS19685	COG2205	protein histidine kinase activity
GD631_RS19685	COG2202	Pas domain
GD631_RS19690	COG2202	Pas domain
GD631_RS19690	COG2205	protein histidine kinase activity
GD631_RS19695	COG0534	Mate efflux family protein
GD631_RS19700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GD631_RS19710	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD631_RS19715	COG1858	cytochrome C peroxidase
GD631_RS19720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GD631_RS19745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GD631_RS19770	COG2195	Cleaves the N-terminal amino acid of tripeptides
GD631_RS19780	COG0668	transmembrane transport
GD631_RS19800	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GD631_RS19815	COG0348	domain, Protein
GD631_RS19855	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GD631_RS19860	COG1830	Aldolase
GD631_RS19865	COG0588	phosphoglycerate mutase activity
GD631_RS19880	COG1119	ATPase activity
GD631_RS19885	COG3661	Belongs to the glycosyl hydrolase 67 family
GD631_RS19900	COG2211	Major facilitator Superfamily
GD631_RS19920	COG0561	phosphatase activity
GD631_RS19925	COG1629	transport
GD631_RS19925	COG4206	TonB-dependent receptor
GD631_RS19935	COG1523	belongs to the glycosyl hydrolase 13 family
GD631_RS19940	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GD631_RS19980	COG0702	epimerase
GD631_RS19995	COG0582	viral genome integration into host DNA
GD631_RS20050	COG4717	serine-type aminopeptidase activity
GD631_RS20070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GD631_RS20075	COG2814	Major facilitator Superfamily
GD631_RS20080	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GD631_RS20085	COG0126	phosphoglycerate kinase activity
GD631_RS20100	COG2311	Membrane
GD631_RS20110	COG0424	maF-like protein
GD631_RS20130	COG0778	Nitroreductase
GD631_RS20140	COG0288	reversible hydration of carbon dioxide
GD631_RS20150	COG4771	TonB-dependent receptor
GD631_RS20165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GD631_RS20175	COG0511	ligase activity, forming carbon-carbon bonds
GD631_RS20180	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GD631_RS20185	COG0191	fructose-bisphosphate aldolase activity
GD631_RS20190	COG0254	rRNA binding
GD631_RS20210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GD631_RS20235	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GD631_RS20260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GD631_RS20275	COG1280	lysine exporter protein (LysE YggA)
GD631_RS20285	COG3292	Two component regulator propeller
GD631_RS20285	COG2205	protein histidine kinase activity
GD631_RS20285	COG0745	RESPONSE REGULATOR receiver
GD631_RS20285	COG3292	Two component regulator propeller
GD631_RS20285	COG0745	RESPONSE REGULATOR receiver
GD631_RS20285	COG2205	protein histidine kinase activity
GD631_RS20300	COG1649	PFAM Uncharacterised BCR, COG1649
GD631_RS20315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GD631_RS20330	COG1966	Carbon starvation protein
GD631_RS20335	COG1649	PFAM Uncharacterised BCR, COG1649
GD631_RS20360	COG4176	ABC-type proline glycine betaine transport system permease component
GD631_RS20370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GD631_RS20380	COG3292	Two component regulator propeller
GD631_RS20380	COG2205	protein histidine kinase activity
GD631_RS20380	COG0745	RESPONSE REGULATOR receiver
GD631_RS20385	COG4206	TonB-dependent receptor
GD631_RS20385	COG1629	transport
GD631_RS20390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GD631_RS20390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GD631_RS20405	COG1621	beta-fructofuranosidase activity
GD631_RS20420	COG0561	phosphatase activity
GD631_RS20425	COG1629	transport
GD631_RS20425	COG4206	TonB-dependent receptor
GD631_RS20440	COG1621	beta-fructofuranosidase activity
GD631_RS20455	COG0475	glutathione-regulated potassium exporter activity
GD631_RS20505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GD631_RS20510	COG1960	acyl-CoA dehydrogenase activity
GD631_RS20515	COG0705	Rhomboid family
GD631_RS20530	COG1956	GAF domain-containing protein
GD631_RS20540	COG0484	heat shock protein binding
GD631_RS20545	COG2194	sulfuric ester hydrolase activity
GD631_RS20565	COG0028	Belongs to the TPP enzyme family
GD631_RS20595	COG0459	protein refolding
GD631_RS20600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GD631_RS20630	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GD631_RS20640	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GD631_RS20645	COG0124	histidyl-tRNA synthetase
GD631_RS20660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GD631_RS20685	COG0514	ATP-dependent DNA helicase (RecQ)
GD631_RS20695	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GD631_RS20700	COG1368	sulfuric ester hydrolase activity
GD631_RS20705	COG0671	phosphoesterase, PA-phosphatase related
GD631_RS20710	COG0473	3-isopropylmalate dehydrogenase activity
GD631_RS20720	COG0066	3-isopropylmalate dehydratase activity
GD631_RS20725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GD631_RS20730	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GD631_RS20805	COG4977	sequence-specific DNA binding
GD631_RS20805	COG1917	Cupin 2, conserved barrel domain protein
GD631_RS20830	COG1028	Short-chain dehydrogenase reductase Sdr
GD631_RS20840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GD631_RS20845	COG3118	belongs to the thioredoxin family
GD631_RS20850	COG0439	Biotin carboxylase
GD631_RS20860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GD631_RS20870	COG2873	o-acetylhomoserine
GD631_RS20880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GD631_RS20890	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GD631_RS20895	COG1088	dTDP-glucose 4,6-dehydratase activity
GD631_RS20900	COG1575	Belongs to the MenA family. Type 1 subfamily
GD631_RS20905	COG1408	metallophosphoesterase
GD631_RS20915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GD631_RS20925	COG0194	GDP metabolic process
GD631_RS20945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GD631_RS20950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GD631_RS20960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GD631_RS20965	COG0750	zinc metalloprotease
GD631_RS20975	COG1328	CTP reductase activity
GD631_RS21015	COG3023	N-Acetylmuramoyl-L-alanine amidase
GD631_RS21035	COG1538	Outer membrane efflux protein
GD631_RS21060	COG2814	Major facilitator Superfamily
GD631_RS21085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GD631_RS21100	COG0561	phosphatase activity
GD631_RS21105	COG4771	TonB-dependent receptor
GD631_RS21130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GD631_RS21180	COG1505	serine-type exopeptidase activity
GD631_RS21195	COG0617	tRNA 3'-terminal CCA addition
GD631_RS21210	COG0632	four-way junction helicase activity
GD631_RS21215	COG0673	inositol 2-dehydrogenase activity
GD631_RS21220	COG1272	protein, Hemolysin III
GD631_RS21230	COG4206	TonB-dependent receptor
GD631_RS21230	COG1629	transport
GD631_RS21235	COG1629	transport
GD631_RS21245	COG2204	response regulator
GD631_RS21250	COG0488	(ABC) transporter
GD631_RS21290	COG1595	DNA-templated transcription, initiation
GD631_RS21305	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GD631_RS21315	COG1522	sequence-specific DNA binding
GD631_RS21345	COG4771	TonB-dependent receptor
GD631_RS21380	COG0811	peptide transport
GD631_RS21390	COG0084	hydrolase, TatD family'
GD631_RS21410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GD631_RS21415	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GD631_RS21420	COG0205	6-phosphofructokinase activity
GD631_RS21440	COG0372	Belongs to the citrate synthase family
GD631_RS21450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GD631_RS21455	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GD631_RS21460	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GD631_RS21475	COG0028	Belongs to the TPP enzyme family
GD631_RS21480	COG0129	dihydroxy-acid dehydratase activity
GD631_RS21490	COG3681	Belongs to the UPF0597 family
GD631_RS21510	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GD631_RS21585	COG1629	transport
GD631_RS21585	COG4206	TonB-dependent receptor
GD631_RS21595	COG1595	DNA-templated transcription, initiation
GD631_RS21600	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GD631_RS21600	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GD631_RS21605	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GD631_RS21610	COG0569	domain protein
GD631_RS21610	COG2985	domain, Protein
GD631_RS21650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD631_RS21685	COG0702	epimerase
GD631_RS21690	COG1629	transport
GD631_RS21690	COG4206	TonB-dependent receptor
GD631_RS21695	COG1940	carbohydrate kinase activity
GD631_RS21705	COG2188	Transcriptional regulator
GD631_RS21745	COG2207	Transcriptional regulator
GD631_RS21745	COG1609	Transcriptional regulator
GD631_RS21750	COG3292	Two component regulator propeller
GD631_RS21750	COG0745	RESPONSE REGULATOR receiver
GD631_RS21750	COG2205	protein histidine kinase activity
GD631_RS21750	COG0745	RESPONSE REGULATOR receiver
GD631_RS21750	COG2205	protein histidine kinase activity
GD631_RS21750	COG3292	Two component regulator propeller
GD631_RS21770	COG1629	transport
GD631_RS21790	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GD631_RS21800	COG3119	arylsulfatase activity
GD631_RS21830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GD631_RS21835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GD631_RS21840	COG0166	Belongs to the GPI family
GD631_RS21855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GD631_RS21875	COG2502	aspartate--ammonia ligase
GD631_RS21880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GD631_RS21895	COG3876	Protein conserved in bacteria
GD631_RS21925	COG2315	Protein conserved in bacteria
GD631_RS21990	COG0358	DNA primase activity
GD631_RS22020	COG0860	N-Acetylmuramoyl-L-alanine amidase