locus-tag	class	description
NXX57_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXX57_RS00010	COG0778	Nitroreductase
NXX57_RS00020	COG1640	4-alpha-glucanotransferase
NXX57_RS00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NXX57_RS00055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX57_RS00060	COG0318	PFAM AMP-dependent synthetase and ligase
NXX57_RS00095	COG0359	binds to the 23S rRNA
NXX57_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXX57_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
NXX57_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXX57_RS00135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXX57_RS00190	COG1131	(ABC) transporter
NXX57_RS00205	COG2431	L-lysine efflux transmembrane transporter activity
NXX57_RS00215	COG1193	negative regulation of DNA recombination
NXX57_RS00250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXX57_RS00265	COG2234	aminopeptidase activity
NXX57_RS00270	COG3250	beta-galactosidase activity
NXX57_RS00290	COG0702	epimerase
NXX57_RS00295	COG1629	transport
NXX57_RS00310	COG3537	Alpha-1,2-mannosidase
NXX57_RS00325	COG4206	TonB-dependent receptor
NXX57_RS00325	COG1629	transport
NXX57_RS00345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXX57_RS00350	COG0802	atpase or kinase
NXX57_RS00375	COG0714	Associated with various cellular activities
NXX57_RS00420	COG3118	belongs to the thioredoxin family
NXX57_RS00430	COG0688	phosphatidylethanolamine metabolic process
NXX57_RS00435	COG1183	phosphatidylcholine synthase activity
NXX57_RS00455	COG0792	nuclease activity
NXX57_RS00480	COG0534	Mate efflux family protein
NXX57_RS00485	COG0528	UMP kinase activity
NXX57_RS00525	COG0233	cytoplasmic translational termination
NXX57_RS00530	COG1162	GTPase activity
NXX57_RS00540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXX57_RS00560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXX57_RS00560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXX57_RS00570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXX57_RS00580	COG4206	TonB-dependent receptor
NXX57_RS00580	COG1629	transport
NXX57_RS00600	COG1629	transport
NXX57_RS00665	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS00725	COG0740	serine-type endopeptidase activity
NXX57_RS00855	COG4206	TonB-dependent receptor
NXX57_RS00855	COG1629	transport
NXX57_RS00865	COG2095	MarC family integral membrane protein
NXX57_RS00880	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXX57_RS00890	COG1435	thymidine kinase activity
NXX57_RS00895	COG0628	permease
NXX57_RS00930	COG0534	Mate efflux family protein
NXX57_RS00995	COG1396	sequence-specific DNA binding
NXX57_RS01015	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX57_RS01030	COG0745	RESPONSE REGULATOR receiver
NXX57_RS01030	COG2205	protein histidine kinase activity
NXX57_RS01030	COG3292	Two component regulator propeller
NXX57_RS01045	COG0702	epimerase
NXX57_RS01050	COG1629	transport
NXX57_RS01060	COG4771	TonB-dependent receptor
NXX57_RS01070	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS01085	COG4771	TonB-dependent receptor
NXX57_RS01120	COG0693	protein deglycase activity
NXX57_RS01185	COG0110	maltose O-acetyltransferase activity
NXX57_RS01195	COG1522	sequence-specific DNA binding
NXX57_RS01220	COG3292	Two component regulator propeller
NXX57_RS01220	COG0745	RESPONSE REGULATOR receiver
NXX57_RS01220	COG2205	protein histidine kinase activity
NXX57_RS01235	COG1629	transport
NXX57_RS01260	COG2818	Glycosylase
NXX57_RS01265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXX57_RS01270	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXX57_RS01280	COG0252	asparaginase activity
NXX57_RS01290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXX57_RS01295	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXX57_RS01305	COG4771	TonB-dependent receptor
NXX57_RS01325	COG0826	peptidase U32
NXX57_RS01330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXX57_RS01340	COG0436	Aminotransferase
NXX57_RS01345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXX57_RS01425	COG3119	arylsulfatase activity
NXX57_RS01430	COG3119	arylsulfatase activity
NXX57_RS01435	COG3119	arylsulfatase activity
NXX57_RS01455	COG0702	epimerase
NXX57_RS01460	COG1629	transport
NXX57_RS01460	COG4206	TonB-dependent receptor
NXX57_RS01470	COG1629	transport
NXX57_RS01475	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX57_RS01515	COG2314	TM2 domain
NXX57_RS01575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXX57_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS01625	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NXX57_RS01640	COG1086	Polysaccharide biosynthesis protein
NXX57_RS01695	COG1629	transport
NXX57_RS01730	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS01805	COG0519	Catalyzes the synthesis of GMP from XMP
NXX57_RS01810	COG5002	protein histidine kinase activity
NXX57_RS01815	COG2205	protein histidine kinase activity
NXX57_RS01825	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXX57_RS01835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXX57_RS01880	COG3250	beta-galactosidase activity
NXX57_RS01885	COG2204	response regulator
NXX57_RS01890	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXX57_RS01920	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS01925	COG0737	Belongs to the 5'-nucleotidase family
NXX57_RS01930	COG0737	Belongs to the 5'-nucleotidase family
NXX57_RS01970	COG0335	large ribosomal subunit rRNA binding
NXX57_RS01985	COG1940	carbohydrate kinase activity
NXX57_RS01990	COG0577	efflux transmembrane transporter activity
NXX57_RS01990	COG1136	(ABC) transporter
NXX57_RS01995	COG0577	efflux transmembrane transporter activity
NXX57_RS01995	COG1136	(ABC) transporter
NXX57_RS02000	COG0577	efflux transmembrane transporter activity
NXX57_RS02000	COG1136	(ABC) transporter
NXX57_RS02005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS02010	COG1538	Outer membrane efflux protein
NXX57_RS02015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXX57_RS02015	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXX57_RS02025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXX57_RS02045	COG2996	Protein conserved in bacteria
NXX57_RS02050	COG0039	L-malate dehydrogenase activity
NXX57_RS02060	COG2217	Heavy metal translocating P-type atpase
NXX57_RS02075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXX57_RS02080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXX57_RS02085	COG0509	glycine decarboxylation via glycine cleavage system
NXX57_RS02100	COG0514	ATP-dependent DNA helicase (RecQ)
NXX57_RS02115	COG0006	proline dipeptidase activity
NXX57_RS02120	COG3250	beta-galactosidase activity
NXX57_RS02125	COG3408	Glycogen debranching enzyme
NXX57_RS02130	COG3458	cephalosporin-C deacetylase activity
NXX57_RS02145	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXX57_RS02160	COG4206	TonB-dependent receptor
NXX57_RS02160	COG1629	transport
NXX57_RS02190	COG1773	rubredoxin
NXX57_RS02195	COG2205	protein histidine kinase activity
NXX57_RS02195	COG2202	Pas domain
NXX57_RS02200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXX57_RS02205	COG1011	Hydrolase
NXX57_RS02210	COG0196	riboflavin kinase activity
NXX57_RS02215	COG1266	CAAX protease self-immunity
NXX57_RS02225	COG3655	Transcriptional regulator
NXX57_RS02230	COG2166	iron-sulfur cluster assembly
NXX57_RS02235	COG2234	aminopeptidase activity
NXX57_RS02240	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXX57_RS02250	COG0280	phosphate acetyltransferase
NXX57_RS02255	COG3426	butyrate kinase activity
NXX57_RS02280	COG4206	TonB-dependent receptor
NXX57_RS02280	COG1629	transport
NXX57_RS02295	COG1185	polyribonucleotide nucleotidyltransferase activity
NXX57_RS02305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXX57_RS02325	COG1595	DNA-templated transcription, initiation
NXX57_RS02330	COG0076	glutamate decarboxylase activity
NXX57_RS02335	COG2066	Belongs to the glutaminase family
NXX57_RS02345	COG0531	amino acid
NXX57_RS02490	COG0667	Aldo Keto reductase
NXX57_RS02495	COG3250	beta-galactosidase activity
NXX57_RS02530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS02540	COG1309	transcriptional regulator
NXX57_RS02545	COG2986	histidine ammonia-lyase
NXX57_RS02555	COG1228	amidohydrolase
NXX57_RS02565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXX57_RS02575	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXX57_RS02590	COG0203	ribosomal protein L17
NXX57_RS02595	COG0202	RNA polymerase activity
NXX57_RS02600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXX57_RS02605	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXX57_RS02610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXX57_RS02615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXX57_RS02620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXX57_RS02635	COG0200	Binds to the 23S rRNA
NXX57_RS02640	COG1841	ribosomal large subunit assembly
NXX57_RS02645	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXX57_RS02650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXX57_RS02655	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXX57_RS02660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXX57_RS02665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXX57_RS02670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXX57_RS02675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXX57_RS02680	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXX57_RS02685	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXX57_RS02690	COG0255	Belongs to the universal ribosomal protein uL29 family
NXX57_RS02695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXX57_RS02700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXX57_RS02705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXX57_RS02710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXX57_RS02715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXX57_RS02720	COG0089	rRNA binding
NXX57_RS02725	COG0088	Forms part of the polypeptide exit tunnel
NXX57_RS02730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXX57_RS02735	COG0051	transcription antitermination factor activity, RNA binding
NXX57_RS02740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXX57_RS02745	COG0049	tRNA binding
NXX57_RS02750	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXX57_RS02760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXX57_RS02765	COG0085	RNA polymerase activity
NXX57_RS02770	COG0222	ribosome binding
NXX57_RS02775	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXX57_RS02780	COG0081	regulation of translation
NXX57_RS02785	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXX57_RS02795	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXX57_RS02805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXX57_RS02835	COG4974	Belongs to the 'phage' integrase family
NXX57_RS02840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXX57_RS02845	COG0006	proline dipeptidase activity
NXX57_RS02850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXX57_RS02860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXX57_RS02870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXX57_RS02880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXX57_RS02895	COG1595	DNA-templated transcription, initiation
NXX57_RS02910	COG1027	Aspartate ammonia-lyase
NXX57_RS02915	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXX57_RS02920	COG0252	asparaginase activity
NXX57_RS02935	COG2096	Adenosyltransferase
NXX57_RS02975	COG0515	serine threonine protein kinase
NXX57_RS02975	COG2815	serine threonine protein kinase
NXX57_RS02990	COG0631	protein serine/threonine phosphatase activity
NXX57_RS03000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX57_RS03040	COG4974	Belongs to the 'phage' integrase family
NXX57_RS03045	COG4804	nuclease activity
NXX57_RS03100	COG0358	DNA primase activity
NXX57_RS03140	COG0358	DNA primase activity
NXX57_RS03160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXX57_RS03180	COG0318	PFAM AMP-dependent synthetase and ligase
NXX57_RS03185	COG1396	sequence-specific DNA binding
NXX57_RS03200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXX57_RS03215	COG2059	Chromate
NXX57_RS03220	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXX57_RS03225	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXX57_RS03255	COG0745	RESPONSE REGULATOR receiver
NXX57_RS03255	COG3292	Two component regulator propeller
NXX57_RS03255	COG2205	protein histidine kinase activity
NXX57_RS03280	COG0702	epimerase
NXX57_RS03285	COG4771	TonB-dependent receptor
NXX57_RS03305	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS03320	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXX57_RS03330	COG0793	Belongs to the peptidase S41A family
NXX57_RS03335	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX57_RS03375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX57_RS03380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX57_RS03385	COG4771	TonB-dependent receptor
NXX57_RS03390	COG0702	epimerase
NXX57_RS03420	COG3634	alkyl hydroperoxide reductase activity
NXX57_RS03430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX57_RS03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXX57_RS03440	COG2816	NAD+ diphosphatase activity
NXX57_RS03455	COG1629	transport
NXX57_RS03495	COG2205	protein histidine kinase activity
NXX57_RS03495	COG3292	Two component regulator propeller
NXX57_RS03495	COG3292	Two component regulator propeller
NXX57_RS03495	COG0745	RESPONSE REGULATOR receiver
NXX57_RS03495	COG2205	protein histidine kinase activity
NXX57_RS03495	COG0745	RESPONSE REGULATOR receiver
NXX57_RS03510	COG0018	arginyl-trna synthetase
NXX57_RS03520	COG0705	Rhomboid family
NXX57_RS03535	COG0339	signal peptide processing
NXX57_RS03540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXX57_RS03550	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXX57_RS03550	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXX57_RS03555	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXX57_RS03560	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXX57_RS03565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXX57_RS03585	COG4974	Belongs to the 'phage' integrase family
NXX57_RS03600	COG0606	chelatase, subunit chli
NXX57_RS03620	COG2205	protein histidine kinase activity
NXX57_RS03630	COG3250	beta-galactosidase activity
NXX57_RS03655	COG3634	alkyl hydroperoxide reductase activity
NXX57_RS03660	COG3250	beta-galactosidase activity
NXX57_RS03685	COG0702	epimerase
NXX57_RS03690	COG4771	TonB-dependent receptor
NXX57_RS03700	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS03705	COG3119	arylsulfatase activity
NXX57_RS03705	COG3408	Glycogen debranching enzyme
NXX57_RS03725	COG3119	arylsulfatase activity
NXX57_RS03730	COG2017	converts alpha-aldose to the beta-anomer
NXX57_RS03735	COG0702	epimerase
NXX57_RS03740	COG1629	transport
NXX57_RS03740	COG4206	TonB-dependent receptor
NXX57_RS03790	COG0673	inositol 2-dehydrogenase activity
NXX57_RS03800	COG0673	inositol 2-dehydrogenase activity
NXX57_RS03805	COG0745	RESPONSE REGULATOR receiver
NXX57_RS03805	COG3292	Two component regulator propeller
NXX57_RS03805	COG2205	protein histidine kinase activity
NXX57_RS03875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX57_RS03875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX57_RS03905	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS03935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXX57_RS03940	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS03945	COG1216	Glycosyl transferase, family 2
NXX57_RS03970	COG5492	domain, Protein
NXX57_RS03985	COG0702	epimerase
NXX57_RS03990	COG4771	TonB-dependent receptor
NXX57_RS03995	COG3250	beta-galactosidase activity
NXX57_RS04005	COG3292	Two component regulator propeller
NXX57_RS04005	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04005	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04005	COG2205	protein histidine kinase activity
NXX57_RS04005	COG2205	protein histidine kinase activity
NXX57_RS04005	COG3292	Two component regulator propeller
NXX57_RS04025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXX57_RS04030	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX57_RS04035	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX57_RS04080	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS04095	COG1629	transport
NXX57_RS04100	COG0561	phosphatase activity
NXX57_RS04110	COG0366	Alpha amylase catalytic
NXX57_RS04155	COG4771	TonB-dependent receptor
NXX57_RS04175	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXX57_RS04180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX57_RS04200	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXX57_RS04205	COG3409	Peptidoglycan-binding domain 1 protein
NXX57_RS04205	COG0793	Belongs to the peptidase S41A family
NXX57_RS04250	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS04265	COG1629	transport
NXX57_RS04270	COG2205	protein histidine kinase activity
NXX57_RS04270	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04270	COG3292	Two component regulator propeller
NXX57_RS04290	COG4771	TonB-dependent receptor
NXX57_RS04310	COG3119	arylsulfatase activity
NXX57_RS04315	COG3119	arylsulfatase activity
NXX57_RS04320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS04325	COG3119	arylsulfatase activity
NXX57_RS04340	COG1053	succinate dehydrogenase
NXX57_RS04345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXX57_RS04350	COG3119	arylsulfatase activity
NXX57_RS04395	COG4771	TonB-dependent receptor
NXX57_RS04400	COG0702	epimerase
NXX57_RS04410	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS04425	COG3345	alpha-galactosidase
NXX57_RS04430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXX57_RS04430	COG0758	DNA mediated transformation
NXX57_RS04440	COG0826	peptidase U32
NXX57_RS04450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXX57_RS04465	COG0557	exoribonuclease II activity
NXX57_RS04485	COG4206	TonB-dependent receptor
NXX57_RS04485	COG1629	transport
NXX57_RS04490	COG0561	phosphatase activity
NXX57_RS04500	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS04510	COG1917	Cupin 2, conserved barrel domain protein
NXX57_RS04515	COG1621	beta-fructofuranosidase activity
NXX57_RS04530	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX57_RS04550	COG0702	epimerase
NXX57_RS04555	COG4771	TonB-dependent receptor
NXX57_RS04580	COG3408	Glycogen debranching enzyme
NXX57_RS04580	COG3119	arylsulfatase activity
NXX57_RS04590	COG2205	protein histidine kinase activity
NXX57_RS04590	COG3292	Two component regulator propeller
NXX57_RS04590	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04595	COG3119	arylsulfatase activity
NXX57_RS04605	COG4771	TonB-dependent receptor
NXX57_RS04635	COG3119	arylsulfatase activity
NXX57_RS04645	COG1073	alpha beta
NXX57_RS04650	COG2814	Major facilitator Superfamily
NXX57_RS04655	COG0012	GTP binding
NXX57_RS04660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXX57_RS04665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXX57_RS04680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXX57_RS04685	COG0662	Cupin 2, conserved barrel domain protein
NXX57_RS04685	COG2207	Transcriptional regulator
NXX57_RS04690	COG0697	spore germination
NXX57_RS04700	COG0495	leucyl-tRNA aminoacylation
NXX57_RS04705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXX57_RS04710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXX57_RS04715	COG1360	Flagellar Motor Protein
NXX57_RS04720	COG3537	Alpha-1,2-mannosidase
NXX57_RS04740	COG3292	Two component regulator propeller
NXX57_RS04740	COG2205	protein histidine kinase activity
NXX57_RS04740	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04740	COG3292	Two component regulator propeller
NXX57_RS04740	COG2205	protein histidine kinase activity
NXX57_RS04740	COG0745	RESPONSE REGULATOR receiver
NXX57_RS04760	COG4771	TonB-dependent receptor
NXX57_RS04775	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS04785	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS04790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXX57_RS04810	COG0731	radical SAM domain protein
NXX57_RS04810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXX57_RS04820	COG3119	arylsulfatase activity
NXX57_RS04845	COG0659	secondary active sulfate transmembrane transporter activity
NXX57_RS04850	COG1592	Rubrerythrin
NXX57_RS04905	COG0427	acetyl-CoA hydrolase
NXX57_RS04915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX57_RS04975	COG2177	Part of the ABC transporter FtsEX involved in
NXX57_RS04985	COG1968	undecaprenyl-diphosphatase activity
NXX57_RS04990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXX57_RS04995	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXX57_RS05005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXX57_RS05020	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXX57_RS05070	COG0594	ribonuclease P activity
NXX57_RS05075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXX57_RS05085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXX57_RS05095	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXX57_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS05170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXX57_RS05185	COG1121	(ABC) transporter
NXX57_RS05195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXX57_RS05195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NXX57_RS05200	COG1238	metal cluster binding
NXX57_RS05220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXX57_RS05220	COG0116	Belongs to the methyltransferase superfamily
NXX57_RS05225	COG1045	serine acetyltransferase
NXX57_RS05230	COG3275	phosphorelay sensor kinase activity
NXX57_RS05235	COG3279	Response regulator of the LytR AlgR family
NXX57_RS05245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXX57_RS05245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXX57_RS05250	COG0142	geranyltranstransferase activity
NXX57_RS05265	COG1694	Mazg nucleotide pyrophosphohydrolase
NXX57_RS05270	COG1490	D-aminoacyl-tRNA deacylase activity
NXX57_RS05275	COG0322	excinuclease ABC activity
NXX57_RS05280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXX57_RS05285	COG0445	tRNA wobble uridine modification
NXX57_RS05300	COG4771	TonB-dependent receptor
NXX57_RS05355	COG2197	response regulator
NXX57_RS05365	COG4206	TonB-dependent receptor
NXX57_RS05365	COG1629	transport
NXX57_RS05385	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXX57_RS05390	COG0700	Nucleoside recognition
NXX57_RS05395	COG2255	four-way junction helicase activity
NXX57_RS05415	COG3591	Belongs to the peptidase S1B family
NXX57_RS05420	COG3250	beta-galactosidase activity
NXX57_RS05445	COG0582	viral genome integration into host DNA
NXX57_RS05460	COG0582	viral genome integration into host DNA
NXX57_RS05465	COG3250	beta-galactosidase activity
NXX57_RS05470	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS05490	COG0702	epimerase
NXX57_RS05495	COG4771	TonB-dependent receptor
NXX57_RS05515	COG0745	RESPONSE REGULATOR receiver
NXX57_RS05515	COG2205	protein histidine kinase activity
NXX57_RS05515	COG3292	Two component regulator propeller
NXX57_RS05520	COG0513	Belongs to the DEAD box helicase family
NXX57_RS05545	COG0612	Peptidase, M16
NXX57_RS05555	COG4771	TonB-dependent receptor
NXX57_RS05560	COG0702	epimerase
NXX57_RS05575	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS05585	COG0681	Belongs to the peptidase S26 family
NXX57_RS05595	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXX57_RS05605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX57_RS05630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXX57_RS05655	COG4771	TonB-dependent receptor
NXX57_RS05660	COG3119	arylsulfatase activity
NXX57_RS05665	COG0745	RESPONSE REGULATOR receiver
NXX57_RS05665	COG2205	protein histidine kinase activity
NXX57_RS05665	COG3292	Two component regulator propeller
NXX57_RS05665	COG0745	RESPONSE REGULATOR receiver
NXX57_RS05665	COG2205	protein histidine kinase activity
NXX57_RS05665	COG3292	Two component regulator propeller
NXX57_RS05675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX57_RS05680	COG1538	Outer membrane efflux protein
NXX57_RS05690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS05695	COG3250	beta-galactosidase activity
NXX57_RS05725	COG4771	TonB-dependent receptor
NXX57_RS05735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX57_RS05740	COG3119	arylsulfatase activity
NXX57_RS05745	COG5492	domain, Protein
NXX57_RS05750	COG0215	cysteine-tRNA ligase activity
NXX57_RS05755	COG0561	phosphatase activity
NXX57_RS05760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXX57_RS05765	COG0482	sulfurtransferase activity
NXX57_RS05775	COG0205	6-phosphofructokinase activity
NXX57_RS05780	COG0571	ribonuclease III activity
NXX57_RS05785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXX57_RS05790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXX57_RS05800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXX57_RS05830	COG1216	Glycosyl transferase, family 2
NXX57_RS05830	COG1442	glycosyl transferase family 8
NXX57_RS05850	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS05855	COG1216	Glycosyl transferase, family 2
NXX57_RS05870	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXX57_RS05875	COG0436	Aminotransferase
NXX57_RS05895	COG0463	Glycosyl transferase, family 2
NXX57_RS05930	COG1132	(ABC) transporter
NXX57_RS05955	COG0328	RNA-DNA hybrid ribonuclease activity
NXX57_RS05955	COG3341	Caulimovirus viroplasmin
NXX57_RS05965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXX57_RS05970	COG1166	arginine decarboxylase activity
NXX57_RS05975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NXX57_RS05980	COG1595	DNA-templated transcription, initiation
NXX57_RS06010	COG0779	Required for maturation of 30S ribosomal subunits
NXX57_RS06015	COG0195	Participates in both transcription termination and antitermination
NXX57_RS06020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXX57_RS06030	COG0719	Fe-S assembly protein
NXX57_RS06035	COG0396	ATPase activity
NXX57_RS06040	COG0719	Fe-S assembly protein
NXX57_RS06045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXX57_RS06050	COG0393	Putative heavy-metal-binding
NXX57_RS06070	COG0745	RESPONSE REGULATOR receiver
NXX57_RS06070	COG3292	Two component regulator propeller
NXX57_RS06070	COG2205	protein histidine kinase activity
NXX57_RS06070	COG3292	Two component regulator propeller
NXX57_RS06070	COG0745	RESPONSE REGULATOR receiver
NXX57_RS06070	COG3292	Two component regulator propeller
NXX57_RS06070	COG0745	RESPONSE REGULATOR receiver
NXX57_RS06070	COG2205	protein histidine kinase activity
NXX57_RS06070	COG2205	protein histidine kinase activity
NXX57_RS06075	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXX57_RS06080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXX57_RS06100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXX57_RS06115	COG0187	DNA topoisomerase II activity
NXX57_RS06120	COG0268	Binds directly to 16S ribosomal RNA
NXX57_RS06175	COG1381	Involved in DNA repair and RecF pathway recombination
NXX57_RS06230	COG1610	YqeY-like protein
NXX57_RS06235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXX57_RS06250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXX57_RS06255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXX57_RS06260	COG0772	Belongs to the SEDS family
NXX57_RS06265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXX57_RS06270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXX57_RS06275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXX57_RS06290	COG0275	rRNA processing
NXX57_RS06295	COG2001	Belongs to the MraZ family
NXX57_RS06300	COG1595	DNA-templated transcription, initiation
NXX57_RS06315	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXX57_RS06320	COG0756	dUTP diphosphatase activity
NXX57_RS06335	COG4942	peptidase
NXX57_RS06340	COG0745	RESPONSE REGULATOR receiver
NXX57_RS06340	COG2205	protein histidine kinase activity
NXX57_RS06340	COG3292	Two component regulator propeller
NXX57_RS06360	COG4771	TonB-dependent receptor
NXX57_RS06400	COG0702	epimerase
NXX57_RS06405	COG4771	TonB-dependent receptor
NXX57_RS06440	COG3119	arylsulfatase activity
NXX57_RS06455	COG1629	transport
NXX57_RS06490	COG4771	TonB-dependent receptor
NXX57_RS06495	COG0702	epimerase
NXX57_RS06530	COG3250	beta-galactosidase activity
NXX57_RS06550	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS06565	COG1629	transport
NXX57_RS06570	COG0561	phosphatase activity
NXX57_RS06605	COG3537	Alpha-1,2-mannosidase
NXX57_RS06620	COG3537	Alpha-1,2-mannosidase
NXX57_RS06630	COG2017	converts alpha-aldose to the beta-anomer
NXX57_RS06725	COG1373	ATPase (AAA superfamily
NXX57_RS06730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXX57_RS06770	COG1595	DNA-templated transcription, initiation
NXX57_RS06775	COG1022	Amp-dependent synthetase and ligase
NXX57_RS06780	COG0612	Peptidase, M16
NXX57_RS06800	COG2954	triphosphatase activity
NXX57_RS06870	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS06880	COG4771	TonB-dependent receptor
NXX57_RS06935	COG0673	inositol 2-dehydrogenase activity
NXX57_RS06945	COG0673	inositol 2-dehydrogenase activity
NXX57_RS06970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXX57_RS06980	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS06995	COG0561	phosphatase activity
NXX57_RS07000	COG4771	TonB-dependent receptor
NXX57_RS07015	COG2207	Transcriptional regulator
NXX57_RS07015	COG1609	Transcriptional regulator
NXX57_RS07020	COG0423	glycine-tRNA ligase activity
NXX57_RS07030	COG1609	Transcriptional regulator
NXX57_RS07045	COG0738	Major facilitator superfamily
NXX57_RS07050	COG1063	alcohol dehydrogenase
NXX57_RS07065	COG2211	Major facilitator Superfamily
NXX57_RS07070	COG2385	sporulation resulting in formation of a cellular spore
NXX57_RS07070	COG2247	cell wall binding repeat
NXX57_RS07075	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS07080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX57_RS07135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXX57_RS07145	COG0475	glutathione-regulated potassium exporter activity
NXX57_RS07145	COG0589	response to stress
NXX57_RS07150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXX57_RS07155	COG1136	(ABC) transporter
NXX57_RS07175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXX57_RS07185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXX57_RS07190	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXX57_RS07195	COG0312	modulator of DNA gyrase
NXX57_RS07200	COG0312	modulator of DNA gyrase
NXX57_RS07205	COG1704	LemA family
NXX57_RS07240	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS07250	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX57_RS07260	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS07285	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS07290	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS07320	COG0745	RESPONSE REGULATOR receiver
NXX57_RS07320	COG2205	protein histidine kinase activity
NXX57_RS07320	COG3292	Two component regulator propeller
NXX57_RS07330	COG4771	TonB-dependent receptor
NXX57_RS07375	COG1346	cytolysis
NXX57_RS07380	COG1380	Effector of murein hydrolase LrgA
NXX57_RS07385	COG0280	phosphate acetyltransferase
NXX57_RS07390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXX57_RS07395	COG0463	Glycosyl transferase, family 2
NXX57_RS07395	COG1216	Glycosyl transferase, family 2
NXX57_RS07400	COG2003	Belongs to the UPF0758 family
NXX57_RS07410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX57_RS07415	COG0366	Alpha amylase catalytic
NXX57_RS07430	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX57_RS07435	COG1629	transport
NXX57_RS07435	COG4206	TonB-dependent receptor
NXX57_RS07440	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS07445	COG0366	Alpha amylase catalytic
NXX57_RS07455	COG1785	Belongs to the alkaline phosphatase family
NXX57_RS07460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXX57_RS07465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXX57_RS07470	COG2815	serine threonine protein kinase
NXX57_RS07470	COG0515	serine threonine protein kinase
NXX57_RS07475	COG0564	pseudouridine synthase activity
NXX57_RS07480	COG1181	Belongs to the D-alanine--D-alanine ligase family
NXX57_RS07500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXX57_RS07505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXX57_RS07510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXX57_RS07515	COG0436	Aminotransferase
NXX57_RS07525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXX57_RS07540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXX57_RS07545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXX57_RS07555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXX57_RS07555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXX57_RS07560	COG2890	protein-(glutamine-N5) methyltransferase activity
NXX57_RS07570	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXX57_RS07580	COG0165	Argininosuccinate lyase
NXX57_RS07595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXX57_RS07615	COG3292	Two component regulator propeller
NXX57_RS07615	COG2205	protein histidine kinase activity
NXX57_RS07615	COG3292	Two component regulator propeller
NXX57_RS07615	COG2205	protein histidine kinase activity
NXX57_RS07615	COG0745	RESPONSE REGULATOR receiver
NXX57_RS07615	COG0745	RESPONSE REGULATOR receiver
NXX57_RS07620	COG0471	metal ion transport
NXX57_RS07680	COG4771	TonB-dependent receptor
NXX57_RS07700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXX57_RS07705	COG1917	Cupin 2, conserved barrel domain protein
NXX57_RS07705	COG1396	sequence-specific DNA binding
NXX57_RS07710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXX57_RS07715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXX57_RS07720	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXX57_RS07725	COG0137	argininosuccinate synthase activity
NXX57_RS07735	COG1438	arginine binding
NXX57_RS07740	COG1070	Carbohydrate kinase
NXX57_RS07745	COG4806	L-rhamnose isomerase
NXX57_RS07755	COG0235	Class ii aldolase
NXX57_RS07760	COG1454	alcohol dehydrogenase
NXX57_RS07790	COG0564	pseudouridine synthase activity
NXX57_RS07850	COG3537	Alpha-1,2-mannosidase
NXX57_RS07855	COG2205	protein histidine kinase activity
NXX57_RS07855	COG0745	RESPONSE REGULATOR receiver
NXX57_RS07855	COG3292	Two component regulator propeller
NXX57_RS07865	COG4771	TonB-dependent receptor
NXX57_RS07870	COG0702	epimerase
NXX57_RS07895	COG3119	arylsulfatase activity
NXX57_RS07910	COG3119	arylsulfatase activity
NXX57_RS07915	COG2204	response regulator
NXX57_RS07920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXX57_RS07925	COG0612	Peptidase, M16
NXX57_RS07930	COG0534	Mate efflux family protein
NXX57_RS07935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX57_RS07935	COG2205	protein histidine kinase activity
NXX57_RS07980	COG0488	(ABC) transporter
NXX57_RS07985	COG3590	peptidase
NXX57_RS07990	COG0138	bifunctional purine biosynthesis protein purh
NXX57_RS08025	COG1774	PSP1 C-terminal conserved region
NXX57_RS08030	COG0470	DNA polymerase III
NXX57_RS08035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXX57_RS08045	COG2193	ferroxidase activity
NXX57_RS08055	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX57_RS08055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXX57_RS08120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXX57_RS08125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXX57_RS08130	COG1160	GTP binding
NXX57_RS08145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXX57_RS08150	COG1127	ABC transporter
NXX57_RS08155	COG0724	RNA recognition motif
NXX57_RS08160	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXX57_RS08165	COG0740	serine-type endopeptidase activity
NXX57_RS08170	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXX57_RS08175	COG0514	ATP-dependent DNA helicase (RecQ)
NXX57_RS08180	COG0516	GMP reductase activity
NXX57_RS08180	COG0517	IMP dehydrogenase activity
NXX57_RS08185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXX57_RS08195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXX57_RS08210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXX57_RS08225	COG4771	TonB-dependent receptor
NXX57_RS08245	COG3537	Alpha-1,2-mannosidase
NXX57_RS08280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXX57_RS08290	COG3022	response to hydroperoxide
NXX57_RS08295	COG0110	maltose O-acetyltransferase activity
NXX57_RS08315	COG1187	pseudouridine synthase activity
NXX57_RS08320	COG0017	Asparaginyl-tRNA synthetase
NXX57_RS08330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXX57_RS08335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXX57_RS08340	COG0052	Belongs to the universal ribosomal protein uS2 family
NXX57_RS08345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXX57_RS08360	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXX57_RS08365	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXX57_RS08370	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXX57_RS08385	COG0482	sulfurtransferase activity
NXX57_RS08395	COG1570	exodeoxyribonuclease VII activity
NXX57_RS08405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXX57_RS08415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXX57_RS08420	COG0489	protein tyrosine kinase activity
NXX57_RS08425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX57_RS08460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS08480	COG0714	Associated with various cellular activities
NXX57_RS08485	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXX57_RS08490	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NXX57_RS08495	COG0039	L-malate dehydrogenase activity
NXX57_RS08525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXX57_RS08530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXX57_RS08535	COG0811	peptide transport
NXX57_RS08540	COG0848	biopolymer transport protein
NXX57_RS08555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXX57_RS08560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXX57_RS08565	COG0105	UTP biosynthetic process
NXX57_RS08570	COG0739	heme binding
NXX57_RS08585	COG0149	triose-phosphate isomerase activity
NXX57_RS08595	COG0302	gtp cyclohydrolase
NXX57_RS08600	COG0358	DNA primase activity
NXX57_RS08610	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXX57_RS08615	COG0436	Aminotransferase
NXX57_RS08630	COG0514	ATP-dependent DNA helicase (RecQ)
NXX57_RS08635	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NXX57_RS08635	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NXX57_RS08650	COG0009	L-threonylcarbamoyladenylate synthase
NXX57_RS08660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXX57_RS08665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXX57_RS08670	COG2333	competence protein COMEC
NXX57_RS08670	COG0658	competence protein
NXX57_RS08675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXX57_RS08685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXX57_RS08695	COG4771	TonB-dependent receptor
NXX57_RS08700	COG0561	phosphatase activity
NXX57_RS08720	COG3292	Two component regulator propeller
NXX57_RS08720	COG2205	protein histidine kinase activity
NXX57_RS08720	COG0745	RESPONSE REGULATOR receiver
NXX57_RS08725	COG4771	TonB-dependent receptor
NXX57_RS08745	COG3537	Alpha-1,2-mannosidase
NXX57_RS08750	COG3537	Alpha-1,2-mannosidase
NXX57_RS08760	COG3537	Alpha-1,2-mannosidase
NXX57_RS08765	COG3279	Response regulator of the LytR AlgR family
NXX57_RS08770	COG3275	phosphorelay sensor kinase activity
NXX57_RS08775	COG1566	PFAM secretion protein HlyD family protein
NXX57_RS08790	COG0386	Belongs to the glutathione peroxidase family
NXX57_RS08795	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NXX57_RS08800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXX57_RS08815	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXX57_RS08830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXX57_RS08835	COG0742	ribosomal rna small subunit methyltransferase
NXX57_RS08850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXX57_RS08855	COG4771	TonB-dependent receptor
NXX57_RS08890	COG3537	Alpha-1,2-mannosidase
NXX57_RS08895	COG3537	Alpha-1,2-mannosidase
NXX57_RS08915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXX57_RS08920	COG0739	heme binding
NXX57_RS08930	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXX57_RS08935	COG0741	lytic transglycosylase activity
NXX57_RS08935	COG1388	LysM domain
NXX57_RS08945	COG1475	DNA binding
NXX57_RS08950	COG1192	Involved in chromosome partitioning
NXX57_RS08955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXX57_RS08960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX57_RS08970	COG4589	Belongs to the CDS family
NXX57_RS08975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXX57_RS08980	COG0799	negative regulation of ribosome biogenesis
NXX57_RS08990	COG0702	epimerase
NXX57_RS08995	COG1629	transport
NXX57_RS08995	COG4206	TonB-dependent receptor
NXX57_RS09000	COG3291	Pkd domain containing protein
NXX57_RS09000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS09010	COG1196	nuclear chromosome segregation
NXX57_RS09015	COG2239	Acts as a magnesium transporter
NXX57_RS09020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXX57_RS09030	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX57_RS09065	COG1119	ATPase activity
NXX57_RS09075	COG0668	transmembrane transport
NXX57_RS09080	COG0662	Cupin 2, conserved barrel domain protein
NXX57_RS09080	COG2207	Transcriptional regulator
NXX57_RS09105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX57_RS09110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXX57_RS09115	COG0713	ATP synthesis coupled electron transport
NXX57_RS09130	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXX57_RS09135	COG0649	NAD binding
NXX57_RS09135	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX57_RS09140	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX57_RS09145	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX57_RS09175	COG3250	beta-galactosidase activity
NXX57_RS09185	COG3250	beta-galactosidase activity
NXX57_RS09195	COG2755	lipolytic protein G-D-S-L family
NXX57_RS09195	COG0657	acetylesterase activity
NXX57_RS09210	COG4771	TonB-dependent receptor
NXX57_RS09230	COG0702	epimerase
NXX57_RS09250	COG4771	TonB-dependent receptor
NXX57_RS09255	COG0702	epimerase
NXX57_RS09260	COG4206	TonB-dependent receptor
NXX57_RS09260	COG1629	transport
NXX57_RS09275	COG3537	Alpha-1,2-mannosidase
NXX57_RS09295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXX57_RS09300	COG0569	domain protein
NXX57_RS09305	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXX57_RS09315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXX57_RS09320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXX57_RS09325	COG0805	protein transport
NXX57_RS09335	COG2271	Major facilitator Superfamily
NXX57_RS09340	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXX57_RS09345	COG3775	system Galactitol-specific IIC component
NXX57_RS09360	COG2755	lipolytic protein G-D-S-L family
NXX57_RS09365	COG3292	Two component regulator propeller
NXX57_RS09365	COG2205	protein histidine kinase activity
NXX57_RS09365	COG0745	RESPONSE REGULATOR receiver
NXX57_RS09375	COG0702	epimerase
NXX57_RS09380	COG1629	transport
NXX57_RS09400	COG3279	Response regulator of the LytR AlgR family
NXX57_RS09415	COG1629	transport
NXX57_RS09415	COG4206	TonB-dependent receptor
NXX57_RS09430	COG0745	RESPONSE REGULATOR receiver
NXX57_RS09430	COG2205	protein histidine kinase activity
NXX57_RS09430	COG3292	Two component regulator propeller
NXX57_RS09435	COG1242	4 iron, 4 sulfur cluster binding
NXX57_RS09445	COG0363	glucosamine-6-phosphate deaminase activity
NXX57_RS09450	COG0009	L-threonylcarbamoyladenylate synthase
NXX57_RS09460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXX57_RS09465	COG0561	phosphatase activity
NXX57_RS09490	COG4771	TonB-dependent receptor
NXX57_RS09505	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXX57_RS09510	COG1408	metallophosphoesterase
NXX57_RS09535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXX57_RS09560	COG2755	lipolytic protein G-D-S-L family
NXX57_RS09590	COG3401	FG-GAP repeat protein
NXX57_RS09595	COG3250	beta-galactosidase activity
NXX57_RS09605	COG3250	beta-galactosidase activity
NXX57_RS09615	COG3345	alpha-galactosidase
NXX57_RS09630	COG3250	beta-galactosidase activity
NXX57_RS09695	COG4771	TonB-dependent receptor
NXX57_RS09710	COG0702	epimerase
NXX57_RS09715	COG4771	TonB-dependent receptor
NXX57_RS09735	COG4771	TonB-dependent receptor
NXX57_RS09740	COG0702	epimerase
NXX57_RS09755	COG4771	TonB-dependent receptor
NXX57_RS09780	COG2755	lipolytic protein G-D-S-L family
NXX57_RS09790	COG3401	FG-GAP repeat protein
NXX57_RS09800	COG3254	rhamnose metabolic process
NXX57_RS09805	COG0745	RESPONSE REGULATOR receiver
NXX57_RS09805	COG2205	protein histidine kinase activity
NXX57_RS09805	COG3292	Two component regulator propeller
NXX57_RS09805	COG0745	RESPONSE REGULATOR receiver
NXX57_RS09805	COG2205	protein histidine kinase activity
NXX57_RS09805	COG3292	Two component regulator propeller
NXX57_RS09820	COG3250	beta-galactosidase activity
NXX57_RS09825	COG0745	RESPONSE REGULATOR receiver
NXX57_RS09825	COG3292	Two component regulator propeller
NXX57_RS09825	COG2205	protein histidine kinase activity
NXX57_RS09835	COG0546	phosphoglycolate phosphatase activity
NXX57_RS09855	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXX57_RS09865	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXX57_RS09875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXX57_RS09880	COG1506	peptidase
NXX57_RS09880	COG0823	Involved in the tonB-independent uptake of proteins
NXX57_RS09900	COG5433	transposase activity
NXX57_RS09930	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXX57_RS09945	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXX57_RS09945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXX57_RS09950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX57_RS09955	COG1078	dGTPase activity
NXX57_RS09960	COG0284	orotidine-5'-phosphate decarboxylase activity
NXX57_RS09965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXX57_RS09975	COG1704	LemA family
NXX57_RS09995	COG2226	methyltransferase
NXX57_RS10000	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXX57_RS10005	COG1702	phosphate starvation-inducible protein PhoH
NXX57_RS10025	COG2268	Band 7 protein
NXX57_RS10120	COG0745	RESPONSE REGULATOR receiver
NXX57_RS10120	COG2205	protein histidine kinase activity
NXX57_RS10120	COG3292	Two component regulator propeller
NXX57_RS10125	COG0101	tRNA pseudouridine synthase activity
NXX57_RS10145	COG3250	beta-galactosidase activity
NXX57_RS10150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXX57_RS10155	COG0673	inositol 2-dehydrogenase activity
NXX57_RS10195	COG5434	Belongs to the glycosyl hydrolase 28 family
NXX57_RS10200	COG5434	Belongs to the glycosyl hydrolase 28 family
NXX57_RS10205	COG0673	inositol 2-dehydrogenase activity
NXX57_RS10220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXX57_RS10230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXX57_RS10240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NXX57_RS10245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXX57_RS10250	COG0793	Belongs to the peptidase S41A family
NXX57_RS10255	COG2131	deaminase
NXX57_RS10265	COG0339	signal peptide processing
NXX57_RS10275	COG1970	mechanosensitive ion channel activity
NXX57_RS10280	COG0519	Catalyzes the synthesis of GMP from XMP
NXX57_RS10280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXX57_RS10295	COG4771	TonB-dependent receptor
NXX57_RS10350	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS10355	COG0463	Glycosyl transferase, family 2
NXX57_RS10430	COG4771	TonB-dependent receptor
NXX57_RS10465	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS10480	COG0297	glycogen (starch) synthase activity
NXX57_RS10485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXX57_RS10490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXX57_RS10495	COG0543	2 iron, 2 sulfur cluster binding
NXX57_RS10505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXX57_RS10510	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXX57_RS10515	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXX57_RS10530	COG0791	NLP P60 protein
NXX57_RS10545	COG0612	Peptidase, M16
NXX57_RS10550	COG0612	Peptidase, M16
NXX57_RS10555	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXX57_RS10560	COG1597	lipid kinase activity
NXX57_RS10565	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXX57_RS10580	COG1136	(ABC) transporter
NXX57_RS10600	COG2211	Major facilitator Superfamily
NXX57_RS10605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXX57_RS10620	COG1674	ftsk spoiiie
NXX57_RS10630	COG0492	ferredoxin-NADP+ reductase activity
NXX57_RS10635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS10665	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX57_RS10665	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX57_RS10675	COG1234	tRNA 3'-trailer cleavage
NXX57_RS10695	COG3956	TIGRFAM MazG family protein
NXX57_RS10710	COG0525	valine-tRNA ligase activity
NXX57_RS10715	COG0784	Response regulator, receiver
NXX57_RS10715	COG2205	protein histidine kinase activity
NXX57_RS10730	COG4206	TonB-dependent receptor
NXX57_RS10730	COG1629	transport
NXX57_RS10755	COG0653	protein targeting
NXX57_RS10760	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXX57_RS10770	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXX57_RS10790	COG1253	flavin adenine dinucleotide binding
NXX57_RS10800	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXX57_RS10810	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXX57_RS10815	COG2204	response regulator
NXX57_RS10855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXX57_RS10855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXX57_RS10875	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXX57_RS10880	COG0563	adenylate kinase activity
NXX57_RS10885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXX57_RS10890	COG1496	oxidoreductase activity
NXX57_RS10905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS10910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS10920	COG0477	Major facilitator Superfamily
NXX57_RS10920	COG2814	Major facilitator Superfamily
NXX57_RS10925	COG0457	Tetratricopeptide repeat
NXX57_RS10930	COG2706	6-phosphogluconolactonase activity
NXX57_RS10955	COG1629	transport
NXX57_RS10955	COG4206	TonB-dependent receptor
NXX57_RS11020	COG3142	Participates in the control of copper homeostasis
NXX57_RS11025	COG1418	mRNA catabolic process
NXX57_RS11055	COG1070	Carbohydrate kinase
NXX57_RS11060	COG1063	alcohol dehydrogenase
NXX57_RS11065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXX57_RS11095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXX57_RS11095	COG1333	cytochrome c biogenesis protein
NXX57_RS11135	COG0673	inositol 2-dehydrogenase activity
NXX57_RS11145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXX57_RS11150	COG2832	Protein of unknown function (DUF454)
NXX57_RS11160	COG0602	queuosine metabolic process
NXX57_RS11165	COG0247	lactate metabolic process
NXX57_RS11170	COG1139	Iron-sulfur cluster binding protein
NXX57_RS11180	COG0351	phosphomethylpyrimidine kinase
NXX57_RS11205	COG4589	Belongs to the CDS family
NXX57_RS11215	COG2304	oxidoreductase activity
NXX57_RS11225	COG1393	Belongs to the ArsC family
NXX57_RS11235	COG4206	TonB-dependent receptor
NXX57_RS11235	COG1629	transport
NXX57_RS11250	COG2233	PERMEase
NXX57_RS11255	COG1509	lysine 2,3-aminomutase activity
NXX57_RS11265	COG1115	amino acid carrier protein
NXX57_RS11305	COG1285	pathogenesis
NXX57_RS11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXX57_RS11320	COG0741	lytic transglycosylase activity
NXX57_RS11320	COG1388	LysM domain
NXX57_RS11350	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXX57_RS11365	COG0534	Mate efflux family protein
NXX57_RS11375	COG0564	pseudouridine synthase activity
NXX57_RS11400	COG0346	lactoylglutathione lyase activity
NXX57_RS11415	COG2207	Transcriptional regulator
NXX57_RS11415	COG0662	Cupin 2, conserved barrel domain protein
NXX57_RS11420	COG0653	protein targeting
NXX57_RS11495	COG1111	helicase
NXX57_RS11495	COG1205	dead DEAH box helicase
NXX57_RS11495	COG1111	helicase
NXX57_RS11495	COG1205	dead DEAH box helicase
NXX57_RS11585	COG4974	Belongs to the 'phage' integrase family
NXX57_RS11620	COG1910	domain protein
NXX57_RS11645	COG4974	Belongs to the 'phage' integrase family
NXX57_RS11655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXX57_RS11670	COG2201	protein-glutamate methylesterase activity
NXX57_RS11675	COG2910	NAD(P)H-binding
NXX57_RS11685	COG4864	UPF0365 protein
NXX57_RS11700	COG0037	tRNA processing
NXX57_RS11710	COG1477	protein flavinylation
NXX57_RS11715	COG1971	Probably functions as a manganese efflux pump
NXX57_RS11730	COG0463	Glycosyl transferase, family 2
NXX57_RS11755	COG1595	DNA-templated transcription, initiation
NXX57_RS11760	COG0148	phosphopyruvate hydratase activity
NXX57_RS11770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXX57_RS11785	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS11790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXX57_RS11795	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX57_RS11800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXX57_RS11805	COG4651	solute:proton antiporter activity
NXX57_RS11805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXX57_RS11815	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXX57_RS11820	COG0193	aminoacyl-tRNA hydrolase activity
NXX57_RS11825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXX57_RS11840	COG1862	Preprotein translocase
NXX57_RS11850	COG0237	dephospho-CoA kinase activity
NXX57_RS11865	COG0542	response to heat
NXX57_RS11875	COG0583	DNA-binding transcription factor activity
NXX57_RS11885	COG2855	membrane
NXX57_RS11890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXX57_RS11895	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXX57_RS11915	COG0443	Heat shock 70 kDa protein
NXX57_RS12010	COG0306	phosphate transporter
NXX57_RS12020	COG0586	Pfam SNARE associated Golgi protein
NXX57_RS12075	COG0038	chloride channel
NXX57_RS12080	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXX57_RS12105	COG3119	arylsulfatase activity
NXX57_RS12115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX57_RS12120	COG0702	epimerase
NXX57_RS12125	COG4771	TonB-dependent receptor
NXX57_RS12135	COG5434	Belongs to the glycosyl hydrolase 28 family
NXX57_RS12140	COG0745	RESPONSE REGULATOR receiver
NXX57_RS12140	COG2205	protein histidine kinase activity
NXX57_RS12140	COG3292	Two component regulator propeller
NXX57_RS12145	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXX57_RS12150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXX57_RS12160	COG3250	beta-galactosidase activity
NXX57_RS12175	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX57_RS12180	COG1629	transport
NXX57_RS12180	COG4206	TonB-dependent receptor
NXX57_RS12190	COG5002	protein histidine kinase activity
NXX57_RS12215	COG1760	l-serine dehydratase
NXX57_RS12220	COG0598	Magnesium transport protein CorA
NXX57_RS12225	COG1193	negative regulation of DNA recombination
NXX57_RS12235	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS12250	COG3250	beta-galactosidase activity
NXX57_RS12260	COG0668	transmembrane transport
NXX57_RS12265	COG1523	belongs to the glycosyl hydrolase 13 family
NXX57_RS12275	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXX57_RS12285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS12295	COG1538	Outer membrane efflux protein
NXX57_RS12305	COG0456	acetyltransferase
NXX57_RS12315	COG3189	MarR family transcriptional regulator
NXX57_RS12320	COG0561	phosphatase activity
NXX57_RS12325	COG1169	isochorismate synthase
NXX57_RS12330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXX57_RS12335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXX57_RS12340	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS12345	COG0318	PFAM AMP-dependent synthetase and ligase
NXX57_RS12360	COG1629	transport
NXX57_RS12360	COG4206	TonB-dependent receptor
NXX57_RS12400	COG0783	Belongs to the Dps family
NXX57_RS12405	COG0583	DNA-binding transcription factor activity
NXX57_RS12415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXX57_RS12445	COG4771	TonB-dependent receptor
NXX57_RS12450	COG0561	phosphatase activity
NXX57_RS12525	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS12530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXX57_RS12535	COG1882	Formate acetyltransferase
NXX57_RS12545	COG4974	Belongs to the 'phage' integrase family
NXX57_RS12550	COG4974	Belongs to the 'phage' integrase family
NXX57_RS12560	COG2003	Belongs to the UPF0758 family
NXX57_RS12670	COG0358	DNA primase activity
NXX57_RS12750	COG3344	reverse transcriptase
NXX57_RS12765	COG0464	growth
NXX57_RS12790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXX57_RS12790	COG0551	DNA topoisomerase type I activity
NXX57_RS12835	COG4974	Belongs to the 'phage' integrase family
NXX57_RS12985	COG4974	Belongs to the 'phage' integrase family
NXX57_RS12990	COG4974	Belongs to the 'phage' integrase family
NXX57_RS13080	COG1475	DNA binding
NXX57_RS13130	COG1373	ATPase (AAA superfamily
NXX57_RS13135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXX57_RS13140	COG0739	heme binding
NXX57_RS13140	COG1196	nuclear chromosome segregation
NXX57_RS13140	COG0741	lytic transglycosylase activity
NXX57_RS13235	COG2198	Histidine kinase
NXX57_RS13235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX57_RS13235	COG0784	Response regulator, receiver
NXX57_RS13235	COG2205	protein histidine kinase activity
NXX57_RS13245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXX57_RS13250	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS13270	COG2205	protein histidine kinase activity
NXX57_RS13270	COG2198	Histidine kinase
NXX57_RS13270	COG0784	Response regulator, receiver
NXX57_RS13270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX57_RS13320	COG1192	Involved in chromosome partitioning
NXX57_RS13415	COG0798	PFAM Bile acid sodium symporter
NXX57_RS13420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXX57_RS13460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXX57_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS13510	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS13515	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXX57_RS13540	COG2205	protein histidine kinase activity
NXX57_RS13540	COG3292	Two component regulator propeller
NXX57_RS13540	COG0745	RESPONSE REGULATOR receiver
NXX57_RS13540	COG0745	RESPONSE REGULATOR receiver
NXX57_RS13540	COG2205	protein histidine kinase activity
NXX57_RS13540	COG3292	Two component regulator propeller
NXX57_RS13545	COG1595	DNA-templated transcription, initiation
NXX57_RS13550	COG4206	TonB-dependent receptor
NXX57_RS13550	COG1629	transport
NXX57_RS13575	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX57_RS13585	COG1253	flavin adenine dinucleotide binding
NXX57_RS13590	COG0501	Belongs to the peptidase M48B family
NXX57_RS13615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX57_RS13620	COG0482	sulfurtransferase activity
NXX57_RS13625	COG2197	response regulator
NXX57_RS13635	COG1757	Na H antiporter
NXX57_RS13650	COG2814	Major facilitator Superfamily
NXX57_RS13655	COG4953	penicillin-binding protein 1C
NXX57_RS13660	COG2373	Large extracellular alpha-helical protein
NXX57_RS13665	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX57_RS13765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXX57_RS13770	COG0646	methionine synthase
NXX57_RS13770	COG1410	methionine synthase
NXX57_RS13775	COG0778	Nitroreductase
NXX57_RS13780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX57_RS13790	COG0572	uridine kinase
NXX57_RS13800	COG4232	protein-disulfide reductase activity
NXX57_RS13805	COG1741	Belongs to the pirin family
NXX57_RS13820	COG1629	transport
NXX57_RS13825	COG0702	epimerase
NXX57_RS13850	COG2271	Major facilitator Superfamily
NXX57_RS13870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXX57_RS13875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXX57_RS13880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXX57_RS13885	COG0131	Imidazoleglycerol-phosphate dehydratase
NXX57_RS13895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXX57_RS13895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX57_RS13900	COG4771	TonB-dependent receptor
NXX57_RS13930	COG1404	Belongs to the peptidase S8 family
NXX57_RS13950	COG1773	rubredoxin
NXX57_RS13950	COG1592	Rubrerythrin
NXX57_RS13980	COG3591	Belongs to the peptidase S1B family
NXX57_RS13985	COG3591	Belongs to the peptidase S1B family
NXX57_RS13990	COG0641	radical SAM
NXX57_RS14020	COG0420	3'-5' exonuclease activity
NXX57_RS14030	COG1408	metallophosphoesterase
NXX57_RS14045	COG1410	methionine synthase
NXX57_RS14045	COG0646	methionine synthase
NXX57_RS14055	COG0463	Glycosyl transferase, family 2
NXX57_RS14060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NXX57_RS14070	COG1032	radical SAM domain protein
NXX57_RS14090	COG0363	glucosamine-6-phosphate deaminase activity
NXX57_RS14095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX57_RS14130	COG3292	Two component regulator propeller
NXX57_RS14130	COG2205	protein histidine kinase activity
NXX57_RS14130	COG0745	RESPONSE REGULATOR receiver
NXX57_RS14135	COG1629	transport
NXX57_RS14145	COG0702	epimerase
NXX57_RS14165	COG4771	TonB-dependent receptor
NXX57_RS14220	COG0811	peptide transport
NXX57_RS14225	COG0848	biopolymer transport protein
NXX57_RS14280	COG1131	(ABC) transporter
NXX57_RS14315	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXX57_RS14355	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXX57_RS14360	COG0022	dehydrogenase e1 component
NXX57_RS14370	COG2264	protein methyltransferase activity
NXX57_RS14390	COG0590	tRNA wobble adenosine to inosine editing
NXX57_RS14395	COG0673	inositol 2-dehydrogenase activity
NXX57_RS14420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXX57_RS14465	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXX57_RS14480	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX57_RS14485	COG5012	cobalamin binding
NXX57_RS14505	COG0698	ribose 5-phosphate isomerase
NXX57_RS14510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NXX57_RS14525	COG1070	Carbohydrate kinase
NXX57_RS14530	COG2160	L-arabinose isomerase activity
NXX57_RS14560	COG0702	epimerase
NXX57_RS14565	COG4206	TonB-dependent receptor
NXX57_RS14565	COG1629	transport
NXX57_RS14575	COG4206	TonB-dependent receptor
NXX57_RS14575	COG1629	transport
NXX57_RS14585	COG0745	RESPONSE REGULATOR receiver
NXX57_RS14585	COG2205	protein histidine kinase activity
NXX57_RS14585	COG3292	Two component regulator propeller
NXX57_RS14590	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS14600	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS14605	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXX57_RS14620	COG1482	cell wall glycoprotein biosynthetic process
NXX57_RS14625	COG4974	Belongs to the 'phage' integrase family
NXX57_RS14655	COG1086	Polysaccharide biosynthesis protein
NXX57_RS14685	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS14710	COG0297	glycogen (starch) synthase activity
NXX57_RS14710	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS14725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX57_RS14755	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS14795	COG4221	oxidoreductase activity
NXX57_RS14805	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXX57_RS14810	COG0471	metal ion transport
NXX57_RS14810	COG3273	potassium ion transport
NXX57_RS14815	COG0529	Catalyzes the synthesis of activated sulfate
NXX57_RS14820	COG0175	sulfate reduction
NXX57_RS14825	COG2895	sulfate adenylyltransferase (ATP) activity
NXX57_RS14845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXX57_RS14850	COG0242	peptide deformylase activity
NXX57_RS14860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXX57_RS14865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXX57_RS14870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXX57_RS14875	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXX57_RS14885	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXX57_RS14890	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXX57_RS14895	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXX57_RS14895	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXX57_RS14895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NXX57_RS14895	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXX57_RS14905	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXX57_RS14925	COG2815	serine threonine protein kinase
NXX57_RS14925	COG0515	serine threonine protein kinase
NXX57_RS15045	COG3620	sequence-specific DNA binding
NXX57_RS15150	COG1396	sequence-specific DNA binding
NXX57_RS15205	COG5410	chromosome segregation
NXX57_RS15375	COG3561	AntA/AntB antirepressor
NXX57_RS15500	COG1940	carbohydrate kinase activity
NXX57_RS15505	COG2081	HI0933 family
NXX57_RS15515	COG2814	Major facilitator Superfamily
NXX57_RS15530	COG4771	TonB-dependent receptor
NXX57_RS15550	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS15560	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS15570	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS15575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS15595	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS15615	COG0702	epimerase
NXX57_RS15620	COG4771	TonB-dependent receptor
NXX57_RS15695	COG1629	transport
NXX57_RS15720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS15725	COG0657	acetylesterase activity
NXX57_RS15725	COG2755	lipolytic protein G-D-S-L family
NXX57_RS15735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS15740	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS15745	COG3250	beta-galactosidase activity
NXX57_RS15765	COG1091	dTDP-4-dehydrorhamnose reductase activity
NXX57_RS15800	COG1216	Glycosyl transferase, family 2
NXX57_RS15805	COG1216	Glycosyl transferase, family 2
NXX57_RS15825	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS15845	COG1629	transport
NXX57_RS15855	COG0484	heat shock protein binding
NXX57_RS15860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXX57_RS15865	COG0488	(ABC) transporter
NXX57_RS15880	COG2183	response to ionizing radiation
NXX57_RS15885	COG2205	protein histidine kinase activity
NXX57_RS15885	COG2202	Pas domain
NXX57_RS15930	COG0490	domain, Protein
NXX57_RS15930	COG2985	domain, Protein
NXX57_RS15935	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXX57_RS15945	COG0318	PFAM AMP-dependent synthetase and ligase
NXX57_RS15950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX57_RS15955	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXX57_RS15960	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NXX57_RS15965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXX57_RS15975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXX57_RS15985	COG2837	iron assimilation
NXX57_RS15990	COG2135	peptidase activity
NXX57_RS15995	COG3279	Response regulator of the LytR AlgR family
NXX57_RS16005	COG0577	efflux transmembrane transporter activity
NXX57_RS16005	COG1136	(ABC) transporter
NXX57_RS16010	COG1136	(ABC) transporter
NXX57_RS16015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS16040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXX57_RS16050	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXX57_RS16075	COG0501	Belongs to the peptidase M48B family
NXX57_RS16080	COG1704	LemA family
NXX57_RS16095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXX57_RS16100	COG2885	chlorophyll binding
NXX57_RS16105	COG0534	Mate efflux family protein
NXX57_RS16110	COG2755	lipolytic protein G-D-S-L family
NXX57_RS16110	COG0657	acetylesterase activity
NXX57_RS16120	COG1162	GTPase activity
NXX57_RS16140	COG0488	(ABC) transporter
NXX57_RS16170	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS16175	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS16180	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS16185	COG1442	glycosyl transferase family 8
NXX57_RS16195	COG2244	polysaccharide biosynthetic process
NXX57_RS16200	COG1442	glycosyl transferase family 8
NXX57_RS16200	COG1216	Glycosyl transferase, family 2
NXX57_RS16245	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS16255	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS16290	COG1805	sodium ion transport
NXX57_RS16295	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXX57_RS16305	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXX57_RS16310	COG2871	sodium ion transport
NXX57_RS16315	COG0513	Belongs to the DEAD box helicase family
NXX57_RS16320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXX57_RS16335	COG1739	Uncharacterized protein family UPF0029
NXX57_RS16350	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXX57_RS16350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXX57_RS16355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXX57_RS16360	COG0357	Ribosomal RNA small subunit methyltransferase G
NXX57_RS16405	COG2217	Heavy metal translocating P-type atpase
NXX57_RS16415	COG0321	lipoyl(octanoyl) transferase activity
NXX57_RS16450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXX57_RS16460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXX57_RS16475	COG1678	Uncharacterized ACR, COG1678
NXX57_RS16495	COG3275	phosphorelay sensor kinase activity
NXX57_RS16525	COG3969	phosphoadenosine phosphosulfate
NXX57_RS16530	COG1475	DNA binding
NXX57_RS16595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXX57_RS16615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS16640	COG4206	TonB-dependent receptor
NXX57_RS16640	COG1629	transport
NXX57_RS16670	COG4206	TonB-dependent receptor
NXX57_RS16670	COG1629	transport
NXX57_RS16705	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXX57_RS16725	COG1629	transport
NXX57_RS16725	COG4206	TonB-dependent receptor
NXX57_RS16730	COG0702	epimerase
NXX57_RS16755	COG3408	Glycogen debranching enzyme
NXX57_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS16785	COG3408	Glycogen debranching enzyme
NXX57_RS16795	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX57_RS16805	COG0167	dihydroorotate dehydrogenase activity
NXX57_RS16810	COG0657	acetylesterase activity
NXX57_RS16810	COG2755	lipolytic protein G-D-S-L family
NXX57_RS16880	COG0784	Response regulator, receiver
NXX57_RS16880	COG2205	protein histidine kinase activity
NXX57_RS16890	COG3250	beta-galactosidase activity
NXX57_RS16895	COG0745	RESPONSE REGULATOR receiver
NXX57_RS16900	COG5002	protein histidine kinase activity
NXX57_RS16985	COG1538	Outer membrane efflux protein
NXX57_RS17005	COG3250	beta-galactosidase activity
NXX57_RS17010	COG0745	RESPONSE REGULATOR receiver
NXX57_RS17010	COG2205	protein histidine kinase activity
NXX57_RS17010	COG3292	Two component regulator propeller
NXX57_RS17040	COG2966	Psort location CytoplasmicMembrane, score
NXX57_RS17055	COG0300	oxidoreductase activity
NXX57_RS17065	COG1011	Hydrolase
NXX57_RS17085	COG1595	DNA-templated transcription, initiation
NXX57_RS17130	COG3292	Two component regulator propeller
NXX57_RS17130	COG2205	protein histidine kinase activity
NXX57_RS17130	COG2205	protein histidine kinase activity
NXX57_RS17130	COG3292	Two component regulator propeller
NXX57_RS17130	COG0745	RESPONSE REGULATOR receiver
NXX57_RS17130	COG0745	RESPONSE REGULATOR receiver
NXX57_RS17145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS17160	COG0442	prolyl-tRNA aminoacylation
NXX57_RS17165	COG0745	RESPONSE REGULATOR receiver
NXX57_RS17170	COG2205	protein histidine kinase activity
NXX57_RS17205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXX57_RS17215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXX57_RS17220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXX57_RS17230	COG0552	protein localization to endoplasmic reticulum
NXX57_RS17235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX57_RS17240	COG0776	regulation of translation
NXX57_RS17245	COG0776	regulation of translation
NXX57_RS17250	COG0714	Associated with various cellular activities
NXX57_RS17265	COG2304	oxidoreductase activity
NXX57_RS17315	COG0326	Molecular chaperone. Has ATPase activity
NXX57_RS17330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXX57_RS17335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXX57_RS17340	COG0336	Belongs to the RNA methyltransferase TrmD family
NXX57_RS17345	COG0167	dihydroorotate dehydrogenase activity
NXX57_RS17350	COG0543	2 iron, 2 sulfur cluster binding
NXX57_RS17365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXX57_RS17400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXX57_RS17420	COG1132	(ABC) transporter
NXX57_RS17450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXX57_RS17455	COG1597	lipid kinase activity
NXX57_RS17460	COG0156	8-amino-7-oxononanoate synthase activity
NXX57_RS17475	COG4771	TonB-dependent receptor
NXX57_RS17515	COG1136	(ABC) transporter
NXX57_RS17540	COG3852	Histidine kinase
NXX57_RS17550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXX57_RS17625	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXX57_RS17630	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXX57_RS17650	COG3830	Belongs to the UPF0237 family
NXX57_RS17650	COG0560	Phosphoserine phosphatase
NXX57_RS17655	COG0513	Belongs to the DEAD box helicase family
NXX57_RS17685	COG0246	Mannitol dehydrogenase
NXX57_RS17695	COG1904	glucuronate isomerase
NXX57_RS17710	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXX57_RS17735	COG3015	lipoprotein NlpE involved in copper resistance
NXX57_RS17765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXX57_RS17780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXX57_RS17790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXX57_RS17800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX57_RS17800	COG3153	acetyltransferase
NXX57_RS17805	COG0477	Major facilitator Superfamily
NXX57_RS17805	COG2814	Major facilitator Superfamily
NXX57_RS17810	COG2115	Belongs to the xylose isomerase family
NXX57_RS17825	COG0351	phosphomethylpyrimidine kinase
NXX57_RS17830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXX57_RS17835	COG0045	succinate-CoA ligase (ADP-forming) activity
NXX57_RS17840	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXX57_RS17860	COG0724	RNA recognition motif
NXX57_RS17885	COG2326	polyphosphate kinase activity
NXX57_RS17895	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXX57_RS17920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXX57_RS17935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXX57_RS17940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXX57_RS17950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX57_RS18030	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NXX57_RS18200	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS18220	COG2205	protein histidine kinase activity
NXX57_RS18220	COG0745	RESPONSE REGULATOR receiver
NXX57_RS18220	COG3292	Two component regulator propeller
NXX57_RS18280	COG2244	polysaccharide biosynthetic process
NXX57_RS18305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXX57_RS18325	COG3958	Transketolase
NXX57_RS18330	COG3959	Transketolase, thiamine diphosphate binding domain
NXX57_RS18335	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS18340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXX57_RS18355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXX57_RS18375	COG0535	radical SAM domain protein
NXX57_RS18410	COG3250	beta-galactosidase activity
NXX57_RS18415	COG3119	arylsulfatase activity
NXX57_RS18425	COG1629	transport
NXX57_RS18425	COG4206	TonB-dependent receptor
NXX57_RS18450	COG2205	protein histidine kinase activity
NXX57_RS18455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXX57_RS18470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXX57_RS18485	COG0540	Belongs to the ATCase OTCase family
NXX57_RS18490	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXX57_RS18505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXX57_RS18510	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXX57_RS18515	COG2985	domain, Protein
NXX57_RS18555	COG2207	Transcriptional regulator
NXX57_RS18580	COG2431	L-lysine efflux transmembrane transporter activity
NXX57_RS18585	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXX57_RS18595	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXX57_RS18600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXX57_RS18605	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX57_RS18610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXX57_RS18615	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX57_RS18620	COG0356	it plays a direct role in the translocation of protons across the membrane
NXX57_RS18630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXX57_RS18635	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXX57_RS18660	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS18675	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXX57_RS18695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXX57_RS18705	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXX57_RS18715	COG0534	Mate efflux family protein
NXX57_RS18725	COG1136	(ABC) transporter
NXX57_RS18760	COG1151	hydroxylamine reductase activity
NXX57_RS18765	COG2233	PERMEase
NXX57_RS18770	COG3263	regulation of cellular component size
NXX57_RS18775	COG0318	PFAM AMP-dependent synthetase and ligase
NXX57_RS18780	COG1082	Xylose isomerase domain protein TIM barrel
NXX57_RS18785	COG0745	RESPONSE REGULATOR receiver
NXX57_RS18790	COG5002	protein histidine kinase activity
NXX57_RS18810	COG3118	belongs to the thioredoxin family
NXX57_RS18815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXX57_RS18860	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXX57_RS18910	COG0681	Belongs to the peptidase S26 family
NXX57_RS19000	COG0352	thiamine-phosphate diphosphorylase activity
NXX57_RS19005	COG2022	thiamine diphosphate biosynthetic process
NXX57_RS19010	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXX57_RS19015	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXX57_RS19020	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXX57_RS19025	COG0352	thiamine-phosphate diphosphorylase activity
NXX57_RS19040	COG0574	Belongs to the PEP-utilizing enzyme family
NXX57_RS19040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXX57_RS19045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXX57_RS19050	COG0564	pseudouridine synthase activity
NXX57_RS19070	COG0024	Methionine aminopeptidase
NXX57_RS19090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXX57_RS19100	COG0481	GTPase activity
NXX57_RS19115	COG0708	Exodeoxyribonuclease III
NXX57_RS19130	COG0217	transcriptional regulatory protein
NXX57_RS19135	COG0072	phenylalanine-tRNA ligase activity
NXX57_RS19135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX57_RS19140	COG0305	Participates in initiation and elongation during chromosome replication
NXX57_RS19145	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXX57_RS19150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXX57_RS19155	COG4657	Part of a membrane complex involved in electron transport
NXX57_RS19160	COG4660	Part of a membrane complex involved in electron transport
NXX57_RS19165	COG4659	FMN binding
NXX57_RS19170	COG4658	electron transport chain
NXX57_RS19175	COG4656	Part of a membrane complex involved in electron transport
NXX57_RS19215	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXX57_RS19235	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS19240	COG1045	serine acetyltransferase
NXX57_RS19265	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXX57_RS19270	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NXX57_RS19325	COG0504	CTP synthase activity
NXX57_RS19330	COG0706	membrane insertase activity
NXX57_RS19335	COG0534	Mate efflux family protein
NXX57_RS19340	COG0823	Involved in the tonB-independent uptake of proteins
NXX57_RS19340	COG1506	peptidase
NXX57_RS19360	COG1983	PspC domain protein
NXX57_RS19365	COG1695	Transcriptional regulator
NXX57_RS19375	COG3104	oligopeptide transport
NXX57_RS19380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXX57_RS19390	COG1388	LysM domain
NXX57_RS19390	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS19420	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXX57_RS19425	COG0556	nucleotide-excision repair
NXX57_RS19440	COG2949	membrane
NXX57_RS19445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXX57_RS19460	COG0842	Transport permease protein
NXX57_RS19465	COG1131	(ABC) transporter
NXX57_RS19480	COG2207	Transcriptional regulator
NXX57_RS19480	COG1917	Cupin 2, conserved barrel domain protein
NXX57_RS19490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXX57_RS19495	COG0505	Belongs to the CarA family
NXX57_RS19505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXX57_RS19510	COG0070	glutamate synthase
NXX57_RS19510	COG0069	glutamate synthase activity
NXX57_RS19510	COG0067	glutamate synthase
NXX57_RS19520	COG0367	asparagine synthase
NXX57_RS19535	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXX57_RS19540	COG0436	Aminotransferase
NXX57_RS19550	COG0347	Belongs to the P(II) protein family
NXX57_RS19555	COG0004	ammonium transporteR
NXX57_RS19570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXX57_RS19580	COG0471	metal ion transport
NXX57_RS19580	COG0490	domain, Protein
NXX57_RS19590	COG1979	alcohol dehydrogenase
NXX57_RS19600	COG0133	tryptophan synthase activity
NXX57_RS19605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXX57_RS19615	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXX57_RS19620	COG0134	indole-3-glycerol-phosphate synthase activity
NXX57_RS19625	COG0135	phosphoribosylanthranilate isomerase activity
NXX57_RS19630	COG0159	tryptophan synthase activity
NXX57_RS19635	COG0252	asparaginase activity
NXX57_RS19645	COG0745	RESPONSE REGULATOR receiver
NXX57_RS19645	COG2205	protein histidine kinase activity
NXX57_RS19645	COG3292	Two component regulator propeller
NXX57_RS19650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXX57_RS19660	COG0110	maltose O-acetyltransferase activity
NXX57_RS19665	COG2197	response regulator
NXX57_RS19675	COG0138	bifunctional purine biosynthesis protein purh
NXX57_RS19685	COG0716	FMN binding
NXX57_RS19710	COG1132	(ABC) transporter
NXX57_RS19725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS19735	COG4771	TonB-dependent receptor
NXX57_RS19745	COG4771	TonB-dependent receptor
NXX57_RS19755	COG0490	domain, Protein
NXX57_RS19755	COG2985	domain, Protein
NXX57_RS19760	COG1230	cation diffusion facilitator family transporter
NXX57_RS19775	COG4771	TonB-dependent receptor
NXX57_RS19780	COG1429	ligase activity, forming nitrogen-metal bonds
NXX57_RS19815	COG1609	Transcriptional regulator
NXX57_RS19820	COG2721	sulfolactate sulfo-lyase activity
NXX57_RS19895	COG1733	regulation of RNA biosynthetic process
NXX57_RS19905	COG0784	Response regulator, receiver
NXX57_RS19905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX57_RS19905	COG2198	Histidine kinase
NXX57_RS19905	COG2205	protein histidine kinase activity
NXX57_RS19915	COG3275	phosphorelay sensor kinase activity
NXX57_RS19940	COG0228	four-way junction DNA binding
NXX57_RS19945	COG2188	Transcriptional regulator
NXX57_RS19950	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXX57_RS19960	COG1070	Carbohydrate kinase
NXX57_RS19970	COG0738	Major facilitator superfamily
NXX57_RS20030	COG1177	transmembrane transport
NXX57_RS20035	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXX57_RS20040	COG3842	ATPase activity
NXX57_RS20045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX57_RS20050	COG0058	SHG alpha-glucan phosphorylase activity
NXX57_RS20060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX57_RS20080	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXX57_RS20160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXX57_RS20165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX57_RS20170	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS20185	COG1295	ribonuclease BN
NXX57_RS20200	COG2972	Histidine kinase
NXX57_RS20205	COG3279	Response regulator of the LytR AlgR family
NXX57_RS20210	COG0704	Plays a role in the regulation of phosphate uptake
NXX57_RS20215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXX57_RS20220	COG0581	inorganic phosphate transmembrane transporter activity
NXX57_RS20225	COG0573	inorganic phosphate transmembrane transporter activity
NXX57_RS20235	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXX57_RS20245	COG0586	Pfam SNARE associated Golgi protein
NXX57_RS20255	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXX57_RS20270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXX57_RS20275	COG0167	dihydroorotate dehydrogenase activity
NXX57_RS20280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXX57_RS20310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXX57_RS20330	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS20340	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS20350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NXX57_RS20365	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS20415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXX57_RS20420	COG0497	DNA recombination
NXX57_RS20435	COG0592	DNA-directed DNA polymerase activity
NXX57_RS20455	COG0321	lipoyl(octanoyl) transferase activity
NXX57_RS20455	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXX57_RS20460	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXX57_RS20470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX57_RS20475	COG0156	8-amino-7-oxononanoate synthase activity
NXX57_RS20490	COG0019	diaminopimelate decarboxylase activity
NXX57_RS20495	COG0527	aspartate kinase activity
NXX57_RS20500	COG2884	Cell division ATP-binding protein ftsE
NXX57_RS20505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXX57_RS20505	COG0140	phosphoribosyl-ATP diphosphatase activity
NXX57_RS20510	COG0107	imidazoleglycerol-phosphate synthase activity
NXX57_RS20515	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXX57_RS20520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXX57_RS20525	COG0788	formyltetrahydrofolate deformylase activity
NXX57_RS20540	COG0693	protein deglycase activity
NXX57_RS20545	COG0656	L-ascorbic acid biosynthetic process
NXX57_RS20565	COG0534	Mate efflux family protein
NXX57_RS20570	COG2076	Multidrug Resistance protein
NXX57_RS20585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX57_RS20585	COG2885	chlorophyll binding
NXX57_RS20615	COG3546	catalase activity
NXX57_RS20645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXX57_RS20675	COG4946	Tricorn protease homolog
NXX57_RS20675	COG1506	peptidase
NXX57_RS20675	COG0823	Involved in the tonB-independent uptake of proteins
NXX57_RS20685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXX57_RS20690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NXX57_RS20705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXX57_RS20715	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXX57_RS20730	COG4771	TonB-dependent receptor
NXX57_RS20790	COG1312	Catalyzes the dehydration of D-mannonate
NXX57_RS20795	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS20800	COG1609	Transcriptional regulator
NXX57_RS20815	COG1929	Belongs to the glycerate kinase type-1 family
NXX57_RS20820	COG2223	nitrite transmembrane transporter activity
NXX57_RS20830	COG4771	TonB-dependent receptor
NXX57_RS20840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXX57_RS20840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXX57_RS20855	COG2226	methyltransferase
NXX57_RS20865	COG0784	Response regulator, receiver
NXX57_RS20865	COG5002	protein histidine kinase activity
NXX57_RS20870	COG0511	ligase activity, forming carbon-carbon bonds
NXX57_RS20875	COG0439	Biotin carboxylase
NXX57_RS20880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX57_RS20895	COG1620	l-lactate permease
NXX57_RS20900	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NXX57_RS20905	COG1690	Belongs to the RtcB family
NXX57_RS20945	COG0110	maltose O-acetyltransferase activity
NXX57_RS20955	COG0577	efflux transmembrane transporter activity
NXX57_RS20960	COG0577	efflux transmembrane transporter activity
NXX57_RS20960	COG1136	(ABC) transporter
NXX57_RS20975	COG2204	response regulator
NXX57_RS20985	COG0628	permease
NXX57_RS20990	COG1215	transferase activity, transferring glycosyl groups
NXX57_RS21000	COG0189	ligase activity
NXX57_RS21000	COG0569	domain protein
NXX57_RS21005	COG0577	efflux transmembrane transporter activity
NXX57_RS21005	COG1136	(ABC) transporter
NXX57_RS21010	COG0436	Aminotransferase
NXX57_RS21025	COG0488	(ABC) transporter
NXX57_RS21040	COG0745	RESPONSE REGULATOR receiver
NXX57_RS21045	COG5002	protein histidine kinase activity
NXX57_RS21090	COG3033	Beta-eliminating lyase
NXX57_RS21115	COG0629	single-stranded DNA binding
NXX57_RS21120	COG1194	a g-specific adenine glycosylase
NXX57_RS21130	COG1530	ribonuclease E activity
NXX57_RS21135	COG2885	chlorophyll binding
NXX57_RS21150	COG2885	chlorophyll binding
NXX57_RS21180	COG0305	Participates in initiation and elongation during chromosome replication
NXX57_RS21195	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS21200	COG3177	Filamentation induced by cAMP protein fic
NXX57_RS21220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXX57_RS21230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXX57_RS21245	COG4191	Histidine kinase
NXX57_RS21250	COG2204	response regulator
NXX57_RS21260	COG0784	Response regulator, receiver
NXX57_RS21260	COG2205	protein histidine kinase activity
NXX57_RS21260	COG5002	protein histidine kinase activity
NXX57_RS21280	COG1136	(ABC) transporter
NXX57_RS21290	COG1252	NADH dehydrogenase
NXX57_RS21295	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXX57_RS21310	COG3059	membrane
NXX57_RS21315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXX57_RS21320	COG2205	protein histidine kinase activity
NXX57_RS21320	COG0745	RESPONSE REGULATOR receiver
NXX57_RS21320	COG3292	Two component regulator propeller
NXX57_RS21335	COG3250	beta-galactosidase activity
NXX57_RS21340	COG0488	(ABC) transporter
NXX57_RS21365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXX57_RS21375	COG0739	heme binding
NXX57_RS21380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NXX57_RS21385	COG4206	TonB-dependent receptor
NXX57_RS21385	COG1629	transport
NXX57_RS21395	COG0686	Belongs to the AlaDH PNT family
NXX57_RS21440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXX57_RS21460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXX57_RS21470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXX57_RS21500	COG1595	DNA-templated transcription, initiation
NXX57_RS21515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXX57_RS21520	COG1741	Belongs to the pirin family
NXX57_RS21525	COG0259	pyridoxamine-phosphate oxidase activity
NXX57_RS21585	COG0456	acetyltransferase
NXX57_RS21645	COG0358	DNA primase activity
NXX57_RS21880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXX57_RS21880	COG1918	ferrous iron import across plasma membrane
NXX57_RS21885	COG0037	tRNA processing
NXX57_RS21900	COG3119	arylsulfatase activity
NXX57_RS21905	COG2205	protein histidine kinase activity
NXX57_RS21905	COG2202	Pas domain
NXX57_RS21910	COG2205	protein histidine kinase activity
NXX57_RS21910	COG2202	Pas domain
NXX57_RS21915	COG0534	Mate efflux family protein
NXX57_RS21920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXX57_RS21930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXX57_RS21935	COG1858	cytochrome C peroxidase
NXX57_RS21940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXX57_RS21955	COG1983	PspC domain protein
NXX57_RS21960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXX57_RS21985	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX57_RS22005	COG1629	transport
NXX57_RS22005	COG4206	TonB-dependent receptor
NXX57_RS22020	COG3119	arylsulfatase activity
NXX57_RS22025	COG0668	transmembrane transport
NXX57_RS22030	COG3119	arylsulfatase activity
NXX57_RS22040	COG3250	beta-galactosidase activity
NXX57_RS22045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX57_RS22050	COG3119	arylsulfatase activity
NXX57_RS22060	COG0702	epimerase
NXX57_RS22065	COG1629	transport
NXX57_RS22065	COG4206	TonB-dependent receptor
NXX57_RS22075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXX57_RS22080	COG1660	Displays ATPase and GTPase activities
NXX57_RS22085	COG3292	Two component regulator propeller
NXX57_RS22085	COG2205	protein histidine kinase activity
NXX57_RS22085	COG0745	RESPONSE REGULATOR receiver
NXX57_RS22085	COG3292	Two component regulator propeller
NXX57_RS22085	COG2205	protein histidine kinase activity
NXX57_RS22085	COG0745	RESPONSE REGULATOR receiver
NXX57_RS22090	COG3119	arylsulfatase activity
NXX57_RS22135	COG1091	dTDP-4-dehydrorhamnose reductase activity
NXX57_RS22150	COG0438	transferase activity, transferring glycosyl groups
NXX57_RS22160	COG1442	glycosyl transferase family 8
NXX57_RS22160	COG1216	Glycosyl transferase, family 2
NXX57_RS22220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXX57_RS22225	COG1830	Aldolase
NXX57_RS22230	COG0588	phosphoglycerate mutase activity
NXX57_RS22235	COG0784	Response regulator, receiver
NXX57_RS22235	COG2205	protein histidine kinase activity
NXX57_RS22240	COG1119	ATPase activity
NXX57_RS22245	COG1523	belongs to the glycosyl hydrolase 13 family
NXX57_RS22250	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXX57_RS22265	COG0560	Phosphoserine phosphatase
NXX57_RS22280	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXX57_RS22285	COG2814	Major facilitator Superfamily
NXX57_RS22290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXX57_RS22295	COG0126	phosphoglycerate kinase activity
NXX57_RS22315	COG0424	maF-like protein
NXX57_RS22335	COG0778	Nitroreductase
NXX57_RS22345	COG0288	reversible hydration of carbon dioxide
NXX57_RS22355	COG4771	TonB-dependent receptor
NXX57_RS22370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX57_RS22380	COG0511	ligase activity, forming carbon-carbon bonds
NXX57_RS22385	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXX57_RS22395	COG0191	fructose-bisphosphate aldolase activity
NXX57_RS22400	COG0254	rRNA binding
NXX57_RS22405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX57_RS22410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXX57_RS22480	COG1216	Glycosyl transferase, family 2
NXX57_RS22505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NXX57_RS22515	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NXX57_RS22520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXX57_RS22545	COG4750	Nucleotidyl transferase
NXX57_RS22585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXX57_RS22600	COG1280	lysine exporter protein (LysE YggA)
NXX57_RS22610	COG2205	protein histidine kinase activity
NXX57_RS22610	COG3292	Two component regulator propeller
NXX57_RS22610	COG2205	protein histidine kinase activity
NXX57_RS22610	COG0745	RESPONSE REGULATOR receiver
NXX57_RS22610	COG3292	Two component regulator propeller
NXX57_RS22610	COG0745	RESPONSE REGULATOR receiver
NXX57_RS22625	COG1649	PFAM Uncharacterised BCR, COG1649
NXX57_RS22650	COG1966	Carbon starvation protein
NXX57_RS22665	COG1649	PFAM Uncharacterised BCR, COG1649
NXX57_RS22690	COG2113	Glycine betaine
NXX57_RS22695	COG4176	ABC-type proline glycine betaine transport system permease component
NXX57_RS22715	COG2205	protein histidine kinase activity
NXX57_RS22715	COG0745	RESPONSE REGULATOR receiver
NXX57_RS22715	COG3292	Two component regulator propeller
NXX57_RS22725	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NXX57_RS22725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXX57_RS22735	COG1621	beta-fructofuranosidase activity
NXX57_RS22750	COG0561	phosphatase activity
NXX57_RS22755	COG4206	TonB-dependent receptor
NXX57_RS22755	COG1629	transport
NXX57_RS22765	COG1621	beta-fructofuranosidase activity
NXX57_RS22780	COG3250	beta-galactosidase activity
NXX57_RS22785	COG3537	Alpha-1,2-mannosidase
NXX57_RS22810	COG1629	transport
NXX57_RS22820	COG3250	beta-galactosidase activity
NXX57_RS22830	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS22840	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX57_RS22850	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXX57_RS22855	COG0475	glutathione-regulated potassium exporter activity
NXX57_RS22890	COG3279	Response regulator of the LytR AlgR family
NXX57_RS22920	COG2205	protein histidine kinase activity
NXX57_RS22925	COG2205	protein histidine kinase activity
NXX57_RS22930	COG2205	protein histidine kinase activity
NXX57_RS22945	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXX57_RS22955	COG1960	acyl-CoA dehydrogenase activity
NXX57_RS22980	COG1956	GAF domain-containing protein
NXX57_RS22990	COG0484	heat shock protein binding
NXX57_RS23015	COG1191	sigma factor activity
NXX57_RS23030	COG0028	Belongs to the TPP enzyme family
NXX57_RS23050	COG2885	chlorophyll binding
NXX57_RS23070	COG0459	protein refolding
NXX57_RS23075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXX57_RS23090	COG5002	protein histidine kinase activity
NXX57_RS23090	COG2205	protein histidine kinase activity
NXX57_RS23090	COG0784	Response regulator, receiver
NXX57_RS23105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXX57_RS23115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXX57_RS23120	COG0823	Involved in the tonB-independent uptake of proteins
NXX57_RS23120	COG1506	peptidase
NXX57_RS23130	COG0124	histidyl-tRNA synthetase
NXX57_RS23145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXX57_RS23170	COG0514	ATP-dependent DNA helicase (RecQ)
NXX57_RS23185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXX57_RS23195	COG0671	phosphoesterase, PA-phosphatase related
NXX57_RS23210	COG0473	3-isopropylmalate dehydrogenase activity
NXX57_RS23220	COG0066	3-isopropylmalate dehydratase activity
NXX57_RS23225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXX57_RS23230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXX57_RS23295	COG0463	Glycosyl transferase, family 2
NXX57_RS23305	COG4948	Mandelate Racemase Muconate Lactonizing
NXX57_RS23315	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX57_RS23320	COG0702	epimerase
NXX57_RS23325	COG4771	TonB-dependent receptor
NXX57_RS23330	COG4206	TonB-dependent receptor
NXX57_RS23330	COG1629	transport
NXX57_RS23350	COG0616	signal peptide processing
NXX57_RS23355	COG1663	tetraacyldisaccharide 4'-kinase activity
NXX57_RS23360	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXX57_RS23365	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXX57_RS23385	COG0513	Belongs to the DEAD box helicase family
NXX57_RS23390	COG2070	2-Nitropropane dioxygenase
NXX57_RS23395	COG0724	RNA recognition motif
NXX57_RS23410	COG3973	AAA domain
NXX57_RS23430	COG1704	LemA family
NXX57_RS23445	COG0534	Mate efflux family protein
NXX57_RS23455	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXX57_RS23465	COG4977	sequence-specific DNA binding
NXX57_RS23465	COG1917	Cupin 2, conserved barrel domain protein
NXX57_RS23495	COG1028	Short-chain dehydrogenase reductase Sdr
NXX57_RS23505	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXX57_RS23515	COG0439	Biotin carboxylase
NXX57_RS23520	COG5016	pyruvate
NXX57_RS23520	COG0511	ligase activity, forming carbon-carbon bonds
NXX57_RS23525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX57_RS23535	COG2855	membrane
NXX57_RS23545	COG2873	o-acetylhomoserine
NXX57_RS23585	COG1538	Outer membrane efflux protein
NXX57_RS23615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXX57_RS23635	COG0024	Methionine aminopeptidase
NXX57_RS23640	COG0617	tRNA 3'-terminal CCA addition
NXX57_RS23660	COG0632	four-way junction helicase activity
NXX57_RS23665	COG0673	inositol 2-dehydrogenase activity
NXX57_RS23695	COG1272	protein, Hemolysin III
NXX57_RS23710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXX57_RS23715	COG1328	CTP reductase activity
NXX57_RS23715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXX57_RS23720	COG0602	queuosine metabolic process
NXX57_RS23725	COG2814	Major facilitator Superfamily
NXX57_RS23730	COG0750	zinc metalloprotease
NXX57_RS23735	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXX57_RS23745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXX57_RS23750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXX57_RS23770	COG0194	GDP metabolic process
NXX57_RS23775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXX57_RS23780	COG1408	metallophosphoesterase
NXX57_RS23785	COG1575	Belongs to the MenA family. Type 1 subfamily
NXX57_RS23790	COG1088	dTDP-glucose 4,6-dehydratase activity
NXX57_RS23795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXX57_RS23805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXX57_RS23825	COG2205	protein histidine kinase activity
NXX57_RS23855	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX57_RS23870	COG4771	TonB-dependent receptor
NXX57_RS23885	COG0784	Response regulator, receiver
NXX57_RS23885	COG2205	protein histidine kinase activity
NXX57_RS23890	COG0488	(ABC) transporter
NXX57_RS23930	COG1595	DNA-templated transcription, initiation
NXX57_RS23945	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXX57_RS23955	COG1522	sequence-specific DNA binding
NXX57_RS23985	COG0811	peptide transport
NXX57_RS23995	COG0084	hydrolase, TatD family'
NXX57_RS24015	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXX57_RS24020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXX57_RS24025	COG0205	6-phosphofructokinase activity
NXX57_RS24050	COG0372	Belongs to the citrate synthase family
NXX57_RS24055	COG0538	isocitrate dehydrogenase activity
NXX57_RS24060	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXX57_RS24065	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX57_RS24075	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXX57_RS24090	COG0028	Belongs to the TPP enzyme family
NXX57_RS24095	COG0129	dihydroxy-acid dehydratase activity
NXX57_RS24100	COG1047	Peptidyl-prolyl cis-trans
NXX57_RS24105	COG3681	Belongs to the UPF0597 family
NXX57_RS24125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXX57_RS24170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX57_RS24170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX57_RS24175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX57_RS24180	COG0569	domain protein
NXX57_RS24180	COG2985	domain, Protein
NXX57_RS24190	COG1492	cobalamin metabolic process
NXX57_RS24235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXX57_RS24240	COG1120	ATPase activity
NXX57_RS24250	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NXX57_RS24260	COG0534	Mate efflux family protein
NXX57_RS24270	COG2188	Transcriptional regulator
NXX57_RS24290	COG1629	transport
NXX57_RS24290	COG4206	TonB-dependent receptor
NXX57_RS24355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXX57_RS24360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXX57_RS24365	COG0166	Belongs to the GPI family
NXX57_RS24395	COG2502	aspartate--ammonia ligase
NXX57_RS24400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXX57_RS24415	COG3876	Protein conserved in bacteria
NXX57_RS24435	COG0860	N-Acetylmuramoyl-L-alanine amidase