locus-tag	class	description
NXV61_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXV61_RS00010	COG0778	Nitroreductase
NXV61_RS00020	COG1640	4-alpha-glucanotransferase
NXV61_RS00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NXV61_RS00055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV61_RS00060	COG0318	PFAM AMP-dependent synthetase and ligase
NXV61_RS00095	COG0359	binds to the 23S rRNA
NXV61_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXV61_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
NXV61_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXV61_RS00135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXV61_RS00165	COG1131	(ABC) transporter
NXV61_RS00175	COG2431	L-lysine efflux transmembrane transporter activity
NXV61_RS00185	COG1193	negative regulation of DNA recombination
NXV61_RS00210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXV61_RS00225	COG2234	aminopeptidase activity
NXV61_RS00230	COG3250	beta-galactosidase activity
NXV61_RS00250	COG0702	epimerase
NXV61_RS00255	COG1629	transport
NXV61_RS00270	COG3537	Alpha-1,2-mannosidase
NXV61_RS00285	COG4206	TonB-dependent receptor
NXV61_RS00285	COG1629	transport
NXV61_RS00305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXV61_RS00310	COG0802	atpase or kinase
NXV61_RS00335	COG0714	Associated with various cellular activities
NXV61_RS00385	COG3385	transposase activity
NXV61_RS00420	COG3118	belongs to the thioredoxin family
NXV61_RS00430	COG0688	phosphatidylethanolamine metabolic process
NXV61_RS00435	COG1183	phosphatidylcholine synthase activity
NXV61_RS00455	COG0792	nuclease activity
NXV61_RS00470	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV61_RS00480	COG0534	Mate efflux family protein
NXV61_RS00485	COG0528	UMP kinase activity
NXV61_RS00520	COG0233	cytoplasmic translational termination
NXV61_RS00525	COG1162	GTPase activity
NXV61_RS00535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXV61_RS00565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXV61_RS00585	COG1629	transport
NXV61_RS00585	COG4206	TonB-dependent receptor
NXV61_RS00615	COG4771	TonB-dependent receptor
NXV61_RS00625	COG2095	MarC family integral membrane protein
NXV61_RS00640	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXV61_RS00650	COG1435	thymidine kinase activity
NXV61_RS00655	COG0628	permease
NXV61_RS00730	COG2433	Pfam Transposase IS66
NXV61_RS00740	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS00755	COG3292	Two component regulator propeller
NXV61_RS00755	COG2205	protein histidine kinase activity
NXV61_RS00755	COG0745	RESPONSE REGULATOR receiver
NXV61_RS00770	COG0702	epimerase
NXV61_RS00775	COG1629	transport
NXV61_RS00785	COG4771	TonB-dependent receptor
NXV61_RS00790	COG1595	DNA-templated transcription, initiation
NXV61_RS00795	COG1082	Xylose isomerase domain protein TIM barrel
NXV61_RS00810	COG4771	TonB-dependent receptor
NXV61_RS00845	COG0693	protein deglycase activity
NXV61_RS00890	COG0110	maltose O-acetyltransferase activity
NXV61_RS00900	COG1522	sequence-specific DNA binding
NXV61_RS00925	COG0745	RESPONSE REGULATOR receiver
NXV61_RS00925	COG2205	protein histidine kinase activity
NXV61_RS00925	COG3292	Two component regulator propeller
NXV61_RS00960	COG2818	Glycosylase
NXV61_RS00965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXV61_RS00970	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXV61_RS00980	COG0252	asparaginase activity
NXV61_RS00990	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXV61_RS00995	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXV61_RS01005	COG4771	TonB-dependent receptor
NXV61_RS01025	COG0826	peptidase U32
NXV61_RS01030	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXV61_RS01040	COG0436	Aminotransferase
NXV61_RS01045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXV61_RS01120	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXV61_RS01130	COG3119	arylsulfatase activity
NXV61_RS01150	COG0702	epimerase
NXV61_RS01165	COG1629	transport
NXV61_RS01195	COG1595	DNA-templated transcription, initiation
NXV61_RS01205	COG1629	transport
NXV61_RS01230	COG0673	inositol 2-dehydrogenase activity
NXV61_RS01240	COG0673	inositol 2-dehydrogenase activity
NXV61_RS01330	COG1596	polysaccharide export
NXV61_RS01350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXV61_RS01355	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS01365	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS01410	COG0463	Glycosyl transferase, family 2
NXV61_RS01480	COG0519	Catalyzes the synthesis of GMP from XMP
NXV61_RS01485	COG5002	protein histidine kinase activity
NXV61_RS01490	COG2205	protein histidine kinase activity
NXV61_RS01500	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXV61_RS01510	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXV61_RS01560	COG3250	beta-galactosidase activity
NXV61_RS01565	COG2204	response regulator
NXV61_RS01570	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXV61_RS01595	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS01600	COG0737	Belongs to the 5'-nucleotidase family
NXV61_RS01605	COG0737	Belongs to the 5'-nucleotidase family
NXV61_RS01640	COG0335	large ribosomal subunit rRNA binding
NXV61_RS01650	COG1940	carbohydrate kinase activity
NXV61_RS01655	COG1136	(ABC) transporter
NXV61_RS01655	COG0577	efflux transmembrane transporter activity
NXV61_RS01660	COG1136	(ABC) transporter
NXV61_RS01660	COG0577	efflux transmembrane transporter activity
NXV61_RS01665	COG1136	(ABC) transporter
NXV61_RS01665	COG0577	efflux transmembrane transporter activity
NXV61_RS01680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXV61_RS01680	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXV61_RS01690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXV61_RS01710	COG2996	Protein conserved in bacteria
NXV61_RS01720	COG1629	transport
NXV61_RS01745	COG0039	L-malate dehydrogenase activity
NXV61_RS01755	COG2217	Heavy metal translocating P-type atpase
NXV61_RS01775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXV61_RS01780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXV61_RS01785	COG0509	glycine decarboxylation via glycine cleavage system
NXV61_RS01815	COG0006	proline dipeptidase activity
NXV61_RS01820	COG3250	beta-galactosidase activity
NXV61_RS01825	COG3408	Glycogen debranching enzyme
NXV61_RS01830	COG3458	cephalosporin-C deacetylase activity
NXV61_RS01845	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXV61_RS01865	COG4206	TonB-dependent receptor
NXV61_RS01865	COG1629	transport
NXV61_RS01900	COG1773	rubredoxin
NXV61_RS01910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXV61_RS01915	COG1011	Hydrolase
NXV61_RS01920	COG0196	riboflavin kinase activity
NXV61_RS01925	COG1266	CAAX protease self-immunity
NXV61_RS01935	COG3655	Transcriptional regulator
NXV61_RS01940	COG2166	iron-sulfur cluster assembly
NXV61_RS01945	COG2234	aminopeptidase activity
NXV61_RS01950	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXV61_RS01960	COG0280	phosphate acetyltransferase
NXV61_RS01965	COG3426	butyrate kinase activity
NXV61_RS02015	COG1185	polyribonucleotide nucleotidyltransferase activity
NXV61_RS02025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXV61_RS02045	COG1595	DNA-templated transcription, initiation
NXV61_RS02050	COG0076	glutamate decarboxylase activity
NXV61_RS02055	COG2066	Belongs to the glutaminase family
NXV61_RS02065	COG0531	amino acid
NXV61_RS02280	COG1192	Involved in chromosome partitioning
NXV61_RS02450	COG3209	COG3209 Rhs family protein
NXV61_RS02465	COG2433	Pfam Transposase IS66
NXV61_RS02505	COG3209	COG3209 Rhs family protein
NXV61_RS02550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXV61_RS02560	COG0784	Response regulator, receiver
NXV61_RS02560	COG2205	protein histidine kinase activity
NXV61_RS02585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXV61_RS02585	COG0551	DNA topoisomerase type I activity
NXV61_RS02795	COG0667	Aldo Keto reductase
NXV61_RS02800	COG3250	beta-galactosidase activity
NXV61_RS02830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS02840	COG1309	transcriptional regulator
NXV61_RS02845	COG2986	histidine ammonia-lyase
NXV61_RS02855	COG1228	amidohydrolase
NXV61_RS02865	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXV61_RS02875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXV61_RS02890	COG0203	ribosomal protein L17
NXV61_RS02895	COG0202	RNA polymerase activity
NXV61_RS02900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXV61_RS02905	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXV61_RS02910	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXV61_RS02915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXV61_RS02920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXV61_RS02935	COG0200	Binds to the 23S rRNA
NXV61_RS02940	COG1841	ribosomal large subunit assembly
NXV61_RS02945	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXV61_RS02950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXV61_RS02955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXV61_RS02960	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXV61_RS02965	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXV61_RS02970	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXV61_RS02975	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXV61_RS02980	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXV61_RS02985	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXV61_RS02990	COG0255	Belongs to the universal ribosomal protein uL29 family
NXV61_RS02995	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXV61_RS03000	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXV61_RS03005	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXV61_RS03010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXV61_RS03015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXV61_RS03020	COG0089	rRNA binding
NXV61_RS03025	COG0088	Forms part of the polypeptide exit tunnel
NXV61_RS03030	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXV61_RS03035	COG0051	transcription antitermination factor activity, RNA binding
NXV61_RS03040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXV61_RS03045	COG0049	tRNA binding
NXV61_RS03050	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXV61_RS03060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXV61_RS03065	COG0085	RNA polymerase activity
NXV61_RS03070	COG0222	ribosome binding
NXV61_RS03075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXV61_RS03080	COG0081	regulation of translation
NXV61_RS03085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXV61_RS03095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXV61_RS03105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXV61_RS03140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXV61_RS03145	COG0006	proline dipeptidase activity
NXV61_RS03150	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXV61_RS03160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXV61_RS03170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXV61_RS03180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXV61_RS03195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXV61_RS03200	COG1027	Aspartate ammonia-lyase
NXV61_RS03205	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXV61_RS03210	COG0252	asparaginase activity
NXV61_RS03225	COG2096	Adenosyltransferase
NXV61_RS03240	COG3279	Response regulator of the LytR AlgR family
NXV61_RS03260	COG0515	serine threonine protein kinase
NXV61_RS03260	COG2815	serine threonine protein kinase
NXV61_RS03275	COG0515	serine threonine protein kinase
NXV61_RS03275	COG2815	serine threonine protein kinase
NXV61_RS03285	COG0631	protein serine/threonine phosphatase activity
NXV61_RS03335	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXV61_RS03335	COG0662	Cupin 2, conserved barrel domain protein
NXV61_RS03340	COG0318	PFAM AMP-dependent synthetase and ligase
NXV61_RS03345	COG1396	sequence-specific DNA binding
NXV61_RS03360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXV61_RS03375	COG2059	Chromate
NXV61_RS03380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXV61_RS03385	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXV61_RS03415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXV61_RS03425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV61_RS03455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV61_RS03460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXV61_RS03465	COG1629	transport
NXV61_RS03465	COG4206	TonB-dependent receptor
NXV61_RS03495	COG3634	alkyl hydroperoxide reductase activity
NXV61_RS03515	COG2816	NAD+ diphosphatase activity
NXV61_RS03530	COG1629	transport
NXV61_RS03570	COG0745	RESPONSE REGULATOR receiver
NXV61_RS03570	COG3292	Two component regulator propeller
NXV61_RS03570	COG2205	protein histidine kinase activity
NXV61_RS03585	COG0018	arginyl-trna synthetase
NXV61_RS03595	COG0705	Rhomboid family
NXV61_RS03610	COG0339	signal peptide processing
NXV61_RS03615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXV61_RS03885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXV61_RS03950	COG3723	Recombinational DNA repair protein, rece pathway
NXV61_RS03955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXV61_RS04015	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXV61_RS04015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXV61_RS04020	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXV61_RS04030	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXV61_RS04050	COG4974	Belongs to the 'phage' integrase family
NXV61_RS04065	COG0606	chelatase, subunit chli
NXV61_RS04085	COG2205	protein histidine kinase activity
NXV61_RS04105	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS04110	COG3250	beta-galactosidase activity
NXV61_RS04125	COG0561	phosphatase activity
NXV61_RS04130	COG1629	transport
NXV61_RS04130	COG4206	TonB-dependent receptor
NXV61_RS04135	COG0745	RESPONSE REGULATOR receiver
NXV61_RS04135	COG3292	Two component regulator propeller
NXV61_RS04135	COG2205	protein histidine kinase activity
NXV61_RS04135	COG0745	RESPONSE REGULATOR receiver
NXV61_RS04135	COG2205	protein histidine kinase activity
NXV61_RS04135	COG3292	Two component regulator propeller
NXV61_RS04145	COG0489	protein tyrosine kinase activity
NXV61_RS04160	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS04165	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS04180	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS04185	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NXV61_RS04205	COG1442	glycosyl transferase family 8
NXV61_RS04220	COG1216	Glycosyl transferase, family 2
NXV61_RS04220	COG1442	glycosyl transferase family 8
NXV61_RS04275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS04320	COG4771	TonB-dependent receptor
NXV61_RS04375	COG4771	TonB-dependent receptor
NXV61_RS04380	COG1629	transport
NXV61_RS04380	COG4206	TonB-dependent receptor
NXV61_RS04420	COG3940	Belongs to the glycosyl hydrolase 43 family
NXV61_RS04425	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV61_RS04430	COG3119	arylsulfatase activity
NXV61_RS04455	COG0702	epimerase
NXV61_RS04465	COG1629	transport
NXV61_RS04465	COG4206	TonB-dependent receptor
NXV61_RS04475	COG3250	beta-galactosidase activity
NXV61_RS04540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV61_RS04540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV61_RS04560	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS04570	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS04640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXV61_RS04650	COG1216	Glycosyl transferase, family 2
NXV61_RS04695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXV61_RS04700	COG3385	transposase activity
NXV61_RS04705	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV61_RS04710	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV61_RS04770	COG1629	transport
NXV61_RS04775	COG0561	phosphatase activity
NXV61_RS04820	COG4206	TonB-dependent receptor
NXV61_RS04820	COG1629	transport
NXV61_RS04825	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS04840	COG1629	transport
NXV61_RS04840	COG4206	TonB-dependent receptor
NXV61_RS04880	COG1373	ATPase (AAA superfamily
NXV61_RS04885	COG4771	TonB-dependent receptor
NXV61_RS04905	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXV61_RS04910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXV61_RS04930	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXV61_RS04935	COG3409	Peptidoglycan-binding domain 1 protein
NXV61_RS04935	COG0793	Belongs to the peptidase S41A family
NXV61_RS04990	COG1629	transport
NXV61_RS05010	COG3292	Two component regulator propeller
NXV61_RS05010	COG0745	RESPONSE REGULATOR receiver
NXV61_RS05010	COG2205	protein histidine kinase activity
NXV61_RS05020	COG3119	arylsulfatase activity
NXV61_RS05035	COG1053	succinate dehydrogenase
NXV61_RS05040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXV61_RS05055	COG3119	arylsulfatase activity
NXV61_RS05090	COG3345	alpha-galactosidase
NXV61_RS05110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXV61_RS05110	COG0758	DNA mediated transformation
NXV61_RS05120	COG0826	peptidase U32
NXV61_RS05125	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXV61_RS05140	COG0557	exoribonuclease II activity
NXV61_RS05165	COG4206	TonB-dependent receptor
NXV61_RS05165	COG1629	transport
NXV61_RS05175	COG0561	phosphatase activity
NXV61_RS05185	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS05195	COG1917	Cupin 2, conserved barrel domain protein
NXV61_RS05200	COG1621	beta-fructofuranosidase activity
NXV61_RS05215	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS05235	COG0702	epimerase
NXV61_RS05240	COG4771	TonB-dependent receptor
NXV61_RS05265	COG3408	Glycogen debranching enzyme
NXV61_RS05265	COG3119	arylsulfatase activity
NXV61_RS05275	COG2205	protein histidine kinase activity
NXV61_RS05275	COG3292	Two component regulator propeller
NXV61_RS05275	COG0745	RESPONSE REGULATOR receiver
NXV61_RS05290	COG3119	arylsulfatase activity
NXV61_RS05300	COG4771	TonB-dependent receptor
NXV61_RS05325	COG3119	arylsulfatase activity
NXV61_RS05345	COG2814	Major facilitator Superfamily
NXV61_RS05350	COG0012	GTP binding
NXV61_RS05355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXV61_RS05360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXV61_RS05380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXV61_RS05385	COG2207	Transcriptional regulator
NXV61_RS05385	COG0662	Cupin 2, conserved barrel domain protein
NXV61_RS05390	COG0697	spore germination
NXV61_RS05400	COG0495	leucyl-tRNA aminoacylation
NXV61_RS05405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXV61_RS05410	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXV61_RS05415	COG1360	Flagellar Motor Protein
NXV61_RS05420	COG3537	Alpha-1,2-mannosidase
NXV61_RS05440	COG0745	RESPONSE REGULATOR receiver
NXV61_RS05440	COG2205	protein histidine kinase activity
NXV61_RS05440	COG0745	RESPONSE REGULATOR receiver
NXV61_RS05440	COG3292	Two component regulator propeller
NXV61_RS05440	COG3292	Two component regulator propeller
NXV61_RS05440	COG2205	protein histidine kinase activity
NXV61_RS05460	COG4771	TonB-dependent receptor
NXV61_RS05475	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS05485	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS05490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXV61_RS05510	COG0731	radical SAM domain protein
NXV61_RS05510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXV61_RS05515	COG3119	arylsulfatase activity
NXV61_RS05540	COG0659	secondary active sulfate transmembrane transporter activity
NXV61_RS05545	COG1592	Rubrerythrin
NXV61_RS05570	COG2027	D-alanyl-D-alanine carboxypeptidase
NXV61_RS05600	COG0427	acetyl-CoA hydrolase
NXV61_RS05610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV61_RS05640	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS05715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXV61_RS05720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXV61_RS05725	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXV61_RS05740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXV61_RS05780	COG0594	ribonuclease P activity
NXV61_RS05785	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXV61_RS05795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXV61_RS05805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXV61_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS05850	COG4206	TonB-dependent receptor
NXV61_RS05850	COG1629	transport
NXV61_RS05875	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXV61_RS05890	COG1121	(ABC) transporter
NXV61_RS05900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXV61_RS05900	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NXV61_RS05905	COG1238	metal cluster binding
NXV61_RS05920	COG0823	Involved in the tonB-independent uptake of proteins
NXV61_RS05920	COG1506	peptidase
NXV61_RS05925	COG0116	Belongs to the methyltransferase superfamily
NXV61_RS05925	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXV61_RS05930	COG1045	serine acetyltransferase
NXV61_RS05935	COG3275	phosphorelay sensor kinase activity
NXV61_RS05940	COG3279	Response regulator of the LytR AlgR family
NXV61_RS05955	COG0142	geranyltranstransferase activity
NXV61_RS05970	COG1694	Mazg nucleotide pyrophosphohydrolase
NXV61_RS05975	COG1490	D-aminoacyl-tRNA deacylase activity
NXV61_RS05980	COG0322	excinuclease ABC activity
NXV61_RS05985	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXV61_RS05990	COG0445	tRNA wobble uridine modification
NXV61_RS06005	COG4771	TonB-dependent receptor
NXV61_RS06035	COG2197	response regulator
NXV61_RS06045	COG4206	TonB-dependent receptor
NXV61_RS06045	COG1629	transport
NXV61_RS06075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXV61_RS06080	COG0700	Nucleoside recognition
NXV61_RS06085	COG2255	four-way junction helicase activity
NXV61_RS06105	COG3591	Belongs to the peptidase S1B family
NXV61_RS06115	COG3250	beta-galactosidase activity
NXV61_RS06120	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS06130	COG0702	epimerase
NXV61_RS06135	COG4771	TonB-dependent receptor
NXV61_RS06150	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS06200	COG0612	Peptidase, M16
NXV61_RS06210	COG4771	TonB-dependent receptor
NXV61_RS06215	COG0702	epimerase
NXV61_RS06230	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS06245	COG0681	Belongs to the peptidase S26 family
NXV61_RS06255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXV61_RS06265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV61_RS06285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXV61_RS06315	COG4771	TonB-dependent receptor
NXV61_RS06325	COG3292	Two component regulator propeller
NXV61_RS06325	COG0745	RESPONSE REGULATOR receiver
NXV61_RS06325	COG2205	protein histidine kinase activity
NXV61_RS06325	COG3292	Two component regulator propeller
NXV61_RS06325	COG0745	RESPONSE REGULATOR receiver
NXV61_RS06325	COG2205	protein histidine kinase activity
NXV61_RS06335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV61_RS06340	COG1538	Outer membrane efflux protein
NXV61_RS06355	COG3250	beta-galactosidase activity
NXV61_RS06380	COG0702	epimerase
NXV61_RS06385	COG4771	TonB-dependent receptor
NXV61_RS06395	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV61_RS06400	COG3119	arylsulfatase activity
NXV61_RS06405	COG5492	domain, Protein
NXV61_RS06410	COG0215	cysteine-tRNA ligase activity
NXV61_RS06415	COG0561	phosphatase activity
NXV61_RS06420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXV61_RS06425	COG0482	sulfurtransferase activity
NXV61_RS06435	COG0205	6-phosphofructokinase activity
NXV61_RS06440	COG0571	ribonuclease III activity
NXV61_RS06445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXV61_RS06450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXV61_RS06460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXV61_RS06490	COG1216	Glycosyl transferase, family 2
NXV61_RS06490	COG1442	glycosyl transferase family 8
NXV61_RS06515	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS06540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXV61_RS06545	COG0436	Aminotransferase
NXV61_RS06565	COG0463	Glycosyl transferase, family 2
NXV61_RS06600	COG1132	(ABC) transporter
NXV61_RS06625	COG0328	RNA-DNA hybrid ribonuclease activity
NXV61_RS06625	COG3341	Caulimovirus viroplasmin
NXV61_RS06635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXV61_RS06640	COG1166	arginine decarboxylase activity
NXV61_RS06645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NXV61_RS06650	COG1595	DNA-templated transcription, initiation
NXV61_RS06680	COG0779	Required for maturation of 30S ribosomal subunits
NXV61_RS06685	COG0195	Participates in both transcription termination and antitermination
NXV61_RS06690	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXV61_RS06700	COG0719	Fe-S assembly protein
NXV61_RS06705	COG0396	ATPase activity
NXV61_RS06710	COG0719	Fe-S assembly protein
NXV61_RS06715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXV61_RS06720	COG0393	Putative heavy-metal-binding
NXV61_RS06730	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXV61_RS06735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXV61_RS06760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXV61_RS06820	COG0187	DNA topoisomerase II activity
NXV61_RS06825	COG0268	Binds directly to 16S ribosomal RNA
NXV61_RS06840	COG1381	Involved in DNA repair and RecF pathway recombination
NXV61_RS06895	COG1610	YqeY-like protein
NXV61_RS06900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXV61_RS06920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXV61_RS06925	COG0772	Belongs to the SEDS family
NXV61_RS06930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXV61_RS06935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXV61_RS06940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXV61_RS06955	COG0275	rRNA processing
NXV61_RS06960	COG2001	Belongs to the MraZ family
NXV61_RS06965	COG1595	DNA-templated transcription, initiation
NXV61_RS06980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXV61_RS06985	COG0756	dUTP diphosphatase activity
NXV61_RS07000	COG4942	peptidase
NXV61_RS07005	COG0745	RESPONSE REGULATOR receiver
NXV61_RS07005	COG2205	protein histidine kinase activity
NXV61_RS07005	COG3292	Two component regulator propeller
NXV61_RS07025	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07035	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07045	COG0702	epimerase
NXV61_RS07050	COG4771	TonB-dependent receptor
NXV61_RS07085	COG3119	arylsulfatase activity
NXV61_RS07145	COG0702	epimerase
NXV61_RS07150	COG4771	TonB-dependent receptor
NXV61_RS07190	COG4771	TonB-dependent receptor
NXV61_RS07195	COG0702	epimerase
NXV61_RS07265	COG1629	transport
NXV61_RS07270	COG0561	phosphatase activity
NXV61_RS07305	COG3537	Alpha-1,2-mannosidase
NXV61_RS07320	COG3537	Alpha-1,2-mannosidase
NXV61_RS07330	COG2017	converts alpha-aldose to the beta-anomer
NXV61_RS07450	COG1373	ATPase (AAA superfamily
NXV61_RS07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXV61_RS07460	COG1022	Amp-dependent synthetase and ligase
NXV61_RS07465	COG0612	Peptidase, M16
NXV61_RS07485	COG2954	triphosphatase activity
NXV61_RS07545	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS07555	COG4771	TonB-dependent receptor
NXV61_RS07610	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07615	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07635	COG0363	glucosamine-6-phosphate deaminase activity
NXV61_RS07640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXV61_RS07685	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS07700	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07705	COG0673	inositol 2-dehydrogenase activity
NXV61_RS07715	COG0702	epimerase
NXV61_RS07720	COG4771	TonB-dependent receptor
NXV61_RS07730	COG2814	Major facilitator Superfamily
NXV61_RS07740	COG3458	cephalosporin-C deacetylase activity
NXV61_RS07745	COG1609	Transcriptional regulator
NXV61_RS07745	COG2207	Transcriptional regulator
NXV61_RS07755	COG0423	glycine-tRNA ligase activity
NXV61_RS07770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXV61_RS07770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NXV61_RS07790	COG1609	Transcriptional regulator
NXV61_RS07805	COG0738	Major facilitator superfamily
NXV61_RS07810	COG1063	alcohol dehydrogenase
NXV61_RS07825	COG2211	Major facilitator Superfamily
NXV61_RS07830	COG2385	sporulation resulting in formation of a cellular spore
NXV61_RS07830	COG2247	cell wall binding repeat
NXV61_RS07840	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS07845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXV61_RS07920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS07990	COG0562	UDP-galactopyranose mutase
NXV61_RS07995	COG1216	Glycosyl transferase, family 2
NXV61_RS07995	COG0463	Glycosyl transferase, family 2
NXV61_RS08005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXV61_RS08010	COG0475	glutathione-regulated potassium exporter activity
NXV61_RS08010	COG0589	response to stress
NXV61_RS08015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXV61_RS08020	COG1136	(ABC) transporter
NXV61_RS08030	COG0733	neurotransmitter:sodium symporter activity
NXV61_RS08040	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXV61_RS08045	COG0784	Response regulator, receiver
NXV61_RS08045	COG5002	protein histidine kinase activity
NXV61_RS08055	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXV61_RS08060	COG0312	modulator of DNA gyrase
NXV61_RS08065	COG0312	modulator of DNA gyrase
NXV61_RS08070	COG1704	LemA family
NXV61_RS08100	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV61_RS08110	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS08120	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS08130	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV61_RS08140	COG1082	Xylose isomerase domain protein TIM barrel
NXV61_RS08205	COG2205	protein histidine kinase activity
NXV61_RS08205	COG3292	Two component regulator propeller
NXV61_RS08205	COG0745	RESPONSE REGULATOR receiver
NXV61_RS08220	COG4771	TonB-dependent receptor
NXV61_RS08270	COG1346	cytolysis
NXV61_RS08275	COG1380	Effector of murein hydrolase LrgA
NXV61_RS08280	COG0280	phosphate acetyltransferase
NXV61_RS08285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXV61_RS08290	COG0463	Glycosyl transferase, family 2
NXV61_RS08290	COG1216	Glycosyl transferase, family 2
NXV61_RS08295	COG2003	Belongs to the UPF0758 family
NXV61_RS08305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV61_RS08310	COG0366	Alpha amylase catalytic
NXV61_RS08325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV61_RS08330	COG1629	transport
NXV61_RS08330	COG4206	TonB-dependent receptor
NXV61_RS08335	COG1082	Xylose isomerase domain protein TIM barrel
NXV61_RS08340	COG0366	Alpha amylase catalytic
NXV61_RS08350	COG1785	Belongs to the alkaline phosphatase family
NXV61_RS08355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXV61_RS08360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXV61_RS08365	COG2815	serine threonine protein kinase
NXV61_RS08365	COG0515	serine threonine protein kinase
NXV61_RS08370	COG0564	pseudouridine synthase activity
NXV61_RS08375	COG1181	Belongs to the D-alanine--D-alanine ligase family
NXV61_RS08395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXV61_RS08400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXV61_RS08405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXV61_RS08410	COG0436	Aminotransferase
NXV61_RS08420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXV61_RS08440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXV61_RS08445	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXV61_RS08455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXV61_RS08455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXV61_RS08460	COG2890	protein-(glutamine-N5) methyltransferase activity
NXV61_RS08470	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXV61_RS08480	COG0165	Argininosuccinate lyase
NXV61_RS08520	COG0471	metal ion transport
NXV61_RS08585	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXV61_RS08675	COG0740	serine-type endopeptidase activity
NXV61_RS08825	COG4771	TonB-dependent receptor
NXV61_RS08845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXV61_RS08850	COG1917	Cupin 2, conserved barrel domain protein
NXV61_RS08850	COG1396	sequence-specific DNA binding
NXV61_RS08855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXV61_RS08860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXV61_RS08865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXV61_RS08870	COG0137	argininosuccinate synthase activity
NXV61_RS08880	COG1438	arginine binding
NXV61_RS08885	COG1070	Carbohydrate kinase
NXV61_RS08890	COG4806	L-rhamnose isomerase
NXV61_RS08905	COG1454	alcohol dehydrogenase
NXV61_RS08935	COG0564	pseudouridine synthase activity
NXV61_RS09000	COG3537	Alpha-1,2-mannosidase
NXV61_RS09005	COG0745	RESPONSE REGULATOR receiver
NXV61_RS09005	COG2205	protein histidine kinase activity
NXV61_RS09005	COG3292	Two component regulator propeller
NXV61_RS09015	COG4206	TonB-dependent receptor
NXV61_RS09015	COG1629	transport
NXV61_RS09020	COG0702	epimerase
NXV61_RS09060	COG3119	arylsulfatase activity
NXV61_RS09065	COG2205	protein histidine kinase activity
NXV61_RS09065	COG3292	Two component regulator propeller
NXV61_RS09065	COG0745	RESPONSE REGULATOR receiver
NXV61_RS09070	COG2204	response regulator
NXV61_RS09075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXV61_RS09080	COG0612	Peptidase, M16
NXV61_RS09085	COG0534	Mate efflux family protein
NXV61_RS09090	COG2205	protein histidine kinase activity
NXV61_RS09090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV61_RS09115	COG0488	(ABC) transporter
NXV61_RS09120	COG3590	peptidase
NXV61_RS09125	COG0138	bifunctional purine biosynthesis protein purh
NXV61_RS09150	COG0772	Belongs to the SEDS family
NXV61_RS09160	COG1774	PSP1 C-terminal conserved region
NXV61_RS09165	COG0470	DNA polymerase III
NXV61_RS09170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXV61_RS09180	COG2193	ferroxidase activity
NXV61_RS09220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXV61_RS09225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXV61_RS09230	COG1160	GTP binding
NXV61_RS09240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXV61_RS09245	COG1127	ABC transporter
NXV61_RS09250	COG0724	RNA recognition motif
NXV61_RS09255	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXV61_RS09260	COG0740	serine-type endopeptidase activity
NXV61_RS09265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXV61_RS09270	COG0514	ATP-dependent DNA helicase (RecQ)
NXV61_RS09275	COG0516	GMP reductase activity
NXV61_RS09275	COG0517	IMP dehydrogenase activity
NXV61_RS09280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXV61_RS09290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXV61_RS09305	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXV61_RS09320	COG4771	TonB-dependent receptor
NXV61_RS09340	COG3537	Alpha-1,2-mannosidase
NXV61_RS09375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXV61_RS09385	COG3022	response to hydroperoxide
NXV61_RS09390	COG0110	maltose O-acetyltransferase activity
NXV61_RS09420	COG1187	pseudouridine synthase activity
NXV61_RS09425	COG0017	Asparaginyl-tRNA synthetase
NXV61_RS09435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXV61_RS09440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXV61_RS09445	COG0052	Belongs to the universal ribosomal protein uS2 family
NXV61_RS09450	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXV61_RS09465	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXV61_RS09470	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXV61_RS09475	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXV61_RS09495	COG0482	sulfurtransferase activity
NXV61_RS09505	COG1570	exodeoxyribonuclease VII activity
NXV61_RS09515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXV61_RS09525	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXV61_RS09530	COG0489	protein tyrosine kinase activity
NXV61_RS09535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV61_RS09565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS09585	COG0714	Associated with various cellular activities
NXV61_RS09590	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXV61_RS09595	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NXV61_RS09600	COG0039	L-malate dehydrogenase activity
NXV61_RS09620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXV61_RS09625	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXV61_RS09630	COG0811	peptide transport
NXV61_RS09635	COG0848	biopolymer transport protein
NXV61_RS09650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXV61_RS09655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXV61_RS09660	COG0105	UTP biosynthetic process
NXV61_RS09665	COG0739	heme binding
NXV61_RS09680	COG0149	triose-phosphate isomerase activity
NXV61_RS09690	COG0302	gtp cyclohydrolase
NXV61_RS09695	COG0358	DNA primase activity
NXV61_RS09705	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXV61_RS09710	COG0436	Aminotransferase
NXV61_RS09730	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NXV61_RS09730	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NXV61_RS09745	COG0009	L-threonylcarbamoyladenylate synthase
NXV61_RS09755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXV61_RS09760	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXV61_RS09765	COG0658	competence protein
NXV61_RS09765	COG2333	competence protein COMEC
NXV61_RS09770	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXV61_RS09780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXV61_RS09790	COG4771	TonB-dependent receptor
NXV61_RS09815	COG0745	RESPONSE REGULATOR receiver
NXV61_RS09815	COG2205	protein histidine kinase activity
NXV61_RS09815	COG3292	Two component regulator propeller
NXV61_RS09820	COG4771	TonB-dependent receptor
NXV61_RS09850	COG3537	Alpha-1,2-mannosidase
NXV61_RS09860	COG3537	Alpha-1,2-mannosidase
NXV61_RS09865	COG3279	Response regulator of the LytR AlgR family
NXV61_RS09870	COG3275	phosphorelay sensor kinase activity
NXV61_RS09875	COG1566	PFAM secretion protein HlyD family protein
NXV61_RS09890	COG0386	Belongs to the glutathione peroxidase family
NXV61_RS09895	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NXV61_RS09900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXV61_RS09905	COG1203	CRISPR-associated helicase, Cas3
NXV61_RS09930	COG1518	maintenance of DNA repeat elements
NXV61_RS09935	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NXV61_RS09980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXV61_RS10025	COG4771	TonB-dependent receptor
NXV61_RS10030	COG0702	epimerase
NXV61_RS10040	COG4124	Belongs to the glycosyl hydrolase 26 family
NXV61_RS10075	COG2207	Transcriptional regulator
NXV61_RS10095	COG0702	epimerase
NXV61_RS10100	COG4771	TonB-dependent receptor
NXV61_RS10105	COG0745	RESPONSE REGULATOR receiver
NXV61_RS10105	COG2205	protein histidine kinase activity
NXV61_RS10105	COG4191	Histidine kinase
NXV61_RS10110	COG3119	arylsulfatase activity
NXV61_RS10115	COG5002	protein histidine kinase activity
NXV61_RS10120	COG1629	transport
NXV61_RS10125	COG0702	epimerase
NXV61_RS10165	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS10170	COG5434	Belongs to the glycosyl hydrolase 28 family
NXV61_RS10185	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS10195	COG2314	TM2 domain
NXV61_RS10235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXV61_RS10250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXV61_RS10255	COG0742	ribosomal rna small subunit methyltransferase
NXV61_RS10270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV61_RS10310	COG3537	Alpha-1,2-mannosidase
NXV61_RS10315	COG3537	Alpha-1,2-mannosidase
NXV61_RS10335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXV61_RS10340	COG0739	heme binding
NXV61_RS10350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXV61_RS10355	COG0741	lytic transglycosylase activity
NXV61_RS10355	COG1388	LysM domain
NXV61_RS10365	COG1475	DNA binding
NXV61_RS10370	COG1192	Involved in chromosome partitioning
NXV61_RS10380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV61_RS10390	COG4589	Belongs to the CDS family
NXV61_RS10395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXV61_RS10400	COG0799	negative regulation of ribosome biogenesis
NXV61_RS10410	COG0702	epimerase
NXV61_RS10415	COG1629	transport
NXV61_RS10415	COG4206	TonB-dependent receptor
NXV61_RS10425	COG1196	nuclear chromosome segregation
NXV61_RS10430	COG2239	Acts as a magnesium transporter
NXV61_RS10435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXV61_RS10445	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV61_RS10480	COG1119	ATPase activity
NXV61_RS10490	COG0668	transmembrane transport
NXV61_RS10495	COG0662	Cupin 2, conserved barrel domain protein
NXV61_RS10495	COG2207	Transcriptional regulator
NXV61_RS10520	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV61_RS10525	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXV61_RS10530	COG0713	ATP synthesis coupled electron transport
NXV61_RS10545	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXV61_RS10550	COG0649	NAD binding
NXV61_RS10550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV61_RS10555	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV61_RS10560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXV61_RS10590	COG3250	beta-galactosidase activity
NXV61_RS10615	COG0657	acetylesterase activity
NXV61_RS10615	COG2755	lipolytic protein G-D-S-L family
NXV61_RS10660	COG0702	epimerase
NXV61_RS10675	COG4771	TonB-dependent receptor
NXV61_RS10685	COG1629	transport
NXV61_RS10685	COG4206	TonB-dependent receptor
NXV61_RS10700	COG3537	Alpha-1,2-mannosidase
NXV61_RS10720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXV61_RS10725	COG0569	domain protein
NXV61_RS10730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXV61_RS10740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXV61_RS10745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXV61_RS10750	COG0805	protein transport
NXV61_RS10760	COG2271	Major facilitator Superfamily
NXV61_RS10765	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXV61_RS10770	COG3775	system Galactitol-specific IIC component
NXV61_RS10785	COG2755	lipolytic protein G-D-S-L family
NXV61_RS10790	COG3292	Two component regulator propeller
NXV61_RS10790	COG0745	RESPONSE REGULATOR receiver
NXV61_RS10790	COG2205	protein histidine kinase activity
NXV61_RS10800	COG0702	epimerase
NXV61_RS10805	COG4771	TonB-dependent receptor
NXV61_RS10825	COG3279	Response regulator of the LytR AlgR family
NXV61_RS10845	COG4206	TonB-dependent receptor
NXV61_RS10845	COG1629	transport
NXV61_RS10860	COG2205	protein histidine kinase activity
NXV61_RS10860	COG0745	RESPONSE REGULATOR receiver
NXV61_RS10860	COG3292	Two component regulator propeller
NXV61_RS10865	COG1242	4 iron, 4 sulfur cluster binding
NXV61_RS10875	COG0363	glucosamine-6-phosphate deaminase activity
NXV61_RS10880	COG0009	L-threonylcarbamoyladenylate synthase
NXV61_RS10890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV61_RS10895	COG0561	phosphatase activity
NXV61_RS10900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXV61_RS10905	COG1408	metallophosphoesterase
NXV61_RS10935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXV61_RS10960	COG2755	lipolytic protein G-D-S-L family
NXV61_RS10990	COG3401	FG-GAP repeat protein
NXV61_RS10995	COG3250	beta-galactosidase activity
NXV61_RS11005	COG3345	alpha-galactosidase
NXV61_RS11040	COG4771	TonB-dependent receptor
NXV61_RS11045	COG0702	epimerase
NXV61_RS11060	COG4771	TonB-dependent receptor
NXV61_RS11085	COG2755	lipolytic protein G-D-S-L family
NXV61_RS11095	COG3401	FG-GAP repeat protein
NXV61_RS11105	COG3254	rhamnose metabolic process
NXV61_RS11110	COG2205	protein histidine kinase activity
NXV61_RS11110	COG3292	Two component regulator propeller
NXV61_RS11110	COG2205	protein histidine kinase activity
NXV61_RS11110	COG0745	RESPONSE REGULATOR receiver
NXV61_RS11110	COG3292	Two component regulator propeller
NXV61_RS11110	COG0745	RESPONSE REGULATOR receiver
NXV61_RS11125	COG3250	beta-galactosidase activity
NXV61_RS11130	COG3292	Two component regulator propeller
NXV61_RS11130	COG2205	protein histidine kinase activity
NXV61_RS11130	COG0745	RESPONSE REGULATOR receiver
NXV61_RS11135	COG4733	cellulase activity
NXV61_RS11140	COG0546	phosphoglycolate phosphatase activity
NXV61_RS11160	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXV61_RS11170	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXV61_RS11180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXV61_RS11185	COG0823	Involved in the tonB-independent uptake of proteins
NXV61_RS11185	COG1506	peptidase
NXV61_RS11230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXV61_RS11245	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXV61_RS11245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXV61_RS11250	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXV61_RS11260	COG0284	orotidine-5'-phosphate decarboxylase activity
NXV61_RS11265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXV61_RS11275	COG1704	LemA family
NXV61_RS11290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXV61_RS11295	COG2226	methyltransferase
NXV61_RS11300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXV61_RS11305	COG1702	phosphate starvation-inducible protein PhoH
NXV61_RS11390	COG2205	protein histidine kinase activity
NXV61_RS11390	COG0745	RESPONSE REGULATOR receiver
NXV61_RS11390	COG3292	Two component regulator propeller
NXV61_RS11395	COG0101	tRNA pseudouridine synthase activity
NXV61_RS11415	COG3250	beta-galactosidase activity
NXV61_RS11420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXV61_RS11425	COG0673	inositol 2-dehydrogenase activity
NXV61_RS11445	COG4771	TonB-dependent receptor
NXV61_RS11465	COG5434	Belongs to the glycosyl hydrolase 28 family
NXV61_RS11470	COG0673	inositol 2-dehydrogenase activity
NXV61_RS11485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXV61_RS11495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXV61_RS11505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NXV61_RS11510	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXV61_RS11515	COG0793	Belongs to the peptidase S41A family
NXV61_RS11520	COG2131	deaminase
NXV61_RS11530	COG0339	signal peptide processing
NXV61_RS11540	COG1970	mechanosensitive ion channel activity
NXV61_RS11545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXV61_RS11545	COG0519	Catalyzes the synthesis of GMP from XMP
NXV61_RS11620	COG4771	TonB-dependent receptor
NXV61_RS11650	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS11665	COG0297	glycogen (starch) synthase activity
NXV61_RS11670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXV61_RS11675	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXV61_RS11680	COG0543	2 iron, 2 sulfur cluster binding
NXV61_RS11690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXV61_RS11695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXV61_RS11700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXV61_RS11715	COG0791	NLP P60 protein
NXV61_RS11730	COG0612	Peptidase, M16
NXV61_RS11735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXV61_RS11740	COG1597	lipid kinase activity
NXV61_RS11745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXV61_RS11760	COG1136	(ABC) transporter
NXV61_RS11780	COG2211	Major facilitator Superfamily
NXV61_RS11785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXV61_RS11800	COG1674	ftsk spoiiie
NXV61_RS11810	COG0492	ferredoxin-NADP+ reductase activity
NXV61_RS11815	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS11845	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV61_RS11845	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV61_RS11875	COG3956	TIGRFAM MazG family protein
NXV61_RS11890	COG0525	valine-tRNA ligase activity
NXV61_RS11895	COG0784	Response regulator, receiver
NXV61_RS11895	COG2205	protein histidine kinase activity
NXV61_RS11895	COG2198	Histidine kinase
NXV61_RS11910	COG4206	TonB-dependent receptor
NXV61_RS11910	COG1629	transport
NXV61_RS11935	COG0653	protein targeting
NXV61_RS11940	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXV61_RS11955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXV61_RS11975	COG1253	flavin adenine dinucleotide binding
NXV61_RS11985	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXV61_RS11995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXV61_RS12000	COG2204	response regulator
NXV61_RS12040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXV61_RS12040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXV61_RS12055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXV61_RS12060	COG0563	adenylate kinase activity
NXV61_RS12065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXV61_RS12070	COG1496	oxidoreductase activity
NXV61_RS12085	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS12090	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS12105	COG0477	Major facilitator Superfamily
NXV61_RS12105	COG2814	Major facilitator Superfamily
NXV61_RS12110	COG0457	Tetratricopeptide repeat
NXV61_RS12115	COG2706	6-phosphogluconolactonase activity
NXV61_RS12235	COG5290	Psort location Cytoplasmic, score
NXV61_RS12295	COG4206	TonB-dependent receptor
NXV61_RS12295	COG1629	transport
NXV61_RS12360	COG3142	Participates in the control of copper homeostasis
NXV61_RS12365	COG1418	mRNA catabolic process
NXV61_RS12395	COG1070	Carbohydrate kinase
NXV61_RS12400	COG1063	alcohol dehydrogenase
NXV61_RS12405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXV61_RS12430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXV61_RS12430	COG1333	cytochrome c biogenesis protein
NXV61_RS12470	COG0673	inositol 2-dehydrogenase activity
NXV61_RS12480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXV61_RS12485	COG2832	Protein of unknown function (DUF454)
NXV61_RS12495	COG0602	queuosine metabolic process
NXV61_RS12500	COG0247	lactate metabolic process
NXV61_RS12505	COG1139	Iron-sulfur cluster binding protein
NXV61_RS12515	COG0351	phosphomethylpyrimidine kinase
NXV61_RS12540	COG4589	Belongs to the CDS family
NXV61_RS12550	COG2304	oxidoreductase activity
NXV61_RS12570	COG1393	Belongs to the ArsC family
NXV61_RS12580	COG1629	transport
NXV61_RS12580	COG4206	TonB-dependent receptor
NXV61_RS12595	COG2233	PERMEase
NXV61_RS12600	COG1509	lysine 2,3-aminomutase activity
NXV61_RS12610	COG1115	amino acid carrier protein
NXV61_RS12650	COG1285	pathogenesis
NXV61_RS12660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXV61_RS12665	COG0741	lytic transglycosylase activity
NXV61_RS12665	COG1388	LysM domain
NXV61_RS12735	COG0564	pseudouridine synthase activity
NXV61_RS12760	COG0346	lactoylglutathione lyase activity
NXV61_RS12770	COG0653	protein targeting
NXV61_RS12790	COG1063	alcohol dehydrogenase
NXV61_RS12820	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NXV61_RS12825	COG4804	nuclease activity
NXV61_RS12830	COG0732	type I restriction modification DNA specificity domain
NXV61_RS12855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXV61_RS12860	COG0784	Response regulator, receiver
NXV61_RS12860	COG5002	protein histidine kinase activity
NXV61_RS12865	COG2910	NAD(P)H-binding
NXV61_RS12875	COG4864	UPF0365 protein
NXV61_RS12890	COG0037	tRNA processing
NXV61_RS12920	COG0463	Glycosyl transferase, family 2
NXV61_RS12945	COG1595	DNA-templated transcription, initiation
NXV61_RS12950	COG0148	phosphopyruvate hydratase activity
NXV61_RS12960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXV61_RS12975	COG1082	Xylose isomerase domain protein TIM barrel
NXV61_RS12980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXV61_RS12985	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV61_RS12990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXV61_RS13005	COG4651	solute:proton antiporter activity
NXV61_RS13005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXV61_RS13015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXV61_RS13020	COG0193	aminoacyl-tRNA hydrolase activity
NXV61_RS13035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXV61_RS13040	COG1862	Preprotein translocase
NXV61_RS13050	COG0237	dephospho-CoA kinase activity
NXV61_RS13065	COG0542	response to heat
NXV61_RS13080	COG0583	DNA-binding transcription factor activity
NXV61_RS13165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXV61_RS13170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXV61_RS13190	COG0443	Heat shock 70 kDa protein
NXV61_RS13200	COG4974	Belongs to the 'phage' integrase family
NXV61_RS13240	COG4974	Belongs to the 'phage' integrase family
NXV61_RS13255	COG0732	type I restriction modification DNA specificity domain
NXV61_RS13300	COG1074	ATP-dependent DNA helicase activity
NXV61_RS13310	COG1205	dead DEAH box helicase
NXV61_RS13310	COG1111	helicase
NXV61_RS13310	COG1205	dead DEAH box helicase
NXV61_RS13310	COG1111	helicase
NXV61_RS13315	COG3177	Filamentation induced by cAMP protein fic
NXV61_RS13335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXV61_RS13340	COG0306	phosphate transporter
NXV61_RS13350	COG0586	Pfam SNARE associated Golgi protein
NXV61_RS13405	COG0038	chloride channel
NXV61_RS13410	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXV61_RS13430	COG3119	arylsulfatase activity
NXV61_RS13440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV61_RS13445	COG0702	epimerase
NXV61_RS13450	COG4771	TonB-dependent receptor
NXV61_RS13460	COG5434	Belongs to the glycosyl hydrolase 28 family
NXV61_RS13465	COG3292	Two component regulator propeller
NXV61_RS13465	COG2205	protein histidine kinase activity
NXV61_RS13465	COG0745	RESPONSE REGULATOR receiver
NXV61_RS13470	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXV61_RS13475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXV61_RS13495	COG4935	Belongs to the peptidase S8 family
NXV61_RS13495	COG1404	Belongs to the peptidase S8 family
NXV61_RS13545	COG0156	8-amino-7-oxononanoate synthase activity
NXV61_RS13555	COG0156	8-amino-7-oxononanoate synthase activity
NXV61_RS13570	COG3250	beta-galactosidase activity
NXV61_RS13585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV61_RS13590	COG1629	transport
NXV61_RS13590	COG4206	TonB-dependent receptor
NXV61_RS13600	COG3292	Two component regulator propeller
NXV61_RS13600	COG2205	protein histidine kinase activity
NXV61_RS13600	COG0745	RESPONSE REGULATOR receiver
NXV61_RS13625	COG1760	l-serine dehydratase
NXV61_RS13630	COG0598	Magnesium transport protein CorA
NXV61_RS13635	COG1193	negative regulation of DNA recombination
NXV61_RS13670	COG0358	DNA primase activity
NXV61_RS13705	COG1629	transport
NXV61_RS13705	COG4206	TonB-dependent receptor
NXV61_RS13720	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS13735	COG3250	beta-galactosidase activity
NXV61_RS13745	COG1629	transport
NXV61_RS13760	COG0668	transmembrane transport
NXV61_RS13765	COG1523	belongs to the glycosyl hydrolase 13 family
NXV61_RS13775	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXV61_RS13785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS13795	COG1538	Outer membrane efflux protein
NXV61_RS13805	COG0456	acetyltransferase
NXV61_RS13820	COG0561	phosphatase activity
NXV61_RS13825	COG1169	isochorismate synthase
NXV61_RS13830	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXV61_RS13835	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXV61_RS13840	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS13860	COG1629	transport
NXV61_RS13860	COG4206	TonB-dependent receptor
NXV61_RS13900	COG0783	Belongs to the Dps family
NXV61_RS13905	COG0583	DNA-binding transcription factor activity
NXV61_RS13915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXV61_RS13935	COG1595	DNA-templated transcription, initiation
NXV61_RS13950	COG4771	TonB-dependent receptor
NXV61_RS13960	COG0584	glycerophosphoryl diester phosphodiesterase
NXV61_RS13965	COG0584	glycerophosphoryl diester phosphodiesterase
NXV61_RS14025	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS14030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXV61_RS14035	COG1882	Formate acetyltransferase
NXV61_RS14095	COG0358	DNA primase activity
NXV61_RS14125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXV61_RS14165	COG3292	Two component regulator propeller
NXV61_RS14165	COG0745	RESPONSE REGULATOR receiver
NXV61_RS14165	COG2205	protein histidine kinase activity
NXV61_RS14175	COG1595	DNA-templated transcription, initiation
NXV61_RS14210	COG4771	TonB-dependent receptor
NXV61_RS14215	COG0702	epimerase
NXV61_RS14240	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS14245	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS14255	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXV61_RS14285	COG1595	DNA-templated transcription, initiation
NXV61_RS14290	COG1629	transport
NXV61_RS14290	COG4206	TonB-dependent receptor
NXV61_RS14335	COG1595	DNA-templated transcription, initiation
NXV61_RS14340	COG4206	TonB-dependent receptor
NXV61_RS14340	COG1629	transport
NXV61_RS14360	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS14370	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV61_RS14380	COG1253	flavin adenine dinucleotide binding
NXV61_RS14385	COG0501	Belongs to the peptidase M48B family
NXV61_RS14410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXV61_RS14415	COG0482	sulfurtransferase activity
NXV61_RS14420	COG2197	response regulator
NXV61_RS14430	COG1757	Na H antiporter
NXV61_RS14445	COG2814	Major facilitator Superfamily
NXV61_RS14450	COG4953	penicillin-binding protein 1C
NXV61_RS14455	COG2373	Large extracellular alpha-helical protein
NXV61_RS14460	COG0545	Peptidyl-prolyl cis-trans isomerase
NXV61_RS14545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXV61_RS14550	COG0646	methionine synthase
NXV61_RS14550	COG1410	methionine synthase
NXV61_RS14555	COG0778	Nitroreductase
NXV61_RS14560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXV61_RS14570	COG0572	uridine kinase
NXV61_RS14580	COG4232	protein-disulfide reductase activity
NXV61_RS14585	COG1741	Belongs to the pirin family
NXV61_RS14600	COG1629	transport
NXV61_RS14605	COG0702	epimerase
NXV61_RS14635	COG2271	Major facilitator Superfamily
NXV61_RS14640	COG2271	Major facilitator Superfamily
NXV61_RS14660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXV61_RS14665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXV61_RS14670	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXV61_RS14675	COG0131	Imidazoleglycerol-phosphate dehydratase
NXV61_RS14685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXV61_RS14685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV61_RS14690	COG4771	TonB-dependent receptor
NXV61_RS14720	COG1404	Belongs to the peptidase S8 family
NXV61_RS14740	COG1592	Rubrerythrin
NXV61_RS14740	COG1773	rubredoxin
NXV61_RS14770	COG3591	Belongs to the peptidase S1B family
NXV61_RS14775	COG3591	Belongs to the peptidase S1B family
NXV61_RS14780	COG0641	radical SAM
NXV61_RS14810	COG0420	3'-5' exonuclease activity
NXV61_RS14835	COG0646	methionine synthase
NXV61_RS14835	COG1410	methionine synthase
NXV61_RS14845	COG0463	Glycosyl transferase, family 2
NXV61_RS14860	COG1032	radical SAM domain protein
NXV61_RS14885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV61_RS14920	COG0745	RESPONSE REGULATOR receiver
NXV61_RS14920	COG2205	protein histidine kinase activity
NXV61_RS14920	COG3292	Two component regulator propeller
NXV61_RS14925	COG3292	Two component regulator propeller
NXV61_RS14925	COG2205	protein histidine kinase activity
NXV61_RS14925	COG0745	RESPONSE REGULATOR receiver
NXV61_RS14930	COG1629	transport
NXV61_RS14940	COG0702	epimerase
NXV61_RS14955	COG4771	TonB-dependent receptor
NXV61_RS15025	COG0811	peptide transport
NXV61_RS15030	COG0848	biopolymer transport protein
NXV61_RS15080	COG1131	(ABC) transporter
NXV61_RS15115	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXV61_RS15160	COG0022	dehydrogenase e1 component
NXV61_RS15170	COG2264	protein methyltransferase activity
NXV61_RS15185	COG4206	TonB-dependent receptor
NXV61_RS15185	COG1629	transport
NXV61_RS15200	COG0590	tRNA wobble adenosine to inosine editing
NXV61_RS15205	COG0673	inositol 2-dehydrogenase activity
NXV61_RS15230	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXV61_RS15270	COG0714	Associated with various cellular activities
NXV61_RS15275	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXV61_RS15290	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS15295	COG5012	cobalamin binding
NXV61_RS15315	COG0698	ribose 5-phosphate isomerase
NXV61_RS15320	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NXV61_RS15335	COG1070	Carbohydrate kinase
NXV61_RS15340	COG2160	L-arabinose isomerase activity
NXV61_RS15370	COG0702	epimerase
NXV61_RS15375	COG4206	TonB-dependent receptor
NXV61_RS15375	COG1629	transport
NXV61_RS15385	COG1629	transport
NXV61_RS15385	COG4206	TonB-dependent receptor
NXV61_RS15395	COG2205	protein histidine kinase activity
NXV61_RS15395	COG3292	Two component regulator propeller
NXV61_RS15395	COG0745	RESPONSE REGULATOR receiver
NXV61_RS15400	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV61_RS15410	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV61_RS15415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXV61_RS15430	COG1482	cell wall glycoprotein biosynthetic process
NXV61_RS15465	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXV61_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS15480	COG1216	Glycosyl transferase, family 2
NXV61_RS15485	COG0463	Glycosyl transferase, family 2
NXV61_RS15510	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS15515	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXV61_RS15520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXV61_RS15540	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS15580	COG4221	oxidoreductase activity
NXV61_RS15595	COG3273	potassium ion transport
NXV61_RS15595	COG0471	metal ion transport
NXV61_RS15600	COG0529	Catalyzes the synthesis of activated sulfate
NXV61_RS15605	COG0175	sulfate reduction
NXV61_RS15610	COG2895	sulfate adenylyltransferase (ATP) activity
NXV61_RS15630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXV61_RS15635	COG0242	peptide deformylase activity
NXV61_RS15645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXV61_RS15650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXV61_RS15655	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXV61_RS15660	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXV61_RS15670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXV61_RS15675	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXV61_RS15690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXV61_RS15705	COG1940	carbohydrate kinase activity
NXV61_RS15710	COG2081	HI0933 family
NXV61_RS15730	COG4771	TonB-dependent receptor
NXV61_RS15765	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXV61_RS15765	COG2755	lipolytic protein G-D-S-L family
NXV61_RS15815	COG4771	TonB-dependent receptor
NXV61_RS15840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS15845	COG0657	acetylesterase activity
NXV61_RS15845	COG2755	lipolytic protein G-D-S-L family
NXV61_RS15855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS15860	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS15865	COG3250	beta-galactosidase activity
NXV61_RS15885	COG1091	dTDP-4-dehydrorhamnose reductase activity
NXV61_RS15915	COG1216	Glycosyl transferase, family 2
NXV61_RS15925	COG1216	Glycosyl transferase, family 2
NXV61_RS15950	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS15975	COG1629	transport
NXV61_RS15980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXV61_RS15985	COG0484	heat shock protein binding
NXV61_RS15990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXV61_RS15995	COG0488	(ABC) transporter
NXV61_RS16090	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS16135	COG2183	response to ionizing radiation
NXV61_RS16140	COG2205	protein histidine kinase activity
NXV61_RS16140	COG2202	Pas domain
NXV61_RS16145	COG0737	Belongs to the 5'-nucleotidase family
NXV61_RS16190	COG2985	domain, Protein
NXV61_RS16190	COG0490	domain, Protein
NXV61_RS16195	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXV61_RS16205	COG0318	PFAM AMP-dependent synthetase and ligase
NXV61_RS16210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS16215	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXV61_RS16220	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NXV61_RS16225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXV61_RS16235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXV61_RS16245	COG2837	iron assimilation
NXV61_RS16250	COG2135	peptidase activity
NXV61_RS16265	COG3279	Response regulator of the LytR AlgR family
NXV61_RS16275	COG0577	efflux transmembrane transporter activity
NXV61_RS16275	COG1136	(ABC) transporter
NXV61_RS16280	COG1136	(ABC) transporter
NXV61_RS16285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS16310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXV61_RS16320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXV61_RS16345	COG0501	Belongs to the peptidase M48B family
NXV61_RS16350	COG1704	LemA family
NXV61_RS16365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXV61_RS16370	COG2885	chlorophyll binding
NXV61_RS16375	COG0534	Mate efflux family protein
NXV61_RS16380	COG2755	lipolytic protein G-D-S-L family
NXV61_RS16380	COG0657	acetylesterase activity
NXV61_RS16390	COG1162	GTPase activity
NXV61_RS16410	COG0488	(ABC) transporter
NXV61_RS16440	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS16445	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS16450	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS16455	COG1442	glycosyl transferase family 8
NXV61_RS16465	COG2244	polysaccharide biosynthetic process
NXV61_RS16470	COG1442	glycosyl transferase family 8
NXV61_RS16470	COG1216	Glycosyl transferase, family 2
NXV61_RS16510	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS16520	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS16555	COG1805	sodium ion transport
NXV61_RS16560	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXV61_RS16570	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXV61_RS16575	COG2871	sodium ion transport
NXV61_RS16580	COG0513	Belongs to the DEAD box helicase family
NXV61_RS16585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXV61_RS16600	COG1739	Uncharacterized protein family UPF0029
NXV61_RS16615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXV61_RS16615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXV61_RS16620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXV61_RS16625	COG0357	Ribosomal RNA small subunit methyltransferase G
NXV61_RS16670	COG2217	Heavy metal translocating P-type atpase
NXV61_RS16680	COG0321	lipoyl(octanoyl) transferase activity
NXV61_RS16710	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXV61_RS16720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXV61_RS16735	COG1678	Uncharacterized ACR, COG1678
NXV61_RS16750	COG4974	Belongs to the 'phage' integrase family
NXV61_RS16760	COG0489	protein tyrosine kinase activity
NXV61_RS17105	COG1690	Belongs to the RtcB family
NXV61_RS17310	COG3275	phosphorelay sensor kinase activity
NXV61_RS17345	COG1475	DNA binding
NXV61_RS17410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXV61_RS17430	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS17455	COG1629	transport
NXV61_RS17455	COG4206	TonB-dependent receptor
NXV61_RS17485	COG4771	TonB-dependent receptor
NXV61_RS17520	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXV61_RS17525	COG3537	Alpha-1,2-mannosidase
NXV61_RS17545	COG0702	epimerase
NXV61_RS17570	COG3408	Glycogen debranching enzyme
NXV61_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS17595	COG3408	Glycogen debranching enzyme
NXV61_RS17605	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXV61_RS17615	COG0167	dihydroorotate dehydrogenase activity
NXV61_RS17620	COG0657	acetylesterase activity
NXV61_RS17620	COG2755	lipolytic protein G-D-S-L family
NXV61_RS17665	COG0784	Response regulator, receiver
NXV61_RS17665	COG2205	protein histidine kinase activity
NXV61_RS17665	COG5002	protein histidine kinase activity
NXV61_RS17675	COG3250	beta-galactosidase activity
NXV61_RS17685	COG0784	Response regulator, receiver
NXV61_RS17685	COG2205	protein histidine kinase activity
NXV61_RS17695	COG3250	beta-galactosidase activity
NXV61_RS17700	COG0745	RESPONSE REGULATOR receiver
NXV61_RS17705	COG5002	protein histidine kinase activity
NXV61_RS17735	COG3250	beta-galactosidase activity
NXV61_RS17745	COG3292	Two component regulator propeller
NXV61_RS17745	COG0745	RESPONSE REGULATOR receiver
NXV61_RS17745	COG2205	protein histidine kinase activity
NXV61_RS17775	COG2966	Psort location CytoplasmicMembrane, score
NXV61_RS17790	COG0300	oxidoreductase activity
NXV61_RS17800	COG1011	Hydrolase
NXV61_RS17850	COG4206	TonB-dependent receptor
NXV61_RS17875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS17890	COG0442	prolyl-tRNA aminoacylation
NXV61_RS17895	COG0745	RESPONSE REGULATOR receiver
NXV61_RS17900	COG2205	protein histidine kinase activity
NXV61_RS17935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXV61_RS17945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXV61_RS17950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXV61_RS17965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXV61_RS17970	COG0776	regulation of translation
NXV61_RS17975	COG0776	regulation of translation
NXV61_RS17980	COG0714	Associated with various cellular activities
NXV61_RS18045	COG0326	Molecular chaperone. Has ATPase activity
NXV61_RS18070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXV61_RS18075	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXV61_RS18080	COG0336	Belongs to the RNA methyltransferase TrmD family
NXV61_RS18085	COG0167	dihydroorotate dehydrogenase activity
NXV61_RS18090	COG0543	2 iron, 2 sulfur cluster binding
NXV61_RS18105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXV61_RS18135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXV61_RS18155	COG1132	(ABC) transporter
NXV61_RS18185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXV61_RS18190	COG1597	lipid kinase activity
NXV61_RS18195	COG0156	8-amino-7-oxononanoate synthase activity
NXV61_RS18210	COG4771	TonB-dependent receptor
NXV61_RS18230	COG1136	(ABC) transporter
NXV61_RS18230	COG0577	efflux transmembrane transporter activity
NXV61_RS18245	COG1136	(ABC) transporter
NXV61_RS18265	COG3852	Histidine kinase
NXV61_RS18275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXV61_RS18290	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXV61_RS18295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXV61_RS18315	COG0560	Phosphoserine phosphatase
NXV61_RS18315	COG3830	Belongs to the UPF0237 family
NXV61_RS18320	COG0513	Belongs to the DEAD box helicase family
NXV61_RS18350	COG0246	Mannitol dehydrogenase
NXV61_RS18360	COG1904	glucuronate isomerase
NXV61_RS18690	COG0484	heat shock protein binding
NXV61_RS18730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXV61_RS18735	COG0756	dUTP diphosphatase activity
NXV61_RS18965	COG0587	DNA-directed DNA polymerase activity
NXV61_RS18975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV61_RS18980	COG0587	DNA-directed DNA polymerase activity
NXV61_RS19055	COG4974	Belongs to the 'phage' integrase family
NXV61_RS19070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXV61_RS19095	COG3015	lipoprotein NlpE involved in copper resistance
NXV61_RS19125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXV61_RS19140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXV61_RS19150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXV61_RS19160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXV61_RS19160	COG3153	acetyltransferase
NXV61_RS19165	COG2814	Major facilitator Superfamily
NXV61_RS19165	COG0477	Major facilitator Superfamily
NXV61_RS19170	COG2115	Belongs to the xylose isomerase family
NXV61_RS19185	COG0351	phosphomethylpyrimidine kinase
NXV61_RS19190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXV61_RS19195	COG0045	succinate-CoA ligase (ADP-forming) activity
NXV61_RS19200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXV61_RS19225	COG3279	Response regulator of the LytR AlgR family
NXV61_RS19260	COG2326	polyphosphate kinase activity
NXV61_RS19270	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXV61_RS19295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXV61_RS19310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXV61_RS19315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXV61_RS19355	COG0745	RESPONSE REGULATOR receiver
NXV61_RS19355	COG3292	Two component regulator propeller
NXV61_RS19355	COG2205	protein histidine kinase activity
NXV61_RS19370	COG3153	acetyltransferase
NXV61_RS19375	COG3250	beta-galactosidase activity
NXV61_RS19380	COG3119	arylsulfatase activity
NXV61_RS19415	COG2205	protein histidine kinase activity
NXV61_RS19420	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXV61_RS19435	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXV61_RS19455	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXV61_RS19470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXV61_RS19475	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXV61_RS19480	COG2985	domain, Protein
NXV61_RS19520	COG2207	Transcriptional regulator
NXV61_RS19535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS19545	COG2431	L-lysine efflux transmembrane transporter activity
NXV61_RS19550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXV61_RS19560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXV61_RS19565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXV61_RS19570	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV61_RS19575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXV61_RS19580	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV61_RS19585	COG0356	it plays a direct role in the translocation of protons across the membrane
NXV61_RS19595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXV61_RS19600	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXV61_RS19645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXV61_RS19665	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXV61_RS19675	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXV61_RS19685	COG0534	Mate efflux family protein
NXV61_RS19695	COG1136	(ABC) transporter
NXV61_RS19730	COG1151	hydroxylamine reductase activity
NXV61_RS19735	COG2233	PERMEase
NXV61_RS19740	COG3263	regulation of cellular component size
NXV61_RS19745	COG0318	PFAM AMP-dependent synthetase and ligase
NXV61_RS19750	COG1082	Xylose isomerase domain protein TIM barrel
NXV61_RS19755	COG0745	RESPONSE REGULATOR receiver
NXV61_RS19760	COG5002	protein histidine kinase activity
NXV61_RS19780	COG3118	belongs to the thioredoxin family
NXV61_RS19785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXV61_RS19830	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXV61_RS19850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS19860	COG0681	Belongs to the peptidase S26 family
NXV61_RS19935	COG5002	protein histidine kinase activity
NXV61_RS19945	COG0352	thiamine-phosphate diphosphorylase activity
NXV61_RS19950	COG2022	thiamine diphosphate biosynthetic process
NXV61_RS19955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXV61_RS19960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXV61_RS19965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXV61_RS19970	COG0352	thiamine-phosphate diphosphorylase activity
NXV61_RS19985	COG0574	Belongs to the PEP-utilizing enzyme family
NXV61_RS19985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXV61_RS19990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXV61_RS19995	COG0564	pseudouridine synthase activity
NXV61_RS20015	COG0024	Methionine aminopeptidase
NXV61_RS20035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXV61_RS20045	COG0481	GTPase activity
NXV61_RS20060	COG0708	Exodeoxyribonuclease III
NXV61_RS20075	COG0217	transcriptional regulatory protein
NXV61_RS20080	COG0072	phenylalanine-tRNA ligase activity
NXV61_RS20080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXV61_RS20085	COG0305	Participates in initiation and elongation during chromosome replication
NXV61_RS20090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXV61_RS20095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXV61_RS20100	COG4657	Part of a membrane complex involved in electron transport
NXV61_RS20105	COG4660	Part of a membrane complex involved in electron transport
NXV61_RS20110	COG4659	FMN binding
NXV61_RS20115	COG4658	electron transport chain
NXV61_RS20165	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS20185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXV61_RS20185	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS20225	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS20240	COG1086	Polysaccharide biosynthesis protein
NXV61_RS20295	COG0504	CTP synthase activity
NXV61_RS20300	COG0706	membrane insertase activity
NXV61_RS20305	COG0534	Mate efflux family protein
NXV61_RS20310	COG1506	peptidase
NXV61_RS20310	COG0823	Involved in the tonB-independent uptake of proteins
NXV61_RS20330	COG1983	PspC domain protein
NXV61_RS20335	COG1695	Transcriptional regulator
NXV61_RS20345	COG3104	oligopeptide transport
NXV61_RS20350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXV61_RS20360	COG1388	LysM domain
NXV61_RS20360	COG3942	CHAP domain
NXV61_RS20390	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXV61_RS20395	COG0556	nucleotide-excision repair
NXV61_RS20410	COG2949	membrane
NXV61_RS20415	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXV61_RS20425	COG0842	Transport permease protein
NXV61_RS20430	COG0842	Transport permease protein
NXV61_RS20435	COG1131	(ABC) transporter
NXV61_RS20450	COG2207	Transcriptional regulator
NXV61_RS20450	COG1917	Cupin 2, conserved barrel domain protein
NXV61_RS20460	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXV61_RS20465	COG0505	Belongs to the CarA family
NXV61_RS20475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXV61_RS20480	COG0067	glutamate synthase
NXV61_RS20480	COG0069	glutamate synthase activity
NXV61_RS20480	COG0070	glutamate synthase
NXV61_RS20490	COG0367	asparagine synthase
NXV61_RS20505	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXV61_RS20510	COG0436	Aminotransferase
NXV61_RS20520	COG0347	Belongs to the P(II) protein family
NXV61_RS20525	COG0004	ammonium transporteR
NXV61_RS20540	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXV61_RS20550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXV61_RS20555	COG0471	metal ion transport
NXV61_RS20555	COG0490	domain, Protein
NXV61_RS20565	COG1979	alcohol dehydrogenase
NXV61_RS20575	COG0133	tryptophan synthase activity
NXV61_RS20580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXV61_RS20590	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXV61_RS20595	COG0134	indole-3-glycerol-phosphate synthase activity
NXV61_RS20600	COG0135	phosphoribosylanthranilate isomerase activity
NXV61_RS20605	COG0159	tryptophan synthase activity
NXV61_RS20610	COG0252	asparaginase activity
NXV61_RS20620	COG2205	protein histidine kinase activity
NXV61_RS20620	COG3292	Two component regulator propeller
NXV61_RS20620	COG0745	RESPONSE REGULATOR receiver
NXV61_RS20625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXV61_RS20635	COG0110	maltose O-acetyltransferase activity
NXV61_RS20640	COG2197	response regulator
NXV61_RS20660	COG0716	FMN binding
NXV61_RS20680	COG3487	Iron-regulated protein
NXV61_RS20690	COG3746	phosphate-selective porin O and P
NXV61_RS20720	COG1132	(ABC) transporter
NXV61_RS20735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS20745	COG4771	TonB-dependent receptor
NXV61_RS20755	COG4771	TonB-dependent receptor
NXV61_RS20765	COG2985	domain, Protein
NXV61_RS20765	COG0490	domain, Protein
NXV61_RS20770	COG1230	cation diffusion facilitator family transporter
NXV61_RS20790	COG1609	Transcriptional regulator
NXV61_RS20795	COG2721	sulfolactate sulfo-lyase activity
NXV61_RS20865	COG3385	transposase activity
NXV61_RS20875	COG1733	regulation of RNA biosynthetic process
NXV61_RS20885	COG2205	protein histidine kinase activity
NXV61_RS20885	COG2198	Histidine kinase
NXV61_RS20885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXV61_RS20885	COG0784	Response regulator, receiver
NXV61_RS20895	COG3275	phosphorelay sensor kinase activity
NXV61_RS20920	COG0228	four-way junction DNA binding
NXV61_RS20925	COG2188	Transcriptional regulator
NXV61_RS20930	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXV61_RS20940	COG1070	Carbohydrate kinase
NXV61_RS20950	COG0738	Major facilitator superfamily
NXV61_RS21000	COG2207	Transcriptional regulator
NXV61_RS21020	COG1177	transmembrane transport
NXV61_RS21025	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXV61_RS21030	COG3842	ATPase activity
NXV61_RS21035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXV61_RS21050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXV61_RS21070	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXV61_RS21095	COG1725	Transcriptional regulator
NXV61_RS21105	COG1131	(ABC) transporter
NXV61_RS21165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXV61_RS21170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXV61_RS21175	COG4948	Mandelate Racemase Muconate Lactonizing
NXV61_RS21190	COG1295	ribonuclease BN
NXV61_RS21205	COG0704	Plays a role in the regulation of phosphate uptake
NXV61_RS21210	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXV61_RS21215	COG0581	inorganic phosphate transmembrane transporter activity
NXV61_RS21220	COG0573	inorganic phosphate transmembrane transporter activity
NXV61_RS21230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXV61_RS21240	COG0586	Pfam SNARE associated Golgi protein
NXV61_RS21250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXV61_RS21265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXV61_RS21270	COG0167	dihydroorotate dehydrogenase activity
NXV61_RS21275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXV61_RS21295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXV61_RS21315	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXV61_RS21320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS21340	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS21355	COG4974	Belongs to the 'phage' integrase family
NXV61_RS21510	COG1475	DNA binding
NXV61_RS21530	COG1192	Involved in chromosome partitioning
NXV61_RS21545	COG3292	Two component regulator propeller
NXV61_RS21545	COG2205	protein histidine kinase activity
NXV61_RS21545	COG0745	RESPONSE REGULATOR receiver
NXV61_RS21550	COG1501	Belongs to the glycosyl hydrolase 31 family
NXV61_RS21655	COG3344	reverse transcriptase
NXV61_RS21675	COG0582	viral genome integration into host DNA
NXV61_RS21755	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXV61_RS21760	COG1196	nuclear chromosome segregation
NXV61_RS21760	COG0741	lytic transglycosylase activity
NXV61_RS21760	COG0739	heme binding
NXV61_RS21820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXV61_RS21995	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS22000	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NXV61_RS22010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXV61_RS22010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS22025	COG0297	glycogen (starch) synthase activity
NXV61_RS22090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXV61_RS22095	COG0497	DNA recombination
NXV61_RS22110	COG0592	DNA-directed DNA polymerase activity
NXV61_RS22125	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXV61_RS22125	COG0321	lipoyl(octanoyl) transferase activity
NXV61_RS22130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXV61_RS22140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXV61_RS22145	COG0156	8-amino-7-oxononanoate synthase activity
NXV61_RS22155	COG5002	protein histidine kinase activity
NXV61_RS22170	COG0019	diaminopimelate decarboxylase activity
NXV61_RS22175	COG0527	aspartate kinase activity
NXV61_RS22180	COG2884	Cell division ATP-binding protein ftsE
NXV61_RS22185	COG0140	phosphoribosyl-ATP diphosphatase activity
NXV61_RS22185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXV61_RS22190	COG0107	imidazoleglycerol-phosphate synthase activity
NXV61_RS22195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXV61_RS22200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXV61_RS22205	COG0788	formyltetrahydrofolate deformylase activity
NXV61_RS22385	COG5410	chromosome segregation
NXV61_RS22445	COG0629	single-stranded DNA binding
NXV61_RS22475	COG0085	RNA polymerase activity
NXV61_RS22510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXV61_RS22570	COG0693	protein deglycase activity
NXV61_RS22605	COG1073	alpha beta
NXV61_RS22615	COG0656	L-ascorbic acid biosynthetic process
NXV61_RS22640	COG2076	Multidrug Resistance protein
NXV61_RS22690	COG3546	catalase activity
NXV61_RS22720	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXV61_RS22735	COG2814	Major facilitator Superfamily
NXV61_RS22745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXV61_RS22760	COG1309	transcriptional regulator
NXV61_RS22785	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXV61_RS22790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NXV61_RS22805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXV61_RS22815	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXV61_RS22830	COG4771	TonB-dependent receptor
NXV61_RS22905	COG1312	Catalyzes the dehydration of D-mannonate
NXV61_RS22910	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS22915	COG1609	Transcriptional regulator
NXV61_RS22930	COG1929	Belongs to the glycerate kinase type-1 family
NXV61_RS22935	COG2223	nitrite transmembrane transporter activity
NXV61_RS22955	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXV61_RS22955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXV61_RS22970	COG2226	methyltransferase
NXV61_RS22980	COG0784	Response regulator, receiver
NXV61_RS22980	COG5002	protein histidine kinase activity
NXV61_RS22985	COG0511	ligase activity, forming carbon-carbon bonds
NXV61_RS22990	COG0439	Biotin carboxylase
NXV61_RS22995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV61_RS23010	COG1620	l-lactate permease
NXV61_RS23015	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NXV61_RS23020	COG1690	Belongs to the RtcB family
NXV61_RS23055	COG0110	maltose O-acetyltransferase activity
NXV61_RS23065	COG0577	efflux transmembrane transporter activity
NXV61_RS23070	COG0577	efflux transmembrane transporter activity
NXV61_RS23070	COG1136	(ABC) transporter
NXV61_RS23095	COG0628	permease
NXV61_RS23100	COG1215	transferase activity, transferring glycosyl groups
NXV61_RS23110	COG0189	ligase activity
NXV61_RS23110	COG0569	domain protein
NXV61_RS23115	COG0577	efflux transmembrane transporter activity
NXV61_RS23115	COG1136	(ABC) transporter
NXV61_RS23120	COG0436	Aminotransferase
NXV61_RS23135	COG0488	(ABC) transporter
NXV61_RS23150	COG0745	RESPONSE REGULATOR receiver
NXV61_RS23155	COG5002	protein histidine kinase activity
NXV61_RS23200	COG3033	Beta-eliminating lyase
NXV61_RS23225	COG0629	single-stranded DNA binding
NXV61_RS23230	COG1194	a g-specific adenine glycosylase
NXV61_RS23240	COG1530	ribonuclease E activity
NXV61_RS23245	COG2885	chlorophyll binding
NXV61_RS23285	COG4974	Belongs to the 'phage' integrase family
NXV61_RS23290	COG4974	Belongs to the 'phage' integrase family
NXV61_RS23360	COG1629	transport
NXV61_RS23370	COG1192	Involved in chromosome partitioning
NXV61_RS23395	COG1120	ATPase activity
NXV61_RS23400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXV61_RS23460	COG0305	Participates in initiation and elongation during chromosome replication
NXV61_RS23475	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS23495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXV61_RS23505	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXV61_RS23520	COG4191	Histidine kinase
NXV61_RS23525	COG2204	response regulator
NXV61_RS23535	COG2205	protein histidine kinase activity
NXV61_RS23535	COG5002	protein histidine kinase activity
NXV61_RS23535	COG0784	Response regulator, receiver
NXV61_RS23555	COG1136	(ABC) transporter
NXV61_RS23565	COG1252	NADH dehydrogenase
NXV61_RS23570	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXV61_RS23585	COG3059	membrane
NXV61_RS23590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXV61_RS23595	COG2205	protein histidine kinase activity
NXV61_RS23595	COG3292	Two component regulator propeller
NXV61_RS23595	COG0745	RESPONSE REGULATOR receiver
NXV61_RS23605	COG3250	beta-galactosidase activity
NXV61_RS23610	COG0488	(ABC) transporter
NXV61_RS23640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXV61_RS23650	COG0739	heme binding
NXV61_RS23655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NXV61_RS23660	COG4206	TonB-dependent receptor
NXV61_RS23660	COG1629	transport
NXV61_RS23670	COG0686	Belongs to the AlaDH PNT family
NXV61_RS23720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXV61_RS23740	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXV61_RS23745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXV61_RS23785	COG1595	DNA-templated transcription, initiation
NXV61_RS23800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXV61_RS23805	COG1741	Belongs to the pirin family
NXV61_RS23810	COG0259	pyridoxamine-phosphate oxidase activity
NXV61_RS23935	COG0358	DNA primase activity
NXV61_RS24205	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXV61_RS24205	COG1918	ferrous iron import across plasma membrane
NXV61_RS24210	COG0037	tRNA processing
NXV61_RS24225	COG3119	arylsulfatase activity
NXV61_RS24235	COG2205	protein histidine kinase activity
NXV61_RS24240	COG0534	Mate efflux family protein
NXV61_RS24245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXV61_RS24260	COG1858	cytochrome C peroxidase
NXV61_RS24270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXV61_RS24285	COG1983	PspC domain protein
NXV61_RS24290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXV61_RS24315	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXV61_RS24335	COG4206	TonB-dependent receptor
NXV61_RS24335	COG1629	transport
NXV61_RS24350	COG3119	arylsulfatase activity
NXV61_RS24355	COG0668	transmembrane transport
NXV61_RS24360	COG3119	arylsulfatase activity
NXV61_RS24375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXV61_RS24395	COG1629	transport
NXV61_RS24395	COG4206	TonB-dependent receptor
NXV61_RS24405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXV61_RS24415	COG3292	Two component regulator propeller
NXV61_RS24415	COG2205	protein histidine kinase activity
NXV61_RS24415	COG0745	RESPONSE REGULATOR receiver
NXV61_RS24415	COG2205	protein histidine kinase activity
NXV61_RS24415	COG0745	RESPONSE REGULATOR receiver
NXV61_RS24415	COG3292	Two component regulator propeller
NXV61_RS24420	COG3119	arylsulfatase activity
NXV61_RS24470	COG3475	LICD family
NXV61_RS24520	COG4750	Nucleotidyl transferase
NXV61_RS24550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXV61_RS24555	COG1830	Aldolase
NXV61_RS24560	COG0588	phosphoglycerate mutase activity
NXV61_RS24570	COG1119	ATPase activity
NXV61_RS24575	COG1523	belongs to the glycosyl hydrolase 13 family
NXV61_RS24580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXV61_RS24595	COG0560	Phosphoserine phosphatase
NXV61_RS24610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXV61_RS24615	COG2814	Major facilitator Superfamily
NXV61_RS24620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXV61_RS24625	COG0126	phosphoglycerate kinase activity
NXV61_RS24665	COG0778	Nitroreductase
NXV61_RS24675	COG0288	reversible hydration of carbon dioxide
NXV61_RS24685	COG4771	TonB-dependent receptor
NXV61_RS24700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV61_RS24710	COG0511	ligase activity, forming carbon-carbon bonds
NXV61_RS24715	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXV61_RS24725	COG0191	fructose-bisphosphate aldolase activity
NXV61_RS24730	COG0254	rRNA binding
NXV61_RS24735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXV61_RS24740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXV61_RS24830	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS24840	COG1216	Glycosyl transferase, family 2
NXV61_RS24840	COG0463	Glycosyl transferase, family 2
NXV61_RS24855	COG3385	transposase activity
NXV61_RS24865	COG0438	transferase activity, transferring glycosyl groups
NXV61_RS24885	COG2089	acid synthase
NXV61_RS24900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NXV61_RS24910	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXV61_RS24920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXV61_RS24970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXV61_RS24985	COG1280	lysine exporter protein (LysE YggA)
NXV61_RS24995	COG3292	Two component regulator propeller
NXV61_RS24995	COG0745	RESPONSE REGULATOR receiver
NXV61_RS24995	COG0745	RESPONSE REGULATOR receiver
NXV61_RS24995	COG3292	Two component regulator propeller
NXV61_RS24995	COG2205	protein histidine kinase activity
NXV61_RS24995	COG2205	protein histidine kinase activity
NXV61_RS25010	COG1649	PFAM Uncharacterised BCR, COG1649
NXV61_RS25035	COG1966	Carbon starvation protein
NXV61_RS25045	COG1649	PFAM Uncharacterised BCR, COG1649
NXV61_RS25070	COG2113	Glycine betaine
NXV61_RS25075	COG4176	ABC-type proline glycine betaine transport system permease component
NXV61_RS25100	COG2205	protein histidine kinase activity
NXV61_RS25100	COG3292	Two component regulator propeller
NXV61_RS25100	COG0745	RESPONSE REGULATOR receiver
NXV61_RS25110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXV61_RS25110	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NXV61_RS25120	COG1621	beta-fructofuranosidase activity
NXV61_RS25135	COG0561	phosphatase activity
NXV61_RS25140	COG1629	transport
NXV61_RS25140	COG4206	TonB-dependent receptor
NXV61_RS25150	COG1621	beta-fructofuranosidase activity
NXV61_RS25165	COG3250	beta-galactosidase activity
NXV61_RS25170	COG3537	Alpha-1,2-mannosidase
NXV61_RS25195	COG1629	transport
NXV61_RS25205	COG3250	beta-galactosidase activity
NXV61_RS25215	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS25225	COG1472	Belongs to the glycosyl hydrolase 3 family
NXV61_RS25235	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXV61_RS25240	COG0475	glutathione-regulated potassium exporter activity
NXV61_RS25275	COG3279	Response regulator of the LytR AlgR family
NXV61_RS25305	COG2205	protein histidine kinase activity
NXV61_RS25310	COG5002	protein histidine kinase activity
NXV61_RS25325	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXV61_RS25330	COG1960	acyl-CoA dehydrogenase activity
NXV61_RS25350	COG1956	GAF domain-containing protein
NXV61_RS25360	COG0484	heat shock protein binding
NXV61_RS25365	COG2194	sulfuric ester hydrolase activity
NXV61_RS25400	COG0028	Belongs to the TPP enzyme family
NXV61_RS25440	COG0459	protein refolding
NXV61_RS25445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXV61_RS25460	COG5002	protein histidine kinase activity
NXV61_RS25460	COG2205	protein histidine kinase activity
NXV61_RS25460	COG0784	Response regulator, receiver
NXV61_RS25475	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXV61_RS25485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXV61_RS25490	COG0823	Involved in the tonB-independent uptake of proteins
NXV61_RS25490	COG1506	peptidase
NXV61_RS25500	COG0124	histidyl-tRNA synthetase
NXV61_RS25520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXV61_RS25560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXV61_RS25570	COG0671	phosphoesterase, PA-phosphatase related
NXV61_RS25585	COG0473	3-isopropylmalate dehydrogenase activity
NXV61_RS25595	COG0066	3-isopropylmalate dehydratase activity
NXV61_RS25600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXV61_RS25605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXV61_RS25675	COG0463	Glycosyl transferase, family 2
NXV61_RS25695	COG3507	Belongs to the glycosyl hydrolase 43 family
NXV61_RS25700	COG0702	epimerase
NXV61_RS25705	COG4771	TonB-dependent receptor
NXV61_RS25715	COG3328	transposase activity
NXV61_RS25720	COG4206	TonB-dependent receptor
NXV61_RS25720	COG1629	transport
NXV61_RS25740	COG0616	signal peptide processing
NXV61_RS25745	COG1663	tetraacyldisaccharide 4'-kinase activity
NXV61_RS25750	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXV61_RS25755	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXV61_RS25775	COG0513	Belongs to the DEAD box helicase family
NXV61_RS25780	COG2070	2-Nitropropane dioxygenase
NXV61_RS25785	COG0724	RNA recognition motif
NXV61_RS25800	COG3973	AAA domain
NXV61_RS25835	COG1704	LemA family
NXV61_RS25850	COG0534	Mate efflux family protein
NXV61_RS25860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXV61_RS25870	COG1917	Cupin 2, conserved barrel domain protein
NXV61_RS25870	COG4977	sequence-specific DNA binding
NXV61_RS25900	COG1028	Short-chain dehydrogenase reductase Sdr
NXV61_RS25920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXV61_RS25930	COG0439	Biotin carboxylase
NXV61_RS25935	COG0511	ligase activity, forming carbon-carbon bonds
NXV61_RS25935	COG5016	pyruvate
NXV61_RS25940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXV61_RS25950	COG2855	membrane
NXV61_RS25960	COG2873	o-acetylhomoserine
NXV61_RS26000	COG1538	Outer membrane efflux protein
NXV61_RS26030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXV61_RS26045	COG0024	Methionine aminopeptidase
NXV61_RS26050	COG0617	tRNA 3'-terminal CCA addition
NXV61_RS26070	COG0632	four-way junction helicase activity
NXV61_RS26075	COG0673	inositol 2-dehydrogenase activity
NXV61_RS26090	COG1272	protein, Hemolysin III
NXV61_RS26105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXV61_RS26115	COG1328	CTP reductase activity
NXV61_RS26115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXV61_RS26125	COG2814	Major facilitator Superfamily
NXV61_RS26135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXV61_RS26150	COG0750	zinc metalloprotease
NXV61_RS26155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXV61_RS26165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXV61_RS26170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXV61_RS26190	COG0194	GDP metabolic process
NXV61_RS26200	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXV61_RS26205	COG1408	metallophosphoesterase
NXV61_RS26210	COG1575	Belongs to the MenA family. Type 1 subfamily
NXV61_RS26215	COG1088	dTDP-glucose 4,6-dehydratase activity
NXV61_RS26220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXV61_RS26240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXV61_RS26260	COG2205	protein histidine kinase activity
NXV61_RS26290	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS26305	COG4771	TonB-dependent receptor
NXV61_RS26320	COG0784	Response regulator, receiver
NXV61_RS26320	COG2205	protein histidine kinase activity
NXV61_RS26325	COG0488	(ABC) transporter
NXV61_RS26365	COG1595	DNA-templated transcription, initiation
NXV61_RS26380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXV61_RS26390	COG1522	sequence-specific DNA binding
NXV61_RS26420	COG0811	peptide transport
NXV61_RS26430	COG0084	hydrolase, TatD family'
NXV61_RS26450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXV61_RS26455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXV61_RS26460	COG0205	6-phosphofructokinase activity
NXV61_RS26485	COG0372	Belongs to the citrate synthase family
NXV61_RS26490	COG0538	isocitrate dehydrogenase activity
NXV61_RS26495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXV61_RS26500	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXV61_RS26505	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXV61_RS26520	COG0028	Belongs to the TPP enzyme family
NXV61_RS26525	COG0129	dihydroxy-acid dehydratase activity
NXV61_RS26530	COG1047	Peptidyl-prolyl cis-trans
NXV61_RS26535	COG3681	Belongs to the UPF0597 family
NXV61_RS26555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXV61_RS26580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV61_RS26580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV61_RS26585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXV61_RS26590	COG0569	domain protein
NXV61_RS26590	COG2985	domain, Protein
NXV61_RS26625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXV61_RS26630	COG1120	ATPase activity
NXV61_RS26665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXV61_RS26670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXV61_RS26675	COG0166	Belongs to the GPI family
NXV61_RS26705	COG2502	aspartate--ammonia ligase
NXV61_RS26710	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXV61_RS26725	COG3876	Protein conserved in bacteria
NXV61_RS26735	COG2315	Protein conserved in bacteria
NXV61_RS26745	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXV61_RS26895	COG4227	nucleotidyltransferase activity
NXV61_RS26995	COG1196	nuclear chromosome segregation
NXV61_RS26995	COG0739	heme binding
NXV61_RS26995	COG0741	lytic transglycosylase activity