locus-tag	class	description
NXY45_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXY45_RS00010	COG0778	Nitroreductase
NXY45_RS00020	COG1640	4-alpha-glucanotransferase
NXY45_RS00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NXY45_RS00055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXY45_RS00060	COG0318	PFAM AMP-dependent synthetase and ligase
NXY45_RS00095	COG0359	binds to the 23S rRNA
NXY45_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXY45_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
NXY45_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXY45_RS00135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXY45_RS00190	COG1131	(ABC) transporter
NXY45_RS00205	COG2431	L-lysine efflux transmembrane transporter activity
NXY45_RS00215	COG1193	negative regulation of DNA recombination
NXY45_RS00250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXY45_RS00265	COG2234	aminopeptidase activity
NXY45_RS00270	COG3250	beta-galactosidase activity
NXY45_RS00290	COG0702	epimerase
NXY45_RS00295	COG1629	transport
NXY45_RS00310	COG3537	Alpha-1,2-mannosidase
NXY45_RS00325	COG4206	TonB-dependent receptor
NXY45_RS00325	COG1629	transport
NXY45_RS00345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXY45_RS00350	COG0802	atpase or kinase
NXY45_RS00375	COG0714	Associated with various cellular activities
NXY45_RS00420	COG3118	belongs to the thioredoxin family
NXY45_RS00430	COG0688	phosphatidylethanolamine metabolic process
NXY45_RS00435	COG1183	phosphatidylcholine synthase activity
NXY45_RS00455	COG0792	nuclease activity
NXY45_RS00480	COG0534	Mate efflux family protein
NXY45_RS00485	COG0528	UMP kinase activity
NXY45_RS00520	COG0233	cytoplasmic translational termination
NXY45_RS00525	COG1162	GTPase activity
NXY45_RS00535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXY45_RS00555	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXY45_RS00555	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXY45_RS00565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXY45_RS00575	COG4771	TonB-dependent receptor
NXY45_RS00600	COG4771	TonB-dependent receptor
NXY45_RS00610	COG2095	MarC family integral membrane protein
NXY45_RS00625	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXY45_RS00635	COG1435	thymidine kinase activity
NXY45_RS00640	COG0628	permease
NXY45_RS00675	COG0534	Mate efflux family protein
NXY45_RS00735	COG1396	sequence-specific DNA binding
NXY45_RS00755	COG1501	Belongs to the glycosyl hydrolase 31 family
NXY45_RS00770	COG3292	Two component regulator propeller
NXY45_RS00770	COG0745	RESPONSE REGULATOR receiver
NXY45_RS00770	COG2205	protein histidine kinase activity
NXY45_RS00785	COG0702	epimerase
NXY45_RS00790	COG1629	transport
NXY45_RS00800	COG4771	TonB-dependent receptor
NXY45_RS00810	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS00825	COG4771	TonB-dependent receptor
NXY45_RS00860	COG0693	protein deglycase activity
NXY45_RS00925	COG0110	maltose O-acetyltransferase activity
NXY45_RS00935	COG1522	sequence-specific DNA binding
NXY45_RS00960	COG0745	RESPONSE REGULATOR receiver
NXY45_RS00960	COG2205	protein histidine kinase activity
NXY45_RS00960	COG3292	Two component regulator propeller
NXY45_RS00970	COG1629	transport
NXY45_RS00995	COG2818	Glycosylase
NXY45_RS01000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NXY45_RS01005	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXY45_RS01015	COG0252	asparaginase activity
NXY45_RS01025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXY45_RS01030	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXY45_RS01040	COG4771	TonB-dependent receptor
NXY45_RS01060	COG0826	peptidase U32
NXY45_RS01065	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXY45_RS01075	COG0436	Aminotransferase
NXY45_RS01080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXY45_RS01100	COG0519	Catalyzes the synthesis of GMP from XMP
NXY45_RS01105	COG5002	protein histidine kinase activity
NXY45_RS01110	COG2205	protein histidine kinase activity
NXY45_RS01120	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXY45_RS01130	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXY45_RS01170	COG3250	beta-galactosidase activity
NXY45_RS01175	COG2204	response regulator
NXY45_RS01180	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXY45_RS01205	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS01210	COG0737	Belongs to the 5'-nucleotidase family
NXY45_RS01215	COG0737	Belongs to the 5'-nucleotidase family
NXY45_RS01255	COG0335	large ribosomal subunit rRNA binding
NXY45_RS01265	COG1940	carbohydrate kinase activity
NXY45_RS01270	COG1136	(ABC) transporter
NXY45_RS01270	COG0577	efflux transmembrane transporter activity
NXY45_RS01275	COG1136	(ABC) transporter
NXY45_RS01275	COG0577	efflux transmembrane transporter activity
NXY45_RS01280	COG1136	(ABC) transporter
NXY45_RS01280	COG0577	efflux transmembrane transporter activity
NXY45_RS01285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS01290	COG1538	Outer membrane efflux protein
NXY45_RS01295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXY45_RS01295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXY45_RS01305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY45_RS01325	COG2996	Protein conserved in bacteria
NXY45_RS01330	COG0039	L-malate dehydrogenase activity
NXY45_RS01340	COG2217	Heavy metal translocating P-type atpase
NXY45_RS01355	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXY45_RS01360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXY45_RS01365	COG0509	glycine decarboxylation via glycine cleavage system
NXY45_RS01380	COG0514	ATP-dependent DNA helicase (RecQ)
NXY45_RS01395	COG0006	proline dipeptidase activity
NXY45_RS01400	COG3250	beta-galactosidase activity
NXY45_RS01405	COG3408	Glycogen debranching enzyme
NXY45_RS01410	COG3458	cephalosporin-C deacetylase activity
NXY45_RS01425	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXY45_RS01440	COG4206	TonB-dependent receptor
NXY45_RS01440	COG1629	transport
NXY45_RS01470	COG1773	rubredoxin
NXY45_RS01475	COG2205	protein histidine kinase activity
NXY45_RS01475	COG2202	Pas domain
NXY45_RS01480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXY45_RS01485	COG1011	Hydrolase
NXY45_RS01490	COG0196	riboflavin kinase activity
NXY45_RS01495	COG1266	CAAX protease self-immunity
NXY45_RS01505	COG3655	Transcriptional regulator
NXY45_RS01510	COG2166	iron-sulfur cluster assembly
NXY45_RS01515	COG2234	aminopeptidase activity
NXY45_RS01520	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXY45_RS01530	COG0280	phosphate acetyltransferase
NXY45_RS01535	COG3426	butyrate kinase activity
NXY45_RS01560	COG4206	TonB-dependent receptor
NXY45_RS01560	COG1629	transport
NXY45_RS01575	COG1185	polyribonucleotide nucleotidyltransferase activity
NXY45_RS01585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXY45_RS01605	COG1595	DNA-templated transcription, initiation
NXY45_RS01610	COG0076	glutamate decarboxylase activity
NXY45_RS01615	COG2066	Belongs to the glutaminase family
NXY45_RS01625	COG0531	amino acid
NXY45_RS01775	COG0667	Aldo Keto reductase
NXY45_RS01780	COG3250	beta-galactosidase activity
NXY45_RS01810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS01820	COG1309	transcriptional regulator
NXY45_RS01825	COG2986	histidine ammonia-lyase
NXY45_RS01835	COG1228	amidohydrolase
NXY45_RS01845	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXY45_RS01855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXY45_RS01870	COG0203	ribosomal protein L17
NXY45_RS01875	COG0202	RNA polymerase activity
NXY45_RS01880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXY45_RS01885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXY45_RS01890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXY45_RS01895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXY45_RS01900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXY45_RS01915	COG0200	Binds to the 23S rRNA
NXY45_RS01920	COG1841	ribosomal large subunit assembly
NXY45_RS01925	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXY45_RS01930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXY45_RS01935	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXY45_RS01940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXY45_RS01945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXY45_RS01950	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXY45_RS01955	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXY45_RS01960	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXY45_RS01965	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXY45_RS01970	COG0255	Belongs to the universal ribosomal protein uL29 family
NXY45_RS01975	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXY45_RS01980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXY45_RS01985	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXY45_RS01990	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXY45_RS01995	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXY45_RS02000	COG0089	rRNA binding
NXY45_RS02005	COG0088	Forms part of the polypeptide exit tunnel
NXY45_RS02010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXY45_RS02015	COG0051	transcription antitermination factor activity, RNA binding
NXY45_RS02020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXY45_RS02025	COG0049	tRNA binding
NXY45_RS02030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXY45_RS02040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXY45_RS02045	COG0085	RNA polymerase activity
NXY45_RS02050	COG0222	ribosome binding
NXY45_RS02055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXY45_RS02060	COG0081	regulation of translation
NXY45_RS02065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXY45_RS02075	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXY45_RS02085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXY45_RS02115	COG4974	Belongs to the 'phage' integrase family
NXY45_RS02120	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXY45_RS02125	COG0006	proline dipeptidase activity
NXY45_RS02130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXY45_RS02140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXY45_RS02150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXY45_RS02160	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXY45_RS02175	COG1595	DNA-templated transcription, initiation
NXY45_RS02190	COG1027	Aspartate ammonia-lyase
NXY45_RS02195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXY45_RS02200	COG0252	asparaginase activity
NXY45_RS02215	COG2096	Adenosyltransferase
NXY45_RS02250	COG2815	serine threonine protein kinase
NXY45_RS02250	COG0515	serine threonine protein kinase
NXY45_RS02265	COG0631	protein serine/threonine phosphatase activity
NXY45_RS02275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY45_RS02310	COG4974	Belongs to the 'phage' integrase family
NXY45_RS02315	COG4804	nuclease activity
NXY45_RS02435	COG4206	TonB-dependent receptor
NXY45_RS02435	COG1629	transport
NXY45_RS02450	COG4974	Belongs to the 'phage' integrase family
NXY45_RS02485	COG0358	DNA primase activity
NXY45_RS02510	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXY45_RS02510	COG0662	Cupin 2, conserved barrel domain protein
NXY45_RS02515	COG0318	PFAM AMP-dependent synthetase and ligase
NXY45_RS02520	COG1396	sequence-specific DNA binding
NXY45_RS02535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXY45_RS02550	COG2059	Chromate
NXY45_RS02555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXY45_RS02560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXY45_RS02590	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXY45_RS02595	COG2205	protein histidine kinase activity
NXY45_RS02595	COG4999	Histidine kinase
NXY45_RS02595	COG3437	response regulator, receiver
NXY45_RS02595	COG3850	Histidine kinase
NXY45_RS02600	COG0793	Belongs to the peptidase S41A family
NXY45_RS02605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY45_RS02625	COG0483	inositol monophosphate 1-phosphatase activity
NXY45_RS02635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY45_RS02640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXY45_RS02645	COG4206	TonB-dependent receptor
NXY45_RS02645	COG1629	transport
NXY45_RS02675	COG3634	alkyl hydroperoxide reductase activity
NXY45_RS02685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY45_RS02690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXY45_RS02695	COG2816	NAD+ diphosphatase activity
NXY45_RS02710	COG4206	TonB-dependent receptor
NXY45_RS02710	COG1629	transport
NXY45_RS02750	COG0745	RESPONSE REGULATOR receiver
NXY45_RS02750	COG2205	protein histidine kinase activity
NXY45_RS02750	COG3292	Two component regulator propeller
NXY45_RS02765	COG0018	arginyl-trna synthetase
NXY45_RS02775	COG0705	Rhomboid family
NXY45_RS02790	COG0339	signal peptide processing
NXY45_RS02795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXY45_RS02805	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXY45_RS02805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXY45_RS02810	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXY45_RS02815	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXY45_RS02820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXY45_RS02840	COG4974	Belongs to the 'phage' integrase family
NXY45_RS02855	COG0606	chelatase, subunit chli
NXY45_RS02875	COG2205	protein histidine kinase activity
NXY45_RS02885	COG3250	beta-galactosidase activity
NXY45_RS02910	COG3634	alkyl hydroperoxide reductase activity
NXY45_RS02915	COG3250	beta-galactosidase activity
NXY45_RS02940	COG0702	epimerase
NXY45_RS02945	COG4771	TonB-dependent receptor
NXY45_RS02955	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS02960	COG3408	Glycogen debranching enzyme
NXY45_RS02960	COG3119	arylsulfatase activity
NXY45_RS02980	COG3119	arylsulfatase activity
NXY45_RS02985	COG2017	converts alpha-aldose to the beta-anomer
NXY45_RS02990	COG0702	epimerase
NXY45_RS02995	COG4206	TonB-dependent receptor
NXY45_RS02995	COG1629	transport
NXY45_RS03045	COG0673	inositol 2-dehydrogenase activity
NXY45_RS03055	COG0673	inositol 2-dehydrogenase activity
NXY45_RS03060	COG0745	RESPONSE REGULATOR receiver
NXY45_RS03060	COG2205	protein histidine kinase activity
NXY45_RS03060	COG3292	Two component regulator propeller
NXY45_RS03130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY45_RS03130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY45_RS03160	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS03190	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NXY45_RS03195	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS03200	COG1216	Glycosyl transferase, family 2
NXY45_RS03225	COG5492	domain, Protein
NXY45_RS03240	COG0702	epimerase
NXY45_RS03245	COG4771	TonB-dependent receptor
NXY45_RS03250	COG3250	beta-galactosidase activity
NXY45_RS03260	COG2205	protein histidine kinase activity
NXY45_RS03260	COG0745	RESPONSE REGULATOR receiver
NXY45_RS03260	COG3292	Two component regulator propeller
NXY45_RS03265	COG2205	protein histidine kinase activity
NXY45_RS03265	COG3292	Two component regulator propeller
NXY45_RS03265	COG2205	protein histidine kinase activity
NXY45_RS03265	COG0745	RESPONSE REGULATOR receiver
NXY45_RS03265	COG0745	RESPONSE REGULATOR receiver
NXY45_RS03265	COG3292	Two component regulator propeller
NXY45_RS03285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXY45_RS03290	COG0545	Peptidyl-prolyl cis-trans isomerase
NXY45_RS03295	COG0545	Peptidyl-prolyl cis-trans isomerase
NXY45_RS03340	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS03355	COG1629	transport
NXY45_RS03360	COG0561	phosphatase activity
NXY45_RS03415	COG4771	TonB-dependent receptor
NXY45_RS03435	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXY45_RS03440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY45_RS03460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXY45_RS03465	COG0793	Belongs to the peptidase S41A family
NXY45_RS03465	COG3409	Peptidoglycan-binding domain 1 protein
NXY45_RS03510	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS03525	COG1629	transport
NXY45_RS03530	COG2205	protein histidine kinase activity
NXY45_RS03530	COG3292	Two component regulator propeller
NXY45_RS03530	COG0745	RESPONSE REGULATOR receiver
NXY45_RS03550	COG4771	TonB-dependent receptor
NXY45_RS03570	COG3119	arylsulfatase activity
NXY45_RS03575	COG3119	arylsulfatase activity
NXY45_RS03580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS03585	COG3119	arylsulfatase activity
NXY45_RS03600	COG1053	succinate dehydrogenase
NXY45_RS03605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXY45_RS03610	COG3119	arylsulfatase activity
NXY45_RS03635	COG4974	Belongs to the 'phage' integrase family
NXY45_RS03670	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXY45_RS03670	COG0551	DNA topoisomerase type I activity
NXY45_RS03690	COG2205	protein histidine kinase activity
NXY45_RS03690	COG2198	Histidine kinase
NXY45_RS03690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY45_RS03690	COG0784	Response regulator, receiver
NXY45_RS03810	COG0358	DNA primase activity
NXY45_RS03875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXY45_RS03910	COG4771	TonB-dependent receptor
NXY45_RS03915	COG0702	epimerase
NXY45_RS03925	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS03940	COG3345	alpha-galactosidase
NXY45_RS03945	COG0758	DNA mediated transformation
NXY45_RS03945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXY45_RS03955	COG0826	peptidase U32
NXY45_RS03965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXY45_RS03980	COG0557	exoribonuclease II activity
NXY45_RS04000	COG4206	TonB-dependent receptor
NXY45_RS04000	COG1629	transport
NXY45_RS04005	COG0561	phosphatase activity
NXY45_RS04015	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS04025	COG1917	Cupin 2, conserved barrel domain protein
NXY45_RS04030	COG1621	beta-fructofuranosidase activity
NXY45_RS04045	COG1501	Belongs to the glycosyl hydrolase 31 family
NXY45_RS04065	COG0702	epimerase
NXY45_RS04070	COG4771	TonB-dependent receptor
NXY45_RS04095	COG3119	arylsulfatase activity
NXY45_RS04095	COG3408	Glycogen debranching enzyme
NXY45_RS04105	COG0745	RESPONSE REGULATOR receiver
NXY45_RS04105	COG2205	protein histidine kinase activity
NXY45_RS04105	COG3292	Two component regulator propeller
NXY45_RS04110	COG3119	arylsulfatase activity
NXY45_RS04120	COG4771	TonB-dependent receptor
NXY45_RS04145	COG3119	arylsulfatase activity
NXY45_RS04155	COG1073	alpha beta
NXY45_RS04160	COG2814	Major facilitator Superfamily
NXY45_RS04165	COG0012	GTP binding
NXY45_RS04170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXY45_RS04175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXY45_RS04190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXY45_RS04195	COG0662	Cupin 2, conserved barrel domain protein
NXY45_RS04195	COG2207	Transcriptional regulator
NXY45_RS04200	COG0697	spore germination
NXY45_RS04210	COG0495	leucyl-tRNA aminoacylation
NXY45_RS04215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY45_RS04220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXY45_RS04225	COG1360	Flagellar Motor Protein
NXY45_RS04230	COG3537	Alpha-1,2-mannosidase
NXY45_RS04250	COG0745	RESPONSE REGULATOR receiver
NXY45_RS04250	COG3292	Two component regulator propeller
NXY45_RS04250	COG0745	RESPONSE REGULATOR receiver
NXY45_RS04250	COG2205	protein histidine kinase activity
NXY45_RS04250	COG3292	Two component regulator propeller
NXY45_RS04250	COG2205	protein histidine kinase activity
NXY45_RS04270	COG4771	TonB-dependent receptor
NXY45_RS04275	COG0702	epimerase
NXY45_RS04285	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS04295	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS04300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXY45_RS04320	COG0731	radical SAM domain protein
NXY45_RS04320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXY45_RS04330	COG3119	arylsulfatase activity
NXY45_RS04355	COG0659	secondary active sulfate transmembrane transporter activity
NXY45_RS04360	COG1592	Rubrerythrin
NXY45_RS04415	COG0427	acetyl-CoA hydrolase
NXY45_RS04425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXY45_RS04450	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS04505	COG2177	Part of the ABC transporter FtsEX involved in
NXY45_RS04515	COG1968	undecaprenyl-diphosphatase activity
NXY45_RS04520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXY45_RS04525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXY45_RS04535	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXY45_RS04550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXY45_RS04590	COG0594	ribonuclease P activity
NXY45_RS04595	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXY45_RS04605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXY45_RS04615	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXY45_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS04660	COG1629	transport
NXY45_RS04660	COG4206	TonB-dependent receptor
NXY45_RS04685	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXY45_RS04700	COG1121	(ABC) transporter
NXY45_RS04710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY45_RS04710	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NXY45_RS04715	COG1238	metal cluster binding
NXY45_RS04730	COG0823	Involved in the tonB-independent uptake of proteins
NXY45_RS04730	COG1506	peptidase
NXY45_RS04735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXY45_RS04735	COG0116	Belongs to the methyltransferase superfamily
NXY45_RS04740	COG1045	serine acetyltransferase
NXY45_RS04745	COG3275	phosphorelay sensor kinase activity
NXY45_RS04750	COG3279	Response regulator of the LytR AlgR family
NXY45_RS04760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY45_RS04760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXY45_RS04765	COG0142	geranyltranstransferase activity
NXY45_RS04780	COG1694	Mazg nucleotide pyrophosphohydrolase
NXY45_RS04785	COG1490	D-aminoacyl-tRNA deacylase activity
NXY45_RS04790	COG0322	excinuclease ABC activity
NXY45_RS04795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXY45_RS04800	COG0445	tRNA wobble uridine modification
NXY45_RS04815	COG4771	TonB-dependent receptor
NXY45_RS04870	COG2197	response regulator
NXY45_RS04880	COG4206	TonB-dependent receptor
NXY45_RS04880	COG1629	transport
NXY45_RS04900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXY45_RS04905	COG0700	Nucleoside recognition
NXY45_RS04910	COG2255	four-way junction helicase activity
NXY45_RS04930	COG3591	Belongs to the peptidase S1B family
NXY45_RS04935	COG3250	beta-galactosidase activity
NXY45_RS04960	COG0582	viral genome integration into host DNA
NXY45_RS04975	COG0582	viral genome integration into host DNA
NXY45_RS04980	COG3250	beta-galactosidase activity
NXY45_RS04985	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS05005	COG0702	epimerase
NXY45_RS05010	COG4771	TonB-dependent receptor
NXY45_RS05035	COG0513	Belongs to the DEAD box helicase family
NXY45_RS05060	COG0612	Peptidase, M16
NXY45_RS05070	COG4771	TonB-dependent receptor
NXY45_RS05075	COG0702	epimerase
NXY45_RS05090	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS05100	COG0681	Belongs to the peptidase S26 family
NXY45_RS05110	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXY45_RS05120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY45_RS05145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXY45_RS05170	COG4771	TonB-dependent receptor
NXY45_RS05175	COG3119	arylsulfatase activity
NXY45_RS05180	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05180	COG2205	protein histidine kinase activity
NXY45_RS05180	COG3292	Two component regulator propeller
NXY45_RS05180	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05180	COG2205	protein histidine kinase activity
NXY45_RS05180	COG3292	Two component regulator propeller
NXY45_RS05190	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXY45_RS05195	COG1538	Outer membrane efflux protein
NXY45_RS05205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS05210	COG3250	beta-galactosidase activity
NXY45_RS05240	COG4771	TonB-dependent receptor
NXY45_RS05250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY45_RS05255	COG3119	arylsulfatase activity
NXY45_RS05260	COG5492	domain, Protein
NXY45_RS05265	COG0215	cysteine-tRNA ligase activity
NXY45_RS05270	COG0561	phosphatase activity
NXY45_RS05275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXY45_RS05280	COG0482	sulfurtransferase activity
NXY45_RS05290	COG0205	6-phosphofructokinase activity
NXY45_RS05295	COG0571	ribonuclease III activity
NXY45_RS05300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXY45_RS05305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXY45_RS05315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXY45_RS05345	COG1442	glycosyl transferase family 8
NXY45_RS05345	COG1216	Glycosyl transferase, family 2
NXY45_RS05365	COG1215	transferase activity, transferring glycosyl groups
NXY45_RS05370	COG1216	Glycosyl transferase, family 2
NXY45_RS05385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXY45_RS05390	COG0436	Aminotransferase
NXY45_RS05410	COG0463	Glycosyl transferase, family 2
NXY45_RS05440	COG1132	(ABC) transporter
NXY45_RS05465	COG0328	RNA-DNA hybrid ribonuclease activity
NXY45_RS05465	COG3341	Caulimovirus viroplasmin
NXY45_RS05475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXY45_RS05480	COG1166	arginine decarboxylase activity
NXY45_RS05485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NXY45_RS05490	COG1595	DNA-templated transcription, initiation
NXY45_RS05520	COG0779	Required for maturation of 30S ribosomal subunits
NXY45_RS05525	COG0195	Participates in both transcription termination and antitermination
NXY45_RS05530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXY45_RS05540	COG0719	Fe-S assembly protein
NXY45_RS05545	COG0396	ATPase activity
NXY45_RS05550	COG0719	Fe-S assembly protein
NXY45_RS05555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXY45_RS05560	COG0393	Putative heavy-metal-binding
NXY45_RS05580	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05580	COG2205	protein histidine kinase activity
NXY45_RS05580	COG3292	Two component regulator propeller
NXY45_RS05580	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05580	COG2205	protein histidine kinase activity
NXY45_RS05580	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05580	COG3292	Two component regulator propeller
NXY45_RS05580	COG2205	protein histidine kinase activity
NXY45_RS05580	COG3292	Two component regulator propeller
NXY45_RS05585	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXY45_RS05590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXY45_RS05610	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXY45_RS05625	COG0187	DNA topoisomerase II activity
NXY45_RS05630	COG0268	Binds directly to 16S ribosomal RNA
NXY45_RS05645	COG1381	Involved in DNA repair and RecF pathway recombination
NXY45_RS05705	COG1610	YqeY-like protein
NXY45_RS05710	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXY45_RS05725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXY45_RS05730	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXY45_RS05735	COG0772	Belongs to the SEDS family
NXY45_RS05740	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXY45_RS05745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXY45_RS05750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXY45_RS05765	COG0275	rRNA processing
NXY45_RS05770	COG2001	Belongs to the MraZ family
NXY45_RS05775	COG1595	DNA-templated transcription, initiation
NXY45_RS05790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXY45_RS05795	COG0756	dUTP diphosphatase activity
NXY45_RS05810	COG4942	peptidase
NXY45_RS05815	COG3292	Two component regulator propeller
NXY45_RS05815	COG0745	RESPONSE REGULATOR receiver
NXY45_RS05815	COG2205	protein histidine kinase activity
NXY45_RS05835	COG4771	TonB-dependent receptor
NXY45_RS05865	COG3119	arylsulfatase activity
NXY45_RS05880	COG1629	transport
NXY45_RS05915	COG4771	TonB-dependent receptor
NXY45_RS05920	COG0702	epimerase
NXY45_RS05955	COG3250	beta-galactosidase activity
NXY45_RS05975	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS05990	COG1629	transport
NXY45_RS05995	COG0561	phosphatase activity
NXY45_RS06030	COG3537	Alpha-1,2-mannosidase
NXY45_RS06045	COG3537	Alpha-1,2-mannosidase
NXY45_RS06055	COG2017	converts alpha-aldose to the beta-anomer
NXY45_RS06150	COG1373	ATPase (AAA superfamily
NXY45_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXY45_RS06160	COG1022	Amp-dependent synthetase and ligase
NXY45_RS06165	COG0612	Peptidase, M16
NXY45_RS06180	COG2954	triphosphatase activity
NXY45_RS06245	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS06255	COG4771	TonB-dependent receptor
NXY45_RS06310	COG0673	inositol 2-dehydrogenase activity
NXY45_RS06320	COG0673	inositol 2-dehydrogenase activity
NXY45_RS06345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXY45_RS06355	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS06370	COG0561	phosphatase activity
NXY45_RS06375	COG4771	TonB-dependent receptor
NXY45_RS06390	COG2207	Transcriptional regulator
NXY45_RS06390	COG1609	Transcriptional regulator
NXY45_RS06395	COG0423	glycine-tRNA ligase activity
NXY45_RS06405	COG1609	Transcriptional regulator
NXY45_RS06420	COG0738	Major facilitator superfamily
NXY45_RS06425	COG1063	alcohol dehydrogenase
NXY45_RS06440	COG2211	Major facilitator Superfamily
NXY45_RS06445	COG2385	sporulation resulting in formation of a cellular spore
NXY45_RS06445	COG2247	cell wall binding repeat
NXY45_RS06450	COG1215	transferase activity, transferring glycosyl groups
NXY45_RS06455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY45_RS06525	COG0551	DNA topoisomerase type I activity
NXY45_RS06525	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXY45_RS06580	COG0739	heme binding
NXY45_RS06630	COG5002	protein histidine kinase activity
NXY45_RS06630	COG0784	Response regulator, receiver
NXY45_RS06630	COG2198	Histidine kinase
NXY45_RS06635	COG3292	Two component regulator propeller
NXY45_RS06635	COG2205	protein histidine kinase activity
NXY45_RS06635	COG0745	RESPONSE REGULATOR receiver
NXY45_RS06645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS06670	COG2271	Major facilitator Superfamily
NXY45_RS06695	COG4771	TonB-dependent receptor
NXY45_RS06700	COG0702	epimerase
NXY45_RS06710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS06735	COG4771	TonB-dependent receptor
NXY45_RS06750	COG3969	phosphoadenosine phosphosulfate
NXY45_RS06755	COG1475	DNA binding
NXY45_RS06770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXY45_RS06775	COG1970	mechanosensitive ion channel activity
NXY45_RS06780	COG0776	regulation of translation
NXY45_RS06900	COG0702	epimerase
NXY45_RS06905	COG4771	TonB-dependent receptor
NXY45_RS06910	COG0745	RESPONSE REGULATOR receiver
NXY45_RS06910	COG4191	Histidine kinase
NXY45_RS06910	COG2205	protein histidine kinase activity
NXY45_RS06920	COG3119	arylsulfatase activity
NXY45_RS06925	COG5002	protein histidine kinase activity
NXY45_RS06930	COG1629	transport
NXY45_RS06935	COG0702	epimerase
NXY45_RS06965	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS06970	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY45_RS06995	COG0626	cystathionine gamma-synthase activity
NXY45_RS07000	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXY45_RS07005	COG1522	sequence-specific DNA binding
NXY45_RS07010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXY45_RS07010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXY45_RS07015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXY45_RS07020	COG2210	Belongs to the sulfur carrier protein TusA family
NXY45_RS07035	COG4771	TonB-dependent receptor
NXY45_RS07040	COG0702	epimerase
NXY45_RS07065	COG1192	Involved in chromosome partitioning
NXY45_RS07095	COG3344	reverse transcriptase
NXY45_RS07235	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXY45_RS07245	COG0589	response to stress
NXY45_RS07245	COG0475	glutathione-regulated potassium exporter activity
NXY45_RS07250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXY45_RS07255	COG1136	(ABC) transporter
NXY45_RS07265	COG0733	neurotransmitter:sodium symporter activity
NXY45_RS07275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXY45_RS07280	COG0784	Response regulator, receiver
NXY45_RS07280	COG5002	protein histidine kinase activity
NXY45_RS07285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXY45_RS07290	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXY45_RS07295	COG0312	modulator of DNA gyrase
NXY45_RS07300	COG0312	modulator of DNA gyrase
NXY45_RS07305	COG1704	LemA family
NXY45_RS07335	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS07345	COG1501	Belongs to the glycosyl hydrolase 31 family
NXY45_RS07355	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS07380	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS07385	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS07415	COG3292	Two component regulator propeller
NXY45_RS07415	COG2205	protein histidine kinase activity
NXY45_RS07415	COG0745	RESPONSE REGULATOR receiver
NXY45_RS07425	COG4771	TonB-dependent receptor
NXY45_RS07470	COG1346	cytolysis
NXY45_RS07475	COG1380	Effector of murein hydrolase LrgA
NXY45_RS07480	COG0280	phosphate acetyltransferase
NXY45_RS07485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXY45_RS07490	COG1216	Glycosyl transferase, family 2
NXY45_RS07490	COG0463	Glycosyl transferase, family 2
NXY45_RS07495	COG2003	Belongs to the UPF0758 family
NXY45_RS07505	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXY45_RS07510	COG0366	Alpha amylase catalytic
NXY45_RS07525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXY45_RS07530	COG1629	transport
NXY45_RS07530	COG4206	TonB-dependent receptor
NXY45_RS07535	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS07540	COG0366	Alpha amylase catalytic
NXY45_RS07550	COG1785	Belongs to the alkaline phosphatase family
NXY45_RS07555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXY45_RS07560	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXY45_RS07565	COG2815	serine threonine protein kinase
NXY45_RS07565	COG0515	serine threonine protein kinase
NXY45_RS07570	COG0564	pseudouridine synthase activity
NXY45_RS07575	COG1181	Belongs to the D-alanine--D-alanine ligase family
NXY45_RS07595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXY45_RS07600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXY45_RS07605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXY45_RS07610	COG0436	Aminotransferase
NXY45_RS07620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXY45_RS07635	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXY45_RS07640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXY45_RS07650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXY45_RS07650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXY45_RS07655	COG2890	protein-(glutamine-N5) methyltransferase activity
NXY45_RS07665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXY45_RS07675	COG0165	Argininosuccinate lyase
NXY45_RS07690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXY45_RS07710	COG3292	Two component regulator propeller
NXY45_RS07710	COG0745	RESPONSE REGULATOR receiver
NXY45_RS07710	COG2205	protein histidine kinase activity
NXY45_RS07710	COG2205	protein histidine kinase activity
NXY45_RS07710	COG0745	RESPONSE REGULATOR receiver
NXY45_RS07710	COG3292	Two component regulator propeller
NXY45_RS07715	COG0471	metal ion transport
NXY45_RS07770	COG4771	TonB-dependent receptor
NXY45_RS07790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXY45_RS07795	COG1396	sequence-specific DNA binding
NXY45_RS07795	COG1917	Cupin 2, conserved barrel domain protein
NXY45_RS07800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXY45_RS07805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXY45_RS07810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXY45_RS07815	COG0137	argininosuccinate synthase activity
NXY45_RS07825	COG1438	arginine binding
NXY45_RS07830	COG1070	Carbohydrate kinase
NXY45_RS07835	COG4806	L-rhamnose isomerase
NXY45_RS07845	COG0235	Class ii aldolase
NXY45_RS07850	COG1454	alcohol dehydrogenase
NXY45_RS07880	COG0564	pseudouridine synthase activity
NXY45_RS07945	COG3537	Alpha-1,2-mannosidase
NXY45_RS07950	COG3292	Two component regulator propeller
NXY45_RS07950	COG0745	RESPONSE REGULATOR receiver
NXY45_RS07950	COG2205	protein histidine kinase activity
NXY45_RS07960	COG1629	transport
NXY45_RS07960	COG4206	TonB-dependent receptor
NXY45_RS07965	COG0702	epimerase
NXY45_RS08000	COG3119	arylsulfatase activity
NXY45_RS08015	COG3119	arylsulfatase activity
NXY45_RS08020	COG0745	RESPONSE REGULATOR receiver
NXY45_RS08020	COG2205	protein histidine kinase activity
NXY45_RS08020	COG3292	Two component regulator propeller
NXY45_RS08025	COG2204	response regulator
NXY45_RS08030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXY45_RS08035	COG0612	Peptidase, M16
NXY45_RS08040	COG0534	Mate efflux family protein
NXY45_RS08045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY45_RS08045	COG2205	protein histidine kinase activity
NXY45_RS08090	COG0488	(ABC) transporter
NXY45_RS08095	COG3590	peptidase
NXY45_RS08100	COG0138	bifunctional purine biosynthesis protein purh
NXY45_RS08125	COG0772	Belongs to the SEDS family
NXY45_RS08135	COG1774	PSP1 C-terminal conserved region
NXY45_RS08140	COG0470	DNA polymerase III
NXY45_RS08145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXY45_RS08155	COG2193	ferroxidase activity
NXY45_RS08160	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXY45_RS08160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXY45_RS08225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXY45_RS08230	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXY45_RS08235	COG1160	GTP binding
NXY45_RS08245	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXY45_RS08250	COG1127	ABC transporter
NXY45_RS08255	COG0724	RNA recognition motif
NXY45_RS08260	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXY45_RS08265	COG0740	serine-type endopeptidase activity
NXY45_RS08270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXY45_RS08275	COG0514	ATP-dependent DNA helicase (RecQ)
NXY45_RS08280	COG0517	IMP dehydrogenase activity
NXY45_RS08280	COG0516	GMP reductase activity
NXY45_RS08285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXY45_RS08295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXY45_RS08310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXY45_RS08325	COG4771	TonB-dependent receptor
NXY45_RS08345	COG3537	Alpha-1,2-mannosidase
NXY45_RS08380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXY45_RS08390	COG3022	response to hydroperoxide
NXY45_RS08395	COG0110	maltose O-acetyltransferase activity
NXY45_RS08410	COG1187	pseudouridine synthase activity
NXY45_RS08415	COG0017	Asparaginyl-tRNA synthetase
NXY45_RS08425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXY45_RS08430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXY45_RS08435	COG0052	Belongs to the universal ribosomal protein uS2 family
NXY45_RS08440	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXY45_RS08455	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXY45_RS08460	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXY45_RS08465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXY45_RS08480	COG0482	sulfurtransferase activity
NXY45_RS08490	COG1570	exodeoxyribonuclease VII activity
NXY45_RS08500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY45_RS08510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXY45_RS08515	COG0489	protein tyrosine kinase activity
NXY45_RS08520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY45_RS08555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS08575	COG0714	Associated with various cellular activities
NXY45_RS08580	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXY45_RS08585	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NXY45_RS08590	COG0039	L-malate dehydrogenase activity
NXY45_RS08610	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXY45_RS08615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXY45_RS08620	COG0811	peptide transport
NXY45_RS08625	COG0848	biopolymer transport protein
NXY45_RS08640	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXY45_RS08645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXY45_RS08650	COG0105	UTP biosynthetic process
NXY45_RS08655	COG0739	heme binding
NXY45_RS08670	COG0149	triose-phosphate isomerase activity
NXY45_RS08680	COG0302	gtp cyclohydrolase
NXY45_RS08685	COG0358	DNA primase activity
NXY45_RS08695	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXY45_RS08700	COG0436	Aminotransferase
NXY45_RS08715	COG0514	ATP-dependent DNA helicase (RecQ)
NXY45_RS08735	COG0009	L-threonylcarbamoyladenylate synthase
NXY45_RS08745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXY45_RS08750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXY45_RS08755	COG0658	competence protein
NXY45_RS08755	COG2333	competence protein COMEC
NXY45_RS08760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXY45_RS08770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXY45_RS08780	COG4771	TonB-dependent receptor
NXY45_RS08785	COG0561	phosphatase activity
NXY45_RS08805	COG0745	RESPONSE REGULATOR receiver
NXY45_RS08805	COG3292	Two component regulator propeller
NXY45_RS08805	COG2205	protein histidine kinase activity
NXY45_RS08810	COG4771	TonB-dependent receptor
NXY45_RS08830	COG3537	Alpha-1,2-mannosidase
NXY45_RS08835	COG3537	Alpha-1,2-mannosidase
NXY45_RS08845	COG3537	Alpha-1,2-mannosidase
NXY45_RS08850	COG3279	Response regulator of the LytR AlgR family
NXY45_RS08855	COG3275	phosphorelay sensor kinase activity
NXY45_RS08860	COG1566	PFAM secretion protein HlyD family protein
NXY45_RS08870	COG0386	Belongs to the glutathione peroxidase family
NXY45_RS08875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
NXY45_RS08880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXY45_RS08895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXY45_RS08910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXY45_RS08915	COG0742	ribosomal rna small subunit methyltransferase
NXY45_RS08930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXY45_RS08935	COG4771	TonB-dependent receptor
NXY45_RS08970	COG3537	Alpha-1,2-mannosidase
NXY45_RS08975	COG3537	Alpha-1,2-mannosidase
NXY45_RS08995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXY45_RS09000	COG0739	heme binding
NXY45_RS09010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXY45_RS09015	COG0741	lytic transglycosylase activity
NXY45_RS09015	COG1388	LysM domain
NXY45_RS09025	COG1475	DNA binding
NXY45_RS09030	COG1192	Involved in chromosome partitioning
NXY45_RS09035	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXY45_RS09040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXY45_RS09050	COG4589	Belongs to the CDS family
NXY45_RS09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXY45_RS09060	COG0799	negative regulation of ribosome biogenesis
NXY45_RS09070	COG0702	epimerase
NXY45_RS09075	COG1629	transport
NXY45_RS09075	COG4206	TonB-dependent receptor
NXY45_RS09080	COG3291	Pkd domain containing protein
NXY45_RS09080	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS09085	COG1196	nuclear chromosome segregation
NXY45_RS09090	COG2239	Acts as a magnesium transporter
NXY45_RS09095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXY45_RS09105	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXY45_RS09140	COG1119	ATPase activity
NXY45_RS09150	COG0668	transmembrane transport
NXY45_RS09155	COG0662	Cupin 2, conserved barrel domain protein
NXY45_RS09155	COG2207	Transcriptional regulator
NXY45_RS09180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXY45_RS09185	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXY45_RS09190	COG0713	ATP synthesis coupled electron transport
NXY45_RS09205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXY45_RS09210	COG0649	NAD binding
NXY45_RS09210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXY45_RS09215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXY45_RS09220	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXY45_RS09255	COG3250	beta-galactosidase activity
NXY45_RS09265	COG3250	beta-galactosidase activity
NXY45_RS09275	COG0657	acetylesterase activity
NXY45_RS09275	COG2755	lipolytic protein G-D-S-L family
NXY45_RS09295	COG4771	TonB-dependent receptor
NXY45_RS09300	COG0702	epimerase
NXY45_RS09315	COG0702	epimerase
NXY45_RS09330	COG4771	TonB-dependent receptor
NXY45_RS09335	COG0702	epimerase
NXY45_RS09340	COG1629	transport
NXY45_RS09340	COG4206	TonB-dependent receptor
NXY45_RS09355	COG3537	Alpha-1,2-mannosidase
NXY45_RS09375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXY45_RS09380	COG0569	domain protein
NXY45_RS09385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXY45_RS09395	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXY45_RS09400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXY45_RS09405	COG0805	protein transport
NXY45_RS09415	COG2271	Major facilitator Superfamily
NXY45_RS09420	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXY45_RS09425	COG3775	system Galactitol-specific IIC component
NXY45_RS09440	COG2755	lipolytic protein G-D-S-L family
NXY45_RS09445	COG3292	Two component regulator propeller
NXY45_RS09445	COG2205	protein histidine kinase activity
NXY45_RS09445	COG0745	RESPONSE REGULATOR receiver
NXY45_RS09455	COG0702	epimerase
NXY45_RS09460	COG1629	transport
NXY45_RS09480	COG3279	Response regulator of the LytR AlgR family
NXY45_RS09495	COG4206	TonB-dependent receptor
NXY45_RS09495	COG1629	transport
NXY45_RS09510	COG0745	RESPONSE REGULATOR receiver
NXY45_RS09510	COG2205	protein histidine kinase activity
NXY45_RS09510	COG3292	Two component regulator propeller
NXY45_RS09515	COG1242	4 iron, 4 sulfur cluster binding
NXY45_RS09525	COG0363	glucosamine-6-phosphate deaminase activity
NXY45_RS09530	COG0009	L-threonylcarbamoyladenylate synthase
NXY45_RS09540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXY45_RS09545	COG0561	phosphatase activity
NXY45_RS09550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXY45_RS09555	COG1408	metallophosphoesterase
NXY45_RS09580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXY45_RS09605	COG2755	lipolytic protein G-D-S-L family
NXY45_RS09635	COG3401	FG-GAP repeat protein
NXY45_RS09640	COG3250	beta-galactosidase activity
NXY45_RS09650	COG3250	beta-galactosidase activity
NXY45_RS09660	COG3345	alpha-galactosidase
NXY45_RS09675	COG3250	beta-galactosidase activity
NXY45_RS09735	COG4771	TonB-dependent receptor
NXY45_RS09750	COG0702	epimerase
NXY45_RS09755	COG4771	TonB-dependent receptor
NXY45_RS09775	COG4771	TonB-dependent receptor
NXY45_RS09780	COG0702	epimerase
NXY45_RS09795	COG4771	TonB-dependent receptor
NXY45_RS09820	COG2755	lipolytic protein G-D-S-L family
NXY45_RS09830	COG3401	FG-GAP repeat protein
NXY45_RS09840	COG3254	rhamnose metabolic process
NXY45_RS09845	COG3292	Two component regulator propeller
NXY45_RS09845	COG2205	protein histidine kinase activity
NXY45_RS09845	COG0745	RESPONSE REGULATOR receiver
NXY45_RS09845	COG3292	Two component regulator propeller
NXY45_RS09845	COG0745	RESPONSE REGULATOR receiver
NXY45_RS09845	COG2205	protein histidine kinase activity
NXY45_RS09860	COG3250	beta-galactosidase activity
NXY45_RS09865	COG3292	Two component regulator propeller
NXY45_RS09865	COG2205	protein histidine kinase activity
NXY45_RS09865	COG0745	RESPONSE REGULATOR receiver
NXY45_RS09875	COG0546	phosphoglycolate phosphatase activity
NXY45_RS09895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXY45_RS09905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXY45_RS09915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXY45_RS09920	COG0823	Involved in the tonB-independent uptake of proteins
NXY45_RS09920	COG1506	peptidase
NXY45_RS09940	COG5433	transposase activity
NXY45_RS09970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXY45_RS09985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXY45_RS09985	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXY45_RS09990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXY45_RS09995	COG1078	dGTPase activity
NXY45_RS10000	COG0284	orotidine-5'-phosphate decarboxylase activity
NXY45_RS10005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXY45_RS10015	COG1704	LemA family
NXY45_RS10030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXY45_RS10035	COG2226	methyltransferase
NXY45_RS10040	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXY45_RS10045	COG1702	phosphate starvation-inducible protein PhoH
NXY45_RS10060	COG2268	Band 7 protein
NXY45_RS10150	COG2205	protein histidine kinase activity
NXY45_RS10150	COG0745	RESPONSE REGULATOR receiver
NXY45_RS10150	COG3292	Two component regulator propeller
NXY45_RS10155	COG0101	tRNA pseudouridine synthase activity
NXY45_RS10175	COG3250	beta-galactosidase activity
NXY45_RS10180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXY45_RS10185	COG0673	inositol 2-dehydrogenase activity
NXY45_RS10205	COG4771	TonB-dependent receptor
NXY45_RS10225	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY45_RS10230	COG0673	inositol 2-dehydrogenase activity
NXY45_RS10245	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXY45_RS10255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXY45_RS10265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NXY45_RS10270	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXY45_RS10275	COG0793	Belongs to the peptidase S41A family
NXY45_RS10280	COG2131	deaminase
NXY45_RS10290	COG0339	signal peptide processing
NXY45_RS10300	COG1970	mechanosensitive ion channel activity
NXY45_RS10305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXY45_RS10305	COG0519	Catalyzes the synthesis of GMP from XMP
NXY45_RS10315	COG4771	TonB-dependent receptor
NXY45_RS10370	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS10375	COG0463	Glycosyl transferase, family 2
NXY45_RS10450	COG4771	TonB-dependent receptor
NXY45_RS10485	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS10500	COG0297	glycogen (starch) synthase activity
NXY45_RS10505	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXY45_RS10510	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXY45_RS10515	COG0543	2 iron, 2 sulfur cluster binding
NXY45_RS10525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXY45_RS10530	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXY45_RS10535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXY45_RS10550	COG0791	NLP P60 protein
NXY45_RS10565	COG0612	Peptidase, M16
NXY45_RS10570	COG0612	Peptidase, M16
NXY45_RS10575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXY45_RS10580	COG1597	lipid kinase activity
NXY45_RS10585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXY45_RS10600	COG1136	(ABC) transporter
NXY45_RS10620	COG2211	Major facilitator Superfamily
NXY45_RS10625	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXY45_RS10640	COG1674	ftsk spoiiie
NXY45_RS10650	COG0492	ferredoxin-NADP+ reductase activity
NXY45_RS10655	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS10685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXY45_RS10685	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXY45_RS10695	COG1234	tRNA 3'-trailer cleavage
NXY45_RS10715	COG3956	TIGRFAM MazG family protein
NXY45_RS10730	COG0525	valine-tRNA ligase activity
NXY45_RS10735	COG0784	Response regulator, receiver
NXY45_RS10735	COG2205	protein histidine kinase activity
NXY45_RS10750	COG1629	transport
NXY45_RS10750	COG4206	TonB-dependent receptor
NXY45_RS10775	COG0653	protein targeting
NXY45_RS10780	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXY45_RS10790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXY45_RS10810	COG1253	flavin adenine dinucleotide binding
NXY45_RS10820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXY45_RS10830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXY45_RS10835	COG2204	response regulator
NXY45_RS10875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXY45_RS10875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXY45_RS10895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXY45_RS10900	COG0563	adenylate kinase activity
NXY45_RS10905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXY45_RS10910	COG1496	oxidoreductase activity
NXY45_RS10925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS10930	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS10940	COG2814	Major facilitator Superfamily
NXY45_RS10940	COG0477	Major facilitator Superfamily
NXY45_RS10945	COG0457	Tetratricopeptide repeat
NXY45_RS10950	COG2706	6-phosphogluconolactonase activity
NXY45_RS10975	COG1629	transport
NXY45_RS10975	COG4206	TonB-dependent receptor
NXY45_RS11040	COG3142	Participates in the control of copper homeostasis
NXY45_RS11045	COG1418	mRNA catabolic process
NXY45_RS11075	COG1070	Carbohydrate kinase
NXY45_RS11080	COG1063	alcohol dehydrogenase
NXY45_RS11085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXY45_RS11115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXY45_RS11115	COG1333	cytochrome c biogenesis protein
NXY45_RS11155	COG0673	inositol 2-dehydrogenase activity
NXY45_RS11165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXY45_RS11170	COG2832	Protein of unknown function (DUF454)
NXY45_RS11180	COG0602	queuosine metabolic process
NXY45_RS11185	COG0247	lactate metabolic process
NXY45_RS11190	COG1139	Iron-sulfur cluster binding protein
NXY45_RS11200	COG0351	phosphomethylpyrimidine kinase
NXY45_RS11225	COG4589	Belongs to the CDS family
NXY45_RS11235	COG2304	oxidoreductase activity
NXY45_RS11245	COG1393	Belongs to the ArsC family
NXY45_RS11255	COG1629	transport
NXY45_RS11255	COG4206	TonB-dependent receptor
NXY45_RS11270	COG2233	PERMEase
NXY45_RS11275	COG1509	lysine 2,3-aminomutase activity
NXY45_RS11285	COG1115	amino acid carrier protein
NXY45_RS11325	COG1285	pathogenesis
NXY45_RS11335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXY45_RS11340	COG1388	LysM domain
NXY45_RS11340	COG0741	lytic transglycosylase activity
NXY45_RS11370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXY45_RS11385	COG0534	Mate efflux family protein
NXY45_RS11395	COG0564	pseudouridine synthase activity
NXY45_RS11420	COG0346	lactoylglutathione lyase activity
NXY45_RS11440	COG2207	Transcriptional regulator
NXY45_RS11440	COG0662	Cupin 2, conserved barrel domain protein
NXY45_RS11445	COG0653	protein targeting
NXY45_RS11520	COG1205	dead DEAH box helicase
NXY45_RS11520	COG1111	helicase
NXY45_RS11520	COG1111	helicase
NXY45_RS11520	COG1205	dead DEAH box helicase
NXY45_RS11640	COG1910	domain protein
NXY45_RS11665	COG4974	Belongs to the 'phage' integrase family
NXY45_RS11695	COG3326	Membrane
NXY45_RS11755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NXY45_RS11760	COG0629	single-stranded DNA binding
NXY45_RS11850	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY45_RS11915	COG0739	heme binding
NXY45_RS11990	COG3617	BRO family, N-terminal domain
NXY45_RS12070	COG4974	Belongs to the 'phage' integrase family
NXY45_RS12075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NXY45_RS12130	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXY45_RS12145	COG2201	protein-glutamate methylesterase activity
NXY45_RS12150	COG2910	NAD(P)H-binding
NXY45_RS12160	COG4864	UPF0365 protein
NXY45_RS12175	COG0037	tRNA processing
NXY45_RS12185	COG1477	protein flavinylation
NXY45_RS12190	COG1971	Probably functions as a manganese efflux pump
NXY45_RS12205	COG0463	Glycosyl transferase, family 2
NXY45_RS12230	COG1595	DNA-templated transcription, initiation
NXY45_RS12235	COG0148	phosphopyruvate hydratase activity
NXY45_RS12245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXY45_RS12260	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS12265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXY45_RS12270	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXY45_RS12275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXY45_RS12280	COG4651	solute:proton antiporter activity
NXY45_RS12280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXY45_RS12290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXY45_RS12295	COG0193	aminoacyl-tRNA hydrolase activity
NXY45_RS12300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXY45_RS12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXY45_RS12315	COG1862	Preprotein translocase
NXY45_RS12325	COG0237	dephospho-CoA kinase activity
NXY45_RS12340	COG0542	response to heat
NXY45_RS12350	COG0583	DNA-binding transcription factor activity
NXY45_RS12360	COG2855	membrane
NXY45_RS12365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXY45_RS12370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXY45_RS12390	COG0443	Heat shock 70 kDa protein
NXY45_RS12395	COG0306	phosphate transporter
NXY45_RS12405	COG0586	Pfam SNARE associated Golgi protein
NXY45_RS12455	COG0038	chloride channel
NXY45_RS12460	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXY45_RS12485	COG3119	arylsulfatase activity
NXY45_RS12495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY45_RS12500	COG0702	epimerase
NXY45_RS12505	COG4771	TonB-dependent receptor
NXY45_RS12515	COG5434	Belongs to the glycosyl hydrolase 28 family
NXY45_RS12520	COG0745	RESPONSE REGULATOR receiver
NXY45_RS12520	COG2205	protein histidine kinase activity
NXY45_RS12520	COG3292	Two component regulator propeller
NXY45_RS12525	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXY45_RS12530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXY45_RS12540	COG3250	beta-galactosidase activity
NXY45_RS12555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXY45_RS12560	COG4206	TonB-dependent receptor
NXY45_RS12560	COG1629	transport
NXY45_RS12570	COG5002	protein histidine kinase activity
NXY45_RS12595	COG1760	l-serine dehydratase
NXY45_RS12600	COG0598	Magnesium transport protein CorA
NXY45_RS12605	COG1193	negative regulation of DNA recombination
NXY45_RS12615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS12630	COG3250	beta-galactosidase activity
NXY45_RS12645	COG0668	transmembrane transport
NXY45_RS12650	COG1523	belongs to the glycosyl hydrolase 13 family
NXY45_RS12660	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXY45_RS12670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS12680	COG1538	Outer membrane efflux protein
NXY45_RS12690	COG0456	acetyltransferase
NXY45_RS12700	COG3189	MarR family transcriptional regulator
NXY45_RS12705	COG0561	phosphatase activity
NXY45_RS12710	COG1169	isochorismate synthase
NXY45_RS12715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXY45_RS12720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXY45_RS12725	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS12730	COG0318	PFAM AMP-dependent synthetase and ligase
NXY45_RS12745	COG4206	TonB-dependent receptor
NXY45_RS12745	COG1629	transport
NXY45_RS12785	COG0783	Belongs to the Dps family
NXY45_RS12790	COG0583	DNA-binding transcription factor activity
NXY45_RS12800	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXY45_RS12830	COG4771	TonB-dependent receptor
NXY45_RS12835	COG0561	phosphatase activity
NXY45_RS12910	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS12915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXY45_RS12920	COG1882	Formate acetyltransferase
NXY45_RS12935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXY45_RS12980	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS12985	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS12990	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXY45_RS13015	COG2205	protein histidine kinase activity
NXY45_RS13015	COG3292	Two component regulator propeller
NXY45_RS13015	COG0745	RESPONSE REGULATOR receiver
NXY45_RS13015	COG3292	Two component regulator propeller
NXY45_RS13015	COG2205	protein histidine kinase activity
NXY45_RS13015	COG0745	RESPONSE REGULATOR receiver
NXY45_RS13020	COG1595	DNA-templated transcription, initiation
NXY45_RS13025	COG1629	transport
NXY45_RS13025	COG4206	TonB-dependent receptor
NXY45_RS13050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY45_RS13060	COG1253	flavin adenine dinucleotide binding
NXY45_RS13065	COG0501	Belongs to the peptidase M48B family
NXY45_RS13090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY45_RS13095	COG0482	sulfurtransferase activity
NXY45_RS13100	COG2197	response regulator
NXY45_RS13110	COG1757	Na H antiporter
NXY45_RS13125	COG2814	Major facilitator Superfamily
NXY45_RS13130	COG4953	penicillin-binding protein 1C
NXY45_RS13135	COG2373	Large extracellular alpha-helical protein
NXY45_RS13140	COG0545	Peptidyl-prolyl cis-trans isomerase
NXY45_RS13240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXY45_RS13245	COG0646	methionine synthase
NXY45_RS13245	COG1410	methionine synthase
NXY45_RS13250	COG0778	Nitroreductase
NXY45_RS13255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXY45_RS13265	COG0572	uridine kinase
NXY45_RS13275	COG4232	protein-disulfide reductase activity
NXY45_RS13280	COG1741	Belongs to the pirin family
NXY45_RS13295	COG1629	transport
NXY45_RS13300	COG0702	epimerase
NXY45_RS13325	COG2271	Major facilitator Superfamily
NXY45_RS13345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXY45_RS13350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXY45_RS13355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXY45_RS13360	COG0131	Imidazoleglycerol-phosphate dehydratase
NXY45_RS13370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXY45_RS13370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXY45_RS13375	COG4771	TonB-dependent receptor
NXY45_RS13405	COG1404	Belongs to the peptidase S8 family
NXY45_RS13425	COG1592	Rubrerythrin
NXY45_RS13425	COG1773	rubredoxin
NXY45_RS13455	COG3591	Belongs to the peptidase S1B family
NXY45_RS13460	COG3591	Belongs to the peptidase S1B family
NXY45_RS13465	COG0641	radical SAM
NXY45_RS13495	COG0420	3'-5' exonuclease activity
NXY45_RS13505	COG1408	metallophosphoesterase
NXY45_RS13520	COG0646	methionine synthase
NXY45_RS13520	COG1410	methionine synthase
NXY45_RS13530	COG0463	Glycosyl transferase, family 2
NXY45_RS13535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NXY45_RS13545	COG1032	radical SAM domain protein
NXY45_RS13565	COG0363	glucosamine-6-phosphate deaminase activity
NXY45_RS13570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXY45_RS13605	COG0745	RESPONSE REGULATOR receiver
NXY45_RS13605	COG2205	protein histidine kinase activity
NXY45_RS13605	COG3292	Two component regulator propeller
NXY45_RS13610	COG1629	transport
NXY45_RS13620	COG0702	epimerase
NXY45_RS13635	COG4771	TonB-dependent receptor
NXY45_RS13690	COG0811	peptide transport
NXY45_RS13695	COG0848	biopolymer transport protein
NXY45_RS13745	COG1131	(ABC) transporter
NXY45_RS13780	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXY45_RS13820	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXY45_RS13825	COG0022	dehydrogenase e1 component
NXY45_RS13835	COG2264	protein methyltransferase activity
NXY45_RS13855	COG0590	tRNA wobble adenosine to inosine editing
NXY45_RS13860	COG0673	inositol 2-dehydrogenase activity
NXY45_RS13885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXY45_RS13930	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXY45_RS13945	COG1501	Belongs to the glycosyl hydrolase 31 family
NXY45_RS13950	COG5012	cobalamin binding
NXY45_RS13970	COG0698	ribose 5-phosphate isomerase
NXY45_RS13975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NXY45_RS13990	COG1070	Carbohydrate kinase
NXY45_RS13995	COG2160	L-arabinose isomerase activity
NXY45_RS14025	COG0702	epimerase
NXY45_RS14030	COG4206	TonB-dependent receptor
NXY45_RS14030	COG1629	transport
NXY45_RS14035	COG0702	epimerase
NXY45_RS14040	COG1629	transport
NXY45_RS14040	COG4206	TonB-dependent receptor
NXY45_RS14050	COG2205	protein histidine kinase activity
NXY45_RS14050	COG0745	RESPONSE REGULATOR receiver
NXY45_RS14050	COG3292	Two component regulator propeller
NXY45_RS14055	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS14065	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS14070	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXY45_RS14085	COG1482	cell wall glycoprotein biosynthetic process
NXY45_RS14090	COG4974	Belongs to the 'phage' integrase family
NXY45_RS14150	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS14175	COG0297	glycogen (starch) synthase activity
NXY45_RS14175	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS14190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY45_RS14220	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS14260	COG4221	oxidoreductase activity
NXY45_RS14270	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXY45_RS14275	COG3273	potassium ion transport
NXY45_RS14275	COG0471	metal ion transport
NXY45_RS14280	COG0529	Catalyzes the synthesis of activated sulfate
NXY45_RS14285	COG0175	sulfate reduction
NXY45_RS14290	COG2895	sulfate adenylyltransferase (ATP) activity
NXY45_RS14310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXY45_RS14315	COG0242	peptide deformylase activity
NXY45_RS14325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXY45_RS14330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXY45_RS14335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXY45_RS14340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXY45_RS14350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXY45_RS14355	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXY45_RS14360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NXY45_RS14360	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXY45_RS14360	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXY45_RS14360	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXY45_RS14370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXY45_RS14385	COG1940	carbohydrate kinase activity
NXY45_RS14390	COG2081	HI0933 family
NXY45_RS14415	COG1629	transport
NXY45_RS14420	COG0702	epimerase
NXY45_RS14450	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS14470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS14475	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS14485	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS14495	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS14515	COG4771	TonB-dependent receptor
NXY45_RS14590	COG1629	transport
NXY45_RS14615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS14620	COG2755	lipolytic protein G-D-S-L family
NXY45_RS14620	COG0657	acetylesterase activity
NXY45_RS14630	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS14635	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS14640	COG3250	beta-galactosidase activity
NXY45_RS14675	COG1442	glycosyl transferase family 8
NXY45_RS14675	COG1216	Glycosyl transferase, family 2
NXY45_RS14685	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS14700	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS14705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NXY45_RS14710	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS14730	COG1629	transport
NXY45_RS14735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXY45_RS14740	COG0484	heat shock protein binding
NXY45_RS14745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXY45_RS14750	COG0488	(ABC) transporter
NXY45_RS14765	COG2183	response to ionizing radiation
NXY45_RS14770	COG2205	protein histidine kinase activity
NXY45_RS14770	COG2202	Pas domain
NXY45_RS14775	COG0737	Belongs to the 5'-nucleotidase family
NXY45_RS14815	COG0490	domain, Protein
NXY45_RS14815	COG2985	domain, Protein
NXY45_RS14820	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXY45_RS14830	COG0318	PFAM AMP-dependent synthetase and ligase
NXY45_RS14840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY45_RS14845	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXY45_RS14850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NXY45_RS14855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXY45_RS14865	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXY45_RS14875	COG2837	iron assimilation
NXY45_RS14880	COG2135	peptidase activity
NXY45_RS14885	COG3279	Response regulator of the LytR AlgR family
NXY45_RS14895	COG1136	(ABC) transporter
NXY45_RS14895	COG0577	efflux transmembrane transporter activity
NXY45_RS14900	COG1136	(ABC) transporter
NXY45_RS14905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS14930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXY45_RS14940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXY45_RS14965	COG0501	Belongs to the peptidase M48B family
NXY45_RS14970	COG1704	LemA family
NXY45_RS14985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXY45_RS14990	COG2885	chlorophyll binding
NXY45_RS14995	COG0534	Mate efflux family protein
NXY45_RS15000	COG0657	acetylesterase activity
NXY45_RS15000	COG2755	lipolytic protein G-D-S-L family
NXY45_RS15010	COG1162	GTPase activity
NXY45_RS15030	COG0488	(ABC) transporter
NXY45_RS15060	COG1215	transferase activity, transferring glycosyl groups
NXY45_RS15065	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS15070	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS15075	COG1442	glycosyl transferase family 8
NXY45_RS15085	COG2244	polysaccharide biosynthetic process
NXY45_RS15090	COG1216	Glycosyl transferase, family 2
NXY45_RS15090	COG1442	glycosyl transferase family 8
NXY45_RS15135	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS15145	COG1215	transferase activity, transferring glycosyl groups
NXY45_RS15180	COG1805	sodium ion transport
NXY45_RS15185	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXY45_RS15195	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXY45_RS15200	COG2871	sodium ion transport
NXY45_RS15205	COG0513	Belongs to the DEAD box helicase family
NXY45_RS15210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXY45_RS15225	COG1739	Uncharacterized protein family UPF0029
NXY45_RS15240	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXY45_RS15240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXY45_RS15245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY45_RS15250	COG0357	Ribosomal RNA small subunit methyltransferase G
NXY45_RS15295	COG2217	Heavy metal translocating P-type atpase
NXY45_RS15305	COG0321	lipoyl(octanoyl) transferase activity
NXY45_RS15340	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXY45_RS15350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXY45_RS15365	COG1678	Uncharacterized ACR, COG1678
NXY45_RS15385	COG3275	phosphorelay sensor kinase activity
NXY45_RS15415	COG3969	phosphoadenosine phosphosulfate
NXY45_RS15420	COG1475	DNA binding
NXY45_RS15485	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXY45_RS15505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS15530	COG1629	transport
NXY45_RS15530	COG4206	TonB-dependent receptor
NXY45_RS15560	COG4206	TonB-dependent receptor
NXY45_RS15560	COG1629	transport
NXY45_RS15595	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXY45_RS15600	COG3537	Alpha-1,2-mannosidase
NXY45_RS15615	COG1629	transport
NXY45_RS15615	COG4206	TonB-dependent receptor
NXY45_RS15620	COG0702	epimerase
NXY45_RS15645	COG3408	Glycogen debranching enzyme
NXY45_RS15665	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS15670	COG3408	Glycogen debranching enzyme
NXY45_RS15680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXY45_RS15690	COG0167	dihydroorotate dehydrogenase activity
NXY45_RS15695	COG2755	lipolytic protein G-D-S-L family
NXY45_RS15695	COG0657	acetylesterase activity
NXY45_RS15755	COG3250	beta-galactosidase activity
NXY45_RS15765	COG0784	Response regulator, receiver
NXY45_RS15765	COG2205	protein histidine kinase activity
NXY45_RS15775	COG3250	beta-galactosidase activity
NXY45_RS15780	COG0745	RESPONSE REGULATOR receiver
NXY45_RS15785	COG5002	protein histidine kinase activity
NXY45_RS15865	COG1538	Outer membrane efflux protein
NXY45_RS15885	COG3250	beta-galactosidase activity
NXY45_RS15890	COG0745	RESPONSE REGULATOR receiver
NXY45_RS15890	COG2205	protein histidine kinase activity
NXY45_RS15890	COG3292	Two component regulator propeller
NXY45_RS15920	COG2966	Psort location CytoplasmicMembrane, score
NXY45_RS15935	COG0300	oxidoreductase activity
NXY45_RS15945	COG1011	Hydrolase
NXY45_RS15965	COG1595	DNA-templated transcription, initiation
NXY45_RS16010	COG3292	Two component regulator propeller
NXY45_RS16010	COG2205	protein histidine kinase activity
NXY45_RS16010	COG0745	RESPONSE REGULATOR receiver
NXY45_RS16010	COG0745	RESPONSE REGULATOR receiver
NXY45_RS16010	COG2205	protein histidine kinase activity
NXY45_RS16010	COG3292	Two component regulator propeller
NXY45_RS16025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS16040	COG0442	prolyl-tRNA aminoacylation
NXY45_RS16045	COG0745	RESPONSE REGULATOR receiver
NXY45_RS16050	COG2205	protein histidine kinase activity
NXY45_RS16085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXY45_RS16095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXY45_RS16100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXY45_RS16110	COG0552	protein localization to endoplasmic reticulum
NXY45_RS16115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXY45_RS16120	COG0776	regulation of translation
NXY45_RS16125	COG0776	regulation of translation
NXY45_RS16130	COG0714	Associated with various cellular activities
NXY45_RS16145	COG2304	oxidoreductase activity
NXY45_RS16195	COG0326	Molecular chaperone. Has ATPase activity
NXY45_RS16220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXY45_RS16225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXY45_RS16230	COG0336	Belongs to the RNA methyltransferase TrmD family
NXY45_RS16235	COG0167	dihydroorotate dehydrogenase activity
NXY45_RS16240	COG0543	2 iron, 2 sulfur cluster binding
NXY45_RS16255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXY45_RS16285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXY45_RS16305	COG1132	(ABC) transporter
NXY45_RS16335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXY45_RS16340	COG1597	lipid kinase activity
NXY45_RS16345	COG0156	8-amino-7-oxononanoate synthase activity
NXY45_RS16360	COG4771	TonB-dependent receptor
NXY45_RS16380	COG1136	(ABC) transporter
NXY45_RS16380	COG0577	efflux transmembrane transporter activity
NXY45_RS16400	COG1136	(ABC) transporter
NXY45_RS16425	COG3852	Histidine kinase
NXY45_RS16435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXY45_RS16500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXY45_RS16505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXY45_RS16525	COG0560	Phosphoserine phosphatase
NXY45_RS16525	COG3830	Belongs to the UPF0237 family
NXY45_RS16530	COG0513	Belongs to the DEAD box helicase family
NXY45_RS16560	COG0246	Mannitol dehydrogenase
NXY45_RS16570	COG1904	glucuronate isomerase
NXY45_RS16585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXY45_RS16610	COG3015	lipoprotein NlpE involved in copper resistance
NXY45_RS16640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXY45_RS16655	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXY45_RS16665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXY45_RS16675	COG3153	acetyltransferase
NXY45_RS16675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXY45_RS16680	COG0477	Major facilitator Superfamily
NXY45_RS16680	COG2814	Major facilitator Superfamily
NXY45_RS16685	COG2115	Belongs to the xylose isomerase family
NXY45_RS16700	COG0351	phosphomethylpyrimidine kinase
NXY45_RS16705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXY45_RS16710	COG0045	succinate-CoA ligase (ADP-forming) activity
NXY45_RS16715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXY45_RS16735	COG0724	RNA recognition motif
NXY45_RS16760	COG2326	polyphosphate kinase activity
NXY45_RS16770	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXY45_RS16795	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXY45_RS16810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXY45_RS16815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXY45_RS16825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY45_RS16850	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS16870	COG3292	Two component regulator propeller
NXY45_RS16870	COG0745	RESPONSE REGULATOR receiver
NXY45_RS16870	COG2205	protein histidine kinase activity
NXY45_RS16930	COG2244	polysaccharide biosynthetic process
NXY45_RS16955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXY45_RS16975	COG3958	Transketolase
NXY45_RS16980	COG3959	Transketolase, thiamine diphosphate binding domain
NXY45_RS16985	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS16990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXY45_RS17005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NXY45_RS17025	COG0535	radical SAM domain protein
NXY45_RS17060	COG3250	beta-galactosidase activity
NXY45_RS17065	COG3119	arylsulfatase activity
NXY45_RS17075	COG4206	TonB-dependent receptor
NXY45_RS17075	COG1629	transport
NXY45_RS17100	COG2205	protein histidine kinase activity
NXY45_RS17105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXY45_RS17120	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXY45_RS17135	COG0540	Belongs to the ATCase OTCase family
NXY45_RS17140	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXY45_RS17155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXY45_RS17160	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXY45_RS17165	COG2985	domain, Protein
NXY45_RS17205	COG2207	Transcriptional regulator
NXY45_RS17230	COG2431	L-lysine efflux transmembrane transporter activity
NXY45_RS17235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXY45_RS17245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXY45_RS17250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXY45_RS17255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXY45_RS17260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXY45_RS17265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXY45_RS17270	COG0356	it plays a direct role in the translocation of protons across the membrane
NXY45_RS17280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXY45_RS17285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXY45_RS17310	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS17325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXY45_RS17345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXY45_RS17355	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXY45_RS17365	COG0534	Mate efflux family protein
NXY45_RS17375	COG1136	(ABC) transporter
NXY45_RS17410	COG1151	hydroxylamine reductase activity
NXY45_RS17415	COG2233	PERMEase
NXY45_RS17420	COG3263	regulation of cellular component size
NXY45_RS17425	COG0318	PFAM AMP-dependent synthetase and ligase
NXY45_RS17430	COG1082	Xylose isomerase domain protein TIM barrel
NXY45_RS17435	COG0745	RESPONSE REGULATOR receiver
NXY45_RS17440	COG5002	protein histidine kinase activity
NXY45_RS17460	COG3118	belongs to the thioredoxin family
NXY45_RS17465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXY45_RS17510	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXY45_RS17530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS17560	COG0681	Belongs to the peptidase S26 family
NXY45_RS17635	COG5002	protein histidine kinase activity
NXY45_RS17645	COG0352	thiamine-phosphate diphosphorylase activity
NXY45_RS17650	COG2022	thiamine diphosphate biosynthetic process
NXY45_RS17655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXY45_RS17660	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXY45_RS17665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXY45_RS17670	COG0352	thiamine-phosphate diphosphorylase activity
NXY45_RS17685	COG0574	Belongs to the PEP-utilizing enzyme family
NXY45_RS17685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXY45_RS17690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXY45_RS17695	COG0564	pseudouridine synthase activity
NXY45_RS17715	COG0024	Methionine aminopeptidase
NXY45_RS17735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXY45_RS17745	COG0481	GTPase activity
NXY45_RS17760	COG0708	Exodeoxyribonuclease III
NXY45_RS17775	COG0217	transcriptional regulatory protein
NXY45_RS17780	COG0072	phenylalanine-tRNA ligase activity
NXY45_RS17780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXY45_RS17785	COG0305	Participates in initiation and elongation during chromosome replication
NXY45_RS17790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXY45_RS17795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXY45_RS17800	COG4657	Part of a membrane complex involved in electron transport
NXY45_RS17805	COG4660	Part of a membrane complex involved in electron transport
NXY45_RS17810	COG4659	FMN binding
NXY45_RS17815	COG4658	electron transport chain
NXY45_RS17820	COG4656	Part of a membrane complex involved in electron transport
NXY45_RS17855	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS17860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXY45_RS17870	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXY45_RS17875	COG1216	Glycosyl transferase, family 2
NXY45_RS17895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXY45_RS17905	COG1086	Polysaccharide biosynthesis protein
NXY45_RS17915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NXY45_RS17925	COG1086	Polysaccharide biosynthesis protein
NXY45_RS17980	COG0504	CTP synthase activity
NXY45_RS17985	COG0706	membrane insertase activity
NXY45_RS17990	COG0534	Mate efflux family protein
NXY45_RS17995	COG1506	peptidase
NXY45_RS17995	COG0823	Involved in the tonB-independent uptake of proteins
NXY45_RS18015	COG1983	PspC domain protein
NXY45_RS18020	COG1695	Transcriptional regulator
NXY45_RS18030	COG3104	oligopeptide transport
NXY45_RS18035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXY45_RS18045	COG1388	LysM domain
NXY45_RS18045	COG0860	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS18075	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXY45_RS18080	COG0556	nucleotide-excision repair
NXY45_RS18095	COG2949	membrane
NXY45_RS18100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXY45_RS18110	COG0842	Transport permease protein
NXY45_RS18115	COG0842	Transport permease protein
NXY45_RS18120	COG1131	(ABC) transporter
NXY45_RS18135	COG1917	Cupin 2, conserved barrel domain protein
NXY45_RS18135	COG2207	Transcriptional regulator
NXY45_RS18145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXY45_RS18150	COG0505	Belongs to the CarA family
NXY45_RS18160	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXY45_RS18165	COG0067	glutamate synthase
NXY45_RS18165	COG0069	glutamate synthase activity
NXY45_RS18165	COG0070	glutamate synthase
NXY45_RS18175	COG0367	asparagine synthase
NXY45_RS18190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXY45_RS18195	COG0436	Aminotransferase
NXY45_RS18205	COG0347	Belongs to the P(II) protein family
NXY45_RS18210	COG0004	ammonium transporteR
NXY45_RS18225	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXY45_RS18235	COG0490	domain, Protein
NXY45_RS18235	COG0471	metal ion transport
NXY45_RS18245	COG1979	alcohol dehydrogenase
NXY45_RS18255	COG0133	tryptophan synthase activity
NXY45_RS18260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXY45_RS18270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXY45_RS18275	COG0134	indole-3-glycerol-phosphate synthase activity
NXY45_RS18280	COG0135	phosphoribosylanthranilate isomerase activity
NXY45_RS18285	COG0159	tryptophan synthase activity
NXY45_RS18290	COG0252	asparaginase activity
NXY45_RS18300	COG3292	Two component regulator propeller
NXY45_RS18300	COG2205	protein histidine kinase activity
NXY45_RS18300	COG0745	RESPONSE REGULATOR receiver
NXY45_RS18305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXY45_RS18315	COG0110	maltose O-acetyltransferase activity
NXY45_RS18320	COG2197	response regulator
NXY45_RS18330	COG0138	bifunctional purine biosynthesis protein purh
NXY45_RS18340	COG0716	FMN binding
NXY45_RS18365	COG1132	(ABC) transporter
NXY45_RS18380	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS18390	COG4771	TonB-dependent receptor
NXY45_RS18400	COG4771	TonB-dependent receptor
NXY45_RS18410	COG0490	domain, Protein
NXY45_RS18410	COG2985	domain, Protein
NXY45_RS18415	COG1230	cation diffusion facilitator family transporter
NXY45_RS18430	COG4771	TonB-dependent receptor
NXY45_RS18435	COG1429	ligase activity, forming nitrogen-metal bonds
NXY45_RS18470	COG1609	Transcriptional regulator
NXY45_RS18475	COG2721	sulfolactate sulfo-lyase activity
NXY45_RS18550	COG1733	regulation of RNA biosynthetic process
NXY45_RS18560	COG2198	Histidine kinase
NXY45_RS18560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXY45_RS18560	COG0784	Response regulator, receiver
NXY45_RS18560	COG2205	protein histidine kinase activity
NXY45_RS18570	COG3275	phosphorelay sensor kinase activity
NXY45_RS18595	COG0228	four-way junction DNA binding
NXY45_RS18600	COG2188	Transcriptional regulator
NXY45_RS18605	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXY45_RS18615	COG1070	Carbohydrate kinase
NXY45_RS18625	COG0738	Major facilitator superfamily
NXY45_RS18685	COG1177	transmembrane transport
NXY45_RS18690	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXY45_RS18695	COG3842	ATPase activity
NXY45_RS18700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXY45_RS18705	COG0058	SHG alpha-glucan phosphorylase activity
NXY45_RS18715	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXY45_RS18735	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXY45_RS18810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXY45_RS18815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXY45_RS18820	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS18835	COG1295	ribonuclease BN
NXY45_RS18850	COG0704	Plays a role in the regulation of phosphate uptake
NXY45_RS18855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXY45_RS18860	COG0581	inorganic phosphate transmembrane transporter activity
NXY45_RS18865	COG0573	inorganic phosphate transmembrane transporter activity
NXY45_RS18875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXY45_RS18885	COG0586	Pfam SNARE associated Golgi protein
NXY45_RS18895	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXY45_RS18910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXY45_RS18915	COG0167	dihydroorotate dehydrogenase activity
NXY45_RS18920	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXY45_RS18970	COG1442	glycosyl transferase family 8
NXY45_RS18970	COG1216	Glycosyl transferase, family 2
NXY45_RS18980	COG5039	Polysaccharide pyruvyl transferase
NXY45_RS19025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXY45_RS19030	COG0497	DNA recombination
NXY45_RS19045	COG0592	DNA-directed DNA polymerase activity
NXY45_RS19060	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXY45_RS19060	COG0321	lipoyl(octanoyl) transferase activity
NXY45_RS19065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXY45_RS19075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXY45_RS19080	COG0156	8-amino-7-oxononanoate synthase activity
NXY45_RS19095	COG0019	diaminopimelate decarboxylase activity
NXY45_RS19100	COG0527	aspartate kinase activity
NXY45_RS19105	COG2884	Cell division ATP-binding protein ftsE
NXY45_RS19110	COG0140	phosphoribosyl-ATP diphosphatase activity
NXY45_RS19110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXY45_RS19115	COG0107	imidazoleglycerol-phosphate synthase activity
NXY45_RS19120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXY45_RS19125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXY45_RS19130	COG0788	formyltetrahydrofolate deformylase activity
NXY45_RS19145	COG0693	protein deglycase activity
NXY45_RS19150	COG0656	L-ascorbic acid biosynthetic process
NXY45_RS19170	COG0534	Mate efflux family protein
NXY45_RS19175	COG2076	Multidrug Resistance protein
NXY45_RS19190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXY45_RS19190	COG2885	chlorophyll binding
NXY45_RS19215	COG3546	catalase activity
NXY45_RS19245	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXY45_RS19275	COG0823	Involved in the tonB-independent uptake of proteins
NXY45_RS19275	COG1506	peptidase
NXY45_RS19275	COG4946	Tricorn protease homolog
NXY45_RS19280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXY45_RS19285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXY45_RS19290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NXY45_RS19305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXY45_RS19315	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXY45_RS19330	COG4771	TonB-dependent receptor
NXY45_RS19390	COG1312	Catalyzes the dehydration of D-mannonate
NXY45_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS19400	COG1609	Transcriptional regulator
NXY45_RS19415	COG1929	Belongs to the glycerate kinase type-1 family
NXY45_RS19420	COG2223	nitrite transmembrane transporter activity
NXY45_RS19430	COG4771	TonB-dependent receptor
NXY45_RS19440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXY45_RS19440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXY45_RS19455	COG2226	methyltransferase
NXY45_RS19465	COG5002	protein histidine kinase activity
NXY45_RS19465	COG0784	Response regulator, receiver
NXY45_RS19470	COG0511	ligase activity, forming carbon-carbon bonds
NXY45_RS19475	COG0439	Biotin carboxylase
NXY45_RS19480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXY45_RS19495	COG1620	l-lactate permease
NXY45_RS19500	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NXY45_RS19505	COG1690	Belongs to the RtcB family
NXY45_RS19545	COG0110	maltose O-acetyltransferase activity
NXY45_RS19555	COG0577	efflux transmembrane transporter activity
NXY45_RS19560	COG0577	efflux transmembrane transporter activity
NXY45_RS19560	COG1136	(ABC) transporter
NXY45_RS19575	COG2204	response regulator
NXY45_RS19585	COG0628	permease
NXY45_RS19590	COG1215	transferase activity, transferring glycosyl groups
NXY45_RS19600	COG0569	domain protein
NXY45_RS19600	COG0189	ligase activity
NXY45_RS19605	COG1136	(ABC) transporter
NXY45_RS19605	COG0577	efflux transmembrane transporter activity
NXY45_RS19610	COG0436	Aminotransferase
NXY45_RS19625	COG0488	(ABC) transporter
NXY45_RS19640	COG0745	RESPONSE REGULATOR receiver
NXY45_RS19645	COG5002	protein histidine kinase activity
NXY45_RS19690	COG3033	Beta-eliminating lyase
NXY45_RS19715	COG0629	single-stranded DNA binding
NXY45_RS19720	COG1194	a g-specific adenine glycosylase
NXY45_RS19730	COG1530	ribonuclease E activity
NXY45_RS19735	COG2885	chlorophyll binding
NXY45_RS19750	COG2885	chlorophyll binding
NXY45_RS19800	COG0305	Participates in initiation and elongation during chromosome replication
NXY45_RS19815	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS19835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXY45_RS19845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXY45_RS19860	COG4191	Histidine kinase
NXY45_RS19865	COG2204	response regulator
NXY45_RS19875	COG2205	protein histidine kinase activity
NXY45_RS19875	COG5002	protein histidine kinase activity
NXY45_RS19875	COG0784	Response regulator, receiver
NXY45_RS19895	COG1136	(ABC) transporter
NXY45_RS19905	COG1252	NADH dehydrogenase
NXY45_RS19910	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXY45_RS19925	COG3059	membrane
NXY45_RS19930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXY45_RS19935	COG0488	(ABC) transporter
NXY45_RS19960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXY45_RS19970	COG0739	heme binding
NXY45_RS19975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NXY45_RS19980	COG1629	transport
NXY45_RS19980	COG4206	TonB-dependent receptor
NXY45_RS19990	COG0686	Belongs to the AlaDH PNT family
NXY45_RS20035	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXY45_RS20055	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXY45_RS20065	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXY45_RS20095	COG1595	DNA-templated transcription, initiation
NXY45_RS20110	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXY45_RS20115	COG1741	Belongs to the pirin family
NXY45_RS20120	COG0259	pyridoxamine-phosphate oxidase activity
NXY45_RS20180	COG0456	acetyltransferase
NXY45_RS20245	COG0358	DNA primase activity
NXY45_RS20480	COG1918	ferrous iron import across plasma membrane
NXY45_RS20480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXY45_RS20485	COG0037	tRNA processing
NXY45_RS20500	COG3119	arylsulfatase activity
NXY45_RS20510	COG2205	protein histidine kinase activity
NXY45_RS20510	COG2202	Pas domain
NXY45_RS20515	COG0534	Mate efflux family protein
NXY45_RS20520	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXY45_RS20530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXY45_RS20535	COG1858	cytochrome C peroxidase
NXY45_RS20540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXY45_RS20555	COG1983	PspC domain protein
NXY45_RS20560	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXY45_RS20585	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXY45_RS20620	COG3119	arylsulfatase activity
NXY45_RS20625	COG0668	transmembrane transport
NXY45_RS20630	COG3119	arylsulfatase activity
NXY45_RS20640	COG3250	beta-galactosidase activity
NXY45_RS20645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXY45_RS20650	COG3119	arylsulfatase activity
NXY45_RS20660	COG0702	epimerase
NXY45_RS20665	COG4206	TonB-dependent receptor
NXY45_RS20665	COG1629	transport
NXY45_RS20675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXY45_RS20680	COG1660	Displays ATPase and GTPase activities
NXY45_RS20685	COG0745	RESPONSE REGULATOR receiver
NXY45_RS20685	COG2205	protein histidine kinase activity
NXY45_RS20685	COG3292	Two component regulator propeller
NXY45_RS20685	COG0745	RESPONSE REGULATOR receiver
NXY45_RS20685	COG2205	protein histidine kinase activity
NXY45_RS20685	COG3292	Two component regulator propeller
NXY45_RS20690	COG3119	arylsulfatase activity
NXY45_RS20735	COG1091	dTDP-4-dehydrorhamnose reductase activity
NXY45_RS20750	COG0438	transferase activity, transferring glycosyl groups
NXY45_RS20760	COG1216	Glycosyl transferase, family 2
NXY45_RS20770	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXY45_RS20815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXY45_RS20820	COG1830	Aldolase
NXY45_RS20825	COG0588	phosphoglycerate mutase activity
NXY45_RS20830	COG0784	Response regulator, receiver
NXY45_RS20830	COG2205	protein histidine kinase activity
NXY45_RS20835	COG1119	ATPase activity
NXY45_RS20840	COG1523	belongs to the glycosyl hydrolase 13 family
NXY45_RS20845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXY45_RS20860	COG0560	Phosphoserine phosphatase
NXY45_RS20875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXY45_RS20880	COG2814	Major facilitator Superfamily
NXY45_RS20885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXY45_RS20890	COG0126	phosphoglycerate kinase activity
NXY45_RS20910	COG0424	maF-like protein
NXY45_RS20930	COG0778	Nitroreductase
NXY45_RS20940	COG0288	reversible hydration of carbon dioxide
NXY45_RS20950	COG4771	TonB-dependent receptor
NXY45_RS20965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXY45_RS20975	COG0511	ligase activity, forming carbon-carbon bonds
NXY45_RS20980	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXY45_RS20990	COG0191	fructose-bisphosphate aldolase activity
NXY45_RS20995	COG0254	rRNA binding
NXY45_RS21000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXY45_RS21005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXY45_RS21075	COG1216	Glycosyl transferase, family 2
NXY45_RS21095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NXY45_RS21105	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
NXY45_RS21110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NXY45_RS21135	COG4750	Nucleotidyl transferase
NXY45_RS21175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXY45_RS21190	COG1280	lysine exporter protein (LysE YggA)
NXY45_RS21200	COG3292	Two component regulator propeller
NXY45_RS21200	COG0745	RESPONSE REGULATOR receiver
NXY45_RS21200	COG2205	protein histidine kinase activity
NXY45_RS21200	COG3292	Two component regulator propeller
NXY45_RS21200	COG0745	RESPONSE REGULATOR receiver
NXY45_RS21200	COG2205	protein histidine kinase activity
NXY45_RS21215	COG1649	PFAM Uncharacterised BCR, COG1649
NXY45_RS21240	COG1966	Carbon starvation protein
NXY45_RS21250	COG1649	PFAM Uncharacterised BCR, COG1649
NXY45_RS21275	COG2113	Glycine betaine
NXY45_RS21280	COG4176	ABC-type proline glycine betaine transport system permease component
NXY45_RS21300	COG2205	protein histidine kinase activity
NXY45_RS21300	COG0745	RESPONSE REGULATOR receiver
NXY45_RS21300	COG3292	Two component regulator propeller
NXY45_RS21310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXY45_RS21310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NXY45_RS21320	COG1621	beta-fructofuranosidase activity
NXY45_RS21335	COG0561	phosphatase activity
NXY45_RS21340	COG1629	transport
NXY45_RS21340	COG4206	TonB-dependent receptor
NXY45_RS21350	COG1621	beta-fructofuranosidase activity
NXY45_RS21365	COG3250	beta-galactosidase activity
NXY45_RS21370	COG3537	Alpha-1,2-mannosidase
NXY45_RS21395	COG1629	transport
NXY45_RS21405	COG3250	beta-galactosidase activity
NXY45_RS21415	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS21425	COG1472	Belongs to the glycosyl hydrolase 3 family
NXY45_RS21435	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXY45_RS21440	COG0475	glutathione-regulated potassium exporter activity
NXY45_RS21475	COG3279	Response regulator of the LytR AlgR family
NXY45_RS21500	COG2205	protein histidine kinase activity
NXY45_RS21505	COG2205	protein histidine kinase activity
NXY45_RS21510	COG2205	protein histidine kinase activity
NXY45_RS21525	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXY45_RS21535	COG1960	acyl-CoA dehydrogenase activity
NXY45_RS21555	COG1956	GAF domain-containing protein
NXY45_RS21565	COG0484	heat shock protein binding
NXY45_RS21570	COG2194	sulfuric ester hydrolase activity
NXY45_RS21590	COG1191	sigma factor activity
NXY45_RS21605	COG0028	Belongs to the TPP enzyme family
NXY45_RS21625	COG2885	chlorophyll binding
NXY45_RS21645	COG0459	protein refolding
NXY45_RS21650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXY45_RS21665	COG2205	protein histidine kinase activity
NXY45_RS21665	COG0784	Response regulator, receiver
NXY45_RS21665	COG5002	protein histidine kinase activity
NXY45_RS21680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXY45_RS21690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXY45_RS21695	COG1506	peptidase
NXY45_RS21695	COG0823	Involved in the tonB-independent uptake of proteins
NXY45_RS21705	COG0124	histidyl-tRNA synthetase
NXY45_RS21720	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXY45_RS21745	COG0514	ATP-dependent DNA helicase (RecQ)
NXY45_RS21760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXY45_RS21770	COG0671	phosphoesterase, PA-phosphatase related
NXY45_RS21785	COG0473	3-isopropylmalate dehydrogenase activity
NXY45_RS21795	COG0066	3-isopropylmalate dehydratase activity
NXY45_RS21800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXY45_RS21805	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXY45_RS21870	COG0463	Glycosyl transferase, family 2
NXY45_RS21880	COG4948	Mandelate Racemase Muconate Lactonizing
NXY45_RS21890	COG3507	Belongs to the glycosyl hydrolase 43 family
NXY45_RS21895	COG0702	epimerase
NXY45_RS21900	COG4771	TonB-dependent receptor
NXY45_RS21920	COG0616	signal peptide processing
NXY45_RS21925	COG1663	tetraacyldisaccharide 4'-kinase activity
NXY45_RS21930	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXY45_RS21935	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXY45_RS21955	COG0513	Belongs to the DEAD box helicase family
NXY45_RS21960	COG2070	2-Nitropropane dioxygenase
NXY45_RS21965	COG0724	RNA recognition motif
NXY45_RS21980	COG3973	AAA domain
NXY45_RS22000	COG1704	LemA family
NXY45_RS22015	COG0534	Mate efflux family protein
NXY45_RS22025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NXY45_RS22035	COG4977	sequence-specific DNA binding
NXY45_RS22035	COG1917	Cupin 2, conserved barrel domain protein
NXY45_RS22065	COG1028	Short-chain dehydrogenase reductase Sdr
NXY45_RS22075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXY45_RS22085	COG0439	Biotin carboxylase
NXY45_RS22090	COG0511	ligase activity, forming carbon-carbon bonds
NXY45_RS22090	COG5016	pyruvate
NXY45_RS22095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXY45_RS22105	COG2855	membrane
NXY45_RS22115	COG2873	o-acetylhomoserine
NXY45_RS22155	COG1538	Outer membrane efflux protein
NXY45_RS22185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXY45_RS22205	COG0024	Methionine aminopeptidase
NXY45_RS22210	COG0617	tRNA 3'-terminal CCA addition
NXY45_RS22230	COG0632	four-way junction helicase activity
NXY45_RS22235	COG0673	inositol 2-dehydrogenase activity
NXY45_RS22260	COG1272	protein, Hemolysin III
NXY45_RS22275	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXY45_RS22280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXY45_RS22280	COG1328	CTP reductase activity
NXY45_RS22285	COG0602	queuosine metabolic process
NXY45_RS22290	COG2814	Major facilitator Superfamily
NXY45_RS22295	COG0750	zinc metalloprotease
NXY45_RS22300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXY45_RS22310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXY45_RS22315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXY45_RS22335	COG0194	GDP metabolic process
NXY45_RS22340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXY45_RS22345	COG1408	metallophosphoesterase
NXY45_RS22350	COG1575	Belongs to the MenA family. Type 1 subfamily
NXY45_RS22355	COG1088	dTDP-glucose 4,6-dehydratase activity
NXY45_RS22360	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXY45_RS22370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXY45_RS22390	COG2205	protein histidine kinase activity
NXY45_RS22420	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXY45_RS22435	COG4771	TonB-dependent receptor
NXY45_RS22450	COG0784	Response regulator, receiver
NXY45_RS22450	COG2205	protein histidine kinase activity
NXY45_RS22455	COG0488	(ABC) transporter
NXY45_RS22495	COG1595	DNA-templated transcription, initiation
NXY45_RS22510	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXY45_RS22520	COG1522	sequence-specific DNA binding
NXY45_RS22550	COG0811	peptide transport
NXY45_RS22560	COG0084	hydrolase, TatD family'
NXY45_RS22580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXY45_RS22585	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXY45_RS22590	COG0205	6-phosphofructokinase activity
NXY45_RS22615	COG0372	Belongs to the citrate synthase family
NXY45_RS22620	COG0538	isocitrate dehydrogenase activity
NXY45_RS22625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXY45_RS22630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXY45_RS22635	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXY45_RS22650	COG0028	Belongs to the TPP enzyme family
NXY45_RS22655	COG0129	dihydroxy-acid dehydratase activity
NXY45_RS22660	COG1047	Peptidyl-prolyl cis-trans
NXY45_RS22665	COG3681	Belongs to the UPF0597 family
NXY45_RS22685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXY45_RS22730	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXY45_RS22730	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXY45_RS22735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXY45_RS22740	COG0569	domain protein
NXY45_RS22740	COG2985	domain, Protein
NXY45_RS22750	COG1492	cobalamin metabolic process
NXY45_RS22795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXY45_RS22800	COG1120	ATPase activity
NXY45_RS22810	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
NXY45_RS22820	COG0534	Mate efflux family protein
NXY45_RS22830	COG2188	Transcriptional regulator
NXY45_RS22850	COG1629	transport
NXY45_RS22850	COG4206	TonB-dependent receptor
NXY45_RS22910	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXY45_RS22915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXY45_RS22920	COG0166	Belongs to the GPI family
NXY45_RS22950	COG2502	aspartate--ammonia ligase
NXY45_RS22955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXY45_RS22970	COG3876	Protein conserved in bacteria
NXY45_RS22990	COG0860	N-Acetylmuramoyl-L-alanine amidase