locus-tag	class	description
K6V27_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K6V27_RS00010	COG0778	Nitroreductase
K6V27_RS00020	COG1640	4-alpha-glucanotransferase
K6V27_RS00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K6V27_RS00055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K6V27_RS00060	COG0318	PFAM AMP-dependent synthetase and ligase
K6V27_RS00095	COG0359	binds to the 23S rRNA
K6V27_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K6V27_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
K6V27_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K6V27_RS00135	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K6V27_RS00165	COG1131	(ABC) transporter
K6V27_RS00180	COG2431	L-lysine efflux transmembrane transporter activity
K6V27_RS00225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K6V27_RS00240	COG2234	aminopeptidase activity
K6V27_RS00245	COG3250	beta-galactosidase activity
K6V27_RS00265	COG0702	epimerase
K6V27_RS00270	COG1629	transport
K6V27_RS00285	COG3537	Alpha-1,2-mannosidase
K6V27_RS00300	COG4206	TonB-dependent receptor
K6V27_RS00300	COG1629	transport
K6V27_RS00320	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K6V27_RS00325	COG0802	atpase or kinase
K6V27_RS00350	COG0714	Associated with various cellular activities
K6V27_RS00420	COG3118	belongs to the thioredoxin family
K6V27_RS00430	COG0688	phosphatidylethanolamine metabolic process
K6V27_RS00435	COG1183	phosphatidylcholine synthase activity
K6V27_RS00455	COG0792	nuclease activity
K6V27_RS00480	COG0534	Mate efflux family protein
K6V27_RS00485	COG0528	UMP kinase activity
K6V27_RS00520	COG0233	cytoplasmic translational termination
K6V27_RS00525	COG1162	GTPase activity
K6V27_RS00535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6V27_RS00560	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K6V27_RS00560	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K6V27_RS00570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K6V27_RS00580	COG1629	transport
K6V27_RS00580	COG4206	TonB-dependent receptor
K6V27_RS00600	COG1629	transport
K6V27_RS00605	COG4974	Belongs to the 'phage' integrase family
K6V27_RS00610	COG4771	TonB-dependent receptor
K6V27_RS00620	COG2095	MarC family integral membrane protein
K6V27_RS00635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K6V27_RS00645	COG1435	thymidine kinase activity
K6V27_RS00650	COG0628	permease
K6V27_RS00715	COG0693	protein deglycase activity
K6V27_RS00730	COG2433	Pfam Transposase IS66
K6V27_RS00765	COG1396	sequence-specific DNA binding
K6V27_RS00775	COG4771	TonB-dependent receptor
K6V27_RS00785	COG4771	TonB-dependent receptor
K6V27_RS00820	COG0693	protein deglycase activity
K6V27_RS00865	COG0300	oxidoreductase activity
K6V27_RS00875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6V27_RS00880	COG1595	DNA-templated transcription, initiation
K6V27_RS00885	COG0110	maltose O-acetyltransferase activity
K6V27_RS00895	COG1522	sequence-specific DNA binding
K6V27_RS00920	COG3292	Two component regulator propeller
K6V27_RS00920	COG2205	protein histidine kinase activity
K6V27_RS00920	COG0745	RESPONSE REGULATOR receiver
K6V27_RS00930	COG1629	transport
K6V27_RS00955	COG2818	Glycosylase
K6V27_RS00965	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
K6V27_RS00970	COG0460	homoserine dehydrogenase
K6V27_RS00970	COG0527	aspartate kinase activity
K6V27_RS00975	COG0252	asparaginase activity
K6V27_RS00985	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K6V27_RS00990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
K6V27_RS01000	COG4771	TonB-dependent receptor
K6V27_RS01035	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K6V27_RS01045	COG0436	Aminotransferase
K6V27_RS01050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K6V27_RS01070	COG0519	Catalyzes the synthesis of GMP from XMP
K6V27_RS01075	COG5002	protein histidine kinase activity
K6V27_RS01080	COG2205	protein histidine kinase activity
K6V27_RS01090	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K6V27_RS01100	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K6V27_RS01165	COG2204	response regulator
K6V27_RS01170	COG0446	pyridine nucleotide-disulphide oxidoreductase
K6V27_RS01195	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS01200	COG0737	Belongs to the 5'-nucleotidase family
K6V27_RS01205	COG0737	Belongs to the 5'-nucleotidase family
K6V27_RS01225	COG4974	Belongs to the 'phage' integrase family
K6V27_RS01270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6V27_RS01275	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS01285	COG4771	TonB-dependent receptor
K6V27_RS01345	COG1333	cytochrome c biogenesis protein
K6V27_RS01345	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6V27_RS01420	COG0335	large ribosomal subunit rRNA binding
K6V27_RS01435	COG1940	carbohydrate kinase activity
K6V27_RS01440	COG0577	efflux transmembrane transporter activity
K6V27_RS01440	COG1136	(ABC) transporter
K6V27_RS01445	COG0577	efflux transmembrane transporter activity
K6V27_RS01445	COG1136	(ABC) transporter
K6V27_RS01450	COG0577	efflux transmembrane transporter activity
K6V27_RS01450	COG1136	(ABC) transporter
K6V27_RS01455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS01465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6V27_RS01465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K6V27_RS01475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K6V27_RS01495	COG2996	Protein conserved in bacteria
K6V27_RS01550	COG4974	Belongs to the 'phage' integrase family
K6V27_RS01575	COG0039	L-malate dehydrogenase activity
K6V27_RS01585	COG2217	Heavy metal translocating P-type atpase
K6V27_RS01600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K6V27_RS01605	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K6V27_RS01610	COG0509	glycine decarboxylation via glycine cleavage system
K6V27_RS01625	COG0006	proline dipeptidase activity
K6V27_RS01630	COG3250	beta-galactosidase activity
K6V27_RS01635	COG3408	Glycogen debranching enzyme
K6V27_RS01640	COG3458	cephalosporin-C deacetylase activity
K6V27_RS01655	COG1283	sodium-dependent phosphate transmembrane transporter activity
K6V27_RS01670	COG1629	transport
K6V27_RS01670	COG4206	TonB-dependent receptor
K6V27_RS01705	COG1773	rubredoxin
K6V27_RS01715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K6V27_RS01720	COG1011	Hydrolase
K6V27_RS01725	COG0196	riboflavin kinase activity
K6V27_RS01730	COG1266	CAAX protease self-immunity
K6V27_RS01740	COG3655	Transcriptional regulator
K6V27_RS01745	COG2166	iron-sulfur cluster assembly
K6V27_RS01750	COG2234	aminopeptidase activity
K6V27_RS01755	COG1619	proteins homologs of microcin C7 resistance protein MccF
K6V27_RS01765	COG0280	phosphate acetyltransferase
K6V27_RS01770	COG3426	butyrate kinase activity
K6V27_RS01795	COG1629	transport
K6V27_RS01795	COG4206	TonB-dependent receptor
K6V27_RS01810	COG1185	polyribonucleotide nucleotidyltransferase activity
K6V27_RS01820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K6V27_RS01840	COG1595	DNA-templated transcription, initiation
K6V27_RS01845	COG0076	glutamate decarboxylase activity
K6V27_RS01850	COG2066	Belongs to the glutaminase family
K6V27_RS01860	COG0531	amino acid
K6V27_RS02020	COG0667	Aldo Keto reductase
K6V27_RS02025	COG3250	beta-galactosidase activity
K6V27_RS02060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS02070	COG1309	transcriptional regulator
K6V27_RS02075	COG2986	histidine ammonia-lyase
K6V27_RS02085	COG1228	amidohydrolase
K6V27_RS02095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K6V27_RS02105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K6V27_RS02120	COG0203	ribosomal protein L17
K6V27_RS02125	COG0202	RNA polymerase activity
K6V27_RS02130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K6V27_RS02135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K6V27_RS02140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K6V27_RS02145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K6V27_RS02150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K6V27_RS02165	COG0200	Binds to the 23S rRNA
K6V27_RS02170	COG1841	ribosomal large subunit assembly
K6V27_RS02175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K6V27_RS02180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K6V27_RS02185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K6V27_RS02190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K6V27_RS02195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K6V27_RS02200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K6V27_RS02205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K6V27_RS02210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K6V27_RS02215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K6V27_RS02220	COG0255	Belongs to the universal ribosomal protein uL29 family
K6V27_RS02225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K6V27_RS02230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K6V27_RS02235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K6V27_RS02240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K6V27_RS02245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K6V27_RS02250	COG0089	rRNA binding
K6V27_RS02255	COG0088	Forms part of the polypeptide exit tunnel
K6V27_RS02260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K6V27_RS02265	COG0051	transcription antitermination factor activity, RNA binding
K6V27_RS02270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K6V27_RS02275	COG0049	tRNA binding
K6V27_RS02280	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K6V27_RS02290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K6V27_RS02295	COG0085	RNA polymerase activity
K6V27_RS02300	COG0222	ribosome binding
K6V27_RS02305	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K6V27_RS02310	COG0081	regulation of translation
K6V27_RS02315	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K6V27_RS02325	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K6V27_RS02335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K6V27_RS02365	COG4974	Belongs to the 'phage' integrase family
K6V27_RS02370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K6V27_RS02375	COG0006	proline dipeptidase activity
K6V27_RS02380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K6V27_RS02390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6V27_RS02400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K6V27_RS02410	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K6V27_RS02425	COG1595	DNA-templated transcription, initiation
K6V27_RS02440	COG1027	Aspartate ammonia-lyase
K6V27_RS02445	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K6V27_RS02450	COG0252	asparaginase activity
K6V27_RS02465	COG2096	Adenosyltransferase
K6V27_RS02480	COG3328	transposase activity
K6V27_RS02510	COG0515	serine threonine protein kinase
K6V27_RS02510	COG2815	serine threonine protein kinase
K6V27_RS02525	COG0631	protein serine/threonine phosphatase activity
K6V27_RS02535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6V27_RS02575	COG0662	Cupin 2, conserved barrel domain protein
K6V27_RS02575	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
K6V27_RS02580	COG0318	PFAM AMP-dependent synthetase and ligase
K6V27_RS02585	COG1396	sequence-specific DNA binding
K6V27_RS02600	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K6V27_RS02605	COG1217	gtp-binding protein TYPA
K6V27_RS02615	COG2059	Chromate
K6V27_RS02620	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K6V27_RS02625	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K6V27_RS02655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K6V27_RS02660	COG4999	Histidine kinase
K6V27_RS02660	COG3850	Histidine kinase
K6V27_RS02660	COG3437	response regulator, receiver
K6V27_RS02660	COG2205	protein histidine kinase activity
K6V27_RS02665	COG0793	Belongs to the peptidase S41A family
K6V27_RS02670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6V27_RS02710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6V27_RS02715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K6V27_RS02720	COG4771	TonB-dependent receptor
K6V27_RS02725	COG0702	epimerase
K6V27_RS02755	COG3634	alkyl hydroperoxide reductase activity
K6V27_RS02765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6V27_RS02770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6V27_RS02775	COG2816	NAD+ diphosphatase activity
K6V27_RS02790	COG4206	TonB-dependent receptor
K6V27_RS02790	COG1629	transport
K6V27_RS02830	COG0745	RESPONSE REGULATOR receiver
K6V27_RS02830	COG2205	protein histidine kinase activity
K6V27_RS02830	COG3292	Two component regulator propeller
K6V27_RS02830	COG0745	RESPONSE REGULATOR receiver
K6V27_RS02830	COG2205	protein histidine kinase activity
K6V27_RS02830	COG3292	Two component regulator propeller
K6V27_RS02845	COG0018	arginyl-trna synthetase
K6V27_RS02855	COG0705	Rhomboid family
K6V27_RS02870	COG0339	signal peptide processing
K6V27_RS02875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K6V27_RS02885	COG0674	pyruvate-flavodoxin oxidoreductase activity
K6V27_RS02885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K6V27_RS02890	COG1013	pyruvate-flavodoxin oxidoreductase activity
K6V27_RS02895	COG4591	ABC-type transport system involved in lipoprotein release permease component
K6V27_RS02900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K6V27_RS02920	COG4974	Belongs to the 'phage' integrase family
K6V27_RS02935	COG0606	chelatase, subunit chli
K6V27_RS02955	COG2205	protein histidine kinase activity
K6V27_RS02975	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS02995	COG0561	phosphatase activity
K6V27_RS03000	COG4206	TonB-dependent receptor
K6V27_RS03000	COG1629	transport
K6V27_RS03005	COG2205	protein histidine kinase activity
K6V27_RS03005	COG3292	Two component regulator propeller
K6V27_RS03005	COG2205	protein histidine kinase activity
K6V27_RS03005	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03005	COG3292	Two component regulator propeller
K6V27_RS03005	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03025	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS03030	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS03045	COG1215	transferase activity, transferring glycosyl groups
K6V27_RS03050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K6V27_RS03070	COG1442	glycosyl transferase family 8
K6V27_RS03085	COG1442	glycosyl transferase family 8
K6V27_RS03085	COG1216	Glycosyl transferase, family 2
K6V27_RS03120	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K6V27_RS03140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6V27_RS03145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K6V27_RS03170	COG4771	TonB-dependent receptor
K6V27_RS03185	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03185	COG2205	protein histidine kinase activity
K6V27_RS03185	COG3292	Two component regulator propeller
K6V27_RS03225	COG1629	transport
K6V27_RS03260	COG3940	Belongs to the glycosyl hydrolase 43 family
K6V27_RS03265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K6V27_RS03270	COG3119	arylsulfatase activity
K6V27_RS03295	COG0702	epimerase
K6V27_RS03300	COG1629	transport
K6V27_RS03300	COG4206	TonB-dependent receptor
K6V27_RS03310	COG3250	beta-galactosidase activity
K6V27_RS03315	COG3292	Two component regulator propeller
K6V27_RS03315	COG2205	protein histidine kinase activity
K6V27_RS03315	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6V27_RS03370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6V27_RS03390	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS03400	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS03435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K6V27_RS03440	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS03445	COG1216	Glycosyl transferase, family 2
K6V27_RS03450	COG2133	pyrroloquinoline quinone binding
K6V27_RS03450	COG5183	chlorophyll binding
K6V27_RS03470	COG1629	transport
K6V27_RS03470	COG4206	TonB-dependent receptor
K6V27_RS03485	COG1882	Formate acetyltransferase
K6V27_RS03490	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6V27_RS03520	COG5492	domain, Protein
K6V27_RS03535	COG0702	epimerase
K6V27_RS03540	COG4771	TonB-dependent receptor
K6V27_RS03545	COG3250	beta-galactosidase activity
K6V27_RS03555	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03555	COG2205	protein histidine kinase activity
K6V27_RS03555	COG3292	Two component regulator propeller
K6V27_RS03555	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03555	COG3292	Two component regulator propeller
K6V27_RS03555	COG2205	protein histidine kinase activity
K6V27_RS03575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K6V27_RS03580	COG0545	Peptidyl-prolyl cis-trans isomerase
K6V27_RS03585	COG0545	Peptidyl-prolyl cis-trans isomerase
K6V27_RS03630	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS03645	COG1629	transport
K6V27_RS03650	COG0561	phosphatase activity
K6V27_RS03700	COG4771	TonB-dependent receptor
K6V27_RS03720	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
K6V27_RS03725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6V27_RS03750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K6V27_RS03755	COG0793	Belongs to the peptidase S41A family
K6V27_RS03755	COG3409	Peptidoglycan-binding domain 1 protein
K6V27_RS03810	COG1629	transport
K6V27_RS03825	COG0745	RESPONSE REGULATOR receiver
K6V27_RS03825	COG2205	protein histidine kinase activity
K6V27_RS03825	COG3292	Two component regulator propeller
K6V27_RS03835	COG3119	arylsulfatase activity
K6V27_RS03850	COG1053	succinate dehydrogenase
K6V27_RS03855	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K6V27_RS03865	COG3119	arylsulfatase activity
K6V27_RS03900	COG3345	alpha-galactosidase
K6V27_RS03905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K6V27_RS03905	COG0758	DNA mediated transformation
K6V27_RS03915	COG0826	peptidase U32
K6V27_RS03920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6V27_RS03935	COG0557	exoribonuclease II activity
K6V27_RS03955	COG1917	Cupin 2, conserved barrel domain protein
K6V27_RS03960	COG1621	beta-fructofuranosidase activity
K6V27_RS03975	COG1501	Belongs to the glycosyl hydrolase 31 family
K6V27_RS04005	COG0702	epimerase
K6V27_RS04010	COG4771	TonB-dependent receptor
K6V27_RS04035	COG3119	arylsulfatase activity
K6V27_RS04035	COG3408	Glycogen debranching enzyme
K6V27_RS04045	COG3292	Two component regulator propeller
K6V27_RS04045	COG2205	protein histidine kinase activity
K6V27_RS04045	COG0745	RESPONSE REGULATOR receiver
K6V27_RS04065	COG3119	arylsulfatase activity
K6V27_RS04075	COG4771	TonB-dependent receptor
K6V27_RS04100	COG3119	arylsulfatase activity
K6V27_RS04120	COG2814	Major facilitator Superfamily
K6V27_RS04125	COG0012	GTP binding
K6V27_RS04130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K6V27_RS04135	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K6V27_RS04150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K6V27_RS04155	COG2207	Transcriptional regulator
K6V27_RS04155	COG0662	Cupin 2, conserved barrel domain protein
K6V27_RS04160	COG0697	spore germination
K6V27_RS04170	COG0495	leucyl-tRNA aminoacylation
K6V27_RS04175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K6V27_RS04180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K6V27_RS04185	COG1360	Flagellar Motor Protein
K6V27_RS04190	COG3537	Alpha-1,2-mannosidase
K6V27_RS04210	COG3292	Two component regulator propeller
K6V27_RS04210	COG2205	protein histidine kinase activity
K6V27_RS04210	COG3292	Two component regulator propeller
K6V27_RS04210	COG0745	RESPONSE REGULATOR receiver
K6V27_RS04210	COG2205	protein histidine kinase activity
K6V27_RS04210	COG0745	RESPONSE REGULATOR receiver
K6V27_RS04225	COG1629	transport
K6V27_RS04245	COG5434	Belongs to the glycosyl hydrolase 28 family
K6V27_RS04255	COG0584	glycerophosphoryl diester phosphodiesterase
K6V27_RS04260	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS04265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K6V27_RS04285	COG0731	radical SAM domain protein
K6V27_RS04285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K6V27_RS04290	COG3119	arylsulfatase activity
K6V27_RS04310	COG0659	secondary active sulfate transmembrane transporter activity
K6V27_RS04315	COG1592	Rubrerythrin
K6V27_RS04340	COG2027	D-alanyl-D-alanine carboxypeptidase
K6V27_RS04370	COG0427	acetyl-CoA hydrolase
K6V27_RS04380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K6V27_RS04405	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS04460	COG2177	Part of the ABC transporter FtsEX involved in
K6V27_RS04470	COG1968	undecaprenyl-diphosphatase activity
K6V27_RS04475	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K6V27_RS04480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K6V27_RS04490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K6V27_RS04505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K6V27_RS04530	COG1611	Belongs to the LOG family
K6V27_RS04545	COG0594	ribonuclease P activity
K6V27_RS04550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K6V27_RS04560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K6V27_RS04570	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
K6V27_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
K6V27_RS04615	COG1629	transport
K6V27_RS04615	COG4206	TonB-dependent receptor
K6V27_RS04640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K6V27_RS04655	COG1121	(ABC) transporter
K6V27_RS04665	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K6V27_RS04665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6V27_RS04670	COG1238	metal cluster binding
K6V27_RS04685	COG1506	peptidase
K6V27_RS04685	COG0823	Involved in the tonB-independent uptake of proteins
K6V27_RS04690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K6V27_RS04690	COG0116	Belongs to the methyltransferase superfamily
K6V27_RS04695	COG1045	serine acetyltransferase
K6V27_RS04700	COG3275	phosphorelay sensor kinase activity
K6V27_RS04705	COG3279	Response regulator of the LytR AlgR family
K6V27_RS04720	COG0142	geranyltranstransferase activity
K6V27_RS04735	COG1694	Mazg nucleotide pyrophosphohydrolase
K6V27_RS04740	COG1490	D-aminoacyl-tRNA deacylase activity
K6V27_RS04745	COG0322	excinuclease ABC activity
K6V27_RS04750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K6V27_RS04755	COG0445	tRNA wobble uridine modification
K6V27_RS04770	COG4771	TonB-dependent receptor
K6V27_RS04800	COG2197	response regulator
K6V27_RS04810	COG4206	TonB-dependent receptor
K6V27_RS04810	COG1629	transport
K6V27_RS04830	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K6V27_RS04835	COG0700	Nucleoside recognition
K6V27_RS04840	COG2255	four-way junction helicase activity
K6V27_RS04860	COG3591	Belongs to the peptidase S1B family
K6V27_RS04880	COG0745	RESPONSE REGULATOR receiver
K6V27_RS04880	COG3292	Two component regulator propeller
K6V27_RS04880	COG2205	protein histidine kinase activity
K6V27_RS04885	COG3250	beta-galactosidase activity
K6V27_RS04890	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS04915	COG2755	lipolytic protein G-D-S-L family
K6V27_RS04915	COG0657	acetylesterase activity
K6V27_RS04925	COG0702	epimerase
K6V27_RS04930	COG4771	TonB-dependent receptor
K6V27_RS04960	COG0513	Belongs to the DEAD box helicase family
K6V27_RS04985	COG0612	Peptidase, M16
K6V27_RS04995	COG4771	TonB-dependent receptor
K6V27_RS05000	COG0702	epimerase
K6V27_RS05015	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS05035	COG0681	Belongs to the peptidase S26 family
K6V27_RS05045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K6V27_RS05095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K6V27_RS05105	COG5492	domain, Protein
K6V27_RS05115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K6V27_RS05140	COG0702	epimerase
K6V27_RS05145	COG4771	TonB-dependent receptor
K6V27_RS05150	COG3119	arylsulfatase activity
K6V27_RS05155	COG0745	RESPONSE REGULATOR receiver
K6V27_RS05155	COG2205	protein histidine kinase activity
K6V27_RS05155	COG3292	Two component regulator propeller
K6V27_RS05155	COG2205	protein histidine kinase activity
K6V27_RS05155	COG0745	RESPONSE REGULATOR receiver
K6V27_RS05155	COG3292	Two component regulator propeller
K6V27_RS05165	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6V27_RS05170	COG1538	Outer membrane efflux protein
K6V27_RS05180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS05185	COG3250	beta-galactosidase activity
K6V27_RS05210	COG0702	epimerase
K6V27_RS05215	COG4771	TonB-dependent receptor
K6V27_RS05225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K6V27_RS05230	COG3119	arylsulfatase activity
K6V27_RS05235	COG5492	domain, Protein
K6V27_RS05240	COG0215	cysteine-tRNA ligase activity
K6V27_RS05245	COG0561	phosphatase activity
K6V27_RS05250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K6V27_RS05255	COG0482	sulfurtransferase activity
K6V27_RS05265	COG0205	6-phosphofructokinase activity
K6V27_RS05270	COG0571	ribonuclease III activity
K6V27_RS05275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K6V27_RS05280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K6V27_RS05290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K6V27_RS05320	COG1216	Glycosyl transferase, family 2
K6V27_RS05320	COG1442	glycosyl transferase family 8
K6V27_RS05340	COG1442	glycosyl transferase family 8
K6V27_RS05340	COG1216	Glycosyl transferase, family 2
K6V27_RS05345	COG1216	Glycosyl transferase, family 2
K6V27_RS05360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K6V27_RS05365	COG0436	Aminotransferase
K6V27_RS05385	COG0463	Glycosyl transferase, family 2
K6V27_RS05415	COG1132	(ABC) transporter
K6V27_RS05440	COG0328	RNA-DNA hybrid ribonuclease activity
K6V27_RS05440	COG3341	Caulimovirus viroplasmin
K6V27_RS05450	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K6V27_RS05455	COG1166	arginine decarboxylase activity
K6V27_RS05460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K6V27_RS05465	COG1595	DNA-templated transcription, initiation
K6V27_RS05495	COG0779	Required for maturation of 30S ribosomal subunits
K6V27_RS05500	COG0195	Participates in both transcription termination and antitermination
K6V27_RS05505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K6V27_RS05515	COG0719	Fe-S assembly protein
K6V27_RS05520	COG0396	ATPase activity
K6V27_RS05525	COG0719	Fe-S assembly protein
K6V27_RS05530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K6V27_RS05535	COG0393	Putative heavy-metal-binding
K6V27_RS05545	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
K6V27_RS05550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K6V27_RS05565	COG5433	transposase activity
K6V27_RS05575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K6V27_RS05590	COG0187	DNA topoisomerase II activity
K6V27_RS05595	COG0268	Binds directly to 16S ribosomal RNA
K6V27_RS05610	COG1381	Involved in DNA repair and RecF pathway recombination
K6V27_RS05660	COG1610	YqeY-like protein
K6V27_RS05665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K6V27_RS05680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K6V27_RS05685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K6V27_RS05690	COG0772	Belongs to the SEDS family
K6V27_RS05695	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K6V27_RS05700	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K6V27_RS05705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K6V27_RS05720	COG0275	rRNA processing
K6V27_RS05725	COG2001	Belongs to the MraZ family
K6V27_RS05730	COG1595	DNA-templated transcription, initiation
K6V27_RS05745	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K6V27_RS05750	COG0756	dUTP diphosphatase activity
K6V27_RS05765	COG4942	peptidase
K6V27_RS05770	COG3292	Two component regulator propeller
K6V27_RS05770	COG0745	RESPONSE REGULATOR receiver
K6V27_RS05770	COG2205	protein histidine kinase activity
K6V27_RS05790	COG0673	inositol 2-dehydrogenase activity
K6V27_RS05800	COG0673	inositol 2-dehydrogenase activity
K6V27_RS05810	COG0702	epimerase
K6V27_RS05815	COG4771	TonB-dependent receptor
K6V27_RS05860	COG4771	TonB-dependent receptor
K6V27_RS05865	COG0702	epimerase
K6V27_RS05910	COG1629	transport
K6V27_RS05925	COG3119	arylsulfatase activity
K6V27_RS05960	COG4771	TonB-dependent receptor
K6V27_RS05965	COG0702	epimerase
K6V27_RS06000	COG3250	beta-galactosidase activity
K6V27_RS06020	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS06035	COG1629	transport
K6V27_RS06040	COG0561	phosphatase activity
K6V27_RS06075	COG3537	Alpha-1,2-mannosidase
K6V27_RS06090	COG3537	Alpha-1,2-mannosidase
K6V27_RS06100	COG2017	converts alpha-aldose to the beta-anomer
K6V27_RS06160	COG1373	ATPase (AAA superfamily
K6V27_RS06165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K6V27_RS06170	COG1022	Amp-dependent synthetase and ligase
K6V27_RS06175	COG0612	Peptidase, M16
K6V27_RS06190	COG2954	triphosphatase activity
K6V27_RS06250	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS06260	COG4771	TonB-dependent receptor
K6V27_RS06315	COG0673	inositol 2-dehydrogenase activity
K6V27_RS06320	COG0673	inositol 2-dehydrogenase activity
K6V27_RS06345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K6V27_RS06365	COG3345	alpha-galactosidase
K6V27_RS06395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS06410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K6V27_RS06410	COG0517	IMP dehydrogenase activity
K6V27_RS06425	COG4771	TonB-dependent receptor
K6V27_RS06435	COG2814	Major facilitator Superfamily
K6V27_RS06445	COG3458	cephalosporin-C deacetylase activity
K6V27_RS06450	COG2207	Transcriptional regulator
K6V27_RS06450	COG1609	Transcriptional regulator
K6V27_RS06460	COG0423	glycine-tRNA ligase activity
K6V27_RS06470	COG1609	Transcriptional regulator
K6V27_RS06485	COG0738	Major facilitator superfamily
K6V27_RS06490	COG1063	alcohol dehydrogenase
K6V27_RS06505	COG2211	Major facilitator Superfamily
K6V27_RS06510	COG2247	cell wall binding repeat
K6V27_RS06510	COG2385	sporulation resulting in formation of a cellular spore
K6V27_RS06515	COG1215	transferase activity, transferring glycosyl groups
K6V27_RS06520	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6V27_RS06575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K6V27_RS06585	COG0589	response to stress
K6V27_RS06585	COG0475	glutathione-regulated potassium exporter activity
K6V27_RS06590	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K6V27_RS06595	COG1136	(ABC) transporter
K6V27_RS06605	COG0733	neurotransmitter:sodium symporter activity
K6V27_RS06615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K6V27_RS06620	COG5002	protein histidine kinase activity
K6V27_RS06620	COG0784	Response regulator, receiver
K6V27_RS06625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K6V27_RS06630	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
K6V27_RS06635	COG0312	modulator of DNA gyrase
K6V27_RS06640	COG0312	modulator of DNA gyrase
K6V27_RS06645	COG1704	LemA family
K6V27_RS06675	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS06685	COG5433	transposase activity
K6V27_RS06690	COG1501	Belongs to the glycosyl hydrolase 31 family
K6V27_RS06700	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS06710	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS06715	COG1082	Xylose isomerase domain protein TIM barrel
K6V27_RS06740	COG4206	TonB-dependent receptor
K6V27_RS06740	COG1629	transport
K6V27_RS06780	COG3292	Two component regulator propeller
K6V27_RS06780	COG0745	RESPONSE REGULATOR receiver
K6V27_RS06780	COG2205	protein histidine kinase activity
K6V27_RS06790	COG1629	transport
K6V27_RS06835	COG1346	cytolysis
K6V27_RS06840	COG1380	Effector of murein hydrolase LrgA
K6V27_RS06845	COG0280	phosphate acetyltransferase
K6V27_RS06850	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K6V27_RS06855	COG0463	Glycosyl transferase, family 2
K6V27_RS06855	COG1216	Glycosyl transferase, family 2
K6V27_RS06860	COG2003	Belongs to the UPF0758 family
K6V27_RS06870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6V27_RS06875	COG0366	Alpha amylase catalytic
K6V27_RS06890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6V27_RS06895	COG4206	TonB-dependent receptor
K6V27_RS06895	COG1629	transport
K6V27_RS06900	COG1082	Xylose isomerase domain protein TIM barrel
K6V27_RS06905	COG0366	Alpha amylase catalytic
K6V27_RS06925	COG1785	Belongs to the alkaline phosphatase family
K6V27_RS06930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K6V27_RS06935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K6V27_RS06940	COG0515	serine threonine protein kinase
K6V27_RS06940	COG2815	serine threonine protein kinase
K6V27_RS06945	COG0564	pseudouridine synthase activity
K6V27_RS06950	COG1181	Belongs to the D-alanine--D-alanine ligase family
K6V27_RS06970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K6V27_RS06975	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K6V27_RS06980	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K6V27_RS06985	COG0436	Aminotransferase
K6V27_RS06995	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K6V27_RS07010	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K6V27_RS07015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K6V27_RS07025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6V27_RS07025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K6V27_RS07030	COG2890	protein-(glutamine-N5) methyltransferase activity
K6V27_RS07040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K6V27_RS07050	COG0165	Argininosuccinate lyase
K6V27_RS07065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K6V27_RS07085	COG2205	protein histidine kinase activity
K6V27_RS07085	COG0745	RESPONSE REGULATOR receiver
K6V27_RS07085	COG2205	protein histidine kinase activity
K6V27_RS07085	COG3292	Two component regulator propeller
K6V27_RS07085	COG0745	RESPONSE REGULATOR receiver
K6V27_RS07085	COG3292	Two component regulator propeller
K6V27_RS07090	COG0471	metal ion transport
K6V27_RS07155	COG4771	TonB-dependent receptor
K6V27_RS07175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K6V27_RS07180	COG1396	sequence-specific DNA binding
K6V27_RS07180	COG1917	Cupin 2, conserved barrel domain protein
K6V27_RS07185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K6V27_RS07190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K6V27_RS07195	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K6V27_RS07200	COG0137	argininosuccinate synthase activity
K6V27_RS07210	COG1438	arginine binding
K6V27_RS07215	COG1070	Carbohydrate kinase
K6V27_RS07220	COG4806	L-rhamnose isomerase
K6V27_RS07230	COG0235	Class ii aldolase
K6V27_RS07235	COG1454	alcohol dehydrogenase
K6V27_RS07265	COG0564	pseudouridine synthase activity
K6V27_RS07335	COG3537	Alpha-1,2-mannosidase
K6V27_RS07340	COG2205	protein histidine kinase activity
K6V27_RS07340	COG3292	Two component regulator propeller
K6V27_RS07340	COG0745	RESPONSE REGULATOR receiver
K6V27_RS07350	COG4771	TonB-dependent receptor
K6V27_RS07380	COG3119	arylsulfatase activity
K6V27_RS07395	COG3119	arylsulfatase activity
K6V27_RS07400	COG2205	protein histidine kinase activity
K6V27_RS07400	COG0745	RESPONSE REGULATOR receiver
K6V27_RS07400	COG3292	Two component regulator propeller
K6V27_RS07405	COG2204	response regulator
K6V27_RS07410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K6V27_RS07415	COG0612	Peptidase, M16
K6V27_RS07420	COG0534	Mate efflux family protein
K6V27_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6V27_RS07425	COG2205	protein histidine kinase activity
K6V27_RS07450	COG0488	(ABC) transporter
K6V27_RS07455	COG3590	peptidase
K6V27_RS07460	COG0138	bifunctional purine biosynthesis protein purh
K6V27_RS07485	COG0772	Belongs to the SEDS family
K6V27_RS07495	COG1774	PSP1 C-terminal conserved region
K6V27_RS07500	COG0470	DNA polymerase III
K6V27_RS07505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K6V27_RS07515	COG2193	ferroxidase activity
K6V27_RS07595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K6V27_RS07600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K6V27_RS07605	COG1160	GTP binding
K6V27_RS07615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K6V27_RS07620	COG1127	ABC transporter
K6V27_RS07625	COG0724	RNA recognition motif
K6V27_RS07630	COG0544	peptidyl-prolyl cis-trans isomerase activity
K6V27_RS07635	COG0740	serine-type endopeptidase activity
K6V27_RS07640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K6V27_RS07645	COG0514	ATP-dependent DNA helicase (RecQ)
K6V27_RS07650	COG0516	GMP reductase activity
K6V27_RS07650	COG0517	IMP dehydrogenase activity
K6V27_RS07655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6V27_RS07665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K6V27_RS07680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K6V27_RS07695	COG4771	TonB-dependent receptor
K6V27_RS07715	COG3537	Alpha-1,2-mannosidase
K6V27_RS07750	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K6V27_RS07760	COG3022	response to hydroperoxide
K6V27_RS07765	COG0110	maltose O-acetyltransferase activity
K6V27_RS07785	COG1187	pseudouridine synthase activity
K6V27_RS07790	COG0017	Asparaginyl-tRNA synthetase
K6V27_RS07800	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K6V27_RS07805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K6V27_RS07810	COG0052	Belongs to the universal ribosomal protein uS2 family
K6V27_RS07815	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K6V27_RS07830	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
K6V27_RS07835	COG0179	Fumarylacetoacetate (FAA) hydrolase
K6V27_RS07840	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K6V27_RS07855	COG0482	sulfurtransferase activity
K6V27_RS07865	COG1570	exodeoxyribonuclease VII activity
K6V27_RS07875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K6V27_RS07885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K6V27_RS07890	COG0489	protein tyrosine kinase activity
K6V27_RS07900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K6V27_RS07935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS07955	COG0714	Associated with various cellular activities
K6V27_RS07960	COG2425	protein containing a von Willebrand factor type A (vWA) domain
K6V27_RS07965	COG3552	Protein containing von Willebrand factor type A (VWA) domain
K6V27_RS07970	COG0039	L-malate dehydrogenase activity
K6V27_RS08000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K6V27_RS08005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K6V27_RS08010	COG0811	peptide transport
K6V27_RS08015	COG0848	biopolymer transport protein
K6V27_RS08030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K6V27_RS08035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K6V27_RS08040	COG0105	UTP biosynthetic process
K6V27_RS08045	COG0739	heme binding
K6V27_RS08060	COG0149	triose-phosphate isomerase activity
K6V27_RS08070	COG0302	gtp cyclohydrolase
K6V27_RS08075	COG0358	DNA primase activity
K6V27_RS08085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
K6V27_RS08090	COG0436	Aminotransferase
K6V27_RS08105	COG0514	ATP-dependent DNA helicase (RecQ)
K6V27_RS08110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
K6V27_RS08110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K6V27_RS08125	COG0009	L-threonylcarbamoyladenylate synthase
K6V27_RS08135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K6V27_RS08140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K6V27_RS08145	COG2333	competence protein COMEC
K6V27_RS08145	COG0658	competence protein
K6V27_RS08150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
K6V27_RS08160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6V27_RS08170	COG4771	TonB-dependent receptor
K6V27_RS08175	COG0561	phosphatase activity
K6V27_RS08195	COG0745	RESPONSE REGULATOR receiver
K6V27_RS08195	COG2205	protein histidine kinase activity
K6V27_RS08195	COG3292	Two component regulator propeller
K6V27_RS08200	COG4771	TonB-dependent receptor
K6V27_RS08220	COG3537	Alpha-1,2-mannosidase
K6V27_RS08225	COG3537	Alpha-1,2-mannosidase
K6V27_RS08235	COG3537	Alpha-1,2-mannosidase
K6V27_RS08240	COG3279	Response regulator of the LytR AlgR family
K6V27_RS08245	COG3275	phosphorelay sensor kinase activity
K6V27_RS08250	COG1566	PFAM secretion protein HlyD family protein
K6V27_RS08260	COG0386	Belongs to the glutathione peroxidase family
K6V27_RS08265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
K6V27_RS08270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K6V27_RS08285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K6V27_RS08300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K6V27_RS08305	COG0742	ribosomal rna small subunit methyltransferase
K6V27_RS08320	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6V27_RS08325	COG4771	TonB-dependent receptor
K6V27_RS08360	COG3537	Alpha-1,2-mannosidase
K6V27_RS08365	COG3537	Alpha-1,2-mannosidase
K6V27_RS08385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K6V27_RS08390	COG0739	heme binding
K6V27_RS08400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6V27_RS08405	COG1388	LysM domain
K6V27_RS08405	COG0741	lytic transglycosylase activity
K6V27_RS08415	COG1475	DNA binding
K6V27_RS08420	COG1192	Involved in chromosome partitioning
K6V27_RS08425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K6V27_RS08430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6V27_RS08440	COG4589	Belongs to the CDS family
K6V27_RS08445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K6V27_RS08450	COG0799	negative regulation of ribosome biogenesis
K6V27_RS08460	COG0702	epimerase
K6V27_RS08465	COG1629	transport
K6V27_RS08465	COG4206	TonB-dependent receptor
K6V27_RS08470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS08470	COG3291	Pkd domain containing protein
K6V27_RS08475	COG1196	nuclear chromosome segregation
K6V27_RS08480	COG2239	Acts as a magnesium transporter
K6V27_RS08485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K6V27_RS08495	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6V27_RS08530	COG1119	ATPase activity
K6V27_RS08540	COG0668	transmembrane transport
K6V27_RS08545	COG2207	Transcriptional regulator
K6V27_RS08545	COG0662	Cupin 2, conserved barrel domain protein
K6V27_RS08570	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K6V27_RS08575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K6V27_RS08580	COG0713	ATP synthesis coupled electron transport
K6V27_RS08595	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K6V27_RS08600	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K6V27_RS08600	COG0649	NAD binding
K6V27_RS08605	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K6V27_RS08610	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K6V27_RS08645	COG3250	beta-galactosidase activity
K6V27_RS08655	COG3250	beta-galactosidase activity
K6V27_RS08665	COG2755	lipolytic protein G-D-S-L family
K6V27_RS08665	COG0657	acetylesterase activity
K6V27_RS08680	COG1629	transport
K6V27_RS08685	COG0702	epimerase
K6V27_RS08700	COG0702	epimerase
K6V27_RS08715	COG4771	TonB-dependent receptor
K6V27_RS08720	COG0702	epimerase
K6V27_RS08725	COG1629	transport
K6V27_RS08725	COG4206	TonB-dependent receptor
K6V27_RS08740	COG3537	Alpha-1,2-mannosidase
K6V27_RS08760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6V27_RS08765	COG0569	domain protein
K6V27_RS08770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K6V27_RS08780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K6V27_RS08785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K6V27_RS08790	COG0805	protein transport
K6V27_RS08800	COG2271	Major facilitator Superfamily
K6V27_RS08805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
K6V27_RS08810	COG3775	system Galactitol-specific IIC component
K6V27_RS08825	COG2755	lipolytic protein G-D-S-L family
K6V27_RS08830	COG2205	protein histidine kinase activity
K6V27_RS08830	COG0745	RESPONSE REGULATOR receiver
K6V27_RS08830	COG3292	Two component regulator propeller
K6V27_RS08840	COG0702	epimerase
K6V27_RS08845	COG4771	TonB-dependent receptor
K6V27_RS08865	COG3279	Response regulator of the LytR AlgR family
K6V27_RS08880	COG1629	transport
K6V27_RS08880	COG4206	TonB-dependent receptor
K6V27_RS08895	COG2205	protein histidine kinase activity
K6V27_RS08895	COG3292	Two component regulator propeller
K6V27_RS08895	COG0745	RESPONSE REGULATOR receiver
K6V27_RS08900	COG1242	4 iron, 4 sulfur cluster binding
K6V27_RS08910	COG0363	glucosamine-6-phosphate deaminase activity
K6V27_RS08915	COG0009	L-threonylcarbamoyladenylate synthase
K6V27_RS08925	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6V27_RS08930	COG0561	phosphatase activity
K6V27_RS08935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K6V27_RS08940	COG1408	metallophosphoesterase
K6V27_RS08975	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K6V27_RS09000	COG2755	lipolytic protein G-D-S-L family
K6V27_RS09030	COG3401	FG-GAP repeat protein
K6V27_RS09035	COG3250	beta-galactosidase activity
K6V27_RS09045	COG3345	alpha-galactosidase
K6V27_RS09080	COG4771	TonB-dependent receptor
K6V27_RS09085	COG0702	epimerase
K6V27_RS09100	COG4771	TonB-dependent receptor
K6V27_RS09125	COG2755	lipolytic protein G-D-S-L family
K6V27_RS09135	COG3401	FG-GAP repeat protein
K6V27_RS09145	COG3254	rhamnose metabolic process
K6V27_RS09150	COG3292	Two component regulator propeller
K6V27_RS09150	COG2205	protein histidine kinase activity
K6V27_RS09150	COG0745	RESPONSE REGULATOR receiver
K6V27_RS09150	COG3292	Two component regulator propeller
K6V27_RS09150	COG0745	RESPONSE REGULATOR receiver
K6V27_RS09150	COG2205	protein histidine kinase activity
K6V27_RS09165	COG3250	beta-galactosidase activity
K6V27_RS09170	COG0745	RESPONSE REGULATOR receiver
K6V27_RS09170	COG2205	protein histidine kinase activity
K6V27_RS09170	COG3292	Two component regulator propeller
K6V27_RS09180	COG0546	phosphoglycolate phosphatase activity
K6V27_RS09200	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K6V27_RS09210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K6V27_RS09220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K6V27_RS09225	COG1506	peptidase
K6V27_RS09225	COG0823	Involved in the tonB-independent uptake of proteins
K6V27_RS09270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K6V27_RS09285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K6V27_RS09285	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K6V27_RS09290	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K6V27_RS09295	COG1078	dGTPase activity
K6V27_RS09300	COG0284	orotidine-5'-phosphate decarboxylase activity
K6V27_RS09305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K6V27_RS09315	COG1704	LemA family
K6V27_RS09330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K6V27_RS09335	COG2226	methyltransferase
K6V27_RS09340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K6V27_RS09345	COG1702	phosphate starvation-inducible protein PhoH
K6V27_RS09355	COG2268	Band 7 protein
K6V27_RS09445	COG0745	RESPONSE REGULATOR receiver
K6V27_RS09445	COG2205	protein histidine kinase activity
K6V27_RS09445	COG3292	Two component regulator propeller
K6V27_RS09450	COG0101	tRNA pseudouridine synthase activity
K6V27_RS09470	COG3250	beta-galactosidase activity
K6V27_RS09475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K6V27_RS09480	COG0673	inositol 2-dehydrogenase activity
K6V27_RS09500	COG4771	TonB-dependent receptor
K6V27_RS09520	COG5434	Belongs to the glycosyl hydrolase 28 family
K6V27_RS09525	COG0673	inositol 2-dehydrogenase activity
K6V27_RS09540	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K6V27_RS09550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K6V27_RS09560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K6V27_RS09565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K6V27_RS09570	COG0793	Belongs to the peptidase S41A family
K6V27_RS09575	COG2131	deaminase
K6V27_RS09585	COG0339	signal peptide processing
K6V27_RS09595	COG1970	mechanosensitive ion channel activity
K6V27_RS09600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K6V27_RS09600	COG0519	Catalyzes the synthesis of GMP from XMP
K6V27_RS09615	COG4771	TonB-dependent receptor
K6V27_RS09700	COG4771	TonB-dependent receptor
K6V27_RS09730	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS09745	COG0297	glycogen (starch) synthase activity
K6V27_RS09750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K6V27_RS09755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
K6V27_RS09760	COG0543	2 iron, 2 sulfur cluster binding
K6V27_RS09770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K6V27_RS09775	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K6V27_RS09780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K6V27_RS09795	COG0791	NLP P60 protein
K6V27_RS09810	COG0612	Peptidase, M16
K6V27_RS09815	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K6V27_RS09820	COG1597	lipid kinase activity
K6V27_RS09825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K6V27_RS09840	COG1136	(ABC) transporter
K6V27_RS09860	COG2211	Major facilitator Superfamily
K6V27_RS09865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K6V27_RS09880	COG1674	ftsk spoiiie
K6V27_RS09890	COG0492	ferredoxin-NADP+ reductase activity
K6V27_RS09895	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS09925	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K6V27_RS09925	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K6V27_RS09935	COG1234	tRNA 3'-trailer cleavage
K6V27_RS09955	COG3956	TIGRFAM MazG family protein
K6V27_RS09970	COG0525	valine-tRNA ligase activity
K6V27_RS09975	COG0784	Response regulator, receiver
K6V27_RS09975	COG2205	protein histidine kinase activity
K6V27_RS09975	COG5002	protein histidine kinase activity
K6V27_RS09990	COG1629	transport
K6V27_RS09990	COG4206	TonB-dependent receptor
K6V27_RS10015	COG0653	protein targeting
K6V27_RS10020	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
K6V27_RS10030	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
K6V27_RS10050	COG1253	flavin adenine dinucleotide binding
K6V27_RS10060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K6V27_RS10070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K6V27_RS10075	COG2204	response regulator
K6V27_RS10115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K6V27_RS10115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K6V27_RS10130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
K6V27_RS10135	COG0563	adenylate kinase activity
K6V27_RS10140	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K6V27_RS10145	COG1496	oxidoreductase activity
K6V27_RS10165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS10170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS10180	COG0477	Major facilitator Superfamily
K6V27_RS10180	COG2814	Major facilitator Superfamily
K6V27_RS10185	COG0457	Tetratricopeptide repeat
K6V27_RS10190	COG2706	6-phosphogluconolactonase activity
K6V27_RS10350	COG4206	TonB-dependent receptor
K6V27_RS10350	COG1629	transport
K6V27_RS10415	COG3142	Participates in the control of copper homeostasis
K6V27_RS10420	COG1418	mRNA catabolic process
K6V27_RS10450	COG1070	Carbohydrate kinase
K6V27_RS10455	COG1063	alcohol dehydrogenase
K6V27_RS10460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K6V27_RS10485	COG1333	cytochrome c biogenesis protein
K6V27_RS10485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6V27_RS10530	COG3328	transposase activity
K6V27_RS10620	COG0673	inositol 2-dehydrogenase activity
K6V27_RS10630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K6V27_RS10635	COG2832	Protein of unknown function (DUF454)
K6V27_RS10645	COG0602	queuosine metabolic process
K6V27_RS10650	COG0247	lactate metabolic process
K6V27_RS10655	COG1139	Iron-sulfur cluster binding protein
K6V27_RS10665	COG0351	phosphomethylpyrimidine kinase
K6V27_RS10690	COG4589	Belongs to the CDS family
K6V27_RS10700	COG2304	oxidoreductase activity
K6V27_RS10720	COG1393	Belongs to the ArsC family
K6V27_RS10730	COG1629	transport
K6V27_RS10730	COG4206	TonB-dependent receptor
K6V27_RS10745	COG2233	PERMEase
K6V27_RS10750	COG1509	lysine 2,3-aminomutase activity
K6V27_RS10760	COG1115	amino acid carrier protein
K6V27_RS10800	COG1285	pathogenesis
K6V27_RS10810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K6V27_RS10815	COG0741	lytic transglycosylase activity
K6V27_RS10815	COG1388	LysM domain
K6V27_RS10865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6V27_RS10880	COG0534	Mate efflux family protein
K6V27_RS10890	COG0564	pseudouridine synthase activity
K6V27_RS10915	COG0346	lactoylglutathione lyase activity
K6V27_RS10925	COG0653	protein targeting
K6V27_RS10975	COG1063	alcohol dehydrogenase
K6V27_RS11005	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
K6V27_RS11010	COG4804	nuclease activity
K6V27_RS11015	COG0732	type I restriction modification DNA specificity domain
K6V27_RS11060	COG1910	domain protein
K6V27_RS11085	COG4974	Belongs to the 'phage' integrase family
K6V27_RS11120	COG1401	restriction endodeoxyribonuclease activity
K6V27_RS11130	COG5290	Psort location Cytoplasmic, score
K6V27_RS11180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K6V27_RS11185	COG5002	protein histidine kinase activity
K6V27_RS11185	COG0784	Response regulator, receiver
K6V27_RS11190	COG2910	NAD(P)H-binding
K6V27_RS11200	COG4864	UPF0365 protein
K6V27_RS11215	COG0037	tRNA processing
K6V27_RS11225	COG1477	protein flavinylation
K6V27_RS11230	COG1971	Probably functions as a manganese efflux pump
K6V27_RS11245	COG0463	Glycosyl transferase, family 2
K6V27_RS11260	COG3279	Response regulator of the LytR AlgR family
K6V27_RS11285	COG1595	DNA-templated transcription, initiation
K6V27_RS11290	COG0148	phosphopyruvate hydratase activity
K6V27_RS11300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K6V27_RS11325	COG5433	transposase activity
K6V27_RS11330	COG1082	Xylose isomerase domain protein TIM barrel
K6V27_RS11335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K6V27_RS11340	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6V27_RS11345	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K6V27_RS11350	COG4651	solute:proton antiporter activity
K6V27_RS11350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K6V27_RS11360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K6V27_RS11365	COG0193	aminoacyl-tRNA hydrolase activity
K6V27_RS11370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K6V27_RS11380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K6V27_RS11385	COG1862	Preprotein translocase
K6V27_RS11395	COG0237	dephospho-CoA kinase activity
K6V27_RS11410	COG0542	response to heat
K6V27_RS11420	COG0583	DNA-binding transcription factor activity
K6V27_RS11435	COG0443	Heat shock 70 kDa protein
K6V27_RS11470	COG2855	membrane
K6V27_RS11475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K6V27_RS11480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K6V27_RS11500	COG0443	Heat shock 70 kDa protein
K6V27_RS11565	COG0326	Molecular chaperone. Has ATPase activity
K6V27_RS11590	COG3119	arylsulfatase activity
K6V27_RS11600	COG0702	epimerase
K6V27_RS11605	COG4771	TonB-dependent receptor
K6V27_RS11620	COG0306	phosphate transporter
K6V27_RS11630	COG0586	Pfam SNARE associated Golgi protein
K6V27_RS11680	COG0038	chloride channel
K6V27_RS11685	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K6V27_RS11710	COG3119	arylsulfatase activity
K6V27_RS11720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K6V27_RS11735	COG0702	epimerase
K6V27_RS11740	COG4771	TonB-dependent receptor
K6V27_RS11750	COG5434	Belongs to the glycosyl hydrolase 28 family
K6V27_RS11760	COG0745	RESPONSE REGULATOR receiver
K6V27_RS11760	COG3292	Two component regulator propeller
K6V27_RS11760	COG2205	protein histidine kinase activity
K6V27_RS11765	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
K6V27_RS11770	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K6V27_RS11790	COG1404	Belongs to the peptidase S8 family
K6V27_RS11790	COG4935	Belongs to the peptidase S8 family
K6V27_RS11840	COG0156	8-amino-7-oxononanoate synthase activity
K6V27_RS11850	COG3250	beta-galactosidase activity
K6V27_RS11865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6V27_RS11870	COG1629	transport
K6V27_RS11870	COG4206	TonB-dependent receptor
K6V27_RS11880	COG3292	Two component regulator propeller
K6V27_RS11880	COG2205	protein histidine kinase activity
K6V27_RS11880	COG0745	RESPONSE REGULATOR receiver
K6V27_RS11905	COG1760	l-serine dehydratase
K6V27_RS11910	COG0598	Magnesium transport protein CorA
K6V27_RS11915	COG1193	negative regulation of DNA recombination
K6V27_RS11935	COG4771	TonB-dependent receptor
K6V27_RS11950	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS11965	COG3250	beta-galactosidase activity
K6V27_RS11975	COG4771	TonB-dependent receptor
K6V27_RS11990	COG0668	transmembrane transport
K6V27_RS11995	COG1523	belongs to the glycosyl hydrolase 13 family
K6V27_RS12005	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
K6V27_RS12015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS12025	COG1538	Outer membrane efflux protein
K6V27_RS12035	COG0456	acetyltransferase
K6V27_RS12045	COG3189	MarR family transcriptional regulator
K6V27_RS12050	COG0561	phosphatase activity
K6V27_RS12055	COG1169	isochorismate synthase
K6V27_RS12060	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K6V27_RS12065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K6V27_RS12070	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS12090	COG1629	transport
K6V27_RS12090	COG4206	TonB-dependent receptor
K6V27_RS12140	COG0783	Belongs to the Dps family
K6V27_RS12145	COG0583	DNA-binding transcription factor activity
K6V27_RS12155	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K6V27_RS12175	COG1595	DNA-templated transcription, initiation
K6V27_RS12185	COG4771	TonB-dependent receptor
K6V27_RS12195	COG0584	glycerophosphoryl diester phosphodiesterase
K6V27_RS12200	COG0584	glycerophosphoryl diester phosphodiesterase
K6V27_RS12205	COG2271	Major facilitator Superfamily
K6V27_RS12250	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS12255	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6V27_RS12260	COG1882	Formate acetyltransferase
K6V27_RS12285	COG0500	methyltransferase
K6V27_RS12290	COG2918	glutathione biosynthetic process
K6V27_RS12290	COG0189	ligase activity
K6V27_RS12295	COG0534	Mate efflux family protein
K6V27_RS12330	COG4804	nuclease activity
K6V27_RS12345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K6V27_RS12390	COG1028	Short-chain dehydrogenase reductase Sdr
K6V27_RS12395	COG1082	Xylose isomerase domain protein TIM barrel
K6V27_RS12400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K6V27_RS12450	COG4974	Belongs to the 'phage' integrase family
K6V27_RS12515	COG0202	RNA polymerase activity
K6V27_RS12655	COG1475	DNA binding
K6V27_RS12670	COG1192	Involved in chromosome partitioning
K6V27_RS12690	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K6V27_RS12705	COG0629	single-stranded DNA binding
K6V27_RS12735	COG3279	Response regulator of the LytR AlgR family
K6V27_RS12755	COG0739	heme binding
K6V27_RS12755	COG0741	lytic transglycosylase activity
K6V27_RS12755	COG1196	nuclear chromosome segregation
K6V27_RS12825	COG1388	LysM domain
K6V27_RS12825	COG1705	Flagellar rod assembly protein muramidase FlgJ
K6V27_RS12945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6V27_RS12990	COG0561	phosphatase activity
K6V27_RS12995	COG1629	transport
K6V27_RS13010	COG0248	Ppx GppA phosphatase
K6V27_RS13045	COG4245	von Willebrand factor, type A
K6V27_RS13050	COG2304	oxidoreductase activity
K6V27_RS13055	COG4245	von Willebrand factor, type A
K6V27_RS13080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K6V27_RS13265	COG1629	transport
K6V27_RS13265	COG4206	TonB-dependent receptor
K6V27_RS13285	COG3250	beta-galactosidase activity
K6V27_RS13300	COG1629	transport
K6V27_RS13300	COG4206	TonB-dependent receptor
K6V27_RS13320	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS13330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K6V27_RS13340	COG1253	flavin adenine dinucleotide binding
K6V27_RS13345	COG0501	Belongs to the peptidase M48B family
K6V27_RS13370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6V27_RS13375	COG0482	sulfurtransferase activity
K6V27_RS13380	COG2197	response regulator
K6V27_RS13390	COG1757	Na H antiporter
K6V27_RS13405	COG2814	Major facilitator Superfamily
K6V27_RS13410	COG4953	penicillin-binding protein 1C
K6V27_RS13415	COG2373	Large extracellular alpha-helical protein
K6V27_RS13420	COG0545	Peptidyl-prolyl cis-trans isomerase
K6V27_RS13495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K6V27_RS13500	COG0646	methionine synthase
K6V27_RS13500	COG1410	methionine synthase
K6V27_RS13505	COG0778	Nitroreductase
K6V27_RS13510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K6V27_RS13520	COG0572	uridine kinase
K6V27_RS13530	COG4232	protein-disulfide reductase activity
K6V27_RS13535	COG1741	Belongs to the pirin family
K6V27_RS13550	COG1629	transport
K6V27_RS13555	COG0702	epimerase
K6V27_RS13580	COG2271	Major facilitator Superfamily
K6V27_RS13600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K6V27_RS13605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K6V27_RS13610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K6V27_RS13615	COG0131	Imidazoleglycerol-phosphate dehydratase
K6V27_RS13625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6V27_RS13625	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K6V27_RS13630	COG4771	TonB-dependent receptor
K6V27_RS13680	COG1773	rubredoxin
K6V27_RS13680	COG1592	Rubrerythrin
K6V27_RS13710	COG3591	Belongs to the peptidase S1B family
K6V27_RS13715	COG3591	Belongs to the peptidase S1B family
K6V27_RS13720	COG0641	radical SAM
K6V27_RS13750	COG0420	3'-5' exonuclease activity
K6V27_RS13760	COG1408	metallophosphoesterase
K6V27_RS13775	COG0646	methionine synthase
K6V27_RS13775	COG1410	methionine synthase
K6V27_RS13785	COG0463	Glycosyl transferase, family 2
K6V27_RS13790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K6V27_RS13800	COG1032	radical SAM domain protein
K6V27_RS13820	COG0363	glucosamine-6-phosphate deaminase activity
K6V27_RS13825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6V27_RS13860	COG0745	RESPONSE REGULATOR receiver
K6V27_RS13860	COG2205	protein histidine kinase activity
K6V27_RS13860	COG3292	Two component regulator propeller
K6V27_RS13865	COG1629	transport
K6V27_RS13870	COG0702	epimerase
K6V27_RS13885	COG4771	TonB-dependent receptor
K6V27_RS13925	COG3328	transposase activity
K6V27_RS13945	COG0811	peptide transport
K6V27_RS13950	COG0848	biopolymer transport protein
K6V27_RS14000	COG1131	(ABC) transporter
K6V27_RS14035	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6V27_RS14075	COG0508	dehydrogenase complex catalyzes the overall conversion of
K6V27_RS14080	COG0022	dehydrogenase e1 component
K6V27_RS14090	COG2264	protein methyltransferase activity
K6V27_RS14105	COG4206	TonB-dependent receptor
K6V27_RS14105	COG1629	transport
K6V27_RS14120	COG0590	tRNA wobble adenosine to inosine editing
K6V27_RS14125	COG0673	inositol 2-dehydrogenase activity
K6V27_RS14150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
K6V27_RS14195	COG2425	protein containing a von Willebrand factor type A (vWA) domain
K6V27_RS14210	COG1501	Belongs to the glycosyl hydrolase 31 family
K6V27_RS14215	COG5012	cobalamin binding
K6V27_RS14245	COG0698	ribose 5-phosphate isomerase
K6V27_RS14250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K6V27_RS14265	COG1070	Carbohydrate kinase
K6V27_RS14270	COG2160	L-arabinose isomerase activity
K6V27_RS14320	COG0702	epimerase
K6V27_RS14325	COG4206	TonB-dependent receptor
K6V27_RS14325	COG1629	transport
K6V27_RS14330	COG0702	epimerase
K6V27_RS14335	COG1629	transport
K6V27_RS14335	COG4206	TonB-dependent receptor
K6V27_RS14345	COG3292	Two component regulator propeller
K6V27_RS14345	COG2205	protein histidine kinase activity
K6V27_RS14345	COG0745	RESPONSE REGULATOR receiver
K6V27_RS14350	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS14360	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS14365	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K6V27_RS14380	COG1482	cell wall glycoprotein biosynthetic process
K6V27_RS14420	COG1216	Glycosyl transferase, family 2
K6V27_RS14425	COG1216	Glycosyl transferase, family 2
K6V27_RS14440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6V27_RS14470	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K6V27_RS14475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6V27_RS14495	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS14535	COG4221	oxidoreductase activity
K6V27_RS14545	COG1218	3'(2'),5'-bisphosphate nucleotidase
K6V27_RS14550	COG0471	metal ion transport
K6V27_RS14550	COG3273	potassium ion transport
K6V27_RS14555	COG0529	Catalyzes the synthesis of activated sulfate
K6V27_RS14560	COG0175	sulfate reduction
K6V27_RS14565	COG2895	sulfate adenylyltransferase (ATP) activity
K6V27_RS14585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K6V27_RS14590	COG0242	peptide deformylase activity
K6V27_RS14600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K6V27_RS14605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K6V27_RS14610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K6V27_RS14615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K6V27_RS14625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K6V27_RS14630	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K6V27_RS14635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
K6V27_RS14635	COG0674	pyruvate-flavodoxin oxidoreductase activity
K6V27_RS14635	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K6V27_RS14635	COG1013	pyruvate-flavodoxin oxidoreductase activity
K6V27_RS14645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K6V27_RS14660	COG1940	carbohydrate kinase activity
K6V27_RS14665	COG2081	HI0933 family
K6V27_RS14675	COG2814	Major facilitator Superfamily
K6V27_RS14685	COG4771	TonB-dependent receptor
K6V27_RS14720	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K6V27_RS14720	COG2755	lipolytic protein G-D-S-L family
K6V27_RS14755	COG4771	TonB-dependent receptor
K6V27_RS14830	COG1629	transport
K6V27_RS14855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS14860	COG0657	acetylesterase activity
K6V27_RS14860	COG2755	lipolytic protein G-D-S-L family
K6V27_RS14870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS14875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS14880	COG3250	beta-galactosidase activity
K6V27_RS14900	COG1091	dTDP-4-dehydrorhamnose reductase activity
K6V27_RS14950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K6V27_RS14960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K6V27_RS14990	COG4771	TonB-dependent receptor
K6V27_RS14995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6V27_RS15000	COG0484	heat shock protein binding
K6V27_RS15005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K6V27_RS15010	COG0488	(ABC) transporter
K6V27_RS15025	COG2183	response to ionizing radiation
K6V27_RS15030	COG2202	Pas domain
K6V27_RS15030	COG2205	protein histidine kinase activity
K6V27_RS15035	COG0737	Belongs to the 5'-nucleotidase family
K6V27_RS15325	COG0490	domain, Protein
K6V27_RS15325	COG2985	domain, Protein
K6V27_RS15330	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
K6V27_RS15340	COG0318	PFAM AMP-dependent synthetase and ligase
K6V27_RS15345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6V27_RS15350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
K6V27_RS15355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
K6V27_RS15360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K6V27_RS15370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K6V27_RS15380	COG2837	iron assimilation
K6V27_RS15385	COG2135	peptidase activity
K6V27_RS15390	COG3279	Response regulator of the LytR AlgR family
K6V27_RS15400	COG1136	(ABC) transporter
K6V27_RS15400	COG0577	efflux transmembrane transporter activity
K6V27_RS15405	COG1136	(ABC) transporter
K6V27_RS15410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS15440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K6V27_RS15450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K6V27_RS15475	COG0501	Belongs to the peptidase M48B family
K6V27_RS15480	COG1704	LemA family
K6V27_RS15495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K6V27_RS15500	COG2885	chlorophyll binding
K6V27_RS15505	COG0534	Mate efflux family protein
K6V27_RS15510	COG0657	acetylesterase activity
K6V27_RS15510	COG2755	lipolytic protein G-D-S-L family
K6V27_RS15520	COG1162	GTPase activity
K6V27_RS15540	COG0488	(ABC) transporter
K6V27_RS15570	COG1215	transferase activity, transferring glycosyl groups
K6V27_RS15575	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS15580	COG0438	transferase activity, transferring glycosyl groups
K6V27_RS15585	COG1442	glycosyl transferase family 8
K6V27_RS15595	COG2244	polysaccharide biosynthetic process
K6V27_RS15600	COG1442	glycosyl transferase family 8
K6V27_RS15600	COG1216	Glycosyl transferase, family 2
K6V27_RS15640	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS15650	COG1215	transferase activity, transferring glycosyl groups
K6V27_RS15685	COG1805	sodium ion transport
K6V27_RS15690	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6V27_RS15700	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K6V27_RS15705	COG2871	sodium ion transport
K6V27_RS15710	COG0513	Belongs to the DEAD box helicase family
K6V27_RS15715	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K6V27_RS15730	COG1739	Uncharacterized protein family UPF0029
K6V27_RS15745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K6V27_RS15745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K6V27_RS15750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K6V27_RS15755	COG0357	Ribosomal RNA small subunit methyltransferase G
K6V27_RS15800	COG2217	Heavy metal translocating P-type atpase
K6V27_RS15810	COG0321	lipoyl(octanoyl) transferase activity
K6V27_RS15840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K6V27_RS15850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K6V27_RS15865	COG1678	Uncharacterized ACR, COG1678
K6V27_RS15885	COG3275	phosphorelay sensor kinase activity
K6V27_RS15915	COG3969	phosphoadenosine phosphosulfate
K6V27_RS15920	COG1475	DNA binding
K6V27_RS15965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6V27_RS15985	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K6V27_RS15990	COG1074	ATP-dependent DNA helicase activity
K6V27_RS16005	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS16030	COG4206	TonB-dependent receptor
K6V27_RS16030	COG1629	transport
K6V27_RS16060	COG4771	TonB-dependent receptor
K6V27_RS16095	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
K6V27_RS16100	COG3537	Alpha-1,2-mannosidase
K6V27_RS16115	COG1629	transport
K6V27_RS16120	COG0702	epimerase
K6V27_RS16130	COG4206	TonB-dependent receptor
K6V27_RS16130	COG1629	transport
K6V27_RS16135	COG0702	epimerase
K6V27_RS16160	COG3408	Glycogen debranching enzyme
K6V27_RS16180	COG1028	Short-chain dehydrogenase reductase Sdr
K6V27_RS16190	COG3408	Glycogen debranching enzyme
K6V27_RS16200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
K6V27_RS16210	COG0167	dihydroorotate dehydrogenase activity
K6V27_RS16215	COG0657	acetylesterase activity
K6V27_RS16215	COG2755	lipolytic protein G-D-S-L family
K6V27_RS16265	COG5002	protein histidine kinase activity
K6V27_RS16265	COG2205	protein histidine kinase activity
K6V27_RS16265	COG0784	Response regulator, receiver
K6V27_RS16275	COG3250	beta-galactosidase activity
K6V27_RS16295	COG3250	beta-galactosidase activity
K6V27_RS16305	COG0745	RESPONSE REGULATOR receiver
K6V27_RS16310	COG5002	protein histidine kinase activity
K6V27_RS16350	COG3292	Two component regulator propeller
K6V27_RS16350	COG2205	protein histidine kinase activity
K6V27_RS16350	COG0745	RESPONSE REGULATOR receiver
K6V27_RS16380	COG2966	Psort location CytoplasmicMembrane, score
K6V27_RS16395	COG0300	oxidoreductase activity
K6V27_RS16405	COG1011	Hydrolase
K6V27_RS16425	COG1595	DNA-templated transcription, initiation
K6V27_RS16455	COG4206	TonB-dependent receptor
K6V27_RS16465	COG3292	Two component regulator propeller
K6V27_RS16465	COG0745	RESPONSE REGULATOR receiver
K6V27_RS16465	COG2205	protein histidine kinase activity
K6V27_RS16480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS16495	COG0442	prolyl-tRNA aminoacylation
K6V27_RS16500	COG0745	RESPONSE REGULATOR receiver
K6V27_RS16505	COG2205	protein histidine kinase activity
K6V27_RS16540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K6V27_RS16550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K6V27_RS16555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K6V27_RS16565	COG0552	protein localization to endoplasmic reticulum
K6V27_RS16570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K6V27_RS16575	COG0776	regulation of translation
K6V27_RS16580	COG0776	regulation of translation
K6V27_RS16585	COG0714	Associated with various cellular activities
K6V27_RS16600	COG2304	oxidoreductase activity
K6V27_RS16650	COG0326	Molecular chaperone. Has ATPase activity
K6V27_RS16675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K6V27_RS16680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K6V27_RS16685	COG0336	Belongs to the RNA methyltransferase TrmD family
K6V27_RS16690	COG0167	dihydroorotate dehydrogenase activity
K6V27_RS16695	COG0543	2 iron, 2 sulfur cluster binding
K6V27_RS16710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K6V27_RS16740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K6V27_RS16760	COG1132	(ABC) transporter
K6V27_RS16790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K6V27_RS16795	COG1597	lipid kinase activity
K6V27_RS16800	COG0156	8-amino-7-oxononanoate synthase activity
K6V27_RS16815	COG4771	TonB-dependent receptor
K6V27_RS16865	COG1136	(ABC) transporter
K6V27_RS16890	COG3852	Histidine kinase
K6V27_RS16910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K6V27_RS16915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K6V27_RS16935	COG0560	Phosphoserine phosphatase
K6V27_RS16935	COG3830	Belongs to the UPF0237 family
K6V27_RS16940	COG0513	Belongs to the DEAD box helicase family
K6V27_RS16970	COG0246	Mannitol dehydrogenase
K6V27_RS16980	COG1904	glucuronate isomerase
K6V27_RS16995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K6V27_RS17015	COG0784	Response regulator, receiver
K6V27_RS17015	COG2198	Histidine kinase
K6V27_RS17015	COG2205	protein histidine kinase activity
K6V27_RS17020	COG3015	lipoprotein NlpE involved in copper resistance
K6V27_RS17050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6V27_RS17065	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K6V27_RS17075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K6V27_RS17085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K6V27_RS17085	COG3153	acetyltransferase
K6V27_RS17090	COG0798	PFAM Bile acid sodium symporter
K6V27_RS17135	COG0477	Major facilitator Superfamily
K6V27_RS17135	COG2814	Major facilitator Superfamily
K6V27_RS17140	COG2115	Belongs to the xylose isomerase family
K6V27_RS17155	COG0351	phosphomethylpyrimidine kinase
K6V27_RS17160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K6V27_RS17165	COG0045	succinate-CoA ligase (ADP-forming) activity
K6V27_RS17170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K6V27_RS17215	COG2326	polyphosphate kinase activity
K6V27_RS17225	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
K6V27_RS17250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K6V27_RS17265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K6V27_RS17270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K6V27_RS17280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6V27_RS17305	COG3292	Two component regulator propeller
K6V27_RS17305	COG2205	protein histidine kinase activity
K6V27_RS17305	COG0745	RESPONSE REGULATOR receiver
K6V27_RS17325	COG3153	acetyltransferase
K6V27_RS17330	COG3250	beta-galactosidase activity
K6V27_RS17335	COG3119	arylsulfatase activity
K6V27_RS17345	COG4206	TonB-dependent receptor
K6V27_RS17345	COG1629	transport
K6V27_RS17370	COG2205	protein histidine kinase activity
K6V27_RS17375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K6V27_RS17390	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K6V27_RS17405	COG0540	Belongs to the ATCase OTCase family
K6V27_RS17410	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
K6V27_RS17425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K6V27_RS17430	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K6V27_RS17435	COG2985	domain, Protein
K6V27_RS17475	COG2207	Transcriptional regulator
K6V27_RS17500	COG2431	L-lysine efflux transmembrane transporter activity
K6V27_RS17505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K6V27_RS17515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K6V27_RS17520	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K6V27_RS17525	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K6V27_RS17530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K6V27_RS17535	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K6V27_RS17540	COG0356	it plays a direct role in the translocation of protons across the membrane
K6V27_RS17550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K6V27_RS17555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K6V27_RS17580	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS17595	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K6V27_RS17615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K6V27_RS17625	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K6V27_RS17635	COG0534	Mate efflux family protein
K6V27_RS17645	COG1136	(ABC) transporter
K6V27_RS17680	COG1151	hydroxylamine reductase activity
K6V27_RS17685	COG2233	PERMEase
K6V27_RS17690	COG3263	regulation of cellular component size
K6V27_RS17695	COG0318	PFAM AMP-dependent synthetase and ligase
K6V27_RS17700	COG1082	Xylose isomerase domain protein TIM barrel
K6V27_RS17705	COG0745	RESPONSE REGULATOR receiver
K6V27_RS17710	COG5002	protein histidine kinase activity
K6V27_RS17730	COG3118	belongs to the thioredoxin family
K6V27_RS17735	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K6V27_RS17780	COG2249	NAD(P)H dehydrogenase (quinone) activity
K6V27_RS17800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS17830	COG0681	Belongs to the peptidase S26 family
K6V27_RS17905	COG5002	protein histidine kinase activity
K6V27_RS17915	COG0352	thiamine-phosphate diphosphorylase activity
K6V27_RS17920	COG2022	thiamine diphosphate biosynthetic process
K6V27_RS17925	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K6V27_RS17930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K6V27_RS17935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K6V27_RS17940	COG0352	thiamine-phosphate diphosphorylase activity
K6V27_RS17955	COG0574	Belongs to the PEP-utilizing enzyme family
K6V27_RS17955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K6V27_RS17960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K6V27_RS17965	COG0564	pseudouridine synthase activity
K6V27_RS17985	COG0024	Methionine aminopeptidase
K6V27_RS18005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K6V27_RS18015	COG0481	GTPase activity
K6V27_RS18020	COG4974	Belongs to the 'phage' integrase family
K6V27_RS18090	COG4974	Belongs to the 'phage' integrase family
K6V27_RS18120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K6V27_RS18120	COG0551	DNA topoisomerase type I activity
K6V27_RS18140	COG2205	protein histidine kinase activity
K6V27_RS18140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6V27_RS18140	COG0784	Response regulator, receiver
K6V27_RS18140	COG2198	Histidine kinase
K6V27_RS18175	COG3344	reverse transcriptase
K6V27_RS18180	COG3344	reverse transcriptase
K6V27_RS18185	COG3344	reverse transcriptase
K6V27_RS18285	COG0358	DNA primase activity
K6V27_RS18305	COG4974	Belongs to the 'phage' integrase family
K6V27_RS18315	COG4974	Belongs to the 'phage' integrase family
K6V27_RS18375	COG0708	Exodeoxyribonuclease III
K6V27_RS18390	COG0217	transcriptional regulatory protein
K6V27_RS18395	COG0072	phenylalanine-tRNA ligase activity
K6V27_RS18395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K6V27_RS18400	COG0305	Participates in initiation and elongation during chromosome replication
K6V27_RS18405	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K6V27_RS18410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K6V27_RS18415	COG4657	Part of a membrane complex involved in electron transport
K6V27_RS18420	COG4660	Part of a membrane complex involved in electron transport
K6V27_RS18425	COG4659	FMN binding
K6V27_RS18430	COG4658	electron transport chain
K6V27_RS18435	COG4656	Part of a membrane complex involved in electron transport
K6V27_RS18565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K6V27_RS18585	COG1086	Polysaccharide biosynthesis protein
K6V27_RS18640	COG0504	CTP synthase activity
K6V27_RS18645	COG0706	membrane insertase activity
K6V27_RS18650	COG0534	Mate efflux family protein
K6V27_RS18655	COG1506	peptidase
K6V27_RS18655	COG0823	Involved in the tonB-independent uptake of proteins
K6V27_RS18675	COG1983	PspC domain protein
K6V27_RS18680	COG1695	Transcriptional regulator
K6V27_RS18690	COG3104	oligopeptide transport
K6V27_RS18695	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K6V27_RS18705	COG1388	LysM domain
K6V27_RS18705	COG3942	CHAP domain
K6V27_RS18735	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K6V27_RS18740	COG0556	nucleotide-excision repair
K6V27_RS18755	COG2949	membrane
K6V27_RS18775	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6V27_RS18805	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K6V27_RS18815	COG0842	Transport permease protein
K6V27_RS18820	COG0842	Transport permease protein
K6V27_RS18825	COG1131	(ABC) transporter
K6V27_RS18840	COG2207	Transcriptional regulator
K6V27_RS18840	COG1917	Cupin 2, conserved barrel domain protein
K6V27_RS18850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K6V27_RS18855	COG0505	Belongs to the CarA family
K6V27_RS18865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K6V27_RS18870	COG0070	glutamate synthase
K6V27_RS18870	COG0069	glutamate synthase activity
K6V27_RS18870	COG0067	glutamate synthase
K6V27_RS18880	COG0367	asparagine synthase
K6V27_RS18895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K6V27_RS18900	COG0436	Aminotransferase
K6V27_RS18910	COG0347	Belongs to the P(II) protein family
K6V27_RS18915	COG0004	ammonium transporteR
K6V27_RS18930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K6V27_RS18940	COG0471	metal ion transport
K6V27_RS18940	COG0490	domain, Protein
K6V27_RS18950	COG1979	alcohol dehydrogenase
K6V27_RS18960	COG0133	tryptophan synthase activity
K6V27_RS18965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K6V27_RS18975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K6V27_RS18980	COG0134	indole-3-glycerol-phosphate synthase activity
K6V27_RS18985	COG0135	phosphoribosylanthranilate isomerase activity
K6V27_RS18990	COG0159	tryptophan synthase activity
K6V27_RS18995	COG0252	asparaginase activity
K6V27_RS19005	COG3292	Two component regulator propeller
K6V27_RS19005	COG0745	RESPONSE REGULATOR receiver
K6V27_RS19005	COG2205	protein histidine kinase activity
K6V27_RS19010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K6V27_RS19020	COG0110	maltose O-acetyltransferase activity
K6V27_RS19025	COG2197	response regulator
K6V27_RS19035	COG0138	bifunctional purine biosynthesis protein purh
K6V27_RS19040	COG0716	FMN binding
K6V27_RS19080	COG1132	(ABC) transporter
K6V27_RS19095	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS19105	COG4771	TonB-dependent receptor
K6V27_RS19115	COG4771	TonB-dependent receptor
K6V27_RS19125	COG0490	domain, Protein
K6V27_RS19125	COG2985	domain, Protein
K6V27_RS19130	COG1230	cation diffusion facilitator family transporter
K6V27_RS19145	COG4771	TonB-dependent receptor
K6V27_RS19150	COG1429	ligase activity, forming nitrogen-metal bonds
K6V27_RS19185	COG1609	Transcriptional regulator
K6V27_RS19190	COG2721	sulfolactate sulfo-lyase activity
K6V27_RS19270	COG1733	regulation of RNA biosynthetic process
K6V27_RS19280	COG2205	protein histidine kinase activity
K6V27_RS19280	COG2198	Histidine kinase
K6V27_RS19280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6V27_RS19280	COG0784	Response regulator, receiver
K6V27_RS19290	COG3275	phosphorelay sensor kinase activity
K6V27_RS19315	COG0228	four-way junction DNA binding
K6V27_RS19320	COG2188	Transcriptional regulator
K6V27_RS19325	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
K6V27_RS19335	COG1070	Carbohydrate kinase
K6V27_RS19345	COG0738	Major facilitator superfamily
K6V27_RS19390	COG2207	Transcriptional regulator
K6V27_RS19405	COG1177	transmembrane transport
K6V27_RS19410	COG1176	ABC-type spermidine putrescine transport system, permease component I
K6V27_RS19415	COG3842	ATPase activity
K6V27_RS19420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K6V27_RS19425	COG0058	SHG alpha-glucan phosphorylase activity
K6V27_RS19435	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K6V27_RS19455	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
K6V27_RS19480	COG1725	Transcriptional regulator
K6V27_RS19490	COG1131	(ABC) transporter
K6V27_RS19535	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K6V27_RS19540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K6V27_RS19545	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS19560	COG1295	ribonuclease BN
K6V27_RS19575	COG2972	Histidine kinase
K6V27_RS19580	COG3279	Response regulator of the LytR AlgR family
K6V27_RS19585	COG0704	Plays a role in the regulation of phosphate uptake
K6V27_RS19590	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K6V27_RS19595	COG0581	inorganic phosphate transmembrane transporter activity
K6V27_RS19600	COG0573	inorganic phosphate transmembrane transporter activity
K6V27_RS19610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K6V27_RS19620	COG0586	Pfam SNARE associated Golgi protein
K6V27_RS19630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
K6V27_RS19645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K6V27_RS19650	COG0167	dihydroorotate dehydrogenase activity
K6V27_RS19655	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K6V27_RS19700	COG1442	glycosyl transferase family 8
K6V27_RS19700	COG1216	Glycosyl transferase, family 2
K6V27_RS19710	COG5039	Polysaccharide pyruvyl transferase
K6V27_RS19755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K6V27_RS19760	COG0497	DNA recombination
K6V27_RS19775	COG0592	DNA-directed DNA polymerase activity
K6V27_RS19800	COG0321	lipoyl(octanoyl) transferase activity
K6V27_RS19800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K6V27_RS19805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K6V27_RS19815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K6V27_RS19820	COG0156	8-amino-7-oxononanoate synthase activity
K6V27_RS19835	COG0019	diaminopimelate decarboxylase activity
K6V27_RS19840	COG0527	aspartate kinase activity
K6V27_RS19845	COG2884	Cell division ATP-binding protein ftsE
K6V27_RS19850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K6V27_RS19850	COG0140	phosphoribosyl-ATP diphosphatase activity
K6V27_RS19855	COG0107	imidazoleglycerol-phosphate synthase activity
K6V27_RS19860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K6V27_RS19865	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K6V27_RS19870	COG0788	formyltetrahydrofolate deformylase activity
K6V27_RS19885	COG0693	protein deglycase activity
K6V27_RS19890	COG0656	L-ascorbic acid biosynthetic process
K6V27_RS19910	COG0534	Mate efflux family protein
K6V27_RS19915	COG2076	Multidrug Resistance protein
K6V27_RS19930	COG2885	chlorophyll binding
K6V27_RS19930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K6V27_RS19965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
K6V27_RS19980	COG2814	Major facilitator Superfamily
K6V27_RS20005	COG1309	transcriptional regulator
K6V27_RS20010	COG1924	4 iron, 4 sulfur cluster binding
K6V27_RS20015	COG0823	Involved in the tonB-independent uptake of proteins
K6V27_RS20015	COG1506	peptidase
K6V27_RS20015	COG4946	Tricorn protease homolog
K6V27_RS20030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K6V27_RS20035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K6V27_RS20050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6V27_RS20060	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
K6V27_RS20075	COG4771	TonB-dependent receptor
K6V27_RS20135	COG1312	Catalyzes the dehydration of D-mannonate
K6V27_RS20140	COG1028	Short-chain dehydrogenase reductase Sdr
K6V27_RS20145	COG1609	Transcriptional regulator
K6V27_RS20160	COG1929	Belongs to the glycerate kinase type-1 family
K6V27_RS20165	COG2223	nitrite transmembrane transporter activity
K6V27_RS20175	COG4771	TonB-dependent receptor
K6V27_RS20185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K6V27_RS20185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K6V27_RS20200	COG2226	methyltransferase
K6V27_RS20210	COG0784	Response regulator, receiver
K6V27_RS20210	COG5002	protein histidine kinase activity
K6V27_RS20215	COG0511	ligase activity, forming carbon-carbon bonds
K6V27_RS20220	COG0439	Biotin carboxylase
K6V27_RS20225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6V27_RS20240	COG1620	l-lactate permease
K6V27_RS20245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
K6V27_RS20250	COG1690	Belongs to the RtcB family
K6V27_RS20260	COG3279	Response regulator of the LytR AlgR family
K6V27_RS20290	COG0110	maltose O-acetyltransferase activity
K6V27_RS20300	COG0577	efflux transmembrane transporter activity
K6V27_RS20305	COG1136	(ABC) transporter
K6V27_RS20305	COG0577	efflux transmembrane transporter activity
K6V27_RS20330	COG0628	permease
K6V27_RS20335	COG1215	transferase activity, transferring glycosyl groups
K6V27_RS20345	COG0189	ligase activity
K6V27_RS20345	COG0569	domain protein
K6V27_RS20350	COG1136	(ABC) transporter
K6V27_RS20350	COG0577	efflux transmembrane transporter activity
K6V27_RS20355	COG0436	Aminotransferase
K6V27_RS20370	COG0488	(ABC) transporter
K6V27_RS20385	COG0745	RESPONSE REGULATOR receiver
K6V27_RS20390	COG5002	protein histidine kinase activity
K6V27_RS20435	COG3033	Beta-eliminating lyase
K6V27_RS20460	COG0629	single-stranded DNA binding
K6V27_RS20465	COG1194	a g-specific adenine glycosylase
K6V27_RS20475	COG1530	ribonuclease E activity
K6V27_RS20480	COG2885	chlorophyll binding
K6V27_RS20500	COG2885	chlorophyll binding
K6V27_RS20550	COG0305	Participates in initiation and elongation during chromosome replication
K6V27_RS20565	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS20585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K6V27_RS20595	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K6V27_RS20610	COG4191	Histidine kinase
K6V27_RS20615	COG2204	response regulator
K6V27_RS20625	COG5002	protein histidine kinase activity
K6V27_RS20625	COG2205	protein histidine kinase activity
K6V27_RS20625	COG0784	Response regulator, receiver
K6V27_RS20645	COG1136	(ABC) transporter
K6V27_RS20655	COG1252	NADH dehydrogenase
K6V27_RS20660	COG1705	Flagellar rod assembly protein muramidase FlgJ
K6V27_RS20675	COG3059	membrane
K6V27_RS20680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K6V27_RS20685	COG0488	(ABC) transporter
K6V27_RS20710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K6V27_RS20720	COG0739	heme binding
K6V27_RS20725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K6V27_RS20730	COG1629	transport
K6V27_RS20730	COG4206	TonB-dependent receptor
K6V27_RS20740	COG0686	Belongs to the AlaDH PNT family
K6V27_RS20780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K6V27_RS20790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K6V27_RS20800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K6V27_RS20830	COG1595	DNA-templated transcription, initiation
K6V27_RS20845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K6V27_RS20850	COG1741	Belongs to the pirin family
K6V27_RS20855	COG0259	pyridoxamine-phosphate oxidase activity
K6V27_RS20915	COG0456	acetyltransferase
K6V27_RS20950	COG1918	ferrous iron import across plasma membrane
K6V27_RS20950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
K6V27_RS20955	COG0037	tRNA processing
K6V27_RS20970	COG3119	arylsulfatase activity
K6V27_RS20975	COG2202	Pas domain
K6V27_RS20975	COG2205	protein histidine kinase activity
K6V27_RS20980	COG2202	Pas domain
K6V27_RS20980	COG2205	protein histidine kinase activity
K6V27_RS20985	COG0534	Mate efflux family protein
K6V27_RS20990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K6V27_RS21010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K6V27_RS21015	COG1858	cytochrome C peroxidase
K6V27_RS21020	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K6V27_RS21035	COG1983	PspC domain protein
K6V27_RS21040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K6V27_RS21065	COG2195	Cleaves the N-terminal amino acid of tripeptides
K6V27_RS21085	COG1629	transport
K6V27_RS21085	COG4206	TonB-dependent receptor
K6V27_RS21100	COG3119	arylsulfatase activity
K6V27_RS21105	COG0668	transmembrane transport
K6V27_RS21110	COG3119	arylsulfatase activity
K6V27_RS21120	COG3250	beta-galactosidase activity
K6V27_RS21125	COG3525	Glycosyl hydrolase, family 20, catalytic domain
K6V27_RS21130	COG3119	arylsulfatase activity
K6V27_RS21140	COG0702	epimerase
K6V27_RS21145	COG4206	TonB-dependent receptor
K6V27_RS21145	COG1629	transport
K6V27_RS21155	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K6V27_RS21160	COG1660	Displays ATPase and GTPase activities
K6V27_RS21165	COG0745	RESPONSE REGULATOR receiver
K6V27_RS21165	COG2205	protein histidine kinase activity
K6V27_RS21165	COG0745	RESPONSE REGULATOR receiver
K6V27_RS21165	COG2205	protein histidine kinase activity
K6V27_RS21165	COG3292	Two component regulator propeller
K6V27_RS21165	COG3292	Two component regulator propeller
K6V27_RS21170	COG3119	arylsulfatase activity
K6V27_RS21220	COG1216	Glycosyl transferase, family 2
K6V27_RS21225	COG1216	Glycosyl transferase, family 2
K6V27_RS21235	COG1442	glycosyl transferase family 8
K6V27_RS21235	COG1216	Glycosyl transferase, family 2
K6V27_RS21245	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K6V27_RS21255	COG2244	polysaccharide biosynthetic process
K6V27_RS21285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K6V27_RS21290	COG1830	Aldolase
K6V27_RS21295	COG0588	phosphoglycerate mutase activity
K6V27_RS21300	COG0784	Response regulator, receiver
K6V27_RS21300	COG2205	protein histidine kinase activity
K6V27_RS21305	COG1119	ATPase activity
K6V27_RS21310	COG1523	belongs to the glycosyl hydrolase 13 family
K6V27_RS21315	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K6V27_RS21425	COG2433	Pfam Transposase IS66
K6V27_RS21500	COG0560	Phosphoserine phosphatase
K6V27_RS21505	COG4974	Belongs to the 'phage' integrase family
K6V27_RS21540	COG0551	DNA topoisomerase type I activity
K6V27_RS21540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K6V27_RS21560	COG2205	protein histidine kinase activity
K6V27_RS21560	COG2198	Histidine kinase
K6V27_RS21560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K6V27_RS21560	COG0784	Response regulator, receiver
K6V27_RS21595	COG3344	reverse transcriptase
K6V27_RS21700	COG4974	Belongs to the 'phage' integrase family
K6V27_RS21780	COG4974	Belongs to the 'phage' integrase family
K6V27_RS21790	COG4974	Belongs to the 'phage' integrase family
K6V27_RS21850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K6V27_RS21855	COG2814	Major facilitator Superfamily
K6V27_RS21860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K6V27_RS21865	COG0126	phosphoglycerate kinase activity
K6V27_RS21885	COG0424	maF-like protein
K6V27_RS21905	COG0778	Nitroreductase
K6V27_RS21915	COG0288	reversible hydration of carbon dioxide
K6V27_RS21925	COG4771	TonB-dependent receptor
K6V27_RS21940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6V27_RS21950	COG0511	ligase activity, forming carbon-carbon bonds
K6V27_RS21955	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K6V27_RS21965	COG0191	fructose-bisphosphate aldolase activity
K6V27_RS21970	COG0254	rRNA binding
K6V27_RS21975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS21980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K6V27_RS22055	COG1216	Glycosyl transferase, family 2
K6V27_RS22075	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K6V27_RS22085	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
K6V27_RS22090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
K6V27_RS22115	COG4750	Nucleotidyl transferase
K6V27_RS22155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K6V27_RS22170	COG1280	lysine exporter protein (LysE YggA)
K6V27_RS22180	COG3292	Two component regulator propeller
K6V27_RS22180	COG0745	RESPONSE REGULATOR receiver
K6V27_RS22180	COG3292	Two component regulator propeller
K6V27_RS22180	COG2205	protein histidine kinase activity
K6V27_RS22180	COG0745	RESPONSE REGULATOR receiver
K6V27_RS22180	COG2205	protein histidine kinase activity
K6V27_RS22195	COG1649	PFAM Uncharacterised BCR, COG1649
K6V27_RS22220	COG1966	Carbon starvation protein
K6V27_RS22230	COG1649	PFAM Uncharacterised BCR, COG1649
K6V27_RS22265	COG2113	Glycine betaine
K6V27_RS22270	COG4176	ABC-type proline glycine betaine transport system permease component
K6V27_RS22290	COG3292	Two component regulator propeller
K6V27_RS22290	COG0745	RESPONSE REGULATOR receiver
K6V27_RS22290	COG2205	protein histidine kinase activity
K6V27_RS22305	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K6V27_RS22305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K6V27_RS22315	COG1621	beta-fructofuranosidase activity
K6V27_RS22330	COG0561	phosphatase activity
K6V27_RS22335	COG1629	transport
K6V27_RS22335	COG4206	TonB-dependent receptor
K6V27_RS22345	COG1621	beta-fructofuranosidase activity
K6V27_RS22360	COG3250	beta-galactosidase activity
K6V27_RS22365	COG3537	Alpha-1,2-mannosidase
K6V27_RS22395	COG1629	transport
K6V27_RS22405	COG3250	beta-galactosidase activity
K6V27_RS22415	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS22425	COG1472	Belongs to the glycosyl hydrolase 3 family
K6V27_RS22435	COG1752	Esterase of the alpha-beta hydrolase superfamily
K6V27_RS22440	COG0475	glutathione-regulated potassium exporter activity
K6V27_RS22480	COG2885	chlorophyll binding
K6V27_RS22495	COG3279	Response regulator of the LytR AlgR family
K6V27_RS22530	COG2205	protein histidine kinase activity
K6V27_RS22535	COG2205	protein histidine kinase activity
K6V27_RS22550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K6V27_RS22555	COG1960	acyl-CoA dehydrogenase activity
K6V27_RS22575	COG1956	GAF domain-containing protein
K6V27_RS22585	COG0484	heat shock protein binding
K6V27_RS22590	COG2194	sulfuric ester hydrolase activity
K6V27_RS22625	COG0028	Belongs to the TPP enzyme family
K6V27_RS22645	COG2885	chlorophyll binding
K6V27_RS22665	COG0459	protein refolding
K6V27_RS22670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K6V27_RS22685	COG5002	protein histidine kinase activity
K6V27_RS22685	COG2205	protein histidine kinase activity
K6V27_RS22685	COG0784	Response regulator, receiver
K6V27_RS22700	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K6V27_RS22710	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K6V27_RS22715	COG0823	Involved in the tonB-independent uptake of proteins
K6V27_RS22715	COG1506	peptidase
K6V27_RS22725	COG0124	histidyl-tRNA synthetase
K6V27_RS22740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K6V27_RS22765	COG0514	ATP-dependent DNA helicase (RecQ)
K6V27_RS22780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K6V27_RS22790	COG0671	phosphoesterase, PA-phosphatase related
K6V27_RS22805	COG0473	3-isopropylmalate dehydrogenase activity
K6V27_RS22815	COG0066	3-isopropylmalate dehydratase activity
K6V27_RS22820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K6V27_RS22825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K6V27_RS22870	COG4948	Mandelate Racemase Muconate Lactonizing
K6V27_RS22880	COG3507	Belongs to the glycosyl hydrolase 43 family
K6V27_RS22885	COG0702	epimerase
K6V27_RS22890	COG4771	TonB-dependent receptor
K6V27_RS22910	COG0616	signal peptide processing
K6V27_RS22915	COG1663	tetraacyldisaccharide 4'-kinase activity
K6V27_RS22920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K6V27_RS22925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K6V27_RS22945	COG0513	Belongs to the DEAD box helicase family
K6V27_RS22950	COG2070	2-Nitropropane dioxygenase
K6V27_RS22955	COG0724	RNA recognition motif
K6V27_RS22970	COG3973	AAA domain
K6V27_RS22990	COG1704	LemA family
K6V27_RS23005	COG0534	Mate efflux family protein
K6V27_RS23015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K6V27_RS23025	COG1917	Cupin 2, conserved barrel domain protein
K6V27_RS23025	COG4977	sequence-specific DNA binding
K6V27_RS23055	COG1028	Short-chain dehydrogenase reductase Sdr
K6V27_RS23060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K6V27_RS23070	COG0439	Biotin carboxylase
K6V27_RS23075	COG0511	ligase activity, forming carbon-carbon bonds
K6V27_RS23075	COG5016	pyruvate
K6V27_RS23080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K6V27_RS23090	COG2855	membrane
K6V27_RS23095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K6V27_RS23135	COG0210	DNA helicase
K6V27_RS23145	COG2873	o-acetylhomoserine
K6V27_RS23175	COG4974	Belongs to the 'phage' integrase family
K6V27_RS23180	COG4974	Belongs to the 'phage' integrase family
K6V27_RS23265	COG1192	Involved in chromosome partitioning
K6V27_RS23295	COG1120	ATPase activity
K6V27_RS23300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6V27_RS23360	COG1538	Outer membrane efflux protein
K6V27_RS23390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K6V27_RS23410	COG0024	Methionine aminopeptidase
K6V27_RS23415	COG0617	tRNA 3'-terminal CCA addition
K6V27_RS23435	COG0632	four-way junction helicase activity
K6V27_RS23440	COG0673	inositol 2-dehydrogenase activity
K6V27_RS23455	COG1272	protein, Hemolysin III
K6V27_RS23470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K6V27_RS23495	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS23525	COG1328	CTP reductase activity
K6V27_RS23535	COG2814	Major facilitator Superfamily
K6V27_RS23540	COG0750	zinc metalloprotease
K6V27_RS23545	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K6V27_RS23555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K6V27_RS23560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K6V27_RS23580	COG0194	GDP metabolic process
K6V27_RS23590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K6V27_RS23600	COG1408	metallophosphoesterase
K6V27_RS23605	COG1575	Belongs to the MenA family. Type 1 subfamily
K6V27_RS23610	COG1088	dTDP-glucose 4,6-dehydratase activity
K6V27_RS23615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
K6V27_RS23625	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K6V27_RS23645	COG2205	protein histidine kinase activity
K6V27_RS23675	COG3023	N-Acetylmuramoyl-L-alanine amidase
K6V27_RS23690	COG4771	TonB-dependent receptor
K6V27_RS23705	COG2205	protein histidine kinase activity
K6V27_RS23705	COG0784	Response regulator, receiver
K6V27_RS23710	COG0488	(ABC) transporter
K6V27_RS23760	COG1595	DNA-templated transcription, initiation
K6V27_RS23775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K6V27_RS23785	COG1522	sequence-specific DNA binding
K6V27_RS23815	COG0811	peptide transport
K6V27_RS23825	COG0084	hydrolase, TatD family'
K6V27_RS23845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K6V27_RS23850	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K6V27_RS23855	COG0205	6-phosphofructokinase activity
K6V27_RS23900	COG0372	Belongs to the citrate synthase family
K6V27_RS23905	COG0538	isocitrate dehydrogenase activity
K6V27_RS23915	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K6V27_RS23920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K6V27_RS23935	COG0028	Belongs to the TPP enzyme family
K6V27_RS23940	COG0129	dihydroxy-acid dehydratase activity
K6V27_RS23945	COG1047	Peptidyl-prolyl cis-trans
K6V27_RS23950	COG3681	Belongs to the UPF0597 family
K6V27_RS23970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K6V27_RS23995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K6V27_RS23995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K6V27_RS24000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
K6V27_RS24005	COG0569	domain protein
K6V27_RS24005	COG2985	domain, Protein
K6V27_RS24040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K6V27_RS24045	COG1120	ATPase activity
K6V27_RS24060	COG2188	Transcriptional regulator
K6V27_RS24080	COG4206	TonB-dependent receptor
K6V27_RS24080	COG1629	transport
K6V27_RS24140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K6V27_RS24145	COG1609	Transcriptional regulator
K6V27_RS24145	COG2207	Transcriptional regulator
K6V27_RS24155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K6V27_RS24160	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K6V27_RS24165	COG0166	Belongs to the GPI family
K6V27_RS24195	COG2502	aspartate--ammonia ligase
K6V27_RS24200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K6V27_RS24225	COG3876	Protein conserved in bacteria
K6V27_RS24250	COG3340	Belongs to the peptidase S51 family
K6V27_RS24255	COG2378	regulation of single-species biofilm formation
K6V27_RS24290	COG0358	DNA primase activity
K6V27_RS24315	COG4974	Belongs to the 'phage' integrase family
K6V27_RS24320	COG4974	Belongs to the 'phage' integrase family
K6V27_RS24380	COG4771	TonB-dependent receptor
K6V27_RS24395	COG2885	chlorophyll binding
K6V27_RS24440	COG0860	N-Acetylmuramoyl-L-alanine amidase