locus-tag	class	description
INE82_RS00020	COG4771	TonB-dependent receptor
INE82_RS00025	COG0702	epimerase
INE82_RS00060	COG3250	beta-galactosidase activity
INE82_RS00075	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS00090	COG1629	transport
INE82_RS00095	COG0561	phosphatase activity
INE82_RS00130	COG3537	Alpha-1,2-mannosidase
INE82_RS00145	COG3537	Alpha-1,2-mannosidase
INE82_RS00155	COG2017	converts alpha-aldose to the beta-anomer
INE82_RS00180	COG1373	ATPase (AAA superfamily
INE82_RS00185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INE82_RS00190	COG1022	Amp-dependent synthetase and ligase
INE82_RS00195	COG0612	Peptidase, M16
INE82_RS00210	COG2954	triphosphatase activity
INE82_RS00270	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS00280	COG4771	TonB-dependent receptor
INE82_RS00335	COG0673	inositol 2-dehydrogenase activity
INE82_RS00345	COG0673	inositol 2-dehydrogenase activity
INE82_RS00370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INE82_RS00380	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS00395	COG0561	phosphatase activity
INE82_RS00400	COG4771	TonB-dependent receptor
INE82_RS00415	COG1609	Transcriptional regulator
INE82_RS00415	COG2207	Transcriptional regulator
INE82_RS00420	COG0423	glycine-tRNA ligase activity
INE82_RS00430	COG1609	Transcriptional regulator
INE82_RS00445	COG0738	Major facilitator superfamily
INE82_RS00450	COG1063	alcohol dehydrogenase
INE82_RS00465	COG2211	Major facilitator Superfamily
INE82_RS00470	COG2247	cell wall binding repeat
INE82_RS00470	COG2385	sporulation resulting in formation of a cellular spore
INE82_RS00475	COG1215	transferase activity, transferring glycosyl groups
INE82_RS00480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE82_RS00535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INE82_RS00545	COG0589	response to stress
INE82_RS00545	COG0475	glutathione-regulated potassium exporter activity
INE82_RS00550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
INE82_RS00555	COG1136	(ABC) transporter
INE82_RS00565	COG0733	neurotransmitter:sodium symporter activity
INE82_RS00575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INE82_RS00580	COG0784	Response regulator, receiver
INE82_RS00580	COG5002	protein histidine kinase activity
INE82_RS00585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
INE82_RS00590	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
INE82_RS00595	COG0312	modulator of DNA gyrase
INE82_RS00600	COG0312	modulator of DNA gyrase
INE82_RS00605	COG1704	LemA family
INE82_RS00635	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS00645	COG1501	Belongs to the glycosyl hydrolase 31 family
INE82_RS00655	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS00680	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS00685	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS00715	COG3292	Two component regulator propeller
INE82_RS00715	COG0745	RESPONSE REGULATOR receiver
INE82_RS00715	COG2205	protein histidine kinase activity
INE82_RS00725	COG4771	TonB-dependent receptor
INE82_RS00770	COG1346	cytolysis
INE82_RS00775	COG1380	Effector of murein hydrolase LrgA
INE82_RS00780	COG0280	phosphate acetyltransferase
INE82_RS00785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
INE82_RS00790	COG0463	Glycosyl transferase, family 2
INE82_RS00790	COG1216	Glycosyl transferase, family 2
INE82_RS00795	COG2003	Belongs to the UPF0758 family
INE82_RS00805	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE82_RS00810	COG0366	Alpha amylase catalytic
INE82_RS00825	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE82_RS00830	COG4206	TonB-dependent receptor
INE82_RS00830	COG1629	transport
INE82_RS00835	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS00840	COG0366	Alpha amylase catalytic
INE82_RS00850	COG1785	Belongs to the alkaline phosphatase family
INE82_RS00855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
INE82_RS00860	COG0230	Belongs to the bacterial ribosomal protein bL34 family
INE82_RS00865	COG0515	serine threonine protein kinase
INE82_RS00865	COG2815	serine threonine protein kinase
INE82_RS00870	COG0564	pseudouridine synthase activity
INE82_RS00875	COG1181	Belongs to the D-alanine--D-alanine ligase family
INE82_RS00895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INE82_RS00900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
INE82_RS00905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
INE82_RS00910	COG0436	Aminotransferase
INE82_RS00920	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
INE82_RS00935	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INE82_RS00940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
INE82_RS00950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INE82_RS00950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INE82_RS00955	COG2890	protein-(glutamine-N5) methyltransferase activity
INE82_RS00965	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
INE82_RS00975	COG0165	Argininosuccinate lyase
INE82_RS00990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INE82_RS01010	COG3292	Two component regulator propeller
INE82_RS01010	COG2205	protein histidine kinase activity
INE82_RS01010	COG3292	Two component regulator propeller
INE82_RS01010	COG0745	RESPONSE REGULATOR receiver
INE82_RS01010	COG2205	protein histidine kinase activity
INE82_RS01010	COG0745	RESPONSE REGULATOR receiver
INE82_RS01015	COG0471	metal ion transport
INE82_RS01070	COG4771	TonB-dependent receptor
INE82_RS01090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
INE82_RS01095	COG1396	sequence-specific DNA binding
INE82_RS01095	COG1917	Cupin 2, conserved barrel domain protein
INE82_RS01100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INE82_RS01105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
INE82_RS01110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
INE82_RS01115	COG0137	argininosuccinate synthase activity
INE82_RS01125	COG1438	arginine binding
INE82_RS01130	COG1070	Carbohydrate kinase
INE82_RS01135	COG4806	L-rhamnose isomerase
INE82_RS01145	COG0235	Class ii aldolase
INE82_RS01150	COG1454	alcohol dehydrogenase
INE82_RS01180	COG0564	pseudouridine synthase activity
INE82_RS01215	COG3537	Alpha-1,2-mannosidase
INE82_RS01220	COG3292	Two component regulator propeller
INE82_RS01220	COG2205	protein histidine kinase activity
INE82_RS01220	COG0745	RESPONSE REGULATOR receiver
INE82_RS01230	COG4206	TonB-dependent receptor
INE82_RS01230	COG1629	transport
INE82_RS01235	COG0702	epimerase
INE82_RS01270	COG3119	arylsulfatase activity
INE82_RS01285	COG3119	arylsulfatase activity
INE82_RS01290	COG3292	Two component regulator propeller
INE82_RS01290	COG0745	RESPONSE REGULATOR receiver
INE82_RS01290	COG2205	protein histidine kinase activity
INE82_RS01295	COG2204	response regulator
INE82_RS01300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INE82_RS01305	COG0612	Peptidase, M16
INE82_RS01310	COG0534	Mate efflux family protein
INE82_RS01315	COG2205	protein histidine kinase activity
INE82_RS01315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE82_RS01360	COG0488	(ABC) transporter
INE82_RS01365	COG3590	peptidase
INE82_RS01370	COG0138	bifunctional purine biosynthesis protein purh
INE82_RS01395	COG0772	Belongs to the SEDS family
INE82_RS01405	COG1774	PSP1 C-terminal conserved region
INE82_RS01410	COG0470	DNA polymerase III
INE82_RS01415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
INE82_RS01425	COG2193	ferroxidase activity
INE82_RS01430	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE82_RS01430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INE82_RS01495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INE82_RS01500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
INE82_RS01505	COG1160	GTP binding
INE82_RS01515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
INE82_RS01520	COG1127	ABC transporter
INE82_RS01525	COG0724	RNA recognition motif
INE82_RS01530	COG0544	peptidyl-prolyl cis-trans isomerase activity
INE82_RS01535	COG0740	serine-type endopeptidase activity
INE82_RS01540	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
INE82_RS01545	COG0514	ATP-dependent DNA helicase (RecQ)
INE82_RS01550	COG0516	GMP reductase activity
INE82_RS01550	COG0517	IMP dehydrogenase activity
INE82_RS01555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INE82_RS01565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INE82_RS01580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
INE82_RS01595	COG4771	TonB-dependent receptor
INE82_RS01615	COG3537	Alpha-1,2-mannosidase
INE82_RS01650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
INE82_RS01660	COG3022	response to hydroperoxide
INE82_RS01665	COG0110	maltose O-acetyltransferase activity
INE82_RS01685	COG1187	pseudouridine synthase activity
INE82_RS01690	COG0017	Asparaginyl-tRNA synthetase
INE82_RS01700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
INE82_RS01705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
INE82_RS01710	COG0052	Belongs to the universal ribosomal protein uS2 family
INE82_RS01715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
INE82_RS01730	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
INE82_RS01735	COG0179	Fumarylacetoacetate (FAA) hydrolase
INE82_RS01740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
INE82_RS01755	COG0482	sulfurtransferase activity
INE82_RS01765	COG1570	exodeoxyribonuclease VII activity
INE82_RS01775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INE82_RS01785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
INE82_RS01790	COG0489	protein tyrosine kinase activity
INE82_RS01795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE82_RS01830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS01850	COG0714	Associated with various cellular activities
INE82_RS01855	COG2425	protein containing a von Willebrand factor type A (vWA) domain
INE82_RS01860	COG3552	Protein containing von Willebrand factor type A (VWA) domain
INE82_RS01865	COG0039	L-malate dehydrogenase activity
INE82_RS01885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
INE82_RS01890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
INE82_RS01895	COG0811	peptide transport
INE82_RS01900	COG0848	biopolymer transport protein
INE82_RS01915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
INE82_RS01920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INE82_RS01925	COG0105	UTP biosynthetic process
INE82_RS01930	COG0739	heme binding
INE82_RS01945	COG0149	triose-phosphate isomerase activity
INE82_RS01955	COG0302	gtp cyclohydrolase
INE82_RS01960	COG0358	DNA primase activity
INE82_RS01970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
INE82_RS01975	COG0436	Aminotransferase
INE82_RS01990	COG0514	ATP-dependent DNA helicase (RecQ)
INE82_RS01995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INE82_RS01995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
INE82_RS02010	COG0009	L-threonylcarbamoyladenylate synthase
INE82_RS02020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
INE82_RS02025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
INE82_RS02030	COG2333	competence protein COMEC
INE82_RS02030	COG0658	competence protein
INE82_RS02035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
INE82_RS02045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INE82_RS02055	COG4771	TonB-dependent receptor
INE82_RS02060	COG0561	phosphatase activity
INE82_RS02080	COG0745	RESPONSE REGULATOR receiver
INE82_RS02080	COG2205	protein histidine kinase activity
INE82_RS02080	COG3292	Two component regulator propeller
INE82_RS02085	COG4771	TonB-dependent receptor
INE82_RS02105	COG3537	Alpha-1,2-mannosidase
INE82_RS02110	COG3537	Alpha-1,2-mannosidase
INE82_RS02120	COG3537	Alpha-1,2-mannosidase
INE82_RS02125	COG3279	Response regulator of the LytR AlgR family
INE82_RS02130	COG3275	phosphorelay sensor kinase activity
INE82_RS02135	COG1566	PFAM secretion protein HlyD family protein
INE82_RS02150	COG0386	Belongs to the glutathione peroxidase family
INE82_RS02155	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
INE82_RS02160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INE82_RS02175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
INE82_RS02190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INE82_RS02195	COG0742	ribosomal rna small subunit methyltransferase
INE82_RS02210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INE82_RS02215	COG4771	TonB-dependent receptor
INE82_RS02250	COG3537	Alpha-1,2-mannosidase
INE82_RS02255	COG3537	Alpha-1,2-mannosidase
INE82_RS02275	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
INE82_RS02280	COG0739	heme binding
INE82_RS02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INE82_RS02295	COG0741	lytic transglycosylase activity
INE82_RS02295	COG1388	LysM domain
INE82_RS02305	COG1475	DNA binding
INE82_RS02310	COG1192	Involved in chromosome partitioning
INE82_RS02315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
INE82_RS02320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE82_RS02330	COG4589	Belongs to the CDS family
INE82_RS02335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INE82_RS02340	COG0799	negative regulation of ribosome biogenesis
INE82_RS02350	COG0702	epimerase
INE82_RS02355	COG1629	transport
INE82_RS02355	COG4206	TonB-dependent receptor
INE82_RS02360	COG3291	Pkd domain containing protein
INE82_RS02360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS02365	COG1196	nuclear chromosome segregation
INE82_RS02370	COG2239	Acts as a magnesium transporter
INE82_RS02375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
INE82_RS02385	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE82_RS02420	COG1119	ATPase activity
INE82_RS02430	COG0668	transmembrane transport
INE82_RS02435	COG0662	Cupin 2, conserved barrel domain protein
INE82_RS02435	COG2207	Transcriptional regulator
INE82_RS02460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE82_RS02465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INE82_RS02470	COG0713	ATP synthesis coupled electron transport
INE82_RS02485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
INE82_RS02490	COG0649	NAD binding
INE82_RS02490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE82_RS02495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE82_RS02500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE82_RS02535	COG3250	beta-galactosidase activity
INE82_RS02545	COG3250	beta-galactosidase activity
INE82_RS02555	COG0657	acetylesterase activity
INE82_RS02555	COG2755	lipolytic protein G-D-S-L family
INE82_RS02570	COG4771	TonB-dependent receptor
INE82_RS02575	COG0702	epimerase
INE82_RS02590	COG0702	epimerase
INE82_RS02605	COG4771	TonB-dependent receptor
INE82_RS02610	COG0702	epimerase
INE82_RS02615	COG4206	TonB-dependent receptor
INE82_RS02615	COG1629	transport
INE82_RS02630	COG3537	Alpha-1,2-mannosidase
INE82_RS02650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INE82_RS02655	COG0569	domain protein
INE82_RS02660	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INE82_RS02670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INE82_RS02675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
INE82_RS02680	COG0805	protein transport
INE82_RS02690	COG2271	Major facilitator Superfamily
INE82_RS02695	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
INE82_RS02700	COG3775	system Galactitol-specific IIC component
INE82_RS02715	COG2755	lipolytic protein G-D-S-L family
INE82_RS02720	COG0745	RESPONSE REGULATOR receiver
INE82_RS02720	COG3292	Two component regulator propeller
INE82_RS02720	COG2205	protein histidine kinase activity
INE82_RS02730	COG0702	epimerase
INE82_RS02735	COG1629	transport
INE82_RS02755	COG3279	Response regulator of the LytR AlgR family
INE82_RS02770	COG4206	TonB-dependent receptor
INE82_RS02770	COG1629	transport
INE82_RS02785	COG3292	Two component regulator propeller
INE82_RS02785	COG0745	RESPONSE REGULATOR receiver
INE82_RS02785	COG2205	protein histidine kinase activity
INE82_RS02790	COG1242	4 iron, 4 sulfur cluster binding
INE82_RS02800	COG0363	glucosamine-6-phosphate deaminase activity
INE82_RS02805	COG0009	L-threonylcarbamoyladenylate synthase
INE82_RS02815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INE82_RS02820	COG0561	phosphatase activity
INE82_RS02825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
INE82_RS02830	COG1408	metallophosphoesterase
INE82_RS02855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INE82_RS02880	COG2755	lipolytic protein G-D-S-L family
INE82_RS02910	COG3401	FG-GAP repeat protein
INE82_RS02915	COG3250	beta-galactosidase activity
INE82_RS02925	COG3250	beta-galactosidase activity
INE82_RS02935	COG3345	alpha-galactosidase
INE82_RS02950	COG3250	beta-galactosidase activity
INE82_RS03015	COG4771	TonB-dependent receptor
INE82_RS03030	COG0702	epimerase
INE82_RS03035	COG4771	TonB-dependent receptor
INE82_RS03055	COG4771	TonB-dependent receptor
INE82_RS03060	COG0702	epimerase
INE82_RS03075	COG4771	TonB-dependent receptor
INE82_RS03100	COG2755	lipolytic protein G-D-S-L family
INE82_RS03110	COG3401	FG-GAP repeat protein
INE82_RS03120	COG3254	rhamnose metabolic process
INE82_RS03125	COG3292	Two component regulator propeller
INE82_RS03125	COG2205	protein histidine kinase activity
INE82_RS03125	COG0745	RESPONSE REGULATOR receiver
INE82_RS03125	COG2205	protein histidine kinase activity
INE82_RS03125	COG3292	Two component regulator propeller
INE82_RS03125	COG0745	RESPONSE REGULATOR receiver
INE82_RS03140	COG3250	beta-galactosidase activity
INE82_RS03145	COG0745	RESPONSE REGULATOR receiver
INE82_RS03145	COG2205	protein histidine kinase activity
INE82_RS03145	COG3292	Two component regulator propeller
INE82_RS03155	COG0546	phosphoglycolate phosphatase activity
INE82_RS03175	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
INE82_RS03185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INE82_RS03195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
INE82_RS03200	COG1506	peptidase
INE82_RS03200	COG0823	Involved in the tonB-independent uptake of proteins
INE82_RS03220	COG5433	transposase activity
INE82_RS03250	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
INE82_RS03265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INE82_RS03265	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
INE82_RS03270	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE82_RS03275	COG1078	dGTPase activity
INE82_RS03280	COG0284	orotidine-5'-phosphate decarboxylase activity
INE82_RS03285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
INE82_RS03295	COG1704	LemA family
INE82_RS03310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
INE82_RS03315	COG2226	methyltransferase
INE82_RS03320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
INE82_RS03325	COG1702	phosphate starvation-inducible protein PhoH
INE82_RS03340	COG2268	Band 7 protein
INE82_RS03430	COG0745	RESPONSE REGULATOR receiver
INE82_RS03430	COG2205	protein histidine kinase activity
INE82_RS03430	COG3292	Two component regulator propeller
INE82_RS03435	COG0101	tRNA pseudouridine synthase activity
INE82_RS03455	COG3250	beta-galactosidase activity
INE82_RS03460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INE82_RS03465	COG0673	inositol 2-dehydrogenase activity
INE82_RS03485	COG4771	TonB-dependent receptor
INE82_RS03505	COG5434	Belongs to the glycosyl hydrolase 28 family
INE82_RS03510	COG0673	inositol 2-dehydrogenase activity
INE82_RS03525	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
INE82_RS03535	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
INE82_RS03545	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
INE82_RS03550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INE82_RS03555	COG0793	Belongs to the peptidase S41A family
INE82_RS03560	COG2131	deaminase
INE82_RS03570	COG0339	signal peptide processing
INE82_RS03580	COG1970	mechanosensitive ion channel activity
INE82_RS03585	COG0519	Catalyzes the synthesis of GMP from XMP
INE82_RS03585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
INE82_RS03600	COG0438	transferase activity, transferring glycosyl groups
INE82_RS03605	COG1216	Glycosyl transferase, family 2
INE82_RS03665	COG4771	TonB-dependent receptor
INE82_RS03700	COG0438	transferase activity, transferring glycosyl groups
INE82_RS03715	COG0297	glycogen (starch) synthase activity
INE82_RS03720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
INE82_RS03725	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
INE82_RS03730	COG0543	2 iron, 2 sulfur cluster binding
INE82_RS03740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
INE82_RS03745	COG0211	Belongs to the bacterial ribosomal protein bL27 family
INE82_RS03750	COG0261	This protein binds to 23S rRNA in the presence of protein L20
INE82_RS03765	COG0791	NLP P60 protein
INE82_RS03780	COG0612	Peptidase, M16
INE82_RS03785	COG0612	Peptidase, M16
INE82_RS03790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
INE82_RS03795	COG1597	lipid kinase activity
INE82_RS03800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
INE82_RS03815	COG1136	(ABC) transporter
INE82_RS03835	COG2211	Major facilitator Superfamily
INE82_RS03840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INE82_RS03855	COG1674	ftsk spoiiie
INE82_RS03865	COG0492	ferredoxin-NADP+ reductase activity
INE82_RS03870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS03900	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE82_RS03900	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE82_RS03910	COG1234	tRNA 3'-trailer cleavage
INE82_RS03930	COG3956	TIGRFAM MazG family protein
INE82_RS03945	COG0525	valine-tRNA ligase activity
INE82_RS03950	COG0784	Response regulator, receiver
INE82_RS03950	COG2205	protein histidine kinase activity
INE82_RS03965	COG4206	TonB-dependent receptor
INE82_RS03965	COG1629	transport
INE82_RS03990	COG0653	protein targeting
INE82_RS03995	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
INE82_RS04005	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
INE82_RS04025	COG1253	flavin adenine dinucleotide binding
INE82_RS04035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
INE82_RS04045	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
INE82_RS04050	COG2204	response regulator
INE82_RS04090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
INE82_RS04090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
INE82_RS04110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
INE82_RS04115	COG0563	adenylate kinase activity
INE82_RS04120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INE82_RS04125	COG1496	oxidoreductase activity
INE82_RS04140	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS04145	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS04155	COG0477	Major facilitator Superfamily
INE82_RS04155	COG2814	Major facilitator Superfamily
INE82_RS04160	COG0457	Tetratricopeptide repeat
INE82_RS04165	COG2706	6-phosphogluconolactonase activity
INE82_RS04190	COG1629	transport
INE82_RS04190	COG4206	TonB-dependent receptor
INE82_RS04255	COG3142	Participates in the control of copper homeostasis
INE82_RS04260	COG1418	mRNA catabolic process
INE82_RS04290	COG1070	Carbohydrate kinase
INE82_RS04295	COG1063	alcohol dehydrogenase
INE82_RS04300	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
INE82_RS04330	COG1333	cytochrome c biogenesis protein
INE82_RS04330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INE82_RS04370	COG0673	inositol 2-dehydrogenase activity
INE82_RS04380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INE82_RS04385	COG2832	Protein of unknown function (DUF454)
INE82_RS04395	COG0602	queuosine metabolic process
INE82_RS04400	COG0247	lactate metabolic process
INE82_RS04405	COG1139	Iron-sulfur cluster binding protein
INE82_RS04415	COG0351	phosphomethylpyrimidine kinase
INE82_RS04440	COG4589	Belongs to the CDS family
INE82_RS04450	COG2304	oxidoreductase activity
INE82_RS04460	COG1393	Belongs to the ArsC family
INE82_RS04470	COG4206	TonB-dependent receptor
INE82_RS04470	COG1629	transport
INE82_RS04485	COG2233	PERMEase
INE82_RS04490	COG1509	lysine 2,3-aminomutase activity
INE82_RS04500	COG1115	amino acid carrier protein
INE82_RS04540	COG1285	pathogenesis
INE82_RS04550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INE82_RS04555	COG0741	lytic transglycosylase activity
INE82_RS04555	COG1388	LysM domain
INE82_RS04585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INE82_RS04600	COG0534	Mate efflux family protein
INE82_RS04610	COG0564	pseudouridine synthase activity
INE82_RS04635	COG0346	lactoylglutathione lyase activity
INE82_RS04650	COG0662	Cupin 2, conserved barrel domain protein
INE82_RS04650	COG2207	Transcriptional regulator
INE82_RS04655	COG0653	protein targeting
INE82_RS04725	COG1111	helicase
INE82_RS04725	COG1205	dead DEAH box helicase
INE82_RS04725	COG1205	dead DEAH box helicase
INE82_RS04725	COG1111	helicase
INE82_RS04865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
INE82_RS04875	COG2910	NAD(P)H-binding
INE82_RS04885	COG4864	UPF0365 protein
INE82_RS04900	COG0037	tRNA processing
INE82_RS04910	COG1477	protein flavinylation
INE82_RS04915	COG1971	Probably functions as a manganese efflux pump
INE82_RS04930	COG0463	Glycosyl transferase, family 2
INE82_RS04955	COG1595	DNA-templated transcription, initiation
INE82_RS04960	COG0148	phosphopyruvate hydratase activity
INE82_RS04970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
INE82_RS04985	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS04990	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
INE82_RS04995	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE82_RS05000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
INE82_RS05005	COG4651	solute:proton antiporter activity
INE82_RS05005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INE82_RS05015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INE82_RS05020	COG0193	aminoacyl-tRNA hydrolase activity
INE82_RS05025	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
INE82_RS05035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INE82_RS05040	COG1862	Preprotein translocase
INE82_RS05050	COG0237	dephospho-CoA kinase activity
INE82_RS05065	COG0542	response to heat
INE82_RS05075	COG0583	DNA-binding transcription factor activity
INE82_RS05085	COG2855	membrane
INE82_RS05090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
INE82_RS05095	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
INE82_RS05115	COG0443	Heat shock 70 kDa protein
INE82_RS05120	COG0306	phosphate transporter
INE82_RS05130	COG0586	Pfam SNARE associated Golgi protein
INE82_RS05180	COG0038	chloride channel
INE82_RS05185	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
INE82_RS05210	COG3119	arylsulfatase activity
INE82_RS05220	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE82_RS05225	COG0702	epimerase
INE82_RS05230	COG4771	TonB-dependent receptor
INE82_RS05240	COG5434	Belongs to the glycosyl hydrolase 28 family
INE82_RS05245	COG3292	Two component regulator propeller
INE82_RS05245	COG2205	protein histidine kinase activity
INE82_RS05245	COG0745	RESPONSE REGULATOR receiver
INE82_RS05250	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
INE82_RS05255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INE82_RS05265	COG3250	beta-galactosidase activity
INE82_RS05280	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE82_RS05285	COG1629	transport
INE82_RS05285	COG4206	TonB-dependent receptor
INE82_RS05295	COG5002	protein histidine kinase activity
INE82_RS05320	COG1760	l-serine dehydratase
INE82_RS05325	COG0598	Magnesium transport protein CorA
INE82_RS05330	COG1193	negative regulation of DNA recombination
INE82_RS05385	COG4804	nuclease activity
INE82_RS05395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS05410	COG3250	beta-galactosidase activity
INE82_RS05420	COG0668	transmembrane transport
INE82_RS05425	COG1523	belongs to the glycosyl hydrolase 13 family
INE82_RS05435	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
INE82_RS05445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS05455	COG1538	Outer membrane efflux protein
INE82_RS05460	COG0456	acetyltransferase
INE82_RS05470	COG3189	MarR family transcriptional regulator
INE82_RS05475	COG0561	phosphatase activity
INE82_RS05480	COG1169	isochorismate synthase
INE82_RS05485	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
INE82_RS05490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
INE82_RS05495	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS05500	COG0318	PFAM AMP-dependent synthetase and ligase
INE82_RS05515	COG4206	TonB-dependent receptor
INE82_RS05515	COG1629	transport
INE82_RS05555	COG0783	Belongs to the Dps family
INE82_RS05560	COG0583	DNA-binding transcription factor activity
INE82_RS05570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INE82_RS05600	COG4771	TonB-dependent receptor
INE82_RS05605	COG0561	phosphatase activity
INE82_RS05675	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS05680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INE82_RS05685	COG1882	Formate acetyltransferase
INE82_RS05700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INE82_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS05745	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS05750	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
INE82_RS05775	COG2205	protein histidine kinase activity
INE82_RS05775	COG2205	protein histidine kinase activity
INE82_RS05775	COG3292	Two component regulator propeller
INE82_RS05775	COG0745	RESPONSE REGULATOR receiver
INE82_RS05775	COG3292	Two component regulator propeller
INE82_RS05775	COG0745	RESPONSE REGULATOR receiver
INE82_RS05780	COG1595	DNA-templated transcription, initiation
INE82_RS05785	COG1629	transport
INE82_RS05785	COG4206	TonB-dependent receptor
INE82_RS05810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE82_RS05820	COG1253	flavin adenine dinucleotide binding
INE82_RS05825	COG0501	Belongs to the peptidase M48B family
INE82_RS05850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE82_RS05855	COG0482	sulfurtransferase activity
INE82_RS05860	COG2197	response regulator
INE82_RS05870	COG1757	Na H antiporter
INE82_RS05885	COG2814	Major facilitator Superfamily
INE82_RS05890	COG4953	penicillin-binding protein 1C
INE82_RS05895	COG2373	Large extracellular alpha-helical protein
INE82_RS05900	COG0545	Peptidyl-prolyl cis-trans isomerase
INE82_RS06200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
INE82_RS06205	COG1410	methionine synthase
INE82_RS06205	COG0646	methionine synthase
INE82_RS06210	COG0778	Nitroreductase
INE82_RS06215	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE82_RS06225	COG0572	uridine kinase
INE82_RS06235	COG4232	protein-disulfide reductase activity
INE82_RS06240	COG1741	Belongs to the pirin family
INE82_RS06255	COG1629	transport
INE82_RS06260	COG0702	epimerase
INE82_RS06285	COG2271	Major facilitator Superfamily
INE82_RS06305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
INE82_RS06310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
INE82_RS06315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
INE82_RS06320	COG0131	Imidazoleglycerol-phosphate dehydratase
INE82_RS06330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE82_RS06330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
INE82_RS06335	COG4771	TonB-dependent receptor
INE82_RS06365	COG1404	Belongs to the peptidase S8 family
INE82_RS06385	COG1773	rubredoxin
INE82_RS06385	COG1592	Rubrerythrin
INE82_RS06415	COG3591	Belongs to the peptidase S1B family
INE82_RS06420	COG3591	Belongs to the peptidase S1B family
INE82_RS06425	COG0641	radical SAM
INE82_RS06455	COG0420	3'-5' exonuclease activity
INE82_RS06465	COG1408	metallophosphoesterase
INE82_RS06480	COG1410	methionine synthase
INE82_RS06480	COG0646	methionine synthase
INE82_RS06490	COG0463	Glycosyl transferase, family 2
INE82_RS06495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INE82_RS06505	COG1032	radical SAM domain protein
INE82_RS06525	COG0363	glucosamine-6-phosphate deaminase activity
INE82_RS06530	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE82_RS06565	COG2205	protein histidine kinase activity
INE82_RS06565	COG0745	RESPONSE REGULATOR receiver
INE82_RS06565	COG3292	Two component regulator propeller
INE82_RS06570	COG1629	transport
INE82_RS06580	COG0702	epimerase
INE82_RS06595	COG4771	TonB-dependent receptor
INE82_RS06650	COG0811	peptide transport
INE82_RS06655	COG0848	biopolymer transport protein
INE82_RS06700	COG1131	(ABC) transporter
INE82_RS06735	COG1752	Esterase of the alpha-beta hydrolase superfamily
INE82_RS06775	COG0508	dehydrogenase complex catalyzes the overall conversion of
INE82_RS06780	COG0022	dehydrogenase e1 component
INE82_RS06790	COG2264	protein methyltransferase activity
INE82_RS06810	COG0590	tRNA wobble adenosine to inosine editing
INE82_RS06815	COG0673	inositol 2-dehydrogenase activity
INE82_RS06840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
INE82_RS06885	COG2425	protein containing a von Willebrand factor type A (vWA) domain
INE82_RS06900	COG1501	Belongs to the glycosyl hydrolase 31 family
INE82_RS06905	COG5012	cobalamin binding
INE82_RS06925	COG0698	ribose 5-phosphate isomerase
INE82_RS06930	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INE82_RS06945	COG1070	Carbohydrate kinase
INE82_RS06950	COG2160	L-arabinose isomerase activity
INE82_RS06980	COG0702	epimerase
INE82_RS06985	COG1629	transport
INE82_RS06985	COG4206	TonB-dependent receptor
INE82_RS06990	COG0702	epimerase
INE82_RS06995	COG1629	transport
INE82_RS06995	COG4206	TonB-dependent receptor
INE82_RS07005	COG3292	Two component regulator propeller
INE82_RS07005	COG2205	protein histidine kinase activity
INE82_RS07005	COG0745	RESPONSE REGULATOR receiver
INE82_RS07010	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS07020	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS07025	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
INE82_RS07040	COG1482	cell wall glycoprotein biosynthetic process
INE82_RS07045	COG4974	Belongs to the 'phage' integrase family
INE82_RS07075	COG1086	Polysaccharide biosynthesis protein
INE82_RS07105	COG0438	transferase activity, transferring glycosyl groups
INE82_RS07130	COG0297	glycogen (starch) synthase activity
INE82_RS07130	COG0438	transferase activity, transferring glycosyl groups
INE82_RS07145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE82_RS07175	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS07215	COG4221	oxidoreductase activity
INE82_RS07225	COG1218	3'(2'),5'-bisphosphate nucleotidase
INE82_RS07230	COG0471	metal ion transport
INE82_RS07230	COG3273	potassium ion transport
INE82_RS07235	COG0529	Catalyzes the synthesis of activated sulfate
INE82_RS07240	COG0175	sulfate reduction
INE82_RS07245	COG2895	sulfate adenylyltransferase (ATP) activity
INE82_RS07265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
INE82_RS07270	COG0242	peptide deformylase activity
INE82_RS07280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
INE82_RS07285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
INE82_RS07290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
INE82_RS07295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
INE82_RS07305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INE82_RS07310	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
INE82_RS07315	COG1013	pyruvate-flavodoxin oxidoreductase activity
INE82_RS07315	COG0674	pyruvate-flavodoxin oxidoreductase activity
INE82_RS07315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INE82_RS07315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
INE82_RS07325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
INE82_RS07340	COG1940	carbohydrate kinase activity
INE82_RS07345	COG2081	HI0933 family
INE82_RS07370	COG1629	transport
INE82_RS07375	COG0702	epimerase
INE82_RS07395	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS07415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS07420	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS07430	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS07440	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS07460	COG4771	TonB-dependent receptor
INE82_RS07535	COG1629	transport
INE82_RS07560	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS07565	COG2755	lipolytic protein G-D-S-L family
INE82_RS07565	COG0657	acetylesterase activity
INE82_RS07575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS07580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS07585	COG3250	beta-galactosidase activity
INE82_RS07620	COG1442	glycosyl transferase family 8
INE82_RS07620	COG1216	Glycosyl transferase, family 2
INE82_RS07630	COG0438	transferase activity, transferring glycosyl groups
INE82_RS07645	COG0438	transferase activity, transferring glycosyl groups
INE82_RS07650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
INE82_RS07655	COG0438	transferase activity, transferring glycosyl groups
INE82_RS07675	COG1629	transport
INE82_RS07680	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE82_RS07685	COG0484	heat shock protein binding
INE82_RS07690	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
INE82_RS07695	COG0488	(ABC) transporter
INE82_RS07710	COG2183	response to ionizing radiation
INE82_RS07715	COG2202	Pas domain
INE82_RS07715	COG2205	protein histidine kinase activity
INE82_RS07720	COG0737	Belongs to the 5'-nucleotidase family
INE82_RS07760	COG2985	domain, Protein
INE82_RS07760	COG0490	domain, Protein
INE82_RS07765	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
INE82_RS07775	COG0318	PFAM AMP-dependent synthetase and ligase
INE82_RS07785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE82_RS07790	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
INE82_RS07795	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
INE82_RS07800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
INE82_RS07810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
INE82_RS07820	COG2837	iron assimilation
INE82_RS07825	COG2135	peptidase activity
INE82_RS07830	COG3279	Response regulator of the LytR AlgR family
INE82_RS07840	COG1136	(ABC) transporter
INE82_RS07840	COG0577	efflux transmembrane transporter activity
INE82_RS07845	COG1136	(ABC) transporter
INE82_RS07875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INE82_RS07885	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INE82_RS07910	COG0501	Belongs to the peptidase M48B family
INE82_RS07915	COG1704	LemA family
INE82_RS07930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INE82_RS07935	COG2885	chlorophyll binding
INE82_RS07940	COG0534	Mate efflux family protein
INE82_RS07945	COG2755	lipolytic protein G-D-S-L family
INE82_RS07945	COG0657	acetylesterase activity
INE82_RS07955	COG1162	GTPase activity
INE82_RS07975	COG0488	(ABC) transporter
INE82_RS08005	COG1215	transferase activity, transferring glycosyl groups
INE82_RS08010	COG0438	transferase activity, transferring glycosyl groups
INE82_RS08015	COG0438	transferase activity, transferring glycosyl groups
INE82_RS08020	COG1442	glycosyl transferase family 8
INE82_RS08030	COG2244	polysaccharide biosynthetic process
INE82_RS08035	COG1216	Glycosyl transferase, family 2
INE82_RS08035	COG1442	glycosyl transferase family 8
INE82_RS08080	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS08090	COG1215	transferase activity, transferring glycosyl groups
INE82_RS08125	COG1805	sodium ion transport
INE82_RS08130	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
INE82_RS08140	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
INE82_RS08145	COG2871	sodium ion transport
INE82_RS08150	COG0513	Belongs to the DEAD box helicase family
INE82_RS08155	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
INE82_RS08170	COG1739	Uncharacterized protein family UPF0029
INE82_RS08185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
INE82_RS08185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
INE82_RS08190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INE82_RS08195	COG0357	Ribosomal RNA small subunit methyltransferase G
INE82_RS08240	COG2217	Heavy metal translocating P-type atpase
INE82_RS08250	COG0321	lipoyl(octanoyl) transferase activity
INE82_RS08280	COG0218	Necessary for normal cell division and for the maintenance of normal septation
INE82_RS08290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
INE82_RS08305	COG1678	Uncharacterized ACR, COG1678
INE82_RS08325	COG3275	phosphorelay sensor kinase activity
INE82_RS08355	COG3969	phosphoadenosine phosphosulfate
INE82_RS08360	COG1475	DNA binding
INE82_RS08425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INE82_RS08445	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS08470	COG1629	transport
INE82_RS08470	COG4206	TonB-dependent receptor
INE82_RS08500	COG1629	transport
INE82_RS08500	COG4206	TonB-dependent receptor
INE82_RS08535	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE82_RS08540	COG3537	Alpha-1,2-mannosidase
INE82_RS08555	COG1629	transport
INE82_RS08555	COG4206	TonB-dependent receptor
INE82_RS08560	COG0702	epimerase
INE82_RS08585	COG3408	Glycogen debranching enzyme
INE82_RS08605	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS08610	COG3408	Glycogen debranching enzyme
INE82_RS08620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE82_RS08630	COG0167	dihydroorotate dehydrogenase activity
INE82_RS08635	COG0657	acetylesterase activity
INE82_RS08635	COG2755	lipolytic protein G-D-S-L family
INE82_RS08695	COG3250	beta-galactosidase activity
INE82_RS08705	COG0784	Response regulator, receiver
INE82_RS08705	COG2205	protein histidine kinase activity
INE82_RS08715	COG3250	beta-galactosidase activity
INE82_RS08720	COG0745	RESPONSE REGULATOR receiver
INE82_RS08725	COG5002	protein histidine kinase activity
INE82_RS08805	COG1538	Outer membrane efflux protein
INE82_RS08825	COG3250	beta-galactosidase activity
INE82_RS08830	COG0745	RESPONSE REGULATOR receiver
INE82_RS08830	COG3292	Two component regulator propeller
INE82_RS08830	COG2205	protein histidine kinase activity
INE82_RS08860	COG2966	Psort location CytoplasmicMembrane, score
INE82_RS08875	COG0300	oxidoreductase activity
INE82_RS08885	COG1011	Hydrolase
INE82_RS08950	COG0745	RESPONSE REGULATOR receiver
INE82_RS08950	COG2205	protein histidine kinase activity
INE82_RS08950	COG3292	Two component regulator propeller
INE82_RS08950	COG0745	RESPONSE REGULATOR receiver
INE82_RS08950	COG2205	protein histidine kinase activity
INE82_RS08950	COG3292	Two component regulator propeller
INE82_RS08965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS08980	COG0442	prolyl-tRNA aminoacylation
INE82_RS08985	COG0745	RESPONSE REGULATOR receiver
INE82_RS08990	COG2205	protein histidine kinase activity
INE82_RS09025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
INE82_RS09035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
INE82_RS09040	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INE82_RS09050	COG0552	protein localization to endoplasmic reticulum
INE82_RS09055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE82_RS09060	COG0776	regulation of translation
INE82_RS09065	COG0776	regulation of translation
INE82_RS09070	COG0714	Associated with various cellular activities
INE82_RS09085	COG2304	oxidoreductase activity
INE82_RS09135	COG0326	Molecular chaperone. Has ATPase activity
INE82_RS09160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INE82_RS09165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
INE82_RS09170	COG0336	Belongs to the RNA methyltransferase TrmD family
INE82_RS09175	COG0167	dihydroorotate dehydrogenase activity
INE82_RS09180	COG0543	2 iron, 2 sulfur cluster binding
INE82_RS09195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INE82_RS09225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
INE82_RS09245	COG1132	(ABC) transporter
INE82_RS09275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
INE82_RS09280	COG1597	lipid kinase activity
INE82_RS09285	COG0156	8-amino-7-oxononanoate synthase activity
INE82_RS09300	COG4771	TonB-dependent receptor
INE82_RS09320	COG1136	(ABC) transporter
INE82_RS09320	COG0577	efflux transmembrane transporter activity
INE82_RS09340	COG1136	(ABC) transporter
INE82_RS09365	COG3852	Histidine kinase
INE82_RS09375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
INE82_RS09450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
INE82_RS09455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
INE82_RS09475	COG0560	Phosphoserine phosphatase
INE82_RS09475	COG3830	Belongs to the UPF0237 family
INE82_RS09480	COG0513	Belongs to the DEAD box helicase family
INE82_RS09510	COG0246	Mannitol dehydrogenase
INE82_RS09520	COG1904	glucuronate isomerase
INE82_RS09535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INE82_RS09560	COG3015	lipoprotein NlpE involved in copper resistance
INE82_RS09590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INE82_RS09605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
INE82_RS09615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
INE82_RS09625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE82_RS09625	COG3153	acetyltransferase
INE82_RS09630	COG0477	Major facilitator Superfamily
INE82_RS09630	COG2814	Major facilitator Superfamily
INE82_RS09635	COG2115	Belongs to the xylose isomerase family
INE82_RS09650	COG0351	phosphomethylpyrimidine kinase
INE82_RS09655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INE82_RS09660	COG0045	succinate-CoA ligase (ADP-forming) activity
INE82_RS09665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INE82_RS09685	COG0724	RNA recognition motif
INE82_RS09710	COG2326	polyphosphate kinase activity
INE82_RS09720	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
INE82_RS09745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
INE82_RS09760	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INE82_RS09765	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INE82_RS09775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE82_RS09800	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS09820	COG0745	RESPONSE REGULATOR receiver
INE82_RS09820	COG2205	protein histidine kinase activity
INE82_RS09820	COG3292	Two component regulator propeller
INE82_RS09880	COG2244	polysaccharide biosynthetic process
INE82_RS09905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INE82_RS09925	COG3958	Transketolase
INE82_RS09930	COG3959	Transketolase, thiamine diphosphate binding domain
INE82_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS09940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INE82_RS09955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
INE82_RS09975	COG0535	radical SAM domain protein
INE82_RS10010	COG3250	beta-galactosidase activity
INE82_RS10015	COG3119	arylsulfatase activity
INE82_RS10025	COG4206	TonB-dependent receptor
INE82_RS10025	COG1629	transport
INE82_RS10050	COG2205	protein histidine kinase activity
INE82_RS10055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INE82_RS10070	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
INE82_RS10085	COG0540	Belongs to the ATCase OTCase family
INE82_RS10090	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
INE82_RS10105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
INE82_RS10110	COG2759	Belongs to the formate--tetrahydrofolate ligase family
INE82_RS10115	COG2985	domain, Protein
INE82_RS10155	COG2207	Transcriptional regulator
INE82_RS10180	COG2431	L-lysine efflux transmembrane transporter activity
INE82_RS10185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INE82_RS10195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
INE82_RS10200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
INE82_RS10205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE82_RS10210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
INE82_RS10215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE82_RS10220	COG0356	it plays a direct role in the translocation of protons across the membrane
INE82_RS10230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
INE82_RS10235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
INE82_RS10260	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS10275	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
INE82_RS10295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INE82_RS10305	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
INE82_RS10315	COG0534	Mate efflux family protein
INE82_RS10325	COG1136	(ABC) transporter
INE82_RS10360	COG1151	hydroxylamine reductase activity
INE82_RS10365	COG2233	PERMEase
INE82_RS10370	COG3263	regulation of cellular component size
INE82_RS10375	COG0318	PFAM AMP-dependent synthetase and ligase
INE82_RS10380	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS10385	COG0745	RESPONSE REGULATOR receiver
INE82_RS10390	COG5002	protein histidine kinase activity
INE82_RS10410	COG3118	belongs to the thioredoxin family
INE82_RS10415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INE82_RS10460	COG2249	NAD(P)H dehydrogenase (quinone) activity
INE82_RS10480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS10490	COG0681	Belongs to the peptidase S26 family
INE82_RS10510	COG0681	Belongs to the peptidase S26 family
INE82_RS10585	COG5002	protein histidine kinase activity
INE82_RS10595	COG0352	thiamine-phosphate diphosphorylase activity
INE82_RS10600	COG2022	thiamine diphosphate biosynthetic process
INE82_RS10605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
INE82_RS10610	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INE82_RS10615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
INE82_RS10620	COG0352	thiamine-phosphate diphosphorylase activity
INE82_RS10635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INE82_RS10635	COG0574	Belongs to the PEP-utilizing enzyme family
INE82_RS10640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INE82_RS10645	COG0564	pseudouridine synthase activity
INE82_RS10665	COG0024	Methionine aminopeptidase
INE82_RS10685	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
INE82_RS10695	COG0481	GTPase activity
INE82_RS10710	COG0708	Exodeoxyribonuclease III
INE82_RS10725	COG0217	transcriptional regulatory protein
INE82_RS10730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE82_RS10730	COG0072	phenylalanine-tRNA ligase activity
INE82_RS10735	COG0305	Participates in initiation and elongation during chromosome replication
INE82_RS10740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
INE82_RS10745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INE82_RS10750	COG4657	Part of a membrane complex involved in electron transport
INE82_RS10755	COG4660	Part of a membrane complex involved in electron transport
INE82_RS10760	COG4659	FMN binding
INE82_RS10765	COG4658	electron transport chain
INE82_RS10770	COG4656	Part of a membrane complex involved in electron transport
INE82_RS10805	COG0438	transferase activity, transferring glycosyl groups
INE82_RS10810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INE82_RS10820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INE82_RS10825	COG1216	Glycosyl transferase, family 2
INE82_RS10845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
INE82_RS10855	COG1086	Polysaccharide biosynthesis protein
INE82_RS10865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
INE82_RS10875	COG1086	Polysaccharide biosynthesis protein
INE82_RS10930	COG0504	CTP synthase activity
INE82_RS10935	COG0706	membrane insertase activity
INE82_RS10940	COG0534	Mate efflux family protein
INE82_RS10945	COG0823	Involved in the tonB-independent uptake of proteins
INE82_RS10945	COG1506	peptidase
INE82_RS10965	COG1983	PspC domain protein
INE82_RS10970	COG1695	Transcriptional regulator
INE82_RS10980	COG3104	oligopeptide transport
INE82_RS10985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INE82_RS10995	COG0860	N-Acetylmuramoyl-L-alanine amidase
INE82_RS10995	COG1388	LysM domain
INE82_RS11025	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
INE82_RS11030	COG0556	nucleotide-excision repair
INE82_RS11045	COG2949	membrane
INE82_RS11050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
INE82_RS11060	COG0842	Transport permease protein
INE82_RS11065	COG0842	Transport permease protein
INE82_RS11070	COG1131	(ABC) transporter
INE82_RS11085	COG1917	Cupin 2, conserved barrel domain protein
INE82_RS11085	COG2207	Transcriptional regulator
INE82_RS11095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
INE82_RS11100	COG0505	Belongs to the CarA family
INE82_RS11110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
INE82_RS11115	COG0067	glutamate synthase
INE82_RS11115	COG0069	glutamate synthase activity
INE82_RS11115	COG0070	glutamate synthase
INE82_RS11125	COG0367	asparagine synthase
INE82_RS11140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
INE82_RS11145	COG0436	Aminotransferase
INE82_RS11155	COG0347	Belongs to the P(II) protein family
INE82_RS11160	COG0004	ammonium transporteR
INE82_RS11175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
INE82_RS11185	COG0471	metal ion transport
INE82_RS11185	COG0490	domain, Protein
INE82_RS11195	COG1979	alcohol dehydrogenase
INE82_RS11205	COG0133	tryptophan synthase activity
INE82_RS11210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INE82_RS11220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INE82_RS11225	COG0134	indole-3-glycerol-phosphate synthase activity
INE82_RS11230	COG0135	phosphoribosylanthranilate isomerase activity
INE82_RS11235	COG0159	tryptophan synthase activity
INE82_RS11240	COG0252	asparaginase activity
INE82_RS11250	COG2205	protein histidine kinase activity
INE82_RS11250	COG3292	Two component regulator propeller
INE82_RS11250	COG0745	RESPONSE REGULATOR receiver
INE82_RS11255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INE82_RS11265	COG0110	maltose O-acetyltransferase activity
INE82_RS11270	COG2197	response regulator
INE82_RS11280	COG0138	bifunctional purine biosynthesis protein purh
INE82_RS11290	COG0716	FMN binding
INE82_RS11315	COG1132	(ABC) transporter
INE82_RS11330	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS11340	COG4771	TonB-dependent receptor
INE82_RS11350	COG4771	TonB-dependent receptor
INE82_RS11360	COG0490	domain, Protein
INE82_RS11360	COG2985	domain, Protein
INE82_RS11365	COG1230	cation diffusion facilitator family transporter
INE82_RS11380	COG4771	TonB-dependent receptor
INE82_RS11385	COG1429	ligase activity, forming nitrogen-metal bonds
INE82_RS11420	COG1609	Transcriptional regulator
INE82_RS11425	COG2721	sulfolactate sulfo-lyase activity
INE82_RS11500	COG1733	regulation of RNA biosynthetic process
INE82_RS11510	COG2205	protein histidine kinase activity
INE82_RS11510	COG0784	Response regulator, receiver
INE82_RS11510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE82_RS11510	COG2198	Histidine kinase
INE82_RS11520	COG3275	phosphorelay sensor kinase activity
INE82_RS11545	COG0228	four-way junction DNA binding
INE82_RS11550	COG2188	Transcriptional regulator
INE82_RS11555	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
INE82_RS11565	COG1070	Carbohydrate kinase
INE82_RS11575	COG0738	Major facilitator superfamily
INE82_RS11635	COG1177	transmembrane transport
INE82_RS11640	COG1176	ABC-type spermidine putrescine transport system, permease component I
INE82_RS11645	COG3842	ATPase activity
INE82_RS11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE82_RS11655	COG0058	SHG alpha-glucan phosphorylase activity
INE82_RS11665	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE82_RS11685	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
INE82_RS11760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INE82_RS11765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE82_RS11770	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS11785	COG1295	ribonuclease BN
INE82_RS11800	COG0704	Plays a role in the regulation of phosphate uptake
INE82_RS11805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INE82_RS11810	COG0581	inorganic phosphate transmembrane transporter activity
INE82_RS11815	COG0573	inorganic phosphate transmembrane transporter activity
INE82_RS11825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INE82_RS11835	COG0586	Pfam SNARE associated Golgi protein
INE82_RS11845	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INE82_RS11860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INE82_RS11865	COG0167	dihydroorotate dehydrogenase activity
INE82_RS11870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
INE82_RS11915	COG1442	glycosyl transferase family 8
INE82_RS11915	COG1216	Glycosyl transferase, family 2
INE82_RS11925	COG5039	Polysaccharide pyruvyl transferase
INE82_RS11970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INE82_RS11975	COG0497	DNA recombination
INE82_RS11990	COG0592	DNA-directed DNA polymerase activity
INE82_RS12005	COG0321	lipoyl(octanoyl) transferase activity
INE82_RS12005	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INE82_RS12010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
INE82_RS12020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE82_RS12025	COG0156	8-amino-7-oxononanoate synthase activity
INE82_RS12040	COG0019	diaminopimelate decarboxylase activity
INE82_RS12045	COG0527	aspartate kinase activity
INE82_RS12050	COG2884	Cell division ATP-binding protein ftsE
INE82_RS12055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
INE82_RS12055	COG0140	phosphoribosyl-ATP diphosphatase activity
INE82_RS12060	COG0107	imidazoleglycerol-phosphate synthase activity
INE82_RS12065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
INE82_RS12070	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
INE82_RS12075	COG0788	formyltetrahydrofolate deformylase activity
INE82_RS12090	COG0693	protein deglycase activity
INE82_RS12095	COG0656	L-ascorbic acid biosynthetic process
INE82_RS12115	COG0534	Mate efflux family protein
INE82_RS12120	COG2076	Multidrug Resistance protein
INE82_RS12160	COG3546	catalase activity
INE82_RS12190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
INE82_RS12220	COG0823	Involved in the tonB-independent uptake of proteins
INE82_RS12220	COG4946	Tricorn protease homolog
INE82_RS12220	COG1506	peptidase
INE82_RS12225	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
INE82_RS12230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INE82_RS12250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INE82_RS12260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
INE82_RS12275	COG4771	TonB-dependent receptor
INE82_RS12335	COG1312	Catalyzes the dehydration of D-mannonate
INE82_RS12340	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS12345	COG1609	Transcriptional regulator
INE82_RS12360	COG1929	Belongs to the glycerate kinase type-1 family
INE82_RS12365	COG2223	nitrite transmembrane transporter activity
INE82_RS12375	COG4771	TonB-dependent receptor
INE82_RS12385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
INE82_RS12385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INE82_RS12400	COG2226	methyltransferase
INE82_RS12410	COG0784	Response regulator, receiver
INE82_RS12410	COG5002	protein histidine kinase activity
INE82_RS12415	COG0511	ligase activity, forming carbon-carbon bonds
INE82_RS12420	COG0439	Biotin carboxylase
INE82_RS12425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE82_RS12440	COG1620	l-lactate permease
INE82_RS12445	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
INE82_RS12450	COG1690	Belongs to the RtcB family
INE82_RS12490	COG0110	maltose O-acetyltransferase activity
INE82_RS12500	COG0577	efflux transmembrane transporter activity
INE82_RS12505	COG0577	efflux transmembrane transporter activity
INE82_RS12505	COG1136	(ABC) transporter
INE82_RS12520	COG2204	response regulator
INE82_RS12530	COG0628	permease
INE82_RS12535	COG1215	transferase activity, transferring glycosyl groups
INE82_RS12545	COG0569	domain protein
INE82_RS12545	COG0189	ligase activity
INE82_RS12550	COG1136	(ABC) transporter
INE82_RS12550	COG0577	efflux transmembrane transporter activity
INE82_RS12555	COG0436	Aminotransferase
INE82_RS12570	COG0488	(ABC) transporter
INE82_RS12585	COG0745	RESPONSE REGULATOR receiver
INE82_RS12590	COG5002	protein histidine kinase activity
INE82_RS12635	COG3033	Beta-eliminating lyase
INE82_RS12660	COG0629	single-stranded DNA binding
INE82_RS12665	COG1194	a g-specific adenine glycosylase
INE82_RS12675	COG1530	ribonuclease E activity
INE82_RS12680	COG2885	chlorophyll binding
INE82_RS12695	COG2885	chlorophyll binding
INE82_RS12745	COG0305	Participates in initiation and elongation during chromosome replication
INE82_RS12760	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS12780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INE82_RS12790	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
INE82_RS12805	COG4191	Histidine kinase
INE82_RS12810	COG2204	response regulator
INE82_RS12820	COG5002	protein histidine kinase activity
INE82_RS12820	COG2205	protein histidine kinase activity
INE82_RS12820	COG0784	Response regulator, receiver
INE82_RS12840	COG1136	(ABC) transporter
INE82_RS12850	COG1252	NADH dehydrogenase
INE82_RS12855	COG1705	Flagellar rod assembly protein muramidase FlgJ
INE82_RS12870	COG3059	membrane
INE82_RS12875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INE82_RS12880	COG3292	Two component regulator propeller
INE82_RS12880	COG2205	protein histidine kinase activity
INE82_RS12880	COG0745	RESPONSE REGULATOR receiver
INE82_RS12890	COG3250	beta-galactosidase activity
INE82_RS12895	COG0488	(ABC) transporter
INE82_RS12920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INE82_RS12930	COG0739	heme binding
INE82_RS12935	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
INE82_RS12940	COG4206	TonB-dependent receptor
INE82_RS12940	COG1629	transport
INE82_RS12950	COG0686	Belongs to the AlaDH PNT family
INE82_RS12995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
INE82_RS13010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
INE82_RS13020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
INE82_RS13050	COG1595	DNA-templated transcription, initiation
INE82_RS13065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INE82_RS13070	COG1741	Belongs to the pirin family
INE82_RS13075	COG0259	pyridoxamine-phosphate oxidase activity
INE82_RS13130	COG0456	acetyltransferase
INE82_RS13185	COG0358	DNA primase activity
INE82_RS13420	COG2003	Belongs to the UPF0758 family
INE82_RS13425	COG0582	viral genome integration into host DNA
INE82_RS13430	COG5492	domain, Protein
INE82_RS13455	COG1918	ferrous iron import across plasma membrane
INE82_RS13455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INE82_RS13460	COG0037	tRNA processing
INE82_RS13475	COG3119	arylsulfatase activity
INE82_RS13485	COG2205	protein histidine kinase activity
INE82_RS13485	COG2202	Pas domain
INE82_RS13490	COG0534	Mate efflux family protein
INE82_RS13495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INE82_RS13505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INE82_RS13510	COG1858	cytochrome C peroxidase
INE82_RS13515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
INE82_RS13530	COG1983	PspC domain protein
INE82_RS13535	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INE82_RS13560	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE82_RS13595	COG3119	arylsulfatase activity
INE82_RS13600	COG0668	transmembrane transport
INE82_RS13605	COG3119	arylsulfatase activity
INE82_RS13615	COG3250	beta-galactosidase activity
INE82_RS13620	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS13625	COG3119	arylsulfatase activity
INE82_RS13635	COG0702	epimerase
INE82_RS13640	COG4206	TonB-dependent receptor
INE82_RS13640	COG1629	transport
INE82_RS13650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
INE82_RS13655	COG1660	Displays ATPase and GTPase activities
INE82_RS13660	COG3292	Two component regulator propeller
INE82_RS13660	COG2205	protein histidine kinase activity
INE82_RS13660	COG0745	RESPONSE REGULATOR receiver
INE82_RS13660	COG3292	Two component regulator propeller
INE82_RS13660	COG2205	protein histidine kinase activity
INE82_RS13660	COG0745	RESPONSE REGULATOR receiver
INE82_RS13665	COG3119	arylsulfatase activity
INE82_RS13710	COG1091	dTDP-4-dehydrorhamnose reductase activity
INE82_RS13725	COG0438	transferase activity, transferring glycosyl groups
INE82_RS13735	COG1216	Glycosyl transferase, family 2
INE82_RS13745	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
INE82_RS13790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INE82_RS13795	COG1830	Aldolase
INE82_RS13800	COG0588	phosphoglycerate mutase activity
INE82_RS13805	COG0784	Response regulator, receiver
INE82_RS13805	COG2205	protein histidine kinase activity
INE82_RS13810	COG1119	ATPase activity
INE82_RS13815	COG1523	belongs to the glycosyl hydrolase 13 family
INE82_RS13820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
INE82_RS13835	COG0560	Phosphoserine phosphatase
INE82_RS13850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
INE82_RS13855	COG2814	Major facilitator Superfamily
INE82_RS13860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INE82_RS13865	COG0126	phosphoglycerate kinase activity
INE82_RS13885	COG0424	maF-like protein
INE82_RS13905	COG0778	Nitroreductase
INE82_RS13915	COG0288	reversible hydration of carbon dioxide
INE82_RS13925	COG4771	TonB-dependent receptor
INE82_RS13940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE82_RS13950	COG0511	ligase activity, forming carbon-carbon bonds
INE82_RS13955	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
INE82_RS13965	COG0191	fructose-bisphosphate aldolase activity
INE82_RS13970	COG0254	rRNA binding
INE82_RS13975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS13980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INE82_RS14050	COG1216	Glycosyl transferase, family 2
INE82_RS14070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
INE82_RS14080	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
INE82_RS14085	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
INE82_RS14110	COG4750	Nucleotidyl transferase
INE82_RS14150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
INE82_RS14165	COG1280	lysine exporter protein (LysE YggA)
INE82_RS14175	COG0745	RESPONSE REGULATOR receiver
INE82_RS14175	COG3292	Two component regulator propeller
INE82_RS14175	COG0745	RESPONSE REGULATOR receiver
INE82_RS14175	COG2205	protein histidine kinase activity
INE82_RS14175	COG3292	Two component regulator propeller
INE82_RS14175	COG2205	protein histidine kinase activity
INE82_RS14190	COG1649	PFAM Uncharacterised BCR, COG1649
INE82_RS14215	COG1966	Carbon starvation protein
INE82_RS14225	COG1649	PFAM Uncharacterised BCR, COG1649
INE82_RS14250	COG2113	Glycine betaine
INE82_RS14255	COG4176	ABC-type proline glycine betaine transport system permease component
INE82_RS14275	COG2205	protein histidine kinase activity
INE82_RS14275	COG0745	RESPONSE REGULATOR receiver
INE82_RS14275	COG3292	Two component regulator propeller
INE82_RS14285	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
INE82_RS14285	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
INE82_RS14295	COG1621	beta-fructofuranosidase activity
INE82_RS14310	COG0561	phosphatase activity
INE82_RS14315	COG4206	TonB-dependent receptor
INE82_RS14315	COG1629	transport
INE82_RS14325	COG1621	beta-fructofuranosidase activity
INE82_RS14340	COG3250	beta-galactosidase activity
INE82_RS14345	COG3537	Alpha-1,2-mannosidase
INE82_RS14370	COG1629	transport
INE82_RS14380	COG3250	beta-galactosidase activity
INE82_RS14390	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS14400	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS14410	COG1752	Esterase of the alpha-beta hydrolase superfamily
INE82_RS14415	COG0475	glutathione-regulated potassium exporter activity
INE82_RS14450	COG3279	Response regulator of the LytR AlgR family
INE82_RS14475	COG2205	protein histidine kinase activity
INE82_RS14480	COG2205	protein histidine kinase activity
INE82_RS14485	COG2205	protein histidine kinase activity
INE82_RS14500	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
INE82_RS14510	COG1960	acyl-CoA dehydrogenase activity
INE82_RS14530	COG1956	GAF domain-containing protein
INE82_RS14540	COG0484	heat shock protein binding
INE82_RS14565	COG1191	sigma factor activity
INE82_RS14580	COG0028	Belongs to the TPP enzyme family
INE82_RS14600	COG2885	chlorophyll binding
INE82_RS14620	COG0459	protein refolding
INE82_RS14625	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
INE82_RS14640	COG2205	protein histidine kinase activity
INE82_RS14640	COG5002	protein histidine kinase activity
INE82_RS14640	COG0784	Response regulator, receiver
INE82_RS14655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INE82_RS14665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
INE82_RS14670	COG0823	Involved in the tonB-independent uptake of proteins
INE82_RS14670	COG1506	peptidase
INE82_RS14680	COG0124	histidyl-tRNA synthetase
INE82_RS14695	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
INE82_RS14720	COG0514	ATP-dependent DNA helicase (RecQ)
INE82_RS14735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INE82_RS14745	COG0671	phosphoesterase, PA-phosphatase related
INE82_RS14760	COG0473	3-isopropylmalate dehydrogenase activity
INE82_RS14770	COG0066	3-isopropylmalate dehydratase activity
INE82_RS14775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INE82_RS14780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
INE82_RS14845	COG0463	Glycosyl transferase, family 2
INE82_RS14855	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS14865	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS14870	COG0702	epimerase
INE82_RS14875	COG4771	TonB-dependent receptor
INE82_RS14895	COG0616	signal peptide processing
INE82_RS14900	COG1663	tetraacyldisaccharide 4'-kinase activity
INE82_RS14905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
INE82_RS14910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
INE82_RS14930	COG0513	Belongs to the DEAD box helicase family
INE82_RS14935	COG2070	2-Nitropropane dioxygenase
INE82_RS14940	COG0724	RNA recognition motif
INE82_RS14955	COG3973	AAA domain
INE82_RS14975	COG1704	LemA family
INE82_RS14990	COG0534	Mate efflux family protein
INE82_RS15000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INE82_RS15010	COG1917	Cupin 2, conserved barrel domain protein
INE82_RS15010	COG4977	sequence-specific DNA binding
INE82_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS15050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
INE82_RS15060	COG0439	Biotin carboxylase
INE82_RS15065	COG0511	ligase activity, forming carbon-carbon bonds
INE82_RS15065	COG5016	pyruvate
INE82_RS15070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE82_RS15080	COG2855	membrane
INE82_RS15090	COG2873	o-acetylhomoserine
INE82_RS15130	COG1538	Outer membrane efflux protein
INE82_RS15160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INE82_RS15180	COG0024	Methionine aminopeptidase
INE82_RS15185	COG0617	tRNA 3'-terminal CCA addition
INE82_RS15205	COG0632	four-way junction helicase activity
INE82_RS15210	COG0673	inositol 2-dehydrogenase activity
INE82_RS15225	COG1272	protein, Hemolysin III
INE82_RS15240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
INE82_RS15245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
INE82_RS15245	COG1328	CTP reductase activity
INE82_RS15250	COG0602	queuosine metabolic process
INE82_RS15255	COG2814	Major facilitator Superfamily
INE82_RS15260	COG0750	zinc metalloprotease
INE82_RS15265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
INE82_RS15275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
INE82_RS15280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INE82_RS15300	COG0194	GDP metabolic process
INE82_RS15305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
INE82_RS15310	COG1408	metallophosphoesterase
INE82_RS15315	COG1575	Belongs to the MenA family. Type 1 subfamily
INE82_RS15320	COG1088	dTDP-glucose 4,6-dehydratase activity
INE82_RS15325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
INE82_RS15335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
INE82_RS15355	COG2205	protein histidine kinase activity
INE82_RS15385	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS15405	COG4771	TonB-dependent receptor
INE82_RS15410	COG1629	transport
INE82_RS15410	COG4206	TonB-dependent receptor
INE82_RS15420	COG0784	Response regulator, receiver
INE82_RS15420	COG2205	protein histidine kinase activity
INE82_RS15425	COG0488	(ABC) transporter
INE82_RS15465	COG1595	DNA-templated transcription, initiation
INE82_RS15480	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
INE82_RS15490	COG1522	sequence-specific DNA binding
INE82_RS15520	COG0811	peptide transport
INE82_RS15530	COG0084	hydrolase, TatD family'
INE82_RS15550	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
INE82_RS15555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
INE82_RS15560	COG0205	6-phosphofructokinase activity
INE82_RS15585	COG0372	Belongs to the citrate synthase family
INE82_RS15590	COG0538	isocitrate dehydrogenase activity
INE82_RS15595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INE82_RS15600	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE82_RS15605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
INE82_RS15620	COG0028	Belongs to the TPP enzyme family
INE82_RS15625	COG0129	dihydroxy-acid dehydratase activity
INE82_RS15630	COG1047	Peptidyl-prolyl cis-trans
INE82_RS15635	COG3681	Belongs to the UPF0597 family
INE82_RS15655	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
INE82_RS15700	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE82_RS15700	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE82_RS15705	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE82_RS15710	COG0569	domain protein
INE82_RS15710	COG2985	domain, Protein
INE82_RS15720	COG1492	cobalamin metabolic process
INE82_RS15760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INE82_RS15765	COG1120	ATPase activity
INE82_RS15775	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
INE82_RS15785	COG0534	Mate efflux family protein
INE82_RS15795	COG2188	Transcriptional regulator
INE82_RS15815	COG1629	transport
INE82_RS15815	COG4206	TonB-dependent receptor
INE82_RS15875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INE82_RS15880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
INE82_RS15885	COG0166	Belongs to the GPI family
INE82_RS15915	COG2502	aspartate--ammonia ligase
INE82_RS15920	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
INE82_RS15935	COG3876	Protein conserved in bacteria
INE82_RS15955	COG0860	N-Acetylmuramoyl-L-alanine amidase
INE82_RS15965	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
INE82_RS15970	COG0778	Nitroreductase
INE82_RS15980	COG1640	4-alpha-glucanotransferase
INE82_RS15995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
INE82_RS16015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE82_RS16020	COG0318	PFAM AMP-dependent synthetase and ligase
INE82_RS16055	COG0359	binds to the 23S rRNA
INE82_RS16060	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
INE82_RS16065	COG0360	Binds together with S18 to 16S ribosomal RNA
INE82_RS16090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INE82_RS16095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INE82_RS16150	COG1131	(ABC) transporter
INE82_RS16165	COG2431	L-lysine efflux transmembrane transporter activity
INE82_RS16175	COG1193	negative regulation of DNA recombination
INE82_RS16210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
INE82_RS16225	COG2234	aminopeptidase activity
INE82_RS16230	COG3250	beta-galactosidase activity
INE82_RS16250	COG0702	epimerase
INE82_RS16255	COG1629	transport
INE82_RS16270	COG3537	Alpha-1,2-mannosidase
INE82_RS16285	COG4206	TonB-dependent receptor
INE82_RS16285	COG1629	transport
INE82_RS16305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INE82_RS16310	COG0802	atpase or kinase
INE82_RS16335	COG0714	Associated with various cellular activities
INE82_RS16380	COG3118	belongs to the thioredoxin family
INE82_RS16385	COG4974	Belongs to the 'phage' integrase family
INE82_RS16420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INE82_RS16420	COG0551	DNA topoisomerase type I activity
INE82_RS16440	COG0784	Response regulator, receiver
INE82_RS16440	COG2205	protein histidine kinase activity
INE82_RS16440	COG2198	Histidine kinase
INE82_RS16440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE82_RS16545	COG0358	DNA primase activity
INE82_RS16620	COG0358	DNA primase activity
INE82_RS16690	COG0688	phosphatidylethanolamine metabolic process
INE82_RS16695	COG1183	phosphatidylcholine synthase activity
INE82_RS16715	COG0792	nuclease activity
INE82_RS16740	COG0534	Mate efflux family protein
INE82_RS16745	COG0528	UMP kinase activity
INE82_RS16780	COG0233	cytoplasmic translational termination
INE82_RS16785	COG1162	GTPase activity
INE82_RS16795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INE82_RS16815	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INE82_RS16815	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INE82_RS16825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INE82_RS16835	COG4206	TonB-dependent receptor
INE82_RS16835	COG1629	transport
INE82_RS16855	COG4206	TonB-dependent receptor
INE82_RS16855	COG1629	transport
INE82_RS16860	COG4974	Belongs to the 'phage' integrase family
INE82_RS16865	COG4771	TonB-dependent receptor
INE82_RS16875	COG2095	MarC family integral membrane protein
INE82_RS16890	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INE82_RS16900	COG1435	thymidine kinase activity
INE82_RS16905	COG0628	permease
INE82_RS16940	COG0534	Mate efflux family protein
INE82_RS17000	COG1396	sequence-specific DNA binding
INE82_RS17020	COG1501	Belongs to the glycosyl hydrolase 31 family
INE82_RS17035	COG0745	RESPONSE REGULATOR receiver
INE82_RS17035	COG3292	Two component regulator propeller
INE82_RS17035	COG2205	protein histidine kinase activity
INE82_RS17050	COG0702	epimerase
INE82_RS17055	COG1629	transport
INE82_RS17065	COG4771	TonB-dependent receptor
INE82_RS17075	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS17090	COG4771	TonB-dependent receptor
INE82_RS17125	COG0693	protein deglycase activity
INE82_RS17190	COG0110	maltose O-acetyltransferase activity
INE82_RS17200	COG1522	sequence-specific DNA binding
INE82_RS17225	COG0745	RESPONSE REGULATOR receiver
INE82_RS17225	COG2205	protein histidine kinase activity
INE82_RS17225	COG3292	Two component regulator propeller
INE82_RS17235	COG1629	transport
INE82_RS17260	COG2818	Glycosylase
INE82_RS17265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
INE82_RS17270	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
INE82_RS17280	COG0252	asparaginase activity
INE82_RS17290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INE82_RS17295	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
INE82_RS17305	COG4771	TonB-dependent receptor
INE82_RS17325	COG0826	peptidase U32
INE82_RS17330	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
INE82_RS17340	COG0436	Aminotransferase
INE82_RS17345	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
INE82_RS17365	COG0519	Catalyzes the synthesis of GMP from XMP
INE82_RS17370	COG5002	protein histidine kinase activity
INE82_RS17375	COG2205	protein histidine kinase activity
INE82_RS17385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
INE82_RS17395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
INE82_RS17440	COG3250	beta-galactosidase activity
INE82_RS17445	COG2204	response regulator
INE82_RS17450	COG0446	pyridine nucleotide-disulphide oxidoreductase
INE82_RS17475	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS17480	COG0737	Belongs to the 5'-nucleotidase family
INE82_RS17485	COG0737	Belongs to the 5'-nucleotidase family
INE82_RS17525	COG0335	large ribosomal subunit rRNA binding
INE82_RS17540	COG1940	carbohydrate kinase activity
INE82_RS17545	COG0577	efflux transmembrane transporter activity
INE82_RS17545	COG1136	(ABC) transporter
INE82_RS17550	COG0577	efflux transmembrane transporter activity
INE82_RS17550	COG1136	(ABC) transporter
INE82_RS17555	COG0577	efflux transmembrane transporter activity
INE82_RS17555	COG1136	(ABC) transporter
INE82_RS17560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS17565	COG1538	Outer membrane efflux protein
INE82_RS17570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INE82_RS17570	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INE82_RS17580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INE82_RS17600	COG2996	Protein conserved in bacteria
INE82_RS17605	COG0039	L-malate dehydrogenase activity
INE82_RS17615	COG2217	Heavy metal translocating P-type atpase
INE82_RS17625	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
INE82_RS17630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
INE82_RS17635	COG0509	glycine decarboxylation via glycine cleavage system
INE82_RS17650	COG0514	ATP-dependent DNA helicase (RecQ)
INE82_RS17665	COG0006	proline dipeptidase activity
INE82_RS17670	COG3250	beta-galactosidase activity
INE82_RS17675	COG3408	Glycogen debranching enzyme
INE82_RS17680	COG3458	cephalosporin-C deacetylase activity
INE82_RS17695	COG1283	sodium-dependent phosphate transmembrane transporter activity
INE82_RS17710	COG4206	TonB-dependent receptor
INE82_RS17710	COG1629	transport
INE82_RS17740	COG1773	rubredoxin
INE82_RS17745	COG2202	Pas domain
INE82_RS17745	COG2205	protein histidine kinase activity
INE82_RS17750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INE82_RS17755	COG1011	Hydrolase
INE82_RS17760	COG0196	riboflavin kinase activity
INE82_RS17765	COG1266	CAAX protease self-immunity
INE82_RS17775	COG3655	Transcriptional regulator
INE82_RS17780	COG2166	iron-sulfur cluster assembly
INE82_RS17785	COG2234	aminopeptidase activity
INE82_RS17790	COG1619	proteins homologs of microcin C7 resistance protein MccF
INE82_RS17800	COG0280	phosphate acetyltransferase
INE82_RS17805	COG3426	butyrate kinase activity
INE82_RS17830	COG4206	TonB-dependent receptor
INE82_RS17830	COG1629	transport
INE82_RS17845	COG1185	polyribonucleotide nucleotidyltransferase activity
INE82_RS17855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INE82_RS17875	COG1595	DNA-templated transcription, initiation
INE82_RS17880	COG0076	glutamate decarboxylase activity
INE82_RS17885	COG2066	Belongs to the glutaminase family
INE82_RS17895	COG0531	amino acid
INE82_RS18040	COG0667	Aldo Keto reductase
INE82_RS18045	COG3250	beta-galactosidase activity
INE82_RS18075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS18085	COG1309	transcriptional regulator
INE82_RS18090	COG2986	histidine ammonia-lyase
INE82_RS18100	COG1228	amidohydrolase
INE82_RS18110	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
INE82_RS18120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE82_RS18135	COG0203	ribosomal protein L17
INE82_RS18140	COG0202	RNA polymerase activity
INE82_RS18145	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
INE82_RS18150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
INE82_RS18155	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
INE82_RS18160	COG0257	Belongs to the bacterial ribosomal protein bL36 family
INE82_RS18165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
INE82_RS18180	COG0200	Binds to the 23S rRNA
INE82_RS18185	COG1841	ribosomal large subunit assembly
INE82_RS18190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
INE82_RS18195	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
INE82_RS18200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
INE82_RS18205	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
INE82_RS18210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
INE82_RS18215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
INE82_RS18220	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
INE82_RS18225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
INE82_RS18230	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
INE82_RS18235	COG0255	Belongs to the universal ribosomal protein uL29 family
INE82_RS18240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
INE82_RS18245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
INE82_RS18250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
INE82_RS18255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
INE82_RS18260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
INE82_RS18265	COG0089	rRNA binding
INE82_RS18270	COG0088	Forms part of the polypeptide exit tunnel
INE82_RS18275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
INE82_RS18280	COG0051	transcription antitermination factor activity, RNA binding
INE82_RS18285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INE82_RS18290	COG0049	tRNA binding
INE82_RS18295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
INE82_RS18305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
INE82_RS18310	COG0085	RNA polymerase activity
INE82_RS18315	COG0222	ribosome binding
INE82_RS18320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
INE82_RS18325	COG0081	regulation of translation
INE82_RS18330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
INE82_RS18340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INE82_RS18350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
INE82_RS18380	COG4974	Belongs to the 'phage' integrase family
INE82_RS18385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
INE82_RS18390	COG0006	proline dipeptidase activity
INE82_RS18395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
INE82_RS18405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INE82_RS18415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
INE82_RS18425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INE82_RS18440	COG1595	DNA-templated transcription, initiation
INE82_RS18455	COG1027	Aspartate ammonia-lyase
INE82_RS18460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INE82_RS18465	COG0252	asparaginase activity
INE82_RS18480	COG2096	Adenosyltransferase
INE82_RS18515	COG2815	serine threonine protein kinase
INE82_RS18515	COG0515	serine threonine protein kinase
INE82_RS18530	COG0631	protein serine/threonine phosphatase activity
INE82_RS18540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE82_RS18575	COG4974	Belongs to the 'phage' integrase family
INE82_RS18580	COG4804	nuclease activity
INE82_RS18665	COG0358	DNA primase activity
INE82_RS18685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INE82_RS18700	COG0662	Cupin 2, conserved barrel domain protein
INE82_RS18700	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
INE82_RS18705	COG0318	PFAM AMP-dependent synthetase and ligase
INE82_RS18710	COG1396	sequence-specific DNA binding
INE82_RS18725	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
INE82_RS18740	COG2059	Chromate
INE82_RS18745	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
INE82_RS18750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
INE82_RS18780	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
INE82_RS18785	COG4999	Histidine kinase
INE82_RS18785	COG3850	Histidine kinase
INE82_RS18785	COG3437	response regulator, receiver
INE82_RS18785	COG2205	protein histidine kinase activity
INE82_RS18790	COG0793	Belongs to the peptidase S41A family
INE82_RS18795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE82_RS18815	COG0483	inositol monophosphate 1-phosphatase activity
INE82_RS18825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE82_RS18830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE82_RS18835	COG1629	transport
INE82_RS18835	COG4206	TonB-dependent receptor
INE82_RS18865	COG3634	alkyl hydroperoxide reductase activity
INE82_RS18875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE82_RS18880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INE82_RS18885	COG2816	NAD+ diphosphatase activity
INE82_RS18900	COG1629	transport
INE82_RS18900	COG4206	TonB-dependent receptor
INE82_RS18940	COG0745	RESPONSE REGULATOR receiver
INE82_RS18940	COG3292	Two component regulator propeller
INE82_RS18940	COG2205	protein histidine kinase activity
INE82_RS18955	COG0018	arginyl-trna synthetase
INE82_RS18965	COG0705	Rhomboid family
INE82_RS18980	COG0339	signal peptide processing
INE82_RS18985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INE82_RS18995	COG0674	pyruvate-flavodoxin oxidoreductase activity
INE82_RS18995	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INE82_RS19000	COG1013	pyruvate-flavodoxin oxidoreductase activity
INE82_RS19005	COG4591	ABC-type transport system involved in lipoprotein release permease component
INE82_RS19010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
INE82_RS19030	COG4974	Belongs to the 'phage' integrase family
INE82_RS19045	COG0606	chelatase, subunit chli
INE82_RS19070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INE82_RS19110	COG0546	phosphoglycolate phosphatase activity
INE82_RS19150	COG0606	chelatase, subunit chli
INE82_RS19170	COG2205	protein histidine kinase activity
INE82_RS19180	COG3250	beta-galactosidase activity
INE82_RS19205	COG3634	alkyl hydroperoxide reductase activity
INE82_RS19210	COG3250	beta-galactosidase activity
INE82_RS19235	COG0702	epimerase
INE82_RS19240	COG4771	TonB-dependent receptor
INE82_RS19250	COG3507	Belongs to the glycosyl hydrolase 43 family
INE82_RS19255	COG3408	Glycogen debranching enzyme
INE82_RS19255	COG3119	arylsulfatase activity
INE82_RS19275	COG3119	arylsulfatase activity
INE82_RS19280	COG2017	converts alpha-aldose to the beta-anomer
INE82_RS19285	COG0702	epimerase
INE82_RS19290	COG4206	TonB-dependent receptor
INE82_RS19290	COG1629	transport
INE82_RS19340	COG0673	inositol 2-dehydrogenase activity
INE82_RS19350	COG0673	inositol 2-dehydrogenase activity
INE82_RS19355	COG0745	RESPONSE REGULATOR receiver
INE82_RS19355	COG2205	protein histidine kinase activity
INE82_RS19355	COG3292	Two component regulator propeller
INE82_RS19425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE82_RS19425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE82_RS19445	COG0438	transferase activity, transferring glycosyl groups
INE82_RS19455	COG0438	transferase activity, transferring glycosyl groups
INE82_RS19485	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
INE82_RS19490	COG0438	transferase activity, transferring glycosyl groups
INE82_RS19495	COG1216	Glycosyl transferase, family 2
INE82_RS19520	COG5492	domain, Protein
INE82_RS19535	COG0702	epimerase
INE82_RS19540	COG4771	TonB-dependent receptor
INE82_RS19545	COG3250	beta-galactosidase activity
INE82_RS19555	COG2205	protein histidine kinase activity
INE82_RS19555	COG2205	protein histidine kinase activity
INE82_RS19555	COG0745	RESPONSE REGULATOR receiver
INE82_RS19555	COG0745	RESPONSE REGULATOR receiver
INE82_RS19555	COG3292	Two component regulator propeller
INE82_RS19555	COG3292	Two component regulator propeller
INE82_RS19575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
INE82_RS19580	COG0545	Peptidyl-prolyl cis-trans isomerase
INE82_RS19585	COG0545	Peptidyl-prolyl cis-trans isomerase
INE82_RS19630	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS19645	COG1629	transport
INE82_RS19650	COG0561	phosphatase activity
INE82_RS19705	COG4771	TonB-dependent receptor
INE82_RS19725	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE82_RS19730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE82_RS19750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
INE82_RS19755	COG3409	Peptidoglycan-binding domain 1 protein
INE82_RS19755	COG0793	Belongs to the peptidase S41A family
INE82_RS19800	COG1082	Xylose isomerase domain protein TIM barrel
INE82_RS19815	COG1629	transport
INE82_RS19820	COG3292	Two component regulator propeller
INE82_RS19820	COG2205	protein histidine kinase activity
INE82_RS19820	COG0745	RESPONSE REGULATOR receiver
INE82_RS19840	COG4771	TonB-dependent receptor
INE82_RS19860	COG3119	arylsulfatase activity
INE82_RS19865	COG3119	arylsulfatase activity
INE82_RS19870	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE82_RS19875	COG3119	arylsulfatase activity
INE82_RS19890	COG1053	succinate dehydrogenase
INE82_RS19895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
INE82_RS19900	COG3119	arylsulfatase activity
INE82_RS19945	COG4771	TonB-dependent receptor
INE82_RS19950	COG0702	epimerase
INE82_RS19960	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS19980	COG0758	DNA mediated transformation
INE82_RS19980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
INE82_RS19990	COG0826	peptidase U32
INE82_RS20000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INE82_RS20015	COG0557	exoribonuclease II activity
INE82_RS20035	COG1629	transport
INE82_RS20035	COG4206	TonB-dependent receptor
INE82_RS20040	COG0561	phosphatase activity
INE82_RS20050	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS20060	COG1917	Cupin 2, conserved barrel domain protein
INE82_RS20065	COG1621	beta-fructofuranosidase activity
INE82_RS20080	COG1501	Belongs to the glycosyl hydrolase 31 family
INE82_RS20100	COG0702	epimerase
INE82_RS20105	COG4771	TonB-dependent receptor
INE82_RS20130	COG3408	Glycogen debranching enzyme
INE82_RS20130	COG3119	arylsulfatase activity
INE82_RS20140	COG3292	Two component regulator propeller
INE82_RS20140	COG2205	protein histidine kinase activity
INE82_RS20140	COG0745	RESPONSE REGULATOR receiver
INE82_RS20145	COG3119	arylsulfatase activity
INE82_RS20155	COG4771	TonB-dependent receptor
INE82_RS20180	COG3119	arylsulfatase activity
INE82_RS20195	COG1073	alpha beta
INE82_RS20200	COG2814	Major facilitator Superfamily
INE82_RS20205	COG0012	GTP binding
INE82_RS20210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
INE82_RS20215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
INE82_RS20230	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE82_RS20235	COG2207	Transcriptional regulator
INE82_RS20235	COG0662	Cupin 2, conserved barrel domain protein
INE82_RS20240	COG0697	spore germination
INE82_RS20250	COG0495	leucyl-tRNA aminoacylation
INE82_RS20255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INE82_RS20260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
INE82_RS20265	COG1360	Flagellar Motor Protein
INE82_RS20270	COG3537	Alpha-1,2-mannosidase
INE82_RS20290	COG0745	RESPONSE REGULATOR receiver
INE82_RS20290	COG3292	Two component regulator propeller
INE82_RS20290	COG2205	protein histidine kinase activity
INE82_RS20290	COG3292	Two component regulator propeller
INE82_RS20290	COG2205	protein histidine kinase activity
INE82_RS20290	COG0745	RESPONSE REGULATOR receiver
INE82_RS20310	COG4771	TonB-dependent receptor
INE82_RS20315	COG0702	epimerase
INE82_RS20325	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS20335	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS20340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
INE82_RS20360	COG0731	radical SAM domain protein
INE82_RS20360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INE82_RS20370	COG3119	arylsulfatase activity
INE82_RS20395	COG0659	secondary active sulfate transmembrane transporter activity
INE82_RS20400	COG1592	Rubrerythrin
INE82_RS20455	COG0427	acetyl-CoA hydrolase
INE82_RS20465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE82_RS20490	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE82_RS20540	COG2177	Part of the ABC transporter FtsEX involved in
INE82_RS20550	COG1968	undecaprenyl-diphosphatase activity
INE82_RS20555	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
INE82_RS20560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INE82_RS20570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
INE82_RS20585	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
INE82_RS20625	COG0594	ribonuclease P activity
INE82_RS20630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
INE82_RS20640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
INE82_RS20650	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
INE82_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
INE82_RS20695	COG1629	transport
INE82_RS20695	COG4206	TonB-dependent receptor
INE82_RS20720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INE82_RS20735	COG1121	(ABC) transporter
INE82_RS20745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
INE82_RS20745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INE82_RS20750	COG1238	metal cluster binding
INE82_RS20765	COG0823	Involved in the tonB-independent uptake of proteins
INE82_RS20765	COG1506	peptidase
INE82_RS20770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INE82_RS20770	COG0116	Belongs to the methyltransferase superfamily
INE82_RS20775	COG1045	serine acetyltransferase
INE82_RS20780	COG3275	phosphorelay sensor kinase activity
INE82_RS20785	COG3279	Response regulator of the LytR AlgR family
INE82_RS20795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INE82_RS20795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INE82_RS20800	COG0142	geranyltranstransferase activity
INE82_RS20815	COG1694	Mazg nucleotide pyrophosphohydrolase
INE82_RS20820	COG1490	D-aminoacyl-tRNA deacylase activity
INE82_RS20825	COG0322	excinuclease ABC activity
INE82_RS20830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INE82_RS20835	COG0445	tRNA wobble uridine modification
INE82_RS20850	COG4771	TonB-dependent receptor
INE82_RS20905	COG2197	response regulator
INE82_RS20915	COG4206	TonB-dependent receptor
INE82_RS20915	COG1629	transport
INE82_RS20935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
INE82_RS20940	COG0700	Nucleoside recognition
INE82_RS20945	COG2255	four-way junction helicase activity
INE82_RS20965	COG3591	Belongs to the peptidase S1B family
INE82_RS20970	COG3250	beta-galactosidase activity
INE82_RS20995	COG0582	viral genome integration into host DNA
INE82_RS21010	COG0582	viral genome integration into host DNA
INE82_RS21015	COG3250	beta-galactosidase activity
INE82_RS21020	COG4948	Mandelate Racemase Muconate Lactonizing
INE82_RS21040	COG0702	epimerase
INE82_RS21045	COG4771	TonB-dependent receptor
INE82_RS21065	COG3292	Two component regulator propeller
INE82_RS21065	COG2205	protein histidine kinase activity
INE82_RS21065	COG0745	RESPONSE REGULATOR receiver
INE82_RS21070	COG0513	Belongs to the DEAD box helicase family
INE82_RS21095	COG0612	Peptidase, M16
INE82_RS21105	COG4771	TonB-dependent receptor
INE82_RS21110	COG0702	epimerase
INE82_RS21125	COG1472	Belongs to the glycosyl hydrolase 3 family
INE82_RS21135	COG0681	Belongs to the peptidase S26 family
INE82_RS21145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
INE82_RS21155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE82_RS21180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INE82_RS21205	COG4771	TonB-dependent receptor
INE82_RS21210	COG3119	arylsulfatase activity
INE82_RS21215	COG0745	RESPONSE REGULATOR receiver
INE82_RS21215	COG2205	protein histidine kinase activity
INE82_RS21215	COG3292	Two component regulator propeller
INE82_RS21215	COG0745	RESPONSE REGULATOR receiver
INE82_RS21215	COG2205	protein histidine kinase activity
INE82_RS21215	COG3292	Two component regulator propeller
INE82_RS21225	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE82_RS21230	COG1538	Outer membrane efflux protein
INE82_RS21240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE82_RS21245	COG3250	beta-galactosidase activity
INE82_RS21275	COG4771	TonB-dependent receptor
INE82_RS21285	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE82_RS21290	COG3119	arylsulfatase activity
INE82_RS21295	COG5492	domain, Protein
INE82_RS21300	COG0215	cysteine-tRNA ligase activity
INE82_RS21305	COG0561	phosphatase activity
INE82_RS21310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
INE82_RS21315	COG0482	sulfurtransferase activity
INE82_RS21325	COG0205	6-phosphofructokinase activity
INE82_RS21330	COG0571	ribonuclease III activity
INE82_RS21335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INE82_RS21340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INE82_RS21350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INE82_RS21380	COG1442	glycosyl transferase family 8
INE82_RS21380	COG1216	Glycosyl transferase, family 2
INE82_RS21400	COG1215	transferase activity, transferring glycosyl groups
INE82_RS21405	COG1216	Glycosyl transferase, family 2
INE82_RS21420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
INE82_RS21425	COG0436	Aminotransferase
INE82_RS21445	COG0463	Glycosyl transferase, family 2
INE82_RS21475	COG1132	(ABC) transporter
INE82_RS21500	COG0328	RNA-DNA hybrid ribonuclease activity
INE82_RS21500	COG3341	Caulimovirus viroplasmin
INE82_RS21510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
INE82_RS21515	COG1166	arginine decarboxylase activity
INE82_RS21520	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
INE82_RS21525	COG1595	DNA-templated transcription, initiation
INE82_RS21555	COG0779	Required for maturation of 30S ribosomal subunits
INE82_RS21560	COG0195	Participates in both transcription termination and antitermination
INE82_RS21565	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
INE82_RS21575	COG0719	Fe-S assembly protein
INE82_RS21580	COG0396	ATPase activity
INE82_RS21585	COG0719	Fe-S assembly protein
INE82_RS21590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INE82_RS21595	COG0393	Putative heavy-metal-binding
INE82_RS21610	COG3292	Two component regulator propeller
INE82_RS21610	COG2205	protein histidine kinase activity
INE82_RS21610	COG0745	RESPONSE REGULATOR receiver
INE82_RS21610	COG3292	Two component regulator propeller
INE82_RS21610	COG2205	protein histidine kinase activity
INE82_RS21610	COG0745	RESPONSE REGULATOR receiver
INE82_RS21610	COG3292	Two component regulator propeller
INE82_RS21610	COG2205	protein histidine kinase activity
INE82_RS21610	COG0745	RESPONSE REGULATOR receiver
INE82_RS21615	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
INE82_RS21620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
INE82_RS21640	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
INE82_RS21655	COG0187	DNA topoisomerase II activity
INE82_RS21660	COG0268	Binds directly to 16S ribosomal RNA
INE82_RS21675	COG1381	Involved in DNA repair and RecF pathway recombination
INE82_RS21730	COG1610	YqeY-like protein
INE82_RS21735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INE82_RS21750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
INE82_RS21755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
INE82_RS21760	COG0772	Belongs to the SEDS family
INE82_RS21765	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
INE82_RS21775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INE82_RS21780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INE82_RS21795	COG0275	rRNA processing
INE82_RS21800	COG2001	Belongs to the MraZ family
INE82_RS21805	COG1595	DNA-templated transcription, initiation
INE82_RS21820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
INE82_RS21825	COG0756	dUTP diphosphatase activity
INE82_RS21840	COG4942	peptidase
INE82_RS21845	COG3292	Two component regulator propeller
INE82_RS21845	COG2205	protein histidine kinase activity
INE82_RS21845	COG0745	RESPONSE REGULATOR receiver
INE82_RS21865	COG4771	TonB-dependent receptor
INE82_RS21905	COG0702	epimerase
INE82_RS21910	COG4771	TonB-dependent receptor
INE82_RS21945	COG3119	arylsulfatase activity
INE82_RS21960	COG1629	transport