locus-tag	class	description
FE838_RS00010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FE838_RS00015	COG3177	Filamentation induced by cAMP protein fic
FE838_RS00115	COG0741	lytic transglycosylase activity
FE838_RS00115	COG1196	nuclear chromosome segregation
FE838_RS00115	COG0739	heme binding
FE838_RS00185	COG1192	Involved in chromosome partitioning
FE838_RS00195	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FE838_RS00200	COG0778	Nitroreductase
FE838_RS00210	COG1640	4-alpha-glucanotransferase
FE838_RS00225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FE838_RS00245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE838_RS00250	COG0318	PFAM AMP-dependent synthetase and ligase
FE838_RS00285	COG0359	binds to the 23S rRNA
FE838_RS00290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FE838_RS00295	COG0360	Binds together with S18 to 16S ribosomal RNA
FE838_RS00320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE838_RS00325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE838_RS00355	COG1131	(ABC) transporter
FE838_RS00365	COG2431	L-lysine efflux transmembrane transporter activity
FE838_RS00375	COG1193	negative regulation of DNA recombination
FE838_RS00410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE838_RS00425	COG2234	aminopeptidase activity
FE838_RS00450	COG0702	epimerase
FE838_RS00455	COG1629	transport
FE838_RS00470	COG3537	Alpha-1,2-mannosidase
FE838_RS00485	COG4206	TonB-dependent receptor
FE838_RS00485	COG1629	transport
FE838_RS00505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE838_RS00510	COG0802	atpase or kinase
FE838_RS00535	COG0714	Associated with various cellular activities
FE838_RS00585	COG3385	transposase activity
FE838_RS00620	COG3118	belongs to the thioredoxin family
FE838_RS00630	COG0688	phosphatidylethanolamine metabolic process
FE838_RS00635	COG1183	phosphatidylcholine synthase activity
FE838_RS00655	COG0792	nuclease activity
FE838_RS00680	COG0534	Mate efflux family protein
FE838_RS00685	COG0528	UMP kinase activity
FE838_RS00720	COG0233	cytoplasmic translational termination
FE838_RS00725	COG1162	GTPase activity
FE838_RS00735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE838_RS00755	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FE838_RS00755	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FE838_RS00765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE838_RS00775	COG1629	transport
FE838_RS00775	COG4206	TonB-dependent receptor
FE838_RS00795	COG1629	transport
FE838_RS00800	COG4974	Belongs to the 'phage' integrase family
FE838_RS00805	COG4771	TonB-dependent receptor
FE838_RS00815	COG2095	MarC family integral membrane protein
FE838_RS00830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FE838_RS00840	COG1435	thymidine kinase activity
FE838_RS00845	COG0628	permease
FE838_RS00855	COG4974	Belongs to the 'phage' integrase family
FE838_RS00960	COG3344	reverse transcriptase
FE838_RS01035	COG1475	DNA binding
FE838_RS01040	COG3969	phosphoadenosine phosphosulfate
FE838_RS01105	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE838_RS01105	COG0551	DNA topoisomerase type I activity
FE838_RS01225	COG2433	Pfam Transposase IS66
FE838_RS01240	COG2433	Pfam Transposase IS66
FE838_RS01275	COG1396	sequence-specific DNA binding
FE838_RS01285	COG4771	TonB-dependent receptor
FE838_RS01295	COG4771	TonB-dependent receptor
FE838_RS01330	COG0693	protein deglycase activity
FE838_RS01375	COG0300	oxidoreductase activity
FE838_RS01385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE838_RS01390	COG1595	DNA-templated transcription, initiation
FE838_RS01395	COG0110	maltose O-acetyltransferase activity
FE838_RS01405	COG1522	sequence-specific DNA binding
FE838_RS01430	COG0745	RESPONSE REGULATOR receiver
FE838_RS01430	COG3292	Two component regulator propeller
FE838_RS01430	COG2205	protein histidine kinase activity
FE838_RS01440	COG1629	transport
FE838_RS01475	COG2818	Glycosylase
FE838_RS01480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE838_RS01485	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FE838_RS01490	COG0527	aspartate kinase activity
FE838_RS01490	COG0460	homoserine dehydrogenase
FE838_RS01495	COG0252	asparaginase activity
FE838_RS01505	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FE838_RS01510	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FE838_RS01520	COG4771	TonB-dependent receptor
FE838_RS01540	COG0826	peptidase U32
FE838_RS01545	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FE838_RS01555	COG0436	Aminotransferase
FE838_RS01560	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE838_RS01580	COG0519	Catalyzes the synthesis of GMP from XMP
FE838_RS01585	COG5002	protein histidine kinase activity
FE838_RS01590	COG2205	protein histidine kinase activity
FE838_RS01600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FE838_RS01610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE838_RS01675	COG3250	beta-galactosidase activity
FE838_RS01680	COG2204	response regulator
FE838_RS01685	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE838_RS01710	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS01715	COG0737	Belongs to the 5'-nucleotidase family
FE838_RS01720	COG0737	Belongs to the 5'-nucleotidase family
FE838_RS01740	COG4974	Belongs to the 'phage' integrase family
FE838_RS01795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE838_RS01800	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS01810	COG4771	TonB-dependent receptor
FE838_RS01870	COG1333	cytochrome c biogenesis protein
FE838_RS01870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE838_RS01950	COG0335	large ribosomal subunit rRNA binding
FE838_RS01965	COG1940	carbohydrate kinase activity
FE838_RS01970	COG0577	efflux transmembrane transporter activity
FE838_RS01970	COG1136	(ABC) transporter
FE838_RS01975	COG0577	efflux transmembrane transporter activity
FE838_RS01975	COG1136	(ABC) transporter
FE838_RS01980	COG1136	(ABC) transporter
FE838_RS01980	COG0577	efflux transmembrane transporter activity
FE838_RS01985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS01995	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE838_RS01995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FE838_RS02005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE838_RS02025	COG2996	Protein conserved in bacteria
FE838_RS02050	COG0039	L-malate dehydrogenase activity
FE838_RS02060	COG2217	Heavy metal translocating P-type atpase
FE838_RS02075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FE838_RS02080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FE838_RS02085	COG0509	glycine decarboxylation via glycine cleavage system
FE838_RS02100	COG0006	proline dipeptidase activity
FE838_RS02105	COG3250	beta-galactosidase activity
FE838_RS02110	COG3408	Glycogen debranching enzyme
FE838_RS02115	COG3458	cephalosporin-C deacetylase activity
FE838_RS02130	COG1283	sodium-dependent phosphate transmembrane transporter activity
FE838_RS02145	COG1629	transport
FE838_RS02145	COG4206	TonB-dependent receptor
FE838_RS02185	COG1773	rubredoxin
FE838_RS02195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FE838_RS02200	COG1011	Hydrolase
FE838_RS02205	COG0196	riboflavin kinase activity
FE838_RS02210	COG1266	CAAX protease self-immunity
FE838_RS02220	COG3655	Transcriptional regulator
FE838_RS02225	COG2166	iron-sulfur cluster assembly
FE838_RS02230	COG2234	aminopeptidase activity
FE838_RS02235	COG1619	proteins homologs of microcin C7 resistance protein MccF
FE838_RS02245	COG0280	phosphate acetyltransferase
FE838_RS02250	COG3426	butyrate kinase activity
FE838_RS02290	COG4206	TonB-dependent receptor
FE838_RS02290	COG1629	transport
FE838_RS02305	COG1185	polyribonucleotide nucleotidyltransferase activity
FE838_RS02315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE838_RS02335	COG1595	DNA-templated transcription, initiation
FE838_RS02340	COG0076	glutamate decarboxylase activity
FE838_RS02345	COG2066	Belongs to the glutaminase family
FE838_RS02355	COG0531	amino acid
FE838_RS02520	COG4804	nuclease activity
FE838_RS02570	COG3344	reverse transcriptase
FE838_RS02580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE838_RS02580	COG0784	Response regulator, receiver
FE838_RS02580	COG2198	Histidine kinase
FE838_RS02580	COG2205	protein histidine kinase activity
FE838_RS02585	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS02590	COG0657	acetylesterase activity
FE838_RS02590	COG2755	lipolytic protein G-D-S-L family
FE838_RS02595	COG3661	Belongs to the glycosyl hydrolase 67 family
FE838_RS02610	COG0702	epimerase
FE838_RS02615	COG4771	TonB-dependent receptor
FE838_RS02625	COG0745	RESPONSE REGULATOR receiver
FE838_RS02625	COG3292	Two component regulator propeller
FE838_RS02625	COG2205	protein histidine kinase activity
FE838_RS02630	COG3537	Alpha-1,2-mannosidase
FE838_RS02655	COG4974	Belongs to the 'phage' integrase family
FE838_RS02680	COG0551	DNA topoisomerase type I activity
FE838_RS02680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE838_RS02880	COG0667	Aldo Keto reductase
FE838_RS02885	COG3250	beta-galactosidase activity
FE838_RS02920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS02930	COG1309	transcriptional regulator
FE838_RS02935	COG2986	histidine ammonia-lyase
FE838_RS02945	COG1228	amidohydrolase
FE838_RS02955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FE838_RS02965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FE838_RS02980	COG0203	ribosomal protein L17
FE838_RS02985	COG0202	RNA polymerase activity
FE838_RS02990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FE838_RS02995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FE838_RS03000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FE838_RS03005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FE838_RS03010	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FE838_RS03025	COG0200	Binds to the 23S rRNA
FE838_RS03030	COG1841	ribosomal large subunit assembly
FE838_RS03035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FE838_RS03040	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FE838_RS03045	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FE838_RS03050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FE838_RS03055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FE838_RS03060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FE838_RS03065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FE838_RS03070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FE838_RS03075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE838_RS03080	COG0255	Belongs to the universal ribosomal protein uL29 family
FE838_RS03085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FE838_RS03090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FE838_RS03095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FE838_RS03100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FE838_RS03105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FE838_RS03110	COG0089	rRNA binding
FE838_RS03115	COG0088	Forms part of the polypeptide exit tunnel
FE838_RS03120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FE838_RS03125	COG0051	transcription antitermination factor activity, RNA binding
FE838_RS03130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FE838_RS03135	COG0049	tRNA binding
FE838_RS03140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FE838_RS03150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FE838_RS03155	COG0085	RNA polymerase activity
FE838_RS03160	COG0222	ribosome binding
FE838_RS03165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FE838_RS03170	COG0081	regulation of translation
FE838_RS03175	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FE838_RS03185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FE838_RS03195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FE838_RS03225	COG4974	Belongs to the 'phage' integrase family
FE838_RS03230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FE838_RS03235	COG0006	proline dipeptidase activity
FE838_RS03240	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FE838_RS03260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE838_RS03270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE838_RS03280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE838_RS03295	COG1027	Aspartate ammonia-lyase
FE838_RS03300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FE838_RS03305	COG0252	asparaginase activity
FE838_RS03320	COG2096	Adenosyltransferase
FE838_RS03335	COG3328	transposase activity
FE838_RS03365	COG2815	serine threonine protein kinase
FE838_RS03365	COG0515	serine threonine protein kinase
FE838_RS03380	COG0631	protein serine/threonine phosphatase activity
FE838_RS03390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE838_RS03430	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FE838_RS03430	COG0662	Cupin 2, conserved barrel domain protein
FE838_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
FE838_RS03440	COG1396	sequence-specific DNA binding
FE838_RS03455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FE838_RS03470	COG2059	Chromate
FE838_RS03475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FE838_RS03480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FE838_RS03510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FE838_RS03520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE838_RS03540	COG0483	inositol monophosphate 1-phosphatase activity
FE838_RS03550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE838_RS03555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE838_RS03560	COG4206	TonB-dependent receptor
FE838_RS03560	COG1629	transport
FE838_RS03590	COG3634	alkyl hydroperoxide reductase activity
FE838_RS03600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE838_RS03605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE838_RS03625	COG4206	TonB-dependent receptor
FE838_RS03625	COG1629	transport
FE838_RS03665	COG2205	protein histidine kinase activity
FE838_RS03665	COG3292	Two component regulator propeller
FE838_RS03665	COG0745	RESPONSE REGULATOR receiver
FE838_RS03665	COG2205	protein histidine kinase activity
FE838_RS03665	COG0745	RESPONSE REGULATOR receiver
FE838_RS03665	COG3292	Two component regulator propeller
FE838_RS03680	COG0018	arginyl-trna synthetase
FE838_RS03690	COG0705	Rhomboid family
FE838_RS03705	COG0339	signal peptide processing
FE838_RS03710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE838_RS03720	COG0674	pyruvate-flavodoxin oxidoreductase activity
FE838_RS03720	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FE838_RS03725	COG1013	pyruvate-flavodoxin oxidoreductase activity
FE838_RS03730	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE838_RS03735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FE838_RS03755	COG4974	Belongs to the 'phage' integrase family
FE838_RS03770	COG0606	chelatase, subunit chli
FE838_RS03790	COG2205	protein histidine kinase activity
FE838_RS03810	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS03815	COG3250	beta-galactosidase activity
FE838_RS03830	COG0561	phosphatase activity
FE838_RS03835	COG4206	TonB-dependent receptor
FE838_RS03835	COG1629	transport
FE838_RS03840	COG0745	RESPONSE REGULATOR receiver
FE838_RS03840	COG2205	protein histidine kinase activity
FE838_RS03840	COG0745	RESPONSE REGULATOR receiver
FE838_RS03840	COG3292	Two component regulator propeller
FE838_RS03840	COG3292	Two component regulator propeller
FE838_RS03840	COG2205	protein histidine kinase activity
FE838_RS03860	COG0438	transferase activity, transferring glycosyl groups
FE838_RS03865	COG0438	transferase activity, transferring glycosyl groups
FE838_RS03880	COG1215	transferase activity, transferring glycosyl groups
FE838_RS03885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FE838_RS03905	COG1442	glycosyl transferase family 8
FE838_RS03920	COG1442	glycosyl transferase family 8
FE838_RS03920	COG1216	Glycosyl transferase, family 2
FE838_RS03955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE838_RS03975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE838_RS03980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE838_RS04005	COG4771	TonB-dependent receptor
FE838_RS04020	COG2205	protein histidine kinase activity
FE838_RS04020	COG0745	RESPONSE REGULATOR receiver
FE838_RS04020	COG3292	Two component regulator propeller
FE838_RS04060	COG1629	transport
FE838_RS04095	COG3940	Belongs to the glycosyl hydrolase 43 family
FE838_RS04100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FE838_RS04105	COG3119	arylsulfatase activity
FE838_RS04130	COG0702	epimerase
FE838_RS04135	COG1629	transport
FE838_RS04135	COG4206	TonB-dependent receptor
FE838_RS04145	COG3250	beta-galactosidase activity
FE838_RS04150	COG2205	protein histidine kinase activity
FE838_RS04150	COG0745	RESPONSE REGULATOR receiver
FE838_RS04150	COG3292	Two component regulator propeller
FE838_RS04210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE838_RS04210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE838_RS04225	COG0438	transferase activity, transferring glycosyl groups
FE838_RS04235	COG0438	transferase activity, transferring glycosyl groups
FE838_RS04270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE838_RS04275	COG0438	transferase activity, transferring glycosyl groups
FE838_RS04280	COG1216	Glycosyl transferase, family 2
FE838_RS04285	COG2133	pyrroloquinoline quinone binding
FE838_RS04285	COG5183	chlorophyll binding
FE838_RS04305	COG1629	transport
FE838_RS04305	COG4206	TonB-dependent receptor
FE838_RS04320	COG1882	Formate acetyltransferase
FE838_RS04355	COG5492	domain, Protein
FE838_RS04370	COG0702	epimerase
FE838_RS04375	COG4771	TonB-dependent receptor
FE838_RS04380	COG3250	beta-galactosidase activity
FE838_RS04390	COG0745	RESPONSE REGULATOR receiver
FE838_RS04390	COG2205	protein histidine kinase activity
FE838_RS04390	COG0745	RESPONSE REGULATOR receiver
FE838_RS04390	COG3292	Two component regulator propeller
FE838_RS04390	COG2205	protein histidine kinase activity
FE838_RS04390	COG3292	Two component regulator propeller
FE838_RS04410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE838_RS04415	COG0545	Peptidyl-prolyl cis-trans isomerase
FE838_RS04420	COG0545	Peptidyl-prolyl cis-trans isomerase
FE838_RS04465	COG2003	Belongs to the UPF0758 family
FE838_RS04545	COG0210	DNA helicase
FE838_RS04600	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS04615	COG1629	transport
FE838_RS04620	COG0561	phosphatase activity
FE838_RS04670	COG4771	TonB-dependent receptor
FE838_RS04690	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FE838_RS04695	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE838_RS04720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FE838_RS04725	COG0793	Belongs to the peptidase S41A family
FE838_RS04725	COG3409	Peptidoglycan-binding domain 1 protein
FE838_RS04775	COG1629	transport
FE838_RS04790	COG3292	Two component regulator propeller
FE838_RS04790	COG2205	protein histidine kinase activity
FE838_RS04790	COG0745	RESPONSE REGULATOR receiver
FE838_RS04800	COG3119	arylsulfatase activity
FE838_RS04820	COG1053	succinate dehydrogenase
FE838_RS04825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE838_RS04835	COG3119	arylsulfatase activity
FE838_RS04870	COG3345	alpha-galactosidase
FE838_RS04895	COG0758	DNA mediated transformation
FE838_RS04895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE838_RS04905	COG0826	peptidase U32
FE838_RS04910	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE838_RS04925	COG0557	exoribonuclease II activity
FE838_RS04940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FE838_RS04945	COG1917	Cupin 2, conserved barrel domain protein
FE838_RS04950	COG1621	beta-fructofuranosidase activity
FE838_RS04965	COG1501	Belongs to the glycosyl hydrolase 31 family
FE838_RS04985	COG0702	epimerase
FE838_RS04990	COG4771	TonB-dependent receptor
FE838_RS05015	COG3119	arylsulfatase activity
FE838_RS05015	COG3408	Glycogen debranching enzyme
FE838_RS05025	COG0745	RESPONSE REGULATOR receiver
FE838_RS05025	COG3292	Two component regulator propeller
FE838_RS05025	COG2205	protein histidine kinase activity
FE838_RS05045	COG3119	arylsulfatase activity
FE838_RS05055	COG4771	TonB-dependent receptor
FE838_RS05080	COG3119	arylsulfatase activity
FE838_RS05095	COG1073	alpha beta
FE838_RS05100	COG2814	Major facilitator Superfamily
FE838_RS05110	COG1012	belongs to the aldehyde dehydrogenase family
FE838_RS05120	COG0012	GTP binding
FE838_RS05125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FE838_RS05130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FE838_RS05145	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FE838_RS05150	COG2207	Transcriptional regulator
FE838_RS05150	COG0662	Cupin 2, conserved barrel domain protein
FE838_RS05155	COG0697	spore germination
FE838_RS05165	COG0495	leucyl-tRNA aminoacylation
FE838_RS05170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FE838_RS05175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FE838_RS05180	COG1360	Flagellar Motor Protein
FE838_RS05185	COG3537	Alpha-1,2-mannosidase
FE838_RS05215	COG4974	Belongs to the 'phage' integrase family
FE838_RS05305	COG1629	transport
FE838_RS05325	COG5434	Belongs to the glycosyl hydrolase 28 family
FE838_RS05335	COG0584	glycerophosphoryl diester phosphodiesterase
FE838_RS05340	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS05345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE838_RS05365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE838_RS05365	COG0731	radical SAM domain protein
FE838_RS05385	COG0745	RESPONSE REGULATOR receiver
FE838_RS05385	COG0745	RESPONSE REGULATOR receiver
FE838_RS05385	COG2205	protein histidine kinase activity
FE838_RS05385	COG3292	Two component regulator propeller
FE838_RS05385	COG2205	protein histidine kinase activity
FE838_RS05385	COG3292	Two component regulator propeller
FE838_RS05395	COG1629	transport
FE838_RS05395	COG4206	TonB-dependent receptor
FE838_RS05410	COG3119	arylsulfatase activity
FE838_RS05415	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS05420	COG3250	beta-galactosidase activity
FE838_RS05430	COG0659	secondary active sulfate transmembrane transporter activity
FE838_RS05435	COG1592	Rubrerythrin
FE838_RS05460	COG2027	D-alanyl-D-alanine carboxypeptidase
FE838_RS05490	COG0427	acetyl-CoA hydrolase
FE838_RS05500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE838_RS05525	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS05575	COG2177	Part of the ABC transporter FtsEX involved in
FE838_RS05585	COG1968	undecaprenyl-diphosphatase activity
FE838_RS05590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE838_RS05595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE838_RS05605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE838_RS05620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FE838_RS05645	COG1611	Belongs to the LOG family
FE838_RS05660	COG0594	ribonuclease P activity
FE838_RS05665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FE838_RS05675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE838_RS05685	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FE838_RS05690	COG1028	Short-chain dehydrogenase reductase Sdr
FE838_RS05730	COG1629	transport
FE838_RS05730	COG4206	TonB-dependent receptor
FE838_RS05755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE838_RS05770	COG1121	(ABC) transporter
FE838_RS05780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE838_RS05780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE838_RS05800	COG0823	Involved in the tonB-independent uptake of proteins
FE838_RS05800	COG1506	peptidase
FE838_RS05805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE838_RS05805	COG0116	Belongs to the methyltransferase superfamily
FE838_RS05810	COG1045	serine acetyltransferase
FE838_RS05815	COG3275	phosphorelay sensor kinase activity
FE838_RS05820	COG3279	Response regulator of the LytR AlgR family
FE838_RS05830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE838_RS05830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FE838_RS05835	COG0142	geranyltranstransferase activity
FE838_RS05850	COG1694	Mazg nucleotide pyrophosphohydrolase
FE838_RS05855	COG1490	D-aminoacyl-tRNA deacylase activity
FE838_RS05860	COG0322	excinuclease ABC activity
FE838_RS05865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FE838_RS05870	COG0445	tRNA wobble uridine modification
FE838_RS05885	COG4771	TonB-dependent receptor
FE838_RS05915	COG2197	response regulator
FE838_RS05925	COG4206	TonB-dependent receptor
FE838_RS05925	COG1629	transport
FE838_RS05945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FE838_RS05950	COG0700	Nucleoside recognition
FE838_RS05955	COG2255	four-way junction helicase activity
FE838_RS05975	COG3591	Belongs to the peptidase S1B family
FE838_RS05990	COG3250	beta-galactosidase activity
FE838_RS05995	COG3250	beta-galactosidase activity
FE838_RS06000	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS06010	COG0702	epimerase
FE838_RS06015	COG4771	TonB-dependent receptor
FE838_RS06040	COG2205	protein histidine kinase activity
FE838_RS06040	COG0745	RESPONSE REGULATOR receiver
FE838_RS06040	COG3292	Two component regulator propeller
FE838_RS06045	COG0513	Belongs to the DEAD box helicase family
FE838_RS06070	COG0612	Peptidase, M16
FE838_RS06080	COG4771	TonB-dependent receptor
FE838_RS06085	COG0702	epimerase
FE838_RS06100	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS06115	COG0681	Belongs to the peptidase S26 family
FE838_RS06125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FE838_RS06135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE838_RS06145	COG5492	domain, Protein
FE838_RS06155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE838_RS06180	COG0702	epimerase
FE838_RS06185	COG4771	TonB-dependent receptor
FE838_RS06190	COG3119	arylsulfatase activity
FE838_RS06195	COG3292	Two component regulator propeller
FE838_RS06195	COG2205	protein histidine kinase activity
FE838_RS06195	COG0745	RESPONSE REGULATOR receiver
FE838_RS06195	COG3292	Two component regulator propeller
FE838_RS06195	COG2205	protein histidine kinase activity
FE838_RS06195	COG0745	RESPONSE REGULATOR receiver
FE838_RS06205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE838_RS06210	COG1538	Outer membrane efflux protein
FE838_RS06220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS06225	COG3250	beta-galactosidase activity
FE838_RS06250	COG0702	epimerase
FE838_RS06255	COG4771	TonB-dependent receptor
FE838_RS06265	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FE838_RS06270	COG3119	arylsulfatase activity
FE838_RS06275	COG5492	domain, Protein
FE838_RS06280	COG0215	cysteine-tRNA ligase activity
FE838_RS06285	COG0561	phosphatase activity
FE838_RS06290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE838_RS06295	COG0482	sulfurtransferase activity
FE838_RS06305	COG0205	6-phosphofructokinase activity
FE838_RS06310	COG0571	ribonuclease III activity
FE838_RS06315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE838_RS06320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE838_RS06330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE838_RS06360	COG1442	glycosyl transferase family 8
FE838_RS06360	COG1216	Glycosyl transferase, family 2
FE838_RS06380	COG1216	Glycosyl transferase, family 2
FE838_RS06380	COG1442	glycosyl transferase family 8
FE838_RS06385	COG1216	Glycosyl transferase, family 2
FE838_RS06400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE838_RS06405	COG0436	Aminotransferase
FE838_RS06425	COG0463	Glycosyl transferase, family 2
FE838_RS06455	COG1132	(ABC) transporter
FE838_RS06480	COG3341	Caulimovirus viroplasmin
FE838_RS06480	COG0328	RNA-DNA hybrid ribonuclease activity
FE838_RS06490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FE838_RS06495	COG1166	arginine decarboxylase activity
FE838_RS06500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FE838_RS06505	COG1595	DNA-templated transcription, initiation
FE838_RS06535	COG0779	Required for maturation of 30S ribosomal subunits
FE838_RS06540	COG0195	Participates in both transcription termination and antitermination
FE838_RS06545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FE838_RS06555	COG0719	Fe-S assembly protein
FE838_RS06560	COG0396	ATPase activity
FE838_RS06565	COG0719	Fe-S assembly protein
FE838_RS06570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE838_RS06575	COG0393	Putative heavy-metal-binding
FE838_RS06585	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FE838_RS06590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE838_RS06610	COG5433	transposase activity
FE838_RS06620	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FE838_RS06670	COG0187	DNA topoisomerase II activity
FE838_RS06675	COG0268	Binds directly to 16S ribosomal RNA
FE838_RS06690	COG1381	Involved in DNA repair and RecF pathway recombination
FE838_RS06745	COG1610	YqeY-like protein
FE838_RS06750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FE838_RS06765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE838_RS06770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FE838_RS06775	COG0772	Belongs to the SEDS family
FE838_RS06780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FE838_RS06790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE838_RS06795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE838_RS06810	COG0275	rRNA processing
FE838_RS06815	COG2001	Belongs to the MraZ family
FE838_RS06820	COG1595	DNA-templated transcription, initiation
FE838_RS06835	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FE838_RS06840	COG0756	dUTP diphosphatase activity
FE838_RS06855	COG4942	peptidase
FE838_RS06860	COG3292	Two component regulator propeller
FE838_RS06860	COG2205	protein histidine kinase activity
FE838_RS06860	COG0745	RESPONSE REGULATOR receiver
FE838_RS06880	COG0673	inositol 2-dehydrogenase activity
FE838_RS06885	COG0673	inositol 2-dehydrogenase activity
FE838_RS06895	COG0702	epimerase
FE838_RS06900	COG4771	TonB-dependent receptor
FE838_RS06945	COG0702	epimerase
FE838_RS06950	COG4771	TonB-dependent receptor
FE838_RS06985	COG1629	transport
FE838_RS07000	COG3119	arylsulfatase activity
FE838_RS07035	COG4771	TonB-dependent receptor
FE838_RS07040	COG0702	epimerase
FE838_RS07075	COG3250	beta-galactosidase activity
FE838_RS07090	COG3507	Belongs to the glycosyl hydrolase 43 family
FE838_RS07105	COG1629	transport
FE838_RS07110	COG0561	phosphatase activity
FE838_RS07145	COG3537	Alpha-1,2-mannosidase
FE838_RS07160	COG3537	Alpha-1,2-mannosidase
FE838_RS07170	COG2017	converts alpha-aldose to the beta-anomer
FE838_RS07235	COG1373	ATPase (AAA superfamily
FE838_RS07240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE838_RS07245	COG1022	Amp-dependent synthetase and ligase
FE838_RS07250	COG0612	Peptidase, M16
FE838_RS07265	COG2954	triphosphatase activity
FE838_RS07330	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS07340	COG4771	TonB-dependent receptor
FE838_RS07395	COG0673	inositol 2-dehydrogenase activity
FE838_RS07400	COG0673	inositol 2-dehydrogenase activity
FE838_RS07420	COG0363	glucosamine-6-phosphate deaminase activity
FE838_RS07425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE838_RS07445	COG3345	alpha-galactosidase
FE838_RS07475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS07490	COG0517	IMP dehydrogenase activity
FE838_RS07490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FE838_RS07505	COG4771	TonB-dependent receptor
FE838_RS07515	COG2814	Major facilitator Superfamily
FE838_RS07525	COG3458	cephalosporin-C deacetylase activity
FE838_RS07530	COG1609	Transcriptional regulator
FE838_RS07530	COG2207	Transcriptional regulator
FE838_RS07540	COG0423	glycine-tRNA ligase activity
FE838_RS07550	COG1609	Transcriptional regulator
FE838_RS07565	COG0738	Major facilitator superfamily
FE838_RS07570	COG1063	alcohol dehydrogenase
FE838_RS07585	COG2211	Major facilitator Superfamily
FE838_RS07590	COG2247	cell wall binding repeat
FE838_RS07590	COG2385	sporulation resulting in formation of a cellular spore
FE838_RS07595	COG1215	transferase activity, transferring glycosyl groups
FE838_RS07600	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE838_RS07665	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FE838_RS07675	COG0589	response to stress
FE838_RS07675	COG0475	glutathione-regulated potassium exporter activity
FE838_RS07680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE838_RS07685	COG1136	(ABC) transporter
FE838_RS07695	COG0733	neurotransmitter:sodium symporter activity
FE838_RS07705	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE838_RS07710	COG0784	Response regulator, receiver
FE838_RS07710	COG5002	protein histidine kinase activity
FE838_RS07715	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE838_RS07720	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FE838_RS07725	COG0312	modulator of DNA gyrase
FE838_RS07730	COG0312	modulator of DNA gyrase
FE838_RS07735	COG1704	LemA family
FE838_RS07765	COG3507	Belongs to the glycosyl hydrolase 43 family
FE838_RS07775	COG1501	Belongs to the glycosyl hydrolase 31 family
FE838_RS07785	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS07805	COG1082	Xylose isomerase domain protein TIM barrel
FE838_RS07830	COG1629	transport
FE838_RS07830	COG4206	TonB-dependent receptor
FE838_RS07870	COG0745	RESPONSE REGULATOR receiver
FE838_RS07870	COG2205	protein histidine kinase activity
FE838_RS07870	COG3292	Two component regulator propeller
FE838_RS07880	COG1629	transport
FE838_RS07925	COG1346	cytolysis
FE838_RS07930	COG1380	Effector of murein hydrolase LrgA
FE838_RS07935	COG0280	phosphate acetyltransferase
FE838_RS07940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE838_RS07945	COG0463	Glycosyl transferase, family 2
FE838_RS07945	COG1216	Glycosyl transferase, family 2
FE838_RS07950	COG2003	Belongs to the UPF0758 family
FE838_RS07960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE838_RS07965	COG0366	Alpha amylase catalytic
FE838_RS07980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE838_RS07985	COG4206	TonB-dependent receptor
FE838_RS07985	COG1629	transport
FE838_RS07990	COG1082	Xylose isomerase domain protein TIM barrel
FE838_RS07995	COG0366	Alpha amylase catalytic
FE838_RS08015	COG1785	Belongs to the alkaline phosphatase family
FE838_RS08020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FE838_RS08025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FE838_RS08030	COG0515	serine threonine protein kinase
FE838_RS08030	COG2815	serine threonine protein kinase
FE838_RS08035	COG0564	pseudouridine synthase activity
FE838_RS08040	COG1181	Belongs to the D-alanine--D-alanine ligase family
FE838_RS08060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FE838_RS08065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FE838_RS08070	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FE838_RS08075	COG0436	Aminotransferase
FE838_RS08085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FE838_RS08100	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE838_RS08105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE838_RS08115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE838_RS08115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE838_RS08120	COG2890	protein-(glutamine-N5) methyltransferase activity
FE838_RS08130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FE838_RS08140	COG0165	Argininosuccinate lyase
FE838_RS08155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE838_RS08175	COG0745	RESPONSE REGULATOR receiver
FE838_RS08175	COG3292	Two component regulator propeller
FE838_RS08175	COG2205	protein histidine kinase activity
FE838_RS08175	COG3292	Two component regulator propeller
FE838_RS08175	COG2205	protein histidine kinase activity
FE838_RS08175	COG0745	RESPONSE REGULATOR receiver
FE838_RS08180	COG0471	metal ion transport
FE838_RS08235	COG4771	TonB-dependent receptor
FE838_RS08255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE838_RS08260	COG1396	sequence-specific DNA binding
FE838_RS08260	COG1917	Cupin 2, conserved barrel domain protein
FE838_RS08265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FE838_RS08270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE838_RS08275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FE838_RS08280	COG0137	argininosuccinate synthase activity
FE838_RS08290	COG1438	arginine binding
FE838_RS08295	COG1070	Carbohydrate kinase
FE838_RS08300	COG4806	L-rhamnose isomerase
FE838_RS08310	COG0235	Class ii aldolase
FE838_RS08315	COG1454	alcohol dehydrogenase
FE838_RS08345	COG0564	pseudouridine synthase activity
FE838_RS08405	COG3537	Alpha-1,2-mannosidase
FE838_RS08410	COG0745	RESPONSE REGULATOR receiver
FE838_RS08410	COG2205	protein histidine kinase activity
FE838_RS08410	COG3292	Two component regulator propeller
FE838_RS08420	COG4206	TonB-dependent receptor
FE838_RS08420	COG1629	transport
FE838_RS08425	COG0702	epimerase
FE838_RS08460	COG3119	arylsulfatase activity
FE838_RS08475	COG3119	arylsulfatase activity
FE838_RS08480	COG3292	Two component regulator propeller
FE838_RS08480	COG0745	RESPONSE REGULATOR receiver
FE838_RS08480	COG2205	protein histidine kinase activity
FE838_RS08485	COG2204	response regulator
FE838_RS08490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE838_RS08495	COG0612	Peptidase, M16
FE838_RS08500	COG0534	Mate efflux family protein
FE838_RS08505	COG2205	protein histidine kinase activity
FE838_RS08505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE838_RS08530	COG0488	(ABC) transporter
FE838_RS08535	COG3590	peptidase
FE838_RS08540	COG0138	bifunctional purine biosynthesis protein purh
FE838_RS08565	COG0772	Belongs to the SEDS family
FE838_RS08575	COG1774	PSP1 C-terminal conserved region
FE838_RS08580	COG0470	DNA polymerase III
FE838_RS08585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FE838_RS08595	COG2193	ferroxidase activity
FE838_RS08675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE838_RS08680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FE838_RS08685	COG1160	GTP binding
FE838_RS08695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE838_RS08700	COG1127	ABC transporter
FE838_RS08705	COG0724	RNA recognition motif
FE838_RS08710	COG0544	peptidyl-prolyl cis-trans isomerase activity
FE838_RS08715	COG0740	serine-type endopeptidase activity
FE838_RS08720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FE838_RS08725	COG0514	ATP-dependent DNA helicase (RecQ)
FE838_RS08730	COG0516	GMP reductase activity
FE838_RS08730	COG0517	IMP dehydrogenase activity
FE838_RS08735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE838_RS08745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE838_RS08760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE838_RS08775	COG4771	TonB-dependent receptor
FE838_RS08795	COG3537	Alpha-1,2-mannosidase
FE838_RS08830	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE838_RS08840	COG3022	response to hydroperoxide
FE838_RS08845	COG0110	maltose O-acetyltransferase activity
FE838_RS08865	COG1187	pseudouridine synthase activity
FE838_RS08870	COG0017	Asparaginyl-tRNA synthetase
FE838_RS08880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FE838_RS08885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE838_RS08890	COG0052	Belongs to the universal ribosomal protein uS2 family
FE838_RS08895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FE838_RS08910	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FE838_RS08915	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE838_RS08920	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FE838_RS08935	COG0482	sulfurtransferase activity
FE838_RS08945	COG1570	exodeoxyribonuclease VII activity
FE838_RS08955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE838_RS08965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FE838_RS08970	COG0489	protein tyrosine kinase activity
FE838_RS08980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE838_RS09015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS09035	COG0714	Associated with various cellular activities
FE838_RS09040	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FE838_RS09045	COG3552	Protein containing von Willebrand factor type A (VWA) domain
FE838_RS09050	COG0039	L-malate dehydrogenase activity
FE838_RS09080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE838_RS09085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE838_RS09090	COG0811	peptide transport
FE838_RS09095	COG0848	biopolymer transport protein
FE838_RS09110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FE838_RS09115	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE838_RS09120	COG0105	UTP biosynthetic process
FE838_RS09125	COG0739	heme binding
FE838_RS09140	COG0149	triose-phosphate isomerase activity
FE838_RS09150	COG0302	gtp cyclohydrolase
FE838_RS09155	COG0358	DNA primase activity
FE838_RS09165	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FE838_RS09170	COG0436	Aminotransferase
FE838_RS09185	COG0514	ATP-dependent DNA helicase (RecQ)
FE838_RS09190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE838_RS09190	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FE838_RS09205	COG0009	L-threonylcarbamoyladenylate synthase
FE838_RS09215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FE838_RS09220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE838_RS09225	COG0658	competence protein
FE838_RS09225	COG2333	competence protein COMEC
FE838_RS09230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FE838_RS09240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE838_RS09250	COG4771	TonB-dependent receptor
FE838_RS09255	COG0561	phosphatase activity
FE838_RS09275	COG2205	protein histidine kinase activity
FE838_RS09275	COG0745	RESPONSE REGULATOR receiver
FE838_RS09275	COG3292	Two component regulator propeller
FE838_RS09280	COG4771	TonB-dependent receptor
FE838_RS09300	COG3537	Alpha-1,2-mannosidase
FE838_RS09305	COG3537	Alpha-1,2-mannosidase
FE838_RS09315	COG3537	Alpha-1,2-mannosidase
FE838_RS09320	COG3279	Response regulator of the LytR AlgR family
FE838_RS09325	COG3275	phosphorelay sensor kinase activity
FE838_RS09330	COG1566	PFAM secretion protein HlyD family protein
FE838_RS09345	COG0386	Belongs to the glutathione peroxidase family
FE838_RS09350	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FE838_RS09355	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FE838_RS09370	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FE838_RS09385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE838_RS09390	COG0742	ribosomal rna small subunit methyltransferase
FE838_RS09405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE838_RS09410	COG4771	TonB-dependent receptor
FE838_RS09445	COG3537	Alpha-1,2-mannosidase
FE838_RS09450	COG3537	Alpha-1,2-mannosidase
FE838_RS09470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE838_RS09475	COG0739	heme binding
FE838_RS09485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE838_RS09490	COG1388	LysM domain
FE838_RS09490	COG0741	lytic transglycosylase activity
FE838_RS09500	COG1475	DNA binding
FE838_RS09505	COG1192	Involved in chromosome partitioning
FE838_RS09510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE838_RS09515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE838_RS09525	COG4589	Belongs to the CDS family
FE838_RS09530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE838_RS09535	COG0799	negative regulation of ribosome biogenesis
FE838_RS09605	COG4974	Belongs to the 'phage' integrase family
FE838_RS09610	COG4974	Belongs to the 'phage' integrase family
FE838_RS09615	COG4974	Belongs to the 'phage' integrase family
FE838_RS09655	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS09690	COG0702	epimerase
FE838_RS09695	COG1629	transport
FE838_RS09695	COG4206	TonB-dependent receptor
FE838_RS09700	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS09700	COG3291	Pkd domain containing protein
FE838_RS09705	COG1196	nuclear chromosome segregation
FE838_RS09710	COG2239	Acts as a magnesium transporter
FE838_RS09715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE838_RS09725	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE838_RS09760	COG1119	ATPase activity
FE838_RS09770	COG0668	transmembrane transport
FE838_RS09775	COG2207	Transcriptional regulator
FE838_RS09775	COG0662	Cupin 2, conserved barrel domain protein
FE838_RS09800	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE838_RS09805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE838_RS09810	COG0713	ATP synthesis coupled electron transport
FE838_RS09825	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FE838_RS09830	COG0649	NAD binding
FE838_RS09830	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE838_RS09835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE838_RS09840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE838_RS09875	COG3250	beta-galactosidase activity
FE838_RS09885	COG3250	beta-galactosidase activity
FE838_RS09895	COG2755	lipolytic protein G-D-S-L family
FE838_RS09895	COG0657	acetylesterase activity
FE838_RS09910	COG1629	transport
FE838_RS09915	COG0702	epimerase
FE838_RS09930	COG0702	epimerase
FE838_RS09945	COG4771	TonB-dependent receptor
FE838_RS09950	COG0702	epimerase
FE838_RS09955	COG4206	TonB-dependent receptor
FE838_RS09955	COG1629	transport
FE838_RS09970	COG3537	Alpha-1,2-mannosidase
FE838_RS09990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE838_RS09995	COG0569	domain protein
FE838_RS10000	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FE838_RS10010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE838_RS10015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FE838_RS10020	COG0805	protein transport
FE838_RS10030	COG2271	Major facilitator Superfamily
FE838_RS10035	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FE838_RS10040	COG3775	system Galactitol-specific IIC component
FE838_RS10055	COG2755	lipolytic protein G-D-S-L family
FE838_RS10060	COG3292	Two component regulator propeller
FE838_RS10060	COG0745	RESPONSE REGULATOR receiver
FE838_RS10060	COG2205	protein histidine kinase activity
FE838_RS10070	COG0702	epimerase
FE838_RS10075	COG4771	TonB-dependent receptor
FE838_RS10095	COG3279	Response regulator of the LytR AlgR family
FE838_RS10110	COG4206	TonB-dependent receptor
FE838_RS10110	COG1629	transport
FE838_RS10125	COG2205	protein histidine kinase activity
FE838_RS10125	COG3292	Two component regulator propeller
FE838_RS10125	COG0745	RESPONSE REGULATOR receiver
FE838_RS10130	COG1242	4 iron, 4 sulfur cluster binding
FE838_RS10140	COG0363	glucosamine-6-phosphate deaminase activity
FE838_RS10145	COG0009	L-threonylcarbamoyladenylate synthase
FE838_RS10155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE838_RS10160	COG0561	phosphatase activity
FE838_RS10180	COG4771	TonB-dependent receptor
FE838_RS10190	COG0745	RESPONSE REGULATOR receiver
FE838_RS10190	COG3292	Two component regulator propeller
FE838_RS10190	COG2205	protein histidine kinase activity
FE838_RS10195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FE838_RS10200	COG1408	metallophosphoesterase
FE838_RS10220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE838_RS10250	COG2755	lipolytic protein G-D-S-L family
FE838_RS10280	COG3250	beta-galactosidase activity
FE838_RS10285	COG3345	alpha-galactosidase
FE838_RS10320	COG4771	TonB-dependent receptor
FE838_RS10325	COG0702	epimerase
FE838_RS10340	COG4771	TonB-dependent receptor
FE838_RS10365	COG2755	lipolytic protein G-D-S-L family
FE838_RS10375	COG3401	FG-GAP repeat protein
FE838_RS10385	COG3254	rhamnose metabolic process
FE838_RS10390	COG0745	RESPONSE REGULATOR receiver
FE838_RS10390	COG2205	protein histidine kinase activity
FE838_RS10390	COG3292	Two component regulator propeller
FE838_RS10390	COG0745	RESPONSE REGULATOR receiver
FE838_RS10390	COG3292	Two component regulator propeller
FE838_RS10390	COG2205	protein histidine kinase activity
FE838_RS10405	COG3250	beta-galactosidase activity
FE838_RS10410	COG0745	RESPONSE REGULATOR receiver
FE838_RS10410	COG2205	protein histidine kinase activity
FE838_RS10410	COG3292	Two component regulator propeller
FE838_RS10420	COG0546	phosphoglycolate phosphatase activity
FE838_RS10440	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FE838_RS10450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FE838_RS10460	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE838_RS10465	COG1506	peptidase
FE838_RS10465	COG0823	Involved in the tonB-independent uptake of proteins
FE838_RS10510	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE838_RS10525	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FE838_RS10525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FE838_RS10530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE838_RS10535	COG1078	dGTPase activity
FE838_RS10540	COG0284	orotidine-5'-phosphate decarboxylase activity
FE838_RS10545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FE838_RS10555	COG1704	LemA family
FE838_RS10570	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FE838_RS10575	COG2226	methyltransferase
FE838_RS10580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FE838_RS10585	COG1702	phosphate starvation-inducible protein PhoH
FE838_RS10595	COG2268	Band 7 protein
FE838_RS10685	COG3292	Two component regulator propeller
FE838_RS10685	COG0745	RESPONSE REGULATOR receiver
FE838_RS10685	COG2205	protein histidine kinase activity
FE838_RS10690	COG0101	tRNA pseudouridine synthase activity
FE838_RS10710	COG3250	beta-galactosidase activity
FE838_RS10715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FE838_RS10720	COG0673	inositol 2-dehydrogenase activity
FE838_RS10740	COG4771	TonB-dependent receptor
FE838_RS10760	COG5434	Belongs to the glycosyl hydrolase 28 family
FE838_RS10765	COG0673	inositol 2-dehydrogenase activity
FE838_RS10780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FE838_RS10790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FE838_RS10800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FE838_RS10805	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE838_RS10810	COG0793	Belongs to the peptidase S41A family
FE838_RS10815	COG2131	deaminase
FE838_RS10825	COG0339	signal peptide processing
FE838_RS10835	COG1970	mechanosensitive ion channel activity
FE838_RS10840	COG0519	Catalyzes the synthesis of GMP from XMP
FE838_RS10840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE838_RS10850	COG4771	TonB-dependent receptor
FE838_RS10920	COG0438	transferase activity, transferring glycosyl groups
FE838_RS10925	COG0463	Glycosyl transferase, family 2
FE838_RS11010	COG4771	TonB-dependent receptor
FE838_RS11040	COG0438	transferase activity, transferring glycosyl groups
FE838_RS11055	COG0297	glycogen (starch) synthase activity
FE838_RS11060	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FE838_RS11065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FE838_RS11070	COG0543	2 iron, 2 sulfur cluster binding
FE838_RS11080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FE838_RS11085	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FE838_RS11090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FE838_RS11105	COG0791	NLP P60 protein
FE838_RS11120	COG0612	Peptidase, M16
FE838_RS11125	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FE838_RS11130	COG1597	lipid kinase activity
FE838_RS11135	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FE838_RS11150	COG1136	(ABC) transporter
FE838_RS11170	COG2211	Major facilitator Superfamily
FE838_RS11175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FE838_RS11190	COG1674	ftsk spoiiie
FE838_RS11200	COG0492	ferredoxin-NADP+ reductase activity
FE838_RS11205	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS11235	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FE838_RS11235	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FE838_RS11245	COG1234	tRNA 3'-trailer cleavage
FE838_RS11265	COG3956	TIGRFAM MazG family protein
FE838_RS11280	COG0525	valine-tRNA ligase activity
FE838_RS11285	COG5002	protein histidine kinase activity
FE838_RS11285	COG2205	protein histidine kinase activity
FE838_RS11285	COG0784	Response regulator, receiver
FE838_RS11300	COG4206	TonB-dependent receptor
FE838_RS11300	COG1629	transport
FE838_RS11325	COG0653	protein targeting
FE838_RS11330	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FE838_RS11340	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FE838_RS11360	COG1253	flavin adenine dinucleotide binding
FE838_RS11370	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FE838_RS11380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FE838_RS11385	COG2204	response regulator
FE838_RS11425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE838_RS11425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE838_RS11435	COG3104	oligopeptide transport
FE838_RS11445	COG0563	adenylate kinase activity
FE838_RS11450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FE838_RS11475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS11480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS11490	COG2814	Major facilitator Superfamily
FE838_RS11495	COG0457	Tetratricopeptide repeat
FE838_RS11500	COG2706	6-phosphogluconolactonase activity
FE838_RS11525	COG4206	TonB-dependent receptor
FE838_RS11525	COG1629	transport
FE838_RS11590	COG3142	Participates in the control of copper homeostasis
FE838_RS11595	COG1418	mRNA catabolic process
FE838_RS11625	COG1070	Carbohydrate kinase
FE838_RS11630	COG1063	alcohol dehydrogenase
FE838_RS11635	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FE838_RS11660	COG1333	cytochrome c biogenesis protein
FE838_RS11660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE838_RS11695	COG3328	transposase activity
FE838_RS11755	COG0673	inositol 2-dehydrogenase activity
FE838_RS11765	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE838_RS11770	COG2832	Protein of unknown function (DUF454)
FE838_RS11780	COG0602	queuosine metabolic process
FE838_RS11785	COG0247	lactate metabolic process
FE838_RS11790	COG1139	Iron-sulfur cluster binding protein
FE838_RS11800	COG0351	phosphomethylpyrimidine kinase
FE838_RS11825	COG4589	Belongs to the CDS family
FE838_RS11835	COG2304	oxidoreductase activity
FE838_RS11850	COG1393	Belongs to the ArsC family
FE838_RS11860	COG4206	TonB-dependent receptor
FE838_RS11860	COG1629	transport
FE838_RS11875	COG2233	PERMEase
FE838_RS11880	COG1509	lysine 2,3-aminomutase activity
FE838_RS11890	COG1115	amino acid carrier protein
FE838_RS11940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE838_RS11945	COG1388	LysM domain
FE838_RS11945	COG0741	lytic transglycosylase activity
FE838_RS12005	COG0534	Mate efflux family protein
FE838_RS12015	COG0564	pseudouridine synthase activity
FE838_RS12040	COG0346	lactoylglutathione lyase activity
FE838_RS12100	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FE838_RS12105	COG4804	nuclease activity
FE838_RS12110	COG0732	type I restriction modification DNA specificity domain
FE838_RS12180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FE838_RS12185	COG3586	endonuclease activity
FE838_RS12200	COG3645	SOS response
FE838_RS12225	COG0582	viral genome integration into host DNA
FE838_RS12245	COG4974	Belongs to the 'phage' integrase family
FE838_RS12255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE838_RS12260	COG0784	Response regulator, receiver
FE838_RS12260	COG5002	protein histidine kinase activity
FE838_RS12265	COG2910	NAD(P)H-binding
FE838_RS12275	COG4864	UPF0365 protein
FE838_RS12290	COG0037	tRNA processing
FE838_RS12300	COG1477	protein flavinylation
FE838_RS12305	COG1971	Probably functions as a manganese efflux pump
FE838_RS12320	COG0463	Glycosyl transferase, family 2
FE838_RS12335	COG3279	Response regulator of the LytR AlgR family
FE838_RS12360	COG1595	DNA-templated transcription, initiation
FE838_RS12365	COG0148	phosphopyruvate hydratase activity
FE838_RS12375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FE838_RS12400	COG5433	transposase activity
FE838_RS12405	COG1082	Xylose isomerase domain protein TIM barrel
FE838_RS12410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FE838_RS12415	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE838_RS12420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FE838_RS12425	COG4651	solute:proton antiporter activity
FE838_RS12425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE838_RS12435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FE838_RS12440	COG0193	aminoacyl-tRNA hydrolase activity
FE838_RS12445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FE838_RS12455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FE838_RS12460	COG1862	Preprotein translocase
FE838_RS12470	COG0237	dephospho-CoA kinase activity
FE838_RS12485	COG0542	response to heat
FE838_RS12495	COG0583	DNA-binding transcription factor activity
FE838_RS12510	COG0443	Heat shock 70 kDa protein
FE838_RS12545	COG2855	membrane
FE838_RS12550	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE838_RS12555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE838_RS12575	COG0443	Heat shock 70 kDa protein
FE838_RS12640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FE838_RS12655	COG3119	arylsulfatase activity
FE838_RS12665	COG0702	epimerase
FE838_RS12670	COG4771	TonB-dependent receptor
FE838_RS12685	COG0306	phosphate transporter
FE838_RS12695	COG0586	Pfam SNARE associated Golgi protein
FE838_RS12745	COG0038	chloride channel
FE838_RS12750	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FE838_RS12765	COG1940	carbohydrate kinase activity
FE838_RS12775	COG3119	arylsulfatase activity
FE838_RS12785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FE838_RS12790	COG0702	epimerase
FE838_RS12795	COG4771	TonB-dependent receptor
FE838_RS12805	COG5434	Belongs to the glycosyl hydrolase 28 family
FE838_RS12810	COG0745	RESPONSE REGULATOR receiver
FE838_RS12810	COG3292	Two component regulator propeller
FE838_RS12810	COG2205	protein histidine kinase activity
FE838_RS12815	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FE838_RS12820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE838_RS12830	COG3250	beta-galactosidase activity
FE838_RS12845	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE838_RS12850	COG4206	TonB-dependent receptor
FE838_RS12850	COG1629	transport
FE838_RS12860	COG5002	protein histidine kinase activity
FE838_RS12885	COG1760	l-serine dehydratase
FE838_RS12890	COG0598	Magnesium transport protein CorA
FE838_RS12895	COG1193	negative regulation of DNA recombination
FE838_RS12905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS12920	COG3250	beta-galactosidase activity
FE838_RS12930	COG0668	transmembrane transport
FE838_RS12935	COG1523	belongs to the glycosyl hydrolase 13 family
FE838_RS12945	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FE838_RS12955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS12965	COG1538	Outer membrane efflux protein
FE838_RS12970	COG0456	acetyltransferase
FE838_RS12980	COG3189	MarR family transcriptional regulator
FE838_RS12985	COG0561	phosphatase activity
FE838_RS12990	COG1169	isochorismate synthase
FE838_RS12995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FE838_RS13000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FE838_RS13005	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS13025	COG4206	TonB-dependent receptor
FE838_RS13025	COG1629	transport
FE838_RS13065	COG0783	Belongs to the Dps family
FE838_RS13070	COG0583	DNA-binding transcription factor activity
FE838_RS13080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FE838_RS13100	COG1595	DNA-templated transcription, initiation
FE838_RS13110	COG4771	TonB-dependent receptor
FE838_RS13120	COG0584	glycerophosphoryl diester phosphodiesterase
FE838_RS13125	COG0584	glycerophosphoryl diester phosphodiesterase
FE838_RS13130	COG2271	Major facilitator Superfamily
FE838_RS13175	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS13180	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FE838_RS13185	COG1882	Formate acetyltransferase
FE838_RS13195	COG4974	Belongs to the 'phage' integrase family
FE838_RS13225	COG5290	Psort location Cytoplasmic, score
FE838_RS13275	COG0326	Molecular chaperone. Has ATPase activity
FE838_RS13430	COG1475	DNA binding
FE838_RS13450	COG0584	glycerophosphoryl diester phosphodiesterase
FE838_RS13495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FE838_RS13540	COG0784	Response regulator, receiver
FE838_RS13540	COG2198	Histidine kinase
FE838_RS13540	COG5002	protein histidine kinase activity
FE838_RS13600	COG4206	TonB-dependent receptor
FE838_RS13600	COG1629	transport
FE838_RS13665	COG1442	glycosyl transferase family 8
FE838_RS13665	COG1216	Glycosyl transferase, family 2
FE838_RS13675	COG1215	transferase activity, transferring glycosyl groups
FE838_RS13680	COG1216	Glycosyl transferase, family 2
FE838_RS13695	COG1216	Glycosyl transferase, family 2
FE838_RS13695	COG1442	glycosyl transferase family 8
FE838_RS13700	COG1216	Glycosyl transferase, family 2
FE838_RS13715	COG0438	transferase activity, transferring glycosyl groups
FE838_RS13720	COG0438	transferase activity, transferring glycosyl groups
FE838_RS13725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE838_RS13775	COG2885	chlorophyll binding
FE838_RS13810	COG1132	(ABC) transporter
FE838_RS13830	COG4974	Belongs to the 'phage' integrase family
FE838_RS13840	COG2003	Belongs to the UPF0758 family
FE838_RS13980	COG0551	DNA topoisomerase type I activity
FE838_RS13980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE838_RS14025	COG0798	PFAM Bile acid sodium symporter
FE838_RS14030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE838_RS14070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FE838_RS14110	COG1028	Short-chain dehydrogenase reductase Sdr
FE838_RS14115	COG3385	transposase activity
FE838_RS14120	COG1082	Xylose isomerase domain protein TIM barrel
FE838_RS14125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FE838_RS14150	COG3292	Two component regulator propeller
FE838_RS14150	COG0745	RESPONSE REGULATOR receiver
FE838_RS14150	COG3292	Two component regulator propeller
FE838_RS14150	COG2205	protein histidine kinase activity
FE838_RS14150	COG0745	RESPONSE REGULATOR receiver
FE838_RS14150	COG2205	protein histidine kinase activity
FE838_RS14155	COG1595	DNA-templated transcription, initiation
FE838_RS14160	COG1629	transport
FE838_RS14160	COG4206	TonB-dependent receptor
FE838_RS14170	COG5492	domain, Protein
FE838_RS14185	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FE838_RS14195	COG1253	flavin adenine dinucleotide binding
FE838_RS14200	COG0501	Belongs to the peptidase M48B family
FE838_RS14225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE838_RS14230	COG0482	sulfurtransferase activity
FE838_RS14235	COG2197	response regulator
FE838_RS14260	COG2814	Major facilitator Superfamily
FE838_RS14265	COG4953	penicillin-binding protein 1C
FE838_RS14270	COG2373	Large extracellular alpha-helical protein
FE838_RS14275	COG0545	Peptidyl-prolyl cis-trans isomerase
FE838_RS14345	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FE838_RS14350	COG0646	methionine synthase
FE838_RS14350	COG1410	methionine synthase
FE838_RS14355	COG0778	Nitroreductase
FE838_RS14360	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE838_RS14370	COG0572	uridine kinase
FE838_RS14380	COG4232	protein-disulfide reductase activity
FE838_RS14385	COG1741	Belongs to the pirin family
FE838_RS14400	COG1629	transport
FE838_RS14405	COG0702	epimerase
FE838_RS14430	COG2271	Major facilitator Superfamily
FE838_RS14450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE838_RS14455	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE838_RS14460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FE838_RS14465	COG0131	Imidazoleglycerol-phosphate dehydratase
FE838_RS14475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE838_RS14475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE838_RS14480	COG1629	transport
FE838_RS14480	COG4206	TonB-dependent receptor
FE838_RS14530	COG1592	Rubrerythrin
FE838_RS14530	COG1773	rubredoxin
FE838_RS14550	COG1373	ATPase (AAA superfamily
FE838_RS14560	COG3279	Response regulator of the LytR AlgR family
FE838_RS14610	COG4974	Belongs to the 'phage' integrase family
FE838_RS14630	COG3591	Belongs to the peptidase S1B family
FE838_RS14635	COG3591	Belongs to the peptidase S1B family
FE838_RS14640	COG0641	radical SAM
FE838_RS14670	COG0420	3'-5' exonuclease activity
FE838_RS14680	COG1408	metallophosphoesterase
FE838_RS14695	COG1410	methionine synthase
FE838_RS14695	COG0646	methionine synthase
FE838_RS14705	COG0463	Glycosyl transferase, family 2
FE838_RS14710	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE838_RS14720	COG1032	radical SAM domain protein
FE838_RS14740	COG0363	glucosamine-6-phosphate deaminase activity
FE838_RS14745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE838_RS14780	COG3292	Two component regulator propeller
FE838_RS14780	COG2205	protein histidine kinase activity
FE838_RS14780	COG0745	RESPONSE REGULATOR receiver
FE838_RS14785	COG1629	transport
FE838_RS14790	COG0702	epimerase
FE838_RS14805	COG4771	TonB-dependent receptor
FE838_RS14845	COG3328	transposase activity
FE838_RS14865	COG0811	peptide transport
FE838_RS14870	COG0848	biopolymer transport protein
FE838_RS14915	COG1131	(ABC) transporter
FE838_RS14950	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE838_RS14990	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE838_RS14995	COG0022	dehydrogenase e1 component
FE838_RS15005	COG2264	protein methyltransferase activity
FE838_RS15020	COG4206	TonB-dependent receptor
FE838_RS15020	COG1629	transport
FE838_RS15035	COG0590	tRNA wobble adenosine to inosine editing
FE838_RS15040	COG0673	inositol 2-dehydrogenase activity
FE838_RS15065	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FE838_RS15105	COG0714	Associated with various cellular activities
FE838_RS15110	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FE838_RS15125	COG1501	Belongs to the glycosyl hydrolase 31 family
FE838_RS15130	COG5012	cobalamin binding
FE838_RS15160	COG0698	ribose 5-phosphate isomerase
FE838_RS15165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE838_RS15180	COG1070	Carbohydrate kinase
FE838_RS15185	COG2160	L-arabinose isomerase activity
FE838_RS15230	COG0702	epimerase
FE838_RS15235	COG4206	TonB-dependent receptor
FE838_RS15235	COG1629	transport
FE838_RS15240	COG0702	epimerase
FE838_RS15245	COG1629	transport
FE838_RS15245	COG4206	TonB-dependent receptor
FE838_RS15255	COG3292	Two component regulator propeller
FE838_RS15255	COG0745	RESPONSE REGULATOR receiver
FE838_RS15255	COG2205	protein histidine kinase activity
FE838_RS15260	COG3507	Belongs to the glycosyl hydrolase 43 family
FE838_RS15270	COG3507	Belongs to the glycosyl hydrolase 43 family
FE838_RS15275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FE838_RS15290	COG1482	cell wall glycoprotein biosynthetic process
FE838_RS15330	COG1086	Polysaccharide biosynthesis protein
FE838_RS15425	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS15465	COG4221	oxidoreductase activity
FE838_RS15480	COG3273	potassium ion transport
FE838_RS15480	COG0471	metal ion transport
FE838_RS15485	COG0529	Catalyzes the synthesis of activated sulfate
FE838_RS15490	COG0175	sulfate reduction
FE838_RS15495	COG2895	sulfate adenylyltransferase (ATP) activity
FE838_RS15515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE838_RS15520	COG0242	peptide deformylase activity
FE838_RS15530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FE838_RS15535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FE838_RS15540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FE838_RS15545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FE838_RS15555	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FE838_RS15560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FE838_RS15565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FE838_RS15565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE838_RS15565	COG1013	pyruvate-flavodoxin oxidoreductase activity
FE838_RS15565	COG0674	pyruvate-flavodoxin oxidoreductase activity
FE838_RS15575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE838_RS15590	COG1940	carbohydrate kinase activity
FE838_RS15595	COG2081	HI0933 family
FE838_RS15605	COG2814	Major facilitator Superfamily
FE838_RS15615	COG4771	TonB-dependent receptor
FE838_RS15650	COG2755	lipolytic protein G-D-S-L family
FE838_RS15650	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FE838_RS15660	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS15685	COG4771	TonB-dependent receptor
FE838_RS15710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS15715	COG0657	acetylesterase activity
FE838_RS15715	COG2755	lipolytic protein G-D-S-L family
FE838_RS15725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS15730	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS15735	COG3250	beta-galactosidase activity
FE838_RS15755	COG1091	dTDP-4-dehydrorhamnose reductase activity
FE838_RS15805	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FE838_RS15815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FE838_RS15845	COG4771	TonB-dependent receptor
FE838_RS15850	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE838_RS15860	COG2721	sulfolactate sulfo-lyase activity
FE838_RS15865	COG1609	Transcriptional regulator
FE838_RS15900	COG1429	ligase activity, forming nitrogen-metal bonds
FE838_RS15905	COG4771	TonB-dependent receptor
FE838_RS15920	COG1230	cation diffusion facilitator family transporter
FE838_RS15925	COG0490	domain, Protein
FE838_RS15925	COG2985	domain, Protein
FE838_RS15935	COG4771	TonB-dependent receptor
FE838_RS15945	COG4771	TonB-dependent receptor
FE838_RS15955	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS15970	COG1132	(ABC) transporter
FE838_RS16010	COG0716	FMN binding
FE838_RS16015	COG0138	bifunctional purine biosynthesis protein purh
FE838_RS16025	COG2197	response regulator
FE838_RS16030	COG0110	maltose O-acetyltransferase activity
FE838_RS16040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE838_RS16045	COG3292	Two component regulator propeller
FE838_RS16045	COG0745	RESPONSE REGULATOR receiver
FE838_RS16045	COG2205	protein histidine kinase activity
FE838_RS16055	COG0252	asparaginase activity
FE838_RS16060	COG0159	tryptophan synthase activity
FE838_RS16065	COG0135	phosphoribosylanthranilate isomerase activity
FE838_RS16070	COG0134	indole-3-glycerol-phosphate synthase activity
FE838_RS16075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE838_RS16085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE838_RS16090	COG0133	tryptophan synthase activity
FE838_RS16100	COG1979	alcohol dehydrogenase
FE838_RS16110	COG0471	metal ion transport
FE838_RS16110	COG0490	domain, Protein
FE838_RS16120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE838_RS16135	COG0004	ammonium transporteR
FE838_RS16140	COG0347	Belongs to the P(II) protein family
FE838_RS16150	COG0436	Aminotransferase
FE838_RS16155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FE838_RS16170	COG0367	asparagine synthase
FE838_RS16180	COG0067	glutamate synthase
FE838_RS16180	COG0069	glutamate synthase activity
FE838_RS16180	COG0070	glutamate synthase
FE838_RS16185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE838_RS16195	COG0505	Belongs to the CarA family
FE838_RS16200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FE838_RS16210	COG2207	Transcriptional regulator
FE838_RS16210	COG1917	Cupin 2, conserved barrel domain protein
FE838_RS16225	COG1131	(ABC) transporter
FE838_RS16230	COG0842	Transport permease protein
FE838_RS16235	COG0842	Transport permease protein
FE838_RS16245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FE838_RS16250	COG2949	membrane
FE838_RS16265	COG0556	nucleotide-excision repair
FE838_RS16270	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FE838_RS16300	COG3942	CHAP domain
FE838_RS16300	COG1388	LysM domain
FE838_RS16310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE838_RS16315	COG3104	oligopeptide transport
FE838_RS16325	COG1695	Transcriptional regulator
FE838_RS16330	COG1983	PspC domain protein
FE838_RS16350	COG0823	Involved in the tonB-independent uptake of proteins
FE838_RS16350	COG1506	peptidase
FE838_RS16355	COG0534	Mate efflux family protein
FE838_RS16360	COG0706	membrane insertase activity
FE838_RS16365	COG0504	CTP synthase activity
FE838_RS16420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FE838_RS16425	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE838_RS16455	COG0438	transferase activity, transferring glycosyl groups
FE838_RS16480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE838_RS16520	COG4656	Part of a membrane complex involved in electron transport
FE838_RS16525	COG4658	electron transport chain
FE838_RS16530	COG4659	FMN binding
FE838_RS16535	COG4660	Part of a membrane complex involved in electron transport
FE838_RS16540	COG4657	Part of a membrane complex involved in electron transport
FE838_RS16545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE838_RS16550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FE838_RS16555	COG0305	Participates in initiation and elongation during chromosome replication
FE838_RS16560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE838_RS16560	COG0072	phenylalanine-tRNA ligase activity
FE838_RS16565	COG0217	transcriptional regulatory protein
FE838_RS16580	COG0708	Exodeoxyribonuclease III
FE838_RS16595	COG0481	GTPase activity
FE838_RS16605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE838_RS16625	COG0024	Methionine aminopeptidase
FE838_RS16645	COG0564	pseudouridine synthase activity
FE838_RS16650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FE838_RS16655	COG0574	Belongs to the PEP-utilizing enzyme family
FE838_RS16655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE838_RS16670	COG0352	thiamine-phosphate diphosphorylase activity
FE838_RS16675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FE838_RS16680	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE838_RS16685	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FE838_RS16690	COG2022	thiamine diphosphate biosynthetic process
FE838_RS16695	COG0352	thiamine-phosphate diphosphorylase activity
FE838_RS16705	COG5002	protein histidine kinase activity
FE838_RS16720	COG0210	DNA helicase
FE838_RS16775	COG0681	Belongs to the peptidase S26 family
FE838_RS16785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS16805	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE838_RS16850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FE838_RS16855	COG3118	belongs to the thioredoxin family
FE838_RS16875	COG2205	protein histidine kinase activity
FE838_RS16880	COG0745	RESPONSE REGULATOR receiver
FE838_RS16885	COG1082	Xylose isomerase domain protein TIM barrel
FE838_RS16890	COG0318	PFAM AMP-dependent synthetase and ligase
FE838_RS16895	COG3263	regulation of cellular component size
FE838_RS16900	COG2233	PERMEase
FE838_RS16905	COG1151	hydroxylamine reductase activity
FE838_RS16940	COG1136	(ABC) transporter
FE838_RS16950	COG0534	Mate efflux family protein
FE838_RS16960	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FE838_RS16970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE838_RS16990	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FE838_RS17005	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS17030	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FE838_RS17035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FE838_RS17045	COG0356	it plays a direct role in the translocation of protons across the membrane
FE838_RS17050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE838_RS17055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FE838_RS17060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE838_RS17065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FE838_RS17070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FE838_RS17080	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE838_RS17085	COG2431	L-lysine efflux transmembrane transporter activity
FE838_RS17095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE838_RS17110	COG2207	Transcriptional regulator
FE838_RS17150	COG2985	domain, Protein
FE838_RS17155	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FE838_RS17160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FE838_RS17175	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FE838_RS17180	COG0540	Belongs to the ATCase OTCase family
FE838_RS17195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FE838_RS17210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE838_RS17215	COG2205	protein histidine kinase activity
FE838_RS17240	COG4206	TonB-dependent receptor
FE838_RS17240	COG1629	transport
FE838_RS17255	COG3250	beta-galactosidase activity
FE838_RS17260	COG3153	acetyltransferase
FE838_RS17275	COG0745	RESPONSE REGULATOR receiver
FE838_RS17275	COG3292	Two component regulator propeller
FE838_RS17275	COG2205	protein histidine kinase activity
FE838_RS17300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE838_RS17310	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE838_RS17315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE838_RS17330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FE838_RS17355	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE838_RS17365	COG2326	polyphosphate kinase activity
FE838_RS17410	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FE838_RS17415	COG0045	succinate-CoA ligase (ADP-forming) activity
FE838_RS17420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FE838_RS17425	COG0351	phosphomethylpyrimidine kinase
FE838_RS17440	COG2115	Belongs to the xylose isomerase family
FE838_RS17445	COG2814	Major facilitator Superfamily
FE838_RS17445	COG0477	Major facilitator Superfamily
FE838_RS17490	COG0798	PFAM Bile acid sodium symporter
FE838_RS17495	COG3153	acetyltransferase
FE838_RS17495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE838_RS17505	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE838_RS17515	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FE838_RS17525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE838_RS17555	COG3015	lipoprotein NlpE involved in copper resistance
FE838_RS17560	COG0784	Response regulator, receiver
FE838_RS17560	COG2198	Histidine kinase
FE838_RS17560	COG2205	protein histidine kinase activity
FE838_RS17580	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FE838_RS17595	COG1904	glucuronate isomerase
FE838_RS17605	COG0246	Mannitol dehydrogenase
FE838_RS17635	COG0513	Belongs to the DEAD box helicase family
FE838_RS17640	COG3830	Belongs to the UPF0237 family
FE838_RS17640	COG0560	Phosphoserine phosphatase
FE838_RS17660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FE838_RS17665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FE838_RS17745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE838_RS17755	COG3852	Histidine kinase
FE838_RS17780	COG1136	(ABC) transporter
FE838_RS17815	COG4771	TonB-dependent receptor
FE838_RS17830	COG0156	8-amino-7-oxononanoate synthase activity
FE838_RS17835	COG1597	lipid kinase activity
FE838_RS17840	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FE838_RS17870	COG1132	(ABC) transporter
FE838_RS17890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FE838_RS17920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE838_RS17935	COG0543	2 iron, 2 sulfur cluster binding
FE838_RS17940	COG0167	dihydroorotate dehydrogenase activity
FE838_RS17945	COG0336	Belongs to the RNA methyltransferase TrmD family
FE838_RS17950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FE838_RS17955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE838_RS17980	COG0326	Molecular chaperone. Has ATPase activity
FE838_RS18030	COG2304	oxidoreductase activity
FE838_RS18045	COG0714	Associated with various cellular activities
FE838_RS18050	COG0776	regulation of translation
FE838_RS18055	COG0776	regulation of translation
FE838_RS18060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FE838_RS18065	COG0552	protein localization to endoplasmic reticulum
FE838_RS18075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FE838_RS18080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FE838_RS18100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FE838_RS18135	COG2205	protein histidine kinase activity
FE838_RS18140	COG0745	RESPONSE REGULATOR receiver
FE838_RS18145	COG0442	prolyl-tRNA aminoacylation
FE838_RS18245	COG0582	viral genome integration into host DNA
FE838_RS18270	COG4974	Belongs to the 'phage' integrase family
FE838_RS18285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS18300	COG3292	Two component regulator propeller
FE838_RS18300	COG0745	RESPONSE REGULATOR receiver
FE838_RS18300	COG2205	protein histidine kinase activity
FE838_RS18310	COG4206	TonB-dependent receptor
FE838_RS18340	COG1595	DNA-templated transcription, initiation
FE838_RS18360	COG1011	Hydrolase
FE838_RS18370	COG0300	oxidoreductase activity
FE838_RS18385	COG2966	Psort location CytoplasmicMembrane, score
FE838_RS18415	COG3292	Two component regulator propeller
FE838_RS18415	COG0745	RESPONSE REGULATOR receiver
FE838_RS18415	COG2205	protein histidine kinase activity
FE838_RS18425	COG3250	beta-galactosidase activity
FE838_RS18455	COG5002	protein histidine kinase activity
FE838_RS18460	COG0745	RESPONSE REGULATOR receiver
FE838_RS18470	COG3250	beta-galactosidase activity
FE838_RS18490	COG3250	beta-galactosidase activity
FE838_RS18500	COG2205	protein histidine kinase activity
FE838_RS18500	COG0784	Response regulator, receiver
FE838_RS18500	COG5002	protein histidine kinase activity
FE838_RS18550	COG0657	acetylesterase activity
FE838_RS18550	COG2755	lipolytic protein G-D-S-L family
FE838_RS18555	COG0167	dihydroorotate dehydrogenase activity
FE838_RS18565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FE838_RS18575	COG3408	Glycogen debranching enzyme
FE838_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
FE838_RS18605	COG3408	Glycogen debranching enzyme
FE838_RS18630	COG0702	epimerase
FE838_RS18635	COG1629	transport
FE838_RS18635	COG4206	TonB-dependent receptor
FE838_RS18645	COG0702	epimerase
FE838_RS18650	COG1629	transport
FE838_RS18665	COG3537	Alpha-1,2-mannosidase
FE838_RS18670	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FE838_RS18705	COG1629	transport
FE838_RS18705	COG4206	TonB-dependent receptor
FE838_RS18735	COG1629	transport
FE838_RS18735	COG4206	TonB-dependent receptor
FE838_RS18760	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS18780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FE838_RS18845	COG1475	DNA binding
FE838_RS18850	COG3969	phosphoadenosine phosphosulfate
FE838_RS18880	COG3275	phosphorelay sensor kinase activity
FE838_RS18900	COG1678	Uncharacterized ACR, COG1678
FE838_RS18915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FE838_RS18925	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FE838_RS18955	COG0321	lipoyl(octanoyl) transferase activity
FE838_RS18965	COG2217	Heavy metal translocating P-type atpase
FE838_RS19015	COG0010	Belongs to the arginase family
FE838_RS19020	COG0058	SHG alpha-glucan phosphorylase activity
FE838_RS19025	COG4651	solute:proton antiporter activity
FE838_RS19025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE838_RS19030	COG0205	6-phosphofructokinase activity
FE838_RS19045	COG0588	phosphoglycerate mutase activity
FE838_RS19050	COG1830	Aldolase
FE838_RS19060	COG2095	MarC family integral membrane protein
FE838_RS19090	COG0667	Aldo Keto reductase
FE838_RS19105	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE838_RS19110	COG4771	TonB-dependent receptor
FE838_RS19120	COG2706	6-phosphogluconolactonase activity
FE838_RS19125	COG2207	Transcriptional regulator
FE838_RS19200	COG4974	Belongs to the 'phage' integrase family
FE838_RS19240	COG0357	Ribosomal RNA small subunit methyltransferase G
FE838_RS19245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE838_RS19250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE838_RS19250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FE838_RS19265	COG1739	Uncharacterized protein family UPF0029
FE838_RS19280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FE838_RS19290	COG2871	sodium ion transport
FE838_RS19295	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE838_RS19305	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FE838_RS19310	COG1805	sodium ion transport
FE838_RS19345	COG1215	transferase activity, transferring glycosyl groups
FE838_RS19355	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS19395	COG1216	Glycosyl transferase, family 2
FE838_RS19395	COG1442	glycosyl transferase family 8
FE838_RS19400	COG2244	polysaccharide biosynthetic process
FE838_RS19410	COG1442	glycosyl transferase family 8
FE838_RS19420	COG1215	transferase activity, transferring glycosyl groups
FE838_RS19450	COG0488	(ABC) transporter
FE838_RS19470	COG1162	GTPase activity
FE838_RS19480	COG2755	lipolytic protein G-D-S-L family
FE838_RS19480	COG0657	acetylesterase activity
FE838_RS19485	COG0534	Mate efflux family protein
FE838_RS19490	COG2885	chlorophyll binding
FE838_RS19495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE838_RS19510	COG1704	LemA family
FE838_RS19515	COG0501	Belongs to the peptidase M48B family
FE838_RS19540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE838_RS19550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE838_RS19580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS19585	COG1136	(ABC) transporter
FE838_RS19590	COG0577	efflux transmembrane transporter activity
FE838_RS19590	COG1136	(ABC) transporter
FE838_RS19600	COG3279	Response regulator of the LytR AlgR family
FE838_RS19605	COG2135	peptidase activity
FE838_RS19610	COG2837	iron assimilation
FE838_RS19620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FE838_RS19630	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FE838_RS19635	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FE838_RS19640	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FE838_RS19645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE838_RS19650	COG0318	PFAM AMP-dependent synthetase and ligase
FE838_RS19660	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FE838_RS19665	COG0490	domain, Protein
FE838_RS19665	COG2985	domain, Protein
FE838_RS19705	COG0737	Belongs to the 5'-nucleotidase family
FE838_RS19710	COG2205	protein histidine kinase activity
FE838_RS19710	COG2202	Pas domain
FE838_RS19715	COG2183	response to ionizing radiation
FE838_RS19730	COG0488	(ABC) transporter
FE838_RS19735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FE838_RS19740	COG0484	heat shock protein binding
FE838_RS19820	COG1733	regulation of RNA biosynthetic process
FE838_RS19830	COG2198	Histidine kinase
FE838_RS19830	COG2205	protein histidine kinase activity
FE838_RS19830	COG0784	Response regulator, receiver
FE838_RS19830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE838_RS19840	COG3275	phosphorelay sensor kinase activity
FE838_RS19865	COG0228	four-way junction DNA binding
FE838_RS19870	COG2188	Transcriptional regulator
FE838_RS19875	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FE838_RS19885	COG1070	Carbohydrate kinase
FE838_RS19895	COG0738	Major facilitator superfamily
FE838_RS19940	COG2207	Transcriptional regulator
FE838_RS19955	COG1177	transmembrane transport
FE838_RS19960	COG1176	ABC-type spermidine putrescine transport system, permease component I
FE838_RS19965	COG3842	ATPase activity
FE838_RS19970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FE838_RS19975	COG0058	SHG alpha-glucan phosphorylase activity
FE838_RS19985	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FE838_RS20005	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FE838_RS20030	COG1725	Transcriptional regulator
FE838_RS20040	COG1131	(ABC) transporter
FE838_RS20085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FE838_RS20090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE838_RS20095	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS20110	COG1295	ribonuclease BN
FE838_RS20125	COG2972	Histidine kinase
FE838_RS20135	COG0704	Plays a role in the regulation of phosphate uptake
FE838_RS20140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE838_RS20145	COG0581	inorganic phosphate transmembrane transporter activity
FE838_RS20150	COG0573	inorganic phosphate transmembrane transporter activity
FE838_RS20160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE838_RS20170	COG0586	Pfam SNARE associated Golgi protein
FE838_RS20180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FE838_RS20195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FE838_RS20200	COG0167	dihydroorotate dehydrogenase activity
FE838_RS20205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FE838_RS20230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FE838_RS20290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE838_RS20300	COG1216	Glycosyl transferase, family 2
FE838_RS20335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE838_RS20340	COG0497	DNA recombination
FE838_RS20355	COG0592	DNA-directed DNA polymerase activity
FE838_RS20370	COG0321	lipoyl(octanoyl) transferase activity
FE838_RS20370	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FE838_RS20375	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FE838_RS20385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE838_RS20390	COG0156	8-amino-7-oxononanoate synthase activity
FE838_RS20405	COG0019	diaminopimelate decarboxylase activity
FE838_RS20410	COG0527	aspartate kinase activity
FE838_RS20415	COG2884	Cell division ATP-binding protein ftsE
FE838_RS20420	COG0140	phosphoribosyl-ATP diphosphatase activity
FE838_RS20420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE838_RS20425	COG0107	imidazoleglycerol-phosphate synthase activity
FE838_RS20430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FE838_RS20435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE838_RS20440	COG0788	formyltetrahydrofolate deformylase activity
FE838_RS20455	COG0693	protein deglycase activity
FE838_RS20460	COG0656	L-ascorbic acid biosynthetic process
FE838_RS20480	COG0534	Mate efflux family protein
FE838_RS20485	COG2076	Multidrug Resistance protein
FE838_RS20500	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE838_RS20500	COG2885	chlorophyll binding
FE838_RS20535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FE838_RS20550	COG2814	Major facilitator Superfamily
FE838_RS20575	COG1309	transcriptional regulator
FE838_RS20580	COG1924	4 iron, 4 sulfur cluster binding
FE838_RS20600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE838_RS20605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE838_RS20620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE838_RS20630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FE838_RS20645	COG4771	TonB-dependent receptor
FE838_RS20705	COG1312	Catalyzes the dehydration of D-mannonate
FE838_RS20710	COG1028	Short-chain dehydrogenase reductase Sdr
FE838_RS20715	COG1609	Transcriptional regulator
FE838_RS20730	COG1929	Belongs to the glycerate kinase type-1 family
FE838_RS20735	COG2223	nitrite transmembrane transporter activity
FE838_RS20745	COG4771	TonB-dependent receptor
FE838_RS20755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FE838_RS20755	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE838_RS20770	COG2226	methyltransferase
FE838_RS20780	COG0784	Response regulator, receiver
FE838_RS20780	COG5002	protein histidine kinase activity
FE838_RS20785	COG0511	ligase activity, forming carbon-carbon bonds
FE838_RS20790	COG0439	Biotin carboxylase
FE838_RS20795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE838_RS20810	COG1620	l-lactate permease
FE838_RS20815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FE838_RS20820	COG1690	Belongs to the RtcB family
FE838_RS20860	COG0110	maltose O-acetyltransferase activity
FE838_RS20870	COG0577	efflux transmembrane transporter activity
FE838_RS20875	COG0577	efflux transmembrane transporter activity
FE838_RS20875	COG1136	(ABC) transporter
FE838_RS20900	COG0628	permease
FE838_RS20905	COG1215	transferase activity, transferring glycosyl groups
FE838_RS20915	COG0569	domain protein
FE838_RS20915	COG0189	ligase activity
FE838_RS20920	COG0577	efflux transmembrane transporter activity
FE838_RS20920	COG1136	(ABC) transporter
FE838_RS20925	COG0436	Aminotransferase
FE838_RS20940	COG0488	(ABC) transporter
FE838_RS20955	COG0745	RESPONSE REGULATOR receiver
FE838_RS20960	COG5002	protein histidine kinase activity
FE838_RS21005	COG3033	Beta-eliminating lyase
FE838_RS21030	COG0629	single-stranded DNA binding
FE838_RS21035	COG1194	a g-specific adenine glycosylase
FE838_RS21045	COG1530	ribonuclease E activity
FE838_RS21050	COG2885	chlorophyll binding
FE838_RS21065	COG2885	chlorophyll binding
FE838_RS21115	COG0305	Participates in initiation and elongation during chromosome replication
FE838_RS21130	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS21150	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FE838_RS21160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FE838_RS21175	COG4191	Histidine kinase
FE838_RS21180	COG2204	response regulator
FE838_RS21190	COG0784	Response regulator, receiver
FE838_RS21190	COG2205	protein histidine kinase activity
FE838_RS21190	COG5002	protein histidine kinase activity
FE838_RS21220	COG1252	NADH dehydrogenase
FE838_RS21225	COG1705	Flagellar rod assembly protein muramidase FlgJ
FE838_RS21240	COG3059	membrane
FE838_RS21245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE838_RS21250	COG0488	(ABC) transporter
FE838_RS21275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE838_RS21285	COG0739	heme binding
FE838_RS21290	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE838_RS21295	COG1629	transport
FE838_RS21295	COG4206	TonB-dependent receptor
FE838_RS21305	COG0686	Belongs to the AlaDH PNT family
FE838_RS21350	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FE838_RS21360	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FE838_RS21370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE838_RS21400	COG1595	DNA-templated transcription, initiation
FE838_RS21415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FE838_RS21420	COG1741	Belongs to the pirin family
FE838_RS21425	COG0259	pyridoxamine-phosphate oxidase activity
FE838_RS21515	COG1918	ferrous iron import across plasma membrane
FE838_RS21515	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FE838_RS21520	COG0037	tRNA processing
FE838_RS21535	COG3119	arylsulfatase activity
FE838_RS21540	COG2202	Pas domain
FE838_RS21540	COG2205	protein histidine kinase activity
FE838_RS21545	COG2202	Pas domain
FE838_RS21545	COG2205	protein histidine kinase activity
FE838_RS21550	COG0534	Mate efflux family protein
FE838_RS21555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE838_RS21575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FE838_RS21580	COG1858	cytochrome C peroxidase
FE838_RS21585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FE838_RS21600	COG1983	PspC domain protein
FE838_RS21605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FE838_RS21630	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE838_RS21650	COG4206	TonB-dependent receptor
FE838_RS21650	COG1629	transport
FE838_RS21665	COG3119	arylsulfatase activity
FE838_RS21670	COG0668	transmembrane transport
FE838_RS21675	COG3119	arylsulfatase activity
FE838_RS21685	COG3250	beta-galactosidase activity
FE838_RS21690	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FE838_RS21695	COG3119	arylsulfatase activity
FE838_RS21705	COG0702	epimerase
FE838_RS21710	COG4206	TonB-dependent receptor
FE838_RS21710	COG1629	transport
FE838_RS21720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE838_RS21725	COG1660	Displays ATPase and GTPase activities
FE838_RS21730	COG2205	protein histidine kinase activity
FE838_RS21730	COG3292	Two component regulator propeller
FE838_RS21730	COG2205	protein histidine kinase activity
FE838_RS21730	COG0745	RESPONSE REGULATOR receiver
FE838_RS21730	COG0745	RESPONSE REGULATOR receiver
FE838_RS21730	COG3292	Two component regulator propeller
FE838_RS21735	COG3119	arylsulfatase activity
FE838_RS21785	COG1216	Glycosyl transferase, family 2
FE838_RS21790	COG1216	Glycosyl transferase, family 2
FE838_RS21800	COG1442	glycosyl transferase family 8
FE838_RS21800	COG1216	Glycosyl transferase, family 2
FE838_RS21810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FE838_RS21820	COG2244	polysaccharide biosynthetic process
FE838_RS21850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE838_RS21855	COG1830	Aldolase
FE838_RS21860	COG0588	phosphoglycerate mutase activity
FE838_RS21865	COG2205	protein histidine kinase activity
FE838_RS21865	COG0784	Response regulator, receiver
FE838_RS21870	COG1119	ATPase activity
FE838_RS21875	COG1523	belongs to the glycosyl hydrolase 13 family
FE838_RS21880	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FE838_RS21895	COG0560	Phosphoserine phosphatase
FE838_RS21910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FE838_RS21915	COG2814	Major facilitator Superfamily
FE838_RS21920	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE838_RS21925	COG0126	phosphoglycerate kinase activity
FE838_RS21945	COG0424	maF-like protein
FE838_RS21965	COG0778	Nitroreductase
FE838_RS21975	COG0288	reversible hydration of carbon dioxide
FE838_RS21985	COG4771	TonB-dependent receptor
FE838_RS22000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE838_RS22010	COG0511	ligase activity, forming carbon-carbon bonds
FE838_RS22015	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FE838_RS22025	COG0191	fructose-bisphosphate aldolase activity
FE838_RS22030	COG0254	rRNA binding
FE838_RS22035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS22040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE838_RS22115	COG1216	Glycosyl transferase, family 2
FE838_RS22135	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE838_RS22145	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FE838_RS22150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FE838_RS22175	COG4750	Nucleotidyl transferase
FE838_RS22215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FE838_RS22230	COG1280	lysine exporter protein (LysE YggA)
FE838_RS22240	COG3292	Two component regulator propeller
FE838_RS22240	COG0745	RESPONSE REGULATOR receiver
FE838_RS22240	COG2205	protein histidine kinase activity
FE838_RS22240	COG3292	Two component regulator propeller
FE838_RS22240	COG0745	RESPONSE REGULATOR receiver
FE838_RS22240	COG2205	protein histidine kinase activity
FE838_RS22255	COG1649	PFAM Uncharacterised BCR, COG1649
FE838_RS22280	COG1966	Carbon starvation protein
FE838_RS22315	COG2113	Glycine betaine
FE838_RS22320	COG4176	ABC-type proline glycine betaine transport system permease component
FE838_RS22340	COG3292	Two component regulator propeller
FE838_RS22340	COG0745	RESPONSE REGULATOR receiver
FE838_RS22340	COG2205	protein histidine kinase activity
FE838_RS22355	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FE838_RS22355	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FE838_RS22365	COG1621	beta-fructofuranosidase activity
FE838_RS22380	COG0561	phosphatase activity
FE838_RS22385	COG4206	TonB-dependent receptor
FE838_RS22385	COG1629	transport
FE838_RS22395	COG1621	beta-fructofuranosidase activity
FE838_RS22410	COG3250	beta-galactosidase activity
FE838_RS22415	COG3537	Alpha-1,2-mannosidase
FE838_RS22440	COG1629	transport
FE838_RS22450	COG3250	beta-galactosidase activity
FE838_RS22460	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS22470	COG1472	Belongs to the glycosyl hydrolase 3 family
FE838_RS22480	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE838_RS22485	COG0475	glutathione-regulated potassium exporter activity
FE838_RS22525	COG2885	chlorophyll binding
FE838_RS22540	COG3279	Response regulator of the LytR AlgR family
FE838_RS22575	COG2205	protein histidine kinase activity
FE838_RS22580	COG2205	protein histidine kinase activity
FE838_RS22595	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FE838_RS22600	COG1960	acyl-CoA dehydrogenase activity
FE838_RS22620	COG1956	GAF domain-containing protein
FE838_RS22630	COG0484	heat shock protein binding
FE838_RS22635	COG2194	sulfuric ester hydrolase activity
FE838_RS22675	COG3385	transposase activity
FE838_RS22715	COG0459	protein refolding
FE838_RS22720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FE838_RS22735	COG2205	protein histidine kinase activity
FE838_RS22735	COG5002	protein histidine kinase activity
FE838_RS22735	COG0784	Response regulator, receiver
FE838_RS22750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FE838_RS22760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FE838_RS22765	COG0823	Involved in the tonB-independent uptake of proteins
FE838_RS22765	COG1506	peptidase
FE838_RS22775	COG0124	histidyl-tRNA synthetase
FE838_RS22790	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE838_RS22815	COG0514	ATP-dependent DNA helicase (RecQ)
FE838_RS22830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FE838_RS22840	COG0671	phosphoesterase, PA-phosphatase related
FE838_RS22855	COG0473	3-isopropylmalate dehydrogenase activity
FE838_RS22860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE838_RS22865	COG0066	3-isopropylmalate dehydratase activity
FE838_RS22870	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FE838_RS22875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE838_RS22920	COG4948	Mandelate Racemase Muconate Lactonizing
FE838_RS22930	COG3507	Belongs to the glycosyl hydrolase 43 family
FE838_RS22935	COG0702	epimerase
FE838_RS22940	COG4771	TonB-dependent receptor
FE838_RS22960	COG0616	signal peptide processing
FE838_RS22965	COG1663	tetraacyldisaccharide 4'-kinase activity
FE838_RS22970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FE838_RS22975	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE838_RS22995	COG0513	Belongs to the DEAD box helicase family
FE838_RS23000	COG2070	2-Nitropropane dioxygenase
FE838_RS23005	COG0724	RNA recognition motif
FE838_RS23020	COG3973	AAA domain
FE838_RS23035	COG5433	transposase activity
FE838_RS23055	COG1704	LemA family
FE838_RS23070	COG0534	Mate efflux family protein
FE838_RS23080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FE838_RS23090	COG4977	sequence-specific DNA binding
FE838_RS23090	COG1917	Cupin 2, conserved barrel domain protein
FE838_RS23120	COG1028	Short-chain dehydrogenase reductase Sdr
FE838_RS23125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FE838_RS23135	COG0439	Biotin carboxylase
FE838_RS23140	COG0511	ligase activity, forming carbon-carbon bonds
FE838_RS23140	COG5016	pyruvate
FE838_RS23145	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE838_RS23155	COG2855	membrane
FE838_RS23165	COG2873	o-acetylhomoserine
FE838_RS23195	COG4974	Belongs to the 'phage' integrase family
FE838_RS23200	COG4974	Belongs to the 'phage' integrase family
FE838_RS23285	COG1192	Involved in chromosome partitioning
FE838_RS23310	COG1120	ATPase activity
FE838_RS23315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE838_RS23370	COG1538	Outer membrane efflux protein
FE838_RS23400	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE838_RS23420	COG0024	Methionine aminopeptidase
FE838_RS23425	COG0617	tRNA 3'-terminal CCA addition
FE838_RS23445	COG0632	four-way junction helicase activity
FE838_RS23450	COG0673	inositol 2-dehydrogenase activity
FE838_RS23470	COG1272	protein, Hemolysin III
FE838_RS23485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FE838_RS23510	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS23535	COG3328	transposase activity
FE838_RS23545	COG1328	CTP reductase activity
FE838_RS23555	COG2814	Major facilitator Superfamily
FE838_RS23560	COG0750	zinc metalloprotease
FE838_RS23565	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FE838_RS23575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE838_RS23580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE838_RS23600	COG0194	GDP metabolic process
FE838_RS23610	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FE838_RS23620	COG1408	metallophosphoesterase
FE838_RS23625	COG1575	Belongs to the MenA family. Type 1 subfamily
FE838_RS23630	COG1088	dTDP-glucose 4,6-dehydratase activity
FE838_RS23635	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FE838_RS23645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FE838_RS23665	COG2205	protein histidine kinase activity
FE838_RS23695	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE838_RS23715	COG4771	TonB-dependent receptor
FE838_RS23720	COG1629	transport
FE838_RS23730	COG2205	protein histidine kinase activity
FE838_RS23730	COG0784	Response regulator, receiver
FE838_RS23735	COG0488	(ABC) transporter
FE838_RS23785	COG1595	DNA-templated transcription, initiation
FE838_RS23800	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FE838_RS23810	COG1522	sequence-specific DNA binding
FE838_RS23840	COG0811	peptide transport
FE838_RS23850	COG0084	hydrolase, TatD family'
FE838_RS23870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FE838_RS23875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FE838_RS23880	COG0205	6-phosphofructokinase activity
FE838_RS23905	COG1902	pentaerythritol trinitrate reductase activity
FE838_RS23925	COG0372	Belongs to the citrate synthase family
FE838_RS23930	COG0538	isocitrate dehydrogenase activity
FE838_RS23940	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FE838_RS23945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FE838_RS23960	COG0028	Belongs to the TPP enzyme family
FE838_RS23965	COG0129	dihydroxy-acid dehydratase activity
FE838_RS23970	COG1047	Peptidyl-prolyl cis-trans
FE838_RS23975	COG3681	Belongs to the UPF0597 family
FE838_RS23995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FE838_RS24000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FE838_RS24020	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE838_RS24020	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE838_RS24025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FE838_RS24030	COG2985	domain, Protein
FE838_RS24030	COG0569	domain protein
FE838_RS24065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE838_RS24070	COG1120	ATPase activity
FE838_RS24085	COG2188	Transcriptional regulator
FE838_RS24105	COG4206	TonB-dependent receptor
FE838_RS24105	COG1629	transport
FE838_RS24165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE838_RS24170	COG1609	Transcriptional regulator
FE838_RS24170	COG2207	Transcriptional regulator
FE838_RS24180	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FE838_RS24185	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FE838_RS24190	COG0166	Belongs to the GPI family
FE838_RS24220	COG2502	aspartate--ammonia ligase
FE838_RS24225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FE838_RS24250	COG3876	Protein conserved in bacteria
FE838_RS24280	COG0860	N-Acetylmuramoyl-L-alanine amidase