locus-tag	class	description
FNR01_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNR01_RS00010	COG0778	Nitroreductase
FNR01_RS00020	COG1640	4-alpha-glucanotransferase
FNR01_RS00025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNR01_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNR01_RS00055	COG0318	PFAM AMP-dependent synthetase and ligase
FNR01_RS00065	COG0724	RNA recognition motif
FNR01_RS00075	COG0359	binds to the 23S rRNA
FNR01_RS00080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNR01_RS00085	COG0360	Binds together with S18 to 16S ribosomal RNA
FNR01_RS00105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNR01_RS00110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNR01_RS00125	COG2818	Glycosylase
FNR01_RS00140	COG1629	transport
FNR01_RS00140	COG4206	TonB-dependent receptor
FNR01_RS00180	COG2818	Glycosylase
FNR01_RS00185	COG3250	beta-galactosidase activity
FNR01_RS00205	COG1082	Xylose isomerase domain protein TIM barrel
FNR01_RS00230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNR01_RS00260	COG3279	Response regulator of the LytR AlgR family
FNR01_RS00265	COG3275	phosphorelay sensor kinase activity
FNR01_RS00275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNR01_RS00285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNR01_RS00295	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FNR01_RS00300	COG2333	competence protein COMEC
FNR01_RS00300	COG0658	competence protein
FNR01_RS00305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FNR01_RS00310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FNR01_RS00320	COG0009	L-threonylcarbamoyladenylate synthase
FNR01_RS00330	COG1609	Transcriptional regulator
FNR01_RS00330	COG2207	Transcriptional regulator
FNR01_RS00335	COG2133	pyrroloquinoline quinone binding
FNR01_RS00335	COG5183	chlorophyll binding
FNR01_RS00340	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNR01_RS00355	COG1785	Belongs to the alkaline phosphatase family
FNR01_RS00365	COG3537	Alpha-1,2-mannosidase
FNR01_RS00375	COG1629	transport
FNR01_RS00375	COG4206	TonB-dependent receptor
FNR01_RS00385	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS00390	COG3022	response to hydroperoxide
FNR01_RS00395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FNR01_RS00395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FNR01_RS00400	COG0514	ATP-dependent DNA helicase (RecQ)
FNR01_RS00420	COG0436	Aminotransferase
FNR01_RS00425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FNR01_RS00435	COG0358	DNA primase activity
FNR01_RS00440	COG0302	gtp cyclohydrolase
FNR01_RS00450	COG0149	triose-phosphate isomerase activity
FNR01_RS00465	COG0739	heme binding
FNR01_RS00470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNR01_RS00475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNR01_RS00490	COG0848	biopolymer transport protein
FNR01_RS00495	COG0811	peptide transport
FNR01_RS00505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNR01_RS00520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNR01_RS00530	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS00535	COG3250	beta-galactosidase activity
FNR01_RS00590	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNR01_RS00600	COG0039	L-malate dehydrogenase activity
FNR01_RS00635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNR01_RS00640	COG0673	inositol 2-dehydrogenase activity
FNR01_RS00655	COG0489	protein tyrosine kinase activity
FNR01_RS00660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNR01_RS00665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNR01_RS00675	COG1570	exodeoxyribonuclease VII activity
FNR01_RS00685	COG0482	sulfurtransferase activity
FNR01_RS00705	COG3507	Belongs to the glycosyl hydrolase 43 family
FNR01_RS00730	COG0702	epimerase
FNR01_RS00735	COG1629	transport
FNR01_RS00770	COG0673	inositol 2-dehydrogenase activity
FNR01_RS00775	COG1408	metallophosphoesterase
FNR01_RS00780	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNR01_RS00785	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNR01_RS00790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FNR01_RS00800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNR01_RS00805	COG0052	Belongs to the universal ribosomal protein uS2 family
FNR01_RS00810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FNR01_RS00815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNR01_RS00825	COG0017	Asparaginyl-tRNA synthetase
FNR01_RS00830	COG1187	pseudouridine synthase activity
FNR01_RS00850	COG0110	maltose O-acetyltransferase activity
FNR01_RS00855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNR01_RS00885	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNR01_RS00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNR01_RS00910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNR01_RS00915	COG0517	IMP dehydrogenase activity
FNR01_RS00915	COG0516	GMP reductase activity
FNR01_RS00920	COG0514	ATP-dependent DNA helicase (RecQ)
FNR01_RS00925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNR01_RS00930	COG0740	serine-type endopeptidase activity
FNR01_RS00935	COG0544	peptidyl-prolyl cis-trans isomerase activity
FNR01_RS00940	COG0724	RNA recognition motif
FNR01_RS00950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FNR01_RS00955	COG1127	ABC transporter
FNR01_RS00960	COG1160	GTP binding
FNR01_RS00965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNR01_RS00970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNR01_RS01020	COG4771	TonB-dependent receptor
FNR01_RS01025	COG0702	epimerase
FNR01_RS01050	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNR01_RS01055	COG2205	protein histidine kinase activity
FNR01_RS01055	COG2202	Pas domain
FNR01_RS01060	COG2205	protein histidine kinase activity
FNR01_RS01060	COG2202	Pas domain
FNR01_RS01080	COG0436	Aminotransferase
FNR01_RS01085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FNR01_RS01115	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS01120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNR01_RS01145	COG2017	converts alpha-aldose to the beta-anomer
FNR01_RS01150	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS01160	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNR01_RS01165	COG1082	Xylose isomerase domain protein TIM barrel
FNR01_RS01190	COG1629	transport
FNR01_RS01190	COG4206	TonB-dependent receptor
FNR01_RS01205	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS01210	COG0457	Tetratricopeptide repeat
FNR01_RS01215	COG2814	Major facilitator Superfamily
FNR01_RS01215	COG0477	Major facilitator Superfamily
FNR01_RS01220	COG4977	sequence-specific DNA binding
FNR01_RS01220	COG1917	Cupin 2, conserved barrel domain protein
FNR01_RS01240	COG2207	Transcriptional regulator
FNR01_RS01240	COG4753	response regulator
FNR01_RS01245	COG5002	protein histidine kinase activity
FNR01_RS01250	COG2205	protein histidine kinase activity
FNR01_RS01260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNR01_RS01265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNR01_RS01270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNR01_RS01280	COG2204	response regulator
FNR01_RS01285	COG0527	aspartate kinase activity
FNR01_RS01285	COG0460	homoserine dehydrogenase
FNR01_RS01295	COG2942	2-epimerase
FNR01_RS01300	COG2211	Major facilitator Superfamily
FNR01_RS01305	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FNR01_RS01310	COG4124	Belongs to the glycosyl hydrolase 26 family
FNR01_RS01370	COG4206	TonB-dependent receptor
FNR01_RS01370	COG1629	transport
FNR01_RS01375	COG4124	Belongs to the glycosyl hydrolase 26 family
FNR01_RS01390	COG0561	phosphatase activity
FNR01_RS01395	COG4771	TonB-dependent receptor
FNR01_RS01400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNR01_RS01410	COG3458	cephalosporin-C deacetylase activity
FNR01_RS01415	COG0662	Cupin 2, conserved barrel domain protein
FNR01_RS01415	COG2207	Transcriptional regulator
FNR01_RS01420	COG3250	beta-galactosidase activity
FNR01_RS01425	COG3459	Glycosyltransferase 36 associated
FNR01_RS01430	COG0667	Aldo Keto reductase
FNR01_RS01435	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS01450	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS01455	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS01460	COG0737	Belongs to the 5'-nucleotidase family
FNR01_RS01465	COG0737	Belongs to the 5'-nucleotidase family
FNR01_RS01470	COG0335	large ribosomal subunit rRNA binding
FNR01_RS01480	COG1940	carbohydrate kinase activity
FNR01_RS01485	COG1136	(ABC) transporter
FNR01_RS01490	COG1136	(ABC) transporter
FNR01_RS01490	COG0577	efflux transmembrane transporter activity
FNR01_RS01495	COG1136	(ABC) transporter
FNR01_RS01495	COG0577	efflux transmembrane transporter activity
FNR01_RS01500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS01520	COG2996	Protein conserved in bacteria
FNR01_RS01525	COG0039	L-malate dehydrogenase activity
FNR01_RS01545	COG1454	alcohol dehydrogenase
FNR01_RS01550	COG0235	Class ii aldolase
FNR01_RS01560	COG4806	L-rhamnose isomerase
FNR01_RS01565	COG1070	Carbohydrate kinase
FNR01_RS01580	COG0137	argininosuccinate synthase activity
FNR01_RS01590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNR01_RS01595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNR01_RS01600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNR01_RS01605	COG1917	Cupin 2, conserved barrel domain protein
FNR01_RS01605	COG1396	sequence-specific DNA binding
FNR01_RS01610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNR01_RS01640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNR01_RS01650	COG2890	protein-(glutamine-N5) methyltransferase activity
FNR01_RS01655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNR01_RS01655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FNR01_RS01665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNR01_RS01685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FNR01_RS01695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNR01_RS01700	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNR01_RS01730	COG0564	pseudouridine synthase activity
FNR01_RS01740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNR01_RS01745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNR01_RS01750	COG1216	Glycosyl transferase, family 2
FNR01_RS01755	COG2003	Belongs to the UPF0758 family
FNR01_RS01765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNR01_RS01780	COG1785	Belongs to the alkaline phosphatase family
FNR01_RS01785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNR01_RS01790	COG0280	phosphate acetyltransferase
FNR01_RS01800	COG1380	Effector of murein hydrolase LrgA
FNR01_RS01805	COG1346	cytolysis
FNR01_RS01820	COG0312	modulator of DNA gyrase
FNR01_RS01825	COG0312	modulator of DNA gyrase
FNR01_RS01830	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FNR01_RS01835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNR01_RS01840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNR01_RS01850	COG0733	neurotransmitter:sodium symporter activity
FNR01_RS01865	COG1136	(ABC) transporter
FNR01_RS01870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FNR01_RS01875	COG0475	glutathione-regulated potassium exporter activity
FNR01_RS01875	COG0589	response to stress
FNR01_RS01880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNR01_RS01885	COG1649	PFAM Uncharacterised BCR, COG1649
FNR01_RS01890	COG0702	epimerase
FNR01_RS01895	COG1629	transport
FNR01_RS01895	COG4206	TonB-dependent receptor
FNR01_RS01915	COG4206	TonB-dependent receptor
FNR01_RS01915	COG1629	transport
FNR01_RS01920	COG0702	epimerase
FNR01_RS01960	COG3876	Protein conserved in bacteria
FNR01_RS01965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FNR01_RS01995	COG2807	transmembrane transport
FNR01_RS02000	COG3876	Protein conserved in bacteria
FNR01_RS02020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNR01_RS02025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNR01_RS02035	COG0423	glycine-tRNA ligase activity
FNR01_RS02040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNR01_RS02050	COG3250	beta-galactosidase activity
FNR01_RS02055	COG0745	RESPONSE REGULATOR receiver
FNR01_RS02055	COG2205	protein histidine kinase activity
FNR01_RS02055	COG3292	Two component regulator propeller
FNR01_RS02060	COG4771	TonB-dependent receptor
FNR01_RS02065	COG0561	phosphatase activity
FNR01_RS02080	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS02085	COG3250	beta-galactosidase activity
FNR01_RS02090	COG1874	Beta-galactosidase
FNR01_RS02095	COG3250	beta-galactosidase activity
FNR01_RS02105	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS02110	COG3507	Belongs to the glycosyl hydrolase 43 family
FNR01_RS02145	COG1629	transport
FNR01_RS02145	COG4206	TonB-dependent receptor
FNR01_RS02170	COG4771	TonB-dependent receptor
FNR01_RS02175	COG0702	epimerase
FNR01_RS02205	COG2954	triphosphatase activity
FNR01_RS02210	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FNR01_RS02245	COG1629	transport
FNR01_RS02245	COG4206	TonB-dependent receptor
FNR01_RS02250	COG1022	Amp-dependent synthetase and ligase
FNR01_RS02255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNR01_RS02260	COG4942	peptidase
FNR01_RS02275	COG0756	dUTP diphosphatase activity
FNR01_RS02315	COG2001	Belongs to the MraZ family
FNR01_RS02330	COG0768	penicillin binding
FNR01_RS02335	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNR01_RS02340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNR01_RS02345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNR01_RS02350	COG0772	Belongs to the SEDS family
FNR01_RS02355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNR01_RS02360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNR01_RS02370	COG0849	cell division
FNR01_RS02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNR01_RS02380	COG1610	YqeY-like protein
FNR01_RS02385	COG1381	Involved in DNA repair and RecF pathway recombination
FNR01_RS02395	COG0268	Binds directly to 16S ribosomal RNA
FNR01_RS02400	COG0187	DNA topoisomerase II activity
FNR01_RS02410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNR01_RS02420	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNR01_RS02435	COG4771	TonB-dependent receptor
FNR01_RS02440	COG0702	epimerase
FNR01_RS02445	COG3408	Glycogen debranching enzyme
FNR01_RS02445	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FNR01_RS02450	COG3250	beta-galactosidase activity
FNR01_RS02460	COG2431	L-lysine efflux transmembrane transporter activity
FNR01_RS02470	COG3408	Glycogen debranching enzyme
FNR01_RS02470	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FNR01_RS02475	COG3426	butyrate kinase activity
FNR01_RS02480	COG0280	phosphate acetyltransferase
FNR01_RS02495	COG2166	iron-sulfur cluster assembly
FNR01_RS02510	COG3655	Transcriptional regulator
FNR01_RS02540	COG1266	CAAX protease self-immunity
FNR01_RS02550	COG0196	riboflavin kinase activity
FNR01_RS02555	COG1011	Hydrolase
FNR01_RS02560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FNR01_RS02565	COG2205	protein histidine kinase activity
FNR01_RS02565	COG2198	Histidine kinase
FNR01_RS02565	COG0784	Response regulator, receiver
FNR01_RS02570	COG1773	rubredoxin
FNR01_RS02575	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNR01_RS02580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNR01_RS02585	COG2205	protein histidine kinase activity
FNR01_RS02590	COG0006	proline dipeptidase activity
FNR01_RS02605	COG0509	glycine decarboxylation via glycine cleavage system
FNR01_RS02610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FNR01_RS02615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNR01_RS02645	COG3119	arylsulfatase activity
FNR01_RS02665	COG0702	epimerase
FNR01_RS02670	COG4771	TonB-dependent receptor
FNR01_RS02685	COG3119	arylsulfatase activity
FNR01_RS02690	COG3250	beta-galactosidase activity
FNR01_RS02710	COG0793	Belongs to the peptidase S41A family
FNR01_RS02715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNR01_RS02740	COG0483	inositol monophosphate 1-phosphatase activity
FNR01_RS02760	COG2816	NAD+ diphosphatase activity
FNR01_RS02785	COG0018	arginyl-trna synthetase
FNR01_RS02810	COG0339	signal peptide processing
FNR01_RS02815	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FNR01_RS02830	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNR01_RS02830	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNR01_RS02835	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNR01_RS02840	COG4206	TonB-dependent receptor
FNR01_RS02840	COG1629	transport
FNR01_RS02870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNR01_RS02875	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNR01_RS02885	COG1217	gtp-binding protein TYPA
FNR01_RS02890	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FNR01_RS02915	COG0318	PFAM AMP-dependent synthetase and ligase
FNR01_RS02920	COG1854	S-ribosylhomocysteine lyase activity
FNR01_RS02925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNR01_RS02935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNR01_RS02940	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNR01_RS02955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNR01_RS02960	COG4974	Belongs to the 'phage' integrase family
FNR01_RS02975	COG0606	chelatase, subunit chli
FNR01_RS02985	COG3594	Acyltransferase
FNR01_RS02995	COG3537	Alpha-1,2-mannosidase
FNR01_RS03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNR01_RS03020	COG4771	TonB-dependent receptor
FNR01_RS03035	COG3594	Acyltransferase
FNR01_RS03065	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNR01_RS03065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNR01_RS03085	COG3475	LICD family
FNR01_RS03095	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS03105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FNR01_RS03110	COG0545	Peptidyl-prolyl cis-trans isomerase
FNR01_RS03115	COG0545	Peptidyl-prolyl cis-trans isomerase
FNR01_RS03120	COG1522	sequence-specific DNA binding
FNR01_RS03185	COG1196	nuclear chromosome segregation
FNR01_RS03285	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
FNR01_RS03335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNR01_RS03340	COG0793	Belongs to the peptidase S41A family
FNR01_RS03340	COG3409	Peptidoglycan-binding domain 1 protein
FNR01_RS03345	COG0671	phosphoesterase, PA-phosphatase related
FNR01_RS03360	COG1053	succinate dehydrogenase
FNR01_RS03365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FNR01_RS03405	COG0826	peptidase U32
FNR01_RS03410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNR01_RS03435	COG0557	exoribonuclease II activity
FNR01_RS03445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNR01_RS03450	COG1045	serine acetyltransferase
FNR01_RS03455	COG0116	Belongs to the methyltransferase superfamily
FNR01_RS03455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNR01_RS03460	COG1506	peptidase
FNR01_RS03460	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS03465	COG0151	Belongs to the GarS family
FNR01_RS03475	COG1238	metal cluster binding
FNR01_RS03505	COG2942	2-epimerase
FNR01_RS03515	COG1629	transport
FNR01_RS03515	COG4206	TonB-dependent receptor
FNR01_RS03520	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS03525	COG3292	Two component regulator propeller
FNR01_RS03525	COG0745	RESPONSE REGULATOR receiver
FNR01_RS03525	COG2205	protein histidine kinase activity
FNR01_RS03530	COG3291	Pkd domain containing protein
FNR01_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS03605	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FNR01_RS03630	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNR01_RS03665	COG4974	Belongs to the 'phage' integrase family
FNR01_RS03670	COG4974	Belongs to the 'phage' integrase family
FNR01_RS03690	COG2433	Pfam Transposase IS66
FNR01_RS03725	COG3292	Two component regulator propeller
FNR01_RS03725	COG0745	RESPONSE REGULATOR receiver
FNR01_RS03725	COG3292	Two component regulator propeller
FNR01_RS03725	COG2205	protein histidine kinase activity
FNR01_RS03725	COG2205	protein histidine kinase activity
FNR01_RS03725	COG0745	RESPONSE REGULATOR receiver
FNR01_RS03790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNR01_RS03795	COG0084	hydrolase, TatD family'
FNR01_RS03800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNR01_RS03805	COG0594	ribonuclease P activity
FNR01_RS03820	COG1611	Belongs to the LOG family
FNR01_RS03830	COG3385	transposase activity
FNR01_RS03930	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNR01_RS03960	COG0784	Response regulator, receiver
FNR01_RS03960	COG2205	protein histidine kinase activity
FNR01_RS03960	COG2198	Histidine kinase
FNR01_RS03960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNR01_RS03965	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNR01_RS03970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNR01_RS03970	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FNR01_RS03975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNR01_RS03980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNR01_RS03985	COG1968	undecaprenyl-diphosphatase activity
FNR01_RS03995	COG2177	Part of the ABC transporter FtsEX involved in
FNR01_RS04000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNR01_RS04010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNR01_RS04020	COG0427	acetyl-CoA hydrolase
FNR01_RS04115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FNR01_RS04130	COG1592	Rubrerythrin
FNR01_RS04135	COG0659	secondary active sulfate transmembrane transporter activity
FNR01_RS04150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNR01_RS04150	COG0731	radical SAM domain protein
FNR01_RS04160	COG1476	TRANSCRIPTIONal
FNR01_RS04180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNR01_RS04185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNR01_RS04190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNR01_RS04195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNR01_RS04200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNR01_RS04205	COG0495	leucyl-tRNA aminoacylation
FNR01_RS04210	COG0697	spore germination
FNR01_RS04220	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS04230	COG1629	transport
FNR01_RS04230	COG4206	TonB-dependent receptor
FNR01_RS04250	COG1609	Transcriptional regulator
FNR01_RS04265	COG0738	Major facilitator superfamily
FNR01_RS04280	COG4771	TonB-dependent receptor
FNR01_RS04310	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS04325	COG1629	transport
FNR01_RS04350	COG0383	alpha-mannosidase activity
FNR01_RS04360	COG5002	protein histidine kinase activity
FNR01_RS04370	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04410	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNR01_RS04415	COG3250	beta-galactosidase activity
FNR01_RS04420	COG3292	Two component regulator propeller
FNR01_RS04420	COG2205	protein histidine kinase activity
FNR01_RS04420	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04425	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS04450	COG1629	transport
FNR01_RS04450	COG4206	TonB-dependent receptor
FNR01_RS04455	COG0702	epimerase
FNR01_RS04475	COG3408	Glycogen debranching enzyme
FNR01_RS04480	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS04485	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS04490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNR01_RS04505	COG0012	GTP binding
FNR01_RS04525	COG1629	transport
FNR01_RS04540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNR01_RS04540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNR01_RS04545	COG0142	geranyltranstransferase activity
FNR01_RS04550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FNR01_RS04555	COG1694	Mazg nucleotide pyrophosphohydrolase
FNR01_RS04560	COG1490	D-aminoacyl-tRNA deacylase activity
FNR01_RS04565	COG0322	excinuclease ABC activity
FNR01_RS04570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNR01_RS04580	COG1629	transport
FNR01_RS04580	COG4206	TonB-dependent receptor
FNR01_RS04595	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04595	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04595	COG2205	protein histidine kinase activity
FNR01_RS04595	COG3292	Two component regulator propeller
FNR01_RS04595	COG3292	Two component regulator propeller
FNR01_RS04595	COG2205	protein histidine kinase activity
FNR01_RS04600	COG4771	TonB-dependent receptor
FNR01_RS04630	COG3408	Glycogen debranching enzyme
FNR01_RS04640	COG2017	converts alpha-aldose to the beta-anomer
FNR01_RS04660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNR01_RS04665	COG2715	membrane protein required for spore maturation
FNR01_RS04670	COG2234	aminopeptidase activity
FNR01_RS04685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNR01_RS04690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNR01_RS04700	COG1629	transport
FNR01_RS04700	COG4206	TonB-dependent receptor
FNR01_RS04705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNR01_RS04715	COG2255	four-way junction helicase activity
FNR01_RS04725	COG3645	SOS response
FNR01_RS04735	COG3591	Belongs to the peptidase S1B family
FNR01_RS04740	COG3634	alkyl hydroperoxide reductase activity
FNR01_RS04750	COG0583	DNA-binding transcription factor activity
FNR01_RS04755	COG0783	Belongs to the Dps family
FNR01_RS04760	COG0513	Belongs to the DEAD box helicase family
FNR01_RS04785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNR01_RS04790	COG0517	IMP dehydrogenase activity
FNR01_RS04790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FNR01_RS04795	COG0612	Peptidase, M16
FNR01_RS04800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FNR01_RS04805	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNR01_RS04820	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNR01_RS04825	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS04830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FNR01_RS04835	COG1312	Catalyzes the dehydration of D-mannonate
FNR01_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS04855	COG0681	Belongs to the peptidase S26 family
FNR01_RS04865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNR01_RS04890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNR01_RS04900	COG5492	domain, Protein
FNR01_RS04915	COG4771	TonB-dependent receptor
FNR01_RS04925	COG3119	arylsulfatase activity
FNR01_RS04930	COG3292	Two component regulator propeller
FNR01_RS04930	COG2205	protein histidine kinase activity
FNR01_RS04930	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04930	COG0745	RESPONSE REGULATOR receiver
FNR01_RS04930	COG2205	protein histidine kinase activity
FNR01_RS04930	COG3292	Two component regulator propeller
FNR01_RS04955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNR01_RS04970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS04990	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FNR01_RS04995	COG3119	arylsulfatase activity
FNR01_RS05010	COG0482	sulfurtransferase activity
FNR01_RS05025	COG0205	6-phosphofructokinase activity
FNR01_RS05030	COG0571	ribonuclease III activity
FNR01_RS05035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNR01_RS05040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNR01_RS05045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNR01_RS05050	COG3083	sulfuric ester hydrolase activity
FNR01_RS05055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNR01_RS05065	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS05070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNR01_RS05075	COG4750	Nucleotidyl transferase
FNR01_RS05080	COG3475	LICD family
FNR01_RS05095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FNR01_RS05095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FNR01_RS05100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FNR01_RS05105	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FNR01_RS05115	COG1368	sulfuric ester hydrolase activity
FNR01_RS05125	COG1216	Glycosyl transferase, family 2
FNR01_RS05125	COG1442	glycosyl transferase family 8
FNR01_RS05130	COG3754	Rhamnan synthesis protein F
FNR01_RS05155	COG1216	Glycosyl transferase, family 2
FNR01_RS05155	COG1442	glycosyl transferase family 8
FNR01_RS05170	COG3385	transposase activity
FNR01_RS05190	COG1132	(ABC) transporter
FNR01_RS05195	COG0673	inositol 2-dehydrogenase activity
FNR01_RS05200	COG0673	inositol 2-dehydrogenase activity
FNR01_RS05215	COG3341	Caulimovirus viroplasmin
FNR01_RS05215	COG0328	RNA-DNA hybrid ribonuclease activity
FNR01_RS05225	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNR01_RS05230	COG1166	arginine decarboxylase activity
FNR01_RS05235	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNR01_RS05240	COG1595	DNA-templated transcription, initiation
FNR01_RS05265	COG2205	protein histidine kinase activity
FNR01_RS05265	COG0745	RESPONSE REGULATOR receiver
FNR01_RS05265	COG3292	Two component regulator propeller
FNR01_RS05270	COG2272	Belongs to the type-B carboxylesterase lipase family
FNR01_RS05275	COG4771	TonB-dependent receptor
FNR01_RS05280	COG0702	epimerase
FNR01_RS05285	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS05290	COG3693	PFAM glycoside hydrolase, family 10
FNR01_RS05290	COG2382	esterase
FNR01_RS05290	COG3507	Belongs to the glycosyl hydrolase 43 family
FNR01_RS05295	COG2382	esterase
FNR01_RS05300	COG2382	esterase
FNR01_RS05305	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS05310	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS05315	COG0779	Required for maturation of 30S ribosomal subunits
FNR01_RS05320	COG0195	Participates in both transcription termination and antitermination
FNR01_RS05325	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNR01_RS05335	COG0719	Fe-S assembly protein
FNR01_RS05340	COG0396	ATPase activity
FNR01_RS05345	COG0719	Fe-S assembly protein
FNR01_RS05350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNR01_RS05355	COG0393	Putative heavy-metal-binding
FNR01_RS05365	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNR01_RS05375	COG4206	TonB-dependent receptor
FNR01_RS05375	COG1629	transport
FNR01_RS05390	COG1185	polyribonucleotide nucleotidyltransferase activity
FNR01_RS05400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNR01_RS05405	COG0537	adenosine 5'-monophosphoramidase activity
FNR01_RS05410	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNR01_RS05410	COG0662	Cupin 2, conserved barrel domain protein
FNR01_RS05435	COG4771	TonB-dependent receptor
FNR01_RS05455	COG3507	Belongs to the glycosyl hydrolase 43 family
FNR01_RS05460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FNR01_RS05465	COG3292	Two component regulator propeller
FNR01_RS05465	COG2205	protein histidine kinase activity
FNR01_RS05465	COG0745	RESPONSE REGULATOR receiver
FNR01_RS05470	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS05475	COG3250	beta-galactosidase activity
FNR01_RS05480	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS05500	COG2096	Adenosyltransferase
FNR01_RS05510	COG0514	ATP-dependent DNA helicase (RecQ)
FNR01_RS05515	COG3189	MarR family transcriptional regulator
FNR01_RS05560	COG3550	peptidyl-serine autophosphorylation
FNR01_RS05630	COG3385	transposase activity
FNR01_RS05650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FNR01_RS05655	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FNR01_RS05695	COG4974	Belongs to the 'phage' integrase family
FNR01_RS05700	COG4974	Belongs to the 'phage' integrase family
FNR01_RS05750	COG0443	Heat shock 70 kDa protein
FNR01_RS05790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNR01_RS05800	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FNR01_RS05805	COG0006	proline dipeptidase activity
FNR01_RS05810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNR01_RS05815	COG4974	Belongs to the 'phage' integrase family
FNR01_RS05860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNR01_RS05865	COG0081	regulation of translation
FNR01_RS05870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNR01_RS05875	COG0222	ribosome binding
FNR01_RS05880	COG0085	RNA polymerase activity
FNR01_RS05885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNR01_RS05895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNR01_RS05900	COG0049	tRNA binding
FNR01_RS05905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNR01_RS05910	COG0051	transcription antitermination factor activity, RNA binding
FNR01_RS05915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNR01_RS05920	COG0088	Forms part of the polypeptide exit tunnel
FNR01_RS05925	COG0089	rRNA binding
FNR01_RS05930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNR01_RS05935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FNR01_RS05940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNR01_RS05945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNR01_RS05950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNR01_RS05955	COG0255	Belongs to the universal ribosomal protein uL29 family
FNR01_RS05960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNR01_RS05965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNR01_RS05970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNR01_RS05975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNR01_RS05980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNR01_RS05985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNR01_RS05990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNR01_RS05995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNR01_RS06000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNR01_RS06005	COG1841	ribosomal large subunit assembly
FNR01_RS06010	COG0200	Binds to the 23S rRNA
FNR01_RS06025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNR01_RS06030	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNR01_RS06035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNR01_RS06040	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNR01_RS06045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNR01_RS06050	COG0202	RNA polymerase activity
FNR01_RS06055	COG0203	ribosomal protein L17
FNR01_RS06070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNR01_RS06085	COG2431	L-lysine efflux transmembrane transporter activity
FNR01_RS06105	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FNR01_RS06115	COG1228	amidohydrolase
FNR01_RS06125	COG2986	histidine ammonia-lyase
FNR01_RS06130	COG1309	transcriptional regulator
FNR01_RS06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS06165	COG1696	Membrane protein involved in D-alanine export
FNR01_RS06170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNR01_RS06180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS06275	COG1131	(ABC) transporter
FNR01_RS06295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FNR01_RS06315	COG0564	pseudouridine synthase activity
FNR01_RS06490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNR01_RS06505	COG1538	Outer membrane efflux protein
FNR01_RS06515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNR01_RS06560	COG4372	Transposase
FNR01_RS06580	COG0500	methyltransferase
FNR01_RS06620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNR01_RS06640	COG0739	heme binding
FNR01_RS06705	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNR01_RS06710	COG1705	Flagellar rod assembly protein muramidase FlgJ
FNR01_RS06740	COG1373	ATPase (AAA superfamily
FNR01_RS06795	COG3118	belongs to the thioredoxin family
FNR01_RS06855	COG1192	Involved in chromosome partitioning
FNR01_RS06860	COG0629	single-stranded DNA binding
FNR01_RS06930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNR01_RS06935	COG0612	Peptidase, M16
FNR01_RS06940	COG0534	Mate efflux family protein
FNR01_RS06945	COG0784	Response regulator, receiver
FNR01_RS06945	COG2205	protein histidine kinase activity
FNR01_RS06990	COG0488	(ABC) transporter
FNR01_RS06995	COG3590	peptidase
FNR01_RS07000	COG0138	bifunctional purine biosynthesis protein purh
FNR01_RS07010	COG1792	Involved in formation and maintenance of cell shape
FNR01_RS07025	COG0772	Belongs to the SEDS family
FNR01_RS07035	COG1774	PSP1 C-terminal conserved region
FNR01_RS07040	COG0470	DNA polymerase III
FNR01_RS07045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FNR01_RS07060	COG0826	peptidase U32
FNR01_RS07075	COG1487	ribonuclease activity
FNR01_RS07080	COG4771	TonB-dependent receptor
FNR01_RS07090	COG3292	Two component regulator propeller
FNR01_RS07090	COG0745	RESPONSE REGULATOR receiver
FNR01_RS07090	COG3292	Two component regulator propeller
FNR01_RS07090	COG2205	protein histidine kinase activity
FNR01_RS07090	COG0745	RESPONSE REGULATOR receiver
FNR01_RS07090	COG2205	protein histidine kinase activity
FNR01_RS07095	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FNR01_RS07100	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FNR01_RS07105	COG0288	reversible hydration of carbon dioxide
FNR01_RS07110	COG0252	asparaginase activity
FNR01_RS07120	COG0460	homoserine dehydrogenase
FNR01_RS07120	COG0527	aspartate kinase activity
FNR01_RS07125	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FNR01_RS07130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FNR01_RS07210	COG0456	acetyltransferase
FNR01_RS07275	COG0551	DNA topoisomerase type I activity
FNR01_RS07275	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNR01_RS07285	COG1309	transcriptional regulator
FNR01_RS07290	COG4974	Belongs to the 'phage' integrase family
FNR01_RS07550	COG4974	Belongs to the 'phage' integrase family
FNR01_RS07560	COG0628	permease
FNR01_RS07565	COG1435	thymidine kinase activity
FNR01_RS07575	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNR01_RS07590	COG2095	MarC family integral membrane protein
FNR01_RS07600	COG1629	transport
FNR01_RS07600	COG4206	TonB-dependent receptor
FNR01_RS07605	COG3385	transposase activity
FNR01_RS07610	COG1373	ATPase (AAA superfamily
FNR01_RS07625	COG4771	TonB-dependent receptor
FNR01_RS07640	COG1629	transport
FNR01_RS07645	COG4974	Belongs to the 'phage' integrase family
FNR01_RS07650	COG4771	TonB-dependent receptor
FNR01_RS07665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNR01_RS07675	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FNR01_RS07675	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FNR01_RS07690	COG0531	amino acid
FNR01_RS07700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNR01_RS07705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS07710	COG1162	GTPase activity
FNR01_RS07715	COG0233	cytoplasmic translational termination
FNR01_RS07720	COG0528	UMP kinase activity
FNR01_RS07730	COG0697	spore germination
FNR01_RS07735	COG2217	Heavy metal translocating P-type atpase
FNR01_RS07740	COG0534	Mate efflux family protein
FNR01_RS07750	COG3292	Two component regulator propeller
FNR01_RS07750	COG0745	RESPONSE REGULATOR receiver
FNR01_RS07750	COG2205	protein histidine kinase activity
FNR01_RS07760	COG4771	TonB-dependent receptor
FNR01_RS07765	COG0702	epimerase
FNR01_RS07775	COG3250	beta-galactosidase activity
FNR01_RS07790	COG0792	nuclease activity
FNR01_RS07815	COG1183	phosphatidylcholine synthase activity
FNR01_RS07820	COG0688	phosphatidylethanolamine metabolic process
FNR01_RS07855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNR01_RS07865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNR01_RS07875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNR01_RS07885	COG2985	domain, Protein
FNR01_RS07885	COG0490	domain, Protein
FNR01_RS07890	COG1506	peptidase
FNR01_RS07890	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS07890	COG4946	Tricorn protease homolog
FNR01_RS07950	COG2315	Protein conserved in bacteria
FNR01_RS07955	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNR01_RS07970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNR01_RS07975	COG0742	ribosomal rna small subunit methyltransferase
FNR01_RS08005	COG0739	heme binding
FNR01_RS08020	COG1705	Flagellar rod assembly protein muramidase FlgJ
FNR01_RS08020	COG1388	LysM domain
FNR01_RS08030	COG1475	DNA binding
FNR01_RS08035	COG1192	Involved in chromosome partitioning
FNR01_RS08050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FNR01_RS08055	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNR01_RS08070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNR01_RS08085	COG0138	bifunctional purine biosynthesis protein purh
FNR01_RS08090	COG1196	nuclear chromosome segregation
FNR01_RS08095	COG2239	Acts as a magnesium transporter
FNR01_RS08100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNR01_RS08110	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNR01_RS08140	COG1119	ATPase activity
FNR01_RS08150	COG0668	transmembrane transport
FNR01_RS08170	COG4412	M6 family metalloprotease domain protein
FNR01_RS08170	COG1404	Belongs to the peptidase S8 family
FNR01_RS08175	COG5002	protein histidine kinase activity
FNR01_RS08175	COG0784	Response regulator, receiver
FNR01_RS08175	COG2205	protein histidine kinase activity
FNR01_RS08185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNR01_RS08190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNR01_RS08195	COG0713	ATP synthesis coupled electron transport
FNR01_RS08200	COG0839	Belongs to the complex I subunit 6 family
FNR01_RS08205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNR01_RS08210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNR01_RS08215	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNR01_RS08215	COG0649	NAD binding
FNR01_RS08220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNR01_RS08225	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNR01_RS08235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNR01_RS08240	COG0569	domain protein
FNR01_RS08245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNR01_RS08260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNR01_RS08265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNR01_RS08270	COG0805	protein transport
FNR01_RS08285	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FNR01_RS08290	COG3775	system Galactitol-specific IIC component
FNR01_RS08305	COG4771	TonB-dependent receptor
FNR01_RS08320	COG0546	phosphoglycolate phosphatase activity
FNR01_RS08330	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNR01_RS08335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNR01_RS08345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNR01_RS08350	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS08350	COG1506	peptidase
FNR01_RS08355	COG4821	SIS domain
FNR01_RS08360	COG2814	Major facilitator Superfamily
FNR01_RS08370	COG1242	4 iron, 4 sulfur cluster binding
FNR01_RS08380	COG0363	glucosamine-6-phosphate deaminase activity
FNR01_RS08420	COG0681	Belongs to the peptidase S26 family
FNR01_RS08530	COG0628	permease
FNR01_RS08535	COG0009	L-threonylcarbamoyladenylate synthase
FNR01_RS08540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNR01_RS08545	COG0561	phosphatase activity
FNR01_RS08560	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FNR01_RS08575	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS08585	COG1073	alpha beta
FNR01_RS08600	COG3487	Iron-regulated protein
FNR01_RS08625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNR01_RS08625	COG1333	cytochrome c biogenesis protein
FNR01_RS08650	COG1629	transport
FNR01_RS08650	COG4206	TonB-dependent receptor
FNR01_RS08665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNR01_RS08675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNR01_RS08680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FNR01_RS08680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNR01_RS08685	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNR01_RS08690	COG1078	dGTPase activity
FNR01_RS08695	COG0284	orotidine-5'-phosphate decarboxylase activity
FNR01_RS08700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNR01_RS08705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNR01_RS08710	COG1704	LemA family
FNR01_RS08725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNR01_RS08735	COG2226	methyltransferase
FNR01_RS08740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNR01_RS08745	COG1702	phosphate starvation-inducible protein PhoH
FNR01_RS08760	COG1496	oxidoreductase activity
FNR01_RS08765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNR01_RS08770	COG0563	adenylate kinase activity
FNR01_RS08775	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FNR01_RS08785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNR01_RS08785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNR01_RS08800	COG0101	tRNA pseudouridine synthase activity
FNR01_RS08810	COG1956	GAF domain-containing protein
FNR01_RS08820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FNR01_RS08830	COG2140	Oxalate decarboxylase
FNR01_RS08850	COG2814	Major facilitator Superfamily
FNR01_RS08860	COG4771	TonB-dependent receptor
FNR01_RS08865	COG0702	epimerase
FNR01_RS08880	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS08885	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNR01_RS08900	COG2755	lipolytic protein G-D-S-L family
FNR01_RS08900	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNR01_RS08925	COG4974	Belongs to the 'phage' integrase family
FNR01_RS08940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FNR01_RS08965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FNR01_RS08970	COG0793	Belongs to the peptidase S41A family
FNR01_RS08975	COG2131	deaminase
FNR01_RS08985	COG0339	signal peptide processing
FNR01_RS08995	COG1970	mechanosensitive ion channel activity
FNR01_RS09005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNR01_RS09005	COG0519	Catalyzes the synthesis of GMP from XMP
FNR01_RS09010	COG0519	Catalyzes the synthesis of GMP from XMP
FNR01_RS09035	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS09050	COG0297	glycogen (starch) synthase activity
FNR01_RS09055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FNR01_RS09060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FNR01_RS09070	COG0543	2 iron, 2 sulfur cluster binding
FNR01_RS09085	COG3279	Response regulator of the LytR AlgR family
FNR01_RS09090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNR01_RS09095	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNR01_RS09100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNR01_RS09120	COG1191	sigma factor activity
FNR01_RS09130	COG3537	Alpha-1,2-mannosidase
FNR01_RS09135	COG4771	TonB-dependent receptor
FNR01_RS09160	COG3537	Alpha-1,2-mannosidase
FNR01_RS09170	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FNR01_RS09175	COG3537	Alpha-1,2-mannosidase
FNR01_RS09190	COG0791	NLP P60 protein
FNR01_RS09205	COG0612	Peptidase, M16
FNR01_RS09210	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FNR01_RS09215	COG1597	lipid kinase activity
FNR01_RS09220	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNR01_RS09230	COG0534	Mate efflux family protein
FNR01_RS09240	COG3973	AAA domain
FNR01_RS09265	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FNR01_RS09270	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNR01_RS09275	COG1663	tetraacyldisaccharide 4'-kinase activity
FNR01_RS09280	COG0616	signal peptide processing
FNR01_RS09320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNR01_RS09325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNR01_RS09330	COG0066	3-isopropylmalate dehydratase activity
FNR01_RS09350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNR01_RS09360	COG0514	ATP-dependent DNA helicase (RecQ)
FNR01_RS09380	COG0735	belongs to the Fur family
FNR01_RS09385	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNR01_RS09405	COG0124	histidyl-tRNA synthetase
FNR01_RS09420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNR01_RS09425	COG0459	protein refolding
FNR01_RS09445	COG0484	heat shock protein binding
FNR01_RS09465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNR01_RS09470	COG2086	electron transfer activity
FNR01_RS09490	COG4771	TonB-dependent receptor
FNR01_RS09500	COG1621	beta-fructofuranosidase activity
FNR01_RS09505	COG1621	beta-fructofuranosidase activity
FNR01_RS09515	COG1621	beta-fructofuranosidase activity
FNR01_RS09520	COG1621	beta-fructofuranosidase activity
FNR01_RS09540	COG0745	RESPONSE REGULATOR receiver
FNR01_RS09540	COG2205	protein histidine kinase activity
FNR01_RS09540	COG3292	Two component regulator propeller
FNR01_RS09565	COG1649	PFAM Uncharacterised BCR, COG1649
FNR01_RS09570	COG1966	Carbon starvation protein
FNR01_RS09610	COG0784	Response regulator, receiver
FNR01_RS09610	COG5002	protein histidine kinase activity
FNR01_RS09615	COG1649	PFAM Uncharacterised BCR, COG1649
FNR01_RS09665	COG0010	Belongs to the arginase family
FNR01_RS09670	COG0058	SHG alpha-glucan phosphorylase activity
FNR01_RS09675	COG4651	solute:proton antiporter activity
FNR01_RS09675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNR01_RS09680	COG0205	6-phosphofructokinase activity
FNR01_RS09695	COG0588	phosphoglycerate mutase activity
FNR01_RS09700	COG1830	Aldolase
FNR01_RS09765	COG0667	Aldo Keto reductase
FNR01_RS09780	COG2706	6-phosphogluconolactonase activity
FNR01_RS09785	COG2207	Transcriptional regulator
FNR01_RS09825	COG0673	inositol 2-dehydrogenase activity
FNR01_RS09840	COG4206	TonB-dependent receptor
FNR01_RS09840	COG1629	transport
FNR01_RS09880	COG4974	Belongs to the 'phage' integrase family
FNR01_RS09885	COG3292	Two component regulator propeller
FNR01_RS09885	COG2205	protein histidine kinase activity
FNR01_RS09885	COG0745	RESPONSE REGULATOR receiver
FNR01_RS09900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNR01_RS09905	COG1280	lysine exporter protein (LysE YggA)
FNR01_RS09920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNR01_RS09970	COG0511	ligase activity, forming carbon-carbon bonds
FNR01_RS09990	COG1629	transport
FNR01_RS09995	COG0702	epimerase
FNR01_RS10005	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS10025	COG3537	Alpha-1,2-mannosidase
FNR01_RS10035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNR01_RS10040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS10045	COG1554	hydrolase, family 65, central catalytic
FNR01_RS10055	COG1609	Transcriptional regulator
FNR01_RS10065	COG3250	beta-galactosidase activity
FNR01_RS10070	COG1629	transport
FNR01_RS10070	COG4206	TonB-dependent receptor
FNR01_RS10075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNR01_RS10110	COG4974	Belongs to the 'phage' integrase family
FNR01_RS10135	COG0778	Nitroreductase
FNR01_RS10150	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FNR01_RS10155	COG0424	maF-like protein
FNR01_RS10170	COG0126	phosphoglycerate kinase activity
FNR01_RS10175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FNR01_RS10185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNR01_RS10195	COG1629	transport
FNR01_RS10205	COG2223	nitrite transmembrane transporter activity
FNR01_RS10225	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNR01_RS10230	COG1523	belongs to the glycosyl hydrolase 13 family
FNR01_RS10235	COG1119	ATPase activity
FNR01_RS10250	COG0671	phosphoesterase, PA-phosphatase related
FNR01_RS10270	COG0745	RESPONSE REGULATOR receiver
FNR01_RS10275	COG0668	transmembrane transport
FNR01_RS10285	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNR01_RS10300	COG3142	Participates in the control of copper homeostasis
FNR01_RS10305	COG1418	mRNA catabolic process
FNR01_RS10340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNR01_RS10345	COG2832	Protein of unknown function (DUF454)
FNR01_RS10350	COG0351	phosphomethylpyrimidine kinase
FNR01_RS10365	COG0602	queuosine metabolic process
FNR01_RS10380	COG1509	lysine 2,3-aminomutase activity
FNR01_RS10390	COG1115	amino acid carrier protein
FNR01_RS10415	COG1285	pathogenesis
FNR01_RS10420	COG1388	LysM domain
FNR01_RS10420	COG0741	lytic transglycosylase activity
FNR01_RS10435	COG5002	protein histidine kinase activity
FNR01_RS10435	COG0784	Response regulator, receiver
FNR01_RS10435	COG2205	protein histidine kinase activity
FNR01_RS10490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FNR01_RS10495	COG0346	lactoylglutathione lyase activity
FNR01_RS10500	COG1247	-acetyltransferase
FNR01_RS10505	COG0564	pseudouridine synthase activity
FNR01_RS10515	COG5002	protein histidine kinase activity
FNR01_RS10515	COG2205	protein histidine kinase activity
FNR01_RS10515	COG0784	Response regulator, receiver
FNR01_RS10525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FNR01_RS10530	COG0542	response to heat
FNR01_RS10535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNR01_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS10570	COG1253	flavin adenine dinucleotide binding
FNR01_RS10610	COG1757	Na H antiporter
FNR01_RS10615	COG2814	Major facilitator Superfamily
FNR01_RS10620	COG0745	RESPONSE REGULATOR receiver
FNR01_RS10765	COG4974	Belongs to the 'phage' integrase family
FNR01_RS10785	COG4864	UPF0365 protein
FNR01_RS10800	COG0037	tRNA processing
FNR01_RS10815	COG1971	Probably functions as a manganese efflux pump
FNR01_RS10830	COG0463	Glycosyl transferase, family 2
FNR01_RS10855	COG4206	TonB-dependent receptor
FNR01_RS10855	COG1629	transport
FNR01_RS10860	COG0702	epimerase
FNR01_RS10885	COG0148	phosphopyruvate hydratase activity
FNR01_RS10895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNR01_RS10905	COG1082	Xylose isomerase domain protein TIM barrel
FNR01_RS10920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNR01_RS10925	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNR01_RS10930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNR01_RS10940	COG0254	rRNA binding
FNR01_RS10950	COG0191	fructose-bisphosphate aldolase activity
FNR01_RS10955	COG0366	Alpha amylase catalytic
FNR01_RS10965	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FNR01_RS10970	COG0511	ligase activity, forming carbon-carbon bonds
FNR01_RS10980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNR01_RS10995	COG2204	response regulator
FNR01_RS11000	COG4191	Histidine kinase
FNR01_RS11035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNR01_RS11045	COG1979	alcohol dehydrogenase
FNR01_RS11050	COG1530	ribonuclease E activity
FNR01_RS11055	COG0776	regulation of translation
FNR01_RS11065	COG0629	single-stranded DNA binding
FNR01_RS11080	COG3033	Beta-eliminating lyase
FNR01_RS11085	COG5002	protein histidine kinase activity
FNR01_RS11090	COG0745	RESPONSE REGULATOR receiver
FNR01_RS11100	COG4771	TonB-dependent receptor
FNR01_RS11115	COG0488	(ABC) transporter
FNR01_RS11135	COG3591	Belongs to the peptidase S1B family
FNR01_RS11140	COG3591	Belongs to the peptidase S1B family
FNR01_RS11145	COG0641	radical SAM
FNR01_RS11160	COG1408	metallophosphoesterase
FNR01_RS11175	COG1410	methionine synthase
FNR01_RS11175	COG0646	methionine synthase
FNR01_RS11180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNR01_RS11185	COG0463	Glycosyl transferase, family 2
FNR01_RS11190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNR01_RS11200	COG1032	radical SAM domain protein
FNR01_RS11225	COG0363	glucosamine-6-phosphate deaminase activity
FNR01_RS11235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNR01_RS11280	COG3757	hydrolase, family 25
FNR01_RS11285	COG2264	protein methyltransferase activity
FNR01_RS11325	COG1592	Rubrerythrin
FNR01_RS11325	COG1773	rubredoxin
FNR01_RS11335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNR01_RS11335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FNR01_RS11340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNR01_RS11380	COG0698	ribose 5-phosphate isomerase
FNR01_RS11395	COG1070	Carbohydrate kinase
FNR01_RS11400	COG2160	L-arabinose isomerase activity
FNR01_RS11425	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FNR01_RS11440	COG1482	cell wall glycoprotein biosynthetic process
FNR01_RS11460	COG0513	Belongs to the DEAD box helicase family
FNR01_RS11475	COG1218	3'(2'),5'-bisphosphate nucleotidase
FNR01_RS11480	COG0471	metal ion transport
FNR01_RS11480	COG3273	potassium ion transport
FNR01_RS11485	COG0529	Catalyzes the synthesis of activated sulfate
FNR01_RS11490	COG0175	sulfate reduction
FNR01_RS11495	COG2895	sulfate adenylyltransferase (ATP) activity
FNR01_RS11530	COG3385	transposase activity
FNR01_RS11565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNR01_RS11570	COG0242	peptide deformylase activity
FNR01_RS11580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNR01_RS11585	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNR01_RS11590	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNR01_RS11595	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNR01_RS11600	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FNR01_RS11605	COG0674	pyruvate-flavodoxin oxidoreductase activity
FNR01_RS11605	COG1013	pyruvate-flavodoxin oxidoreductase activity
FNR01_RS11605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FNR01_RS11605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FNR01_RS11615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNR01_RS11620	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS11825	COG1940	carbohydrate kinase activity
FNR01_RS11840	COG2942	2-epimerase
FNR01_RS11845	COG4771	TonB-dependent receptor
FNR01_RS11850	COG0702	epimerase
FNR01_RS11865	COG0457	Tetratricopeptide repeat
FNR01_RS11875	COG0484	heat shock protein binding
FNR01_RS11880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNR01_RS11885	COG0488	(ABC) transporter
FNR01_RS11900	COG2183	response to ionizing radiation
FNR01_RS11925	COG4771	TonB-dependent receptor
FNR01_RS11930	COG1917	Cupin 2, conserved barrel domain protein
FNR01_RS11930	COG4977	sequence-specific DNA binding
FNR01_RS11960	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FNR01_RS11965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FNR01_RS11970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNR01_RS11975	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS11995	COG4974	Belongs to the 'phage' integrase family
FNR01_RS12000	COG4974	Belongs to the 'phage' integrase family
FNR01_RS12075	COG1192	Involved in chromosome partitioning
FNR01_RS12110	COG1120	ATPase activity
FNR01_RS12115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNR01_RS12175	COG0534	Mate efflux family protein
FNR01_RS12210	COG0586	Pfam SNARE associated Golgi protein
FNR01_RS12220	COG0306	phosphate transporter
FNR01_RS12230	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FNR01_RS12240	COG3119	arylsulfatase activity
FNR01_RS12245	COG0318	PFAM AMP-dependent synthetase and ligase
FNR01_RS12255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNR01_RS12265	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FNR01_RS12270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FNR01_RS12275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNR01_RS12280	COG0363	glucosamine-6-phosphate deaminase activity
FNR01_RS12290	COG0259	pyridoxamine-phosphate oxidase activity
FNR01_RS12300	COG3279	Response regulator of the LytR AlgR family
FNR01_RS12310	COG0577	efflux transmembrane transporter activity
FNR01_RS12310	COG1136	(ABC) transporter
FNR01_RS12315	COG1136	(ABC) transporter
FNR01_RS12345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNR01_RS12355	COG0534	Mate efflux family protein
FNR01_RS12365	COG1177	transmembrane transport
FNR01_RS12370	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNR01_RS12375	COG3842	ATPase activity
FNR01_RS12380	COG4221	oxidoreductase activity
FNR01_RS12395	COG0488	(ABC) transporter
FNR01_RS12415	COG0513	Belongs to the DEAD box helicase family
FNR01_RS12420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FNR01_RS12425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNR01_RS12445	COG0545	Peptidyl-prolyl cis-trans isomerase
FNR01_RS12455	COG0534	Mate efflux family protein
FNR01_RS12460	COG1929	Belongs to the glycerate kinase type-1 family
FNR01_RS12465	COG1739	Uncharacterized protein family UPF0029
FNR01_RS12475	COG0778	Nitroreductase
FNR01_RS12485	COG1725	Transcriptional regulator
FNR01_RS12495	COG1122	ATPase activity
FNR01_RS12505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNR01_RS12505	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNR01_RS12510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNR01_RS12515	COG0357	Ribosomal RNA small subunit methyltransferase G
FNR01_RS12540	COG2217	Heavy metal translocating P-type atpase
FNR01_RS12550	COG4772	TonB-dependent receptor
FNR01_RS12555	COG0321	lipoyl(octanoyl) transferase activity
FNR01_RS12585	COG1086	Polysaccharide biosynthesis protein
FNR01_RS12590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS12600	COG1216	Glycosyl transferase, family 2
FNR01_RS12600	COG1442	glycosyl transferase family 8
FNR01_RS12605	COG2089	acid synthase
FNR01_RS12610	COG1083	cytidylyl-transferase
FNR01_RS12620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNR01_RS12625	COG0527	aspartate kinase activity
FNR01_RS12630	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNR01_RS12635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNR01_RS12655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS12675	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS12695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNR01_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS12710	COG0318	PFAM AMP-dependent synthetase and ligase
FNR01_RS12730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNR01_RS12735	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNR01_RS12740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNR01_RS12745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS12760	COG0072	phenylalanine-tRNA ligase activity
FNR01_RS12760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNR01_RS12765	COG0217	transcriptional regulatory protein
FNR01_RS12775	COG1914	H( )-stimulated, divalent metal cation uptake system
FNR01_RS12780	COG0708	Exodeoxyribonuclease III
FNR01_RS12795	COG0481	GTPase activity
FNR01_RS12800	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FNR01_RS12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNR01_RS12805	COG2205	protein histidine kinase activity
FNR01_RS12820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNR01_RS12825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNR01_RS12845	COG0612	Peptidase, M16
FNR01_RS12860	COG2205	protein histidine kinase activity
FNR01_RS12860	COG0784	Response regulator, receiver
FNR01_RS12880	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNR01_RS12885	COG1805	sodium ion transport
FNR01_RS12890	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNR01_RS12900	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FNR01_RS12915	COG0024	Methionine aminopeptidase
FNR01_RS12925	COG0420	3'-5' exonuclease activity
FNR01_RS12955	COG2814	Major facilitator Superfamily
FNR01_RS12970	COG0564	pseudouridine synthase activity
FNR01_RS12975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNR01_RS12980	COG0574	Belongs to the PEP-utilizing enzyme family
FNR01_RS12980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNR01_RS12985	COG2205	protein histidine kinase activity
FNR01_RS12985	COG0784	Response regulator, receiver
FNR01_RS12985	COG5002	protein histidine kinase activity
FNR01_RS12990	COG0352	thiamine-phosphate diphosphorylase activity
FNR01_RS13055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNR01_RS13070	COG1678	Uncharacterized ACR, COG1678
FNR01_RS13075	COG4771	TonB-dependent receptor
FNR01_RS13110	COG0110	maltose O-acetyltransferase activity
FNR01_RS13125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FNR01_RS13140	COG0738	Major facilitator superfamily
FNR01_RS13150	COG2059	Chromate
FNR01_RS13160	COG3969	phosphoadenosine phosphosulfate
FNR01_RS13165	COG1475	DNA binding
FNR01_RS13170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNR01_RS13185	COG1074	ATP-dependent DNA helicase activity
FNR01_RS13195	COG0556	nucleotide-excision repair
FNR01_RS13205	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FNR01_RS13235	COG3942	CHAP domain
FNR01_RS13235	COG1388	LysM domain
FNR01_RS13245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNR01_RS13250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FNR01_RS13255	COG3104	oligopeptide transport
FNR01_RS13270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNR01_RS13280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNR01_RS13285	COG1695	Transcriptional regulator
FNR01_RS13320	COG2755	lipolytic protein G-D-S-L family
FNR01_RS13320	COG0657	acetylesterase activity
FNR01_RS13345	COG3059	membrane
FNR01_RS13350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNR01_RS13365	COG1120	ATPase activity
FNR01_RS13370	COG0534	Mate efflux family protein
FNR01_RS13375	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FNR01_RS13385	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FNR01_RS13415	COG4771	TonB-dependent receptor
FNR01_RS13460	COG0439	Biotin carboxylase
FNR01_RS13470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNR01_RS13480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNR01_RS13490	COG1797	cobyrinic acid a,c-diamide synthase activity
FNR01_RS13510	COG2096	Adenosyltransferase
FNR01_RS13515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FNR01_RS13535	COG1492	cobalamin metabolic process
FNR01_RS13545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FNR01_RS13550	COG2205	protein histidine kinase activity
FNR01_RS13550	COG2202	Pas domain
FNR01_RS13555	COG2202	Pas domain
FNR01_RS13555	COG2205	protein histidine kinase activity
FNR01_RS13565	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNR01_RS13570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNR01_RS13585	COG0442	prolyl-tRNA aminoacylation
FNR01_RS13650	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FNR01_RS13660	COG1216	Glycosyl transferase, family 2
FNR01_RS13660	COG0463	Glycosyl transferase, family 2
FNR01_RS13715	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FNR01_RS13735	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNR01_RS13740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNR01_RS13750	COG1506	peptidase
FNR01_RS13750	COG0823	Involved in the tonB-independent uptake of proteins
FNR01_RS13755	COG4974	Belongs to the 'phage' integrase family
FNR01_RS13795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNR01_RS13795	COG0551	DNA topoisomerase type I activity
FNR01_RS13815	COG2205	protein histidine kinase activity
FNR01_RS13815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNR01_RS13815	COG0784	Response regulator, receiver
FNR01_RS13815	COG2198	Histidine kinase
FNR01_RS13945	COG0358	DNA primase activity
FNR01_RS14015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNR01_RS14030	COG0534	Mate efflux family protein
FNR01_RS14040	COG0504	CTP synthase activity
FNR01_RS14065	COG4656	Part of a membrane complex involved in electron transport
FNR01_RS14070	COG4658	electron transport chain
FNR01_RS14075	COG4659	FMN binding
FNR01_RS14080	COG4660	Part of a membrane complex involved in electron transport
FNR01_RS14085	COG4657	Part of a membrane complex involved in electron transport
FNR01_RS14090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FNR01_RS14110	COG0356	it plays a direct role in the translocation of protons across the membrane
FNR01_RS14115	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNR01_RS14120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNR01_RS14125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNR01_RS14130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNR01_RS14135	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNR01_RS14140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNR01_RS14175	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FNR01_RS14180	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNR01_RS14195	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FNR01_RS14200	COG0540	Belongs to the ATCase OTCase family
FNR01_RS14205	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNR01_RS14215	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FNR01_RS14230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FNR01_RS14235	COG2205	protein histidine kinase activity
FNR01_RS14250	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNR01_RS14275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNR01_RS14320	COG0351	phosphomethylpyrimidine kinase
FNR01_RS14325	COG0352	thiamine-phosphate diphosphorylase activity
FNR01_RS14340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FNR01_RS14345	COG2022	thiamine diphosphate biosynthetic process
FNR01_RS14350	COG0352	thiamine-phosphate diphosphorylase activity
FNR01_RS14365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNR01_RS14385	COG2115	Belongs to the xylose isomerase family
FNR01_RS14390	COG0477	Major facilitator Superfamily
FNR01_RS14390	COG2814	Major facilitator Superfamily
FNR01_RS14395	COG3153	acetyltransferase
FNR01_RS14395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNR01_RS14425	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNR01_RS14435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNR01_RS14450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNR01_RS14470	COG1252	NADH dehydrogenase
FNR01_RS14480	COG2194	sulfuric ester hydrolase activity
FNR01_RS14515	COG3387	PFAM Glycoside hydrolase 15-related
FNR01_RS14525	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNR01_RS14535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNR01_RS14550	COG1904	glucuronate isomerase
FNR01_RS14555	COG1609	Transcriptional regulator
FNR01_RS14560	COG3385	transposase activity
FNR01_RS14565	COG0246	Mannitol dehydrogenase
FNR01_RS14600	COG3328	transposase activity
FNR01_RS14605	COG0513	Belongs to the DEAD box helicase family
FNR01_RS14610	COG3830	Belongs to the UPF0237 family
FNR01_RS14610	COG0560	Phosphoserine phosphatase
FNR01_RS14630	COG0343	queuine tRNA-ribosyltransferase activity
FNR01_RS14635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNR01_RS14640	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FNR01_RS14660	COG0501	Belongs to the peptidase M48B family
FNR01_RS14665	COG0156	8-amino-7-oxononanoate synthase activity
FNR01_RS14675	COG1597	lipid kinase activity
FNR01_RS14680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNR01_RS14695	COG2957	Belongs to the agmatine deiminase family
FNR01_RS14705	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNR01_RS14710	COG0390	transport system, permease component
FNR01_RS14725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FNR01_RS14745	COG1538	Outer membrane efflux protein
FNR01_RS14770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNR01_RS14785	COG0543	2 iron, 2 sulfur cluster binding
FNR01_RS14790	COG0167	dihydroorotate dehydrogenase activity
FNR01_RS14795	COG0336	Belongs to the RNA methyltransferase TrmD family
FNR01_RS14800	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNR01_RS14805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNR01_RS14830	COG0542	response to heat
FNR01_RS14835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNR01_RS14875	COG2304	oxidoreductase activity
FNR01_RS14890	COG0714	Associated with various cellular activities
FNR01_RS14905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNR01_RS14910	COG0552	protein localization to endoplasmic reticulum
FNR01_RS14920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNR01_RS14925	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNR01_RS14930	COG1546	Belongs to the CinA family
FNR01_RS14930	COG1058	Belongs to the CinA family
FNR01_RS14935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNR01_RS14945	COG0305	Participates in initiation and elongation during chromosome replication
FNR01_RS14950	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FNR01_RS14960	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FNR01_RS14970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FNR01_RS14975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FNR01_RS14985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FNR01_RS14990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNR01_RS14995	COG0534	Mate efflux family protein
FNR01_RS15005	COG1136	(ABC) transporter
FNR01_RS15005	COG0577	efflux transmembrane transporter activity
FNR01_RS15010	COG1136	(ABC) transporter
FNR01_RS15035	COG3852	Histidine kinase
FNR01_RS15040	COG3263	regulation of cellular component size
FNR01_RS15045	COG0318	PFAM AMP-dependent synthetase and ligase
FNR01_RS15050	COG1082	Xylose isomerase domain protein TIM barrel
FNR01_RS15070	COG0702	epimerase
FNR01_RS15075	COG4771	TonB-dependent receptor
FNR01_RS15090	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNR01_RS15100	COG2755	lipolytic protein G-D-S-L family
FNR01_RS15100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNR01_RS15110	COG0842	Transport permease protein
FNR01_RS15115	COG1131	(ABC) transporter
FNR01_RS15130	COG1917	Cupin 2, conserved barrel domain protein
FNR01_RS15130	COG2207	Transcriptional regulator
FNR01_RS15135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNR01_RS15140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FNR01_RS15145	COG0505	Belongs to the CarA family
FNR01_RS15155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNR01_RS15160	COG0067	glutamate synthase
FNR01_RS15160	COG0069	glutamate synthase activity
FNR01_RS15160	COG0070	glutamate synthase
FNR01_RS15170	COG0367	asparagine synthase
FNR01_RS15190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS15195	COG0110	maltose O-acetyltransferase activity
FNR01_RS15200	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNR01_RS15205	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS15210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FNR01_RS15280	COG0110	maltose O-acetyltransferase activity
FNR01_RS15355	COG0436	Aminotransferase
FNR01_RS15365	COG0347	Belongs to the P(II) protein family
FNR01_RS15370	COG0004	ammonium transporteR
FNR01_RS15395	COG0133	tryptophan synthase activity
FNR01_RS15400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNR01_RS15405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNR01_RS15405	COG0512	Glutamine amidotransferase of anthranilate synthase
FNR01_RS15410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNR01_RS15415	COG0134	indole-3-glycerol-phosphate synthase activity
FNR01_RS15420	COG0135	phosphoribosylanthranilate isomerase activity
FNR01_RS15425	COG0159	tryptophan synthase activity
FNR01_RS15430	COG0252	asparaginase activity
FNR01_RS15440	COG0745	RESPONSE REGULATOR receiver
FNR01_RS15535	COG1215	transferase activity, transferring glycosyl groups
FNR01_RS15540	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS15550	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS15555	COG1216	Glycosyl transferase, family 2
FNR01_RS15560	COG1442	glycosyl transferase family 8
FNR01_RS15560	COG1216	Glycosyl transferase, family 2
FNR01_RS15590	COG3385	transposase activity
FNR01_RS15595	COG1609	Transcriptional regulator
FNR01_RS15600	COG2721	sulfolactate sulfo-lyase activity
FNR01_RS15610	COG0228	four-way junction DNA binding
FNR01_RS15615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNR01_RS15645	COG0588	phosphoglycerate mutase activity
FNR01_RS15655	COG0716	FMN binding
FNR01_RS15660	COG0058	SHG alpha-glucan phosphorylase activity
FNR01_RS15695	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FNR01_RS15740	COG3023	N-Acetylmuramoyl-L-alanine amidase
FNR01_RS15750	COG0582	viral genome integration into host DNA
FNR01_RS15805	COG0305	Participates in initiation and elongation during chromosome replication
FNR01_RS15840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FNR01_RS15840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FNR01_RS15855	COG2226	methyltransferase
FNR01_RS15865	COG1215	transferase activity, transferring glycosyl groups
FNR01_RS15870	COG4591	ABC-type transport system involved in lipoprotein release permease component
FNR01_RS15875	COG0436	Aminotransferase
FNR01_RS15910	COG0577	efflux transmembrane transporter activity
FNR01_RS15925	COG0577	efflux transmembrane transporter activity
FNR01_RS15925	COG1136	(ABC) transporter
FNR01_RS15930	COG1136	(ABC) transporter
FNR01_RS15940	COG0577	efflux transmembrane transporter activity
FNR01_RS15945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNR01_RS15950	COG1705	Flagellar rod assembly protein muramidase FlgJ
FNR01_RS15955	COG0295	cytidine deaminase activity
FNR01_RS15960	COG0488	(ABC) transporter
FNR01_RS15965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FNR01_RS16010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNR01_RS16020	COG0739	heme binding
FNR01_RS16025	COG0686	Belongs to the AlaDH PNT family
FNR01_RS16035	COG0076	glutamate decarboxylase activity
FNR01_RS16040	COG2066	Belongs to the glutaminase family
FNR01_RS16050	COG0531	amino acid
FNR01_RS16075	COG1595	DNA-templated transcription, initiation
FNR01_RS16100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNR01_RS16115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS16120	COG0277	FAD linked oxidase domain protein
FNR01_RS16120	COG0247	lactate metabolic process
FNR01_RS16220	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNR01_RS16235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNR01_RS16240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNR01_RS16250	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS16280	COG0704	Plays a role in the regulation of phosphate uptake
FNR01_RS16285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNR01_RS16290	COG0581	inorganic phosphate transmembrane transporter activity
FNR01_RS16295	COG0573	inorganic phosphate transmembrane transporter activity
FNR01_RS16300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNR01_RS16305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNR01_RS16315	COG0586	Pfam SNARE associated Golgi protein
FNR01_RS16320	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FNR01_RS16335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNR01_RS16345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNR01_RS16360	COG0673	inositol 2-dehydrogenase activity
FNR01_RS16375	COG3754	Rhamnan synthesis protein F
FNR01_RS16380	COG2244	polysaccharide biosynthetic process
FNR01_RS16395	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNR01_RS16420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNR01_RS16425	COG0167	dihydroorotate dehydrogenase activity
FNR01_RS16435	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FNR01_RS16455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNR01_RS16460	COG0497	DNA recombination
FNR01_RS16475	COG0592	DNA-directed DNA polymerase activity
FNR01_RS16490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNR01_RS16490	COG0321	lipoyl(octanoyl) transferase activity
FNR01_RS16510	COG0156	8-amino-7-oxononanoate synthase activity
FNR01_RS16520	COG0019	diaminopimelate decarboxylase activity
FNR01_RS16525	COG0527	aspartate kinase activity
FNR01_RS16530	COG2884	Cell division ATP-binding protein ftsE
FNR01_RS16535	COG0140	phosphoribosyl-ATP diphosphatase activity
FNR01_RS16535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNR01_RS16540	COG0107	imidazoleglycerol-phosphate synthase activity
FNR01_RS16545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNR01_RS16550	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNR01_RS16555	COG0788	formyltetrahydrofolate deformylase activity
FNR01_RS16600	COG0561	phosphatase activity
FNR01_RS16605	COG4753	response regulator
FNR01_RS16605	COG2207	Transcriptional regulator
FNR01_RS16615	COG0714	Associated with various cellular activities
FNR01_RS16650	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNR01_RS16665	COG1151	hydroxylamine reductase activity
FNR01_RS16690	COG0148	phosphopyruvate hydratase activity
FNR01_RS16695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FNR01_RS16700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FNR01_RS16710	COG1629	transport
FNR01_RS16710	COG4206	TonB-dependent receptor
FNR01_RS16715	COG0702	epimerase
FNR01_RS16740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNR01_RS16745	COG1741	Belongs to the pirin family
FNR01_RS16760	COG0346	lactoylglutathione lyase activity
FNR01_RS16790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FNR01_RS16790	COG1918	ferrous iron import across plasma membrane
FNR01_RS16795	COG0037	tRNA processing
FNR01_RS16810	COG3119	arylsulfatase activity
FNR01_RS16815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNR01_RS16820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNR01_RS16835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNR01_RS16845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNR01_RS16870	COG0534	Mate efflux family protein
FNR01_RS16875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNR01_RS16910	COG0551	DNA topoisomerase type I activity
FNR01_RS16910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNR01_RS16945	COG2433	Pfam Transposase IS66
FNR01_RS16960	COG1204	response to ionizing radiation
FNR01_RS17095	COG2003	Belongs to the UPF0758 family
FNR01_RS17105	COG4974	Belongs to the 'phage' integrase family
FNR01_RS17120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FNR01_RS17240	COG1309	transcriptional regulator
FNR01_RS17245	COG4974	Belongs to the 'phage' integrase family
FNR01_RS17345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNR01_RS17345	COG0551	DNA topoisomerase type I activity
FNR01_RS17535	COG4974	Belongs to the 'phage' integrase family
FNR01_RS17545	COG1193	negative regulation of DNA recombination
FNR01_RS17550	COG1760	l-serine dehydratase
FNR01_RS17565	COG5002	protein histidine kinase activity
FNR01_RS17565	COG3850	Histidine kinase
FNR01_RS17570	COG0745	RESPONSE REGULATOR receiver
FNR01_RS17625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FNR01_RS17630	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FNR01_RS17665	COG4139	cobalamin transport
FNR01_RS17685	COG0561	phosphatase activity
FNR01_RS17715	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FNR01_RS17725	COG0732	type I restriction modification DNA specificity domain
FNR01_RS17730	COG4974	Belongs to the 'phage' integrase family
FNR01_RS17740	COG0732	type I restriction modification DNA specificity domain
FNR01_RS17765	COG4974	Belongs to the 'phage' integrase family
FNR01_RS17785	COG0443	Heat shock 70 kDa protein
FNR01_RS17810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNR01_RS17815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNR01_RS17830	COG1595	DNA-templated transcription, initiation
FNR01_RS17850	COG2855	membrane
FNR01_RS17855	COG0583	DNA-binding transcription factor activity
FNR01_RS17865	COG0542	response to heat
FNR01_RS17875	COG0237	dephospho-CoA kinase activity
FNR01_RS17885	COG1862	Preprotein translocase
FNR01_RS17890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNR01_RS17900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FNR01_RS17905	COG0193	aminoacyl-tRNA hydrolase activity
FNR01_RS17910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FNR01_RS17915	COG0673	inositol 2-dehydrogenase activity
FNR01_RS17920	COG4651	solute:proton antiporter activity
FNR01_RS17920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNR01_RS17925	COG0131	Imidazoleglycerol-phosphate dehydratase
FNR01_RS17930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNR01_RS17935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FNR01_RS17940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNR01_RS17975	COG4974	Belongs to the 'phage' integrase family
FNR01_RS18030	COG0202	RNA polymerase activity
FNR01_RS18130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FNR01_RS18145	COG0697	spore germination
FNR01_RS18155	COG0667	Aldo Keto reductase
FNR01_RS18170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNR01_RS18175	COG0805	protein transport
FNR01_RS18220	COG1475	DNA binding
FNR01_RS18240	COG1192	Involved in chromosome partitioning
FNR01_RS18245	COG0629	single-stranded DNA binding
FNR01_RS18310	COG1538	Outer membrane efflux protein
FNR01_RS18315	COG1733	regulation of RNA biosynthetic process
FNR01_RS18320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNR01_RS18360	COG4771	TonB-dependent receptor
FNR01_RS18475	COG0739	heme binding
FNR01_RS18475	COG1196	nuclear chromosome segregation
FNR01_RS18475	COG0741	lytic transglycosylase activity
FNR01_RS18570	COG1132	(ABC) transporter
FNR01_RS18665	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNR01_RS18665	COG2755	lipolytic protein G-D-S-L family
FNR01_RS18720	COG0534	Mate efflux family protein
FNR01_RS18725	COG0776	regulation of translation
FNR01_RS18815	COG4771	TonB-dependent receptor
FNR01_RS18825	COG1595	DNA-templated transcription, initiation
FNR01_RS18830	COG2271	Major facilitator Superfamily
FNR01_RS18840	COG0702	epimerase
FNR01_RS18845	COG1629	transport
FNR01_RS18870	COG4232	protein-disulfide reductase activity
FNR01_RS18880	COG0572	uridine kinase
FNR01_RS18885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNR01_RS18890	COG1410	methionine synthase
FNR01_RS18890	COG0646	methionine synthase
FNR01_RS18895	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNR01_RS18980	COG0110	maltose O-acetyltransferase activity
FNR01_RS19025	COG0534	Mate efflux family protein
FNR01_RS19035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FNR01_RS19040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNR01_RS19055	COG2217	Heavy metal translocating P-type atpase
FNR01_RS19145	COG1472	Belongs to the glycosyl hydrolase 3 family
FNR01_RS19150	COG2706	6-phosphogluconolactonase activity
FNR01_RS19190	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FNR01_RS19200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNR01_RS19210	COG1253	flavin adenine dinucleotide binding
FNR01_RS19240	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FNR01_RS19245	COG0653	protein targeting
FNR01_RS19275	COG0561	phosphatase activity
FNR01_RS19280	COG4206	TonB-dependent receptor
FNR01_RS19280	COG1629	transport
FNR01_RS19315	COG0525	valine-tRNA ligase activity
FNR01_RS19325	COG3956	TIGRFAM MazG family protein
FNR01_RS19340	COG1595	DNA-templated transcription, initiation
FNR01_RS19385	COG0492	ferredoxin-NADP+ reductase activity
FNR01_RS19395	COG1674	ftsk spoiiie
FNR01_RS19430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FNR01_RS19435	COG2211	Major facilitator Superfamily
FNR01_RS19455	COG1136	(ABC) transporter
FNR01_RS19470	COG1501	Belongs to the glycosyl hydrolase 31 family
FNR01_RS19475	COG0490	domain, Protein
FNR01_RS19475	COG0471	metal ion transport
FNR01_RS19490	COG1733	regulation of RNA biosynthetic process
FNR01_RS19510	COG1917	Cupin 2, conserved barrel domain protein
FNR01_RS19510	COG4977	sequence-specific DNA binding
FNR01_RS19520	COG2873	o-acetylhomoserine
FNR01_RS19545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNR01_RS19560	COG0702	epimerase
FNR01_RS19565	COG4771	TonB-dependent receptor
FNR01_RS19580	COG3119	arylsulfatase activity
FNR01_RS19585	COG3537	Alpha-1,2-mannosidase
FNR01_RS19595	COG1940	carbohydrate kinase activity
FNR01_RS19605	COG2188	Transcriptional regulator
FNR01_RS19610	COG0523	cobalamin synthesis protein
FNR01_RS19615	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FNR01_RS19620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FNR01_RS19630	COG0194	GDP metabolic process
FNR01_RS19640	COG1214	PFAM Peptidase M22, glycoprotease
FNR01_RS19650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNR01_RS19655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNR01_RS19665	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FNR01_RS19670	COG0750	zinc metalloprotease
FNR01_RS19675	COG0673	inositol 2-dehydrogenase activity
FNR01_RS19685	COG0632	four-way junction helicase activity
FNR01_RS19695	COG0006	proline dipeptidase activity
FNR01_RS19705	COG1082	Xylose isomerase domain protein TIM barrel
FNR01_RS19750	COG4771	TonB-dependent receptor
FNR01_RS19765	COG0363	glucosamine-6-phosphate deaminase activity
FNR01_RS19770	COG1940	carbohydrate kinase activity
FNR01_RS19775	COG3292	Two component regulator propeller
FNR01_RS19775	COG2205	protein histidine kinase activity
FNR01_RS19775	COG0745	RESPONSE REGULATOR receiver
FNR01_RS19785	COG1408	metallophosphoesterase
FNR01_RS19790	COG1575	Belongs to the MenA family. Type 1 subfamily
FNR01_RS19800	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FNR01_RS19810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNR01_RS19820	COG0617	tRNA 3'-terminal CCA addition
FNR01_RS19830	COG2204	response regulator
FNR01_RS19835	COG0488	(ABC) transporter
FNR01_RS19840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNR01_RS19875	COG4771	TonB-dependent receptor
FNR01_RS19895	COG1595	DNA-templated transcription, initiation
FNR01_RS19910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FNR01_RS19920	COG1522	sequence-specific DNA binding
FNR01_RS19950	COG0811	peptide transport
FNR01_RS19960	COG0084	hydrolase, TatD family'
FNR01_RS19980	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNR01_RS19985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNR01_RS19990	COG0205	6-phosphofructokinase activity
FNR01_RS19995	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS20010	COG0372	Belongs to the citrate synthase family
FNR01_RS20015	COG0538	isocitrate dehydrogenase activity
FNR01_RS20025	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FNR01_RS20030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNR01_RS20040	COG0440	acetolactate synthase activity
FNR01_RS20045	COG0028	Belongs to the TPP enzyme family
FNR01_RS20050	COG0129	dihydroxy-acid dehydratase activity
FNR01_RS20055	COG1047	Peptidyl-prolyl cis-trans
FNR01_RS20060	COG3681	Belongs to the UPF0597 family
FNR01_RS20090	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNR01_RS20090	COG0551	DNA topoisomerase type I activity
FNR01_RS20100	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNR01_RS20100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNR01_RS20105	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FNR01_RS20110	COG2985	domain, Protein
FNR01_RS20110	COG0569	domain protein
FNR01_RS20130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FNR01_RS20135	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNR01_RS20140	COG0166	Belongs to the GPI family
FNR01_RS20170	COG0789	Transcriptional regulator
FNR01_RS20180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNR01_RS20190	COG2502	aspartate--ammonia ligase
FNR01_RS20195	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FNR01_RS20210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FNR01_RS20220	COG0463	Glycosyl transferase, family 2
FNR01_RS20260	COG0860	N-Acetylmuramoyl-L-alanine amidase
FNR01_RS20290	COG0741	lytic transglycosylase activity
FNR01_RS20290	COG1196	nuclear chromosome segregation
FNR01_RS20290	COG0739	heme binding
FNR01_RS20350	COG2003	Belongs to the UPF0758 family
FNR01_RS20355	COG3250	beta-galactosidase activity
FNR01_RS20370	COG1063	alcohol dehydrogenase
FNR01_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
FNR01_RS20380	COG1012	belongs to the aldehyde dehydrogenase family
FNR01_RS20385	COG4948	Mandelate Racemase Muconate Lactonizing
FNR01_RS20410	COG3250	beta-galactosidase activity
FNR01_RS20425	COG3119	arylsulfatase activity
FNR01_RS20430	COG3292	Two component regulator propeller
FNR01_RS20430	COG2205	protein histidine kinase activity
FNR01_RS20430	COG0745	RESPONSE REGULATOR receiver
FNR01_RS20455	COG0656	L-ascorbic acid biosynthetic process
FNR01_RS20460	COG1629	transport
FNR01_RS20465	COG0702	epimerase
FNR01_RS20475	COG2273	Hydrolase Family 16
FNR01_RS20495	COG3119	arylsulfatase activity
FNR01_RS20530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNR01_RS20540	COG0776	regulation of translation
FNR01_RS20600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNR01_RS20650	COG2433	Pfam Transposase IS66
FNR01_RS20690	COG3177	Filamentation induced by cAMP protein fic
FNR01_RS20740	COG1192	Involved in chromosome partitioning
FNR01_RS20745	COG4974	Belongs to the 'phage' integrase family
FNR01_RS20750	COG4974	Belongs to the 'phage' integrase family
FNR01_RS20780	COG3328	transposase activity
FNR01_RS20800	COG0629	single-stranded DNA binding
FNR01_RS20925	COG0662	Cupin 2, conserved barrel domain protein
FNR01_RS20925	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNR01_RS20940	COG1442	glycosyl transferase family 8
FNR01_RS20940	COG1216	Glycosyl transferase, family 2
FNR01_RS20950	COG0438	transferase activity, transferring glycosyl groups
FNR01_RS20985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNR01_RS20990	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNR01_RS21105	COG4974	Belongs to the 'phage' integrase family
FNR01_RS21130	COG1910	domain protein
FNR01_RS21245	COG1192	Involved in chromosome partitioning
FNR01_RS21260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FNR01_RS21265	COG2205	protein histidine kinase activity
FNR01_RS21265	COG0784	Response regulator, receiver
FNR01_RS21280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNR01_RS21325	COG2003	Belongs to the UPF0758 family
FNR01_RS21370	COG2337	Toxic component of a toxin-antitoxin (TA) module
FNR01_RS21380	COG0776	regulation of translation
FNR01_RS21445	COG4474	Belongs to the UPF0398 family
FNR01_RS21450	COG3385	transposase activity
FNR01_RS21535	COG0629	single-stranded DNA binding