locus-tag	class	description
BVU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVU_RS00010	COG0778	Nitroreductase
BVU_RS00025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BVU_RS00040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVU_RS00045	COG0318	PFAM AMP-dependent synthetase and ligase
BVU_RS00060	COG0359	binds to the 23S rRNA
BVU_RS00065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BVU_RS00070	COG0360	Binds together with S18 to 16S ribosomal RNA
BVU_RS00095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVU_RS00100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVU_RS00160	COG3661	Belongs to the glycosyl hydrolase 67 family
BVU_RS00170	COG3507	Belongs to the glycosyl hydrolase 43 family
BVU_RS00175	COG2382	esterase
BVU_RS00180	COG0745	RESPONSE REGULATOR receiver
BVU_RS00180	COG2205	protein histidine kinase activity
BVU_RS00180	COG3292	Two component regulator propeller
BVU_RS00195	COG0702	epimerase
BVU_RS00200	COG1629	transport
BVU_RS00200	COG4206	TonB-dependent receptor
BVU_RS00220	COG3547	Transposase (IS116 IS110 IS902 family)
BVU_RS00225	COG2211	Major facilitator Superfamily
BVU_RS00240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVU_RS00250	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BVU_RS00255	COG2333	competence protein COMEC
BVU_RS00255	COG0658	competence protein
BVU_RS00260	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVU_RS00280	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVU_RS00290	COG0009	L-threonylcarbamoyladenylate synthase
BVU_RS00295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BVU_RS00330	COG0681	Belongs to the peptidase S26 family
BVU_RS00355	COG0745	RESPONSE REGULATOR receiver
BVU_RS00380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVU_RS00395	COG1280	lysine exporter protein (LysE YggA)
BVU_RS00405	COG2205	protein histidine kinase activity
BVU_RS00405	COG0745	RESPONSE REGULATOR receiver
BVU_RS00405	COG3292	Two component regulator propeller
BVU_RS00410	COG2059	Chromate
BVU_RS00420	COG1649	PFAM Uncharacterised BCR, COG1649
BVU_RS00435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS00450	COG1966	Carbon starvation protein
BVU_RS00475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BVU_RS00480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVU_RS00485	COG0284	orotidine-5'-phosphate decarboxylase activity
BVU_RS00490	COG1078	dGTPase activity
BVU_RS00495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVU_RS00500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BVU_RS00500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVU_RS00515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVU_RS00530	COG5434	Belongs to the glycosyl hydrolase 28 family
BVU_RS00535	COG0673	inositol 2-dehydrogenase activity
BVU_RS00545	COG1629	transport
BVU_RS00560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS00575	COG1629	transport
BVU_RS00575	COG4206	TonB-dependent receptor
BVU_RS00585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS00595	COG4948	Mandelate Racemase Muconate Lactonizing
BVU_RS00640	COG1629	transport
BVU_RS00640	COG4206	TonB-dependent receptor
BVU_RS00665	COG1472	Belongs to the glycosyl hydrolase 3 family
BVU_RS00675	COG4948	Mandelate Racemase Muconate Lactonizing
BVU_RS00680	COG0702	epimerase
BVU_RS00685	COG4771	TonB-dependent receptor
BVU_RS00695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS00700	COG0745	RESPONSE REGULATOR receiver
BVU_RS00700	COG2205	protein histidine kinase activity
BVU_RS00700	COG3292	Two component regulator propeller
BVU_RS00725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVU_RS00725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVU_RS00730	COG0436	Aminotransferase
BVU_RS00740	COG1472	Belongs to the glycosyl hydrolase 3 family
BVU_RS00745	COG0737	Belongs to the 5'-nucleotidase family
BVU_RS00755	COG0335	large ribosomal subunit rRNA binding
BVU_RS00765	COG3292	Two component regulator propeller
BVU_RS00765	COG2205	protein histidine kinase activity
BVU_RS00765	COG0745	RESPONSE REGULATOR receiver
BVU_RS00770	COG3254	rhamnose metabolic process
BVU_RS00775	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS00780	COG3401	FG-GAP repeat protein
BVU_RS00800	COG5433	transposase activity
BVU_RS00825	COG2755	lipolytic protein G-D-S-L family
BVU_RS00830	COG3401	FG-GAP repeat protein
BVU_RS00835	COG3250	beta-galactosidase activity
BVU_RS00845	COG3119	arylsulfatase activity
BVU_RS00855	COG0702	epimerase
BVU_RS00860	COG1629	transport
BVU_RS00870	COG4771	TonB-dependent receptor
BVU_RS00880	COG1629	transport
BVU_RS00905	COG3401	FG-GAP repeat protein
BVU_RS00930	COG3250	beta-galactosidase activity
BVU_RS00935	COG2755	lipolytic protein G-D-S-L family
BVU_RS00970	COG3254	rhamnose metabolic process
BVU_RS00980	COG1136	(ABC) transporter
BVU_RS00985	COG1136	(ABC) transporter
BVU_RS00985	COG0577	efflux transmembrane transporter activity
BVU_RS00990	COG0577	efflux transmembrane transporter activity
BVU_RS00990	COG1136	(ABC) transporter
BVU_RS01015	COG2996	Protein conserved in bacteria
BVU_RS01020	COG1979	alcohol dehydrogenase
BVU_RS01030	COG1136	(ABC) transporter
BVU_RS01035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVU_RS01040	COG0475	glutathione-regulated potassium exporter activity
BVU_RS01040	COG0589	response to stress
BVU_RS01045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVU_RS01050	COG0545	Peptidyl-prolyl cis-trans isomerase
BVU_RS01055	COG0423	glycine-tRNA ligase activity
BVU_RS01080	COG1501	Belongs to the glycosyl hydrolase 31 family
BVU_RS01085	COG1082	Xylose isomerase domain protein TIM barrel
BVU_RS01095	COG0702	epimerase
BVU_RS01100	COG1629	transport
BVU_RS01110	COG2207	Transcriptional regulator
BVU_RS01125	COG0738	Major facilitator superfamily
BVU_RS01130	COG1063	alcohol dehydrogenase
BVU_RS01135	COG2095	MarC family integral membrane protein
BVU_RS01180	COG1696	Membrane protein involved in D-alanine export
BVU_RS01205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS01215	COG1309	transcriptional regulator
BVU_RS01220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVU_RS01235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS01250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVU_RS01285	COG3969	phosphoadenosine phosphosulfate
BVU_RS01290	COG1475	DNA binding
BVU_RS01300	COG0039	L-malate dehydrogenase activity
BVU_RS01315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS01330	COG3015	lipoprotein NlpE involved in copper resistance
BVU_RS01345	COG0489	protein tyrosine kinase activity
BVU_RS01360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVU_RS01365	COG1722	exodeoxyribonuclease VII activity
BVU_RS01370	COG1570	exodeoxyribonuclease VII activity
BVU_RS01380	COG0534	Mate efflux family protein
BVU_RS01430	COG0641	radical SAM
BVU_RS01450	COG0535	radical SAM domain protein
BVU_RS01510	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVU_RS01520	COG1088	dTDP-glucose 4,6-dehydratase activity
BVU_RS01525	COG1629	transport
BVU_RS01535	COG3250	beta-galactosidase activity
BVU_RS01540	COG3408	Glycogen debranching enzyme
BVU_RS01540	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BVU_RS01545	COG0702	epimerase
BVU_RS01550	COG4771	TonB-dependent receptor
BVU_RS01565	COG0488	(ABC) transporter
BVU_RS01570	COG2985	domain, Protein
BVU_RS01570	COG0569	domain protein
BVU_RS01575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVU_RS01580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVU_RS01580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVU_RS01600	COG1629	transport
BVU_RS01600	COG4206	TonB-dependent receptor
BVU_RS01605	COG2205	protein histidine kinase activity
BVU_RS01610	COG0668	transmembrane transport
BVU_RS01635	COG0681	Belongs to the peptidase S26 family
BVU_RS01655	COG2086	electron transfer activity
BVU_RS01660	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVU_RS01690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVU_RS01700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BVU_RS01715	COG1228	amidohydrolase
BVU_RS01720	COG3404	Formiminotransferase-cyclodeaminase
BVU_RS01725	COG2986	histidine ammonia-lyase
BVU_RS01730	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BVU_RS01735	COG0673	inositol 2-dehydrogenase activity
BVU_RS01740	COG0288	reversible hydration of carbon dioxide
BVU_RS01760	COG0459	protein refolding
BVU_RS01765	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVU_RS01775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVU_RS01785	COG1160	GTP binding
BVU_RS01790	COG0124	histidyl-tRNA synthetase
BVU_RS01795	COG1879	ABC-type sugar transport system periplasmic component
BVU_RS01810	COG1879	ABC-type sugar transport system periplasmic component
BVU_RS01830	COG3958	Transketolase
BVU_RS01835	COG3959	Transketolase, thiamine diphosphate binding domain
BVU_RS01840	COG1349	DNA-binding transcription factor activity
BVU_RS01845	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVU_RS01845	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVU_RS01855	COG3292	Two component regulator propeller
BVU_RS01855	COG2205	protein histidine kinase activity
BVU_RS01855	COG0745	RESPONSE REGULATOR receiver
BVU_RS01865	COG1629	transport
BVU_RS01920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVU_RS01930	COG0534	Mate efflux family protein
BVU_RS01935	COG0784	Response regulator, receiver
BVU_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVU_RS01935	COG2198	Histidine kinase
BVU_RS01935	COG2205	protein histidine kinase activity
BVU_RS01940	COG2204	response regulator
BVU_RS01950	COG0564	pseudouridine synthase activity
BVU_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS01980	COG1629	transport
BVU_RS01985	COG0702	epimerase
BVU_RS01990	COG3250	beta-galactosidase activity
BVU_RS02000	COG3250	beta-galactosidase activity
BVU_RS02030	COG0513	Belongs to the DEAD box helicase family
BVU_RS02060	COG0482	sulfurtransferase activity
BVU_RS02065	COG2197	response regulator
BVU_RS02095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVU_RS02110	COG3022	response to hydroperoxide
BVU_RS02115	COG2885	chlorophyll binding
BVU_RS02125	COG2895	sulfate adenylyltransferase (ATP) activity
BVU_RS02130	COG0175	sulfate reduction
BVU_RS02135	COG0529	Catalyzes the synthesis of activated sulfate
BVU_RS02140	COG0471	metal ion transport
BVU_RS02140	COG3273	potassium ion transport
BVU_RS02155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVU_RS02180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVU_RS02185	COG0516	GMP reductase activity
BVU_RS02185	COG0517	IMP dehydrogenase activity
BVU_RS02245	COG0582	viral genome integration into host DNA
BVU_RS02270	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVU_RS02275	COG0740	serine-type endopeptidase activity
BVU_RS02280	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVU_RS02285	COG0724	RNA recognition motif
BVU_RS02295	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVU_RS02300	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVU_RS02305	COG1160	GTP binding
BVU_RS02310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVU_RS02315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVU_RS02370	COG0039	L-malate dehydrogenase activity
BVU_RS02375	COG0358	DNA primase activity
BVU_RS02380	COG0302	gtp cyclohydrolase
BVU_RS02390	COG0149	triose-phosphate isomerase activity
BVU_RS02405	COG0739	heme binding
BVU_RS02410	COG0105	UTP biosynthetic process
BVU_RS02415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVU_RS02420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVU_RS02435	COG0848	biopolymer transport protein
BVU_RS02440	COG0811	peptide transport
BVU_RS02445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVU_RS02450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVU_RS02495	COG0420	3'-5' exonuclease activity
BVU_RS02505	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BVU_RS02515	COG1501	Belongs to the glycosyl hydrolase 31 family
BVU_RS02520	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS02525	COG1629	transport
BVU_RS02525	COG4206	TonB-dependent receptor
BVU_RS02530	COG4977	sequence-specific DNA binding
BVU_RS02555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS02560	COG4206	TonB-dependent receptor
BVU_RS02560	COG1629	transport
BVU_RS02580	COG4771	TonB-dependent receptor
BVU_RS02585	COG0702	epimerase
BVU_RS02600	COG3507	Belongs to the glycosyl hydrolase 43 family
BVU_RS02610	COG4771	TonB-dependent receptor
BVU_RS02615	COG3292	Two component regulator propeller
BVU_RS02615	COG2205	protein histidine kinase activity
BVU_RS02615	COG0745	RESPONSE REGULATOR receiver
BVU_RS02635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BVU_RS02640	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVU_RS02645	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BVU_RS02660	COG1346	cytolysis
BVU_RS02670	COG0280	phosphate acetyltransferase
BVU_RS02675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVU_RS02680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVU_RS02685	COG2151	metal-sulfur cluster biosynthetic enzyme
BVU_RS02690	COG2003	Belongs to the UPF0758 family
BVU_RS02695	COG0463	Glycosyl transferase, family 2
BVU_RS02695	COG1216	Glycosyl transferase, family 2
BVU_RS02700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVU_RS02705	COG0641	radical SAM
BVU_RS02735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS02740	COG3119	arylsulfatase activity
BVU_RS02745	COG0702	epimerase
BVU_RS02750	COG4771	TonB-dependent receptor
BVU_RS02755	COG2755	lipolytic protein G-D-S-L family
BVU_RS02755	COG0657	acetylesterase activity
BVU_RS02760	COG0745	RESPONSE REGULATOR receiver
BVU_RS02760	COG2205	protein histidine kinase activity
BVU_RS02760	COG3292	Two component regulator propeller
BVU_RS02780	COG0564	pseudouridine synthase activity
BVU_RS02785	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVU_RS02800	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BVU_RS02805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVU_RS02810	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BVU_RS02815	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVU_RS02820	COG0561	phosphatase activity
BVU_RS02850	COG1629	transport
BVU_RS02850	COG4206	TonB-dependent receptor
BVU_RS02860	COG4206	TonB-dependent receptor
BVU_RS02860	COG1629	transport
BVU_RS02885	COG1629	transport
BVU_RS02885	COG4206	TonB-dependent receptor
BVU_RS02900	COG1629	transport
BVU_RS02900	COG4206	TonB-dependent receptor
BVU_RS02915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVU_RS02920	COG1917	Cupin 2, conserved barrel domain protein
BVU_RS02920	COG1396	sequence-specific DNA binding
BVU_RS02930	COG0348	domain, Protein
BVU_RS02935	COG0667	Aldo Keto reductase
BVU_RS02945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVU_RS02950	COG1368	sulfuric ester hydrolase activity
BVU_RS02955	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BVU_RS02965	COG0702	epimerase
BVU_RS02970	COG1629	transport
BVU_RS02970	COG4206	TonB-dependent receptor
BVU_RS02990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BVU_RS02995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVU_RS03000	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BVU_RS03005	COG0137	argininosuccinate synthase activity
BVU_RS03015	COG1438	arginine binding
BVU_RS03020	COG1070	Carbohydrate kinase
BVU_RS03025	COG4806	L-rhamnose isomerase
BVU_RS03035	COG0235	Class ii aldolase
BVU_RS03050	COG0702	epimerase
BVU_RS03055	COG1629	transport
BVU_RS03055	COG4206	TonB-dependent receptor
BVU_RS03060	COG0745	RESPONSE REGULATOR receiver
BVU_RS03060	COG2205	protein histidine kinase activity
BVU_RS03060	COG3292	Two component regulator propeller
BVU_RS03070	COG0741	lytic transglycosylase activity
BVU_RS03070	COG1388	LysM domain
BVU_RS03075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVU_RS03080	COG3250	beta-galactosidase activity
BVU_RS03100	COG0673	inositol 2-dehydrogenase activity
BVU_RS03105	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BVU_RS03140	COG1629	transport
BVU_RS03140	COG4206	TonB-dependent receptor
BVU_RS03145	COG1082	Xylose isomerase domain protein TIM barrel
BVU_RS03160	COG4771	TonB-dependent receptor
BVU_RS03170	COG3537	Alpha-1,2-mannosidase
BVU_RS03215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVU_RS03220	COG0542	response to heat
BVU_RS03225	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVU_RS03235	COG0534	Mate efflux family protein
BVU_RS03245	COG2197	response regulator
BVU_RS03250	COG3345	alpha-galactosidase
BVU_RS03440	COG1192	Involved in chromosome partitioning
BVU_RS03475	COG0784	Response regulator, receiver
BVU_RS03475	COG2205	protein histidine kinase activity
BVU_RS03495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVU_RS03530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVU_RS03545	COG1086	Polysaccharide biosynthesis protein
BVU_RS03570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVU_RS03615	COG0551	DNA topoisomerase type I activity
BVU_RS03615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVU_RS03720	COG0561	phosphatase activity
BVU_RS03725	COG4771	TonB-dependent receptor
BVU_RS03760	COG4771	TonB-dependent receptor
BVU_RS03765	COG1472	Belongs to the glycosyl hydrolase 3 family
BVU_RS03780	COG0702	epimerase
BVU_RS03785	COG1629	transport
BVU_RS03795	COG3292	Two component regulator propeller
BVU_RS03795	COG2205	protein histidine kinase activity
BVU_RS03795	COG3292	Two component regulator propeller
BVU_RS03795	COG0745	RESPONSE REGULATOR receiver
BVU_RS03795	COG0745	RESPONSE REGULATOR receiver
BVU_RS03795	COG2205	protein histidine kinase activity
BVU_RS03805	COG0457	Tetratricopeptide repeat
BVU_RS03810	COG2814	Major facilitator Superfamily
BVU_RS03830	COG3537	Alpha-1,2-mannosidase
BVU_RS03835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVU_RS03835	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BVU_RS03845	COG1373	ATPase (AAA superfamily
BVU_RS03860	COG1629	transport
BVU_RS03860	COG4206	TonB-dependent receptor
BVU_RS03900	COG2873	o-acetylhomoserine
BVU_RS03915	COG1595	DNA-templated transcription, initiation
BVU_RS03955	COG0203	ribosomal protein L17
BVU_RS03960	COG0202	RNA polymerase activity
BVU_RS03965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVU_RS03970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVU_RS03975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVU_RS03980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BVU_RS03995	COG0200	Binds to the 23S rRNA
BVU_RS04000	COG1841	ribosomal large subunit assembly
BVU_RS04005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVU_RS04010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVU_RS04015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVU_RS04020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BVU_RS04025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BVU_RS04030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVU_RS04035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVU_RS04040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVU_RS04045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BVU_RS04050	COG0255	Belongs to the universal ribosomal protein uL29 family
BVU_RS04055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVU_RS04060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVU_RS04065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVU_RS04070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVU_RS04075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVU_RS04080	COG0089	rRNA binding
BVU_RS04085	COG0088	Forms part of the polypeptide exit tunnel
BVU_RS04090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVU_RS04095	COG0051	transcription antitermination factor activity, RNA binding
BVU_RS04100	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVU_RS04105	COG0049	tRNA binding
BVU_RS04110	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVU_RS04125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVU_RS04130	COG0085	RNA polymerase activity
BVU_RS04135	COG0222	ribosome binding
BVU_RS04140	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVU_RS04145	COG0081	regulation of translation
BVU_RS04150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BVU_RS04165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVU_RS04195	COG4974	Belongs to the 'phage' integrase family
BVU_RS04200	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVU_RS04210	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BVU_RS04225	COG0745	RESPONSE REGULATOR receiver
BVU_RS04230	COG5002	protein histidine kinase activity
BVU_RS04240	COG0793	Belongs to the peptidase S41A family
BVU_RS04245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVU_RS04260	COG3292	Two component regulator propeller
BVU_RS04260	COG2205	protein histidine kinase activity
BVU_RS04260	COG0745	RESPONSE REGULATOR receiver
BVU_RS04270	COG4771	TonB-dependent receptor
BVU_RS04275	COG0702	epimerase
BVU_RS04295	COG3634	alkyl hydroperoxide reductase activity
BVU_RS04320	COG4206	TonB-dependent receptor
BVU_RS04325	COG0519	Catalyzes the synthesis of GMP from XMP
BVU_RS04350	COG0667	Aldo Keto reductase
BVU_RS04355	COG0165	Argininosuccinate lyase
BVU_RS04365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BVU_RS04370	COG1040	competence protein
BVU_RS04380	COG2890	protein-(glutamine-N5) methyltransferase activity
BVU_RS04385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVU_RS04385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVU_RS04395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVU_RS04415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVU_RS04420	COG0351	phosphomethylpyrimidine kinase
BVU_RS04430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVU_RS04445	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BVU_RS04450	COG4974	Belongs to the 'phage' integrase family
BVU_RS04465	COG0606	chelatase, subunit chli
BVU_RS04470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVU_RS04470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVU_RS04490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVU_RS04500	COG3475	LICD family
BVU_RS04515	COG0438	transferase activity, transferring glycosyl groups
BVU_RS04530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVU_RS04535	COG1854	S-ribosylhomocysteine lyase activity
BVU_RS04540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVU_RS04775	COG0739	heme binding
BVU_RS04775	COG0741	lytic transglycosylase activity
BVU_RS04775	COG1196	nuclear chromosome segregation
BVU_RS04805	COG1629	transport
BVU_RS04825	COG0673	inositol 2-dehydrogenase activity
BVU_RS04840	COG1192	Involved in chromosome partitioning
BVU_RS04850	COG3392	D12 class N6 adenine-specific DNA methyltransferase
BVU_RS04870	COG4206	TonB-dependent receptor
BVU_RS04870	COG1629	transport
BVU_RS04875	COG0702	epimerase
BVU_RS04935	COG3292	Two component regulator propeller
BVU_RS04935	COG2205	protein histidine kinase activity
BVU_RS04935	COG0745	RESPONSE REGULATOR receiver
BVU_RS04940	COG1217	gtp-binding protein TYPA
BVU_RS04950	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BVU_RS04955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVU_RS04960	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVU_RS04965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVU_RS04965	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVU_RS04980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS04985	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BVU_RS04990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVU_RS04995	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVU_RS05000	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVU_RS05000	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVU_RS05015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS05025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVU_RS05030	COG0339	signal peptide processing
BVU_RS05055	COG3250	beta-galactosidase activity
BVU_RS05065	COG0482	sulfurtransferase activity
BVU_RS05070	COG3119	arylsulfatase activity
BVU_RS05080	COG3507	Belongs to the glycosyl hydrolase 43 family
BVU_RS05085	COG0745	RESPONSE REGULATOR receiver
BVU_RS05085	COG3292	Two component regulator propeller
BVU_RS05085	COG2205	protein histidine kinase activity
BVU_RS05090	COG1082	Xylose isomerase domain protein TIM barrel
BVU_RS05095	COG4206	TonB-dependent receptor
BVU_RS05095	COG1629	transport
BVU_RS05115	COG0215	cysteine-tRNA ligase activity
BVU_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS05135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVU_RS05160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVU_RS05170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVU_RS05200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVU_RS05245	COG0784	Response regulator, receiver
BVU_RS05245	COG2205	protein histidine kinase activity
BVU_RS05270	COG0205	6-phosphofructokinase activity
BVU_RS05280	COG4206	TonB-dependent receptor
BVU_RS05280	COG1629	transport
BVU_RS05290	COG3119	arylsulfatase activity
BVU_RS05305	COG3119	arylsulfatase activity
BVU_RS05310	COG0571	ribonuclease III activity
BVU_RS05315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVU_RS05320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVU_RS05325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVU_RS05335	COG4206	TonB-dependent receptor
BVU_RS05335	COG1629	transport
BVU_RS05365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVU_RS05380	COG0562	UDP-galactopyranose mutase
BVU_RS05410	COG0438	transferase activity, transferring glycosyl groups
BVU_RS05425	COG1132	(ABC) transporter
BVU_RS05435	COG1215	transferase activity, transferring glycosyl groups
BVU_RS05445	COG0463	Glycosyl transferase, family 2
BVU_RS05455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVU_RS05465	COG3341	Caulimovirus viroplasmin
BVU_RS05465	COG0328	RNA-DNA hybrid ribonuclease activity
BVU_RS05470	COG0018	arginyl-trna synthetase
BVU_RS05475	COG1629	transport
BVU_RS05485	COG0826	peptidase U32
BVU_RS05490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVU_RS05510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVU_RS05515	COG0557	exoribonuclease II activity
BVU_RS05520	COG1045	serine acetyltransferase
BVU_RS05530	COG0116	Belongs to the methyltransferase superfamily
BVU_RS05535	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS05535	COG1506	peptidase
BVU_RS05555	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BVU_RS05555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVU_RS05585	COG0726	polysaccharide deacetylase
BVU_RS05590	COG4677	pectinesterase activity
BVU_RS05595	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS05600	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BVU_RS05630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVU_RS05655	COG0702	epimerase
BVU_RS05660	COG1629	transport
BVU_RS05660	COG4206	TonB-dependent receptor
BVU_RS05680	COG4948	Mandelate Racemase Muconate Lactonizing
BVU_RS05700	COG1629	transport
BVU_RS05700	COG4206	TonB-dependent receptor
BVU_RS05725	COG1629	transport
BVU_RS05725	COG4206	TonB-dependent receptor
BVU_RS05730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS05740	COG0745	RESPONSE REGULATOR receiver
BVU_RS05740	COG3292	Two component regulator propeller
BVU_RS05740	COG2205	protein histidine kinase activity
BVU_RS05745	COG1592	Rubrerythrin
BVU_RS05755	COG0659	secondary active sulfate transmembrane transporter activity
BVU_RS05765	COG0731	radical SAM domain protein
BVU_RS05765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVU_RS05790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVU_RS05795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVU_RS05805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVU_RS05810	COG0495	leucyl-tRNA aminoacylation
BVU_RS05815	COG0745	RESPONSE REGULATOR receiver
BVU_RS05815	COG2205	protein histidine kinase activity
BVU_RS05815	COG3292	Two component regulator propeller
BVU_RS05815	COG0745	RESPONSE REGULATOR receiver
BVU_RS05815	COG3292	Two component regulator propeller
BVU_RS05815	COG2205	protein histidine kinase activity
BVU_RS05820	COG3250	beta-galactosidase activity
BVU_RS05825	COG1629	transport
BVU_RS05830	COG0702	epimerase
BVU_RS05835	COG4946	Tricorn protease homolog
BVU_RS05835	COG0793	Belongs to the peptidase S41A family
BVU_RS05840	COG1595	DNA-templated transcription, initiation
BVU_RS05850	COG4206	TonB-dependent receptor
BVU_RS05850	COG1629	transport
BVU_RS05860	COG3119	arylsulfatase activity
BVU_RS05865	COG3119	arylsulfatase activity
BVU_RS05870	COG0488	(ABC) transporter
BVU_RS05875	COG1472	Belongs to the glycosyl hydrolase 3 family
BVU_RS05880	COG0427	acetyl-CoA hydrolase
BVU_RS05890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVU_RS05895	COG0545	Peptidyl-prolyl cis-trans isomerase
BVU_RS05900	COG1983	PspC domain protein
BVU_RS05910	COG2177	Part of the ABC transporter FtsEX involved in
BVU_RS05920	COG1968	undecaprenyl-diphosphatase activity
BVU_RS05925	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVU_RS05930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVU_RS05935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVU_RS05980	COG2814	Major facilitator Superfamily
BVU_RS05985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVU_RS06005	COG0594	ribonuclease P activity
BVU_RS06010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVU_RS06020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVU_RS06025	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS06025	COG4946	Tricorn protease homolog
BVU_RS06025	COG1506	peptidase
BVU_RS06040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVU_RS06080	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVU_RS06090	COG0012	GTP binding
BVU_RS06100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVU_RS06100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVU_RS06105	COG0142	geranyltranstransferase activity
BVU_RS06115	COG1694	Mazg nucleotide pyrophosphohydrolase
BVU_RS06120	COG1490	D-aminoacyl-tRNA deacylase activity
BVU_RS06125	COG0322	excinuclease ABC activity
BVU_RS06135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVU_RS06140	COG0445	tRNA wobble uridine modification
BVU_RS06145	COG2268	Band 7 protein
BVU_RS06155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BVU_RS06160	COG0700	Nucleoside recognition
BVU_RS06250	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVU_RS06255	COG3409	Peptidoglycan-binding domain 1 protein
BVU_RS06255	COG0793	Belongs to the peptidase S41A family
BVU_RS06270	COG1053	succinate dehydrogenase
BVU_RS06305	COG0758	DNA mediated transformation
BVU_RS06305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVU_RS06325	COG1454	alcohol dehydrogenase
BVU_RS06335	COG4771	TonB-dependent receptor
BVU_RS06355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVU_RS06360	COG0681	Belongs to the peptidase S26 family
BVU_RS06365	COG0681	Belongs to the peptidase S26 family
BVU_RS06375	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS06380	COG1312	Catalyzes the dehydration of D-mannonate
BVU_RS06390	COG4771	TonB-dependent receptor
BVU_RS06400	COG3119	arylsulfatase activity
BVU_RS06405	COG2205	protein histidine kinase activity
BVU_RS06405	COG0745	RESPONSE REGULATOR receiver
BVU_RS06405	COG2205	protein histidine kinase activity
BVU_RS06405	COG0745	RESPONSE REGULATOR receiver
BVU_RS06405	COG3292	Two component regulator propeller
BVU_RS06405	COG3292	Two component regulator propeller
BVU_RS06415	COG0612	Peptidase, M16
BVU_RS06425	COG0517	IMP dehydrogenase activity
BVU_RS06425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BVU_RS06440	COG0308	aminopeptidase N
BVU_RS06445	COG0482	sulfurtransferase activity
BVU_RS06510	COG4974	Belongs to the 'phage' integrase family
BVU_RS06515	COG2255	four-way junction helicase activity
BVU_RS06530	COG3591	Belongs to the peptidase S1B family
BVU_RS06540	COG3655	Transcriptional regulator
BVU_RS06580	COG0196	riboflavin kinase activity
BVU_RS06585	COG1011	Hydrolase
BVU_RS06590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVU_RS06640	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BVU_RS06665	COG2166	iron-sulfur cluster assembly
BVU_RS06675	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVU_RS06680	COG0280	phosphate acetyltransferase
BVU_RS06685	COG3426	butyrate kinase activity
BVU_RS06730	COG1522	sequence-specific DNA binding
BVU_RS06740	COG1253	flavin adenine dinucleotide binding
BVU_RS06745	COG2816	NAD+ diphosphatase activity
BVU_RS06765	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVU_RS06770	COG1166	arginine decarboxylase activity
BVU_RS06775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVU_RS06780	COG1595	DNA-templated transcription, initiation
BVU_RS06800	COG3458	cephalosporin-C deacetylase activity
BVU_RS06840	COG2814	Major facilitator Superfamily
BVU_RS06850	COG0779	Required for maturation of 30S ribosomal subunits
BVU_RS06855	COG0195	Participates in both transcription termination and antitermination
BVU_RS06860	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVU_RS06870	COG0719	Fe-S assembly protein
BVU_RS06875	COG0396	ATPase activity
BVU_RS06880	COG0719	Fe-S assembly protein
BVU_RS06885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVU_RS06900	COG0456	acetyltransferase
BVU_RS06905	COG3408	Glycogen debranching enzyme
BVU_RS06905	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BVU_RS06910	COG3250	beta-galactosidase activity
BVU_RS06915	COG2431	L-lysine efflux transmembrane transporter activity
BVU_RS06925	COG0702	epimerase
BVU_RS06930	COG1629	transport
BVU_RS06930	COG4206	TonB-dependent receptor
BVU_RS06940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVU_RS06945	COG0738	Major facilitator superfamily
BVU_RS06950	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
BVU_RS06960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BVU_RS06980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS06985	COG4206	TonB-dependent receptor
BVU_RS06985	COG1629	transport
BVU_RS06990	COG1082	Xylose isomerase domain protein TIM barrel
BVU_RS06995	COG0366	Alpha amylase catalytic
BVU_RS07020	COG1640	4-alpha-glucanotransferase
BVU_RS07025	COG0187	DNA topoisomerase II activity
BVU_RS07030	COG0268	Binds directly to 16S ribosomal RNA
BVU_RS07040	COG1381	Involved in DNA repair and RecF pathway recombination
BVU_RS07050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVU_RS07055	COG0849	cell division
BVU_RS07065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVU_RS07070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVU_RS07075	COG0772	Belongs to the SEDS family
BVU_RS07080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVU_RS07085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVU_RS07090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVU_RS07095	COG0768	penicillin binding
BVU_RS07105	COG0275	rRNA processing
BVU_RS07110	COG2001	Belongs to the MraZ family
BVU_RS07130	COG0756	dUTP diphosphatase activity
BVU_RS07135	COG3063	Type IV pilus biogenesis stability protein PilW
BVU_RS07150	COG0724	RNA recognition motif
BVU_RS07155	COG2066	Belongs to the glutaminase family
BVU_RS07160	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BVU_RS07165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BVU_RS07170	COG0509	glycine decarboxylation via glycine cleavage system
BVU_RS07190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVU_RS07200	COG0572	uridine kinase
BVU_RS07205	COG1283	sodium-dependent phosphate transmembrane transporter activity
BVU_RS07220	COG0545	Peptidyl-prolyl cis-trans isomerase
BVU_RS07225	COG0545	Peptidyl-prolyl cis-trans isomerase
BVU_RS07230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVU_RS07235	COG1773	rubredoxin
BVU_RS07245	COG1185	polyribonucleotide nucleotidyltransferase activity
BVU_RS07255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVU_RS07265	COG0662	Cupin 2, conserved barrel domain protein
BVU_RS07265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BVU_RS07290	COG0358	DNA primase activity
BVU_RS07335	COG4804	nuclease activity
BVU_RS07340	COG4974	Belongs to the 'phage' integrase family
BVU_RS07390	COG3153	acetyltransferase
BVU_RS07400	COG3189	MarR family transcriptional regulator
BVU_RS07405	COG0439	Biotin carboxylase
BVU_RS07415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVU_RS07430	COG2096	Adenosyltransferase
BVU_RS07445	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVU_RS07450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BVU_RS07455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVU_RS07465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVU_RS07470	COG1519	Transferase
BVU_RS07510	COG1022	Amp-dependent synthetase and ligase
BVU_RS07525	COG2954	triphosphatase activity
BVU_RS07545	COG0733	neurotransmitter:sodium symporter activity
BVU_RS07560	COG1785	Belongs to the alkaline phosphatase family
BVU_RS07600	COG0110	maltose O-acetyltransferase activity
BVU_RS07605	COG0546	phosphoglycolate phosphatase activity
BVU_RS07620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVU_RS07730	COG0551	DNA topoisomerase type I activity
BVU_RS07730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVU_RS07790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BVU_RS07815	COG1086	Polysaccharide biosynthesis protein
BVU_RS07830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVU_RS07865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVU_RS07880	COG0784	Response regulator, receiver
BVU_RS07880	COG2205	protein histidine kinase activity
BVU_RS07920	COG1192	Involved in chromosome partitioning
BVU_RS08105	COG3385	transposase activity
BVU_RS08140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVU_RS08145	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVU_RS08150	COG1663	tetraacyldisaccharide 4'-kinase activity
BVU_RS08155	COG0616	signal peptide processing
BVU_RS08170	COG1929	Belongs to the glycerate kinase type-1 family
BVU_RS08210	COG0811	peptide transport
BVU_RS08240	COG1131	(ABC) transporter
BVU_RS08260	COG0534	Mate efflux family protein
BVU_RS08270	COG1187	pseudouridine synthase activity
BVU_RS08275	COG0017	Asparaginyl-tRNA synthetase
BVU_RS08295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVU_RS08300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVU_RS08305	COG0052	Belongs to the universal ribosomal protein uS2 family
BVU_RS08310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVU_RS08320	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BVU_RS08325	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVU_RS08330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVU_RS08335	COG1575	Belongs to the MenA family. Type 1 subfamily
BVU_RS08340	COG1408	metallophosphoesterase
BVU_RS08350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVU_RS08360	COG0194	GDP metabolic process
BVU_RS08380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVU_RS08385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVU_RS08390	COG0739	heme binding
BVU_RS08395	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVU_RS08400	COG0750	zinc metalloprotease
BVU_RS08415	COG1272	protein, Hemolysin III
BVU_RS08420	COG0617	tRNA 3'-terminal CCA addition
BVU_RS08430	COG0632	four-way junction helicase activity
BVU_RS08435	COG0673	inositol 2-dehydrogenase activity
BVU_RS08440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVU_RS08455	COG1621	beta-fructofuranosidase activity
BVU_RS08465	COG1105	Belongs to the carbohydrate kinase PfkB family
BVU_RS08470	COG2205	protein histidine kinase activity
BVU_RS08470	COG0745	RESPONSE REGULATOR receiver
BVU_RS08470	COG3292	Two component regulator propeller
BVU_RS08480	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVU_RS08490	COG0254	rRNA binding
BVU_RS08495	COG0191	fructose-bisphosphate aldolase activity
BVU_RS08540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVU_RS08540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVU_RS08545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BVU_RS08550	COG0563	adenylate kinase activity
BVU_RS08555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVU_RS08560	COG1496	oxidoreductase activity
BVU_RS08605	COG0138	bifunctional purine biosynthesis protein purh
BVU_RS08655	COG1482	cell wall glycoprotein biosynthetic process
BVU_RS08660	COG2706	6-phosphogluconolactonase activity
BVU_RS08690	COG4771	TonB-dependent receptor
BVU_RS08695	COG0702	epimerase
BVU_RS08700	COG0584	glycerophosphoryl diester phosphodiesterase
BVU_RS08765	COG1216	Glycosyl transferase, family 2
BVU_RS08775	COG0438	transferase activity, transferring glycosyl groups
BVU_RS08780	COG0438	transferase activity, transferring glycosyl groups
BVU_RS08795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVU_RS08875	COG0523	cobalamin synthesis protein
BVU_RS08890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS08895	COG1007	ATP synthesis coupled electron transport
BVU_RS08900	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVU_RS08905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVU_RS08915	COG0839	Belongs to the complex I subunit 6 family
BVU_RS08920	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVU_RS08925	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BVU_RS08930	COG0649	NAD binding
BVU_RS08935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVU_RS08940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVU_RS08950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVU_RS08955	COG0569	domain protein
BVU_RS08960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVU_RS08970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVU_RS08985	COG3250	beta-galactosidase activity
BVU_RS09000	COG3119	arylsulfatase activity
BVU_RS09005	COG0702	epimerase
BVU_RS09010	COG1629	transport
BVU_RS09010	COG4206	TonB-dependent receptor
BVU_RS09045	COG4206	TonB-dependent receptor
BVU_RS09045	COG1629	transport
BVU_RS09050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS09065	COG3250	beta-galactosidase activity
BVU_RS09075	COG2205	protein histidine kinase activity
BVU_RS09075	COG0745	RESPONSE REGULATOR receiver
BVU_RS09075	COG3292	Two component regulator propeller
BVU_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
BVU_RS09105	COG2271	Major facilitator Superfamily
BVU_RS09110	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BVU_RS09115	COG3775	system Galactitol-specific IIC component
BVU_RS09120	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS09130	COG1629	transport
BVU_RS09130	COG4206	TonB-dependent receptor
BVU_RS09165	COG4771	TonB-dependent receptor
BVU_RS09175	COG3250	beta-galactosidase activity
BVU_RS09195	COG1917	Cupin 2, conserved barrel domain protein
BVU_RS09210	COG2755	lipolytic protein G-D-S-L family
BVU_RS09215	COG0745	RESPONSE REGULATOR receiver
BVU_RS09215	COG3292	Two component regulator propeller
BVU_RS09215	COG2205	protein histidine kinase activity
BVU_RS09225	COG1506	peptidase
BVU_RS09225	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS09240	COG0138	bifunctional purine biosynthesis protein purh
BVU_RS09260	COG0768	penicillin binding
BVU_RS09265	COG0772	Belongs to the SEDS family
BVU_RS09275	COG1774	PSP1 C-terminal conserved region
BVU_RS09280	COG0470	DNA polymerase III
BVU_RS09285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVU_RS09300	COG0628	permease
BVU_RS09305	COG1435	thymidine kinase activity
BVU_RS09310	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BVU_RS09330	COG4206	TonB-dependent receptor
BVU_RS09330	COG1629	transport
BVU_RS09335	COG4974	Belongs to the 'phage' integrase family
BVU_RS09340	COG4206	TonB-dependent receptor
BVU_RS09340	COG1629	transport
BVU_RS09360	COG4206	TonB-dependent receptor
BVU_RS09360	COG1629	transport
BVU_RS09375	COG4771	TonB-dependent receptor
BVU_RS09385	COG4771	TonB-dependent receptor
BVU_RS09395	COG4771	TonB-dependent receptor
BVU_RS09405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVU_RS09420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BVU_RS09420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BVU_RS09430	COG0531	amino acid
BVU_RS09440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVU_RS09445	COG1566	PFAM secretion protein HlyD family protein
BVU_RS09455	COG1162	GTPase activity
BVU_RS09460	COG0233	cytoplasmic translational termination
BVU_RS09485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS09490	COG0528	UMP kinase activity
BVU_RS09495	COG0534	Mate efflux family protein
BVU_RS09510	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BVU_RS09510	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BVU_RS09520	COG0792	nuclease activity
BVU_RS09540	COG1183	phosphatidylcholine synthase activity
BVU_RS09545	COG0688	phosphatidylethanolamine metabolic process
BVU_RS09575	COG0802	atpase or kinase
BVU_RS09580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVU_RS09595	COG1830	Aldolase
BVU_RS09600	COG0588	phosphoglycerate mutase activity
BVU_RS09625	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BVU_RS09640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVU_RS09645	COG0742	ribosomal rna small subunit methyltransferase
BVU_RS09665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVU_RS09670	COG0739	heme binding
BVU_RS09685	COG1388	LysM domain
BVU_RS09685	COG1705	Flagellar rod assembly protein muramidase FlgJ
BVU_RS09695	COG1475	DNA binding
BVU_RS09700	COG1192	Involved in chromosome partitioning
BVU_RS09705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVU_RS09710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVU_RS09725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVU_RS09740	COG1196	nuclear chromosome segregation
BVU_RS09745	COG2239	Acts as a magnesium transporter
BVU_RS09750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVU_RS09760	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVU_RS09765	COG0590	tRNA wobble adenosine to inosine editing
BVU_RS09775	COG1396	sequence-specific DNA binding
BVU_RS09785	COG2373	Large extracellular alpha-helical protein
BVU_RS09805	COG0205	6-phosphofructokinase activity
BVU_RS09810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVU_RS09815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVU_RS09830	COG0084	hydrolase, TatD family'
BVU_RS09840	COG0811	peptide transport
BVU_RS09875	COG1522	sequence-specific DNA binding
BVU_RS09885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVU_RS09895	COG1595	DNA-templated transcription, initiation
BVU_RS09925	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BVU_RS09935	COG0538	isocitrate dehydrogenase activity
BVU_RS09940	COG0372	Belongs to the citrate synthase family
BVU_RS09990	COG0205	6-phosphofructokinase activity
BVU_RS09995	COG0546	phosphoglycolate phosphatase activity
BVU_RS10010	COG0511	ligase activity, forming carbon-carbon bonds
BVU_RS10015	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BVU_RS10020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS10030	COG0561	phosphatase activity
BVU_RS10035	COG4771	TonB-dependent receptor
BVU_RS10065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BVU_RS10085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVU_RS10090	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS10090	COG1506	peptidase
BVU_RS10095	COG1242	4 iron, 4 sulfur cluster binding
BVU_RS10100	COG0426	domain, Protein
BVU_RS10105	COG0668	transmembrane transport
BVU_RS10110	COG0009	L-threonylcarbamoyladenylate synthase
BVU_RS10115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVU_RS10160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVU_RS10165	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVU_RS10170	COG0066	3-isopropylmalate dehydratase activity
BVU_RS10180	COG0473	3-isopropylmalate dehydrogenase activity
BVU_RS10190	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVU_RS10205	COG0514	ATP-dependent DNA helicase (RecQ)
BVU_RS10225	COG0735	belongs to the Fur family
BVU_RS10230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVU_RS10240	COG4771	TonB-dependent receptor
BVU_RS10275	COG4771	TonB-dependent receptor
BVU_RS10290	COG0488	(ABC) transporter
BVU_RS10295	COG3590	peptidase
BVU_RS10305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS10330	COG0673	inositol 2-dehydrogenase activity
BVU_RS10335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BVU_RS10340	COG0826	peptidase U32
BVU_RS10350	COG4771	TonB-dependent receptor
BVU_RS10360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BVU_RS10370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BVU_RS10375	COG0527	aspartate kinase activity
BVU_RS10375	COG0460	homoserine dehydrogenase
BVU_RS10380	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BVU_RS10385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BVU_RS10395	COG1120	ATPase activity
BVU_RS10400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVU_RS10420	COG1073	alpha beta
BVU_RS10435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BVU_RS10440	COG0436	Aminotransferase
BVU_RS10450	COG1733	regulation of RNA biosynthetic process
BVU_RS10460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVU_RS10465	COG0628	permease
BVU_RS10475	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS10480	COG0514	ATP-dependent DNA helicase (RecQ)
BVU_RS10485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BVU_RS10485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVU_RS10495	COG0006	proline dipeptidase activity
BVU_RS10515	COG1418	mRNA catabolic process
BVU_RS10540	COG0602	queuosine metabolic process
BVU_RS10560	COG1115	amino acid carrier protein
BVU_RS10570	COG0745	RESPONSE REGULATOR receiver
BVU_RS10570	COG3292	Two component regulator propeller
BVU_RS10570	COG2205	protein histidine kinase activity
BVU_RS10580	COG3681	Belongs to the UPF0597 family
BVU_RS10600	COG4974	Belongs to the 'phage' integrase family
BVU_RS10745	COG3344	reverse transcriptase
BVU_RS10765	COG3344	reverse transcriptase
BVU_RS10845	COG1475	DNA binding
BVU_RS10865	COG2205	protein histidine kinase activity
BVU_RS10865	COG3292	Two component regulator propeller
BVU_RS10865	COG0745	RESPONSE REGULATOR receiver
BVU_RS10880	COG4771	TonB-dependent receptor
BVU_RS10890	COG2755	lipolytic protein G-D-S-L family
BVU_RS10900	COG3250	beta-galactosidase activity
BVU_RS10910	COG3292	Two component regulator propeller
BVU_RS10910	COG2205	protein histidine kinase activity
BVU_RS10910	COG0745	RESPONSE REGULATOR receiver
BVU_RS10920	COG4206	TonB-dependent receptor
BVU_RS10920	COG1629	transport
BVU_RS10925	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS10945	COG3250	beta-galactosidase activity
BVU_RS10955	COG1312	Catalyzes the dehydration of D-mannonate
BVU_RS10960	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS10965	COG2205	protein histidine kinase activity
BVU_RS10965	COG0784	Response regulator, receiver
BVU_RS11040	COG4771	TonB-dependent receptor
BVU_RS11095	COG1629	transport
BVU_RS11095	COG4206	TonB-dependent receptor
BVU_RS11105	COG0126	phosphoglycerate kinase activity
BVU_RS11120	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS11130	COG1595	DNA-templated transcription, initiation
BVU_RS11140	COG0534	Mate efflux family protein
BVU_RS11145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVU_RS11150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVU_RS11175	COG4206	TonB-dependent receptor
BVU_RS11175	COG1629	transport
BVU_RS11185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS11205	COG0745	RESPONSE REGULATOR receiver
BVU_RS11205	COG2205	protein histidine kinase activity
BVU_RS11205	COG3292	Two component regulator propeller
BVU_RS11210	COG4771	TonB-dependent receptor
BVU_RS11245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BVU_RS11260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVU_RS11275	COG0321	lipoyl(octanoyl) transferase activity
BVU_RS11275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVU_RS11280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVU_RS11285	COG1834	amidinotransferase
BVU_RS11295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVU_RS11305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVU_RS11320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVU_RS11335	COG3591	Belongs to the peptidase S1B family
BVU_RS11340	COG3591	Belongs to the peptidase S1B family
BVU_RS11355	COG1408	metallophosphoesterase
BVU_RS11360	COG1410	methionine synthase
BVU_RS11360	COG0646	methionine synthase
BVU_RS11365	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BVU_RS11370	COG0463	Glycosyl transferase, family 2
BVU_RS11420	COG2311	Membrane
BVU_RS11425	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVU_RS11435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVU_RS11455	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVU_RS11470	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BVU_RS11475	COG1032	radical SAM domain protein
BVU_RS11490	COG5434	Belongs to the glycosyl hydrolase 28 family
BVU_RS11520	COG2264	protein methyltransferase activity
BVU_RS11565	COG0582	viral genome integration into host DNA
BVU_RS11610	COG0673	inositol 2-dehydrogenase activity
BVU_RS11615	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BVU_RS11660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVU_RS11670	COG2160	L-arabinose isomerase activity
BVU_RS11695	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BVU_RS11715	COG0484	heat shock protein binding
BVU_RS11720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVU_RS11725	COG0488	(ABC) transporter
BVU_RS11745	COG0393	Putative heavy-metal-binding
BVU_RS11780	COG1705	Flagellar rod assembly protein muramidase FlgJ
BVU_RS11780	COG1388	LysM domain
BVU_RS11790	COG0577	efflux transmembrane transporter activity
BVU_RS11800	COG1136	(ABC) transporter
BVU_RS11805	COG1136	(ABC) transporter
BVU_RS11805	COG0577	efflux transmembrane transporter activity
BVU_RS11815	COG0577	efflux transmembrane transporter activity
BVU_RS11815	COG1136	(ABC) transporter
BVU_RS11840	COG2204	response regulator
BVU_RS11845	COG4191	Histidine kinase
BVU_RS11860	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BVU_RS11865	COG0572	uridine kinase
BVU_RS11880	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVU_RS11885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVU_RS11890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVU_RS11895	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVU_RS11895	COG0131	Imidazoleglycerol-phosphate dehydratase
BVU_RS11910	COG1592	Rubrerythrin
BVU_RS11910	COG1773	rubredoxin
BVU_RS11920	COG3118	belongs to the thioredoxin family
BVU_RS11935	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVU_RS11945	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BVU_RS11950	COG0157	Belongs to the NadC ModD family
BVU_RS11960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BVU_RS11965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVU_RS11985	COG0443	Heat shock 70 kDa protein
BVU_RS12055	COG1216	Glycosyl transferase, family 2
BVU_RS12060	COG0438	transferase activity, transferring glycosyl groups
BVU_RS12075	COG0438	transferase activity, transferring glycosyl groups
BVU_RS12095	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BVU_RS12150	COG0556	nucleotide-excision repair
BVU_RS12170	COG4948	Mandelate Racemase Muconate Lactonizing
BVU_RS12175	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BVU_RS12180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BVU_RS12185	COG1169	isochorismate synthase
BVU_RS12190	COG2050	protein possibly involved in aromatic compounds catabolism
BVU_RS12195	COG0534	Mate efflux family protein
BVU_RS12200	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVU_RS12215	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVU_RS12225	COG4771	TonB-dependent receptor
BVU_RS12235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS12245	COG4771	TonB-dependent receptor
BVU_RS12265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BVU_RS12280	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BVU_RS12285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BVU_RS12290	COG0569	domain protein
BVU_RS12305	COG1760	l-serine dehydratase
BVU_RS12320	COG4771	TonB-dependent receptor
BVU_RS12335	COG1193	negative regulation of DNA recombination
BVU_RS12410	COG0358	DNA primase activity
BVU_RS12435	COG4974	Belongs to the 'phage' integrase family
BVU_RS12445	COG2003	Belongs to the UPF0758 family
BVU_RS12460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVU_RS12500	COG2755	lipolytic protein G-D-S-L family
BVU_RS12500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BVU_RS12510	COG2217	Heavy metal translocating P-type atpase
BVU_RS12520	COG4221	oxidoreductase activity
BVU_RS12530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BVU_RS12535	COG0511	ligase activity, forming carbon-carbon bonds
BVU_RS12545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVU_RS12560	COG0778	Nitroreductase
BVU_RS12575	COG0561	phosphatase activity
BVU_RS12580	COG0424	maF-like protein
BVU_RS12585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVU_RS12600	COG2814	Major facilitator Superfamily
BVU_RS12605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS12725	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVU_RS12730	COG0646	methionine synthase
BVU_RS12730	COG1410	methionine synthase
BVU_RS12735	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVU_RS12745	COG2233	PERMEase
BVU_RS12750	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVU_RS12765	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BVU_RS12765	COG0778	Nitroreductase
BVU_RS12775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVU_RS12780	COG1704	LemA family
BVU_RS12795	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVU_RS12800	COG2226	methyltransferase
BVU_RS12805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BVU_RS12810	COG1702	phosphate starvation-inducible protein PhoH
BVU_RS12820	COG0101	tRNA pseudouridine synthase activity
BVU_RS12835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS12840	COG1629	transport
BVU_RS12840	COG4206	TonB-dependent receptor
BVU_RS12850	COG1047	Peptidyl-prolyl cis-trans
BVU_RS12860	COG0129	dihydroxy-acid dehydratase activity
BVU_RS12865	COG0028	Belongs to the TPP enzyme family
BVU_RS12880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVU_RS12895	COG1253	flavin adenine dinucleotide binding
BVU_RS12915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BVU_RS12930	COG0653	protein targeting
BVU_RS12960	COG0525	valine-tRNA ligase activity
BVU_RS12965	COG3956	TIGRFAM MazG family protein
BVU_RS12975	COG4206	TonB-dependent receptor
BVU_RS12975	COG1629	transport
BVU_RS12990	COG1595	DNA-templated transcription, initiation
BVU_RS12995	COG1234	tRNA 3'-trailer cleavage
BVU_RS13020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BVU_RS13035	COG3275	phosphorelay sensor kinase activity
BVU_RS13075	COG1215	transferase activity, transferring glycosyl groups
BVU_RS13080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BVU_RS13090	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVU_RS13115	COG1011	Hydrolase
BVU_RS13120	COG0738	Major facilitator superfamily
BVU_RS13155	COG0708	Exodeoxyribonuclease III
BVU_RS13165	COG1741	Belongs to the pirin family
BVU_RS13180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVU_RS13190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVU_RS13210	COG0793	Belongs to the peptidase S41A family
BVU_RS13215	COG2131	deaminase
BVU_RS13225	COG0339	signal peptide processing
BVU_RS13245	COG1971	Probably functions as a manganese efflux pump
BVU_RS13260	COG0463	Glycosyl transferase, family 2
BVU_RS13275	COG0514	ATP-dependent DNA helicase (RecQ)
BVU_RS13285	COG0148	phosphopyruvate hydratase activity
BVU_RS13295	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BVU_RS13305	COG3408	Glycogen debranching enzyme
BVU_RS13335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS13340	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BVU_RS13345	COG1216	Glycosyl transferase, family 2
BVU_RS13350	COG0463	Glycosyl transferase, family 2
BVU_RS13365	COG0297	glycogen (starch) synthase activity
BVU_RS13385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVU_RS13400	COG4641	Protein conserved in bacteria
BVU_RS13400	COG1388	LysM domain
BVU_RS13450	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVU_RS13520	COG3250	beta-galactosidase activity
BVU_RS13525	COG0490	domain, Protein
BVU_RS13525	COG2985	domain, Protein
BVU_RS13530	COG1629	transport
BVU_RS13530	COG4206	TonB-dependent receptor
BVU_RS13540	COG4771	TonB-dependent receptor
BVU_RS13550	COG3250	beta-galactosidase activity
BVU_RS13555	COG3250	beta-galactosidase activity
BVU_RS13560	COG3940	Belongs to the glycosyl hydrolase 43 family
BVU_RS13585	COG0598	Magnesium transport protein CorA
BVU_RS13590	COG1522	sequence-specific DNA binding
BVU_RS13600	COG0586	Pfam SNARE associated Golgi protein
BVU_RS13610	COG0306	phosphate transporter
BVU_RS13620	COG4771	TonB-dependent receptor
BVU_RS13630	COG2873	o-acetylhomoserine
BVU_RS13635	COG1620	l-lactate permease
BVU_RS13645	COG2205	protein histidine kinase activity
BVU_RS13675	COG0668	transmembrane transport
BVU_RS13680	COG0318	PFAM AMP-dependent synthetase and ligase
BVU_RS13690	COG0307	riboflavin synthase, alpha
BVU_RS13695	COG1295	ribonuclease BN
BVU_RS13705	COG0484	heat shock protein binding
BVU_RS13710	COG0784	Response regulator, receiver
BVU_RS13710	COG2205	protein histidine kinase activity
BVU_RS13710	COG5002	protein histidine kinase activity
BVU_RS13715	COG0737	Belongs to the 5'-nucleotidase family
BVU_RS13725	COG4771	TonB-dependent receptor
BVU_RS13745	COG3408	Glycogen debranching enzyme
BVU_RS13760	COG5002	protein histidine kinase activity
BVU_RS13760	COG0784	Response regulator, receiver
BVU_RS13770	COG3059	membrane
BVU_RS13775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVU_RS13780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVU_RS13800	COG1914	H( )-stimulated, divalent metal cation uptake system
BVU_RS13805	COG3263	regulation of cellular component size
BVU_RS13810	COG0534	Mate efflux family protein
BVU_RS13820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BVU_RS13830	COG0488	(ABC) transporter
BVU_RS13855	COG0228	four-way junction DNA binding
BVU_RS13865	COG2755	lipolytic protein G-D-S-L family
BVU_RS13865	COG0657	acetylesterase activity
BVU_RS13890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVU_RS13895	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVU_RS13930	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVU_RS13935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVU_RS13935	COG1333	cytochrome c biogenesis protein
BVU_RS13955	COG1730	sister chromatid segregation
BVU_RS13960	COG0705	Rhomboid family
BVU_RS13970	COG0438	transferase activity, transferring glycosyl groups
BVU_RS13985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVU_RS13985	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVU_RS13990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BVU_RS13990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVU_RS14005	COG2226	methyltransferase
BVU_RS14020	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVU_RS14025	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVU_RS14030	COG1119	ATPase activity
BVU_RS14035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVU_RS14040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVU_RS14050	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BVU_RS14055	COG0252	asparaginase activity
BVU_RS14070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BVU_RS14075	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVU_RS14080	COG0363	glucosamine-6-phosphate deaminase activity
BVU_RS14090	COG1271	oxidase subunit
BVU_RS14105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS14110	COG1136	(ABC) transporter
BVU_RS14115	COG1136	(ABC) transporter
BVU_RS14115	COG0577	efflux transmembrane transporter activity
BVU_RS14125	COG3279	Response regulator of the LytR AlgR family
BVU_RS14170	COG4974	Belongs to the 'phage' integrase family
BVU_RS14350	COG0582	viral genome integration into host DNA
BVU_RS14400	COG1061	Type III restriction enzyme res subunit
BVU_RS14415	COG0629	single-stranded DNA binding
BVU_RS14425	COG4712	double-strand break repair protein
BVU_RS14500	COG4566	intracellular signal transduction
BVU_RS14505	COG0247	lactate metabolic process
BVU_RS14510	COG1139	Iron-sulfur cluster binding protein
BVU_RS14520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BVU_RS14555	COG1918	ferrous iron import across plasma membrane
BVU_RS14555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVU_RS14570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVU_RS14575	COG0497	DNA recombination
BVU_RS14605	COG0297	glycogen (starch) synthase activity
BVU_RS14610	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BVU_RS14615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BVU_RS14625	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BVU_RS14635	COG2816	NAD+ diphosphatase activity
BVU_RS14640	COG2183	response to ionizing radiation
BVU_RS14675	COG3250	beta-galactosidase activity
BVU_RS14680	COG3292	Two component regulator propeller
BVU_RS14680	COG2205	protein histidine kinase activity
BVU_RS14680	COG0745	RESPONSE REGULATOR receiver
BVU_RS14690	COG1629	transport
BVU_RS14690	COG4206	TonB-dependent receptor
BVU_RS14730	COG4771	TonB-dependent receptor
BVU_RS14745	COG4771	TonB-dependent receptor
BVU_RS14775	COG5012	cobalamin binding
BVU_RS14780	COG1501	Belongs to the glycosyl hydrolase 31 family
BVU_RS14795	COG0251	oxidation-reduction process
BVU_RS14820	COG0488	(ABC) transporter
BVU_RS14880	COG1216	Glycosyl transferase, family 2
BVU_RS14880	COG1442	glycosyl transferase family 8
BVU_RS14895	COG3475	LICD family
BVU_RS14905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS14970	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BVU_RS14980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVU_RS14995	COG1678	Uncharacterized ACR, COG1678
BVU_RS15025	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BVU_RS15030	COG1151	hydroxylamine reductase activity
BVU_RS15040	COG3119	arylsulfatase activity
BVU_RS15050	COG0745	RESPONSE REGULATOR receiver
BVU_RS15055	COG5002	protein histidine kinase activity
BVU_RS15075	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVU_RS15080	COG0248	Ppx GppA phosphatase
BVU_RS15090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVU_RS15105	COG0356	it plays a direct role in the translocation of protons across the membrane
BVU_RS15110	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVU_RS15115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVU_RS15120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVU_RS15125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVU_RS15130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVU_RS15145	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BVU_RS15155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BVU_RS15160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVU_RS15175	COG3973	AAA domain
BVU_RS15195	COG1979	alcohol dehydrogenase
BVU_RS15200	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BVU_RS15215	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVU_RS15215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVU_RS15220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVU_RS15225	COG0357	Ribosomal RNA small subunit methyltransferase G
BVU_RS15235	COG2217	Heavy metal translocating P-type atpase
BVU_RS15250	COG0321	lipoyl(octanoyl) transferase activity
BVU_RS15255	COG1022	Amp-dependent synthetase and ligase
BVU_RS15285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BVU_RS15290	COG1523	belongs to the glycosyl hydrolase 13 family
BVU_RS15295	COG1312	Catalyzes the dehydration of D-mannonate
BVU_RS15300	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVU_RS15305	COG2176	DNA-directed DNA polymerase activity
BVU_RS15310	COG1739	Uncharacterized protein family UPF0029
BVU_RS15320	COG0556	nucleotide-excision repair
BVU_RS15345	COG1388	LysM domain
BVU_RS15345	COG3942	CHAP domain
BVU_RS15355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVU_RS15360	COG3104	oligopeptide transport
BVU_RS15365	COG2431	L-lysine efflux transmembrane transporter activity
BVU_RS15380	COG1757	Na H antiporter
BVU_RS15385	COG2721	sulfolactate sulfo-lyase activity
BVU_RS15390	COG1609	Transcriptional regulator
BVU_RS15405	COG0501	Belongs to the peptidase M48B family
BVU_RS15415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVU_RS15425	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVU_RS15440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVU_RS15480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BVU_RS15495	COG1904	glucuronate isomerase
BVU_RS15500	COG0246	Mannitol dehydrogenase
BVU_RS15525	COG1120	ATPase activity
BVU_RS15530	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BVU_RS15560	COG4804	nuclease activity
BVU_RS15570	COG0662	Cupin 2, conserved barrel domain protein
BVU_RS15570	COG2207	Transcriptional regulator
BVU_RS15575	COG4753	response regulator
BVU_RS15575	COG2207	Transcriptional regulator
BVU_RS15580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVU_RS15590	COG4771	TonB-dependent receptor
BVU_RS15605	COG4771	TonB-dependent receptor
BVU_RS15610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVU_RS15615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVU_RS15620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVU_RS15640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVU_RS15650	COG0439	Biotin carboxylase
BVU_RS15675	COG4771	TonB-dependent receptor
BVU_RS15680	COG4771	TonB-dependent receptor
BVU_RS15695	COG1797	cobyrinic acid a,c-diamide synthase activity
BVU_RS15700	COG2096	Adenosyltransferase
BVU_RS15705	COG1492	cobalamin metabolic process
BVU_RS15715	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BVU_RS15725	COG4974	Belongs to the 'phage' integrase family
BVU_RS15885	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BVU_RS15920	COG0513	Belongs to the DEAD box helicase family
BVU_RS15925	COG0560	Phosphoserine phosphatase
BVU_RS15925	COG3830	Belongs to the UPF0237 family
BVU_RS15935	COG1011	Hydrolase
BVU_RS15945	COG0343	queuine tRNA-ribosyltransferase activity
BVU_RS15950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVU_RS15955	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BVU_RS15960	COG1597	lipid kinase activity
BVU_RS15965	COG0156	8-amino-7-oxononanoate synthase activity
BVU_RS15970	COG0697	spore germination
BVU_RS15980	COG1136	(ABC) transporter
BVU_RS16015	COG2204	response regulator
BVU_RS16020	COG3852	Histidine kinase
BVU_RS16030	COG4974	Belongs to the 'phage' integrase family
BVU_RS16060	COG2003	Belongs to the UPF0758 family
BVU_RS16075	COG1342	Belongs to the UPF0251 family
BVU_RS16095	COG1484	DNA-dependent DNA replication
BVU_RS16165	COG0668	transmembrane transport
BVU_RS16175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVU_RS16195	COG0716	FMN binding
BVU_RS16210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVU_RS16215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVU_RS16245	COG1757	Na H antiporter
BVU_RS16250	COG3579	cysteine-type endopeptidase activity
BVU_RS16275	COG1805	sodium ion transport
BVU_RS16280	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVU_RS16285	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVU_RS16290	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BVU_RS16300	COG0513	Belongs to the DEAD box helicase family
BVU_RS16305	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVU_RS16310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVU_RS16325	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS16340	COG0561	phosphatase activity
BVU_RS16350	COG1285	pathogenesis
BVU_RS16360	COG2205	protein histidine kinase activity
BVU_RS16370	COG0494	nUDIX hydrolase
BVU_RS16375	COG4106	trans-aconitate 2-methyltransferase activity
BVU_RS16390	COG3387	PFAM Glycoside hydrolase 15-related
BVU_RS16420	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BVU_RS16425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVU_RS16430	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVU_RS16435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BVU_RS16440	COG2204	response regulator
BVU_RS16450	COG4176	ABC-type proline glycine betaine transport system permease component
BVU_RS16460	COG0697	spore germination
BVU_RS16465	COG0110	maltose O-acetyltransferase activity
BVU_RS16475	COG0024	Methionine aminopeptidase
BVU_RS16480	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVU_RS16490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVU_RS16495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVU_RS16500	COG0552	protein localization to endoplasmic reticulum
BVU_RS16505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVU_RS16510	COG0776	regulation of translation
BVU_RS16515	COG0776	regulation of translation
BVU_RS16520	COG0714	Associated with various cellular activities
BVU_RS16535	COG2304	oxidoreductase activity
BVU_RS16560	COG0671	phosphoesterase, PA-phosphatase related
BVU_RS16590	COG0542	response to heat
BVU_RS16600	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVU_RS16620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVU_RS16625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVU_RS16630	COG0336	Belongs to the RNA methyltransferase TrmD family
BVU_RS16635	COG0167	dihydroorotate dehydrogenase activity
BVU_RS16640	COG0543	2 iron, 2 sulfur cluster binding
BVU_RS16655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVU_RS16670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVU_RS16680	COG0390	transport system, permease component
BVU_RS16685	COG1131	(ABC) transporter
BVU_RS16690	COG0442	prolyl-tRNA aminoacylation
BVU_RS16700	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVU_RS16715	COG0483	inositol monophosphate 1-phosphatase activity
BVU_RS16730	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVU_RS16750	COG0842	Transport permease protein
BVU_RS16750	COG1129	ABC transporter
BVU_RS16755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVU_RS16775	COG0540	Belongs to the ATCase OTCase family
BVU_RS16780	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BVU_RS16795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVU_RS16800	COG0534	Mate efflux family protein
BVU_RS16805	COG2885	chlorophyll binding
BVU_RS16810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVU_RS16855	COG0504	CTP synthase activity
BVU_RS16860	COG0706	membrane insertase activity
BVU_RS16865	COG1506	peptidase
BVU_RS16865	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS16870	COG0564	pseudouridine synthase activity
BVU_RS16875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVU_RS16880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVU_RS16880	COG0574	Belongs to the PEP-utilizing enzyme family
BVU_RS16915	COG1192	Involved in chromosome partitioning
BVU_RS16950	COG3344	reverse transcriptase
BVU_RS17035	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVU_RS17100	COG1192	Involved in chromosome partitioning
BVU_RS17125	COG0758	DNA mediated transformation
BVU_RS17140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVU_RS17210	COG1396	sequence-specific DNA binding
BVU_RS17220	COG0776	regulation of translation
BVU_RS17250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVU_RS17265	COG1136	(ABC) transporter
BVU_RS17265	COG0577	efflux transmembrane transporter activity
BVU_RS17275	COG0339	signal peptide processing
BVU_RS17295	COG0438	transferase activity, transferring glycosyl groups
BVU_RS17310	COG1216	Glycosyl transferase, family 2
BVU_RS17375	COG0386	Belongs to the glutathione peroxidase family
BVU_RS17395	COG4191	Histidine kinase
BVU_RS17400	COG1074	ATP-dependent DNA helicase activity
BVU_RS17410	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BVU_RS17415	COG0305	Participates in initiation and elongation during chromosome replication
BVU_RS17420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVU_RS17420	COG0072	phenylalanine-tRNA ligase activity
BVU_RS17425	COG0217	transcriptional regulatory protein
BVU_RS17490	COG1192	Involved in chromosome partitioning
BVU_RS17505	COG3177	Filamentation induced by cAMP protein fic
BVU_RS17545	COG4771	TonB-dependent receptor
BVU_RS17550	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVU_RS17595	COG0561	phosphatase activity
BVU_RS17610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVU_RS17615	COG0248	Ppx GppA phosphatase
BVU_RS17630	COG0058	SHG alpha-glucan phosphorylase activity
BVU_RS17635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVU_RS17635	COG4651	solute:proton antiporter activity
BVU_RS17640	COG0205	6-phosphofructokinase activity
BVU_RS17645	COG1595	DNA-templated transcription, initiation
BVU_RS17655	COG0588	phosphoglycerate mutase activity
BVU_RS17660	COG1830	Aldolase
BVU_RS17670	COG2095	MarC family integral membrane protein
BVU_RS17685	COG0577	efflux transmembrane transporter activity
BVU_RS17690	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVU_RS17690	COG1136	(ABC) transporter
BVU_RS17710	COG3852	Histidine kinase
BVU_RS17715	COG3153	acetyltransferase
BVU_RS17715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVU_RS17780	COG0352	thiamine-phosphate diphosphorylase activity
BVU_RS17785	COG2022	thiamine diphosphate biosynthetic process
BVU_RS17790	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BVU_RS17810	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVU_RS17815	COG0754	glutathionylspermidine amidase activity
BVU_RS17825	COG0352	thiamine-phosphate diphosphorylase activity
BVU_RS17830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVU_RS17845	COG1177	transmembrane transport
BVU_RS17850	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVU_RS17860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS17875	COG0058	SHG alpha-glucan phosphorylase activity
BVU_RS17885	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVU_RS17890	COG1269	ATP hydrolysis coupled proton transport
BVU_RS17905	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BVU_RS17955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS17985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVU_RS17990	COG1597	lipid kinase activity
BVU_RS17995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVU_RS18005	COG1970	mechanosensitive ion channel activity
BVU_RS18010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVU_RS18010	COG0519	Catalyzes the synthesis of GMP from XMP
BVU_RS18015	COG0519	Catalyzes the synthesis of GMP from XMP
BVU_RS18080	COG1012	belongs to the aldehyde dehydrogenase family
BVU_RS18100	COG1136	(ABC) transporter
BVU_RS18100	COG0577	efflux transmembrane transporter activity
BVU_RS18120	COG2211	Major facilitator Superfamily
BVU_RS18165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BVU_RS18180	COG1674	ftsk spoiiie
BVU_RS18190	COG0492	ferredoxin-NADP+ reductase activity
BVU_RS18195	COG0612	Peptidase, M16
BVU_RS18205	COG1131	(ABC) transporter
BVU_RS18210	COG0791	NLP P60 protein
BVU_RS18220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BVU_RS18225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVU_RS18240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVU_RS18250	COG0543	2 iron, 2 sulfur cluster binding
BVU_RS18275	COG0037	tRNA processing
BVU_RS18290	COG4864	UPF0365 protein
BVU_RS18295	COG0813	purine-nucleoside phosphorylase activity
BVU_RS18300	COG1956	GAF domain-containing protein
BVU_RS18305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVU_RS18350	COG3328	transposase activity
BVU_RS18390	COG4942	peptidase
BVU_RS18440	COG0582	viral genome integration into host DNA
BVU_RS18465	COG2433	Pfam Transposase IS66
BVU_RS18490	COG3645	SOS response
BVU_RS18500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVU_RS18530	COG3550	peptidyl-serine autophosphorylation
BVU_RS18565	COG1475	DNA binding
BVU_RS18570	COG3969	phosphoadenosine phosphosulfate
BVU_RS18605	COG4206	TonB-dependent receptor
BVU_RS18605	COG1629	transport
BVU_RS18610	COG0702	epimerase
BVU_RS18650	COG4974	Belongs to the 'phage' integrase family
BVU_RS18675	COG3340	Belongs to the peptidase S51 family
BVU_RS18725	COG4974	Belongs to the 'phage' integrase family
BVU_RS18775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVU_RS18800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVU_RS18805	COG0535	radical SAM domain protein
BVU_RS18825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVU_RS18900	COG1063	alcohol dehydrogenase
BVU_RS18915	COG1028	Short-chain dehydrogenase reductase Sdr
BVU_RS18920	COG0346	lactoylglutathione lyase activity
BVU_RS18945	COG0564	pseudouridine synthase activity
BVU_RS18950	COG0534	Mate efflux family protein
BVU_RS18970	COG1538	Outer membrane efflux protein
BVU_RS19050	COG3279	Response regulator of the LytR AlgR family
BVU_RS19070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVU_RS19080	COG0739	heme binding
BVU_RS19085	COG0686	Belongs to the AlaDH PNT family
BVU_RS19090	COG0805	protein transport
BVU_RS19095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVU_RS19115	COG2855	membrane
BVU_RS19120	COG0583	DNA-binding transcription factor activity
BVU_RS19130	COG0542	response to heat
BVU_RS19160	COG1862	Preprotein translocase
BVU_RS19165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVU_RS19175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BVU_RS19180	COG0193	aminoacyl-tRNA hydrolase activity
BVU_RS19185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BVU_RS19195	COG0475	glutathione-regulated potassium exporter activity
BVU_RS19200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BVU_RS19205	COG2195	Cleaves the N-terminal amino acid of tripeptides
BVU_RS19210	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVU_RS19215	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVU_RS19225	COG3292	Two component regulator propeller
BVU_RS19225	COG0745	RESPONSE REGULATOR receiver
BVU_RS19225	COG2205	protein histidine kinase activity
BVU_RS19240	COG5146	pantothenate kinase activity
BVU_RS19280	COG3250	beta-galactosidase activity
BVU_RS19310	COG0788	formyltetrahydrofolate deformylase activity
BVU_RS19320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BVU_RS19325	COG0107	imidazoleglycerol-phosphate synthase activity
BVU_RS19330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVU_RS19330	COG0140	phosphoribosyl-ATP diphosphatase activity
BVU_RS19335	COG2884	Cell division ATP-binding protein ftsE
BVU_RS19340	COG0527	aspartate kinase activity
BVU_RS19345	COG0019	diaminopimelate decarboxylase activity
BVU_RS19375	COG2431	L-lysine efflux transmembrane transporter activity
BVU_RS19380	COG4591	ABC-type transport system involved in lipoprotein release permease component
BVU_RS19385	COG0436	Aminotransferase
BVU_RS19400	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BVU_RS19405	COG0167	dihydroorotate dehydrogenase activity
BVU_RS19455	COG1027	Aspartate ammonia-lyase
BVU_RS19460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BVU_RS19470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVU_RS19480	COG4657	Part of a membrane complex involved in electron transport
BVU_RS19485	COG4660	Part of a membrane complex involved in electron transport
BVU_RS19490	COG4659	FMN binding
BVU_RS19495	COG4658	electron transport chain
BVU_RS19500	COG4656	Part of a membrane complex involved in electron transport
BVU_RS19515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVU_RS19530	COG0076	glutamate decarboxylase activity
BVU_RS19535	COG2066	Belongs to the glutaminase family
BVU_RS19540	COG3142	Participates in the control of copper homeostasis
BVU_RS19560	COG0531	amino acid
BVU_RS19570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVU_RS19575	COG0481	GTPase activity
BVU_RS19600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVU_RS19605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVU_RS19670	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BVU_RS19690	COG1216	Glycosyl transferase, family 2
BVU_RS19735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVU_RS19740	COG0581	inorganic phosphate transmembrane transporter activity
BVU_RS19745	COG0573	inorganic phosphate transmembrane transporter activity
BVU_RS19750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVU_RS19755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVU_RS19770	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BVU_RS19775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS19780	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BVU_RS19815	COG2115	Belongs to the xylose isomerase family
BVU_RS19830	COG0745	RESPONSE REGULATOR receiver
BVU_RS19830	COG2205	protein histidine kinase activity
BVU_RS19830	COG3292	Two component regulator propeller
BVU_RS19835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVU_RS19855	COG1215	transferase activity, transferring glycosyl groups
BVU_RS19880	COG1216	Glycosyl transferase, family 2
BVU_RS19885	COG1216	Glycosyl transferase, family 2
BVU_RS19905	COG0438	transferase activity, transferring glycosyl groups
BVU_RS19915	COG1215	transferase activity, transferring glycosyl groups
BVU_RS19935	COG0438	transferase activity, transferring glycosyl groups
BVU_RS19945	COG1442	glycosyl transferase family 8
BVU_RS19945	COG1216	Glycosyl transferase, family 2
BVU_RS19950	COG0438	transferase activity, transferring glycosyl groups
BVU_RS19955	COG0463	Glycosyl transferase, family 2
BVU_RS19960	COG0745	RESPONSE REGULATOR receiver
BVU_RS19965	COG2205	protein histidine kinase activity
BVU_RS19965	COG0784	Response regulator, receiver
BVU_RS19980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVU_RS19985	COG0352	thiamine-phosphate diphosphorylase activity
BVU_RS19985	COG0351	phosphomethylpyrimidine kinase
BVU_RS19990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVU_RS20015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVU_RS20020	COG0071	Belongs to the small heat shock protein (HSP20) family
BVU_RS20025	COG0784	Response regulator, receiver
BVU_RS20025	COG2205	protein histidine kinase activity
BVU_RS20035	COG0505	Belongs to the CarA family
BVU_RS20045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVU_RS20055	COG0004	ammonium transporteR
BVU_RS20060	COG0347	Belongs to the P(II) protein family
BVU_RS20070	COG0436	Aminotransferase
BVU_RS20075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVU_RS20080	COG0067	glutamate synthase
BVU_RS20080	COG0069	glutamate synthase activity
BVU_RS20080	COG0070	glutamate synthase
BVU_RS20090	COG0367	asparagine synthase
BVU_RS20140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVU_RS20180	COG1215	transferase activity, transferring glycosyl groups
BVU_RS20185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVU_RS20190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVU_RS20205	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVU_RS20230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVU_RS20240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVU_RS20245	COG1083	cytidylyl-transferase
BVU_RS20250	COG2089	acid synthase
BVU_RS20265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVU_RS20270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVU_RS20330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVU_RS20340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVU_RS20345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVU_RS20350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVU_RS20355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVU_RS20365	COG0242	peptide deformylase activity
BVU_RS20370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVU_RS20385	COG2885	chlorophyll binding
BVU_RS20415	COG1506	peptidase
BVU_RS20415	COG0823	Involved in the tonB-independent uptake of proteins
BVU_RS20415	COG4946	Tricorn protease homolog
BVU_RS20420	COG0477	Major facilitator Superfamily
BVU_RS20420	COG2814	Major facilitator Superfamily
BVU_RS20445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS20490	COG0133	tryptophan synthase activity
BVU_RS20495	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVU_RS20500	COG0512	Glutamine amidotransferase of anthranilate synthase
BVU_RS20505	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVU_RS20510	COG0134	indole-3-glycerol-phosphate synthase activity
BVU_RS20515	COG0135	phosphoribosylanthranilate isomerase activity
BVU_RS20520	COG0159	tryptophan synthase activity
BVU_RS20525	COG0252	asparaginase activity
BVU_RS20530	COG0745	RESPONSE REGULATOR receiver
BVU_RS20535	COG5002	protein histidine kinase activity
BVU_RS20555	COG0629	single-stranded DNA binding
BVU_RS20565	COG0776	regulation of translation
BVU_RS20570	COG1530	ribonuclease E activity
BVU_RS20580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVU_RS20590	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVU_RS20595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BVU_RS20600	COG0166	Belongs to the GPI family
BVU_RS20605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVU_RS20615	COG0702	epimerase
BVU_RS20620	COG4771	TonB-dependent receptor
BVU_RS20635	COG1940	carbohydrate kinase activity
BVU_RS20650	COG2271	Major facilitator Superfamily
BVU_RS20655	COG0363	glucosamine-6-phosphate deaminase activity
BVU_RS20660	COG0363	glucosamine-6-phosphate deaminase activity
BVU_RS20670	COG1917	Cupin 2, conserved barrel domain protein
BVU_RS20670	COG4977	sequence-specific DNA binding
BVU_RS20675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVU_RS20715	COG1131	(ABC) transporter
BVU_RS20725	COG3250	beta-galactosidase activity
BVU_RS20735	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS20740	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
BVU_RS20745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS20765	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BVU_RS20780	COG1629	transport
BVU_RS20780	COG4206	TonB-dependent receptor
BVU_RS20790	COG2502	aspartate--ammonia ligase
BVU_RS20795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BVU_RS20810	COG3876	Protein conserved in bacteria
BVU_RS20825	COG1132	(ABC) transporter
BVU_RS20845	COG0732	type I restriction modification DNA specificity domain
BVU_RS20855	COG0732	type I restriction modification DNA specificity domain
BVU_RS20860	COG4804	nuclease activity
BVU_RS20865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVU_RS20925	COG0110	maltose O-acetyltransferase activity
BVU_RS20945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BVU_RS20980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVU_RS20985	COG0798	PFAM Bile acid sodium symporter
BVU_RS21005	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVU_RS21090	COG1629	transport
BVU_RS21095	COG4206	TonB-dependent receptor
BVU_RS21095	COG1629	transport
BVU_RS21105	COG0546	phosphoglycolate phosphatase activity