locus-tag	class	description
NXW81_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXW81_RS00010	COG0778	Nitroreductase
NXW81_RS00020	COG1640	4-alpha-glucanotransferase
NXW81_RS00040	COG1216	Glycosyl transferase, family 2
NXW81_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW81_RS00055	COG1022	Amp-dependent synthetase and ligase
NXW81_RS00090	COG0359	binds to the 23S rRNA
NXW81_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXW81_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
NXW81_RS00125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXW81_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXW81_RS00165	COG2431	L-lysine efflux transmembrane transporter activity
NXW81_RS00260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW81_RS00260	COG0551	DNA topoisomerase type I activity
NXW81_RS00270	COG4974	Belongs to the 'phage' integrase family
NXW81_RS00495	COG1475	DNA binding
NXW81_RS00500	COG4474	Belongs to the UPF0398 family
NXW81_RS00565	COG1733	regulation of RNA biosynthetic process
NXW81_RS00590	COG4974	Belongs to the 'phage' integrase family
NXW81_RS00600	COG1373	ATPase (AAA superfamily
NXW81_RS00605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXW81_RS00620	COG4206	TonB-dependent receptor
NXW81_RS00620	COG1629	transport
NXW81_RS00635	COG2234	aminopeptidase activity
NXW81_RS00645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXW81_RS00650	COG0802	atpase or kinase
NXW81_RS00665	COG0714	Associated with various cellular activities
NXW81_RS00700	COG3118	belongs to the thioredoxin family
NXW81_RS00710	COG0688	phosphatidylethanolamine metabolic process
NXW81_RS00715	COG1183	phosphatidylcholine synthase activity
NXW81_RS00735	COG0792	nuclease activity
NXW81_RS00750	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXW81_RS00760	COG0534	Mate efflux family protein
NXW81_RS00765	COG0528	UMP kinase activity
NXW81_RS00780	COG3250	beta-galactosidase activity
NXW81_RS00790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW81_RS00795	COG4206	TonB-dependent receptor
NXW81_RS00795	COG1629	transport
NXW81_RS00800	COG2205	protein histidine kinase activity
NXW81_RS00800	COG3292	Two component regulator propeller
NXW81_RS00800	COG0745	RESPONSE REGULATOR receiver
NXW81_RS00810	COG0233	cytoplasmic translational termination
NXW81_RS00815	COG1162	GTPase activity
NXW81_RS00825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXW81_RS00840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXW81_RS00840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXW81_RS00850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXW81_RS00860	COG1629	transport
NXW81_RS00860	COG4206	TonB-dependent receptor
NXW81_RS00865	COG4974	Belongs to the 'phage' integrase family
NXW81_RS00870	COG4771	TonB-dependent receptor
NXW81_RS00880	COG2095	MarC family integral membrane protein
NXW81_RS00895	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXW81_RS00905	COG1435	thymidine kinase activity
NXW81_RS00995	COG0693	protein deglycase activity
NXW81_RS01010	COG0534	Mate efflux family protein
NXW81_RS01080	COG1830	Aldolase
NXW81_RS01085	COG0588	phosphoglycerate mutase activity
NXW81_RS01095	COG1595	DNA-templated transcription, initiation
NXW81_RS01100	COG0205	6-phosphofructokinase activity
NXW81_RS01105	COG0058	SHG alpha-glucan phosphorylase activity
NXW81_RS01110	COG0010	Belongs to the arginase family
NXW81_RS01115	COG4413	Urea transporter
NXW81_RS01120	COG1396	sequence-specific DNA binding
NXW81_RS01130	COG4771	TonB-dependent receptor
NXW81_RS01190	COG2076	Multidrug Resistance protein
NXW81_RS01205	COG0475	glutathione-regulated potassium exporter activity
NXW81_RS01205	COG0589	response to stress
NXW81_RS01230	COG2207	Transcriptional regulator
NXW81_RS01240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXW81_RS01245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXW81_RS01270	COG0110	maltose O-acetyltransferase activity
NXW81_RS01275	COG1522	sequence-specific DNA binding
NXW81_RS01280	COG2873	o-acetylhomoserine
NXW81_RS01290	COG0668	transmembrane transport
NXW81_RS01320	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXW81_RS01325	COG0527	aspartate kinase activity
NXW81_RS01325	COG0460	homoserine dehydrogenase
NXW81_RS01330	COG0252	asparaginase activity
NXW81_RS01340	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXW81_RS01345	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NXW81_RS01355	COG4771	TonB-dependent receptor
NXW81_RS01370	COG0826	peptidase U32
NXW81_RS01375	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXW81_RS01390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXW81_RS01410	COG0519	Catalyzes the synthesis of GMP from XMP
NXW81_RS01425	COG4771	TonB-dependent receptor
NXW81_RS01465	COG1131	(ABC) transporter
NXW81_RS01480	COG5002	protein histidine kinase activity
NXW81_RS01485	COG2205	protein histidine kinase activity
NXW81_RS01495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXW81_RS01500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NXW81_RS01505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXW81_RS01555	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS01585	COG4771	TonB-dependent receptor
NXW81_RS01600	COG0471	metal ion transport
NXW81_RS01610	COG3292	Two component regulator propeller
NXW81_RS01610	COG2205	protein histidine kinase activity
NXW81_RS01610	COG0745	RESPONSE REGULATOR receiver
NXW81_RS01610	COG3292	Two component regulator propeller
NXW81_RS01610	COG0745	RESPONSE REGULATOR receiver
NXW81_RS01610	COG2205	protein histidine kinase activity
NXW81_RS01640	COG0702	epimerase
NXW81_RS01645	COG4771	TonB-dependent receptor
NXW81_RS01670	COG0616	signal peptide processing
NXW81_RS01675	COG1663	tetraacyldisaccharide 4'-kinase activity
NXW81_RS01680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXW81_RS01685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXW81_RS01705	COG0513	Belongs to the DEAD box helicase family
NXW81_RS01710	COG2070	2-Nitropropane dioxygenase
NXW81_RS01715	COG0724	RNA recognition motif
NXW81_RS01730	COG3973	AAA domain
NXW81_RS01745	COG4974	Belongs to the 'phage' integrase family
NXW81_RS01750	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NXW81_RS01875	COG1216	Glycosyl transferase, family 2
NXW81_RS01875	COG1442	glycosyl transferase family 8
NXW81_RS01890	COG1216	Glycosyl transferase, family 2
NXW81_RS01895	COG1216	Glycosyl transferase, family 2
NXW81_RS01895	COG1442	glycosyl transferase family 8
NXW81_RS01910	COG1216	Glycosyl transferase, family 2
NXW81_RS01930	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS01945	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS01950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXW81_RS02015	COG4988	ABC transporter
NXW81_RS02125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXW81_RS02190	COG2204	response regulator
NXW81_RS02195	COG0446	pyridine nucleotide-disulphide oxidoreductase
NXW81_RS02215	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS02220	COG0737	Belongs to the 5'-nucleotidase family
NXW81_RS02225	COG0737	Belongs to the 5'-nucleotidase family
NXW81_RS02230	COG0335	large ribosomal subunit rRNA binding
NXW81_RS02240	COG1136	(ABC) transporter
NXW81_RS02240	COG0577	efflux transmembrane transporter activity
NXW81_RS02245	COG1136	(ABC) transporter
NXW81_RS02245	COG0577	efflux transmembrane transporter activity
NXW81_RS02250	COG1136	(ABC) transporter
NXW81_RS02250	COG0577	efflux transmembrane transporter activity
NXW81_RS02265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXW81_RS02265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXW81_RS02280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXW81_RS02295	COG2996	Protein conserved in bacteria
NXW81_RS02300	COG0039	L-malate dehydrogenase activity
NXW81_RS02310	COG2217	Heavy metal translocating P-type atpase
NXW81_RS02325	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXW81_RS02330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXW81_RS02335	COG0509	glycine decarboxylation via glycine cleavage system
NXW81_RS02350	COG0006	proline dipeptidase activity
NXW81_RS02355	COG3458	cephalosporin-C deacetylase activity
NXW81_RS02370	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXW81_RS02375	COG1773	rubredoxin
NXW81_RS02385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXW81_RS02390	COG1011	Hydrolase
NXW81_RS02395	COG0196	riboflavin kinase activity
NXW81_RS02400	COG1266	CAAX protease self-immunity
NXW81_RS02405	COG2166	iron-sulfur cluster assembly
NXW81_RS02410	COG2234	aminopeptidase activity
NXW81_RS02415	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXW81_RS02420	COG0280	phosphate acetyltransferase
NXW81_RS02425	COG3426	butyrate kinase activity
NXW81_RS02450	COG1185	polyribonucleotide nucleotidyltransferase activity
NXW81_RS02460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXW81_RS02480	COG0076	glutamate decarboxylase activity
NXW81_RS02485	COG2066	Belongs to the glutaminase family
NXW81_RS02495	COG0531	amino acid
NXW81_RS02505	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW81_RS02595	COG0740	serine-type endopeptidase activity
NXW81_RS02745	COG3345	alpha-galactosidase
NXW81_RS02765	COG1131	(ABC) transporter
NXW81_RS02845	COG0667	Aldo Keto reductase
NXW81_RS02890	COG1696	Membrane protein involved in D-alanine export
NXW81_RS02925	COG1309	transcriptional regulator
NXW81_RS02930	COG2986	histidine ammonia-lyase
NXW81_RS02940	COG1228	amidohydrolase
NXW81_RS02950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXW81_RS02960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXW81_RS02975	COG0203	ribosomal protein L17
NXW81_RS02980	COG0202	RNA polymerase activity
NXW81_RS02985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXW81_RS02990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXW81_RS02995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXW81_RS03000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXW81_RS03005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXW81_RS03020	COG0200	Binds to the 23S rRNA
NXW81_RS03025	COG1841	ribosomal large subunit assembly
NXW81_RS03030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NXW81_RS03035	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXW81_RS03040	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXW81_RS03045	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXW81_RS03050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXW81_RS03055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXW81_RS03060	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXW81_RS03065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXW81_RS03070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXW81_RS03075	COG0255	Belongs to the universal ribosomal protein uL29 family
NXW81_RS03080	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXW81_RS03085	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXW81_RS03090	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXW81_RS03095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXW81_RS03100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXW81_RS03105	COG0089	rRNA binding
NXW81_RS03110	COG0088	Forms part of the polypeptide exit tunnel
NXW81_RS03115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXW81_RS03120	COG0051	transcription antitermination factor activity, RNA binding
NXW81_RS03125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXW81_RS03130	COG0049	tRNA binding
NXW81_RS03135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXW81_RS03145	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXW81_RS03150	COG0085	RNA polymerase activity
NXW81_RS03155	COG0222	ribosome binding
NXW81_RS03160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXW81_RS03165	COG0081	regulation of translation
NXW81_RS03170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXW81_RS03180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXW81_RS03190	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXW81_RS03220	COG4974	Belongs to the 'phage' integrase family
NXW81_RS03225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXW81_RS03230	COG0006	proline dipeptidase activity
NXW81_RS03235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXW81_RS03245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXW81_RS03255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXW81_RS03265	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXW81_RS03285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW81_RS03290	COG1027	Aspartate ammonia-lyase
NXW81_RS03295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXW81_RS03300	COG0252	asparaginase activity
NXW81_RS03310	COG4804	nuclease activity
NXW81_RS03315	COG2205	protein histidine kinase activity
NXW81_RS03315	COG3292	Two component regulator propeller
NXW81_RS03315	COG0745	RESPONSE REGULATOR receiver
NXW81_RS03320	COG0584	glycerophosphoryl diester phosphodiesterase
NXW81_RS03345	COG4206	TonB-dependent receptor
NXW81_RS03345	COG1629	transport
NXW81_RS03355	COG3940	Belongs to the glycosyl hydrolase 43 family
NXW81_RS03400	COG2096	Adenosyltransferase
NXW81_RS03445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW81_RS03450	COG0793	Belongs to the peptidase S41A family
NXW81_RS03455	COG2205	protein histidine kinase activity
NXW81_RS03455	COG0784	Response regulator, receiver
NXW81_RS03455	COG5002	protein histidine kinase activity
NXW81_RS03460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXW81_RS03490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXW81_RS03495	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXW81_RS03510	COG2059	Chromate
NXW81_RS03525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXW81_RS03530	COG1396	sequence-specific DNA binding
NXW81_RS03535	COG0318	PFAM AMP-dependent synthetase and ligase
NXW81_RS03540	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXW81_RS03540	COG0662	Cupin 2, conserved barrel domain protein
NXW81_RS03565	COG1040	competence protein
NXW81_RS03610	COG2610	gluconate transmembrane transporter activity
NXW81_RS03615	COG1929	Belongs to the glycerate kinase type-1 family
NXW81_RS03635	COG1629	transport
NXW81_RS03640	COG1609	Transcriptional regulator
NXW81_RS03645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW81_RS03650	COG1629	transport
NXW81_RS03650	COG4206	TonB-dependent receptor
NXW81_RS03680	COG3693	PFAM glycoside hydrolase, family 10
NXW81_RS03680	COG2382	esterase
NXW81_RS03700	COG3634	alkyl hydroperoxide reductase activity
NXW81_RS03710	COG2816	NAD+ diphosphatase activity
NXW81_RS03730	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS03750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NXW81_RS03760	COG3250	beta-galactosidase activity
NXW81_RS03785	COG1629	transport
NXW81_RS03810	COG0745	RESPONSE REGULATOR receiver
NXW81_RS03810	COG2205	protein histidine kinase activity
NXW81_RS03810	COG3292	Two component regulator propeller
NXW81_RS03830	COG0018	arginyl-trna synthetase
NXW81_RS03840	COG0705	Rhomboid family
NXW81_RS03855	COG0339	signal peptide processing
NXW81_RS03860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXW81_RS03870	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXW81_RS03870	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXW81_RS03875	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXW81_RS03895	COG3250	beta-galactosidase activity
NXW81_RS03905	COG3345	alpha-galactosidase
NXW81_RS03910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW81_RS03915	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS03950	COG4771	TonB-dependent receptor
NXW81_RS03965	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXW81_RS03970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXW81_RS03990	COG4974	Belongs to the 'phage' integrase family
NXW81_RS04005	COG0606	chelatase, subunit chli
NXW81_RS04010	COG2205	protein histidine kinase activity
NXW81_RS04020	COG0702	epimerase
NXW81_RS04025	COG4771	TonB-dependent receptor
NXW81_RS04035	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW81_RS04040	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS04060	COG4771	TonB-dependent receptor
NXW81_RS04080	COG0745	RESPONSE REGULATOR receiver
NXW81_RS04080	COG3292	Two component regulator propeller
NXW81_RS04080	COG2205	protein histidine kinase activity
NXW81_RS04095	COG0673	inositol 2-dehydrogenase activity
NXW81_RS04115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW81_RS04115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW81_RS04130	COG3475	LICD family
NXW81_RS04145	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS04175	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXW81_RS04180	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW81_RS04185	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW81_RS04205	COG0561	phosphatase activity
NXW81_RS04275	COG4771	TonB-dependent receptor
NXW81_RS04280	COG0702	epimerase
NXW81_RS04290	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXW81_RS04300	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXW81_RS04310	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW81_RS04315	COG2211	Major facilitator Superfamily
NXW81_RS04320	COG3408	Glycogen debranching enzyme
NXW81_RS04345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXW81_RS04350	COG0793	Belongs to the peptidase S41A family
NXW81_RS04375	COG0702	epimerase
NXW81_RS04380	COG1629	transport
NXW81_RS04380	COG4206	TonB-dependent receptor
NXW81_RS04385	COG0745	RESPONSE REGULATOR receiver
NXW81_RS04385	COG2205	protein histidine kinase activity
NXW81_RS04385	COG3292	Two component regulator propeller
NXW81_RS04405	COG1053	succinate dehydrogenase
NXW81_RS04410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXW81_RS04455	COG1609	Transcriptional regulator
NXW81_RS04455	COG2207	Transcriptional regulator
NXW81_RS04540	COG0758	DNA mediated transformation
NXW81_RS04550	COG0826	peptidase U32
NXW81_RS04555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXW81_RS04580	COG1629	transport
NXW81_RS04580	COG4206	TonB-dependent receptor
NXW81_RS04615	COG0557	exoribonuclease II activity
NXW81_RS04625	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS04645	COG0702	epimerase
NXW81_RS04650	COG1629	transport
NXW81_RS04650	COG4206	TonB-dependent receptor
NXW81_RS04660	COG5002	protein histidine kinase activity
NXW81_RS04670	COG1629	transport
NXW81_RS04670	COG4206	TonB-dependent receptor
NXW81_RS04685	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS04690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXW81_RS04720	COG0657	acetylesterase activity
NXW81_RS04735	COG2271	Major facilitator Superfamily
NXW81_RS04740	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS04760	COG0702	epimerase
NXW81_RS04765	COG1629	transport
NXW81_RS04770	COG2186	Transcriptional regulator
NXW81_RS04790	COG0702	epimerase
NXW81_RS04795	COG4771	TonB-dependent receptor
NXW81_RS04840	COG0745	RESPONSE REGULATOR receiver
NXW81_RS04840	COG2205	protein histidine kinase activity
NXW81_RS04840	COG3292	Two component regulator propeller
NXW81_RS04890	COG1629	transport
NXW81_RS04890	COG4206	TonB-dependent receptor
NXW81_RS04900	COG4206	TonB-dependent receptor
NXW81_RS04900	COG1629	transport
NXW81_RS04925	COG3119	arylsulfatase activity
NXW81_RS04935	COG2814	Major facilitator Superfamily
NXW81_RS04950	COG4206	TonB-dependent receptor
NXW81_RS04950	COG1629	transport
NXW81_RS04970	COG0012	GTP binding
NXW81_RS04975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXW81_RS04980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXW81_RS04985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXW81_RS05025	COG4771	TonB-dependent receptor
NXW81_RS05030	COG3537	Alpha-1,2-mannosidase
NXW81_RS05040	COG1785	Belongs to the alkaline phosphatase family
NXW81_RS05050	COG0697	spore germination
NXW81_RS05065	COG3250	beta-galactosidase activity
NXW81_RS05070	COG0495	leucyl-tRNA aminoacylation
NXW81_RS05075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXW81_RS05080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXW81_RS05085	COG1360	Flagellar Motor Protein
NXW81_RS05090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXW81_RS05120	COG4206	TonB-dependent receptor
NXW81_RS05120	COG1629	transport
NXW81_RS05150	COG0731	radical SAM domain protein
NXW81_RS05150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXW81_RS05165	COG2205	protein histidine kinase activity
NXW81_RS05165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW81_RS05165	COG2198	Histidine kinase
NXW81_RS05165	COG0784	Response regulator, receiver
NXW81_RS05175	COG1629	transport
NXW81_RS05195	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS05280	COG4206	TonB-dependent receptor
NXW81_RS05280	COG1629	transport
NXW81_RS05295	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS05300	COG0659	secondary active sulfate transmembrane transporter activity
NXW81_RS05305	COG1592	Rubrerythrin
NXW81_RS05325	COG3292	Two component regulator propeller
NXW81_RS05325	COG0745	RESPONSE REGULATOR receiver
NXW81_RS05325	COG2205	protein histidine kinase activity
NXW81_RS05335	COG4771	TonB-dependent receptor
NXW81_RS05350	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW81_RS05365	COG4974	Belongs to the 'phage' integrase family
NXW81_RS05400	COG0551	DNA topoisomerase type I activity
NXW81_RS05400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW81_RS05420	COG2198	Histidine kinase
NXW81_RS05420	COG2205	protein histidine kinase activity
NXW81_RS05420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW81_RS05420	COG0784	Response regulator, receiver
NXW81_RS05555	COG0358	DNA primase activity
NXW81_RS05645	COG2027	D-alanyl-D-alanine carboxypeptidase
NXW81_RS05650	COG0427	acetyl-CoA hydrolase
NXW81_RS05660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW81_RS05685	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS05735	COG2177	Part of the ABC transporter FtsEX involved in
NXW81_RS05745	COG1968	undecaprenyl-diphosphatase activity
NXW81_RS05750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXW81_RS05755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXW81_RS05760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXW81_RS05800	COG0594	ribonuclease P activity
NXW81_RS05805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXW81_RS05815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXW81_RS05825	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXW81_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS05865	COG0726	polysaccharide deacetylase
NXW81_RS05875	COG1121	(ABC) transporter
NXW81_RS05885	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NXW81_RS05885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXW81_RS05890	COG1238	metal cluster binding
NXW81_RS05905	COG0823	Involved in the tonB-independent uptake of proteins
NXW81_RS05905	COG1506	peptidase
NXW81_RS05915	COG0116	Belongs to the methyltransferase superfamily
NXW81_RS05915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXW81_RS05920	COG1045	serine acetyltransferase
NXW81_RS05930	COG3279	Response regulator of the LytR AlgR family
NXW81_RS05940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXW81_RS05940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NXW81_RS05945	COG0142	geranyltranstransferase activity
NXW81_RS05955	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXW81_RS05960	COG1694	Mazg nucleotide pyrophosphohydrolase
NXW81_RS05965	COG1490	D-aminoacyl-tRNA deacylase activity
NXW81_RS05970	COG0322	excinuclease ABC activity
NXW81_RS05975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXW81_RS05980	COG0445	tRNA wobble uridine modification
NXW81_RS05995	COG4771	TonB-dependent receptor
NXW81_RS06035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXW81_RS06040	COG2715	membrane protein required for spore maturation
NXW81_RS06045	COG2255	four-way junction helicase activity
NXW81_RS06065	COG3591	Belongs to the peptidase S1B family
NXW81_RS06075	COG0513	Belongs to the DEAD box helicase family
NXW81_RS06100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXW81_RS06115	COG0612	Peptidase, M16
NXW81_RS06125	COG0584	glycerophosphoryl diester phosphodiesterase
NXW81_RS06145	COG0702	epimerase
NXW81_RS06150	COG1629	transport
NXW81_RS06160	COG1595	DNA-templated transcription, initiation
NXW81_RS06175	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NXW81_RS06185	COG4771	TonB-dependent receptor
NXW81_RS06190	COG0702	epimerase
NXW81_RS06205	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS06245	COG0681	Belongs to the peptidase S26 family
NXW81_RS06255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXW81_RS06285	COG1215	transferase activity, transferring glycosyl groups
NXW81_RS06315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXW81_RS06330	COG0702	epimerase
NXW81_RS06335	COG4771	TonB-dependent receptor
NXW81_RS06340	COG3119	arylsulfatase activity
NXW81_RS06345	COG0745	RESPONSE REGULATOR receiver
NXW81_RS06345	COG3292	Two component regulator propeller
NXW81_RS06345	COG3292	Two component regulator propeller
NXW81_RS06345	COG0745	RESPONSE REGULATOR receiver
NXW81_RS06345	COG2205	protein histidine kinase activity
NXW81_RS06345	COG2205	protein histidine kinase activity
NXW81_RS06360	COG0702	epimerase
NXW81_RS06365	COG4206	TonB-dependent receptor
NXW81_RS06365	COG1629	transport
NXW81_RS06395	COG0738	Major facilitator superfamily
NXW81_RS06410	COG1940	carbohydrate kinase activity
NXW81_RS06415	COG3250	beta-galactosidase activity
NXW81_RS06425	COG1609	Transcriptional regulator
NXW81_RS06435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW81_RS06440	COG1538	Outer membrane efflux protein
NXW81_RS06450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW81_RS06455	COG3250	beta-galactosidase activity
NXW81_RS06510	COG1629	transport
NXW81_RS06515	COG0702	epimerase
NXW81_RS06520	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS06525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NXW81_RS06535	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS06540	COG3119	arylsulfatase activity
NXW81_RS06545	COG5492	domain, Protein
NXW81_RS06555	COG0215	cysteine-tRNA ligase activity
NXW81_RS06560	COG0561	phosphatase activity
NXW81_RS06575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXW81_RS06580	COG0482	sulfurtransferase activity
NXW81_RS06595	COG0205	6-phosphofructokinase activity
NXW81_RS06600	COG0571	ribonuclease III activity
NXW81_RS06605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW81_RS06610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW81_RS06615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NXW81_RS06620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXW81_RS06655	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS06660	COG3475	LICD family
NXW81_RS06665	COG4750	Nucleotidyl transferase
NXW81_RS06680	COG1216	Glycosyl transferase, family 2
NXW81_RS06710	COG1216	Glycosyl transferase, family 2
NXW81_RS06780	COG1132	(ABC) transporter
NXW81_RS06790	COG0463	Glycosyl transferase, family 2
NXW81_RS06800	COG1368	sulfuric ester hydrolase activity
NXW81_RS06810	COG3341	Caulimovirus viroplasmin
NXW81_RS06810	COG0328	RNA-DNA hybrid ribonuclease activity
NXW81_RS06820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXW81_RS06830	COG0326	Molecular chaperone. Has ATPase activity
NXW81_RS06840	COG1166	arginine decarboxylase activity
NXW81_RS06845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NXW81_RS06850	COG1595	DNA-templated transcription, initiation
NXW81_RS06875	COG0779	Required for maturation of 30S ribosomal subunits
NXW81_RS06880	COG0195	Participates in both transcription termination and antitermination
NXW81_RS06885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXW81_RS06895	COG0719	Fe-S assembly protein
NXW81_RS06900	COG0396	ATPase activity
NXW81_RS06905	COG0719	Fe-S assembly protein
NXW81_RS06910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXW81_RS06915	COG0393	Putative heavy-metal-binding
NXW81_RS06930	COG2205	protein histidine kinase activity
NXW81_RS06930	COG2205	protein histidine kinase activity
NXW81_RS06930	COG3292	Two component regulator propeller
NXW81_RS06930	COG0745	RESPONSE REGULATOR receiver
NXW81_RS06930	COG3292	Two component regulator propeller
NXW81_RS06930	COG0745	RESPONSE REGULATOR receiver
NXW81_RS06935	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXW81_RS06940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXW81_RS06955	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXW81_RS06970	COG0187	DNA topoisomerase II activity
NXW81_RS06975	COG0268	Binds directly to 16S ribosomal RNA
NXW81_RS06985	COG1381	Involved in DNA repair and RecF pathway recombination
NXW81_RS07045	COG1610	YqeY-like protein
NXW81_RS07050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXW81_RS07065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXW81_RS07070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXW81_RS07075	COG0772	Belongs to the SEDS family
NXW81_RS07080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXW81_RS07085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXW81_RS07090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXW81_RS07105	COG0275	rRNA processing
NXW81_RS07110	COG2001	Belongs to the MraZ family
NXW81_RS07115	COG1595	DNA-templated transcription, initiation
NXW81_RS07130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXW81_RS07135	COG3292	Two component regulator propeller
NXW81_RS07135	COG2205	protein histidine kinase activity
NXW81_RS07135	COG0745	RESPONSE REGULATOR receiver
NXW81_RS07135	COG3292	Two component regulator propeller
NXW81_RS07135	COG2205	protein histidine kinase activity
NXW81_RS07135	COG0745	RESPONSE REGULATOR receiver
NXW81_RS07140	COG3940	Belongs to the glycosyl hydrolase 43 family
NXW81_RS07150	COG4771	TonB-dependent receptor
NXW81_RS07180	COG0756	dUTP diphosphatase activity
NXW81_RS07195	COG4942	peptidase
NXW81_RS07200	COG0745	RESPONSE REGULATOR receiver
NXW81_RS07200	COG2205	protein histidine kinase activity
NXW81_RS07200	COG3292	Two component regulator propeller
NXW81_RS07230	COG4771	TonB-dependent receptor
NXW81_RS07235	COG0561	phosphatase activity
NXW81_RS07265	COG3537	Alpha-1,2-mannosidase
NXW81_RS07330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW81_RS07335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXW81_RS07340	COG1595	DNA-templated transcription, initiation
NXW81_RS07375	COG1022	Amp-dependent synthetase and ligase
NXW81_RS07400	COG2954	triphosphatase activity
NXW81_RS07475	COG0561	phosphatase activity
NXW81_RS07480	COG4771	TonB-dependent receptor
NXW81_RS07510	COG2271	Major facilitator Superfamily
NXW81_RS07520	COG1629	transport
NXW81_RS07555	COG1595	DNA-templated transcription, initiation
NXW81_RS07560	COG0673	inositol 2-dehydrogenase activity
NXW81_RS07565	COG0673	inositol 2-dehydrogenase activity
NXW81_RS07590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXW81_RS07600	COG1621	beta-fructofuranosidase activity
NXW81_RS07605	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS07620	COG4771	TonB-dependent receptor
NXW81_RS07635	COG1609	Transcriptional regulator
NXW81_RS07635	COG2207	Transcriptional regulator
NXW81_RS07645	COG0423	glycine-tRNA ligase activity
NXW81_RS07655	COG1609	Transcriptional regulator
NXW81_RS07670	COG0738	Major facilitator superfamily
NXW81_RS07675	COG1063	alcohol dehydrogenase
NXW81_RS07685	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS07690	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS07695	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW81_RS07705	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS07715	COG4771	TonB-dependent receptor
NXW81_RS07725	COG1629	transport
NXW81_RS07760	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS07765	COG2205	protein histidine kinase activity
NXW81_RS07765	COG0745	RESPONSE REGULATOR receiver
NXW81_RS07765	COG3292	Two component regulator propeller
NXW81_RS07780	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXW81_RS07790	COG2211	Major facilitator Superfamily
NXW81_RS07800	COG1215	transferase activity, transferring glycosyl groups
NXW81_RS07805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXW81_RS07860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXW81_RS07865	COG0589	response to stress
NXW81_RS07865	COG0475	glutathione-regulated potassium exporter activity
NXW81_RS07870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXW81_RS07875	COG1136	(ABC) transporter
NXW81_RS07885	COG0733	neurotransmitter:sodium symporter activity
NXW81_RS07895	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXW81_RS07900	COG5002	protein histidine kinase activity
NXW81_RS07900	COG0784	Response regulator, receiver
NXW81_RS07905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXW81_RS07910	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXW81_RS07930	COG1082	Xylose isomerase domain protein TIM barrel
NXW81_RS07975	COG1346	cytolysis
NXW81_RS07980	COG1380	Effector of murein hydrolase LrgA
NXW81_RS07985	COG0280	phosphate acetyltransferase
NXW81_RS07990	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXW81_RS08000	COG1349	DNA-binding transcription factor activity
NXW81_RS08005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NXW81_RS08015	COG0371	Dehydrogenase
NXW81_RS08020	COG2271	Major facilitator Superfamily
NXW81_RS08025	COG0546	phosphoglycolate phosphatase activity
NXW81_RS08045	COG4372	Transposase
NXW81_RS08055	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS08085	COG1629	transport
NXW81_RS08110	COG0463	Glycosyl transferase, family 2
NXW81_RS08110	COG1216	Glycosyl transferase, family 2
NXW81_RS08115	COG2003	Belongs to the UPF0758 family
NXW81_RS08145	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW81_RS08150	COG4206	TonB-dependent receptor
NXW81_RS08150	COG1629	transport
NXW81_RS08155	COG1082	Xylose isomerase domain protein TIM barrel
NXW81_RS08160	COG0366	Alpha amylase catalytic
NXW81_RS08170	COG1785	Belongs to the alkaline phosphatase family
NXW81_RS08175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXW81_RS08180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXW81_RS08185	COG0515	serine threonine protein kinase
NXW81_RS08185	COG2815	serine threonine protein kinase
NXW81_RS08190	COG0564	pseudouridine synthase activity
NXW81_RS08215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXW81_RS08220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXW81_RS08225	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NXW81_RS08230	COG0436	Aminotransferase
NXW81_RS08240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXW81_RS08255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXW81_RS08260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXW81_RS08270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW81_RS08270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW81_RS08275	COG2890	protein-(glutamine-N5) methyltransferase activity
NXW81_RS08285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXW81_RS08295	COG0165	Argininosuccinate lyase
NXW81_RS08320	COG4206	TonB-dependent receptor
NXW81_RS08320	COG1629	transport
NXW81_RS08350	COG4771	TonB-dependent receptor
NXW81_RS08395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXW81_RS08400	COG1396	sequence-specific DNA binding
NXW81_RS08400	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS08410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXW81_RS08420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXW81_RS08425	COG0137	argininosuccinate synthase activity
NXW81_RS08435	COG1438	arginine binding
NXW81_RS08440	COG1070	Carbohydrate kinase
NXW81_RS08445	COG4806	L-rhamnose isomerase
NXW81_RS08455	COG0235	Class ii aldolase
NXW81_RS08460	COG1454	alcohol dehydrogenase
NXW81_RS08470	COG3292	Two component regulator propeller
NXW81_RS08470	COG0745	RESPONSE REGULATOR receiver
NXW81_RS08470	COG2205	protein histidine kinase activity
NXW81_RS08475	COG4771	TonB-dependent receptor
NXW81_RS08480	COG0702	epimerase
NXW81_RS08510	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW81_RS08515	COG3250	beta-galactosidase activity
NXW81_RS08590	COG0582	viral genome integration into host DNA
NXW81_RS08625	COG0564	pseudouridine synthase activity
NXW81_RS08655	COG3537	Alpha-1,2-mannosidase
NXW81_RS08660	COG3292	Two component regulator propeller
NXW81_RS08660	COG2205	protein histidine kinase activity
NXW81_RS08660	COG0745	RESPONSE REGULATOR receiver
NXW81_RS08680	COG4771	TonB-dependent receptor
NXW81_RS08705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXW81_RS08705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXW81_RS08710	COG0612	Peptidase, M16
NXW81_RS08715	COG0534	Mate efflux family protein
NXW81_RS08720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW81_RS08720	COG2205	protein histidine kinase activity
NXW81_RS08725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW81_RS08745	COG0488	(ABC) transporter
NXW81_RS08750	COG3590	peptidase
NXW81_RS08755	COG0138	bifunctional purine biosynthesis protein purh
NXW81_RS08780	COG0772	Belongs to the SEDS family
NXW81_RS08790	COG1774	PSP1 C-terminal conserved region
NXW81_RS08795	COG0470	DNA polymerase III
NXW81_RS08800	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXW81_RS08805	COG2193	ferroxidase activity
NXW81_RS08860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXW81_RS08865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXW81_RS08870	COG1160	GTP binding
NXW81_RS08880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXW81_RS08890	COG0724	RNA recognition motif
NXW81_RS08895	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXW81_RS08900	COG0740	serine-type endopeptidase activity
NXW81_RS08905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXW81_RS08910	COG0514	ATP-dependent DNA helicase (RecQ)
NXW81_RS08915	COG0517	IMP dehydrogenase activity
NXW81_RS08915	COG0516	GMP reductase activity
NXW81_RS08930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXW81_RS08945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXW81_RS08985	COG3022	response to hydroperoxide
NXW81_RS08990	COG0110	maltose O-acetyltransferase activity
NXW81_RS09010	COG1187	pseudouridine synthase activity
NXW81_RS09015	COG0017	Asparaginyl-tRNA synthetase
NXW81_RS09025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS09030	COG0745	RESPONSE REGULATOR receiver
NXW81_RS09030	COG2205	protein histidine kinase activity
NXW81_RS09030	COG3292	Two component regulator propeller
NXW81_RS09035	COG4372	Transposase
NXW81_RS09060	COG4372	Transposase
NXW81_RS09110	COG0702	epimerase
NXW81_RS09115	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXW81_RS09120	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXW81_RS09125	COG0052	Belongs to the universal ribosomal protein uS2 family
NXW81_RS09130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXW81_RS09145	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXW81_RS09150	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXW81_RS09155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXW81_RS09170	COG0482	sulfurtransferase activity
NXW81_RS09180	COG1570	exodeoxyribonuclease VII activity
NXW81_RS09190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXW81_RS09200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXW81_RS09205	COG0489	protein tyrosine kinase activity
NXW81_RS09210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW81_RS09250	COG0039	L-malate dehydrogenase activity
NXW81_RS09260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NXW81_RS09265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXW81_RS09270	COG0811	peptide transport
NXW81_RS09275	COG0848	biopolymer transport protein
NXW81_RS09290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXW81_RS09295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXW81_RS09300	COG0105	UTP biosynthetic process
NXW81_RS09305	COG0739	heme binding
NXW81_RS09320	COG0149	triose-phosphate isomerase activity
NXW81_RS09330	COG0302	gtp cyclohydrolase
NXW81_RS09335	COG0358	DNA primase activity
NXW81_RS09345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXW81_RS09365	COG0514	ATP-dependent DNA helicase (RecQ)
NXW81_RS09370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NXW81_RS09370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NXW81_RS09385	COG1629	transport
NXW81_RS09445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXW81_RS09460	COG0726	polysaccharide deacetylase
NXW81_RS09470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW81_RS09475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW81_RS09480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW81_RS09490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXW81_RS09505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXW81_RS09510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXW81_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS09530	COG0009	L-threonylcarbamoyladenylate synthase
NXW81_RS09540	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXW81_RS09545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXW81_RS09550	COG0658	competence protein
NXW81_RS09550	COG2333	competence protein COMEC
NXW81_RS09555	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXW81_RS09565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXW81_RS09580	COG4771	TonB-dependent receptor
NXW81_RS09590	COG3537	Alpha-1,2-mannosidase
NXW81_RS09595	COG3537	Alpha-1,2-mannosidase
NXW81_RS09605	COG3537	Alpha-1,2-mannosidase
NXW81_RS09610	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS09615	COG3279	Response regulator of the LytR AlgR family
NXW81_RS09620	COG3275	phosphorelay sensor kinase activity
NXW81_RS09635	COG0386	Belongs to the glutathione peroxidase family
NXW81_RS09645	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXW81_RS09660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXW81_RS09675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXW81_RS09680	COG0742	ribosomal rna small subunit methyltransferase
NXW81_RS09695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW81_RS09725	COG4206	TonB-dependent receptor
NXW81_RS09725	COG1629	transport
NXW81_RS09760	COG3537	Alpha-1,2-mannosidase
NXW81_RS09765	COG3537	Alpha-1,2-mannosidase
NXW81_RS09785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXW81_RS09790	COG0739	heme binding
NXW81_RS09800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXW81_RS09805	COG0741	lytic transglycosylase activity
NXW81_RS09805	COG1388	LysM domain
NXW81_RS09815	COG1475	DNA binding
NXW81_RS09820	COG1192	Involved in chromosome partitioning
NXW81_RS09825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXW81_RS09830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW81_RS09840	COG4589	Belongs to the CDS family
NXW81_RS09845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXW81_RS09860	COG1196	nuclear chromosome segregation
NXW81_RS09865	COG2239	Acts as a magnesium transporter
NXW81_RS09870	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXW81_RS09880	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW81_RS09920	COG0668	transmembrane transport
NXW81_RS09925	COG2207	Transcriptional regulator
NXW81_RS09925	COG0662	Cupin 2, conserved barrel domain protein
NXW81_RS09955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW81_RS09960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXW81_RS09965	COG0713	ATP synthesis coupled electron transport
NXW81_RS09980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXW81_RS09985	COG0649	NAD binding
NXW81_RS09985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW81_RS09990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW81_RS09995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXW81_RS10030	COG3250	beta-galactosidase activity
NXW81_RS10040	COG3250	beta-galactosidase activity
NXW81_RS10045	COG3940	Belongs to the glycosyl hydrolase 43 family
NXW81_RS10055	COG0702	epimerase
NXW81_RS10070	COG4771	TonB-dependent receptor
NXW81_RS10075	COG0702	epimerase
NXW81_RS10080	COG1629	transport
NXW81_RS10080	COG4206	TonB-dependent receptor
NXW81_RS10100	COG3537	Alpha-1,2-mannosidase
NXW81_RS10115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXW81_RS10120	COG0569	domain protein
NXW81_RS10125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXW81_RS10135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXW81_RS10140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXW81_RS10145	COG0805	protein transport
NXW81_RS10160	COG2271	Major facilitator Superfamily
NXW81_RS10165	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXW81_RS10170	COG3775	system Galactitol-specific IIC component
NXW81_RS10175	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS10185	COG2755	lipolytic protein G-D-S-L family
NXW81_RS10195	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10195	COG2205	protein histidine kinase activity
NXW81_RS10195	COG3292	Two component regulator propeller
NXW81_RS10205	COG0702	epimerase
NXW81_RS10210	COG4771	TonB-dependent receptor
NXW81_RS10230	COG3279	Response regulator of the LytR AlgR family
NXW81_RS10245	COG1242	4 iron, 4 sulfur cluster binding
NXW81_RS10255	COG0363	glucosamine-6-phosphate deaminase activity
NXW81_RS10260	COG0009	L-threonylcarbamoyladenylate synthase
NXW81_RS10270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW81_RS10275	COG0561	phosphatase activity
NXW81_RS10280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXW81_RS10305	COG2755	lipolytic protein G-D-S-L family
NXW81_RS10335	COG0702	epimerase
NXW81_RS10340	COG4771	TonB-dependent receptor
NXW81_RS10355	COG4771	TonB-dependent receptor
NXW81_RS10365	COG1629	transport
NXW81_RS10375	COG3401	FG-GAP repeat protein
NXW81_RS10390	COG2755	lipolytic protein G-D-S-L family
NXW81_RS10400	COG3401	FG-GAP repeat protein
NXW81_RS10410	COG3254	rhamnose metabolic process
NXW81_RS10415	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10415	COG3292	Two component regulator propeller
NXW81_RS10415	COG2205	protein histidine kinase activity
NXW81_RS10415	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10415	COG3292	Two component regulator propeller
NXW81_RS10415	COG2205	protein histidine kinase activity
NXW81_RS10435	COG3250	beta-galactosidase activity
NXW81_RS10440	COG3401	FG-GAP repeat protein
NXW81_RS10475	COG2205	protein histidine kinase activity
NXW81_RS10475	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10475	COG3292	Two component regulator propeller
NXW81_RS10500	COG4771	TonB-dependent receptor
NXW81_RS10525	COG3401	FG-GAP repeat protein
NXW81_RS10540	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS10560	COG4771	TonB-dependent receptor
NXW81_RS10565	COG0702	epimerase
NXW81_RS10580	COG4771	TonB-dependent receptor
NXW81_RS10680	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10680	COG3292	Two component regulator propeller
NXW81_RS10680	COG2205	protein histidine kinase activity
NXW81_RS10680	COG0745	RESPONSE REGULATOR receiver
NXW81_RS10680	COG2205	protein histidine kinase activity
NXW81_RS10680	COG3292	Two component regulator propeller
NXW81_RS10700	COG0546	phosphoglycolate phosphatase activity
NXW81_RS10730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXW81_RS10740	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXW81_RS10750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXW81_RS10755	COG0823	Involved in the tonB-independent uptake of proteins
NXW81_RS10755	COG1506	peptidase
NXW81_RS10775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXW81_RS10790	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXW81_RS10790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXW81_RS10795	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXW81_RS10800	COG1078	dGTPase activity
NXW81_RS10805	COG0284	orotidine-5'-phosphate decarboxylase activity
NXW81_RS10810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXW81_RS10815	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NXW81_RS10820	COG1704	LemA family
NXW81_RS10845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXW81_RS10850	COG2226	methyltransferase
NXW81_RS10855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXW81_RS10860	COG1702	phosphate starvation-inducible protein PhoH
NXW81_RS10885	COG2268	Band 7 protein
NXW81_RS10895	COG0101	tRNA pseudouridine synthase activity
NXW81_RS10915	COG3250	beta-galactosidase activity
NXW81_RS10920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXW81_RS10925	COG0673	inositol 2-dehydrogenase activity
NXW81_RS10970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXW81_RS10980	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXW81_RS10995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXW81_RS11000	COG0793	Belongs to the peptidase S41A family
NXW81_RS11005	COG2131	deaminase
NXW81_RS11015	COG0339	signal peptide processing
NXW81_RS11025	COG1970	mechanosensitive ion channel activity
NXW81_RS11030	COG0519	Catalyzes the synthesis of GMP from XMP
NXW81_RS11030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXW81_RS11055	COG1629	transport
NXW81_RS11060	COG0561	phosphatase activity
NXW81_RS11095	COG0297	glycogen (starch) synthase activity
NXW81_RS11110	COG0297	glycogen (starch) synthase activity
NXW81_RS11115	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXW81_RS11120	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXW81_RS11125	COG0543	2 iron, 2 sulfur cluster binding
NXW81_RS11130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXW81_RS11135	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXW81_RS11140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXW81_RS11155	COG0791	NLP P60 protein
NXW81_RS11170	COG0612	Peptidase, M16
NXW81_RS11175	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXW81_RS11180	COG1597	lipid kinase activity
NXW81_RS11185	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXW81_RS11200	COG1136	(ABC) transporter
NXW81_RS11220	COG2211	Major facilitator Superfamily
NXW81_RS11225	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXW81_RS11240	COG1674	ftsk spoiiie
NXW81_RS11250	COG0492	ferredoxin-NADP+ reductase activity
NXW81_RS11255	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS11295	COG4206	TonB-dependent receptor
NXW81_RS11295	COG1629	transport
NXW81_RS11350	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXW81_RS11350	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXW81_RS11360	COG1234	tRNA 3'-trailer cleavage
NXW81_RS11365	COG2989	Protein conserved in bacteria
NXW81_RS11385	COG3956	TIGRFAM MazG family protein
NXW81_RS11435	COG0525	valine-tRNA ligase activity
NXW81_RS11440	COG0784	Response regulator, receiver
NXW81_RS11440	COG2205	protein histidine kinase activity
NXW81_RS11455	COG4206	TonB-dependent receptor
NXW81_RS11455	COG1629	transport
NXW81_RS11460	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW81_RS11485	COG0653	protein targeting
NXW81_RS11490	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXW81_RS11500	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXW81_RS11520	COG1253	flavin adenine dinucleotide binding
NXW81_RS11525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXW81_RS11535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXW81_RS11545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXW81_RS11550	COG2204	response regulator
NXW81_RS11590	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXW81_RS11590	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXW81_RS11605	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXW81_RS11610	COG0563	adenylate kinase activity
NXW81_RS11615	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXW81_RS11620	COG1496	oxidoreductase activity
NXW81_RS11635	COG2706	6-phosphogluconolactonase activity
NXW81_RS11645	COG4804	nuclease activity
NXW81_RS11700	COG3142	Participates in the control of copper homeostasis
NXW81_RS11705	COG1418	mRNA catabolic process
NXW81_RS11755	COG4771	TonB-dependent receptor
NXW81_RS11760	COG0702	epimerase
NXW81_RS11790	COG0246	Mannitol dehydrogenase
NXW81_RS11800	COG1063	alcohol dehydrogenase
NXW81_RS11815	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXW81_RS11820	COG2832	Protein of unknown function (DUF454)
NXW81_RS11830	COG0602	queuosine metabolic process
NXW81_RS11835	COG0247	lactate metabolic process
NXW81_RS11840	COG1139	Iron-sulfur cluster binding protein
NXW81_RS11850	COG0351	phosphomethylpyrimidine kinase
NXW81_RS11875	COG4589	Belongs to the CDS family
NXW81_RS11885	COG2304	oxidoreductase activity
NXW81_RS11975	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NXW81_RS12135	COG1393	Belongs to the ArsC family
NXW81_RS12145	COG4771	TonB-dependent receptor
NXW81_RS12160	COG2233	PERMEase
NXW81_RS12165	COG1509	lysine 2,3-aminomutase activity
NXW81_RS12175	COG1115	amino acid carrier protein
NXW81_RS12240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXW81_RS12245	COG1120	ATPase activity
NXW81_RS12270	COG1192	Involved in chromosome partitioning
NXW81_RS12280	COG1629	transport
NXW81_RS12345	COG4974	Belongs to the 'phage' integrase family
NXW81_RS12350	COG4974	Belongs to the 'phage' integrase family
NXW81_RS12365	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS12375	COG0776	regulation of translation
NXW81_RS12405	COG1285	pathogenesis
NXW81_RS12415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXW81_RS12420	COG1388	LysM domain
NXW81_RS12420	COG0741	lytic transglycosylase activity
NXW81_RS12455	COG0534	Mate efflux family protein
NXW81_RS12465	COG0564	pseudouridine synthase activity
NXW81_RS12495	COG0346	lactoylglutathione lyase activity
NXW81_RS12545	COG1396	sequence-specific DNA binding
NXW81_RS12555	COG4268	DNA restriction-modification system
NXW81_RS12560	COG1401	restriction endodeoxyribonuclease activity
NXW81_RS12580	COG1063	alcohol dehydrogenase
NXW81_RS12620	COG0629	single-stranded DNA binding
NXW81_RS12730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXW81_RS12825	COG0739	heme binding
NXW81_RS12825	COG0741	lytic transglycosylase activity
NXW81_RS12825	COG1196	nuclear chromosome segregation
NXW81_RS12840	COG0556	nucleotide-excision repair
NXW81_RS12930	COG4974	Belongs to the 'phage' integrase family
NXW81_RS13095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NXW81_RS13100	COG4974	Belongs to the 'phage' integrase family
NXW81_RS13160	COG4974	Belongs to the 'phage' integrase family
NXW81_RS13190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NXW81_RS13205	COG3645	SOS response
NXW81_RS13230	COG0582	viral genome integration into host DNA
NXW81_RS13270	COG4974	Belongs to the 'phage' integrase family
NXW81_RS13280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXW81_RS13285	COG0784	Response regulator, receiver
NXW81_RS13285	COG2205	protein histidine kinase activity
NXW81_RS13290	COG0702	epimerase
NXW81_RS13300	COG4864	UPF0365 protein
NXW81_RS13315	COG0037	tRNA processing
NXW81_RS13325	COG1477	protein flavinylation
NXW81_RS13330	COG1971	Probably functions as a manganese efflux pump
NXW81_RS13345	COG0463	Glycosyl transferase, family 2
NXW81_RS13365	COG0148	phosphopyruvate hydratase activity
NXW81_RS13375	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXW81_RS13380	COG1082	Xylose isomerase domain protein TIM barrel
NXW81_RS13385	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXW81_RS13390	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW81_RS13395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NXW81_RS13400	COG4651	solute:proton antiporter activity
NXW81_RS13400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW81_RS13410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXW81_RS13415	COG0193	aminoacyl-tRNA hydrolase activity
NXW81_RS13420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXW81_RS13430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXW81_RS13445	COG0237	dephospho-CoA kinase activity
NXW81_RS13460	COG0542	response to heat
NXW81_RS13475	COG0583	DNA-binding transcription factor activity
NXW81_RS13505	COG3304	Inner membrane component domain
NXW81_RS13510	COG2855	membrane
NXW81_RS13515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXW81_RS13520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXW81_RS13540	COG0443	Heat shock 70 kDa protein
NXW81_RS13545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW81_RS13545	COG4651	solute:proton antiporter activity
NXW81_RS13550	COG0306	phosphate transporter
NXW81_RS13560	COG0586	Pfam SNARE associated Golgi protein
NXW81_RS13620	COG0038	chloride channel
NXW81_RS13630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXW81_RS13645	COG1940	carbohydrate kinase activity
NXW81_RS13655	COG3119	arylsulfatase activity
NXW81_RS13665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS13670	COG0702	epimerase
NXW81_RS13675	COG4771	TonB-dependent receptor
NXW81_RS13685	COG5434	Belongs to the glycosyl hydrolase 28 family
NXW81_RS13695	COG0745	RESPONSE REGULATOR receiver
NXW81_RS13695	COG2205	protein histidine kinase activity
NXW81_RS13695	COG3292	Two component regulator propeller
NXW81_RS13700	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXW81_RS13705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXW81_RS13715	COG3250	beta-galactosidase activity
NXW81_RS13740	COG4771	TonB-dependent receptor
NXW81_RS13745	COG0702	epimerase
NXW81_RS13765	COG4974	Belongs to the 'phage' integrase family
NXW81_RS13795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXW81_RS13835	COG3754	Rhamnan synthesis protein F
NXW81_RS13860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXW81_RS13885	COG3344	reverse transcriptase
NXW81_RS13905	COG1760	l-serine dehydratase
NXW81_RS13910	COG0598	Magnesium transport protein CorA
NXW81_RS13915	COG1193	negative regulation of DNA recombination
NXW81_RS13925	COG4974	Belongs to the 'phage' integrase family
NXW81_RS14015	COG3344	reverse transcriptase
NXW81_RS14095	COG0551	DNA topoisomerase type I activity
NXW81_RS14095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW81_RS14100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW81_RS14100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXW81_RS14155	COG4974	Belongs to the 'phage' integrase family
NXW81_RS14170	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXW81_RS14180	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXW81_RS14185	COG0456	acetyltransferase
NXW81_RS14200	COG0561	phosphatase activity
NXW81_RS14205	COG1169	isochorismate synthase
NXW81_RS14210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXW81_RS14215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXW81_RS14220	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS14230	COG1191	sigma factor activity
NXW81_RS14245	COG4206	TonB-dependent receptor
NXW81_RS14245	COG1629	transport
NXW81_RS14265	COG0783	Belongs to the Dps family
NXW81_RS14270	COG0583	DNA-binding transcription factor activity
NXW81_RS14275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXW81_RS14305	COG1595	DNA-templated transcription, initiation
NXW81_RS14320	COG4771	TonB-dependent receptor
NXW81_RS14330	COG0584	glycerophosphoryl diester phosphodiesterase
NXW81_RS14335	COG0584	glycerophosphoryl diester phosphodiesterase
NXW81_RS14360	COG4771	TonB-dependent receptor
NXW81_RS14365	COG0702	epimerase
NXW81_RS14375	COG0584	glycerophosphoryl diester phosphodiesterase
NXW81_RS14380	COG2271	Major facilitator Superfamily
NXW81_RS14405	COG4680	protein conserved in bacteria
NXW81_RS14435	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS14445	COG1882	Formate acetyltransferase
NXW81_RS14455	COG0210	DNA helicase
NXW81_RS14495	COG4804	nuclease activity
NXW81_RS14505	COG4974	Belongs to the 'phage' integrase family
NXW81_RS14535	COG0210	DNA helicase
NXW81_RS14605	COG3344	reverse transcriptase
NXW81_RS14665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW81_RS14665	COG0551	DNA topoisomerase type I activity
NXW81_RS14740	COG4974	Belongs to the 'phage' integrase family
NXW81_RS14745	COG1309	transcriptional regulator
NXW81_RS14810	COG0745	RESPONSE REGULATOR receiver
NXW81_RS14810	COG2205	protein histidine kinase activity
NXW81_RS14810	COG3292	Two component regulator propeller
NXW81_RS14820	COG1595	DNA-templated transcription, initiation
NXW81_RS14825	COG1629	transport
NXW81_RS14830	COG0561	phosphatase activity
NXW81_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS14870	COG0662	Cupin 2, conserved barrel domain protein
NXW81_RS14870	COG2207	Transcriptional regulator
NXW81_RS14875	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS14935	COG2267	carboxylic ester hydrolase activity
NXW81_RS14950	COG1629	transport
NXW81_RS14950	COG4206	TonB-dependent receptor
NXW81_RS14960	COG5492	domain, Protein
NXW81_RS14960	COG4932	domain protein
NXW81_RS14975	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS14985	COG1253	flavin adenine dinucleotide binding
NXW81_RS14990	COG0501	Belongs to the peptidase M48B family
NXW81_RS15020	COG0482	sulfurtransferase activity
NXW81_RS15035	COG2197	response regulator
NXW81_RS15045	COG1757	Na H antiporter
NXW81_RS15055	COG2814	Major facilitator Superfamily
NXW81_RS15060	COG4953	penicillin-binding protein 1C
NXW81_RS15065	COG2373	Large extracellular alpha-helical protein
NXW81_RS15070	COG0545	Peptidyl-prolyl cis-trans isomerase
NXW81_RS15125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXW81_RS15130	COG0646	methionine synthase
NXW81_RS15130	COG1410	methionine synthase
NXW81_RS15135	COG0778	Nitroreductase
NXW81_RS15150	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXW81_RS15155	COG0572	uridine kinase
NXW81_RS15165	COG4232	protein-disulfide reductase activity
NXW81_RS15180	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS15190	COG3250	beta-galactosidase activity
NXW81_RS15205	COG4771	TonB-dependent receptor
NXW81_RS15235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXW81_RS15240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXW81_RS15245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXW81_RS15250	COG0131	Imidazoleglycerol-phosphate dehydratase
NXW81_RS15260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXW81_RS15260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXW81_RS15265	COG1629	transport
NXW81_RS15265	COG4206	TonB-dependent receptor
NXW81_RS15315	COG1592	Rubrerythrin
NXW81_RS15315	COG1773	rubredoxin
NXW81_RS15330	COG3118	belongs to the thioredoxin family
NXW81_RS15345	COG3591	Belongs to the peptidase S1B family
NXW81_RS15350	COG3591	Belongs to the peptidase S1B family
NXW81_RS15355	COG0641	radical SAM
NXW81_RS15380	COG0420	3'-5' exonuclease activity
NXW81_RS15400	COG1410	methionine synthase
NXW81_RS15400	COG0646	methionine synthase
NXW81_RS15410	COG0463	Glycosyl transferase, family 2
NXW81_RS15415	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NXW81_RS15420	COG1032	radical SAM domain protein
NXW81_RS15440	COG0363	glucosamine-6-phosphate deaminase activity
NXW81_RS15445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXW81_RS15465	COG4974	Belongs to the 'phage' integrase family
NXW81_RS15485	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXW81_RS15525	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXW81_RS15530	COG0022	dehydrogenase e1 component
NXW81_RS15540	COG2264	protein methyltransferase activity
NXW81_RS15560	COG0590	tRNA wobble adenosine to inosine editing
NXW81_RS15565	COG0673	inositol 2-dehydrogenase activity
NXW81_RS15570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXW81_RS15620	COG4771	TonB-dependent receptor
NXW81_RS15640	COG3537	Alpha-1,2-mannosidase
NXW81_RS15680	COG1501	Belongs to the glycosyl hydrolase 31 family
NXW81_RS15685	COG5012	cobalamin binding
NXW81_RS15700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NXW81_RS15705	COG0698	ribose 5-phosphate isomerase
NXW81_RS15725	COG1070	Carbohydrate kinase
NXW81_RS15730	COG2160	L-arabinose isomerase activity
NXW81_RS15740	COG2816	NAD+ diphosphatase activity
NXW81_RS15770	COG4771	TonB-dependent receptor
NXW81_RS15775	COG3292	Two component regulator propeller
NXW81_RS15775	COG2205	protein histidine kinase activity
NXW81_RS15775	COG0745	RESPONSE REGULATOR receiver
NXW81_RS15780	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS15790	COG3507	Belongs to the glycosyl hydrolase 43 family
NXW81_RS15795	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXW81_RS15810	COG1482	cell wall glycoprotein biosynthetic process
NXW81_RS15815	COG4974	Belongs to the 'phage' integrase family
NXW81_RS15880	COG1442	glycosyl transferase family 8
NXW81_RS15880	COG1216	Glycosyl transferase, family 2
NXW81_RS15935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NXW81_RS15945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NXW81_RS15955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXW81_RS15980	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS15985	COG0110	maltose O-acetyltransferase activity
NXW81_RS15995	COG0463	Glycosyl transferase, family 2
NXW81_RS16030	COG4221	oxidoreductase activity
NXW81_RS16040	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXW81_RS16045	COG0471	metal ion transport
NXW81_RS16045	COG3273	potassium ion transport
NXW81_RS16050	COG0529	Catalyzes the synthesis of activated sulfate
NXW81_RS16055	COG0175	sulfate reduction
NXW81_RS16060	COG2895	sulfate adenylyltransferase (ATP) activity
NXW81_RS16080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXW81_RS16085	COG0242	peptide deformylase activity
NXW81_RS16095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXW81_RS16100	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXW81_RS16105	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXW81_RS16110	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXW81_RS16120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXW81_RS16125	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXW81_RS16130	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NXW81_RS16130	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXW81_RS16130	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXW81_RS16130	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXW81_RS16140	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXW81_RS16150	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXW81_RS16165	COG1940	carbohydrate kinase activity
NXW81_RS16190	COG4771	TonB-dependent receptor
NXW81_RS16285	COG1629	transport
NXW81_RS16310	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS16315	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS16345	COG4804	nuclease activity
NXW81_RS16360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXW81_RS16360	COG0551	DNA topoisomerase type I activity
NXW81_RS16380	COG4974	Belongs to the 'phage' integrase family
NXW81_RS16520	COG3344	reverse transcriptase
NXW81_RS16685	COG4771	TonB-dependent receptor
NXW81_RS16690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW81_RS16695	COG4335	DNA alkylation repair
NXW81_RS16700	COG0484	heat shock protein binding
NXW81_RS16705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXW81_RS16710	COG0488	(ABC) transporter
NXW81_RS16740	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS16820	COG2183	response to ionizing radiation
NXW81_RS16825	COG2202	Pas domain
NXW81_RS16825	COG2205	protein histidine kinase activity
NXW81_RS16830	COG0737	Belongs to the 5'-nucleotidase family
NXW81_RS16860	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXW81_RS16875	COG2985	domain, Protein
NXW81_RS16875	COG0490	domain, Protein
NXW81_RS16880	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXW81_RS16895	COG1022	Amp-dependent synthetase and ligase
NXW81_RS16900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW81_RS16905	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXW81_RS16910	COG1301	dicarboxylic acid transport
NXW81_RS16915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXW81_RS16920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXW81_RS16925	COG0363	glucosamine-6-phosphate deaminase activity
NXW81_RS16940	COG3279	Response regulator of the LytR AlgR family
NXW81_RS16950	COG1136	(ABC) transporter
NXW81_RS16950	COG0577	efflux transmembrane transporter activity
NXW81_RS16955	COG1136	(ABC) transporter
NXW81_RS16960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW81_RS16975	COG1271	oxidase subunit
NXW81_RS16985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXW81_RS16990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXW81_RS17015	COG0501	Belongs to the peptidase M48B family
NXW81_RS17020	COG1704	LemA family
NXW81_RS17030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXW81_RS17035	COG2885	chlorophyll binding
NXW81_RS17040	COG0534	Mate efflux family protein
NXW81_RS17045	COG2755	lipolytic protein G-D-S-L family
NXW81_RS17045	COG0657	acetylesterase activity
NXW81_RS17050	COG0784	Response regulator, receiver
NXW81_RS17050	COG2205	protein histidine kinase activity
NXW81_RS17070	COG0488	(ABC) transporter
NXW81_RS17075	COG4206	TonB-dependent receptor
NXW81_RS17075	COG1629	transport
NXW81_RS17085	COG2205	protein histidine kinase activity
NXW81_RS17085	COG0784	Response regulator, receiver
NXW81_RS17095	COG1368	sulfuric ester hydrolase activity
NXW81_RS17110	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS17120	COG2244	polysaccharide biosynthetic process
NXW81_RS17125	COG1216	Glycosyl transferase, family 2
NXW81_RS17125	COG1442	glycosyl transferase family 8
NXW81_RS17170	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS17185	COG1215	transferase activity, transferring glycosyl groups
NXW81_RS17220	COG1805	sodium ion transport
NXW81_RS17225	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXW81_RS17240	COG2871	sodium ion transport
NXW81_RS17250	COG0513	Belongs to the DEAD box helicase family
NXW81_RS17255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXW81_RS17270	COG1739	Uncharacterized protein family UPF0029
NXW81_RS17285	COG0778	Nitroreductase
NXW81_RS17295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXW81_RS17295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXW81_RS17300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXW81_RS17305	COG0357	Ribosomal RNA small subunit methyltransferase G
NXW81_RS17320	COG1408	metallophosphoesterase
NXW81_RS17340	COG2217	Heavy metal translocating P-type atpase
NXW81_RS17355	COG0321	lipoyl(octanoyl) transferase activity
NXW81_RS17365	COG0657	acetylesterase activity
NXW81_RS17365	COG2755	lipolytic protein G-D-S-L family
NXW81_RS17385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXW81_RS17395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXW81_RS17410	COG1678	Uncharacterized ACR, COG1678
NXW81_RS17425	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXW81_RS17450	COG3969	phosphoadenosine phosphosulfate
NXW81_RS17455	COG1475	DNA binding
NXW81_RS17515	COG0745	RESPONSE REGULATOR receiver
NXW81_RS17535	COG1074	ATP-dependent DNA helicase activity
NXW81_RS17575	COG1629	transport
NXW81_RS17575	COG4206	TonB-dependent receptor
NXW81_RS17585	COG1629	transport
NXW81_RS17585	COG4206	TonB-dependent receptor
NXW81_RS17620	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXW81_RS17625	COG3537	Alpha-1,2-mannosidase
NXW81_RS17640	COG1629	transport
NXW81_RS17640	COG4206	TonB-dependent receptor
NXW81_RS17670	COG3408	Glycogen debranching enzyme
NXW81_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS17710	COG3408	Glycogen debranching enzyme
NXW81_RS17720	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS17775	COG1629	transport
NXW81_RS17775	COG4206	TonB-dependent receptor
NXW81_RS17810	COG3392	D12 class N6 adenine-specific DNA methyltransferase
NXW81_RS17915	COG0740	serine-type endopeptidase activity
NXW81_RS18080	COG4232	protein-disulfide reductase activity
NXW81_RS18095	COG3420	alginic acid biosynthetic process
NXW81_RS18115	COG4206	TonB-dependent receptor
NXW81_RS18115	COG1629	transport
NXW81_RS18150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NXW81_RS18180	COG0784	Response regulator, receiver
NXW81_RS18180	COG2205	protein histidine kinase activity
NXW81_RS18185	COG3250	beta-galactosidase activity
NXW81_RS18190	COG3250	beta-galactosidase activity
NXW81_RS18195	COG0745	RESPONSE REGULATOR receiver
NXW81_RS18200	COG5002	protein histidine kinase activity
NXW81_RS18295	COG3250	beta-galactosidase activity
NXW81_RS18300	COG3292	Two component regulator propeller
NXW81_RS18300	COG0745	RESPONSE REGULATOR receiver
NXW81_RS18300	COG2205	protein histidine kinase activity
NXW81_RS18330	COG2966	Psort location CytoplasmicMembrane, score
NXW81_RS18345	COG0300	oxidoreductase activity
NXW81_RS18350	COG1011	Hydrolase
NXW81_RS18445	COG0442	prolyl-tRNA aminoacylation
NXW81_RS18450	COG0745	RESPONSE REGULATOR receiver
NXW81_RS18455	COG2205	protein histidine kinase activity
NXW81_RS18490	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXW81_RS18500	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXW81_RS18505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXW81_RS18515	COG0552	protein localization to endoplasmic reticulum
NXW81_RS18520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXW81_RS18535	COG0714	Associated with various cellular activities
NXW81_RS18550	COG2304	oxidoreductase activity
NXW81_RS18590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NXW81_RS18595	COG0542	response to heat
NXW81_RS18600	COG0326	Molecular chaperone. Has ATPase activity
NXW81_RS18605	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXW81_RS18650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXW81_RS18655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXW81_RS18660	COG0336	Belongs to the RNA methyltransferase TrmD family
NXW81_RS18670	COG0167	dihydroorotate dehydrogenase activity
NXW81_RS18675	COG0543	2 iron, 2 sulfur cluster binding
NXW81_RS18690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXW81_RS18705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW81_RS18710	COG1538	Outer membrane efflux protein
NXW81_RS18720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXW81_RS18725	COG1595	DNA-templated transcription, initiation
NXW81_RS18750	COG4988	ABC transporter
NXW81_RS18810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXW81_RS18815	COG1597	lipid kinase activity
NXW81_RS18820	COG0156	8-amino-7-oxononanoate synthase activity
NXW81_RS18835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXW81_RS18970	COG2433	Pfam Transposase IS66
NXW81_RS18975	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXW81_RS18980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXW81_RS19000	COG0560	Phosphoserine phosphatase
NXW81_RS19000	COG3830	Belongs to the UPF0237 family
NXW81_RS19005	COG0513	Belongs to the DEAD box helicase family
NXW81_RS19035	COG0246	Mannitol dehydrogenase
NXW81_RS19040	COG1609	Transcriptional regulator
NXW81_RS19045	COG1904	glucuronate isomerase
NXW81_RS19385	COG0484	heat shock protein binding
NXW81_RS19425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXW81_RS19430	COG0756	dUTP diphosphatase activity
NXW81_RS19495	COG4974	Belongs to the 'phage' integrase family
NXW81_RS19645	COG1475	DNA binding
NXW81_RS19665	COG1192	Involved in chromosome partitioning
NXW81_RS19670	COG0629	single-stranded DNA binding
NXW81_RS19725	COG0542	response to heat
NXW81_RS19790	COG3209	COG3209 Rhs family protein
NXW81_RS19900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXW81_RS19905	COG1196	nuclear chromosome segregation
NXW81_RS19905	COG0741	lytic transglycosylase activity
NXW81_RS19905	COG0739	heme binding
NXW81_RS19965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXW81_RS20220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NXW81_RS20220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NXW81_RS20275	COG0587	DNA-directed DNA polymerase activity
NXW81_RS20285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW81_RS20290	COG0587	DNA-directed DNA polymerase activity
NXW81_RS20365	COG4974	Belongs to the 'phage' integrase family
NXW81_RS20380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXW81_RS20420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXW81_RS20435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXW81_RS20445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXW81_RS20455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXW81_RS20455	COG3153	acetyltransferase
NXW81_RS20490	COG0477	Major facilitator Superfamily
NXW81_RS20490	COG2814	Major facilitator Superfamily
NXW81_RS20495	COG2115	Belongs to the xylose isomerase family
NXW81_RS20510	COG0351	phosphomethylpyrimidine kinase
NXW81_RS20515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXW81_RS20520	COG0045	succinate-CoA ligase (ADP-forming) activity
NXW81_RS20525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXW81_RS20545	COG3279	Response regulator of the LytR AlgR family
NXW81_RS20590	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXW81_RS20595	COG0348	domain, Protein
NXW81_RS20615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXW81_RS20620	COG2731	YhcH YjgK YiaL family protein
NXW81_RS20630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXW81_RS20805	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NXW81_RS20910	COG2205	protein histidine kinase activity
NXW81_RS20915	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXW81_RS20935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXW81_RS20945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NXW81_RS21005	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS21015	COG0110	maltose O-acetyltransferase activity
NXW81_RS21030	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXW81_RS21040	COG5039	Polysaccharide pyruvyl transferase
NXW81_RS21080	COG0540	Belongs to the ATCase OTCase family
NXW81_RS21085	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXW81_RS21100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXW81_RS21105	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXW81_RS21110	COG2985	domain, Protein
NXW81_RS21130	COG2207	Transcriptional regulator
NXW81_RS21130	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS21135	COG2207	Transcriptional regulator
NXW81_RS21145	COG1690	Belongs to the RtcB family
NXW81_RS21150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXW81_RS21150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW81_RS21160	COG2431	L-lysine efflux transmembrane transporter activity
NXW81_RS21165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXW81_RS21175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXW81_RS21180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXW81_RS21185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW81_RS21190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXW81_RS21195	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW81_RS21200	COG0356	it plays a direct role in the translocation of protons across the membrane
NXW81_RS21210	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXW81_RS21215	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXW81_RS21220	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXW81_RS21225	COG0454	-acetyltransferase
NXW81_RS21420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXW81_RS21430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXW81_RS21435	COG1011	Hydrolase
NXW81_RS21440	COG0534	Mate efflux family protein
NXW81_RS21450	COG0577	efflux transmembrane transporter activity
NXW81_RS21450	COG1136	(ABC) transporter
NXW81_RS21465	COG2204	response regulator
NXW81_RS21480	COG1151	hydroxylamine reductase activity
NXW81_RS21485	COG2233	PERMEase
NXW81_RS21495	COG1022	Amp-dependent synthetase and ligase
NXW81_RS21500	COG0745	RESPONSE REGULATOR receiver
NXW81_RS21505	COG5002	protein histidine kinase activity
NXW81_RS21525	COG3118	belongs to the thioredoxin family
NXW81_RS21600	COG5002	protein histidine kinase activity
NXW81_RS21610	COG0352	thiamine-phosphate diphosphorylase activity
NXW81_RS21615	COG2022	thiamine diphosphate biosynthetic process
NXW81_RS21620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXW81_RS21630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXW81_RS21635	COG0352	thiamine-phosphate diphosphorylase activity
NXW81_RS21655	COG0574	Belongs to the PEP-utilizing enzyme family
NXW81_RS21655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXW81_RS21660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXW81_RS21665	COG0564	pseudouridine synthase activity
NXW81_RS21685	COG0024	Methionine aminopeptidase
NXW81_RS21695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXW81_RS21705	COG0481	GTPase activity
NXW81_RS21730	COG0708	Exodeoxyribonuclease III
NXW81_RS21745	COG0217	transcriptional regulatory protein
NXW81_RS21750	COG0072	phenylalanine-tRNA ligase activity
NXW81_RS21750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXW81_RS21755	COG0305	Participates in initiation and elongation during chromosome replication
NXW81_RS21760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXW81_RS21765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXW81_RS21770	COG4657	Part of a membrane complex involved in electron transport
NXW81_RS21775	COG4660	Part of a membrane complex involved in electron transport
NXW81_RS21780	COG4659	FMN binding
NXW81_RS21785	COG4658	electron transport chain
NXW81_RS21790	COG4656	Part of a membrane complex involved in electron transport
NXW81_RS21860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW81_RS21870	COG0463	Glycosyl transferase, family 2
NXW81_RS21880	COG1216	Glycosyl transferase, family 2
NXW81_RS21900	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXW81_RS21930	COG1088	dTDP-glucose 4,6-dehydratase activity
NXW81_RS21950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXW81_RS21955	COG1086	Polysaccharide biosynthesis protein
NXW81_RS21975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXW81_RS22005	COG0504	CTP synthase activity
NXW81_RS22010	COG0706	membrane insertase activity
NXW81_RS22015	COG0534	Mate efflux family protein
NXW81_RS22020	COG1506	peptidase
NXW81_RS22020	COG0823	Involved in the tonB-independent uptake of proteins
NXW81_RS22035	COG1983	PspC domain protein
NXW81_RS22055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXW81_RS22065	COG1388	LysM domain
NXW81_RS22065	COG3942	CHAP domain
NXW81_RS22095	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXW81_RS22100	COG0556	nucleotide-excision repair
NXW81_RS22120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXW81_RS22130	COG0842	Transport permease protein
NXW81_RS22135	COG0842	Transport permease protein
NXW81_RS22140	COG1131	(ABC) transporter
NXW81_RS22145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW81_RS22155	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS22155	COG2207	Transcriptional regulator
NXW81_RS22170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXW81_RS22175	COG0505	Belongs to the CarA family
NXW81_RS22185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NXW81_RS22190	COG0067	glutamate synthase
NXW81_RS22190	COG0069	glutamate synthase activity
NXW81_RS22190	COG0070	glutamate synthase
NXW81_RS22200	COG0367	asparagine synthase
NXW81_RS22215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXW81_RS22220	COG0436	Aminotransferase
NXW81_RS22230	COG0347	Belongs to the P(II) protein family
NXW81_RS22235	COG0004	ammonium transporteR
NXW81_RS22275	COG0471	metal ion transport
NXW81_RS22275	COG0490	domain, Protein
NXW81_RS22280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW81_RS22280	COG2205	protein histidine kinase activity
NXW81_RS22285	COG1979	alcohol dehydrogenase
NXW81_RS22295	COG0133	tryptophan synthase activity
NXW81_RS22300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXW81_RS22310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXW81_RS22315	COG0134	indole-3-glycerol-phosphate synthase activity
NXW81_RS22320	COG0135	phosphoribosylanthranilate isomerase activity
NXW81_RS22325	COG0159	tryptophan synthase activity
NXW81_RS22330	COG0252	asparaginase activity
NXW81_RS22340	COG0745	RESPONSE REGULATOR receiver
NXW81_RS22345	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXW81_RS22370	COG0138	bifunctional purine biosynthesis protein purh
NXW81_RS22385	COG1730	sister chromatid segregation
NXW81_RS22390	COG3487	Iron-regulated protein
NXW81_RS22415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXW81_RS22415	COG1333	cytochrome c biogenesis protein
NXW81_RS22420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS22455	COG4771	TonB-dependent receptor
NXW81_RS22465	COG4771	TonB-dependent receptor
NXW81_RS22475	COG2985	domain, Protein
NXW81_RS22475	COG0490	domain, Protein
NXW81_RS22480	COG1230	cation diffusion facilitator family transporter
NXW81_RS22500	COG1609	Transcriptional regulator
NXW81_RS22505	COG2721	sulfolactate sulfo-lyase activity
NXW81_RS22520	COG4452	Inner membrane protein CreD
NXW81_RS22555	COG1733	regulation of RNA biosynthetic process
NXW81_RS22575	COG0228	four-way junction DNA binding
NXW81_RS22585	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXW81_RS22595	COG1070	Carbohydrate kinase
NXW81_RS22605	COG0738	Major facilitator superfamily
NXW81_RS22620	COG4771	TonB-dependent receptor
NXW81_RS22670	COG1177	transmembrane transport
NXW81_RS22675	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXW81_RS22680	COG3842	ATPase activity
NXW81_RS22685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXW81_RS22690	COG0058	SHG alpha-glucan phosphorylase activity
NXW81_RS22700	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXW81_RS22720	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXW81_RS22780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXW81_RS22785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXW81_RS22790	COG4948	Mandelate Racemase Muconate Lactonizing
NXW81_RS22805	COG1295	ribonuclease BN
NXW81_RS22810	COG0778	Nitroreductase
NXW81_RS22820	COG0704	Plays a role in the regulation of phosphate uptake
NXW81_RS22825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXW81_RS22830	COG0581	inorganic phosphate transmembrane transporter activity
NXW81_RS22835	COG0573	inorganic phosphate transmembrane transporter activity
NXW81_RS22845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXW81_RS22855	COG0586	Pfam SNARE associated Golgi protein
NXW81_RS22865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXW81_RS22880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXW81_RS22890	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXW81_RS22940	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS22950	COG0438	transferase activity, transferring glycosyl groups
NXW81_RS22970	COG1216	Glycosyl transferase, family 2
NXW81_RS22990	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NXW81_RS23000	COG1083	cytidylyl-transferase
NXW81_RS23035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXW81_RS23040	COG0497	DNA recombination
NXW81_RS23055	COG0592	DNA-directed DNA polymerase activity
NXW81_RS23070	COG0321	lipoyl(octanoyl) transferase activity
NXW81_RS23070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXW81_RS23075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXW81_RS23085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXW81_RS23090	COG0156	8-amino-7-oxononanoate synthase activity
NXW81_RS23100	COG5002	protein histidine kinase activity
NXW81_RS23110	COG0019	diaminopimelate decarboxylase activity
NXW81_RS23115	COG0527	aspartate kinase activity
NXW81_RS23120	COG2884	Cell division ATP-binding protein ftsE
NXW81_RS23125	COG0140	phosphoribosyl-ATP diphosphatase activity
NXW81_RS23125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXW81_RS23130	COG0107	imidazoleglycerol-phosphate synthase activity
NXW81_RS23135	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXW81_RS23140	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXW81_RS23145	COG0788	formyltetrahydrofolate deformylase activity
NXW81_RS23165	COG0667	Aldo Keto reductase
NXW81_RS23170	COG2249	NAD(P)H dehydrogenase (quinone) activity
NXW81_RS23205	COG0534	Mate efflux family protein
NXW81_RS23215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXW81_RS23230	COG4884	unkown
NXW81_RS23230	COG3831	ATPase activity
NXW81_RS23235	COG2885	chlorophyll binding
NXW81_RS23235	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXW81_RS23280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXW81_RS23295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXW81_RS23325	COG0655	NAD(P)H dehydrogenase (quinone) activity
NXW81_RS23340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXW81_RS23350	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXW81_RS23365	COG4771	TonB-dependent receptor
NXW81_RS23435	COG0681	Belongs to the peptidase S26 family
NXW81_RS23455	COG3831	ATPase activity
NXW81_RS23455	COG4884	unkown
NXW81_RS23470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NXW81_RS23475	COG1162	GTPase activity
NXW81_RS23505	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXW81_RS23510	COG5002	protein histidine kinase activity
NXW81_RS23520	COG1312	Catalyzes the dehydration of D-mannonate
NXW81_RS23525	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS23530	COG1609	Transcriptional regulator
NXW81_RS23545	COG2223	nitrite transmembrane transporter activity
NXW81_RS23555	COG4771	TonB-dependent receptor
NXW81_RS23565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXW81_RS23565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXW81_RS23580	COG2226	methyltransferase
NXW81_RS23615	COG0784	Response regulator, receiver
NXW81_RS23615	COG2205	protein histidine kinase activity
NXW81_RS23620	COG0511	ligase activity, forming carbon-carbon bonds
NXW81_RS23625	COG0439	Biotin carboxylase
NXW81_RS23630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW81_RS23640	COG1620	l-lactate permease
NXW81_RS23645	COG4974	Belongs to the 'phage' integrase family
NXW81_RS23720	COG0739	heme binding
NXW81_RS23775	COG2198	Histidine kinase
NXW81_RS23775	COG2205	protein histidine kinase activity
NXW81_RS23775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXW81_RS23775	COG0784	Response regulator, receiver
NXW81_RS23785	COG0010	Belongs to the arginase family
NXW81_RS23795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXW81_RS23795	COG4651	solute:proton antiporter activity
NXW81_RS23815	COG0588	phosphoglycerate mutase activity
NXW81_RS23820	COG1830	Aldolase
NXW81_RS23830	COG2095	MarC family integral membrane protein
NXW81_RS23860	COG0745	RESPONSE REGULATOR receiver
NXW81_RS23860	COG2205	protein histidine kinase activity
NXW81_RS23860	COG3292	Two component regulator propeller
NXW81_RS23865	COG1629	transport
NXW81_RS23870	COG0702	epimerase
NXW81_RS23910	COG0745	RESPONSE REGULATOR receiver
NXW81_RS23910	COG3292	Two component regulator propeller
NXW81_RS23910	COG2205	protein histidine kinase activity
NXW81_RS23910	COG0745	RESPONSE REGULATOR receiver
NXW81_RS23910	COG2205	protein histidine kinase activity
NXW81_RS23910	COG3292	Two component regulator propeller
NXW81_RS23930	COG2433	Pfam Transposase IS66
NXW81_RS23935	COG4372	Transposase
NXW81_RS24055	COG3015	lipoprotein NlpE involved in copper resistance
NXW81_RS24100	COG0428	transporter
NXW81_RS24110	COG2375	cellular response to nickel ion
NXW81_RS24110	COG1132	(ABC) transporter
NXW81_RS24135	COG4771	TonB-dependent receptor
NXW81_RS24160	COG0622	Phosphoesterase
NXW81_RS24310	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NXW81_RS24315	COG1690	Belongs to the RtcB family
NXW81_RS24325	COG3279	Response regulator of the LytR AlgR family
NXW81_RS24350	COG1472	Belongs to the glycosyl hydrolase 3 family
NXW81_RS24365	COG0702	epimerase
NXW81_RS24370	COG4771	TonB-dependent receptor
NXW81_RS24385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXW81_RS24405	COG0628	permease
NXW81_RS24410	COG1215	transferase activity, transferring glycosyl groups
NXW81_RS24415	COG0456	acetyltransferase
NXW81_RS24420	COG0189	ligase activity
NXW81_RS24420	COG0569	domain protein
NXW81_RS24425	COG0577	efflux transmembrane transporter activity
NXW81_RS24425	COG1136	(ABC) transporter
NXW81_RS24430	COG0436	Aminotransferase
NXW81_RS24445	COG0488	(ABC) transporter
NXW81_RS24460	COG0745	RESPONSE REGULATOR receiver
NXW81_RS24520	COG4206	TonB-dependent receptor
NXW81_RS24535	COG3033	Beta-eliminating lyase
NXW81_RS24560	COG0629	single-stranded DNA binding
NXW81_RS24565	COG1194	a g-specific adenine glycosylase
NXW81_RS24575	COG1530	ribonuclease E activity
NXW81_RS24625	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS24660	COG4771	TonB-dependent receptor
NXW81_RS24665	COG1979	alcohol dehydrogenase
NXW81_RS24680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXW81_RS24690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXW81_RS24705	COG4191	Histidine kinase
NXW81_RS24710	COG2204	response regulator
NXW81_RS24730	COG0577	efflux transmembrane transporter activity
NXW81_RS24740	COG1136	(ABC) transporter
NXW81_RS24750	COG1252	NADH dehydrogenase
NXW81_RS24755	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXW81_RS24760	COG0295	cytidine deaminase activity
NXW81_RS24770	COG3059	membrane
NXW81_RS24775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXW81_RS24780	COG0488	(ABC) transporter
NXW81_RS24815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXW81_RS24835	COG4206	TonB-dependent receptor
NXW81_RS24835	COG1629	transport
NXW81_RS24850	COG0686	Belongs to the AlaDH PNT family
NXW81_RS24900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXW81_RS24910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXW81_RS24915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXW81_RS24930	COG1595	DNA-templated transcription, initiation
NXW81_RS24945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXW81_RS24950	COG1741	Belongs to the pirin family
NXW81_RS24955	COG0259	pyridoxamine-phosphate oxidase activity
NXW81_RS24970	COG0346	lactoylglutathione lyase activity
NXW81_RS25025	COG1918	ferrous iron import across plasma membrane
NXW81_RS25025	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXW81_RS25030	COG0037	tRNA processing
NXW81_RS25045	COG3119	arylsulfatase activity
NXW81_RS25050	COG0534	Mate efflux family protein
NXW81_RS25055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXW81_RS25060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXW81_RS25100	COG0582	viral genome integration into host DNA
NXW81_RS25115	COG0768	penicillin binding
NXW81_RS25120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXW81_RS25195	COG2003	Belongs to the UPF0758 family
NXW81_RS25235	COG4372	Transposase
NXW81_RS25275	COG1983	PspC domain protein
NXW81_RS25280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXW81_RS25305	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXW81_RS25320	COG0668	transmembrane transport
NXW81_RS25330	COG3250	beta-galactosidase activity
NXW81_RS25335	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS25340	COG3119	arylsulfatase activity
NXW81_RS25355	COG4206	TonB-dependent receptor
NXW81_RS25355	COG1629	transport
NXW81_RS25375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXW81_RS25390	COG0348	domain, Protein
NXW81_RS25400	COG4977	sequence-specific DNA binding
NXW81_RS25400	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS25405	COG2205	protein histidine kinase activity
NXW81_RS25405	COG0745	RESPONSE REGULATOR receiver
NXW81_RS25405	COG3292	Two component regulator propeller
NXW81_RS25405	COG2205	protein histidine kinase activity
NXW81_RS25405	COG0745	RESPONSE REGULATOR receiver
NXW81_RS25405	COG3292	Two component regulator propeller
NXW81_RS25410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXW81_RS25415	COG1830	Aldolase
NXW81_RS25420	COG0588	phosphoglycerate mutase activity
NXW81_RS25435	COG4206	TonB-dependent receptor
NXW81_RS25435	COG1629	transport
NXW81_RS25465	COG1119	ATPase activity
NXW81_RS25470	COG3661	Belongs to the glycosyl hydrolase 67 family
NXW81_RS25485	COG2211	Major facilitator Superfamily
NXW81_RS25495	COG1523	belongs to the glycosyl hydrolase 13 family
NXW81_RS25500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXW81_RS25535	COG4372	Transposase
NXW81_RS25545	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXW81_RS25550	COG2814	Major facilitator Superfamily
NXW81_RS25555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXW81_RS25560	COG0126	phosphoglycerate kinase activity
NXW81_RS25575	COG2311	Membrane
NXW81_RS25585	COG0424	maF-like protein
NXW81_RS25605	COG0778	Nitroreductase
NXW81_RS25615	COG0288	reversible hydration of carbon dioxide
NXW81_RS25625	COG1629	transport
NXW81_RS25640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW81_RS25650	COG0511	ligase activity, forming carbon-carbon bonds
NXW81_RS25655	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXW81_RS25660	COG0191	fructose-bisphosphate aldolase activity
NXW81_RS25665	COG0254	rRNA binding
NXW81_RS25670	COG1373	ATPase (AAA superfamily
NXW81_RS25720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXW81_RS25745	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXW81_RS25750	COG0511	ligase activity, forming carbon-carbon bonds
NXW81_RS25770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXW81_RS25785	COG1280	lysine exporter protein (LysE YggA)
NXW81_RS25795	COG0745	RESPONSE REGULATOR receiver
NXW81_RS25795	COG3292	Two component regulator propeller
NXW81_RS25795	COG2205	protein histidine kinase activity
NXW81_RS25795	COG0745	RESPONSE REGULATOR receiver
NXW81_RS25795	COG3292	Two component regulator propeller
NXW81_RS25795	COG2205	protein histidine kinase activity
NXW81_RS25810	COG1649	PFAM Uncharacterised BCR, COG1649
NXW81_RS25830	COG1966	Carbon starvation protein
NXW81_RS25835	COG1649	PFAM Uncharacterised BCR, COG1649
NXW81_RS25840	COG4372	Transposase
NXW81_RS25885	COG2113	Glycine betaine
NXW81_RS25890	COG4176	ABC-type proline glycine betaine transport system permease component
NXW81_RS25900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXW81_RS25910	COG0745	RESPONSE REGULATOR receiver
NXW81_RS25910	COG2205	protein histidine kinase activity
NXW81_RS25910	COG3292	Two component regulator propeller
NXW81_RS25915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXW81_RS25915	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NXW81_RS25925	COG1621	beta-fructofuranosidase activity
NXW81_RS25940	COG0561	phosphatase activity
NXW81_RS25945	COG1629	transport
NXW81_RS25945	COG4206	TonB-dependent receptor
NXW81_RS25955	COG1621	beta-fructofuranosidase activity
NXW81_RS25965	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXW81_RS25970	COG0475	glutathione-regulated potassium exporter activity
NXW81_RS26030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXW81_RS26035	COG1960	acyl-CoA dehydrogenase activity
NXW81_RS26040	COG0705	Rhomboid family
NXW81_RS26055	COG1956	GAF domain-containing protein
NXW81_RS26065	COG0484	heat shock protein binding
NXW81_RS26070	COG2194	sulfuric ester hydrolase activity
NXW81_RS26090	COG0028	Belongs to the TPP enzyme family
NXW81_RS26120	COG0459	protein refolding
NXW81_RS26125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXW81_RS26155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXW81_RS26165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXW81_RS26180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXW81_RS26220	COG0124	histidyl-tRNA synthetase
NXW81_RS26235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXW81_RS26260	COG0514	ATP-dependent DNA helicase (RecQ)
NXW81_RS26270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXW81_RS26275	COG1368	sulfuric ester hydrolase activity
NXW81_RS26280	COG0671	phosphoesterase, PA-phosphatase related
NXW81_RS26285	COG0473	3-isopropylmalate dehydrogenase activity
NXW81_RS26295	COG0066	3-isopropylmalate dehydratase activity
NXW81_RS26300	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXW81_RS26305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXW81_RS26365	COG1917	Cupin 2, conserved barrel domain protein
NXW81_RS26365	COG4977	sequence-specific DNA binding
NXW81_RS26390	COG1028	Short-chain dehydrogenase reductase Sdr
NXW81_RS26400	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXW81_RS26405	COG3118	belongs to the thioredoxin family
NXW81_RS26415	COG0439	Biotin carboxylase
NXW81_RS26425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXW81_RS26435	COG2873	o-acetylhomoserine
NXW81_RS26440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NXW81_RS26485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NXW81_RS26495	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXW81_RS26500	COG1088	dTDP-glucose 4,6-dehydratase activity
NXW81_RS26505	COG1575	Belongs to the MenA family. Type 1 subfamily
NXW81_RS26510	COG1408	metallophosphoesterase
NXW81_RS26520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXW81_RS26525	COG0194	GDP metabolic process
NXW81_RS26545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXW81_RS26550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXW81_RS26560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXW81_RS26565	COG0750	zinc metalloprotease
NXW81_RS26570	COG2814	Major facilitator Superfamily
NXW81_RS26580	COG1328	CTP reductase activity
NXW81_RS26635	COG4206	TonB-dependent receptor
NXW81_RS26635	COG1629	transport
NXW81_RS26665	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXW81_RS26695	COG1538	Outer membrane efflux protein
NXW81_RS26745	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXW81_RS26760	COG0561	phosphatase activity
NXW81_RS26765	COG4771	TonB-dependent receptor
NXW81_RS26790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXW81_RS26855	COG1505	serine-type exopeptidase activity
NXW81_RS26870	COG3119	arylsulfatase activity
NXW81_RS26875	COG0617	tRNA 3'-terminal CCA addition
NXW81_RS26890	COG0632	four-way junction helicase activity
NXW81_RS26895	COG0673	inositol 2-dehydrogenase activity
NXW81_RS26900	COG1272	protein, Hemolysin III
NXW81_RS26905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXW81_RS26910	COG4206	TonB-dependent receptor
NXW81_RS26910	COG1629	transport
NXW81_RS26925	COG2204	response regulator
NXW81_RS26930	COG0488	(ABC) transporter
NXW81_RS26980	COG1595	DNA-templated transcription, initiation
NXW81_RS26995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXW81_RS27005	COG1522	sequence-specific DNA binding
NXW81_RS27035	COG0811	peptide transport
NXW81_RS27045	COG0084	hydrolase, TatD family'
NXW81_RS27065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXW81_RS27070	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXW81_RS27075	COG0205	6-phosphofructokinase activity
NXW81_RS27115	COG0372	Belongs to the citrate synthase family
NXW81_RS27125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXW81_RS27130	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXW81_RS27140	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXW81_RS27155	COG0028	Belongs to the TPP enzyme family
NXW81_RS27160	COG0129	dihydroxy-acid dehydratase activity
NXW81_RS27190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXW81_RS27255	COG1629	transport
NXW81_RS27255	COG4206	TonB-dependent receptor
NXW81_RS27265	COG1595	DNA-templated transcription, initiation
NXW81_RS27270	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW81_RS27270	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW81_RS27275	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXW81_RS27330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXW81_RS27345	COG3537	Alpha-1,2-mannosidase
NXW81_RS27365	COG0702	epimerase
NXW81_RS27370	COG4206	TonB-dependent receptor
NXW81_RS27370	COG1629	transport
NXW81_RS27375	COG1940	carbohydrate kinase activity
NXW81_RS27385	COG2188	Transcriptional regulator
NXW81_RS27435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXW81_RS27445	COG1609	Transcriptional regulator
NXW81_RS27445	COG2207	Transcriptional regulator
NXW81_RS27450	COG3292	Two component regulator propeller
NXW81_RS27450	COG2205	protein histidine kinase activity
NXW81_RS27450	COG0745	RESPONSE REGULATOR receiver
NXW81_RS27450	COG3292	Two component regulator propeller
NXW81_RS27450	COG0745	RESPONSE REGULATOR receiver
NXW81_RS27450	COG2205	protein histidine kinase activity
NXW81_RS27470	COG4206	TonB-dependent receptor
NXW81_RS27470	COG1629	transport
NXW81_RS27490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXW81_RS27500	COG3119	arylsulfatase activity
NXW81_RS27575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXW81_RS27580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXW81_RS27585	COG0166	Belongs to the GPI family
NXW81_RS27600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXW81_RS27615	COG2502	aspartate--ammonia ligase
NXW81_RS27620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXW81_RS27635	COG3876	Protein conserved in bacteria
NXW81_RS27665	COG2315	Protein conserved in bacteria
NXW81_RS27695	COG0860	N-Acetylmuramoyl-L-alanine amidase