locus-tag	class	description
NXX95_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NXX95_RS00020	COG1640	4-alpha-glucanotransferase
NXX95_RS00030	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NXX95_RS00040	COG1216	Glycosyl transferase, family 2
NXX95_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX95_RS00055	COG1022	Amp-dependent synthetase and ligase
NXX95_RS00090	COG0359	binds to the 23S rRNA
NXX95_RS00095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NXX95_RS00100	COG0360	Binds together with S18 to 16S ribosomal RNA
NXX95_RS00125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXX95_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXX95_RS00165	COG2431	L-lysine efflux transmembrane transporter activity
NXX95_RS00200	COG1373	ATPase (AAA superfamily
NXX95_RS00205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NXX95_RS00220	COG4206	TonB-dependent receptor
NXX95_RS00220	COG1629	transport
NXX95_RS00235	COG2234	aminopeptidase activity
NXX95_RS00245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NXX95_RS00250	COG0802	atpase or kinase
NXX95_RS00265	COG0714	Associated with various cellular activities
NXX95_RS00300	COG3118	belongs to the thioredoxin family
NXX95_RS00310	COG0688	phosphatidylethanolamine metabolic process
NXX95_RS00315	COG1183	phosphatidylcholine synthase activity
NXX95_RS00335	COG0792	nuclease activity
NXX95_RS00350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXX95_RS00365	COG0528	UMP kinase activity
NXX95_RS00380	COG3250	beta-galactosidase activity
NXX95_RS00390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS00395	COG1629	transport
NXX95_RS00395	COG4206	TonB-dependent receptor
NXX95_RS00400	COG0745	RESPONSE REGULATOR receiver
NXX95_RS00400	COG3292	Two component regulator propeller
NXX95_RS00400	COG2205	protein histidine kinase activity
NXX95_RS00410	COG0233	cytoplasmic translational termination
NXX95_RS00415	COG1162	GTPase activity
NXX95_RS00425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXX95_RS00440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NXX95_RS00440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NXX95_RS00455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NXX95_RS00470	COG4206	TonB-dependent receptor
NXX95_RS00470	COG1629	transport
NXX95_RS00475	COG4974	Belongs to the 'phage' integrase family
NXX95_RS00495	COG1629	transport
NXX95_RS00515	COG1629	transport
NXX95_RS00515	COG4206	TonB-dependent receptor
NXX95_RS00535	COG2095	MarC family integral membrane protein
NXX95_RS00550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXX95_RS00560	COG1435	thymidine kinase activity
NXX95_RS00575	COG4974	Belongs to the 'phage' integrase family
NXX95_RS00585	COG4584	PFAM Integrase catalytic
NXX95_RS00590	COG1484	DNA-dependent DNA replication
NXX95_RS00670	COG4974	Belongs to the 'phage' integrase family
NXX95_RS00705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXX95_RS00705	COG0551	DNA topoisomerase type I activity
NXX95_RS00740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS00740	COG2198	Histidine kinase
NXX95_RS00740	COG2205	protein histidine kinase activity
NXX95_RS00740	COG0784	Response regulator, receiver
NXX95_RS00750	COG2204	response regulator
NXX95_RS00955	COG1830	Aldolase
NXX95_RS00960	COG0588	phosphoglycerate mutase activity
NXX95_RS00970	COG1595	DNA-templated transcription, initiation
NXX95_RS00975	COG0205	6-phosphofructokinase activity
NXX95_RS00980	COG0058	SHG alpha-glucan phosphorylase activity
NXX95_RS00985	COG0010	Belongs to the arginase family
NXX95_RS00990	COG4413	Urea transporter
NXX95_RS00995	COG1396	sequence-specific DNA binding
NXX95_RS01005	COG4771	TonB-dependent receptor
NXX95_RS01065	COG2076	Multidrug Resistance protein
NXX95_RS01080	COG0475	glutathione-regulated potassium exporter activity
NXX95_RS01080	COG0589	response to stress
NXX95_RS01105	COG2207	Transcriptional regulator
NXX95_RS01115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXX95_RS01120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NXX95_RS01145	COG0110	maltose O-acetyltransferase activity
NXX95_RS01150	COG1522	sequence-specific DNA binding
NXX95_RS01165	COG0668	transmembrane transport
NXX95_RS01195	COG4771	TonB-dependent receptor
NXX95_RS01235	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
NXX95_RS01240	COG0527	aspartate kinase activity
NXX95_RS01240	COG0460	homoserine dehydrogenase
NXX95_RS01245	COG0252	asparaginase activity
NXX95_RS01255	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NXX95_RS01270	COG4771	TonB-dependent receptor
NXX95_RS01285	COG0826	peptidase U32
NXX95_RS01290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NXX95_RS01305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NXX95_RS01340	COG0582	viral genome integration into host DNA
NXX95_RS01380	COG0519	Catalyzes the synthesis of GMP from XMP
NXX95_RS01395	COG4771	TonB-dependent receptor
NXX95_RS01440	COG1131	(ABC) transporter
NXX95_RS01455	COG5002	protein histidine kinase activity
NXX95_RS01460	COG2205	protein histidine kinase activity
NXX95_RS01470	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NXX95_RS01475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NXX95_RS01480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NXX95_RS01525	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS01565	COG0582	viral genome integration into host DNA
NXX95_RS01600	COG4771	TonB-dependent receptor
NXX95_RS01615	COG0471	metal ion transport
NXX95_RS01665	COG0702	epimerase
NXX95_RS01670	COG4771	TonB-dependent receptor
NXX95_RS01695	COG0616	signal peptide processing
NXX95_RS01700	COG1663	tetraacyldisaccharide 4'-kinase activity
NXX95_RS01705	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NXX95_RS01710	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NXX95_RS01740	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS01770	COG0702	epimerase
NXX95_RS01775	COG1629	transport
NXX95_RS01930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXX95_RS01990	COG0784	Response regulator, receiver
NXX95_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS01990	COG2198	Histidine kinase
NXX95_RS01990	COG2205	protein histidine kinase activity
NXX95_RS02000	COG3408	Glycogen debranching enzyme
NXX95_RS02025	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS02045	COG1629	transport
NXX95_RS02055	COG1595	DNA-templated transcription, initiation
NXX95_RS02070	COG5433	transposase activity
NXX95_RS02180	COG0513	Belongs to the DEAD box helicase family
NXX95_RS02185	COG2070	2-Nitropropane dioxygenase
NXX95_RS02190	COG0724	RNA recognition motif
NXX95_RS02210	COG3973	AAA domain
NXX95_RS02225	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS02315	COG1401	restriction endodeoxyribonuclease activity
NXX95_RS02345	COG2204	response regulator
NXX95_RS02370	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS02375	COG0737	Belongs to the 5'-nucleotidase family
NXX95_RS02380	COG0737	Belongs to the 5'-nucleotidase family
NXX95_RS02395	COG0577	efflux transmembrane transporter activity
NXX95_RS02395	COG1136	(ABC) transporter
NXX95_RS02400	COG0577	efflux transmembrane transporter activity
NXX95_RS02400	COG1136	(ABC) transporter
NXX95_RS02405	COG0577	efflux transmembrane transporter activity
NXX95_RS02405	COG1136	(ABC) transporter
NXX95_RS02420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXX95_RS02420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NXX95_RS02445	COG2996	Protein conserved in bacteria
NXX95_RS02450	COG0039	L-malate dehydrogenase activity
NXX95_RS02460	COG2217	Heavy metal translocating P-type atpase
NXX95_RS02475	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NXX95_RS02480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NXX95_RS02485	COG0509	glycine decarboxylation via glycine cleavage system
NXX95_RS02500	COG0006	proline dipeptidase activity
NXX95_RS02505	COG3458	cephalosporin-C deacetylase activity
NXX95_RS02520	COG1283	sodium-dependent phosphate transmembrane transporter activity
NXX95_RS02525	COG1773	rubredoxin
NXX95_RS02535	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NXX95_RS02540	COG1011	Hydrolase
NXX95_RS02550	COG1266	CAAX protease self-immunity
NXX95_RS02555	COG2166	iron-sulfur cluster assembly
NXX95_RS02560	COG2234	aminopeptidase activity
NXX95_RS02565	COG1619	proteins homologs of microcin C7 resistance protein MccF
NXX95_RS02570	COG0280	phosphate acetyltransferase
NXX95_RS02575	COG3426	butyrate kinase activity
NXX95_RS02600	COG1185	polyribonucleotide nucleotidyltransferase activity
NXX95_RS02610	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NXX95_RS02630	COG0076	glutamate decarboxylase activity
NXX95_RS02645	COG0531	amino acid
NXX95_RS02665	COG3345	alpha-galactosidase
NXX95_RS02685	COG1131	(ABC) transporter
NXX95_RS02760	COG0667	Aldo Keto reductase
NXX95_RS02815	COG1696	Membrane protein involved in D-alanine export
NXX95_RS02850	COG1309	transcriptional regulator
NXX95_RS02855	COG2986	histidine ammonia-lyase
NXX95_RS02865	COG1228	amidohydrolase
NXX95_RS02875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NXX95_RS02885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXX95_RS02900	COG0203	ribosomal protein L17
NXX95_RS02905	COG0202	RNA polymerase activity
NXX95_RS02910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NXX95_RS02915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NXX95_RS02920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NXX95_RS02925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NXX95_RS02930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NXX95_RS02945	COG0200	Binds to the 23S rRNA
NXX95_RS02950	COG1841	ribosomal large subunit assembly
NXX95_RS02960	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NXX95_RS02965	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NXX95_RS02970	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NXX95_RS02975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NXX95_RS02980	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NXX95_RS02985	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NXX95_RS02990	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NXX95_RS02995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NXX95_RS03000	COG0255	Belongs to the universal ribosomal protein uL29 family
NXX95_RS03005	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NXX95_RS03010	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NXX95_RS03015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NXX95_RS03020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NXX95_RS03025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NXX95_RS03030	COG0089	rRNA binding
NXX95_RS03035	COG0088	Forms part of the polypeptide exit tunnel
NXX95_RS03040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NXX95_RS03045	COG0051	transcription antitermination factor activity, RNA binding
NXX95_RS03050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NXX95_RS03055	COG0049	tRNA binding
NXX95_RS03060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NXX95_RS03070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NXX95_RS03075	COG0085	RNA polymerase activity
NXX95_RS03080	COG0222	ribosome binding
NXX95_RS03085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NXX95_RS03090	COG0081	regulation of translation
NXX95_RS03095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NXX95_RS03105	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NXX95_RS03115	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NXX95_RS03145	COG4974	Belongs to the 'phage' integrase family
NXX95_RS03150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NXX95_RS03155	COG0006	proline dipeptidase activity
NXX95_RS03160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NXX95_RS03170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NXX95_RS03180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NXX95_RS03190	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NXX95_RS03215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXX95_RS03220	COG1027	Aspartate ammonia-lyase
NXX95_RS03230	COG4974	Belongs to the 'phage' integrase family
NXX95_RS03275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXX95_RS03290	COG1373	ATPase (AAA superfamily
NXX95_RS03295	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NXX95_RS03300	COG0252	asparaginase activity
NXX95_RS03315	COG4804	nuclease activity
NXX95_RS03320	COG2205	protein histidine kinase activity
NXX95_RS03320	COG3292	Two component regulator propeller
NXX95_RS03320	COG0745	RESPONSE REGULATOR receiver
NXX95_RS03325	COG0584	glycerophosphoryl diester phosphodiesterase
NXX95_RS03350	COG4206	TonB-dependent receptor
NXX95_RS03350	COG1629	transport
NXX95_RS03360	COG3940	Belongs to the glycosyl hydrolase 43 family
NXX95_RS03405	COG2096	Adenosyltransferase
NXX95_RS03460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX95_RS03465	COG0793	Belongs to the peptidase S41A family
NXX95_RS03470	COG0784	Response regulator, receiver
NXX95_RS03470	COG2205	protein histidine kinase activity
NXX95_RS03470	COG5002	protein histidine kinase activity
NXX95_RS03475	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NXX95_RS03505	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NXX95_RS03510	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NXX95_RS03525	COG2059	Chromate
NXX95_RS03540	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NXX95_RS03545	COG1396	sequence-specific DNA binding
NXX95_RS03550	COG0318	PFAM AMP-dependent synthetase and ligase
NXX95_RS03555	COG0662	Cupin 2, conserved barrel domain protein
NXX95_RS03555	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
NXX95_RS03590	COG1040	competence protein
NXX95_RS03635	COG2610	gluconate transmembrane transporter activity
NXX95_RS03640	COG1929	Belongs to the glycerate kinase type-1 family
NXX95_RS03660	COG1629	transport
NXX95_RS03680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX95_RS03690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX95_RS03700	COG1629	transport
NXX95_RS03705	COG0702	epimerase
NXX95_RS03730	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS03735	COG0004	ammonium transporteR
NXX95_RS03755	COG4771	TonB-dependent receptor
NXX95_RS03760	COG4771	TonB-dependent receptor
NXX95_RS03765	COG3292	Two component regulator propeller
NXX95_RS03765	COG2205	protein histidine kinase activity
NXX95_RS03765	COG0745	RESPONSE REGULATOR receiver
NXX95_RS03775	COG3634	alkyl hydroperoxide reductase activity
NXX95_RS03785	COG2816	NAD+ diphosphatase activity
NXX95_RS03845	COG0018	arginyl-trna synthetase
NXX95_RS03855	COG0705	Rhomboid family
NXX95_RS03870	COG0339	signal peptide processing
NXX95_RS03875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NXX95_RS03885	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXX95_RS03885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXX95_RS03890	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXX95_RS03905	COG1373	ATPase (AAA superfamily
NXX95_RS03915	COG3250	beta-galactosidase activity
NXX95_RS03920	COG3458	cephalosporin-C deacetylase activity
NXX95_RS03925	COG3345	alpha-galactosidase
NXX95_RS03930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXX95_RS03935	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS03970	COG4771	TonB-dependent receptor
NXX95_RS03985	COG4591	ABC-type transport system involved in lipoprotein release permease component
NXX95_RS03990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NXX95_RS04010	COG4974	Belongs to the 'phage' integrase family
NXX95_RS04025	COG0606	chelatase, subunit chli
NXX95_RS04030	COG2205	protein histidine kinase activity
NXX95_RS04050	COG3250	beta-galactosidase activity
NXX95_RS04085	COG4771	TonB-dependent receptor
NXX95_RS04095	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS04120	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS04125	COG1629	transport
NXX95_RS04125	COG4206	TonB-dependent receptor
NXX95_RS04140	COG0673	inositol 2-dehydrogenase activity
NXX95_RS04150	COG0673	inositol 2-dehydrogenase activity
NXX95_RS04155	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS04160	COG3292	Two component regulator propeller
NXX95_RS04160	COG2205	protein histidine kinase activity
NXX95_RS04160	COG0745	RESPONSE REGULATOR receiver
NXX95_RS04170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX95_RS04170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX95_RS04185	COG3475	LICD family
NXX95_RS04200	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS04230	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NXX95_RS04235	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX95_RS04240	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX95_RS04260	COG0561	phosphatase activity
NXX95_RS04325	COG4771	TonB-dependent receptor
NXX95_RS04330	COG0702	epimerase
NXX95_RS04340	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXX95_RS04350	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NXX95_RS04360	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXX95_RS04365	COG2211	Major facilitator Superfamily
NXX95_RS04370	COG3408	Glycogen debranching enzyme
NXX95_RS04395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NXX95_RS04400	COG3409	Peptidoglycan-binding domain 1 protein
NXX95_RS04400	COG0793	Belongs to the peptidase S41A family
NXX95_RS04410	COG3645	SOS response
NXX95_RS04430	COG1053	succinate dehydrogenase
NXX95_RS04435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NXX95_RS04530	COG0758	DNA mediated transformation
NXX95_RS04540	COG0826	peptidase U32
NXX95_RS04545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXX95_RS04605	COG0557	exoribonuclease II activity
NXX95_RS04615	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS04635	COG0702	epimerase
NXX95_RS04670	COG4206	TonB-dependent receptor
NXX95_RS04670	COG1629	transport
NXX95_RS04685	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS04690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXX95_RS04720	COG0657	acetylesterase activity
NXX95_RS04735	COG2271	Major facilitator Superfamily
NXX95_RS04740	COG1917	Cupin 2, conserved barrel domain protein
NXX95_RS04765	COG0702	epimerase
NXX95_RS04770	COG1629	transport
NXX95_RS04775	COG2186	Transcriptional regulator
NXX95_RS04795	COG0702	epimerase
NXX95_RS04800	COG4771	TonB-dependent receptor
NXX95_RS04845	COG0745	RESPONSE REGULATOR receiver
NXX95_RS04845	COG2205	protein histidine kinase activity
NXX95_RS04845	COG3292	Two component regulator propeller
NXX95_RS04865	COG1629	transport
NXX95_RS04865	COG4206	TonB-dependent receptor
NXX95_RS04875	COG1629	transport
NXX95_RS04875	COG4206	TonB-dependent receptor
NXX95_RS04900	COG3119	arylsulfatase activity
NXX95_RS04915	COG3385	transposase activity
NXX95_RS04940	COG0702	epimerase
NXX95_RS04945	COG1629	transport
NXX95_RS04945	COG4206	TonB-dependent receptor
NXX95_RS04960	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXX95_RS04965	COG0745	RESPONSE REGULATOR receiver
NXX95_RS04965	COG0745	RESPONSE REGULATOR receiver
NXX95_RS04965	COG2205	protein histidine kinase activity
NXX95_RS04965	COG2205	protein histidine kinase activity
NXX95_RS04965	COG3292	Two component regulator propeller
NXX95_RS04965	COG3292	Two component regulator propeller
NXX95_RS05025	COG4771	TonB-dependent receptor
NXX95_RS05030	COG2205	protein histidine kinase activity
NXX95_RS05030	COG0745	RESPONSE REGULATOR receiver
NXX95_RS05030	COG3292	Two component regulator propeller
NXX95_RS05060	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS05065	COG3250	beta-galactosidase activity
NXX95_RS05085	COG1484	DNA-dependent DNA replication
NXX95_RS05110	COG2814	Major facilitator Superfamily
NXX95_RS05115	COG0012	GTP binding
NXX95_RS05120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NXX95_RS05125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NXX95_RS05130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NXX95_RS05135	COG1629	transport
NXX95_RS05190	COG4771	TonB-dependent receptor
NXX95_RS05195	COG3537	Alpha-1,2-mannosidase
NXX95_RS05205	COG1785	Belongs to the alkaline phosphatase family
NXX95_RS05210	COG0697	spore germination
NXX95_RS05225	COG3250	beta-galactosidase activity
NXX95_RS05230	COG0495	leucyl-tRNA aminoacylation
NXX95_RS05235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXX95_RS05240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NXX95_RS05245	COG1360	Flagellar Motor Protein
NXX95_RS05255	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NXX95_RS05315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXX95_RS05315	COG0731	radical SAM domain protein
NXX95_RS05325	COG0784	Response regulator, receiver
NXX95_RS05325	COG2205	protein histidine kinase activity
NXX95_RS05325	COG2198	Histidine kinase
NXX95_RS05325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS05335	COG1629	transport
NXX95_RS05355	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS05430	COG1629	transport
NXX95_RS05430	COG4206	TonB-dependent receptor
NXX95_RS05445	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS05460	COG0659	secondary active sulfate transmembrane transporter activity
NXX95_RS05465	COG1592	Rubrerythrin
NXX95_RS05490	COG2027	D-alanyl-D-alanine carboxypeptidase
NXX95_RS05495	COG0427	acetyl-CoA hydrolase
NXX95_RS05505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX95_RS05530	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS05580	COG2177	Part of the ABC transporter FtsEX involved in
NXX95_RS05590	COG1968	undecaprenyl-diphosphatase activity
NXX95_RS05595	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NXX95_RS05600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXX95_RS05605	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NXX95_RS05615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NXX95_RS05645	COG0594	ribonuclease P activity
NXX95_RS05650	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NXX95_RS05660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NXX95_RS05680	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXX95_RS05685	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS05720	COG0726	polysaccharide deacetylase
NXX95_RS05730	COG1121	(ABC) transporter
NXX95_RS05740	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NXX95_RS05740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NXX95_RS05745	COG1238	metal cluster binding
NXX95_RS05760	COG1506	peptidase
NXX95_RS05760	COG0823	Involved in the tonB-independent uptake of proteins
NXX95_RS05770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXX95_RS05770	COG0116	Belongs to the methyltransferase superfamily
NXX95_RS05775	COG1045	serine acetyltransferase
NXX95_RS05785	COG3279	Response regulator of the LytR AlgR family
NXX95_RS05805	COG0142	geranyltranstransferase activity
NXX95_RS05815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NXX95_RS05820	COG1694	Mazg nucleotide pyrophosphohydrolase
NXX95_RS05825	COG1490	D-aminoacyl-tRNA deacylase activity
NXX95_RS05830	COG0322	excinuclease ABC activity
NXX95_RS05835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXX95_RS05840	COG0445	tRNA wobble uridine modification
NXX95_RS05855	COG4771	TonB-dependent receptor
NXX95_RS05895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NXX95_RS05900	COG2715	membrane protein required for spore maturation
NXX95_RS05905	COG2255	four-way junction helicase activity
NXX95_RS05925	COG3591	Belongs to the peptidase S1B family
NXX95_RS05950	COG0702	epimerase
NXX95_RS05955	COG1629	transport
NXX95_RS05955	COG4206	TonB-dependent receptor
NXX95_RS05960	COG2205	protein histidine kinase activity
NXX95_RS05960	COG0745	RESPONSE REGULATOR receiver
NXX95_RS05960	COG3292	Two component regulator propeller
NXX95_RS05965	COG0513	Belongs to the DEAD box helicase family
NXX95_RS05970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NXX95_RS05985	COG0612	Peptidase, M16
NXX95_RS05995	COG0584	glycerophosphoryl diester phosphodiesterase
NXX95_RS06015	COG0702	epimerase
NXX95_RS06020	COG1629	transport
NXX95_RS06025	COG1629	transport
NXX95_RS06035	COG1595	DNA-templated transcription, initiation
NXX95_RS06050	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NXX95_RS06065	COG1629	transport
NXX95_RS06065	COG4206	TonB-dependent receptor
NXX95_RS06090	COG0584	glycerophosphoryl diester phosphodiesterase
NXX95_RS06105	COG4771	TonB-dependent receptor
NXX95_RS06110	COG0702	epimerase
NXX95_RS06125	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS06150	COG0681	Belongs to the peptidase S26 family
NXX95_RS06160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NXX95_RS06190	COG1215	transferase activity, transferring glycosyl groups
NXX95_RS06210	COG5492	domain, Protein
NXX95_RS06220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NXX95_RS06230	COG0702	epimerase
NXX95_RS06235	COG4771	TonB-dependent receptor
NXX95_RS06245	COG0745	RESPONSE REGULATOR receiver
NXX95_RS06245	COG2205	protein histidine kinase activity
NXX95_RS06245	COG3292	Two component regulator propeller
NXX95_RS06245	COG0745	RESPONSE REGULATOR receiver
NXX95_RS06245	COG3292	Two component regulator propeller
NXX95_RS06245	COG2205	protein histidine kinase activity
NXX95_RS06265	COG0702	epimerase
NXX95_RS06270	COG1629	transport
NXX95_RS06280	COG1629	transport
NXX95_RS06300	COG0738	Major facilitator superfamily
NXX95_RS06315	COG1940	carbohydrate kinase activity
NXX95_RS06320	COG3250	beta-galactosidase activity
NXX95_RS06330	COG1609	Transcriptional regulator
NXX95_RS06340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX95_RS06345	COG1538	Outer membrane efflux protein
NXX95_RS06355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX95_RS06360	COG3250	beta-galactosidase activity
NXX95_RS06410	COG4771	TonB-dependent receptor
NXX95_RS06415	COG4206	TonB-dependent receptor
NXX95_RS06415	COG1629	transport
NXX95_RS06425	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS06430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NXX95_RS06440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS06445	COG3119	arylsulfatase activity
NXX95_RS06450	COG5492	domain, Protein
NXX95_RS06455	COG0215	cysteine-tRNA ligase activity
NXX95_RS06460	COG0561	phosphatase activity
NXX95_RS06475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXX95_RS06480	COG0482	sulfurtransferase activity
NXX95_RS06495	COG0205	6-phosphofructokinase activity
NXX95_RS06500	COG0571	ribonuclease III activity
NXX95_RS06505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXX95_RS06510	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXX95_RS06520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NXX95_RS06560	COG3475	LICD family
NXX95_RS06565	COG4750	Nucleotidyl transferase
NXX95_RS06580	COG1216	Glycosyl transferase, family 2
NXX95_RS06580	COG1442	glycosyl transferase family 8
NXX95_RS06585	COG0463	Glycosyl transferase, family 2
NXX95_RS06600	COG1216	Glycosyl transferase, family 2
NXX95_RS06605	COG1442	glycosyl transferase family 8
NXX95_RS06605	COG1216	Glycosyl transferase, family 2
NXX95_RS06625	COG3385	transposase activity
NXX95_RS06685	COG1132	(ABC) transporter
NXX95_RS06695	COG0463	Glycosyl transferase, family 2
NXX95_RS06705	COG1368	sulfuric ester hydrolase activity
NXX95_RS06715	COG3341	Caulimovirus viroplasmin
NXX95_RS06715	COG0328	RNA-DNA hybrid ribonuclease activity
NXX95_RS06725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NXX95_RS06735	COG0326	Molecular chaperone. Has ATPase activity
NXX95_RS06745	COG1166	arginine decarboxylase activity
NXX95_RS06755	COG1595	DNA-templated transcription, initiation
NXX95_RS06780	COG0779	Required for maturation of 30S ribosomal subunits
NXX95_RS06785	COG0195	Participates in both transcription termination and antitermination
NXX95_RS06790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NXX95_RS06800	COG0719	Fe-S assembly protein
NXX95_RS06805	COG0396	ATPase activity
NXX95_RS06810	COG0719	Fe-S assembly protein
NXX95_RS06815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NXX95_RS06820	COG0393	Putative heavy-metal-binding
NXX95_RS06840	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
NXX95_RS06845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NXX95_RS06860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NXX95_RS06870	COG0187	DNA topoisomerase II activity
NXX95_RS06895	COG0268	Binds directly to 16S ribosomal RNA
NXX95_RS06905	COG1381	Involved in DNA repair and RecF pathway recombination
NXX95_RS06960	COG1610	YqeY-like protein
NXX95_RS06965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NXX95_RS06980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NXX95_RS06985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NXX95_RS06995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NXX95_RS07000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NXX95_RS07005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NXX95_RS07020	COG0275	rRNA processing
NXX95_RS07025	COG2001	Belongs to the MraZ family
NXX95_RS07030	COG1595	DNA-templated transcription, initiation
NXX95_RS07045	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NXX95_RS07050	COG0756	dUTP diphosphatase activity
NXX95_RS07065	COG4942	peptidase
NXX95_RS07070	COG3292	Two component regulator propeller
NXX95_RS07070	COG0745	RESPONSE REGULATOR receiver
NXX95_RS07070	COG2205	protein histidine kinase activity
NXX95_RS07085	COG3119	arylsulfatase activity
NXX95_RS07100	COG4771	TonB-dependent receptor
NXX95_RS07110	COG1629	transport
NXX95_RS07110	COG4206	TonB-dependent receptor
NXX95_RS07140	COG0702	epimerase
NXX95_RS07145	COG4771	TonB-dependent receptor
NXX95_RS07155	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS07205	COG3119	arylsulfatase activity
NXX95_RS07235	COG3119	arylsulfatase activity
NXX95_RS07245	COG3119	arylsulfatase activity
NXX95_RS07260	COG3119	arylsulfatase activity
NXX95_RS07265	COG3408	Glycogen debranching enzyme
NXX95_RS07265	COG3119	arylsulfatase activity
NXX95_RS07285	COG4771	TonB-dependent receptor
NXX95_RS07295	COG4771	TonB-dependent receptor
NXX95_RS07320	COG3661	Belongs to the glycosyl hydrolase 67 family
NXX95_RS07325	COG3119	arylsulfatase activity
NXX95_RS07355	COG4771	TonB-dependent receptor
NXX95_RS07360	COG0561	phosphatase activity
NXX95_RS07440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX95_RS07445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NXX95_RS07450	COG1022	Amp-dependent synthetase and ligase
NXX95_RS07475	COG2954	triphosphatase activity
NXX95_RS07515	COG3591	Belongs to the peptidase S1B family
NXX95_RS07515	COG1864	DNA RNA non-specific endonuclease
NXX95_RS07550	COG0561	phosphatase activity
NXX95_RS07555	COG4771	TonB-dependent receptor
NXX95_RS07585	COG2271	Major facilitator Superfamily
NXX95_RS07595	COG1629	transport
NXX95_RS07635	COG1595	DNA-templated transcription, initiation
NXX95_RS07640	COG0673	inositol 2-dehydrogenase activity
NXX95_RS07650	COG0673	inositol 2-dehydrogenase activity
NXX95_RS07675	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NXX95_RS07690	COG0702	epimerase
NXX95_RS07695	COG1629	transport
NXX95_RS07705	COG1609	Transcriptional regulator
NXX95_RS07705	COG2207	Transcriptional regulator
NXX95_RS07735	COG0423	glycine-tRNA ligase activity
NXX95_RS07750	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXX95_RS07750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NXX95_RS07765	COG1609	Transcriptional regulator
NXX95_RS07780	COG0738	Major facilitator superfamily
NXX95_RS07785	COG1063	alcohol dehydrogenase
NXX95_RS07795	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS07805	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS07810	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX95_RS07820	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS07830	COG4771	TonB-dependent receptor
NXX95_RS07840	COG1629	transport
NXX95_RS07870	COG2382	esterase
NXX95_RS07875	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS07880	COG3292	Two component regulator propeller
NXX95_RS07880	COG2205	protein histidine kinase activity
NXX95_RS07880	COG0745	RESPONSE REGULATOR receiver
NXX95_RS07895	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NXX95_RS07905	COG2211	Major facilitator Superfamily
NXX95_RS07920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX95_RS07980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NXX95_RS07985	COG0475	glutathione-regulated potassium exporter activity
NXX95_RS07985	COG0589	response to stress
NXX95_RS07990	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NXX95_RS07995	COG1136	(ABC) transporter
NXX95_RS08005	COG0733	neurotransmitter:sodium symporter activity
NXX95_RS08015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NXX95_RS08020	COG5002	protein histidine kinase activity
NXX95_RS08020	COG0784	Response regulator, receiver
NXX95_RS08025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NXX95_RS08030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NXX95_RS08050	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS08060	COG4206	TonB-dependent receptor
NXX95_RS08060	COG1629	transport
NXX95_RS08075	COG4977	sequence-specific DNA binding
NXX95_RS08090	COG3507	Belongs to the glycosyl hydrolase 43 family
NXX95_RS08120	COG1346	cytolysis
NXX95_RS08125	COG1380	Effector of murein hydrolase LrgA
NXX95_RS08130	COG0280	phosphate acetyltransferase
NXX95_RS08135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NXX95_RS08150	COG1216	Glycosyl transferase, family 2
NXX95_RS08150	COG0463	Glycosyl transferase, family 2
NXX95_RS08155	COG2003	Belongs to the UPF0758 family
NXX95_RS08230	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS08235	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS08255	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS08260	COG4771	TonB-dependent receptor
NXX95_RS08410	COG1475	DNA binding
NXX95_RS08435	COG4771	TonB-dependent receptor
NXX95_RS08455	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX95_RS08460	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS08465	COG2205	protein histidine kinase activity
NXX95_RS08465	COG0784	Response regulator, receiver
NXX95_RS08505	COG1040	competence protein
NXX95_RS08530	COG4974	Belongs to the 'phage' integrase family
NXX95_RS08550	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS08555	COG1629	transport
NXX95_RS08555	COG4206	TonB-dependent receptor
NXX95_RS08560	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS08565	COG0366	Alpha amylase catalytic
NXX95_RS08575	COG1785	Belongs to the alkaline phosphatase family
NXX95_RS08580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NXX95_RS08585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NXX95_RS08590	COG0515	serine threonine protein kinase
NXX95_RS08590	COG2815	serine threonine protein kinase
NXX95_RS08595	COG0564	pseudouridine synthase activity
NXX95_RS08620	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NXX95_RS08625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NXX95_RS08635	COG0436	Aminotransferase
NXX95_RS08645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NXX95_RS08660	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NXX95_RS08665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NXX95_RS08675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXX95_RS08675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NXX95_RS08680	COG2890	protein-(glutamine-N5) methyltransferase activity
NXX95_RS08690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NXX95_RS08700	COG0165	Argininosuccinate lyase
NXX95_RS08750	COG0582	viral genome integration into host DNA
NXX95_RS08835	COG1629	transport
NXX95_RS08835	COG4206	TonB-dependent receptor
NXX95_RS08865	COG4771	TonB-dependent receptor
NXX95_RS08910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NXX95_RS08915	COG1917	Cupin 2, conserved barrel domain protein
NXX95_RS08915	COG1396	sequence-specific DNA binding
NXX95_RS08925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NXX95_RS08930	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NXX95_RS08935	COG0137	argininosuccinate synthase activity
NXX95_RS08945	COG1438	arginine binding
NXX95_RS08960	COG1629	transport
NXX95_RS08965	COG0561	phosphatase activity
NXX95_RS08980	COG1070	Carbohydrate kinase
NXX95_RS08985	COG4806	L-rhamnose isomerase
NXX95_RS08995	COG0235	Class ii aldolase
NXX95_RS09000	COG1454	alcohol dehydrogenase
NXX95_RS09010	COG3292	Two component regulator propeller
NXX95_RS09010	COG0745	RESPONSE REGULATOR receiver
NXX95_RS09010	COG2205	protein histidine kinase activity
NXX95_RS09015	COG4771	TonB-dependent receptor
NXX95_RS09020	COG0702	epimerase
NXX95_RS09050	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX95_RS09055	COG3250	beta-galactosidase activity
NXX95_RS09125	COG0582	viral genome integration into host DNA
NXX95_RS09170	COG0564	pseudouridine synthase activity
NXX95_RS09200	COG3537	Alpha-1,2-mannosidase
NXX95_RS09205	COG0745	RESPONSE REGULATOR receiver
NXX95_RS09205	COG2205	protein histidine kinase activity
NXX95_RS09205	COG3292	Two component regulator propeller
NXX95_RS09245	COG3119	arylsulfatase activity
NXX95_RS09250	COG2204	response regulator
NXX95_RS09255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXX95_RS09255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NXX95_RS09260	COG0612	Peptidase, M16
NXX95_RS09265	COG0534	Mate efflux family protein
NXX95_RS09270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS09270	COG2205	protein histidine kinase activity
NXX95_RS09290	COG0488	(ABC) transporter
NXX95_RS09295	COG3590	peptidase
NXX95_RS09300	COG0138	bifunctional purine biosynthesis protein purh
NXX95_RS09325	COG0772	Belongs to the SEDS family
NXX95_RS09335	COG1774	PSP1 C-terminal conserved region
NXX95_RS09340	COG0470	DNA polymerase III
NXX95_RS09345	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NXX95_RS09350	COG2193	ferroxidase activity
NXX95_RS09405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXX95_RS09410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NXX95_RS09415	COG1160	GTP binding
NXX95_RS09425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NXX95_RS09430	COG1127	ABC transporter
NXX95_RS09435	COG0724	RNA recognition motif
NXX95_RS09440	COG0544	peptidyl-prolyl cis-trans isomerase activity
NXX95_RS09445	COG0740	serine-type endopeptidase activity
NXX95_RS09450	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NXX95_RS09460	COG0517	IMP dehydrogenase activity
NXX95_RS09460	COG0516	GMP reductase activity
NXX95_RS09465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXX95_RS09475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXX95_RS09490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NXX95_RS09530	COG3022	response to hydroperoxide
NXX95_RS09535	COG0110	maltose O-acetyltransferase activity
NXX95_RS09600	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NXX95_RS09620	COG1187	pseudouridine synthase activity
NXX95_RS09625	COG0017	Asparaginyl-tRNA synthetase
NXX95_RS09650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NXX95_RS09655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NXX95_RS09660	COG0052	Belongs to the universal ribosomal protein uS2 family
NXX95_RS09665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NXX95_RS09680	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NXX95_RS09685	COG0179	Fumarylacetoacetate (FAA) hydrolase
NXX95_RS09690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NXX95_RS09705	COG0482	sulfurtransferase activity
NXX95_RS09715	COG1570	exodeoxyribonuclease VII activity
NXX95_RS09725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXX95_RS09735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NXX95_RS09740	COG0489	protein tyrosine kinase activity
NXX95_RS09745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX95_RS09785	COG0039	L-malate dehydrogenase activity
NXX95_RS09800	COG4771	TonB-dependent receptor
NXX95_RS09840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NXX95_RS09845	COG0811	peptide transport
NXX95_RS09850	COG0848	biopolymer transport protein
NXX95_RS09865	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NXX95_RS09870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NXX95_RS09875	COG0105	UTP biosynthetic process
NXX95_RS09880	COG0739	heme binding
NXX95_RS09895	COG0149	triose-phosphate isomerase activity
NXX95_RS09905	COG0302	gtp cyclohydrolase
NXX95_RS09910	COG0358	DNA primase activity
NXX95_RS09920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NXX95_RS09945	COG0514	ATP-dependent DNA helicase (RecQ)
NXX95_RS10000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXX95_RS10015	COG0726	polysaccharide deacetylase
NXX95_RS10025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXX95_RS10030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXX95_RS10040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXX95_RS10050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXX95_RS10065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NXX95_RS10070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NXX95_RS10075	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS10090	COG0009	L-threonylcarbamoyladenylate synthase
NXX95_RS10100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXX95_RS10105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NXX95_RS10115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NXX95_RS10125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXX95_RS10135	COG4771	TonB-dependent receptor
NXX95_RS10140	COG4771	TonB-dependent receptor
NXX95_RS10150	COG3537	Alpha-1,2-mannosidase
NXX95_RS10155	COG3537	Alpha-1,2-mannosidase
NXX95_RS10165	COG3537	Alpha-1,2-mannosidase
NXX95_RS10170	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS10175	COG3279	Response regulator of the LytR AlgR family
NXX95_RS10180	COG3275	phosphorelay sensor kinase activity
NXX95_RS10195	COG0386	Belongs to the glutathione peroxidase family
NXX95_RS10205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NXX95_RS10220	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NXX95_RS10235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXX95_RS10240	COG0742	ribosomal rna small subunit methyltransferase
NXX95_RS10255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXX95_RS10285	COG4206	TonB-dependent receptor
NXX95_RS10285	COG1629	transport
NXX95_RS10315	COG3537	Alpha-1,2-mannosidase
NXX95_RS10340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXX95_RS10395	COG0582	viral genome integration into host DNA
NXX95_RS10445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX95_RS10460	COG0739	heme binding
NXX95_RS10470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXX95_RS10475	COG1388	LysM domain
NXX95_RS10475	COG0741	lytic transglycosylase activity
NXX95_RS10485	COG1475	DNA binding
NXX95_RS10490	COG1192	Involved in chromosome partitioning
NXX95_RS10495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NXX95_RS10500	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX95_RS10510	COG4589	Belongs to the CDS family
NXX95_RS10515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXX95_RS10615	COG1196	nuclear chromosome segregation
NXX95_RS10620	COG2239	Acts as a magnesium transporter
NXX95_RS10625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NXX95_RS10635	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX95_RS10675	COG0668	transmembrane transport
NXX95_RS10680	COG2207	Transcriptional regulator
NXX95_RS10680	COG0662	Cupin 2, conserved barrel domain protein
NXX95_RS10710	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX95_RS10715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NXX95_RS10720	COG0713	ATP synthesis coupled electron transport
NXX95_RS10735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NXX95_RS10740	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX95_RS10740	COG0649	NAD binding
NXX95_RS10745	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX95_RS10750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NXX95_RS10785	COG3250	beta-galactosidase activity
NXX95_RS10795	COG3250	beta-galactosidase activity
NXX95_RS10815	COG0702	epimerase
NXX95_RS10835	COG4771	TonB-dependent receptor
NXX95_RS10840	COG0702	epimerase
NXX95_RS10845	COG1629	transport
NXX95_RS10845	COG4206	TonB-dependent receptor
NXX95_RS10860	COG3119	arylsulfatase activity
NXX95_RS10870	COG3537	Alpha-1,2-mannosidase
NXX95_RS10885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXX95_RS10890	COG0569	domain protein
NXX95_RS10895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXX95_RS10915	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NXX95_RS10920	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NXX95_RS10940	COG2271	Major facilitator Superfamily
NXX95_RS10945	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NXX95_RS10950	COG3775	system Galactitol-specific IIC component
NXX95_RS10955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS10965	COG2755	lipolytic protein G-D-S-L family
NXX95_RS10975	COG3292	Two component regulator propeller
NXX95_RS10975	COG0745	RESPONSE REGULATOR receiver
NXX95_RS10975	COG2205	protein histidine kinase activity
NXX95_RS10985	COG0702	epimerase
NXX95_RS11010	COG3279	Response regulator of the LytR AlgR family
NXX95_RS11015	COG1242	4 iron, 4 sulfur cluster binding
NXX95_RS11025	COG0363	glucosamine-6-phosphate deaminase activity
NXX95_RS11030	COG0009	L-threonylcarbamoyladenylate synthase
NXX95_RS11040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NXX95_RS11045	COG0561	phosphatase activity
NXX95_RS11050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXX95_RS11075	COG2755	lipolytic protein G-D-S-L family
NXX95_RS11110	COG1629	transport
NXX95_RS11135	COG4771	TonB-dependent receptor
NXX95_RS11155	COG3401	FG-GAP repeat protein
NXX95_RS11165	COG2755	lipolytic protein G-D-S-L family
NXX95_RS11175	COG3401	FG-GAP repeat protein
NXX95_RS11185	COG3254	rhamnose metabolic process
NXX95_RS11210	COG3250	beta-galactosidase activity
NXX95_RS11215	COG3401	FG-GAP repeat protein
NXX95_RS11225	COG4733	cellulase activity
NXX95_RS11240	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS11265	COG4771	TonB-dependent receptor
NXX95_RS11270	COG0702	epimerase
NXX95_RS11285	COG4771	TonB-dependent receptor
NXX95_RS11375	COG0745	RESPONSE REGULATOR receiver
NXX95_RS11375	COG2205	protein histidine kinase activity
NXX95_RS11375	COG3292	Two component regulator propeller
NXX95_RS11375	COG0745	RESPONSE REGULATOR receiver
NXX95_RS11375	COG2205	protein histidine kinase activity
NXX95_RS11375	COG3292	Two component regulator propeller
NXX95_RS11395	COG0546	phosphoglycolate phosphatase activity
NXX95_RS11450	COG0582	viral genome integration into host DNA
NXX95_RS11485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NXX95_RS11495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NXX95_RS11505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NXX95_RS11510	COG0823	Involved in the tonB-independent uptake of proteins
NXX95_RS11510	COG1506	peptidase
NXX95_RS11520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXX95_RS11535	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NXX95_RS11535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NXX95_RS11540	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NXX95_RS11545	COG1078	dGTPase activity
NXX95_RS11550	COG0284	orotidine-5'-phosphate decarboxylase activity
NXX95_RS11555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NXX95_RS11560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NXX95_RS11565	COG1704	LemA family
NXX95_RS11580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NXX95_RS11585	COG2226	methyltransferase
NXX95_RS11590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NXX95_RS11595	COG1702	phosphate starvation-inducible protein PhoH
NXX95_RS11620	COG2268	Band 7 protein
NXX95_RS11630	COG0101	tRNA pseudouridine synthase activity
NXX95_RS11650	COG3250	beta-galactosidase activity
NXX95_RS11655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NXX95_RS11660	COG0673	inositol 2-dehydrogenase activity
NXX95_RS11675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NXX95_RS11685	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NXX95_RS11700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NXX95_RS11705	COG0793	Belongs to the peptidase S41A family
NXX95_RS11710	COG2131	deaminase
NXX95_RS11720	COG0339	signal peptide processing
NXX95_RS11730	COG1970	mechanosensitive ion channel activity
NXX95_RS11735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NXX95_RS11735	COG0519	Catalyzes the synthesis of GMP from XMP
NXX95_RS11760	COG4206	TonB-dependent receptor
NXX95_RS11760	COG1629	transport
NXX95_RS11765	COG4771	TonB-dependent receptor
NXX95_RS11770	COG0561	phosphatase activity
NXX95_RS11805	COG0297	glycogen (starch) synthase activity
NXX95_RS11825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NXX95_RS11830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NXX95_RS11835	COG0543	2 iron, 2 sulfur cluster binding
NXX95_RS11840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NXX95_RS11845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NXX95_RS11850	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NXX95_RS11865	COG0791	NLP P60 protein
NXX95_RS11880	COG0612	Peptidase, M16
NXX95_RS11885	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NXX95_RS11890	COG1597	lipid kinase activity
NXX95_RS11895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NXX95_RS11910	COG1136	(ABC) transporter
NXX95_RS11930	COG2211	Major facilitator Superfamily
NXX95_RS11935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NXX95_RS11950	COG1674	ftsk spoiiie
NXX95_RS11960	COG0492	ferredoxin-NADP+ reductase activity
NXX95_RS11965	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS12015	COG4206	TonB-dependent receptor
NXX95_RS12015	COG1629	transport
NXX95_RS12070	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX95_RS12070	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX95_RS12080	COG1234	tRNA 3'-trailer cleavage
NXX95_RS12085	COG2989	Protein conserved in bacteria
NXX95_RS12105	COG3956	TIGRFAM MazG family protein
NXX95_RS12155	COG0525	valine-tRNA ligase activity
NXX95_RS12160	COG0784	Response regulator, receiver
NXX95_RS12160	COG2205	protein histidine kinase activity
NXX95_RS12175	COG4206	TonB-dependent receptor
NXX95_RS12175	COG1629	transport
NXX95_RS12180	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS12205	COG0653	protein targeting
NXX95_RS12210	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
NXX95_RS12225	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NXX95_RS12245	COG1253	flavin adenine dinucleotide binding
NXX95_RS12250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NXX95_RS12260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NXX95_RS12270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NXX95_RS12275	COG2204	response regulator
NXX95_RS12315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NXX95_RS12315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NXX95_RS12330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NXX95_RS12335	COG0563	adenylate kinase activity
NXX95_RS12340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NXX95_RS12345	COG1496	oxidoreductase activity
NXX95_RS12370	COG4804	nuclease activity
NXX95_RS12425	COG3142	Participates in the control of copper homeostasis
NXX95_RS12430	COG1418	mRNA catabolic process
NXX95_RS12600	COG0622	Phosphoesterase
NXX95_RS12645	COG1132	(ABC) transporter
NXX95_RS12650	COG1132	(ABC) transporter
NXX95_RS12650	COG2375	cellular response to nickel ion
NXX95_RS12660	COG0428	transporter
NXX95_RS12710	COG3015	lipoprotein NlpE involved in copper resistance
NXX95_RS12830	COG4372	Transposase
NXX95_RS12835	COG2433	Pfam Transposase IS66
NXX95_RS12905	COG0702	epimerase
NXX95_RS12910	COG1629	transport
NXX95_RS12915	COG3292	Two component regulator propeller
NXX95_RS12915	COG2205	protein histidine kinase activity
NXX95_RS12915	COG0745	RESPONSE REGULATOR receiver
NXX95_RS12945	COG2095	MarC family integral membrane protein
NXX95_RS12955	COG1830	Aldolase
NXX95_RS12960	COG0588	phosphoglycerate mutase activity
NXX95_RS12980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXX95_RS12980	COG4651	solute:proton antiporter activity
NXX95_RS12985	COG0058	SHG alpha-glucan phosphorylase activity
NXX95_RS12990	COG0010	Belongs to the arginase family
NXX95_RS13000	COG2205	protein histidine kinase activity
NXX95_RS13000	COG2198	Histidine kinase
NXX95_RS13000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS13000	COG0784	Response regulator, receiver
NXX95_RS13055	COG0739	heme binding
NXX95_RS13135	COG4974	Belongs to the 'phage' integrase family
NXX95_RS13165	COG4771	TonB-dependent receptor
NXX95_RS13170	COG0702	epimerase
NXX95_RS13200	COG0246	Mannitol dehydrogenase
NXX95_RS13210	COG1063	alcohol dehydrogenase
NXX95_RS13220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXX95_RS13225	COG2832	Protein of unknown function (DUF454)
NXX95_RS13235	COG0602	queuosine metabolic process
NXX95_RS13240	COG0247	lactate metabolic process
NXX95_RS13245	COG1139	Iron-sulfur cluster binding protein
NXX95_RS13255	COG0351	phosphomethylpyrimidine kinase
NXX95_RS13275	COG4589	Belongs to the CDS family
NXX95_RS13285	COG2304	oxidoreductase activity
NXX95_RS13400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NXX95_RS13540	COG1393	Belongs to the ArsC family
NXX95_RS13550	COG4771	TonB-dependent receptor
NXX95_RS13565	COG2233	PERMEase
NXX95_RS13570	COG1509	lysine 2,3-aminomutase activity
NXX95_RS13580	COG1115	amino acid carrier protein
NXX95_RS13615	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS13625	COG0776	regulation of translation
NXX95_RS13655	COG1285	pathogenesis
NXX95_RS13675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NXX95_RS13680	COG1388	LysM domain
NXX95_RS13680	COG0741	lytic transglycosylase activity
NXX95_RS13715	COG0534	Mate efflux family protein
NXX95_RS13725	COG0564	pseudouridine synthase activity
NXX95_RS13795	COG1396	sequence-specific DNA binding
NXX95_RS13815	COG0732	type I restriction modification DNA specificity domain
NXX95_RS13830	COG4974	Belongs to the 'phage' integrase family
NXX95_RS13855	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX95_RS13860	COG1063	alcohol dehydrogenase
NXX95_RS13875	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXX95_RS13880	COG2205	protein histidine kinase activity
NXX95_RS13880	COG0784	Response regulator, receiver
NXX95_RS13885	COG0702	epimerase
NXX95_RS13895	COG4864	UPF0365 protein
NXX95_RS13910	COG0037	tRNA processing
NXX95_RS13920	COG1477	protein flavinylation
NXX95_RS13925	COG1971	Probably functions as a manganese efflux pump
NXX95_RS13940	COG0463	Glycosyl transferase, family 2
NXX95_RS13965	COG0148	phosphopyruvate hydratase activity
NXX95_RS13975	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NXX95_RS13980	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS13985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NXX95_RS13990	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX95_RS14000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXX95_RS14000	COG4651	solute:proton antiporter activity
NXX95_RS14010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NXX95_RS14015	COG0193	aminoacyl-tRNA hydrolase activity
NXX95_RS14020	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NXX95_RS14030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NXX95_RS14045	COG0237	dephospho-CoA kinase activity
NXX95_RS14060	COG0542	response to heat
NXX95_RS14075	COG0583	DNA-binding transcription factor activity
NXX95_RS14105	COG0443	Heat shock 70 kDa protein
NXX95_RS14110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NXX95_RS14120	COG1373	ATPase (AAA superfamily
NXX95_RS14125	COG3304	Inner membrane component domain
NXX95_RS14130	COG2855	membrane
NXX95_RS14135	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NXX95_RS14140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NXX95_RS14180	COG4974	Belongs to the 'phage' integrase family
NXX95_RS14205	COG0732	type I restriction modification DNA specificity domain
NXX95_RS14215	COG4974	Belongs to the 'phage' integrase family
NXX95_RS14220	COG0732	type I restriction modification DNA specificity domain
NXX95_RS14225	COG0732	type I restriction modification DNA specificity domain
NXX95_RS14235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NXX95_RS14260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NXX95_RS14260	COG4651	solute:proton antiporter activity
NXX95_RS14265	COG0306	phosphate transporter
NXX95_RS14275	COG0586	Pfam SNARE associated Golgi protein
NXX95_RS14335	COG2205	protein histidine kinase activity
NXX95_RS14335	COG0745	RESPONSE REGULATOR receiver
NXX95_RS14335	COG3292	Two component regulator propeller
NXX95_RS14345	COG3119	arylsulfatase activity
NXX95_RS14350	COG3119	arylsulfatase activity
NXX95_RS14355	COG3119	arylsulfatase activity
NXX95_RS14360	COG3119	arylsulfatase activity
NXX95_RS14370	COG4771	TonB-dependent receptor
NXX95_RS14375	COG0702	epimerase
NXX95_RS14380	COG3119	arylsulfatase activity
NXX95_RS14385	COG3119	arylsulfatase activity
NXX95_RS14390	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS14395	COG0038	chloride channel
NXX95_RS14405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NXX95_RS14420	COG1940	carbohydrate kinase activity
NXX95_RS14430	COG3119	arylsulfatase activity
NXX95_RS14440	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS14460	COG0702	epimerase
NXX95_RS14475	COG5434	Belongs to the glycosyl hydrolase 28 family
NXX95_RS14485	COG0745	RESPONSE REGULATOR receiver
NXX95_RS14485	COG3292	Two component regulator propeller
NXX95_RS14485	COG2205	protein histidine kinase activity
NXX95_RS14490	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NXX95_RS14495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NXX95_RS14505	COG3250	beta-galactosidase activity
NXX95_RS14520	COG4974	Belongs to the 'phage' integrase family
NXX95_RS14550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXX95_RS14620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXX95_RS14640	COG1760	l-serine dehydratase
NXX95_RS14645	COG0598	Magnesium transport protein CorA
NXX95_RS14650	COG1193	negative regulation of DNA recombination
NXX95_RS14660	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NXX95_RS14665	COG0456	acetyltransferase
NXX95_RS14675	COG3189	MarR family transcriptional regulator
NXX95_RS14680	COG0561	phosphatase activity
NXX95_RS14685	COG1169	isochorismate synthase
NXX95_RS14690	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXX95_RS14695	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NXX95_RS14700	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS14710	COG0783	Belongs to the Dps family
NXX95_RS14715	COG0583	DNA-binding transcription factor activity
NXX95_RS14725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NXX95_RS14750	COG1595	DNA-templated transcription, initiation
NXX95_RS14760	COG4771	TonB-dependent receptor
NXX95_RS14770	COG0584	glycerophosphoryl diester phosphodiesterase
NXX95_RS14775	COG0584	glycerophosphoryl diester phosphodiesterase
NXX95_RS14790	COG0745	RESPONSE REGULATOR receiver
NXX95_RS14790	COG2205	protein histidine kinase activity
NXX95_RS14790	COG3292	Two component regulator propeller
NXX95_RS14795	COG4771	TonB-dependent receptor
NXX95_RS14850	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS14855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXX95_RS14930	COG3292	Two component regulator propeller
NXX95_RS14930	COG2205	protein histidine kinase activity
NXX95_RS14930	COG0745	RESPONSE REGULATOR receiver
NXX95_RS14940	COG1595	DNA-templated transcription, initiation
NXX95_RS14945	COG1629	transport
NXX95_RS14950	COG0561	phosphatase activity
NXX95_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS14990	COG2207	Transcriptional regulator
NXX95_RS14990	COG0662	Cupin 2, conserved barrel domain protein
NXX95_RS14995	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS15045	COG1629	transport
NXX95_RS15065	COG3250	beta-galactosidase activity
NXX95_RS15090	COG1629	transport
NXX95_RS15095	COG0702	epimerase
NXX95_RS15115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS15125	COG1253	flavin adenine dinucleotide binding
NXX95_RS15130	COG0501	Belongs to the peptidase M48B family
NXX95_RS15160	COG0482	sulfurtransferase activity
NXX95_RS15175	COG2197	response regulator
NXX95_RS15185	COG1757	Na H antiporter
NXX95_RS15195	COG2814	Major facilitator Superfamily
NXX95_RS15200	COG4953	penicillin-binding protein 1C
NXX95_RS15205	COG2373	Large extracellular alpha-helical protein
NXX95_RS15210	COG0545	Peptidyl-prolyl cis-trans isomerase
NXX95_RS15265	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NXX95_RS15270	COG0646	methionine synthase
NXX95_RS15270	COG1410	methionine synthase
NXX95_RS15275	COG0778	Nitroreductase
NXX95_RS15285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NXX95_RS15290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NXX95_RS15295	COG0572	uridine kinase
NXX95_RS15305	COG4232	protein-disulfide reductase activity
NXX95_RS15320	COG4771	TonB-dependent receptor
NXX95_RS15325	COG0702	epimerase
NXX95_RS15350	COG2271	Major facilitator Superfamily
NXX95_RS15375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NXX95_RS15380	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NXX95_RS15385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NXX95_RS15390	COG0131	Imidazoleglycerol-phosphate dehydratase
NXX95_RS15400	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NXX95_RS15400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX95_RS15455	COG1592	Rubrerythrin
NXX95_RS15455	COG1773	rubredoxin
NXX95_RS15470	COG3118	belongs to the thioredoxin family
NXX95_RS15475	COG3591	Belongs to the peptidase S1B family
NXX95_RS15485	COG0641	radical SAM
NXX95_RS15510	COG0420	3'-5' exonuclease activity
NXX95_RS15530	COG0646	methionine synthase
NXX95_RS15530	COG1410	methionine synthase
NXX95_RS15535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NXX95_RS15540	COG0463	Glycosyl transferase, family 2
NXX95_RS15545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NXX95_RS15560	COG1032	radical SAM domain protein
NXX95_RS15580	COG0363	glucosamine-6-phosphate deaminase activity
NXX95_RS15585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX95_RS15605	COG4974	Belongs to the 'phage' integrase family
NXX95_RS15625	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXX95_RS15665	COG0508	dehydrogenase complex catalyzes the overall conversion of
NXX95_RS15670	COG0022	dehydrogenase e1 component
NXX95_RS15680	COG2264	protein methyltransferase activity
NXX95_RS15700	COG0590	tRNA wobble adenosine to inosine editing
NXX95_RS15705	COG0673	inositol 2-dehydrogenase activity
NXX95_RS15785	COG1501	Belongs to the glycosyl hydrolase 31 family
NXX95_RS15790	COG5012	cobalamin binding
NXX95_RS15805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NXX95_RS15810	COG0698	ribose 5-phosphate isomerase
NXX95_RS15830	COG1070	Carbohydrate kinase
NXX95_RS15835	COG2160	L-arabinose isomerase activity
NXX95_RS15845	COG2816	NAD+ diphosphatase activity
NXX95_RS15865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NXX95_RS15880	COG1482	cell wall glycoprotein biosynthetic process
NXX95_RS15885	COG4974	Belongs to the 'phage' integrase family
NXX95_RS15965	COG0463	Glycosyl transferase, family 2
NXX95_RS15965	COG1216	Glycosyl transferase, family 2
NXX95_RS15985	COG1216	Glycosyl transferase, family 2
NXX95_RS15995	COG1882	Formate acetyltransferase
NXX95_RS16000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NXX95_RS16005	COG0562	UDP-galactopyranose mutase
NXX95_RS16015	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS16030	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS16035	COG0110	maltose O-acetyltransferase activity
NXX95_RS16040	COG0297	glycogen (starch) synthase activity
NXX95_RS16045	COG0110	maltose O-acetyltransferase activity
NXX95_RS16085	COG4221	oxidoreductase activity
NXX95_RS16095	COG1218	3'(2'),5'-bisphosphate nucleotidase
NXX95_RS16100	COG0471	metal ion transport
NXX95_RS16100	COG3273	potassium ion transport
NXX95_RS16105	COG0529	Catalyzes the synthesis of activated sulfate
NXX95_RS16110	COG0175	sulfate reduction
NXX95_RS16115	COG2895	sulfate adenylyltransferase (ATP) activity
NXX95_RS16135	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NXX95_RS16145	COG0242	peptide deformylase activity
NXX95_RS16155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NXX95_RS16160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NXX95_RS16165	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NXX95_RS16170	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NXX95_RS16180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NXX95_RS16185	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXX95_RS16190	COG0674	pyruvate-flavodoxin oxidoreductase activity
NXX95_RS16190	COG1013	pyruvate-flavodoxin oxidoreductase activity
NXX95_RS16190	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NXX95_RS16190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NXX95_RS16200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NXX95_RS16210	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NXX95_RS16225	COG1940	carbohydrate kinase activity
NXX95_RS16250	COG1629	transport
NXX95_RS16315	COG1082	Xylose isomerase domain protein TIM barrel
NXX95_RS16335	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS16370	COG4771	TonB-dependent receptor
NXX95_RS16395	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS16405	COG4771	TonB-dependent receptor
NXX95_RS16410	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS16420	COG0484	heat shock protein binding
NXX95_RS16425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NXX95_RS16430	COG0488	(ABC) transporter
NXX95_RS16460	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS16480	COG2183	response to ionizing radiation
NXX95_RS16485	COG2202	Pas domain
NXX95_RS16485	COG2205	protein histidine kinase activity
NXX95_RS16490	COG0737	Belongs to the 5'-nucleotidase family
NXX95_RS16520	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NXX95_RS16535	COG0490	domain, Protein
NXX95_RS16535	COG2985	domain, Protein
NXX95_RS16540	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NXX95_RS16550	COG1022	Amp-dependent synthetase and ligase
NXX95_RS16555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX95_RS16560	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXX95_RS16565	COG1301	dicarboxylic acid transport
NXX95_RS16570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NXX95_RS16575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NXX95_RS16580	COG0363	glucosamine-6-phosphate deaminase activity
NXX95_RS16585	COG2837	iron assimilation
NXX95_RS16695	COG0629	single-stranded DNA binding
NXX95_RS16715	COG1061	Type III restriction enzyme res subunit
NXX95_RS16740	COG1475	DNA binding
NXX95_RS16810	COG0582	viral genome integration into host DNA
NXX95_RS16850	COG3728	DNA packaging
NXX95_RS16920	COG1595	DNA-templated transcription, initiation
NXX95_RS17015	COG3279	Response regulator of the LytR AlgR family
NXX95_RS17025	COG0577	efflux transmembrane transporter activity
NXX95_RS17025	COG1136	(ABC) transporter
NXX95_RS17030	COG1136	(ABC) transporter
NXX95_RS17050	COG1271	oxidase subunit
NXX95_RS17060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXX95_RS17065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NXX95_RS17090	COG0501	Belongs to the peptidase M48B family
NXX95_RS17095	COG1704	LemA family
NXX95_RS17105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NXX95_RS17110	COG2885	chlorophyll binding
NXX95_RS17115	COG0534	Mate efflux family protein
NXX95_RS17120	COG0657	acetylesterase activity
NXX95_RS17120	COG2755	lipolytic protein G-D-S-L family
NXX95_RS17125	COG0784	Response regulator, receiver
NXX95_RS17125	COG2205	protein histidine kinase activity
NXX95_RS17140	COG4206	TonB-dependent receptor
NXX95_RS17140	COG1629	transport
NXX95_RS17150	COG0784	Response regulator, receiver
NXX95_RS17150	COG2205	protein histidine kinase activity
NXX95_RS17160	COG1368	sulfuric ester hydrolase activity
NXX95_RS17175	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS17185	COG2244	polysaccharide biosynthetic process
NXX95_RS17190	COG1442	glycosyl transferase family 8
NXX95_RS17190	COG1216	Glycosyl transferase, family 2
NXX95_RS17240	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS17255	COG1215	transferase activity, transferring glycosyl groups
NXX95_RS17290	COG1805	sodium ion transport
NXX95_RS17295	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NXX95_RS17310	COG2871	sodium ion transport
NXX95_RS17320	COG0513	Belongs to the DEAD box helicase family
NXX95_RS17325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NXX95_RS17340	COG1739	Uncharacterized protein family UPF0029
NXX95_RS17355	COG0778	Nitroreductase
NXX95_RS17360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXX95_RS17360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NXX95_RS17365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NXX95_RS17370	COG0357	Ribosomal RNA small subunit methyltransferase G
NXX95_RS17385	COG1408	metallophosphoesterase
NXX95_RS17405	COG2217	Heavy metal translocating P-type atpase
NXX95_RS17415	COG0321	lipoyl(octanoyl) transferase activity
NXX95_RS17425	COG2755	lipolytic protein G-D-S-L family
NXX95_RS17425	COG0657	acetylesterase activity
NXX95_RS17445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NXX95_RS17455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NXX95_RS17470	COG1678	Uncharacterized ACR, COG1678
NXX95_RS17485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NXX95_RS17495	COG0305	Participates in initiation and elongation during chromosome replication
NXX95_RS17520	COG3969	phosphoadenosine phosphosulfate
NXX95_RS17525	COG1475	DNA binding
NXX95_RS17585	COG0745	RESPONSE REGULATOR receiver
NXX95_RS17655	COG4206	TonB-dependent receptor
NXX95_RS17655	COG1629	transport
NXX95_RS17665	COG1629	transport
NXX95_RS17665	COG4206	TonB-dependent receptor
NXX95_RS17695	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
NXX95_RS17700	COG3537	Alpha-1,2-mannosidase
NXX95_RS17745	COG3408	Glycogen debranching enzyme
NXX95_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS17770	COG3408	Glycogen debranching enzyme
NXX95_RS17780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NXX95_RS17810	COG3586	endonuclease activity
NXX95_RS17815	COG3586	endonuclease activity
NXX95_RS17835	COG1204	response to ionizing radiation
NXX95_RS17840	COG1204	response to ionizing radiation
NXX95_RS17865	COG4206	TonB-dependent receptor
NXX95_RS17865	COG1629	transport
NXX95_RS17935	COG4232	protein-disulfide reductase activity
NXX95_RS17950	COG3420	alginic acid biosynthetic process
NXX95_RS17975	COG4771	TonB-dependent receptor
NXX95_RS17995	COG3291	Pkd domain containing protein
NXX95_RS18005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXX95_RS18015	COG2731	YhcH YjgK YiaL family protein
NXX95_RS18020	COG2814	Major facilitator Superfamily
NXX95_RS18040	COG3250	beta-galactosidase activity
NXX95_RS18050	COG0784	Response regulator, receiver
NXX95_RS18050	COG2205	protein histidine kinase activity
NXX95_RS18060	COG3250	beta-galactosidase activity
NXX95_RS18065	COG3250	beta-galactosidase activity
NXX95_RS18180	COG3250	beta-galactosidase activity
NXX95_RS18185	COG3292	Two component regulator propeller
NXX95_RS18185	COG2205	protein histidine kinase activity
NXX95_RS18185	COG0745	RESPONSE REGULATOR receiver
NXX95_RS18215	COG2966	Psort location CytoplasmicMembrane, score
NXX95_RS18235	COG0300	oxidoreductase activity
NXX95_RS18240	COG1011	Hydrolase
NXX95_RS18305	COG0745	RESPONSE REGULATOR receiver
NXX95_RS18305	COG2205	protein histidine kinase activity
NXX95_RS18305	COG3292	Two component regulator propeller
NXX95_RS18305	COG0745	RESPONSE REGULATOR receiver
NXX95_RS18305	COG2205	protein histidine kinase activity
NXX95_RS18305	COG3292	Two component regulator propeller
NXX95_RS18345	COG0442	prolyl-tRNA aminoacylation
NXX95_RS18350	COG0745	RESPONSE REGULATOR receiver
NXX95_RS18355	COG2205	protein histidine kinase activity
NXX95_RS18390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NXX95_RS18400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NXX95_RS18405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NXX95_RS18415	COG0552	protein localization to endoplasmic reticulum
NXX95_RS18420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NXX95_RS18435	COG0714	Associated with various cellular activities
NXX95_RS18450	COG2304	oxidoreductase activity
NXX95_RS18495	COG0542	response to heat
NXX95_RS18500	COG0326	Molecular chaperone. Has ATPase activity
NXX95_RS18505	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXX95_RS18525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NXX95_RS18535	COG0336	Belongs to the RNA methyltransferase TrmD family
NXX95_RS18540	COG0167	dihydroorotate dehydrogenase activity
NXX95_RS18545	COG0543	2 iron, 2 sulfur cluster binding
NXX95_RS18560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NXX95_RS18580	COG1538	Outer membrane efflux protein
NXX95_RS18590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NXX95_RS18595	COG1595	DNA-templated transcription, initiation
NXX95_RS18615	COG1132	(ABC) transporter
NXX95_RS18640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NXX95_RS18645	COG1597	lipid kinase activity
NXX95_RS18650	COG0156	8-amino-7-oxononanoate synthase activity
NXX95_RS18660	COG1136	(ABC) transporter
NXX95_RS18660	COG0577	efflux transmembrane transporter activity
NXX95_RS18665	COG1136	(ABC) transporter
NXX95_RS18690	COG3852	Histidine kinase
NXX95_RS18700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NXX95_RS18720	COG0592	DNA-directed DNA polymerase activity
NXX95_RS18745	COG0305	Participates in initiation and elongation during chromosome replication
NXX95_RS18965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NXX95_RS19085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NXX95_RS19090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NXX95_RS19110	COG0560	Phosphoserine phosphatase
NXX95_RS19110	COG3830	Belongs to the UPF0237 family
NXX95_RS19115	COG0513	Belongs to the DEAD box helicase family
NXX95_RS19145	COG0246	Mannitol dehydrogenase
NXX95_RS19150	COG1609	Transcriptional regulator
NXX95_RS19155	COG1904	glucuronate isomerase
NXX95_RS19195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXX95_RS19235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXX95_RS19250	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NXX95_RS19260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NXX95_RS19270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NXX95_RS19270	COG3153	acetyltransferase
NXX95_RS19280	COG0477	Major facilitator Superfamily
NXX95_RS19280	COG2814	Major facilitator Superfamily
NXX95_RS19285	COG2115	Belongs to the xylose isomerase family
NXX95_RS19300	COG0351	phosphomethylpyrimidine kinase
NXX95_RS19305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NXX95_RS19310	COG0045	succinate-CoA ligase (ADP-forming) activity
NXX95_RS19315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NXX95_RS19355	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NXX95_RS19380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NXX95_RS19385	COG2731	YhcH YjgK YiaL family protein
NXX95_RS19395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NXX95_RS19435	COG2205	protein histidine kinase activity
NXX95_RS19440	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NXX95_RS19455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NXX95_RS19465	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NXX95_RS19505	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NXX95_RS19510	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NXX95_RS19515	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS19525	COG1045	serine acetyltransferase
NXX95_RS19540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NXX95_RS19550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NXX95_RS19615	COG0540	Belongs to the ATCase OTCase family
NXX95_RS19620	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NXX95_RS19635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NXX95_RS19640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NXX95_RS19645	COG2985	domain, Protein
NXX95_RS19665	COG1917	Cupin 2, conserved barrel domain protein
NXX95_RS19665	COG2207	Transcriptional regulator
NXX95_RS19670	COG2207	Transcriptional regulator
NXX95_RS19680	COG1690	Belongs to the RtcB family
NXX95_RS19685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NXX95_RS19685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX95_RS19695	COG2431	L-lysine efflux transmembrane transporter activity
NXX95_RS19710	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NXX95_RS19715	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NXX95_RS19720	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX95_RS19725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NXX95_RS19730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX95_RS19735	COG0356	it plays a direct role in the translocation of protons across the membrane
NXX95_RS19745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NXX95_RS19750	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NXX95_RS19755	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NXX95_RS19760	COG0454	-acetyltransferase
NXX95_RS19790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NXX95_RS19800	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NXX95_RS19810	COG0534	Mate efflux family protein
NXX95_RS19820	COG0577	efflux transmembrane transporter activity
NXX95_RS19820	COG1136	(ABC) transporter
NXX95_RS19835	COG2204	response regulator
NXX95_RS19850	COG1151	hydroxylamine reductase activity
NXX95_RS19855	COG2233	PERMEase
NXX95_RS19865	COG1022	Amp-dependent synthetase and ligase
NXX95_RS19870	COG0745	RESPONSE REGULATOR receiver
NXX95_RS19875	COG5002	protein histidine kinase activity
NXX95_RS19895	COG3118	belongs to the thioredoxin family
NXX95_RS19985	COG0681	Belongs to the peptidase S26 family
NXX95_RS20115	COG5002	protein histidine kinase activity
NXX95_RS20125	COG0352	thiamine-phosphate diphosphorylase activity
NXX95_RS20130	COG2022	thiamine diphosphate biosynthetic process
NXX95_RS20135	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NXX95_RS20145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NXX95_RS20150	COG0352	thiamine-phosphate diphosphorylase activity
NXX95_RS20170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NXX95_RS20170	COG0574	Belongs to the PEP-utilizing enzyme family
NXX95_RS20175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXX95_RS20180	COG0564	pseudouridine synthase activity
NXX95_RS20200	COG0024	Methionine aminopeptidase
NXX95_RS20210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NXX95_RS20220	COG0481	GTPase activity
NXX95_RS20240	COG0432	Pfam Uncharacterised protein family UPF0047
NXX95_RS20245	COG0708	Exodeoxyribonuclease III
NXX95_RS20260	COG0217	transcriptional regulatory protein
NXX95_RS20265	COG0072	phenylalanine-tRNA ligase activity
NXX95_RS20265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NXX95_RS20270	COG0305	Participates in initiation and elongation during chromosome replication
NXX95_RS20275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NXX95_RS20280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NXX95_RS20285	COG4657	Part of a membrane complex involved in electron transport
NXX95_RS20290	COG4660	Part of a membrane complex involved in electron transport
NXX95_RS20295	COG4659	FMN binding
NXX95_RS20300	COG4658	electron transport chain
NXX95_RS20305	COG4656	Part of a membrane complex involved in electron transport
NXX95_RS20375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX95_RS20385	COG0438	transferase activity, transferring glycosyl groups
NXX95_RS20440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXX95_RS20460	COG1086	Polysaccharide biosynthesis protein
NXX95_RS20470	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NXX95_RS20500	COG0504	CTP synthase activity
NXX95_RS20505	COG0706	membrane insertase activity
NXX95_RS20510	COG0534	Mate efflux family protein
NXX95_RS20530	COG1983	PspC domain protein
NXX95_RS20550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NXX95_RS20560	COG1388	LysM domain
NXX95_RS20560	COG3942	CHAP domain
NXX95_RS20590	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NXX95_RS20595	COG0556	nucleotide-excision repair
NXX95_RS20610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NXX95_RS20620	COG0842	Transport permease protein
NXX95_RS20625	COG0842	Transport permease protein
NXX95_RS20660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NXX95_RS20665	COG0505	Belongs to the CarA family
NXX95_RS20690	COG0367	asparagine synthase
NXX95_RS20705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NXX95_RS20710	COG0436	Aminotransferase
NXX95_RS20720	COG0347	Belongs to the P(II) protein family
NXX95_RS20725	COG0004	ammonium transporteR
NXX95_RS20760	COG0490	domain, Protein
NXX95_RS20760	COG0471	metal ion transport
NXX95_RS20765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NXX95_RS20765	COG2205	protein histidine kinase activity
NXX95_RS20770	COG1979	alcohol dehydrogenase
NXX95_RS20780	COG0133	tryptophan synthase activity
NXX95_RS20785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NXX95_RS20795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NXX95_RS20800	COG0134	indole-3-glycerol-phosphate synthase activity
NXX95_RS20805	COG0135	phosphoribosylanthranilate isomerase activity
NXX95_RS20810	COG0159	tryptophan synthase activity
NXX95_RS20815	COG0252	asparaginase activity
NXX95_RS20825	COG0745	RESPONSE REGULATOR receiver
NXX95_RS20830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NXX95_RS20855	COG0138	bifunctional purine biosynthesis protein purh
NXX95_RS20870	COG1730	sister chromatid segregation
NXX95_RS20875	COG3487	Iron-regulated protein
NXX95_RS20900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXX95_RS20900	COG1333	cytochrome c biogenesis protein
NXX95_RS20905	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS20940	COG4771	TonB-dependent receptor
NXX95_RS20950	COG4771	TonB-dependent receptor
NXX95_RS20960	COG0490	domain, Protein
NXX95_RS20960	COG2985	domain, Protein
NXX95_RS20965	COG1230	cation diffusion facilitator family transporter
NXX95_RS20985	COG1609	Transcriptional regulator
NXX95_RS20990	COG2721	sulfolactate sulfo-lyase activity
NXX95_RS21005	COG4452	Inner membrane protein CreD
NXX95_RS21040	COG1733	regulation of RNA biosynthetic process
NXX95_RS21060	COG0228	four-way junction DNA binding
NXX95_RS21070	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NXX95_RS21080	COG1070	Carbohydrate kinase
NXX95_RS21090	COG0738	Major facilitator superfamily
NXX95_RS21105	COG2207	Transcriptional regulator
NXX95_RS21110	COG2204	response regulator
NXX95_RS21130	COG1177	transmembrane transport
NXX95_RS21135	COG1176	ABC-type spermidine putrescine transport system, permease component I
NXX95_RS21140	COG3842	ATPase activity
NXX95_RS21145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NXX95_RS21150	COG0058	SHG alpha-glucan phosphorylase activity
NXX95_RS21160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NXX95_RS21180	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NXX95_RS21240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NXX95_RS21245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NXX95_RS21250	COG4948	Mandelate Racemase Muconate Lactonizing
NXX95_RS21265	COG1295	ribonuclease BN
NXX95_RS21270	COG0778	Nitroreductase
NXX95_RS21280	COG0704	Plays a role in the regulation of phosphate uptake
NXX95_RS21285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NXX95_RS21290	COG0581	inorganic phosphate transmembrane transporter activity
NXX95_RS21295	COG0573	inorganic phosphate transmembrane transporter activity
NXX95_RS21315	COG0586	Pfam SNARE associated Golgi protein
NXX95_RS21325	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NXX95_RS21340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NXX95_RS21350	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NXX95_RS21395	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS21440	COG1216	Glycosyl transferase, family 2
NXX95_RS21455	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NXX95_RS21465	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS21500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NXX95_RS21505	COG0497	DNA recombination
NXX95_RS21520	COG0592	DNA-directed DNA polymerase activity
NXX95_RS21540	COG0321	lipoyl(octanoyl) transferase activity
NXX95_RS21540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NXX95_RS21545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NXX95_RS21555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NXX95_RS21560	COG0156	8-amino-7-oxononanoate synthase activity
NXX95_RS21585	COG0019	diaminopimelate decarboxylase activity
NXX95_RS21590	COG0527	aspartate kinase activity
NXX95_RS21595	COG2884	Cell division ATP-binding protein ftsE
NXX95_RS21600	COG0140	phosphoribosyl-ATP diphosphatase activity
NXX95_RS21600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NXX95_RS21605	COG0107	imidazoleglycerol-phosphate synthase activity
NXX95_RS21610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NXX95_RS21615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NXX95_RS21620	COG0788	formyltetrahydrofolate deformylase activity
NXX95_RS21640	COG0693	protein deglycase activity
NXX95_RS21660	COG0534	Mate efflux family protein
NXX95_RS21670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NXX95_RS21685	COG3831	ATPase activity
NXX95_RS21685	COG4884	unkown
NXX95_RS21690	COG2885	chlorophyll binding
NXX95_RS21690	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NXX95_RS21725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NXX95_RS21740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NXX95_RS21745	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NXX95_RS21760	COG0823	Involved in the tonB-independent uptake of proteins
NXX95_RS21760	COG1506	peptidase
NXX95_RS21760	COG4946	Tricorn protease homolog
NXX95_RS21785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NXX95_RS21795	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXX95_RS21810	COG4771	TonB-dependent receptor
NXX95_RS21910	COG0681	Belongs to the peptidase S26 family
NXX95_RS21930	COG3831	ATPase activity
NXX95_RS21930	COG4884	unkown
NXX95_RS21945	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NXX95_RS21950	COG1162	GTPase activity
NXX95_RS21980	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NXX95_RS21985	COG5002	protein histidine kinase activity
NXX95_RS21995	COG1312	Catalyzes the dehydration of D-mannonate
NXX95_RS22000	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS22005	COG1609	Transcriptional regulator
NXX95_RS22020	COG2223	nitrite transmembrane transporter activity
NXX95_RS22030	COG4771	TonB-dependent receptor
NXX95_RS22040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXX95_RS22040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NXX95_RS22055	COG2226	methyltransferase
NXX95_RS22090	COG0511	ligase activity, forming carbon-carbon bonds
NXX95_RS22095	COG0439	Biotin carboxylase
NXX95_RS22100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX95_RS22110	COG1620	l-lactate permease
NXX95_RS22125	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NXX95_RS22140	COG3279	Response regulator of the LytR AlgR family
NXX95_RS22165	COG1472	Belongs to the glycosyl hydrolase 3 family
NXX95_RS22180	COG0702	epimerase
NXX95_RS22185	COG4771	TonB-dependent receptor
NXX95_RS22220	COG0628	permease
NXX95_RS22225	COG1215	transferase activity, transferring glycosyl groups
NXX95_RS22230	COG0456	acetyltransferase
NXX95_RS22235	COG0189	ligase activity
NXX95_RS22235	COG0569	domain protein
NXX95_RS22240	COG0577	efflux transmembrane transporter activity
NXX95_RS22240	COG1136	(ABC) transporter
NXX95_RS22245	COG0436	Aminotransferase
NXX95_RS22260	COG0488	(ABC) transporter
NXX95_RS22275	COG0745	RESPONSE REGULATOR receiver
NXX95_RS22340	COG4206	TonB-dependent receptor
NXX95_RS22355	COG3033	Beta-eliminating lyase
NXX95_RS22380	COG0629	single-stranded DNA binding
NXX95_RS22385	COG1194	a g-specific adenine glycosylase
NXX95_RS22395	COG1530	ribonuclease E activity
NXX95_RS22445	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS22480	COG4771	TonB-dependent receptor
NXX95_RS22485	COG1979	alcohol dehydrogenase
NXX95_RS22500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NXX95_RS22510	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NXX95_RS22525	COG4191	Histidine kinase
NXX95_RS22530	COG2204	response regulator
NXX95_RS22550	COG0577	efflux transmembrane transporter activity
NXX95_RS22560	COG1136	(ABC) transporter
NXX95_RS22570	COG1252	NADH dehydrogenase
NXX95_RS22575	COG1705	Flagellar rod assembly protein muramidase FlgJ
NXX95_RS22580	COG0295	cytidine deaminase activity
NXX95_RS22590	COG3059	membrane
NXX95_RS22595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NXX95_RS22615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NXX95_RS22635	COG4206	TonB-dependent receptor
NXX95_RS22635	COG1629	transport
NXX95_RS22655	COG0686	Belongs to the AlaDH PNT family
NXX95_RS22695	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NXX95_RS22715	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NXX95_RS22720	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NXX95_RS22735	COG1595	DNA-templated transcription, initiation
NXX95_RS22750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NXX95_RS22755	COG1741	Belongs to the pirin family
NXX95_RS22760	COG0259	pyridoxamine-phosphate oxidase activity
NXX95_RS22775	COG0346	lactoylglutathione lyase activity
NXX95_RS22915	COG3177	Filamentation induced by cAMP protein fic
NXX95_RS22920	COG1396	sequence-specific DNA binding
NXX95_RS22960	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NXX95_RS22960	COG1918	ferrous iron import across plasma membrane
NXX95_RS22965	COG0037	tRNA processing
NXX95_RS22980	COG3119	arylsulfatase activity
NXX95_RS22985	COG0534	Mate efflux family protein
NXX95_RS22990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NXX95_RS22995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NXX95_RS23040	COG2003	Belongs to the UPF0758 family
NXX95_RS23105	COG1983	PspC domain protein
NXX95_RS23110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NXX95_RS23135	COG2195	Cleaves the N-terminal amino acid of tripeptides
NXX95_RS23150	COG0668	transmembrane transport
NXX95_RS23160	COG3250	beta-galactosidase activity
NXX95_RS23165	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS23185	COG4206	TonB-dependent receptor
NXX95_RS23185	COG1629	transport
NXX95_RS23205	COG4974	Belongs to the 'phage' integrase family
NXX95_RS23245	COG0210	DNA helicase
NXX95_RS23250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NXX95_RS23260	COG3292	Two component regulator propeller
NXX95_RS23260	COG2205	protein histidine kinase activity
NXX95_RS23260	COG3292	Two component regulator propeller
NXX95_RS23260	COG2205	protein histidine kinase activity
NXX95_RS23260	COG0745	RESPONSE REGULATOR receiver
NXX95_RS23260	COG0745	RESPONSE REGULATOR receiver
NXX95_RS23265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NXX95_RS23270	COG1830	Aldolase
NXX95_RS23275	COG0588	phosphoglycerate mutase activity
NXX95_RS23290	COG4206	TonB-dependent receptor
NXX95_RS23290	COG1629	transport
NXX95_RS23305	COG1119	ATPase activity
NXX95_RS23310	COG3661	Belongs to the glycosyl hydrolase 67 family
NXX95_RS23325	COG2211	Major facilitator Superfamily
NXX95_RS23335	COG1523	belongs to the glycosyl hydrolase 13 family
NXX95_RS23340	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NXX95_RS23490	COG4974	Belongs to the 'phage' integrase family
NXX95_RS23500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NXX95_RS23505	COG2814	Major facilitator Superfamily
NXX95_RS23510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NXX95_RS23515	COG0126	phosphoglycerate kinase activity
NXX95_RS23530	COG2311	Membrane
NXX95_RS23540	COG0424	maF-like protein
NXX95_RS23560	COG0778	Nitroreductase
NXX95_RS23570	COG0288	reversible hydration of carbon dioxide
NXX95_RS23585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX95_RS23595	COG0511	ligase activity, forming carbon-carbon bonds
NXX95_RS23600	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXX95_RS23605	COG0191	fructose-bisphosphate aldolase activity
NXX95_RS23610	COG0254	rRNA binding
NXX95_RS23615	COG1373	ATPase (AAA superfamily
NXX95_RS23665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX95_RS23670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXX95_RS23690	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NXX95_RS23715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NXX95_RS23730	COG1280	lysine exporter protein (LysE YggA)
NXX95_RS23740	COG0745	RESPONSE REGULATOR receiver
NXX95_RS23740	COG0745	RESPONSE REGULATOR receiver
NXX95_RS23740	COG3292	Two component regulator propeller
NXX95_RS23740	COG2205	protein histidine kinase activity
NXX95_RS23740	COG3292	Two component regulator propeller
NXX95_RS23740	COG2205	protein histidine kinase activity
NXX95_RS23755	COG1649	PFAM Uncharacterised BCR, COG1649
NXX95_RS23780	COG1649	PFAM Uncharacterised BCR, COG1649
NXX95_RS23810	COG2113	Glycine betaine
NXX95_RS23815	COG4176	ABC-type proline glycine betaine transport system permease component
NXX95_RS23825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NXX95_RS23835	COG3292	Two component regulator propeller
NXX95_RS23835	COG0745	RESPONSE REGULATOR receiver
NXX95_RS23835	COG2205	protein histidine kinase activity
NXX95_RS23850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NXX95_RS23850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NXX95_RS23860	COG1621	beta-fructofuranosidase activity
NXX95_RS23880	COG1629	transport
NXX95_RS23890	COG1621	beta-fructofuranosidase activity
NXX95_RS23900	COG1752	Esterase of the alpha-beta hydrolase superfamily
NXX95_RS23905	COG0475	glutathione-regulated potassium exporter activity
NXX95_RS23945	COG2205	protein histidine kinase activity
NXX95_RS23945	COG2202	Pas domain
NXX95_RS23955	COG2205	protein histidine kinase activity
NXX95_RS23955	COG2202	Pas domain
NXX95_RS23960	COG5002	protein histidine kinase activity
NXX95_RS23990	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NXX95_RS23995	COG1960	acyl-CoA dehydrogenase activity
NXX95_RS24000	COG0705	Rhomboid family
NXX95_RS24015	COG1956	GAF domain-containing protein
NXX95_RS24025	COG0484	heat shock protein binding
NXX95_RS24050	COG0028	Belongs to the TPP enzyme family
NXX95_RS24080	COG4974	Belongs to the 'phage' integrase family
NXX95_RS24085	COG4974	Belongs to the 'phage' integrase family
NXX95_RS24150	COG1629	transport
NXX95_RS24160	COG1192	Involved in chromosome partitioning
NXX95_RS24180	COG1120	ATPase activity
NXX95_RS24185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXX95_RS24230	COG0459	protein refolding
NXX95_RS24235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NXX95_RS24270	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NXX95_RS24280	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NXX95_RS24285	COG0124	histidyl-tRNA synthetase
NXX95_RS24300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NXX95_RS24325	COG0514	ATP-dependent DNA helicase (RecQ)
NXX95_RS24335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NXX95_RS24340	COG1368	sulfuric ester hydrolase activity
NXX95_RS24345	COG0671	phosphoesterase, PA-phosphatase related
NXX95_RS24350	COG0473	3-isopropylmalate dehydrogenase activity
NXX95_RS24360	COG0066	3-isopropylmalate dehydratase activity
NXX95_RS24365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXX95_RS24370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NXX95_RS24430	COG1917	Cupin 2, conserved barrel domain protein
NXX95_RS24430	COG4977	sequence-specific DNA binding
NXX95_RS24455	COG1028	Short-chain dehydrogenase reductase Sdr
NXX95_RS24465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NXX95_RS24470	COG3118	belongs to the thioredoxin family
NXX95_RS24480	COG0439	Biotin carboxylase
NXX95_RS24490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NXX95_RS24500	COG2873	o-acetylhomoserine
NXX95_RS24560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NXX95_RS24565	COG1088	dTDP-glucose 4,6-dehydratase activity
NXX95_RS24570	COG1575	Belongs to the MenA family. Type 1 subfamily
NXX95_RS24575	COG1408	metallophosphoesterase
NXX95_RS24585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NXX95_RS24590	COG0194	GDP metabolic process
NXX95_RS24610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NXX95_RS24615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NXX95_RS24625	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NXX95_RS24630	COG0750	zinc metalloprotease
NXX95_RS24640	COG2814	Major facilitator Superfamily
NXX95_RS24650	COG1328	CTP reductase activity
NXX95_RS24710	COG1629	transport
NXX95_RS24710	COG4206	TonB-dependent receptor
NXX95_RS24735	COG3023	N-Acetylmuramoyl-L-alanine amidase
NXX95_RS24765	COG1538	Outer membrane efflux protein
NXX95_RS24810	COG3525	Glycosyl hydrolase, family 20, catalytic domain
NXX95_RS24825	COG0561	phosphatase activity
NXX95_RS24830	COG4771	TonB-dependent receptor
NXX95_RS24855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NXX95_RS24915	COG1505	serine-type exopeptidase activity
NXX95_RS24930	COG3119	arylsulfatase activity
NXX95_RS24935	COG3119	arylsulfatase activity
NXX95_RS24940	COG0617	tRNA 3'-terminal CCA addition
NXX95_RS24955	COG0632	four-way junction helicase activity
NXX95_RS24960	COG0673	inositol 2-dehydrogenase activity
NXX95_RS24965	COG1272	protein, Hemolysin III
NXX95_RS24970	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NXX95_RS24975	COG1629	transport
NXX95_RS24975	COG4206	TonB-dependent receptor
NXX95_RS24990	COG2204	response regulator
NXX95_RS24995	COG0488	(ABC) transporter
NXX95_RS25045	COG1595	DNA-templated transcription, initiation
NXX95_RS25055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NXX95_RS25060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NXX95_RS25070	COG1522	sequence-specific DNA binding
NXX95_RS25100	COG0811	peptide transport
NXX95_RS25110	COG0084	hydrolase, TatD family'
NXX95_RS25130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NXX95_RS25135	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NXX95_RS25140	COG0205	6-phosphofructokinase activity
NXX95_RS25185	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NXX95_RS25190	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NXX95_RS25200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NXX95_RS25215	COG0028	Belongs to the TPP enzyme family
NXX95_RS25220	COG0129	dihydroxy-acid dehydratase activity
NXX95_RS25230	COG3681	Belongs to the UPF0597 family
NXX95_RS25250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NXX95_RS25325	COG1595	DNA-templated transcription, initiation
NXX95_RS25330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX95_RS25330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX95_RS25335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
NXX95_RS25340	COG0569	domain protein
NXX95_RS25340	COG2985	domain, Protein
NXX95_RS25380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NXX95_RS25415	COG0702	epimerase
NXX95_RS25420	COG4206	TonB-dependent receptor
NXX95_RS25420	COG1629	transport
NXX95_RS25425	COG1940	carbohydrate kinase activity
NXX95_RS25435	COG2188	Transcriptional regulator
NXX95_RS25495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NXX95_RS25505	COG2207	Transcriptional regulator
NXX95_RS25505	COG1609	Transcriptional regulator
NXX95_RS25510	COG0534	Mate efflux family protein
NXX95_RS25515	COG4974	Belongs to the 'phage' integrase family
NXX95_RS25550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NXX95_RS25550	COG0551	DNA topoisomerase type I activity
NXX95_RS25580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NXX95_RS25600	COG0577	efflux transmembrane transporter activity
NXX95_RS25725	COG0358	DNA primase activity
NXX95_RS25795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NXX95_RS25800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NXX95_RS25805	COG0166	Belongs to the GPI family
NXX95_RS25820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NXX95_RS25845	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NXX95_RS25860	COG3876	Protein conserved in bacteria
NXX95_RS25885	COG2315	Protein conserved in bacteria
NXX95_RS25915	COG0860	N-Acetylmuramoyl-L-alanine amidase