locus-tag	class	description
INE92_RS00025	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INE92_RS00070	COG0525	valine-tRNA ligase activity
INE92_RS00075	COG0784	Response regulator, receiver
INE92_RS00075	COG2205	protein histidine kinase activity
INE92_RS00075	COG5002	protein histidine kinase activity
INE92_RS00090	COG1629	transport
INE92_RS00090	COG4206	TonB-dependent receptor
INE92_RS00095	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE92_RS00120	COG0653	protein targeting
INE92_RS00125	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
INE92_RS00135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
INE92_RS00155	COG1253	flavin adenine dinucleotide binding
INE92_RS00160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INE92_RS00170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
INE92_RS00180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
INE92_RS00185	COG2204	response regulator
INE92_RS00225	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
INE92_RS00225	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
INE92_RS00240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
INE92_RS00245	COG0563	adenylate kinase activity
INE92_RS00250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INE92_RS00255	COG1496	oxidoreductase activity
INE92_RS00270	COG2706	6-phosphogluconolactonase activity
INE92_RS00280	COG4804	nuclease activity
INE92_RS00320	COG3142	Participates in the control of copper homeostasis
INE92_RS00325	COG1418	mRNA catabolic process
INE92_RS00365	COG4771	TonB-dependent receptor
INE92_RS00370	COG0702	epimerase
INE92_RS00400	COG0246	Mannitol dehydrogenase
INE92_RS00410	COG1063	alcohol dehydrogenase
INE92_RS00425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INE92_RS00430	COG2832	Protein of unknown function (DUF454)
INE92_RS00440	COG0602	queuosine metabolic process
INE92_RS00445	COG0247	lactate metabolic process
INE92_RS00450	COG1139	Iron-sulfur cluster binding protein
INE92_RS00460	COG0351	phosphomethylpyrimidine kinase
INE92_RS00480	COG4589	Belongs to the CDS family
INE92_RS00490	COG2304	oxidoreductase activity
INE92_RS00510	COG1393	Belongs to the ArsC family
INE92_RS00520	COG4771	TonB-dependent receptor
INE92_RS00535	COG2233	PERMEase
INE92_RS00540	COG1509	lysine 2,3-aminomutase activity
INE92_RS00550	COG1115	amino acid carrier protein
INE92_RS00585	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS00595	COG0776	regulation of translation
INE92_RS00635	COG1285	pathogenesis
INE92_RS00645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
INE92_RS00650	COG0741	lytic transglycosylase activity
INE92_RS00650	COG1388	LysM domain
INE92_RS00700	COG0534	Mate efflux family protein
INE92_RS00705	COG0564	pseudouridine synthase activity
INE92_RS00735	COG0346	lactoylglutathione lyase activity
INE92_RS00785	COG1396	sequence-specific DNA binding
INE92_RS00800	COG0582	viral genome integration into host DNA
INE92_RS00835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
INE92_RS00850	COG1063	alcohol dehydrogenase
INE92_RS00870	COG0653	protein targeting
INE92_RS00895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
INE92_RS00910	COG3645	SOS response
INE92_RS00935	COG0582	viral genome integration into host DNA
INE92_RS00975	COG4974	Belongs to the 'phage' integrase family
INE92_RS00985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
INE92_RS00990	COG2205	protein histidine kinase activity
INE92_RS00990	COG0784	Response regulator, receiver
INE92_RS00995	COG0702	epimerase
INE92_RS01005	COG4864	UPF0365 protein
INE92_RS01020	COG0037	tRNA processing
INE92_RS01030	COG1477	protein flavinylation
INE92_RS01035	COG1971	Probably functions as a manganese efflux pump
INE92_RS01050	COG0463	Glycosyl transferase, family 2
INE92_RS01070	COG0148	phosphopyruvate hydratase activity
INE92_RS01080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
INE92_RS01085	COG1082	Xylose isomerase domain protein TIM barrel
INE92_RS01090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
INE92_RS01095	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE92_RS01100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
INE92_RS01105	COG4651	solute:proton antiporter activity
INE92_RS01105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INE92_RS01115	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INE92_RS01120	COG0193	aminoacyl-tRNA hydrolase activity
INE92_RS01125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
INE92_RS01135	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INE92_RS01150	COG0237	dephospho-CoA kinase activity
INE92_RS01165	COG0542	response to heat
INE92_RS01180	COG0583	DNA-binding transcription factor activity
INE92_RS01255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE92_RS01260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INE92_RS01270	COG1373	ATPase (AAA superfamily
INE92_RS01275	COG3304	Inner membrane component domain
INE92_RS01280	COG2855	membrane
INE92_RS01285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
INE92_RS01290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
INE92_RS01310	COG0443	Heat shock 70 kDa protein
INE92_RS01515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
INE92_RS01515	COG0456	acetyltransferase
INE92_RS01535	COG5433	transposase activity
INE92_RS01555	COG1538	Outer membrane efflux protein
INE92_RS01585	COG0739	heme binding
INE92_RS01645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE92_RS01650	COG1705	Flagellar rod assembly protein muramidase FlgJ
INE92_RS01680	COG1373	ATPase (AAA superfamily
INE92_RS01735	COG3118	belongs to the thioredoxin family
INE92_RS01795	COG1192	Involved in chromosome partitioning
INE92_RS01800	COG0629	single-stranded DNA binding
INE92_RS01905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
INE92_RS01920	COG4651	solute:proton antiporter activity
INE92_RS01920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INE92_RS01925	COG0306	phosphate transporter
INE92_RS01935	COG0586	Pfam SNARE associated Golgi protein
INE92_RS01995	COG0038	chloride channel
INE92_RS02000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
INE92_RS02015	COG1940	carbohydrate kinase activity
INE92_RS02025	COG3119	arylsulfatase activity
INE92_RS02035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS02040	COG0702	epimerase
INE92_RS02045	COG4771	TonB-dependent receptor
INE92_RS02055	COG5434	Belongs to the glycosyl hydrolase 28 family
INE92_RS02060	COG0745	RESPONSE REGULATOR receiver
INE92_RS02060	COG2205	protein histidine kinase activity
INE92_RS02060	COG3292	Two component regulator propeller
INE92_RS02065	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
INE92_RS02070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INE92_RS02080	COG3250	beta-galactosidase activity
INE92_RS02095	COG4974	Belongs to the 'phage' integrase family
INE92_RS02125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INE92_RS02165	COG3754	Rhamnan synthesis protein F
INE92_RS02190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INE92_RS02210	COG1760	l-serine dehydratase
INE92_RS02215	COG0598	Magnesium transport protein CorA
INE92_RS02220	COG1193	negative regulation of DNA recombination
INE92_RS02235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INE92_RS02245	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
INE92_RS02250	COG0456	acetyltransferase
INE92_RS02260	COG3189	MarR family transcriptional regulator
INE92_RS02265	COG0561	phosphatase activity
INE92_RS02270	COG1169	isochorismate synthase
INE92_RS02275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
INE92_RS02280	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
INE92_RS02285	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS02295	COG1191	sigma factor activity
INE92_RS02310	COG4206	TonB-dependent receptor
INE92_RS02310	COG1629	transport
INE92_RS02330	COG0783	Belongs to the Dps family
INE92_RS02335	COG0583	DNA-binding transcription factor activity
INE92_RS02345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INE92_RS02365	COG1595	DNA-templated transcription, initiation
INE92_RS02380	COG4771	TonB-dependent receptor
INE92_RS02390	COG0584	glycerophosphoryl diester phosphodiesterase
INE92_RS02395	COG0584	glycerophosphoryl diester phosphodiesterase
INE92_RS02420	COG4771	TonB-dependent receptor
INE92_RS02425	COG0702	epimerase
INE92_RS02435	COG0584	glycerophosphoryl diester phosphodiesterase
INE92_RS02440	COG2271	Major facilitator Superfamily
INE92_RS02460	COG4680	protein conserved in bacteria
INE92_RS02490	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS02495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INE92_RS02500	COG1882	Formate acetyltransferase
INE92_RS02510	COG4974	Belongs to the 'phage' integrase family
INE92_RS02655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INE92_RS02655	COG0551	DNA topoisomerase type I activity
INE92_RS02715	COG4974	Belongs to the 'phage' integrase family
INE92_RS02720	COG1309	transcriptional regulator
INE92_RS02780	COG4804	nuclease activity
INE92_RS02850	COG0745	RESPONSE REGULATOR receiver
INE92_RS02850	COG3292	Two component regulator propeller
INE92_RS02850	COG2205	protein histidine kinase activity
INE92_RS02860	COG1595	DNA-templated transcription, initiation
INE92_RS02865	COG4771	TonB-dependent receptor
INE92_RS02870	COG0561	phosphatase activity
INE92_RS02905	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS02910	COG0662	Cupin 2, conserved barrel domain protein
INE92_RS02910	COG2207	Transcriptional regulator
INE92_RS02915	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS02940	COG2267	carboxylic ester hydrolase activity
INE92_RS02960	COG1629	transport
INE92_RS02960	COG4206	TonB-dependent receptor
INE92_RS02985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS02995	COG1253	flavin adenine dinucleotide binding
INE92_RS03000	COG0501	Belongs to the peptidase M48B family
INE92_RS03030	COG0482	sulfurtransferase activity
INE92_RS03045	COG2197	response regulator
INE92_RS03055	COG1757	Na H antiporter
INE92_RS03065	COG2814	Major facilitator Superfamily
INE92_RS03070	COG4953	penicillin-binding protein 1C
INE92_RS03075	COG2373	Large extracellular alpha-helical protein
INE92_RS03080	COG0545	Peptidyl-prolyl cis-trans isomerase
INE92_RS03140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
INE92_RS03145	COG1410	methionine synthase
INE92_RS03145	COG0646	methionine synthase
INE92_RS03150	COG0778	Nitroreductase
INE92_RS03155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE92_RS03160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
INE92_RS03165	COG0572	uridine kinase
INE92_RS03175	COG4232	protein-disulfide reductase activity
INE92_RS03190	COG4771	TonB-dependent receptor
INE92_RS03195	COG0702	epimerase
INE92_RS03220	COG2271	Major facilitator Superfamily
INE92_RS03240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
INE92_RS03245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
INE92_RS03250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
INE92_RS03255	COG0131	Imidazoleglycerol-phosphate dehydratase
INE92_RS03265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE92_RS03265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
INE92_RS03335	COG1592	Rubrerythrin
INE92_RS03335	COG1773	rubredoxin
INE92_RS03350	COG3118	belongs to the thioredoxin family
INE92_RS03365	COG3591	Belongs to the peptidase S1B family
INE92_RS03370	COG3591	Belongs to the peptidase S1B family
INE92_RS03375	COG0641	radical SAM
INE92_RS03400	COG0420	3'-5' exonuclease activity
INE92_RS03420	COG1410	methionine synthase
INE92_RS03420	COG0646	methionine synthase
INE92_RS03425	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
INE92_RS03430	COG0463	Glycosyl transferase, family 2
INE92_RS03465	COG0582	viral genome integration into host DNA
INE92_RS03530	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INE92_RS03545	COG1032	radical SAM domain protein
INE92_RS03565	COG0363	glucosamine-6-phosphate deaminase activity
INE92_RS03570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE92_RS03590	COG4974	Belongs to the 'phage' integrase family
INE92_RS03610	COG1752	Esterase of the alpha-beta hydrolase superfamily
INE92_RS03650	COG0508	dehydrogenase complex catalyzes the overall conversion of
INE92_RS03655	COG0022	dehydrogenase e1 component
INE92_RS03665	COG2264	protein methyltransferase activity
INE92_RS03685	COG0590	tRNA wobble adenosine to inosine editing
INE92_RS03690	COG0673	inositol 2-dehydrogenase activity
INE92_RS03695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
INE92_RS03775	COG1501	Belongs to the glycosyl hydrolase 31 family
INE92_RS03780	COG5012	cobalamin binding
INE92_RS03795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
INE92_RS03800	COG0698	ribose 5-phosphate isomerase
INE92_RS03805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INE92_RS03820	COG1070	Carbohydrate kinase
INE92_RS03825	COG2160	L-arabinose isomerase activity
INE92_RS03835	COG2816	NAD+ diphosphatase activity
INE92_RS03855	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
INE92_RS03870	COG1482	cell wall glycoprotein biosynthetic process
INE92_RS03890	COG4974	Belongs to the 'phage' integrase family
INE92_RS03995	COG1216	Glycosyl transferase, family 2
INE92_RS04005	COG1882	Formate acetyltransferase
INE92_RS04010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INE92_RS04015	COG0562	UDP-galactopyranose mutase
INE92_RS04020	COG0438	transferase activity, transferring glycosyl groups
INE92_RS04035	COG0438	transferase activity, transferring glycosyl groups
INE92_RS04040	COG0110	maltose O-acetyltransferase activity
INE92_RS04045	COG0297	glycogen (starch) synthase activity
INE92_RS04050	COG0110	maltose O-acetyltransferase activity
INE92_RS04095	COG4221	oxidoreductase activity
INE92_RS04105	COG1218	3'(2'),5'-bisphosphate nucleotidase
INE92_RS04110	COG0471	metal ion transport
INE92_RS04110	COG3273	potassium ion transport
INE92_RS04115	COG0529	Catalyzes the synthesis of activated sulfate
INE92_RS04120	COG0175	sulfate reduction
INE92_RS04125	COG2895	sulfate adenylyltransferase (ATP) activity
INE92_RS04150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
INE92_RS04155	COG0242	peptide deformylase activity
INE92_RS04165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
INE92_RS04170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
INE92_RS04175	COG0291	Belongs to the bacterial ribosomal protein bL35 family
INE92_RS04180	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
INE92_RS04190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INE92_RS04195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
INE92_RS04200	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
INE92_RS04200	COG0674	pyruvate-flavodoxin oxidoreductase activity
INE92_RS04200	COG1013	pyruvate-flavodoxin oxidoreductase activity
INE92_RS04200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INE92_RS04210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
INE92_RS04220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
INE92_RS04235	COG1940	carbohydrate kinase activity
INE92_RS04250	COG2814	Major facilitator Superfamily
INE92_RS04270	COG1629	transport
INE92_RS04275	COG0561	phosphatase activity
INE92_RS04300	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS04345	COG1629	transport
INE92_RS04370	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS04375	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS04380	COG4771	TonB-dependent receptor
INE92_RS04385	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE92_RS04390	COG4335	DNA alkylation repair
INE92_RS04395	COG0484	heat shock protein binding
INE92_RS04400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
INE92_RS04405	COG0488	(ABC) transporter
INE92_RS04435	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS04495	COG2183	response to ionizing radiation
INE92_RS04500	COG2202	Pas domain
INE92_RS04500	COG2205	protein histidine kinase activity
INE92_RS04505	COG0737	Belongs to the 5'-nucleotidase family
INE92_RS04540	COG2425	protein containing a von Willebrand factor type A (vWA) domain
INE92_RS04555	COG0490	domain, Protein
INE92_RS04555	COG2985	domain, Protein
INE92_RS04560	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
INE92_RS04575	COG1022	Amp-dependent synthetase and ligase
INE92_RS04580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE92_RS04585	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
INE92_RS04590	COG1301	dicarboxylic acid transport
INE92_RS04595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
INE92_RS04600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
INE92_RS04605	COG0363	glucosamine-6-phosphate deaminase activity
INE92_RS04610	COG2837	iron assimilation
INE92_RS04620	COG3279	Response regulator of the LytR AlgR family
INE92_RS04630	COG0577	efflux transmembrane transporter activity
INE92_RS04630	COG1136	(ABC) transporter
INE92_RS04635	COG1136	(ABC) transporter
INE92_RS04640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE92_RS04655	COG1271	oxidase subunit
INE92_RS04665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INE92_RS04670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INE92_RS04695	COG0501	Belongs to the peptidase M48B family
INE92_RS04700	COG1704	LemA family
INE92_RS04710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INE92_RS04715	COG2885	chlorophyll binding
INE92_RS04720	COG0534	Mate efflux family protein
INE92_RS04725	COG0657	acetylesterase activity
INE92_RS04725	COG2755	lipolytic protein G-D-S-L family
INE92_RS04730	COG0784	Response regulator, receiver
INE92_RS04730	COG2205	protein histidine kinase activity
INE92_RS04740	COG0488	(ABC) transporter
INE92_RS04745	COG1629	transport
INE92_RS04745	COG4206	TonB-dependent receptor
INE92_RS04755	COG2205	protein histidine kinase activity
INE92_RS04755	COG0784	Response regulator, receiver
INE92_RS04765	COG1368	sulfuric ester hydrolase activity
INE92_RS04780	COG0438	transferase activity, transferring glycosyl groups
INE92_RS04790	COG2244	polysaccharide biosynthetic process
INE92_RS04795	COG1442	glycosyl transferase family 8
INE92_RS04795	COG1216	Glycosyl transferase, family 2
INE92_RS04840	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS04855	COG1215	transferase activity, transferring glycosyl groups
INE92_RS04890	COG1805	sodium ion transport
INE92_RS04895	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
INE92_RS04910	COG2871	sodium ion transport
INE92_RS04925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
INE92_RS04930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INE92_RS04940	COG1739	Uncharacterized protein family UPF0029
INE92_RS04955	COG0778	Nitroreductase
INE92_RS04960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
INE92_RS04960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
INE92_RS04965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INE92_RS04970	COG0357	Ribosomal RNA small subunit methyltransferase G
INE92_RS04985	COG1408	metallophosphoesterase
INE92_RS05005	COG2217	Heavy metal translocating P-type atpase
INE92_RS05015	COG0321	lipoyl(octanoyl) transferase activity
INE92_RS05025	COG2755	lipolytic protein G-D-S-L family
INE92_RS05025	COG0657	acetylesterase activity
INE92_RS05045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
INE92_RS05055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
INE92_RS05070	COG1678	Uncharacterized ACR, COG1678
INE92_RS05085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INE92_RS05110	COG3969	phosphoadenosine phosphosulfate
INE92_RS05115	COG1475	DNA binding
INE92_RS05175	COG0745	RESPONSE REGULATOR receiver
INE92_RS05240	COG4771	TonB-dependent receptor
INE92_RS05250	COG4771	TonB-dependent receptor
INE92_RS05285	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE92_RS05290	COG3537	Alpha-1,2-mannosidase
INE92_RS05305	COG1629	transport
INE92_RS05305	COG4206	TonB-dependent receptor
INE92_RS05310	COG0702	epimerase
INE92_RS05340	COG3408	Glycogen debranching enzyme
INE92_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS05365	COG3408	Glycogen debranching enzyme
INE92_RS05375	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS05440	COG4206	TonB-dependent receptor
INE92_RS05440	COG1629	transport
INE92_RS05500	COG4232	protein-disulfide reductase activity
INE92_RS05515	COG3420	alginic acid biosynthetic process
INE92_RS05540	COG4771	TonB-dependent receptor
INE92_RS05560	COG3291	Pkd domain containing protein
INE92_RS05570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INE92_RS05580	COG2731	YhcH YjgK YiaL family protein
INE92_RS05585	COG2814	Major facilitator Superfamily
INE92_RS05595	COG2205	protein histidine kinase activity
INE92_RS05595	COG0784	Response regulator, receiver
INE92_RS05605	COG3250	beta-galactosidase activity
INE92_RS05615	COG0784	Response regulator, receiver
INE92_RS05615	COG2205	protein histidine kinase activity
INE92_RS05625	COG3250	beta-galactosidase activity
INE92_RS05630	COG3250	beta-galactosidase activity
INE92_RS05635	COG0745	RESPONSE REGULATOR receiver
INE92_RS05640	COG5002	protein histidine kinase activity
INE92_RS05750	COG3250	beta-galactosidase activity
INE92_RS05755	COG3292	Two component regulator propeller
INE92_RS05755	COG0745	RESPONSE REGULATOR receiver
INE92_RS05755	COG2205	protein histidine kinase activity
INE92_RS05785	COG2966	Psort location CytoplasmicMembrane, score
INE92_RS05800	COG0300	oxidoreductase activity
INE92_RS05805	COG1011	Hydrolase
INE92_RS05870	COG2205	protein histidine kinase activity
INE92_RS05870	COG0745	RESPONSE REGULATOR receiver
INE92_RS05870	COG0745	RESPONSE REGULATOR receiver
INE92_RS05870	COG3292	Two component regulator propeller
INE92_RS05870	COG3292	Two component regulator propeller
INE92_RS05870	COG2205	protein histidine kinase activity
INE92_RS05910	COG0442	prolyl-tRNA aminoacylation
INE92_RS05915	COG0745	RESPONSE REGULATOR receiver
INE92_RS05920	COG2205	protein histidine kinase activity
INE92_RS05955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
INE92_RS05965	COG0227	Belongs to the bacterial ribosomal protein bL28 family
INE92_RS05970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INE92_RS05980	COG0552	protein localization to endoplasmic reticulum
INE92_RS05985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE92_RS06000	COG0714	Associated with various cellular activities
INE92_RS06015	COG2304	oxidoreductase activity
INE92_RS06055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INE92_RS06060	COG0542	response to heat
INE92_RS06065	COG0326	Molecular chaperone. Has ATPase activity
INE92_RS06070	COG1752	Esterase of the alpha-beta hydrolase superfamily
INE92_RS06130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INE92_RS06135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
INE92_RS06140	COG0336	Belongs to the RNA methyltransferase TrmD family
INE92_RS06150	COG0167	dihydroorotate dehydrogenase activity
INE92_RS06155	COG0543	2 iron, 2 sulfur cluster binding
INE92_RS06170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INE92_RS06185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE92_RS06190	COG1538	Outer membrane efflux protein
INE92_RS06200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
INE92_RS06205	COG1595	DNA-templated transcription, initiation
INE92_RS06230	COG4988	ABC transporter
INE92_RS06270	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INE92_RS06320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
INE92_RS06325	COG1597	lipid kinase activity
INE92_RS06330	COG0156	8-amino-7-oxononanoate synthase activity
INE92_RS06345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
INE92_RS06480	COG2433	Pfam Transposase IS66
INE92_RS06485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
INE92_RS06490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
INE92_RS06510	COG0560	Phosphoserine phosphatase
INE92_RS06510	COG3830	Belongs to the UPF0237 family
INE92_RS06515	COG0513	Belongs to the DEAD box helicase family
INE92_RS06550	COG0246	Mannitol dehydrogenase
INE92_RS06555	COG1609	Transcriptional regulator
INE92_RS06560	COG1904	glucuronate isomerase
INE92_RS06570	COG3392	D12 class N6 adenine-specific DNA methyltransferase
INE92_RS06670	COG0740	serine-type endopeptidase activity
INE92_RS06825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INE92_RS06865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INE92_RS06880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
INE92_RS06890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
INE92_RS06900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INE92_RS06900	COG3153	acetyltransferase
INE92_RS06935	COG0477	Major facilitator Superfamily
INE92_RS06935	COG2814	Major facilitator Superfamily
INE92_RS06940	COG2115	Belongs to the xylose isomerase family
INE92_RS06955	COG0351	phosphomethylpyrimidine kinase
INE92_RS06960	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INE92_RS06965	COG0045	succinate-CoA ligase (ADP-forming) activity
INE92_RS06970	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INE92_RS07005	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
INE92_RS07010	COG0348	domain, Protein
INE92_RS07030	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
INE92_RS07035	COG2731	YhcH YjgK YiaL family protein
INE92_RS07045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INE92_RS07325	COG2205	protein histidine kinase activity
INE92_RS07330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INE92_RS07350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
INE92_RS07360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
INE92_RS07395	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
INE92_RS07400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
INE92_RS07420	COG0438	transferase activity, transferring glycosyl groups
INE92_RS07465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
INE92_RS07495	COG0540	Belongs to the ATCase OTCase family
INE92_RS07500	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
INE92_RS07515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
INE92_RS07520	COG2759	Belongs to the formate--tetrahydrofolate ligase family
INE92_RS07525	COG2985	domain, Protein
INE92_RS07545	COG2207	Transcriptional regulator
INE92_RS07545	COG1917	Cupin 2, conserved barrel domain protein
INE92_RS07550	COG2207	Transcriptional regulator
INE92_RS07560	COG1690	Belongs to the RtcB family
INE92_RS07565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
INE92_RS07565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE92_RS07575	COG2431	L-lysine efflux transmembrane transporter activity
INE92_RS07580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INE92_RS07590	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
INE92_RS07595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
INE92_RS07600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE92_RS07605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
INE92_RS07610	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE92_RS07615	COG0356	it plays a direct role in the translocation of protons across the membrane
INE92_RS07625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
INE92_RS07630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
INE92_RS07640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
INE92_RS07645	COG0454	-acetyltransferase
INE92_RS07675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INE92_RS07685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
INE92_RS07690	COG1011	Hydrolase
INE92_RS07695	COG0534	Mate efflux family protein
INE92_RS07705	COG0577	efflux transmembrane transporter activity
INE92_RS07705	COG1136	(ABC) transporter
INE92_RS07720	COG2204	response regulator
INE92_RS07735	COG1151	hydroxylamine reductase activity
INE92_RS07740	COG2233	PERMEase
INE92_RS07750	COG1022	Amp-dependent synthetase and ligase
INE92_RS07755	COG0745	RESPONSE REGULATOR receiver
INE92_RS07760	COG5002	protein histidine kinase activity
INE92_RS07780	COG3118	belongs to the thioredoxin family
INE92_RS07860	COG5002	protein histidine kinase activity
INE92_RS07870	COG0352	thiamine-phosphate diphosphorylase activity
INE92_RS07875	COG2022	thiamine diphosphate biosynthetic process
INE92_RS07880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
INE92_RS07890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
INE92_RS07895	COG0352	thiamine-phosphate diphosphorylase activity
INE92_RS07935	COG0358	DNA primase activity
INE92_RS07945	COG1349	DNA-binding transcription factor activity
INE92_RS07950	COG4474	Belongs to the UPF0398 family
INE92_RS08025	COG4245	von Willebrand factor, type A
INE92_RS08040	COG4245	von Willebrand factor, type A
INE92_RS08075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INE92_RS08085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
INE92_RS08155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE92_RS08255	COG1192	Involved in chromosome partitioning
INE92_RS08280	COG0574	Belongs to the PEP-utilizing enzyme family
INE92_RS08280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INE92_RS08285	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INE92_RS08290	COG0564	pseudouridine synthase activity
INE92_RS08310	COG0024	Methionine aminopeptidase
INE92_RS08320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
INE92_RS08330	COG0481	GTPase activity
INE92_RS08355	COG0708	Exodeoxyribonuclease III
INE92_RS08370	COG0217	transcriptional regulatory protein
INE92_RS08375	COG0072	phenylalanine-tRNA ligase activity
INE92_RS08375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE92_RS08380	COG0305	Participates in initiation and elongation during chromosome replication
INE92_RS08385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
INE92_RS08390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INE92_RS08395	COG4657	Part of a membrane complex involved in electron transport
INE92_RS08400	COG4660	Part of a membrane complex involved in electron transport
INE92_RS08405	COG4659	FMN binding
INE92_RS08410	COG4658	electron transport chain
INE92_RS08415	COG4656	Part of a membrane complex involved in electron transport
INE92_RS08570	COG1086	Polysaccharide biosynthesis protein
INE92_RS08580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
INE92_RS08610	COG0504	CTP synthase activity
INE92_RS08615	COG0706	membrane insertase activity
INE92_RS08620	COG0534	Mate efflux family protein
INE92_RS08625	COG0823	Involved in the tonB-independent uptake of proteins
INE92_RS08625	COG1506	peptidase
INE92_RS08640	COG1983	PspC domain protein
INE92_RS08660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INE92_RS08670	COG1388	LysM domain
INE92_RS08670	COG3942	CHAP domain
INE92_RS08705	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
INE92_RS08710	COG0556	nucleotide-excision repair
INE92_RS08730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
INE92_RS08740	COG0842	Transport permease protein
INE92_RS08745	COG0842	Transport permease protein
INE92_RS08750	COG1131	(ABC) transporter
INE92_RS08765	COG1917	Cupin 2, conserved barrel domain protein
INE92_RS08765	COG2207	Transcriptional regulator
INE92_RS08775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
INE92_RS08780	COG0505	Belongs to the CarA family
INE92_RS08790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
INE92_RS08795	COG0067	glutamate synthase
INE92_RS08795	COG0069	glutamate synthase activity
INE92_RS08795	COG0070	glutamate synthase
INE92_RS08805	COG0367	asparagine synthase
INE92_RS08820	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
INE92_RS08825	COG0436	Aminotransferase
INE92_RS08835	COG0347	Belongs to the P(II) protein family
INE92_RS08840	COG0004	ammonium transporteR
INE92_RS08870	COG0490	domain, Protein
INE92_RS08870	COG0471	metal ion transport
INE92_RS08875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS08875	COG2205	protein histidine kinase activity
INE92_RS08880	COG1979	alcohol dehydrogenase
INE92_RS08890	COG0133	tryptophan synthase activity
INE92_RS08895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INE92_RS08905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INE92_RS08910	COG0134	indole-3-glycerol-phosphate synthase activity
INE92_RS08915	COG0135	phosphoribosylanthranilate isomerase activity
INE92_RS08920	COG0159	tryptophan synthase activity
INE92_RS08925	COG0252	asparaginase activity
INE92_RS08945	COG0745	RESPONSE REGULATOR receiver
INE92_RS08950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INE92_RS08985	COG0138	bifunctional purine biosynthesis protein purh
INE92_RS09000	COG1730	sister chromatid segregation
INE92_RS09005	COG3487	Iron-regulated protein
INE92_RS09030	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INE92_RS09030	COG1333	cytochrome c biogenesis protein
INE92_RS09035	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS09070	COG4771	TonB-dependent receptor
INE92_RS09080	COG4771	TonB-dependent receptor
INE92_RS09090	COG0490	domain, Protein
INE92_RS09090	COG2985	domain, Protein
INE92_RS09095	COG1230	cation diffusion facilitator family transporter
INE92_RS09110	COG1609	Transcriptional regulator
INE92_RS09115	COG2721	sulfolactate sulfo-lyase activity
INE92_RS09130	COG4452	Inner membrane protein CreD
INE92_RS09160	COG1733	regulation of RNA biosynthetic process
INE92_RS09180	COG0228	four-way junction DNA binding
INE92_RS09190	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
INE92_RS09200	COG1070	Carbohydrate kinase
INE92_RS09210	COG0738	Major facilitator superfamily
INE92_RS09225	COG2207	Transcriptional regulator
INE92_RS09260	COG1177	transmembrane transport
INE92_RS09265	COG1176	ABC-type spermidine putrescine transport system, permease component I
INE92_RS09270	COG3842	ATPase activity
INE92_RS09275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE92_RS09280	COG0058	SHG alpha-glucan phosphorylase activity
INE92_RS09290	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INE92_RS09310	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
INE92_RS09365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INE92_RS09370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE92_RS09375	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS09390	COG1295	ribonuclease BN
INE92_RS09395	COG0778	Nitroreductase
INE92_RS09405	COG0704	Plays a role in the regulation of phosphate uptake
INE92_RS09410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INE92_RS09415	COG0581	inorganic phosphate transmembrane transporter activity
INE92_RS09420	COG0573	inorganic phosphate transmembrane transporter activity
INE92_RS09430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INE92_RS09440	COG0586	Pfam SNARE associated Golgi protein
INE92_RS09450	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INE92_RS09465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INE92_RS09475	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
INE92_RS09520	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS09560	COG1216	Glycosyl transferase, family 2
INE92_RS09575	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
INE92_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS09620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INE92_RS09625	COG0497	DNA recombination
INE92_RS09640	COG0592	DNA-directed DNA polymerase activity
INE92_RS09660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INE92_RS09660	COG0321	lipoyl(octanoyl) transferase activity
INE92_RS09665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
INE92_RS09675	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE92_RS09680	COG0156	8-amino-7-oxononanoate synthase activity
INE92_RS09690	COG5002	protein histidine kinase activity
INE92_RS09700	COG0019	diaminopimelate decarboxylase activity
INE92_RS09705	COG0527	aspartate kinase activity
INE92_RS09710	COG2884	Cell division ATP-binding protein ftsE
INE92_RS09715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
INE92_RS09715	COG0140	phosphoribosyl-ATP diphosphatase activity
INE92_RS09720	COG0107	imidazoleglycerol-phosphate synthase activity
INE92_RS09725	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
INE92_RS09730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
INE92_RS09735	COG0788	formyltetrahydrofolate deformylase activity
INE92_RS09750	COG0693	protein deglycase activity
INE92_RS09770	COG0534	Mate efflux family protein
INE92_RS09780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INE92_RS09795	COG3831	ATPase activity
INE92_RS09795	COG4884	unkown
INE92_RS09800	COG2885	chlorophyll binding
INE92_RS09800	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE92_RS09880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INE92_RS09885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INE92_RS09900	COG4946	Tricorn protease homolog
INE92_RS09900	COG0823	Involved in the tonB-independent uptake of proteins
INE92_RS09900	COG1506	peptidase
INE92_RS09910	COG0655	NAD(P)H dehydrogenase (quinone) activity
INE92_RS09925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
INE92_RS09935	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
INE92_RS09950	COG4771	TonB-dependent receptor
INE92_RS10025	COG0681	Belongs to the peptidase S26 family
INE92_RS10045	COG3831	ATPase activity
INE92_RS10045	COG4884	unkown
INE92_RS10060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
INE92_RS10065	COG1162	GTPase activity
INE92_RS10095	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
INE92_RS10100	COG5002	protein histidine kinase activity
INE92_RS10110	COG1312	Catalyzes the dehydration of D-mannonate
INE92_RS10115	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS10120	COG1609	Transcriptional regulator
INE92_RS10135	COG2223	nitrite transmembrane transporter activity
INE92_RS10145	COG4771	TonB-dependent receptor
INE92_RS10155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
INE92_RS10155	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INE92_RS10170	COG2226	methyltransferase
INE92_RS10200	COG2205	protein histidine kinase activity
INE92_RS10200	COG0784	Response regulator, receiver
INE92_RS10205	COG0511	ligase activity, forming carbon-carbon bonds
INE92_RS10210	COG0439	Biotin carboxylase
INE92_RS10215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE92_RS10225	COG1620	l-lactate permease
INE92_RS10245	COG1690	Belongs to the RtcB family
INE92_RS10255	COG3279	Response regulator of the LytR AlgR family
INE92_RS10280	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS10295	COG0702	epimerase
INE92_RS10300	COG4771	TonB-dependent receptor
INE92_RS10315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INE92_RS10335	COG0628	permease
INE92_RS10340	COG1215	transferase activity, transferring glycosyl groups
INE92_RS10345	COG0456	acetyltransferase
INE92_RS10350	COG0189	ligase activity
INE92_RS10350	COG0569	domain protein
INE92_RS10355	COG1136	(ABC) transporter
INE92_RS10355	COG0577	efflux transmembrane transporter activity
INE92_RS10360	COG0436	Aminotransferase
INE92_RS10375	COG0488	(ABC) transporter
INE92_RS10390	COG0745	RESPONSE REGULATOR receiver
INE92_RS10445	COG4206	TonB-dependent receptor
INE92_RS10460	COG3033	Beta-eliminating lyase
INE92_RS10485	COG0629	single-stranded DNA binding
INE92_RS10490	COG1194	a g-specific adenine glycosylase
INE92_RS10500	COG1530	ribonuclease E activity
INE92_RS10550	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS10585	COG4771	TonB-dependent receptor
INE92_RS10590	COG1979	alcohol dehydrogenase
INE92_RS10605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INE92_RS10615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
INE92_RS10630	COG4191	Histidine kinase
INE92_RS10635	COG2204	response regulator
INE92_RS10655	COG0577	efflux transmembrane transporter activity
INE92_RS10665	COG1136	(ABC) transporter
INE92_RS10675	COG1252	NADH dehydrogenase
INE92_RS10680	COG1705	Flagellar rod assembly protein muramidase FlgJ
INE92_RS10685	COG0295	cytidine deaminase activity
INE92_RS10695	COG3059	membrane
INE92_RS10700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INE92_RS10705	COG0488	(ABC) transporter
INE92_RS10735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INE92_RS10755	COG1629	transport
INE92_RS10755	COG4206	TonB-dependent receptor
INE92_RS10770	COG0686	Belongs to the AlaDH PNT family
INE92_RS10820	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
INE92_RS10830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
INE92_RS10835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
INE92_RS10850	COG1595	DNA-templated transcription, initiation
INE92_RS10870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INE92_RS10875	COG1741	Belongs to the pirin family
INE92_RS10880	COG0259	pyridoxamine-phosphate oxidase activity
INE92_RS10895	COG0346	lactoylglutathione lyase activity
INE92_RS11035	COG3177	Filamentation induced by cAMP protein fic
INE92_RS11040	COG1396	sequence-specific DNA binding
INE92_RS11085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INE92_RS11085	COG1918	ferrous iron import across plasma membrane
INE92_RS11090	COG0037	tRNA processing
INE92_RS11105	COG3119	arylsulfatase activity
INE92_RS11110	COG0534	Mate efflux family protein
INE92_RS11115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INE92_RS11120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
INE92_RS11165	COG2003	Belongs to the UPF0758 family
INE92_RS11215	COG4372	Transposase
INE92_RS11240	COG4372	Transposase
INE92_RS11270	COG1983	PspC domain protein
INE92_RS11275	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INE92_RS11300	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE92_RS11315	COG0668	transmembrane transport
INE92_RS11325	COG3250	beta-galactosidase activity
INE92_RS11330	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS11335	COG3119	arylsulfatase activity
INE92_RS11345	COG4771	TonB-dependent receptor
INE92_RS11360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
INE92_RS11370	COG3292	Two component regulator propeller
INE92_RS11370	COG0745	RESPONSE REGULATOR receiver
INE92_RS11370	COG2205	protein histidine kinase activity
INE92_RS11370	COG0745	RESPONSE REGULATOR receiver
INE92_RS11370	COG2205	protein histidine kinase activity
INE92_RS11370	COG3292	Two component regulator propeller
INE92_RS11375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
INE92_RS11380	COG1830	Aldolase
INE92_RS11385	COG0588	phosphoglycerate mutase activity
INE92_RS11400	COG4206	TonB-dependent receptor
INE92_RS11400	COG1629	transport
INE92_RS11430	COG1119	ATPase activity
INE92_RS11435	COG3661	Belongs to the glycosyl hydrolase 67 family
INE92_RS11450	COG2211	Major facilitator Superfamily
INE92_RS11460	COG1523	belongs to the glycosyl hydrolase 13 family
INE92_RS11470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
INE92_RS11505	COG4372	Transposase
INE92_RS11525	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
INE92_RS11530	COG2814	Major facilitator Superfamily
INE92_RS11535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INE92_RS11540	COG0126	phosphoglycerate kinase activity
INE92_RS11555	COG2311	Membrane
INE92_RS11565	COG0424	maF-like protein
INE92_RS11585	COG0778	Nitroreductase
INE92_RS11595	COG0288	reversible hydration of carbon dioxide
INE92_RS11605	COG1629	transport
INE92_RS11620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE92_RS11630	COG0511	ligase activity, forming carbon-carbon bonds
INE92_RS11635	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
INE92_RS11640	COG0191	fructose-bisphosphate aldolase activity
INE92_RS11645	COG0254	rRNA binding
INE92_RS11650	COG1373	ATPase (AAA superfamily
INE92_RS11700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE92_RS11725	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
INE92_RS11730	COG0511	ligase activity, forming carbon-carbon bonds
INE92_RS11750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
INE92_RS11765	COG1280	lysine exporter protein (LysE YggA)
INE92_RS11775	COG0745	RESPONSE REGULATOR receiver
INE92_RS11775	COG2205	protein histidine kinase activity
INE92_RS11775	COG3292	Two component regulator propeller
INE92_RS11775	COG0745	RESPONSE REGULATOR receiver
INE92_RS11775	COG2205	protein histidine kinase activity
INE92_RS11775	COG3292	Two component regulator propeller
INE92_RS11790	COG1649	PFAM Uncharacterised BCR, COG1649
INE92_RS11810	COG1966	Carbon starvation protein
INE92_RS11815	COG1649	PFAM Uncharacterised BCR, COG1649
INE92_RS11835	COG4372	Transposase
INE92_RS11860	COG2113	Glycine betaine
INE92_RS11865	COG4176	ABC-type proline glycine betaine transport system permease component
INE92_RS11875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INE92_RS11885	COG3292	Two component regulator propeller
INE92_RS11885	COG2205	protein histidine kinase activity
INE92_RS11885	COG0745	RESPONSE REGULATOR receiver
INE92_RS11900	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
INE92_RS11900	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
INE92_RS11910	COG1621	beta-fructofuranosidase activity
INE92_RS11930	COG1629	transport
INE92_RS11940	COG1621	beta-fructofuranosidase activity
INE92_RS11950	COG1752	Esterase of the alpha-beta hydrolase superfamily
INE92_RS11955	COG0475	glutathione-regulated potassium exporter activity
INE92_RS11995	COG2205	protein histidine kinase activity
INE92_RS11995	COG2202	Pas domain
INE92_RS12000	COG2205	protein histidine kinase activity
INE92_RS12000	COG2202	Pas domain
INE92_RS12005	COG5002	protein histidine kinase activity
INE92_RS12035	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
INE92_RS12040	COG1960	acyl-CoA dehydrogenase activity
INE92_RS12050	COG0705	Rhomboid family
INE92_RS12065	COG1956	GAF domain-containing protein
INE92_RS12075	COG0484	heat shock protein binding
INE92_RS12080	COG2194	sulfuric ester hydrolase activity
INE92_RS12100	COG0028	Belongs to the TPP enzyme family
INE92_RS12130	COG0459	protein refolding
INE92_RS12135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
INE92_RS12165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
INE92_RS12175	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
INE92_RS12180	COG0124	histidyl-tRNA synthetase
INE92_RS12195	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
INE92_RS12220	COG0514	ATP-dependent DNA helicase (RecQ)
INE92_RS12230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INE92_RS12235	COG1368	sulfuric ester hydrolase activity
INE92_RS12240	COG0671	phosphoesterase, PA-phosphatase related
INE92_RS12245	COG0473	3-isopropylmalate dehydrogenase activity
INE92_RS12255	COG0066	3-isopropylmalate dehydratase activity
INE92_RS12260	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INE92_RS12265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
INE92_RS12330	COG1917	Cupin 2, conserved barrel domain protein
INE92_RS12330	COG4977	sequence-specific DNA binding
INE92_RS12370	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS12380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
INE92_RS12395	COG3118	belongs to the thioredoxin family
INE92_RS12400	COG0439	Biotin carboxylase
INE92_RS12410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INE92_RS12420	COG2873	o-acetylhomoserine
INE92_RS12425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
INE92_RS12460	COG4974	Belongs to the 'phage' integrase family
INE92_RS12535	COG1629	transport
INE92_RS12545	COG1192	Involved in chromosome partitioning
INE92_RS12570	COG1120	ATPase activity
INE92_RS12575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INE92_RS12640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
INE92_RS12650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
INE92_RS12655	COG1088	dTDP-glucose 4,6-dehydratase activity
INE92_RS12660	COG1575	Belongs to the MenA family. Type 1 subfamily
INE92_RS12725	COG0484	heat shock protein binding
INE92_RS12765	COG0358	DNA primase activity
INE92_RS12815	COG3344	reverse transcriptase
INE92_RS12835	COG3344	reverse transcriptase
INE92_RS12880	COG1192	Involved in chromosome partitioning
INE92_RS12925	COG1373	ATPase (AAA superfamily
INE92_RS12995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INE92_RS13070	COG0463	Glycosyl transferase, family 2
INE92_RS13095	COG0438	transferase activity, transferring glycosyl groups
INE92_RS13125	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
INE92_RS13130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE92_RS13135	COG0662	Cupin 2, conserved barrel domain protein
INE92_RS13135	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
INE92_RS13145	COG5002	protein histidine kinase activity
INE92_RS13145	COG0784	Response regulator, receiver
INE92_RS13150	COG2204	response regulator
INE92_RS13175	COG4974	Belongs to the 'phage' integrase family
INE92_RS13180	COG4974	Belongs to the 'phage' integrase family
INE92_RS13185	COG1408	metallophosphoesterase
INE92_RS13195	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
INE92_RS13200	COG0194	GDP metabolic process
INE92_RS13220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INE92_RS13225	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
INE92_RS13235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
INE92_RS13240	COG0750	zinc metalloprotease
INE92_RS13250	COG2814	Major facilitator Superfamily
INE92_RS13260	COG1328	CTP reductase activity
INE92_RS13315	COG1629	transport
INE92_RS13315	COG4206	TonB-dependent receptor
INE92_RS13320	COG1629	transport
INE92_RS13320	COG4206	TonB-dependent receptor
INE92_RS13345	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS13375	COG1538	Outer membrane efflux protein
INE92_RS13420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS13435	COG0561	phosphatase activity
INE92_RS13440	COG4771	TonB-dependent receptor
INE92_RS13470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INE92_RS13515	COG1505	serine-type exopeptidase activity
INE92_RS13530	COG3119	arylsulfatase activity
INE92_RS13545	COG0617	tRNA 3'-terminal CCA addition
INE92_RS13560	COG0632	four-way junction helicase activity
INE92_RS13565	COG0673	inositol 2-dehydrogenase activity
INE92_RS13570	COG1272	protein, Hemolysin III
INE92_RS13575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
INE92_RS13580	COG4206	TonB-dependent receptor
INE92_RS13580	COG1629	transport
INE92_RS13595	COG2204	response regulator
INE92_RS13600	COG0488	(ABC) transporter
INE92_RS13650	COG1595	DNA-templated transcription, initiation
INE92_RS13665	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
INE92_RS13675	COG1522	sequence-specific DNA binding
INE92_RS13705	COG0811	peptide transport
INE92_RS13715	COG0084	hydrolase, TatD family'
INE92_RS13735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
INE92_RS13740	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
INE92_RS13745	COG0205	6-phosphofructokinase activity
INE92_RS13805	COG0372	Belongs to the citrate synthase family
INE92_RS13815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INE92_RS13820	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE92_RS13830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
INE92_RS13845	COG0028	Belongs to the TPP enzyme family
INE92_RS13850	COG0129	dihydroxy-acid dehydratase activity
INE92_RS13865	COG3681	Belongs to the UPF0597 family
INE92_RS13885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
INE92_RS13950	COG4206	TonB-dependent receptor
INE92_RS13950	COG1629	transport
INE92_RS13960	COG1595	DNA-templated transcription, initiation
INE92_RS13965	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE92_RS13965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE92_RS13970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
INE92_RS13975	COG2985	domain, Protein
INE92_RS13975	COG0569	domain protein
INE92_RS14015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INE92_RS14030	COG3537	Alpha-1,2-mannosidase
INE92_RS14050	COG0702	epimerase
INE92_RS14055	COG4206	TonB-dependent receptor
INE92_RS14055	COG1629	transport
INE92_RS14060	COG1940	carbohydrate kinase activity
INE92_RS14070	COG2188	Transcriptional regulator
INE92_RS14140	COG1609	Transcriptional regulator
INE92_RS14140	COG2207	Transcriptional regulator
INE92_RS14145	COG0534	Mate efflux family protein
INE92_RS14150	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INE92_RS14155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
INE92_RS14160	COG0166	Belongs to the GPI family
INE92_RS14175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INE92_RS14195	COG2502	aspartate--ammonia ligase
INE92_RS14200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
INE92_RS14215	COG3876	Protein conserved in bacteria
INE92_RS14270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INE92_RS14310	COG2315	Protein conserved in bacteria
INE92_RS14345	COG0860	N-Acetylmuramoyl-L-alanine amidase
INE92_RS14355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
INE92_RS14360	COG0778	Nitroreductase
INE92_RS14370	COG1640	4-alpha-glucanotransferase
INE92_RS14390	COG1216	Glycosyl transferase, family 2
INE92_RS14400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE92_RS14405	COG1022	Amp-dependent synthetase and ligase
INE92_RS14440	COG0359	binds to the 23S rRNA
INE92_RS14445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
INE92_RS14450	COG0360	Binds together with S18 to 16S ribosomal RNA
INE92_RS14475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INE92_RS14480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INE92_RS14515	COG2431	L-lysine efflux transmembrane transporter activity
INE92_RS14545	COG1373	ATPase (AAA superfamily
INE92_RS14550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
INE92_RS14565	COG4206	TonB-dependent receptor
INE92_RS14565	COG1629	transport
INE92_RS14580	COG2234	aminopeptidase activity
INE92_RS14590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INE92_RS14595	COG0802	atpase or kinase
INE92_RS14610	COG0714	Associated with various cellular activities
INE92_RS14645	COG3118	belongs to the thioredoxin family
INE92_RS14655	COG0688	phosphatidylethanolamine metabolic process
INE92_RS14660	COG1183	phosphatidylcholine synthase activity
INE92_RS14680	COG0792	nuclease activity
INE92_RS14705	COG0534	Mate efflux family protein
INE92_RS14710	COG0528	UMP kinase activity
INE92_RS14725	COG3250	beta-galactosidase activity
INE92_RS14735	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE92_RS14740	COG4206	TonB-dependent receptor
INE92_RS14740	COG1629	transport
INE92_RS14745	COG2205	protein histidine kinase activity
INE92_RS14745	COG3292	Two component regulator propeller
INE92_RS14745	COG0745	RESPONSE REGULATOR receiver
INE92_RS14755	COG0233	cytoplasmic translational termination
INE92_RS14760	COG1162	GTPase activity
INE92_RS14775	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
INE92_RS14790	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
INE92_RS14790	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
INE92_RS14805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INE92_RS14815	COG1629	transport
INE92_RS14815	COG4206	TonB-dependent receptor
INE92_RS14820	COG4974	Belongs to the 'phage' integrase family
INE92_RS14825	COG4771	TonB-dependent receptor
INE92_RS14835	COG2095	MarC family integral membrane protein
INE92_RS14850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INE92_RS14860	COG1435	thymidine kinase activity
INE92_RS14865	COG0628	permease
INE92_RS14900	COG1830	Aldolase
INE92_RS14905	COG0588	phosphoglycerate mutase activity
INE92_RS14915	COG1595	DNA-templated transcription, initiation
INE92_RS14920	COG0205	6-phosphofructokinase activity
INE92_RS14925	COG0058	SHG alpha-glucan phosphorylase activity
INE92_RS14930	COG0010	Belongs to the arginase family
INE92_RS14935	COG4413	Urea transporter
INE92_RS14940	COG1396	sequence-specific DNA binding
INE92_RS14950	COG4771	TonB-dependent receptor
INE92_RS14980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INE92_RS15010	COG2076	Multidrug Resistance protein
INE92_RS15025	COG0589	response to stress
INE92_RS15025	COG0475	glutathione-regulated potassium exporter activity
INE92_RS15050	COG2207	Transcriptional regulator
INE92_RS15060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INE92_RS15065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INE92_RS15080	COG0534	Mate efflux family protein
INE92_RS15100	COG1522	sequence-specific DNA binding
INE92_RS15115	COG0668	transmembrane transport
INE92_RS15145	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
INE92_RS15150	COG0527	aspartate kinase activity
INE92_RS15150	COG0460	homoserine dehydrogenase
INE92_RS15155	COG0252	asparaginase activity
INE92_RS15165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INE92_RS15170	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
INE92_RS15180	COG4771	TonB-dependent receptor
INE92_RS15195	COG0826	peptidase U32
INE92_RS15200	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
INE92_RS15215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
INE92_RS15245	COG0519	Catalyzes the synthesis of GMP from XMP
INE92_RS15260	COG4771	TonB-dependent receptor
INE92_RS15300	COG1131	(ABC) transporter
INE92_RS15315	COG5002	protein histidine kinase activity
INE92_RS15320	COG2205	protein histidine kinase activity
INE92_RS15330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
INE92_RS15335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
INE92_RS15340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
INE92_RS15400	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS15410	COG0471	metal ion transport
INE92_RS15445	COG0702	epimerase
INE92_RS15450	COG4771	TonB-dependent receptor
INE92_RS15475	COG0616	signal peptide processing
INE92_RS15480	COG1663	tetraacyldisaccharide 4'-kinase activity
INE92_RS15485	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
INE92_RS15490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
INE92_RS15510	COG0513	Belongs to the DEAD box helicase family
INE92_RS15515	COG2070	2-Nitropropane dioxygenase
INE92_RS15520	COG0724	RNA recognition motif
INE92_RS15535	COG3973	AAA domain
INE92_RS15545	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS15685	COG2204	response regulator
INE92_RS15690	COG0446	pyridine nucleotide-disulphide oxidoreductase
INE92_RS15710	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS15715	COG0737	Belongs to the 5'-nucleotidase family
INE92_RS15720	COG0737	Belongs to the 5'-nucleotidase family
INE92_RS15725	COG0335	large ribosomal subunit rRNA binding
INE92_RS15735	COG0577	efflux transmembrane transporter activity
INE92_RS15735	COG1136	(ABC) transporter
INE92_RS15740	COG0577	efflux transmembrane transporter activity
INE92_RS15740	COG1136	(ABC) transporter
INE92_RS15745	COG0577	efflux transmembrane transporter activity
INE92_RS15745	COG1136	(ABC) transporter
INE92_RS15760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INE92_RS15760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INE92_RS15770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INE92_RS15785	COG2996	Protein conserved in bacteria
INE92_RS15790	COG0039	L-malate dehydrogenase activity
INE92_RS15800	COG2217	Heavy metal translocating P-type atpase
INE92_RS15810	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
INE92_RS15815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
INE92_RS15820	COG0509	glycine decarboxylation via glycine cleavage system
INE92_RS15835	COG0006	proline dipeptidase activity
INE92_RS15840	COG3458	cephalosporin-C deacetylase activity
INE92_RS15855	COG1283	sodium-dependent phosphate transmembrane transporter activity
INE92_RS15860	COG1773	rubredoxin
INE92_RS15870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INE92_RS15875	COG1011	Hydrolase
INE92_RS15880	COG0196	riboflavin kinase activity
INE92_RS15885	COG1266	CAAX protease self-immunity
INE92_RS15890	COG2166	iron-sulfur cluster assembly
INE92_RS15895	COG2234	aminopeptidase activity
INE92_RS15900	COG1619	proteins homologs of microcin C7 resistance protein MccF
INE92_RS15905	COG0280	phosphate acetyltransferase
INE92_RS15910	COG3426	butyrate kinase activity
INE92_RS15935	COG1185	polyribonucleotide nucleotidyltransferase activity
INE92_RS15945	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INE92_RS15965	COG0076	glutamate decarboxylase activity
INE92_RS15970	COG2066	Belongs to the glutaminase family
INE92_RS15980	COG0531	amino acid
INE92_RS16020	COG3345	alpha-galactosidase
INE92_RS16040	COG1131	(ABC) transporter
INE92_RS16110	COG0667	Aldo Keto reductase
INE92_RS16115	COG1696	Membrane protein involved in D-alanine export
INE92_RS16150	COG1309	transcriptional regulator
INE92_RS16155	COG2986	histidine ammonia-lyase
INE92_RS16165	COG1228	amidohydrolase
INE92_RS16175	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
INE92_RS16185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE92_RS16200	COG0203	ribosomal protein L17
INE92_RS16205	COG0202	RNA polymerase activity
INE92_RS16210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
INE92_RS16215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
INE92_RS16220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
INE92_RS16225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
INE92_RS16230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
INE92_RS16245	COG0200	Binds to the 23S rRNA
INE92_RS16250	COG1841	ribosomal large subunit assembly
INE92_RS16255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
INE92_RS16260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
INE92_RS16265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
INE92_RS16270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
INE92_RS16275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
INE92_RS16280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
INE92_RS16285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
INE92_RS16290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
INE92_RS16295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
INE92_RS16300	COG0255	Belongs to the universal ribosomal protein uL29 family
INE92_RS16305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
INE92_RS16310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
INE92_RS16315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
INE92_RS16320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
INE92_RS16325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
INE92_RS16330	COG0089	rRNA binding
INE92_RS16335	COG0088	Forms part of the polypeptide exit tunnel
INE92_RS16340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
INE92_RS16345	COG0051	transcription antitermination factor activity, RNA binding
INE92_RS16350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INE92_RS16355	COG0049	tRNA binding
INE92_RS16360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
INE92_RS16370	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
INE92_RS16375	COG0085	RNA polymerase activity
INE92_RS16380	COG0222	ribosome binding
INE92_RS16385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
INE92_RS16390	COG0081	regulation of translation
INE92_RS16395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
INE92_RS16405	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INE92_RS16415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
INE92_RS16445	COG4974	Belongs to the 'phage' integrase family
INE92_RS16450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
INE92_RS16455	COG0006	proline dipeptidase activity
INE92_RS16460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
INE92_RS16470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INE92_RS16480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
INE92_RS16490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INE92_RS16515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INE92_RS16520	COG1027	Aspartate ammonia-lyase
INE92_RS16525	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
INE92_RS16530	COG0252	asparaginase activity
INE92_RS16545	COG4804	nuclease activity
INE92_RS16550	COG3292	Two component regulator propeller
INE92_RS16550	COG2205	protein histidine kinase activity
INE92_RS16550	COG0745	RESPONSE REGULATOR receiver
INE92_RS16555	COG0584	glycerophosphoryl diester phosphodiesterase
INE92_RS16600	COG3940	Belongs to the glycosyl hydrolase 43 family
INE92_RS16640	COG2096	Adenosyltransferase
INE92_RS16700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE92_RS16705	COG0793	Belongs to the peptidase S41A family
INE92_RS16715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
INE92_RS16745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
INE92_RS16750	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
INE92_RS16765	COG2059	Chromate
INE92_RS16780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
INE92_RS16785	COG1396	sequence-specific DNA binding
INE92_RS16790	COG0318	PFAM AMP-dependent synthetase and ligase
INE92_RS16795	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
INE92_RS16795	COG0662	Cupin 2, conserved barrel domain protein
INE92_RS16825	COG0346	lactoylglutathione lyase activity
INE92_RS16870	COG1040	competence protein
INE92_RS16915	COG2610	gluconate transmembrane transporter activity
INE92_RS16920	COG1929	Belongs to the glycerate kinase type-1 family
INE92_RS16940	COG1629	transport
INE92_RS16950	COG1609	Transcriptional regulator
INE92_RS16955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE92_RS16960	COG4206	TonB-dependent receptor
INE92_RS16960	COG1629	transport
INE92_RS16990	COG2382	esterase
INE92_RS16990	COG3693	PFAM glycoside hydrolase, family 10
INE92_RS17010	COG3634	alkyl hydroperoxide reductase activity
INE92_RS17020	COG2816	NAD+ diphosphatase activity
INE92_RS17040	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS17105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INE92_RS17165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INE92_RS17180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
INE92_RS17210	COG0561	phosphatase activity
INE92_RS17215	COG4771	TonB-dependent receptor
INE92_RS17250	COG3292	Two component regulator propeller
INE92_RS17250	COG2205	protein histidine kinase activity
INE92_RS17250	COG0745	RESPONSE REGULATOR receiver
INE92_RS17270	COG0018	arginyl-trna synthetase
INE92_RS17280	COG0705	Rhomboid family
INE92_RS17295	COG0339	signal peptide processing
INE92_RS17300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
INE92_RS17310	COG0674	pyruvate-flavodoxin oxidoreductase activity
INE92_RS17310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INE92_RS17315	COG1013	pyruvate-flavodoxin oxidoreductase activity
INE92_RS17320	COG4974	Belongs to the 'phage' integrase family
INE92_RS17360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
INE92_RS17385	COG0739	heme binding
INE92_RS17385	COG0741	lytic transglycosylase activity
INE92_RS17385	COG1196	nuclear chromosome segregation
INE92_RS17415	COG1629	transport
INE92_RS17450	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
INE92_RS17460	COG3458	cephalosporin-C deacetylase activity
INE92_RS17490	COG0622	Phosphoesterase
INE92_RS17635	COG1373	ATPase (AAA superfamily
INE92_RS17645	COG3250	beta-galactosidase activity
INE92_RS17650	COG3458	cephalosporin-C deacetylase activity
INE92_RS17655	COG3345	alpha-galactosidase
INE92_RS17660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INE92_RS17700	COG4771	TonB-dependent receptor
INE92_RS17725	COG4591	ABC-type transport system involved in lipoprotein release permease component
INE92_RS17730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
INE92_RS17750	COG4974	Belongs to the 'phage' integrase family
INE92_RS17765	COG0606	chelatase, subunit chli
INE92_RS17770	COG2205	protein histidine kinase activity
INE92_RS17780	COG0702	epimerase
INE92_RS17785	COG4771	TonB-dependent receptor
INE92_RS17795	COG1501	Belongs to the glycosyl hydrolase 31 family
INE92_RS17800	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS17820	COG4771	TonB-dependent receptor
INE92_RS17840	COG0745	RESPONSE REGULATOR receiver
INE92_RS17840	COG2205	protein histidine kinase activity
INE92_RS17840	COG3292	Two component regulator propeller
INE92_RS17855	COG0673	inositol 2-dehydrogenase activity
INE92_RS17860	COG0673	inositol 2-dehydrogenase activity
INE92_RS17875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE92_RS17875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INE92_RS17890	COG3475	LICD family
INE92_RS17905	COG0438	transferase activity, transferring glycosyl groups
INE92_RS17935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
INE92_RS17940	COG0545	Peptidyl-prolyl cis-trans isomerase
INE92_RS17945	COG0545	Peptidyl-prolyl cis-trans isomerase
INE92_RS17965	COG0561	phosphatase activity
INE92_RS18040	COG4771	TonB-dependent receptor
INE92_RS18045	COG0702	epimerase
INE92_RS18055	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
INE92_RS18065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
INE92_RS18075	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE92_RS18080	COG2211	Major facilitator Superfamily
INE92_RS18085	COG3408	Glycogen debranching enzyme
INE92_RS18110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
INE92_RS18115	COG0793	Belongs to the peptidase S41A family
INE92_RS18115	COG3409	Peptidoglycan-binding domain 1 protein
INE92_RS18140	COG0702	epimerase
INE92_RS18145	COG1629	transport
INE92_RS18145	COG4206	TonB-dependent receptor
INE92_RS18150	COG3292	Two component regulator propeller
INE92_RS18150	COG2205	protein histidine kinase activity
INE92_RS18150	COG0745	RESPONSE REGULATOR receiver
INE92_RS18170	COG1053	succinate dehydrogenase
INE92_RS18175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
INE92_RS18205	COG2207	Transcriptional regulator
INE92_RS18205	COG1609	Transcriptional regulator
INE92_RS18375	COG3392	D12 class N6 adenine-specific DNA methyltransferase
INE92_RS18510	COG0758	DNA mediated transformation
INE92_RS18520	COG0826	peptidase U32
INE92_RS18525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INE92_RS18550	COG1629	transport
INE92_RS18550	COG4206	TonB-dependent receptor
INE92_RS18585	COG0557	exoribonuclease II activity
INE92_RS18595	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS18615	COG0702	epimerase
INE92_RS18620	COG1629	transport
INE92_RS18620	COG4206	TonB-dependent receptor
INE92_RS18630	COG5002	protein histidine kinase activity
INE92_RS18640	COG4206	TonB-dependent receptor
INE92_RS18640	COG1629	transport
INE92_RS18655	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS18660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
INE92_RS18665	COG1917	Cupin 2, conserved barrel domain protein
INE92_RS18675	COG4124	Belongs to the glycosyl hydrolase 26 family
INE92_RS18695	COG0702	epimerase
INE92_RS18700	COG4771	TonB-dependent receptor
INE92_RS18705	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE92_RS18740	COG0702	epimerase
INE92_RS18745	COG4771	TonB-dependent receptor
INE92_RS18790	COG0745	RESPONSE REGULATOR receiver
INE92_RS18790	COG2205	protein histidine kinase activity
INE92_RS18790	COG3292	Two component regulator propeller
INE92_RS18805	COG4206	TonB-dependent receptor
INE92_RS18805	COG1629	transport
INE92_RS18815	COG4206	TonB-dependent receptor
INE92_RS18815	COG1629	transport
INE92_RS18840	COG3119	arylsulfatase activity
INE92_RS18850	COG2814	Major facilitator Superfamily
INE92_RS18855	COG0012	GTP binding
INE92_RS18860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
INE92_RS18865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
INE92_RS18870	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INE92_RS18880	COG1629	transport
INE92_RS18930	COG4771	TonB-dependent receptor
INE92_RS18935	COG3537	Alpha-1,2-mannosidase
INE92_RS18945	COG1785	Belongs to the alkaline phosphatase family
INE92_RS18955	COG0697	spore germination
INE92_RS18970	COG3250	beta-galactosidase activity
INE92_RS18975	COG0495	leucyl-tRNA aminoacylation
INE92_RS18980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INE92_RS18985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
INE92_RS18990	COG1360	Flagellar Motor Protein
INE92_RS18995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
INE92_RS19025	COG1629	transport
INE92_RS19025	COG4206	TonB-dependent receptor
INE92_RS19055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INE92_RS19055	COG0731	radical SAM domain protein
INE92_RS19070	COG2205	protein histidine kinase activity
INE92_RS19070	COG2198	Histidine kinase
INE92_RS19070	COG0784	Response regulator, receiver
INE92_RS19070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS19080	COG1629	transport
INE92_RS19100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS19150	COG2205	protein histidine kinase activity
INE92_RS19150	COG3292	Two component regulator propeller
INE92_RS19150	COG3292	Two component regulator propeller
INE92_RS19150	COG2205	protein histidine kinase activity
INE92_RS19150	COG0745	RESPONSE REGULATOR receiver
INE92_RS19150	COG0745	RESPONSE REGULATOR receiver
INE92_RS19185	COG4206	TonB-dependent receptor
INE92_RS19185	COG1629	transport
INE92_RS19200	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS19205	COG0659	secondary active sulfate transmembrane transporter activity
INE92_RS19210	COG1592	Rubrerythrin
INE92_RS19230	COG0582	viral genome integration into host DNA
INE92_RS19275	COG4974	Belongs to the 'phage' integrase family
INE92_RS19310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INE92_RS19310	COG0551	DNA topoisomerase type I activity
INE92_RS19330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS19330	COG0784	Response regulator, receiver
INE92_RS19330	COG2205	protein histidine kinase activity
INE92_RS19330	COG2198	Histidine kinase
INE92_RS19450	COG4974	Belongs to the 'phage' integrase family
INE92_RS19455	COG0582	viral genome integration into host DNA
INE92_RS19460	COG4974	Belongs to the 'phage' integrase family
INE92_RS19465	COG0358	DNA primase activity
INE92_RS19480	COG4974	Belongs to the 'phage' integrase family
INE92_RS19485	COG4974	Belongs to the 'phage' integrase family
INE92_RS19490	COG4974	Belongs to the 'phage' integrase family
INE92_RS19565	COG3292	Two component regulator propeller
INE92_RS19565	COG2205	protein histidine kinase activity
INE92_RS19565	COG0745	RESPONSE REGULATOR receiver
INE92_RS19575	COG4771	TonB-dependent receptor
INE92_RS19590	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
INE92_RS19620	COG2027	D-alanyl-D-alanine carboxypeptidase
INE92_RS19625	COG0427	acetyl-CoA hydrolase
INE92_RS19635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INE92_RS19705	COG2177	Part of the ABC transporter FtsEX involved in
INE92_RS19715	COG1968	undecaprenyl-diphosphatase activity
INE92_RS19720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
INE92_RS19725	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INE92_RS19730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
INE92_RS19740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
INE92_RS19770	COG0594	ribonuclease P activity
INE92_RS19775	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
INE92_RS19785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
INE92_RS19805	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
INE92_RS19810	COG1028	Short-chain dehydrogenase reductase Sdr
INE92_RS19850	COG0726	polysaccharide deacetylase
INE92_RS19860	COG1121	(ABC) transporter
INE92_RS19870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INE92_RS19870	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
INE92_RS19875	COG1238	metal cluster binding
INE92_RS19890	COG1506	peptidase
INE92_RS19890	COG0823	Involved in the tonB-independent uptake of proteins
INE92_RS19900	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INE92_RS19900	COG0116	Belongs to the methyltransferase superfamily
INE92_RS19905	COG1045	serine acetyltransferase
INE92_RS19915	COG3279	Response regulator of the LytR AlgR family
INE92_RS19925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INE92_RS19925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INE92_RS19930	COG0142	geranyltranstransferase activity
INE92_RS19940	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
INE92_RS19945	COG1694	Mazg nucleotide pyrophosphohydrolase
INE92_RS19950	COG1490	D-aminoacyl-tRNA deacylase activity
INE92_RS19955	COG0322	excinuclease ABC activity
INE92_RS19960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INE92_RS19965	COG0445	tRNA wobble uridine modification
INE92_RS19980	COG4771	TonB-dependent receptor
INE92_RS20030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
INE92_RS20035	COG2715	membrane protein required for spore maturation
INE92_RS20040	COG2255	four-way junction helicase activity
INE92_RS20060	COG3591	Belongs to the peptidase S1B family
INE92_RS20065	COG0513	Belongs to the DEAD box helicase family
INE92_RS20090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INE92_RS20105	COG0612	Peptidase, M16
INE92_RS20115	COG0584	glycerophosphoryl diester phosphodiesterase
INE92_RS20135	COG0702	epimerase
INE92_RS20140	COG4771	TonB-dependent receptor
INE92_RS20150	COG1595	DNA-templated transcription, initiation
INE92_RS20165	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
INE92_RS20190	COG0702	epimerase
INE92_RS20205	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS20250	COG0681	Belongs to the peptidase S26 family
INE92_RS20260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
INE92_RS20290	COG1215	transferase activity, transferring glycosyl groups
INE92_RS20310	COG5492	domain, Protein
INE92_RS20330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INE92_RS20340	COG0702	epimerase
INE92_RS20345	COG4771	TonB-dependent receptor
INE92_RS20350	COG3119	arylsulfatase activity
INE92_RS20355	COG0745	RESPONSE REGULATOR receiver
INE92_RS20355	COG2205	protein histidine kinase activity
INE92_RS20355	COG3292	Two component regulator propeller
INE92_RS20355	COG3292	Two component regulator propeller
INE92_RS20355	COG2205	protein histidine kinase activity
INE92_RS20355	COG0745	RESPONSE REGULATOR receiver
INE92_RS20420	COG0582	viral genome integration into host DNA
INE92_RS20435	COG0768	penicillin binding
INE92_RS20440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INE92_RS20495	COG0702	epimerase
INE92_RS20500	COG1629	transport
INE92_RS20510	COG1629	transport
INE92_RS20530	COG0738	Major facilitator superfamily
INE92_RS20545	COG1940	carbohydrate kinase activity
INE92_RS20550	COG3250	beta-galactosidase activity
INE92_RS20560	COG1609	Transcriptional regulator
INE92_RS20570	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE92_RS20575	COG1538	Outer membrane efflux protein
INE92_RS20585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INE92_RS20590	COG3250	beta-galactosidase activity
INE92_RS20655	COG1629	transport
INE92_RS20655	COG4206	TonB-dependent receptor
INE92_RS20660	COG0702	epimerase
INE92_RS20665	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS20670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
INE92_RS20680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS20685	COG3119	arylsulfatase activity
INE92_RS20690	COG5492	domain, Protein
INE92_RS20695	COG0215	cysteine-tRNA ligase activity
INE92_RS20700	COG0561	phosphatase activity
INE92_RS20715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
INE92_RS20720	COG0482	sulfurtransferase activity
INE92_RS20730	COG0205	6-phosphofructokinase activity
INE92_RS20735	COG0571	ribonuclease III activity
INE92_RS20740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INE92_RS20745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INE92_RS20750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
INE92_RS20755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INE92_RS20790	COG0438	transferase activity, transferring glycosyl groups
INE92_RS20795	COG3475	LICD family
INE92_RS20800	COG4750	Nucleotidyl transferase
INE92_RS20815	COG1216	Glycosyl transferase, family 2
INE92_RS20840	COG1216	Glycosyl transferase, family 2
INE92_RS20875	COG1132	(ABC) transporter
INE92_RS20885	COG0463	Glycosyl transferase, family 2
INE92_RS20895	COG1368	sulfuric ester hydrolase activity
INE92_RS20905	COG0328	RNA-DNA hybrid ribonuclease activity
INE92_RS20905	COG3341	Caulimovirus viroplasmin
INE92_RS20915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
INE92_RS20925	COG0326	Molecular chaperone. Has ATPase activity
INE92_RS20935	COG1166	arginine decarboxylase activity
INE92_RS20940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
INE92_RS20945	COG1595	DNA-templated transcription, initiation
INE92_RS21040	COG4974	Belongs to the 'phage' integrase family
INE92_RS21045	COG4974	Belongs to the 'phage' integrase family
INE92_RS21050	COG4974	Belongs to the 'phage' integrase family
INE92_RS21070	COG0358	DNA primase activity
INE92_RS21075	COG4974	Belongs to the 'phage' integrase family
INE92_RS21080	COG0582	viral genome integration into host DNA
INE92_RS21085	COG4974	Belongs to the 'phage' integrase family
INE92_RS21200	COG2204	response regulator
INE92_RS21205	COG2205	protein histidine kinase activity
INE92_RS21205	COG2198	Histidine kinase
INE92_RS21205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS21205	COG0784	Response regulator, receiver
INE92_RS21260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INE92_RS21260	COG0551	DNA topoisomerase type I activity
INE92_RS21295	COG4974	Belongs to the 'phage' integrase family
INE92_RS21320	COG0779	Required for maturation of 30S ribosomal subunits
INE92_RS21325	COG0195	Participates in both transcription termination and antitermination
INE92_RS21330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
INE92_RS21340	COG0719	Fe-S assembly protein
INE92_RS21345	COG0396	ATPase activity
INE92_RS21350	COG0719	Fe-S assembly protein
INE92_RS21355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INE92_RS21360	COG0393	Putative heavy-metal-binding
INE92_RS21370	COG3292	Two component regulator propeller
INE92_RS21370	COG0745	RESPONSE REGULATOR receiver
INE92_RS21370	COG2205	protein histidine kinase activity
INE92_RS21375	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
INE92_RS21380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
INE92_RS21395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
INE92_RS21410	COG0187	DNA topoisomerase II activity
INE92_RS21415	COG0268	Binds directly to 16S ribosomal RNA
INE92_RS21425	COG1381	Involved in DNA repair and RecF pathway recombination
INE92_RS21500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
INE92_RS21515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
INE92_RS21520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
INE92_RS21525	COG0772	Belongs to the SEDS family
INE92_RS21530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
INE92_RS21535	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INE92_RS21540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INE92_RS21555	COG0275	rRNA processing
INE92_RS21560	COG2001	Belongs to the MraZ family
INE92_RS21565	COG1595	DNA-templated transcription, initiation
INE92_RS21580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
INE92_RS21585	COG2205	protein histidine kinase activity
INE92_RS21585	COG0745	RESPONSE REGULATOR receiver
INE92_RS21585	COG3292	Two component regulator propeller
INE92_RS21585	COG0745	RESPONSE REGULATOR receiver
INE92_RS21585	COG2205	protein histidine kinase activity
INE92_RS21585	COG3292	Two component regulator propeller
INE92_RS21590	COG3940	Belongs to the glycosyl hydrolase 43 family
INE92_RS21600	COG4771	TonB-dependent receptor
INE92_RS21605	COG0702	epimerase
INE92_RS21630	COG0756	dUTP diphosphatase activity
INE92_RS21645	COG4942	peptidase
INE92_RS21680	COG3119	arylsulfatase activity
INE92_RS21695	COG3408	Glycogen debranching enzyme
INE92_RS21695	COG3119	arylsulfatase activity
INE92_RS21730	COG4206	TonB-dependent receptor
INE92_RS21730	COG1629	transport
INE92_RS21760	COG3537	Alpha-1,2-mannosidase
INE92_RS21815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE92_RS21835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INE92_RS21840	COG1595	DNA-templated transcription, initiation
INE92_RS21850	COG4771	TonB-dependent receptor
INE92_RS21875	COG1022	Amp-dependent synthetase and ligase
INE92_RS21905	COG2954	triphosphatase activity
INE92_RS21940	COG1864	DNA RNA non-specific endonuclease
INE92_RS21940	COG3591	Belongs to the peptidase S1B family
INE92_RS21975	COG0561	phosphatase activity
INE92_RS21980	COG4771	TonB-dependent receptor
INE92_RS22025	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS22075	COG4974	Belongs to the 'phage' integrase family
INE92_RS22080	COG4974	Belongs to the 'phage' integrase family
INE92_RS22085	COG4974	Belongs to the 'phage' integrase family
INE92_RS22150	COG1538	Outer membrane efflux protein
INE92_RS22155	COG0784	Response regulator, receiver
INE92_RS22155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS22155	COG2198	Histidine kinase
INE92_RS22155	COG2205	protein histidine kinase activity
INE92_RS22220	COG2271	Major facilitator Superfamily
INE92_RS22230	COG1629	transport
INE92_RS22265	COG1595	DNA-templated transcription, initiation
INE92_RS22270	COG0673	inositol 2-dehydrogenase activity
INE92_RS22275	COG0673	inositol 2-dehydrogenase activity
INE92_RS22300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INE92_RS22310	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS22330	COG1629	transport
INE92_RS22340	COG2207	Transcriptional regulator
INE92_RS22340	COG1609	Transcriptional regulator
INE92_RS22350	COG1373	ATPase (AAA superfamily
INE92_RS22355	COG0423	glycine-tRNA ligase activity
INE92_RS22380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
INE92_RS22380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
INE92_RS22395	COG1609	Transcriptional regulator
INE92_RS22410	COG0738	Major facilitator superfamily
INE92_RS22415	COG1063	alcohol dehydrogenase
INE92_RS22425	COG1472	Belongs to the glycosyl hydrolase 3 family
INE92_RS22430	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS22435	COG1501	Belongs to the glycosyl hydrolase 31 family
INE92_RS22445	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS22450	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS22455	COG4771	TonB-dependent receptor
INE92_RS22465	COG1629	transport
INE92_RS22495	COG2382	esterase
INE92_RS22500	COG3507	Belongs to the glycosyl hydrolase 43 family
INE92_RS22505	COG3292	Two component regulator propeller
INE92_RS22505	COG2205	protein histidine kinase activity
INE92_RS22505	COG0745	RESPONSE REGULATOR receiver
INE92_RS22520	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
INE92_RS22530	COG2211	Major facilitator Superfamily
INE92_RS22540	COG0463	Glycosyl transferase, family 2
INE92_RS22540	COG1216	Glycosyl transferase, family 2
INE92_RS22545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INE92_RS22600	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INE92_RS22605	COG0589	response to stress
INE92_RS22605	COG0475	glutathione-regulated potassium exporter activity
INE92_RS22610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
INE92_RS22615	COG1136	(ABC) transporter
INE92_RS22625	COG0733	neurotransmitter:sodium symporter activity
INE92_RS22635	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INE92_RS22640	COG0784	Response regulator, receiver
INE92_RS22640	COG5002	protein histidine kinase activity
INE92_RS22645	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
INE92_RS22650	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
INE92_RS22670	COG1082	Xylose isomerase domain protein TIM barrel
INE92_RS22695	COG1346	cytolysis
INE92_RS22700	COG1380	Effector of murein hydrolase LrgA
INE92_RS22705	COG0280	phosphate acetyltransferase
INE92_RS22710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
INE92_RS22725	COG1216	Glycosyl transferase, family 2
INE92_RS22725	COG0463	Glycosyl transferase, family 2
INE92_RS22730	COG2003	Belongs to the UPF0758 family
INE92_RS22760	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
INE92_RS22765	COG4206	TonB-dependent receptor
INE92_RS22765	COG1629	transport
INE92_RS22770	COG1082	Xylose isomerase domain protein TIM barrel
INE92_RS22775	COG0366	Alpha amylase catalytic
INE92_RS22785	COG1785	Belongs to the alkaline phosphatase family
INE92_RS22790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
INE92_RS22795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
INE92_RS22800	COG2815	serine threonine protein kinase
INE92_RS22800	COG0515	serine threonine protein kinase
INE92_RS22805	COG0564	pseudouridine synthase activity
INE92_RS22830	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INE92_RS22835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
INE92_RS22840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
INE92_RS22845	COG0436	Aminotransferase
INE92_RS22855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
INE92_RS22870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
INE92_RS22875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
INE92_RS22885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INE92_RS22885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
INE92_RS22890	COG2890	protein-(glutamine-N5) methyltransferase activity
INE92_RS22900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
INE92_RS22910	COG0165	Argininosuccinate lyase
INE92_RS22965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INE92_RS23005	COG4206	TonB-dependent receptor
INE92_RS23005	COG1629	transport
INE92_RS23050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
INE92_RS23055	COG1396	sequence-specific DNA binding
INE92_RS23055	COG1917	Cupin 2, conserved barrel domain protein
INE92_RS23065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
INE92_RS23075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
INE92_RS23080	COG0137	argininosuccinate synthase activity
INE92_RS23090	COG1438	arginine binding
INE92_RS23095	COG1070	Carbohydrate kinase
INE92_RS23100	COG4806	L-rhamnose isomerase
INE92_RS23110	COG0235	Class ii aldolase
INE92_RS23115	COG1454	alcohol dehydrogenase
INE92_RS23125	COG3292	Two component regulator propeller
INE92_RS23125	COG2205	protein histidine kinase activity
INE92_RS23125	COG0745	RESPONSE REGULATOR receiver
INE92_RS23130	COG4771	TonB-dependent receptor
INE92_RS23135	COG0702	epimerase
INE92_RS23165	COG1501	Belongs to the glycosyl hydrolase 31 family
INE92_RS23170	COG3250	beta-galactosidase activity
INE92_RS23215	COG0564	pseudouridine synthase activity
INE92_RS23245	COG3537	Alpha-1,2-mannosidase
INE92_RS23250	COG0745	RESPONSE REGULATOR receiver
INE92_RS23250	COG2205	protein histidine kinase activity
INE92_RS23250	COG3292	Two component regulator propeller
INE92_RS23270	COG4771	TonB-dependent receptor
INE92_RS23295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INE92_RS23295	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INE92_RS23300	COG0612	Peptidase, M16
INE92_RS23305	COG0534	Mate efflux family protein
INE92_RS23310	COG2205	protein histidine kinase activity
INE92_RS23310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INE92_RS23315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INE92_RS23335	COG0488	(ABC) transporter
INE92_RS23340	COG3590	peptidase
INE92_RS23345	COG0138	bifunctional purine biosynthesis protein purh
INE92_RS23370	COG0772	Belongs to the SEDS family
INE92_RS23380	COG1774	PSP1 C-terminal conserved region
INE92_RS23385	COG0470	DNA polymerase III
INE92_RS23390	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
INE92_RS23395	COG2193	ferroxidase activity
INE92_RS23470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INE92_RS23475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
INE92_RS23480	COG1160	GTP binding
INE92_RS23490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
INE92_RS23495	COG1127	ABC transporter
INE92_RS23500	COG0724	RNA recognition motif
INE92_RS23505	COG0544	peptidyl-prolyl cis-trans isomerase activity
INE92_RS23510	COG0740	serine-type endopeptidase activity
INE92_RS23515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
INE92_RS23520	COG0514	ATP-dependent DNA helicase (RecQ)
INE92_RS23525	COG0516	GMP reductase activity
INE92_RS23525	COG0517	IMP dehydrogenase activity
INE92_RS23530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INE92_RS23540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
INE92_RS23555	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
INE92_RS23595	COG3022	response to hydroperoxide
INE92_RS23600	COG0110	maltose O-acetyltransferase activity
INE92_RS23620	COG1187	pseudouridine synthase activity
INE92_RS23625	COG0017	Asparaginyl-tRNA synthetase
INE92_RS23635	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS23640	COG2205	protein histidine kinase activity
INE92_RS23640	COG3292	Two component regulator propeller
INE92_RS23640	COG0745	RESPONSE REGULATOR receiver
INE92_RS23685	COG4771	TonB-dependent receptor
INE92_RS23690	COG0702	epimerase
INE92_RS23695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
INE92_RS23700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
INE92_RS23705	COG0052	Belongs to the universal ribosomal protein uS2 family
INE92_RS23710	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
INE92_RS23725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
INE92_RS23730	COG0179	Fumarylacetoacetate (FAA) hydrolase
INE92_RS23735	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
INE92_RS23750	COG0482	sulfurtransferase activity
INE92_RS23760	COG1570	exodeoxyribonuclease VII activity
INE92_RS23770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INE92_RS23780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
INE92_RS23785	COG0489	protein tyrosine kinase activity
INE92_RS23790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INE92_RS23795	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
INE92_RS23830	COG0039	L-malate dehydrogenase activity
INE92_RS23850	COG4771	TonB-dependent receptor
INE92_RS23885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
INE92_RS23890	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
INE92_RS23895	COG0811	peptide transport
INE92_RS23900	COG0848	biopolymer transport protein
INE92_RS23915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
INE92_RS23920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INE92_RS23925	COG0105	UTP biosynthetic process
INE92_RS23930	COG0739	heme binding
INE92_RS23945	COG0149	triose-phosphate isomerase activity
INE92_RS23955	COG0302	gtp cyclohydrolase
INE92_RS23960	COG0358	DNA primase activity
INE92_RS23970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
INE92_RS23995	COG0514	ATP-dependent DNA helicase (RecQ)
INE92_RS24000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INE92_RS24000	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
INE92_RS24015	COG4771	TonB-dependent receptor
INE92_RS24020	COG0702	epimerase
INE92_RS24050	COG1785	Belongs to the alkaline phosphatase family
INE92_RS24065	COG0009	L-threonylcarbamoyladenylate synthase
INE92_RS24075	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
INE92_RS24080	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
INE92_RS24085	COG0658	competence protein
INE92_RS24085	COG2333	competence protein COMEC
INE92_RS24090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
INE92_RS24100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INE92_RS24110	COG4771	TonB-dependent receptor
INE92_RS24120	COG3537	Alpha-1,2-mannosidase
INE92_RS24125	COG3537	Alpha-1,2-mannosidase
INE92_RS24135	COG3537	Alpha-1,2-mannosidase
INE92_RS24140	COG4948	Mandelate Racemase Muconate Lactonizing
INE92_RS24155	COG3279	Response regulator of the LytR AlgR family
INE92_RS24160	COG3275	phosphorelay sensor kinase activity
INE92_RS24175	COG0386	Belongs to the glutathione peroxidase family
INE92_RS24185	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INE92_RS24260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INE92_RS24270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
INE92_RS24285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INE92_RS24290	COG0742	ribosomal rna small subunit methyltransferase
INE92_RS24335	COG4206	TonB-dependent receptor
INE92_RS24335	COG1629	transport
INE92_RS24375	COG3537	Alpha-1,2-mannosidase
INE92_RS24395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
INE92_RS24400	COG0739	heme binding
INE92_RS24410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INE92_RS24415	COG1388	LysM domain
INE92_RS24415	COG0741	lytic transglycosylase activity
INE92_RS24425	COG1475	DNA binding
INE92_RS24430	COG1192	Involved in chromosome partitioning
INE92_RS24435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
INE92_RS24440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE92_RS24450	COG4589	Belongs to the CDS family
INE92_RS24455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INE92_RS24470	COG1196	nuclear chromosome segregation
INE92_RS24475	COG2239	Acts as a magnesium transporter
INE92_RS24480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
INE92_RS24490	COG2195	Cleaves the N-terminal amino acid of tripeptides
INE92_RS24530	COG0668	transmembrane transport
INE92_RS24535	COG0662	Cupin 2, conserved barrel domain protein
INE92_RS24535	COG2207	Transcriptional regulator
INE92_RS24565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE92_RS24570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INE92_RS24575	COG0713	ATP synthesis coupled electron transport
INE92_RS24590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
INE92_RS24595	COG0649	NAD binding
INE92_RS24595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE92_RS24600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE92_RS24605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INE92_RS24640	COG3250	beta-galactosidase activity
INE92_RS24650	COG3250	beta-galactosidase activity
INE92_RS24655	COG3940	Belongs to the glycosyl hydrolase 43 family
INE92_RS24665	COG0702	epimerase
INE92_RS24680	COG4771	TonB-dependent receptor
INE92_RS24685	COG0702	epimerase
INE92_RS24690	COG1629	transport
INE92_RS24690	COG4206	TonB-dependent receptor
INE92_RS24710	COG3537	Alpha-1,2-mannosidase
INE92_RS24725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INE92_RS24730	COG0569	domain protein
INE92_RS24735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INE92_RS24750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INE92_RS24755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
INE92_RS24760	COG0805	protein transport
INE92_RS24770	COG2271	Major facilitator Superfamily
INE92_RS24775	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
INE92_RS24780	COG3775	system Galactitol-specific IIC component
INE92_RS24785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS24810	COG2755	lipolytic protein G-D-S-L family
INE92_RS24820	COG0745	RESPONSE REGULATOR receiver
INE92_RS24820	COG2205	protein histidine kinase activity
INE92_RS24820	COG3292	Two component regulator propeller
INE92_RS24830	COG0702	epimerase
INE92_RS24835	COG4771	TonB-dependent receptor
INE92_RS24855	COG3279	Response regulator of the LytR AlgR family
INE92_RS24860	COG1242	4 iron, 4 sulfur cluster binding
INE92_RS24870	COG0363	glucosamine-6-phosphate deaminase activity
INE92_RS24875	COG0009	L-threonylcarbamoyladenylate synthase
INE92_RS24885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INE92_RS24890	COG0561	phosphatase activity
INE92_RS24895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
INE92_RS24920	COG2755	lipolytic protein G-D-S-L family
INE92_RS24950	COG0702	epimerase
INE92_RS24955	COG1629	transport
INE92_RS24980	COG4771	TonB-dependent receptor
INE92_RS24990	COG1629	transport
INE92_RS25000	COG3401	FG-GAP repeat protein
INE92_RS25015	COG2755	lipolytic protein G-D-S-L family
INE92_RS25025	COG3401	FG-GAP repeat protein
INE92_RS25035	COG3254	rhamnose metabolic process
INE92_RS25040	COG0745	RESPONSE REGULATOR receiver
INE92_RS25040	COG2205	protein histidine kinase activity
INE92_RS25040	COG0745	RESPONSE REGULATOR receiver
INE92_RS25040	COG2205	protein histidine kinase activity
INE92_RS25040	COG3292	Two component regulator propeller
INE92_RS25040	COG3292	Two component regulator propeller
INE92_RS25060	COG3250	beta-galactosidase activity
INE92_RS25065	COG3401	FG-GAP repeat protein
INE92_RS25095	COG2205	protein histidine kinase activity
INE92_RS25095	COG0745	RESPONSE REGULATOR receiver
INE92_RS25095	COG3292	Two component regulator propeller
INE92_RS25100	COG1629	transport
INE92_RS25125	COG3401	FG-GAP repeat protein
INE92_RS25140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INE92_RS25160	COG4771	TonB-dependent receptor
INE92_RS25165	COG0702	epimerase
INE92_RS25180	COG4771	TonB-dependent receptor
INE92_RS25270	COG2205	protein histidine kinase activity
INE92_RS25270	COG3292	Two component regulator propeller
INE92_RS25270	COG0745	RESPONSE REGULATOR receiver
INE92_RS25270	COG3292	Two component regulator propeller
INE92_RS25270	COG2205	protein histidine kinase activity
INE92_RS25270	COG0745	RESPONSE REGULATOR receiver
INE92_RS25290	COG0546	phosphoglycolate phosphatase activity
INE92_RS25320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
INE92_RS25330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INE92_RS25340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
INE92_RS25345	COG1506	peptidase
INE92_RS25345	COG0823	Involved in the tonB-independent uptake of proteins
INE92_RS25365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
INE92_RS25380	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
INE92_RS25380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INE92_RS25385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
INE92_RS25390	COG1078	dGTPase activity
INE92_RS25395	COG0284	orotidine-5'-phosphate decarboxylase activity
INE92_RS25400	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
INE92_RS25405	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
INE92_RS25410	COG1704	LemA family
INE92_RS25435	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
INE92_RS25440	COG2226	methyltransferase
INE92_RS25445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
INE92_RS25450	COG1702	phosphate starvation-inducible protein PhoH
INE92_RS25475	COG2268	Band 7 protein
INE92_RS25485	COG0101	tRNA pseudouridine synthase activity
INE92_RS25505	COG3250	beta-galactosidase activity
INE92_RS25510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INE92_RS25515	COG0673	inositol 2-dehydrogenase activity
INE92_RS25565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
INE92_RS25575	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
INE92_RS25590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INE92_RS25595	COG0793	Belongs to the peptidase S41A family
INE92_RS25600	COG2131	deaminase
INE92_RS25610	COG0339	signal peptide processing
INE92_RS25620	COG1970	mechanosensitive ion channel activity
INE92_RS25625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
INE92_RS25625	COG0519	Catalyzes the synthesis of GMP from XMP
INE92_RS25655	COG1629	transport
INE92_RS25660	COG0561	phosphatase activity
INE92_RS25695	COG0297	glycogen (starch) synthase activity
INE92_RS25710	COG0297	glycogen (starch) synthase activity
INE92_RS25715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
INE92_RS25720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
INE92_RS25725	COG0543	2 iron, 2 sulfur cluster binding
INE92_RS25730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
INE92_RS25735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
INE92_RS25740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
INE92_RS25755	COG0791	NLP P60 protein
INE92_RS25770	COG0612	Peptidase, M16
INE92_RS25775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
INE92_RS25780	COG1597	lipid kinase activity
INE92_RS25785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
INE92_RS25800	COG1136	(ABC) transporter
INE92_RS25820	COG2211	Major facilitator Superfamily
INE92_RS25825	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INE92_RS25840	COG1674	ftsk spoiiie
INE92_RS25850	COG0492	ferredoxin-NADP+ reductase activity
INE92_RS25855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INE92_RS25895	COG4206	TonB-dependent receptor
INE92_RS25895	COG1629	transport
INE92_RS25950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE92_RS25950	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
INE92_RS25960	COG1234	tRNA 3'-trailer cleavage
INE92_RS25965	COG2989	Protein conserved in bacteria
INE92_RS25985	COG3956	TIGRFAM MazG family protein
INE92_RS26055	COG3177	Filamentation induced by cAMP protein fic
INE92_RS26060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INE92_RS26075	COG1192	Involved in chromosome partitioning
INE92_RS26125	COG1196	nuclear chromosome segregation
INE92_RS26125	COG0741	lytic transglycosylase activity
INE92_RS26125	COG0739	heme binding
INE92_RS26245	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
INE92_RS26245	COG0662	Cupin 2, conserved barrel domain protein
INE92_RS26260	COG1216	Glycosyl transferase, family 2
INE92_RS26260	COG1442	glycosyl transferase family 8
INE92_RS26270	COG0438	transferase activity, transferring glycosyl groups
INE92_RS26300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
INE92_RS26305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
INE92_RS26425	COG1192	Involved in chromosome partitioning
INE92_RS26440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
INE92_RS26445	COG0784	Response regulator, receiver
INE92_RS26445	COG2205	protein histidine kinase activity
INE92_RS26460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
INE92_RS26470	COG0656	L-ascorbic acid biosynthetic process
INE92_RS26505	COG2003	Belongs to the UPF0758 family
INE92_RS26540	COG2337	Toxic component of a toxin-antitoxin (TA) module
INE92_RS26550	COG0776	regulation of translation
INE92_RS26615	COG4474	Belongs to the UPF0398 family
INE92_RS26620	COG3385	transposase activity
INE92_RS26710	COG0629	single-stranded DNA binding
INE92_RS26840	COG4771	TonB-dependent receptor
INE92_RS26985	COG3023	N-Acetylmuramoyl-L-alanine amidase
INE92_RS27010	COG3292	Two component regulator propeller
INE92_RS27010	COG2205	protein histidine kinase activity
INE92_RS27010	COG0745	RESPONSE REGULATOR receiver