locus-tag	class	description
FKZ68_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKZ68_RS00010	COG0778	Nitroreductase
FKZ68_RS00020	COG1640	4-alpha-glucanotransferase
FKZ68_RS00040	COG1216	Glycosyl transferase, family 2
FKZ68_RS00050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKZ68_RS00055	COG1022	Amp-dependent synthetase and ligase
FKZ68_RS00095	COG0359	binds to the 23S rRNA
FKZ68_RS00100	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FKZ68_RS00105	COG0360	Binds together with S18 to 16S ribosomal RNA
FKZ68_RS00125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKZ68_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKZ68_RS00170	COG2431	L-lysine efflux transmembrane transporter activity
FKZ68_RS00215	COG1373	ATPase (AAA superfamily
FKZ68_RS00220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FKZ68_RS00240	COG2234	aminopeptidase activity
FKZ68_RS00250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FKZ68_RS00255	COG0802	atpase or kinase
FKZ68_RS00270	COG0714	Associated with various cellular activities
FKZ68_RS00305	COG3118	belongs to the thioredoxin family
FKZ68_RS00315	COG0688	phosphatidylethanolamine metabolic process
FKZ68_RS00320	COG1183	phosphatidylcholine synthase activity
FKZ68_RS00340	COG0792	nuclease activity
FKZ68_RS00365	COG0534	Mate efflux family protein
FKZ68_RS00370	COG0528	UMP kinase activity
FKZ68_RS00385	COG3250	beta-galactosidase activity
FKZ68_RS00395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKZ68_RS00400	COG1629	transport
FKZ68_RS00400	COG4206	TonB-dependent receptor
FKZ68_RS00405	COG3292	Two component regulator propeller
FKZ68_RS00405	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS00405	COG2205	protein histidine kinase activity
FKZ68_RS00415	COG0233	cytoplasmic translational termination
FKZ68_RS00420	COG1162	GTPase activity
FKZ68_RS00430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKZ68_RS00445	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FKZ68_RS00445	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FKZ68_RS00460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKZ68_RS00470	COG1629	transport
FKZ68_RS00470	COG4206	TonB-dependent receptor
FKZ68_RS00475	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS00480	COG1629	transport
FKZ68_RS00495	COG2095	MarC family integral membrane protein
FKZ68_RS00510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKZ68_RS00520	COG1435	thymidine kinase activity
FKZ68_RS00525	COG0628	permease
FKZ68_RS00565	COG1396	sequence-specific DNA binding
FKZ68_RS00575	COG4771	TonB-dependent receptor
FKZ68_RS00625	COG2076	Multidrug Resistance protein
FKZ68_RS00640	COG0589	response to stress
FKZ68_RS00640	COG0475	glutathione-regulated potassium exporter activity
FKZ68_RS00665	COG2207	Transcriptional regulator
FKZ68_RS00680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKZ68_RS00685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKZ68_RS00725	COG1522	sequence-specific DNA binding
FKZ68_RS00730	COG2873	o-acetylhomoserine
FKZ68_RS00740	COG0668	transmembrane transport
FKZ68_RS00770	COG4771	TonB-dependent receptor
FKZ68_RS00810	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FKZ68_RS00815	COG0527	aspartate kinase activity
FKZ68_RS00815	COG0460	homoserine dehydrogenase
FKZ68_RS00825	COG0252	asparaginase activity
FKZ68_RS00845	COG1106	Psort location Cytoplasmic, score
FKZ68_RS00850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FKZ68_RS00855	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FKZ68_RS00870	COG4771	TonB-dependent receptor
FKZ68_RS00885	COG0826	peptidase U32
FKZ68_RS00890	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FKZ68_RS00905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FKZ68_RS00925	COG0519	Catalyzes the synthesis of GMP from XMP
FKZ68_RS00935	COG3385	transposase activity
FKZ68_RS00945	COG4771	TonB-dependent receptor
FKZ68_RS00985	COG1131	(ABC) transporter
FKZ68_RS01000	COG5002	protein histidine kinase activity
FKZ68_RS01005	COG2205	protein histidine kinase activity
FKZ68_RS01015	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FKZ68_RS01020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FKZ68_RS01025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FKZ68_RS01045	COG3387	PFAM Glycoside hydrolase 15-related
FKZ68_RS01105	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS01135	COG4771	TonB-dependent receptor
FKZ68_RS01150	COG0471	metal ion transport
FKZ68_RS01160	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS01160	COG3292	Two component regulator propeller
FKZ68_RS01160	COG2205	protein histidine kinase activity
FKZ68_RS01160	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS01160	COG3292	Two component regulator propeller
FKZ68_RS01160	COG2205	protein histidine kinase activity
FKZ68_RS01185	COG0702	epimerase
FKZ68_RS01190	COG4771	TonB-dependent receptor
FKZ68_RS01210	COG0616	signal peptide processing
FKZ68_RS01215	COG1663	tetraacyldisaccharide 4'-kinase activity
FKZ68_RS01220	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FKZ68_RS01225	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FKZ68_RS01250	COG0513	Belongs to the DEAD box helicase family
FKZ68_RS01255	COG2070	2-Nitropropane dioxygenase
FKZ68_RS01260	COG0724	RNA recognition motif
FKZ68_RS01275	COG3973	AAA domain
FKZ68_RS01290	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS01305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKZ68_RS01350	COG2885	chlorophyll binding
FKZ68_RS01440	COG2204	response regulator
FKZ68_RS01445	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKZ68_RS01465	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS01470	COG0737	Belongs to the 5'-nucleotidase family
FKZ68_RS01475	COG0737	Belongs to the 5'-nucleotidase family
FKZ68_RS01480	COG0335	large ribosomal subunit rRNA binding
FKZ68_RS01490	COG1136	(ABC) transporter
FKZ68_RS01490	COG0577	efflux transmembrane transporter activity
FKZ68_RS01495	COG0577	efflux transmembrane transporter activity
FKZ68_RS01495	COG1136	(ABC) transporter
FKZ68_RS01500	COG0577	efflux transmembrane transporter activity
FKZ68_RS01500	COG1136	(ABC) transporter
FKZ68_RS01510	COG1538	Outer membrane efflux protein
FKZ68_RS01515	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKZ68_RS01515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKZ68_RS01525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKZ68_RS01540	COG2996	Protein conserved in bacteria
FKZ68_RS01545	COG0039	L-malate dehydrogenase activity
FKZ68_RS01555	COG2217	Heavy metal translocating P-type atpase
FKZ68_RS01580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FKZ68_RS01585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKZ68_RS01590	COG0509	glycine decarboxylation via glycine cleavage system
FKZ68_RS01605	COG0006	proline dipeptidase activity
FKZ68_RS01610	COG3458	cephalosporin-C deacetylase activity
FKZ68_RS01625	COG1283	sodium-dependent phosphate transmembrane transporter activity
FKZ68_RS01630	COG1773	rubredoxin
FKZ68_RS01640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FKZ68_RS01645	COG1011	Hydrolase
FKZ68_RS01650	COG0196	riboflavin kinase activity
FKZ68_RS01655	COG1266	CAAX protease self-immunity
FKZ68_RS01660	COG2166	iron-sulfur cluster assembly
FKZ68_RS01665	COG2234	aminopeptidase activity
FKZ68_RS01670	COG1619	proteins homologs of microcin C7 resistance protein MccF
FKZ68_RS01675	COG0280	phosphate acetyltransferase
FKZ68_RS01680	COG3426	butyrate kinase activity
FKZ68_RS01705	COG1185	polyribonucleotide nucleotidyltransferase activity
FKZ68_RS01715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKZ68_RS01745	COG0076	glutamate decarboxylase activity
FKZ68_RS01750	COG2066	Belongs to the glutaminase family
FKZ68_RS01760	COG0531	amino acid
FKZ68_RS01790	COG3345	alpha-galactosidase
FKZ68_RS01810	COG1131	(ABC) transporter
FKZ68_RS01900	COG0667	Aldo Keto reductase
FKZ68_RS01945	COG1696	Membrane protein involved in D-alanine export
FKZ68_RS01985	COG1309	transcriptional regulator
FKZ68_RS01990	COG2986	histidine ammonia-lyase
FKZ68_RS02000	COG1228	amidohydrolase
FKZ68_RS02010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FKZ68_RS02020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FKZ68_RS02030	COG3385	transposase activity
FKZ68_RS02040	COG0203	ribosomal protein L17
FKZ68_RS02045	COG0202	RNA polymerase activity
FKZ68_RS02050	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FKZ68_RS02055	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FKZ68_RS02060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FKZ68_RS02065	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FKZ68_RS02070	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKZ68_RS02085	COG0200	Binds to the 23S rRNA
FKZ68_RS02090	COG1841	ribosomal large subunit assembly
FKZ68_RS02095	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FKZ68_RS02100	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FKZ68_RS02105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKZ68_RS02110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FKZ68_RS02115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FKZ68_RS02120	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FKZ68_RS02125	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FKZ68_RS02130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FKZ68_RS02135	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKZ68_RS02140	COG0255	Belongs to the universal ribosomal protein uL29 family
FKZ68_RS02145	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FKZ68_RS02150	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKZ68_RS02155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FKZ68_RS02160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FKZ68_RS02165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKZ68_RS02170	COG0089	rRNA binding
FKZ68_RS02175	COG0088	Forms part of the polypeptide exit tunnel
FKZ68_RS02180	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKZ68_RS02185	COG0051	transcription antitermination factor activity, RNA binding
FKZ68_RS02190	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKZ68_RS02195	COG0049	tRNA binding
FKZ68_RS02200	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FKZ68_RS02210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKZ68_RS02215	COG0085	RNA polymerase activity
FKZ68_RS02220	COG0222	ribosome binding
FKZ68_RS02225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKZ68_RS02230	COG0081	regulation of translation
FKZ68_RS02235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKZ68_RS02245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKZ68_RS02255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKZ68_RS02285	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS02290	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FKZ68_RS02300	COG0006	proline dipeptidase activity
FKZ68_RS02305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FKZ68_RS02315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKZ68_RS02325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKZ68_RS02335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FKZ68_RS02365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKZ68_RS02370	COG1027	Aspartate ammonia-lyase
FKZ68_RS02375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FKZ68_RS02380	COG0252	asparaginase activity
FKZ68_RS02395	COG2096	Adenosyltransferase
FKZ68_RS02470	COG0631	protein serine/threonine phosphatase activity
FKZ68_RS02480	COG0515	serine threonine protein kinase
FKZ68_RS02510	COG3152	Membrane
FKZ68_RS02520	COG3385	transposase activity
FKZ68_RS02545	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS02550	COG4804	nuclease activity
FKZ68_RS02575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKZ68_RS02615	COG0358	DNA primase activity
FKZ68_RS02660	COG0662	Cupin 2, conserved barrel domain protein
FKZ68_RS02660	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FKZ68_RS02665	COG0318	PFAM AMP-dependent synthetase and ligase
FKZ68_RS02670	COG1396	sequence-specific DNA binding
FKZ68_RS02675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FKZ68_RS02690	COG2059	Chromate
FKZ68_RS02710	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FKZ68_RS02715	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKZ68_RS02745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FKZ68_RS02750	COG5002	protein histidine kinase activity
FKZ68_RS02750	COG2205	protein histidine kinase activity
FKZ68_RS02750	COG0784	Response regulator, receiver
FKZ68_RS02755	COG0793	Belongs to the peptidase S41A family
FKZ68_RS02760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKZ68_RS02785	COG1040	competence protein
FKZ68_RS02830	COG2610	gluconate transmembrane transporter activity
FKZ68_RS02835	COG1929	Belongs to the glycerate kinase type-1 family
FKZ68_RS02855	COG1629	transport
FKZ68_RS02865	COG1609	Transcriptional regulator
FKZ68_RS02870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKZ68_RS02875	COG4206	TonB-dependent receptor
FKZ68_RS02875	COG1629	transport
FKZ68_RS02965	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS03025	COG0740	serine-type endopeptidase activity
FKZ68_RS03180	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FKZ68_RS03195	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FKZ68_RS03220	COG4771	TonB-dependent receptor
FKZ68_RS03225	COG3292	Two component regulator propeller
FKZ68_RS03225	COG2205	protein histidine kinase activity
FKZ68_RS03225	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS03235	COG3634	alkyl hydroperoxide reductase activity
FKZ68_RS03245	COG2816	NAD+ diphosphatase activity
FKZ68_RS03275	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS03295	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FKZ68_RS03330	COG0561	phosphatase activity
FKZ68_RS03335	COG4771	TonB-dependent receptor
FKZ68_RS03360	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS03360	COG2205	protein histidine kinase activity
FKZ68_RS03360	COG3292	Two component regulator propeller
FKZ68_RS03380	COG0018	arginyl-trna synthetase
FKZ68_RS03390	COG0705	Rhomboid family
FKZ68_RS03405	COG0339	signal peptide processing
FKZ68_RS03410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKZ68_RS03420	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FKZ68_RS03420	COG0674	pyruvate-flavodoxin oxidoreductase activity
FKZ68_RS03425	COG1013	pyruvate-flavodoxin oxidoreductase activity
FKZ68_RS03450	COG3250	beta-galactosidase activity
FKZ68_RS03455	COG3458	cephalosporin-C deacetylase activity
FKZ68_RS03460	COG3345	alpha-galactosidase
FKZ68_RS03465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKZ68_RS03470	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS03505	COG4771	TonB-dependent receptor
FKZ68_RS03520	COG4591	ABC-type transport system involved in lipoprotein release permease component
FKZ68_RS03525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FKZ68_RS03545	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS03560	COG0606	chelatase, subunit chli
FKZ68_RS03565	COG2205	protein histidine kinase activity
FKZ68_RS03585	COG3250	beta-galactosidase activity
FKZ68_RS03615	COG0702	epimerase
FKZ68_RS03620	COG1629	transport
FKZ68_RS03630	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS03670	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS03680	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS03685	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS03690	COG3292	Two component regulator propeller
FKZ68_RS03690	COG2205	protein histidine kinase activity
FKZ68_RS03690	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS03705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKZ68_RS03705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKZ68_RS03720	COG3475	LICD family
FKZ68_RS03735	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS03765	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FKZ68_RS03770	COG0545	Peptidyl-prolyl cis-trans isomerase
FKZ68_RS03775	COG0545	Peptidyl-prolyl cis-trans isomerase
FKZ68_RS03840	COG2003	Belongs to the UPF0758 family
FKZ68_RS03845	COG0582	viral genome integration into host DNA
FKZ68_RS03870	COG0561	phosphatase activity
FKZ68_RS03945	COG4771	TonB-dependent receptor
FKZ68_RS03950	COG0702	epimerase
FKZ68_RS03960	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FKZ68_RS03970	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FKZ68_RS03980	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FKZ68_RS03985	COG2211	Major facilitator Superfamily
FKZ68_RS03990	COG3408	Glycogen debranching enzyme
FKZ68_RS04025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FKZ68_RS04030	COG3409	Peptidoglycan-binding domain 1 protein
FKZ68_RS04030	COG0793	Belongs to the peptidase S41A family
FKZ68_RS04060	COG0561	phosphatase activity
FKZ68_RS04065	COG4206	TonB-dependent receptor
FKZ68_RS04065	COG1629	transport
FKZ68_RS04070	COG3292	Two component regulator propeller
FKZ68_RS04070	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04070	COG2205	protein histidine kinase activity
FKZ68_RS04095	COG1053	succinate dehydrogenase
FKZ68_RS04100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FKZ68_RS04170	COG0758	DNA mediated transformation
FKZ68_RS04180	COG0826	peptidase U32
FKZ68_RS04185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKZ68_RS04210	COG1629	transport
FKZ68_RS04210	COG4206	TonB-dependent receptor
FKZ68_RS04250	COG0557	exoribonuclease II activity
FKZ68_RS04260	COG5002	protein histidine kinase activity
FKZ68_RS04270	COG1629	transport
FKZ68_RS04270	COG4206	TonB-dependent receptor
FKZ68_RS04285	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS04290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FKZ68_RS04325	COG3254	rhamnose metabolic process
FKZ68_RS04330	COG0702	epimerase
FKZ68_RS04335	COG4771	TonB-dependent receptor
FKZ68_RS04345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS04350	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04350	COG2205	protein histidine kinase activity
FKZ68_RS04350	COG3292	Two component regulator propeller
FKZ68_RS04375	COG0702	epimerase
FKZ68_RS04380	COG1629	transport
FKZ68_RS04395	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FKZ68_RS04400	COG2205	protein histidine kinase activity
FKZ68_RS04400	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04400	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04400	COG3292	Two component regulator propeller
FKZ68_RS04400	COG2205	protein histidine kinase activity
FKZ68_RS04400	COG3292	Two component regulator propeller
FKZ68_RS04425	COG0702	epimerase
FKZ68_RS04430	COG4771	TonB-dependent receptor
FKZ68_RS04505	COG4206	TonB-dependent receptor
FKZ68_RS04505	COG1629	transport
FKZ68_RS04515	COG4206	TonB-dependent receptor
FKZ68_RS04515	COG1629	transport
FKZ68_RS04540	COG3119	arylsulfatase activity
FKZ68_RS04560	COG2814	Major facilitator Superfamily
FKZ68_RS04575	COG4206	TonB-dependent receptor
FKZ68_RS04575	COG1629	transport
FKZ68_RS04595	COG0012	GTP binding
FKZ68_RS04600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKZ68_RS04605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKZ68_RS04610	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FKZ68_RS04635	COG4771	TonB-dependent receptor
FKZ68_RS04640	COG3537	Alpha-1,2-mannosidase
FKZ68_RS04650	COG1785	Belongs to the alkaline phosphatase family
FKZ68_RS04670	COG3250	beta-galactosidase activity
FKZ68_RS04675	COG0495	leucyl-tRNA aminoacylation
FKZ68_RS04680	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKZ68_RS04685	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FKZ68_RS04690	COG1360	Flagellar Motor Protein
FKZ68_RS04700	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FKZ68_RS04735	COG1629	transport
FKZ68_RS04735	COG4206	TonB-dependent receptor
FKZ68_RS04765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKZ68_RS04765	COG0731	radical SAM domain protein
FKZ68_RS04780	COG0784	Response regulator, receiver
FKZ68_RS04780	COG2198	Histidine kinase
FKZ68_RS04780	COG2205	protein histidine kinase activity
FKZ68_RS04780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKZ68_RS04790	COG1629	transport
FKZ68_RS04810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS04865	COG3292	Two component regulator propeller
FKZ68_RS04865	COG2205	protein histidine kinase activity
FKZ68_RS04865	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04865	COG2205	protein histidine kinase activity
FKZ68_RS04865	COG3292	Two component regulator propeller
FKZ68_RS04865	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS04900	COG4206	TonB-dependent receptor
FKZ68_RS04900	COG1629	transport
FKZ68_RS04915	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS04920	COG0659	secondary active sulfate transmembrane transporter activity
FKZ68_RS04925	COG1592	Rubrerythrin
FKZ68_RS04950	COG2027	D-alanyl-D-alanine carboxypeptidase
FKZ68_RS04960	COG0427	acetyl-CoA hydrolase
FKZ68_RS04970	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKZ68_RS04995	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS05065	COG2177	Part of the ABC transporter FtsEX involved in
FKZ68_RS05075	COG1968	undecaprenyl-diphosphatase activity
FKZ68_RS05080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FKZ68_RS05085	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FKZ68_RS05090	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FKZ68_RS05090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKZ68_RS05100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FKZ68_RS05135	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FKZ68_RS05145	COG0656	L-ascorbic acid biosynthetic process
FKZ68_RS05180	COG0582	viral genome integration into host DNA
FKZ68_RS05200	COG0594	ribonuclease P activity
FKZ68_RS05205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FKZ68_RS05215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKZ68_RS05240	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FKZ68_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
FKZ68_RS05295	COG0726	polysaccharide deacetylase
FKZ68_RS05315	COG1121	(ABC) transporter
FKZ68_RS05325	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FKZ68_RS05325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKZ68_RS05330	COG1238	metal cluster binding
FKZ68_RS05345	COG0823	Involved in the tonB-independent uptake of proteins
FKZ68_RS05345	COG1506	peptidase
FKZ68_RS05355	COG0116	Belongs to the methyltransferase superfamily
FKZ68_RS05355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKZ68_RS05360	COG1045	serine acetyltransferase
FKZ68_RS05370	COG3279	Response regulator of the LytR AlgR family
FKZ68_RS05385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKZ68_RS05385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKZ68_RS05390	COG0142	geranyltranstransferase activity
FKZ68_RS05405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FKZ68_RS05410	COG1694	Mazg nucleotide pyrophosphohydrolase
FKZ68_RS05415	COG1490	D-aminoacyl-tRNA deacylase activity
FKZ68_RS05420	COG0322	excinuclease ABC activity
FKZ68_RS05425	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKZ68_RS05430	COG0445	tRNA wobble uridine modification
FKZ68_RS05455	COG4771	TonB-dependent receptor
FKZ68_RS05495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FKZ68_RS05500	COG2715	membrane protein required for spore maturation
FKZ68_RS05505	COG2255	four-way junction helicase activity
FKZ68_RS05525	COG3591	Belongs to the peptidase S1B family
FKZ68_RS05550	COG0702	epimerase
FKZ68_RS05555	COG4206	TonB-dependent receptor
FKZ68_RS05555	COG1629	transport
FKZ68_RS05565	COG3292	Two component regulator propeller
FKZ68_RS05565	COG2205	protein histidine kinase activity
FKZ68_RS05565	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS05570	COG0513	Belongs to the DEAD box helicase family
FKZ68_RS05575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKZ68_RS05590	COG0612	Peptidase, M16
FKZ68_RS05600	COG0584	glycerophosphoryl diester phosphodiesterase
FKZ68_RS05620	COG4771	TonB-dependent receptor
FKZ68_RS05630	COG1595	DNA-templated transcription, initiation
FKZ68_RS05660	COG1629	transport
FKZ68_RS05660	COG4206	TonB-dependent receptor
FKZ68_RS05685	COG0584	glycerophosphoryl diester phosphodiesterase
FKZ68_RS05700	COG4771	TonB-dependent receptor
FKZ68_RS05705	COG0702	epimerase
FKZ68_RS05720	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS05765	COG0681	Belongs to the peptidase S26 family
FKZ68_RS05775	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FKZ68_RS05840	COG1215	transferase activity, transferring glycosyl groups
FKZ68_RS05860	COG5492	domain, Protein
FKZ68_RS05870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKZ68_RS05880	COG0702	epimerase
FKZ68_RS05885	COG4771	TonB-dependent receptor
FKZ68_RS05890	COG3119	arylsulfatase activity
FKZ68_RS05895	COG2205	protein histidine kinase activity
FKZ68_RS05895	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS05895	COG3292	Two component regulator propeller
FKZ68_RS05895	COG2205	protein histidine kinase activity
FKZ68_RS05895	COG3292	Two component regulator propeller
FKZ68_RS05895	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS05955	COG0582	viral genome integration into host DNA
FKZ68_RS06000	COG0702	epimerase
FKZ68_RS06005	COG1629	transport
FKZ68_RS06015	COG1629	transport
FKZ68_RS06035	COG0738	Major facilitator superfamily
FKZ68_RS06050	COG1940	carbohydrate kinase activity
FKZ68_RS06055	COG3250	beta-galactosidase activity
FKZ68_RS06065	COG1609	Transcriptional regulator
FKZ68_RS06075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKZ68_RS06080	COG1538	Outer membrane efflux protein
FKZ68_RS06090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKZ68_RS06095	COG3250	beta-galactosidase activity
FKZ68_RS06100	COG4771	TonB-dependent receptor
FKZ68_RS06110	COG1629	transport
FKZ68_RS06115	COG0702	epimerase
FKZ68_RS06165	COG1629	transport
FKZ68_RS06170	COG0702	epimerase
FKZ68_RS06175	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS06180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FKZ68_RS06190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS06195	COG3119	arylsulfatase activity
FKZ68_RS06200	COG5492	domain, Protein
FKZ68_RS06210	COG0215	cysteine-tRNA ligase activity
FKZ68_RS06215	COG0561	phosphatase activity
FKZ68_RS06230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKZ68_RS06235	COG0482	sulfurtransferase activity
FKZ68_RS06250	COG0205	6-phosphofructokinase activity
FKZ68_RS06255	COG0571	ribonuclease III activity
FKZ68_RS06260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKZ68_RS06265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKZ68_RS06275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKZ68_RS06310	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS06315	COG3475	LICD family
FKZ68_RS06320	COG4750	Nucleotidyl transferase
FKZ68_RS06340	COG1216	Glycosyl transferase, family 2
FKZ68_RS06340	COG1442	glycosyl transferase family 8
FKZ68_RS06360	COG1216	Glycosyl transferase, family 2
FKZ68_RS06365	COG1442	glycosyl transferase family 8
FKZ68_RS06365	COG1216	Glycosyl transferase, family 2
FKZ68_RS06435	COG1132	(ABC) transporter
FKZ68_RS06445	COG0463	Glycosyl transferase, family 2
FKZ68_RS06455	COG1368	sulfuric ester hydrolase activity
FKZ68_RS06465	COG3341	Caulimovirus viroplasmin
FKZ68_RS06465	COG0328	RNA-DNA hybrid ribonuclease activity
FKZ68_RS06475	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FKZ68_RS06485	COG0326	Molecular chaperone. Has ATPase activity
FKZ68_RS06495	COG1166	arginine decarboxylase activity
FKZ68_RS06500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKZ68_RS06505	COG1595	DNA-templated transcription, initiation
FKZ68_RS06550	COG0779	Required for maturation of 30S ribosomal subunits
FKZ68_RS06555	COG0195	Participates in both transcription termination and antitermination
FKZ68_RS06560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FKZ68_RS06570	COG0719	Fe-S assembly protein
FKZ68_RS06575	COG0396	ATPase activity
FKZ68_RS06580	COG0719	Fe-S assembly protein
FKZ68_RS06585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FKZ68_RS06590	COG0393	Putative heavy-metal-binding
FKZ68_RS06610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FKZ68_RS06625	COG4771	TonB-dependent receptor
FKZ68_RS06640	COG4771	TonB-dependent receptor
FKZ68_RS06645	COG0702	epimerase
FKZ68_RS06655	COG5434	Belongs to the glycosyl hydrolase 28 family
FKZ68_RS06660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FKZ68_RS06680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FKZ68_RS06695	COG0187	DNA topoisomerase II activity
FKZ68_RS06700	COG0268	Binds directly to 16S ribosomal RNA
FKZ68_RS06710	COG1381	Involved in DNA repair and RecF pathway recombination
FKZ68_RS06745	COG1610	YqeY-like protein
FKZ68_RS06750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FKZ68_RS06765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKZ68_RS06770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FKZ68_RS06775	COG0772	Belongs to the SEDS family
FKZ68_RS06780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FKZ68_RS06785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKZ68_RS06790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKZ68_RS06805	COG0275	rRNA processing
FKZ68_RS06810	COG2001	Belongs to the MraZ family
FKZ68_RS06815	COG1595	DNA-templated transcription, initiation
FKZ68_RS06830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FKZ68_RS06835	COG0756	dUTP diphosphatase activity
FKZ68_RS06850	COG4942	peptidase
FKZ68_RS06855	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS06855	COG2205	protein histidine kinase activity
FKZ68_RS06855	COG3292	Two component regulator propeller
FKZ68_RS06890	COG4771	TonB-dependent receptor
FKZ68_RS06895	COG0561	phosphatase activity
FKZ68_RS06925	COG3537	Alpha-1,2-mannosidase
FKZ68_RS06975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKZ68_RS06980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKZ68_RS06985	COG1022	Amp-dependent synthetase and ligase
FKZ68_RS07005	COG2954	triphosphatase activity
FKZ68_RS07045	COG1864	DNA RNA non-specific endonuclease
FKZ68_RS07045	COG3591	Belongs to the peptidase S1B family
FKZ68_RS07080	COG0561	phosphatase activity
FKZ68_RS07085	COG4771	TonB-dependent receptor
FKZ68_RS07115	COG2271	Major facilitator Superfamily
FKZ68_RS07125	COG1629	transport
FKZ68_RS07160	COG1595	DNA-templated transcription, initiation
FKZ68_RS07165	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS07175	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS07200	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FKZ68_RS07245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS07260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FKZ68_RS07260	COG0517	IMP dehydrogenase activity
FKZ68_RS07275	COG4771	TonB-dependent receptor
FKZ68_RS07285	COG2814	Major facilitator Superfamily
FKZ68_RS07295	COG3458	cephalosporin-C deacetylase activity
FKZ68_RS07300	COG2207	Transcriptional regulator
FKZ68_RS07300	COG1609	Transcriptional regulator
FKZ68_RS07310	COG0423	glycine-tRNA ligase activity
FKZ68_RS07335	COG0738	Major facilitator superfamily
FKZ68_RS07340	COG1063	alcohol dehydrogenase
FKZ68_RS07350	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS07360	COG1501	Belongs to the glycosyl hydrolase 31 family
FKZ68_RS07370	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS07375	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS07380	COG4771	TonB-dependent receptor
FKZ68_RS07390	COG4771	TonB-dependent receptor
FKZ68_RS07410	COG5520	Belongs to the glycosyl hydrolase 30 family
FKZ68_RS07420	COG2382	esterase
FKZ68_RS07425	COG3507	Belongs to the glycosyl hydrolase 43 family
FKZ68_RS07430	COG3292	Two component regulator propeller
FKZ68_RS07430	COG2205	protein histidine kinase activity
FKZ68_RS07430	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS07445	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FKZ68_RS07460	COG2211	Major facilitator Superfamily
FKZ68_RS07475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKZ68_RS07530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKZ68_RS07535	COG0475	glutathione-regulated potassium exporter activity
FKZ68_RS07535	COG0589	response to stress
FKZ68_RS07540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FKZ68_RS07545	COG1136	(ABC) transporter
FKZ68_RS07555	COG0733	neurotransmitter:sodium symporter activity
FKZ68_RS07570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FKZ68_RS07575	COG0784	Response regulator, receiver
FKZ68_RS07575	COG5002	protein histidine kinase activity
FKZ68_RS07580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FKZ68_RS07585	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FKZ68_RS07605	COG1082	Xylose isomerase domain protein TIM barrel
FKZ68_RS07640	COG1346	cytolysis
FKZ68_RS07645	COG1380	Effector of murein hydrolase LrgA
FKZ68_RS07650	COG0280	phosphate acetyltransferase
FKZ68_RS07655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FKZ68_RS07670	COG1216	Glycosyl transferase, family 2
FKZ68_RS07670	COG0463	Glycosyl transferase, family 2
FKZ68_RS07675	COG2003	Belongs to the UPF0758 family
FKZ68_RS07705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKZ68_RS07710	COG1629	transport
FKZ68_RS07710	COG4206	TonB-dependent receptor
FKZ68_RS07715	COG1082	Xylose isomerase domain protein TIM barrel
FKZ68_RS07720	COG0366	Alpha amylase catalytic
FKZ68_RS07730	COG1785	Belongs to the alkaline phosphatase family
FKZ68_RS07735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKZ68_RS07740	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FKZ68_RS07750	COG0515	serine threonine protein kinase
FKZ68_RS07750	COG2815	serine threonine protein kinase
FKZ68_RS07755	COG0564	pseudouridine synthase activity
FKZ68_RS07780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKZ68_RS07785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FKZ68_RS07790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FKZ68_RS07795	COG0436	Aminotransferase
FKZ68_RS07805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FKZ68_RS07820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKZ68_RS07825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKZ68_RS07835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKZ68_RS07835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKZ68_RS07840	COG2890	protein-(glutamine-N5) methyltransferase activity
FKZ68_RS07850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKZ68_RS07860	COG0165	Argininosuccinate lyase
FKZ68_RS07885	COG4206	TonB-dependent receptor
FKZ68_RS07885	COG1629	transport
FKZ68_RS07940	COG1629	transport
FKZ68_RS07955	COG4677	pectinesterase activity
FKZ68_RS07960	COG3292	Two component regulator propeller
FKZ68_RS07960	COG2205	protein histidine kinase activity
FKZ68_RS07960	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS07970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKZ68_RS07975	COG1917	Cupin 2, conserved barrel domain protein
FKZ68_RS07975	COG1396	sequence-specific DNA binding
FKZ68_RS07985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKZ68_RS07995	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FKZ68_RS08000	COG0137	argininosuccinate synthase activity
FKZ68_RS08010	COG1438	arginine binding
FKZ68_RS08020	COG1070	Carbohydrate kinase
FKZ68_RS08025	COG4806	L-rhamnose isomerase
FKZ68_RS08035	COG0235	Class ii aldolase
FKZ68_RS08040	COG1454	alcohol dehydrogenase
FKZ68_RS08050	COG3292	Two component regulator propeller
FKZ68_RS08050	COG2205	protein histidine kinase activity
FKZ68_RS08050	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS08055	COG4771	TonB-dependent receptor
FKZ68_RS08060	COG0702	epimerase
FKZ68_RS08090	COG1501	Belongs to the glycosyl hydrolase 31 family
FKZ68_RS08095	COG3250	beta-galactosidase activity
FKZ68_RS08125	COG4206	TonB-dependent receptor
FKZ68_RS08125	COG1629	transport
FKZ68_RS08130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKZ68_RS08160	COG3537	Alpha-1,2-mannosidase
FKZ68_RS08180	COG0564	pseudouridine synthase activity
FKZ68_RS08215	COG3537	Alpha-1,2-mannosidase
FKZ68_RS08220	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS08220	COG2205	protein histidine kinase activity
FKZ68_RS08220	COG3292	Two component regulator propeller
FKZ68_RS08240	COG4771	TonB-dependent receptor
FKZ68_RS08260	COG3119	arylsulfatase activity
FKZ68_RS08270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKZ68_RS08270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKZ68_RS08275	COG0612	Peptidase, M16
FKZ68_RS08280	COG0534	Mate efflux family protein
FKZ68_RS08285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKZ68_RS08285	COG2205	protein histidine kinase activity
FKZ68_RS08315	COG0488	(ABC) transporter
FKZ68_RS08320	COG3590	peptidase
FKZ68_RS08325	COG0138	bifunctional purine biosynthesis protein purh
FKZ68_RS08350	COG0772	Belongs to the SEDS family
FKZ68_RS08375	COG1774	PSP1 C-terminal conserved region
FKZ68_RS08380	COG0470	DNA polymerase III
FKZ68_RS08385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FKZ68_RS08390	COG2193	ferroxidase activity
FKZ68_RS08460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKZ68_RS08465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FKZ68_RS08470	COG1160	GTP binding
FKZ68_RS08480	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKZ68_RS08485	COG1127	ABC transporter
FKZ68_RS08490	COG0724	RNA recognition motif
FKZ68_RS08495	COG0544	peptidyl-prolyl cis-trans isomerase activity
FKZ68_RS08500	COG0740	serine-type endopeptidase activity
FKZ68_RS08505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKZ68_RS08510	COG0514	ATP-dependent DNA helicase (RecQ)
FKZ68_RS08515	COG0516	GMP reductase activity
FKZ68_RS08515	COG0517	IMP dehydrogenase activity
FKZ68_RS08530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKZ68_RS08545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FKZ68_RS08590	COG3022	response to hydroperoxide
FKZ68_RS08595	COG0110	maltose O-acetyltransferase activity
FKZ68_RS08615	COG1187	pseudouridine synthase activity
FKZ68_RS08620	COG0017	Asparaginyl-tRNA synthetase
FKZ68_RS08640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKZ68_RS08645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FKZ68_RS08650	COG0052	Belongs to the universal ribosomal protein uS2 family
FKZ68_RS08655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FKZ68_RS08670	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FKZ68_RS08675	COG0179	Fumarylacetoacetate (FAA) hydrolase
FKZ68_RS08680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FKZ68_RS08695	COG0482	sulfurtransferase activity
FKZ68_RS08705	COG1570	exodeoxyribonuclease VII activity
FKZ68_RS08715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKZ68_RS08725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FKZ68_RS08730	COG0489	protein tyrosine kinase activity
FKZ68_RS08735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKZ68_RS08740	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FKZ68_RS08775	COG0039	L-malate dehydrogenase activity
FKZ68_RS08790	COG4771	TonB-dependent receptor
FKZ68_RS08825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKZ68_RS08830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FKZ68_RS08835	COG0811	peptide transport
FKZ68_RS08840	COG0848	biopolymer transport protein
FKZ68_RS08855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FKZ68_RS08860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKZ68_RS08865	COG0105	UTP biosynthetic process
FKZ68_RS08870	COG0739	heme binding
FKZ68_RS08885	COG0149	triose-phosphate isomerase activity
FKZ68_RS08895	COG0302	gtp cyclohydrolase
FKZ68_RS08900	COG0358	DNA primase activity
FKZ68_RS08910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FKZ68_RS08935	COG0514	ATP-dependent DNA helicase (RecQ)
FKZ68_RS08940	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FKZ68_RS08940	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FKZ68_RS08955	COG4771	TonB-dependent receptor
FKZ68_RS08960	COG0702	epimerase
FKZ68_RS08980	COG1785	Belongs to the alkaline phosphatase family
FKZ68_RS09000	COG0009	L-threonylcarbamoyladenylate synthase
FKZ68_RS09010	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKZ68_RS09015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FKZ68_RS09025	COG2333	competence protein COMEC
FKZ68_RS09025	COG0658	competence protein
FKZ68_RS09030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FKZ68_RS09040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKZ68_RS09050	COG4771	TonB-dependent receptor
FKZ68_RS09060	COG3537	Alpha-1,2-mannosidase
FKZ68_RS09065	COG3537	Alpha-1,2-mannosidase
FKZ68_RS09075	COG3537	Alpha-1,2-mannosidase
FKZ68_RS09080	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS09085	COG3279	Response regulator of the LytR AlgR family
FKZ68_RS09090	COG3275	phosphorelay sensor kinase activity
FKZ68_RS09105	COG0386	Belongs to the glutathione peroxidase family
FKZ68_RS09115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FKZ68_RS09130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FKZ68_RS09145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKZ68_RS09150	COG0742	ribosomal rna small subunit methyltransferase
FKZ68_RS09195	COG1629	transport
FKZ68_RS09195	COG4206	TonB-dependent receptor
FKZ68_RS09245	COG3537	Alpha-1,2-mannosidase
FKZ68_RS09265	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKZ68_RS09270	COG0739	heme binding
FKZ68_RS09280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKZ68_RS09285	COG0741	lytic transglycosylase activity
FKZ68_RS09285	COG1388	LysM domain
FKZ68_RS09295	COG1475	DNA binding
FKZ68_RS09300	COG1192	Involved in chromosome partitioning
FKZ68_RS09305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FKZ68_RS09310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKZ68_RS09320	COG4589	Belongs to the CDS family
FKZ68_RS09325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKZ68_RS09350	COG1196	nuclear chromosome segregation
FKZ68_RS09355	COG2239	Acts as a magnesium transporter
FKZ68_RS09360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FKZ68_RS09370	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKZ68_RS09415	COG0668	transmembrane transport
FKZ68_RS09420	COG2207	Transcriptional regulator
FKZ68_RS09420	COG0662	Cupin 2, conserved barrel domain protein
FKZ68_RS09440	COG0784	Response regulator, receiver
FKZ68_RS09440	COG2198	Histidine kinase
FKZ68_RS09440	COG5002	protein histidine kinase activity
FKZ68_RS09455	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKZ68_RS09460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FKZ68_RS09465	COG0713	ATP synthesis coupled electron transport
FKZ68_RS09480	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FKZ68_RS09485	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKZ68_RS09485	COG0649	NAD binding
FKZ68_RS09490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKZ68_RS09495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FKZ68_RS09530	COG3250	beta-galactosidase activity
FKZ68_RS09540	COG3250	beta-galactosidase activity
FKZ68_RS09555	COG4771	TonB-dependent receptor
FKZ68_RS09560	COG0702	epimerase
FKZ68_RS09565	COG4771	TonB-dependent receptor
FKZ68_RS09600	COG3537	Alpha-1,2-mannosidase
FKZ68_RS09620	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKZ68_RS09625	COG0569	domain protein
FKZ68_RS09630	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKZ68_RS09650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKZ68_RS09655	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKZ68_RS09660	COG0805	protein transport
FKZ68_RS09670	COG2271	Major facilitator Superfamily
FKZ68_RS09675	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FKZ68_RS09680	COG3775	system Galactitol-specific IIC component
FKZ68_RS09685	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS09695	COG2755	lipolytic protein G-D-S-L family
FKZ68_RS09705	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS09705	COG2205	protein histidine kinase activity
FKZ68_RS09705	COG3292	Two component regulator propeller
FKZ68_RS09715	COG0702	epimerase
FKZ68_RS09720	COG4771	TonB-dependent receptor
FKZ68_RS09740	COG3279	Response regulator of the LytR AlgR family
FKZ68_RS09765	COG1629	transport
FKZ68_RS09770	COG0702	epimerase
FKZ68_RS09785	COG4677	pectinesterase activity
FKZ68_RS09800	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS09805	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS09805	COG3292	Two component regulator propeller
FKZ68_RS09805	COG2205	protein histidine kinase activity
FKZ68_RS09810	COG1242	4 iron, 4 sulfur cluster binding
FKZ68_RS09820	COG0363	glucosamine-6-phosphate deaminase activity
FKZ68_RS09825	COG0009	L-threonylcarbamoyladenylate synthase
FKZ68_RS09835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FKZ68_RS09840	COG0561	phosphatase activity
FKZ68_RS09845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FKZ68_RS09870	COG2755	lipolytic protein G-D-S-L family
FKZ68_RS09900	COG0702	epimerase
FKZ68_RS09905	COG1629	transport
FKZ68_RS09925	COG4771	TonB-dependent receptor
FKZ68_RS09935	COG1629	transport
FKZ68_RS09945	COG3401	FG-GAP repeat protein
FKZ68_RS09955	COG2755	lipolytic protein G-D-S-L family
FKZ68_RS09965	COG3401	FG-GAP repeat protein
FKZ68_RS09975	COG3254	rhamnose metabolic process
FKZ68_RS09985	COG2205	protein histidine kinase activity
FKZ68_RS09985	COG3292	Two component regulator propeller
FKZ68_RS09985	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS09985	COG3292	Two component regulator propeller
FKZ68_RS09985	COG2205	protein histidine kinase activity
FKZ68_RS09985	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS10005	COG3250	beta-galactosidase activity
FKZ68_RS10010	COG3401	FG-GAP repeat protein
FKZ68_RS10020	COG4733	cellulase activity
FKZ68_RS10040	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS10060	COG4771	TonB-dependent receptor
FKZ68_RS10065	COG0702	epimerase
FKZ68_RS10080	COG4771	TonB-dependent receptor
FKZ68_RS10105	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS10105	COG2205	protein histidine kinase activity
FKZ68_RS10105	COG3292	Two component regulator propeller
FKZ68_RS10105	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS10105	COG3292	Two component regulator propeller
FKZ68_RS10105	COG2205	protein histidine kinase activity
FKZ68_RS10115	COG0546	phosphoglycolate phosphatase activity
FKZ68_RS10140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FKZ68_RS10150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKZ68_RS10160	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FKZ68_RS10165	COG0823	Involved in the tonB-independent uptake of proteins
FKZ68_RS10165	COG1506	peptidase
FKZ68_RS10175	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKZ68_RS10190	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FKZ68_RS10190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKZ68_RS10195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKZ68_RS10200	COG1078	dGTPase activity
FKZ68_RS10205	COG0284	orotidine-5'-phosphate decarboxylase activity
FKZ68_RS10210	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKZ68_RS10215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FKZ68_RS10220	COG1704	LemA family
FKZ68_RS10235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FKZ68_RS10240	COG2226	methyltransferase
FKZ68_RS10245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FKZ68_RS10250	COG1702	phosphate starvation-inducible protein PhoH
FKZ68_RS10280	COG2268	Band 7 protein
FKZ68_RS10290	COG0101	tRNA pseudouridine synthase activity
FKZ68_RS10310	COG3250	beta-galactosidase activity
FKZ68_RS10315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKZ68_RS10320	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS10335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FKZ68_RS10345	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKZ68_RS10360	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FKZ68_RS10365	COG0793	Belongs to the peptidase S41A family
FKZ68_RS10370	COG2131	deaminase
FKZ68_RS10380	COG0339	signal peptide processing
FKZ68_RS10390	COG1970	mechanosensitive ion channel activity
FKZ68_RS10395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKZ68_RS10395	COG0519	Catalyzes the synthesis of GMP from XMP
FKZ68_RS10420	COG1629	transport
FKZ68_RS10425	COG0561	phosphatase activity
FKZ68_RS10460	COG0297	glycogen (starch) synthase activity
FKZ68_RS10475	COG0297	glycogen (starch) synthase activity
FKZ68_RS10480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FKZ68_RS10485	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FKZ68_RS10490	COG0543	2 iron, 2 sulfur cluster binding
FKZ68_RS10495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKZ68_RS10500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FKZ68_RS10505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FKZ68_RS10520	COG0791	NLP P60 protein
FKZ68_RS10535	COG0612	Peptidase, M16
FKZ68_RS10540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FKZ68_RS10545	COG1597	lipid kinase activity
FKZ68_RS10550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKZ68_RS10565	COG1136	(ABC) transporter
FKZ68_RS10585	COG2211	Major facilitator Superfamily
FKZ68_RS10595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKZ68_RS10610	COG1674	ftsk spoiiie
FKZ68_RS10620	COG0492	ferredoxin-NADP+ reductase activity
FKZ68_RS10625	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS10665	COG1629	transport
FKZ68_RS10665	COG4206	TonB-dependent receptor
FKZ68_RS10725	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKZ68_RS10725	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKZ68_RS10735	COG1234	tRNA 3'-trailer cleavage
FKZ68_RS10740	COG2989	Protein conserved in bacteria
FKZ68_RS10760	COG3956	TIGRFAM MazG family protein
FKZ68_RS10795	COG0525	valine-tRNA ligase activity
FKZ68_RS10800	COG2205	protein histidine kinase activity
FKZ68_RS10800	COG0784	Response regulator, receiver
FKZ68_RS10820	COG4771	TonB-dependent receptor
FKZ68_RS10825	COG0702	epimerase
FKZ68_RS10835	COG3119	arylsulfatase activity
FKZ68_RS10840	COG3119	arylsulfatase activity
FKZ68_RS10845	COG3408	Glycogen debranching enzyme
FKZ68_RS10850	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS10870	COG0653	protein targeting
FKZ68_RS10875	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
FKZ68_RS10885	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FKZ68_RS10905	COG1253	flavin adenine dinucleotide binding
FKZ68_RS10910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKZ68_RS10920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FKZ68_RS10930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKZ68_RS10935	COG2204	response regulator
FKZ68_RS10975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FKZ68_RS10975	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FKZ68_RS10995	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FKZ68_RS11000	COG0563	adenylate kinase activity
FKZ68_RS11005	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKZ68_RS11010	COG1496	oxidoreductase activity
FKZ68_RS11020	COG0739	heme binding
FKZ68_RS11025	COG2706	6-phosphogluconolactonase activity
FKZ68_RS11035	COG4804	nuclease activity
FKZ68_RS11060	COG1595	DNA-templated transcription, initiation
FKZ68_RS11065	COG1629	transport
FKZ68_RS11135	COG3142	Participates in the control of copper homeostasis
FKZ68_RS11140	COG1418	mRNA catabolic process
FKZ68_RS11195	COG4771	TonB-dependent receptor
FKZ68_RS11200	COG0702	epimerase
FKZ68_RS11230	COG0246	Mannitol dehydrogenase
FKZ68_RS11240	COG1063	alcohol dehydrogenase
FKZ68_RS11255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKZ68_RS11260	COG2832	Protein of unknown function (DUF454)
FKZ68_RS11270	COG0602	queuosine metabolic process
FKZ68_RS11275	COG0247	lactate metabolic process
FKZ68_RS11280	COG1139	Iron-sulfur cluster binding protein
FKZ68_RS11290	COG0351	phosphomethylpyrimidine kinase
FKZ68_RS11315	COG4589	Belongs to the CDS family
FKZ68_RS11325	COG2304	oxidoreductase activity
FKZ68_RS11340	COG1393	Belongs to the ArsC family
FKZ68_RS11350	COG4771	TonB-dependent receptor
FKZ68_RS11380	COG2233	PERMEase
FKZ68_RS11390	COG0686	Belongs to the AlaDH PNT family
FKZ68_RS11405	COG4206	TonB-dependent receptor
FKZ68_RS11405	COG1629	transport
FKZ68_RS11425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKZ68_RS11440	COG0488	(ABC) transporter
FKZ68_RS11445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKZ68_RS11450	COG3059	membrane
FKZ68_RS11460	COG0295	cytidine deaminase activity
FKZ68_RS11465	COG1705	Flagellar rod assembly protein muramidase FlgJ
FKZ68_RS11470	COG1252	NADH dehydrogenase
FKZ68_RS11480	COG1136	(ABC) transporter
FKZ68_RS11490	COG0577	efflux transmembrane transporter activity
FKZ68_RS11510	COG2204	response regulator
FKZ68_RS11515	COG4191	Histidine kinase
FKZ68_RS11530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FKZ68_RS11540	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FKZ68_RS11555	COG1979	alcohol dehydrogenase
FKZ68_RS11560	COG4771	TonB-dependent receptor
FKZ68_RS11595	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS11640	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS11650	COG0776	regulation of translation
FKZ68_RS11680	COG1285	pathogenesis
FKZ68_RS11700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKZ68_RS11705	COG0741	lytic transglycosylase activity
FKZ68_RS11705	COG1388	LysM domain
FKZ68_RS11740	COG0534	Mate efflux family protein
FKZ68_RS11750	COG0564	pseudouridine synthase activity
FKZ68_RS11785	COG0346	lactoylglutathione lyase activity
FKZ68_RS11795	COG0653	protein targeting
FKZ68_RS11840	COG0513	Belongs to the DEAD box helicase family
FKZ68_RS11880	COG1063	alcohol dehydrogenase
FKZ68_RS11925	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FKZ68_RS11930	COG4804	nuclease activity
FKZ68_RS11980	COG1910	domain protein
FKZ68_RS12005	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS12015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FKZ68_RS12020	COG2205	protein histidine kinase activity
FKZ68_RS12020	COG0784	Response regulator, receiver
FKZ68_RS12025	COG0702	epimerase
FKZ68_RS12035	COG4864	UPF0365 protein
FKZ68_RS12050	COG0037	tRNA processing
FKZ68_RS12060	COG1477	protein flavinylation
FKZ68_RS12065	COG1971	Probably functions as a manganese efflux pump
FKZ68_RS12080	COG0463	Glycosyl transferase, family 2
FKZ68_RS12110	COG0148	phosphopyruvate hydratase activity
FKZ68_RS12120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKZ68_RS12125	COG1082	Xylose isomerase domain protein TIM barrel
FKZ68_RS12130	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FKZ68_RS12135	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKZ68_RS12140	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FKZ68_RS12145	COG4651	solute:proton antiporter activity
FKZ68_RS12145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKZ68_RS12155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FKZ68_RS12160	COG0193	aminoacyl-tRNA hydrolase activity
FKZ68_RS12165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FKZ68_RS12175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKZ68_RS12190	COG0237	dephospho-CoA kinase activity
FKZ68_RS12205	COG0542	response to heat
FKZ68_RS12220	COG0583	DNA-binding transcription factor activity
FKZ68_RS12255	COG1373	ATPase (AAA superfamily
FKZ68_RS12260	COG3304	Inner membrane component domain
FKZ68_RS12265	COG2855	membrane
FKZ68_RS12270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FKZ68_RS12275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FKZ68_RS12300	COG0443	Heat shock 70 kDa protein
FKZ68_RS12365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKZ68_RS12380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKZ68_RS12380	COG4651	solute:proton antiporter activity
FKZ68_RS12385	COG0306	phosphate transporter
FKZ68_RS12395	COG0586	Pfam SNARE associated Golgi protein
FKZ68_RS12405	COG0456	acetyltransferase
FKZ68_RS12405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FKZ68_RS12455	COG0038	chloride channel
FKZ68_RS12460	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FKZ68_RS12475	COG1940	carbohydrate kinase activity
FKZ68_RS12485	COG3119	arylsulfatase activity
FKZ68_RS12495	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS12500	COG0702	epimerase
FKZ68_RS12505	COG4771	TonB-dependent receptor
FKZ68_RS12515	COG5434	Belongs to the glycosyl hydrolase 28 family
FKZ68_RS12525	COG3292	Two component regulator propeller
FKZ68_RS12525	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS12525	COG2205	protein histidine kinase activity
FKZ68_RS12530	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FKZ68_RS12535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKZ68_RS12545	COG3250	beta-galactosidase activity
FKZ68_RS12560	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS12585	COG0562	UDP-galactopyranose mutase
FKZ68_RS12600	COG1454	alcohol dehydrogenase
FKZ68_RS12605	COG3475	LICD family
FKZ68_RS12615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FKZ68_RS12615	COG1215	transferase activity, transferring glycosyl groups
FKZ68_RS12620	COG1216	Glycosyl transferase, family 2
FKZ68_RS12650	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS12680	COG1760	l-serine dehydratase
FKZ68_RS12685	COG0598	Magnesium transport protein CorA
FKZ68_RS12690	COG1193	negative regulation of DNA recombination
FKZ68_RS12705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKZ68_RS12720	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FKZ68_RS12725	COG0456	acetyltransferase
FKZ68_RS12735	COG3189	MarR family transcriptional regulator
FKZ68_RS12740	COG0561	phosphatase activity
FKZ68_RS12745	COG1169	isochorismate synthase
FKZ68_RS12750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FKZ68_RS12755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FKZ68_RS12760	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS12770	COG1191	sigma factor activity
FKZ68_RS12780	COG4771	TonB-dependent receptor
FKZ68_RS12810	COG0783	Belongs to the Dps family
FKZ68_RS12815	COG0583	DNA-binding transcription factor activity
FKZ68_RS12820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKZ68_RS12840	COG1595	DNA-templated transcription, initiation
FKZ68_RS12855	COG4771	TonB-dependent receptor
FKZ68_RS12865	COG0584	glycerophosphoryl diester phosphodiesterase
FKZ68_RS12870	COG0584	glycerophosphoryl diester phosphodiesterase
FKZ68_RS12895	COG4771	TonB-dependent receptor
FKZ68_RS12900	COG0702	epimerase
FKZ68_RS12910	COG0584	glycerophosphoryl diester phosphodiesterase
FKZ68_RS12915	COG2271	Major facilitator Superfamily
FKZ68_RS12935	COG4680	protein conserved in bacteria
FKZ68_RS12965	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS12970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FKZ68_RS12975	COG1882	Formate acetyltransferase
FKZ68_RS13045	COG3292	Two component regulator propeller
FKZ68_RS13045	COG2205	protein histidine kinase activity
FKZ68_RS13045	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS13060	COG1629	transport
FKZ68_RS13065	COG0561	phosphatase activity
FKZ68_RS13100	COG1028	Short-chain dehydrogenase reductase Sdr
FKZ68_RS13110	COG3547	Transposase (IS116 IS110 IS902 family)
FKZ68_RS13120	COG1082	Xylose isomerase domain protein TIM barrel
FKZ68_RS13145	COG2267	carboxylic ester hydrolase activity
FKZ68_RS13165	COG1629	transport
FKZ68_RS13165	COG4206	TonB-dependent receptor
FKZ68_RS13175	COG5492	domain, Protein
FKZ68_RS13185	COG3250	beta-galactosidase activity
FKZ68_RS13200	COG1629	transport
FKZ68_RS13205	COG0702	epimerase
FKZ68_RS13225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS13235	COG1253	flavin adenine dinucleotide binding
FKZ68_RS13250	COG0501	Belongs to the peptidase M48B family
FKZ68_RS13275	COG0793	Belongs to the peptidase S41A family
FKZ68_RS13280	COG0482	sulfurtransferase activity
FKZ68_RS13295	COG2197	response regulator
FKZ68_RS13305	COG1757	Na H antiporter
FKZ68_RS13315	COG2814	Major facilitator Superfamily
FKZ68_RS13320	COG4953	penicillin-binding protein 1C
FKZ68_RS13325	COG2373	Large extracellular alpha-helical protein
FKZ68_RS13330	COG0545	Peptidyl-prolyl cis-trans isomerase
FKZ68_RS13370	COG0768	penicillin binding
FKZ68_RS13390	COG2003	Belongs to the UPF0758 family
FKZ68_RS13515	COG0358	DNA primase activity
FKZ68_RS13665	COG2205	protein histidine kinase activity
FKZ68_RS13665	COG0784	Response regulator, receiver
FKZ68_RS13665	COG2198	Histidine kinase
FKZ68_RS13665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKZ68_RS13685	COG0551	DNA topoisomerase type I activity
FKZ68_RS13685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKZ68_RS13725	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS13745	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FKZ68_RS13750	COG0646	methionine synthase
FKZ68_RS13750	COG1410	methionine synthase
FKZ68_RS13755	COG0778	Nitroreductase
FKZ68_RS13760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKZ68_RS13770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FKZ68_RS13775	COG0572	uridine kinase
FKZ68_RS13785	COG4232	protein-disulfide reductase activity
FKZ68_RS13800	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS13810	COG3250	beta-galactosidase activity
FKZ68_RS13825	COG4771	TonB-dependent receptor
FKZ68_RS13855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FKZ68_RS13860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FKZ68_RS13865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FKZ68_RS13870	COG0131	Imidazoleglycerol-phosphate dehydratase
FKZ68_RS13880	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FKZ68_RS13880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKZ68_RS13905	COG3385	transposase activity
FKZ68_RS13950	COG1773	rubredoxin
FKZ68_RS13950	COG1592	Rubrerythrin
FKZ68_RS13965	COG3118	belongs to the thioredoxin family
FKZ68_RS13970	COG3591	Belongs to the peptidase S1B family
FKZ68_RS13975	COG3591	Belongs to the peptidase S1B family
FKZ68_RS13980	COG0641	radical SAM
FKZ68_RS14005	COG0420	3'-5' exonuclease activity
FKZ68_RS14025	COG1410	methionine synthase
FKZ68_RS14025	COG0646	methionine synthase
FKZ68_RS14030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FKZ68_RS14035	COG0463	Glycosyl transferase, family 2
FKZ68_RS14040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKZ68_RS14055	COG1032	radical SAM domain protein
FKZ68_RS14075	COG0363	glucosamine-6-phosphate deaminase activity
FKZ68_RS14080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKZ68_RS14105	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS14125	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKZ68_RS14165	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKZ68_RS14170	COG0022	dehydrogenase e1 component
FKZ68_RS14180	COG2264	protein methyltransferase activity
FKZ68_RS14205	COG0590	tRNA wobble adenosine to inosine editing
FKZ68_RS14210	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS14220	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FKZ68_RS14385	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS14390	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS14470	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS14495	COG1501	Belongs to the glycosyl hydrolase 31 family
FKZ68_RS14500	COG5012	cobalamin binding
FKZ68_RS14515	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FKZ68_RS14520	COG0698	ribose 5-phosphate isomerase
FKZ68_RS14525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FKZ68_RS14540	COG1070	Carbohydrate kinase
FKZ68_RS14545	COG2160	L-arabinose isomerase activity
FKZ68_RS14555	COG2816	NAD+ diphosphatase activity
FKZ68_RS14585	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FKZ68_RS14600	COG1482	cell wall glycoprotein biosynthetic process
FKZ68_RS14620	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS14685	COG3385	transposase activity
FKZ68_RS14715	COG1216	Glycosyl transferase, family 2
FKZ68_RS14715	COG1442	glycosyl transferase family 8
FKZ68_RS14725	COG0562	UDP-galactopyranose mutase
FKZ68_RS14730	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS14745	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS14750	COG0110	maltose O-acetyltransferase activity
FKZ68_RS14755	COG0297	glycogen (starch) synthase activity
FKZ68_RS14760	COG0110	maltose O-acetyltransferase activity
FKZ68_RS14805	COG4221	oxidoreductase activity
FKZ68_RS14815	COG1218	3'(2'),5'-bisphosphate nucleotidase
FKZ68_RS14820	COG3273	potassium ion transport
FKZ68_RS14820	COG0471	metal ion transport
FKZ68_RS14825	COG0529	Catalyzes the synthesis of activated sulfate
FKZ68_RS14830	COG0175	sulfate reduction
FKZ68_RS14835	COG2895	sulfate adenylyltransferase (ATP) activity
FKZ68_RS14860	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKZ68_RS14865	COG0242	peptide deformylase activity
FKZ68_RS14875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKZ68_RS14880	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FKZ68_RS14885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FKZ68_RS14890	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FKZ68_RS14900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKZ68_RS14905	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FKZ68_RS14910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKZ68_RS14910	COG0674	pyruvate-flavodoxin oxidoreductase activity
FKZ68_RS14910	COG1013	pyruvate-flavodoxin oxidoreductase activity
FKZ68_RS14910	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FKZ68_RS14920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FKZ68_RS14930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKZ68_RS14945	COG1940	carbohydrate kinase activity
FKZ68_RS14960	COG2814	Major facilitator Superfamily
FKZ68_RS15030	COG1082	Xylose isomerase domain protein TIM barrel
FKZ68_RS15045	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS15080	COG4771	TonB-dependent receptor
FKZ68_RS15105	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS15110	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS15115	COG4771	TonB-dependent receptor
FKZ68_RS15120	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKZ68_RS15125	COG4335	DNA alkylation repair
FKZ68_RS15130	COG0484	heat shock protein binding
FKZ68_RS15135	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKZ68_RS15140	COG0488	(ABC) transporter
FKZ68_RS15175	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS15195	COG2183	response to ionizing radiation
FKZ68_RS15200	COG2202	Pas domain
FKZ68_RS15200	COG2205	protein histidine kinase activity
FKZ68_RS15205	COG0737	Belongs to the 5'-nucleotidase family
FKZ68_RS15235	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FKZ68_RS15250	COG2985	domain, Protein
FKZ68_RS15250	COG0490	domain, Protein
FKZ68_RS15255	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FKZ68_RS15265	COG1022	Amp-dependent synthetase and ligase
FKZ68_RS15275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKZ68_RS15280	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FKZ68_RS15285	COG1301	dicarboxylic acid transport
FKZ68_RS15290	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FKZ68_RS15295	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKZ68_RS15300	COG0363	glucosamine-6-phosphate deaminase activity
FKZ68_RS15305	COG2837	iron assimilation
FKZ68_RS15315	COG3279	Response regulator of the LytR AlgR family
FKZ68_RS15325	COG0577	efflux transmembrane transporter activity
FKZ68_RS15325	COG1136	(ABC) transporter
FKZ68_RS15330	COG1136	(ABC) transporter
FKZ68_RS15350	COG1271	oxidase subunit
FKZ68_RS15360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKZ68_RS15365	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FKZ68_RS15395	COG0501	Belongs to the peptidase M48B family
FKZ68_RS15400	COG1704	LemA family
FKZ68_RS15410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKZ68_RS15415	COG2885	chlorophyll binding
FKZ68_RS15420	COG0534	Mate efflux family protein
FKZ68_RS15425	COG2755	lipolytic protein G-D-S-L family
FKZ68_RS15425	COG0657	acetylesterase activity
FKZ68_RS15430	COG2205	protein histidine kinase activity
FKZ68_RS15430	COG0784	Response regulator, receiver
FKZ68_RS15440	COG0488	(ABC) transporter
FKZ68_RS15445	COG1629	transport
FKZ68_RS15445	COG4206	TonB-dependent receptor
FKZ68_RS15455	COG2205	protein histidine kinase activity
FKZ68_RS15455	COG0784	Response regulator, receiver
FKZ68_RS15485	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS15495	COG2244	polysaccharide biosynthetic process
FKZ68_RS15555	COG1805	sodium ion transport
FKZ68_RS15560	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FKZ68_RS15575	COG2871	sodium ion transport
FKZ68_RS15590	COG0513	Belongs to the DEAD box helicase family
FKZ68_RS15600	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKZ68_RS15615	COG1739	Uncharacterized protein family UPF0029
FKZ68_RS15630	COG0778	Nitroreductase
FKZ68_RS15635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKZ68_RS15635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKZ68_RS15640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKZ68_RS15645	COG0357	Ribosomal RNA small subunit methyltransferase G
FKZ68_RS15660	COG1408	metallophosphoesterase
FKZ68_RS15680	COG2217	Heavy metal translocating P-type atpase
FKZ68_RS15705	COG0321	lipoyl(octanoyl) transferase activity
FKZ68_RS15715	COG2755	lipolytic protein G-D-S-L family
FKZ68_RS15715	COG0657	acetylesterase activity
FKZ68_RS15735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FKZ68_RS15745	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FKZ68_RS15760	COG1678	Uncharacterized ACR, COG1678
FKZ68_RS15775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKZ68_RS15785	COG0305	Participates in initiation and elongation during chromosome replication
FKZ68_RS15810	COG3969	phosphoadenosine phosphosulfate
FKZ68_RS15815	COG1475	DNA binding
FKZ68_RS15880	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS15955	COG1629	transport
FKZ68_RS15955	COG4206	TonB-dependent receptor
FKZ68_RS15990	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FKZ68_RS15995	COG3537	Alpha-1,2-mannosidase
FKZ68_RS16010	COG1629	transport
FKZ68_RS16010	COG4206	TonB-dependent receptor
FKZ68_RS16015	COG0702	epimerase
FKZ68_RS16050	COG3408	Glycogen debranching enzyme
FKZ68_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
FKZ68_RS16090	COG3408	Glycogen debranching enzyme
FKZ68_RS16100	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS16120	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS16160	COG1629	transport
FKZ68_RS16160	COG4206	TonB-dependent receptor
FKZ68_RS16210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKZ68_RS16220	COG4232	protein-disulfide reductase activity
FKZ68_RS16235	COG3420	alginic acid biosynthetic process
FKZ68_RS16255	COG1629	transport
FKZ68_RS16255	COG4206	TonB-dependent receptor
FKZ68_RS16295	COG0582	viral genome integration into host DNA
FKZ68_RS16330	COG3250	beta-galactosidase activity
FKZ68_RS16340	COG2205	protein histidine kinase activity
FKZ68_RS16340	COG0784	Response regulator, receiver
FKZ68_RS16345	COG3250	beta-galactosidase activity
FKZ68_RS16350	COG3250	beta-galactosidase activity
FKZ68_RS16355	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS16360	COG5002	protein histidine kinase activity
FKZ68_RS16405	COG3385	transposase activity
FKZ68_RS16460	COG3547	Transposase (IS116 IS110 IS902 family)
FKZ68_RS16475	COG3250	beta-galactosidase activity
FKZ68_RS16480	COG3292	Two component regulator propeller
FKZ68_RS16480	COG2205	protein histidine kinase activity
FKZ68_RS16480	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS16510	COG2966	Psort location CytoplasmicMembrane, score
FKZ68_RS16525	COG0300	oxidoreductase activity
FKZ68_RS16530	COG1011	Hydrolase
FKZ68_RS16560	COG1733	regulation of RNA biosynthetic process
FKZ68_RS16600	COG4206	TonB-dependent receptor
FKZ68_RS16645	COG0442	prolyl-tRNA aminoacylation
FKZ68_RS16655	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS16660	COG2205	protein histidine kinase activity
FKZ68_RS16695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKZ68_RS16705	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FKZ68_RS16710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FKZ68_RS16720	COG0552	protein localization to endoplasmic reticulum
FKZ68_RS16725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKZ68_RS16740	COG0714	Associated with various cellular activities
FKZ68_RS16755	COG2304	oxidoreductase activity
FKZ68_RS16835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKZ68_RS16845	COG0326	Molecular chaperone. Has ATPase activity
FKZ68_RS16850	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKZ68_RS16895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKZ68_RS16900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKZ68_RS16905	COG0336	Belongs to the RNA methyltransferase TrmD family
FKZ68_RS16910	COG0167	dihydroorotate dehydrogenase activity
FKZ68_RS16915	COG0543	2 iron, 2 sulfur cluster binding
FKZ68_RS16930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKZ68_RS16945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKZ68_RS16950	COG1538	Outer membrane efflux protein
FKZ68_RS16960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FKZ68_RS16965	COG1595	DNA-templated transcription, initiation
FKZ68_RS16985	COG4988	ABC transporter
FKZ68_RS17010	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FKZ68_RS17015	COG1597	lipid kinase activity
FKZ68_RS17020	COG0156	8-amino-7-oxononanoate synthase activity
FKZ68_RS17030	COG1136	(ABC) transporter
FKZ68_RS17030	COG0577	efflux transmembrane transporter activity
FKZ68_RS17035	COG1136	(ABC) transporter
FKZ68_RS17070	COG3852	Histidine kinase
FKZ68_RS17080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKZ68_RS17110	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FKZ68_RS17115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FKZ68_RS17140	COG3830	Belongs to the UPF0237 family
FKZ68_RS17140	COG0560	Phosphoserine phosphatase
FKZ68_RS17145	COG0513	Belongs to the DEAD box helicase family
FKZ68_RS17175	COG0246	Mannitol dehydrogenase
FKZ68_RS17180	COG1609	Transcriptional regulator
FKZ68_RS17185	COG1904	glucuronate isomerase
FKZ68_RS17520	COG0484	heat shock protein binding
FKZ68_RS17565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKZ68_RS17570	COG0756	dUTP diphosphatase activity
FKZ68_RS17755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKZ68_RS17755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKZ68_RS17810	COG0587	DNA-directed DNA polymerase activity
FKZ68_RS17820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FKZ68_RS17825	COG0587	DNA-directed DNA polymerase activity
FKZ68_RS17910	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS17925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FKZ68_RS17965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKZ68_RS17980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKZ68_RS17990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKZ68_RS18000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKZ68_RS18000	COG3153	acetyltransferase
FKZ68_RS18015	COG2814	Major facilitator Superfamily
FKZ68_RS18015	COG0477	Major facilitator Superfamily
FKZ68_RS18020	COG2115	Belongs to the xylose isomerase family
FKZ68_RS18035	COG0351	phosphomethylpyrimidine kinase
FKZ68_RS18040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FKZ68_RS18050	COG0045	succinate-CoA ligase (ADP-forming) activity
FKZ68_RS18055	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FKZ68_RS18095	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
FKZ68_RS18100	COG0348	domain, Protein
FKZ68_RS18120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FKZ68_RS18135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKZ68_RS18315	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FKZ68_RS18405	COG2205	protein histidine kinase activity
FKZ68_RS18410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKZ68_RS18425	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FKZ68_RS18435	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FKZ68_RS18490	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FKZ68_RS18505	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FKZ68_RS18535	COG0110	maltose O-acetyltransferase activity
FKZ68_RS18585	COG0540	Belongs to the ATCase OTCase family
FKZ68_RS18590	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FKZ68_RS18605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FKZ68_RS18610	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FKZ68_RS18615	COG2985	domain, Protein
FKZ68_RS18655	COG1917	Cupin 2, conserved barrel domain protein
FKZ68_RS18655	COG2207	Transcriptional regulator
FKZ68_RS18660	COG2207	Transcriptional regulator
FKZ68_RS18675	COG1690	Belongs to the RtcB family
FKZ68_RS18680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKZ68_RS18680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKZ68_RS18690	COG2431	L-lysine efflux transmembrane transporter activity
FKZ68_RS18695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FKZ68_RS18705	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FKZ68_RS18710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FKZ68_RS18715	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKZ68_RS18720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FKZ68_RS18725	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKZ68_RS18730	COG0356	it plays a direct role in the translocation of protons across the membrane
FKZ68_RS18740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKZ68_RS18745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKZ68_RS18750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FKZ68_RS18755	COG0454	-acetyltransferase
FKZ68_RS18785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKZ68_RS18795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FKZ68_RS18805	COG0534	Mate efflux family protein
FKZ68_RS18815	COG1136	(ABC) transporter
FKZ68_RS18815	COG0577	efflux transmembrane transporter activity
FKZ68_RS18830	COG2204	response regulator
FKZ68_RS18845	COG1151	hydroxylamine reductase activity
FKZ68_RS18850	COG2233	PERMEase
FKZ68_RS18860	COG1022	Amp-dependent synthetase and ligase
FKZ68_RS18865	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS18870	COG5002	protein histidine kinase activity
FKZ68_RS18890	COG3118	belongs to the thioredoxin family
FKZ68_RS18970	COG0681	Belongs to the peptidase S26 family
FKZ68_RS19045	COG5002	protein histidine kinase activity
FKZ68_RS19055	COG0352	thiamine-phosphate diphosphorylase activity
FKZ68_RS19060	COG2022	thiamine diphosphate biosynthetic process
FKZ68_RS19065	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FKZ68_RS19075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKZ68_RS19080	COG0352	thiamine-phosphate diphosphorylase activity
FKZ68_RS19105	COG0574	Belongs to the PEP-utilizing enzyme family
FKZ68_RS19105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKZ68_RS19115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKZ68_RS19120	COG0564	pseudouridine synthase activity
FKZ68_RS19145	COG0024	Methionine aminopeptidase
FKZ68_RS19155	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FKZ68_RS19165	COG0481	GTPase activity
FKZ68_RS19190	COG0708	Exodeoxyribonuclease III
FKZ68_RS19205	COG0217	transcriptional regulatory protein
FKZ68_RS19210	COG0072	phenylalanine-tRNA ligase activity
FKZ68_RS19210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKZ68_RS19215	COG0305	Participates in initiation and elongation during chromosome replication
FKZ68_RS19220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FKZ68_RS19225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKZ68_RS19230	COG4657	Part of a membrane complex involved in electron transport
FKZ68_RS19235	COG4660	Part of a membrane complex involved in electron transport
FKZ68_RS19240	COG4659	FMN binding
FKZ68_RS19245	COG4658	electron transport chain
FKZ68_RS19250	COG4656	Part of a membrane complex involved in electron transport
FKZ68_RS19305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKZ68_RS19330	COG0438	transferase activity, transferring glycosyl groups
FKZ68_RS19360	COG1216	Glycosyl transferase, family 2
FKZ68_RS19395	COG1086	Polysaccharide biosynthesis protein
FKZ68_RS19430	COG0504	CTP synthase activity
FKZ68_RS19435	COG0706	membrane insertase activity
FKZ68_RS19440	COG0534	Mate efflux family protein
FKZ68_RS19445	COG1506	peptidase
FKZ68_RS19445	COG0823	Involved in the tonB-independent uptake of proteins
FKZ68_RS19465	COG1983	PspC domain protein
FKZ68_RS19485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FKZ68_RS19495	COG1388	LysM domain
FKZ68_RS19495	COG3942	CHAP domain
FKZ68_RS19525	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FKZ68_RS19530	COG0556	nucleotide-excision repair
FKZ68_RS19545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKZ68_RS19555	COG0842	Transport permease protein
FKZ68_RS19560	COG0842	Transport permease protein
FKZ68_RS19565	COG1131	(ABC) transporter
FKZ68_RS19570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKZ68_RS19595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKZ68_RS19600	COG0505	Belongs to the CarA family
FKZ68_RS19610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKZ68_RS19615	COG0067	glutamate synthase
FKZ68_RS19615	COG0069	glutamate synthase activity
FKZ68_RS19615	COG0070	glutamate synthase
FKZ68_RS19625	COG0367	asparagine synthase
FKZ68_RS19640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FKZ68_RS19645	COG0436	Aminotransferase
FKZ68_RS19655	COG0347	Belongs to the P(II) protein family
FKZ68_RS19660	COG0004	ammonium transporteR
FKZ68_RS19690	COG0490	domain, Protein
FKZ68_RS19690	COG0471	metal ion transport
FKZ68_RS19695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKZ68_RS19695	COG2205	protein histidine kinase activity
FKZ68_RS19700	COG1979	alcohol dehydrogenase
FKZ68_RS19710	COG0133	tryptophan synthase activity
FKZ68_RS19715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FKZ68_RS19725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FKZ68_RS19730	COG0134	indole-3-glycerol-phosphate synthase activity
FKZ68_RS19735	COG0135	phosphoribosylanthranilate isomerase activity
FKZ68_RS19740	COG0159	tryptophan synthase activity
FKZ68_RS19745	COG0252	asparaginase activity
FKZ68_RS19755	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS19760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FKZ68_RS19775	COG2197	response regulator
FKZ68_RS19785	COG0138	bifunctional purine biosynthesis protein purh
FKZ68_RS19805	COG1730	sister chromatid segregation
FKZ68_RS19835	COG1333	cytochrome c biogenesis protein
FKZ68_RS19835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKZ68_RS19845	COG1132	(ABC) transporter
FKZ68_RS19850	COG1132	(ABC) transporter
FKZ68_RS19850	COG2375	cellular response to nickel ion
FKZ68_RS19855	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS19890	COG4771	TonB-dependent receptor
FKZ68_RS19900	COG4771	TonB-dependent receptor
FKZ68_RS19910	COG0490	domain, Protein
FKZ68_RS19910	COG2985	domain, Protein
FKZ68_RS19930	COG1609	Transcriptional regulator
FKZ68_RS19935	COG2721	sulfolactate sulfo-lyase activity
FKZ68_RS19950	COG4452	Inner membrane protein CreD
FKZ68_RS19980	COG1733	regulation of RNA biosynthetic process
FKZ68_RS20015	COG0551	DNA topoisomerase type I activity
FKZ68_RS20015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKZ68_RS20060	COG0739	heme binding
FKZ68_RS20235	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS20260	COG1192	Involved in chromosome partitioning
FKZ68_RS20400	COG0228	four-way junction DNA binding
FKZ68_RS20410	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FKZ68_RS20420	COG1070	Carbohydrate kinase
FKZ68_RS20430	COG0738	Major facilitator superfamily
FKZ68_RS20445	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS20605	COG1475	DNA binding
FKZ68_RS20625	COG1192	Involved in chromosome partitioning
FKZ68_RS20630	COG0629	single-stranded DNA binding
FKZ68_RS20700	COG0542	response to heat
FKZ68_RS20855	COG3547	Transposase (IS116 IS110 IS902 family)
FKZ68_RS20890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKZ68_RS20895	COG0739	heme binding
FKZ68_RS20895	COG0741	lytic transglycosylase activity
FKZ68_RS20895	COG1196	nuclear chromosome segregation
FKZ68_RS20955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FKZ68_RS21145	COG2207	Transcriptional regulator
FKZ68_RS21150	COG2204	response regulator
FKZ68_RS21170	COG1177	transmembrane transport
FKZ68_RS21175	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKZ68_RS21180	COG3842	ATPase activity
FKZ68_RS21185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKZ68_RS21190	COG0058	SHG alpha-glucan phosphorylase activity
FKZ68_RS21200	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKZ68_RS21220	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FKZ68_RS21280	COG1472	Belongs to the glycosyl hydrolase 3 family
FKZ68_RS21285	COG0702	epimerase
FKZ68_RS21290	COG1629	transport
FKZ68_RS21300	COG1629	transport
FKZ68_RS21330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKZ68_RS21335	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKZ68_RS21340	COG4948	Mandelate Racemase Muconate Lactonizing
FKZ68_RS21355	COG1295	ribonuclease BN
FKZ68_RS21360	COG0778	Nitroreductase
FKZ68_RS21370	COG0704	Plays a role in the regulation of phosphate uptake
FKZ68_RS21375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FKZ68_RS21380	COG0581	inorganic phosphate transmembrane transporter activity
FKZ68_RS21385	COG0573	inorganic phosphate transmembrane transporter activity
FKZ68_RS21395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKZ68_RS21405	COG0586	Pfam SNARE associated Golgi protein
FKZ68_RS21415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FKZ68_RS21430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FKZ68_RS21440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FKZ68_RS21490	COG3023	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS21520	COG0110	maltose O-acetyltransferase activity
FKZ68_RS21540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FKZ68_RS21590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKZ68_RS21595	COG0497	DNA recombination
FKZ68_RS21610	COG0592	DNA-directed DNA polymerase activity
FKZ68_RS21630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FKZ68_RS21630	COG0321	lipoyl(octanoyl) transferase activity
FKZ68_RS21635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FKZ68_RS21645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKZ68_RS21650	COG0156	8-amino-7-oxononanoate synthase activity
FKZ68_RS21660	COG5002	protein histidine kinase activity
FKZ68_RS21670	COG0019	diaminopimelate decarboxylase activity
FKZ68_RS21675	COG0527	aspartate kinase activity
FKZ68_RS21680	COG2884	Cell division ATP-binding protein ftsE
FKZ68_RS21685	COG0140	phosphoribosyl-ATP diphosphatase activity
FKZ68_RS21685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FKZ68_RS21690	COG0107	imidazoleglycerol-phosphate synthase activity
FKZ68_RS21695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FKZ68_RS21700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FKZ68_RS21705	COG0788	formyltetrahydrofolate deformylase activity
FKZ68_RS21720	COG0693	protein deglycase activity
FKZ68_RS21745	COG0534	Mate efflux family protein
FKZ68_RS21755	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKZ68_RS21770	COG4884	unkown
FKZ68_RS21770	COG3831	ATPase activity
FKZ68_RS21775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKZ68_RS21775	COG2885	chlorophyll binding
FKZ68_RS21815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FKZ68_RS21830	COG2814	Major facilitator Superfamily
FKZ68_RS21845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKZ68_RS21860	COG4946	Tricorn protease homolog
FKZ68_RS21860	COG1506	peptidase
FKZ68_RS21860	COG0823	Involved in the tonB-independent uptake of proteins
FKZ68_RS21870	COG0655	NAD(P)H dehydrogenase (quinone) activity
FKZ68_RS21885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKZ68_RS21895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FKZ68_RS21910	COG4771	TonB-dependent receptor
FKZ68_RS21930	COG3385	transposase activity
FKZ68_RS22000	COG0681	Belongs to the peptidase S26 family
FKZ68_RS22025	COG4884	unkown
FKZ68_RS22025	COG3831	ATPase activity
FKZ68_RS22040	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FKZ68_RS22045	COG1162	GTPase activity
FKZ68_RS22075	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FKZ68_RS22080	COG5002	protein histidine kinase activity
FKZ68_RS22090	COG1312	Catalyzes the dehydration of D-mannonate
FKZ68_RS22095	COG1028	Short-chain dehydrogenase reductase Sdr
FKZ68_RS22100	COG1609	Transcriptional regulator
FKZ68_RS22115	COG2223	nitrite transmembrane transporter activity
FKZ68_RS22125	COG4771	TonB-dependent receptor
FKZ68_RS22135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FKZ68_RS22135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKZ68_RS22150	COG2226	methyltransferase
FKZ68_RS22185	COG2205	protein histidine kinase activity
FKZ68_RS22185	COG0784	Response regulator, receiver
FKZ68_RS22190	COG0511	ligase activity, forming carbon-carbon bonds
FKZ68_RS22195	COG0439	Biotin carboxylase
FKZ68_RS22200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKZ68_RS22210	COG1620	l-lactate permease
FKZ68_RS22215	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS22300	COG0739	heme binding
FKZ68_RS22375	COG2205	protein histidine kinase activity
FKZ68_RS22375	COG0784	Response regulator, receiver
FKZ68_RS22375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKZ68_RS22375	COG2198	Histidine kinase
FKZ68_RS22385	COG0010	Belongs to the arginase family
FKZ68_RS22390	COG0058	SHG alpha-glucan phosphorylase activity
FKZ68_RS22395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKZ68_RS22395	COG4651	solute:proton antiporter activity
FKZ68_RS22400	COG0205	6-phosphofructokinase activity
FKZ68_RS22415	COG0588	phosphoglycerate mutase activity
FKZ68_RS22420	COG1830	Aldolase
FKZ68_RS22430	COG2095	MarC family integral membrane protein
FKZ68_RS22470	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS22470	COG2205	protein histidine kinase activity
FKZ68_RS22470	COG3292	Two component regulator propeller
FKZ68_RS22475	COG1629	transport
FKZ68_RS22480	COG0702	epimerase
FKZ68_RS22530	COG3292	Two component regulator propeller
FKZ68_RS22530	COG2205	protein histidine kinase activity
FKZ68_RS22530	COG2205	protein histidine kinase activity
FKZ68_RS22530	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS22530	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS22530	COG3292	Two component regulator propeller
FKZ68_RS22665	COG3015	lipoprotein NlpE involved in copper resistance
FKZ68_RS22715	COG0428	transporter
FKZ68_RS22725	COG2375	cellular response to nickel ion
FKZ68_RS22725	COG1132	(ABC) transporter
FKZ68_RS22730	COG1132	(ABC) transporter
FKZ68_RS22750	COG4771	TonB-dependent receptor
FKZ68_RS22760	COG2801	Transposase and inactivated derivatives
FKZ68_RS22770	COG3385	transposase activity
FKZ68_RS22785	COG0622	Phosphoesterase
FKZ68_RS22940	COG0628	permease
FKZ68_RS22945	COG1215	transferase activity, transferring glycosyl groups
FKZ68_RS22950	COG0456	acetyltransferase
FKZ68_RS22955	COG0189	ligase activity
FKZ68_RS22955	COG0569	domain protein
FKZ68_RS22960	COG1136	(ABC) transporter
FKZ68_RS22960	COG0577	efflux transmembrane transporter activity
FKZ68_RS22965	COG0436	Aminotransferase
FKZ68_RS22980	COG0488	(ABC) transporter
FKZ68_RS22995	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS23060	COG4206	TonB-dependent receptor
FKZ68_RS23075	COG3033	Beta-eliminating lyase
FKZ68_RS23100	COG0629	single-stranded DNA binding
FKZ68_RS23105	COG1194	a g-specific adenine glycosylase
FKZ68_RS23115	COG1530	ribonuclease E activity
FKZ68_RS23135	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS23140	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS23215	COG1629	transport
FKZ68_RS23250	COG1120	ATPase activity
FKZ68_RS23255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKZ68_RS23325	COG1115	amino acid carrier protein
FKZ68_RS23340	COG1509	lysine 2,3-aminomutase activity
FKZ68_RS23385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKZ68_RS23405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKZ68_RS23410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FKZ68_RS23425	COG1595	DNA-templated transcription, initiation
FKZ68_RS23440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKZ68_RS23445	COG1741	Belongs to the pirin family
FKZ68_RS23450	COG0259	pyridoxamine-phosphate oxidase activity
FKZ68_RS23465	COG0346	lactoylglutathione lyase activity
FKZ68_RS23525	COG1918	ferrous iron import across plasma membrane
FKZ68_RS23525	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FKZ68_RS23530	COG0037	tRNA processing
FKZ68_RS23545	COG3119	arylsulfatase activity
FKZ68_RS23555	COG0534	Mate efflux family protein
FKZ68_RS23560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKZ68_RS23565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKZ68_RS23620	COG4372	Transposase
FKZ68_RS23625	COG3385	transposase activity
FKZ68_RS23665	COG1983	PspC domain protein
FKZ68_RS23670	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FKZ68_RS23695	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKZ68_RS23710	COG0668	transmembrane transport
FKZ68_RS23720	COG3250	beta-galactosidase activity
FKZ68_RS23725	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS23730	COG3119	arylsulfatase activity
FKZ68_RS23740	COG4771	TonB-dependent receptor
FKZ68_RS23775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FKZ68_RS23785	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS23785	COG2205	protein histidine kinase activity
FKZ68_RS23785	COG3292	Two component regulator propeller
FKZ68_RS23785	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS23785	COG2205	protein histidine kinase activity
FKZ68_RS23785	COG3292	Two component regulator propeller
FKZ68_RS23790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FKZ68_RS23795	COG1830	Aldolase
FKZ68_RS23800	COG0588	phosphoglycerate mutase activity
FKZ68_RS23815	COG1629	transport
FKZ68_RS23815	COG4206	TonB-dependent receptor
FKZ68_RS23860	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FKZ68_RS23895	COG1119	ATPase activity
FKZ68_RS23900	COG3661	Belongs to the glycosyl hydrolase 67 family
FKZ68_RS23915	COG2211	Major facilitator Superfamily
FKZ68_RS23935	COG0561	phosphatase activity
FKZ68_RS23940	COG1629	transport
FKZ68_RS23940	COG4206	TonB-dependent receptor
FKZ68_RS23950	COG1523	belongs to the glycosyl hydrolase 13 family
FKZ68_RS23955	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FKZ68_RS23995	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FKZ68_RS24005	COG2814	Major facilitator Superfamily
FKZ68_RS24010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKZ68_RS24015	COG0126	phosphoglycerate kinase activity
FKZ68_RS24030	COG2311	Membrane
FKZ68_RS24040	COG0424	maF-like protein
FKZ68_RS24060	COG0778	Nitroreductase
FKZ68_RS24070	COG0288	reversible hydration of carbon dioxide
FKZ68_RS24085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKZ68_RS24095	COG0511	ligase activity, forming carbon-carbon bonds
FKZ68_RS24100	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FKZ68_RS24110	COG0191	fructose-bisphosphate aldolase activity
FKZ68_RS24115	COG0254	rRNA binding
FKZ68_RS24120	COG1373	ATPase (AAA superfamily
FKZ68_RS24145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKZ68_RS24170	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FKZ68_RS24175	COG0511	ligase activity, forming carbon-carbon bonds
FKZ68_RS24215	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FKZ68_RS24230	COG1280	lysine exporter protein (LysE YggA)
FKZ68_RS24240	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS24240	COG3292	Two component regulator propeller
FKZ68_RS24240	COG3292	Two component regulator propeller
FKZ68_RS24240	COG2205	protein histidine kinase activity
FKZ68_RS24240	COG2205	protein histidine kinase activity
FKZ68_RS24240	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS24260	COG1649	PFAM Uncharacterised BCR, COG1649
FKZ68_RS24280	COG1966	Carbon starvation protein
FKZ68_RS24285	COG1649	PFAM Uncharacterised BCR, COG1649
FKZ68_RS24315	COG2113	Glycine betaine
FKZ68_RS24320	COG4176	ABC-type proline glycine betaine transport system permease component
FKZ68_RS24330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKZ68_RS24340	COG2205	protein histidine kinase activity
FKZ68_RS24340	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS24340	COG3292	Two component regulator propeller
FKZ68_RS24345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKZ68_RS24345	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FKZ68_RS24360	COG1621	beta-fructofuranosidase activity
FKZ68_RS24380	COG1629	transport
FKZ68_RS24390	COG1621	beta-fructofuranosidase activity
FKZ68_RS24400	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKZ68_RS24405	COG0475	glutathione-regulated potassium exporter activity
FKZ68_RS24475	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FKZ68_RS24480	COG1960	acyl-CoA dehydrogenase activity
FKZ68_RS24485	COG0705	Rhomboid family
FKZ68_RS24500	COG1956	GAF domain-containing protein
FKZ68_RS24510	COG0484	heat shock protein binding
FKZ68_RS24515	COG2194	sulfuric ester hydrolase activity
FKZ68_RS24535	COG0028	Belongs to the TPP enzyme family
FKZ68_RS24565	COG4974	Belongs to the 'phage' integrase family
FKZ68_RS24640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKZ68_RS24645	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS24655	COG4771	TonB-dependent receptor
FKZ68_RS24720	COG1120	ATPase activity
FKZ68_RS24725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKZ68_RS24780	COG0459	protein refolding
FKZ68_RS24785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FKZ68_RS24810	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FKZ68_RS24820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FKZ68_RS24870	COG0124	histidyl-tRNA synthetase
FKZ68_RS24885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKZ68_RS24910	COG0514	ATP-dependent DNA helicase (RecQ)
FKZ68_RS24920	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FKZ68_RS24925	COG1368	sulfuric ester hydrolase activity
FKZ68_RS24930	COG0671	phosphoesterase, PA-phosphatase related
FKZ68_RS24935	COG0473	3-isopropylmalate dehydrogenase activity
FKZ68_RS24945	COG0066	3-isopropylmalate dehydratase activity
FKZ68_RS24950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKZ68_RS24955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKZ68_RS25030	COG4977	sequence-specific DNA binding
FKZ68_RS25030	COG1917	Cupin 2, conserved barrel domain protein
FKZ68_RS25060	COG1028	Short-chain dehydrogenase reductase Sdr
FKZ68_RS25085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FKZ68_RS25100	COG3118	belongs to the thioredoxin family
FKZ68_RS25105	COG0439	Biotin carboxylase
FKZ68_RS25115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKZ68_RS25125	COG2873	o-acetylhomoserine
FKZ68_RS25130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FKZ68_RS25180	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKZ68_RS25190	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FKZ68_RS25195	COG1088	dTDP-glucose 4,6-dehydratase activity
FKZ68_RS25200	COG1575	Belongs to the MenA family. Type 1 subfamily
FKZ68_RS25205	COG1408	metallophosphoesterase
FKZ68_RS25215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FKZ68_RS25225	COG0194	GDP metabolic process
FKZ68_RS25245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKZ68_RS25250	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKZ68_RS25260	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FKZ68_RS25265	COG0750	zinc metalloprotease
FKZ68_RS25270	COG2814	Major facilitator Superfamily
FKZ68_RS25280	COG1328	CTP reductase activity
FKZ68_RS25290	COG1538	Outer membrane efflux protein
FKZ68_RS25360	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FKZ68_RS25375	COG0561	phosphatase activity
FKZ68_RS25380	COG4771	TonB-dependent receptor
FKZ68_RS25405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FKZ68_RS25450	COG1505	serine-type exopeptidase activity
FKZ68_RS25465	COG3119	arylsulfatase activity
FKZ68_RS25470	COG3119	arylsulfatase activity
FKZ68_RS25475	COG0617	tRNA 3'-terminal CCA addition
FKZ68_RS25490	COG0632	four-way junction helicase activity
FKZ68_RS25495	COG0673	inositol 2-dehydrogenase activity
FKZ68_RS25500	COG1272	protein, Hemolysin III
FKZ68_RS25525	COG1629	transport
FKZ68_RS25525	COG4206	TonB-dependent receptor
FKZ68_RS25530	COG1629	transport
FKZ68_RS25540	COG2204	response regulator
FKZ68_RS25545	COG0488	(ABC) transporter
FKZ68_RS25595	COG1595	DNA-templated transcription, initiation
FKZ68_RS25605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKZ68_RS25610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FKZ68_RS25620	COG1522	sequence-specific DNA binding
FKZ68_RS25650	COG0811	peptide transport
FKZ68_RS25660	COG0084	hydrolase, TatD family'
FKZ68_RS25680	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FKZ68_RS25685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FKZ68_RS25690	COG0205	6-phosphofructokinase activity
FKZ68_RS25735	COG0372	Belongs to the citrate synthase family
FKZ68_RS25745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKZ68_RS25750	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FKZ68_RS25760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FKZ68_RS25775	COG0028	Belongs to the TPP enzyme family
FKZ68_RS25780	COG0129	dihydroxy-acid dehydratase activity
FKZ68_RS25790	COG3681	Belongs to the UPF0597 family
FKZ68_RS25810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FKZ68_RS25885	COG4771	TonB-dependent receptor
FKZ68_RS25895	COG1595	DNA-templated transcription, initiation
FKZ68_RS25900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FKZ68_RS25900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FKZ68_RS25905	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FKZ68_RS25910	COG0569	domain protein
FKZ68_RS25910	COG2985	domain, Protein
FKZ68_RS25965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKZ68_RS26000	COG0702	epimerase
FKZ68_RS26005	COG4206	TonB-dependent receptor
FKZ68_RS26005	COG1629	transport
FKZ68_RS26010	COG1940	carbohydrate kinase activity
FKZ68_RS26020	COG2188	Transcriptional regulator
FKZ68_RS26070	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS26070	COG0745	RESPONSE REGULATOR receiver
FKZ68_RS26070	COG3292	Two component regulator propeller
FKZ68_RS26070	COG2205	protein histidine kinase activity
FKZ68_RS26070	COG2205	protein histidine kinase activity
FKZ68_RS26070	COG3292	Two component regulator propeller
FKZ68_RS26090	COG4206	TonB-dependent receptor
FKZ68_RS26090	COG1629	transport
FKZ68_RS26110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FKZ68_RS26120	COG3119	arylsulfatase activity
FKZ68_RS26140	COG3385	transposase activity
FKZ68_RS26170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FKZ68_RS26175	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FKZ68_RS26180	COG0166	Belongs to the GPI family
FKZ68_RS26195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKZ68_RS26210	COG2502	aspartate--ammonia ligase
FKZ68_RS26215	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FKZ68_RS26230	COG3876	Protein conserved in bacteria
FKZ68_RS26255	COG2315	Protein conserved in bacteria
FKZ68_RS26280	COG3340	Belongs to the peptidase S51 family
FKZ68_RS26285	COG2378	regulation of single-species biofilm formation
FKZ68_RS26320	COG0358	DNA primase activity
FKZ68_RS26350	COG0860	N-Acetylmuramoyl-L-alanine amidase
FKZ68_RS26410	COG1196	nuclear chromosome segregation
FKZ68_RS26410	COG0741	lytic transglycosylase activity
FKZ68_RS26410	COG0739	heme binding
FKZ68_RS26450	COG0776	regulation of translation
FKZ68_RS26595	COG4227	nucleotidyltransferase activity