locus-tag	class	description
FSW04_RS00005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSW04_RS00020	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS00035	COG1959	2 iron, 2 sulfur cluster binding
FSW04_RS00035	COG1295	ribonuclease BN
FSW04_RS00045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS00065	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FSW04_RS00070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS00085	COG2226	methyltransferase
FSW04_RS00090	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS00100	COG2197	response regulator
FSW04_RS00165	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS00165	COG1024	Enoyl-CoA hydratase
FSW04_RS00170	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS00210	COG0708	Exodeoxyribonuclease III
FSW04_RS00225	COG1672	PFAM Archaeal ATPase
FSW04_RS00225	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FSW04_RS00255	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FSW04_RS00265	COG0477	Major facilitator Superfamily
FSW04_RS00275	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS00280	COG0154	amidase activity
FSW04_RS00300	COG0640	Transcriptional regulator
FSW04_RS00340	COG0574	Belongs to the PEP-utilizing enzyme family
FSW04_RS00340	COG3848	Pyruvate phosphate dikinase
FSW04_RS00400	COG0477	Major facilitator Superfamily
FSW04_RS00405	COG1846	Transcriptional regulator
FSW04_RS00410	COG0613	PHP domain protein
FSW04_RS00415	COG1968	undecaprenyl-diphosphatase activity
FSW04_RS00440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FSW04_RS00450	COG0492	ferredoxin-NADP+ reductase activity
FSW04_RS00495	COG1309	transcriptional regulator
FSW04_RS00525	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FSW04_RS00575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSW04_RS00610	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FSW04_RS00700	COG1764	response to oxidative stress
FSW04_RS00705	COG0463	Glycosyl transferase, family 2
FSW04_RS00710	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSW04_RS00775	COG0463	Glycosyl transferase, family 2
FSW04_RS00830	COG2226	methyltransferase
FSW04_RS00835	COG0297	glycogen (starch) synthase activity
FSW04_RS00850	COG0500	methyltransferase
FSW04_RS00875	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FSW04_RS00880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS00890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS00905	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS00925	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS00930	COG1309	transcriptional regulator
FSW04_RS00935	COG2837	iron assimilation
FSW04_RS00945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSW04_RS00950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS00960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS00960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS00990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS01010	COG2423	ornithine cyclodeaminase activity
FSW04_RS01025	COG3795	YCII-related domain
FSW04_RS01030	COG4941	Belongs to the sigma-70 factor family
FSW04_RS01040	COG0175	sulfate reduction
FSW04_RS01045	COG0730	response to heat
FSW04_RS01070	COG0439	Biotin carboxylase
FSW04_RS01100	COG0045	succinate-CoA ligase (ADP-forming) activity
FSW04_RS01105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSW04_RS01130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSW04_RS01135	COG1321	iron dependent repressor
FSW04_RS01140	COG0583	DNA-binding transcription factor activity
FSW04_RS01150	COG1793	dna ligase
FSW04_RS01155	COG2364	Membrane
FSW04_RS01165	COG1929	Belongs to the glycerate kinase type-1 family
FSW04_RS01170	COG5001	Diguanylate cyclase
FSW04_RS01170	COG3300	MHYT domain
FSW04_RS01180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FSW04_RS01185	COG4251	negative regulation of phosphorylation
FSW04_RS01190	COG0784	Response regulator, receiver
FSW04_RS01195	COG1111	helicase
FSW04_RS01195	COG1205	dead DEAH box helicase
FSW04_RS01240	COG0439	Biotin carboxylase
FSW04_RS01245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSW04_RS01350	COG4221	oxidoreductase activity
FSW04_RS01360	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS01365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSW04_RS01370	COG2186	Transcriptional regulator
FSW04_RS01380	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FSW04_RS01400	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS01405	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS01410	COG0174	glutamine synthetase
FSW04_RS01415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSW04_RS01420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSW04_RS01425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FSW04_RS01460	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS01465	COG3794	PFAM blue (type 1) copper domain protein
FSW04_RS01475	COG3507	Belongs to the glycosyl hydrolase 43 family
FSW04_RS01495	COG0745	RESPONSE REGULATOR receiver
FSW04_RS01535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FSW04_RS01545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS01550	COG1024	Enoyl-CoA hydratase
FSW04_RS01555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSW04_RS01570	COG1309	transcriptional regulator
FSW04_RS01575	COG0784	Response regulator, receiver
FSW04_RS01575	COG3437	response regulator, receiver
FSW04_RS01600	COG2205	protein histidine kinase activity
FSW04_RS01600	COG2202	Pas domain
FSW04_RS01610	COG3437	response regulator, receiver
FSW04_RS01620	COG2017	converts alpha-aldose to the beta-anomer
FSW04_RS01625	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FSW04_RS01630	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS01705	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS01705	COG1024	Enoyl-CoA hydratase
FSW04_RS01710	COG0183	Belongs to the thiolase family
FSW04_RS01725	COG2814	Major facilitator Superfamily
FSW04_RS01770	COG0069	glutamate synthase activity
FSW04_RS01775	COG0028	Belongs to the TPP enzyme family
FSW04_RS01800	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS01840	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS01850	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS01860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS01890	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS01895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FSW04_RS01900	COG1335	isochorismatase
FSW04_RS01910	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS01915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS01920	COG1024	Enoyl-CoA hydratase
FSW04_RS01950	COG1937	Protein conserved in bacteria
FSW04_RS01965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS01970	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS02000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS02025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FSW04_RS02025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSW04_RS02030	COG0477	Major facilitator Superfamily
FSW04_RS02035	COG4106	trans-aconitate 2-methyltransferase activity
FSW04_RS02040	COG4221	oxidoreductase activity
FSW04_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS02075	COG2301	Belongs to the HpcH HpaI aldolase family
FSW04_RS02085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS02090	COG1309	transcriptional regulator
FSW04_RS02095	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS02105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS02125	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS02135	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS02140	COG1024	Enoyl-CoA hydratase
FSW04_RS02170	COG1024	Enoyl-CoA hydratase
FSW04_RS02200	COG1063	alcohol dehydrogenase
FSW04_RS02205	COG0671	phosphoesterase, PA-phosphatase related
FSW04_RS02215	COG1803	Methylglyoxal synthase
FSW04_RS02215	COG1597	lipid kinase activity
FSW04_RS02290	COG0252	asparaginase activity
FSW04_RS02320	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS02320	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS02325	COG1024	Enoyl-CoA hydratase
FSW04_RS02330	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS02330	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS02340	COG0022	dehydrogenase e1 component
FSW04_RS02395	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS02415	COG0596	Alpha beta hydrolase
FSW04_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS02425	COG0656	L-ascorbic acid biosynthetic process
FSW04_RS02440	COG2076	Multidrug Resistance protein
FSW04_RS02460	COG2130	NADP-dependent
FSW04_RS02480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSW04_RS02490	COG1609	Transcriptional regulator
FSW04_RS02515	COG0477	Major facilitator Superfamily
FSW04_RS02525	COG0697	spore germination
FSW04_RS02560	COG1091	dTDP-4-dehydrorhamnose reductase activity
FSW04_RS02575	COG1309	transcriptional regulator
FSW04_RS02585	COG1201	RNA secondary structure unwinding
FSW04_RS02590	COG0406	alpha-ribazole phosphatase activity
FSW04_RS02590	COG0494	nUDIX hydrolase
FSW04_RS02595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSW04_RS02600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSW04_RS02600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FSW04_RS02605	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSW04_RS02615	COG1917	Cupin 2, conserved barrel domain protein
FSW04_RS02660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSW04_RS02665	COG0459	protein refolding
FSW04_RS02670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSW04_RS02710	COG1309	transcriptional regulator
FSW04_RS02750	COG2151	metal-sulfur cluster biosynthetic enzyme
FSW04_RS02750	COG0489	protein tyrosine kinase activity
FSW04_RS02830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FSW04_RS02830	COG1796	DNA polymerase
FSW04_RS02835	COG0463	Glycosyl transferase, family 2
FSW04_RS02850	COG1595	DNA-templated transcription, initiation
FSW04_RS02855	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FSW04_RS02860	COG3118	belongs to the thioredoxin family
FSW04_RS02865	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FSW04_RS02900	COG2326	polyphosphate kinase activity
FSW04_RS02910	COG0534	Mate efflux family protein
FSW04_RS02920	COG0114	fumarate hydratase activity
FSW04_RS02955	COG2247	cell wall binding repeat
FSW04_RS02955	COG2385	sporulation resulting in formation of a cellular spore
FSW04_RS02970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSW04_RS02980	COG3250	beta-galactosidase activity
FSW04_RS03000	COG0012	GTP binding
FSW04_RS03010	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FSW04_RS03020	COG1045	serine acetyltransferase
FSW04_RS03030	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FSW04_RS03035	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FSW04_RS03060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSW04_RS03075	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS03080	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS03090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSW04_RS03100	COG1045	serine acetyltransferase
FSW04_RS03140	COG4555	ABC transporter
FSW04_RS03145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSW04_RS03150	COG0346	lactoylglutathione lyase activity
FSW04_RS03160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSW04_RS03165	COG2353	YceI-like domain
FSW04_RS03185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSW04_RS03190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FSW04_RS03195	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS03205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSW04_RS03205	COG1648	precorrin-2 dehydrogenase activity
FSW04_RS03210	COG0315	cyclic pyranopterin monophosphate synthase activity
FSW04_RS03225	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FSW04_RS03240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FSW04_RS03245	COG0181	hydroxymethylbilane synthase activity
FSW04_RS03250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FSW04_RS03250	COG1648	precorrin-2 dehydrogenase activity
FSW04_RS03260	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FSW04_RS03260	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FSW04_RS03270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSW04_RS03285	COG1490	D-aminoacyl-tRNA deacylase activity
FSW04_RS03295	COG0778	Nitroreductase
FSW04_RS03305	COG4608	Belongs to the ABC transporter superfamily
FSW04_RS03320	COG4166	transmembrane transport
FSW04_RS03325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSW04_RS03335	COG0784	Response regulator, receiver
FSW04_RS03340	COG4251	negative regulation of phosphorylation
FSW04_RS03355	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSW04_RS03380	COG0668	transmembrane transport
FSW04_RS03385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSW04_RS03390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSW04_RS03395	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FSW04_RS03410	COG0745	RESPONSE REGULATOR receiver
FSW04_RS03415	COG5002	protein histidine kinase activity
FSW04_RS03420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS03435	COG0360	Binds together with S18 to 16S ribosomal RNA
FSW04_RS03440	COG0629	single-stranded DNA binding
FSW04_RS03450	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FSW04_RS03455	COG0359	binds to the 23S rRNA
FSW04_RS03460	COG0305	Participates in initiation and elongation during chromosome replication
FSW04_RS03470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FSW04_RS03475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSW04_RS03510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS03520	COG0577	efflux transmembrane transporter activity
FSW04_RS03520	COG1136	(ABC) transporter
FSW04_RS03530	COG1063	alcohol dehydrogenase
FSW04_RS03570	COG0145	ligase activity
FSW04_RS03585	COG0287	Prephenate dehydrogenase
FSW04_RS03590	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS03595	COG0022	dehydrogenase e1 component
FSW04_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS03610	COG2226	methyltransferase
FSW04_RS03615	COG1335	isochorismatase
FSW04_RS03625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS03635	COG1024	Enoyl-CoA hydratase
FSW04_RS03640	COG3321	synthase
FSW04_RS03640	COG0604	alcohol dehydrogenase
FSW04_RS03655	COG0805	protein transport
FSW04_RS03660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSW04_RS03675	COG2226	methyltransferase
FSW04_RS03700	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FSW04_RS03705	COG1522	sequence-specific DNA binding
FSW04_RS03710	COG0113	porphobilinogen synthase activity
FSW04_RS03715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FSW04_RS03725	COG0628	permease
FSW04_RS03730	COG1692	metallophosphoesterase
FSW04_RS03770	COG2205	protein histidine kinase activity
FSW04_RS03785	COG1192	Involved in chromosome partitioning
FSW04_RS03790	COG0357	Ribosomal RNA small subunit methyltransferase G
FSW04_RS03805	COG1847	R3H domain protein
FSW04_RS03810	COG0706	membrane insertase activity
FSW04_RS03815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FSW04_RS03820	COG0594	ribonuclease P activity
FSW04_RS03825	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FSW04_RS03830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FSW04_RS03835	COG0592	DNA-directed DNA polymerase activity
FSW04_RS03840	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FSW04_RS03850	COG0187	DNA topoisomerase II activity
FSW04_RS03855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FSW04_RS03865	COG0077	Prephenate dehydratase
FSW04_RS03890	COG1716	ATPase activity
FSW04_RS03895	COG0631	protein serine/threonine phosphatase activity
FSW04_RS03900	COG0772	Belongs to the SEDS family
FSW04_RS03905	COG0768	penicillin binding
FSW04_RS03910	COG0515	serine threonine protein kinase
FSW04_RS03915	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSW04_RS03920	COG1793	dna ligase
FSW04_RS03920	COG3285	dna ligase
FSW04_RS03925	COG0515	serine threonine protein kinase
FSW04_RS03925	COG2815	serine threonine protein kinase
FSW04_RS03930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FSW04_RS03935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FSW04_RS03940	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FSW04_RS03945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FSW04_RS03950	COG4786	Flagellar basal body rod
FSW04_RS03950	COG1256	bacterial-type flagellum assembly
FSW04_RS03970	COG4786	Flagellar basal body rod
FSW04_RS03980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FSW04_RS03990	COG0463	Glycosyl transferase, family 2
FSW04_RS03990	COG0457	Tetratricopeptide repeat
FSW04_RS04000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FSW04_RS04015	COG1815	bacterial-type flagellum-dependent cell motility
FSW04_RS04035	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FSW04_RS04045	COG1157	protein secretion by the type III secretion system
FSW04_RS04055	COG0739	heme binding
FSW04_RS04055	COG0741	lytic transglycosylase activity
FSW04_RS04055	COG1196	nuclear chromosome segregation
FSW04_RS04075	COG4786	Flagellar basal body rod
FSW04_RS04085	COG0835	chemotaxis
FSW04_RS04090	COG2201	protein-glutamate methylesterase activity
FSW04_RS04095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FSW04_RS04100	COG2198	Histidine kinase
FSW04_RS04100	COG0643	Histidine kinase
FSW04_RS04105	COG1776	CheC inhibitor of MCP methylation
FSW04_RS04110	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FSW04_RS04125	COG2201	protein-glutamate methylesterase activity
FSW04_RS04135	COG1360	Flagellar Motor Protein
FSW04_RS04155	COG1338	Plays a role in the flagellum-specific transport system
FSW04_RS04165	COG1684	flagellar biosynthetic protein fliR
FSW04_RS04170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FSW04_RS04175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FSW04_RS04195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FSW04_RS04215	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FSW04_RS04220	COG1968	undecaprenyl-diphosphatase activity
FSW04_RS04225	COG0586	Pfam SNARE associated Golgi protein
FSW04_RS04250	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS04285	COG1809	phosphosulfolactate synthase activity
FSW04_RS04310	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS04335	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSW04_RS04345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSW04_RS04350	COG0736	holo-[acyl-carrier-protein] synthase activity
FSW04_RS04355	COG0297	glycogen (starch) synthase activity
FSW04_RS04360	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS04365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSW04_RS04370	COG1181	Belongs to the D-alanine--D-alanine ligase family
FSW04_RS04390	COG0596	Alpha beta hydrolase
FSW04_RS04415	COG3268	Saccharopine dehydrogenase
FSW04_RS04430	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS04445	COG2072	flavoprotein involved in K transport
FSW04_RS04450	COG4941	Belongs to the sigma-70 factor family
FSW04_RS04480	COG0384	phenazine biosynthesis protein PhzF
FSW04_RS04515	COG0384	phenazine biosynthesis protein PhzF
FSW04_RS04525	COG1131	(ABC) transporter
FSW04_RS04535	COG4152	abc transporter atp-binding protein
FSW04_RS04550	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS04555	COG1192	Involved in chromosome partitioning
FSW04_RS04575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSW04_RS04590	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS04595	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS04605	COG1686	Belongs to the peptidase S11 family
FSW04_RS04615	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FSW04_RS04625	COG0321	lipoyl(octanoyl) transferase activity
FSW04_RS04640	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS04645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS04645	COG0022	dehydrogenase e1 component
FSW04_RS04650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS04675	COG0352	thiamine-phosphate diphosphorylase activity
FSW04_RS04680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSW04_RS04690	COG2022	thiamine diphosphate biosynthetic process
FSW04_RS04725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FSW04_RS04755	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS04760	COG2814	Major facilitator Superfamily
FSW04_RS04775	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FSW04_RS04795	COG0006	proline dipeptidase activity
FSW04_RS04800	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FSW04_RS04845	COG0587	DNA-directed DNA polymerase activity
FSW04_RS04855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSW04_RS04890	COG0443	Heat shock 70 kDa protein
FSW04_RS04900	COG0484	heat shock protein binding
FSW04_RS04905	COG0789	Transcriptional regulator
FSW04_RS04920	COG0542	response to heat
FSW04_RS04930	COG4274	PFAM GYD family protein
FSW04_RS04935	COG0151	Belongs to the GarS family
FSW04_RS04940	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FSW04_RS04945	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FSW04_RS04960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FSW04_RS04965	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSW04_RS04975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FSW04_RS04985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FSW04_RS05005	COG0138	bifunctional purine biosynthesis protein purh
FSW04_RS05015	COG1061	Type III restriction enzyme res subunit
FSW04_RS05055	COG4974	Belongs to the 'phage' integrase family
FSW04_RS05075	COG3158	transport of potassium into the cell
FSW04_RS05095	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FSW04_RS05100	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FSW04_RS05110	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FSW04_RS05115	COG1492	cobalamin metabolic process
FSW04_RS05140	COG1797	cobyrinic acid a,c-diamide synthase activity
FSW04_RS05240	COG0596	Alpha beta hydrolase
FSW04_RS05250	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS05255	COG4941	Belongs to the sigma-70 factor family
FSW04_RS05280	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS05285	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS05290	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS05295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS05305	COG2226	methyltransferase
FSW04_RS05360	COG1295	ribonuclease BN
FSW04_RS05390	COG1280	lysine exporter protein (LysE YggA)
FSW04_RS05400	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FSW04_RS05405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FSW04_RS05430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FSW04_RS05445	COG2205	protein histidine kinase activity
FSW04_RS05445	COG0784	Response regulator, receiver
FSW04_RS05450	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS05450	COG2172	sigma factor antagonist activity
FSW04_RS05450	COG2208	phosphoserine phosphatase activity
FSW04_RS05490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FSW04_RS05515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FSW04_RS05525	COG2197	response regulator
FSW04_RS05535	COG1363	Peptidase, m42
FSW04_RS05540	COG0546	phosphoglycolate phosphatase activity
FSW04_RS05560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FSW04_RS05590	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
FSW04_RS05595	COG4935	Belongs to the peptidase S8 family
FSW04_RS05595	COG2234	aminopeptidase activity
FSW04_RS05635	COG0567	Dehydrogenase, E1 component
FSW04_RS05640	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS05640	COG0567	Dehydrogenase, E1 component
FSW04_RS05670	COG0183	Belongs to the thiolase family
FSW04_RS05675	COG0277	FAD linked oxidase domain protein
FSW04_RS05695	COG5001	Diguanylate cyclase
FSW04_RS05700	COG0248	Ppx GppA phosphatase
FSW04_RS05720	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FSW04_RS05725	COG0398	Pfam SNARE associated Golgi protein
FSW04_RS05745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS05755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FSW04_RS05800	COG0667	Aldo Keto reductase
FSW04_RS05815	COG0372	Belongs to the citrate synthase family
FSW04_RS05830	COG0717	Belongs to the dCTP deaminase family
FSW04_RS05860	COG0513	Belongs to the DEAD box helicase family
FSW04_RS05870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FSW04_RS05875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FSW04_RS05880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSW04_RS05885	COG2188	Transcriptional regulator
FSW04_RS05900	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS05905	COG0745	RESPONSE REGULATOR receiver
FSW04_RS05910	COG3437	response regulator, receiver
FSW04_RS05920	COG5002	protein histidine kinase activity
FSW04_RS05965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSW04_RS05970	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSW04_RS05990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FSW04_RS06020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS06025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FSW04_RS06025	COG1042	CoA-binding domain protein
FSW04_RS06025	COG0045	succinate-CoA ligase (ADP-forming) activity
FSW04_RS06030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS06050	COG0300	oxidoreductase activity
FSW04_RS06065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSW04_RS06070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSW04_RS06075	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS06080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSW04_RS06085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FSW04_RS06090	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FSW04_RS06095	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FSW04_RS06105	COG4208	sulfate ABC transporter
FSW04_RS06110	COG3842	ATPase activity
FSW04_RS06125	COG1007	ATP synthesis coupled electron transport
FSW04_RS06140	COG0713	ATP synthesis coupled electron transport
FSW04_RS06150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSW04_RS06155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FSW04_RS06160	COG1034	ATP synthesis coupled electron transport
FSW04_RS06175	COG0649	NAD binding
FSW04_RS06180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSW04_RS06185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSW04_RS06190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSW04_RS06200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FSW04_RS06215	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FSW04_RS06250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSW04_RS06275	COG2072	flavoprotein involved in K transport
FSW04_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS06285	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS06290	COG1024	Enoyl-CoA hydratase
FSW04_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS06305	COG1309	transcriptional regulator
FSW04_RS06320	COG2814	Major facilitator Superfamily
FSW04_RS06325	COG1846	Transcriptional regulator
FSW04_RS06345	COG0667	Aldo Keto reductase
FSW04_RS06375	COG2423	ornithine cyclodeaminase activity
FSW04_RS06390	COG1252	NADH dehydrogenase
FSW04_RS06400	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS06415	COG0640	Transcriptional regulator
FSW04_RS06440	COG2072	flavoprotein involved in K transport
FSW04_RS06445	COG1309	transcriptional regulator
FSW04_RS06450	COG2843	Capsule synthesis protein
FSW04_RS06490	COG3903	Transcriptional regulator
FSW04_RS06490	COG3629	intracellular signal transduction
FSW04_RS06495	COG2409	Drug exporters of the RND superfamily
FSW04_RS06510	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS06515	COG2267	carboxylic ester hydrolase activity
FSW04_RS06520	COG2226	methyltransferase
FSW04_RS06545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS06550	COG1335	isochorismatase
FSW04_RS06575	COG2188	Transcriptional regulator
FSW04_RS06615	COG1074	ATP-dependent DNA helicase activity
FSW04_RS06635	COG1111	helicase
FSW04_RS06635	COG1205	dead DEAH box helicase
FSW04_RS06645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FSW04_RS06660	COG0582	viral genome integration into host DNA
FSW04_RS06690	COG1131	(ABC) transporter
FSW04_RS06710	COG0300	oxidoreductase activity
FSW04_RS06745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FSW04_RS06750	COG3001	Fructosamine kinase
FSW04_RS06810	COG1073	alpha beta
FSW04_RS06825	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS06830	COG3944	biosynthesis protein
FSW04_RS06840	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS06855	COG4464	protein tyrosine phosphatase activity
FSW04_RS06860	COG1404	Belongs to the peptidase S8 family
FSW04_RS06895	COG2030	dehydratase
FSW04_RS06900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSW04_RS06920	COG0346	lactoylglutathione lyase activity
FSW04_RS06940	COG1309	transcriptional regulator
FSW04_RS06950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FSW04_RS06960	COG2873	o-acetylhomoserine
FSW04_RS06965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSW04_RS06975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS06980	COG4221	oxidoreductase activity
FSW04_RS06990	COG2309	aminopeptidase activity
FSW04_RS07010	COG0484	heat shock protein binding
FSW04_RS07060	COG2197	response regulator
FSW04_RS07070	COG2409	Drug exporters of the RND superfamily
FSW04_RS07085	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS07090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FSW04_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS07110	COG0400	carboxylic ester hydrolase activity
FSW04_RS07115	COG0346	lactoylglutathione lyase activity
FSW04_RS07125	COG2203	Gaf domain
FSW04_RS07125	COG2199	diguanylate cyclase activity
FSW04_RS07130	COG2200	EAL domain
FSW04_RS07130	COG2199	diguanylate cyclase activity
FSW04_RS07145	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FSW04_RS07150	COG2188	Transcriptional regulator
FSW04_RS07155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS07165	COG2030	dehydratase
FSW04_RS07190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FSW04_RS07195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FSW04_RS07200	COG0247	lactate metabolic process
FSW04_RS07210	COG0277	FAD linked oxidase domain protein
FSW04_RS07240	COG0145	ligase activity
FSW04_RS07250	COG1309	transcriptional regulator
FSW04_RS07255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSW04_RS07260	COG0277	FAD linked oxidase domain protein
FSW04_RS07265	COG0277	FAD linked oxidase domain protein
FSW04_RS07270	COG0028	Belongs to the TPP enzyme family
FSW04_RS07280	COG3835	regulator
FSW04_RS07285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FSW04_RS07295	COG0831	urea catabolic process
FSW04_RS07305	COG0804	urea catabolic process
FSW04_RS07320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSW04_RS07325	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSW04_RS07340	COG2814	Major facilitator Superfamily
FSW04_RS07365	COG0028	Belongs to the TPP enzyme family
FSW04_RS07385	COG4948	Mandelate Racemase Muconate Lactonizing
FSW04_RS07400	COG1063	alcohol dehydrogenase
FSW04_RS07415	COG0145	ligase activity
FSW04_RS07460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSW04_RS07485	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSW04_RS07485	COG1136	(ABC) transporter
FSW04_RS07490	COG1136	(ABC) transporter
FSW04_RS07490	COG0577	efflux transmembrane transporter activity
FSW04_RS07500	COG3189	MarR family transcriptional regulator
FSW04_RS07535	COG0435	Glutathione S-transferase
FSW04_RS07570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FSW04_RS07575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FSW04_RS07590	COG0577	efflux transmembrane transporter activity
FSW04_RS07590	COG1136	(ABC) transporter
FSW04_RS07610	COG2048	Heterodisulfide reductase, subunit B
FSW04_RS07615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FSW04_RS07620	COG1053	succinate dehydrogenase
FSW04_RS07630	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FSW04_RS07640	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS07645	COG1309	transcriptional regulator
FSW04_RS07655	COG0039	L-malate dehydrogenase activity
FSW04_RS07695	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FSW04_RS07715	COG0423	glycine-tRNA ligase activity
FSW04_RS07725	COG1316	TRANSCRIPTIONal
FSW04_RS07730	COG1940	carbohydrate kinase activity
FSW04_RS07735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FSW04_RS07745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSW04_RS07750	COG0084	hydrolase, TatD family'
FSW04_RS07755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSW04_RS07760	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FSW04_RS07765	COG0586	Pfam SNARE associated Golgi protein
FSW04_RS07775	COG2508	Transcriptional regulator
FSW04_RS07775	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FSW04_RS07805	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FSW04_RS07810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSW04_RS07850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FSW04_RS07855	COG0193	aminoacyl-tRNA hydrolase activity
FSW04_RS07865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FSW04_RS07870	COG3956	TIGRFAM MazG family protein
FSW04_RS07875	COG0148	phosphopyruvate hydratase activity
FSW04_RS07900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FSW04_RS07915	COG1830	Aldolase
FSW04_RS07920	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSW04_RS07935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FSW04_RS07960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSW04_RS07960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FSW04_RS07980	COG1733	regulation of RNA biosynthetic process
FSW04_RS08015	COG0697	spore germination
FSW04_RS08040	COG2205	protein histidine kinase activity
FSW04_RS08045	COG0745	RESPONSE REGULATOR receiver
FSW04_RS08060	COG2353	YceI-like domain
FSW04_RS08065	COG1595	DNA-templated transcription, initiation
FSW04_RS08085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS08095	COG1063	alcohol dehydrogenase
FSW04_RS08110	COG0583	DNA-binding transcription factor activity
FSW04_RS08115	COG1454	alcohol dehydrogenase
FSW04_RS08115	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS08135	COG1672	PFAM Archaeal ATPase
FSW04_RS08135	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FSW04_RS08160	COG1322	Protein conserved in bacteria
FSW04_RS08195	COG1335	isochorismatase
FSW04_RS08200	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSW04_RS08205	COG0084	hydrolase, TatD family'
FSW04_RS08225	COG0386	Belongs to the glutathione peroxidase family
FSW04_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS08270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSW04_RS08290	COG1968	undecaprenyl-diphosphatase activity
FSW04_RS08295	COG0745	RESPONSE REGULATOR receiver
FSW04_RS08300	COG2205	protein histidine kinase activity
FSW04_RS08315	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FSW04_RS08325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FSW04_RS08330	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FSW04_RS08335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FSW04_RS08340	COG1744	ABC transporter substrate-binding protein PnrA-like
FSW04_RS08345	COG3845	ABC transporter
FSW04_RS08355	COG1079	Belongs to the binding-protein-dependent transport system permease family
FSW04_RS08365	COG2172	sigma factor antagonist activity
FSW04_RS08375	COG1522	sequence-specific DNA binding
FSW04_RS08380	COG3180	Ammonia monooxygenase
FSW04_RS08385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FSW04_RS08410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSW04_RS08465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSW04_RS08475	COG1640	4-alpha-glucanotransferase
FSW04_RS08480	COG0366	Alpha amylase catalytic
FSW04_RS08485	COG3281	Trehalose synthase
FSW04_RS08540	COG1959	2 iron, 2 sulfur cluster binding
FSW04_RS08550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSW04_RS08555	COG0822	iron-sulfur transferase activity
FSW04_RS08565	COG1217	gtp-binding protein TYPA
FSW04_RS08570	COG0277	FAD linked oxidase domain protein
FSW04_RS08585	COG2146	nitrite reductase [NAD(P)H] activity
FSW04_RS08590	COG0719	Fe-S assembly protein
FSW04_RS08595	COG0719	Fe-S assembly protein
FSW04_RS08600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FSW04_RS08615	COG1611	Belongs to the LOG family
FSW04_RS08630	COG1191	sigma factor activity
FSW04_RS08635	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS08640	COG1278	Cold shock
FSW04_RS08650	COG0076	glutamate decarboxylase activity
FSW04_RS08695	COG0753	catalase activity
FSW04_RS08705	COG0183	Belongs to the thiolase family
FSW04_RS08725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FSW04_RS08730	COG0247	lactate metabolic process
FSW04_RS08735	COG1139	Iron-sulfur cluster binding protein
FSW04_RS08740	COG1556	Lactate utilization protein
FSW04_RS08745	COG3387	PFAM Glycoside hydrolase 15-related
FSW04_RS08755	COG0406	alpha-ribazole phosphatase activity
FSW04_RS08760	COG0363	glucosamine-6-phosphate deaminase activity
FSW04_RS08765	COG3387	PFAM Glycoside hydrolase 15-related
FSW04_RS08780	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FSW04_RS08790	COG1940	carbohydrate kinase activity
FSW04_RS08795	COG1595	DNA-templated transcription, initiation
FSW04_RS08820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSW04_RS08840	COG0702	epimerase
FSW04_RS08850	COG0303	'Molybdopterin
FSW04_RS08860	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FSW04_RS08870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSW04_RS08885	COG1733	regulation of RNA biosynthetic process
FSW04_RS08925	COG1192	Involved in chromosome partitioning
FSW04_RS08930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSW04_RS08940	COG0405	Gamma-glutamyltransferase
FSW04_RS08965	COG0415	Belongs to the DNA photolyase family
FSW04_RS08970	COG2226	methyltransferase
FSW04_RS09005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FSW04_RS09010	COG0183	Belongs to the thiolase family
FSW04_RS09030	COG4585	Histidine kinase
FSW04_RS09035	COG3263	regulation of cellular component size
FSW04_RS09050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS09060	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FSW04_RS09065	COG0644	oxidoreductase
FSW04_RS09065	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FSW04_RS09075	COG0254	rRNA binding
FSW04_RS09080	COG3872	metal-dependent enzyme
FSW04_RS09085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FSW04_RS09090	COG2890	protein-(glutamine-N5) methyltransferase activity
FSW04_RS09100	COG0698	ribose 5-phosphate isomerase
FSW04_RS09105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FSW04_RS09120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSW04_RS09160	COG2514	catechol 2,3-dioxygenase activity
FSW04_RS09170	COG0356	it plays a direct role in the translocation of protons across the membrane
FSW04_RS09185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FSW04_RS09190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FSW04_RS09200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FSW04_RS09215	COG3268	Saccharopine dehydrogenase
FSW04_RS09220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSW04_RS09225	COG1316	TRANSCRIPTIONal
FSW04_RS09230	COG1316	TRANSCRIPTIONal
FSW04_RS09235	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FSW04_RS09240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FSW04_RS09245	COG2222	sugar isomerase
FSW04_RS09255	COG0789	Transcriptional regulator
FSW04_RS09260	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSW04_RS09265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FSW04_RS09290	COG0653	protein targeting
FSW04_RS09295	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FSW04_RS09300	COG1982	Orn Lys Arg decarboxylase major
FSW04_RS09310	COG0542	response to heat
FSW04_RS09350	COG0612	Peptidase, M16
FSW04_RS09355	COG2884	Cell division ATP-binding protein ftsE
FSW04_RS09360	COG2177	Part of the ABC transporter FtsEX involved in
FSW04_RS09365	COG0793	Belongs to the peptidase S41A family
FSW04_RS09370	COG0557	exoribonuclease II activity
FSW04_RS09375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FSW04_RS09425	COG1794	racemase activity, acting on amino acids and derivatives
FSW04_RS09485	COG2130	NADP-dependent
FSW04_RS09495	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS09500	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS09505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FSW04_RS09535	COG1940	carbohydrate kinase activity
FSW04_RS09555	COG1393	Belongs to the ArsC family
FSW04_RS09560	COG0596	Alpha beta hydrolase
FSW04_RS09580	COG0500	methyltransferase
FSW04_RS09585	COG0463	Glycosyl transferase, family 2
FSW04_RS09590	COG0406	alpha-ribazole phosphatase activity
FSW04_RS09600	COG4251	negative regulation of phosphorylation
FSW04_RS09620	COG1131	(ABC) transporter
FSW04_RS09630	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FSW04_RS09650	COG0123	including yeast histone deacetylase and acetoin utilization protein
FSW04_RS09655	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
FSW04_RS09670	COG1024	Enoyl-CoA hydratase
FSW04_RS09680	COG1024	Enoyl-CoA hydratase
FSW04_RS09695	COG0488	(ABC) transporter
FSW04_RS09705	COG0393	Putative heavy-metal-binding
FSW04_RS09710	COG0393	Putative heavy-metal-binding
FSW04_RS09715	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS09720	COG0297	glycogen (starch) synthase activity
FSW04_RS09735	COG2226	methyltransferase
FSW04_RS09740	COG0798	PFAM Bile acid sodium symporter
FSW04_RS09750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FSW04_RS09780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSW04_RS09785	COG0581	inorganic phosphate transmembrane transporter activity
FSW04_RS09790	COG0573	inorganic phosphate transmembrane transporter activity
FSW04_RS09795	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FSW04_RS09800	COG1392	Phosphate transport regulator
FSW04_RS09805	COG0745	RESPONSE REGULATOR receiver
FSW04_RS09810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FSW04_RS09815	COG0573	inorganic phosphate transmembrane transporter activity
FSW04_RS09820	COG0581	inorganic phosphate transmembrane transporter activity
FSW04_RS09825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FSW04_RS09830	COG0704	Plays a role in the regulation of phosphate uptake
FSW04_RS09835	COG0745	RESPONSE REGULATOR receiver
FSW04_RS09935	COG0741	lytic transglycosylase activity
FSW04_RS09960	COG3706	GGDEF domain
FSW04_RS09980	COG0322	excinuclease ABC activity
FSW04_RS09985	COG0517	IMP dehydrogenase activity
FSW04_RS09985	COG1227	inorganic diphosphatase activity
FSW04_RS09995	COG1660	Displays ATPase and GTPase activities
FSW04_RS10010	COG0126	phosphoglycerate kinase activity
FSW04_RS10015	COG0149	triose-phosphate isomerase activity
FSW04_RS10020	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FSW04_RS10035	COG1846	Transcriptional regulator
FSW04_RS10055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSW04_RS10065	COG0071	Belongs to the small heat shock protein (HSP20) family
FSW04_RS10070	COG0343	queuine tRNA-ribosyltransferase activity
FSW04_RS10080	COG0515	serine threonine protein kinase
FSW04_RS10080	COG2815	serine threonine protein kinase
FSW04_RS10100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FSW04_RS10110	COG0018	arginyl-trna synthetase
FSW04_RS10115	COG0785	Cytochrome C biogenesis protein
FSW04_RS10125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FSW04_RS10135	COG0582	viral genome integration into host DNA
FSW04_RS10215	COG1191	sigma factor activity
FSW04_RS10220	COG1191	sigma factor activity
FSW04_RS10230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSW04_RS10235	COG0297	glycogen (starch) synthase activity
FSW04_RS10260	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FSW04_RS10285	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS10290	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSW04_RS10295	COG2920	part of a sulfur-relay system
FSW04_RS10300	COG2210	Belongs to the sulfur carrier protein TusA family
FSW04_RS10330	COG2385	sporulation resulting in formation of a cellular spore
FSW04_RS10335	COG3511	phospholipase C
FSW04_RS10340	COG1067	ATP-dependent peptidase activity
FSW04_RS10345	COG0297	glycogen (starch) synthase activity
FSW04_RS10370	COG2226	methyltransferase
FSW04_RS10390	COG1191	sigma factor activity
FSW04_RS10400	COG5002	protein histidine kinase activity
FSW04_RS10400	COG5001	Diguanylate cyclase
FSW04_RS10415	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS10420	COG2124	cytochrome p450
FSW04_RS10430	COG1064	alcohol dehydrogenase
FSW04_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS10465	COG0450	alkyl hydroperoxide reductase
FSW04_RS10485	COG0628	permease
FSW04_RS10505	COG0776	regulation of translation
FSW04_RS10510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSW04_RS10565	COG1477	protein flavinylation
FSW04_RS10595	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS10645	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS10655	COG0604	alcohol dehydrogenase
FSW04_RS10665	COG0604	alcohol dehydrogenase
FSW04_RS10705	COG1522	sequence-specific DNA binding
FSW04_RS10720	COG2197	response regulator
FSW04_RS10735	COG0011	TIGRFAM Protein of
FSW04_RS10745	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FSW04_RS10750	COG1138	Cytochrome C-type biogenesis protein
FSW04_RS10770	COG3634	alkyl hydroperoxide reductase activity
FSW04_RS10780	COG4191	Histidine kinase
FSW04_RS10810	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FSW04_RS10820	COG0697	spore germination
FSW04_RS10825	COG0697	spore germination
FSW04_RS10835	COG0583	DNA-binding transcription factor activity
FSW04_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS10915	COG2072	flavoprotein involved in K transport
FSW04_RS10935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FSW04_RS10980	COG0587	DNA-directed DNA polymerase activity
FSW04_RS11000	COG1733	regulation of RNA biosynthetic process
FSW04_RS11005	COG0174	glutamine synthetase
FSW04_RS11010	COG2409	Drug exporters of the RND superfamily
FSW04_RS11015	COG1331	Highly conserved protein containing a thioredoxin domain
FSW04_RS11030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FSW04_RS11040	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS11045	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS11050	COG0531	amino acid
FSW04_RS11055	COG3263	regulation of cellular component size
FSW04_RS11060	COG2186	Transcriptional regulator
FSW04_RS11065	COG0174	glutamine synthetase
FSW04_RS11080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FSW04_RS11095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS11105	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS11120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FSW04_RS11130	COG2957	Belongs to the agmatine deiminase family
FSW04_RS11140	COG0831	urea catabolic process
FSW04_RS11140	COG0832	Belongs to the urease beta subunit family
FSW04_RS11145	COG0804	urea catabolic process
FSW04_RS11165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSW04_RS11175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FSW04_RS11180	COG0045	succinate-CoA ligase (ADP-forming) activity
FSW04_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11225	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11240	COG1024	Enoyl-CoA hydratase
FSW04_RS11255	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS11260	COG0145	ligase activity
FSW04_RS11275	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FSW04_RS11300	COG1172	Belongs to the binding-protein-dependent transport system permease family
FSW04_RS11305	COG1129	ABC transporter
FSW04_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS11330	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11335	COG1309	transcriptional regulator
FSW04_RS11340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS11345	COG0022	dehydrogenase e1 component
FSW04_RS11345	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS11350	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS11355	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS11385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS11395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11460	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11485	COG2203	Gaf domain
FSW04_RS11485	COG4585	Histidine kinase
FSW04_RS11515	COG2267	carboxylic ester hydrolase activity
FSW04_RS11520	COG2301	Belongs to the HpcH HpaI aldolase family
FSW04_RS11560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FSW04_RS11570	COG1573	uracil-dna glycosylase
FSW04_RS11575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS11595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS11595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS11610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FSW04_RS11620	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS11630	COG0604	alcohol dehydrogenase
FSW04_RS11635	COG0598	Magnesium transport protein CorA
FSW04_RS11640	COG0477	Major facilitator Superfamily
FSW04_RS11680	COG1321	iron dependent repressor
FSW04_RS11685	COG1914	H( )-stimulated, divalent metal cation uptake system
FSW04_RS11700	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FSW04_RS11710	COG0778	Nitroreductase
FSW04_RS11710	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
FSW04_RS11715	COG1920	GTP binding
FSW04_RS11720	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FSW04_RS11740	COG1024	Enoyl-CoA hydratase
FSW04_RS11760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS11815	COG0456	acetyltransferase
FSW04_RS11865	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS11885	COG3620	sequence-specific DNA binding
FSW04_RS11890	COG4974	Belongs to the 'phage' integrase family
FSW04_RS11900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FSW04_RS11930	COG0038	chloride channel
FSW04_RS11940	COG2226	methyltransferase
FSW04_RS11955	COG2814	Major facilitator Superfamily
FSW04_RS11990	COG2271	Major facilitator Superfamily
FSW04_RS12005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSW04_RS12010	COG1845	cytochrome c oxidase, subunit III
FSW04_RS12030	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FSW04_RS12050	COG0247	lactate metabolic process
FSW04_RS12050	COG0277	FAD linked oxidase domain protein
FSW04_RS12065	COG3619	membrane
FSW04_RS12070	COG1007	ATP synthesis coupled electron transport
FSW04_RS12110	COG3387	PFAM Glycoside hydrolase 15-related
FSW04_RS12115	COG0300	oxidoreductase activity
FSW04_RS12150	COG0640	Transcriptional regulator
FSW04_RS12155	COG0640	Transcriptional regulator
FSW04_RS12165	COG2409	Drug exporters of the RND superfamily
FSW04_RS12170	COG2226	methyltransferase
FSW04_RS12175	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSW04_RS12185	COG0730	response to heat
FSW04_RS12195	COG0640	Transcriptional regulator
FSW04_RS12200	COG0302	gtp cyclohydrolase
FSW04_RS12205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSW04_RS12210	COG0450	alkyl hydroperoxide reductase
FSW04_RS12215	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FSW04_RS12255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSW04_RS12260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FSW04_RS12315	COG2409	Drug exporters of the RND superfamily
FSW04_RS12355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS12365	COG2197	response regulator
FSW04_RS12370	COG3851	Histidine kinase
FSW04_RS12380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSW04_RS12385	COG0745	RESPONSE REGULATOR receiver
FSW04_RS12410	COG0437	4 iron, 4 sulfur cluster binding
FSW04_RS12415	COG0243	molybdopterin cofactor binding
FSW04_RS12415	COG3383	formate dehydrogenase (NAD+) activity
FSW04_RS12430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FSW04_RS12460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSW04_RS12465	COG1980	fructose-bisphosphate aldolase activity
FSW04_RS12480	COG1554	hydrolase, family 65, central catalytic
FSW04_RS12500	COG1131	(ABC) transporter
FSW04_RS12510	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS12535	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FSW04_RS12580	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FSW04_RS12585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSW04_RS12595	COG2235	arginine
FSW04_RS12600	COG0549	Belongs to the carbamate kinase family
FSW04_RS12625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FSW04_RS12625	COG4221	oxidoreductase activity
FSW04_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS12625	COG3321	synthase
FSW04_RS12630	COG0604	alcohol dehydrogenase
FSW04_RS12630	COG3321	synthase
FSW04_RS12645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSW04_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS12655	COG1819	glycosyl
FSW04_RS12670	COG1819	glycosyl
FSW04_RS12700	COG2197	response regulator
FSW04_RS12705	COG2197	response regulator
FSW04_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS12725	COG2409	Drug exporters of the RND superfamily
FSW04_RS12750	COG0604	alcohol dehydrogenase
FSW04_RS12765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSW04_RS12770	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FSW04_RS12795	COG2186	Transcriptional regulator
FSW04_RS12805	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FSW04_RS12810	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS12815	COG1024	Enoyl-CoA hydratase
FSW04_RS12820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS12835	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS12840	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS12845	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS12870	COG3119	arylsulfatase activity
FSW04_RS12875	COG3119	arylsulfatase activity
FSW04_RS12880	COG1309	transcriptional regulator
FSW04_RS12940	COG2080	2 iron, 2 sulfur cluster binding
FSW04_RS12945	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FSW04_RS12950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FSW04_RS12960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSW04_RS13000	COG1335	isochorismatase
FSW04_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSW04_RS13020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS13025	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13035	COG0066	3-isopropylmalate dehydratase activity
FSW04_RS13040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSW04_RS13055	COG2188	Transcriptional regulator
FSW04_RS13070	COG3321	synthase
FSW04_RS13070	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13070	COG0604	alcohol dehydrogenase
FSW04_RS13090	COG0154	amidase activity
FSW04_RS13100	COG2271	Major facilitator Superfamily
FSW04_RS13105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSW04_RS13140	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13150	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13180	COG1335	isochorismatase
FSW04_RS13185	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13195	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FSW04_RS13230	COG0154	amidase activity
FSW04_RS13235	COG1802	Transcriptional regulator
FSW04_RS13240	COG2301	Belongs to the HpcH HpaI aldolase family
FSW04_RS13245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS13265	COG1129	ABC transporter
FSW04_RS13315	COG0651	ATP synthesis coupled electron transport
FSW04_RS13320	COG0649	NAD binding
FSW04_RS13320	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FSW04_RS13325	COG3260	NADH ubiquinone oxidoreductase 20
FSW04_RS13430	COG2815	serine threonine protein kinase
FSW04_RS13430	COG0515	serine threonine protein kinase
FSW04_RS13480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FSW04_RS13485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSW04_RS13490	COG3300	MHYT domain
FSW04_RS13490	COG5001	Diguanylate cyclase
FSW04_RS13505	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FSW04_RS13520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FSW04_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS13590	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS13625	COG0726	polysaccharide deacetylase
FSW04_RS13635	COG1131	(ABC) transporter
FSW04_RS13660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSW04_RS13685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FSW04_RS13695	COG3845	ABC transporter
FSW04_RS13715	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FSW04_RS13760	COG2197	response regulator
FSW04_RS13780	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FSW04_RS13885	COG2172	sigma factor antagonist activity
FSW04_RS13925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FSW04_RS13930	COG2226	methyltransferase
FSW04_RS13970	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FSW04_RS14000	COG2909	trisaccharide binding
FSW04_RS14025	COG4251	negative regulation of phosphorylation
FSW04_RS14030	COG0784	Response regulator, receiver
FSW04_RS14035	COG5001	Diguanylate cyclase
FSW04_RS14090	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS14095	COG2172	sigma factor antagonist activity
FSW04_RS14130	COG2001	Belongs to the MraZ family
FSW04_RS14135	COG0275	rRNA processing
FSW04_RS14150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FSW04_RS14155	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FSW04_RS14160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FSW04_RS14165	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FSW04_RS14170	COG0772	Belongs to the SEDS family
FSW04_RS14175	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FSW04_RS14180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FSW04_RS14190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FSW04_RS14205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FSW04_RS14210	COG0509	glycine decarboxylation via glycine cleavage system
FSW04_RS14215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FSW04_RS14220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FSW04_RS14230	COG0180	Tryptophanyl-tRNA synthetase
FSW04_RS14235	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FSW04_RS14240	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FSW04_RS14260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FSW04_RS14265	COG1187	pseudouridine synthase activity
FSW04_RS14270	COG5001	Diguanylate cyclase
FSW04_RS14280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSW04_RS14285	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FSW04_RS14295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FSW04_RS14305	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FSW04_RS14310	COG1160	GTP binding
FSW04_RS14330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FSW04_RS14335	COG0242	peptide deformylase activity
FSW04_RS14340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FSW04_RS14345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSW04_RS14345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FSW04_RS14375	COG1136	(ABC) transporter
FSW04_RS14375	COG0577	efflux transmembrane transporter activity
FSW04_RS14380	COG0577	efflux transmembrane transporter activity
FSW04_RS14425	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSW04_RS14425	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FSW04_RS14430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FSW04_RS14440	COG0515	serine threonine protein kinase
FSW04_RS14445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FSW04_RS14450	COG1461	Dihydroxyacetone kinase
FSW04_RS14455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FSW04_RS14460	COG0742	ribosomal rna small subunit methyltransferase
FSW04_RS14465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FSW04_RS14475	COG1254	Belongs to the acylphosphatase family
FSW04_RS14525	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FSW04_RS14530	COG0416	fatty acid biosynthetic process
FSW04_RS14535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSW04_RS14540	COG0571	ribonuclease III activity
FSW04_RS14555	COG0552	protein localization to endoplasmic reticulum
FSW04_RS14570	COG4122	O-methyltransferase activity
FSW04_RS14575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FSW04_RS14580	COG0228	four-way junction DNA binding
FSW04_RS14585	COG1837	Belongs to the UPF0109 family
FSW04_RS14595	COG0336	Belongs to the RNA methyltransferase TrmD family
FSW04_RS14600	COG0335	large ribosomal subunit rRNA binding
FSW04_RS14615	COG0792	nuclease activity
FSW04_RS14630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSW04_RS14630	COG0758	DNA mediated transformation
FSW04_RS14685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FSW04_RS14690	COG1191	sigma factor activity
FSW04_RS14695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSW04_RS14720	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS14730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSW04_RS14745	COG0023	Translation Initiation Factor
FSW04_RS14760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FSW04_RS14765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FSW04_RS14770	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS14790	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS14800	COG1136	(ABC) transporter
FSW04_RS14800	COG0577	efflux transmembrane transporter activity
FSW04_RS14805	COG1136	(ABC) transporter
FSW04_RS14805	COG0577	efflux transmembrane transporter activity
FSW04_RS14810	COG0386	Belongs to the glutathione peroxidase family
FSW04_RS14835	COG0204	Acyl-transferase
FSW04_RS14850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FSW04_RS14860	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS14860	COG0022	dehydrogenase e1 component
FSW04_RS14865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS14870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FSW04_RS14890	COG1131	(ABC) transporter
FSW04_RS14915	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS14920	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS14930	COG0330	HflC and HflK could
FSW04_RS14955	COG4591	ABC-type transport system involved in lipoprotein release permease component
FSW04_RS14960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSW04_RS14965	COG1136	(ABC) transporter
FSW04_RS14965	COG0577	efflux transmembrane transporter activity
FSW04_RS14980	COG3118	belongs to the thioredoxin family
FSW04_RS15005	COG0477	Major facilitator Superfamily
FSW04_RS15030	COG1742	UPF0060 membrane protein
FSW04_RS15045	COG0626	cystathionine gamma-synthase activity
FSW04_RS15070	COG1024	Enoyl-CoA hydratase
FSW04_RS15075	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS15090	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS15095	COG0569	domain protein
FSW04_RS15095	COG0475	glutathione-regulated potassium exporter activity
FSW04_RS15105	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS15110	COG2197	response regulator
FSW04_RS15125	COG2072	flavoprotein involved in K transport
FSW04_RS15160	COG0745	RESPONSE REGULATOR receiver
FSW04_RS15165	COG2205	protein histidine kinase activity
FSW04_RS15175	COG2197	response regulator
FSW04_RS15190	COG0745	RESPONSE REGULATOR receiver
FSW04_RS15205	COG2197	response regulator
FSW04_RS15255	COG0745	RESPONSE REGULATOR receiver
FSW04_RS15260	COG0463	Glycosyl transferase, family 2
FSW04_RS15275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FSW04_RS15290	COG2181	nitrate reductase activity
FSW04_RS15300	COG1140	nitrate reductase beta subunit
FSW04_RS15375	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS15380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FSW04_RS15390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FSW04_RS15395	COG3706	GGDEF domain
FSW04_RS15405	COG2197	response regulator
FSW04_RS15410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FSW04_RS15415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FSW04_RS15420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSW04_RS15425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FSW04_RS15430	COG0072	phenylalanine-tRNA ligase activity
FSW04_RS15435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FSW04_RS15440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FSW04_RS15445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FSW04_RS15450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSW04_RS15455	COG0137	argininosuccinate synthase activity
FSW04_RS15465	COG0587	DNA-directed DNA polymerase activity
FSW04_RS15470	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FSW04_RS15480	COG2909	trisaccharide binding
FSW04_RS15485	COG1959	2 iron, 2 sulfur cluster binding
FSW04_RS15495	COG1131	(ABC) transporter
FSW04_RS15575	COG0210	DNA helicase
FSW04_RS15580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FSW04_RS15590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSW04_RS15595	COG0154	amidase activity
FSW04_RS15600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FSW04_RS15620	COG0028	Belongs to the TPP enzyme family
FSW04_RS15625	COG0440	acetolactate synthase activity
FSW04_RS15650	COG1472	Belongs to the glycosyl hydrolase 3 family
FSW04_RS15665	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FSW04_RS15670	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS15680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FSW04_RS15685	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FSW04_RS15690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSW04_RS15695	COG0366	Alpha amylase catalytic
FSW04_RS15725	COG3842	ATPase activity
FSW04_RS15735	COG1176	ABC-type spermidine putrescine transport system, permease component I
FSW04_RS15740	COG4585	Histidine kinase
FSW04_RS15750	COG0698	ribose 5-phosphate isomerase
FSW04_RS15755	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS15775	COG0217	transcriptional regulatory protein
FSW04_RS15800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FSW04_RS15805	COG0632	four-way junction helicase activity
FSW04_RS15810	COG2255	four-way junction helicase activity
FSW04_RS15825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSW04_RS15825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FSW04_RS15840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FSW04_RS15840	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FSW04_RS15845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FSW04_RS15850	COG0006	proline dipeptidase activity
FSW04_RS15865	COG0598	Magnesium transport protein CorA
FSW04_RS15885	COG2197	response regulator
FSW04_RS15890	COG3285	dna ligase
FSW04_RS15890	COG1793	dna ligase
FSW04_RS15905	COG1970	mechanosensitive ion channel activity
FSW04_RS15915	COG1234	tRNA 3'-trailer cleavage
FSW04_RS15920	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FSW04_RS15925	COG0540	Belongs to the ATCase OTCase family
FSW04_RS15930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FSW04_RS15935	COG0505	Belongs to the CarA family
FSW04_RS15955	COG0194	GDP metabolic process
FSW04_RS15970	COG0714	Associated with various cellular activities
FSW04_RS15990	COG0195	Participates in both transcription termination and antitermination
FSW04_RS16000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FSW04_RS16010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FSW04_RS16020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FSW04_RS16025	COG0196	riboflavin kinase activity
FSW04_RS16050	COG1185	polyribonucleotide nucleotidyltransferase activity
FSW04_RS16055	COG0612	Peptidase, M16
FSW04_RS16060	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FSW04_RS16085	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FSW04_RS16095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FSW04_RS16100	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FSW04_RS16110	COG2205	protein histidine kinase activity
FSW04_RS16115	COG0745	RESPONSE REGULATOR receiver
FSW04_RS16125	COG1426	Protein conserved in bacteria
FSW04_RS16130	COG1546	Belongs to the CinA family
FSW04_RS16130	COG1058	Belongs to the CinA family
FSW04_RS16145	COG2137	regulation of response to DNA damage stimulus
FSW04_RS16155	COG1418	mRNA catabolic process
FSW04_RS16160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FSW04_RS16170	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS16240	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FSW04_RS16250	COG0668	transmembrane transport
FSW04_RS16260	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSW04_RS16265	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FSW04_RS16270	COG2171	N-acyltransferase activity
FSW04_RS16275	COG0436	Aminotransferase
FSW04_RS16295	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FSW04_RS16300	COG0756	dUTP diphosphatase activity
FSW04_RS16320	COG1125	glycine betaine transport
FSW04_RS16320	COG0517	IMP dehydrogenase activity
FSW04_RS16395	COG0647	UMP catabolic process
FSW04_RS16405	COG2135	peptidase activity
FSW04_RS16430	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS16435	COG1132	(ABC) transporter
FSW04_RS16450	COG2197	response regulator
FSW04_RS16460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSW04_RS16465	COG1278	Cold shock
FSW04_RS16490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FSW04_RS16500	COG0596	Alpha beta hydrolase
FSW04_RS16520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FSW04_RS16555	COG0110	maltose O-acetyltransferase activity
FSW04_RS16575	COG0674	pyruvate-flavodoxin oxidoreductase activity
FSW04_RS16575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FSW04_RS16580	COG1013	pyruvate-flavodoxin oxidoreductase activity
FSW04_RS16590	COG0633	Ferredoxin
FSW04_RS16590	COG0543	2 iron, 2 sulfur cluster binding
FSW04_RS16610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS16620	COG2350	Protein conserved in bacteria
FSW04_RS16635	COG0586	Pfam SNARE associated Golgi protein
FSW04_RS16670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FSW04_RS16680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FSW04_RS16685	COG2313	pseudouridylate synthase activity
FSW04_RS16700	COG1595	DNA-templated transcription, initiation
FSW04_RS16715	COG1309	transcriptional regulator
FSW04_RS16785	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS16795	COG1309	transcriptional regulator
FSW04_RS16800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS16815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS16835	COG0513	Belongs to the DEAD box helicase family
FSW04_RS16860	COG0259	pyridoxamine-phosphate oxidase activity
FSW04_RS16865	COG0745	RESPONSE REGULATOR receiver
FSW04_RS16870	COG0436	Aminotransferase
FSW04_RS16915	COG3118	belongs to the thioredoxin family
FSW04_RS16920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FSW04_RS16925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FSW04_RS16955	COG2050	protein possibly involved in aromatic compounds catabolism
FSW04_RS16970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FSW04_RS16980	COG1716	ATPase activity
FSW04_RS16995	COG0442	prolyl-tRNA aminoacylation
FSW04_RS17010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FSW04_RS17040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FSW04_RS17045	COG0575	Belongs to the CDS family
FSW04_RS17050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FSW04_RS17055	COG0233	cytoplasmic translational termination
FSW04_RS17060	COG0528	UMP kinase activity
FSW04_RS17065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FSW04_RS17095	COG0564	pseudouridine synthase activity
FSW04_RS17100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSW04_RS17110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FSW04_RS17115	COG1799	cell septum assembly
FSW04_RS17120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FSW04_RS17135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS17185	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS17190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FSW04_RS17225	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FSW04_RS17235	COG2197	response regulator
FSW04_RS17240	COG2197	response regulator
FSW04_RS17260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FSW04_RS17260	COG0617	tRNA 3'-terminal CCA addition
FSW04_RS17260	COG0517	IMP dehydrogenase activity
FSW04_RS17270	COG0107	imidazoleglycerol-phosphate synthase activity
FSW04_RS17275	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FSW04_RS17280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FSW04_RS17285	COG0131	Imidazoleglycerol-phosphate dehydratase
FSW04_RS17290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSW04_RS17295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FSW04_RS17300	COG0124	histidyl-tRNA synthetase
FSW04_RS17305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FSW04_RS17325	COG0538	isocitrate dehydrogenase activity
FSW04_RS17355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FSW04_RS17360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FSW04_RS17365	COG2094	Belongs to the DNA glycosylase MPG family
FSW04_RS17370	COG0165	Argininosuccinate lyase
FSW04_RS17375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSW04_RS17385	COG0473	3-isopropylmalate dehydrogenase activity
FSW04_RS17390	COG3290	protein histidine kinase activity
FSW04_RS17390	COG0840	transmembrane signaling receptor activity
FSW04_RS17395	COG0066	3-isopropylmalate dehydratase activity
FSW04_RS17400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FSW04_RS17415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FSW04_RS17420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSW04_RS17440	COG1177	transmembrane transport
FSW04_RS17450	COG2197	response regulator
FSW04_RS17465	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS17470	COG2814	Major facilitator Superfamily
FSW04_RS17495	COG4129	membrane
FSW04_RS17510	COG3842	ATPase activity
FSW04_RS17520	COG0725	ABC transporter, periplasmic molybdate-binding protein
FSW04_RS17530	COG2188	Transcriptional regulator
FSW04_RS17535	COG0038	chloride channel
FSW04_RS17560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FSW04_RS17625	COG0582	viral genome integration into host DNA
FSW04_RS17720	COG1832	CoA-binding protein
FSW04_RS17735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS17755	COG0358	DNA primase activity
FSW04_RS17760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FSW04_RS17775	COG0574	Belongs to the PEP-utilizing enzyme family
FSW04_RS17775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSW04_RS17780	COG1381	Involved in DNA repair and RecF pathway recombination
FSW04_RS17790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FSW04_RS17805	COG4974	Belongs to the 'phage' integrase family
FSW04_RS17820	COG2195	Cleaves the N-terminal amino acid of tripeptides
FSW04_RS17825	COG0504	CTP synthase activity
FSW04_RS17830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FSW04_RS17835	COG0497	DNA recombination
FSW04_RS17840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FSW04_RS17860	COG0657	acetylesterase activity
FSW04_RS17865	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FSW04_RS17870	COG0142	geranyltranstransferase activity
FSW04_RS17880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FSW04_RS17885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FSW04_RS17950	COG0410	ABC transporter
FSW04_RS17975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FSW04_RS17985	COG0277	FAD linked oxidase domain protein
FSW04_RS17990	COG0579	oxidoreductase
FSW04_RS18000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSW04_RS18010	COG3191	aminopeptidase activity
FSW04_RS18035	COG2514	catechol 2,3-dioxygenase activity
FSW04_RS18095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSW04_RS18120	COG0583	DNA-binding transcription factor activity
FSW04_RS18140	COG0488	(ABC) transporter
FSW04_RS18145	COG2814	Major facilitator Superfamily
FSW04_RS18150	COG1063	alcohol dehydrogenase
FSW04_RS18245	COG4585	Histidine kinase
FSW04_RS18250	COG0709	Synthesizes selenophosphate from selenide and ATP
FSW04_RS18290	COG0437	4 iron, 4 sulfur cluster binding
FSW04_RS18295	COG3383	formate dehydrogenase (NAD+) activity
FSW04_RS18295	COG0243	molybdopterin cofactor binding
FSW04_RS18305	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS18310	COG0513	Belongs to the DEAD box helicase family
FSW04_RS18315	COG0776	regulation of translation
FSW04_RS18320	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS18340	COG0302	gtp cyclohydrolase
FSW04_RS18350	COG2205	protein histidine kinase activity
FSW04_RS18375	COG2205	protein histidine kinase activity
FSW04_RS18380	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FSW04_RS18385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FSW04_RS18390	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FSW04_RS18410	COG4251	negative regulation of phosphorylation
FSW04_RS18435	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS18465	COG1396	sequence-specific DNA binding
FSW04_RS18480	COG0657	acetylesterase activity
FSW04_RS18490	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSW04_RS18500	COG1121	(ABC) transporter
FSW04_RS18505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FSW04_RS18510	COG0735	belongs to the Fur family
FSW04_RS18540	COG0006	proline dipeptidase activity
FSW04_RS18545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FSW04_RS18550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FSW04_RS18555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FSW04_RS18585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FSW04_RS18610	COG4968	Prepilin-type N-terminal cleavage methylation domain
FSW04_RS18620	COG0482	sulfurtransferase activity
FSW04_RS18625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FSW04_RS18630	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FSW04_RS18635	COG3706	GGDEF domain
FSW04_RS18660	COG1459	type II secretion system
FSW04_RS18665	COG1459	type II secretion system
FSW04_RS18675	COG0667	Aldo Keto reductase
FSW04_RS18680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSW04_RS18685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FSW04_RS18690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FSW04_RS18695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FSW04_RS18700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FSW04_RS18705	COG0482	sulfurtransferase activity
FSW04_RS18705	COG0822	iron-sulfur transferase activity
FSW04_RS18720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FSW04_RS18730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS18745	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS18760	COG2326	polyphosphate kinase activity
FSW04_RS18765	COG3304	Inner membrane component domain
FSW04_RS18775	COG1304	FMN binding
FSW04_RS18780	COG2258	MOSC domain
FSW04_RS18800	COG0585	pseudouridine synthase activity
FSW04_RS18810	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS18865	COG0596	Alpha beta hydrolase
FSW04_RS19025	COG0477	Major facilitator Superfamily
FSW04_RS19035	COG0252	asparaginase activity
FSW04_RS19045	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS19055	COG2205	protein histidine kinase activity
FSW04_RS19060	COG0745	RESPONSE REGULATOR receiver
FSW04_RS19105	COG0477	Major facilitator Superfamily
FSW04_RS19110	COG0789	Transcriptional regulator
FSW04_RS19125	COG0745	RESPONSE REGULATOR receiver
FSW04_RS19145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSW04_RS19160	COG1132	(ABC) transporter
FSW04_RS19165	COG1132	(ABC) transporter
FSW04_RS19185	COG1024	Enoyl-CoA hydratase
FSW04_RS19195	COG0569	domain protein
FSW04_RS19200	COG0569	domain protein
FSW04_RS19205	COG0531	amino acid
FSW04_RS19220	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FSW04_RS19230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSW04_RS19235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FSW04_RS19270	COG0802	atpase or kinase
FSW04_RS19285	COG0789	Transcriptional regulator
FSW04_RS19305	COG0640	Transcriptional regulator
FSW04_RS19320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FSW04_RS19325	COG1278	Cold shock
FSW04_RS19345	COG2197	response regulator
FSW04_RS19355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FSW04_RS19360	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSW04_RS19380	COG2890	protein-(glutamine-N5) methyltransferase activity
FSW04_RS19420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS19425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS19425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS19450	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS19475	COG2226	methyltransferase
FSW04_RS19500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FSW04_RS19500	COG2755	lipolytic protein G-D-S-L family
FSW04_RS19510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FSW04_RS19515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS19540	COG0596	Alpha beta hydrolase
FSW04_RS19540	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS19550	COG0442	prolyl-tRNA aminoacylation
FSW04_RS19575	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS19575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS19575	COG1703	isobutyryl-CoA mutase activity
FSW04_RS19590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FSW04_RS19650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FSW04_RS19655	COG4981	capsule polysaccharide biosynthetic process
FSW04_RS19680	COG1215	transferase activity, transferring glycosyl groups
FSW04_RS19685	COG0024	Methionine aminopeptidase
FSW04_RS19700	COG1078	dGTPase activity
FSW04_RS19715	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS19720	COG2267	carboxylic ester hydrolase activity
FSW04_RS19725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FSW04_RS19750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS19755	COG1573	uracil-dna glycosylase
FSW04_RS19760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FSW04_RS19765	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FSW04_RS19770	COG1392	Phosphate transport regulator
FSW04_RS19815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FSW04_RS19830	COG1194	a g-specific adenine glycosylase
FSW04_RS19835	COG0556	nucleotide-excision repair
FSW04_RS19850	COG0640	Transcriptional regulator
FSW04_RS19860	COG0237	dephospho-CoA kinase activity
FSW04_RS19865	COG0539	negative regulation of cytoplasmic translation
FSW04_RS19885	COG1090	epimerase
FSW04_RS19925	COG0159	tryptophan synthase activity
FSW04_RS19935	COG0133	tryptophan synthase activity
FSW04_RS19940	COG0135	phosphoribosylanthranilate isomerase activity
FSW04_RS19945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS19950	COG0134	indole-3-glycerol-phosphate synthase activity
FSW04_RS19955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FSW04_RS19960	COG0512	Glutamine amidotransferase of anthranilate synthase
FSW04_RS19965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FSW04_RS19970	COG0140	phosphoribosyl-ATP diphosphatase activity
FSW04_RS19970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FSW04_RS19995	COG1131	(ABC) transporter
FSW04_RS20005	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FSW04_RS20010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FSW04_RS20025	COG0791	NLP P60 protein
FSW04_RS20030	COG1252	NADH dehydrogenase
FSW04_RS20040	COG2264	protein methyltransferase activity
FSW04_RS20045	COG0484	heat shock protein binding
FSW04_RS20050	COG1420	regulation of RNA biosynthetic process
FSW04_RS20060	COG2030	dehydratase
FSW04_RS20065	COG0697	spore germination
FSW04_RS20070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSW04_RS20080	COG0481	GTPase activity
FSW04_RS20085	COG0728	peptidoglycan biosynthetic process
FSW04_RS20090	COG0268	Binds directly to 16S ribosomal RNA
FSW04_RS20185	COG1596	polysaccharide export
FSW04_RS20185	COG1555	photosystem II stabilization
FSW04_RS20215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSW04_RS20225	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FSW04_RS20230	COG0799	negative regulation of ribosome biogenesis
FSW04_RS20235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FSW04_RS20240	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FSW04_RS20250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FSW04_RS20255	COG4221	oxidoreductase activity
FSW04_RS20275	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FSW04_RS20280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FSW04_RS20285	COG1530	ribonuclease E activity
FSW04_RS20290	COG0772	Belongs to the SEDS family
FSW04_RS20295	COG0768	penicillin binding
FSW04_RS20310	COG1077	Cell shape determining protein MreB Mrl
FSW04_RS20320	COG0424	maF-like protein
FSW04_RS20325	COG0105	UTP biosynthetic process
FSW04_RS20335	COG0285	dihydrofolate synthase activity
FSW04_RS20340	COG0525	valine-tRNA ligase activity
FSW04_RS20345	COG4106	trans-aconitate 2-methyltransferase activity
FSW04_RS20360	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FSW04_RS20365	COG0740	serine-type endopeptidase activity
FSW04_RS20370	COG0544	peptidyl-prolyl cis-trans isomerase activity
FSW04_RS20395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSW04_RS20400	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FSW04_RS20405	COG1643	Atp-dependent helicase
FSW04_RS20415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FSW04_RS20430	COG2301	Belongs to the HpcH HpaI aldolase family
FSW04_RS20440	COG1063	alcohol dehydrogenase
FSW04_RS20445	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS20460	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS20465	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS20470	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FSW04_RS20480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS20490	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS20495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FSW04_RS20515	COG0022	dehydrogenase e1 component
FSW04_RS20520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS20525	COG1309	transcriptional regulator
FSW04_RS20535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS20540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS20555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FSW04_RS20560	COG0508	dehydrogenase complex catalyzes the overall conversion of
FSW04_RS20565	COG0022	dehydrogenase e1 component
FSW04_RS20570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FSW04_RS20580	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS20605	COG1309	transcriptional regulator
FSW04_RS20615	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS20620	COG2072	flavoprotein involved in K transport
FSW04_RS20635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FSW04_RS20650	COG0596	Alpha beta hydrolase
FSW04_RS20660	COG0596	Alpha beta hydrolase
FSW04_RS20675	COG1546	Belongs to the CinA family
FSW04_RS20675	COG1058	Belongs to the CinA family
FSW04_RS20775	COG3263	regulation of cellular component size
FSW04_RS20815	COG1522	sequence-specific DNA binding
FSW04_RS20870	COG0436	Aminotransferase
FSW04_RS20895	COG2323	membrane
FSW04_RS20925	COG5001	Diguanylate cyclase
FSW04_RS20930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FSW04_RS20945	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS20960	COG1802	Transcriptional regulator
FSW04_RS20965	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS20975	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS21000	COG1022	Amp-dependent synthetase and ligase
FSW04_RS21005	COG2409	Drug exporters of the RND superfamily
FSW04_RS21025	COG0306	phosphate transporter
FSW04_RS21035	COG3845	ABC transporter
FSW04_RS21085	COG0745	RESPONSE REGULATOR receiver
FSW04_RS21100	COG5002	protein histidine kinase activity
FSW04_RS21105	COG0745	RESPONSE REGULATOR receiver
FSW04_RS21150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FSW04_RS21160	COG2197	response regulator
FSW04_RS21205	COG1294	oxidase, subunit
FSW04_RS21210	COG4988	ABC transporter
FSW04_RS21215	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FSW04_RS21230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FSW04_RS21265	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FSW04_RS21280	COG3932	Exopolysaccharide synthesis, ExoD
FSW04_RS21285	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS21295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS21310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FSW04_RS21325	COG0069	glutamate synthase activity
FSW04_RS21340	COG2226	methyltransferase
FSW04_RS21345	COG1793	dna ligase
FSW04_RS21390	COG0463	Glycosyl transferase, family 2
FSW04_RS21405	COG0446	pyridine nucleotide-disulphide oxidoreductase
FSW04_RS21495	COG1914	H( )-stimulated, divalent metal cation uptake system
FSW04_RS21520	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FSW04_RS21520	COG1672	PFAM Archaeal ATPase
FSW04_RS21555	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS21560	COG1595	DNA-templated transcription, initiation
FSW04_RS21595	COG1595	DNA-templated transcription, initiation
FSW04_RS21605	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSW04_RS21610	COG1024	Enoyl-CoA hydratase
FSW04_RS21615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FSW04_RS21625	COG0109	protoheme IX farnesyltransferase activity
FSW04_RS21640	COG2207	Transcriptional regulator
FSW04_RS21685	COG2814	Major facilitator Superfamily
FSW04_RS21700	COG0537	adenosine 5'-monophosphoramidase activity
FSW04_RS21705	COG2234	aminopeptidase activity
FSW04_RS21720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FSW04_RS21725	COG2239	Acts as a magnesium transporter
FSW04_RS21730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FSW04_RS21730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FSW04_RS21735	COG0736	holo-[acyl-carrier-protein] synthase activity
FSW04_RS21740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FSW04_RS21745	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FSW04_RS21750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FSW04_RS21755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FSW04_RS21770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FSW04_RS21780	COG0519	Catalyzes the synthesis of GMP from XMP
FSW04_RS21780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSW04_RS21785	COG0516	GMP reductase activity
FSW04_RS21790	COG1105	Belongs to the carbohydrate kinase PfkB family
FSW04_RS21800	COG0741	lytic transglycosylase activity
FSW04_RS21800	COG1388	LysM domain
FSW04_RS21805	COG0284	orotidine-5'-phosphate decarboxylase activity
FSW04_RS21815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FSW04_RS21820	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FSW04_RS21825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FSW04_RS21830	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FSW04_RS21855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FSW04_RS21875	COG0673	inositol 2-dehydrogenase activity
FSW04_RS21880	COG2197	response regulator
FSW04_RS21885	COG2084	Dehydrogenase
FSW04_RS21910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSW04_RS21925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FSW04_RS21935	COG2197	response regulator
FSW04_RS21975	COG0740	serine-type endopeptidase activity
FSW04_RS21985	COG0640	Transcriptional regulator
FSW04_RS21995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FSW04_RS22000	COG2234	aminopeptidase activity
FSW04_RS22025	COG3030	protein affecting phage T7 exclusion by the F plasmid
FSW04_RS22040	COG1802	Transcriptional regulator
FSW04_RS22045	COG1335	isochorismatase
FSW04_RS22085	COG0492	ferredoxin-NADP+ reductase activity
FSW04_RS22110	COG0070	glutamate synthase
FSW04_RS22110	COG0069	glutamate synthase activity
FSW04_RS22110	COG0067	glutamate synthase
FSW04_RS22125	COG1366	Belongs to the anti-sigma-factor antagonist family
FSW04_RS22150	COG0693	protein deglycase activity
FSW04_RS22205	COG1295	ribonuclease BN
FSW04_RS22210	COG1074	ATP-dependent DNA helicase activity
FSW04_RS22225	COG0551	DNA topoisomerase type I activity
FSW04_RS22225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FSW04_RS22230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS22235	COG0768	penicillin binding
FSW04_RS22255	COG0842	Transport permease protein
FSW04_RS22255	COG1716	ATPase activity
FSW04_RS22255	COG1131	(ABC) transporter
FSW04_RS22260	COG1192	Involved in chromosome partitioning
FSW04_RS22270	COG0083	homoserine kinase activity
FSW04_RS22275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FSW04_RS22280	COG0460	homoserine dehydrogenase
FSW04_RS22300	COG0739	heme binding
FSW04_RS22305	COG0501	Belongs to the peptidase M48B family
FSW04_RS22315	COG2208	phosphoserine phosphatase activity
FSW04_RS22360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS22365	COG1570	exodeoxyribonuclease VII activity
FSW04_RS22370	COG1722	exodeoxyribonuclease VII activity
FSW04_RS22375	COG4948	Mandelate Racemase Muconate Lactonizing
FSW04_RS22380	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS22395	COG1253	flavin adenine dinucleotide binding
FSW04_RS22400	COG2154	pterin-4-alpha-carbinolamine dehydratase
FSW04_RS22405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FSW04_RS22420	COG1595	DNA-templated transcription, initiation
FSW04_RS22430	COG1595	DNA-templated transcription, initiation
FSW04_RS22435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FSW04_RS22450	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS22465	COG2818	Glycosylase
FSW04_RS22500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FSW04_RS22505	COG0215	cysteine-tRNA ligase activity
FSW04_RS22510	COG0745	RESPONSE REGULATOR receiver
FSW04_RS22525	COG0493	'glutamate synthase
FSW04_RS22525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FSW04_RS22580	COG0673	inositol 2-dehydrogenase activity
FSW04_RS22595	COG2244	polysaccharide biosynthetic process
FSW04_RS22640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS22660	COG0463	Glycosyl transferase, family 2
FSW04_RS22670	COG2197	response regulator
FSW04_RS22680	COG2197	response regulator
FSW04_RS22685	COG2201	protein-glutamate methylesterase activity
FSW04_RS22690	COG2205	protein histidine kinase activity
FSW04_RS22695	COG2197	response regulator
FSW04_RS22710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FSW04_RS22710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FSW04_RS22715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FSW04_RS22720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FSW04_RS22730	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FSW04_RS22735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FSW04_RS22745	COG0626	cystathionine gamma-synthase activity
FSW04_RS22755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FSW04_RS22765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FSW04_RS22775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FSW04_RS22785	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FSW04_RS22805	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FSW04_RS22815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FSW04_RS22820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FSW04_RS22825	COG3022	response to hydroperoxide
FSW04_RS22835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FSW04_RS22840	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FSW04_RS22845	COG0037	tRNA processing
FSW04_RS22850	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FSW04_RS22865	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FSW04_RS22875	COG2951	lytic endotransglycosylase activity
FSW04_RS22885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FSW04_RS22890	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FSW04_RS22895	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS22910	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS22930	COG0387	Pfam Sodium calcium exchanger
FSW04_RS22945	COG0003	Pfam Anion-transporting ATPase
FSW04_RS22975	COG0542	response to heat
FSW04_RS22985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FSW04_RS22990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FSW04_RS22995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FSW04_RS23000	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FSW04_RS23020	COG0156	8-amino-7-oxononanoate synthase activity
FSW04_RS23090	COG1127	ABC transporter
FSW04_RS23095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSW04_RS23100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FSW04_RS23110	COG3835	regulator
FSW04_RS23115	COG0347	Belongs to the P(II) protein family
FSW04_RS23120	COG0004	ammonium transporteR
FSW04_RS23140	COG0646	methionine synthase
FSW04_RS23140	COG1410	methionine synthase
FSW04_RS23150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FSW04_RS23155	COG2304	oxidoreductase activity
FSW04_RS23160	COG0714	Associated with various cellular activities
FSW04_RS23170	COG2304	oxidoreductase activity
FSW04_RS23180	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS23195	COG0316	Belongs to the HesB IscA family
FSW04_RS23215	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FSW04_RS23220	COG1063	alcohol dehydrogenase
FSW04_RS23225	COG1063	alcohol dehydrogenase
FSW04_RS23230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FSW04_RS23235	COG1307	EDD domain protein, DegV family
FSW04_RS23240	COG0628	permease
FSW04_RS23270	COG2195	Cleaves the N-terminal amino acid of tripeptides
FSW04_RS23280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FSW04_RS23285	COG3246	L-lysine catabolic process to acetate
FSW04_RS23290	COG2738	Putative neutral zinc metallopeptidase
FSW04_RS23295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS23310	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS23315	COG0433	COG0433 Predicted ATPase
FSW04_RS23320	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS23355	COG0346	lactoylglutathione lyase activity
FSW04_RS23375	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FSW04_RS23380	COG1024	Enoyl-CoA hydratase
FSW04_RS23385	COG0653	protein targeting
FSW04_RS23390	COG2197	response regulator
FSW04_RS23395	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS23405	COG0156	8-amino-7-oxononanoate synthase activity
FSW04_RS23430	COG0477	Major facilitator Superfamily
FSW04_RS23440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSW04_RS23445	COG1773	rubredoxin
FSW04_RS23455	COG1902	pentaerythritol trinitrate reductase activity
FSW04_RS23475	COG0183	Belongs to the thiolase family
FSW04_RS23505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FSW04_RS23505	COG2199	diguanylate cyclase activity
FSW04_RS23535	COG1595	DNA-templated transcription, initiation
FSW04_RS23545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FSW04_RS23565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FSW04_RS23590	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FSW04_RS23595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FSW04_RS23600	COG0101	tRNA pseudouridine synthase activity
FSW04_RS23605	COG0203	ribosomal protein L17
FSW04_RS23610	COG0202	RNA polymerase activity
FSW04_RS23615	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FSW04_RS23620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FSW04_RS23625	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FSW04_RS23630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FSW04_RS23640	COG0563	adenylate kinase activity
FSW04_RS23645	COG0201	protein transport
FSW04_RS23655	COG0200	Binds to the 23S rRNA
FSW04_RS23660	COG1841	ribosomal large subunit assembly
FSW04_RS23665	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FSW04_RS23670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FSW04_RS23675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FSW04_RS23680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FSW04_RS23690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FSW04_RS23700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FSW04_RS23710	COG0255	Belongs to the universal ribosomal protein uL29 family
FSW04_RS23715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FSW04_RS23720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FSW04_RS23730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FSW04_RS23735	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FSW04_RS23740	COG0089	rRNA binding
FSW04_RS23745	COG0088	Forms part of the polypeptide exit tunnel
FSW04_RS23750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FSW04_RS23755	COG0051	transcription antitermination factor activity, RNA binding
FSW04_RS23760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FSW04_RS23765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FSW04_RS23780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FSW04_RS23785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS23800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FSW04_RS23820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FSW04_RS23825	COG0085	RNA polymerase activity
FSW04_RS23835	COG0222	ribosome binding
FSW04_RS23840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FSW04_RS23845	COG0081	regulation of translation
FSW04_RS23850	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FSW04_RS23855	COG0250	Participates in transcription elongation, termination and antitermination
FSW04_RS23865	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FSW04_RS23870	COG1305	Transglutaminase-like
FSW04_RS23885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FSW04_RS23885	COG0519	Catalyzes the synthesis of GMP from XMP
FSW04_RS23900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FSW04_RS23910	COG1309	transcriptional regulator
FSW04_RS23915	COG1053	succinate dehydrogenase
FSW04_RS23920	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS23925	COG0681	Belongs to the peptidase S26 family
FSW04_RS23960	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS23965	COG0586	Pfam SNARE associated Golgi protein
FSW04_RS23985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FSW04_RS23995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS24005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FSW04_RS24005	COG0784	Response regulator, receiver
FSW04_RS24005	COG2205	protein histidine kinase activity
FSW04_RS24005	COG2198	Histidine kinase
FSW04_RS24010	COG0745	RESPONSE REGULATOR receiver
FSW04_RS24015	COG0463	Glycosyl transferase, family 2
FSW04_RS24045	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS24080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FSW04_RS24100	COG1309	transcriptional regulator
FSW04_RS24110	COG3415	Transposase
FSW04_RS24110	COG2801	Transposase and inactivated derivatives
FSW04_RS24130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS24130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FSW04_RS24135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FSW04_RS24200	COG0745	RESPONSE REGULATOR receiver
FSW04_RS24205	COG2205	protein histidine kinase activity
FSW04_RS24215	COG2205	protein histidine kinase activity
FSW04_RS24235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FSW04_RS24255	COG0477	Major facilitator Superfamily
FSW04_RS24300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FSW04_RS24310	COG1562	ergosterol biosynthetic process
FSW04_RS24315	COG1657	PFAM Prenyltransferase squalene oxidase
FSW04_RS24335	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS24340	COG2070	2-Nitropropane dioxygenase
FSW04_RS24385	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS24390	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS24395	COG1024	Enoyl-CoA hydratase
FSW04_RS24400	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS24420	COG1454	alcohol dehydrogenase
FSW04_RS24430	COG0477	Major facilitator Superfamily
FSW04_RS24435	COG0583	DNA-binding transcription factor activity
FSW04_RS24500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FSW04_RS24505	COG0601	transmembrane transport
FSW04_RS24525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FSW04_RS24535	COG1486	melibiose metabolic process
FSW04_RS24550	COG3962	Belongs to the TPP enzyme family
FSW04_RS24555	COG1012	belongs to the aldehyde dehydrogenase family
FSW04_RS24560	COG0673	inositol 2-dehydrogenase activity
FSW04_RS24570	COG1609	Transcriptional regulator
FSW04_RS24670	COG1595	DNA-templated transcription, initiation
FSW04_RS24675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FSW04_RS24685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FSW04_RS24690	COG5006	permease, DMT superfamily
FSW04_RS24725	COG3437	response regulator, receiver
FSW04_RS24750	COG0740	serine-type endopeptidase activity
FSW04_RS24755	COG0584	glycerophosphoryl diester phosphodiesterase
FSW04_RS24760	COG0179	Fumarylacetoacetate (FAA) hydrolase
FSW04_RS24780	COG0477	Major facilitator Superfamily
FSW04_RS24790	COG1678	Uncharacterized ACR, COG1678
FSW04_RS24805	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS24820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FSW04_RS24830	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FSW04_RS24835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FSW04_RS24840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FSW04_RS24865	COG1764	response to oxidative stress
FSW04_RS24900	COG1716	ATPase activity
FSW04_RS24900	COG0842	Transport permease protein
FSW04_RS24900	COG1131	(ABC) transporter
FSW04_RS24910	COG0277	FAD linked oxidase domain protein
FSW04_RS24950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FSW04_RS24960	COG3387	PFAM Glycoside hydrolase 15-related
FSW04_RS24965	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS24970	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS24980	COG0235	Class ii aldolase
FSW04_RS24990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FSW04_RS25020	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS25040	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS25055	COG0511	ligase activity, forming carbon-carbon bonds
FSW04_RS25060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FSW04_RS25065	COG1024	Enoyl-CoA hydratase
FSW04_RS25090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS25100	COG0574	Belongs to the PEP-utilizing enzyme family
FSW04_RS25100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FSW04_RS25110	COG1250	3-hydroxyacyl-CoA dehydrogenase
FSW04_RS25120	COG1960	acyl-CoA dehydrogenase activity
FSW04_RS25125	COG0183	Belongs to the thiolase family
FSW04_RS25130	COG1024	Enoyl-CoA hydratase
FSW04_RS25140	COG1024	Enoyl-CoA hydratase
FSW04_RS25145	COG0318	PFAM AMP-dependent synthetase and ligase
FSW04_RS25195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS25200	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS25215	COG4214	carbohydrate transport
FSW04_RS25220	COG1129	ABC transporter
FSW04_RS25225	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS25250	COG0596	Alpha beta hydrolase
FSW04_RS25270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS25275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FSW04_RS25280	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FSW04_RS25285	COG0145	ligase activity
FSW04_RS25300	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS25340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSW04_RS25345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FSW04_RS25355	COG0438	transferase activity, transferring glycosyl groups
FSW04_RS25360	COG0363	glucosamine-6-phosphate deaminase activity
FSW04_RS25375	COG1959	2 iron, 2 sulfur cluster binding
FSW04_RS25375	COG1295	ribonuclease BN
FSW04_RS25395	COG1028	Short-chain dehydrogenase reductase Sdr
FSW04_RS25405	COG1028	Short-chain dehydrogenase reductase Sdr